SUID	annotation.Taxon	AverageShortestPathLength	BetweennessCentrality	bg.annotation.DbId	bg.annotation.DbRelease	bg.annotation.Description	bg.annotation.EntityType	bg.annotation.GO	bg.annotation.ID	bg.annotation.InputName	bg.annotation.IsSeed	bg.annotation.KEGG	bg.annotation.Name	bg.annotation.SourceOrganism	bg.annotation.XNames	ClosenessCentrality	ClusteringCoefficient	Degree	Eccentricity	IsSingleNode	Matching.Attribute	name	NeighborhoodConnectivity	NumberOfDirectedEdges	NumberOfUndirectedEdges	PartnerOfMultiEdgedNodePairs	Radiality	selected	SelfLoops	shared name	Stress	TopologicalCoefficient
787651	taxon:9606	1.82479912	0.05709037	179011	1902	neurotrophic receptor tyrosine kinase 1	gene	biological_process-&-1&-GO:0007611-&&-learning or memory-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0021553-&&-olfactory nerve development-%%-GO:0009314-&&-response to radiation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0007411-&&-axon guidance-%%-GO:0045471-&&-response to ethanol-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0051599-&&-response to hydrostatic pressure-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0042493-&&-response to drug-%%-GO:0061368-&&-behavioral response to formalin induced pain-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0042490-&&-mechanoreceptor differentiation-%%-GO:0060385-&&-axonogenesis involved in innervation-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0010623-&&-programmed cell death involved in cell development-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0007568-&&-aging-%%-GO:0030183-&&-B cell differentiation-%%-GO:0007623-&&-circadian rhythm-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048678-&&-response to axon injury-%%-GO:0014823-&&-response to activity-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0000186-&&-activation of MAPKK activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0009986-&&-cell surface-%%-GO:0043234-&&-protein complex-%%-GO:0043235-&&-receptor complex-%%-GO:0005769-&&-early endosome-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005770-&&-late endosome-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0043121-&&-neurotrophin binding-%%-GO:0005166-&&-neurotrophin p75 receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0010465-&&-nerve growth factor receptor activity-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0019900-&&-kinase binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0048406-&&-nerve growth factor binding	G:9606:NTRK1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	NTRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTRK1	0.54800553	0.02418919	1467	4	FALSE	NTRK1	NTRK1	83.58703072	0	1466	0	0.86253348	FALSE	1	NTRK1	67292950	0.01395829
791992	taxon:9606	1.90641248	0.05254981	182757	1902	amyloid beta precursor protein	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0006417-&&-regulation of translation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0007626-&&-locomotory behavior-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0006897-&&-endocytosis-%%-GO:0008542-&&-visual learning-%%-GO:0016358-&&-dendrite development-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0048669-&&-collateral sprouting in absence of injury-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0016322-&&-neuron remodeling-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007611-&&-learning or memory-%%-GO:0007409-&&-axonogenesis-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0007617-&&-mating behavior-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0050803-&&-regulation of synapse structure or activity-%%-GO:0071874-&&-cellular response to norepinephrine stimulus-%%-GO:0006979-&&-response to oxidative stress-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0051563-&&-smooth endoplasmic reticulum calcium ion homeostasis-%%-GO:0010288-&&-response to lead ion-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031175-&&-neuron projection development-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0008088-&&-axo-dendritic transport-%%-GO:0051124-&&-synaptic growth at neuromuscular junction-%%-GO:0030900-&&-forebrain development-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0001967-&&-suckling behavior-%%-GO:0007155-&&-cell adhesion-%%-GO:0050808-&&-synapse organization-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0009987-&&-cellular process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1990761-&&-growth cone lamellipodium-%%-GO:0045121-&&-membrane raft-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043197-&&-dendritic spine-%%-GO:1990812-&&-growth cone filopodium-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0043195-&&-terminal bouton-%%-GO:0005768-&&-endosome-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005576-&&-extracellular region-%%-GO:0031904-&&-endosome lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0045177-&&-apical part of cell-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030424-&&-axon-%%-GO:0097449-&&-astrocyte projection-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0044304-&&-main axon-%%-GO:0051233-&&-spindle midzone-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051425-&&-PTB domain binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0008201-&&-heparin binding	G:9606:APP			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04726-&&-Serotonergic synapse	APP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APP	0.52454545	0.01466175	1007	4	FALSE	APP	APP	67.75124378	0	1006	0	0.84893125	FALSE	1	APP	48533772	0.01147525
788708	taxon:9606	1.92122262	0.03639996	177146	1902	tumor protein p53	gene	biological_process-&-1&-GO:0010332-&&-response to gamma radiation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051097-&&-negative regulation of helicase activity-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0008283-&&-cell proliferation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0051262-&&-protein tetramerization-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0097252-&&-oligodendrocyte apoptotic process-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006284-&&-base-excision repair-%%-GO:0048512-&&-circadian behavior-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0090399-&&-replicative senescence-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0031497-&&-chromatin assembly-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0008104-&&-protein localization-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0090403-&&-oxidative stress-induced premature senescence-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0046677-&&-response to antibiotic-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006983-&&-ER overload response-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0070245-&&-positive regulation of thymocyte apoptotic process-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010165-&&-response to X-ray-%%-GO:0007569-&&-cell aging-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005657-&&-replication fork-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0016605-&&-PML body-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0002020-&&-protease binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0043621-&&-protein self-association	G:9606:TP53	TP53	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05216-&&-Thyroid cancer-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04216-&&-Ferroptosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TP53	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53	0.52050189	0.03374014	944	4	FALSE	TP53	TP53	96.14118896	0	943	0	0.8464629	FALSE	1	TP53	41204990	0.01630954
792787	taxon:9606	1.91318733	0.04269861	181367	1902	epidermal growth factor receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0016101-&&-diterpenoid metabolic process-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0001503-&&-ossification-%%-GO:0007494-&&-midgut development-%%-GO:0030324-&&-lung development-%%-GO:0042060-&&-wound healing-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0033590-&&-response to cobalamin-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0035690-&&-cellular response to drug-%%-GO:0033594-&&-response to hydroxyisoflavone-%%-GO:0007165-&&-signal transduction-%%-GO:0043586-&&-tongue development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051592-&&-response to calcium ion-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:1900020-&&-positive regulation of protein kinase C activity-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0048143-&&-astrocyte activation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0010960-&&-magnesium ion homeostasis-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0001942-&&-hair follicle development-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0061024-&&-membrane organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006950-&&-response to stress-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0042743-&&-hydrogen peroxide metabolic process-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0070141-&&-response to UV-A-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0042698-&&-ovulation cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060571-&&-morphogenesis of an epithelial fold-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:1905208-&&-negative regulation of cardiocyte differentiation-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0007611-&&-learning or memory-%%-GO:0051205-&&-protein insertion into membrane-%%-GO:0043006-&&-activation of phospholipase A2 activity by calcium-mediated signaling-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0007623-&&-circadian rhythm-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006412-&&-translation-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:1902722-&&-positive regulation of prolactin secretion-%%-GO:0045739-&&-positive regulation of DNA repair|cellular_component-&-1&-GO:0097489-&&-multivesicular body, internal vesicle lumen-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0043235-&&-receptor complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0031965-&&-nuclear membrane-%%-GO:0045202-&&-synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0070435-&&-Shc-EGFR complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005006-&&-epidermal growth factor-activated receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0048408-&&-epidermal growth factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0051015-&&-actin filament binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:EGFR	EGFR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	EGFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGFR	0.52268797	0.02108175	932	4	FALSE	EGFR	EGFR	75.59462366	0	931	0	0.84780211	FALSE	1	EGFR	41576904	0.01270937
788935	taxon:9606	1.94690405	0.01880816	176567	1902	cullin 3	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045842-&&-positive regulation of mitotic metaphase/anaphase transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0030030-&&-cell projection organization-%%-GO:0001831-&&-trophectodermal cellular morphogenesis-%%-GO:0007369-&&-gastrulation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0072576-&&-liver morphogenesis-%%-GO:0017145-&&-stem cell division-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0044346-&&-fibroblast apoptotic process-%%-GO:0071630-&&-ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005827-&&-polar microtubule-%%-GO:0016020-&&-membrane-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005112-&&-Notch binding-%%-GO:0031208-&&-POZ domain binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CUL3			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CUL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL3	0.513636	0.04284105	910	4	FALSE	CUL3	CUL3	102.6310573	0	909	0	0.84218266	FALSE	1	CUL3	26278972	0.01777393
788894	taxon:9606	1.96281708	0.02138319	176662	1902	exportin 1	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000055-&&-ribosomal large subunit export from nucleus-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0000054-&&-ribosomal subunit export from nucleus-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0016032-&&-viral process-%%-GO:0075733-&&-intracellular transport of virus|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0015030-&&-Cajal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005642-&&-annulate lamellae-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005049-&&-nuclear export signal receptor activity	G:9606:XPO1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A	XPO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO1	0.50947183	0.02703737	791	4	FALSE	XPO1	XPO1	86.03929024	0	790	0	0.83953049	FALSE	1	XPO1	24210800	0.01486315
792867	taxon:9606	1.94926737	0.02122132	181251	1902	estrogen receptor 1	gene	biological_process-&-1&-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060523-&&-prostate epithelial cord elongation-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0060068-&&-vagina development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032355-&&-response to estradiol-%%-GO:0060065-&&-uterus development-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0060745-&&-mammary gland branching involved in pregnancy-%%-GO:0007165-&&-signal transduction-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0043627-&&-response to estrogen-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008584-&&-male gonad development-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060750-&&-epithelial cell proliferation involved in mammary gland duct elongation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0001547-&&-antral ovarian follicle growth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002064-&&-epithelial cell development-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0005496-&&-steroid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0038052-&&-RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0034056-&&-estrogen response element binding	G:9606:ESR1	ESR1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	ESR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESR1	0.51301326	0.04158715	761	4	FALSE	ESR1	ESR1	104.9881423	0	760	0	0.84178877	FALSE	1	ESR1	25612074	0.01779449
787221	taxon:9606	1.98975894	0.01309663	179836	1902	minichromosome maintenance complex component 2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006260-&&-DNA replication-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0090102-&&-cochlea development-%%-GO:0006915-&&-apoptotic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0006268-&&-DNA unwinding involved in DNA replication|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0046872-&&-metal ion binding	G:9606:MCM2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM2	0.50257344	0.05185241	733	4	FALSE	MCM2	MCM2	114.0601915	0	732	0	0.83504018	FALSE	1	MCM2	19800226	0.02008994
788639	taxon:9606	1.95824799	0.01691253	177275	1902	ubiquitin C	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0019985-&&-translesion synthesis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010992-&&-ubiquitin homeostasis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0002020-&&-protease binding	G:9606:UBC			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	UBC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBC	0.51066055	0.04341534	694	3	FALSE	UBC	UBC	108.1921965	0	693	0	0.840292	FALSE	1	UBC	21519842	0.01828994
792994	taxon:9606	1.99621869	0.01457893	181025	1902	fibronectin 1	gene	biological_process-&-1&-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006953-&&-acute-phase response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2001202-&&-negative regulation of transforming growth factor-beta secretion-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:1904237-&&-positive regulation of substrate-dependent cell migration, cell attachment to substrate-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0007161-&&-calcium-independent cell-matrix adhesion-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0042060-&&-wound healing-%%-GO:0009611-&&-response to wounding-%%-GO:0033622-&&-integrin activation-%%-GO:0007155-&&-cell adhesion-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0001525-&&-angiogenesis-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005577-&&-fibrinogen complex-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005605-&&-basal lamina-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0002020-&&-protease binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0042802-&&-identical protein binding	G:9606:FN1	FN1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	FN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FN1	0.50094712	0.04784916	693	4	FALSE	FN1	FN1	108.4949349	0	692	0	0.83396355	FALSE	1	FN1	19796330	0.01910046
793224	taxon:9606	1.97290058	0.02972447	180501	1902	heat shock protein 90 alpha family class B member 1	gene	biological_process-&-1&-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:1903660-&&-negative regulation of complement-dependent cytotoxicity-%%-GO:0001890-&&-placenta development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:1905323-&&-telomerase holoenzyme complex assembly-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0042220-&&-response to cocaine-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0019062-&&-virion attachment to host cell-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0009651-&&-response to salt stress-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050821-&&-protein stabilization-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0045793-&&-positive regulation of cell size|cellular_component-&-1&-GO:0031526-&&-brush border membrane-%%-GO:1990917-&&-ooplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034751-&&-aryl hydrocarbon receptor complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0016234-&&-inclusion body-%%-GO:1990913-&&-sperm head plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032564-&&-dATP binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0030911-&&-TPR domain binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0002134-&&-UTP binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0017098-&&-sulfonylurea receptor binding-%%-GO:1990226-&&-histone methyltransferase binding-%%-GO:0002135-&&-CTP binding-%%-GO:0008144-&&-drug binding-%%-GO:0070182-&&-DNA polymerase binding	G:9606:HSP90AB1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSP90AB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90AB1	0.50686791	0.0328183	638	4	FALSE	HSP90AB1	HSP90AB1	98.59748428	0	637	0	0.8378499	FALSE	1	HSP90AB1	28407072	0.01686605
789863	taxon:9606	2.00740507	0.00997138	174485	1902	COP9 signalosome subunit 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1990182-&&-exosomal secretion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006413-&&-translational initiation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:1903894-&&-regulation of IRE1-mediated unfolded protein response-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0000338-&&-protein deneddylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:COPS5				COPS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS5	0.49815556	0.05883579	622	4	FALSE	COPS5	COPS5	114.2322581	0	621	0	0.83209915	FALSE	1	COPS5	14090880	0.02012733
792286	taxon:9606	2.03340161	0.00869935	182287	1902	cyclin dependent kinase 2	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0032298-&&-positive regulation of DNA-dependent DNA replication initiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051298-&&-centrosome duplication-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0006281-&&-DNA repair-%%-GO:0007099-&&-centriole replication-%%-GO:0010033-&&-response to organic substance-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0006813-&&-potassium ion transport-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0097124-&&-cyclin A2-CDK2 complex-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000806-&&-Y chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000805-&&-X chromosome-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005813-&&-centrosome-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0097134-&&-cyclin E1-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005768-&&-endosome-%%-GO:0097123-&&-cyclin A1-CDK2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0097135-&&-cyclin E2-CDK2 complex|molecular_function-&-1&-GO:0035173-&&-histone kinase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0097472-&&-cyclin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CDK2	CDK2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04934-&&-Cushing syndrome-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05226-&&-Gastric cancer	CDK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK2	0.49178677	0.05381297	610	4	FALSE	CDK2	CDK2	117.1694079	0	609	0	0.8277664	FALSE	1	CDK2	13324058	0.02119827
787370	taxon:9606	2.02410588	0.01566505	179545	1902	v-myc avian myelocytomatosis viral oncogene homolog	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0035690-&&-cellular response to drug-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0045656-&&-negative regulation of monocyte differentiation-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0051276-&&-chromosome organization-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0090096-&&-positive regulation of metanephric cap mesenchymal cell proliferation-%%-GO:0070848-&&-response to growth factor-%%-GO:0015671-&&-oxygen transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0032204-&&-regulation of telomere maintenance-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0044346-&&-fibroblast apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:MYC	MYC	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	MYC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYC	0.4940453	0.02822911	595	3	FALSE	MYC	MYC	89.98650927	0	594	0	0.82931569	FALSE	1	MYC	17925904	0.01614099
788021	taxon:9606	2.07042697	0.00678875	178372	1902	ring finger protein 2	gene	biological_process-&-1&-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0036353-&&-histone H2A-K119 monoubiquitination-%%-GO:0007281-&&-germ cell development-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0001739-&&-sex chromatin-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0000791-&&-euchromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0071535-&&-RING-like zinc finger domain binding	G:9606:RNF2				RNF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF2	0.48299216	0.04854765	584	4	FALSE	RNF2	RNF2	106.7353952	0	583	0	0.8215955	FALSE	1	RNF2	10919190	0.02008689
789554	taxon:9606	2.04789664	0.00422203	175192	1902	cullin 7	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0016032-&&-viral process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0007030-&&-Golgi organization-%%-GO:0006508-&&-proteolysis-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0001890-&&-placenta development|cellular_component-&-1&-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:1990393-&&-3M complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL7			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	CUL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL7	0.48830589	0.05826052	576	4	FALSE	CUL7	CUL7	118.8954704	0	575	0	0.82535056	FALSE	1	CUL7	8599358	0.02172766
788934	taxon:9606	2.05057507	0.00635927	176565	1902	cullin 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04350-&&-TGF-beta signaling pathway	CUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL1	0.48766808	0.07164612	561	4	FALSE	CUL1	CUL1	122.7245081	0	560	0	0.82490415	FALSE	1	CUL1	10195534	0.02244725
793024	taxon:9606	2.00740507	0.01495498	180878	1902	growth factor receptor bound protein 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0061024-&&-membrane organization-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0031623-&&-receptor internalization-%%-GO:0016032-&&-viral process-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0016477-&&-cell migration-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007411-&&-axon guidance-%%-GO:0007568-&&-aging-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070436-&&-Grb2-EGFR complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding	G:9606:GRB2	GRB2	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRB2	0.49815556	0.04135699	560	4	FALSE	GRB2	GRB2	100.8154122	0	559	0	0.83209915	FALSE	1	GRB2	18156750	0.01756485
790906	taxon:9606	2.10225303	0.00506524	170724	1902	sirtuin 7	gene	biological_process-&-1&-GO:0070932-&&-histone H3 deacetylation-%%-GO:0007072-&&-positive regulation of transcription involved in exit from mitosis-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0009303-&&-rRNA transcription-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005731-&&-nucleolus organizer region|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0097372-&&-NAD-dependent histone deacetylase activity (H3-K18 specific)-%%-GO:0070403-&&-NAD+ binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:SIRT7				SIRT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT7	0.47568013	0.04423982	558	4	FALSE	SIRT7	SIRT7	103.3655914	0	558	0	0.81629116	FALSE	0	SIRT7	8725136	0.02011186
791211	taxon:9606	2.09973216	0.00414973	169720	1902	cullin associated and neddylation dissociated 1	gene	biological_process-&-1&-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:CAND1				CAND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAND1	0.47625122	0.07924397	538	4	FALSE	CAND1	CAND1	118.6641791	0	537	0	0.81671131	FALSE	1	CAND1	7193154	0.02290706
790256	taxon:9606	2.08429179	0.0038304	173499	1902	obscurin like 1	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0071688-&&-striated muscle myosin thick filament assembly-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0007030-&&-Golgi organization-%%-GO:0045214-&&-sarcomere organization-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0007015-&&-actin filament organization-%%-GO:0055003-&&-cardiac myofibril assembly|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031430-&&-M band-%%-GO:1990393-&&-3M complex-%%-GO:0014704-&&-intercalated disc-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005859-&&-muscle myosin complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0051371-&&-muscle alpha-actinin binding	G:9606:OBSL1	OBSL1	TRUE		OBSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OBSL1	0.47977927	0.05768355	520	4	FALSE	OBSL1	OBSL1	115.9189189	0	519	0	0.8192847	FALSE	1	OBSL1	7260700	0.0218738
787636	taxon:9606	2.01118639	0.00589696	179048	1902	nucleophosmin	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032071-&&-regulation of endodeoxyribonuclease activity-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0007569-&&-cell aging-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007098-&&-centrosome cycle-%%-GO:0016032-&&-viral process-%%-GO:0008104-&&-protein localization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0042255-&&-ribosome assembly-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:0060699-&&-regulation of endoribonuclease activity-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0060735-&&-regulation of eIF2 alpha phosphorylation by dsRNA-%%-GO:0010826-&&-negative regulation of centrosome duplication-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0007165-&&-signal transduction-%%-GO:0051259-&&-protein oligomerization-%%-GO:1902751-&&-positive regulation of cell cycle G2/M phase transition-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006950-&&-response to stress-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0031616-&&-spindle pole centrosome-%%-GO:0005813-&&-centrosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042393-&&-histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:NPM1				NPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPM1	0.49721896	0.09448746	512	4	FALSE	NPM1	NPM1	148.9254902	0	511	0	0.83146894	FALSE	1	NPM1	10189322	0.0258234
788904	taxon:9606	1.99873956	0.00797541	176646	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0090168-&&-Golgi reassembly-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019901-&&-protein kinase binding	G:9606:YWHAZ			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAZ	0.50031531	0.07006433	512	4	FALSE	YWHAZ	YWHAZ	137.6254902	0	511	0	0.83354341	FALSE	1	YWHAZ	12552002	0.02355626
787251	taxon:9606	2.08366157	0.00456897	179797	1902	integrin subunit alpha 4	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:1990771-&&-clathrin-dependent extracellular exosome endocytosis-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0098657-&&-import into cell-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0003366-&&-cell-matrix adhesion involved in ameboidal cell migration-%%-GO:0030183-&&-B cell differentiation-%%-GO:0050904-&&-diapedesis-%%-GO:1903238-&&-positive regulation of leukocyte tethering or rolling-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0050776-&&-regulation of immune response-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0090074-&&-negative regulation of protein homodimerization activity-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0043113-&&-receptor clustering|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034669-&&-integrin alpha4-beta7 complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0046872-&&-metal ion binding-%%-GO:1990405-&&-protein antigen binding-%%-GO:0019960-&&-C-X3-C chemokine binding	G:9606:ITGA4			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05140-&&-Leishmaniasis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA4	0.47992439	0.06555813	504	4	FALSE	ITGA4	ITGA4	125.2948207	0	503	0	0.81938974	FALSE	1	ITGA4	9035276	0.02355571
788860	taxon:9606	2.00047266	0.00831711	176743	1902	valosin containing protein	gene	biological_process-&-1&-GO:0034214-&&-protein hexamerization-%%-GO:0036503-&&-ERAD pathway-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006734-&&-NADH metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1903007-&&-positive regulation of Lys63-specific deubiquitinase activity-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070842-&&-aggresome assembly-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903006-&&-positive regulation of protein K63-linked deubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:1903862-&&-positive regulation of oxidative phosphorylation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:2000158-&&-positive regulation of ubiquitin-specific protease activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0010918-&&-positive regulation of mitochondrial membrane potential-%%-GO:0019079-&&-viral genome replication-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0072389-&&-flavin adenine dinucleotide catabolic process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006479-&&-protein methylation-%%-GO:0006457-&&-protein folding-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:1903715-&&-regulation of aerobic respiration|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990730-&&-VCP-NSFL1C complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0035800-&&-deubiquitinase activator activity-%%-GO:1904288-&&-BAT3 complex binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043531-&&-ADP binding-%%-GO:0044389-&&-ubiquitin-like protein ligase binding-%%-GO:1990381-&&-ubiquitin-specific protease binding	G:9606:VCP			KEGG-&-1&-hsa05134-&&-Legionellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	VCP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCP	0.49988186	0.05444826	488	4	FALSE	VCP	VCP	124.9032922	0	487	0	0.83325456	FALSE	1	VCP	11514990	0.02132477
791705	taxon:9606	2.08507957	0.00481407	167303	1902	coiled-coil domain containing 8	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0010923-&&-negative regulation of phosphatase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:1990393-&&-3M complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC8				CCDC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC8	0.47959801	0.04632229	474	4	FALSE	CCDC8	CCDC8	112.9724576	0	473	0	0.81915341	FALSE	1	CCDC8	7780660	0.02118088
792825	taxon:9606	2.05829526	0.00719502	181302	1902	E1A binding protein p300	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0007507-&&-heart development-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0090043-&&-regulation of tubulin deacetylation-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0007399-&&-nervous system development-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006473-&&-protein acetylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007623-&&-circadian rhythm-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0030324-&&-lung development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0001756-&&-somitogenesis-%%-GO:0043627-&&-response to estrogen-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0030220-&&-platelet formation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030183-&&-B cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043969-&&-histone H2B acetylation-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0034212-&&-peptide N-acetyltransferase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0016746-&&-transferase activity, transferring acyl groups-%%-GO:0061733-&&-peptide-lysine-N-acetyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004468-&&-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:EP300			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04916-&&-Melanogenesis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	EP300	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EP300	0.48583895	0.06768845	458	4	FALSE	EP300	EP300	119.2938597	0	457	0	0.82361746	FALSE	1	EP300	10460294	0.02159516
790508	taxon:9606	2.11328187	0.00730992	172653	1902	F-box protein 6	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0006281-&&-DNA repair-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006516-&&-glycoprotein catabolic process|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:FBXO6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	FBXO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO6	0.47319764	0.04158473	456	4	FALSE	FBXO6	FBXO6	103.9210526	0	456	0	0.81445302	FALSE	0	FBXO6	9929286	0.02012599
792269	taxon:9606	2.10965811	0.00448305	182315	1902	cell division cycle 5 like	gene	biological_process-&-1&-GO:1904568-&&-cellular response to wortmannin-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0071352-&&-cellular response to interleukin-2-%%-GO:1990646-&&-cellular response to prolactin-%%-GO:0030154-&&-cell differentiation-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0072422-&&-signal transduction involved in DNA damage checkpoint|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0071987-&&-WD40-repeat domain binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001222-&&-transcription corepressor binding	G:9606:CDC5L			KEGG-&-1&-hsa03040-&&-Spliceosome	CDC5L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC5L	0.47401046	0.06277408	453	4	FALSE	CDC5L	CDC5L	116.0022173	0	452	0	0.81505698	FALSE	1	CDC5L	7024224	0.02228884
788855	taxon:9606	2.11139121	0.0039686	176745	1902	vascular cell adhesion molecule 1	gene	biological_process-&-1&-GO:0035094-&&-response to nicotine-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030183-&&-B cell differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0010043-&&-response to zinc ion-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0007568-&&-aging-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0045471-&&-response to ethanol-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0007584-&&-response to nutrient-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007155-&&-cell adhesion-%%-GO:0016032-&&-viral process-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0009308-&&-amine metabolic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005902-&&-microvillus-%%-GO:0071065-&&-alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0045177-&&-apical part of cell-%%-GO:0002102-&&-podosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0042383-&&-sarcolemma-%%-GO:0030175-&&-filopodium-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0008131-&&-primary amine oxidase activity-%%-GO:0005178-&&-integrin binding	G:9606:VCAM1	VCAM1	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria	VCAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCAM1	0.47362137	0.06407095	451	4	FALSE	VCAM1	VCAM1	123.2048998	0	450	0	0.81476813	FALSE	1	VCAM1	7743360	0.02373633
792049	taxon:9606	2.06979675	0.00703699	182690	1902	BRCA1, DNA repair associated	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0000732-&&-strand displacement-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046600-&&-negative regulation of centriole replication-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043009-&&-chordate embryonic development-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006915-&&-apoptotic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0070512-&&-positive regulation of histone H4-K20 methylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0043627-&&-response to estrogen-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0007098-&&-centrosome cycle-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2000620-&&-positive regulation of histone H4-K16 acetylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006260-&&-DNA replication-%%-GO:0009048-&&-dosage compensation by inactivation of X chromosome-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006301-&&-postreplication repair-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0031436-&&-BRCA1-BARD1 complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0043234-&&-protein complex-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:BRCA1	BRCA1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance	BRCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRCA1	0.48313923	0.05339105	443	4	FALSE	BRCA1	BRCA1	115.2018141	0	442	0	0.82170054	FALSE	1	BRCA1	9580640	0.02111746
788723	taxon:9606	2.06680321	0.00604678	177116	1902	TNF receptor associated factor 6	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048468-&&-cell development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045453-&&-bone resorption-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001503-&&-ossification-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007254-&&-JNK cascade-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005811-&&-lipid particle-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding	G:9606:TRAF6			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05162-&&-Measles-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05133-&&-Pertussis	TRAF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF6	0.483839	0.04175255	433	4	FALSE	TRAF6	TRAF6	102.2111369	0	432	0	0.82219946	FALSE	1	TRAF6	8213850	0.01862236
793307	taxon:9606	2.11533008	0.00504046	180336	1902	histone deacetylase 1	gene	biological_process-&-1&-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007596-&&-blood coagulation-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016575-&&-histone deacetylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042733-&&-embryonic digit morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HDAC1			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis	HDAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC1	0.47273946	0.07049648	431	4	FALSE	HDAC1	HDAC1	110.004662	0	430	0	0.81411165	FALSE	1	HDAC1	7640574	0.02120915
787026	taxon:9606	2.07988026	0.00361884	180209	1902	heterogeneous nuclear ribonucleoprotein U	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding	G:9606:HNRNPU			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPU	0.48079691	0.1158996	430	4	FALSE	HNRNPU	HNRNPU	144.4953488	0	430	0	0.82001996	FALSE	0	HNRNPU	6032744	0.02670271
790146	taxon:9606	2.08413424	0.00431951	173778	1902	SNW domain containing 1	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0070564-&&-positive regulation of vitamin D receptor signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0000350-&&-generation of catalytic spliceosome for second transesterification step-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0048385-&&-regulation of retinoic acid receptor signaling pathway-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0016032-&&-viral process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway|cellular_component-&-1&-GO:0071014-&&-post-mRNA release spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0071146-&&-SMAD3-SMAD4 protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005112-&&-Notch binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity	G:9606:SNW1			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03040-&&-Spliceosome	SNW1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNW1	0.47981554	0.062816	430	4	FALSE	SNW1	SNW1	120.161215	0	429	0	0.81931096	FALSE	1	SNW1	6776840	0.02229206
789279	taxon:9606	2.16606271	0.0027274	175838	1902	embryonic ectoderm development	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0021510-&&-spinal cord development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000011-&&-regulation of adaxial/abaxial pattern formation-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0016571-&&-histone methylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0001739-&&-sex chromatin-%%-GO:0045120-&&-pronucleus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042054-&&-histone methyltransferase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:EED				EED	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EED	0.46166715	0.07838391	422	4	FALSE	EED	EED	123.2619048	0	421	0	0.80565622	FALSE	1	EED	5034808	0.02525615
792883	taxon:9606	2.06491256	0.0061456	181227	1902	EWS RNA binding protein 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042802-&&-identical protein binding	G:9606:EWSR1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	EWSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EWSR1	0.48428201	0.05190871	420	4	FALSE	EWSR1	EWSR1	121.5909091	0	419	0	0.82251457	FALSE	1	EWSR1	8510660	0.0220487
793220	taxon:9606	2.06081613	0.01794271	180508	1902	heat shock protein family B (small) member 1	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0009615-&&-response to virus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0099641-&&-anterograde axonal protein transport-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005819-&&-spindle-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0042802-&&-identical protein binding	G:9606:HSPB1	HSPB1	TRUE	KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04370-&&-VEGF signaling pathway	HSPB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB1	0.48524465	0.03335762	415	4	FALSE	HSPB1	HSPB1	100.7336562	0	414	0	0.82319731	FALSE	1	HSPB1	16338862	0.01829853
789529	taxon:9606	2.06822121	0.00382251	175255	1902	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006284-&&-base-excision repair-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0030154-&&-cell differentiation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:HUWE1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HUWE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HUWE1	0.48350728	0.07221826	406	4	FALSE	HUWE1	HUWE1	135.8069307	0	405	0	0.82196313	FALSE	1	HUWE1	6268754	0.02463349
793359	taxon:9606	2.06333701	0.00354736	180243	1902	heterogeneous nuclear ribonucleoprotein A1	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0051168-&&-nuclear export-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0061752-&&-telomeric repeat-containing RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:HNRNPA1			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA1	0.4846518	0.0994194	401	4	FALSE	HNRNPA1	HNRNPA1	145.3433584	0	400	0	0.82277717	FALSE	1	HNRNPA1	5850656	0.02619226
788820	taxon:9606	2.08051048	0.00558991	176809	1902	ubiquitin conjugating enzyme E2 I	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:1903755-&&-positive regulation of SUMO transferase activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:1990356-&&-sumoylated E2 ligase complex-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:1990234-&&-transferase complex|molecular_function-&-1&-GO:0043398-&&-HLH domain binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0071535-&&-RING-like zinc finger domain binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0061656-&&-SUMO conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2I			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa03013-&&-RNA transport-%%-hsa04064-&&-NF-kappa B signaling pathway	UBE2I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2I	0.48065127	0.05072241	398	4	FALSE	UBE2I	UBE2I	109.9419192	0	397	0	0.81991492	FALSE	1	UBE2I	7712652	0.02020341
787446	taxon:9606	2.0630219	0.0059196	179422	1902	MDM2 proto-oncogene	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0045472-&&-response to ether-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007089-&&-traversing start control point of mitotic cell cycle-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0016925-&&-protein sumoylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0016032-&&-viral process-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0042493-&&-response to drug-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0036369-&&-transcription factor catabolic process-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:1901797-&&-negative regulation of signal transduction by p53 class mediator-%%-GO:0003283-&&-atrial septum development-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042220-&&-response to cocaine-%%-GO:1990785-&&-response to water-immersion restraint stress-%%-GO:0009636-&&-response to toxic substance-%%-GO:0043278-&&-response to morphine-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0010039-&&-response to iron ion-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1904404-&&-response to formaldehyde-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0071494-&&-cellular response to UV-C-%%-GO:0001568-&&-blood vessel development-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0031648-&&-protein destabilization-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0071301-&&-cellular response to vitamin B1-%%-GO:0018205-&&-peptidyl-lysine modification-%%-GO:0003281-&&-ventricular septum development-%%-GO:0034504-&&-protein localization to nucleus|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0016874-&&-ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0002039-&&-p53 binding	G:9606:MDM2	MDM2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance	MDM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDM2	0.48472583	0.05346108	395	4	FALSE	MDM2	MDM2	118.3638677	0	394	0	0.82282968	FALSE	1	MDM2	7776468	0.02131547
788865	taxon:9606	2.10398614	0.00496704	176732	1902	von Hippel-Lindau tumor suppressor	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006508-&&-proteolysis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045597-&&-positive regulation of cell differentiation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030891-&&-VCB complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:VHL			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	VHL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VHL	0.4752883	0.05061993	385	4	FALSE	VHL	VHL	116.9373368	0	384	0	0.81600231	FALSE	1	VHL	7165050	0.02206754
788040	taxon:9606	2.09831416	0.00254774	178319	1902	replication protein A1	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006260-&&-DNA replication-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006284-&&-base-excision repair-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0034502-&&-protein localization to chromosome-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006310-&&-DNA recombination-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006298-&&-mismatch repair-%%-GO:0006281-&&-DNA repair-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000723-&&-telomere maintenance-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:RPA1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa03460-&&-Fanconi anemia pathway	RPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA1	0.47657306	0.07354076	380	4	FALSE	RPA1	RPA1	127.8492064	0	379	0	0.81694764	FALSE	1	RPA1	4923716	0.02388812
789125	taxon:9606	2.17000158	0.00118483	176149	1902	histone cluster 1 H3 family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3F			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3F	0.46082916	0.11497872	378	4	FALSE	HIST1H3F	HIST1H3F	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3F	4593174	0.02554688
789187	taxon:9606	2.17000158	0.00118483	176033	1902	histone cluster 1 H3 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3A	0.46082916	0.11497872	378	4	FALSE	HIST1H3A	HIST1H3A	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3A	4593174	0.02554688
789188	taxon:9606	2.17000158	0.00118483	176032	1902	histone cluster 1 H3 family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3D			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3D	0.46082916	0.11497872	378	4	FALSE	HIST1H3D	HIST1H3D	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3D	4593174	0.02554688
789191	taxon:9606	2.17000158	0.00118483	176029	1902	histone cluster 1 H3 family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3I			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3I	0.46082916	0.11497872	378	4	FALSE	HIST1H3I	HIST1H3I	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3I	4593174	0.02554688
789192	taxon:9606	2.17000158	0.00118483	176028	1902	histone cluster 1 H3 family member g	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3G			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3G	0.46082916	0.11497872	378	4	FALSE	HIST1H3G	HIST1H3G	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3G	4593174	0.02554688
789193	taxon:9606	2.17000158	0.00118483	176031	1902	histone cluster 1 H3 family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3C	0.46082916	0.11497872	378	4	FALSE	HIST1H3C	HIST1H3C	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3C	4593174	0.02554688
789194	taxon:9606	2.17000158	0.00118483	176030	1902	histone cluster 1 H3 family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3E			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3E	0.46082916	0.11497872	378	4	FALSE	HIST1H3E	HIST1H3E	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3E	4593174	0.02554688
789195	taxon:9606	2.17000158	0.00118483	176025	1902	histone cluster 1 H3 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3B			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3B	0.46082916	0.11497872	378	4	FALSE	HIST1H3B	HIST1H3B	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3B	4593174	0.02554688
789197	taxon:9606	2.17000158	0.00118483	176027	1902	histone cluster 1 H3 family member j	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3J			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3J	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3J	0.46082916	0.11497872	378	4	FALSE	HIST1H3J	HIST1H3J	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3J	4593174	0.02554688
789198	taxon:9606	2.17000158	0.00118483	176026	1902	histone cluster 1 H3 family member h	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0060968-&&-regulation of gene silencing-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0045296-&&-cadherin binding	G:9606:HIST1H3H			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST1H3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H3H	0.46082916	0.11497872	378	4	FALSE	HIST1H3H	HIST1H3H	125.2819149	0	377	0	0.80499974	FALSE	1	HIST1H3H	4593174	0.02554688
789859	taxon:9606	2.07861982	0.00371794	174499	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006605-&&-protein targeting-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034766-&&-negative regulation of ion transmembrane transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:YWHAQ			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAQ	0.48108846	0.0649697	377	4	FALSE	YWHAQ	YWHAQ	129.9413333	0	376	0	0.82023003	FALSE	1	YWHAQ	6274272	0.02372009
787956	taxon:9606	2.11044588	0.00340154	178512	1902	parkin RBR E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0033132-&&-negative regulation of glucokinase activity-%%-GO:0042053-&&-regulation of dopamine metabolic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:1903202-&&-negative regulation of oxidative stress-induced cell death-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0099074-&&-mitochondrion to lysosome transport-%%-GO:1900407-&&-regulation of cellular response to oxidative stress-%%-GO:0051582-&&-positive regulation of neurotransmitter uptake-%%-GO:0007417-&&-central nervous system development-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0000422-&&-mitophagy-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0010636-&&-positive regulation of mitochondrial fusion-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0036503-&&-ERAD pathway-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0000423-&&-macromitophagy-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:1905366-&&-negative regulation of intralumenal vesicle formation-%%-GO:0010637-&&-negative regulation of mitochondrial fusion-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:1903378-&&-positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:1905281-&&-positive regulation of retrograde transport, endosome to Golgi-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1902254-&&-negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0016236-&&-macroautophagy-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0031648-&&-protein destabilization-%%-GO:0055069-&&-zinc ion homeostasis-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0070050-&&-neuron cellular homeostasis-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0044314-&&-protein K27-linked ubiquitination-%%-GO:0032368-&&-regulation of lipid transport-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0070842-&&-aggresome assembly-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:1902283-&&-negative regulation of primary amine oxidase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:1902803-&&-regulation of synaptic vesicle transport-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:1905477-&&-positive regulation of protein localization to membrane-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0007612-&&-learning-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:0050821-&&-protein stabilization-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0034620-&&-cellular response to unfolded protein-%%-GO:0001964-&&-startle response-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:1902530-&&-positive regulation of protein linear polyubiquitination-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1903542-&&-negative regulation of exosomal secretion-%%-GO:0035519-&&-protein K29-linked ubiquitination-%%-GO:0097237-&&-cellular response to toxic substance-%%-GO:1904049-&&-negative regulation of spontaneous neurotransmitter secretion-%%-GO:0042415-&&-norepinephrine metabolic process-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1903382-&&-negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0097413-&&-Lewy body-%%-GO:0016235-&&-aggresome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0099073-&&-mitochondrion-derived vesicle-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0071797-&&-LUBAC complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043005-&&-neuron projection-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019900-&&-kinase binding-%%-GO:1990444-&&-F-box domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0030544-&&-Hsp70 protein binding	G:9606:PARK2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	PARK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARK2	0.47383352	0.05845868	374	4	FALSE	PARK2	PARK2	119.7526882	0	373	0	0.81492569	FALSE	1	PARK2	5382296	0.02269836
793221	taxon:9606	2.02016701	0.00531196	180511	1902	heat shock protein family A (Hsp70) member 8	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0061738-&&-late endosomal microautophagy-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:1902904-&&-negative regulation of supramolecular fiber organization-%%-GO:0006457-&&-protein folding-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1904589-&&-regulation of protein import-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0061635-&&-regulation of protein complex stability-%%-GO:0061741-&&-chaperone-mediated protein transport involved in chaperone-mediated autophagy-%%-GO:0061740-&&-protein targeting to lysosome involved in chaperone-mediated autophagy-%%-GO:1904764-&&-chaperone-mediated autophagy translocation complex disassembly-%%-GO:0072318-&&-clathrin coat disassembly-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0061684-&&-chaperone-mediated autophagy-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0042026-&&-protein refolding-%%-GO:0006479-&&-protein methylation-%%-GO:0061024-&&-membrane organization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005770-&&-late endosome-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0000974-&&-Prp19 complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0098575-&&-lumenal side of lysosomal membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:HSPA8			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04144-&&-Endocytosis-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05134-&&-Legionellosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA8	0.49500858	0.08165282	368	4	FALSE	HSPA8	HSPA8	156.1830601	0	367	0	0.82997217	FALSE	1	HSPA8	8519904	0.02668381
788041	taxon:9606	2.09579329	0.00277244	178318	1902	replication protein A2	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0006284-&&-base-excision repair-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006298-&&-mismatch repair-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000723-&&-telomere maintenance-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0034502-&&-protein localization to chromosome-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0000785-&&-chromatin-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:RPA2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa03460-&&-Fanconi anemia pathway	RPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA2	0.47714629	0.06481382	362	4	FALSE	RPA2	RPA2	121.198895	0	362	0	0.81736779	FALSE	0	RPA2	4894372	0.02253503
788936	taxon:9606	2.14116906	0.0023183	176566	1902	cullin 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0030891-&&-VCB complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:CUL2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	CUL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL2	0.46703458	0.0855729	359	4	FALSE	CUL2	CUL2	132.3008357	0	359	0	0.80980516	FALSE	0	CUL2	4248806	0.02596807
788541	taxon:9606	2.0595557	0.00614214	177469	1902	SRC proto-oncogene, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0048477-&&-oogenesis-%%-GO:0086098-&&-angiotensin-activated signaling pathway involved in heart process-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0007172-&&-signal complex assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0060491-&&-regulation of cell projection assembly-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0071393-&&-cellular response to progesterone stimulus-%%-GO:0033625-&&-positive regulation of integrin activation-%%-GO:0007165-&&-signal transduction-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0022407-&&-regulation of cell-cell adhesion-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007417-&&-central nervous system development-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0051057-&&-positive regulation of small GTPase mediated signal transduction-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0010954-&&-positive regulation of protein processing-%%-GO:0045056-&&-transcytosis-%%-GO:2001286-&&-regulation of caveolin-mediated endocytosis-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0045453-&&-bone resorption-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0060065-&&-uterus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0030900-&&-forebrain development-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0034332-&&-adherens junction organization-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0007049-&&-cell cycle-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0051385-&&-response to mineralocorticoid-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0010447-&&-response to acidic pH-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0031648-&&-protein destabilization-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007411-&&-axon guidance-%%-GO:0010641-&&-positive regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051902-&&-negative regulation of mitochondrial depolarization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0009615-&&-response to virus-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0036035-&&-osteoclast development-%%-GO:0045087-&&-innate immune response-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005770-&&-late endosome-%%-GO:0005884-&&-actin filament-%%-GO:0005764-&&-lysosome-%%-GO:0002102-&&-podosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0032587-&&-ruffle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0016301-&&-kinase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0019900-&&-kinase binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0051427-&&-hormone receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005178-&&-integrin binding-%%-GO:0020037-&&-heme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SRC			KEGG-&-1&-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05152-&&-Tuberculosis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa04727-&&-GABAergic synapse-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa04540-&&-Gap junction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04915-&&-Estrogen signaling pathway	SRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRC	0.48554162	0.05550699	354	4	FALSE	SRC	SRC	102.8551136	0	353	0	0.82340738	FALSE	1	SRC	7375422	0.01831589
789634	taxon:9606	2.13675752	0.00191789	175023	1902	histone deacetylase 5	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0030182-&&-neuron differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0042113-&&-B cell activation-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0006325-&&-chromatin organization-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006954-&&-inflammatory response-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006476-&&-protein deacetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006342-&&-chromatin silencing-%%-GO:0010830-&&-regulation of myotube differentiation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001025-&&-RNA polymerase III transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003682-&&-chromatin binding	G:9606:HDAC5			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	HDAC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC5	0.46799882	0.08125356	353	4	FALSE	HDAC5	HDAC5	146.4188034	0	352	0	0.81054041	FALSE	1	HDAC5	4086100	0.02850223
792630	taxon:9606	2.07011186	0.00446541	181687	1902	eukaryotic translation elongation factor 1 alpha 1	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0006479-&&-protein methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0098574-&&-cytoplasmic side of lysosomal membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003746-&&-translation elongation factor activity	G:9606:EEF1A1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05134-&&-Legionellosis	EEF1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1A1	0.48306568	0.09604585	352	4	FALSE	EEF1A1	EEF1A1	158.1085714	0	351	0	0.82164802	FALSE	1	EEF1A1	6741606	0.02848033
792170	taxon:9606	2.07861982	0.00666879	182481	1902	androgen receptor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007548-&&-sex differentiation-%%-GO:0048638-&&-regulation of developmental growth-%%-GO:0060599-&&-lateral sprouting involved in mammary gland duct morphogenesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030850-&&-prostate gland development-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0060748-&&-tertiary branching involved in mammary gland duct morphogenesis-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060520-&&-activation of prostate induction by androgen receptor signaling pathway-%%-GO:0060571-&&-morphogenesis of an epithelial fold-%%-GO:0060769-&&-positive regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0016049-&&-cell growth-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0048645-&&-animal organ formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003073-&&-regulation of systemic arterial blood pressure-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0007338-&&-single fertilization-%%-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0019102-&&-male somatic sex determination-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0051259-&&-protein oligomerization-%%-GO:0060742-&&-epithelial cell differentiation involved in prostate gland development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0060736-&&-prostate gland growth-%%-GO:0006810-&&-transport-%%-GO:0045720-&&-negative regulation of integrin biosynthetic process-%%-GO:0048808-&&-male genitalia morphogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090003-&&-regulation of establishment of protein localization to plasma membrane-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045726-&&-positive regulation of integrin biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004882-&&-androgen receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005497-&&-androgen binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0070974-&&-POU domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0051117-&&-ATPase binding	G:9606:AR	AR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05200-&&-Pathways in cancer	AR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AR	0.48108846	0.05288494	346	4	FALSE	AR	AR	109.6715116	0	345	0	0.82023003	FALSE	1	AR	7476992	0.01993137
791918	taxon:9606	2.0679061	0.00807408	182878	1902	AKT serine/threonine kinase 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0035655-&&-interleukin-18-mediated signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0001893-&&-maternal placenta development-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0006954-&&-inflammatory response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1901976-&&-regulation of cell cycle checkpoint-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0100002-&&-negative regulation of protein kinase activity by protein phosphorylation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0031929-&&-TOR signaling-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0030168-&&-platelet activation-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0015758-&&-glucose transport-%%-GO:0007165-&&-signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060709-&&-glycogen cell differentiation involved in embryonic placenta development-%%-GO:0030030-&&-cell projection organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0031999-&&-negative regulation of fatty acid beta-oxidation-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016310-&&-phosphorylation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:0009408-&&-response to heat-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0061024-&&-membrane organization-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0043276-&&-anoikis-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0007281-&&-germ cell development-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0031641-&&-regulation of myelination-%%-GO:0021510-&&-spinal cord development-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070141-&&-response to UV-A-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010975-&&-regulation of neuron projection development-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006417-&&-regulation of translation-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:1990418-&&-response to insulin-like growth factor stimulus-%%-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0046622-&&-positive regulation of organ growth-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0007568-&&-aging-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0006412-&&-translation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0072656-&&-maintenance of protein location in mitochondrion-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0060416-&&-response to growth hormone-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0030163-&&-protein catabolic process-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0032094-&&-response to food-%%-GO:0031295-&&-T cell costimulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005819-&&-spindle-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0030235-&&-nitric-oxide synthase regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0004672-&&-protein kinase activity	G:9606:AKT1	AKT1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	AKT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT1	0.48358095	0.04377514	337	4	FALSE	AKT1	AKT1	104.5492537	0	336	0	0.82201565	FALSE	1	AKT1	8275776	0.01877053
788990	taxon:9606	2.16637782	0.00216558	176447	1902	cullin 5	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0008283-&&-cell proliferation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:CUL5			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CUL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL5	0.4616	0.09838751	332	4	FALSE	CUL5	CUL5	133.8614458	0	332	0	0.8056037	FALSE	0	CUL5	3822434	0.02694834
789203	taxon:9606	2.09248464	0.00435226	176012	1902	inhibitor of nuclear factor kappa B kinase subunit gamma	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043276-&&-anoikis-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0051650-&&-establishment of vesicle localization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1990450-&&-linear polyubiquitin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding	G:9606:IKBKG			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	IKBKG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKG	0.47790076	0.05250575	331	4	FALSE	IKBKG	IKBKG	110.0212766	0	330	0	0.81791923	FALSE	1	IKBKG	5454878	0.02027426
788898	taxon:9606	2.08665511	0.00288582	176648	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006605-&&-protein targeting-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:YWHAG			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAG	0.47923588	0.07710925	329	4	FALSE	YWHAG	YWHAG	140.3333333	0	328	0	0.81889081	FALSE	1	YWHAG	5130778	0.02564928
792385	taxon:9606	2.15377344	0.00343522	182109	1902	CREB binding protein	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006473-&&-protein acetylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0016573-&&-histone acetylation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042592-&&-homeostatic process-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0048511-&&-rhythmic process-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042733-&&-embryonic digit morphogenesis|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043426-&&-MRF binding-%%-GO:0034212-&&-peptide N-acetyltransferase activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding	G:9606:CREBBP			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04916-&&-Melanogenesis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	CREBBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREBBP	0.46430139	0.08134853	327	4	FALSE	CREBBP	CREBBP	118.6	0	326	0	0.80770443	FALSE	1	CREBBP	5342088	0.02347928
788897	taxon:9606	2.08381913	0.00351283	176649	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:1902309-&&-negative regulation of peptidyl-serine dephosphorylation-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0061024-&&-membrane organization-%%-GO:0003064-&&-regulation of heart rate by hormone-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006605-&&-protein targeting-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016032-&&-viral process-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0021762-&&-substantia nigra development-%%-GO:0035329-&&-hippo signaling-%%-GO:0034605-&&-cellular response to heat-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005871-&&-kinesin complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0019899-&&-enzyme binding	G:9606:YWHAE			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAE	0.4798881	0.08150824	326	4	FALSE	YWHAE	YWHAE	146.8858025	0	325	0	0.81936348	FALSE	1	YWHAE	5799948	0.0267486
789491	taxon:9606	2.17047424	0.00256209	175350	1902	inhibitor of nuclear factor kappa B kinase subunit epsilon	gene	biological_process-&-1&-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0006955-&&-immune response-%%-GO:0098586-&&-cellular response to virus-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034340-&&-response to type I interferon-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0031966-&&-mitochondrial membrane-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:IKBKE			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	IKBKE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKE	0.4607288	0.03879525	326	4	FALSE	IKBKE	IKBKE	101.9197531	0	325	0	0.80492096	FALSE	1	IKBKE	3918372	0.02061943
792445	taxon:9606	2.04773909	0.00430342	182011	1902	catenin beta 1	gene	biological_process-&-1&-GO:0090279-&&-regulation of calcium ion import-%%-GO:1904793-&&-regulation of euchromatin binding-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0060916-&&-mesenchymal cell proliferation involved in lung development-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0003266-&&-regulation of secondary heart field cardioblast proliferation-%%-GO:0061550-&&-cranial ganglion development-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0035315-&&-hair cell differentiation-%%-GO:0060066-&&-oviduct development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:0001708-&&-cell fate specification-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060769-&&-positive regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048538-&&-thymus development-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0045453-&&-bone resorption-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0050808-&&-synapse organization-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0070602-&&-regulation of centromeric sister chromatid cohesion-%%-GO:0045603-&&-positive regulation of endothelial cell differentiation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0034333-&&-adherens junction assembly-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0044334-&&-canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0022009-&&-central nervous system vasculogenesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0072053-&&-renal inner medulla development-%%-GO:0044336-&&-canonical Wnt signaling pathway involved in negative regulation of apoptotic process-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0060479-&&-lung cell differentiation-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0048469-&&-cell maturation-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0000578-&&-embryonic axis specification-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0048599-&&-oocyte development-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:1904501-&&-positive regulation of chromatin-mediated maintenance of transcription-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:1990791-&&-dorsal root ganglion development-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0003338-&&-metanephros morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0060492-&&-lung induction-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0010909-&&-positive regulation of heparan sulfate proteoglycan biosynthetic process-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0060742-&&-epithelial cell differentiation involved in prostate gland development-%%-GO:0072054-&&-renal outer medulla development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:1904798-&&-positive regulation of core promoter binding-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0007403-&&-glial cell fate determination-%%-GO:0060440-&&-trachea formation-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0045743-&&-positive regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0030997-&&-regulation of centriole-centriole cohesion-%%-GO:0003340-&&-negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0009950-&&-dorsal/ventral axis specification-%%-GO:0030539-&&-male genitalia development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0045976-&&-negative regulation of mitotic cell cycle, embryonic-%%-GO:0035112-&&-genitalia morphogenesis-%%-GO:0072033-&&-renal vesicle formation-%%-GO:0032355-&&-response to estradiol-%%-GO:0036023-&&-embryonic skeletal limb joint morphogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0048145-&&-regulation of fibroblast proliferation-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0035411-&&-catenin import into nucleus-%%-GO:1904888-&&-cranial skeletal system development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0042493-&&-response to drug-%%-GO:0031016-&&-pancreas development-%%-GO:2000017-&&-positive regulation of determination of dorsal identity-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0007398-&&-ectoderm development-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0061324-&&-canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:1990403-&&-embryonic brain development-%%-GO:0030902-&&-hindbrain development-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0001764-&&-neuron migration-%%-GO:0072079-&&-nephron tubule formation-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:1904954-&&-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0072182-&&-regulation of nephron tubule epithelial cell differentiation-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0031641-&&-regulation of myelination-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000904-&&-cell morphogenesis involved in differentiation-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0001840-&&-neural plate development|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005938-&&-cell cortex-%%-GO:0005912-&&-adherens junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0070369-&&-beta-catenin-TCF7L2 complex-%%-GO:0030054-&&-cell junction-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0016342-&&-catenin complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005916-&&-fascia adherens-%%-GO:0000922-&&-spindle pole-%%-GO:1990909-&&-Wnt signalosome-%%-GO:1990907-&&-beta-catenin-TCF complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016600-&&-flotillin complex-%%-GO:0005634-&&-nucleus-%%-GO:0031528-&&-microvillus membrane-%%-GO:0016020-&&-membrane-%%-GO:0034750-&&-Scrib-APC-beta-catenin complex-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0019900-&&-kinase binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding	G:9606:CTNNB1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05216-&&-Thyroid cancer-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CTNNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNB1	0.48834346	0.06591369	324	4	FALSE	CTNNB1	CTNNB1	138.9814815	0	324	0	0.82537682	FALSE	0	CTNNB1	6427824	0.02429692
787831	taxon:9606	2.08381913	0.00607484	178742	1902	mitogen-activated protein kinase 1	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0043627-&&-response to estrogen-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030278-&&-regulation of ossification-%%-GO:0016032-&&-viral process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0019858-&&-cytosine metabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048538-&&-thymus development-%%-GO:0030168-&&-platelet activation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0061308-&&-cardiac neural crest cell development involved in heart development-%%-GO:0035094-&&-response to nicotine-%%-GO:0009636-&&-response to toxic substance-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0007411-&&-axon guidance-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0006935-&&-chemotaxis-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0060440-&&-trachea formation-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0007611-&&-learning or memory-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0060324-&&-face development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007049-&&-cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045596-&&-negative regulation of cell differentiation|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031143-&&-pseudopodium-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0016301-&&-kinase activity	G:9606:MAPK1	MAPK1	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05132-&&-Salmonella infection-%%-hsa04720-&&-Long-term potentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05160-&&-Hepatitis C-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction	MAPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK1	0.4798881	0.04744938	323	4	FALSE	MAPK1	MAPK1	106.8722741	0	322	0	0.81936348	FALSE	1	MAPK1	7134482	0.01944857
789596	taxon:9606	2.2270364	0.00146933	175099	1902	PAN2 poly(A) specific ribonuclease subunit	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006397-&&-mRNA processing-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0031251-&&-PAN complex-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity-%%-GO:0005515-&&-protein binding	G:9606:PAN2			KEGG-&-1&-hsa03018-&&-RNA degradation	PAN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAN2	0.44902724	0.08060748	321	4	FALSE	PAN2	PAN2	122.0560748	0	321	0	0.79549393	FALSE	0	PAN2	2820500	0.02660437
789973	taxon:9606	2.15267055	0.00146476	174214	1902	U2 small nuclear RNA auxiliary factor 2	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0000974-&&-Prp19 complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0089701-&&-U2AF-%%-GO:0000243-&&-commitment complex|molecular_function-&-1&-GO:0030628-&&-pre-mRNA 3'-splice site binding-%%-GO:0008187-&&-poly-pyrimidine tract binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:U2AF2			KEGG-&-1&-hsa03040-&&-Spliceosome	U2AF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF2	0.46453927	0.11190301	315	4	FALSE	U2AF2	U2AF2	147.8434505	0	314	0	0.80788824	FALSE	1	U2AF2	2856034	0.02915981
790358	taxon:9606	2.22719395	0.00136683	173226	1902	SUZ12 polycomb repressive complex 2 subunit	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016571-&&-histone methylation|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0001739-&&-sex chromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0016586-&&-RSC complex-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:SUZ12				SUZ12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUZ12	0.44899547	0.07921098	314	4	FALSE	SUZ12	SUZ12	126.6314103	0	313	0	0.79546768	FALSE	1	SUZ12	2890786	0.02752648
788038	taxon:9606	2.16763825	0.00147293	178317	1902	replication protein A3	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006284-&&-base-excision repair-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006298-&&-mismatch repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005662-&&-DNA replication factor A complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding	G:9606:RPA3			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa03420-&&-Nucleotide excision repair	RPA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA3	0.46133159	0.07000731	312	4	FALSE	RPA3	RPA3	120.0677419	0	311	0	0.80539362	FALSE	1	RPA3	3023716	0.02409483
791331	taxon:9606	2.14337482	0.00274036	169121	1902	SMAD specific E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0061736-&&-engulfment of target by autophagosome-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0007398-&&-ectoderm development-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0071211-&&-protein targeting to vacuole involved in autophagy-%%-GO:0061753-&&-substrate localization to autophagosome-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:1903861-&&-positive regulation of dendrite extension|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005543-&&-phospholipid binding	G:9606:SMURF1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04350-&&-TGF-beta signaling pathway	SMURF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMURF1	0.46655395	0.05416014	312	4	FALSE	SMURF1	SMURF1	119.1	0	311	0	0.80943753	FALSE	1	SMURF1	4038106	0.02324899
793050	taxon:9606	2.12226249	0.00886431	180835	1902	glycogen synthase kinase 3 beta	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0021766-&&-hippocampus development-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:2000738-&&-positive regulation of stem cell differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007623-&&-circadian rhythm-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006611-&&-protein export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0006983-&&-ER overload response-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0036016-&&-cellular response to interleukin-3-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0000320-&&-re-entry into mitotic cell cycle-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0007520-&&-myoblast fusion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0014043-&&-negative regulation of neuron maturation-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:1904339-&&-negative regulation of dopaminergic neuron differentiation-%%-GO:2000077-&&-negative regulation of type B pancreatic cell development-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0044337-&&-canonical Wnt signaling pathway involved in positive regulation of apoptotic process-%%-GO:0071109-&&-superior temporal gyrus development-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:2000466-&&-negative regulation of glycogen (starch) synthase activity-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0007409-&&-axonogenesis-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0016477-&&-cell migration-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0044027-&&-hypermethylation of CpG island|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0002020-&&-protease binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0002039-&&-p53 binding	G:9606:GSK3B	GSK3B	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GSK3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSK3B	0.47119525	0.03140203	312	4	FALSE	GSK3B	GSK3B	90.2	0	311	0	0.81295625	FALSE	1	GSK3B	8386796	0.01719979
787181	taxon:9606	2.09626595	0.00390781	179909	1902	SMAD family member 3	gene	biological_process-&-1&-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0007492-&&-endoderm development-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0030878-&&-thyroid gland development-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0051098-&&-regulation of binding-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:1903243-&&-negative regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0001889-&&-liver development-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0048589-&&-developmental growth-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061767-&&-negative regulation of lung blood pressure-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0050821-&&-protein stabilization-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060290-&&-transdifferentiation-%%-GO:0019049-&&-evasion or tolerance of host defenses by virus-%%-GO:0006955-&&-immune response-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050776-&&-regulation of immune response-%%-GO:0048340-&&-paraxial mesoderm morphogenesis-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006810-&&-transport-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0001707-&&-mesoderm formation-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0002520-&&-immune system development-%%-GO:0032916-&&-positive regulation of transforming growth factor beta3 production-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0001756-&&-somitogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0002076-&&-osteoblast development-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0060039-&&-pericardium development-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001657-&&-ureteric bud development-%%-GO:0042110-&&-T cell activation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042060-&&-wound healing-%%-GO:0045930-&&-negative regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0071144-&&-SMAD2-SMAD3 protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000988-&&-transcription factor activity, protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding	G:9606:SMAD3	SMAD3	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD3	0.47703871	0.05959866	302	4	FALSE	SMAD3	SMAD3	113.38	0	301	0	0.81728901	FALSE	1	SMAD3	5102986	0.02083303
792197	taxon:9606	2.12856468	0.0030679	182445	1902	arrestin beta 2	gene	biological_process-&-1&-GO:0002032-&&-desensitization of G-protein coupled receptor protein signaling pathway by arrestin-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0007628-&&-adult walking behavior-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:0042699-&&-follicle-stimulating hormone signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030168-&&-platelet activation-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0007420-&&-brain development-%%-GO:0045953-&&-negative regulation of natural killer cell mediated cytotoxicity-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0031623-&&-receptor internalization-%%-GO:0034392-&&-negative regulation of smooth muscle cell apoptotic process-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061024-&&-membrane organization-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0032226-&&-positive regulation of synaptic transmission, dopaminergic-%%-GO:0007212-&&-dopamine receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0031826-&&-type 2A serotonin receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0031859-&&-platelet activating factor receptor binding-%%-GO:0031701-&&-angiotensin receptor binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031762-&&-follicle-stimulating hormone receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0031691-&&-alpha-1A adrenergic receptor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0031692-&&-alpha-1B adrenergic receptor binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:ARRB2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway	ARRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRB2	0.46980015	0.07482784	302	4	FALSE	ARRB2	ARRB2	133.8443709	0	302	0	0.81190589	FALSE	0	ARRB2	4558486	0.02558849
788247	taxon:9606	2.2190011	0.0016808	145236	1902	COMMD3-BMI1 readthrough	gene		G:9606:COMMD3-BMI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	COMMD3-BMI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD3-BMI1	0.45065322	0.05633993	301	4	FALSE	COMMD3-BMI1	COMMD3-BMI1	109.1438127	0	300	0	0.79683315	FALSE	1	COMMD3-BMI1	3402896	0.02332133
792030	taxon:9606	2.2190011	0.0016808	182714	1902	BMI1 proto-oncogene, polycomb ring finger	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007379-&&-segment specification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030097-&&-hemopoiesis-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0071535-&&-RING-like zinc finger domain binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:BMI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	BMI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMI1	0.45065322	0.05633993	301	4	FALSE	BMI1	BMI1	109.1438127	0	300	0	0.79683315	FALSE	1	BMI1	3402896	0.02332133
792905	taxon:9606	2.11548763	0.00224309	181184	1902	FUS RNA binding protein	gene	biological_process-&-1&-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0044327-&&-dendritic spine head-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:FUS			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	FUS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUS	0.47270425	0.1094431	297	4	FALSE	FUS	FUS	166.2745763	0	296	0	0.81408539	FALSE	1	FUS	3866674	0.03124683
788213	taxon:9606	2.11533008	0.00405531	178065	1902	RELA proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006117-&&-acetaldehyde metabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032868-&&-response to insulin-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0001889-&&-liver development-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0043200-&&-response to amino acid-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033590-&&-response to cobalamin-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0014040-&&-positive regulation of Schwann cell differentiation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0043278-&&-response to morphine-%%-GO:0007568-&&-aging-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0001942-&&-hair follicle development-%%-GO:0051591-&&-response to cAMP-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0006968-&&-cellular defense response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051607-&&-defense response to virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010033-&&-response to organic substance-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010224-&&-response to UV-B-%%-GO:0032570-&&-response to progesterone-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0071159-&&-NF-kappaB complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0042301-&&-phosphate ion binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0042805-&&-actinin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0071532-&&-ankyrin repeat binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding	G:9606:RELA	RELA	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05134-&&-Legionellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	RELA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RELA	0.47273946	0.06384564	291	4	FALSE	RELA	RELA	122.1072664	0	290	0	0.81411165	FALSE	1	RELA	5272766	0.02293867
787185	taxon:9606	2.14621081	0.0032468	179910	1902	SMAD family member 2	gene	biological_process-&-1&-GO:0035265-&&-organ growth-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1900224-&&-positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry-%%-GO:0045165-&&-cell fate commitment-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0070723-&&-response to cholesterol-%%-GO:0007369-&&-gastrulation-%%-GO:0060021-&&-palate development-%%-GO:0048340-&&-paraxial mesoderm morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0009749-&&-response to glucose-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0051098-&&-regulation of binding-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001707-&&-mesoderm formation-%%-GO:0031016-&&-pancreas development-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0060039-&&-pericardium development-%%-GO:0001706-&&-endoderm formation-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001657-&&-ureteric bud development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0030073-&&-insulin secretion-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007352-&&-zygotic specification of dorsal/ventral axis|cellular_component-&-1&-GO:0071144-&&-SMAD2-SMAD3 protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0032444-&&-activin responsive factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0035326-&&-enhancer binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0070410-&&-co-SMAD binding	G:9606:SMAD2	SMAD2	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD2	0.46593745	0.04848485	288	4	FALSE	SMAD2	SMAD2	103.9965035	0	287	0	0.80896487	FALSE	1	SMAD2	4190114	0.02026009
793219	taxon:9606	2.06507011	0.00371225	180515	1902	heat shock protein family A (Hsp70) member 4	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0045040-&&-protein import into mitochondrial outer membrane-%%-GO:0051131-&&-chaperone-mediated protein complex assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:HSPA4			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04530-&&-Tight junction	HSPA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA4	0.48424506	0.07139202	287	4	FALSE	HSPA4	HSPA4	151.5818815	0	287	0	0.82248831	FALSE	0	HSPA4	5721142	0.02683753
788900	taxon:9606	2.10918544	0.00280172	176650	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0061024-&&-membrane organization-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035308-&&-negative regulation of protein dephosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0016032-&&-viral process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0045296-&&-cadherin binding	G:9606:YWHAB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05161-&&-Hepatitis B	YWHAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAB	0.47411668	0.0633554	286	4	FALSE	YWHAB	YWHAB	128.2711268	0	285	0	0.81513576	FALSE	1	YWHAB	4504532	0.02386818
789451	taxon:9606	2.16054829	0.00409052	175437	1902	BCL2 associated athanogene 3	gene	biological_process-&-1&-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0007420-&&-brain development-%%-GO:0050821-&&-protein stabilization-%%-GO:0034605-&&-cellular response to heat-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0021510-&&-spinal cord development-%%-GO:0010664-&&-negative regulation of striated muscle cell apoptotic process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0032403-&&-protein complex binding	G:9606:BAG3				BAG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG3	0.46284548	0.03583958	284	4	FALSE	BAG3	BAG3	95.13475177	0	283	0	0.80657528	FALSE	1	BAG3	4686616	0.01887592
788394	taxon:9606	2.16275406	0.00109144	177745	1902	staufen double-stranded RNA binding protein 1	gene	biological_process-&-1&-GO:0046726-&&-positive regulation by virus of viral protein levels in host cell-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008157-&&-protein phosphatase 1 binding	G:9606:STAU1				STAU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAU1	0.46237342	0.10604199	282	4	FALSE	STAU1	STAU1	152.8464286	0	281	0	0.80620766	FALSE	1	STAU1	2249260	0.03031323
788373	taxon:9606	2.20655428	0.00296602	177787	1902	SRSF protein kinase 2	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045087-&&-innate immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0035063-&&-nuclear speck organization-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0045787-&&-positive regulation of cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding	G:9606:SRPK2				SRPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPK2	0.45319529	0.04724618	277	4	FALSE	SRPK2	SRPK2	94.65818182	0	276	0	0.79890762	FALSE	1	SRPK2	3433020	0.01991615
792295	taxon:9606	2.14368993	0.00467118	182278	1902	cyclin dependent kinase inhibitor 1A	gene	biological_process-&-1&-GO:0051412-&&-response to corticosterone-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0050821-&&-protein stabilization-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0090399-&&-replicative senescence-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1904031-&&-positive regulation of cyclin-dependent protein kinase activity-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation-%%-GO:0090398-&&-cellular senescence-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0010165-&&-response to X-ray-%%-GO:2000278-&&-regulation of DNA biosynthetic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0070557-&&-PCNA-p21 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019912-&&-cyclin-dependent protein kinase activating kinase activity	G:9606:CDKN1A	CDKN1A	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CDKN1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN1A	0.46648537	0.0477505	277	4	FALSE	CDKN1A	CDKN1A	110.9927273	0	276	0	0.80938501	FALSE	1	CDKN1A	5395404	0.02153097
787827	taxon:9606	2.1458957	0.00488215	178741	1902	mitogen-activated protein kinase 3	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0006915-&&-apoptotic process-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0051216-&&-cartilage development-%%-GO:0030278-&&-regulation of ossification-%%-GO:0060324-&&-face development-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048538-&&-thymus development-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0061308-&&-cardiac neural crest cell development involved in heart development-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0009636-&&-response to toxic substance-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0007411-&&-axon guidance-%%-GO:2000657-&&-negative regulation of apolipoprotein binding-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0060440-&&-trachea formation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0016310-&&-phosphorylation-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005739-&&-mitochondrion-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031143-&&-pseudopodium-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity	G:9606:MAPK3	MAPK3	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05132-&&-Salmonella infection-%%-hsa04720-&&-Long-term potentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05160-&&-Hepatitis C-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction	MAPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK3	0.46600587	0.03739237	273	4	FALSE	MAPK3	MAPK3	96.20664207	0	272	0	0.80901738	FALSE	1	MAPK3	5476580	0.018697
788392	taxon:9606	2.12509847	0.00723854	177751	1902	signal transducer and activator of transcription 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1902728-&&-positive regulation of growth factor dependent skeletal muscle satellite cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0072540-&&-T-helper 17 cell lineage commitment-%%-GO:0007399-&&-nervous system development-%%-GO:0010730-&&-negative regulation of hydrogen peroxide biosynthetic process-%%-GO:0032355-&&-response to estradiol-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0042593-&&-glucose homeostasis-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1904685-&&-positive regulation of metalloendopeptidase activity-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0019953-&&-sexual reproduction-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016310-&&-phosphorylation-%%-GO:0001754-&&-eye photoreceptor cell differentiation-%%-GO:0007568-&&-aging-%%-GO:0044321-&&-response to leptin-%%-GO:0060259-&&-regulation of feeding behavior-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0006954-&&-inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097009-&&-energy homeostasis-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0060019-&&-radial glial cell differentiation-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0006953-&&-acute-phase response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0045471-&&-response to ethanol-%%-GO:0008283-&&-cell proliferation-%%-GO:0042755-&&-eating behavior-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042493-&&-response to drug-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0090575-&&-RNA polymerase II transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding	G:9606:STAT3	STAT3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	STAT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT3	0.47056643	0.04488503	272	4	FALSE	STAT3	STAT3	96.52962963	0	271	0	0.81248359	FALSE	1	STAT3	6910088	0.01833612
788297	taxon:9606	2.10225303	0.0023509	177938	1902	ribosomal protein S27a	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006412-&&-translation-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006413-&&-translational initiation-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006364-&&-rRNA processing-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS27A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27A	0.47568013	0.10211951	271	4	FALSE	RPS27A	RPS27A	158.9405205	0	270	0	0.81629116	FALSE	1	RPS27A	3991914	0.0292432
793311	taxon:9606	2.19048369	0.00160597	180335	1902	histone deacetylase 2	gene	biological_process-&-1&-GO:0071300-&&-cellular response to retinoic acid-%%-GO:2000757-&&-negative regulation of peptidyl-lysine acetylation-%%-GO:0031000-&&-response to caffeine-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0061198-&&-fungiform papilla formation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0001975-&&-response to amphetamine-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0032732-&&-positive regulation of interleukin-1 production-%%-GO:0016358-&&-dendrite development-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045347-&&-negative regulation of MHC class II biosynthetic process-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0042220-&&-response to cocaine-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0061000-&&-negative regulation of dendritic spine development-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0016575-&&-histone deacetylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0035094-&&-response to nicotine-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034605-&&-cellular response to heat-%%-GO:0070301-&&-cellular response to hydrogen peroxide|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)	G:9606:HDAC2			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05165-&&-Human papillomavirus infection	HDAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC2	0.45652018	0.10733507	271	4	FALSE	HDAC2	HDAC2	142.929368	0	270	0	0.80158605	FALSE	1	HDAC2	3186890	0.02927081
790284	taxon:9606	2.1855995	9.56E-04	173441	1902	TAR DNA binding protein	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030264-&&-nuclear fragmentation involved in apoptotic nuclear change-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0006397-&&-mRNA processing-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008380-&&-RNA splicing-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0071765-&&-nuclear inner membrane organization|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035061-&&-interchromatin granule|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding	G:9606:TARDBP				TARDBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARDBP	0.45754037	0.14422271	270	4	FALSE	TARDBP	TARDBP	155.1156716	0	269	0	0.80240008	FALSE	1	TARDBP	1814578	0.0315774
790235	taxon:9606	2.16952891	0.00233707	173556	1902	F-box and WD repeat domain containing 11	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0031648-&&-protein destabilization-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0048511-&&-rhythmic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:FBXW11			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04218-&&-Cellular senescence-%%-hsa05131-&&-Shigellosis	FBXW11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW11	0.46092956	0.04673003	268	4	FALSE	FBXW11	FBXW11	103.1616541	0	267	0	0.80507851	FALSE	1	FBXW11	3108112	0.02059487
793334	taxon:9606	2.27398771	0.00177663	180306	1902	major histocompatibility complex, class I, B	gene	biological_process-&-1&-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0016032-&&-viral process-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0009986-&&-cell surface-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding-%%-GO:0005102-&&-receptor binding	G:9606:HLA-B	HLA-B	TRUE	KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HLA-B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-B	0.43975611	0.03118925	267	4	FALSE	HLA-B	HLA-B	86.40377358	0	266	0	0.78766871	FALSE	1	HLA-B	2418166	0.0198974
792888	taxon:9606	2.20088231	0.00152079	181215	1902	enhancer of zeste 2 polycomb repressive complex 2 subunit	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0097421-&&-liver regeneration-%%-GO:0051154-&&-negative regulation of striated muscle cell differentiation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0070314-&&-G1 to G0 transition-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045605-&&-negative regulation of epidermal cell differentiation-%%-GO:0006325-&&-chromatin organization-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0036333-&&-hepatocyte homeostasis-%%-GO:0070734-&&-histone H3-K27 methylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0014834-&&-skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration-%%-GO:0035984-&&-cellular response to trichostatin A-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0014013-&&-regulation of gliogenesis-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0021695-&&-cerebellar cortex development-%%-GO:1904772-&&-response to tetrachloromethane-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006306-&&-DNA methylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0032355-&&-response to estradiol-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900006-&&-positive regulation of dendrite development-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0045120-&&-pronucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0070878-&&-primary miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0046976-&&-histone methyltransferase activity (H3-K27 specific)-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:EZH2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa00310-&&-Lysine degradation	EZH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EZH2	0.45436323	0.08779813	266	4	FALSE	EZH2	EZH2	137.3598485	0	265	0	0.79985295	FALSE	1	EZH2	2835270	0.02851842
788194	taxon:9606	2.15944541	0.00331141	178102	1902	RB transcriptional corepressor 1	gene	biological_process-&-1&-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0045842-&&-positive regulation of mitotic metaphase/anaphase transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042551-&&-neuron maturation-%%-GO:0051301-&&-cell division-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0071930-&&-negative regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034088-&&-maintenance of mitotic sister chromatid cohesion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0016032-&&-viral process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:0071922-&&-regulation of cohesin loading-%%-GO:0031134-&&-sister chromatid biorientation-%%-GO:0048565-&&-digestive tract development-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0000075-&&-cell cycle checkpoint-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007070-&&-negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0031175-&&-neuron projection development-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005819-&&-spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin-%%-GO:0035189-&&-Rb-E2F complex|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019900-&&-kinase binding	G:9606:RB1	RB1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RB1	0.46308186	0.06707689	265	4	FALSE	RB1	RB1	117.5057034	0	264	0	0.8067591	FALSE	1	RB1	4263556	0.0231616
788932	taxon:9606	2.14132661	0.00139643	176569	1902	cullin 4B	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0007049-&&-cell cycle-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0031175-&&-neuron projection development-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042769-&&-DNA damage response, detection of DNA damage|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL4B			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03420-&&-Nucleotide excision repair	CUL4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL4B	0.46700022	0.11515152	265	4	FALSE	CUL4B	CUL4B	149.3358491	0	265	0	0.8097789	FALSE	0	CUL4B	2540688	0.02877231
792395	taxon:9606	2.13218844	0.00327641	182099	1902	CRK proto-oncogene, adaptor protein	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1990859-&&-cellular response to endothelin-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0035728-&&-response to hepatocyte growth factor-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0001878-&&-response to yeast-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0045953-&&-negative regulation of natural killer cell mediated cytotoxicity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0046875-&&-ephrin receptor binding	G:9606:CRK			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	CRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRK	0.4690017	0.05814751	265	4	FALSE	CRK	CRK	103.9169811	0	265	0	0.81130193	FALSE	0	CRK	4000220	0.01981276
788049	taxon:9606	2.2538207	9.57E-04	178304	1902	ribosomal protein L10	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL10			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10	0.44369102	0.16492033	263	4	FALSE	RPL10	RPL10	134.756654	0	263	0	0.79102988	FALSE	0	RPL10	1617756	0.03007706
789029	taxon:9606	2.19316212	0.00159468	176334	1902	ubiquitin like 4A	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0071816-&&-tail-anchored membrane protein insertion into ER membrane-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0071818-&&-BAT3 complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding	G:9606:UBL4A				UBL4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBL4A	0.45596264	0.11296549	263	4	FALSE	UBL4A	UBL4A	130.8897338	0	263	0	0.80113965	FALSE	0	UBL4A	2485918	0.02691387
791878	taxon:9606	2.15613676	0.00232526	182933	1902	poly(ADP-ribose) polymerase 1	gene	biological_process-&-1&-GO:0032042-&&-mitochondrial DNA metabolic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0036211-&&-protein modification process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1903376-&&-regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0071294-&&-cellular response to zinc ion-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:1904646-&&-cellular response to beta-amyloid-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0016540-&&-protein autoprocessing-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:1904044-&&-response to aldosterone-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0006302-&&-double-strand break repair-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:1990966-&&-ATP generation from poly-ADP-D-ribose-%%-GO:1904762-&&-positive regulation of myofibroblast differentiation-%%-GO:2001170-&&-negative regulation of ATP biosynthetic process-%%-GO:0043504-&&-mitochondrial DNA repair-%%-GO:0010990-&&-regulation of SMAD protein complex assembly-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0070212-&&-protein poly-ADP-ribosylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0034599-&&-cellular response to oxidative stress|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005635-&&-nuclear envelope-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0003910-&&-DNA ligase (ATP) activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0051287-&&-NAD binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:PARP1	PARP1	TRUE	KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa04210-&&-Apoptosis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis	PARP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP1	0.46379247	0.10733591	262	4	FALSE	PARP1	PARP1	166.5846154	0	261	0	0.80731054	FALSE	1	PARP1	4076254	0.03266139
792083	taxon:9606	2.11627541	0.00243734	182647	1902	clathrin heavy chain	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0051301-&&-cell division-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0060236-&&-regulation of mitotic spindle organization-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0033572-&&-transferrin transport-%%-GO:0031623-&&-receptor internalization-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006914-&&-autophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane|cellular_component-&-1&-GO:1990498-&&-mitotic spindle microtubule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005768-&&-endosome-%%-GO:0030118-&&-clathrin coat-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0071439-&&-clathrin complex-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032051-&&-clathrin light chain binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:CLTC			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05016-&&-Huntington disease-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle	CLTC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLTC	0.47252829	0.08431838	262	4	FALSE	CLTC	CLTC	157.0346154	0	261	0	0.8139541	FALSE	1	CLTC	3934000	0.02933438
787977	taxon:9606	2.16212384	0.00225035	178478	1902	proliferating cell nuclear antigen	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0031297-&&-replication fork processing-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0007507-&&-heart development-%%-GO:0044849-&&-estrous cycle-%%-GO:0097421-&&-liver regeneration-%%-GO:0000723-&&-telomere maintenance-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006298-&&-mismatch repair-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0019985-&&-translesion synthesis-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0032077-&&-positive regulation of deoxyribonuclease activity-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:1902990-&&-mitotic telomere maintenance via semi-conservative replication-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0034644-&&-cellular response to UV-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0032355-&&-response to estradiol-%%-GO:0008283-&&-cell proliferation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0046686-&&-response to cadmium ion|cellular_component-&-1&-GO:0070557-&&-PCNA-p21 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0030894-&&-replisome-%%-GO:0005657-&&-replication fork-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0043626-&&-PCNA complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0000701-&&-purine-specific mismatch base pair DNA N-glycosylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0032139-&&-dinucleotide insertion or deletion binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030337-&&-DNA polymerase processivity factor activity-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:PCNA	PCNA	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa04110-&&-Cell cycle-%%-hsa03410-&&-Base excision repair-%%-hsa03030-&&-DNA replication-%%-hsa04530-&&-Tight junction-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05161-&&-Hepatitis B	PCNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCNA	0.4625082	0.07839411	260	4	FALSE	PCNA	PCNA	142.2790698	0	259	0	0.80631269	FALSE	1	PCNA	3569768	0.02809312
792983	taxon:9606	2.1044588	0.00323864	181041	1902	filamin A	gene	biological_process-&-1&-GO:0034394-&&-protein localization to cell surface-%%-GO:0045184-&&-establishment of protein localization-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0043113-&&-receptor clustering-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1905031-&&-regulation of membrane repolarization during cardiac muscle cell action potential-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:1905000-&&-regulation of membrane repolarization during atrial cardiac muscle cell action potential-%%-GO:0060271-&&-cilium assembly-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0016479-&&-negative regulation of transcription from RNA polymerase I promoter-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0034329-&&-cell junction assembly-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0030168-&&-platelet activation-%%-GO:0050821-&&-protein stabilization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007195-&&-adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002576-&&-platelet degranulation-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:2001046-&&-positive regulation of integrin-mediated signaling pathway-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043198-&&-dendritic shaft-%%-GO:0097440-&&-apical dendrite-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031941-&&-filamentous actin-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0031012-&&-extracellular matrix-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005730-&&-nucleolus-%%-GO:0031523-&&-Myb complex-%%-GO:0016020-&&-membrane-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0031852-&&-mu-type opioid receptor binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0034988-&&-Fc-gamma receptor I complex binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:FLNA			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNA	0.47518155	0.09115314	260	4	FALSE	FLNA	FLNA	156.2170543	0	259	0	0.81592353	FALSE	1	FLNA	4745876	0.02879751
791890	taxon:9606	2.238853	0.00649979	182922	1902	adrenoceptor beta 2	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0061024-&&-membrane organization-%%-GO:1901098-&&-positive regulation of autophagosome maturation-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0002032-&&-desensitization of G-protein coupled receptor protein signaling pathway by arrestin-%%-GO:0031649-&&-heat generation-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045986-&&-negative regulation of smooth muscle contraction-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0002025-&&-vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1904504-&&-positive regulation of lipophagy-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0040015-&&-negative regulation of multicellular organism growth-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045453-&&-bone resorption-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0007267-&&-cell-cell signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005634-&&-nucleus-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051380-&&-norepinephrine binding-%%-GO:0004941-&&-beta2-adrenergic receptor activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0051379-&&-epinephrine binding-%%-GO:0008179-&&-adenylate cyclase binding	G:9606:ADRB2	ADRB2	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRB2	0.44665728	0.03079402	259	4	FALSE	ADRB2	ADRB2	83.56809339	0	258	0	0.7935245	FALSE	1	ADRB2	8286400	0.01832973
787267	taxon:9606	2.15755475	0.00342921	179779	1902	Jun proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0031103-&&-axon regeneration-%%-GO:0034097-&&-response to cytokine-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0001889-&&-liver development-%%-GO:0042493-&&-response to drug-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0009314-&&-response to radiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0045657-&&-positive regulation of monocyte differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007612-&&-learning-%%-GO:0010941-&&-regulation of cell death-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0001525-&&-angiogenesis-%%-GO:0051365-&&-cellular response to potassium ion starvation-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0051591-&&-response to cAMP-%%-GO:0001774-&&-microglial cell activation-%%-GO:0007568-&&-aging-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007623-&&-circadian rhythm-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0035026-&&-leading edge cell differentiation-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0051899-&&-membrane depolarization-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0060395-&&-SMAD protein signal transduction|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0044212-&&-transcription regulatory region DNA binding	G:9606:JUN	JUN	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05030-&&-Cocaine addiction-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05323-&&-Rheumatoid arthritis	JUN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUN	0.46348766	0.07251564	256	4	FALSE	JUN	JUN	110.3818898	0	255	0	0.80707421	FALSE	1	JUN	4166510	0.02167636
789127	taxon:9606	2.14368993	0.00284158	176150	1902	beta-transducin repeat containing E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0048511-&&-rhythmic process-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0031648-&&-protein destabilization-%%-GO:0007165-&&-signal transduction-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:BTRC			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04218-&&-Cellular senescence-%%-hsa05131-&&-Shigellosis	BTRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTRC	0.46648537	0.05527372	256	4	FALSE	BTRC	BTRC	115.2086614	0	255	0	0.80938501	FALSE	1	BTRC	3709292	0.02222362
792133	taxon:9606	2.09547818	0.0027967	182542	1902	actin beta	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0098974-&&-postsynaptic actin cytoskeleton organization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034329-&&-cell junction assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048013-&&-ephrin receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097433-&&-dense body-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043209-&&-myelin sheath-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0072562-&&-blood microparticle-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex|molecular_function-&-1&-GO:0098973-&&-structural constituent of postsynaptic actin cytoskeleton-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ACTB			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	ACTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTB	0.47721805	0.08163456	256	4	FALSE	ACTB	ACTB	157.6220472	0	255	0	0.8174203	FALSE	1	ACTB	4395942	0.02871455
787378	taxon:9606	2.12163227	0.00219831	179529	1902	myosin heavy chain 9	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0015031-&&-protein transport-%%-GO:0030224-&&-monocyte differentiation-%%-GO:1903923-&&-positive regulation of protein processing in phagocytic vesicle-%%-GO:0070527-&&-platelet aggregation-%%-GO:0051295-&&-establishment of meiotic spindle localization-%%-GO:0001525-&&-angiogenesis-%%-GO:0032796-&&-uropod organization-%%-GO:1903919-&&-negative regulation of actin filament severing-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000910-&&-cytokinesis-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0030220-&&-platelet formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0001768-&&-establishment of T cell polarity-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0007520-&&-myoblast fusion-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0043534-&&-blood vessel endothelial cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016460-&&-myosin II complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005826-&&-actomyosin contractile ring-%%-GO:0042641-&&-actomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0043234-&&-protein complex-%%-GO:0001726-&&-ruffle-%%-GO:0097513-&&-myosin II filament-%%-GO:0031012-&&-extracellular matrix-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0008305-&&-integrin complex-%%-GO:0005634-&&-nucleus-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005925-&&-focal adhesion-%%-GO:0031252-&&-cell leading edge-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0043495-&&-protein anchor-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0003774-&&-motor activity	G:9606:MYH9			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYH9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH9	0.47133521	0.09395194	253	4	FALSE	MYH9	MYH9	141.4980237	0	253	0	0.81306129	FALSE	0	MYH9	3538140	0.0265809
787811	taxon:9606	2.15046479	0.00555081	178758	1902	protein kinase C alpha	gene	biological_process-&-1&-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0035408-&&-histone H3-T6 phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0002159-&&-desmosome assembly-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2000707-&&-positive regulation of dense core granule biogenesis-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0030168-&&-platelet activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0001525-&&-angiogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007411-&&-axon guidance-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0045785-&&-positive regulation of cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0035403-&&-histone kinase activity (H3-T6 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PRKCA	PRKCA	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04713-&&-Circadian entrainment-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04970-&&-Salivary secretion-%%-hsa05225-&&-Hepatocellular carcinoma	PRKCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCA	0.46501575	0.03816867	252	4	FALSE	PRKCA	PRKCA	103.316	0	251	0	0.80825587	FALSE	1	PRKCA	5889152	0.02012081
788512	taxon:9606	2.2802899	0.00218019	177525	1902	SRY-box 2	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0042246-&&-tissue regeneration-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001654-&&-eye development-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006325-&&-chromatin organization-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0070848-&&-response to growth factor-%%-GO:0021983-&&-pituitary gland development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0009611-&&-response to wounding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0048839-&&-inner ear development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0021781-&&-glial cell fate commitment-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0022409-&&-positive regulation of cell-cell adhesion-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding	G:9606:SOX2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX2	0.43854073	0.03498795	252	4	FALSE	SOX2	SOX2	83.66	0	251	0	0.78661835	FALSE	1	SOX2	2681746	0.0193904
791854	taxon:9606	2.09721128	0.00288742	182975	1902	ABL proto-oncogene 1, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:1904528-&&-positive regulation of microtubule binding-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:1900275-&&-negative regulation of phospholipase C activity-%%-GO:0045087-&&-innate immune response-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1904531-&&-positive regulation of actin filament binding-%%-GO:0051882-&&-mitochondrial depolarization-%%-GO:0002333-&&-transitional one stage B cell differentiation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006914-&&-autophagy-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048538-&&-thymus development-%%-GO:0048668-&&-collateral sprouting-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0060563-&&-neuroepithelial cell differentiation-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:0031113-&&-regulation of microtubule polymerization-%%-GO:0030035-&&-microspike assembly-%%-GO:1903053-&&-regulation of extracellular matrix organization-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0002322-&&-B cell proliferation involved in immune response-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0006979-&&-response to oxidative stress-%%-GO:1900042-&&-positive regulation of interleukin-2 secretion-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006298-&&-mismatch repair-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050798-&&-activated T cell proliferation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0048536-&&-spleen development-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0072358-&&-cardiovascular system development-%%-GO:1902715-&&-positive regulation of interferon-gamma secretion-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0090135-&&-actin filament branching-%%-GO:0021587-&&-cerebellum morphogenesis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:1990051-&&-activation of protein kinase C activity-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0009791-&&-post-embryonic development-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0031252-&&-cell leading edge-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0004515-&&-nicotinate-nucleotide adenylyltransferase activity-%%-GO:0030145-&&-manganese ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005102-&&-receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0003677-&&-DNA binding	G:9606:ABL1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04110-&&-Cell cycle-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis	ABL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABL1	0.47682368	0.07434538	252	4	FALSE	ABL1	ABL1	133.94	0	251	0	0.81713145	FALSE	1	ABL1	4040208	0.02443196
787131	taxon:9606	2.2005672	0.00118158	180015	1902	interleukin enhancer binding factor 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051607-&&-defense response to virus-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:ILF3				ILF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILF3	0.4544283	0.16073973	249	4	FALSE	ILF3	ILF3	177.9558233	0	249	0	0.79990547	FALSE	0	ILF3	2398428	0.03681932
787543	taxon:9606	2.06396723	0.0017827	162832	1902	tubulin beta class I	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0007017-&&-microtubule-based process-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0051301-&&-cell division-%%-GO:0009987-&&-cellular process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0044297-&&-cell body-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0042288-&&-MHC class I protein binding	G:9606:TUBB			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB	0.48450382	0.1085876	247	4	FALSE	TUBB	TUBB	187.3765182	0	247	0	0.82267213	FALSE	0	TUBB	3714956	0.03288461
788400	taxon:9606	2.13155822	0.00278851	177736	1902	aurora kinase A	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:1900195-&&-positive regulation of oocyte maturation-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0051301-&&-cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007100-&&-mitotic centrosome separation-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007051-&&-spindle organization-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:1990138-&&-neuron projection extension-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007057-&&-spindle assembly involved in female meiosis I-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051642-&&-centrosome localization-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046605-&&-regulation of centrosome cycle|cellular_component-&-1&-GO:0031616-&&-spindle pole centrosome-%%-GO:0005929-&&-cilium-%%-GO:0072687-&&-meiotic spindle-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0043203-&&-axon hillock-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0051233-&&-spindle midzone-%%-GO:0005813-&&-centrosome-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0045120-&&-pronucleus-%%-GO:0042585-&&-germinal vesicle-%%-GO:0072686-&&-mitotic spindle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005524-&&-ATP binding	G:9606:AURKA			KEGG-&-1&-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	AURKA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AURKA	0.46914037	0.05888257	247	4	FALSE	AURKA	AURKA	127.7714286	0	246	0	0.81140696	FALSE	1	AURKA	3614418	0.02424656
792266	taxon:9606	2.12966756	0.00215496	182318	1902	cyclin dependent kinase 1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0014075-&&-response to amine-%%-GO:0051301-&&-cell division-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0008283-&&-cell proliferation-%%-GO:0034501-&&-protein localization to kinetochore-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030261-&&-chromosome condensation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0007344-&&-pronuclear fusion-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0044772-&&-mitotic cell cycle phase transition-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0014038-&&-regulation of Schwann cell differentiation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0007569-&&-cell aging-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051445-&&-regulation of meiotic cell cycle-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0046688-&&-response to copper ion-%%-GO:0048678-&&-response to axon injury-%%-GO:0006281-&&-DNA repair-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:0014823-&&-response to activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007098-&&-centrosome cycle-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005739-&&-mitochondrion-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0035173-&&-histone kinase activity-%%-GO:0097472-&&-cyclin-dependent protein kinase activity	G:9606:CDK1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK1	0.46955685	0.07390432	247	4	FALSE	CDK1	CDK1	144.322449	0	246	0	0.81172207	FALSE	1	CDK1	3464074	0.02732916
792909	taxon:9606	2.22892705	0.00278556	181171	1902	FYN proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007612-&&-learning-%%-GO:0045087-&&-innate immune response-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0031295-&&-T cell costimulation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0030168-&&-platelet activation-%%-GO:1904645-&&-response to beta-amyloid-%%-GO:0016477-&&-cell migration-%%-GO:0002250-&&-adaptive immune response-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007596-&&-blood coagulation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:1902951-&&-negative regulation of dendritic spine maintenance-%%-GO:0007631-&&-feeding behavior-%%-GO:0007411-&&-axon guidance-%%-GO:1905664-&&-regulation of calcium ion import across plasma membrane-%%-GO:0006816-&&-calcium ion transport-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0007417-&&-central nervous system development-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0042110-&&-T cell activation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001764-&&-neuron migration-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0050798-&&-activated T cell proliferation-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0030154-&&-cell differentiation-%%-GO:0045471-&&-response to ethanol-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030900-&&-forebrain development-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0030425-&&-dendrite-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005884-&&-actin filament-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0042608-&&-T cell receptor binding-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0042610-&&-CD8 receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0070851-&&-growth factor receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0015631-&&-tubulin binding	G:9606:FYN			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa05416-&&-Viral myocarditis-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa05020-&&-Prion diseases-%%-hsa04520-&&-Adherens junction-%%-hsa04660-&&-T cell receptor signaling pathway	FYN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FYN	0.44864636	0.05666869	246	4	FALSE	FYN	FYN	83.56147541	0	245	0	0.79517882	FALSE	1	FYN	3112258	0.01796492
792915	taxon:9606	2.130928	0.00203477	181163	1902	X-ray repair cross complementing 6	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000723-&&-telomere maintenance-%%-GO:0006310-&&-DNA recombination-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071475-&&-cellular hyperosmotic salinity response-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0097680-&&-double-strand break repair via classical nonhomologous end joining-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043564-&&-Ku70:Ku80 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0051575-&&-5'-deoxyribose-5-phosphate lyase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:XRCC6			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	XRCC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC6	0.46927911	0.09201916	246	4	FALSE	XRCC6	XRCC6	167.397541	0	245	0	0.811512	FALSE	1	XRCC6	3545000	0.0317318
787821	taxon:9606	2.09264219	0.00174583	178745	1902	protein kinase, DNA-activated, catalytic polypeptide	gene	biological_process-&-1&-GO:0002326-&&-B cell lineage commitment-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0014823-&&-response to activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0002684-&&-positive regulation of immune system process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0008283-&&-cell proliferation-%%-GO:0002360-&&-T cell lineage commitment-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0097681-&&-double-strand break repair via alternative nonhomologous end joining-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016233-&&-telomere capping-%%-GO:0048536-&&-spleen development-%%-GO:2001229-&&-negative regulation of response to gamma radiation-%%-GO:0048538-&&-thymus development-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0033153-&&-T cell receptor V(D)J recombination-%%-GO:0001756-&&-somitogenesis-%%-GO:0002638-&&-negative regulation of immunoglobulin production-%%-GO:0007420-&&-brain development-%%-GO:0031648-&&-protein destabilization-%%-GO:0006302-&&-double-strand break repair-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0048511-&&-rhythmic process-%%-GO:0072431-&&-signal transduction involved in mitotic G1 DNA damage checkpoint-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005958-&&-DNA-dependent protein kinase-DNA ligase 4 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0004677-&&-DNA-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005524-&&-ATP binding	G:9606:PRKDC			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03450-&&-Non-homologous end-joining	PRKDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKDC	0.47786478	0.09884937	242	4	FALSE	PRKDC	PRKDC	186.925	0	241	0	0.81789297	FALSE	1	PRKDC	3701004	0.03385021
787532	taxon:9606	2.12368048	0.00272792	179233	1902	protein phosphatase 1 catalytic subunit alpha	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0016311-&&-dephosphorylation-%%-GO:0051301-&&-cell division-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0030324-&&-lung development-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0036496-&&-regulation of translational initiation by eIF2 alpha dephosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0005981-&&-regulation of glycogen catabolic process-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0042587-&&-glycogen granule-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:PPP1CA			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04218-&&-Cellular senescence-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa03015-&&-mRNA surveillance pathway	PPP1CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CA	0.47088063	0.07285257	241	4	FALSE	PPP1CA	PPP1CA	147.083682	0	240	0	0.81271992	FALSE	1	PPP1CA	3944034	0.02763739
790056	taxon:9606	2.14825902	0.00308233	173985	1902	cell division cycle 37	gene	biological_process-&-1&-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0050821-&&-protein stabilization-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0006457-&&-protein folding-%%-GO:0006605-&&-protein targeting-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:1990565-&&-HSP90-CDC37 chaperone complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CDC37			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	CDC37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC37	0.46549322	0.05569424	241	4	FALSE	CDC37	CDC37	117.0711297	0	240	0	0.8086235	FALSE	1	CDC37	3744922	0.02264742
788933	taxon:9606	2.20434851	0.00107202	176568	1902	cullin 4A	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0051246-&&-regulation of protein metabolic process-%%-GO:2000819-&&-regulation of nucleotide-excision repair-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0030097-&&-hemopoiesis-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL4A			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03420-&&-Nucleotide excision repair	CUL4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL4A	0.45364877	0.10793178	240	4	FALSE	CUL4A	CUL4A	148.4453782	0	239	0	0.79927525	FALSE	1	CUL4A	2167934	0.03075226
793364	taxon:9606	2.11501497	0.00111207	180233	1902	heterogeneous nuclear ribonucleoprotein K	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:1902165-&&-regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0007165-&&-signal transduction-%%-GO:0045716-&&-positive regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0072369-&&-regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010467-&&-gene expression-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010988-&&-regulation of low-density lipoprotein particle clearance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042995-&&-cell projection-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:HNRNPK			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03040-&&-Spliceosome	HNRNPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPK	0.47280989	0.15161508	240	4	FALSE	HNRNPK	HNRNPK	205.1218487	0	239	0	0.81416417	FALSE	1	HNRNPK	2669112	0.03809763
787223	taxon:9606	2.17866709	0.00107351	179833	1902	minichromosome maintenance complex component 5	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003688-&&-DNA replication origin binding	G:9606:MCM5			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM5	0.45899624	0.11835027	239	4	FALSE	MCM5	MCM5	166.5313808	0	239	0	0.80355549	FALSE	0	MCM5	2323644	0.03343836
789808	taxon:9606	2.10776745	0.0029672	174615	1902	STIP1 homology and U-box containing protein 1	gene	biological_process-&-1&-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051604-&&-protein maturation-%%-GO:0036503-&&-ERAD pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0031943-&&-regulation of glucocorticoid metabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0090035-&&-positive regulation of chaperone-mediated protein complex assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0031371-&&-ubiquitin conjugating enzyme complex|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046332-&&-SMAD binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0030911-&&-TPR domain binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:STUB1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	STUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STUB1	0.47443564	0.06447114	239	4	FALSE	STUB1	STUB1	122.4936709	0	238	0	0.81537209	FALSE	1	STUB1	3740008	0.02257143
790275	taxon:9606	2.21474712	0.00225108	173461	1902	sirtuin 1	gene	biological_process-&-1&-GO:0031937-&&-positive regulation of chromatin silencing-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031648-&&-protein destabilization-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0071441-&&-negative regulation of histone H3-K14 acetylation-%%-GO:0031393-&&-negative regulation of prostaglandin biosynthetic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000012-&&-single strand break repair-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0006364-&&-rRNA processing-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070857-&&-regulation of bile acid biosynthetic process-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0044321-&&-response to leptin-%%-GO:0032071-&&-regulation of endodeoxyribonuclease activity-%%-GO:0071900-&&-regulation of protein serine/threonine kinase activity-%%-GO:0000720-&&-pyrimidine dimer repair by nucleotide-excision repair-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034391-&&-regulation of smooth muscle cell apoptotic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006281-&&-DNA repair-%%-GO:0006343-&&-establishment of chromatin silencing-%%-GO:0010934-&&-macrophage cytokine production-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0006260-&&-DNA replication-%%-GO:0007517-&&-muscle organ development-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0018394-&&-peptidyl-lysine acetylation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0051097-&&-negative regulation of helicase activity-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007569-&&-cell aging-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:1990619-&&-histone H3-K9 deacetylation-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0010883-&&-regulation of lipid storage-%%-GO:0032868-&&-response to insulin-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006476-&&-protein deacetylation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:2000619-&&-negative regulation of histone H4-K16 acetylation-%%-GO:2000655-&&-negative regulation of cellular response to testosterone stimulus-%%-GO:0035356-&&-cellular triglyceride homeostasis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904179-&&-positive regulation of adipose tissue development-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation-%%-GO:0035358-&&-regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000111-&&-positive regulation of macrophage apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006325-&&-chromatin organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0006642-&&-triglyceride mobilization-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0001525-&&-angiogenesis-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061647-&&-histone H3-K9 modification-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0042595-&&-behavioral response to starvation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:2000757-&&-negative regulation of peptidyl-lysine acetylation-%%-GO:0006342-&&-chromatin silencing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0016605-&&-PML body-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0033553-&&-rDNA heterochromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0019213-&&-deacetylase activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:1990254-&&-keratin filament binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0017136-&&-NAD-dependent histone deacetylase activity-%%-GO:0043398-&&-HLH domain binding-%%-GO:0002039-&&-p53 binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0046969-&&-NAD-dependent histone deacetylase activity (H3-K9 specific)-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SIRT1	SIRT1	TRUE	KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	SIRT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT1	0.45151882	0.07491239	239	4	FALSE	SIRT1	SIRT1	129.9704641	0	238	0	0.79754215	FALSE	1	SIRT1	3344882	0.0273449
792609	taxon:9606	2.23522924	0.0020835	165346	1902	leucine rich repeat kinase 2	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006897-&&-endocytosis-%%-GO:0035564-&&-regulation of kidney size-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0007040-&&-lysosome organization-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:2000172-&&-regulation of branching morphogenesis of a nerve-%%-GO:0021772-&&-olfactory bulb development-%%-GO:1903125-&&-negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation-%%-GO:1904887-&&-Wnt signalosome assembly-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0040012-&&-regulation of locomotion-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0014041-&&-regulation of neuron maturation-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:1905289-&&-regulation of CAMKK-AMPK signaling cascade-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0051900-&&-regulation of mitochondrial depolarization-%%-GO:0022028-&&-tangential migration from the subventricular zone to the olfactory bulb-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0046039-&&-GTP metabolic process-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:1902803-&&-regulation of synaptic vesicle transport-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0070997-&&-neuron death-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007030-&&-Golgi organization-%%-GO:0016310-&&-phosphorylation-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:0010506-&&-regulation of autophagy-%%-GO:1905279-&&-regulation of retrograde transport, endosome to Golgi-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:1902499-&&-positive regulation of protein autoubiquitination-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034613-&&-cellular protein localization-%%-GO:0035640-&&-exploration behavior-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:1903215-&&-negative regulation of protein targeting to mitochondrion-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:1902823-&&-negative regulation of late endosome to lysosome transport-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0035751-&&-regulation of lysosomal lumen pH-%%-GO:1903217-&&-negative regulation of protein processing involved in protein targeting to mitochondrion-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0051646-&&-mitochondrion localization-%%-GO:0060161-&&-positive regulation of dopamine receptor signaling pathway-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:1902692-&&-regulation of neuroblast proliferation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006914-&&-autophagy-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030424-&&-axon-%%-GO:0043195-&&-terminal bouton-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0044754-&&-autolysosome-%%-GO:0099400-&&-caveola neck-%%-GO:0005634-&&-nucleus-%%-GO:0016234-&&-inclusion body-%%-GO:0043025-&&-neuronal cell body-%%-GO:0043204-&&-perikaryon-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005902-&&-microvillus-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0044753-&&-amphisome-%%-GO:0070062-&&-extracellular exosome-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0097487-&&-multivesicular body, internal vesicle-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030425-&&-dendrite-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005768-&&-endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005615-&&-extracellular space-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0030426-&&-growth cone-%%-GO:0098794-&&-postsynapse-%%-GO:0043005-&&-neuron projection-%%-GO:0032473-&&-cytoplasmic side of mitochondrial outer membrane-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0003779-&&-actin binding-%%-GO:0005525-&&-GTP binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0034211-&&-GTP-dependent protein kinase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0030276-&&-clathrin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000149-&&-SNARE binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0039706-&&-co-receptor binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0036479-&&-peroxidase inhibitor activity-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:1904713-&&-beta-catenin destruction complex binding	G:9606:LRRK2			KEGG-&-1&-hsa05012-&&-Parkinson disease	LRRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRK2	0.44738141	0.05658132	238	4	FALSE	LRRK2	LRRK2	117.4915254	0	237	0	0.79412846	FALSE	1	LRRK2	3174458	0.02543658
792408	taxon:9606	2.17015913	0.00506927	182071	1902	mitogen-activated protein kinase 14	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0098586-&&-cellular response to virus-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0001890-&&-placenta development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030278-&&-regulation of ossification-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0001502-&&-cartilage condensation-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0001525-&&-angiogenesis-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006935-&&-chemotaxis-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0014835-&&-myoblast differentiation involved in skeletal muscle regeneration-%%-GO:0090336-&&-positive regulation of brown fat cell differentiation-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:2001184-&&-positive regulation of interleukin-12 secretion-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051146-&&-striated muscle cell differentiation|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0004707-&&-MAP kinase activity	G:9606:MAPK14	MAPK14	TRUE	KEGG-&-1&-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK14	0.4607957	0.03833062	235	4	FALSE	MAPK14	MAPK14	97.34334764	0	234	0	0.80497348	FALSE	1	MAPK14	5027212	0.01938432
787678	taxon:9606	2.18701749	0.00308671	178964	1902	phosphoinositide-3-kinase regulatory subunit 1	gene	biological_process-&-1&-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0050821-&&-protein stabilization-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0051531-&&-NFAT protein import into nucleus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0005737-&&-cytoplasm-%%-GO:0005943-&&-phosphatidylinositol 3-kinase complex, class IA-%%-GO:1990578-&&-perinuclear endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0043559-&&-insulin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0035014-&&-phosphatidylinositol 3-kinase regulator activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity	G:9606:PIK3R1	PIK3R1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R1	0.45724371	0.07583221	234	4	FALSE	PIK3R1	PIK3R1	102.375	0	233	0	0.80216375	FALSE	1	PIK3R1	3574214	0.02076135
789426	taxon:9606	2.25240271	5.57E-04	175515	1902	eukaryotic translation initiation factor 4A3	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0008306-&&-associative learning-%%-GO:1904574-&&-negative regulation of selenocysteine insertion sequence binding-%%-GO:0006364-&&-rRNA processing-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072715-&&-cellular response to selenite ion-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:1904570-&&-negative regulation of selenocysteine incorporation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0035640-&&-exploration behavior-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006369-&&-termination of RNA polymerase II transcription|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0035368-&&-selenocysteine insertion sequence binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0008143-&&-poly(A) binding	G:9606:EIF4A3			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	EIF4A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A3	0.44397034	0.14991043	234	4	FALSE	EIF4A3	EIF4A3	166.5474138	0	233	0	0.79126622	FALSE	1	EIF4A3	1414034	0.03683767
792199	taxon:9606	2.16196628	0.00198922	182446	1902	arrestin beta 1	gene	biological_process-&-1&-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0015031-&&-protein transport-%%-GO:0007602-&&-phototransduction-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0032717-&&-negative regulation of interleukin-8 production-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0042699-&&-follicle-stimulating hormone signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0030168-&&-platelet activation-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0061024-&&-membrane organization|cellular_component-&-1&-GO:0043197-&&-dendritic spine-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031143-&&-pseudopodium-%%-GO:0000785-&&-chromatin-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0031701-&&-angiotensin receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0035612-&&-AP-2 adaptor complex binding-%%-GO:0031896-&&-V2 vasopressin receptor binding-%%-GO:0045309-&&-protein phosphorylated amino acid binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031762-&&-follicle-stimulating hormone receptor binding-%%-GO:0031691-&&-alpha-1A adrenergic receptor binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0031692-&&-alpha-1B adrenergic receptor binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding	G:9606:ARRB1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway	ARRB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRB1	0.4625419	0.06615362	233	4	FALSE	ARRB1	ARRB1	135.832618	0	233	0	0.80633895	FALSE	0	ARRB1	3042348	0.02666708
788787	taxon:9606	2.18827793	0.0018576	176903	1902	ubiquitin specific peptidase 7	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0035616-&&-histone H2B conserved C-terminal lysine deubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1904353-&&-regulation of telomere capping-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016032-&&-viral process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0002039-&&-p53 binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008134-&&-transcription factor binding	G:9606:USP7			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	USP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP7	0.45698034	0.05902858	231	4	FALSE	USP7	USP7	133.069869	0	230	0	0.80195368	FALSE	1	USP7	2836602	0.02699202
792476	taxon:9606	2.25098472	0.00132973	181957	1902	BRCA1 associated RING domain 1	gene	biological_process-&-1&-GO:0001894-&&-tissue homeostasis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000732-&&-strand displacement-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0031441-&&-negative regulation of mRNA 3'-end processing|cellular_component-&-1&-GO:0031436-&&-BRCA1-BARD1 complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019900-&&-kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:BARD1			KEGG-&-1&-hsa03440-&&-Homologous recombination	BARD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BARD1	0.44425002	0.06251436	231	4	FALSE	BARD1	BARD1	117.4497817	0	230	0	0.79150255	FALSE	1	BARD1	2165818	0.02589082
787054	taxon:9606	2.260438	0.00135169	180156	1902	interferon gamma inducible protein 16	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0051607-&&-defense response to virus-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:2000117-&&-negative regulation of cysteine-type endopeptidase activity-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:IFI16			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	IFI16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFI16	0.44239214	0.03782039	230	4	FALSE	IFI16	IFI16	87.13913043	0	230	0	0.789927	FALSE	0	IFI16	1833142	0.01947336
788239	taxon:9606	2.14195683	0.00186691	178027	1902	SHC adaptor protein 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007507-&&-heart development-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001525-&&-angiogenesis-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0040008-&&-regulation of growth-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045740-&&-positive regulation of DNA replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0070435-&&-Shc-EGFR complex|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0048408-&&-epidermal growth factor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005543-&&-phospholipid binding	G:9606:SHC1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SHC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHC1	0.46686282	0.08775794	230	4	FALSE	SHC1	SHC1	124.5877193	0	229	0	0.80967386	FALSE	1	SHC1	2847854	0.0238574
789631	taxon:9606	2.11911139	0.00211067	175024	1902	histone deacetylase 6	gene	biological_process-&-1&-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070845-&&-polyubiquitinated misfolded protein transport-%%-GO:0016575-&&-histone deacetylation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0090035-&&-positive regulation of chaperone-mediated protein complex assembly-%%-GO:0006914-&&-autophagy-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048668-&&-collateral sprouting-%%-GO:0006476-&&-protein deacetylation-%%-GO:0051788-&&-response to misfolded protein-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0045598-&&-regulation of fat cell differentiation-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0060632-&&-regulation of microtubule-based movement-%%-GO:0032418-&&-lysosome localization-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0090042-&&-tubulin deacetylation-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0043241-&&-protein complex disassembly-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0070846-&&-Hsp90 deacetylation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0070848-&&-response to growth factor-%%-GO:0010033-&&-response to organic substance-%%-GO:0035967-&&-cellular response to topologically incorrect protein-%%-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0009636-&&-response to toxic substance-%%-GO:1901300-&&-positive regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0060271-&&-cilium assembly-%%-GO:0010727-&&-negative regulation of hydrogen peroxide metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0051354-&&-negative regulation of oxidoreductase activity-%%-GO:0043242-&&-negative regulation of protein complex disassembly-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0070842-&&-aggresome assembly-%%-GO:0051646-&&-mitochondrion localization-%%-GO:0007026-&&-negative regulation of microtubule depolymerization|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0016234-&&-inclusion body-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030286-&&-dynein complex-%%-GO:0005771-&&-multivesicular body-%%-GO:0016235-&&-aggresome-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0031252-&&-cell leading edge-%%-GO:0043204-&&-perikaryon-%%-GO:0030424-&&-axon-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042903-&&-tubulin deacetylase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0048156-&&-tau protein binding	G:9606:HDAC6			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC6	0.47189591	0.0723008	230	4	FALSE	HDAC6	HDAC6	152.8245614	0	229	0	0.81348143	FALSE	1	HDAC6	3267008	0.02850018
787413	taxon:9606	2.14825902	9.49E-04	179475	1902	nucleolin	gene	biological_process-&-1&-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0001525-&&-angiogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:NCL			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection	NCL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCL	0.46549322	0.14533546	229	4	FALSE	NCL	NCL	196.3964758	0	228	0	0.8086235	FALSE	1	NCL	2185866	0.03787051
790676	taxon:9606	2.32865921	0.00176198	171510	1902	mediator complex subunit 4	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED4			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED4	0.42943166	0.04566	229	4	FALSE	MED4	MED4	73.69868996	0	229	0	0.7785568	FALSE	0	MED4	1951122	0.01826072
792563	taxon:9606	2.18528439	0.00220057	181811	1902	Cbl proto-oncogene	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0061024-&&-membrane organization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070997-&&-neuron death-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042594-&&-response to starvation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033574-&&-response to testosterone-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0008584-&&-male gonad development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity|cellular_component-&-1&-GO:0016600-&&-flotillin complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0005634-&&-nucleus-%%-GO:0042629-&&-mast cell granule-%%-GO:0045121-&&-membrane raft-%%-GO:0030424-&&-axon-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:CBL			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBL	0.45760634	0.08759892	229	4	FALSE	CBL	CBL	117.6740088	0	228	0	0.8024526	FALSE	1	CBL	2962578	0.02377075
787127	taxon:9606	2.22845439	8.25E-04	180016	1902	interleukin enhancer binding factor 2	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:1904724-&&-tertiary granule lumen-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005730-&&-nucleolus-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016740-&&-transferase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ILF2				ILF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILF2	0.44874152	0.16615337	227	4	FALSE	ILF2	ILF2	171.6563877	0	227	0	0.7952576	FALSE	0	ILF2	1637826	0.03667683
787400	taxon:9606	2.17472822	5.73E-04	179493	1902	heterogeneous nuclear ribonucleoprotein M	gene	biological_process-&-1&-GO:0010467-&&-gene expression-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPM			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPM	0.45982757	0.17909633	227	4	FALSE	HNRNPM	HNRNPM	184.1762115	0	227	0	0.80421196	FALSE	0	HNRNPM	1502842	0.03670311
793279	taxon:9606	2.20151253	0.0011437	180380	1902	H2A histone family member X	gene	biological_process-&-1&-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0090398-&&-cellular senescence-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0016032-&&-viral process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0000077-&&-DNA damage checkpoint|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005657-&&-replication fork-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0001741-&&-XY body-%%-GO:0005634-&&-nucleus-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:H2AFX			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	H2AFX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H2AFX	0.45423316	0.10626984	227	4	FALSE	H2AFX	H2AFX	159.5066667	0	226	0	0.79974791	FALSE	1	H2AFX	2145294	0.03290466
788265	taxon:9606	2.18764771	9.87E-04	177975	1902	ribosomal protein S2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0051347-&&-positive regulation of transferase activity-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS2			KEGG-&-1&-hsa03010-&&-Ribosome	RPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS2	0.45711199	0.25242871	226	4	FALSE	RPS2	RPS2	183.2212389	0	226	0	0.80205872	FALSE	0	RPS2	1812592	0.03707341
788520	taxon:9606	2.18323617	0.00216205	177515	1902	Sp1 transcription factor	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0100057-&&-regulation of phenotypic switching by transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048511-&&-rhythmic process-%%-GO:0016032-&&-viral process-%%-GO:1904828-&&-positive regulation of hydrogen sulfide biosynthetic process-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding	G:9606:SP1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05016-&&-Huntington disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04915-&&-Estrogen signaling pathway	SP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP1	0.45803565	0.07971653	226	4	FALSE	SP1	SP1	123.5803571	0	225	0	0.80279397	FALSE	1	SP1	2947112	0.02488131
788906	taxon:9606	2.16874114	5.34E-04	176633	1902	histone cluster 1 H4 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4B			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4B	0.46109699	0.12361849	226	4	FALSE	HIST1H4B	HIST1H4B	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4B	2681022	0.03645346
788907	taxon:9606	2.16874114	5.34E-04	176632	1902	histone cluster 1 H4 family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4E			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4E	0.46109699	0.12361849	226	4	FALSE	HIST1H4E	HIST1H4E	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4E	2681022	0.03645346
788908	taxon:9606	2.16874114	5.34E-04	176635	1902	histone cluster 1 H4 family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4C			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4C	0.46109699	0.12361849	226	4	FALSE	HIST1H4C	HIST1H4C	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4C	2681022	0.03645346
788909	taxon:9606	2.16874114	5.34E-04	176634	1902	histone cluster 1 H4 family member h	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4H			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4H	0.46109699	0.12361849	226	4	FALSE	HIST1H4H	HIST1H4H	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4H	2681022	0.03645346
788910	taxon:9606	2.16874114	5.34E-04	176629	1902	histone cluster 2 H4 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H4A			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H4A	0.46109699	0.12361849	226	4	FALSE	HIST2H4A	HIST2H4A	184.3495575	0	226	0	0.80520981	FALSE	0	HIST2H4A	2681022	0.03645346
788911	taxon:9606	2.16874114	5.34E-04	176631	1902	histone cluster 1 H4 family member l	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4L			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4L	0.46109699	0.12361849	226	4	FALSE	HIST1H4L	HIST1H4L	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4L	2681022	0.03645346
789032	taxon:9606	2.16874114	5.34E-04	176320	1902	histone cluster 1 H4 family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4I			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4I	0.46109699	0.12361849	226	4	FALSE	HIST1H4I	HIST1H4I	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4I	2681022	0.03645346
789196	taxon:9606	2.16874114	5.34E-04	176024	1902	histone cluster 1 H4 family member a	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4A			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4A	0.46109699	0.12361849	226	4	FALSE	HIST1H4A	HIST1H4A	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4A	2681022	0.03645346
789199	taxon:9606	2.16874114	5.34E-04	176021	1902	histone cluster 1 H4 family member k	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4K			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4K	0.46109699	0.12361849	226	4	FALSE	HIST1H4K	HIST1H4K	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4K	2681022	0.03645346
789200	taxon:9606	2.16874114	5.34E-04	176020	1902	histone cluster 1 H4 family member j	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4J			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4J	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4J	0.46109699	0.12361849	226	4	FALSE	HIST1H4J	HIST1H4J	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4J	2681022	0.03645346
789201	taxon:9606	2.16874114	5.34E-04	176023	1902	histone cluster 1 H4 family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4D			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4D	0.46109699	0.12361849	226	4	FALSE	HIST1H4D	HIST1H4D	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4D	2681022	0.03645346
789202	taxon:9606	2.16874114	5.34E-04	176022	1902	histone cluster 1 H4 family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST1H4F			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H4F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H4F	0.46109699	0.12361849	226	4	FALSE	HIST1H4F	HIST1H4F	184.3495575	0	226	0	0.80520981	FALSE	0	HIST1H4F	2681022	0.03645346
789656	taxon:9606	2.14951946	0.00178426	174967	1902	receptor for activated C kinase 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0043473-&&-pigmentation-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:2000543-&&-positive regulation of gastrulation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:1903208-&&-negative regulation of hydrogen peroxide-induced neuron death-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0051343-&&-positive regulation of cyclic-nucleotide phosphodiesterase activity-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:1900102-&&-negative regulation of endoplasmic reticulum unfolded protein response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0048511-&&-rhythmic process-%%-GO:0007369-&&-gastrulation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0006412-&&-translation-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0030822-&&-positive regulation of cAMP catabolic process-%%-GO:0051302-&&-regulation of cell division-%%-GO:0042998-&&-positive regulation of Golgi to plasma membrane protein transport-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0030425-&&-dendrite-%%-GO:0001891-&&-phagocytic cup-%%-GO:0030496-&&-midbody-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body-%%-GO:1990630-&&-IRE1-RACK1-PP2A complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0003723-&&-RNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0035591-&&-signaling adaptor activity-%%-GO:0008200-&&-ion channel inhibitor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0030292-&&-protein tyrosine kinase inhibitor activity	G:9606:RACK1			KEGG-&-1&-hsa05162-&&-Measles	RACK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RACK1	0.46522026	0.12471973	226	4	FALSE	RACK1	RACK1	186.2767857	0	225	0	0.80841342	FALSE	1	RACK1	3323436	0.03599293
790439	taxon:9606	2.16874114	5.34E-04	156594	1902	histone cluster 2 H4 family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H4B			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H4B	0.46109699	0.12361849	226	4	FALSE	HIST2H4B	HIST2H4B	184.3495575	0	226	0	0.80520981	FALSE	0	HIST2H4B	2681022	0.03645346
792626	taxon:9606	2.16874114	5.34E-04	165314	1902	histone cluster 4 H4	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0032200-&&-telomere organization-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016233-&&-telomere capping-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding	G:9606:HIST4H4			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST4H4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST4H4	0.46109699	0.12361849	226	4	FALSE	HIST4H4	HIST4H4	184.3495575	0	226	0	0.80520981	FALSE	0	HIST4H4	2681022	0.03645346
789861	taxon:9606	2.22089176	0.00172322	174492	1902	COP9 signalosome subunit 6	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0016032-&&-viral process-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS6				COPS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS6	0.45026958	0.0894437	225	4	FALSE	COPS6	COPS6	128.4170404	0	224	0	0.79651804	FALSE	1	COPS6	2442586	0.02713711
788868	taxon:9606	2.10950055	0.00185085	176729	1902	vimentin	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070307-&&-lens fiber cell development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0014002-&&-astrocyte development-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005882-&&-intermediate filament-%%-GO:0005777-&&-peroxisome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:1990254-&&-keratin filament binding-%%-GO:0042802-&&-identical protein binding	G:9606:VIM	VIM	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05206-&&-MicroRNAs in cancer	VIM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VIM	0.47404586	0.06351296	223	4	FALSE	VIM	VIM	157.081448	0	222	0	0.81508324	FALSE	1	VIM	3189184	0.02891978
790565	taxon:9606	2.17787931	8.11E-04	172127	1902	poly(A) binding protein cytoplasmic 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:2000623-&&-negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0006413-&&-translational initiation-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PABPC1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa03018-&&-RNA degradation	PABPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC1	0.45916227	0.16721514	223	4	FALSE	PABPC1	PABPC1	197.719457	0	222	0	0.80368678	FALSE	1	PABPC1	1850518	0.03949559
792684	taxon:9606	2.18969592	0.00129576	181561	1902	damage specific DNA binding protein 1	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0046726-&&-positive regulation by virus of viral protein levels in host cell-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0051702-&&-interaction with symbiont-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:DDB1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05161-&&-Hepatitis B	DDB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDB1	0.45668442	0.08502674	223	4	FALSE	DDB1	DDB1	160.8687783	0	222	0	0.80171735	FALSE	1	DDB1	2581868	0.03262213
788625	taxon:9606	2.23333859	0.00145724	177291	1902	telomeric repeat binding factor 1	gene	biological_process-&-1&-GO:0031627-&&-telomeric loop formation-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0051301-&&-cell division-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0090656-&&-t-circle formation-%%-GO:1905778-&&-negative regulation of exonuclease activity-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0016233-&&-telomere capping-%%-GO:1904850-&&-negative regulation of establishment of protein localization to telomere-%%-GO:0032214-&&-negative regulation of telomere maintenance via semi-conservative replication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1904792-&&-positive regulation of shelterin complex assembly-%%-GO:1905839-&&-negative regulation of telomeric D-loop disassembly-%%-GO:1904914-&&-negative regulation of establishment of macromolecular complex localization to telomere-%%-GO:0042493-&&-response to drug-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:1904911-&&-negative regulation of establishment of RNA localization to telomere-%%-GO:0000723-&&-telomere maintenance-%%-GO:0051974-&&-negative regulation of telomerase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0070187-&&-shelterin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001650-&&-fibrillar center-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003720-&&-telomerase activity-%%-GO:0071532-&&-ankyrin repeat binding-%%-GO:0008301-&&-DNA binding, bending	G:9606:TERF1				TERF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF1	0.44776014	0.04425073	222	4	FALSE	TERF1	TERF1	102.1590909	0	221	0	0.79444357	FALSE	1	TERF1	2074636	0.02193277
787583	taxon:9606	2.2371199	7.75E-04	179146	1902	neural precursor cell expressed, developmentally down-regulated 8	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0045116-&&-protein neddylation-%%-GO:0008104-&&-protein localization-%%-GO:0006508-&&-proteolysis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:NEDD8				NEDD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD8	0.44700331	0.12224038	221	4	FALSE	NEDD8	NEDD8	146.6118722	0	220	0	0.79381335	FALSE	1	NEDD8	1519266	0.03163731
788275	taxon:9606	2.21143847	4.75E-04	177961	1902	ribosomal protein S8	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS8			KEGG-&-1&-hsa03010-&&-Ribosome	RPS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS8	0.45219436	0.28062526	221	4	FALSE	RPS8	RPS8	192.4298643	0	221	0	0.79809359	FALSE	0	RPS8	1243238	0.0401481
787218	taxon:9606	2.26280132	0.00127021	179841	1902	mutated in colorectal cancers	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010633-&&-negative regulation of epithelial cell migration|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:MCC				MCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCC	0.44193009	0.03330401	219	4	FALSE	MCC	MCC	91.42922374	0	219	0	0.78953311	FALSE	0	MCC	1778078	0.02044122
792424	taxon:9606	2.1807153	0.003029	182047	1902	casein kinase 2 beta	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0006457-&&-protein folding-%%-GO:0097421-&&-liver regeneration-%%-GO:0007165-&&-signal transduction-%%-GO:0033574-&&-response to testosterone-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032927-&&-positive regulation of activin receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0051101-&&-regulation of DNA binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005929-&&-cilium-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000785-&&-chromatin-%%-GO:0005956-&&-protein kinase CK2 complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0031519-&&-PcG protein complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019887-&&-protein kinase regulator activity	G:9606:CSNK2B			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04520-&&-Adherens junction-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2B	0.45856513	0.0499232	219	4	FALSE	CSNK2B	CSNK2B	123.4654378	0	218	0	0.80321412	FALSE	1	CSNK2B	3671436	0.02481233
793215	taxon:9606	2.10398614	0.00126857	180519	1902	heat shock protein family A (Hsp70) member 1A	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0070434-&&-positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0042026-&&-protein refolding-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:1901029-&&-negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0034605-&&-cellular response to heat-%%-GO:1902380-&&-positive regulation of endoribonuclease activity-%%-GO:0010941-&&-regulation of cell death-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:1904722-&&-positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016234-&&-inclusion body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0044183-&&-protein binding involved in protein folding	G:9606:HSPA1A	HSPA1A	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1A	0.4752883	0.09635122	219	4	FALSE	HSPA1A	HSPA1A	179.8127854	0	219	0	0.81600231	FALSE	0	HSPA1A	2983846	0.03285969
793216	taxon:9606	2.10398614	0.00126857	180518	1902	heat shock protein family A (Hsp70) member 1B	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0070434-&&-positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0042026-&&-protein refolding-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010941-&&-regulation of cell death|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016234-&&-inclusion body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HSPA1B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1B	0.4752883	0.09635122	219	4	FALSE	HSPA1B	HSPA1B	179.8127854	0	219	0	0.81600231	FALSE	0	HSPA1B	2983846	0.03285969
788724	taxon:9606	2.18339373	0.00267797	177119	1902	TNF receptor associated factor 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:1903721-&&-positive regulation of I-kappaB phosphorylation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0030163-&&-protein catabolic process-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0071732-&&-cellular response to nitric oxide|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:1990597-&&-AIP1-IRE1 complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:1990604-&&-IRE1-TRAF2-ASK1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097057-&&-TRAF2-GSTP1 complex-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005174-&&-CD40 receptor binding-%%-GO:0046625-&&-sphingolipid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:TRAF2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	TRAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF2	0.4580026	0.06533161	218	4	FALSE	TRAF2	TRAF2	105.6111111	0	217	0	0.80276771	FALSE	1	TRAF2	3015152	0.02123411
792699	taxon:9606	2.17551599	5.86E-04	181545	1902	DExH-box helicase 9	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0048511-&&-rhythmic process-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule|cellular_component-&-1&-GO:0097165-&&-nuclear stress granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity	G:9606:DHX9				DHX9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX9	0.45966107	0.16326443	218	4	FALSE	DHX9	DHX9	194.7685185	0	217	0	0.80408067	FALSE	1	DHX9	1486368	0.03873678
787732	taxon:9606	2.20434851	0.00145375	178862	1902	RNA polymerase II subunit A	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0001172-&&-transcription, RNA-templated-%%-GO:0010467-&&-gene expression-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0000974-&&-Prp19 complex-%%-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003968-&&-RNA-directed 5'-3' RNA polymerase activity	G:9606:POLR2A			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2A	0.45364877	0.08611171	217	4	FALSE	POLR2A	POLR2A	140.1674419	0	216	0	0.79927525	FALSE	1	POLR2A	2389648	0.02888284
788794	taxon:9606	2.21632267	0.0029681	176882	1902	BCL2 associated athanogene 6	gene	biological_process-&-1&-GO:0007420-&&-brain development-%%-GO:0050821-&&-protein stabilization-%%-GO:0009790-&&-embryo development-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0071816-&&-tail-anchored membrane protein insertion into ER membrane-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:1904294-&&-positive regulation of ERAD pathway-%%-GO:0007130-&&-synaptonemal complex assembly-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030324-&&-lung development-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1904379-&&-protein localization to cytosolic proteasome complex involved in ERAD pathway-%%-GO:0006810-&&-transport-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0002429-&&-immune response-activating cell surface receptor signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:1904378-&&-maintenance of unfolded protein involved in ERAD pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0071818-&&-BAT3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0015643-&&-toxic substance binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0031593-&&-polyubiquitin binding	G:9606:BAG6				BAG6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG6	0.45119784	0.03403608	217	4	FALSE	BAG6	BAG6	97.02790698	0	216	0	0.79727955	FALSE	1	BAG6	3295106	0.02039409
789771	taxon:9606	2.1573972	0.00163006	174720	1902	tripartite motif containing 28	gene	biological_process-&-1&-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing-%%-GO:0045869-&&-negative regulation of single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0051259-&&-protein oligomerization-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0060669-&&-embryonic placenta morphogenesis-%%-GO:0007566-&&-embryo implantation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0060028-&&-convergent extension involved in axis elongation-%%-GO:1901536-&&-negative regulation of DNA demethylation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045087-&&-innate immune response-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:2000653-&&-regulation of genetic imprinting|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0035851-&&-Krueppel-associated box domain binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:TRIM28				TRIM28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM28	0.46352151	0.10113641	216	4	FALSE	TRIM28	TRIM28	195.1401869	0	215	0	0.80710047	FALSE	1	TRIM28	2912760	0.03795491
789068	taxon:9606	2.13407909	0.00170098	176248	1902	IQ motif containing GTPase activating protein 1	gene	biological_process-&-1&-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1903829-&&-positive regulation of cellular protein localization-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1990776-&&-response to angiotensin-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1900086-&&-positive regulation of peptidyl-tyrosine autophosphorylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007165-&&-signal transduction-%%-GO:1990138-&&-neuron projection extension-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0035305-&&-negative regulation of dephosphorylation-%%-GO:1900006-&&-positive regulation of dendrite development|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005884-&&-actin filament-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0036057-&&-slit diaphragm-%%-GO:0001726-&&-ruffle-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0043234-&&-protein complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft-%%-GO:0043005-&&-neuron projection-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:IQGAP1			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction	IQGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQGAP1	0.46858619	0.10758531	215	4	FALSE	IQGAP1	IQGAP1	155.9116279	0	215	0	0.81098682	FALSE	0	IQGAP1	2676824	0.02950548
790172	taxon:9606	2.2256184	0.0026399	173719	1902	lysine demethylase 1A	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0055001-&&-muscle cell development-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0060992-&&-response to fungicide-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0010725-&&-regulation of primitive erythrocyte differentiation-%%-GO:0033184-&&-positive regulation of histone ubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1990138-&&-neuron projection extension-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0007596-&&-blood coagulation-%%-GO:0021983-&&-pituitary gland development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045654-&&-positive regulation of megakaryocyte differentiation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0034720-&&-histone H3-K4 demethylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046098-&&-guanine metabolic process-%%-GO:0006482-&&-protein demethylation-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0042551-&&-neuron maturation-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0071320-&&-cellular response to cAMP|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990391-&&-DNA repair complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0032451-&&-demethylase activity-%%-GO:0032453-&&-histone demethylase activity (H3-K4 specific)-%%-GO:0034648-&&-histone demethylase activity (H3-dimethyl-K4 specific)-%%-GO:0043426-&&-MRF binding-%%-GO:0061752-&&-telomeric repeat-containing RNA binding-%%-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0002039-&&-p53 binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding	G:9606:KDM1A			KEGG-&-1&-hsa04714-&&-Thermogenesis	KDM1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM1A	0.44931332	0.06758792	215	4	FALSE	KDM1A	KDM1A	127.4694836	0	214	0	0.79573027	FALSE	1	KDM1A	3460576	0.02705162
788045	taxon:9606	2.20340318	4.50E-04	178309	1902	ribosomal protein L6	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL6			KEGG-&-1&-hsa03010-&&-Ribosome	RPL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL6	0.4538434	0.29827564	214	4	FALSE	RPL6	RPL6	193.5560748	0	214	0	0.7994328	FALSE	0	RPL6	1124898	0.03989832
788266	taxon:9606	2.17693398	3.55E-04	177974	1902	ribosomal protein S3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006412-&&-translation-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0051225-&&-spindle assembly-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0061481-&&-response to TNF agonist-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0045738-&&-negative regulation of DNA repair-%%-GO:0007059-&&-chromosome segregation-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1902546-&&-positive regulation of DNA N-glycosylase activity-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1905053-&&-positive regulation of base-excision repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006413-&&-translational initiation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006979-&&-response to oxidative stress-%%-GO:2001272-&&-positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005840-&&-ribosome-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0032358-&&-oxidized pyrimidine DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019900-&&-kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0051536-&&-iron-sulfur cluster binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0044390-&&-ubiquitin-like protein conjugating enzyme binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0070181-&&-small ribosomal subunit rRNA binding-%%-GO:0032183-&&-SUMO binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0015631-&&-tubulin binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0097100-&&-supercoiled DNA binding	G:9606:RPS3			KEGG-&-1&-hsa03010-&&-Ribosome	RPS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS3	0.45936166	0.29305428	214	4	FALSE	RPS3	RPS3	203.228972	0	214	0	0.80384434	FALSE	0	RPS3	1214694	0.04051614
788800	taxon:9606	2.13770285	0.00121386	176847	1902	tubulin gamma 1	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0000212-&&-meiotic spindle organization|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0097730-&&-non-motile cilium-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0031252-&&-cell leading edge-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0055037-&&-recycling endosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005827-&&-polar microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding	G:9606:TUBG1			KEGG-&-1&-hsa05165-&&-Human papillomavirus infection	TUBG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBG1	0.46779186	0.11629259	214	4	FALSE	TUBG1	TUBG1	165.004717	0	213	0	0.81038286	FALSE	1	TUBG1	2100290	0.03133814
789691	taxon:9606	2.17378289	0.00141089	174884	1902	synaptotagmin binding cytoplasmic RNA interacting protein	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006396-&&-RNA processing-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0016032-&&-viral process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0097452-&&-GAIT complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SYNCRIP				SYNCRIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNCRIP	0.46002754	0.11759028	214	4	FALSE	SYNCRIP	SYNCRIP	170.7570094	0	214	0	0.80436952	FALSE	0	SYNCRIP	2381128	0.0339247
792694	taxon:9606	2.14053884	8.97E-04	181549	1902	DEAD-box helicase 5	gene	biological_process-&-1&-GO:0045069-&&-regulation of viral genome replication-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009299-&&-mRNA transcription-%%-GO:0048511-&&-rhythmic process-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0016049-&&-cell growth-%%-GO:0045667-&&-regulation of osteoblast differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0003724-&&-RNA helicase activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0036002-&&-pre-mRNA binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX5			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa03040-&&-Spliceosome	DDX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX5	0.46717209	0.14249307	214	4	FALSE	DDX5	DDX5	199.6462264	0	213	0	0.80991019	FALSE	1	DDX5	2018628	0.03806141
787869	taxon:9606	2.18103041	0.0015104	178669	1902	proteasome subunit alpha 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0052548-&&-regulation of endopeptidase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005839-&&-proteasome core complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA3			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA3	0.45849888	0.11293162	213	4	FALSE	PSMA3	PSMA3	136.7251185	0	212	0	0.8031616	FALSE	1	PSMA3	2089650	0.02743621
788470	taxon:9606	2.19946431	0.00113896	177582	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0003407-&&-neural retina development-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006325-&&-chromatin organization-%%-GO:1902661-&&-positive regulation of glucose mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007399-&&-nervous system development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007070-&&-negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0071564-&&-npBAF complex-%%-GO:0071565-&&-nBAF complex-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0004386-&&-helicase activity-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0030957-&&-Tat protein binding	G:9606:SMARCA4			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA4	0.45465616	0.12872941	213	4	FALSE	SMARCA4	SMARCA4	165.2227488	0	212	0	0.80008928	FALSE	1	SMARCA4	2268096	0.03382247
790074	taxon:9606	2.29383961	7.98E-04	173937	1902	centrosomal protein 250	gene	biological_process-&-1&-GO:0030997-&&-regulation of centriole-centriole cohesion-%%-GO:0008104-&&-protein localization-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:1904781-&&-positive regulation of protein localization to centrosome|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0005814-&&-centriole-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CEP250				CEP250	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP250	0.43595027	0.10600912	212	4	FALSE	CEP250	CEP250	137.1462264	0	212	0	0.78436007	FALSE	0	CEP250	1542388	0.03201753
793177	taxon:9606	2.22861194	0.00110475	180582	1902	stratifin	gene	biological_process-&-1&-GO:0045606-&&-positive regulation of epidermal cell differentiation-%%-GO:0061024-&&-membrane organization-%%-GO:0031424-&&-keratinization-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0003334-&&-keratinocyte development-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0010482-&&-regulation of epidermal cell division|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008426-&&-protein kinase C inhibitor activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding	G:9606:SFN			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	SFN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFN	0.44870979	0.07691957	212	4	FALSE	SFN	SFN	124.8428571	0	211	0	0.79523134	FALSE	1	SFN	1733098	0.02654334
787575	taxon:9606	2.21569245	0.00234499	179149	1902	neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0031175-&&-neuron projection development-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0046824-&&-positive regulation of nucleocytoplasmic transport-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0050807-&&-regulation of synapse organization-%%-GO:0051592-&&-response to calcium ion-%%-GO:0044111-&&-development involved in symbiotic interaction-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010768-&&-negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0007041-&&-lysosomal transport-%%-GO:0002250-&&-adaptive immune response-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0010766-&&-negative regulation of sodium ion transport-%%-GO:0019089-&&-transmission of virus-%%-GO:0031623-&&-receptor internalization-%%-GO:0042110-&&-T cell activation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043197-&&-dendritic spine-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000785-&&-chromatin-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019871-&&-sodium channel inhibitor activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0050815-&&-phosphoserine binding	G:9606:NEDD4			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04530-&&-Tight junction	NEDD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD4	0.45132618	0.04016378	211	4	FALSE	NEDD4	NEDD4	102.0382775	0	210	0	0.79738459	FALSE	1	NEDD4	2743946	0.02140503
787755	taxon:9606	2.33385852	9.20E-04	178833	1902	POU class 5 homeobox 1	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0009786-&&-regulation of asymmetric cell division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0009611-&&-response to wounding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0001824-&&-blastocyst development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:POU5F1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	POU5F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1	0.42847499	0.05148141	211	4	FALSE	POU5F1	POU5F1	91.54066986	0	210	0	0.77769025	FALSE	1	POU5F1	1851794	0.0225859
790431	taxon:9606	2.33385852	9.20E-04	156622	1902	POU class 5 homeobox 1 pseudogene 3	gene		G:9606:POU5F1P3				POU5F1P3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1P3	0.42847499	0.05148141	211	4	FALSE	POU5F1P3	POU5F1P3	91.54066986	0	210	0	0.77769025	FALSE	1	POU5F1P3	1851794	0.0225859
790602	taxon:9606	2.33385852	9.20E-04	155470	1902	POU class 5 homeobox 1 pseudogene 4	gene		G:9606:POU5F1P4				POU5F1P4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU5F1P4	0.42847499	0.05148141	211	4	FALSE	POU5F1P4	POU5F1P4	91.54066986	0	210	0	0.77769025	FALSE	1	POU5F1P4	1851794	0.0225859
792844	taxon:9606	2.22325508	0.00261432	181273	1902	erb-b2 receptor tyrosine kinase 2	gene	biological_process-&-1&-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0033088-&&-negative regulation of immature T cell proliferation in thymus-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0042060-&&-wound healing-%%-GO:0042552-&&-myelination-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001042-&&-RNA polymerase I core binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:ERBB2	ERBB2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04530-&&-Tight junction-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05226-&&-Gastric cancer	ERBB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB2	0.44979094	0.05309165	211	4	FALSE	ERBB2	ERBB2	89.86602871	0	210	0	0.79612415	FALSE	1	ERBB2	2729274	0.01902426
788895	taxon:9606	2.16905625	0.00104625	176657	1902	X-ray repair cross complementing 5	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0006310-&&-DNA recombination-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0008283-&&-cell proliferation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071475-&&-cellular hyperosmotic salinity response-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:1904430-&&-negative regulation of t-circle formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0007420-&&-brain development-%%-GO:0006302-&&-double-strand break repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0043564-&&-Ku70:Ku80 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0070419-&&-nonhomologous end joining complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0051575-&&-5'-deoxyribose-5-phosphate lyase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:XRCC5			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	XRCC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC5	0.46103	0.1104608	210	4	FALSE	XRCC5	XRCC5	182.5769231	0	209	0	0.80515729	FALSE	1	XRCC5	2295506	0.03600743
787132	taxon:9606	2.20387585	0.0013877	180014	1902	integrin linked kinase	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0070527-&&-platelet aggregation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0034329-&&-cell junction assembly-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0021675-&&-nerve development-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0032288-&&-myelin assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0010761-&&-fibroblast migration-%%-GO:0008283-&&-cell proliferation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007569-&&-cell aging-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0097435-&&-supramolecular fiber organization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043034-&&-costamere-%%-GO:0043195-&&-terminal bouton-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0001725-&&-stress fiber-%%-GO:0030017-&&-sarcomere|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004871-&&-signal transducer activity	G:9606:ILK	ILK	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05213-&&-Endometrial cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa03320-&&-PPAR signaling pathway	ILK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILK	0.45374607	0.05121711	209	4	FALSE	ILK	ILK	115.3719807	0	208	0	0.79935403	FALSE	1	ILK	1944432	0.02380069
789079	taxon:9606	2.21301402	0.00112861	176234	1902	histone deacetylase 3	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006476-&&-protein deacetylation-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051225-&&-spindle assembly-%%-GO:0006325-&&-chromatin organization-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0010832-&&-negative regulation of myotube differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0019899-&&-enzyme binding	G:9606:HDAC3	HDAC3	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC3	0.45187242	0.12063224	209	4	FALSE	HDAC3	HDAC3	148.9661836	0	208	0	0.797831	FALSE	1	HDAC3	2129850	0.03103462
790365	taxon:9606	2.20497873	8.25E-04	173214	1902	serine/arginine repetitive matrix 2	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:SRRM2				SRRM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRM2	0.45351911	0.15646853	209	4	FALSE	SRRM2	SRRM2	176.6507177	0	209	0	0.79917021	FALSE	0	SRRM2	1626916	0.0364434
787544	taxon:9606	2.16448716	0.00174837	179218	1902	protein phosphatase 2 scaffold subunit Aalpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0051306-&&-mitotic sister chromatid separation-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0010033-&&-response to organic substance-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051232-&&-meiotic spindle elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0019932-&&-second-messenger-mediated signaling-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006915-&&-apoptotic process-%%-GO:0007143-&&-female meiotic division-%%-GO:0040008-&&-regulation of growth-%%-GO:1903538-&&-regulation of meiotic cell cycle process involved in oocyte maturation-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005634-&&-nucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003823-&&-antigen binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:PPP2R1A			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R1A	0.4620032	0.07738759	208	4	FALSE	PPP2R1A	PPP2R1A	146.9615385	0	208	0	0.80591881	FALSE	0	PPP2R1A	2654446	0.02882635
787716	taxon:9606	2.15188278	0.00157552	178894	1902	promyelocytic leukemia	gene	biological_process-&-1&-GO:0030155-&&-regulation of cell adhesion-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0010332-&&-response to gamma radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0090398-&&-cellular senescence-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0010522-&&-regulation of calcium ion transport into cytosol-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030578-&&-PML body organization-%%-GO:0034097-&&-response to cytokine-%%-GO:0045087-&&-innate immune response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0010761-&&-fibroblast migration-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0050713-&&-negative regulation of interleukin-1 beta secretion-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0009411-&&-response to UV-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2000779-&&-regulation of double-strand break repair-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042406-&&-extrinsic component of endoplasmic reticulum membrane-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032183-&&-SUMO binding	G:9606:PML			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05164-&&-Influenza A	PML	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PML	0.46470933	0.08493544	207	4	FALSE	PML	PML	143.4243902	0	206	0	0.80801954	FALSE	1	PML	2503876	0.02762223
793362	taxon:9606	2.16291161	0.00164448	180239	1902	heterogeneous nuclear ribonucleoprotein D	gene	biological_process-&-1&-GO:0097167-&&-circadian regulation of translation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0021549-&&-cerebellum development-%%-GO:1901355-&&-response to rapamycin-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905663-&&-positive regulation of telomerase RNA reverse transcriptase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0001889-&&-liver development-%%-GO:1990828-&&-hepatocyte dedifferentiation-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0010467-&&-gene expression-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904586-&&-cellular response to putrescine-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006396-&&-RNA processing-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:1904383-&&-response to sodium phosphate|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:HNRNPD				HNRNPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPD	0.46233974	0.11487327	207	4	FALSE	HNRNPD	HNRNPD	167.1804878	0	206	0	0.8061814	FALSE	1	HNRNPD	2460094	0.03272533
789699	taxon:9606	2.16889869	0.00167604	174861	1902	lysine acetyltransferase 5	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006302-&&-double-strand break repair-%%-GO:1901985-&&-positive regulation of protein acetylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0040008-&&-regulation of growth-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0016573-&&-histone acetylation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0000732-&&-strand displacement-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032703-&&-negative regulation of interleukin-2 production|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0032777-&&-Piccolo NuA4 histone acetyltransferase complex-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0050681-&&-androgen receptor binding	G:9606:KAT5			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	KAT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT5	0.46106349	0.10059886	206	4	FALSE	KAT5	KAT5	155.8970588	0	205	0	0.80518355	FALSE	1	KAT5	2789656	0.03070582
790018	taxon:9606	2.14022373	0.00107016	174088	1902	RuvB like AAA ATPase 2	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006457-&&-protein folding-%%-GO:0071733-&&-transcriptional activation by promoter-enhancer looping-%%-GO:0071899-&&-negative regulation of estrogen receptor binding-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006310-&&-DNA recombination-%%-GO:0040008-&&-regulation of growth-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0097255-&&-R2TP complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000812-&&-Swr1 complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005829-&&-cytosol-%%-GO:0031011-&&-Ino80 complex-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0043531-&&-ADP binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043141-&&-ATP-dependent 5'-3' DNA helicase activity	G:9606:RUVBL2				RUVBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUVBL2	0.46724087	0.10510657	205	4	FALSE	RUVBL2	RUVBL2	184.3349754	0	204	0	0.80996271	FALSE	1	RUVBL2	2297982	0.03504467
793222	taxon:9606	2.09752639	0.00151093	180510	1902	heat shock protein family A (Hsp70) member 9	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:1902037-&&-negative regulation of hematopoietic stem cell differentiation-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HSPA9			KEGG-&-1&-hsa05152-&&-Tuberculosis-%%-hsa03018-&&-RNA degradation	HSPA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA9	0.47675205	0.10301291	205	4	FALSE	HSPA9	HSPA9	196.1853659	0	205	0	0.81707893	FALSE	0	HSPA9	2900026	0.03550778
787832	taxon:9606	2.1573972	0.00329437	178737	1902	mitogen-activated protein kinase 8	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0031063-&&-regulation of histone deacetylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0048666-&&-neuron development-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0007254-&&-JNK cascade-%%-GO:0031281-&&-positive regulation of cyclase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009411-&&-response to UV-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0048511-&&-rhythmic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0090045-&&-positive regulation of deacetylase activity-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004705-&&-JUN kinase activity-%%-GO:0035033-&&-histone deacetylase regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding	G:9606:MAPK8	MAPK8	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8	0.46352151	0.05797744	204	4	FALSE	MAPK8	MAPK8	111.7623762	0	203	0	0.80710047	FALSE	1	MAPK8	3456186	0.02170483
788162	taxon:9606	2.2851741	0.00125321	178140	1902	RAD21 cohesin complex component	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045876-&&-positive regulation of sister chromatid cohesion-%%-GO:0006915-&&-apoptotic process-%%-GO:0006302-&&-double-strand break repair-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0000798-&&-nuclear cohesin complex-%%-GO:0000785-&&-chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008278-&&-cohesin complex-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:RAD21			KEGG-&-1&-hsa04110-&&-Cell cycle	RAD21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD21	0.43760342	0.10509031	204	4	FALSE	RAD21	RAD21	152.3480392	0	204	0	0.78580432	FALSE	0	RAD21	2234592	0.03506883
789031	taxon:9606	2.28879786	8.71E-04	176324	1902	histone cluster 3 H3	gene	biological_process-&-1&-GO:0016233-&&-telomere capping-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0032460-&&-negative regulation of protein oligomerization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000786-&&-nucleosome-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST3H3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST3H3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST3H3	0.43691058	0.11812226	204	4	FALSE	HIST3H3	HIST3H3	129.0247525	0	203	0	0.78520036	FALSE	1	HIST3H3	1647276	0.02976007
793089	taxon:9606	2.08003781	0.00200382	180754	1902	glyceraldehyde-3-phosphate dehydrogenase	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0050821-&&-protein stabilization-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0035606-&&-peptidyl-cysteine S-trans-nitrosylation-%%-GO:0051402-&&-neuron apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0097452-&&-GAIT complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004365-&&-glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0051287-&&-NAD binding-%%-GO:0050661-&&-NADP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035605-&&-peptidyl-cysteine S-nitrosylase activity	G:9606:GAPDH	GAPDH	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	GAPDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAPDH	0.48076049	0.10896015	204	4	FALSE	GAPDH	GAPDH	192.7574257	0	203	0	0.8199937	FALSE	1	GAPDH	3237558	0.03418291
787437	taxon:9606	2.45879943	0.0019785	163058	1902	transmembrane protein 17	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:1905515-&&-non-motile cilium assembly|cellular_component-&-1&-GO:0035869-&&-ciliary transition zone-%%-GO:0016021-&&-integral component of membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0036038-&&-MKS complex	G:9606:TMEM17				TMEM17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM17	0.40670255	0.01339835	202	4	FALSE	TMEM17	TMEM17	44.86138614	0	202	0	0.75686676	FALSE	0	TMEM17	1912852	0.01393061
787681	taxon:9606	2.18812037	0.00170573	178960	1902	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	gene	biological_process-&-1&-GO:0050808-&&-synapse organization-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060393-&&-regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007049-&&-cell cycle-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0030182-&&-neuron differentiation-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0032794-&&-GTPase activating protein binding-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0050815-&&-phosphoserine binding-%%-GO:0003774-&&-motor activity-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PIN1			KEGG-&-1&-hsa04622-&&-RIG-I-like receptor signaling pathway	PIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIN1	0.45701325	0.05597015	201	4	FALSE	PIN1	PIN1	125.6318408	0	201	0	0.80197994	FALSE	0	PIN1	2473994	0.0253342
787894	taxon:9606	2.19190169	0.00155982	178645	1902	proteasome 26S subunit, non-ATPase 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD2			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD2	0.45622484	0.11578092	201	4	FALSE	PSMD2	PSMD2	147.5326633	0	200	0	0.80134972	FALSE	1	PSMD2	2351578	0.02983973
788028	taxon:9606	2.22420041	0.00132792	178360	1902	ATP binding cassette subfamily E member 1	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006413-&&-translational initiation-%%-GO:0060702-&&-negative regulation of endoribonuclease activity-%%-GO:0006415-&&-translational termination-%%-GO:0016032-&&-viral process-%%-GO:0000054-&&-ribosomal subunit export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0060698-&&-endoribonuclease inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:ABCE1				ABCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCE1	0.44959977	0.05035277	201	4	FALSE	ABCE1	ABCE1	118.0201005	0	200	0	0.7959666	FALSE	1	ABCE1	1939864	0.02493239
790150	taxon:9606	2.25949267	0.00153584	173760	1902	PAX interacting protein 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0000416-&&-positive regulation of histone H3-K36 methylation-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0006310-&&-DNA recombination-%%-GO:0060717-&&-chorion development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PAXIP1				PAXIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAXIP1	0.44257723	0.06084577	201	4	FALSE	PAXIP1	PAXIP1	116.4925373	0	201	0	0.79008455	FALSE	0	PAXIP1	2166014	0.02589122
793228	taxon:9606	2.1128092	0.00175319	180499	1902	heat shock protein family D (Hsp60) member 1	gene	biological_process-&-1&-GO:0051604-&&-protein maturation-%%-GO:0002368-&&-B cell cytokine production-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0043627-&&-response to estrogen-%%-GO:0016032-&&-viral process-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0002931-&&-response to ischemia-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0002236-&&-detection of misfolded protein-%%-GO:0009408-&&-response to heat-%%-GO:0050821-&&-protein stabilization-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033198-&&-response to ATP-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0009409-&&-response to cold-%%-GO:0042220-&&-response to cocaine-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0001666-&&-response to hypoxia-%%-GO:0042113-&&-B cell activation-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0045041-&&-protein import into mitochondrial intermembrane space-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042026-&&-protein refolding-%%-GO:0071866-&&-negative regulation of apoptotic process in bone marrow-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0014823-&&-response to activity-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:1903427-&&-negative regulation of reactive oxygen species biosynthetic process-%%-GO:1904469-&&-positive regulation of tumor necrosis factor secretion-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0002842-&&-positive regulation of T cell mediated immune response to tumor cell-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0048291-&&-isotype switching to IgG isotypes-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0042110-&&-T cell activation-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030061-&&-mitochondrial crista-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030141-&&-secretory granule-%%-GO:0030135-&&-coated vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0042588-&&-zymogen granule-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0002039-&&-p53 binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0043559-&&-insulin binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:HSPD1			KEGG-&-1&-hsa04940-&&-Type I diabetes mellitus-%%-hsa05152-&&-Tuberculosis-%%-hsa05134-&&-Legionellosis-%%-hsa03018-&&-RNA degradation	HSPD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPD1	0.4733035	0.09740622	201	4	FALSE	HSPD1	HSPD1	198.5527638	0	200	0	0.8145318	FALSE	1	HSPD1	3332078	0.036542
787451	taxon:9606	2.20939026	8.74E-04	179405	1902	mitogen-activated protein kinase kinase kinase 3	gene	biological_process-&-1&-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001568-&&-blood vessel development-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MAP3K3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04912-&&-GnRH signaling pathway	MAP3K3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K3	0.45261356	0.08039789	200	4	FALSE	MAP3K3	MAP3K3	146.489899	0	199	0	0.79843496	FALSE	1	MAP3K3	1649818	0.03035851
788969	taxon:9606	2.26028045	6.02E-04	176514	1902	ribosomal protein L14	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL14			KEGG-&-1&-hsa03010-&&-Ribosome	RPL14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL14	0.44242298	0.29557789	200	4	FALSE	RPL14	RPL14	185.58	0	200	0	0.78995326	FALSE	0	RPL14	1240820	0.04109967
792387	taxon:9606	2.20466362	0.00162913	182110	1902	activating transcription factor 2	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0016573-&&-histone acetylation-%%-GO:1902110-&&-positive regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0032915-&&-positive regulation of transforming growth factor beta2 production-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0097186-&&-amelogenesis-%%-GO:0009414-&&-response to water deprivation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006970-&&-response to osmotic stress|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008140-&&-cAMP response element binding protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:ATF2			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF2	0.45358393	0.05686305	200	4	FALSE	ATF2	ATF2	112.5808081	0	199	0	0.79922273	FALSE	1	ATF2	2268748	0.02320587
787183	taxon:9606	2.2204191	0.0022272	179908	1902	SMAD family member 4	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0007492-&&-endoderm development-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0048859-&&-formation of anatomical boundary-%%-GO:1905305-&&-negative regulation of cardiac myofibril assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0060956-&&-endocardial cell differentiation-%%-GO:0051098-&&-regulation of binding-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0014033-&&-neural crest cell differentiation-%%-GO:0007411-&&-axon guidance-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0048589-&&-developmental growth-%%-GO:0072134-&&-nephrogenic mesenchyme morphogenesis-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007498-&&-mesoderm development-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0032525-&&-somite rostral/caudal axis specification-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072133-&&-metanephric mesenchyme morphogenesis-%%-GO:0003251-&&-positive regulation of cell proliferation involved in heart valve morphogenesis-%%-GO:0003190-&&-atrioventricular valve formation-%%-GO:0003220-&&-left ventricular cardiac muscle tissue morphogenesis-%%-GO:0051797-&&-regulation of hair follicle development-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0061040-&&-female gonad morphogenesis-%%-GO:0003360-&&-brainstem development-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0046881-&&-positive regulation of follicle-stimulating hormone secretion-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0060065-&&-uterus development-%%-GO:0008283-&&-cell proliferation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060021-&&-palate development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048733-&&-sebaceous gland development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007338-&&-single fertilization-%%-GO:0033686-&&-positive regulation of luteinizing hormone secretion-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0071773-&&-cellular response to BMP stimulus|cellular_component-&-1&-GO:0071141-&&-SMAD protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0032444-&&-activin responsive factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000988-&&-transcription factor activity, protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0005518-&&-collagen binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0030616-&&-transforming growth factor beta receptor, common-partner cytoplasmic mediator activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:SMAD4	SMAD4	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SMAD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD4	0.45036543	0.06324459	199	4	FALSE	SMAD4	SMAD4	107.8984772	0	198	0	0.79659682	FALSE	1	SMAD4	2649122	0.02271435
787538	taxon:9606	2.14747125	0.00176139	179221	1902	protein phosphatase 2 catalytic subunit alpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0007498-&&-mesoderm development-%%-GO:0040008-&&-regulation of growth-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0008380-&&-RNA splicing-%%-GO:0010033-&&-response to organic substance-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0019932-&&-second-messenger-mediated signaling-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0050811-&&-GABA receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding	G:9606:PPP2CA			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04136-&&-Autophagy - other-%%-hsa03015-&&-mRNA surveillance pathway	PPP2CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2CA	0.46566398	0.08370133	199	4	FALSE	PPP2CA	PPP2CA	145.6884422	0	199	0	0.80875479	FALSE	0	PPP2CA	2569006	0.02792818
787604	taxon:9606	2.18859304	0.00147152	179114	1902	nuclear factor kappa B subunit 1	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:1900127-&&-positive regulation of hyaluronan biosynthetic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0045083-&&-negative regulation of interleukin-12 biosynthetic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0032375-&&-negative regulation of cholesterol transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0010956-&&-negative regulation of calcidiol 1-monooxygenase activity-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071359-&&-cellular response to dsRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0035994-&&-response to muscle stretch|cellular_component-&-1&-GO:0035580-&&-specific granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000975-&&-regulatory region DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042805-&&-actinin binding	G:9606:NFKB1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05140-&&-Leishmaniasis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05134-&&-Legionellosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	NFKB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKB1	0.45691455	0.08800373	199	4	FALSE	NFKB1	NFKB1	136.2741117	0	198	0	0.80190116	FALSE	1	NFKB1	2215632	0.0275073
788047	taxon:9606	2.20860249	4.01E-04	178311	1902	ribosomal protein L5	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008097-&&-5S rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL5			KEGG-&-1&-hsa03010-&&-Ribosome	RPL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL5	0.452775	0.31819124	199	4	FALSE	RPL5	RPL5	192.6497462	0	198	0	0.79856625	FALSE	1	RPL5	1065554	0.03983659
788475	taxon:9606	2.25492359	0.0012749	177573	1902	survival of motor neuron 2, centromeric	gene	biological_process-&-1&-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0007399-&&-nervous system development-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0043005-&&-neuron projection-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SMN2			KEGG-&-1&-hsa03013-&&-RNA transport	SMN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMN2	0.44347401	0.07992334	199	4	FALSE	SMN2	SMN2	132.2538071	0	198	0	0.79084607	FALSE	1	SMN2	2342218	0.02904762
788477	taxon:9606	2.25492359	0.0012749	177574	1902	survival of motor neuron 1, telomeric	gene	biological_process-&-1&-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0007399-&&-nervous system development-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0043005-&&-neuron projection-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SMN1			KEGG-&-1&-hsa03013-&&-RNA transport	SMN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMN1	0.44347401	0.07992334	199	4	FALSE	SMN1	SMN1	132.2538071	0	198	0	0.79084607	FALSE	1	SMN1	2342218	0.02904762
789702	taxon:9606	2.33968804	5.00E-04	174857	1902	NOP56 ribonucleoprotein	gene	biological_process-&-1&-GO:0000154-&&-rRNA modification-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex-%%-GO:0032040-&&-small-subunit processome-%%-GO:0070761-&&-pre-snoRNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:NOP56			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NOP56	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP56	0.42740741	0.1925283	199	4	FALSE	NOP56	NOP56	139.2110553	0	199	0	0.77671866	FALSE	0	NOP56	894450	0.03462712
792263	taxon:9606	2.34693556	0.0010266	182324	1902	CD81 molecule	gene	biological_process-&-1&-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0046813-&&-receptor-mediated virion attachment to host cell-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0008104-&&-protein localization-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0043128-&&-positive regulation of 1-phosphatidylinositol 4-kinase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0061462-&&-protein localization to lysosome-%%-GO:0008283-&&-cell proliferation-%%-GO:0031623-&&-receptor internalization-%%-GO:0050776-&&-regulation of immune response-%%-GO:1904352-&&-positive regulation of protein catabolic process in the vacuole-%%-GO:2000145-&&-regulation of cell motility|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:1990459-&&-transferrin receptor binding	G:9606:CD81			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05144-&&-Malaria	CD81	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD81	0.42608754	0.10898166	199	4	FALSE	CD81	CD81	139.4923858	0	198	0	0.77551074	FALSE	1	CD81	2213230	0.0352215
793038	taxon:9606	2.1939499	0.00157848	180855	1902	nuclear receptor subfamily 3 group C member 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043402-&&-glucocorticoid mediated signaling pathway-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0038051-&&-glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005496-&&-steroid binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004883-&&-glucocorticoid receptor activity-%%-GO:1990239-&&-steroid hormone binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NR3C1	NR3C1	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	NR3C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR3C1	0.45579892	0.0688905	199	4	FALSE	NR3C1	NR3C1	119.0913706	0	198	0	0.80100835	FALSE	1	NR3C1	2169948	0.02419057
792551	taxon:9606	2.17976997	0.005294	181821	1902	caveolin 1	gene	biological_process-&-1&-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0007595-&&-lactation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0070836-&&-caveola assembly-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0008104-&&-protein localization-%%-GO:0086098-&&-angiotensin-activated signaling pathway involved in heart process-%%-GO:0044860-&&-protein localization to plasma membrane raft-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:2000535-&&-regulation of entry of bacterium into host cell-%%-GO:0032507-&&-maintenance of protein location in cell-%%-GO:1900085-&&-negative regulation of peptidyl-tyrosine autophosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060056-&&-mammary gland involution-%%-GO:0002931-&&-response to ischemia-%%-GO:0060355-&&-positive regulation of cell adhesion molecule production-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006816-&&-calcium ion transport-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0043627-&&-response to estrogen-%%-GO:0001525-&&-angiogenesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0098903-&&-regulation of membrane repolarization during action potential-%%-GO:0031623-&&-receptor internalization-%%-GO:0009617-&&-response to bacterium-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1901979-&&-regulation of inward rectifier potassium channel activity-%%-GO:0019217-&&-regulation of fatty acid metabolic process-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0051899-&&-membrane depolarization-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:1903361-&&-protein localization to basolateral plasma membrane-%%-GO:0051592-&&-response to calcium ion-%%-GO:0030301-&&-cholesterol transport-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000165-&&-MAPK cascade-%%-GO:0016050-&&-vesicle organization-%%-GO:0042524-&&-negative regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:2000286-&&-receptor internalization involved in canonical Wnt signaling pathway-%%-GO:0019065-&&-receptor-mediated endocytosis of virus by host cell-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0031295-&&-T cell costimulation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0030879-&&-mammary gland development-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:1903598-&&-positive regulation of gap junction assembly-%%-GO:0019915-&&-lipid storage-%%-GO:0042310-&&-vasoconstriction-%%-GO:1901844-&&-regulation of cell communication by electrical coupling involved in cardiac conduction-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:0048550-&&-negative regulation of pinocytosis-%%-GO:0052547-&&-regulation of peptidase activity-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0032570-&&-response to progesterone-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0033484-&&-nitric oxide homeostasis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0003057-&&-regulation of the force of heart contraction by chemical signal-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006874-&&-cellular calcium ion homeostasis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005929-&&-cilium-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005768-&&-endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005622-&&-intracellular-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0044325-&&-ion channel binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0015485-&&-cholesterol binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070320-&&-inward rectifier potassium channel inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005113-&&-patched binding-%%-GO:0050998-&&-nitric-oxide synthase binding	G:9606:CAV1	CAV1	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells	CAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAV1	0.458764	0.04992151	198	4	FALSE	CAV1	CAV1	107.2806122	0	197	0	0.80337167	FALSE	1	CAV1	4976358	0.02144838
787152	taxon:9606	2.18481172	0.00121613	179978	1902	lamin A/C	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0035105-&&-sterol regulatory element binding protein import into nucleus-%%-GO:0030951-&&-establishment or maintenance of microtubule cytoskeleton polarity-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0090343-&&-positive regulation of cell aging-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0072201-&&-negative regulation of mesenchymal cell proliferation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005638-&&-lamin filament-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:LMNA	LMNA	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04210-&&-Apoptosis-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	LMNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMNA	0.45770534	0.09288924	197	4	FALSE	LMNA	LMNA	169.6358974	0	196	0	0.80253138	FALSE	1	LMNA	2191424	0.03403198
788263	taxon:9606	2.18402395	4.90E-04	177973	1902	ribosomal protein S3A	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0030154-&&-cell differentiation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS3A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS3A	0.45787044	0.32360021	196	4	FALSE	RPS3A	RPS3A	213.9591837	0	196	0	0.80266268	FALSE	0	RPS3A	1230700	0.04287452
789082	taxon:9606	2.28076256	9.80E-04	176227	1902	lysine acetyltransferase 2B	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0043970-&&-histone H3-K9 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0048511-&&-rhythmic process-%%-GO:0006473-&&-protein acetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0018076-&&-N-terminal peptidyl-lysine acetylation-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010835-&&-regulation of protein ADP-ribosylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0016032-&&-viral process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0018394-&&-peptidyl-lysine acetylation|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0031674-&&-I band-%%-GO:0000125-&&-PCAF complex-%%-GO:0042641-&&-actomyosin-%%-GO:0005634-&&-nucleus-%%-GO:0000776-&&-kinetochore-%%-GO:0031672-&&-A band-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004468-&&-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity	G:9606:KAT2B			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	KAT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT2B	0.43844985	0.10603066	196	4	FALSE	KAT2B	KAT2B	136.4536083	0	195	0	0.78653957	FALSE	1	KAT2B	1731234	0.03106867
787022	taxon:9606	2.25224516	0.00115262	180219	1902	eukaryotic translation initiation factor 6	gene	biological_process-&-1&-GO:0032868-&&-response to insulin-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:1902626-&&-assembly of large subunit precursor of preribosome-%%-GO:0006413-&&-translational initiation-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0000054-&&-ribosomal subunit export from nucleus-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0035195-&&-gene silencing by miRNA-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0045652-&&-regulation of megakaryocyte differentiation-%%-GO:0042256-&&-mature ribosome assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0043022-&&-ribosome binding	G:9606:EIF6	EIF6	TRUE	KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	EIF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF6	0.4440014	0.08146973	195	4	FALSE	EIF6	EIF6	126.8615385	0	195	0	0.79129247	FALSE	0	EIF6	1630180	0.02784204
787797	taxon:9606	2.18685993	0.00288259	178769	1902	protein kinase cAMP-activated catalytic subunit alpha	gene	biological_process-&-1&-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0001707-&&-mesoderm formation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1901621-&&-negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0006397-&&-mRNA processing-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0070613-&&-regulation of protein processing-%%-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0034605-&&-cellular response to heat-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0007596-&&-blood coagulation-%%-GO:0048240-&&-sperm capacitation-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0001843-&&-neural tube closure-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0043197-&&-dendritic spine-%%-GO:0034704-&&-calcium channel complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0097546-&&-ciliary base-%%-GO:0036126-&&-sperm flagellum-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PRKACA			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04530-&&-Tight junction-%%-hsa04740-&&-Olfactory transduction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05030-&&-Cocaine addiction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04970-&&-Salivary secretion	PRKACA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKACA	0.45727666	0.03690193	195	4	FALSE	PRKACA	PRKACA	99.28205128	0	195	0	0.80219001	FALSE	0	PRKACA	2965630	0.02004332
787453	taxon:9606	2.17724909	9.63E-04	179406	1902	mitogen-activated protein kinase kinase kinase 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05161-&&-Hepatitis B	MAP3K1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K1	0.45929517	0.0973822	193	4	FALSE	MAP3K1	MAP3K1	159.7905759	0	192	0	0.80379182	FALSE	1	MAP3K1	1716412	0.03171395
787536	taxon:9606	2.17283756	0.0016954	179231	1902	protein phosphatase 1 catalytic subunit gamma	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0051301-&&-cell division-%%-GO:0030182-&&-neuron differentiation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0043197-&&-dendritic spine-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005521-&&-lamin binding	G:9606:PPP1CC			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa04218-&&-Cellular senescence-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1CC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CC	0.46022768	0.07507556	193	4	FALSE	PPP1CC	PPP1CC	136.2435233	0	193	0	0.80452707	FALSE	0	PPP1CC	2397780	0.02689595
792244	taxon:9606	2.41941075	7.80E-04	165973	1902	immunoglobulin superfamily member 8	gene	biological_process-&-1&-GO:0007338-&&-single fertilization-%%-GO:0007399-&&-nervous system development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:IGSF8				IGSF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGSF8	0.41332378	0.12273316	193	4	FALSE	IGSF8	IGSF8	133.1502591	0	193	0	0.76343154	FALSE	0	IGSF8	1845628	0.03785315
792863	taxon:9606	2.22514574	9.77E-04	181255	1902	fibrillarin	gene	biological_process-&-1&-GO:0031167-&&-rRNA methylation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0048254-&&-snoRNA localization-%%-GO:1990258-&&-histone glutamine methylation-%%-GO:0006364-&&-rRNA processing-%%-GO:0008033-&&-tRNA processing-%%-GO:0000494-&&-box C/D snoRNA 3'-end processing|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0001651-&&-dense fibrillar component-%%-GO:0005694-&&-chromosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0001652-&&-granular component-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008649-&&-rRNA methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:1990259-&&-histone-glutamine methyltransferase activity	G:9606:FBL			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	FBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBL	0.44940877	0.15414508	193	4	FALSE	FBL	FBL	173.5129534	0	193	0	0.79580904	FALSE	0	FBL	1654908	0.03662601
793306	taxon:9606	2.19552545	0.00190855	180337	1902	huntingtin	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006915-&&-apoptotic process-%%-GO:0031587-&&-positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:1905337-&&-positive regulation of aggrephagy-%%-GO:0048513-&&-animal organ development-%%-GO:0007030-&&-Golgi organization-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:1904504-&&-positive regulation of lipophagy-%%-GO:0042297-&&-vocal learning-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0030425-&&-dendrite-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005814-&&-centriole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005522-&&-profilin binding-%%-GO:0002039-&&-p53 binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0008134-&&-transcription factor binding	G:9606:HTT			KEGG-&-1&-hsa05016-&&-Huntington disease	HTT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTT	0.45547183	0.05146199	192	4	FALSE	HTT	HTT	124.3842105	0	191	0	0.80074576	FALSE	1	HTT	2421826	0.02531374
788814	taxon:9606	2.25838979	0.00145018	176817	1902	ubiquitin conjugating enzyme E2 D1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2D1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D1	0.44279336	0.05274119	191	4	FALSE	UBE2D1	UBE2D1	109.7830688	0	190	0	0.79026837	FALSE	1	UBE2D1	2100480	0.02419912
790955	taxon:9606	2.28391366	7.50E-04	170619	1902	WW domain containing oxidoreductase	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0050662-&&-coenzyme binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0048037-&&-cofactor binding	G:9606:WWOX				WWOX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWOX	0.43784492	0.06359879	191	4	FALSE	WWOX	WWOX	116.1308901	0	191	0	0.78601439	FALSE	0	WWOX	1212832	0.02654429
787201	taxon:9606	2.38222782	2.97E-04	179882	1902	mago homolog, exon junction complex core component	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006417-&&-regulation of translation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:MAGOH			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	MAGOH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGOH	0.41977513	0.11616794	190	4	FALSE	MAGOH	MAGOH	143.4148936	0	189	0	0.7696287	FALSE	1	MAGOH	812090	0.03804977
788264	taxon:9606	2.19788877	2.91E-04	177972	1902	ribosomal protein S4, X-linked	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS4X			KEGG-&-1&-hsa03010-&&-Ribosome	RPS4X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS4X	0.45498208	0.35371763	190	4	FALSE	RPS4X	RPS4X	210.0842105	0	190	0	0.80035187	FALSE	0	RPS4X	924826	0.04278701
792998	taxon:9606	2.24578541	0.00248363	181017	1902	Fos proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0034097-&&-response to cytokine-%%-GO:0051412-&&-response to corticosterone-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001661-&&-conditioned taste aversion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030431-&&-sleep-%%-GO:0006306-&&-DNA methylation-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007565-&&-female pregnancy-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0009629-&&-response to gravity-%%-GO:0006954-&&-inflammatory response-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007399-&&-nervous system development-%%-GO:0009416-&&-response to light stimulus-%%-GO:0009636-&&-response to toxic substance-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:FOS	FOS	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05140-&&-Leishmaniasis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04713-&&-Circadian entrainment-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	FOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOS	0.44527852	0.04738878	190	4	FALSE	FOS	FOS	95.40957447	0	189	0	0.7923691	FALSE	1	FOS	2840636	0.02076218
787310	taxon:9606	2.16369939	0.00123244	179683	1902	karyopherin subunit beta 1	gene	biological_process-&-1&-GO:0040001-&&-establishment of mitotic spindle localization-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007079-&&-mitotic chromosome movement towards spindle pole-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0031291-&&-Ran protein signal transduction-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006610-&&-ribosomal protein import into nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0034399-&&-nuclear periphery-%%-GO:0071782-&&-endoplasmic reticulum tubular network-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNB1			KEGG-&-1&-hsa03013-&&-RNA transport	KPNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNB1	0.46217141	0.085504	189	4	FALSE	KPNB1	KPNB1	172.3903743	0	188	0	0.8060501	FALSE	1	KPNB1	2165840	0.03362402
788779	taxon:9606	2.13234599	0.00217879	176918	1902	tubulin alpha 1a	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0051301-&&-cell division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0055037-&&-recycling endosome-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0019904-&&-protein domain specific binding	G:9606:TUBA1A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1A	0.46896705	0.08262974	189	4	FALSE	TUBA1A	TUBA1A	159.0793651	0	189	0	0.81127567	FALSE	0	TUBA1A	3006056	0.0298823
788267	taxon:9606	2.22010399	3.05E-04	177969	1902	ribosomal protein S6	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048821-&&-erythrocyte development-%%-GO:0002309-&&-T cell proliferation involved in immune response-%%-GO:0006413-&&-translational initiation-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0022605-&&-oogenesis stage-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001890-&&-placenta development-%%-GO:0007369-&&-gastrulation-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006412-&&-translation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0019083-&&-viral transcription-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0031929-&&-TOR signaling|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005844-&&-polysome-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS6			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa03010-&&-Ribosome-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04066-&&-HIF-1 signaling pathway	RPS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6	0.45042935	0.35242917	188	4	FALSE	RPS6	RPS6	199.7393617	0	188	0	0.79664934	FALSE	0	RPS6	850838	0.04183899
788626	taxon:9606	2.3349614	0.00100365	177290	1902	telomeric repeat binding factor 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0032205-&&-negative regulation of telomere maintenance-%%-GO:0090398-&&-cellular senescence-%%-GO:0000723-&&-telomere maintenance-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:1905778-&&-negative regulation of exonuclease activity-%%-GO:1904430-&&-negative regulation of t-circle formation-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032214-&&-negative regulation of telomere maintenance via semi-conservative replication-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0032210-&&-regulation of telomere maintenance via telomerase-%%-GO:1905839-&&-negative regulation of telomeric D-loop disassembly-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0007049-&&-cell cycle-%%-GO:0016233-&&-telomere capping-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:1903824-&&-negative regulation of telomere single strand break repair-%%-GO:0031627-&&-telomeric loop formation-%%-GO:0032208-&&-negative regulation of telomere maintenance via recombination-%%-GO:1903770-&&-negative regulation of beta-galactosidase activity-%%-GO:0032204-&&-regulation of telomere maintenance|cellular_component-&-1&-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070187-&&-shelterin complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0030870-&&-Mre11 complex-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0044877-&&-macromolecular complex binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003720-&&-telomerase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding	G:9606:TERF2				TERF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF2	0.4282726	0.04722024	186	4	FALSE	TERF2	TERF2	100.125	0	185	0	0.77750643	FALSE	1	TERF2	1402182	0.02470746
788387	taxon:9606	2.17472822	0.00205628	177753	1902	signal transducer and activator of transcription 1	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0046725-&&-negative regulation by virus of viral protein levels in host cell-%%-GO:0072136-&&-metanephric mesenchymal cell proliferation involved in metanephros development-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0008015-&&-blood circulation-%%-GO:0072308-&&-negative regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0051591-&&-response to cAMP-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061326-&&-renal tubule development-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0051607-&&-defense response to virus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0003340-&&-negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0072162-&&-metanephric mesenchymal cell differentiation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0016525-&&-negative regulation of angiogenesis|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0030425-&&-dendrite-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0019899-&&-enzyme binding	G:9606:STAT1	STAT1	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	STAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT1	0.45982757	0.06323185	185	4	FALSE	STAT1	STAT1	125.2786885	0	184	0	0.80421196	FALSE	1	STAT1	2698486	0.02476518
788082	taxon:9606	2.19694344	2.94E-04	178268	1902	ribosomal protein lateral stalk subunit P0	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPLP0			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP0	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP0	0.45517785	0.33891661	184	4	FALSE	RPLP0	RPLP0	217.9619565	0	184	0	0.80050943	FALSE	0	RPLP0	861332	0.04428321
788692	taxon:9606	2.26091067	0.00129907	177168	1902	TNF receptor superfamily member 1A	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0006693-&&-prostaglandin metabolic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0006954-&&-inflammatory response-%%-GO:0006955-&&-immune response-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0016032-&&-viral process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043120-&&-tumor necrosis factor binding	G:9606:TNFRSF1A			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	TNFRSF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF1A	0.44229965	0.07856232	184	4	FALSE	TNFRSF1A	TNFRSF1A	124.2417582	0	183	0	0.78984822	FALSE	1	TNFRSF1A	1903146	0.02751146
789092	taxon:9606	2.1476288	0.00165961	176205	1902	sequestosome 1	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000422-&&-mitophagy-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006914-&&-autophagy-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006950-&&-response to stress-%%-GO:0008104-&&-protein localization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0061635-&&-regulation of protein complex stability-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0016197-&&-endosomal transport-%%-GO:0002376-&&-immune system process|cellular_component-&-1&-GO:0044753-&&-amphisome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0097225-&&-sperm midpiece-%%-GO:0016605-&&-PML body-%%-GO:0005770-&&-late endosome-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016234-&&-inclusion body-%%-GO:0044754-&&-autolysosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SQSTM1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04217-&&-Necroptosis	SQSTM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SQSTM1	0.46562981	0.07516241	184	4	FALSE	SQSTM1	SQSTM1	145.6703297	0	183	0	0.80872853	FALSE	1	SQSTM1	2310518	0.02784114
788053	taxon:9606	2.20308807	4.50E-04	178301	1902	ribosomal protein L13	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL13			KEGG-&-1&-hsa03010-&&-Ribosome	RPL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL13	0.45390832	0.29724374	183	4	FALSE	RPL13	RPL13	200.1530055	0	183	0	0.79948532	FALSE	0	RPL13	1152760	0.04099816
789236	taxon:9606	2.17157712	8.67E-04	175935	1902	RuvB like AAA ATPase 1	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0051301-&&-cell division-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006310-&&-DNA recombination-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion|cellular_component-&-1&-GO:0097255-&&-R2TP complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0031011-&&-Ino80 complex-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043141-&&-ATP-dependent 5'-3' DNA helicase activity-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding	G:9606:RUVBL1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	RUVBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUVBL1	0.46049481	0.10564764	183	4	FALSE	RUVBL1	RUVBL1	177.0662983	0	182	0	0.80473715	FALSE	1	RUVBL1	1780220	0.03482597
789419	taxon:9606	2.19836143	9.75E-04	175527	1902	ribosomal protein L23	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070180-&&-large ribosomal subunit rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL23			KEGG-&-1&-hsa03010-&&-Ribosome	RPL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL23	0.45488425	0.3042695	183	4	FALSE	RPL23	RPL23	184.6338798	0	183	0	0.80027309	FALSE	0	RPL23	1616030	0.03757734
791062	taxon:9606	2.21915866	9.77E-04	170191	1902	OTU deubiquitinase, ubiquitin aldehyde binding 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:2000780-&&-negative regulation of double-strand break repair-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1901315-&&-negative regulation of histone H2A K63-linked ubiquitination-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019784-&&-NEDD8-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:OTUB1				OTUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUB1	0.45062123	0.06249233	181	4	FALSE	OTUB1	OTUB1	129.8895028	0	181	0	0.79680689	FALSE	0	OTUB1	1610006	0.02713832
791277	taxon:9606	2.39183866	0.00133877	169406	1902	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0072686-&&-mitotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HECW2				HECW2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HECW2	0.4180884	0.01569267	181	4	FALSE	HECW2	HECW2	65	0	180	0	0.76802689	FALSE	1	HECW2	1367756	0.01770003
793308	taxon:9606	2.3133764	3.32E-04	180333	1902	hepatoma derived growth factor	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0008283-&&-cell proliferation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0008201-&&-heparin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001222-&&-transcription corepressor binding	G:9606:HDGF				HDGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDGF	0.43226861	0.11006753	181	4	FALSE	HDGF	HDGF	152.8839779	0	181	0	0.78110393	FALSE	0	HDGF	888148	0.03637365
788225	taxon:9606	2.28927052	0.00143944	178049	1902	tripartite motif containing 27	gene	biological_process-&-1&-GO:0070206-&&-protein trimerization-%%-GO:0002820-&&-negative regulation of adaptive immune response-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0090281-&&-negative regulation of calcium ion import-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1900041-&&-negative regulation of interleukin-2 secretion-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0072643-&&-interferon-gamma secretion-%%-GO:0008283-&&-cell proliferation-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045087-&&-innate immune response-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0051127-&&-positive regulation of actin nucleation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity	G:9606:TRIM27				TRIM27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM27	0.43682037	0.03954802	180	4	FALSE	TRIM27	TRIM27	96.70786517	0	179	0	0.78512158	FALSE	1	TRIM27	1873998	0.02229177
792543	taxon:9606	2.23333859	0.00265946	181829	1902	caspase 8	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0036462-&&-TRAIL-activated apoptotic signaling pathway-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0060715-&&-syncytiotrophoblast cell differentiation involved in labyrinthine layer development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0039650-&&-suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0042110-&&-T cell activation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0046677-&&-response to antibiotic-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0006508-&&-proteolysis-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0042113-&&-B cell activation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0009409-&&-response to cold|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0097342-&&-ripoptosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0097199-&&-cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP8	CASP8	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance	CASP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP8	0.44776014	0.05585516	179	4	FALSE	CASP8	CASP8	96.0960452	0	178	0	0.79444357	FALSE	1	CASP8	2663382	0.02052235
788172	taxon:9606	2.19489523	0.0020064	178131	1902	Raf-1 proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007507-&&-heart development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030878-&&-thyroid gland development-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0035773-&&-insulin secretion involved in cellular response to glucose stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0060324-&&-face development-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0048538-&&-thymus development-%%-GO:0030168-&&-platelet activation-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008283-&&-cell proliferation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0042060-&&-wound healing-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016607-&&-nuclear speck-%%-GO:0031143-&&-pseudopodium|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0019899-&&-enzyme binding	G:9606:RAF1	RAF1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	RAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAF1	0.45560261	0.06837662	178	4	FALSE	RAF1	RAF1	123.7840909	0	177	0	0.8008508	FALSE	1	RAF1	2342998	0.02507369
788484	taxon:9606	2.26894596	0.0010867	177567	1902	small ubiquitin-like modifier 2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016925-&&-protein sumoylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019789-&&-SUMO transferase activity	G:9606:SUMO2			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO2	0.44073328	0.06493506	178	4	FALSE	SUMO2	SUMO2	123.3579546	0	177	0	0.78850901	FALSE	1	SUMO2	1528986	0.02758179
788489	taxon:9606	2.19300457	0.00168405	177558	1902	synuclein alpha	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0006915-&&-apoptotic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0051585-&&-negative regulation of dopamine uptake involved in synaptic transmission-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0001774-&&-microglial cell activation-%%-GO:0010040-&&-response to iron(II) ion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0010517-&&-regulation of phospholipase activity-%%-GO:0070495-&&-negative regulation of thrombin-activated receptor signaling pathway-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0007006-&&-mitochondrial membrane organization-%%-GO:0045920-&&-negative regulation of exocytosis-%%-GO:0050812-&&-regulation of acyl-CoA biosynthetic process-%%-GO:0006638-&&-neutral lipid metabolic process-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:1903421-&&-regulation of synaptic vesicle recycling-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:1905606-&&-regulation of presynapse assembly-%%-GO:0014048-&&-regulation of glutamate secretion-%%-GO:0050808-&&-synapse organization-%%-GO:0031623-&&-receptor internalization-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0060732-&&-positive regulation of inositol phosphate biosynthetic process-%%-GO:0032769-&&-negative regulation of monooxygenase activity-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0031648-&&-protein destabilization-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051622-&&-negative regulation of norepinephrine uptake-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:1902957-&&-negative regulation of mitochondrial electron transport, NADH to ubiquinone-%%-GO:1904715-&&-negative regulation of chaperone-mediated autophagy-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0040012-&&-regulation of locomotion-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0051612-&&-negative regulation of serotonin uptake-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:1903284-&&-positive regulation of glutathione peroxidase activity-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:1903426-&&-regulation of reactive oxygen species biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0043030-&&-regulation of macrophage activation-%%-GO:0001956-&&-positive regulation of neurotransmitter secretion-%%-GO:1903285-&&-positive regulation of hydrogen peroxide catabolic process-%%-GO:0007568-&&-aging-%%-GO:0042775-&&-mitochondrial ATP synthesis coupled electron transport-%%-GO:0045963-&&-negative regulation of dopamine metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0035067-&&-negative regulation of histone acetylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005840-&&-ribosome-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0098794-&&-postsynapse-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005938-&&-cell cortex-%%-GO:0030054-&&-cell junction-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005764-&&-lysosome-%%-GO:0099512-&&-supramolecular fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0016234-&&-inclusion body-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043195-&&-terminal bouton-%%-GO:0005615-&&-extracellular space-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0060961-&&-phospholipase D inhibitor activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0070840-&&-dynein complex binding	G:9606:SNCA			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease	SNCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNCA	0.4559954	0.05720779	178	4	FALSE	SNCA	SNCA	119.5795455	0	177	0	0.80116591	FALSE	1	SNCA	2052710	0.0241506
787702	taxon:9606	2.17630377	0.00155187	178916	1902	polo like kinase 1	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0051297-&&-centrosome organization-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0031648-&&-protein destabilization-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0016321-&&-female meiosis chromosome segregation-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000910-&&-cytokinesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0090435-&&-protein localization to nuclear envelope-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045143-&&-homologous chromosome segregation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0070194-&&-synaptonemal complex disassembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0051233-&&-spindle midzone|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0010997-&&-anaphase-promoting complex binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding	G:9606:PLK1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	PLK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLK1	0.45949468	0.06640394	177	4	FALSE	PLK1	PLK1	139.4228571	0	176	0	0.80394937	FALSE	1	PLK1	2092910	0.02758531
788197	taxon:9606	2.25413581	7.87E-04	178099	1902	RB binding protein 4, chromatin remodeling factor	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0016575-&&-histone deacetylation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0031497-&&-chromatin assembly-%%-GO:0060416-&&-response to growth hormone-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0016581-&&-NuRD complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016580-&&-Sin3 complex-%%-GO:0016589-&&-NURF complex-%%-GO:0033186-&&-CAF-1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0042393-&&-histone binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:RBBP4			KEGG-&-1&-hsa04218-&&-Cellular senescence	RBBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP4	0.44362899	0.1680791	177	4	FALSE	RBBP4	RBBP4	183.4350283	0	177	0	0.79097736	FALSE	0	RBBP4	1640066	0.04010645
790853	taxon:9606	2.2569718	6.41E-04	170894	1902	defective in cullin neddylation 1 domain containing 1	gene	biological_process-&-1&-GO:0045116-&&-protein neddylation-%%-GO:0008150-&&-biological_process-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0032182-&&-ubiquitin-like protein binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0005515-&&-protein binding	G:9606:DCUN1D1				DCUN1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCUN1D1	0.44307155	0.12910889	177	4	FALSE	DCUN1D1	DCUN1D1	145.1186441	0	177	0	0.7905047	FALSE	0	DCUN1D1	1180504	0.03183124
792421	taxon:9606	2.23412636	0.00152545	182048	1902	casein kinase 2 alpha 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006915-&&-apoptotic process-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0097421-&&-liver regeneration-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071174-&&-mitotic spindle checkpoint-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:CSNK2A2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A2	0.44760226	0.05354391	177	4	FALSE	CSNK2A2	CSNK2A2	120.8135593	0	177	0	0.79431227	FALSE	0	CSNK2A2	2005948	0.02575139
788043	taxon:9606	2.21521979	2.18E-04	178312	1902	ribosomal protein L4	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL4			KEGG-&-1&-hsa03010-&&-Ribosome	RPL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL4	0.45142248	0.3812987	176	4	FALSE	RPL4	RPL4	211.3522727	0	176	0	0.79746337	FALSE	0	RPL4	701786	0.04389219
788284	taxon:9606	2.22593351	2.01E-04	177955	1902	ribosomal protein S14	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0006412-&&-translation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0019083-&&-viral transcription|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0070181-&&-small ribosomal subunit rRNA binding	G:9606:RPS14			KEGG-&-1&-hsa03010-&&-Ribosome	RPS14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS14	0.44924972	0.36305195	176	4	FALSE	RPS14	RPS14	224.0170455	0	176	0	0.79567775	FALSE	0	RPS14	766766	0.04717141
788138	taxon:9606	2.26579486	0.00109815	178174	1902	paxillin	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007172-&&-signal complex assembly-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0006936-&&-muscle contraction-%%-GO:0060396-&&-growth hormone receptor signaling pathway|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005178-&&-integrin binding	G:9606:PXN			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection	PXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PXN	0.44134622	0.09436752	175	4	FALSE	PXN	PXN	130.1387283	0	174	0	0.78903419	FALSE	1	PXN	1567278	0.02897898
788272	taxon:9606	2.29510005	3.32E-04	177964	1902	ribosomal protein S6 kinase B2	gene	biological_process-&-1&-GO:0043491-&&-protein kinase B signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0006412-&&-translation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045948-&&-positive regulation of translational initiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042277-&&-peptide binding-%%-GO:0004711-&&-ribosomal protein S6 kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:RPS6KB2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RPS6KB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KB2	0.43571085	0.08124795	175	4	FALSE	RPS6KB2	RPS6KB2	141.8685714	0	175	0	0.78414999	FALSE	0	RPS6KB2	780518	0.03284358
788277	taxon:9606	2.27304238	2.45E-04	177962	1902	ribosomal protein S7	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0030154-&&-cell differentiation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001843-&&-neural tube closure-%%-GO:0042274-&&-ribosomal small subunit biogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS7			KEGG-&-1&-hsa03010-&&-Ribosome	RPS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS7	0.439939	0.32788177	175	4	FALSE	RPS7	RPS7	208.8857143	0	175	0	0.78782627	FALSE	0	RPS7	746360	0.04691696
788726	taxon:9606	2.18701749	8.78E-04	177105	1902	chaperonin containing TCP1 subunit 3	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0046931-&&-pore complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0044297-&&-cell body-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CCT3				CCT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT3	0.45724371	0.12716763	174	4	FALSE	CCT3	CCT3	180.0172414	0	174	0	0.80216375	FALSE	0	CCT3	1897340	0.03601065
790092	taxon:9606	2.28391366	0.00122228	173889	1902	Fas associated factor family member 2	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0034389-&&-lipid particle organization-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0035473-&&-lipase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0055102-&&-lipase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:FAF2				FAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAF2	0.43784492	0.05541956	174	4	FALSE	FAF2	FAF2	105.7093023	0	173	0	0.78601439	FALSE	1	FAF2	1558578	0.02412373
788046	taxon:9606	2.23113282	3.21E-04	178308	1902	ribosomal protein L7	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005844-&&-polysome-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding	G:9606:RPL7			KEGG-&-1&-hsa03010-&&-Ribosome	RPL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL7	0.44820281	0.39456484	173	4	FALSE	RPL7	RPL7	216.619883	0	172	0	0.7948112	FALSE	1	RPL7	715580	0.04590129
788065	taxon:9606	2.28958563	1.70E-04	178289	1902	ribosomal protein L24	gene	biological_process-&-1&-GO:0021554-&&-optic nerve development-%%-GO:0006412-&&-translation-%%-GO:1902626-&&-assembly of large subunit precursor of preribosome-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0006413-&&-translational initiation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0010458-&&-exit from mitosis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL24			KEGG-&-1&-hsa03010-&&-Ribosome	RPL24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL24	0.43676025	0.37276516	173	4	FALSE	RPL24	RPL24	213.7572254	0	173	0	0.78506906	FALSE	0	RPL24	680898	0.04908185
788283	taxon:9606	2.20151253	2.66E-04	177952	1902	ribosomal protein S16	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0042274-&&-ribosomal small subunit biogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS16			KEGG-&-1&-hsa03010-&&-Ribosome	RPS16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS16	0.45423316	0.38412421	173	4	FALSE	RPS16	RPS16	209.2485549	0	173	0	0.79974791	FALSE	0	RPS16	862492	0.04262549
792542	taxon:9606	2.21490468	0.00164823	181834	1902	caspase 3	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0030182-&&-neuron differentiation-%%-GO:0007507-&&-heart development-%%-GO:0007611-&&-learning or memory-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030220-&&-platelet formation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0009749-&&-response to glucose-%%-GO:0042060-&&-wound healing-%%-GO:0043200-&&-response to amino acid-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0042493-&&-response to drug-%%-GO:0006915-&&-apoptotic process-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0035329-&&-hippo signaling-%%-GO:0006508-&&-proteolysis-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0001666-&&-response to hypoxia-%%-GO:0032355-&&-response to estradiol-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0009411-&&-response to UV-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016485-&&-protein processing-%%-GO:0045165-&&-cell fate commitment-%%-GO:0010165-&&-response to X-ray-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0035094-&&-response to nicotine-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0021766-&&-hippocampus development-%%-GO:0030889-&&-negative regulation of B cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0045121-&&-membrane raft-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004190-&&-aspartic-type endopeptidase activity-%%-GO:0005123-&&-death receptor binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0016005-&&-phospholipase A2 activator activity-%%-GO:0002020-&&-protease binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP3	CASP3	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05146-&&-Amoebiasis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa01524-&&-Platinum drug resistance	CASP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP3	0.4514867	0.05448916	173	4	FALSE	CASP3	CASP3	109.0877193	0	172	0	0.79751589	FALSE	1	CASP3	2012616	0.02262276
787533	taxon:9606	2.26941862	8.39E-04	179232	1902	protein phosphatase 1 catalytic subunit beta	gene	biological_process-&-1&-GO:0005981-&&-regulation of glycogen catabolic process-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0051301-&&-cell division-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0042587-&&-glycogen granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0000164-&&-protein phosphatase type 1 complex|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0017018-&&-myosin phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0050115-&&-myosin-light-chain-phosphatase activity	G:9606:PPP1CB	PPP1CB	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05034-&&-Alcoholism-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04218-&&-Cellular senescence-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1CB	0.44064149	0.09506324	172	4	FALSE	PPP1CB	PPP1CB	118.5813954	0	172	0	0.78843023	FALSE	0	PPP1CB	1333674	0.02646186
787645	taxon:9606	2.16763825	5.43E-04	179020	1902	Y-box binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0051154-&&-negative regulation of striated muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0070937-&&-CRD-mediated mRNA stability complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:YBX1				YBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBX1	0.46133159	0.15273234	172	4	FALSE	YBX1	YBX1	207.5941177	0	171	0	0.80539362	FALSE	1	YBX1	1291862	0.04049037
788330	taxon:9606	2.36568458	0.00184713	177872	1902	ataxin 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051168-&&-nuclear export-%%-GO:0006396-&&-RNA processing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0042272-&&-nuclear RNA export factor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0034046-&&-poly(G) binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008266-&&-poly(U) RNA binding	G:9606:ATXN1				ATXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN1	0.42271062	0.03508528	172	4	FALSE	ATXN1	ATXN1	92.52352941	0	171	0	0.7723859	FALSE	1	ATXN1	2275296	0.0239302
788815	taxon:9606	2.31384906	9.93E-04	176816	1902	ubiquitin conjugating enzyme E2 D2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2D2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05131-&&-Shigellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D2	0.43218031	0.06418378	172	4	FALSE	UBE2D2	UBE2D2	100.9941177	0	171	0	0.78102516	FALSE	1	UBE2D2	1464462	0.02404062
790332	taxon:9606	2.28139278	9.69E-04	173297	1902	SIN3 transcription regulator family member A	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0010817-&&-regulation of hormone levels-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031937-&&-positive regulation of chromatin silencing-%%-GO:0034613-&&-cellular protein localization-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0051595-&&-response to methylglyoxal-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0048511-&&-rhythmic process-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0007568-&&-aging-%%-GO:1901675-&&-negative regulation of histone H3-K27 acetylation-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016575-&&-histone deacetylation-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006476-&&-protein deacetylation-%%-GO:0006260-&&-DNA replication-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:SIN3A			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05016-&&-Huntington disease	SIN3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIN3A	0.43832873	0.09302326	172	4	FALSE	SIN3A	SIN3A	118.0232558	0	172	0	0.78643454	FALSE	0	SIN3A	1461306	0.0267917
790618	taxon:9606	2.26910351	0.00107158	171740	1902	ubiquitin C-terminal hydrolase L5	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:0048853-&&-forebrain morphogenesis-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0030901-&&-midbrain development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0031011-&&-Ino80 complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0003723-&&-RNA binding	G:9606:UCHL5				UCHL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UCHL5	0.44070268	0.0994779	172	4	FALSE	UCHL5	UCHL5	123.1176471	0	171	0	0.78848275	FALSE	1	UCHL5	1536746	0.02753478
792294	taxon:9606	2.25098472	0.00105749	182279	1902	cyclin dependent kinase 9	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0031297-&&-replication fork processing-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031056-&&-regulation of histone modification-%%-GO:0051147-&&-regulation of muscle cell differentiation-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0008283-&&-cell proliferation-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006281-&&-DNA repair-%%-GO:1903839-&&-positive regulation of mRNA 3'-UTR binding-%%-GO:0042493-&&-response to drug-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0071345-&&-cellular response to cytokine stimulus|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0000932-&&-P-body-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005694-&&-chromosome-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0019901-&&-protein kinase binding	G:9606:CDK9			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	CDK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK9	0.44425002	0.07455621	172	4	FALSE	CDK9	CDK9	128.9411765	0	171	0	0.79150255	FALSE	1	CDK9	1529572	0.02805735
789795	taxon:9606	2.21364424	4.49E-04	174648	1902	heterogeneous nuclear ribonucleoprotein R	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0061157-&&-mRNA destabilization-%%-GO:0010467-&&-gene expression-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0007623-&&-circadian rhythm|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0043679-&&-axon terminus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:HNRNPR				HNRNPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPR	0.45174377	0.2006192	171	4	FALSE	HNRNPR	HNRNPR	203.6959064	0	171	0	0.79772596	FALSE	0	HNRNPR	1044794	0.04216313
793321	taxon:9606	2.19631322	0.00288476	180317	1902	hypoxia inducible factor 1 alpha subunit	gene	biological_process-&-1&-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0007165-&&-signal transduction-%%-GO:0014850-&&-response to muscle activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0007595-&&-lactation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0006089-&&-lactate metabolic process-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1903715-&&-regulation of aerobic respiration-%%-GO:0032364-&&-oxygen homeostasis-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001525-&&-angiogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0008542-&&-visual learning-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0051541-&&-elastin metabolic process-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032963-&&-collagen metabolic process-%%-GO:2001054-&&-negative regulation of mesenchymal cell apoptotic process-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0051216-&&-cartilage development-%%-GO:0070101-&&-positive regulation of chemokine-mediated signaling pathway-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0097411-&&-hypoxia-inducible factor-1alpha signaling pathway-%%-GO:0042541-&&-hemoglobin biosynthetic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0010573-&&-vascular endothelial growth factor production-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0021502-&&-neural fold elevation formation-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0001947-&&-heart looping-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0031514-&&-motile cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0019899-&&-enzyme binding	G:9606:HIF1A	HIF1A	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	HIF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIF1A	0.45530846	0.08235294	171	4	FALSE	HIF1A	HIF1A	139.251462	0	171	0	0.80061446	FALSE	0	HIF1A	3172660	0.02825225
787346	taxon:9606	2.22813928	5.71E-04	179619	1902	ribosomal protein SA	gene	biological_process-&-1&-GO:0000461-&&-endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0007155-&&-cell adhesion-%%-GO:0000447-&&-endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0006407-&&-rRNA export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030686-&&-90S preribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005055-&&-laminin receptor activity-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPSA			KEGG-&-1&-hsa03010-&&-Ribosome	RPSA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPSA	0.44880498	0.32050122	170	4	FALSE	RPSA	RPSA	197.1764706	0	170	0	0.79531012	FALSE	0	RPSA	983708	0.04157715
787698	taxon:9606	2.29809359	0.0014401	178927	1902	phospholipase C gamma 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0016477-&&-cell migration-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0007411-&&-axon guidance-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0016032-&&-viral process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0045766-&&-positive regulation of angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0035254-&&-glutamate receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0004629-&&-phospholipase C activity-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor	G:9606:PLCG1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05225-&&-Hepatocellular carcinoma	PLCG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCG1	0.43514329	0.08485903	170	4	FALSE	PLCG1	PLCG1	95.37647059	0	170	0	0.78365107	FALSE	0	PLCG1	1749436	0.02225136
788063	taxon:9606	2.27839924	2.08E-04	178292	1902	ribosomal protein L23a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0008283-&&-cell proliferation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031932-&&-TORC2 complex|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL23A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL23A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL23A	0.43890464	0.37932475	170	4	FALSE	RPL23A	RPL23A	199.3823529	0	170	0	0.78693346	FALSE	0	RPL23A	626584	0.04499715
787409	taxon:9606	2.40050418	0.00112234	179476	1902	NCK adaptor protein 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1903679-&&-positive regulation of cap-independent translational initiation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0051707-&&-response to other organism-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0036493-&&-positive regulation of translation in response to endoplasmic reticulum stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007172-&&-signal complex assembly-%%-GO:0042110-&&-T cell activation-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0007015-&&-actin filament organization-%%-GO:1903676-&&-positive regulation of cap-dependent translational initiation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane-%%-GO:0005840-&&-ribosome-%%-GO:0005634-&&-nucleus-%%-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0071074-&&-eukaryotic initiation factor eIF2 binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity	G:9606:NCK1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCK1	0.41657915	0.06008735	169	4	FALSE	NCK1	NCK1	69.52662722	0	169	0	0.76658264	FALSE	0	NCK1	1287570	0.01902106
788951	taxon:9606	2.31117063	8.81E-04	176546	1902	OFD1, centriole and centriolar satellite protein	gene	biological_process-&-1&-GO:0007067-&&-mitotic nuclear division-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0060287-&&-epithelial cilium movement involved in determination of left/right asymmetry-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0034451-&&-centriolar satellite-%%-GO:0016020-&&-membrane-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0043014-&&-alpha-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0042802-&&-identical protein binding	G:9606:OFD1				OFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OFD1	0.43268116	0.07344347	169	4	FALSE	OFD1	OFD1	99.62874251	0	168	0	0.78147156	FALSE	1	OFD1	1219898	0.02358768
788055	taxon:9606	2.22530329	3.00E-04	178303	1902	ribosomal protein L11	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL11			KEGG-&-1&-hsa03010-&&-Ribosome	RPL11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL11	0.44937695	0.38587111	168	4	FALSE	RPL11	RPL11	206.0119048	0	168	0	0.79578278	FALSE	0	RPL11	774538	0.04327731
789479	taxon:9606	2.31369151	7.45E-04	175375	1902	nuclear receptor corepressor 1	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0072368-&&-regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051225-&&-spindle assembly-%%-GO:0072362-&&-regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000191-&&-regulation of fatty acid transport-%%-GO:0007623-&&-circadian rhythm-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:NCOR1	NCOR1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance	NCOR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOR1	0.43220974	0.14100037	168	4	FALSE	NCOR1	NCOR1	146.5662651	0	167	0	0.78105142	FALSE	1	NCOR1	1405496	0.03479159
792635	taxon:9606	2.18055774	0.00105689	181679	1902	eukaryotic translation elongation factor 2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0051593-&&-response to folic acid-%%-GO:0017183-&&-peptidyl-diphthamide biosynthetic process from peptidyl-histidine-%%-GO:0045727-&&-positive regulation of translation-%%-GO:2000767-&&-positive regulation of cytoplasmic translation-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0002931-&&-response to ischemia-%%-GO:0006414-&&-translational elongation-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042788-&&-polysomal ribosome|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0008097-&&-5S rRNA binding	G:9606:EEF2			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	EEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF2	0.45859827	0.15458196	168	4	FALSE	EEF2	EEF2	189.0481928	0	167	0	0.80324038	FALSE	1	EEF2	1640344	0.03749349
792680	taxon:9606	2.22293997	6.54E-04	181574	1902	drebrin 1	gene	biological_process-&-1&-GO:0032507-&&-maintenance of protein location in cell-%%-GO:0050773-&&-regulation of dendrite development-%%-GO:0010644-&&-cell communication by electrical coupling-%%-GO:0010643-&&-cell communication by chemical coupling-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0007015-&&-actin filament organization-%%-GO:0061351-&&-neural precursor cell proliferation|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005921-&&-gap junction-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0042641-&&-actomyosin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005522-&&-profilin binding	G:9606:DBN1				DBN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBN1	0.4498547	0.12230741	168	4	FALSE	DBN1	DBN1	149.060241	0	167	0	0.79617667	FALSE	1	DBN1	1316628	0.03124826
787096	taxon:9606	2.19379234	0.00156786	180063	1902	inhibitor of nuclear factor kappa B kinase subunit beta	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903347-&&-negative regulation of bicellular tight junction assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0042501-&&-serine phosphorylation of STAT protein-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0009615-&&-response to virus-%%-GO:0035509-&&-negative regulation of myosin-light-chain-phosphatase activity-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005634-&&-nucleus-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:IKBKB	IKBKB	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	IKBKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKB	0.45583166	0.09389496	166	4	FALSE	IKBKB	IKBKB	133.4573171	0	165	0	0.80103461	FALSE	1	IKBKB	2006686	0.02689341
788818	taxon:9606	2.31589727	9.17E-04	176815	1902	ubiquitin conjugating enzyme E2 D3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2D3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2D3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2D3	0.43179808	0.04810714	166	4	FALSE	UBE2D3	UBE2D3	108.847561	0	165	0	0.78068379	FALSE	1	UBE2D3	1471018	0.02597249
790285	taxon:9606	2.25082716	5.01E-04	173429	1902	splicing factor 3b subunit 1	gene	biological_process-&-1&-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0034693-&&-U11/U12 snRNP-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B1	SF3B1	TRUE	KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B1	0.44428111	0.18116101	166	4	FALSE	SF3B1	SF3B1	200.7590361	0	166	0	0.79152881	FALSE	0	SF3B1	1163170	0.04358642
793361	taxon:9606	2.18402395	5.68E-04	180236	1902	heterogeneous nuclear ribonucleoprotein H1	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006396-&&-RNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH1				HNRNPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH1	0.45787044	0.17517342	166	4	FALSE	HNRNPH1	HNRNPH1	210.6746988	0	166	0	0.80266268	FALSE	0	HNRNPH1	1284532	0.04194796
789723	taxon:9606	2.16826847	7.15E-04	174823	1902	chaperonin containing TCP1 subunit 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0051086-&&-chaperone mediated protein folding independent of cofactor-%%-GO:0050821-&&-protein stabilization-%%-GO:1901998-&&-toxin transport-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CCT2				CCT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT2	0.4611975	0.14693274	165	4	FALSE	CCT2	CCT2	198.3272727	0	165	0	0.80528859	FALSE	0	CCT2	1673466	0.03873343
793174	taxon:9606	2.29336695	0.00149256	180588	1902	golgin A2	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0051297-&&-centrosome organization-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0006486-&&-protein glycosylation-%%-GO:0051225-&&-spindle assembly-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0060050-&&-positive regulation of protein glycosylation-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0090306-&&-spindle assembly involved in meiosis-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0000137-&&-Golgi cis cisterna-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0000922-&&-spindle pole-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0061676-&&-importin-alpha family protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0019905-&&-syntaxin binding	G:9606:GOLGA2				GOLGA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLGA2	0.43604012	0.03074649	165	4	FALSE	GOLGA2	GOLGA2	96.01818182	0	165	0	0.78443884	FALSE	0	GOLGA2	1802672	0.02220164
792297	taxon:9606	2.20797227	0.00157577	182275	1902	cyclin dependent kinase inhibitor 2A	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0035986-&&-senescence-associated heterochromatin focus assembly-%%-GO:0090399-&&-replicative senescence-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:2000111-&&-positive regulation of macrophage apoptotic process-%%-GO:0090398-&&-cellular senescence|cellular_component-&-1&-GO:0035985-&&-senescence-associated heterochromatin focus-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CDKN2A			KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma	CDKN2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN2A	0.45290424	0.07376927	164	4	FALSE	CDKN2A	CDKN2A	142.1707317	0	164	0	0.79867129	FALSE	0	CDKN2A	1963422	0.02921315
793360	taxon:9606	2.17787931	4.09E-04	180242	1902	heterogeneous nuclear ribonucleoprotein A2/B1	gene	biological_process-&-1&-GO:1990428-&&-miRNA transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1905663-&&-positive regulation of telomerase RNA reverse transcriptase activity-%%-GO:0044806-&&-G-quadruplex DNA unwinding-%%-GO:0050658-&&-RNA transport-%%-GO:0010467-&&-gene expression-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:1904358-&&-positive regulation of telomere maintenance via telomere lengthening-%%-GO:0031053-&&-primary miRNA processing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015030-&&-Cajal body-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0097157-&&-pre-mRNA intronic binding	G:9606:HNRNPA2B1				HNRNPA2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA2B1	0.45916227	0.17644352	164	4	FALSE	HNRNPA2B1	HNRNPA2B1	216.4938272	0	163	0	0.80368678	FALSE	1	HNRNPA2B1	1098948	0.04275755
787229	taxon:9606	2.18969592	7.96E-04	179831	1902	minichromosome maintenance complex component 7	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0042493-&&-response to drug-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM7			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM7	0.45668442	0.14642857	163	4	FALSE	MCM7	MCM7	204.5403727	0	162	0	0.80171735	FALSE	1	MCM7	1614416	0.04095598
788159	taxon:9606	2.28879786	0.00140772	178145	1902	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0051668-&&-localization within membrane-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0048870-&&-cell motility-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0031529-&&-ruffle organization-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0007411-&&-axon guidance-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0010310-&&-regulation of hydrogen peroxide metabolic process-%%-GO:0031295-&&-T cell costimulation-%%-GO:0045453-&&-bone resorption-%%-GO:0030168-&&-platelet activation-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0021831-&&-embryonic olfactory bulb interneuron precursor migration-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0043652-&&-engulfment of apoptotic cell-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0007155-&&-cell adhesion-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032707-&&-negative regulation of interleukin-23 production-%%-GO:0048532-&&-anatomical structure arrangement-%%-GO:0014041-&&-regulation of neuron maturation-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0021799-&&-cerebral cortex radially oriented cell migration-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0060263-&&-regulation of respiratory burst-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0097178-&&-ruffle assembly-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0008361-&&-regulation of cell size-%%-GO:0002093-&&-auditory receptor cell morphogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0021894-&&-cerebral cortex GABAergic interneuron development-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0051932-&&-synaptic transmission, GABAergic|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043197-&&-dendritic spine-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005925-&&-focal adhesion-%%-GO:0000242-&&-pericentriolar material-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0060091-&&-kinocilium-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001891-&&-phagocytic cup-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0042470-&&-melanosome-%%-GO:0030027-&&-lamellipodium-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051022-&&-Rho GDP-dissociation inhibitor binding	G:9606:RAC1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	RAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAC1	0.43691058	0.05201863	163	4	FALSE	RAC1	RAC1	123.0869565	0	162	0	0.78520036	FALSE	1	RAC1	1864770	0.02829903
792673	taxon:9606	2.26563731	9.27E-04	181582	1902	death domain associated protein	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0016032-&&-viral process-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0072738-&&-cellular response to diamide-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0034620-&&-cellular response to unfolded protein|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016604-&&-nuclear body-%%-GO:0070603-&&-SWI/SNF superfamily-type complex|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0002039-&&-p53 binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding	G:9606:DAXX			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	DAXX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAXX	0.44137691	0.11055901	163	4	FALSE	DAXX	DAXX	153.6832298	0	162	0	0.78906045	FALSE	1	DAXX	1580304	0.03404932
792686	taxon:9606	2.29336695	0.00132172	181563	1902	dynactin subunit 1	gene	biological_process-&-1&-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0010970-&&-transport along microtubule-%%-GO:0007399-&&-nervous system development-%%-GO:0090063-&&-positive regulation of microtubule nucleation-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032402-&&-melanosome transport|cellular_component-&-1&-GO:0005869-&&-dynactin complex-%%-GO:0000776-&&-kinetochore-%%-GO:0005874-&&-microtubule-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0030904-&&-retromer complex-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0030286-&&-dynein complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005813-&&-centrosome-%%-GO:0031252-&&-cell leading edge-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0070840-&&-dynein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0003774-&&-motor activity-%%-GO:0015631-&&-tubulin binding	G:9606:DCTN1	DCTN1	TRUE	KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05016-&&-Huntington disease	DCTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCTN1	0.43604012	0.04021739	163	4	FALSE	DCTN1	DCTN1	95.74534161	0	162	0	0.78443884	FALSE	1	DCTN1	1512690	0.02209918
788052	taxon:9606	2.27225461	2.15E-04	178306	1902	ribosomal protein L8	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:1990932-&&-5.8S rRNA binding	G:9606:RPL8			KEGG-&-1&-hsa03010-&&-Ribosome	RPL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL8	0.44009153	0.3898474	162	4	FALSE	RPL8	RPL8	206.8148148	0	162	0	0.78795757	FALSE	0	RPL8	588850	0.04622593
788702	taxon:9606	2.22010399	6.88E-04	177153	1902	topoisomerase (DNA) I	gene	biological_process-&-1&-GO:0016310-&&-phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006265-&&-DNA topological change-%%-GO:0007623-&&-circadian rhythm-%%-GO:0016032-&&-viral process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006260-&&-DNA replication-%%-GO:0012501-&&-programmed cell death-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032922-&&-circadian regulation of gene expression|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0000932-&&-P-body-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003917-&&-DNA topoisomerase type I activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding	G:9606:TOP1	TOP1	TRUE		TOP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOP1	0.45042935	0.15566038	162	4	FALSE	TOP1	TOP1	201.68125	0	161	0	0.79664934	FALSE	1	TOP1	1347608	0.04202047
788903	taxon:9606	2.2106507	0.00115035	176647	1902	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0006713-&&-glucocorticoid catabolic process-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0014704-&&-intercalated disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:YWHAH			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis	YWHAH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YWHAH	0.4523555	0.08915094	162	4	FALSE	YWHAH	YWHAH	144.43125	0	161	0	0.79822488	FALSE	1	YWHAH	1770724	0.02971805
789500	taxon:9606	2.35434063	9.90E-04	175335	1902	IQ motif containing B1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0048496-&&-maintenance of animal organ identity-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0045494-&&-photoreceptor cell maintenance|cellular_component-&-1&-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium|molecular_function-&-1&-GO:0005516-&&-calmodulin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:IQCB1				IQCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQCB1	0.42474737	0.04110114	162	4	FALSE	IQCB1	IQCB1	94.61111111	0	162	0	0.77427656	FALSE	0	IQCB1	1381602	0.02401821
789888	taxon:9606	2.25445092	6.41E-04	174420	1902	activator of HSP90 ATPase activity 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:AHSA1	AHSA1	TRUE		AHSA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHSA1	0.44356699	0.10497661	162	4	FALSE	AHSA1	AHSA1	149.4135803	0	162	0	0.79092485	FALSE	0	AHSA1	1045880	0.03258478
787173	taxon:9606	2.21222625	0.00165999	179926	1902	LYN proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0009743-&&-response to carbohydrate-%%-GO:0070447-&&-positive regulation of oligodendrocyte progenitor proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0090025-&&-regulation of monocyte chemotaxis-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0070668-&&-positive regulation of mast cell proliferation-%%-GO:0034136-&&-negative regulation of toll-like receptor 2 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0034144-&&-negative regulation of toll-like receptor 4 signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0002762-&&-negative regulation of myeloid leukocyte differentiation-%%-GO:0032868-&&-response to insulin-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0002513-&&-tolerance induction to self antigen-%%-GO:0050855-&&-regulation of B cell receptor signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0002768-&&-immune response-regulating cell surface receptor signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0016032-&&-viral process-%%-GO:0043200-&&-response to amino acid-%%-GO:0070667-&&-negative regulation of mast cell proliferation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0002774-&&-Fc receptor mediated inhibitory signaling pathway-%%-GO:0070304-&&-positive regulation of stress-activated protein kinase signaling cascade-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0050663-&&-cytokine secretion-%%-GO:0009636-&&-response to toxic substance-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0007417-&&-central nervous system development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0060369-&&-positive regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0031175-&&-neuron projection development-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0002902-&&-regulation of B cell apoptotic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0033003-&&-regulation of mast cell activation-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0009725-&&-response to hormone-%%-GO:0002431-&&-Fc receptor mediated stimulatory signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:2000670-&&-positive regulation of dendritic cell apoptotic process-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002553-&&-histamine secretion by mast cell-%%-GO:0042493-&&-response to drug-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006991-&&-response to sterol depletion-%%-GO:0007596-&&-blood coagulation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0048678-&&-response to axon injury-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:0042531-&&-positive regulation of tyrosine phosphorylation of STAT protein-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1902532-&&-negative regulation of intracellular signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030061-&&-mitochondrial crista-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034666-&&-integrin alpha2-beta1 complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0042629-&&-mast cell granule-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0043208-&&-glycosphingolipid binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding	G:9606:LYN			KEGG-&-1&-hsa04730-&&-Long-term depression-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04611-&&-Platelet activation-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	LYN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYN	0.45203333	0.06599793	161	4	FALSE	LYN	LYN	117.1509434	0	160	0	0.79796229	FALSE	1	LYN	2023276	0.024162
787593	taxon:9606	2.33637939	7.58E-04	179127	1902	neurofibromin 2	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0001707-&&-mesoderm formation-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0035330-&&-regulation of hippo signaling-%%-GO:0014010-&&-Schwann cell proliferation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0014013-&&-regulation of gliogenesis-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0007398-&&-ectoderm development-%%-GO:0042524-&&-negative regulation of tyrosine phosphorylation of Stat5 protein|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005912-&&-adherens junction-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0032587-&&-ruffle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:NF2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction	NF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NF2	0.42801268	0.04585622	161	4	FALSE	NF2	NF2	108.2704403	0	160	0	0.7772701	FALSE	1	NF2	1073628	0.02663315
787892	taxon:9606	2.21837088	9.69E-04	178648	1902	proteasome 26S subunit, ATPase 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0090261-&&-positive regulation of inclusion body assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016234-&&-inclusion body-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0098794-&&-postsynapse-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031531-&&-thyrotropin-releasing hormone receptor binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:PSMC5			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC5	0.45078125	0.15587931	161	4	FALSE	PSMC5	PSMC5	159.6352201	0	160	0	0.79693819	FALSE	1	PSMC5	1534178	0.03317048
787965	taxon:9606	2.16590515	0.0011546	178492	1902	poly(rC) binding protein 1	gene	biological_process-&-1&-GO:0039694-&&-viral RNA genome replication-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0098847-&&-sequence-specific single stranded DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PCBP1			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa04216-&&-Ferroptosis	PCBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBP1	0.46170073	0.10768634	161	4	FALSE	PCBP1	PCBP1	178.8695652	0	161	0	0.80568247	FALSE	0	PCBP1	1826242	0.0348063
788280	taxon:9606	2.24610052	3.48E-04	177959	1902	ribosomal protein S10	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS10			KEGG-&-1&-hsa03010-&&-Ribosome	RPS10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS10	0.44521605	0.3552795	161	4	FALSE	RPS10	RPS10	216.5465839	0	161	0	0.79231658	FALSE	0	RPS10	844788	0.04673735
789496	taxon:9606	2.31700016	5.59E-04	175336	1902	mediator of DNA damage checkpoint 1	gene	biological_process-&-1&-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0031573-&&-intra-S DNA damage checkpoint|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005694-&&-chromosome|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070975-&&-FHA domain binding-%%-GO:0005515-&&-protein binding	G:9606:MDC1				MDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDC1	0.43159255	0.08454741	161	4	FALSE	MDC1	MDC1	130.5408805	0	160	0	0.78049997	FALSE	1	MDC1	972176	0.0311048
793244	taxon:9606	2.42114385	9.27E-04	180462	1902	intercellular adhesion molecule 1	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0097368-&&-establishment of Sertoli cell barrier-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0046813-&&-receptor-mediated virion attachment to host cell-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0010477-&&-response to sulfur dioxide-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0032868-&&-response to insulin-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0002457-&&-T cell antigen processing and presentation-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0001975-&&-response to amphetamine-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0050776-&&-regulation of immune response-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0034698-&&-response to gonadotropin-%%-GO:0043200-&&-response to amino acid-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0002438-&&-acute inflammatory response to antigenic stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0002291-&&-T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0044406-&&-adhesion of symbiont to host-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0002693-&&-positive regulation of cellular extravasation-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0001910-&&-regulation of leukocyte mediated cytotoxicity-%%-GO:0007569-&&-cell aging-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0007155-&&-cell adhesion-%%-GO:0046688-&&-response to copper ion-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061028-&&-establishment of endothelial barrier|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0045121-&&-membrane raft-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0001618-&&-virus receptor activity	G:9606:ICAM1	ICAM1	TRUE	KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05416-&&-Viral myocarditis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	ICAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICAM1	0.41302792	0.14767932	161	4	FALSE	ICAM1	ICAM1	147.4213837	0	160	0	0.76314269	FALSE	1	ICAM1	2063890	0.04176586
787311	taxon:9606	2.16322672	9.50E-04	179682	1902	karyopherin subunit alpha 2	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0006607-&&-NLS-bearing protein import into nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:KPNA2			KEGG-&-1&-hsa05164-&&-Influenza A	KPNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA2	0.4622724	0.08780134	160	4	FALSE	KPNA2	KPNA2	180.4556962	0	159	0	0.80612888	FALSE	1	KPNA2	1674834	0.03499671
787602	taxon:9606	2.2089176	0.00141163	179112	1902	NFKB inhibitor alpha	gene	biological_process-&-1&-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0097421-&&-liver regeneration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0070427-&&-nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0006915-&&-apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0070417-&&-cellular response to cold-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0010875-&&-positive regulation of cholesterol efflux|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding	G:9606:NFKBIA	NFKBIA	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	NFKBIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIA	0.45271041	0.08449569	160	4	FALSE	NFKBIA	NFKBIA	143.1012658	0	159	0	0.79851373	FALSE	1	NFKBIA	1752254	0.02942953
788422	taxon:9606	2.20450607	5.03E-04	177697	1902	splicing factor proline and glutamine rich	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045876-&&-positive regulation of sister chromatid cohesion-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0008380-&&-RNA splicing-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006397-&&-mRNA processing-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:SFPQ				SFPQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFPQ	0.45361635	0.14730307	160	4	FALSE	SFPQ	SFPQ	195.2658228	0	159	0	0.79924899	FALSE	1	SFPQ	1094426	0.0398232
788856	taxon:9606	2.27146683	7.55E-04	176744	1902	vinculin	gene	biological_process-&-1&-GO:0034333-&&-adherens junction assembly-%%-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0048675-&&-axon extension-%%-GO:0070527-&&-platelet aggregation-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006936-&&-muscle contraction-%%-GO:0043297-&&-apical junction assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007155-&&-cell adhesion-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0007160-&&-cell-matrix adhesion|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0043034-&&-costamere-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0002102-&&-podosome-%%-GO:0030055-&&-cell-substrate junction-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0002162-&&-dystroglycan binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding	G:9606:VCL			KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction-%%-hsa05131-&&-Shigellosis	VCL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCL	0.44024416	0.09263888	160	4	FALSE	VCL	VCL	138.4556962	0	159	0	0.78808886	FALSE	1	VCL	1188250	0.03096042
792321	taxon:9606	2.28123523	0.00103813	182236	1902	cystic fibrosis transmembrane conductance regulator	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0061024-&&-membrane organization-%%-GO:1902161-&&-positive regulation of cyclic nucleotide-gated ion channel activity-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0051454-&&-intracellular pH elevation-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0006810-&&-transport-%%-GO:0099133-&&-ATP hydrolysis coupled anion transmembrane transport-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030301-&&-cholesterol transport-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0048240-&&-sperm capacitation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:1902943-&&-positive regulation of voltage-gated chloride channel activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0034707-&&-chloride channel complex-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031205-&&-endoplasmic reticulum Sec complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0015106-&&-bicarbonate transmembrane transporter activity-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0043225-&&-ATPase-coupled anion transmembrane transporter activity-%%-GO:0005254-&&-chloride channel activity-%%-GO:0005260-&&-intracellular ATPase-gated chloride channel activity-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0015108-&&-chloride transmembrane transporter activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0019869-&&-chloride channel inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding	G:9606:CFTR			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa02010-&&-ABC transporters-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04530-&&-Tight junction-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04972-&&-Pancreatic secretion	CFTR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFTR	0.438359	0.04539224	160	4	FALSE	CFTR	CFTR	104.5	0	159	0	0.7864608	FALSE	1	CFTR	1342648	0.02371406
787592	taxon:9606	2.31243107	6.75E-04	179125	1902	nuclear factor of activated T-cells 2	gene	biological_process-&-1&-GO:0001816-&&-cytokine production-%%-GO:0016477-&&-cell migration-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042493-&&-response to drug-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0014904-&&-myotube cell development-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0044798-&&-nuclear transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:NFATC2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NFATC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC2	0.43244532	0.06385759	159	4	FALSE	NFATC2	NFATC2	122.8853503	0	158	0	0.78126149	FALSE	1	NFATC2	1100998	0.02901594
788279	taxon:9606	2.26406176	1.65E-04	177956	1902	ribosomal protein S13	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070181-&&-small ribosomal subunit rRNA binding-%%-GO:1990932-&&-5.8S rRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS13			KEGG-&-1&-hsa03010-&&-Ribosome	RPS13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS13	0.44168406	0.41437784	159	4	FALSE	RPS13	RPS13	207.3899371	0	159	0	0.78932304	FALSE	0	RPS13	567456	0.04583203
788370	taxon:9606	2.21837088	0.00110699	177788	1902	SRSF protein kinase 1	gene	biological_process-&-1&-GO:0035092-&&-sperm chromatin condensation-%%-GO:0045087-&&-innate immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:SRPK1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	SRPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPK1	0.45078125	0.10182917	159	4	FALSE	SRPK1	SRPK1	144.5732484	0	158	0	0.79693819	FALSE	1	SRPK1	1480494	0.0300341
788827	taxon:9606	2.27792658	7.76E-04	176800	1902	small ubiquitin-like modifier 1	gene	biological_process-&-1&-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050821-&&-protein stabilization-%%-GO:0045759-&&-negative regulation of action potential-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0060021-&&-palate development-%%-GO:0032880-&&-regulation of protein localization-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:0016925-&&-protein sumoylation-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0090204-&&-protein localization to nuclear pore-%%-GO:1901896-&&-positive regulation of calcium-transporting ATPase activity-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0030578-&&-PML body organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034605-&&-cellular response to heat-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0001741-&&-XY body-%%-GO:0016605-&&-PML body-%%-GO:0016607-&&-nuclear speck-%%-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000792-&&-heterochromatin-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097165-&&-nuclear stress granule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0031386-&&-protein tag	G:9606:SUMO1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO1	0.43899571	0.07765801	159	4	FALSE	SUMO1	SUMO1	124.7834395	0	158	0	0.78701224	FALSE	1	SUMO1	1220842	0.02806359
789251	taxon:9606	2.30439578	0.00103968	175895	1902	dynein light chain LC8-type 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0035721-&&-intraciliary retrograde transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0044458-&&-motile cilium assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0097542-&&-ciliary tip-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003774-&&-motor activity	G:9606:DYNLL1			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption	DYNLL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNLL1	0.43395323	0.04695411	159	4	FALSE	DYNLL1	DYNLL1	108.3757962	0	158	0	0.7826007	FALSE	1	DYNLL1	1304676	0.02539408
789662	taxon:9606	2.2635891	5.13E-04	174950	1902	protein arginine methyltransferase 5	gene	biological_process-&-1&-GO:0019918-&&-peptidyl-arginine methylation, to symmetrical-dimethyl arginine-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0097421-&&-liver regeneration-%%-GO:0043985-&&-histone H4-R3 methylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:1904992-&&-positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034709-&&-methylosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0035243-&&-protein-arginine omega-N symmetric methyltransferase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0008327-&&-methyl-CpG binding	G:9606:PRMT5			KEGG-&-1&-hsa03013-&&-RNA transport	PRMT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT5	0.44177629	0.12869508	159	4	FALSE	PRMT5	PRMT5	180.4522293	0	158	0	0.78940182	FALSE	1	PRMT5	1180008	0.03986732
789837	taxon:9606	2.34709311	5.20E-04	174542	1902	RNA binding protein with serine rich domain 1	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0061574-&&-ASAP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding	G:9606:RNPS1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	RNPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNPS1	0.42605894	0.14218613	159	4	FALSE	RNPS1	RNPS1	140.3018868	0	159	0	0.77548448	FALSE	0	RNPS1	862390	0.03494286
791099	taxon:9606	2.31085552	0.00111868	170055	1902	F-box and WD repeat domain containing 7	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:1902806-&&-regulation of cell cycle G1/S phase transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001944-&&-vasculature development-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:2000346-&&-negative regulation of hepatocyte proliferation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0016032-&&-viral process-%%-GO:0010868-&&-negative regulation of triglyceride biosynthetic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:2000639-&&-negative regulation of SREBP signaling pathway-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0010883-&&-regulation of lipid storage-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:1903378-&&-positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990452-&&-Parkin-FBXW7-Cul1 ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0050816-&&-phosphothreonine binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042802-&&-identical protein binding	G:9606:FBXW7			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	FBXW7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW7	0.43274016	0.04940389	159	4	FALSE	FBXW7	FBXW7	93.60509554	0	158	0	0.78152408	FALSE	1	FBXW7	1293526	0.02208329
792134	taxon:9606	2.22120687	7.38E-04	182533	1902	actin gamma 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051592-&&-response to calcium ion-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0045214-&&-sarcomere organization-%%-GO:0034329-&&-cell junction assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005634-&&-nucleus-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097433-&&-dense body-%%-GO:0030016-&&-myofibril-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042802-&&-identical protein binding	G:9606:ACTG1			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05132-&&-Salmonella infection-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05416-&&-Viral myocarditis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	ACTG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTG1	0.4502057	0.09741957	159	4	FALSE	ACTG1	ACTG1	171.7515924	0	158	0	0.79646552	FALSE	1	ACTG1	1555912	0.03584614
793140	taxon:9606	2.37025366	7.41E-04	164279	1902	centrosomal protein 128	gene	cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0000922-&&-spindle pole	G:9606:CEP128				CEP128	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP128	0.42189577	0.07515325	159	4	FALSE	CEP128	CEP128	79.14465409	0	159	0	0.77162439	FALSE	0	CEP128	952626	0.02048462
787871	taxon:9606	2.26500709	8.35E-04	178671	1902	proteasome subunit alpha 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA1			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA1	0.44149972	0.13680728	158	4	FALSE	PSMA1	PSMA1	130.1666667	0	157	0	0.78916549	FALSE	1	PSMA1	1328164	0.02877528
788050	taxon:9606	2.24121632	1.28E-04	178307	1902	ribosomal protein L7a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0042788-&&-polysomal ribosome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL7A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL7A	0.44618629	0.43094413	158	4	FALSE	RPL7A	RPL7A	232.0886076	0	158	0	0.79313061	FALSE	0	RPL7A	526466	0.0496765
788060	taxon:9606	2.25902001	1.31E-04	178298	1902	ribosomal protein L18	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL18			KEGG-&-1&-hsa03010-&&-Ribosome	RPL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL18	0.44266983	0.44924615	158	4	FALSE	RPL18	RPL18	222.6582279	0	158	0	0.79016333	FALSE	0	RPL18	521810	0.04884998
788281	taxon:9606	2.26563731	2.09E-04	177958	1902	ribosomal protein S11	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS11			KEGG-&-1&-hsa03010-&&-Ribosome	RPS11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS11	0.44137691	0.39635572	158	4	FALSE	RPS11	RPS11	205.0759494	0	158	0	0.78906045	FALSE	0	RPS11	615056	0.04539087
788282	taxon:9606	2.28911297	1.67E-04	177953	1902	ribosomal protein S15a	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0009615-&&-response to virus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS15A			KEGG-&-1&-hsa03010-&&-Ribosome	RPS15A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS15A	0.43685044	0.41497105	158	4	FALSE	RPS15A	RPS15A	196.0576923	0	157	0	0.78514784	FALSE	1	RPS15A	462670	0.04484247
788507	taxon:9606	2.43359067	0.00168674	177535	1902	superoxide dismutase 1	gene	biological_process-&-1&-GO:0042554-&&-superoxide anion generation-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0048678-&&-response to axon injury-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0001975-&&-response to amphetamine-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0007626-&&-locomotory behavior-%%-GO:0001895-&&-retina homeostasis-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0046677-&&-response to antibiotic-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0034465-&&-response to carbon monoxide-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0060087-&&-relaxation of vascular smooth muscle-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0060047-&&-heart contraction-%%-GO:0001890-&&-placenta development-%%-GO:0002576-&&-platelet degranulation-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:0050665-&&-hydrogen peroxide biosynthetic process-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0042493-&&-response to drug-%%-GO:0046620-&&-regulation of organ growth-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007566-&&-embryo implantation-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0097332-&&-response to antipsychotic drug-%%-GO:0045471-&&-response to ethanol-%%-GO:0007569-&&-cell aging-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0046688-&&-response to copper ion-%%-GO:0060052-&&-neurofilament cytoskeleton organization-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0009408-&&-response to heat-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0010033-&&-response to organic substance-%%-GO:0000303-&&-response to superoxide-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0048538-&&-thymus development-%%-GO:0045541-&&-negative regulation of cholesterol biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031045-&&-dense core granule-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005777-&&-peroxisome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004784-&&-superoxide dismutase activity-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:SOD1	SOD1	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa05016-&&-Huntington disease-%%-hsa05020-&&-Prion diseases-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04213-&&-Longevity regulating pathway - multiple species	SOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOD1	0.41091545	0.0573201	158	4	FALSE	SOD1	SOD1	73.55769231	0	157	0	0.76106822	FALSE	1	SOD1	1818600	0.02129015
787630	taxon:9606	2.24357964	8.46E-04	179063	1902	notch 1	gene	biological_process-&-1&-GO:1901201-&&-regulation of extracellular matrix assembly-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0003192-&&-mitral valve formation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0006955-&&-immune response-%%-GO:0014807-&&-regulation of somitogenesis-%%-GO:0042246-&&-tissue regeneration-%%-GO:0045608-&&-negative regulation of auditory receptor cell differentiation-%%-GO:0060768-&&-regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030324-&&-lung development-%%-GO:0001708-&&-cell fate specification-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0072017-&&-distal tubule development-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0046533-&&-negative regulation of photoreceptor cell differentiation-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0003162-&&-atrioventricular node development-%%-GO:0003169-&&-coronary vein morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2001027-&&-negative regulation of endothelial cell chemotaxis-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0035148-&&-tube formation-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0045603-&&-positive regulation of endothelial cell differentiation-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0048103-&&-somatic stem cell division-%%-GO:0003157-&&-endocardium development-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0003207-&&-cardiac chamber formation-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021515-&&-cell differentiation in spinal cord-%%-GO:0060979-&&-vasculogenesis involved in coronary vascular morphogenesis-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0003209-&&-cardiac atrium morphogenesis-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0007386-&&-compartment pattern specification-%%-GO:1902263-&&-apoptotic process involved in embryonic digit morphogenesis-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0007507-&&-heart development-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0007440-&&-foregut morphogenesis-%%-GO:0009912-&&-auditory receptor cell fate commitment-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0003180-&&-aortic valve morphogenesis-%%-GO:0006959-&&-humoral immune response-%%-GO:0003219-&&-cardiac right ventricle formation-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:1903849-&&-positive regulation of aorta morphogenesis-%%-GO:0060842-&&-arterial endothelial cell differentiation-%%-GO:0030900-&&-forebrain development-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0060843-&&-venous endothelial cell differentiation-%%-GO:0070986-&&-left/right axis specification-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0007409-&&-axonogenesis-%%-GO:0031960-&&-response to corticosteroid-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:2000974-&&-negative regulation of pro-B cell differentiation-%%-GO:0003273-&&-cell migration involved in endocardial cushion formation-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0003270-&&-Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation-%%-GO:0060956-&&-endocardial cell differentiation-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0003256-&&-regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:0060948-&&-cardiac vascular smooth muscle cell development-%%-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0003213-&&-cardiac right atrium morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0072044-&&-collecting duct development-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0003160-&&-endocardium morphogenesis-%%-GO:0072144-&&-glomerular mesangial cell development-%%-GO:0021915-&&-neural tube development-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0007492-&&-endoderm development-%%-GO:0001947-&&-heart looping-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0003344-&&-pericardium morphogenesis-%%-GO:0003241-&&-growth involved in heart morphogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0001889-&&-liver development-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005912-&&-adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus-%%-GO:0002193-&&-MAML1-RBP-Jkappa- ICN1 complex-%%-GO:0009986-&&-cell surface-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004872-&&-receptor activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0005112-&&-Notch binding	G:9606:NOTCH1	NOTCH1	TRUE	KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05020-&&-Prion diseases-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	NOTCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH1	0.44571629	0.05890841	156	4	FALSE	NOTCH1	NOTCH1	125.6688312	0	155	0	0.79273673	FALSE	1	NOTCH1	1221074	0.02700115
787900	taxon:9606	2.20277296	5.88E-04	178643	1902	proteasome 26S subunit, non-ATPase 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0005634-&&-nucleus-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:PSMD4			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD4	0.45397325	0.16781258	156	4	FALSE	PSMD4	PSMD4	172.7597403	0	155	0	0.79953784	FALSE	1	PSMD4	1253604	0.03517812
788287	taxon:9606	2.23979833	2.87E-04	177948	1902	ribosomal protein S19	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0007000-&&-nucleolus organization-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0060265-&&-positive regulation of respiratory burst involved in inflammatory response-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0060266-&&-negative regulation of respiratory burst involved in inflammatory response-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0009991-&&-response to extracellular stimulus-%%-GO:0019083-&&-viral transcription-%%-GO:0051262-&&-protein tetramerization-%%-GO:0007219-&&-Notch signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017134-&&-fibroblast growth factor binding	G:9606:RPS19			KEGG-&-1&-hsa03010-&&-Ribosome	RPS19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS19	0.44646877	0.38171632	156	4	FALSE	RPS19	RPS19	204.6883117	0	155	0	0.79336695	FALSE	1	RPS19	703496	0.04372748
789378	taxon:9606	2.22955727	7.19E-04	175627	1902	aurora kinase B	gene	biological_process-&-1&-GO:0051256-&&-mitotic spindle midzone assembly-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0036089-&&-cleavage furrow formation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0031577-&&-spindle checkpoint-%%-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0016570-&&-histone modification-%%-GO:0008283-&&-cell proliferation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009838-&&-abscission-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0034501-&&-protein localization to kinetochore-%%-GO:0007051-&&-spindle organization-%%-GO:0043988-&&-histone H3-S28 phosphorylation-%%-GO:0032466-&&-negative regulation of cytokinesis-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0007568-&&-aging-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0051233-&&-spindle midzone-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0005876-&&-spindle microtubule-%%-GO:0010369-&&-chromocenter-%%-GO:0030496-&&-midbody-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000779-&&-condensed chromosome, centromeric region|molecular_function-&-1&-GO:0035174-&&-histone serine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:AURKB				AURKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AURKB	0.44851954	0.09438927	156	4	FALSE	AURKB	AURKB	170.2597403	0	155	0	0.79507379	FALSE	1	AURKB	1321270	0.03582017
790286	taxon:9606	2.26264377	4.75E-04	173430	1902	splicing factor 3b subunit 3	gene	biological_process-&-1&-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006461-&&-protein complex assembly-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B3			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B3	0.44196087	0.19702233	156	4	FALSE	SF3B3	SF3B3	198.3525641	0	156	0	0.78955937	FALSE	0	SF3B3	986634	0.04370501
790889	taxon:9606	2.22467307	7.51E-04	170766	1902	LIM domain and actin binding 1	gene	biological_process-&-1&-GO:0030835-&&-negative regulation of actin filament depolymerization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0031529-&&-ruffle organization|cellular_component-&-1&-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0032154-&&-cleavage furrow-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:LIMA1				LIMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIMA1	0.44950425	0.1490488	156	4	FALSE	LIMA1	LIMA1	173.2692308	0	156	0	0.79588782	FALSE	0	LIMA1	1466510	0.03630061
791977	taxon:9606	2.30801954	0.00129226	182782	1902	APC, WNT signaling pathway regulator	gene	biological_process-&-1&-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007050-&&-cell cycle arrest-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007155-&&-cell adhesion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005813-&&-centrosome-%%-GO:0016342-&&-catenin complex-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0008017-&&-microtubule binding	G:9606:APC	APC	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	APC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APC	0.4332719	0.04099822	156	4	FALSE	APC	APC	99.44805195	0	155	0	0.78199674	FALSE	1	APC	1434098	0.02345295
792279	taxon:9606	2.29636049	0.00135886	182306	1902	cell division cycle 42	gene	biological_process-&-1&-GO:0036336-&&-dendritic cell migration-%%-GO:0034613-&&-cellular protein localization-%%-GO:0031424-&&-keratinization-%%-GO:0060047-&&-heart contraction-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007097-&&-nuclear migration-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0031295-&&-T cell costimulation-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0072384-&&-organelle transport along microtubule-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0048664-&&-neuron fate determination-%%-GO:0035088-&&-establishment or maintenance of apical/basal cell polarity-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0090135-&&-actin filament branching-%%-GO:0007596-&&-blood coagulation-%%-GO:0007030-&&-Golgi organization-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0060661-&&-submandibular salivary gland formation-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0071338-&&-positive regulation of hair follicle cell proliferation-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0003334-&&-keratinocyte development-%%-GO:0060684-&&-epithelial-mesenchymal cell signaling-%%-GO:0032488-&&-Cdc42 protein signal transduction-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0046847-&&-filopodium assembly-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0099563-&&-modification of synaptic structure-%%-GO:0051835-&&-positive regulation of synapse structural plasticity-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0034332-&&-adherens junction organization-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0030496-&&-midbody-%%-GO:0043005-&&-neuron projection-%%-GO:0043209-&&-myelin sheath-%%-GO:0005925-&&-focal adhesion-%%-GO:0051233-&&-spindle midzone-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000322-&&-storage vacuole-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0031256-&&-leading edge membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030141-&&-secretory granule-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule|molecular_function-&-1&-GO:0051022-&&-Rho GDP-dissociation inhibitor binding-%%-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0034191-&&-apolipoprotein A-I receptor binding	G:9606:CDC42	CDC42	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04530-&&-Tight junction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CDC42	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC42	0.4354717	0.03879127	156	4	FALSE	CDC42	CDC42	96.42207792	0	155	0	0.78393992	FALSE	1	CDC42	1526856	0.02233875
787762	taxon:9606	2.19993698	0.00176839	178827	1902	peroxisome proliferator activated receptor gamma	gene	biological_process-&-1&-GO:0071306-&&-cellular response to vitamin E-%%-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007507-&&-heart development-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0031000-&&-response to caffeine-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0043627-&&-response to estrogen-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045165-&&-cell fate commitment-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1901558-&&-response to metformin-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000230-&&-negative regulation of pancreatic stellate cell proliferation-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0045087-&&-innate immune response-%%-GO:0010891-&&-negative regulation of sequestering of triglyceride-%%-GO:0033189-&&-response to vitamin A-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0010871-&&-negative regulation of receptor biosynthetic process-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0033993-&&-response to lipid-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0048511-&&-rhythmic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0001890-&&-placenta development-%%-GO:0007584-&&-response to nutrient-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0009409-&&-response to cold-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0046321-&&-positive regulation of fatty acid oxidation-%%-GO:0048469-&&-cell maturation-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042594-&&-response to starvation-%%-GO:0055098-&&-response to low-density lipoprotein particle-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0015909-&&-long-chain fatty acid transport-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0060694-&&-regulation of cholesterol transporter activity-%%-GO:0045713-&&-low-density lipoprotein particle receptor biosynthetic process-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0060336-&&-negative regulation of interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0050544-&&-arachidonic acid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004955-&&-prostaglandin receptor activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008144-&&-drug binding	G:9606:PPARG	PPARG	TRUE	KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04714-&&-Thermogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04211-&&-Longevity regulating pathway	PPARG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARG	0.45455848	0.07997936	155	4	FALSE	PPARG	PPARG	130.254902	0	154	0	0.8000105	FALSE	1	PPARG	2038566	0.02643841
788270	taxon:9606	2.28990074	1.67E-04	177970	1902	ribosomal protein S5	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS5			KEGG-&-1&-hsa03010-&&-Ribosome	RPS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS5	0.43670015	0.38617512	155	4	FALSE	RPS5	RPS5	203.0903226	0	155	0	0.78501654	FALSE	0	RPS5	483088	0.04650568
789918	taxon:9606	2.24074366	7.56E-04	174367	1902	KH RNA binding domain containing, signal transduction associated 1	gene	biological_process-&-1&-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0046833-&&-positive regulation of RNA export from nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0046831-&&-regulation of RNA export from nucleus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0070618-&&-Grb2-Sos complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding	G:9606:KHDRBS1				KHDRBS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KHDRBS1	0.44628041	0.10319917	155	4	FALSE	KHDRBS1	KHDRBS1	180.6339869	0	154	0	0.79320939	FALSE	1	KHDRBS1	1528056	0.0386533
790503	taxon:9606	2.30313534	6.12E-04	172661	1902	F-box protein 25	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXO25			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FBXO25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO25	0.43419072	0.05379137	155	4	FALSE	FBXO25	FBXO25	116.5032258	0	155	0	0.78281078	FALSE	0	FBXO25	924544	0.02720649
792698	taxon:9606	2.20293052	3.30E-04	181550	1902	DEAD-box helicase 3, X-linked	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0034063-&&-stress granule assembly-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0071470-&&-cellular response to osmotic stress-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0071651-&&-positive regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0045087-&&-innate immune response-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0071243-&&-cellular response to arsenic-containing substance-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042256-&&-mature ribosome assembly-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0009615-&&-response to virus-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043273-&&-CTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0017111-&&-nucleoside-triphosphatase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:DDX3X			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05161-&&-Hepatitis B	DDX3X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX3X	0.45394078	0.15232509	155	4	FALSE	DDX3X	DDX3X	217.1870968	0	155	0	0.79951158	FALSE	0	DDX3X	961206	0.0442143
793284	taxon:9606	2.35418308	4.54E-04	180378	1902	histone cluster 1 H2B family member d	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BD			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BD	0.4247758	0.02798492	155	4	FALSE	HIST1H2BD	HIST1H2BD	104.083871	0	155	0	0.77430282	FALSE	0	HIST1H2BD	1209660	0.02627275
787688	taxon:9606	2.15802741	8.44E-04	178946	1902	pyruvate kinase, muscle	gene	biological_process-&-1&-GO:0012501-&&-programmed cell death-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005929-&&-cilium-%%-GO:0031982-&&-vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004743-&&-pyruvate kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0045296-&&-cadherin binding	G:9606:PKM			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00230-&&-Purine metabolism-%%-hsa05165-&&-Human papillomavirus infection	PKM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKM	0.46338614	0.12547926	154	4	FALSE	PKM	PKM	199.9210526	0	153	0	0.80699543	FALSE	1	PKM	1549458	0.03843896
788440	taxon:9606	2.22183709	0.00104158	177668	1902	S-phase kinase associated protein 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:0031519-&&-PcG protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0097602-&&-cullin family protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:SKP1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04350-&&-TGF-beta signaling pathway	SKP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKP1	0.450078	0.08138724	154	4	FALSE	SKP1	SKP1	148.7828947	0	153	0	0.79636049	FALSE	1	SKP1	1505314	0.03097805
789176	taxon:9606	2.35465574	4.47E-04	176044	1902	histone cluster 1 H2B family member g	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BG			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BG	0.42469053	0.0280112	154	4	FALSE	HIST1H2BG	HIST1H2BG	104.4285714	0	154	0	0.77422404	FALSE	0	HIST1H2BG	1199536	0.02637802
789180	taxon:9606	2.35465574	4.47E-04	176040	1902	histone cluster 1 H2B family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BF			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BF	0.42469053	0.0280112	154	4	FALSE	HIST1H2BF	HIST1H2BF	104.4285714	0	154	0	0.77422404	FALSE	0	HIST1H2BF	1199536	0.02637802
789183	taxon:9606	2.35465574	4.47E-04	176037	1902	histone cluster 1 H2B family member i	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BI			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BI	0.42469053	0.0280112	154	4	FALSE	HIST1H2BI	HIST1H2BI	104.4285714	0	154	0	0.77422404	FALSE	0	HIST1H2BI	1199536	0.02637802
789184	taxon:9606	2.35465574	4.47E-04	176036	1902	histone cluster 1 H2B family member c	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BC			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BC	0.42469053	0.0280112	154	4	FALSE	HIST1H2BC	HIST1H2BC	104.4285714	0	154	0	0.77422404	FALSE	0	HIST1H2BC	1199536	0.02637802
789185	taxon:9606	2.35465574	4.47E-04	176039	1902	histone cluster 1 H2B family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BE	0.42469053	0.0280112	154	4	FALSE	HIST1H2BE	HIST1H2BE	104.4285714	0	154	0	0.77422404	FALSE	0	HIST1H2BE	1199536	0.02637802
789489	taxon:9606	2.31369151	8.34E-04	175355	1902	ISG15 ubiquitin-like modifier	gene	biological_process-&-1&-GO:0019941-&&-modification-dependent protein catabolic process-%%-GO:0032020-&&-ISG15-protein conjugation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0034340-&&-response to type I interferon-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0032649-&&-regulation of interferon-gamma production-%%-GO:0019985-&&-translesion synthesis-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0005515-&&-protein binding	G:9606:ISG15			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	ISG15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISG15	0.43220974	0.05373058	154	4	FALSE	ISG15	ISG15	118.1103896	0	154	0	0.78105142	FALSE	0	ISG15	1347876	0.0280045
789854	taxon:9606	2.21143847	9.83E-04	174505	1902	stress induced phosphoprotein 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005515-&&-protein binding	G:9606:STIP1			KEGG-&-1&-hsa05020-&&-Prion diseases	STIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STIP1	0.45219436	0.09744504	154	4	FALSE	STIP1	STIP1	142.3181818	0	154	0	0.79809359	FALSE	0	STIP1	1509808	0.02930502
792845	taxon:9606	2.32046636	0.00136643	181272	1902	erb-b2 receptor tyrosine kinase 3	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0021545-&&-cranial nerve development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0014037-&&-Schwann cell differentiation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0042060-&&-wound healing-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007507-&&-heart development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051048-&&-negative regulation of secretion-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0055025-&&-positive regulation of cardiac muscle tissue development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0038132-&&-neuregulin binding	G:9606:ERBB3	ERBB3	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	ERBB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB3	0.43094785	0.06840362	154	4	FALSE	ERBB3	ERBB3	105.8355263	0	153	0	0.77992227	FALSE	1	ERBB3	1775434	0.02534329
788276	taxon:9606	2.21884355	1.61E-04	177960	1902	ribosomal protein S9	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045903-&&-positive regulation of translational fidelity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS9			KEGG-&-1&-hsa03010-&&-Ribosome	RPS9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS9	0.45068522	0.42079463	153	4	FALSE	RPS9	RPS9	230.3267974	0	153	0	0.79685941	FALSE	0	RPS9	601350	0.04784384
789427	taxon:9606	2.26500709	3.79E-04	175508	1902	matrin 3	gene	biological_process-&-1&-GO:0010608-&&-posttranscriptional regulation of gene expression|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:MATR3				MATR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MATR3	0.44149972	0.17306843	153	4	FALSE	MATR3	MATR3	184.8211921	0	152	0	0.78916549	FALSE	1	MATR3	808258	0.04081448
792066	taxon:9606	2.21679534	0.00108077	182664	1902	complement C1q binding protein	gene	biological_process-&-1&-GO:0039534-&&-negative regulation of MDA-5 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:1901165-&&-positive regulation of trophoblast cell migration-%%-GO:0006915-&&-apoptotic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0008380-&&-RNA splicing-%%-GO:0042256-&&-mature ribosome assembly-%%-GO:2000510-&&-positive regulation of dendritic cell chemotaxis-%%-GO:0006397-&&-mRNA processing-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006955-&&-immune response-%%-GO:0016032-&&-viral process-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0070131-&&-positive regulation of mitochondrial translation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0030984-&&-kininogen binding-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0005540-&&-hyaluronic acid binding-%%-GO:0031690-&&-adrenergic receptor binding-%%-GO:0097177-&&-mitochondrial ribosome binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:C1QBP			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	C1QBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QBP	0.45110163	0.10101545	153	4	FALSE	C1QBP	C1QBP	172.397351	0	152	0	0.79720078	FALSE	1	C1QBP	1650678	0.03570973
787623	taxon:9606	2.32503545	0.00105195	179068	1902	nitric oxide synthase 2	gene	biological_process-&-1&-GO:0032310-&&-prostaglandin secretion-%%-GO:0001912-&&-positive regulation of leukocyte mediated cytotoxicity-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0007623-&&-circadian rhythm-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0072604-&&-interleukin-6 secretion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0072606-&&-interleukin-8 secretion-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043457-&&-regulation of cellular respiration-%%-GO:0018119-&&-peptidyl-cysteine S-nitrosylation-%%-GO:0009617-&&-response to bacterium-%%-GO:0051712-&&-positive regulation of killing of cells of other organism-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006809-&&-nitric oxide biosynthetic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005622-&&-intracellular-%%-GO:0005777-&&-peroxisome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0034618-&&-arginine binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0010181-&&-FMN binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0050661-&&-NADP binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004517-&&-nitric-oxide synthase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0020037-&&-heme binding	G:9606:NOS2	NOS2	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04146-&&-Peroxisome-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05133-&&-Pertussis-%%-hsa04066-&&-HIF-1 signaling pathway	NOS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOS2	0.43010097	0.09753915	152	4	FALSE	NOS2	NOS2	133.3133333	0	151	0	0.77916076	FALSE	1	NOS2	1788394	0.03216803
788044	taxon:9606	2.24326453	2.01E-04	178314	1902	ribosomal protein L3	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008097-&&-5S rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL3			KEGG-&-1&-hsa03010-&&-Ribosome	RPL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL3	0.4457789	0.41495295	152	4	FALSE	RPL3	RPL3	223.8684211	0	152	0	0.79278924	FALSE	0	RPL3	597262	0.0479581
788290	taxon:9606	2.26201355	2.31E-04	177947	1902	ribosomal protein S20	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPS20			KEGG-&-1&-hsa03010-&&-Ribosome	RPS20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS20	0.442084	0.39796096	152	4	FALSE	RPS20	RPS20	213.1776316	0	152	0	0.78966441	FALSE	0	RPS20	617286	0.04694219
790043	taxon:9606	2.22971483	6.63E-04	174024	1902	WD repeat domain 5	gene	biological_process-&-1&-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0031175-&&-neuron projection development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0001501-&&-skeletal system development-%%-GO:0060271-&&-cilium assembly-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036064-&&-ciliary basal body-%%-GO:0071339-&&-MLL1 complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus-%%-GO:0048188-&&-Set1C/COMPASS complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)	G:9606:WDR5			KEGG-&-1&-hsa04934-&&-Cushing syndrome	WDR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR5	0.44848785	0.14961659	152	4	FALSE	WDR5	WDR5	191.3552632	0	152	0	0.79504753	FALSE	0	WDR5	1393826	0.04026836
791238	taxon:9606	2.32314479	3.93E-04	169563	1902	methylphosphate capping enzyme	gene	biological_process-&-1&-GO:0016073-&&-snRNA metabolic process-%%-GO:0040031-&&-snRNA modification-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001510-&&-RNA methylation-%%-GO:0035562-&&-negative regulation of chromatin binding|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008173-&&-RNA methyltransferase activity-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity	G:9606:MEPCE				MEPCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEPCE	0.430451	0.10543743	152	4	FALSE	MEPCE	MEPCE	141.25	0	152	0	0.77947587	FALSE	0	MEPCE	687662	0.03381614
792354	taxon:9606	2.16842603	0.0011062	182175	1902	conserved helix-loop-helix ubiquitous kinase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0009636-&&-response to toxic substance-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0033194-&&-response to hydroperoxide-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0010034-&&-response to acetate-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006954-&&-inflammatory response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0043200-&&-response to amino acid-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008384-&&-IkappaB kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CHUK	CHUK	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CHUK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHUK	0.46116399	0.11642058	152	4	FALSE	CHUK	CHUK	161.06	0	151	0	0.80526233	FALSE	1	CHUK	1683212	0.03136384
788286	taxon:9606	2.26059556	2.09E-04	177949	1902	ribosomal protein S18	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS18			KEGG-&-1&-hsa03010-&&-Ribosome	RPS18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS18	0.4423613	0.41395143	151	4	FALSE	RPS18	RPS18	219.9337748	0	151	0	0.78990074	FALSE	0	RPS18	664458	0.04825225
790479	taxon:9606	2.56325823	9.13E-04	172735	1902	tectonic family member 3	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:TCTN3				TCTN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN3	0.39012847	0.02790287	151	4	FALSE	TCTN3	TCTN3	49.71523179	0	151	0	0.73945696	FALSE	0	TCTN3	1056108	0.0188584
791118	taxon:9606	2.43878998	5.73E-04	169993	1902	leucine rich repeat containing G protein-coupled receptor 4	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045087-&&-innate immune response-%%-GO:0072282-&&-metanephric nephron tubule morphogenesis-%%-GO:0030282-&&-bone mineralization-%%-GO:0061290-&&-canonical Wnt signaling pathway involved in metanephric kidney development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0030539-&&-male genitalia development-%%-GO:0048565-&&-digestive tract development-%%-GO:0001942-&&-hair follicle development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0072202-&&-cell differentiation involved in metanephros development-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:2001013-&&-epithelial cell proliferation involved in renal tubule morphogenesis-%%-GO:0046849-&&-bone remodeling-%%-GO:0007283-&&-spermatogenesis-%%-GO:0072224-&&-metanephric glomerulus development-%%-GO:0036335-&&-intestinal stem cell homeostasis-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0050710-&&-negative regulation of cytokine secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:LGR4			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	LGR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGR4	0.41003941	0.03147107	151	4	FALSE	LGR4	LGR4	90.80536913	0	150	0	0.76020167	FALSE	1	LGR4	800724	0.02648683
787799	taxon:9606	2.34394202	5.66E-04	178771	1902	protein kinase AMP-activated non-catalytic subunit beta 1	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035878-&&-nail development|cellular_component-&-1&-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PRKAB1	PRKAB1	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04921-&&-Oxytocin signaling pathway	PRKAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAB1	0.42663171	0.03337808	150	4	FALSE	PRKAB1	PRKAB1	93.43333333	0	150	0	0.77600966	FALSE	0	PRKAB1	838102	0.02317862
788812	taxon:9606	2.16527493	8.08E-04	176820	1902	ubiquitin B	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0019058-&&-viral life cycle-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1902255-&&-positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1902527-&&-positive regulation of protein monoubiquitination-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0043005-&&-neuron projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UBB			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05012-&&-Parkinson disease-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	UBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBB	0.46183512	0.08912752	150	4	FALSE	UBB	UBB	173.0933333	0	150	0	0.80578751	FALSE	0	UBB	1483144	0.03359871
791828	taxon:9606	2.19851899	4.81E-04	166657	1902	tubulin alpha 1c	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBA1C			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1C	0.45485166	0.14684564	150	4	FALSE	TUBA1C	TUBA1C	191.22	0	150	0	0.80024684	FALSE	0	TUBA1C	1020512	0.03864457
789356	taxon:9606	2.23192059	0.00117185	175676	1902	hepatocyte growth factor-regulated tyrosine kinase substrate	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0072657-&&-protein localization to membrane-%%-GO:0016197-&&-endosomal transport-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0010324-&&-membrane invagination-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0043405-&&-regulation of MAP kinase activity|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0033565-&&-ESCRT-0 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0032585-&&-multivesicular body membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:HGS			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04145-&&-Phagosome	HGS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HGS	0.44804461	0.05441683	149	4	FALSE	HGS	HGS	114.1812081	0	149	0	0.7946799	FALSE	0	HGS	1460654	0.02412901
789698	taxon:9606	2.16023318	3.60E-04	174864	1902	DEAD-box helicase 17	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008186-&&-RNA-dependent ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX17				DDX17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX17	0.46291299	0.18236884	149	4	FALSE	DDX17	DDX17	239.462585	0	148	0	0.8066278	FALSE	1	DDX17	1040128	0.04613923
791744	taxon:9606	2.23664723	8.84E-04	167087	1902	itchy E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006915-&&-apoptotic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0002669-&&-positive regulation of T cell anergy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046642-&&-negative regulation of alpha-beta T cell proliferation-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0090085-&&-regulation of protein deubiquitination-%%-GO:0051607-&&-defense response to virus-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035519-&&-protein K29-linked ubiquitination-%%-GO:0006954-&&-inflammatory response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0045236-&&-CXCR chemokine receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043021-&&-ribonucleoprotein complex binding	G:9606:ITCH			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	ITCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITCH	0.44709777	0.0751095	149	4	FALSE	ITCH	ITCH	128.2040816	0	148	0	0.79389213	FALSE	1	ITCH	1309788	0.02721522
792217	taxon:9606	2.2869072	9.71E-04	182396	1902	ATM serine/threonine kinase	gene	biological_process-&-1&-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007507-&&-heart development-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0090399-&&-replicative senescence-%%-GO:0000732-&&-strand displacement-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0071500-&&-cellular response to nitrosative stress-%%-GO:1904884-&&-positive regulation of telomerase catalytic core complex assembly-%%-GO:0002331-&&-pre-B cell allelic exclusion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0007140-&&-male meiosis-%%-GO:1904262-&&-negative regulation of TORC1 signaling-%%-GO:0001541-&&-ovarian follicle development-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0048538-&&-thymus development-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0051972-&&-regulation of telomerase activity-%%-GO:0097694-&&-establishment of RNA localization to telomere-%%-GO:0097695-&&-establishment of macromolecular complex localization to telomere-%%-GO:0048599-&&-oocyte development-%%-GO:0007143-&&-female meiotic division-%%-GO:0001756-&&-somitogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0009791-&&-post-embryonic development-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0042159-&&-lipoprotein catabolic process-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:1904358-&&-positive regulation of telomere maintenance via telomere lengthening-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006260-&&-DNA replication-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0072434-&&-signal transduction involved in mitotic G2 DNA damage checkpoint-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005819-&&-spindle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990391-&&-DNA repair complex|molecular_function-&-1&-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004677-&&-DNA-dependent protein kinase activity	G:9606:ATM	ATM	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03440-&&-Homologous recombination-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance	ATM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATM	0.43727179	0.08042121	149	4	FALSE	ATM	ATM	123.5782313	0	148	0	0.78551547	FALSE	1	ATM	1280714	0.02816807
792700	taxon:9606	2.25996534	3.31E-04	181541	1902	DEAH-box helicase 15	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0043279-&&-response to alkaloid-%%-GO:0006397-&&-mRNA processing-%%-GO:0009636-&&-response to toxic substance|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0071008-&&-U2-type post-mRNA release spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding	G:9606:DHX15			KEGG-&-1&-hsa03040-&&-Spliceosome	DHX15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX15	0.44248466	0.18746599	149	4	FALSE	DHX15	DHX15	204.1879195	0	149	0	0.79000578	FALSE	0	DHX15	770464	0.04475842
793203	taxon:9606	2.24925161	6.16E-04	180535	1902	protein arginine methyltransferase 1	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0046985-&&-positive regulation of hemoglobin biosynthetic process-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031175-&&-neuron projection development-%%-GO:0043985-&&-histone H4-R3 methylation-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0016571-&&-histone methylation-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0008170-&&-N-methyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008276-&&-protein methyltransferase activity	G:9606:PRMT1			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	PRMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT1	0.44459232	0.13763862	149	4	FALSE	PRMT1	PRMT1	200.3129252	0	148	0	0.7917914	FALSE	1	PRMT1	1285652	0.04328336
793248	taxon:9606	2.46856783	6.13E-04	180454	1902	mitochondrial ribosomal protein L58	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016150-&&-translation release factor activity, codon nonspecific-%%-GO:0004045-&&-aminoacyl-tRNA hydrolase activity	G:9606:MRPL58				MRPL58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL58	0.40509318	0.05931435	149	4	FALSE	MRPL58	MRPL58	78.90604027	0	149	0	0.7552387	FALSE	0	MRPL58	750388	0.02433507
788074	taxon:9606	2.28265322	2.77E-04	178282	1902	ribosomal protein L31	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL31			KEGG-&-1&-hsa03010-&&-Ribosome	RPL31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL31	0.43808669	0.44447509	148	4	FALSE	RPL31	RPL31	219.5135135	0	148	0	0.78622446	FALSE	0	RPL31	656960	0.0496734
789114	taxon:9606	2.36442414	9.76E-04	176169	1902	HECT and RLD domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032183-&&-SUMO binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:HERC2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HERC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC2	0.42293596	0.03845064	148	4	FALSE	HERC2	HERC2	89.69863014	0	147	0	0.77259598	FALSE	1	HERC2	1118756	0.0229792
789381	taxon:9606	2.28359855	0.00131211	175622	1902	VAMP associated protein A	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0008219-&&-cell death-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090114-&&-COPII-coated vesicle budding-%%-GO:0031175-&&-neuron projection development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0044791-&&-positive regulation by host of viral release from host cell-%%-GO:0070972-&&-protein localization to endoplasmic reticulum-%%-GO:0061025-&&-membrane fusion|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0033149-&&-FFAT motif binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:VAPA			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	VAPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAPA	0.43790534	0.0739726	148	4	FALSE	VAPA	VAPA	113.630137	0	147	0	0.78606691	FALSE	1	VAPA	1554350	0.02580241
789614	taxon:9606	2.25980778	7.69E-04	175052	1902	ring-box 1	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0045116-&&-protein neddylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006513-&&-protein monoubiquitination|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex-%%-GO:0030891-&&-VCB complex-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0019788-&&-NEDD8 transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding	G:9606:RBX1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04350-&&-TGF-beta signaling pathway	RBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBX1	0.44251551	0.1005196	148	4	FALSE	RBX1	RBX1	148.1232877	0	147	0	0.79003204	FALSE	1	RBX1	1241934	0.0324461
790804	taxon:9606	2.32078147	8.74E-04	171159	1902	SH3 domain containing kinase binding protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043005-&&-neuron projection-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:SH3KBP1			KEGG-&-1&-hsa04144-&&-Endocytosis	SH3KBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3KBP1	0.43088934	0.06273028	148	4	FALSE	SH3KBP1	SH3KBP1	104.6232877	0	147	0	0.77986975	FALSE	1	SH3KBP1	1132596	0.02508786
788058	taxon:9606	2.32046636	5.54E-05	178296	1902	ribosomal protein L19	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0070180-&&-large ribosomal subunit rRNA binding-%%-GO:1990932-&&-5.8S rRNA binding	G:9606:RPL19			KEGG-&-1&-hsa03010-&&-Ribosome	RPL19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL19	0.43094785	0.47796105	147	4	FALSE	RPL19	RPL19	232.6462585	0	147	0	0.77992227	FALSE	0	RPL19	308186	0.05547121
793210	taxon:9606	2.21254136	6.62E-04	180520	1902	DnaJ heat shock protein family (Hsp40) member A1	gene	biological_process-&-1&-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0051223-&&-regulation of protein transport-%%-GO:1901998-&&-toxin transport-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0006457-&&-protein folding-%%-GO:1905259-&&-negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0009408-&&-response to heat|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0098554-&&-cytoplasmic side of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005524-&&-ATP binding	G:9606:DNAJA1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA1	0.45196895	0.11201193	147	4	FALSE	DNAJA1	DNAJA1	188.8231293	0	147	0	0.79790977	FALSE	0	DNAJA1	1312414	0.03880179
793358	taxon:9606	2.2040334	5.16E-04	180240	1902	heterogeneous nuclear ribonucleoprotein C (C1/C2)	gene	biological_process-&-1&-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0008380-&&-RNA splicing-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:HNRNPC			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPC	0.45371363	0.16503831	147	4	FALSE	HNRNPC	HNRNPC	225	0	146	0	0.79932777	FALSE	1	HNRNPC	1130376	0.0457475
787893	taxon:9606	2.26989129	7.78E-04	178651	1902	proteasome 26S subunit, ATPase 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001824-&&-blastocyst development-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0000932-&&-P-body-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:PSMC3			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC3	0.44054973	0.15112665	146	4	FALSE	PSMC3	PSMC3	137.9166667	0	145	0	0.78835145	FALSE	1	PSMC3	1168092	0.03058914
788054	taxon:9606	2.31652749	1.27E-04	178300	1902	ribosomal protein L15	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045471-&&-response to ethanol-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031672-&&-A band-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL15			KEGG-&-1&-hsa03010-&&-Ribosome	RPL15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL15	0.43168061	0.47557865	146	4	FALSE	RPL15	RPL15	217.3287671	0	146	0	0.78057875	FALSE	0	RPL15	426964	0.05164657
792526	taxon:9606	2.27556326	0.00179923	181849	1902	calnexin	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0009306-&&-protein secretion-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0007568-&&-aging-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0072583-&&-clathrin-dependent endocytosis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0043197-&&-dendritic spine-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0030424-&&-axon-%%-GO:0005840-&&-ribosome-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CANX			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CANX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CANX	0.43945164	0.09418989	146	4	FALSE	CANX	CANX	147.7671233	0	146	0	0.78740612	FALSE	0	CANX	2295324	0.03312678
788048	taxon:9606	2.31069797	1.76E-04	178305	1902	ribosomal protein L9	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005840-&&-ribosome|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding	G:9606:RPL9			KEGG-&-1&-hsa03010-&&-Ribosome	RPL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL9	0.43276967	0.46149425	145	4	FALSE	RPL9	RPL9	217.9034483	0	145	0	0.78155034	FALSE	0	RPL9	493962	0.05134948
788540	taxon:9606	2.24090121	7.25E-04	177474	1902	spectrin alpha, non-erythrocytic 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007411-&&-axon guidance-%%-GO:0051693-&&-actin filament capping-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0035580-&&-specific granule lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0008091-&&-spectrin-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:SPTAN1			KEGG-&-1&-hsa04210-&&-Apoptosis	SPTAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTAN1	0.44624903	0.11197318	145	4	FALSE	SPTAN1	SPTAN1	190.0068966	0	145	0	0.79318313	FALSE	0	SPTAN1	1338604	0.04047005
788902	taxon:9606	2.31904837	5.94E-04	176644	1902	splicing factor 1	gene	biological_process-&-1&-GO:0033327-&&-Leydig cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0030575-&&-nuclear body organization-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0030238-&&-male sex determination-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050810-&&-regulation of steroid biosynthetic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0045131-&&-pre-mRNA branch point binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SF1				SF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF1	0.43121136	0.10203881	145	4	FALSE	SF1	SF1	149.2027972	0	144	0	0.78015861	FALSE	1	SF1	1002778	0.03557044
793309	taxon:9606	2.47487002	2.12E-04	163949	1902	ring finger and CCCH-type domains 1	gene	biological_process-&-1&-GO:0050856-&&-regulation of T cell receptor signaling pathway-%%-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0048535-&&-lymph node development-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0045623-&&-negative regulation of T-helper cell differentiation-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0048536-&&-spleen development-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0061470-&&-T follicular helper cell differentiation-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0002635-&&-negative regulation of germinal center formation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0001782-&&-B cell homeostasis|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:RC3H1				RC3H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RC3H1	0.40406162	0.10210728	145	4	FALSE	RC3H1	RC3H1	117.062069	0	145	0	0.75418833	FALSE	0	RC3H1	409246	0.03634883
788424	taxon:9606	2.20639672	3.21E-04	177692	1902	serine and arginine rich splicing factor 1	gene	biological_process-&-1&-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0097421-&&-liver regeneration-%%-GO:0000395-&&-mRNA 5'-splice site recognition-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0050733-&&-RS domain binding	G:9606:SRSF1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa03040-&&-Spliceosome	SRSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF1	0.45322765	0.22065728	144	4	FALSE	SRSF1	SRSF1	216.6549296	0	143	0	0.79893388	FALSE	1	SRSF1	835216	0.04419725
789876	taxon:9606	2.32991965	2.84E-04	174462	1902	splicing factor 3a subunit 1	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005686-&&-U2 snRNP-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A1			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A1	0.42919935	0.19706682	144	4	FALSE	SF3A1	SF3A1	190.6944444	0	144	0	0.77834673	FALSE	0	SF3A1	678404	0.04611548
791636	taxon:9606	2.39688042	5.72E-04	167709	1902	Nanog homeobox	gene	biological_process-&-1&-GO:0001714-&&-endodermal cell fate specification-%%-GO:0030154-&&-cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:NANOG			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	NANOG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NANOG	0.41720897	0.03785836	144	4	FALSE	NANOG	NANOG	94.95774648	0	143	0	0.7671866	FALSE	1	NANOG	932062	0.02562186
792232	taxon:9606	2.18496928	6.69E-04	182372	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	gene	biological_process-&-1&-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0009790-&&-embryo development-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0045261-&&-proton-transporting ATP synthase complex, catalytic core F(1)-%%-GO:0016020-&&-membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:ATP5A1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5A1	0.45767234	0.14224353	144	4	FALSE	ATP5A1	ATP5A1	207.9929578	0	143	0	0.80250512	FALSE	1	ATP5A1	1335050	0.04126026
792363	taxon:9606	2.26847329	6.85E-04	182159	1902	adaptor related protein complex 2 mu 1 subunit	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030122-&&-AP-2 adaptor complex|molecular_function-&-1&-GO:0005048-&&-signal sequence binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0044325-&&-ion channel binding	G:9606:AP2M1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2M1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2M1	0.44082511	0.1000899	144	4	FALSE	AP2M1	AP2M1	137.1690141	0	143	0	0.78858778	FALSE	1	AP2M1	1035504	0.03044086
792822	taxon:9606	2.22057665	0.00125789	181311	1902	enolase 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009615-&&-response to virus-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000015-&&-phosphopyruvate hydratase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004634-&&-phosphopyruvate hydratase activity	G:9606:ENO1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa03018-&&-RNA degradation	ENO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENO1	0.45033348	0.12121212	144	4	FALSE	ENO1	ENO1	179.9791667	0	144	0	0.79657056	FALSE	0	ENO1	1822152	0.03744596
793014	taxon:9606	2.35969749	9.10E-04	180892	1902	G protein-coupled receptor kinase 5	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0007217-&&-tachykinin receptor signaling pathway-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:GRK5			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway	GRK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK5	0.42378313	0.04934572	144	4	FALSE	GRK5	GRK5	109.3309859	0	143	0	0.77338375	FALSE	1	GRK5	1140750	0.02776972
787184	taxon:9606	2.26563731	0.00135723	179911	1902	SMAD family member 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030902-&&-hindbrain development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060348-&&-bone development-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0051216-&&-cartilage development-%%-GO:0030901-&&-midbrain development-%%-GO:0006954-&&-inflammatory response-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042592-&&-homeostatic process-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0031053-&&-primary miRNA processing-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0002051-&&-osteoblast fate commitment-%%-GO:0001710-&&-mesodermal cell fate commitment-%%-GO:0007276-&&-gamete generation-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005622-&&-intracellular-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0070878-&&-primary miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0070410-&&-co-SMAD binding	G:9606:SMAD1	SMAD1	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD1	0.44137691	0.07477204	143	4	FALSE	SMAD1	SMAD1	113.822695	0	142	0	0.78906045	FALSE	1	SMAD1	1537974	0.02508453
788056	taxon:9606	2.25129983	1.86E-04	178302	1902	ribosomal protein L12	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding	G:9606:RPL12			KEGG-&-1&-hsa03010-&&-Ribosome	RPL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL12	0.44418784	0.45237861	143	4	FALSE	RPL12	RPL12	218.5384615	0	143	0	0.79145003	FALSE	0	RPL12	525332	0.04728072
788079	taxon:9606	2.33275563	2.19E-04	178275	1902	ribosomal protein L37a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RPL37A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL37A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL37A	0.42867756	0.40736728	143	4	FALSE	RPL37A	RPL37A	194.006993	0	143	0	0.77787406	FALSE	0	RPL37A	496984	0.04716242
788720	taxon:9606	2.20151253	0.00117383	177121	1902	heat shock protein 90 beta family member 1	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0031247-&&-actin rod assembly-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0015031-&&-protein transport-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0051208-&&-sequestering of calcium ion-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0002224-&&-toll-like receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0046790-&&-virion binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:HSP90B1	HSP90B1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSP90B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90B1	0.45423316	0.10233029	143	4	FALSE	HSP90B1	HSP90B1	181.7234043	0	142	0	0.79974791	FALSE	1	HSP90B1	1774656	0.03685354
788801	taxon:9606	2.27839924	5.93E-04	176846	1902	Tu translation elongation factor, mitochondrial	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding	G:9606:TUFM				TUFM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUFM	0.43890464	0.16517286	143	4	FALSE	TUFM	TUFM	191.2167832	0	143	0	0.78693346	FALSE	0	TUFM	1057964	0.04297343
791158	taxon:9606	2.29415472	6.55E-04	169863	1902	pre-mRNA processing factor 40 homolog A	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF40A			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF40A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF40A	0.43589039	0.13991895	143	4	FALSE	PRPF40A	PRPF40A	162.5390071	0	142	0	0.78430755	FALSE	1	PRPF40A	1000224	0.03735551
792398	taxon:9606	2.31936348	4.47E-04	182092	1902	cryptochrome circadian clock 2	gene	biological_process-&-1&-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:2000118-&&-regulation of sodium-dependent phosphate transport-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0000719-&&-photoreactive repair-%%-GO:0007623-&&-circadian rhythm-%%-GO:0009785-&&-blue light signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003914-&&-DNA (6-4) photolyase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0071949-&&-FAD binding-%%-GO:0003904-&&-deoxyribodipyrimidine photo-lyase activity-%%-GO:0009882-&&-blue light photoreceptor activity	G:9606:CRY2			KEGG-&-1&-hsa04710-&&-Circadian rhythm	CRY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRY2	0.43115277	0.08399189	143	4	FALSE	CRY2	CRY2	142.4184397	0	142	0	0.78010609	FALSE	1	CRY2	806032	0.03391348
793363	taxon:9606	2.20623917	4.96E-04	180238	1902	heterogeneous nuclear ribonucleoprotein F	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPF				HNRNPF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPF	0.45326002	0.17295381	143	4	FALSE	HNRNPF	HNRNPF	220.3006993	0	143	0	0.79896014	FALSE	0	HNRNPF	1119250	0.04488319
787582	taxon:9606	2.25240271	2.30E-04	179147	1902	ribosomal protein L10a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045471-&&-response to ethanol-%%-GO:0006412-&&-translation-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL10A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10A	0.44397034	0.47907302	142	4	FALSE	RPL10A	RPL10A	233.084507	0	142	0	0.79126622	FALSE	0	RPL10A	518852	0.05043875
787625	taxon:9606	2.24468253	5.08E-04	179070	1902	non-POU domain containing, octamer-binding	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0007623-&&-circadian rhythm-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0042382-&&-paraspeckles-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding	G:9606:NONO				NONO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NONO	0.4454973	0.12055498	142	4	FALSE	NONO	NONO	197.0571429	0	141	0	0.79255291	FALSE	1	NONO	1040254	0.04221294
788100	taxon:9606	2.1824484	0.00104229	178243	1902	prohibitin	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0016575-&&-histone deacetylation-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:0045917-&&-positive regulation of complement activation-%%-GO:0050821-&&-protein stabilization-%%-GO:0007165-&&-signal transduction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0001850-&&-complement component C3a binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001851-&&-complement component C3b binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031871-&&-proteinase activated receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:PHB				PHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHB	0.45820098	0.11752786	141	4	FALSE	PHB	PHB	190.106383	0	141	0	0.80292527	FALSE	0	PHB	1607348	0.03762571
788261	taxon:9606	2.23995588	6.37E-04	177977	1902	ribophorin I	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0005515-&&-protein binding	G:9606:RPN1			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPN1	0.44643736	0.14042553	141	4	FALSE	RPN1	RPN1	174.4893617	0	141	0	0.79334069	FALSE	0	RPN1	1215506	0.037154
788294	taxon:9606	2.34346936	1.04E-04	177942	1902	ribosomal protein S24	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0015935-&&-small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS24			KEGG-&-1&-hsa03010-&&-Ribosome	RPS24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS24	0.42671776	0.45055724	141	4	FALSE	RPS24	RPS24	199.893617	0	141	0	0.77608844	FALSE	0	RPS24	323510	0.04920889
788607	taxon:9606	2.20450607	4.96E-04	177348	1902	t-complex 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007021-&&-tubulin complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0044053-&&-translocation of peptides or proteins into host cell cytoplasm-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:2000109-&&-regulation of macrophage apoptotic process-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005829-&&-cytosol-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TCP1				TCP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCP1	0.45361635	0.15481256	141	4	FALSE	TCP1	TCP1	198.0780142	0	141	0	0.79924899	FALSE	0	TCP1	1206360	0.04027613
792579	taxon:9606	2.23948322	5.57E-04	181781	1902	chaperonin containing TCP1 subunit 6A	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0071987-&&-WD40-repeat domain binding	G:9606:CCT6A				CCT6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT6A	0.44653159	0.15714286	141	4	FALSE	CCT6A	CCT6A	187.248227	0	141	0	0.79341946	FALSE	0	CCT6A	1218410	0.03981162
788064	taxon:9606	2.30927997	1.33E-04	178295	1902	ribosomal protein L21	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL21			KEGG-&-1&-hsa03010-&&-Ribosome	RPL21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL21	0.43303541	0.48591984	140	4	FALSE	RPL21	RPL21	210.9642857	0	140	0	0.78178667	FALSE	0	RPL21	415596	0.04942763
788068	taxon:9606	2.39278399	9.43E-05	178285	1902	ribosomal protein L27a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL27A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL27A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL27A	0.41792322	0.44737924	140	4	FALSE	RPL27A	RPL27A	209.1928571	0	140	0	0.76786933	FALSE	0	RPL27A	342318	0.05582752
788114	taxon:9606	2.28879786	9.90E-04	178213	1902	protein tyrosine phosphatase, non-receptor type 11	gene	biological_process-&-1&-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:0035265-&&-organ growth-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0048839-&&-inner ear development-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0048609-&&-multicellular organismal reproductive process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0031295-&&-T cell costimulation-%%-GO:0060325-&&-face morphogenesis-%%-GO:0030168-&&-platelet activation-%%-GO:0046887-&&-positive regulation of hormone secretion-%%-GO:0007420-&&-brain development-%%-GO:0033277-&&-abortive mitotic cell cycle-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0061582-&&-intestinal epithelial cell migration-%%-GO:0030220-&&-platelet formation-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0048806-&&-genitalia development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0051463-&&-negative regulation of cortisol secretion-%%-GO:0007411-&&-axon guidance-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0060125-&&-negative regulation of growth hormone secretion-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0032528-&&-microvillus organization-%%-GO:0007507-&&-heart development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:PTPN11			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04360-&&-Axon guidance-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	PTPN11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN11	0.43691058	0.10705596	140	4	FALSE	PTPN11	PTPN11	113.1811594	0	139	0	0.78520036	FALSE	1	PTPN11	1289194	0.0258357
788420	taxon:9606	2.20812983	6.70E-04	177700	1902	SET nuclear proto-oncogene	gene	biological_process-&-1&-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0006260-&&-DNA replication-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0016032-&&-viral process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:SET	SET	TRUE		SET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SET	0.45287192	0.1326563	140	4	FALSE	SET	SET	200.7536232	0	139	0	0.79864503	FALSE	1	SET	1296640	0.04101591
790287	taxon:9606	2.43500867	5.83E-04	173417	1902	chromobox 5	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0016605-&&-PML body-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0010369-&&-chromocenter-%%-GO:0005634-&&-nucleus-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005721-&&-pericentric heterochromatin|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:CBX5				CBX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX5	0.41067616	0.16449804	140	4	FALSE	CBX5	CBX5	143.9710145	0	139	0	0.76083189	FALSE	1	CBX5	1039626	0.04133889
792130	taxon:9606	2.23286592	0.00110681	182544	1902	actin, alpha 1, skeletal muscle	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043503-&&-skeletal muscle fiber adaptation-%%-GO:0010226-&&-response to lithium ion-%%-GO:0090131-&&-mesenchyme migration-%%-GO:0009991-&&-response to extracellular stimulus-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0016049-&&-cell growth-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0048741-&&-skeletal muscle fiber development|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0072562-&&-blood microparticle-%%-GO:0030175-&&-filopodium-%%-GO:0005865-&&-striated muscle thin filament-%%-GO:0001725-&&-stress fiber-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0044297-&&-cell body-%%-GO:0030017-&&-sarcomere-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0017022-&&-myosin binding-%%-GO:0043531-&&-ADP binding	G:9606:ACTA1				ACTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTA1	0.44785493	0.07267534	140	4	FALSE	ACTA1	ACTA1	138.7028986	0	139	0	0.79452235	FALSE	1	ACTA1	1398658	0.02924687
792315	taxon:9606	2.22057665	8.50E-04	182240	1902	cofilin 1	gene	biological_process-&-1&-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0014823-&&-response to activity-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0021766-&&-hippocampus development-%%-GO:0010593-&&-negative regulation of lamellipodium assembly-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0097107-&&-postsynaptic density assembly-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:2000784-&&-positive regulation of establishment of cell polarity regulating cell shape-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0030042-&&-actin filament depolymerization-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051511-&&-negative regulation of unidimensional cell growth-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0071362-&&-cellular response to ether-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:1904377-&&-positive regulation of protein localization to cell periphery-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:1902951-&&-negative regulation of dendritic spine maintenance-%%-GO:0030030-&&-cell projection organization-%%-GO:1904783-&&-positive regulation of NMDA glutamate receptor activity-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0009615-&&-response to virus-%%-GO:2000814-&&-positive regulation of barbed-end actin filament capping|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:1902936-&&-phosphatidylinositol bisphosphate binding	G:9606:CFL1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05133-&&-Pertussis	CFL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFL1	0.45033348	0.12230216	140	4	FALSE	CFL1	CFL1	172.2642857	0	140	0	0.79657056	FALSE	0	CFL1	1421468	0.0357662
787809	taxon:9606	2.21931621	0.0013665	178756	1902	protein kinase C delta	gene	biological_process-&-1&-GO:0032079-&&-positive regulation of endodeoxyribonuclease activity-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0032613-&&-interleukin-10 production-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007049-&&-cell cycle-%%-GO:1900163-&&-positive regulation of phospholipid scramblase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0030168-&&-platelet activation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0007165-&&-signal transduction-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0016572-&&-histone phosphorylation-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0023021-&&-termination of signal transduction-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:2000753-&&-positive regulation of glucosylceramide catabolic process-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0090398-&&-cellular senescence-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:2000755-&&-positive regulation of sphingomyelin catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0051490-&&-negative regulation of filopodium assembly-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042119-&&-neutrophil activation-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0032615-&&-interleukin-12 production-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016363-&&-nuclear matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004699-&&-calcium-independent protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0043560-&&-insulin receptor substrate binding	G:9606:PRKCD			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04140-&&-Autophagy - animal-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	PRKCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCD	0.45058924	0.07546157	139	4	FALSE	PRKCD	PRKCD	129.6934307	0	138	0	0.79678063	FALSE	1	PRKCD	1558762	0.02689269
788062	taxon:9606	2.27572081	1.36E-04	178293	1902	ribosomal protein L22	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL22			KEGG-&-1&-hsa03010-&&-Ribosome	RPL22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL22	0.43942121	0.46095298	139	4	FALSE	RPL22	RPL22	224.7625899	0	139	0	0.78737986	FALSE	0	RPL22	467892	0.05020384
788293	taxon:9606	2.33133764	1.24E-04	177943	1902	ribosomal protein S23	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPS23			KEGG-&-1&-hsa03010-&&-Ribosome	RPS23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS23	0.4289383	0.47023251	139	4	FALSE	RPS23	RPS23	193.2805755	0	139	0	0.77811039	FALSE	0	RPS23	383904	0.04683319
788721	taxon:9606	2.35008666	8.80E-04	177120	1902	TNF receptor associated factor 1	gene	biological_process-&-1&-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006461-&&-protein complex assembly-%%-GO:2001236-&&-regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding	G:9606:TRAF1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05222-&&-Small cell lung cancer	TRAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF1	0.42551622	0.06966509	139	4	FALSE	TRAF1	TRAF1	101.2408759	0	138	0	0.77498556	FALSE	1	TRAF1	1130218	0.02532814
788799	taxon:9606	2.19930676	0.00120648	176850	1902	tubulin alpha 4a	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:TUBA4A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA4A	0.45468873	0.11479512	139	4	FALSE	TUBA4A	TUBA4A	185.9208633	0	139	0	0.80011554	FALSE	0	TUBA4A	1678902	0.037563
791495	taxon:9606	2.30077202	8.06E-04	168384	1902	MMS19 homolog, cytosolic iron-sulfur assembly component	gene	biological_process-&-1&-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009725-&&-response to hormone-%%-GO:0000160-&&-phosphorelay signal transduction system-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0007059-&&-chromosome segregation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0016226-&&-iron-sulfur cluster assembly|cellular_component-&-1&-GO:0005675-&&-holo TFIIH complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0071817-&&-MMXD complex-%%-GO:0097361-&&-CIA complex|molecular_function-&-1&-GO:0030331-&&-estrogen receptor binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019899-&&-enzyme binding	G:9606:MMS19				MMS19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMS19	0.43463672	0.05108956	139	4	FALSE	MMS19	MMS19	110.2805755	0	139	0	0.78320466	FALSE	0	MMS19	1045976	0.02553565
787889	taxon:9606	2.28139278	3.53E-04	178652	1902	proteasome 26S subunit, ATPase 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005737-&&-cytoplasm-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC2			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC2	0.43832873	0.2124183	138	4	FALSE	PSMC2	PSMC2	157.7352941	0	137	0	0.78643454	FALSE	1	PSMC2	750404	0.03554502
788706	taxon:9606	2.29825114	3.83E-04	177145	1902	tumor protein p53 binding protein 1	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0002039-&&-p53 binding	G:9606:TP53BP1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	TP53BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53BP1	0.43511346	0.139744	138	4	FALSE	TP53BP1	TP53BP1	177.8550725	0	138	0	0.78362481	FALSE	0	TP53BP1	842762	0.04105109
789548	taxon:9606	2.28879786	7.04E-04	175210	1902	histone deacetylase 4	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0007399-&&-nervous system development-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030183-&&-B cell differentiation-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002076-&&-osteoblast development-%%-GO:0042113-&&-B cell activation-%%-GO:0001501-&&-skeletal system development-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0006954-&&-inflammatory response-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0048742-&&-regulation of skeletal muscle fiber development-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031672-&&-A band-%%-GO:0005634-&&-nucleus-%%-GO:0042641-&&-actomyosin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043234-&&-protein complex-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0001025-&&-RNA polymerase III transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0044212-&&-transcription regulatory region DNA binding	G:9606:HDAC4			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis	HDAC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC4	0.43691058	0.10283224	138	4	FALSE	HDAC4	HDAC4	142.1691177	0	137	0	0.78520036	FALSE	1	HDAC4	1081704	0.03232652
789720	taxon:9606	2.21285647	3.91E-04	174824	1902	chaperonin containing TCP1 subunit 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0090666-&&-scaRNA localization to Cajal body-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0042470-&&-melanosome-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CCT4				CCT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT4	0.45190459	0.16132445	138	4	FALSE	CCT4	CCT4	202.6376812	0	138	0	0.79785726	FALSE	0	CCT4	1117532	0.04161793
792813	taxon:9606	2.2256184	6.11E-04	181324	1902	emerin	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0007517-&&-muscle organ development-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0006936-&&-muscle contraction-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:EMD			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	EMD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EMD	0.44931332	0.09694989	138	4	FALSE	EMD	EMD	180.1985294	0	137	0	0.79573027	FALSE	1	EMD	1193206	0.03758681
787971	taxon:9606	2.37624074	6.52E-04	178480	1902	pericentriolar material 1	gene	biological_process-&-1&-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0001764-&&-neuron migration-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0051297-&&-centrosome organization-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0060271-&&-cilium assembly-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0022027-&&-interkinetic nuclear migration-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0035176-&&-social behavior-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0036064-&&-ciliary basal body-%%-GO:0031965-&&-nuclear membrane-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005813-&&-centrosome-%%-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0000242-&&-pericentriolar material|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding	G:9606:PCM1				PCM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCM1	0.42083278	0.0943538	137	4	FALSE	PCM1	PCM1	102.919708	0	137	0	0.77062654	FALSE	0	PCM1	907232	0.02675766
788788	taxon:9606	2.33448873	8.79E-04	176902	1902	RAB7A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0061724-&&-lipophagy-%%-GO:0048524-&&-positive regulation of viral process-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0022615-&&-protein to membrane docking-%%-GO:0006897-&&-endocytosis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1902583-&&-multi-organism intracellular transport-%%-GO:1905366-&&-negative regulation of intralumenal vesicle formation-%%-GO:1903542-&&-negative regulation of exosomal secretion-%%-GO:0090382-&&-phagosome maturation-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0090385-&&-phagosome-lysosome fusion-%%-GO:0007174-&&-epidermal growth factor catabolic process-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0015031-&&-protein transport-%%-GO:0019076-&&-viral release from host cell-%%-GO:0006622-&&-protein targeting to lysosome|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032419-&&-extrinsic component of lysosome membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0030904-&&-retromer complex-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding-%%-GO:1905394-&&-retromer complex binding-%%-GO:0005525-&&-GTP binding	G:9606:RAB7A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04140-&&-Autophagy - animal-%%-hsa05132-&&-Salmonella infection-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis-%%-hsa04137-&&-Mitophagy - animal	RAB7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB7A	0.42835932	0.07428081	137	4	FALSE	RAB7A	RAB7A	118.0218978	0	137	0	0.77758521	FALSE	0	RAB7A	1184846	0.02878929
788828	taxon:9606	2.21458957	0.00111654	176803	1902	ubiquitin protein ligase E3A	gene	biological_process-&-1&-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0006508-&&-proteolysis-%%-GO:0007420-&&-brain development-%%-GO:0060736-&&-prostate gland growth-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035037-&&-sperm entry-%%-GO:0016032-&&-viral process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000502-&&-proteasome complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:UBE3A			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	UBE3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE3A	0.45155094	0.06633499	137	4	FALSE	UBE3A	UBE3A	137.2888889	0	136	0	0.79756841	FALSE	1	UBE3A	1434066	0.02826438
789574	taxon:9606	2.35733417	7.43E-04	175149	1902	SET domain bifurcated 1	gene	biological_process-&-1&-GO:0045471-&&-response to ethanol-%%-GO:0033273-&&-response to vitamin-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:SETDB1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa00310-&&-Lysine degradation	SETDB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETDB1	0.42420799	0.10079433	137	4	FALSE	SETDB1	SETDB1	142.0145985	0	137	0	0.77377764	FALSE	0	SETDB1	1182268	0.0358638
787614	taxon:9606	2.40680637	2.35E-04	179097	1902	SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0007338-&&-single fertilization-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006364-&&-rRNA processing-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0001651-&&-dense fibrillar component-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0034512-&&-box C/D snoRNA binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0034511-&&-U3 snoRNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0051117-&&-ATPase binding	G:9606:SNU13			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03040-&&-Spliceosome	SNU13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNU13	0.41548835	0.18325665	136	4	FALSE	SNU13	SNU13	155.4253731	0	135	0	0.76553227	FALSE	1	SNU13	479606	0.04249874
788291	taxon:9606	2.2520876	1.19E-04	177941	1902	ribosomal protein S25	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005840-&&-ribosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS25			KEGG-&-1&-hsa03010-&&-Ribosome	RPS25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS25	0.44403246	0.50784314	136	4	FALSE	RPS25	RPS25	229.7205882	0	136	0	0.79131873	FALSE	0	RPS25	421550	0.04972148
789080	taxon:9606	2.37592563	6.88E-04	176228	1902	TSC22 domain family member 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TSC22D1				TSC22D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC22D1	0.42088859	0.0323196	136	4	FALSE	TSC22D1	TSC22D1	92.34328358	0	135	0	0.77067906	FALSE	1	TSC22D1	888280	0.02405033
787226	taxon:9606	2.28501654	3.36E-04	179835	1902	minichromosome maintenance complex component 3	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005658-&&-alpha DNA polymerase:primase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity	G:9606:MCM3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM3	0.43763359	0.16130459	135	4	FALSE	MCM3	MCM3	204.3703704	0	135	0	0.78583058	FALSE	0	MCM3	852324	0.04626737
787919	taxon:9606	2.20939026	0.0011358	178608	1902	protein tyrosine kinase 2	gene	biological_process-&-1&-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0045087-&&-innate immune response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0038007-&&-netrin-activated signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0010594-&&-regulation of endothelial cell migration-%%-GO:0051964-&&-negative regulation of synapse assembly-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0007411-&&-axon guidance-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001890-&&-placenta development-%%-GO:0040023-&&-establishment of nucleus localization-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:1900024-&&-regulation of substrate adhesion-dependent cell spreading-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0021955-&&-central nervous system neuron axonogenesis-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0001570-&&-vasculogenesis-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007172-&&-signal complex assembly-%%-GO:0009790-&&-embryo development-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001764-&&-neuron migration-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0048870-&&-cell motility-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003779-&&-actin binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0008432-&&-JUN kinase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0042169-&&-SH2 domain binding	G:9606:PTK2	PTK2	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer	PTK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTK2	0.45261356	0.10628845	135	4	FALSE	PTK2	PTK2	132.9548872	0	134	0	0.79843496	FALSE	1	PTK2	1391272	0.02720773
788211	taxon:9606	2.32676855	0.00106476	178069	1902	REL proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0034097-&&-response to cytokine-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0006954-&&-inflammatory response-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:REL			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05203-&&-Viral carcinogenesis	REL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REL	0.42978061	0.0414673	135	4	FALSE	REL	REL	99.02255639	0	134	0	0.77887191	FALSE	1	REL	1234554	0.02392295
788590	taxon:9606	2.35150465	6.13E-04	177385	1902	TATA-box binding protein	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0016032-&&-viral process-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001939-&&-female pronucleus-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005672-&&-transcription factor TFIIA complex-%%-GO:0001940-&&-male pronucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001034-&&-RNA polymerase III transcription factor activity, sequence-specific DNA binding	G:9606:TBP			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	TBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBP	0.42525963	0.101162	135	4	FALSE	TBP	TBP	115.3308271	0	134	0	0.77474923	FALSE	1	TBP	865262	0.02868365
789190	taxon:9606	2.35244998	4.40E-04	176034	1902	histone cluster 2 H2B family member e	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2BE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H2BE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2BE	0.42508874	0.21304588	135	4	FALSE	HIST2H2BE	HIST2H2BE	185.2592593	0	135	0	0.77459167	FALSE	0	HIST2H2BE	908826	0.0462764
790167	taxon:9606	2.24153143	2.63E-04	173725	1902	small nuclear ribonucleoprotein U5 subunit 200	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0000354-&&-cis assembly of pre-catalytic spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005682-&&-U5 snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0042802-&&-identical protein binding	G:9606:SNRNP200			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRNP200	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRNP200	0.44612357	0.2028936	135	4	FALSE	SNRNP200	SNRNP200	225.0526316	0	134	0	0.79307809	FALSE	1	SNRNP200	697976	0.04792433
788057	taxon:9606	2.32314479	1.38E-04	178297	1902	ribosomal protein L18a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0097327-&&-response to antineoplastic agent-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL18A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL18A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL18A	0.430451	0.46324767	134	4	FALSE	RPL18A	RPL18A	203.5373134	0	134	0	0.77947587	FALSE	0	RPL18A	362338	0.04853861
788196	taxon:9606	2.37655585	3.64E-04	178096	1902	RB binding protein 7, chromatin remodeling factor	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0048545-&&-response to steroid hormone-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0016575-&&-histone deacetylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity	G:9606:RBBP7				RBBP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP7	0.42077698	0.19279542	134	4	FALSE	RBBP7	RBBP7	166.0447761	0	134	0	0.77057402	FALSE	0	RBBP7	799262	0.04297225
789007	taxon:9606	2.4244525	4.70E-04	176400	1902	gigaxonin	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:GAN				GAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAN	0.41246426	0.07344437	134	4	FALSE	GAN	GAN	123.7424242	0	133	0	0.76259125	FALSE	1	GAN	762616	0.03489038
790605	taxon:9606	2.29620293	0.00211182	171799	1902	ubiquilin 1	gene	biological_process-&-1&-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1901340-&&-negative regulation of store-operated calcium channel activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0035973-&&-aggrephagy-%%-GO:0034140-&&-negative regulation of toll-like receptor 3 signaling pathway-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1902175-&&-regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005829-&&-cytosol-%%-GO:0016235-&&-aggresome-%%-GO:0043234-&&-protein complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBQLN1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UBQLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBQLN1	0.43550158	0.06511682	134	4	FALSE	UBQLN1	UBQLN1	109.5378788	0	133	0	0.78396618	FALSE	1	UBQLN1	2122506	0.02528871
791198	taxon:9606	2.41767764	6.74E-04	169752	1902	ligand dependent nuclear receptor interacting factor 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0005515-&&-protein binding	G:9606:LRIF1				LRIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRIF1	0.41362007	0.05123757	134	4	FALSE	LRIF1	LRIF1	113.5227273	0	133	0	0.76372039	FALSE	1	LRIF1	1058736	0.03157304
788174	taxon:9606	2.28706476	4.87E-04	178125	1902	RAN, member RAS oncogene family	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0021766-&&-hippocampus development-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0071389-&&-cellular response to mineralocorticoid stimulus-%%-GO:0051301-&&-cell division-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0071806-&&-protein transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0035281-&&-pre-miRNA export from nucleus-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0000055-&&-ribosomal large subunit export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:1902570-&&-protein localization to nucleolus-%%-GO:0007286-&&-spermatid development-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0042470-&&-melanosome-%%-GO:0002177-&&-manchette-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0055037-&&-recycling endosome-%%-GO:0000785-&&-chromatin-%%-GO:0030496-&&-midbody-%%-GO:0042565-&&-RNA nuclear export complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005643-&&-nuclear pore-%%-GO:0036126-&&-sperm flagellum-%%-GO:0090543-&&-Flemming body-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0061676-&&-importin-alpha family protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0090631-&&-pre-miRNA transporter activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0019003-&&-GDP binding	G:9606:RAN			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa03013-&&-RNA transport	RAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAN	0.43724166	0.09101585	133	4	FALSE	RAN	RAN	177.0610687	0	132	0	0.78548921	FALSE	1	RAN	962258	0.04022334
788658	taxon:9606	2.3565464	9.95E-04	177243	1902	transforming growth factor beta receptor 1	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060978-&&-angiogenesis involved in coronary vascular morphogenesis-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:1905075-&&-positive regulation of occluding junction disassembly-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0008354-&&-germ cell migration-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043062-&&-extracellular structure organization-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001822-&&-kidney development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0001824-&&-blastocyst development-%%-GO:0008584-&&-male gonad development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0060037-&&-pharyngeal system development-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0009791-&&-post-embryonic development-%%-GO:0042060-&&-wound healing-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0060017-&&-parathyroid gland development-%%-GO:0060043-&&-regulation of cardiac muscle cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048538-&&-thymus development-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0070723-&&-response to cholesterol-%%-GO:0060021-&&-palate development-%%-GO:0003342-&&-proepicardium development-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0001501-&&-skeletal system development-%%-GO:1905223-&&-epicardium morphogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0048870-&&-cell motility-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0007507-&&-heart development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005768-&&-endosome-%%-GO:0043235-&&-receptor complex-%%-GO:0009986-&&-cell surface-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0070022-&&-transforming growth factor beta receptor complex|molecular_function-&-1&-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005025-&&-transforming growth factor beta receptor activity, type I-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0004672-&&-protein kinase activity	G:9606:TGFBR1			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TGFBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBR1	0.4243498	0.0610687	133	4	FALSE	TGFBR1	TGFBR1	93.84732824	0	132	0	0.77390893	FALSE	1	TGFBR1	1082310	0.02369537
788677	taxon:9606	2.29210651	8.36E-04	177212	1902	transketolase	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0005999-&&-xylulose biosynthetic process-%%-GO:0046166-&&-glyceraldehyde-3-phosphate biosynthetic process-%%-GO:0009052-&&-pentose-phosphate shunt, non-oxidative branch-%%-GO:0040008-&&-regulation of growth|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0004802-&&-transketolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0048037-&&-cofactor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TKT	TKT	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00030-&&-Pentose phosphate pathway	TKT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TKT	0.4362799	0.13247211	133	4	FALSE	TKT	TKT	140.610687	0	132	0	0.78464892	FALSE	1	TKT	1178540	0.03206455
789966	taxon:9606	2.27745392	5.97E-04	174221	1902	prohibitin 2	gene	biological_process-&-1&-GO:1902808-&&-positive regulation of cell cycle G1/S phase transition-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050821-&&-protein stabilization-%%-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0033218-&&-amide binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0030331-&&-estrogen receptor binding	G:9606:PHB2				PHB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHB2	0.43908682	0.09273183	133	4	FALSE	PHB2	PHB2	160.7067669	0	133	0	0.78709101	FALSE	0	PHB2	1072090	0.03599725
790322	taxon:9606	2.39656531	0.00106236	173319	1902	protection of telomeres 1	gene	biological_process-&-1&-GO:0016233-&&-telomere capping-%%-GO:1905774-&&-regulation of DNA helicase activity-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0060383-&&-positive regulation of DNA strand elongation-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:1905776-&&-positive regulation of DNA helicase activity-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0032202-&&-telomere assembly|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070187-&&-shelterin complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000783-&&-nuclear telomere cap complex|molecular_function-&-1&-GO:0061821-&&-telomeric D-loop binding-%%-GO:0010521-&&-telomerase inhibitor activity-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:1990955-&&-G-rich single-stranded DNA binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:POT1				POT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POT1	0.41726382	0.04439225	133	4	FALSE	POT1	POT1	92.61832061	0	132	0	0.76723912	FALSE	1	POT1	1198936	0.02498752
792336	taxon:9606	2.30864976	5.38E-04	182211	1902	chromodomain helicase DNA binding protein 3	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0051297-&&-centrosome organization-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007051-&&-spindle organization-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006333-&&-chromatin assembly or disassembly|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016581-&&-NuRD complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004386-&&-helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003723-&&-RNA binding	G:9606:CHD3				CHD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD3	0.43315362	0.11955373	133	4	FALSE	CHD3	CHD3	157.8396947	0	132	0	0.78189171	FALSE	1	CHD3	938610	0.03690758
792632	taxon:9606	2.1890657	5.97E-04	181681	1902	eukaryotic translation elongation factor 1 delta	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding	G:9606:EEF1D			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	EEF1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1D	0.45681589	0.10428655	133	4	FALSE	EEF1D	EEF1D	190.9770992	0	132	0	0.80182238	FALSE	1	EEF1D	1074178	0.03804173
787424	taxon:9606	2.26768552	6.52E-04	179456	1902	lactate dehydrogenase A	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0048569-&&-post-embryonic animal organ development-%%-GO:0006096-&&-glycolytic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007584-&&-response to nutrient-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0051591-&&-response to cAMP-%%-GO:0043627-&&-response to estrogen-%%-GO:0019674-&&-NAD metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006089-&&-lactate metabolic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004459-&&-L-lactate dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0051287-&&-NAD binding	G:9606:LDHA			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	LDHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHA	0.44097825	0.12474657	132	4	FALSE	LDHA	LDHA	172.1923077	0	131	0	0.78871908	FALSE	1	LDHA	1121180	0.03801994
788059	taxon:9606	2.305026	1.15E-04	178299	1902	ribosomal protein L17	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL17			KEGG-&-1&-hsa03010-&&-Ribosome	RPL17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL17	0.43383459	0.47443905	132	4	FALSE	RPL17	RPL17	227.1439394	0	132	0	0.78249567	FALSE	0	RPL17	425522	0.05291031
788080	taxon:9606	2.36206082	1.63E-04	178274	1902	ribosomal protein L38	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0001501-&&-skeletal system development-%%-GO:0006417-&&-regulation of translation-%%-GO:0048318-&&-axial mesoderm development-%%-GO:0034463-&&-90S preribosome assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0001503-&&-ossification-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0033291-&&-eukaryotic 80S initiation complex-%%-GO:0005829-&&-cytosol-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL38			KEGG-&-1&-hsa03010-&&-Ribosome	RPL38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL38	0.42335912	0.37635901	132	4	FALSE	RPL38	RPL38	186.0227273	0	132	0	0.77298986	FALSE	0	RPL38	434976	0.0471421
788944	taxon:9606	2.32976209	2.19E-04	176555	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016584-&&-nucleosome positioning-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic|cellular_component-&-1&-GO:0043596-&&-nuclear replication fork-%%-GO:0001650-&&-fibrillar center-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016589-&&-NURF complex-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0031213-&&-RSF complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0031491-&&-nucleosome binding	G:9606:SMARCA5				SMARCA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA5	0.42922838	0.20655933	132	4	FALSE	SMARCA5	SMARCA5	216.5307692	0	131	0	0.77837298	FALSE	1	SMARCA5	650060	0.05216167
792571	taxon:9606	2.32582322	5.81E-04	181795	1902	cyclin B1	gene	biological_process-&-1&-GO:0042246-&&-tissue regeneration-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0090266-&&-regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0001556-&&-oocyte maturation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0071283-&&-cellular response to iron(III) ion-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0060623-&&-regulation of chromosome condensation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0051987-&&-positive regulation of attachment of spindle microtubules to kinetochore-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:2000775-&&-histone H3-S10 phosphorylation involved in chromosome condensation-%%-GO:0046680-&&-response to DDT-%%-GO:0048565-&&-digestive tract development-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0035173-&&-histone kinase activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005113-&&-patched binding	G:9606:CCNB1	CCNB1	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CCNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNB1	0.42995529	0.0832755	132	4	FALSE	CCNB1	CCNB1	126.1742424	0	132	0	0.77902946	FALSE	0	CCNB1	899516	0.03027939
793213	taxon:9606	2.23617457	6.30E-04	180517	1902	heat shock protein family A (Hsp70) member 1 like	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0044297-&&-cell body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:HSPA1L			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA1L	0.44719228	0.10363174	132	4	FALSE	HSPA1L	HSPA1L	173.3636364	0	132	0	0.7939709	FALSE	0	HSPA1L	1098502	0.03674789
789142	taxon:9606	2.33511895	2.21E-04	176120	1902	mitogen-activated protein kinase kinase kinase 14	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0031295-&&-T cell costimulation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006955-&&-immune response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K14			KEGG-&-1&-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MAP3K14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K14	0.42824371	0.22395833	131	4	FALSE	MAP3K14	MAP3K14	166.6589147	0	130	0	0.77748017	FALSE	1	MAP3K14	467904	0.04052989
789719	taxon:9606	2.20040964	5.28E-04	174825	1902	chaperonin containing TCP1 subunit 7	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005874-&&-microtubule-%%-GO:0005739-&&-mitochondrion-%%-GO:0044297-&&-cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CCT7				CCT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT7	0.45446083	0.1475044	131	4	FALSE	CCT7	CCT7	190.480916	0	131	0	0.79993173	FALSE	0	CCT7	1142888	0.03848568
789889	taxon:9606	2.28281078	2.99E-04	174423	1902	pre-mRNA processing factor 8	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0071356-&&-cellular response to tumor necrosis factor|cellular_component-&-1&-GO:0005682-&&-U5 snRNP-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0017070-&&-U6 snRNA binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0030623-&&-U5 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF8	PRPF8	TRUE	KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF8	0.43805646	0.21729651	131	4	FALSE	PRPF8	PRPF8	203.7674419	0	130	0	0.7861982	FALSE	1	PRPF8	650304	0.04593146
790085	taxon:9606	2.41184812	1.67E-04	173912	1902	ribosomal protein L35	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL35			KEGG-&-1&-hsa03010-&&-Ribosome	RPL35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL35	0.41461981	0.45437463	131	4	FALSE	RPL35	RPL35	204.5114504	0	131	0	0.76469198	FALSE	0	RPL35	396474	0.05635056
791961	taxon:9606	2.23286592	3.50E-04	182806	1902	solute carrier family 25 member 5	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0006810-&&-transport-%%-GO:0015867-&&-ATP transport-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016032-&&-viral process-%%-GO:0015866-&&-ADP transport-%%-GO:1901029-&&-negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0007059-&&-chromosome segregation|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0071817-&&-MMXD complex|molecular_function-&-1&-GO:0015207-&&-adenine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005471-&&-ATP:ADP antiporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:SLC25A5			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SLC25A5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A5	0.44785493	0.21456254	131	4	FALSE	SLC25A5	SLC25A5	220.3587786	0	131	0	0.79452235	FALSE	0	SLC25A5	861678	0.04639948
792397	taxon:9606	2.35638885	3.23E-04	182093	1902	cryptochrome circadian clock 1	gene	biological_process-&-1&-GO:0033762-&&-response to glucagon-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032868-&&-response to insulin-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0009785-&&-blue light signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019915-&&-lipid storage-%%-GO:2000850-&&-negative regulation of glucocorticoid secretion-%%-GO:0006094-&&-gluconeogenesis|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003914-&&-DNA (6-4) photolyase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003904-&&-deoxyribodipyrimidine photo-lyase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0009882-&&-blue light photoreceptor activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:CRY1			KEGG-&-1&-hsa04710-&&-Circadian rhythm	CRY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRY1	0.42437818	0.09035853	131	4	FALSE	CRY1	CRY1	145.503876	0	130	0	0.77393519	FALSE	1	CRY1	620774	0.03654763
792633	taxon:9606	2.21143847	7.13E-04	181680	1902	eukaryotic translation elongation factor 1 gamma	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0009615-&&-response to virus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0045296-&&-cadherin binding	G:9606:EEF1G			KEGG-&-1&-hsa05134-&&-Legionellosis	EEF1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1G	0.45219436	0.10780039	131	4	FALSE	EEF1G	EEF1G	195.372093	0	130	0	0.79809359	FALSE	1	EEF1G	1170850	0.0399634
787386	taxon:9606	2.28848275	4.55E-04	179518	1902	myosin IC	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0051028-&&-mRNA transport-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:1900078-&&-positive regulation of cellular response to insulin stimulus-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:1900748-&&-positive regulation of vascular endothelial growth factor signaling pathway-%%-GO:0006605-&&-protein targeting-%%-GO:0038089-&&-positive regulation of cell migration by vascular endothelial growth factor signaling pathway-%%-GO:0030838-&&-positive regulation of actin filament polymerization|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0060171-&&-stereocilium membrane-%%-GO:0001725-&&-stress fiber-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0031941-&&-filamentous actin-%%-GO:0045160-&&-myosin I complex-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0016461-&&-unconventional myosin complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding	G:9606:MYO1C				MYO1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO1C	0.43697074	0.11568277	130	4	FALSE	MYO1C	MYO1C	142.6076923	0	130	0	0.78525288	FALSE	0	MYO1C	794936	0.03240772
787954	taxon:9606	2.27981724	4.47E-04	178519	1902	p21 (RAC1) activated kinase 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2001271-&&-negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0040008-&&-regulation of growth-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0016032-&&-viral process-%%-GO:0060996-&&-dendritic spine development-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PAK2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	PAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK2	0.43863165	0.08144685	130	4	FALSE	PAK2	PAK2	147.3984375	0	129	0	0.78669713	FALSE	1	PAK2	865588	0.03308824
788303	taxon:9606	2.39467465	8.88E-04	177920	1902	retinoid X receptor alpha	gene	biological_process-&-1&-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0043010-&&-camera-type eye development-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0006766-&&-vitamin metabolic process-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0001893-&&-maternal placenta development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007566-&&-embryo implantation-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0045994-&&-positive regulation of translational initiation by iron-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0004886-&&-9-cis retinoic acid receptor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0044323-&&-retinoic acid-responsive element binding-%%-GO:0019899-&&-enzyme binding	G:9606:RXRA	RXRA	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05160-&&-Hepatitis C-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04976-&&-Bile secretion-%%-hsa05226-&&-Gastric cancer	RXRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RXRA	0.41759326	0.09510335	130	4	FALSE	RXRA	RXRA	100.2265625	0	129	0	0.76755423	FALSE	1	RXRA	1046298	0.02683233
788678	taxon:9606	2.33874271	0.0010445	177215	1902	thymidine kinase 1	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0009157-&&-deoxyribonucleoside monophosphate biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0043097-&&-pyrimidine nucleoside salvage-%%-GO:0046104-&&-thymidine metabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006259-&&-DNA metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019206-&&-nucleoside kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004797-&&-thymidine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TK1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	TK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TK1	0.42758017	0.03297244	130	4	FALSE	TK1	TK1	93.6328125	0	129	0	0.77687621	FALSE	1	TK1	1298382	0.02298608
789647	taxon:9606	2.20592406	3.37E-04	174982	1902	tubulin beta 4B class IVb	gene	biological_process-&-1&-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0007017-&&-microtubule-based process-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003924-&&-GTPase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0005525-&&-GTP binding	G:9606:TUBB4B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB4B	0.45332476	0.15074538	130	4	FALSE	TUBB4B	TUBB4B	234.3692308	0	130	0	0.79901266	FALSE	0	TUBB4B	920744	0.04764571
790078	taxon:9606	2.31400662	2.60E-04	173930	1902	SPT16 homolog, facilitates chromatin remodeling subunit	gene	biological_process-&-1&-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0034724-&&-DNA replication-independent nucleosome organization-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0035101-&&-FACT complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0005515-&&-protein binding	G:9606:SUPT16H				SUPT16H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT16H	0.43215088	0.15538878	130	4	FALSE	SUPT16H	SUPT16H	194.28125	0	129	0	0.7809989	FALSE	1	SUPT16H	681302	0.04572399
790931	taxon:9606	2.28722231	4.67E-04	170679	1902	LUC7 like 2, pre-mRNA splicing factor	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:LUC7L2				LUC7L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUC7L2	0.43721155	0.12561516	130	4	FALSE	LUC7L2	LUC7L2	153.34375	0	129	0	0.78546295	FALSE	1	LUC7L2	773542	0.03475252
792284	taxon:9606	2.22656373	9.69E-04	182285	1902	cyclin dependent kinase 4	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0051301-&&-cell division-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0050994-&&-regulation of lipid catabolic process-%%-GO:0010288-&&-response to lead ion-%%-GO:0046890-&&-regulation of lipid biosynthetic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0060612-&&-adipose tissue development-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0055093-&&-response to hyperoxia-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0010033-&&-response to organic substance-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0045727-&&-positive regulation of translation-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:0042493-&&-response to drug-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0033574-&&-response to testosterone-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000785-&&-chromatin-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097129-&&-cyclin D2-CDK4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0032403-&&-protein complex binding	G:9606:CDK4	CDK4	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma	CDK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK4	0.44912256	0.07608825	130	4	FALSE	CDK4	CDK4	144.8769231	0	130	0	0.79557271	FALSE	0	CDK4	1255416	0.03026455
787876	taxon:9606	2.28627698	3.60E-04	178666	1902	proteasome subunit alpha 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005839-&&-proteasome core complex-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005829-&&-cytosol-%%-GO:0030017-&&-sarcomere-%%-GO:0030016-&&-myofibril-%%-GO:0005844-&&-polysome-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity-%%-GO:0035639-&&-purine ribonucleoside triphosphate binding	G:9606:PSMA6			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA6	0.43739232	0.22553295	129	4	FALSE	PSMA6	PSMA6	169.9457364	0	129	0	0.7856205	FALSE	0	PSMA6	727644	0.03849105
788086	taxon:9606	2.31180085	1.40E-04	178266	1902	ribosomal protein lateral stalk subunit P2	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPLP2			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP2	0.43256321	0.47644044	129	4	FALSE	RPLP2	RPLP2	215.1811024	0	128	0	0.78136652	FALSE	1	RPLP2	383626	0.0505695
788167	taxon:9606	2.32409012	4.63E-04	178139	1902	RAD23 homolog A, nucleotide excision repair protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:RAD23A			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RAD23A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD23A	0.43027591	0.15348081	129	4	FALSE	RAD23A	RAD23A	132.488189	0	128	0	0.77931831	FALSE	1	RAD23A	710980	0.03175274
788357	taxon:9606	2.41878053	0.00110686	177809	1902	syndecan binding protein	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0042327-&&-positive regulation of phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005895-&&-interleukin-5 receptor complex-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016020-&&-membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005912-&&-adherens junction-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005137-&&-interleukin-5 receptor binding-%%-GO:0045545-&&-syndecan binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:SDCBP				SDCBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDCBP	0.41343147	0.03324584	129	4	FALSE	SDCBP	SDCBP	85.68503937	0	128	0	0.76353658	FALSE	1	SDCBP	1242328	0.023955
789296	taxon:9606	2.36852056	6.32E-04	175797	1902	mediator complex subunit 23	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:MED23				MED23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED23	0.42220448	0.09823159	129	4	FALSE	MED23	MED23	100.1860465	0	129	0	0.77191324	FALSE	0	MED23	812244	0.0257448
792268	taxon:9606	2.28281078	6.33E-04	182312	1902	cell division cycle 20	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0090129-&&-positive regulation of synapse maturation-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007049-&&-cell cycle-%%-GO:0050773-&&-regulation of dendrite development-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005819-&&-spindle-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0010997-&&-anaphase-promoting complex binding	G:9606:CDC20			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	CDC20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC20	0.43805646	0.12048494	129	4	FALSE	CDC20	CDC20	144.976378	0	128	0	0.7861982	FALSE	1	CDC20	1023648	0.03265437
788070	taxon:9606	2.39908618	6.80E-05	178287	1902	ribosomal protein L27	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL27			KEGG-&-1&-hsa03010-&&-Ribosome	RPL27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL27	0.41682538	0.5136565	128	4	FALSE	RPL27	RPL27	210.6015625	0	128	0	0.76681897	FALSE	0	RPL27	254244	0.05659601
789927	taxon:9606	2.1991492	3.59E-04	174337	1902	chaperonin containing TCP1 subunit 8	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050821-&&-protein stabilization-%%-GO:0046931-&&-pore complex assembly-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0005576-&&-extracellular region-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005813-&&-centrosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0044297-&&-cell body-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding	G:9606:CCT8				CCT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT8	0.45472131	0.17593504	128	4	FALSE	CCT8	CCT8	216.1640625	0	128	0	0.8001418	FALSE	0	CCT8	985804	0.04352881
790312	taxon:9606	2.36442414	8.19E-05	173348	1902	ribosomal protein L36	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL36			KEGG-&-1&-hsa03010-&&-Ribosome	RPL36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL36	0.42293596	0.47170276	128	4	FALSE	RPL36	RPL36	214.4921875	0	128	0	0.77259598	FALSE	0	RPL36	321084	0.05466162
792846	taxon:9606	2.26910351	4.93E-04	181275	1902	epidermal growth factor receptor pathway substrate 15	gene	biological_process-&-1&-GO:0032456-&&-endocytic recycling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0061024-&&-membrane organization-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0016050-&&-vesicle organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:0015031-&&-protein transport-%%-GO:0019065-&&-receptor-mediated endocytosis of virus by host cell-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0006895-&&-Golgi to endosome transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0060170-&&-ciliary membrane-%%-GO:0016235-&&-aggresome-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0045296-&&-cadherin binding	G:9606:EPS15			KEGG-&-1&-hsa04144-&&-Endocytosis	EPS15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPS15	0.44070268	0.11593651	128	4	FALSE	EPS15	EPS15	165.7777778	0	127	0	0.78848275	FALSE	1	EPS15	952766	0.03664407
787403	taxon:9606	2.23491413	5.94E-04	179491	1902	nucleosome assembly protein 1 like 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006260-&&-DNA replication-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NAP1L1				NAP1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAP1L1	0.44744448	0.13574194	127	4	FALSE	NAP1L1	NAP1L1	202.16	0	126	0	0.79418098	FALSE	1	NAP1L1	1044562	0.04263067
787427	taxon:9606	2.31668505	4.42E-04	179454	1902	lactate dehydrogenase B	gene	biological_process-&-1&-GO:0006089-&&-lactate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0019674-&&-NAD metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0045121-&&-membrane raft-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004459-&&-L-lactate dehydrogenase activity-%%-GO:0019900-&&-kinase binding	G:9606:LDHB			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00640-&&-Propanoate metabolism	LDHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHB	0.43165125	0.12464516	127	4	FALSE	LDHB	LDHB	154.24	0	126	0	0.78055249	FALSE	1	LDHB	805076	0.03647682
788292	taxon:9606	2.32030881	9.62E-05	177940	1902	ribosomal protein S26	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPS26			KEGG-&-1&-hsa03010-&&-Ribosome	RPS26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS26	0.43097712	0.47556555	127	4	FALSE	RPS26	RPS26	208.8346457	0	127	0	0.77994853	FALSE	0	RPS26	363948	0.0496516
788709	taxon:9606	2.29557271	6.68E-04	177143	1902	tumor protein p73	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006298-&&-mismatch repair-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0010165-&&-response to X-ray-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051262-&&-protein tetramerization-%%-GO:0016032-&&-viral process-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0042493-&&-response to drug-%%-GO:0034644-&&-cellular response to UV-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0043508-&&-negative regulation of JUN kinase activity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0000785-&&-chromatin-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding	G:9606:TP73			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04390-&&-Hippo signaling pathway	TP73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP73	0.43562114	0.09032258	127	4	FALSE	TP73	TP73	136.312	0	126	0	0.78407121	FALSE	1	TP73	921664	0.0312749
788861	taxon:9606	2.30927997	5.72E-04	176742	1902	voltage dependent anion channel 1	gene	biological_process-&-1&-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0007612-&&-learning-%%-GO:0006820-&&-anion transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0098656-&&-anion transmembrane transport-%%-GO:1903959-&&-regulation of anion transmembrane transport-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006851-&&-mitochondrial calcium ion transport-%%-GO:0007270-&&-neuron-neuron synaptic transmission-%%-GO:0001662-&&-behavioral fear response-%%-GO:0016032-&&-viral process-%%-GO:1903146-&&-regulation of mitophagy|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005739-&&-mitochondrion-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0015288-&&-porin activity	G:9606:VDAC1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC1	0.43303541	0.1056118	127	4	FALSE	VDAC1	VDAC1	130.7007874	0	127	0	0.78178667	FALSE	0	VDAC1	900530	0.03062158
789608	taxon:9606	2.29068851	2.52E-04	175061	1902	thyroid hormone receptor associated protein 3	gene	biological_process-&-1&-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0008380-&&-RNA splicing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016592-&&-mediator complex-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:THRAP3				THRAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRAP3	0.43654997	0.17035371	127	4	FALSE	THRAP3	THRAP3	201.8503937	0	127	0	0.78488525	FALSE	0	THRAP3	714650	0.04591504
789801	taxon:9606	2.34599023	2.22E-04	174634	1902	serine and arginine repetitive matrix 1	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRRM1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	SRRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRM1	0.42625923	0.16772903	127	4	FALSE	SRRM1	SRRM1	156.7795276	0	127	0	0.77566829	FALSE	0	SRRM1	465494	0.03871099
790412	taxon:9606	2.32030881	9.62E-05	140313	1902	40S ribosomal protein S26	gene		G:9606:LOC101929876				LOC101929876	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC101929876	0.43097712	0.47556555	127	4	FALSE	LOC101929876	LOC101929876	208.8346457	0	127	0	0.77994853	FALSE	0	LOC101929876	363948	0.0496516
792622	taxon:9606	2.30880731	6.67E-04	181701	1902	epithelial cell transforming 2	gene	biological_process-&-1&-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0015031-&&-protein transport-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0000910-&&-cytokinesis-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030496-&&-midbody-%%-GO:0097149-&&-centralspindlin complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017048-&&-Rho GTPase binding	G:9606:ECT2				ECT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECT2	0.43312406	0.03912011	127	4	FALSE	ECT2	ECT2	113.3070866	0	127	0	0.78186545	FALSE	0	ECT2	901466	0.02657018
787490	taxon:9606	2.42697337	4.10E-04	179347	1902	lysine methyltransferase 2A	gene	biological_process-&-1&-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0051899-&&-membrane depolarization-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0048172-&&-regulation of short-term neuronal synaptic plasticity-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0008542-&&-visual learning-%%-GO:0009791-&&-post-embryonic development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:1901674-&&-regulation of histone H3-K27 acetylation-%%-GO:2001040-&&-positive regulation of cellular response to drug-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0035864-&&-response to potassium ion-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0048536-&&-spleen development-%%-GO:0035640-&&-exploration behavior-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0044648-&&-histone H3-K4 dimethylation-%%-GO:0006306-&&-DNA methylation-%%-GO:0071440-&&-regulation of histone H3-K14 acetylation-%%-GO:0032411-&&-positive regulation of transporter activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0071339-&&-MLL1 complex-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0045322-&&-unmethylated CpG binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003680-&&-AT DNA binding	G:9606:KMT2A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa00310-&&-Lysine degradation	KMT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2A	0.41203583	0.17781275	126	4	FALSE	KMT2A	KMT2A	163.5241936	0	125	0	0.7621711	FALSE	1	KMT2A	826242	0.04592244
790147	taxon:9606	2.23286592	2.97E-04	173772	1902	chaperonin containing TCP1 subunit 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0050821-&&-protein stabilization-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere-%%-GO:1901998-&&-toxin transport-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0009615-&&-response to virus-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:1904871-&&-positive regulation of protein localization to Cajal body|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0002199-&&-zona pellucida receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0031681-&&-G-protein beta-subunit binding	G:9606:CCT5				CCT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCT5	0.44785493	0.16266667	126	4	FALSE	CCT5	CCT5	206.3968254	0	126	0	0.79452235	FALSE	0	CCT5	834742	0.04338635
790538	taxon:9606	2.27162439	4.33E-04	172545	1902	pre-mRNA processing factor 19	gene	biological_process-&-1&-GO:0034613-&&-cellular protein localization-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0000349-&&-generation of catalytic spliceosome for first transesterification step-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0072422-&&-signal transduction involved in DNA damage checkpoint|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0071006-&&-U2-type catalytic step 1 spliceosome-%%-GO:0016020-&&-membrane-%%-GO:0035861-&&-site of double-strand break-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PRPF19			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03040-&&-Spliceosome	PRPF19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF19	0.44021362	0.20495673	126	4	FALSE	PRPF19	PRPF19	201.7741936	0	125	0	0.7880626	FALSE	1	PRPF19	715750	0.0447258
792235	taxon:9606	2.23381125	6.91E-04	182369	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	gene	biological_process-&-1&-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0006933-&&-negative regulation of cell adhesion involved in substrate-bound cell migration-%%-GO:0015992-&&-proton transport-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005754-&&-mitochondrial proton-transporting ATP synthase, catalytic core-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005215-&&-transporter activity-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005524-&&-ATP binding	G:9606:ATP5B			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5B	0.4476654	0.12825397	126	4	FALSE	ATP5B	ATP5B	198.7698413	0	126	0	0.79436479	FALSE	0	ATP5B	1204234	0.04189419
787481	taxon:9606	2.37797385	6.82E-04	179352	1902	mutL homolog 1	gene	biological_process-&-1&-GO:0007060-&&-male meiosis chromosome segregation-%%-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0051257-&&-meiotic spindle midzone assembly-%%-GO:0006298-&&-mismatch repair-%%-GO:0043060-&&-meiotic metaphase I plate congression-%%-GO:0045190-&&-isotype switching-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016321-&&-female meiosis chromosome segregation-%%-GO:0048477-&&-oogenesis-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007129-&&-synapsis-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045950-&&-negative regulation of mitotic recombination-%%-GO:0045141-&&-meiotic telomere clustering|cellular_component-&-1&-GO:0005712-&&-chiasma-%%-GO:0005715-&&-late recombination nodule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032389-&&-MutLalpha complex-%%-GO:0005634-&&-nucleus-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0016020-&&-membrane-%%-GO:0000795-&&-synaptonemal complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0032407-&&-MutSalpha complex binding-%%-GO:0032137-&&-guanine/thymine mispair binding	G:9606:MLH1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05213-&&-Endometrial cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer	MLH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLH1	0.42052607	0.05341935	125	4	FALSE	MLH1	MLH1	100.864	0	125	0	0.77033769	FALSE	0	MLH1	830452	0.02620697
787527	taxon:9606	2.28769497	5.64E-04	179256	1902	mutS homolog 2	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006298-&&-mismatch repair-%%-GO:0045190-&&-isotype switching-%%-GO:0006301-&&-postreplication repair-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0007281-&&-germ cell development-%%-GO:0010165-&&-response to X-ray-%%-GO:0010224-&&-response to UV-B-%%-GO:0016447-&&-somatic recombination of immunoglobulin gene segments-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0006281-&&-DNA repair-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0019724-&&-B cell mediated immunity-%%-GO:0008584-&&-male gonad development-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0006302-&&-double-strand break repair|cellular_component-&-1&-GO:0032302-&&-MutSbeta complex-%%-GO:0032301-&&-MutSalpha complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0032143-&&-single thymine insertion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0019237-&&-centromeric DNA binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0032139-&&-dinucleotide insertion or deletion binding-%%-GO:0032137-&&-guanine/thymine mispair binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032181-&&-dinucleotide repeat insertion binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0032142-&&-single guanine insertion binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:MSH2	MSH2	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	MSH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSH2	0.43712121	0.09902706	125	4	FALSE	MSH2	MSH2	152.2276423	0	124	0	0.78538417	FALSE	1	MSH2	891200	0.0344879
788242	taxon:9606	2.39688042	9.01E-04	178016	1902	siah E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007399-&&-nervous system development-%%-GO:0031648-&&-protein destabilization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007411-&&-axon guidance-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:SIAH1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	SIAH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIAH1	0.41720897	0.04544849	125	4	FALSE	SIAH1	SIAH1	110.7886179	0	124	0	0.7671866	FALSE	1	SIAH1	1179292	0.02976292
788296	taxon:9606	2.35213487	1.29E-04	177939	1902	ribosomal protein S27	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008283-&&-cell proliferation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS27			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27	0.42514569	0.42049847	125	4	FALSE	RPS27	RPS27	193.3170732	0	124	0	0.77464419	FALSE	1	RPS27	326776	0.04820266
788381	taxon:9606	2.35575863	2.58E-04	177774	1902	structure specific recognition protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SSRP1				SSRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSRP1	0.42449171	0.19354839	125	4	FALSE	SSRP1	SSRP1	192.968	0	125	0	0.77404023	FALSE	0	SSRP1	632052	0.04841355
788473	taxon:9606	2.29510005	2.75E-04	177579	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SMARCC2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCC2	0.43571085	0.16683871	125	4	FALSE	SMARCC2	SMARCC2	191.256	0	125	0	0.78414999	FALSE	0	SMARCC2	718694	0.0436857
789345	taxon:9606	2.2687884	4.98E-04	175695	1902	structural maintenance of chromosomes 3	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0007165-&&-signal transduction-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0008278-&&-cohesin complex-%%-GO:0005604-&&-basement membrane-%%-GO:0034991-&&-nuclear meiotic cohesin complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030893-&&-meiotic cohesin complex-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0036033-&&-mediator complex binding-%%-GO:0003777-&&-microtubule motor activity	G:9606:SMC3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis	SMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC3	0.44076389	0.12890323	125	4	FALSE	SMC3	SMC3	212.36	0	125	0	0.78853527	FALSE	0	SMC3	1015710	0.04679418
789372	taxon:9606	2.29762092	1.82E-04	175646	1902	DExD-box helicase 21	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX21				DDX21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX21	0.43523281	0.18735484	125	4	FALSE	DDX21	DDX21	232.168	0	125	0	0.78372985	FALSE	0	DDX21	590744	0.05335969
792386	taxon:9606	2.38853001	5.30E-04	182111	1902	cAMP responsive element binding protein 1	gene	biological_process-&-1&-GO:0033762-&&-response to glucagon-%%-GO:0050821-&&-protein stabilization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0007595-&&-lactation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0032916-&&-positive regulation of transforming growth factor beta3 production-%%-GO:0010033-&&-response to organic substance-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0071294-&&-cellular response to zinc ion-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0033363-&&-secretory granule organization-%%-GO:1902065-&&-response to L-glutamate-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008361-&&-regulation of cell size-%%-GO:0034670-&&-chemotaxis to arachidonic acid-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0046887-&&-positive regulation of hormone secretion-%%-GO:0060509-&&-Type I pneumocyte differentiation-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0007165-&&-signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0021983-&&-pituitary gland development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007411-&&-axon guidance-%%-GO:0055025-&&-positive regulation of cardiac muscle tissue development-%%-GO:0007568-&&-aging-%%-GO:0007613-&&-memory-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0008542-&&-visual learning-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0048145-&&-regulation of fibroblast proliferation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060251-&&-regulation of glial cell proliferation-%%-GO:0014823-&&-response to activity-%%-GO:0035094-&&-response to nicotine-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0060430-&&-lung saccule development|cellular_component-&-1&-GO:1990589-&&-ATF4-CREB1 transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1990763-&&-arrestin family protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding	G:9606:CREB1	CREB1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04911-&&-Insulin secretion-%%-hsa04710-&&-Circadian rhythm-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB1	0.41866755	0.11568706	125	4	FALSE	CREB1	CREB1	134.0569106	0	124	0	0.76857833	FALSE	1	CREB1	853148	0.0353856
792438	taxon:9606	2.28942808	6.36E-04	182021	1902	C-terminal binding protein 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090241-&&-negative regulation of histone H4 acetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1903758-&&-negative regulation of transcription from RNA polymerase II promoter by histone modification-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0019079-&&-viral genome replication-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0031065-&&-positive regulation of histone deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0016616-&&-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051287-&&-NAD binding	G:9606:CTBP1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CTBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTBP1	0.43679031	0.08250033	125	4	FALSE	CTBP1	CTBP1	131.5121951	0	124	0	0.78509532	FALSE	1	CTBP1	936114	0.029806
792513	taxon:9606	2.2353868	2.01E-04	181875	1902	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	gene	biological_process-&-1&-GO:0006228-&&-UTP biosynthetic process-%%-GO:0044205-&&-'de novo' UMP biosynthetic process-%%-GO:0007507-&&-heart development-%%-GO:0014075-&&-response to amine-%%-GO:0031000-&&-response to caffeine-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0007595-&&-lactation-%%-GO:0032868-&&-response to insulin-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0019240-&&-citrulline biosynthetic process-%%-GO:0042594-&&-response to starvation-%%-GO:0051414-&&-response to cortisol-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0033574-&&-response to testosterone|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0042995-&&-cell projection-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004070-&&-aspartate carbamoyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004151-&&-dihydroorotase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004088-&&-carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070335-&&-aspartate binding-%%-GO:0019899-&&-enzyme binding	G:9606:CAD			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways	CAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAD	0.44734987	0.16753299	125	4	FALSE	CAD	CAD	208.0162602	0	124	0	0.7941022	FALSE	1	CAD	568922	0.04381886
792740	taxon:9606	2.22924216	4.80E-04	181463	1902	dynein cytoplasmic 1 heavy chain 1	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0034063-&&-stress granule assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0051293-&&-establishment of spindle localization-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005874-&&-microtubule-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008569-&&-ATP-dependent microtubule motor activity, minus-end-directed-%%-GO:0051959-&&-dynein light intermediate chain binding	G:9606:DYNC1H1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome	DYNC1H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC1H1	0.44858294	0.11419355	125	4	FALSE	DYNC1H1	DYNC1H1	204.856	0	125	0	0.79512631	FALSE	0	DYNC1H1	951154	0.04287149
788109	taxon:9606	2.28092012	0.00136466	178220	1902	protein tyrosine phosphatase, non-receptor type 1	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:1990264-&&-peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:1902202-&&-regulation of hepatocyte growth factor receptor signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033157-&&-regulation of intracellular protein transport-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:2000646-&&-positive regulation of receptor catabolic process-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response|cellular_component-&-1&-GO:0098554-&&-cytoplasmic side of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0097443-&&-sorting endosome-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0019899-&&-enzyme binding	G:9606:PTPN1	PTPN1	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04520-&&-Adherens junction	PTPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN1	0.43841956	0.05053516	124	4	FALSE	PTPN1	PTPN1	114.6803279	0	123	0	0.78651331	FALSE	1	PTPN1	1450742	0.0258401
788596	taxon:9606	2.3349614	9.62E-04	177369	1902	transcription factor 4	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0065004-&&-protein-DNA complex assembly-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001093-&&-TFIIB-class transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001011-&&-transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001087-&&-transcription factor activity, TFIIB-class binding	G:9606:TCF4				TCF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF4	0.4282726	0.04470939	124	4	FALSE	TCF4	TCF4	104.204918	0	123	0	0.77750643	FALSE	1	TCF4	1132636	0.02536947
788736	taxon:9606	2.26075311	7.99E-04	177064	1902	tumor susceptibility 101	gene	biological_process-&-1&-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1990182-&&-exosomal secretion-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0046755-&&-viral budding-%%-GO:0016236-&&-macroautophagy-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0019058-&&-viral life cycle-%%-GO:0048524-&&-positive regulation of viral process-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903551-&&-regulation of extracellular exosome assembly-%%-GO:1903772-&&-regulation of viral budding via host ESCRT complex-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0043405-&&-regulation of MAP kinase activity-%%-GO:1903774-&&-positive regulation of viral budding via host ESCRT complex-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:1902186-&&-regulation of viral release from host cell-%%-GO:0016197-&&-endosomal transport-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:2000397-&&-positive regulation of ubiquitin-dependent endocytosis|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000813-&&-ESCRT I complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005771-&&-multivesicular body-%%-GO:0010008-&&-endosome membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046790-&&-virion binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:TSG101			KEGG-&-1&-hsa04144-&&-Endocytosis	TSG101	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSG101	0.44233048	0.0613738	124	4	FALSE	TSG101	TSG101	128.0901639	0	123	0	0.78987448	FALSE	1	TSG101	1000288	0.02798531
789011	taxon:9606	2.46982827	1.25E-04	176384	1902	splicing factor 3a subunit 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005686-&&-U2 snRNP-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A2			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A2	0.40488645	0.21419862	124	4	FALSE	SF3A2	SF3A2	156	0	123	0	0.75502862	FALSE	1	SF3A2	309046	0.04731077
790136	taxon:9606	2.23664723	5.27E-04	173794	1902	microtubule associated protein RP/EB family member 1	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:1904527-&&-negative regulation of microtubule binding-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0008283-&&-cell proliferation-%%-GO:1903033-&&-positive regulation of microtubule plus-end binding|cellular_component-&-1&-GO:0031253-&&-cell projection membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0030981-&&-cortical microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005819-&&-spindle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003723-&&-RNA binding	G:9606:MAPRE1				MAPRE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPRE1	0.44709777	0.10242515	124	4	FALSE	MAPRE1	MAPRE1	158.704918	0	123	0	0.79389213	FALSE	1	MAPRE1	891806	0.0335582
790681	taxon:9606	2.19820388	7.61E-04	171481	1902	TANK binding kinase 1	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0009615-&&-response to virus-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032606-&&-type I interferon production-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0044565-&&-dendritic cell proliferation-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1901214-&&-regulation of neuron death-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045359-&&-positive regulation of interferon-beta biosynthetic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004672-&&-protein kinase activity	G:9606:TBK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	TBK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBK1	0.45491686	0.11895407	124	4	FALSE	TBK1	TBK1	176.7377049	0	123	0	0.80029935	FALSE	1	TBK1	1137044	0.03555045
792179	taxon:9606	2.3332283	5.53E-04	182469	1902	ADP ribosylation factor 6	gene	biological_process-&-1&-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0031529-&&-ruffle organization-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:2000171-&&-negative regulation of dendrite development-%%-GO:0001889-&&-liver development-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0007155-&&-cell adhesion-%%-GO:0036010-&&-protein localization to endosome-%%-GO:0007049-&&-cell cycle-%%-GO:0033028-&&-myeloid cell apoptotic process-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0005768-&&-endosome-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0001726-&&-ruffle-%%-GO:0005938-&&-cell cortex-%%-GO:0043209-&&-myelin sheath-%%-GO:0055038-&&-recycling endosome membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0031996-&&-thioesterase binding	G:9606:ARF6	ARF6	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	ARF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF6	0.42859072	0.05441909	124	4	FALSE	ARF6	ARF6	113.0564516	0	124	0	0.77779528	FALSE	0	ARF6	743992	0.02742718
792374	taxon:9606	2.3614306	4.09E-04	165744	1902	SSX family member 2 interacting protein	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0051297-&&-centrosome organization-%%-GO:0007155-&&-cell adhesion-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:SSX2IP			KEGG-&-1&-hsa04520-&&-Adherens junction	SSX2IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSX2IP	0.42347211	0.08996071	124	4	FALSE	SSX2IP	SSX2IP	104.9180328	0	123	0	0.7730949	FALSE	1	SSX2IP	644922	0.02647487
792706	taxon:9606	2.51378604	7.19E-04	165150	1902	keratin 40	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT40			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT40	0.39780633	0.01403095	124	4	FALSE	KRT40	KRT40	58.2983871	0	124	0	0.74770233	FALSE	0	KRT40	858618	0.01972455
792869	taxon:9606	2.40192217	0.00110739	181250	1902	estrogen receptor 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:1900116-&&-extracellular negative regulation of signal transduction-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0038052-&&-RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0034056-&&-estrogen response element binding-%%-GO:0048019-&&-receptor antagonist activity	G:9606:ESR2	ESR2	TRUE	KEGG-&-1&-hsa01522-&&-Endocrine resistance-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	ESR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESR2	0.41633322	0.07004471	124	4	FALSE	ESR2	ESR2	102.4918033	0	123	0	0.76634631	FALSE	1	ESR2	1458284	0.02772858
787895	taxon:9606	2.34961399	2.71E-04	178644	1902	proteasome 26S subunit, non-ATPase 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD3	PSMD3	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD3	0.42560182	0.21378115	123	4	FALSE	PSMD3	PSMD3	154.9593496	0	123	0	0.77506433	FALSE	0	PSMD3	602498	0.03849114
788183	taxon:9606	2.3318103	4.59E-04	178113	1902	retinoic acid receptor alpha	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0060173-&&-limb development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003417-&&-growth plate cartilage development-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0061037-&&-negative regulation of cartilage development-%%-GO:0030850-&&-prostate gland development-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0060010-&&-Sertoli cell fate commitment-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0060591-&&-chondroblast differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001657-&&-ureteric bud development-%%-GO:0032355-&&-response to estradiol-%%-GO:0001843-&&-neural tube closure-%%-GO:0032736-&&-positive regulation of interleukin-13 production-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0032754-&&-positive regulation of interleukin-5 production-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0034097-&&-response to cytokine-%%-GO:0021766-&&-hippocampus development-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0007281-&&-germ cell development-%%-GO:0031641-&&-regulation of myelination-%%-GO:0045471-&&-response to ethanol-%%-GO:0002068-&&-glandular epithelial cell development-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0060324-&&-face development-%%-GO:0071391-&&-cellular response to estrogen stimulus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000900-&&-translation repressor activity, nucleic acid binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0044323-&&-retinoic acid-responsive element binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0001972-&&-retinoic acid binding-%%-GO:0008144-&&-drug binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:RARA			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	RARA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARA	0.42885135	0.10881543	123	4	FALSE	RARA	RARA	131.6198347	0	122	0	0.77803162	FALSE	1	RARA	753840	0.03177089
788491	taxon:9606	2.35670395	2.35E-04	177553	1902	small nuclear ribonucleoprotein polypeptide A'	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNRPA1			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPA1	0.42432143	0.19938691	123	4	FALSE	SNRPA1	SNRPA1	187.8699187	0	123	0	0.77388267	FALSE	0	SNRPA1	575192	0.04714998
788493	taxon:9606	2.23365369	2.98E-04	177555	1902	small nuclear ribonucleoprotein U1 subunit 70	gene	biological_process-&-1&-GO:0043462-&&-regulation of ATPase activity-%%-GO:0061084-&&-negative regulation of protein refolding-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008380-&&-RNA splicing-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:1904715-&&-negative regulation of chaperone-mediated autophagy|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030619-&&-U1 snRNA binding	G:9606:SNRNP70			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRNP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRNP70	0.44769697	0.21111555	123	4	FALSE	SNRNP70	SNRNP70	240.2845529	0	123	0	0.79439105	FALSE	0	SNRNP70	786328	0.05058622
788870	taxon:9606	2.26343154	6.96E-04	176730	1902	ezrin	gene	biological_process-&-1&-GO:0072697-&&-protein localization to cell cortex-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0046847-&&-filopodium assembly-%%-GO:0030033-&&-microvillus assembly-%%-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0031623-&&-receptor internalization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0043622-&&-cortical microtubule organization-%%-GO:0001951-&&-intestinal D-glucose absorption-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0007411-&&-axon guidance-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0051660-&&-establishment of centrosome localization-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0032532-&&-regulation of microvillus length-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0003376-&&-sphingosine-1-phosphate signaling pathway-%%-GO:0022612-&&-gland morphogenesis-%%-GO:1902896-&&-terminal web assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:0010737-&&-protein kinase A signaling-%%-GO:1900041-&&-negative regulation of interleukin-2 secretion-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0001931-&&-uropod-%%-GO:0044297-&&-cell body-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0001726-&&-ruffle-%%-GO:0030175-&&-filopodium-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0036064-&&-ciliary basal body-%%-GO:0043209-&&-myelin sheath-%%-GO:0001650-&&-fibrillar center-%%-GO:0001772-&&-immunological synapse-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0031528-&&-microvillus membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005903-&&-brush border-%%-GO:0097454-&&-Schwann cell microvillus-%%-GO:0016020-&&-membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005902-&&-microvillus-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0051286-&&-cell tip-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0097449-&&-astrocyte projection-%%-GO:0030315-&&-T-tubule-%%-GO:0031982-&&-vesicle-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0044393-&&-microspike-%%-GO:0036398-&&-TCR signalosome-%%-GO:0098592-&&-cytoplasmic side of apical plasma membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0051117-&&-ATPase binding	G:9606:EZR			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	EZR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EZR	0.44180704	0.1	123	4	FALSE	EZR	EZR	154.338843	0	122	0	0.78942808	FALSE	1	EZR	1027352	0.03385366
789025	taxon:9606	2.24972428	4.18E-04	176348	1902	ubiquitin specific peptidase 9, X-linked	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0048675-&&-axon extension-%%-GO:0007292-&&-female gamete generation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0001764-&&-neuron migration-%%-GO:0051301-&&-cell division-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070410-&&-co-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP9X				USP9X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP9X	0.44449891	0.09436226	123	4	FALSE	USP9X	USP9X	171.8536585	0	123	0	0.79171262	FALSE	0	USP9X	910356	0.03695428
787422	taxon:9606	2.32472034	6.07E-04	179462	1902	LCK proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030097-&&-hemopoiesis-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051249-&&-regulation of lymphocyte activation-%%-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050862-&&-positive regulation of T cell receptor signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0030217-&&-T cell differentiation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0016477-&&-cell migration-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0042493-&&-response to drug-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0000242-&&-pericentriolar material-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042610-&&-CD8 receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:LCK			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	LCK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCK	0.43015927	0.10938375	122	4	FALSE	LCK	LCK	113.9916667	0	121	0	0.77921328	FALSE	1	LCK	874480	0.02730594
787539	taxon:9606	2.3516622	6.58E-04	179220	1902	protein phosphatase 2 catalytic subunit beta	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0046677-&&-response to antibiotic|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000159-&&-protein phosphatase type 2A complex|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2CB			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04140-&&-Autophagy - animal-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04136-&&-Autophagy - other-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2CB	0.42523114	0.07830917	122	4	FALSE	PPP2CB	PPP2CB	109.8278689	0	122	0	0.77472297	FALSE	0	PPP2CB	883136	0.02734214
789452	taxon:9606	2.26201355	6.19E-04	175436	1902	BCL2 associated athanogene 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0019538-&&-protein metabolic process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:BAG2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	BAG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG2	0.442084	0.09747899	122	4	FALSE	BAG2	BAG2	174.125	0	121	0	0.78966441	FALSE	1	BAG2	1079080	0.03809446
790657	taxon:9606	2.27225461	8.28E-04	138803	1902	LOC400927-CSNK1E readthrough	gene	biological_process-&-1&-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000052-&&-positive regulation of non-canonical Wnt signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034613-&&-cellular protein localization-%%-GO:0007165-&&-signal transduction-%%-GO:0006364-&&-rRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905426-&&-positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048512-&&-circadian behavior-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:LOC400927-CSNK1E			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04710-&&-Circadian rhythm	LOC400927-CSNK1E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC400927-CSNK1E	0.44009153	0.07885154	122	4	FALSE	LOC400927-CSNK1E	LOC400927-CSNK1E	117.0666667	0	121	0	0.78795757	FALSE	1	LOC400927-CSNK1E	1162010	0.02590544
790775	taxon:9606	2.53978257	8.86E-04	171249	1902	transmembrane protein 216	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005929-&&-cilium-%%-GO:0036038-&&-MKS complex	G:9606:TMEM216				TMEM216	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM216	0.39373449	0.01801924	122	4	FALSE	TMEM216	TMEM216	48.25409836	0	122	0	0.74336957	FALSE	0	TMEM216	880742	0.01723406
791576	taxon:9606	2.50386009	3.81E-04	167945	1902	myosin XIX	gene	cellular_component-&-1&-GO:0016459-&&-myosin complex-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0060002-&&-plus-end directed microfilament motor activity-%%-GO:0032027-&&-myosin light chain binding-%%-GO:0016887-&&-ATPase activity	G:9606:MYO19				MYO19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO19	0.39938334	0.11990245	122	4	FALSE	MYO19	MYO19	81.92622951	0	122	0	0.74935665	FALSE	0	MYO19	535434	0.02685374
791966	taxon:9606	2.36946589	0.00105136	182795	1902	annexin A7	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0035176-&&-social behavior-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0009651-&&-response to salt stress-%%-GO:0009992-&&-cellular water homeostasis-%%-GO:0051592-&&-response to calcium ion-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0007599-&&-hemostasis-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042584-&&-chromaffin granule membrane|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:ANXA7				ANXA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA7	0.42203604	0.02506435	122	4	FALSE	ANXA7	ANXA7	91.56557377	0	122	0	0.77175569	FALSE	0	ANXA7	1240908	0.02363484
792418	taxon:9606	2.27225461	8.28E-04	182052	1902	casein kinase 1 epsilon	gene	biological_process-&-1&-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000052-&&-positive regulation of non-canonical Wnt signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034613-&&-cellular protein localization-%%-GO:0007165-&&-signal transduction-%%-GO:0006364-&&-rRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905426-&&-positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048512-&&-circadian behavior-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:CSNK1E			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04710-&&-Circadian rhythm	CSNK1E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1E	0.44009153	0.07885154	122	4	FALSE	CSNK1E	CSNK1E	117.0666667	0	121	0	0.78795757	FALSE	1	CSNK1E	1162010	0.02590544
792824	taxon:9606	2.2869072	5.96E-04	181300	1902	erythrocyte membrane protein band 4.1	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0030054-&&-cell junction-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043234-&&-protein complex-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030507-&&-spectrin binding	G:9606:EPB41				EPB41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41	0.43727179	0.06164476	122	4	FALSE	EPB41	EPB41	127.6885246	0	122	0	0.78551547	FALSE	0	EPB41	840994	0.02891879
793288	taxon:9606	2.44194107	4.28E-04	180374	1902	histone cluster 1 H1 family member a	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1A				HIST1H1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1A	0.40951029	0.11529603	122	4	FALSE	HIST1H1A	HIST1H1A	141.9590164	0	122	0	0.75967649	FALSE	0	HIST1H1A	714810	0.04114284
788071	taxon:9606	2.31321884	9.12E-05	178286	1902	ribosomal protein L30	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:1904571-&&-positive regulation of selenocysteine incorporation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0035368-&&-selenocysteine insertion sequence binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL30			KEGG-&-1&-hsa03010-&&-Ribosome	RPL30	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL30	0.43229805	0.51721763	121	4	FALSE	RPL30	RPL30	214.5123967	0	121	0	0.78113019	FALSE	0	RPL30	318376	0.05037867
788728	taxon:9606	2.40523082	7.08E-04	177103	1902	thyroid hormone receptor interactor 6	gene	biological_process-&-1&-GO:0048041-&&-focal adhesion assembly-%%-GO:0008588-&&-release of cytoplasmic sequestered NF-kappaB-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0045323-&&-interleukin-1 receptor complex|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005149-&&-interleukin-1 receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TRIP6			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	TRIP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP6	0.41576051	0.03076485	121	4	FALSE	TRIP6	TRIP6	82.87394958	0	120	0	0.76579486	FALSE	1	TRIP6	813612	0.02262108
789333	taxon:9606	2.28911297	2.18E-04	175714	1902	poly(A) binding protein cytoplasmic 4	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0006412-&&-translation-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0017130-&&-poly(C) RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PABPC4			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa03018-&&-RNA degradation	PABPC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC4	0.43685044	0.17699725	121	4	FALSE	PABPC4	PABPC4	221.6694215	0	121	0	0.78514784	FALSE	0	PABPC4	578472	0.05022726
791824	taxon:9606	2.36773279	0.0010455	166686	1902	ligand of numb-protein X 1	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:LNX1				LNX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LNX1	0.42234496	0.02036747	121	4	FALSE	LNX1	LNX1	80.35294118	0	120	0	0.77204454	FALSE	1	LNX1	1014662	0.02060088
792611	taxon:9606	2.32030881	6.69E-04	181721	1902	E2F transcription factor 1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071930-&&-negative regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070345-&&-negative regulation of fat cell proliferation-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0030900-&&-forebrain development-%%-GO:1990086-&&-lens fiber cell apoptotic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0043276-&&-anoikis-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0071466-&&-cellular response to xenobiotic stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0035189-&&-Rb-E2F complex-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019901-&&-protein kinase binding	G:9606:E2F1	E2F1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	E2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F1	0.43097712	0.1084022	121	4	FALSE	E2F1	E2F1	137.0165289	0	121	0	0.77994853	FALSE	0	E2F1	892912	0.03255311
787601	taxon:9606	2.37655585	2.17E-04	179113	1902	nuclear factor kappa B subunit 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002467-&&-germinal center formation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045087-&&-innate immune response-%%-GO:0034097-&&-response to cytokine-%%-GO:0002268-&&-follicular dendritic cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0048511-&&-rhythmic process-%%-GO:0007568-&&-aging-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048536-&&-spleen development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033257-&&-Bcl3/NF-kappaB2 complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NFKB2			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05134-&&-Legionellosis	NFKB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKB2	0.42077698	0.15167319	120	4	FALSE	NFKB2	NFKB2	152.9067797	0	119	0	0.77057402	FALSE	1	NFKB2	437556	0.03965794
787902	taxon:9606	2.24499764	3.50E-04	178637	1902	proteasome 26S subunit, non-ATPase 11	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043248-&&-proteasome assembly-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:PSMD11			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD11	0.44543477	0.20672269	120	4	FALSE	PSMD11	PSMD11	174.6333333	0	120	0	0.79250039	FALSE	0	PSMD11	792978	0.03733782
788469	taxon:9606	2.25665669	2.86E-04	177580	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0030850-&&-prostate gland development-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0001741-&&-XY body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SMARCC1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCC1	0.44313342	0.18108069	120	4	FALSE	SMARCC1	SMARCC1	200.1694915	0	119	0	0.79055722	FALSE	1	SMARCC1	729156	0.04335488
788557	taxon:9606	2.44651016	5.46E-04	177446	1902	suppressor of variegation 3-9 homolog 1	gene	biological_process-&-1&-GO:0036124-&&-histone H3-K9 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0006364-&&-rRNA processing-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0036123-&&-histone H3-K9 dimethylation-%%-GO:0048511-&&-rhythmic process-%%-GO:0006325-&&-chromatin organization-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0033553-&&-rDNA heterochromatin-%%-GO:0005652-&&-nuclear lamina-%%-GO:0000794-&&-condensed nuclear chromosome|molecular_function-&-1&-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity	G:9606:SUV39H1			KEGG-&-1&-hsa00310-&&-Lysine degradation	SUV39H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUV39H1	0.40874549	0.12385919	120	4	FALSE	SUV39H1	SUV39H1	129.8135593	0	119	0	0.75891497	FALSE	1	SUV39H1	827068	0.03782067
789240	taxon:9606	2.32393257	8.08E-04	175920	1902	tumor protein p63	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0060529-&&-squamous basal epithelial stem cell differentiation involved in prostate gland acinus development-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0030859-&&-polarized epithelial cell differentiation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0051289-&&-protein homotetramerization-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048807-&&-female genitalia morphogenesis-%%-GO:0060513-&&-prostatic bud formation-%%-GO:0007283-&&-spermatogenesis-%%-GO:2000381-&&-negative regulation of mesoderm development-%%-GO:0010482-&&-regulation of epidermal cell division-%%-GO:0048745-&&-smooth muscle tissue development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045617-&&-negative regulation of keratinocyte differentiation-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0060157-&&-urinary bladder development-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0007499-&&-ectoderm and mesoderm interaction-%%-GO:0001501-&&-skeletal system development-%%-GO:0010165-&&-response to X-ray-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:2000271-&&-positive regulation of fibroblast apoptotic process-%%-GO:0010481-&&-epidermal cell division-%%-GO:0001302-&&-replicative cell aging-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0002064-&&-epithelial cell development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0060197-&&-cloacal septation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:TP63	TP63	TRUE	KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	TP63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP63	0.43030508	0.07243228	120	4	FALSE	TP63	TP63	128.0254237	0	119	0	0.77934457	FALSE	1	TP63	932884	0.03060658
789416	taxon:9606	2.28643454	2.20E-04	175530	1902	elongation factor Tu GTP binding domain containing 2	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0035690-&&-cellular response to drug-%%-GO:0006397-&&-mRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:EFTUD2			KEGG-&-1&-hsa03040-&&-Spliceosome	EFTUD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFTUD2	0.43736218	0.21338548	120	4	FALSE	EFTUD2	EFTUD2	213.5762712	0	119	0	0.78559424	FALSE	1	EFTUD2	532628	0.04820943
789480	taxon:9606	2.37450764	3.23E-04	175374	1902	nuclear receptor corepressor 2	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0072365-&&-regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005112-&&-Notch binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:NCOR2			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection	NCOR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOR2	0.42113994	0.14985994	120	4	FALSE	NCOR2	NCOR2	148.6083333	0	120	0	0.77091539	FALSE	0	NCOR2	659768	0.03833849
789784	taxon:9606	2.34173625	5.23E-04	174686	1902	proteasome activator subunit 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0008537-&&-proteasome activator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0097371-&&-MDM2/MDM4 family protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0061133-&&-endopeptidase activator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0002039-&&-p53 binding	G:9606:PSME3			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05160-&&-Hepatitis C	PSME3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSME3	0.42703357	0.09459655	120	4	FALSE	PSME3	PSME3	133.3050848	0	119	0	0.77637729	FALSE	1	PSME3	774490	0.03272215
791962	taxon:9606	2.18654482	4.91E-04	182803	1902	annexin A2	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0007589-&&-body fluid secretion-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0032804-&&-negative regulation of low-density lipoprotein particle receptor catabolic process-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0001525-&&-angiogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:1905581-&&-positive regulation of low-density lipoprotein particle clearance-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0036035-&&-osteoclast development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0097066-&&-response to thyroid hormone-%%-GO:1905599-&&-positive regulation of low-density lipoprotein receptor activity-%%-GO:1905602-&&-positive regulation of receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0001765-&&-membrane raft assembly-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0042730-&&-fibrinolysis-%%-GO:1905597-&&-positive regulation of low-density lipoprotein particle receptor binding-%%-GO:0006900-&&-membrane budding|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031902-&&-late endosome membrane-%%-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0044354-&&-macropinosome-%%-GO:0042470-&&-melanosome-%%-GO:0005604-&&-basement membrane-%%-GO:0030496-&&-midbody-%%-GO:0031012-&&-extracellular matrix-%%-GO:1990667-&&-PCSK9-AnxA2 complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005768-&&-endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0035749-&&-myelin sheath adaxonal region-%%-GO:0001726-&&-ruffle-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0019897-&&-extrinsic component of plasma membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0019834-&&-phospholipase A2 inhibitor activity-%%-GO:0030546-&&-receptor activator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion	G:9606:ANXA2				ANXA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA2	0.45734256	0.12745098	120	4	FALSE	ANXA2	ANXA2	226.8416667	0	120	0	0.80224253	FALSE	0	ANXA2	1082862	0.04497654
792276	taxon:9606	2.33054987	6.89E-04	182305	1902	cadherin 1	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0021983-&&-pituitary gland development-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0034332-&&-adherens junction organization-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0031175-&&-neuron projection development-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0042493-&&-response to drug-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0007416-&&-synapse assembly-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0022408-&&-negative regulation of cell-cell adhesion|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043296-&&-apical junction complex-%%-GO:0005768-&&-endosome-%%-GO:0016600-&&-flotillin complex-%%-GO:0005576-&&-extracellular region-%%-GO:0030027-&&-lamellipodium-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016342-&&-catenin complex-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030506-&&-ankyrin binding	G:9606:CDH1	CDH1	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05213-&&-Endometrial cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05216-&&-Thyroid cancer-%%-hsa05226-&&-Gastric cancer	CDH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH1	0.42908329	0.05838041	120	4	FALSE	CDH1	CDH1	111.9830509	0	119	0	0.77824169	FALSE	1	CDH1	861044	0.02704778
787594	taxon:9606	2.37198677	5.23E-04	179126	1902	nuclear factor of activated T-cells 1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0005528-&&-FK506 binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001225-&&-RNA polymerase II transcription coactivator binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding	G:9606:NFATC1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	NFATC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC1	0.42158751	0.09129754	119	4	FALSE	NFATC1	NFATC1	129.4369748	0	119	0	0.77133554	FALSE	0	NFATC1	773446	0.0331867
787888	taxon:9606	2.27477548	4.20E-04	178653	1902	proteasome 26S subunit, ATPase 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006457-&&-protein folding-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC1			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	PSMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC1	0.43960382	0.22318758	119	4	FALSE	PSMC1	PSMC1	161.2436975	0	119	0	0.78753742	FALSE	0	PSMC1	725082	0.03587467
788575	taxon:9606	2.29226406	7.02E-04	177408	1902	mitogen-activated protein kinase kinase kinase 7	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0043276-&&-anoikis-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:MAP3K7			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MAP3K7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K7	0.43624991	0.09416446	119	4	FALSE	MAP3K7	MAP3K7	125.4358974	0	118	0	0.78462266	FALSE	1	MAP3K7	902722	0.02860245
789019	taxon:9606	2.28659209	3.91E-04	176370	1902	nuclear receptor coactivator 3	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035624-&&-receptor transactivation-%%-GO:2001141-&&-regulation of RNA biosynthetic process-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0016573-&&-histone acetylation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:NCOA3	NCOA3	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	NCOA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA3	0.43733205	0.14706749	119	4	FALSE	NCOA3	NCOA3	169.7094017	0	118	0	0.78556798	FALSE	1	NCOA3	758312	0.0382573
792486	taxon:9606	2.31778793	0.00188325	181946	1902	BCL2, apoptosis regulator	gene	biological_process-&-1&-GO:0030318-&&-melanocyte differentiation-%%-GO:0033033-&&-negative regulation of myeloid cell apoptotic process-%%-GO:0048753-&&-pigment granule organization-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0042493-&&-response to drug-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0009636-&&-response to toxic substance-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0051607-&&-defense response to virus-%%-GO:0010523-&&-negative regulation of calcium ion transport into cytosol-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007015-&&-actin filament organization-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0002931-&&-response to ischemia-%%-GO:0006808-&&-regulation of nitrogen utilization-%%-GO:0048538-&&-thymus development-%%-GO:0006915-&&-apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0009314-&&-response to radiation-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0021747-&&-cochlear nucleus development-%%-GO:0006959-&&-humoral immune response-%%-GO:0043029-&&-T cell homeostasis-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0007569-&&-cell aging-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0001662-&&-behavioral fear response-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0002326-&&-B cell lineage commitment-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0032835-&&-glomerulus development-%%-GO:0045069-&&-regulation of viral genome replication-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0010039-&&-response to iron ion-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:0003014-&&-renal system process-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0001656-&&-metanephros development-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0032848-&&-negative regulation of cellular pH reduction-%%-GO:0051902-&&-negative regulation of mitochondrial depolarization-%%-GO:0016049-&&-cell growth-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0045636-&&-positive regulation of melanocyte differentiation-%%-GO:0046671-&&-negative regulation of retinal cell programmed cell death-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007409-&&-axonogenesis-%%-GO:0043583-&&-ear development-%%-GO:0048536-&&-spleen development-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0022898-&&-regulation of transmembrane transporter activity-%%-GO:0034097-&&-response to cytokine-%%-GO:0035094-&&-response to nicotine-%%-GO:0048599-&&-oocyte development-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0001503-&&-ossification-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0008584-&&-male gonad development-%%-GO:0009791-&&-post-embryonic development-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0031647-&&-regulation of protein stability-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0006582-&&-melanin metabolic process-%%-GO:0010224-&&-response to UV-B-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0010559-&&-regulation of glycoprotein biosynthetic process-%%-GO:0035265-&&-organ growth-%%-GO:0043375-&&-CD8-positive, alpha-beta T cell lineage commitment-%%-GO:0031103-&&-axon regeneration-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0048743-&&-positive regulation of skeletal muscle fiber development|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0016248-&&-channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0015267-&&-channel activity-%%-GO:0002020-&&-protease binding-%%-GO:0051434-&&-BH3 domain binding-%%-GO:0008134-&&-transcription factor binding	G:9606:BCL2	BCL2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa05226-&&-Gastric cancer	BCL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2	0.43144586	0.06822871	119	4	FALSE	BCL2	BCL2	113.974359	0	118	0	0.78036868	FALSE	1	BCL2	2100170	0.0269765
792696	taxon:9606	2.23018749	2.70E-04	181551	1902	DEAD-box helicase 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0006302-&&-double-strand break repair-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0007275-&&-multicellular organism development-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071920-&&-cleavage body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0072669-&&-tRNA-splicing ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0033677-&&-DNA/RNA helicase activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0004518-&&-nuclease activity-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0004527-&&-exonuclease activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX1				DDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX1	0.44839279	0.19256516	119	4	FALSE	DDX1	DDX1	229.7226891	0	119	0	0.79496875	FALSE	0	DDX1	609870	0.04805914
787029	taxon:9606	2.28107767	2.60E-04	180210	1902	heterogeneous nuclear ribonucleoprotein L	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0006396-&&-RNA processing-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0007623-&&-circadian rhythm-%%-GO:1901652-&&-response to peptide-%%-GO:0010467-&&-gene expression-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0045120-&&-pronucleus-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:1990715-&&-mRNA CDS binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:HNRNPL				HNRNPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPL	0.43838928	0.2017991	118	4	FALSE	HNRNPL	HNRNPL	242.9568966	0	117	0	0.78648705	FALSE	1	HNRNPL	635918	0.05442003
787835	taxon:9606	2.37561052	9.39E-04	178739	1902	mitogen-activated protein kinase 6	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007165-&&-signal transduction-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0032156-&&-septin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAPK6			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	MAPK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK6	0.42094442	0.02623688	118	4	FALSE	MAPK6	MAPK6	90.75	0	117	0	0.77073158	FALSE	1	MAPK6	1039610	0.02357893
787872	taxon:9606	2.29888136	2.19E-04	178670	1902	proteasome subunit alpha 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0009615-&&-response to virus-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA2			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA2	0.43499417	0.26686657	118	4	FALSE	PSMA2	PSMA2	168.4827586	0	117	0	0.78351977	FALSE	1	PSMA2	512230	0.03874948
787909	taxon:9606	2.2405861	1.66E-04	178630	1902	polypyrimidine tract binding protein 1	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0051148-&&-negative regulation of muscle cell differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0008187-&&-poly-pyrimidine tract binding-%%-GO:0003723-&&-RNA binding-%%-GO:0036002-&&-pre-mRNA binding	G:9606:PTBP1				PTBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTBP1	0.44631179	0.23373313	118	4	FALSE	PTBP1	PTBP1	236.7413793	0	117	0	0.79323565	FALSE	1	PTBP1	453596	0.05021026
788085	taxon:9606	2.40995746	1.79E-04	178267	1902	ribosomal protein lateral stalk subunit P1	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RPLP1			KEGG-&-1&-hsa03010-&&-Ribosome	RPLP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPLP1	0.41494508	0.38695652	118	4	FALSE	RPLP1	RPLP1	183.4396552	0	117	0	0.76500709	FALSE	1	RPLP1	355800	0.05016317
788278	taxon:9606	2.33338585	1.09E-04	177957	1902	ribosomal protein S12	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS12			KEGG-&-1&-hsa03010-&&-Ribosome	RPS12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS12	0.42856178	0.50398378	118	4	FALSE	RPS12	RPS12	224.9067797	0	118	0	0.77776902	FALSE	0	RPS12	322938	0.05442844
789470	taxon:9606	2.24011344	2.69E-04	175394	1902	RNA binding motif protein 39	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016607-&&-nuclear speck-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM39				RBM39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM39	0.44640596	0.20367956	118	4	FALSE	RBM39	RBM39	215.6864407	0	118	0	0.79331443	FALSE	0	RBM39	626986	0.0456866
792144	taxon:9606	2.27288483	5.56E-04	182521	1902	actinin alpha 1	gene	biological_process-&-1&-GO:0070527-&&-platelet aggregation-%%-GO:0030168-&&-platelet activation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0007015-&&-actin filament organization-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0051639-&&-actin filament network formation-%%-GO:0051271-&&-negative regulation of cellular component movement-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0036344-&&-platelet morphogenesis-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030220-&&-platelet formation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0005884-&&-actin filament-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0031143-&&-pseudopodium-%%-GO:0001726-&&-ruffle-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0051015-&&-actin filament binding	G:9606:ACTN1			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction	ACTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN1	0.4399695	0.0838081	118	4	FALSE	ACTN1	ACTN1	148.8448276	0	117	0	0.78785253	FALSE	1	ACTN1	873624	0.03303226
793108	taxon:9606	2.39435954	2.79E-04	180717	1902	lysine acetyltransferase 2A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0021537-&&-telencephalon development-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0001843-&&-neural tube closure-%%-GO:0030901-&&-midbrain development-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0071929-&&-alpha-tubulin acetylation-%%-GO:0016032-&&-viral process-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0022037-&&-metencephalon development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0001756-&&-somitogenesis-%%-GO:0016578-&&-histone deubiquitination-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0031346-&&-positive regulation of cell projection organization-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0044154-&&-histone H3-K14 acetylation|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0030914-&&-STAGA complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005615-&&-extracellular space-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0010484-&&-H3 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0043997-&&-histone acetyltransferase activity (H4-K12 specific)-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:KAT2A			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	KAT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT2A	0.41764822	0.15742129	118	4	FALSE	KAT2A	KAT2A	167.6637931	0	117	0	0.76760674	FALSE	1	KAT2A	602922	0.04458456
787464	taxon:9606	2.40081928	6.91E-04	179394	1902	MET proto-oncogene, receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:1901299-&&-negative regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0009925-&&-basal plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005008-&&-hepatocyte growth factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:MET	MET	TRUE	KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05144-&&-Malaria-%%-hsa05226-&&-Gastric cancer	MET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MET	0.41652448	0.1006865	117	4	FALSE	MET	MET	96.25217391	0	116	0	0.76653012	FALSE	1	MET	781654	0.02597662
787897	taxon:9606	2.25366315	3.04E-04	178646	1902	proteasome 26S subunit, non-ATPase 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity	G:9606:PSMD1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD1	0.44372204	0.24344238	117	4	FALSE	PSMD1	PSMD1	181.1538462	0	117	0	0.79105614	FALSE	0	PSMD1	637870	0.03908389
787939	taxon:9606	2.23948322	6.33E-04	178537	1902	prolyl 4-hydroxylase subunit beta	gene	biological_process-&-1&-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006457-&&-protein folding-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1902175-&&-regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0046598-&&-positive regulation of viral entry into host cell|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0016222-&&-procollagen-proline 4-dioxygenase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004656-&&-procollagen-proline 4-dioxygenase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:P4HB			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	P4HB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P4HB	0.44653159	0.12814645	117	4	FALSE	P4HB	P4HB	192.7217391	0	116	0	0.79341946	FALSE	1	P4HB	969684	0.04082719
787950	taxon:9606	2.27729636	4.09E-04	178520	1902	p21 (RAC1) activated kinase 1	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006915-&&-apoptotic process-%%-GO:0021549-&&-cerebellum development-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0007409-&&-axonogenesis-%%-GO:0042060-&&-wound healing-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060244-&&-negative regulation of cell proliferation involved in contact inhibition-%%-GO:0006887-&&-exocytosis-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071437-&&-invadopodium-%%-GO:0030424-&&-axon-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0043234-&&-protein complex-%%-GO:0030425-&&-dendrite-%%-GO:0001726-&&-ruffle-%%-GO:0005911-&&-cell-cell junction-%%-GO:0031965-&&-nuclear membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030027-&&-lamellipodium-%%-GO:0030018-&&-Z disc-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:PAK1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04660-&&-T cell receptor signaling pathway	PAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK1	0.4391172	0.11395881	117	4	FALSE	PAK1	PAK1	179.2347826	0	116	0	0.78711727	FALSE	1	PAK1	877802	0.0399465
788538	taxon:9606	2.23066015	4.30E-04	177472	1902	spectrin beta, non-erythrocytic 1	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:1900042-&&-positive regulation of interleukin-2 secretion-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007411-&&-axon guidance-%%-GO:0051693-&&-actin filament capping-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:1903076-&&-regulation of protein localization to plasma membrane-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071709-&&-membrane assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0014069-&&-postsynaptic density-%%-GO:0008091-&&-spectrin-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0032437-&&-cuticular plate-%%-GO:0030673-&&-axolemma-%%-GO:0043234-&&-protein complex-%%-GO:0031430-&&-M band|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0003779-&&-actin binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0030506-&&-ankyrin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding	G:9606:SPTBN1				SPTBN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTBN1	0.44829778	0.12437371	117	4	FALSE	SPTBN1	SPTBN1	218.0854701	0	117	0	0.79488997	FALSE	0	SPTBN1	957300	0.04566519
788599	taxon:9606	2.42193162	5.81E-04	177365	1902	transcription factor 3	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030183-&&-B cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002326-&&-B cell lineage commitment|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:TCF3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	TCF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF3	0.41289357	0.04912281	117	4	FALSE	TCF3	TCF3	101.5217391	0	116	0	0.7630114	FALSE	1	TCF3	791288	0.02843832
790053	taxon:9606	2.3366945	4.31E-04	173998	1902	Fas associated factor 1	gene	biological_process-&-1&-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0008219-&&-cell death-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0045859-&&-regulation of protein kinase activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019887-&&-protein kinase regulator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:FAF1			KEGG-&-1&-hsa04217-&&-Necroptosis	FAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAF1	0.42795496	0.10114416	117	4	FALSE	FAF1	FAF1	150.8173913	0	116	0	0.77721758	FALSE	1	FAF1	721622	0.03674252
790533	taxon:9606	2.32078147	4.10E-04	172560	1902	RNA binding motif protein, X-linked	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0044530-&&-supraspliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0042802-&&-identical protein binding	G:9606:RBMX			KEGG-&-1&-hsa03040-&&-Spliceosome	RBMX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBMX	0.43088934	0.18169336	117	4	FALSE	RBMX	RBMX	197.2086957	0	116	0	0.77986975	FALSE	1	RBMX	718356	0.04681655
791069	taxon:9606	2.37308965	5.78E-04	170152	1902	replication timing regulatory factor 1	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0000723-&&-telomere maintenance-%%-GO:0043247-&&-telomere maintenance in response to DNA damage-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:2001034-&&-positive regulation of double-strand break repair via nonhomologous end joining-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:0007049-&&-cell cycle-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005886-&&-plasma membrane-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0031965-&&-nuclear membrane-%%-GO:0051233-&&-spindle midzone-%%-GO:0016604-&&-nuclear body-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001940-&&-male pronucleus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001939-&&-female pronucleus	G:9606:RIF1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	RIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIF1	0.42139158	0.0375286	117	4	FALSE	RIF1	RIF1	111.1565217	0	116	0	0.77115173	FALSE	1	RIF1	831654	0.02857719
791535	taxon:9606	2.35134709	5.88E-04	168218	1902	SMAD specific E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:1901165-&&-positive regulation of trophoblast cell migration-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0046332-&&-SMAD binding	G:9606:SMURF2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04350-&&-TGF-beta signaling pathway	SMURF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMURF2	0.42528813	0.0617849	117	4	FALSE	SMURF2	SMURF2	106.373913	0	116	0	0.77477548	FALSE	1	SMURF2	730654	0.0264067
791984	taxon:9606	2.38002206	5.73E-04	182775	1902	X-linked inhibitor of apoptosis	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030510-&&-regulation of BMP signaling pathway-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0055070-&&-copper ion homeostasis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1902530-&&-positive regulation of protein linear polyubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:XIAP	XIAP	TRUE	KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05222-&&-Small cell lung cancer	XIAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XIAP	0.42016417	0.08039664	117	4	FALSE	XIAP	XIAP	107.1217391	0	116	0	0.76999632	FALSE	1	XIAP	725176	0.02787091
792186	taxon:9606	2.37088388	6.50E-04	182466	1902	ras homolog family member A	gene	biological_process-&-1&-GO:0036089-&&-cleavage furrow formation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0033688-&&-regulation of osteoblast proliferation-%%-GO:0060193-&&-positive regulation of lipase activity-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0043931-&&-ossification involved in bone maturation-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043297-&&-apical junction assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097498-&&-endothelial tube lumen extension-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1903673-&&-mitotic cleavage furrow formation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0016032-&&-viral process-%%-GO:0061383-&&-trabecula morphogenesis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030168-&&-platelet activation-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1902766-&&-skeletal muscle satellite cell migration-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0016477-&&-cell migration-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0038027-&&-apolipoprotein A-I-mediated signaling pathway-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0090307-&&-mitotic spindle assembly|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0043296-&&-apical junction complex-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030027-&&-lamellipodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0005938-&&-cell cortex-%%-GO:0071944-&&-cell periphery-%%-GO:0005925-&&-focal adhesion-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005768-&&-endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0017022-&&-myosin binding	G:9606:RHOA			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa05133-&&-Pertussis-%%-hsa04022-&&-cGMP-PKG signaling pathway	RHOA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOA	0.42178363	0.05293669	117	4	FALSE	RHOA	RHOA	103.6869565	0	116	0	0.77151935	FALSE	1	RHOA	770356	0.02662792
787620	taxon:9606	2.42413739	3.61E-04	179078	1902	NME/NM23 nucleoside diphosphate kinase 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0006228-&&-UTP biosynthetic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0018106-&&-peptidyl-histidine phosphorylation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0002762-&&-negative regulation of myeloid leukocyte differentiation-%%-GO:0006183-&&-GTP biosynthetic process-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0060416-&&-response to growth hormone-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007155-&&-cell adhesion-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0045682-&&-regulation of epidermis development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006241-&&-CTP biosynthetic process-%%-GO:0009142-&&-nucleoside triphosphate biosynthetic process-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005882-&&-intermediate filament-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0004550-&&-nucleoside diphosphate kinase activity-%%-GO:0004673-&&-protein histidine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019215-&&-intermediate filament binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:NME2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME2	0.41251787	0.08461419	116	4	FALSE	NME2	NME2	109.754386	0	115	0	0.76264377	FALSE	1	NME2	636122	0.03076938
787874	taxon:9606	2.38695447	2.70E-04	178664	1902	proteasome subunit beta 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB1			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB1	0.41894389	0.20464768	116	4	FALSE	PSMB1	PSMB1	134.3534483	0	116	0	0.76884092	FALSE	0	PSMB1	497272	0.03538661
788821	taxon:9606	2.30833465	6.25E-04	176808	1902	ubiquitin conjugating enzyme E2 L3	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0008283-&&-cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2L3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease	UBE2L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2L3	0.43321275	0.08228536	116	4	FALSE	UBE2L3	UBE2L3	137	0	115	0	0.78194423	FALSE	1	UBE2L3	830082	0.03193531
789026	taxon:9606	2.30171735	3.15E-04	176345	1902	structural maintenance of chromosomes 1A	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0009314-&&-response to radiation-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008278-&&-cohesin complex-%%-GO:0030893-&&-meiotic cohesin complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0036033-&&-mediator complex binding	G:9606:SMC1A			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis	SMC1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC1A	0.43445821	0.15339233	116	4	FALSE	SMC1A	SMC1A	203.7192983	0	115	0	0.78304711	FALSE	1	SMC1A	732856	0.04685155
790774	taxon:9606	2.42413739	3.61E-04	154878	1902	NME1-NME2 readthrough	gene		G:9606:NME1-NME2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME1-NME2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME1-NME2	0.41251787	0.08461419	116	4	FALSE	NME1-NME2	NME1-NME2	109.754386	0	115	0	0.76264377	FALSE	1	NME1-NME2	636122	0.03076938
787548	taxon:9606	2.34583268	5.36E-04	179209	1902	moesin	gene	biological_process-&-1&-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0071394-&&-cellular response to testosterone stimulus-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0050900-&&-leukocyte migration-%%-GO:2000401-&&-regulation of lymphocyte migration-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0031528-&&-microvillus membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0045177-&&-apical part of cell-%%-GO:0001931-&&-uropod-%%-GO:0031143-&&-pseudopodium-%%-GO:0030175-&&-filopodium-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0072562-&&-blood microparticle-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005102-&&-receptor binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:MSN			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSN	0.42628786	0.10493047	115	4	FALSE	MSN	MSN	138.1238938	0	114	0	0.77569455	FALSE	1	MSN	799982	0.03405607
787875	taxon:9606	2.28485899	4.16E-04	178667	1902	proteasome subunit alpha 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA5			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA5	0.43766377	0.2317315	115	4	FALSE	PSMA5	PSMA5	168.4695652	0	115	0	0.78585684	FALSE	0	PSMA5	724490	0.03798245
788427	taxon:9606	2.29273673	3.03E-04	177691	1902	serine and arginine rich splicing factor 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SRSF2			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF2	0.43615998	0.13147914	115	4	FALSE	SRSF2	SRSF2	189.9292035	0	114	0	0.78454388	FALSE	1	SRSF2	698752	0.04321863
789921	taxon:9606	2.4195683	1.47E-04	157977	1902	H3 histone, family 3A, pseudogene 4	gene		G:9606:H3F3AP4				H3F3AP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3AP4	0.41329687	0.16018307	115	4	FALSE	H3F3AP4	H3F3AP4	152.1565217	0	115	0	0.76340528	FALSE	0	H3F3AP4	475126	0.04226778
791919	taxon:9606	2.39026312	0.00127717	182873	1902	albumin	gene	biological_process-&-1&-GO:0019836-&&-hemolysis by symbiont of host erythrocytes-%%-GO:0001895-&&-retina homeostasis-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0051659-&&-maintenance of mitochondrion location-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006810-&&-transport-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0043252-&&-sodium-independent organic anion transport-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016209-&&-antioxidant activity-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0015643-&&-toxic substance binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0008144-&&-drug binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019825-&&-oxygen binding-%%-GO:0003677-&&-DNA binding	G:9606:ALB	ALB	TRUE	KEGG-&-1&-hsa04918-&&-Thyroid hormone synthesis	ALB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALB	0.41836398	0.03255373	115	4	FALSE	ALB	ALB	88.39823009	0	114	0	0.76828948	FALSE	1	ALB	1197084	0.02353194
792338	taxon:9606	2.34394202	2.65E-04	182210	1902	chromodomain helicase DNA binding protein 4	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0051225-&&-spindle assembly-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0072553-&&-terminal button organization-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0016581-&&-NuRD complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:CHD4			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	CHD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD4	0.42663171	0.16466498	115	4	FALSE	CHD4	CHD4	201.5663717	0	114	0	0.77600966	FALSE	1	CHD4	679216	0.04936289
793283	taxon:9606	2.4195683	1.47E-04	180376	1902	H3 histone family member 3A	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0031508-&&-pericentric heterochromatin assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1902340-&&-negative regulation of chromosome condensation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0007286-&&-spermatid development-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0008584-&&-male gonad development-%%-GO:0048477-&&-oogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007566-&&-embryo implantation-%%-GO:0031509-&&-telomeric heterochromatin assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0009725-&&-response to hormone-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007338-&&-single fertilization-%%-GO:0032200-&&-telomere organization-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001740-&&-Barr body-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:H3F3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	H3F3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3A	0.41329687	0.16018307	115	4	FALSE	H3F3A	H3F3A	152.1565217	0	115	0	0.76340528	FALSE	0	H3F3A	475126	0.04226778
793286	taxon:9606	2.4195683	1.47E-04	180375	1902	H3 histone family member 3B	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0031508-&&-pericentric heterochromatin assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1902340-&&-negative regulation of chromosome condensation-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0007286-&&-spermatid development-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0090230-&&-regulation of centromere complex assembly-%%-GO:0008584-&&-male gonad development-%%-GO:0048477-&&-oogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007566-&&-embryo implantation-%%-GO:0031509-&&-telomeric heterochromatin assembly-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0009725-&&-response to hormone-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007338-&&-single fertilization-%%-GO:0032200-&&-telomere organization-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0000788-&&-nuclear nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0001740-&&-Barr body-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:H3F3B			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	H3F3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H3F3B	0.41329687	0.16018307	115	4	FALSE	H3F3B	H3F3B	152.1565217	0	115	0	0.76340528	FALSE	0	H3F3B	475126	0.04226778
787436	taxon:9606	2.29053096	5.74E-04	179442	1902	galectin 3 binding protein	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007155-&&-cell adhesion-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006968-&&-cellular defense response-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0072562-&&-blood microparticle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity	G:9606:LGALS3BP				LGALS3BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS3BP	0.43658	0.14687902	114	4	FALSE	LGALS3BP	LGALS3BP	185.3214286	0	113	0	0.78491151	FALSE	1	LGALS3BP	829106	0.04211996
787896	taxon:9606	2.33858516	2.08E-04	178647	1902	proteasome 26S subunit, ATPase 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC6			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC6	0.42760897	0.25273488	114	4	FALSE	PSMC6	PSMC6	161.125	0	113	0	0.77690247	FALSE	1	PSMC6	475888	0.03924135
788216	taxon:9606	2.31101308	3.62E-04	178060	1902	UPF1, RNA helicase and ATPase	gene	biological_process-&-1&-GO:0006449-&&-regulation of translational termination-%%-GO:0032201-&&-telomere maintenance via semi-conservative replication-%%-GO:0006260-&&-DNA replication-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0009048-&&-dosage compensation by inactivation of X chromosome-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006281-&&-DNA repair-%%-GO:0000294-&&-nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0000723-&&-telomere maintenance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol-%%-GO:0044530-&&-supraspliceosomal complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005524-&&-ATP binding	G:9606:UPF1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF1	0.43271066	0.15416861	114	4	FALSE	UPF1	UPF1	197.1491228	0	114	0	0.78149782	FALSE	0	UPF1	699148	0.04603932
788495	taxon:9606	2.29557271	1.86E-04	177549	1902	small nuclear ribonucleoprotein D1 polypeptide	gene	biological_process-&-1&-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005634-&&-nucleus-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0097526-&&-spliceosomal tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding	G:9606:SNRPD1			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD1	0.43562114	0.25011644	114	4	FALSE	SNRPD1	SNRPD1	212.3947368	0	114	0	0.78407121	FALSE	0	SNRPD1	471984	0.04850302
788561	taxon:9606	2.3018749	6.14E-04	177439	1902	spleen associated tyrosine kinase	gene	biological_process-&-1&-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0010543-&&-regulation of platelet activation-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0045087-&&-innate immune response-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032928-&&-regulation of superoxide anion generation-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002283-&&-neutrophil activation involved in immune response-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0045401-&&-positive regulation of interleukin-3 biosynthetic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0016032-&&-viral process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043313-&&-regulation of neutrophil degranulation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0002250-&&-adaptive immune response-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0002554-&&-serotonin secretion by platelet-%%-GO:0045425-&&-positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0042991-&&-transcription factor import into nucleus-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0090237-&&-regulation of arachidonic acid secretion-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0008283-&&-cell proliferation-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0031623-&&-receptor internalization-%%-GO:0045588-&&-positive regulation of gamma-delta T cell differentiation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0043366-&&-beta selection-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0019370-&&-leukotriene biosynthetic process-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0071226-&&-cellular response to molecule of fungal origin-%%-GO:0006954-&&-inflammatory response-%%-GO:0001945-&&-lymph vessel development-%%-GO:0002366-&&-leukocyte activation involved in immune response|cellular_component-&-1&-GO:0019815-&&-B cell receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0032009-&&-early phagosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005178-&&-integrin binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0035325-&&-Toll-like receptor binding	G:9606:SYK			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway	SYK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYK	0.43442847	0.14333977	114	4	FALSE	SYK	SYK	138.6875	0	113	0	0.78302085	FALSE	1	SYK	870136	0.03200727
788826	taxon:9606	2.33858516	6.32E-04	176806	1902	ubiquitin conjugating enzyme E2 N	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0031058-&&-positive regulation of histone modification-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006301-&&-postreplication repair-%%-GO:0033182-&&-regulation of histone ubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0035370-&&-UBC13-UEV1A complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031372-&&-UBC13-MMS2 complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2N			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2N	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2N	0.42760897	0.07351995	114	4	FALSE	UBE2N	UBE2N	129.375	0	113	0	0.77690247	FALSE	1	UBE2N	872360	0.03152643
790248	taxon:9606	2.37245943	6.62E-04	173528	1902	neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0007588-&&-excretion-%%-GO:0010038-&&-response to metal ion-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:0030104-&&-water homeostasis-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0019058-&&-viral life cycle-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:2001288-&&-positive regulation of caveolin-mediated endocytosis-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:1902306-&&-negative regulation of sodium ion transmembrane transport-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019871-&&-sodium channel inhibitor activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0017080-&&-sodium channel regulator activity	G:9606:NEDD4L			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04530-&&-Tight junction-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	NEDD4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD4L	0.42150352	0.0453668	114	4	FALSE	NEDD4L	NEDD4L	106.6964286	0	113	0	0.77125676	FALSE	1	NEDD4L	838268	0.02747182
790910	taxon:9606	2.37860406	2.36E-04	170723	1902	sirtuin 6	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0031648-&&-protein destabilization-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0061647-&&-histone H3-K9 modification-%%-GO:1902732-&&-positive regulation of chondrocyte proliferation-%%-GO:0031940-&&-positive regulation of chromatin silencing at telomere-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0003247-&&-post-embryonic cardiac muscle cell growth involved in heart morphogenesis-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:1905564-&&-positive regulation of vascular endothelial cell proliferation-%%-GO:1990619-&&-histone H3-K9 deacetylation-%%-GO:1905555-&&-positive regulation blood vessel branching-%%-GO:0006284-&&-base-excision repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1905549-&&-positive regulation of telomeric heterochromatin assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005724-&&-nuclear telomeric heterochromatin|molecular_function-&-1&-GO:0017136-&&-NAD-dependent histone deacetylase activity-%%-GO:0070403-&&-NAD+ binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046969-&&-NAD-dependent histone deacetylase activity (H3-K9 specific)-%%-GO:0003956-&&-NAD(P)+-protein-arginine ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:SIRT6			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05230-&&-Central carbon metabolism in cancer	SIRT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT6	0.42041465	0.05884179	114	4	FALSE	SIRT6	SIRT6	131.3859649	0	114	0	0.77023266	FALSE	0	SIRT6	448282	0.034031
791630	taxon:9606	2.5274933	2.48E-04	167738	1902	histone deacetylase 11	gene	biological_process-&-1&-GO:0014003-&&-oligodendrocyte development-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006325-&&-chromatin organization-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)	G:9606:HDAC11			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC11	0.39564892	0.06070486	114	4	FALSE	HDAC11	HDAC11	113.5526316	0	114	0	0.74541778	FALSE	0	HDAC11	455230	0.03875293
792220	taxon:9606	2.28218056	4.11E-04	182392	1902	ATPase Na+/K+ transporting subunit alpha 1	gene	biological_process-&-1&-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:1903416-&&-response to glycoside-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0045823-&&-positive regulation of heart contraction-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0042493-&&-response to drug-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:0045989-&&-positive regulation of striated muscle contraction-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0031947-&&-negative regulation of glucocorticoid biosynthetic process-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0016311-&&-dephosphorylation-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0010107-&&-potassium ion import-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030315-&&-T-tubule-%%-GO:0042470-&&-melanosome-%%-GO:0042383-&&-sarcolemma-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0016021-&&-integral component of membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005794-&&-Golgi apparatus-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031402-&&-sodium ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:1990239-&&-steroid hormone binding-%%-GO:0030506-&&-ankyrin binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0043531-&&-ADP binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:ATP1A1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04978-&&-Mineral absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1A1	0.43817742	0.12063344	114	4	FALSE	ATP1A1	ATP1A1	159.7192983	0	114	0	0.78630324	FALSE	0	ATP1A1	799796	0.0358256
792568	taxon:9606	2.39435954	5.18E-04	181796	1902	cyclin A2	gene	biological_process-&-1&-GO:0071373-&&-cellular response to luteinizing hormone stimulus-%%-GO:0044843-&&-cell cycle G1/S phase transition-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0051301-&&-cell division-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0033762-&&-response to glucagon-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:0016032-&&-viral process-%%-GO:0071314-&&-cellular response to cocaine-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090102-&&-cochlea development-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0097124-&&-cyclin A2-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0001939-&&-female pronucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0001940-&&-male pronucleus-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0097472-&&-cyclin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding	G:9606:CCNA2	CCNA2	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	CCNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNA2	0.41764822	0.10601673	114	4	FALSE	CCNA2	CCNA2	122.4375	0	113	0	0.76760674	FALSE	1	CCNA2	727602	0.03250569
793226	taxon:9606	2.38774224	6.16E-04	180497	1902	heat shock protein family E (Hsp10) member 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:HSPE1				HSPE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPE1	0.41880567	0.10448688	114	4	FALSE	HSPE1	HSPE1	123.0789474	0	114	0	0.76870963	FALSE	0	HSPE1	874836	0.03242102
787435	taxon:9606	2.31243107	0.00161204	179443	1902	galectin 3	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:2000521-&&-negative regulation of immunological synapse formation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0070232-&&-regulation of T cell apoptotic process-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0008380-&&-RNA splicing-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0006397-&&-mRNA processing-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0071674-&&-mononuclear cell migration-%%-GO:2001189-&&-negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell-%%-GO:0050918-&&-positive chemotaxis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0043236-&&-laminin binding-%%-GO:0019863-&&-IgE binding	G:9606:LGALS3	LGALS3	TRUE		LGALS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS3	0.43244532	0.03521704	113	4	FALSE	LGALS3	LGALS3	102.5765766	0	112	0	0.78126149	FALSE	1	LGALS3	1539504	0.02411241
787946	taxon:9606	2.25712935	4.41E-04	178524	1902	peroxiredoxin 1	gene	biological_process-&-1&-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0001895-&&-retina homeostasis-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0001501-&&-skeletal system development-%%-GO:0008283-&&-cell proliferation-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0034101-&&-erythrocyte homeostasis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0004601-&&-peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:PRDX1			KEGG-&-1&-hsa04146-&&-Peroxisome	PRDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX1	0.44304063	0.11875512	113	4	FALSE	PRDX1	PRDX1	215.1261261	0	112	0	0.79047844	FALSE	1	PRDX1	836800	0.0466351
788168	taxon:9606	2.36773279	3.34E-04	178138	1902	RAD23 homolog B, nucleotide excision repair protein	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006457-&&-protein folding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0048568-&&-embryonic organ development-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0071942-&&-XPC complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:RAD23B			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RAD23B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD23B	0.42234496	0.11472819	113	4	FALSE	RAD23B	RAD23B	156.6902655	0	113	0	0.77204454	FALSE	0	RAD23B	670960	0.03988834
788289	taxon:9606	2.38758469	1.01E-04	177944	1902	ribosomal protein S21	gene	biological_process-&-1&-GO:0000461-&&-endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0000447-&&-endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0047485-&&-protein N-terminus binding	G:9606:RPS21			KEGG-&-1&-hsa03010-&&-Ribosome	RPS21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS21	0.41883331	0.4522756	113	4	FALSE	RPS21	RPS21	214.2389381	0	113	0	0.76873589	FALSE	0	RPS21	285178	0.05658247
788295	taxon:9606	2.46431385	1.44E-04	177937	1902	ribosomal protein S28	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015935-&&-small ribosomal subunit-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPS28			KEGG-&-1&-hsa03010-&&-Ribosome	RPS28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS28	0.40579247	0.42541087	113	4	FALSE	RPS28	RPS28	200.3982301	0	113	0	0.75594769	FALSE	0	RPS28	391684	0.06023391
788430	taxon:9606	2.32093903	1.97E-04	177686	1902	serine and arginine rich splicing factor 7	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SRSF7			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF7	0.43086009	0.22771808	113	4	FALSE	SRSF7	SRSF7	217.1238938	0	113	0	0.7798435	FALSE	0	SRSF7	510648	0.05153665
788441	taxon:9606	2.33354341	2.83E-04	177671	1902	SKI proto-oncogene	gene	biological_process-&-1&-GO:0032926-&&-negative regulation of activin receptor signaling pathway-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060325-&&-face morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031064-&&-negative regulation of histone deacetylation-%%-GO:0010626-&&-negative regulation of Schwann cell proliferation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0043585-&&-nose morphogenesis-%%-GO:0014902-&&-myotube differentiation-%%-GO:0048870-&&-cell motility-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060021-&&-palate development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0001843-&&-neural tube closure-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0043010-&&-camera-type eye development-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048666-&&-neuron development-%%-GO:0008283-&&-cell proliferation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0046811-&&-histone deacetylase inhibitor activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:SKI	SKI	TRUE		SKI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKI	0.42853285	0.09107289	113	4	FALSE	SKI	SKI	148.2342342	0	112	0	0.77774277	FALSE	1	SKI	521608	0.03582693
788691	taxon:9606	2.48889239	0.00302892	177174	1902	tumor necrosis factor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0007254-&&-JNK cascade-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0031622-&&-positive regulation of fever generation-%%-GO:0035509-&&-negative regulation of myosin-light-chain-phosphatase activity-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0002925-&&-positive regulation of humoral immune response mediated by circulating immunoglobulin-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:2000334-&&-positive regulation of blood microparticle formation-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:2000343-&&-positive regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0043242-&&-negative regulation of protein complex disassembly-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0060559-&&-positive regulation of calcidiol 1-monooxygenase activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009615-&&-response to virus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904999-&&-positive regulation of leukocyte adhesion to arterial endothelial cell-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0061048-&&-negative regulation of branching involved in lung morphogenesis-%%-GO:0045994-&&-positive regulation of translational initiation by iron-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060557-&&-positive regulation of vitamin D biosynthetic process-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0060693-&&-regulation of branching involved in salivary gland morphogenesis-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006954-&&-inflammatory response-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:1901671-&&-positive regulation of superoxide dismutase activity-%%-GO:0051798-&&-positive regulation of hair follicle development-%%-GO:0006959-&&-humoral immune response-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0002740-&&-negative regulation of cytokine secretion involved in immune response-%%-GO:0043243-&&-positive regulation of protein complex disassembly-%%-GO:0051222-&&-positive regulation of protein transport-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0032800-&&-receptor biosynthetic process-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0009651-&&-response to salt stress-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0002439-&&-chronic inflammatory response to antigenic stimulus-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:1903347-&&-negative regulation of bicellular tight junction assembly-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0010693-&&-negative regulation of alkaline phosphatase activity-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002876-&&-positive regulation of chronic inflammatory response to antigenic stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030730-&&-sequestering of triglyceride-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0001891-&&-phagocytic cup-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0002020-&&-protease binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:TNF	TNF	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa05134-&&-Legionellosis-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05310-&&-Asthma-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	TNF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNF	0.40178515	0.03898444	113	4	FALSE	TNF	TNF	65.88288288	0	112	0	0.75185127	FALSE	1	TNF	3476808	0.02107615
788899	taxon:9606	2.28958563	4.54E-04	176651	1902	YY1 transcription factor	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0010225-&&-response to UV-C-%%-GO:0030154-&&-cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0034644-&&-cellular response to UV|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus-%%-GO:0031011-&&-Ino80 complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding	G:9606:YY1				YY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YY1	0.43676025	0.11384111	113	4	FALSE	YY1	YY1	162.3513514	0	112	0	0.78506906	FALSE	1	YY1	756166	0.03677063
789404	taxon:9606	2.38805735	3.36E-04	175550	1902	COP9 signalosome subunit 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0008283-&&-cell proliferation-%%-GO:0022008-&&-neurogenesis-%%-GO:0000338-&&-protein deneddylation-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0030182-&&-neuron differentiation-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004871-&&-signal transducer activity	G:9606:COPS2				COPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS2	0.41875041	0.14791155	113	4	FALSE	COPS2	COPS2	175.1801802	0	112	0	0.76865711	FALSE	1	COPS2	685762	0.04603
789867	taxon:9606	2.29510005	4.49E-04	174483	1902	inner membrane mitochondrial protein	gene	biological_process-&-1&-GO:0042407-&&-cristae formation-%%-GO:0008150-&&-biological_process-%%-GO:0051560-&&-mitochondrial calcium ion homeostasis|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0061617-&&-MICOS complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:IMMT				IMMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IMMT	0.43571085	0.08239148	113	4	FALSE	IMMT	IMMT	160.2342342	0	112	0	0.78414999	FALSE	1	IMMT	833608	0.03653734
792485	taxon:9606	2.26091067	8.97E-04	181947	1902	cyclin D1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0051412-&&-response to corticosterone-%%-GO:0097421-&&-liver regeneration-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051301-&&-cell division-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0007595-&&-lactation-%%-GO:0043627-&&-response to estrogen-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0045471-&&-response to ethanol-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0070141-&&-response to UV-A-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010165-&&-response to X-ray-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0042493-&&-response to drug-%%-GO:0051592-&&-response to calcium ion-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000320-&&-re-entry into mitotic cell cycle-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0033197-&&-response to vitamin E-%%-GO:0032355-&&-response to estradiol-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0044321-&&-response to leptin-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0010039-&&-response to iron ion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0016020-&&-membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:CCND1	CCND1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04530-&&-Tight junction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	CCND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCND1	0.44229965	0.1022113	113	4	FALSE	CCND1	CCND1	161.5765766	0	112	0	0.78984822	FALSE	1	CCND1	1083832	0.03526103
793081	taxon:9606	2.23680479	5.31E-04	180785	1902	mechanistic target of rapamycin	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1904193-&&-negative regulation of cholangiocyte apoptotic process-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0014736-&&-negative regulation of muscle atrophy-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0032868-&&-response to insulin-%%-GO:1904000-&&-positive regulation of eating behavior-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0031929-&&-TOR signaling-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0042060-&&-wound healing-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007584-&&-response to nutrient-%%-GO:0031295-&&-T cell costimulation-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0042220-&&-response to cocaine-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0007165-&&-signal transduction-%%-GO:1904197-&&-positive regulation of granulosa cell proliferation-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0007569-&&-cell aging-%%-GO:0016049-&&-cell growth-%%-GO:0016310-&&-phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0043200-&&-response to amino acid-%%-GO:0030163-&&-protein catabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0055013-&&-cardiac muscle cell development-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045727-&&-positive regulation of translation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032095-&&-regulation of response to food-%%-GO:0016236-&&-macroautophagy-%%-GO:0043276-&&-anoikis-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0007616-&&-long-term memory-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0007281-&&-germ cell development-%%-GO:1904058-&&-positive regulation of sensory perception of pain-%%-GO:0031641-&&-regulation of myelination-%%-GO:0021510-&&-spinal cord development-%%-GO:0031998-&&-regulation of fatty acid beta-oxidation-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0035176-&&-social behavior-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1904056-&&-positive regulation of cholangiocyte proliferation-%%-GO:0043610-&&-regulation of carbohydrate utilization-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007420-&&-brain development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0040007-&&-growth-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0031529-&&-ruffle organization-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0090559-&&-regulation of membrane permeability-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043278-&&-response to morphine-%%-GO:1904213-&&-negative regulation of iodide transmembrane transport-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0009791-&&-post-embryonic development-%%-GO:0006950-&&-response to stress-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:1904206-&&-positive regulation of skeletal muscle hypertrophy-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0031931-&&-TORC1 complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005764-&&-lysosome-%%-GO:0031932-&&-TORC2 complex-%%-GO:0012505-&&-endomembrane system-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001156-&&-TFIIIC-class transcription factor binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0001031-&&-RNA polymerase III type 2 promoter DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0001032-&&-RNA polymerase III type 3 promoter DNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001030-&&-RNA polymerase III type 1 promoter DNA binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:MTOR	MTOR	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04136-&&-Autophagy - other-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	MTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTOR	0.44706628	0.0971335	113	4	FALSE	MTOR	MTOR	155.8288288	0	112	0	0.79386587	FALSE	1	MTOR	829252	0.03286265
787330	taxon:9606	2.25350559	5.91E-04	179656	1902	keratin 18	gene	biological_process-&-1&-GO:0043000-&&-Golgi to plasma membrane CFTR protein transport-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0031424-&&-keratinization-%%-GO:0007049-&&-cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0070268-&&-cornification-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0045095-&&-keratin filament-%%-GO:0005730-&&-nucleolus-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion	G:9606:KRT18	KRT18	TRUE	KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04915-&&-Estrogen signaling pathway	KRT18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT18	0.44375306	0.11943286	112	4	FALSE	KRT18	KRT18	202.5545455	0	111	0	0.7910824	FALSE	1	KRT18	977764	0.043616
788476	taxon:9606	2.35418308	4.50E-04	177575	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0022008-&&-neurogenesis-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0008080-&&-N-acetyltransferase activity	G:9606:SMARCE1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCE1	0.4247758	0.12162162	112	4	FALSE	SMARCE1	SMARCE1	154.7410714	0	112	0	0.77430282	FALSE	0	SMARCE1	900786	0.03855398
788640	taxon:9606	2.29194895	4.29E-04	177274	1902	ubiquitin like modifier activating enzyme 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0030867-&&-rough endoplasmic reticulum membrane-%%-GO:0000792-&&-heterochromatin-%%-GO:0010008-&&-endosome membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030057-&&-desmosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004839-&&-ubiquitin activating enzyme activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:UBA1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease	UBA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA1	0.43630989	0.09557965	112	4	FALSE	UBA1	UBA1	162.7454546	0	111	0	0.78467517	FALSE	1	UBA1	690806	0.03701299
788843	taxon:9606	2.34536001	3.08E-04	176765	1902	ubiquinol-cytochrome c reductase core protein II	gene	biological_process-&-1&-GO:0006627-&&-protein processing involved in protein targeting to mitochondrion-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0009060-&&-aerobic respiration|cellular_component-&-1&-GO:0005750-&&-mitochondrial respiratory chain complex III-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:UQCRC2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	UQCRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UQCRC2	0.42637377	0.1483269	112	4	FALSE	UQCRC2	UQCRC2	139.5267857	0	112	0	0.77577333	FALSE	0	UQCRC2	555196	0.03427957
789666	taxon:9606	2.36253348	2.78E-04	174943	1902	tubulin gamma complex associated protein 3	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0051298-&&-centrosome duplication-%%-GO:0007338-&&-single fertilization-%%-GO:0031122-&&-cytoplasmic microtubule organization|cellular_component-&-1&-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005813-&&-centrosome-%%-GO:0005816-&&-spindle pole body-%%-GO:0005819-&&-spindle-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0016020-&&-membrane-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005827-&&-polar microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:TUBGCP3				TUBGCP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP3	0.42327442	0.11872587	112	4	FALSE	TUBGCP3	TUBGCP3	149.4107143	0	112	0	0.77291109	FALSE	0	TUBGCP3	505246	0.03772096
789747	taxon:9606	2.3067591	5.42E-04	174772	1902	ARP2 actin related protein 2 homolog	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0008306-&&-associative learning-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051653-&&-spindle localization-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0060271-&&-cilium assembly-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016482-&&-cytosolic transport-%%-GO:0033206-&&-meiotic cytokinesis-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0035984-&&-cellular response to trichostatin A-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0016344-&&-meiotic chromosome movement towards spindle pole|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030478-&&-actin cap-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane-%%-GO:0071437-&&-invadopodium-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding	G:9606:ACTR2			KEGG-&-1&-hsa04530-&&-Tight junction	ACTR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTR2	0.43350864	0.13819176	112	4	FALSE	ACTR2	ACTR2	162	0	112	0	0.78220682	FALSE	0	ACTR2	876862	0.03767027
790876	taxon:9606	2.35449819	3.62E-04	170793	1902	UBX domain protein 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1903094-&&-negative regulation of protein K48-linked deubiquitination-%%-GO:2000157-&&-negative regulation of ubiquitin-specific protease activity-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1904293-&&-negative regulation of ERAD pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0000502-&&-proteasome complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0071796-&&-K6-linked polyubiquitin binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBXN1				UBXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN1	0.42471895	0.09090909	112	4	FALSE	UBXN1	UBXN1	131.8363636	0	111	0	0.7742503	FALSE	1	UBXN1	597930	0.03289698
791304	taxon:9606	2.44761305	0.00115424	169283	1902	ubiquilin 4	gene	biological_process-&-1&-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1901097-&&-negative regulation of autophagosome maturation-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBQLN4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UBQLN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBQLN4	0.40856131	0.03619683	112	4	FALSE	UBQLN4	UBQLN4	76.50909091	0	111	0	0.75873116	FALSE	1	UBQLN4	1195086	0.02255653
792520	taxon:9606	2.21143847	8.95E-04	181858	1902	calreticulin	gene	biological_process-&-1&-GO:0022417-&&-protein maturation by protein folding-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0002502-&&-peptide antigen assembly with MHC class I protein complex-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0033574-&&-response to testosterone-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0032355-&&-response to estradiol-%%-GO:0033144-&&-negative regulation of intracellular steroid hormone receptor signaling pathway-%%-GO:1990668-&&-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:2000510-&&-positive regulation of dendritic cell chemotaxis-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0006457-&&-protein folding-%%-GO:0090398-&&-cellular senescence-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050821-&&-protein stabilization-%%-GO:0051208-&&-sequestering of calcium ion-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0034504-&&-protein localization to nucleus|cellular_component-&-1&-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005844-&&-polysome-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0033018-&&-sarcoplasmic reticulum lumen-%%-GO:0042824-&&-MHC class I peptide loading complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0042562-&&-hormone binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0005178-&&-integrin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0042277-&&-peptide binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CALR			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CALR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALR	0.45219436	0.10692244	112	4	FALSE	CALR	CALR	177.9727273	0	111	0	0.79809359	FALSE	1	CALR	1192610	0.03632281
787682	taxon:9606	2.24893651	6.85E-04	178963	1902	phosphoinositide-3-kinase regulatory subunit 2	gene	biological_process-&-1&-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:PIK3R2			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R2	0.44465462	0.14594595	111	4	FALSE	PIK3R2	PIK3R2	164.9369369	0	111	0	0.79184392	FALSE	0	PIK3R2	961046	0.03536949
787873	taxon:9606	2.23995588	4.49E-04	178665	1902	proteasome subunit alpha 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0098794-&&-postsynapse-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA7			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA7	0.44643736	0.26571526	111	4	FALSE	PSMA7	PSMA7	195.5412844	0	110	0	0.79334069	FALSE	1	PSMA7	783782	0.04138246
788285	taxon:9606	2.38285804	1.81E-04	177954	1902	ribosomal protein S15	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0000056-&&-ribosomal small subunit export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS15			KEGG-&-1&-hsa03010-&&-Ribosome	RPS15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS15	0.41966411	0.47108927	111	4	FALSE	RPS15	RPS15	189.5495496	0	111	0	0.76952366	FALSE	0	RPS15	335316	0.04938524
789593	taxon:9606	2.32960454	3.83E-04	175104	1902	SEC16 homolog A, endoplasmic reticulum export factor	gene	biological_process-&-1&-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0015031-&&-protein transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEC16A				SEC16A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC16A	0.42925741	0.10532351	111	4	FALSE	SEC16A	SEC16A	160.972973	0	111	0	0.77839924	FALSE	0	SEC16A	670634	0.03861467
789866	taxon:9606	2.30439578	2.32E-04	174480	1902	splicing factor 3b subunit 2	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SF3B2			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B2	0.43395323	0.17133497	111	4	FALSE	SF3B2	SF3B2	217.018018	0	111	0	0.7826007	FALSE	0	SF3B2	581784	0.05021032
790861	taxon:9606	2.52780841	2.53E-04	170857	1902	anillin actin binding protein	gene	biological_process-&-1&-GO:0000921-&&-septin ring assembly-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0090521-&&-glomerular visceral epithelial cell migration|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005826-&&-actomyosin contractile ring|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0045296-&&-cadherin binding	G:9606:ANLN				ANLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANLN	0.3955996	0.11809992	111	4	FALSE	ANLN	ANLN	90.73873874	0	111	0	0.74536526	FALSE	0	ANLN	419208	0.03103069
792333	taxon:9606	2.40696392	3.68E-04	182214	1902	regulator of chromosome condensation 1	gene	biological_process-&-1&-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051225-&&-spindle assembly-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0005087-&&-Ran guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:RCC1				RCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCC1	0.41546115	0.14780836	111	4	FALSE	RCC1	RCC1	175.2568807	0	110	0	0.76550601	FALSE	1	RCC1	712770	0.04767446
787237	taxon:9606	2.28296833	5.87E-04	179816	1902	interleukin 1 receptor associated kinase 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0034605-&&-cellular response to heat-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0001959-&&-regulation of cytokine-mediated signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0045323-&&-interleukin-1 receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:IRAK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05133-&&-Pertussis	IRAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRAK1	0.43802622	0.10903427	110	4	FALSE	IRAK1	IRAK1	150.8148148	0	109	0	0.78617194	FALSE	1	IRAK1	792108	0.03380325
787262	taxon:9606	2.33448873	8.38E-04	179783	1902	Janus kinase 2	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:1902728-&&-positive regulation of growth factor dependent skeletal muscle satellite cell proliferation-%%-GO:0042977-&&-activation of JAK2 kinase activity-%%-GO:0060399-&&-positive regulation of growth hormone receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0031103-&&-axon regeneration-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007165-&&-signal transduction-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0070671-&&-response to interleukin-12-%%-GO:0002250-&&-adaptive immune response-%%-GO:1904037-&&-positive regulation of epithelial cell apoptotic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042506-&&-tyrosine phosphorylation of Stat5 protein-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0031959-&&-mineralocorticoid receptor signaling pathway-%%-GO:0046677-&&-response to antibiotic-%%-GO:0035722-&&-interleukin-12-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0042503-&&-tyrosine phosphorylation of Stat3 protein-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0061180-&&-mammary gland epithelium development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007498-&&-mesoderm development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0033194-&&-response to hydroperoxide-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0050867-&&-positive regulation of cell activation-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0035409-&&-histone H3-Y41 phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042508-&&-tyrosine phosphorylation of Stat1 protein-%%-GO:0007596-&&-blood coagulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0005925-&&-focal adhesion-%%-GO:0016363-&&-nuclear matrix-%%-GO:0045121-&&-membrane raft-%%-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0031904-&&-endosome lumen|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0020037-&&-heme binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0033130-&&-acetylcholine receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005131-&&-growth hormone receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0035401-&&-histone kinase activity (H3-Y41 specific)-%%-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005143-&&-interleukin-12 receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:JAK2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK2	0.42835932	0.13049498	110	4	FALSE	JAK2	JAK2	124.8611111	0	109	0	0.77758521	FALSE	1	JAK2	1088356	0.03022315
788147	taxon:9606	2.47392469	4.24E-04	178163	1902	RAB1A, member RAS oncogene family	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0019068-&&-virion assembly-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:1903020-&&-positive regulation of glycoprotein metabolic process-%%-GO:0072606-&&-interleukin-8 secretion-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0016477-&&-cell migration-%%-GO:0007030-&&-Golgi organization-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0006914-&&-autophagy-%%-GO:0060271-&&-cilium assembly-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0006897-&&-endocytosis-%%-GO:0090110-&&-cargo loading into COPII-coated vesicle-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0030252-&&-growth hormone secretion-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0032402-&&-melanosome transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005769-&&-early endosome-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0045296-&&-cadherin binding	G:9606:RAB1A			KEGG-&-1&-hsa05134-&&-Legionellosis	RAB1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB1A	0.40421602	0.08023353	110	4	FALSE	RAB1A	RAB1A	96.08181818	0	110	0	0.75434589	FALSE	0	RAB1A	560222	0.02949241
788178	taxon:9606	2.283441	5.30E-04	178123	1902	RAN binding protein 2	gene	biological_process-&-1&-GO:0046604-&&-positive regulation of mitotic centrosome separation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007051-&&-spindle organization-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0051642-&&-centrosome localization-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006457-&&-protein folding-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0006409-&&-tRNA export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm-%%-GO:0044614-&&-nuclear pore cytoplasmic filaments-%%-GO:0016020-&&-membrane-%%-GO:0005642-&&-annulate lamellae-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body|molecular_function-&-1&-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019789-&&-SUMO transferase activity	G:9606:RANBP2			KEGG-&-1&-hsa03013-&&-RNA transport	RANBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP2	0.43793556	0.1472828	110	4	FALSE	RANBP2	RANBP2	195.2685185	0	109	0	0.78609317	FALSE	1	RANBP2	830752	0.04376406
788443	taxon:9606	2.31526706	3.57E-04	177667	1902	S-phase kinase associated protein 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:0071460-&&-cellular response to cell-matrix adhesion-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:SKP2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05222-&&-Small cell lung cancer	SKP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKP2	0.43191562	0.11474559	110	4	FALSE	SKP2	SKP2	144.5	0	109	0	0.78078882	FALSE	1	SKP2	602266	0.03384868
788496	taxon:9606	2.3300772	1.73E-04	177548	1902	small nuclear ribonucleoprotein D2 polypeptide	gene	biological_process-&-1&-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding	G:9606:SNRPD2			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD2	0.42917033	0.25268259	110	4	FALSE	SNRPD2	SNRPD2	228.6111111	0	109	0	0.77832047	FALSE	1	SNRPD2	481056	0.05484689
789977	taxon:9606	2.48589885	2.00E-04	174206	1902	synaptopodin	gene	biological_process-&-1&-GO:0008542-&&-visual learning-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:1905355-&&-spine apparatus assembly-%%-GO:0098886-&&-modification of dendritic spine|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0097444-&&-spine apparatus-%%-GO:0030018-&&-Z disc-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:SYNPO			KEGG-&-1&-hsa04530-&&-Tight junction	SYNPO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNPO	0.40226898	0.15996664	110	4	FALSE	SYNPO	SYNPO	96.07272727	0	110	0	0.75235019	FALSE	0	SYNPO	350810	0.0302277
790615	taxon:9606	2.29399716	3.16E-04	171748	1902	ubiquitin protein ligase E3 component n-recognin 5	gene	biological_process-&-1&-GO:0050847-&&-progesterone receptor signaling pathway-%%-GO:2000780-&&-negative regulation of double-strand break repair-%%-GO:1901315-&&-negative regulation of histone H2A K63-linked ubiquitination-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0006281-&&-DNA repair-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBR5			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR5	0.43592033	0.08566978	110	4	FALSE	UBR5	UBR5	159.4259259	0	109	0	0.78433381	FALSE	1	UBR5	646854	0.036299
790875	taxon:9606	2.59524185	4.71E-04	170800	1902	golgi transport 1B	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0007165-&&-signal transduction-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity	G:9606:GOLT1B				GOLT1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLT1B	0.38532054	0.07122602	110	4	FALSE	GOLT1B	GOLT1B	59.45454545	0	110	0	0.73412636	FALSE	0	GOLT1B	489666	0.02394392
792141	taxon:9606	2.28564676	4.72E-04	182525	1902	actinin alpha 4	gene	biological_process-&-1&-GO:0030050-&&-vesicle transport along actin filament-%%-GO:0015031-&&-protein transport-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0051271-&&-negative regulation of cellular component movement-%%-GO:0048549-&&-positive regulation of pinocytosis-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0032417-&&-positive regulation of sodium:proton antiporter activity-%%-GO:1902396-&&-protein localization to bicellular tight junction-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051017-&&-actin filament bundle assembly|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030018-&&-Z disc-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0005829-&&-cytosol-%%-GO:0031143-&&-pseudopodium-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0016604-&&-nuclear body-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005622-&&-intracellular-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003779-&&-actin binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005178-&&-integrin binding-%%-GO:0001882-&&-nucleoside binding-%%-GO:0044325-&&-ion channel binding	G:9606:ACTN4			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction	ACTN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN4	0.43751292	0.11192661	110	4	FALSE	ACTN4	ACTN4	171.0272727	0	110	0	0.78572554	FALSE	0	ACTN4	821422	0.03857433
788142	taxon:9606	2.29588782	3.10E-04	178165	1902	glutaminyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0007420-&&-brain development-%%-GO:0006425-&&-glutaminyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004819-&&-glutamine-tRNA ligase activity	G:9606:QARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa01100-&&-Metabolic pathways	QARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QARS	0.43556135	0.13931363	109	4	FALSE	QARS	QARS	174.7247706	0	109	0	0.7840187	FALSE	0	QARS	581520	0.03999975
788696	taxon:9606	2.40885458	3.16E-04	177167	1902	TNF receptor superfamily member 1B	gene	biological_process-&-1&-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050779-&&-RNA destabilization-%%-GO:0006954-&&-inflammatory response-%%-GO:0007568-&&-aging-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043196-&&-varicosity|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TNFRSF1B	TNFRSF1B	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF1B	0.41513506	0.07670605	109	4	FALSE	TNFRSF1B	TNFRSF1B	121.5700935	0	108	0	0.7651909	FALSE	1	TNFRSF1B	487858	0.033198
789571	taxon:9606	2.36048527	4.96E-04	175158	1902	centrosomal protein 170	gene	cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP170				CEP170	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP170	0.4236417	0.09106354	109	4	FALSE	CEP170	CEP170	130.6330275	0	109	0	0.77325246	FALSE	0	CEP170	740418	0.03286038
789992	taxon:9606	2.33165275	1.79E-04	174179	1902	poly(U) binding splicing factor 60	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding	G:9606:PUF60			KEGG-&-1&-hsa03040-&&-Spliceosome	PUF60	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUF60	0.42888033	0.15852583	109	4	FALSE	PUF60	PUF60	184.8598131	0	108	0	0.77805788	FALSE	1	PUF60	398704	0.04449093
790266	taxon:9606	2.33417363	4.64E-04	173477	1902	KIAA0368	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043248-&&-proteasome assembly|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005813-&&-centrosome-%%-GO:0005770-&&-late endosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0005771-&&-multivesicular body-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:KIAA0368				KIAA0368	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA0368	0.42841714	0.08324839	109	4	FALSE	KIAA0368	KIAA0368	140.8990826	0	109	0	0.77763773	FALSE	0	KIAA0368	688908	0.03415773
791377	taxon:9606	2.28044746	3.21E-04	168895	1902	cell cycle and apoptosis regulator 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:2000003-&&-positive regulation of DNA damage checkpoint-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0090311-&&-regulation of protein deacetylation-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0008380-&&-RNA splicing-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006397-&&-mRNA processing-%%-GO:0009411-&&-response to UV-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007049-&&-cell cycle-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0044609-&&-DBIRD complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:CCAR2				CCAR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCAR2	0.43851043	0.10431532	109	4	FALSE	CCAR2	CCAR2	191.7706422	0	109	0	0.78659209	FALSE	0	CCAR2	700144	0.0429072
792969	taxon:9606	2.28659209	7.64E-04	181065	1902	FK506 binding protein 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0031072-&&-heat shock protein binding	G:9606:FKBP5			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	FKBP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP5	0.43733205	0.07526334	109	4	FALSE	FKBP5	FKBP5	125.4770642	0	109	0	0.78556798	FALSE	0	FKBP5	942812	0.02827127
788551	taxon:9606	2.3499291	3.72E-04	177455	1902	SPT5 homolog, DSIF elongation factor subunit	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0039692-&&-single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006354-&&-DNA-templated transcription, elongation-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0032785-&&-negative regulation of DNA-templated transcription, elongation-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010033-&&-response to organic substance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0032044-&&-DSIF complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:SUPT5H				SUPT5H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT5H	0.42554475	0.09955076	108	4	FALSE	SUPT5H	SUPT5H	144.8962264	0	107	0	0.77501182	FALSE	1	SUPT5H	572294	0.03586681
788643	taxon:9606	2.40932724	2.68E-04	177262	1902	SEM1, 26S proteasome complex subunit	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043248-&&-proteasome assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0005829-&&-cytosol-%%-GO:0032039-&&-integrator complex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEM1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome-%%-hsa03440-&&-Homologous recombination	SEM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEM1	0.41505362	0.15299412	108	4	FALSE	SEM1	SEM1	128.75	0	108	0	0.76511213	FALSE	0	SEM1	423550	0.03515028
789244	taxon:9606	2.37293209	5.31E-04	175901	1902	nuclear receptor coactivator 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0060713-&&-labyrinthine layer morphogenesis-%%-GO:0021766-&&-hippocampus development-%%-GO:0021549-&&-cerebellum development-%%-GO:0044849-&&-estrous cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0007595-&&-lactation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0000435-&&-positive regulation of transcription from RNA polymerase II promoter by galactose-%%-GO:0045925-&&-positive regulation of female receptivity-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0032570-&&-response to progesterone-%%-GO:0002155-&&-regulation of thyroid hormone mediated signaling pathway-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0060179-&&-male mating behavior-%%-GO:0021854-&&-hypothalamus development-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0008584-&&-male gonad development-%%-GO:0032355-&&-response to estradiol-%%-GO:2001038-&&-regulation of cellular response to drug-%%-GO:1904017-&&-cellular response to Thyroglobulin triiodothyronine|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0001012-&&-RNA polymerase II regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0033142-&&-progesterone receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0032403-&&-protein complex binding	G:9606:NCOA1	NCOA1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	NCOA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA1	0.42141956	0.13548967	108	4	FALSE	NCOA1	NCOA1	123.990566	0	107	0	0.77117798	FALSE	1	NCOA1	722262	0.03170632
789944	taxon:9606	2.41830786	4.02E-04	174289	1902	adenosylhomocysteinase like 1	gene	biological_process-&-1&-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0031440-&&-regulation of mRNA 3'-end processing-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0008150-&&-biological_process-%%-GO:0044070-&&-regulation of anion transport-%%-GO:0032412-&&-regulation of ion transmembrane transporter activity-%%-GO:0042045-&&-epithelial fluid transport-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0033353-&&-S-adenosylmethionine cycle-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004013-&&-adenosylhomocysteinase activity	G:9606:AHCYL1			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways	AHCYL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHCYL1	0.41351228	0.07008086	108	4	FALSE	AHCYL1	AHCYL1	96.6509434	0	107	0	0.76361536	FALSE	1	AHCYL1	532976	0.02676442
790361	taxon:9606	2.38506381	1.19E-04	173217	1902	ribosomal protein L13a	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0006412-&&-translation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:1901194-&&-negative regulation of formation of translation preinitiation complex-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0097452-&&-GAIT complex-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0015934-&&-large ribosomal subunit-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL13A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL13A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL13A	0.41927599	0.5832468	108	4	FALSE	RPL13A	RPL13A	227.7962963	0	108	0	0.76915603	FALSE	0	RPL13A	234836	0.05971907
790428	taxon:9606	2.39703797	4.02E-04	173019	1902	large tumor suppressor kinase 2	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0046620-&&-regulation of organ growth-%%-GO:0001828-&&-inner cell mass cellular morphogenesis-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0034613-&&-cellular protein localization-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0035329-&&-hippo signaling-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001827-&&-inner cell mass cell fate commitment-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:LATS2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	LATS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LATS2	0.41718154	0.07834681	108	4	FALSE	LATS2	LATS2	106.5283019	0	107	0	0.76716034	FALSE	1	LATS2	542510	0.02843284
791640	taxon:9606	2.52465732	2.93E-04	167683	1902	centrosomal protein 76	gene	biological_process-&-1&-GO:0046599-&&-regulation of centriole replication-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP76				CEP76	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP76	0.39609336	0.0657667	108	4	FALSE	CEP76	CEP76	98.47222222	0	108	0	0.74589045	FALSE	0	CEP76	402434	0.03331638
793285	taxon:9606	2.28659209	4.67E-04	180372	1902	hydroxysteroid 17-beta dehydrogenase 10	gene	biological_process-&-1&-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0070901-&&-mitochondrial tRNA methylation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0090646-&&-mitochondrial tRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0047015-&&-3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008709-&&-cholate 7-alpha-dehydrogenase activity-%%-GO:0030283-&&-testosterone dehydrogenase [NAD(P)] activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:HSD17B10			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	HSD17B10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B10	0.43733205	0.12434861	108	4	FALSE	HSD17B10	HSD17B10	176.6886793	0	107	0	0.78556798	FALSE	1	HSD17B10	736110	0.03988032
787940	taxon:9606	2.2917914	2.59E-04	178536	1902	proliferation-associated 2G4	gene	biological_process-&-1&-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0006417-&&-regulation of translation-%%-GO:0008283-&&-cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006364-&&-rRNA processing-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PA2G4				PA2G4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PA2G4	0.43633989	0.13577852	107	4	FALSE	PA2G4	PA2G4	195.5046729	0	107	0	0.78470143	FALSE	0	PA2G4	547690	0.04442066
788099	taxon:9606	2.33779738	3.70E-04	178241	1902	solute carrier family 25 member 3	gene	biological_process-&-1&-GO:0006839-&&-mitochondrial transport-%%-GO:0035435-&&-phosphate ion transmembrane transport-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015293-&&-symporter activity-%%-GO:0015320-&&-phosphate ion carrier activity-%%-GO:0032403-&&-protein complex binding	G:9606:SLC25A3				SLC25A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A3	0.42775307	0.13330982	107	4	FALSE	SLC25A3	SLC25A3	169.9439252	0	107	0	0.77703377	FALSE	0	SLC25A3	709972	0.04127858
788499	taxon:9606	2.36473925	1.99E-04	177547	1902	small nuclear ribonucleoprotein D3 polypeptide	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008334-&&-histone mRNA metabolic process|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005685-&&-U1 snRNP-%%-GO:0000243-&&-commitment complex-%%-GO:0005686-&&-U2 snRNP-%%-GO:0097526-&&-spliceosomal tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005683-&&-U7 snRNP-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0071209-&&-U7 snRNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990446-&&-U1 snRNP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0071208-&&-histone pre-mRNA DCP binding	G:9606:SNRPD3			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPD3	0.42287961	0.23152883	107	4	FALSE	SNRPD3	SNRPD3	222.5420561	0	107	0	0.77254346	FALSE	0	SNRPD3	513942	0.05633503
788916	taxon:9606	2.38742713	5.50E-04	176601	1902	transgelin 2	gene	biological_process-&-1&-GO:0030855-&&-epithelial cell differentiation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:TAGLN2				TAGLN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAGLN2	0.41886095	0.13472051	107	4	FALSE	TAGLN2	TAGLN2	146.5327103	0	107	0	0.76876214	FALSE	0	TAGLN2	842112	0.03850811
789160	taxon:9606	2.32314479	1.28E-04	176069	1902	squamous cell carcinoma antigen recognized by T-cells 1	gene	biological_process-&-1&-GO:0007050-&&-cell cycle arrest-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000481-&&-maturation of 5S rRNA-%%-GO:0045585-&&-positive regulation of cytotoxic T cell differentiation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005829-&&-cytosol-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SART1			KEGG-&-1&-hsa03040-&&-Spliceosome	SART1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SART1	0.430451	0.27087912	107	4	FALSE	SART1	SART1	220.6190476	0	106	0	0.77947587	FALSE	1	SART1	358136	0.052329
789728	taxon:9606	2.30455333	7.01E-04	174815	1902	programmed cell death 6 interacting protein	gene	biological_process-&-1&-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0090559-&&-regulation of membrane permeability-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0000915-&&-actomyosin contractile ring assembly-%%-GO:0090611-&&-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0015031-&&-protein transport-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0019058-&&-viral life cycle-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006997-&&-nucleus organization-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903551-&&-regulation of extracellular exosome assembly-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0045199-&&-maintenance of epithelial cell apical/basal polarity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0001772-&&-immunological synapse-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005829-&&-cytosol-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0042641-&&-actomyosin-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0031871-&&-proteinase activated receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PDCD6IP			KEGG-&-1&-hsa04144-&&-Endocytosis	PDCD6IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD6IP	0.43392357	0.07527473	107	4	FALSE	PDCD6IP	PDCD6IP	147.3428571	0	106	0	0.78257444	FALSE	1	PDCD6IP	949550	0.03410622
789769	taxon:9606	2.2503545	3.60E-04	174729	1902	G3BP stress granule assembly factor 1	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006810-&&-transport-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:G3BP1				G3BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-G3BP1	0.44437443	0.13754579	107	4	FALSE	G3BP1	G3BP1	210.8666667	0	106	0	0.79160758	FALSE	1	G3BP1	670404	0.04523656
790154	taxon:9606	2.46069009	3.61E-04	173755	1902	ninein like	gene	biological_process-&-1&-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NINL				NINL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NINL	0.40639006	0.07035796	107	4	FALSE	NINL	NINL	91.54205607	0	107	0	0.75655165	FALSE	0	NINL	481912	0.02737982
790859	taxon:9606	2.45249724	4.48E-04	170874	1902	TERF2 interacting protein	gene	biological_process-&-1&-GO:1901985-&&-positive regulation of protein acetylation-%%-GO:0032205-&&-negative regulation of telomere maintenance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0048239-&&-negative regulation of DNA recombination at telomere-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000723-&&-telomere maintenance-%%-GO:0016233-&&-telomere capping-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0070187-&&-shelterin complex-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0030870-&&-Mre11 complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042162-&&-telomeric DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding	G:9606:TERF2IP				TERF2IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERF2IP	0.40774766	0.06410256	107	4	FALSE	TERF2IP	TERF2IP	113.7428571	0	106	0	0.75791713	FALSE	1	TERF2IP	634494	0.03344825
793075	taxon:9606	2.25854735	4.16E-04	180801	1902	general transcription factor IIi	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0014886-&&-transition between slow and fast fiber-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0016525-&&-negative regulation of angiogenesis|cellular_component-&-1&-GO:0042995-&&-cell projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:GTF2I			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors-%%-hsa04022-&&-cGMP-PKG signaling pathway	GTF2I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2I	0.44276247	0.12124542	107	4	FALSE	GTF2I	GTF2I	221.2666667	0	106	0	0.79024211	FALSE	1	GTF2I	820202	0.04790571
787235	taxon:9606	2.37041122	9.01E-04	179823	1902	insulin receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0008544-&&-epidermis development-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0031017-&&-exocrine pancreas development-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0030238-&&-male sex determination-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:2000194-&&-regulation of female gonad development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0008584-&&-male gonad development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0030325-&&-adrenal gland development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0019087-&&-transformation of host cell by virus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0051446-&&-positive regulation of meiotic cell cycle-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0060267-&&-positive regulation of respiratory burst|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005899-&&-insulin receptor complex-%%-GO:0043235-&&-receptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0051425-&&-PTB domain binding-%%-GO:0043559-&&-insulin binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005009-&&-insulin-activated receptor activity-%%-GO:0031994-&&-insulin-like growth factor I binding	G:9606:INSR	INSR	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	INSR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSR	0.42186773	0.10156833	106	4	FALSE	INSR	INSR	107.5673077	0	105	0	0.77159813	FALSE	1	INSR	899016	0.02757396
787624	taxon:9606	2.35134709	1.16E-04	179071	1902	NOP2 nucleolar protein	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0070475-&&-rRNA base methylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000470-&&-maturation of LSU-rRNA|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0009383-&&-rRNA (cytosine-C5-)-methyltransferase activity	G:9606:NOP2				NOP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP2	0.42528813	0.29739443	106	4	FALSE	NOP2	NOP2	214.1509434	0	106	0	0.77477548	FALSE	0	NOP2	300898	0.05299221
787742	taxon:9606	2.282023	1.27E-04	162465	1902	heterogeneous nuclear ribonucleoprotein A3	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:1990124-&&-messenger ribonucleoprotein complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0051033-&&-RNA transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:HNRNPA3			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA3	0.43820768	0.26019766	106	4	FALSE	HNRNPA3	HNRNPA3	254.3962264	0	106	0	0.7863295	FALSE	0	HNRNPA3	402074	0.05701395
787808	taxon:9606	2.32015125	6.49E-04	178757	1902	protein kinase C beta	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035408-&&-histone H3-T6 phosphorylation-%%-GO:0006816-&&-calcium ion transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0071322-&&-cellular response to carbohydrate stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0010829-&&-negative regulation of glucose transport-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042113-&&-B cell activation-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0002250-&&-adaptive immune response-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0035403-&&-histone kinase activity (H3-T6 specific)-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKCB	PRKCB	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04970-&&-Salivary secretion	PRKCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCB	0.43100638	0.07617625	106	4	FALSE	PRKCB	PRKCB	142.2980769	0	105	0	0.77997479	FALSE	1	PRKCB	988644	0.0337017
788428	taxon:9606	2.30817709	1.42E-04	177690	1902	serine and arginine rich splicing factor 3	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:1990825-&&-sequence-specific mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF3			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF3	0.43324232	0.23539982	106	4	FALSE	SRSF3	SRSF3	219.3584906	0	106	0	0.78197048	FALSE	0	SRSF3	385774	0.05103515
788465	taxon:9606	2.37403498	2.51E-04	177584	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007286-&&-spermatid development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0042393-&&-histone binding-%%-GO:0004386-&&-helicase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:SMARCA2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA2	0.42122379	0.19101527	106	4	FALSE	SMARCA2	SMARCA2	172.2264151	0	106	0	0.77099417	FALSE	0	SMARCA2	539266	0.04421489
789216	taxon:9606	2.33574917	4.23E-04	175977	1902	protein inhibitor of activated STAT 1	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0065004-&&-protein-DNA complex assembly-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:PIAS1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05160-&&-Hepatitis C	PIAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS1	0.42812816	0.10474235	106	4	FALSE	PIAS1	PIAS1	133.7788462	0	105	0	0.77737514	FALSE	1	PIAS1	642844	0.03237164
790029	taxon:9606	2.3018749	6.12E-04	174056	1902	nudix hydrolase 21	gene	biological_process-&-1&-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006397-&&-mRNA processing-%%-GO:0051262-&&-protein tetramerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0042382-&&-paraspeckles-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0003723-&&-RNA binding	G:9606:NUDT21			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	NUDT21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDT21	0.43442847	0.09970127	106	4	FALSE	NUDT21	NUDT21	197.4038462	0	105	0	0.78302085	FALSE	1	NUDT21	920832	0.04549686
790569	taxon:9606	2.50953206	3.60E-04	172108	1902	forkhead box B1	gene	biological_process-&-1&-GO:0007595-&&-lactation-%%-GO:0061381-&&-cell migration in diencephalon-%%-GO:0033504-&&-floor plate development-%%-GO:0001756-&&-somitogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0008542-&&-visual learning-%%-GO:0022029-&&-telencephalon cell migration-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0061379-&&-inferior colliculus development-%%-GO:0021794-&&-thalamus development-%%-GO:0021510-&&-spinal cord development-%%-GO:0001655-&&-urogenital system development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061377-&&-mammary gland lobule development-%%-GO:0007412-&&-axon target recognition-%%-GO:0021855-&&-hypothalamus cell migration-%%-GO:0030901-&&-midbrain development-%%-GO:0061374-&&-mammillothalamic axonal tract development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0021767-&&-mammillary body development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FOXB1				FOXB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXB1	0.39848066	0.03647799	106	4	FALSE	FOXB1	FOXB1	84.16037736	0	106	0	0.74841132	FALSE	0	FOXB1	502424	0.02779878
791064	taxon:9606	2.49046794	1.87E-04	170177	1902	PIN2/TERF1 interacting, telomerase inhibitor 1	gene	biological_process-&-1&-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:1902570-&&-protein localization to nucleolus-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0051972-&&-regulation of telomerase activity-%%-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:1904744-&&-positive regulation of telomeric DNA binding-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005819-&&-spindle-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0010521-&&-telomerase inhibitor activity-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PINX1				PINX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PINX1	0.40153097	0.1083558	106	4	FALSE	PINX1	PINX1	136.5283019	0	106	0	0.75158868	FALSE	0	PINX1	415614	0.04324373
792288	taxon:9606	2.39751063	3.84E-04	182280	1902	cyclin dependent kinase 8	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:CDK8				CDK8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK8	0.4170993	0.14115011	106	4	FALSE	CDK8	CDK8	121.4230769	0	105	0	0.76708156	FALSE	1	CDK8	547390	0.03231496
787825	taxon:9606	2.26910351	6.80E-04	178746	1902	protein kinase C zeta	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:2000553-&&-positive regulation of T-helper 2 cell cytokine production-%%-GO:2000664-&&-positive regulation of interleukin-5 secretion-%%-GO:0007616-&&-long-term memory-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051899-&&-membrane depolarization-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0016477-&&-cell migration-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:1990138-&&-neuron projection extension-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:2001181-&&-positive regulation of interleukin-10 secretion-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000667-&&-positive regulation of interleukin-13 secretion-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0070528-&&-protein kinase C signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043203-&&-axon hillock-%%-GO:0045179-&&-apical cortex-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031252-&&-cell leading edge-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005911-&&-cell-cell junction-%%-GO:0045121-&&-membrane raft-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0031941-&&-filamentous actin-%%-GO:0016020-&&-membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0030054-&&-cell junction-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0043274-&&-phospholipase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0043560-&&-insulin receptor substrate binding	G:9606:PRKCZ	PRKCZ	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa04360-&&-Axon guidance-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04611-&&-Platelet activation	PRKCZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCZ	0.44070268	0.09956215	105	4	FALSE	PRKCZ	PRKCZ	143.1359223	0	104	0	0.78848275	FALSE	1	PRKCZ	868218	0.03148399
788161	taxon:9606	2.35371041	5.16E-04	178146	1902	RAB5C, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0015031-&&-protein transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0048227-&&-plasma membrane to endosome transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0031901-&&-early endosome membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding	G:9606:RAB5C			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis	RAB5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB5C	0.4248611	0.10384615	105	4	FALSE	RAB5C	RAB5C	141.9142857	0	105	0	0.7743816	FALSE	0	RAB5C	752424	0.03544484
788943	taxon:9606	2.24310698	3.27E-04	176552	1902	insulin receptor substrate 4	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0008286-&&-insulin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:IRS4	IRS4	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	IRS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRS4	0.44581021	0.10565391	105	4	FALSE	IRS4	IRS4	188.038835	0	104	0	0.7928155	FALSE	1	IRS4	700580	0.03992332
789024	taxon:9606	2.34725067	3.77E-04	176349	1902	ubiquitin specific peptidase 11	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP11				USP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP11	0.42603034	0.06510565	105	4	FALSE	USP11	USP11	130.9126214	0	104	0	0.77545822	FALSE	1	USP11	561690	0.03221905
789513	taxon:9606	2.41720498	4.18E-04	175296	1902	centrosomal protein 57	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0007286-&&-spermatid development-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:CEP57				CEP57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP57	0.41370095	0.06813187	105	4	FALSE	CEP57	CEP57	137.6857143	0	105	0	0.76379917	FALSE	0	CEP57	603652	0.03816134
789644	taxon:9606	2.2886403	3.33E-04	174987	1902	tubulin alpha 1b	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0051301-&&-cell division-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0071353-&&-cellular response to interleukin-4|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005198-&&-structural molecule activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:TUBA1B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome-%%-hsa04210-&&-Apoptosis-%%-hsa04530-&&-Tight junction	TUBA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA1B	0.43694066	0.10714286	105	4	FALSE	TUBA1B	TUBA1B	179.9809524	0	105	0	0.78522662	FALSE	0	TUBA1B	649402	0.04068286
789968	taxon:9606	2.44808571	1.97E-04	174217	1902	chromobox 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048511-&&-rhythmic process-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0035985-&&-senescence-associated heterochromatin focus-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005819-&&-spindle-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:CBX3				CBX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX3	0.40848243	0.23853036	105	4	FALSE	CBX3	CBX3	188.184466	0	104	0	0.75865238	FALSE	1	CBX3	467990	0.05465712
789976	taxon:9606	2.37135655	5.22E-04	174207	1902	GABA type A receptor associated protein like 2	gene	biological_process-&-1&-GO:0006914-&&-autophagy-%%-GO:0061024-&&-membrane organization-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0050811-&&-GABA receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0000149-&&-SNARE binding	G:9606:GABARAPL2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	GABARAPL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAPL2	0.42169955	0.06813187	105	4	FALSE	GABARAPL2	GABARAPL2	98.80952381	0	105	0	0.77144058	FALSE	0	GABARAPL2	634156	0.02534389
790179	taxon:9606	2.43563888	3.46E-04	173704	1902	TRAF2 and NCK interacting kinase	gene	biological_process-&-1&-GO:0007256-&&-activation of JNKK activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030033-&&-microvillus assembly-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0048814-&&-regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0055037-&&-recycling endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:TNIK				TNIK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNIK	0.41056989	0.03160099	105	4	FALSE	TNIK	TNIK	93.66990291	0	104	0	0.76072685	FALSE	1	TNIK	467472	0.02674902
793351	taxon:9606	2.30707421	7.11E-04	180254	1902	nuclear receptor subfamily 4 group A member 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0061469-&&-regulation of type B pancreatic cell proliferation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0071376-&&-cellular response to corticotropin-releasing hormone stimulus-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NR4A1	NR4A1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	NR4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR4A1	0.43344943	0.07443366	105	4	FALSE	NR4A1	NR4A1	131.9708738	0	104	0	0.7821543	FALSE	1	NR4A1	786272	0.03064729
787208	taxon:9606	2.24799118	3.82E-04	179866	1902	microtubule associated protein tau	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:1902474-&&-positive regulation of protein localization to synapse-%%-GO:0098930-&&-axonal transport-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0072386-&&-plus-end-directed organelle transport along microtubule-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0001774-&&-microglial cell activation-%%-GO:0048143-&&-astrocyte activation-%%-GO:0031113-&&-regulation of microtubule polymerization-%%-GO:1905689-&&-positive regulation of diacylglycerol kinase activity-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0031175-&&-neuron projection development-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0050808-&&-synapse organization-%%-GO:1902988-&&-neurofibrillary tangle assembly-%%-GO:0034605-&&-cellular response to heat-%%-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0048699-&&-generation of neurons-%%-GO:0051259-&&-protein oligomerization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:0090258-&&-negative regulation of mitochondrial fission-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0007613-&&-memory-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0048312-&&-intracellular distribution of mitochondria|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0030425-&&-dendrite-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005874-&&-microtubule-%%-GO:0016020-&&-membrane-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0036477-&&-somatodendritic compartment-%%-GO:0016607-&&-nuclear speck-%%-GO:0045298-&&-tubulin complex-%%-GO:0005875-&&-microtubule associated complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0044297-&&-cell body-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0071813-&&-lipoprotein particle binding-%%-GO:0003779-&&-actin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0048018-&&-receptor agonist activity-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0003677-&&-DNA binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:MAPT			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04010-&&-MAPK signaling pathway	MAPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPT	0.4448416	0.11706465	104	4	FALSE	MAPT	MAPT	171.1764706	0	103	0	0.79200147	FALSE	1	MAPT	657504	0.03655845
787214	taxon:9606	2.35780684	3.80E-04	179855	1902	MYC associated factor X	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048678-&&-response to axon injury-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0032868-&&-response to insulin-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0032403-&&-protein complex binding	G:9606:MAX			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	MAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAX	0.42412295	0.07086003	104	4	FALSE	MAX	MAX	133.4019608	0	103	0	0.77369886	FALSE	1	MAX	588594	0.0333157
787411	taxon:9606	2.35749173	4.02E-04	179479	1902	nuclear cap binding protein subunit 1	gene	biological_process-&-1&-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900363-&&-regulation of mRNA polyadenylation-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0010467-&&-gene expression-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0051168-&&-nuclear export-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0008334-&&-histone mRNA metabolic process|cellular_component-&-1&-GO:0005846-&&-nuclear cap binding complex-%%-GO:0034518-&&-RNA cap binding complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0003723-&&-RNA binding	G:9606:NCBP1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	NCBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCBP1	0.42417964	0.1178118	104	4	FALSE	NCBP1	NCBP1	176.8173077	0	104	0	0.77375138	FALSE	0	NCBP1	615102	0.04426496
788567	taxon:9606	2.39057823	2.75E-04	177422	1902	transcriptional adaptor 2A	gene	biological_process-&-1&-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0000125-&&-PCAF complex|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:TADA2A				TADA2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TADA2A	0.41830884	0.106236	104	4	FALSE	TADA2A	TADA2A	129.8846154	0	104	0	0.76823696	FALSE	0	TADA2A	460630	0.03409825
788715	taxon:9606	2.24972428	5.37E-04	177134	1902	tropomyosin 3	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding	G:9606:TPM3			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM3	0.44449891	0.10483401	104	4	FALSE	TPM3	TPM3	180.5196078	0	103	0	0.79171262	FALSE	1	TPM3	812888	0.03863442
788759	taxon:9606	2.36647235	7.44E-04	176998	1902	zinc finger and BTB domain containing 16	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0001823-&&-mesonephros development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0051216-&&-cartilage development-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007417-&&-central nervous system development-%%-GO:0035136-&&-forelimb morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048133-&&-male germ-line stem cell asymmetric division-%%-GO:0051138-&&-positive regulation of NK T cell differentiation|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0001206-&&-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ZBTB16			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	ZBTB16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB16	0.42256991	0.09240924	104	4	FALSE	ZBTB16	ZBTB16	136.1764706	0	103	0	0.77225461	FALSE	1	ZBTB16	886140	0.03454016
788806	taxon:9606	2.238853	4.72E-04	176836	1902	thioredoxin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0030091-&&-protein repair-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0006662-&&-glycerol ether metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0009314-&&-response to radiation-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033158-&&-regulation of protein import into nucleus, translocation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0047134-&&-protein-disulfide reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004791-&&-thioredoxin-disulfide reductase activity-%%-GO:0016671-&&-oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor-%%-GO:0003723-&&-RNA binding-%%-GO:0015037-&&-peptide disulfide oxidoreductase activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:TXN			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway	TXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXN	0.44665728	0.10679612	104	4	FALSE	TXN	TXN	186.0576923	0	104	0	0.7935245	FALSE	0	TXN	825650	0.0392838
789660	taxon:9606	2.32944698	4.65E-04	174954	1902	Yes associated protein 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0003143-&&-embryonic heart tube morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0048368-&&-lateral mesoderm development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1902459-&&-positive regulation of stem cell population maintenance-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0060242-&&-contact inhibition-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0030903-&&-notochord development-%%-GO:0072307-&&-regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:0035329-&&-hippo signaling-%%-GO:0046622-&&-positive regulation of organ growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0003682-&&-chromatin binding	G:9606:YAP1	YAP1	TRUE	KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	YAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YAP1	0.42928644	0.08644511	104	4	FALSE	YAP1	YAP1	132.2403846	0	104	0	0.7784255	FALSE	0	YAP1	658556	0.03167272
789810	taxon:9606	2.44052308	2.42E-04	174605	1902	Sin3A associated protein 18	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0061574-&&-ASAP complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003723-&&-RNA binding	G:9606:SAP18			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	SAP18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAP18	0.40974822	0.13946975	104	4	FALSE	SAP18	SAP18	129.7884615	0	104	0	0.75991282	FALSE	0	SAP18	377638	0.03728448
791307	taxon:9606	2.42650071	1.94E-04	169262	1902	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	gene	biological_process-&-1&-GO:0051304-&&-chromosome separation-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0009117-&&-nucleotide metabolic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006325-&&-chromatin organization|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004386-&&-helicase activity	G:9606:SMARCAD1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SMARCAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCAD1	0.4121161	0.12322629	104	4	FALSE	SMARCAD1	SMARCAD1	141.0096154	0	104	0	0.76224988	FALSE	0	SMARCAD1	339764	0.0394048
792593	taxon:9606	2.33259808	3.17E-04	181750	1902	desmoplakin	gene	biological_process-&-1&-GO:0071896-&&-protein localization to adherens junction-%%-GO:0031424-&&-keratinization-%%-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0002934-&&-desmosome organization-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0034332-&&-adherens junction organization-%%-GO:0042060-&&-wound healing-%%-GO:0070268-&&-cornification-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0008544-&&-epidermis development|cellular_component-&-1&-GO:0005882-&&-intermediate filament-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0001533-&&-cornified envelope-%%-GO:0014704-&&-intercalated disc-%%-GO:0030057-&&-desmosome-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016323-&&-basolateral plasma membrane|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	G:9606:DSP			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	DSP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSP	0.42870652	0.10347505	104	4	FALSE	DSP	DSP	214.8529412	0	103	0	0.77790032	FALSE	1	DSP	756186	0.05183729
787891	taxon:9606	2.3631637	1.73E-04	178649	1902	proteasome 26S subunit, ATPase 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045899-&&-positive regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001824-&&-blastocyst development-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005634-&&-nucleus-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0016234-&&-inclusion body-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0036402-&&-proteasome-activating ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PSMC4			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC4	0.42316154	0.2832667	103	4	FALSE	PSMC4	PSMC4	166.8349515	0	103	0	0.77280605	FALSE	0	PSMC4	392956	0.04208508
788051	taxon:9606	2.35449819	2.50E-04	161922	1902	casein kinase 2 alpha 3	gene		G:9606:CSNK2A3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A3	0.42471895	0.07728917	103	4	FALSE	CSNK2A3	CSNK2A3	140.3883495	0	103	0	0.7742503	FALSE	0	CSNK2A3	476648	0.03500619
788468	taxon:9606	2.28375611	3.22E-04	177581	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:1902661-&&-positive regulation of glucose mediated signaling pathway-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:0006281-&&-DNA repair-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0039692-&&-single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0015074-&&-DNA integration-%%-GO:1900110-&&-negative regulation of histone H3-K9 dimethylation-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007399-&&-nervous system development-%%-GO:2000618-&&-regulation of histone H4-K16 acetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0071564-&&-npBAF complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0002039-&&-p53 binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:SMARCB1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCB1	0.43787513	0.14019802	103	4	FALSE	SMARCB1	SMARCB1	161.5643564	0	102	0	0.78604065	FALSE	1	SMARCB1	608796	0.03618608
788681	taxon:9606	2.3102253	5.44E-04	177204	1902	talin 1	gene	biological_process-&-1&-GO:0070527-&&-platelet aggregation-%%-GO:0016032-&&-viral process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006936-&&-muscle contraction-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0030274-&&-LIM domain binding-%%-GO:0005178-&&-integrin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:TLN1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation	TLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLN1	0.43285821	0.11783743	103	4	FALSE	TLN1	TLN1	175.2621359	0	103	0	0.78162912	FALSE	0	TLN1	786640	0.04093549
788859	taxon:9606	2.35323775	3.31E-04	176741	1902	voltage dependent anion channel 2	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0032272-&&-negative regulation of protein polymerization-%%-GO:0006820-&&-anion transport-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:1903959-&&-regulation of anion transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex|molecular_function-&-1&-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0015288-&&-porin activity-%%-GO:0000166-&&-nucleotide binding	G:9606:VDAC2			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05016-&&-Huntington disease-%%-hsa04217-&&-Necroptosis-%%-hsa04216-&&-Ferroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC2	0.42494644	0.14315629	103	4	FALSE	VDAC2	VDAC2	141.8932039	0	103	0	0.77446037	FALSE	0	VDAC2	588532	0.03533197
789175	taxon:9606	2.38979045	2.40E-04	176045	1902	histone cluster 2 H2A family member c	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2AC			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST2H2AC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2AC	0.41844673	0.27489054	103	4	FALSE	HIST2H2AC	HIST2H2AC	189.815534	0	103	0	0.76836826	FALSE	0	HIST2H2AC	505918	0.0499489
789208	taxon:9606	2.47644556	2.12E-04	175996	1902	chromobox 4	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032183-&&-SUMO binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0035064-&&-methylated histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0016874-&&-ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0051219-&&-phosphoprotein binding	G:9606:CBX4				CBX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX4	0.40380456	0.18237624	103	4	FALSE	CBX4	CBX4	172.2178218	0	102	0	0.75392574	FALSE	1	CBX4	464428	0.05285493
789932	taxon:9606	2.3001418	5.17E-04	174321	1902	prostaglandin E synthase 3	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:1905323-&&-telomerase holoenzyme complex assembly-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0007165-&&-signal transduction-%%-GO:0000723-&&-telomere maintenance-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003720-&&-telomerase activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0050220-&&-prostaglandin-E synthase activity	G:9606:PTGES3			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	PTGES3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGES3	0.43475581	0.08138614	103	4	FALSE	PTGES3	PTGES3	143.6732673	0	102	0	0.7833097	FALSE	1	PTGES3	742924	0.03296089
789934	taxon:9606	2.41169056	5.46E-04	174322	1902	nuclear distribution C, dynein complex regulator	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation-%%-GO:0006457-&&-protein folding-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:NUDC				NUDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDC	0.41464689	0.04644965	103	4	FALSE	NUDC	NUDC	116.368932	0	103	0	0.76471824	FALSE	0	NUDC	712850	0.03194514
790492	taxon:9606	2.29068851	2.42E-04	172707	1902	SUMO1/sentrin/SMT3 specific peptidase 3	gene	biological_process-&-1&-GO:0016926-&&-protein desumoylation-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0016929-&&-SUMO-specific protease activity	G:9606:SENP3				SENP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SENP3	0.43654997	0.10508281	103	4	FALSE	SENP3	SENP3	171.6893204	0	103	0	0.78488525	FALSE	0	SENP3	485678	0.03885912
792285	taxon:9606	2.24657318	7.76E-04	182284	1902	cyclin dependent kinase 5	gene	biological_process-&-1&-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0051301-&&-cell division-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0022038-&&-corpus callosum development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0030182-&&-neuron differentiation-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0001764-&&-neuron migration-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0043113-&&-receptor clustering-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031914-&&-negative regulation of synaptic plasticity-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0033136-&&-serine phosphorylation of STAT3 protein-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0048511-&&-rhythmic process-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0070509-&&-calcium ion import-%%-GO:0008283-&&-cell proliferation-%%-GO:0008542-&&-visual learning-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0016310-&&-phosphorylation-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:1903421-&&-regulation of synaptic vesicle recycling-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0001963-&&-synaptic transmission, dopaminergic-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0021766-&&-hippocampus development-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007416-&&-synapse assembly-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0014044-&&-Schwann cell development-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0031175-&&-neuron projection development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0009611-&&-response to wounding-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0048675-&&-axon extension|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0030175-&&-filopodium-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030027-&&-lamellipodium-%%-GO:0016020-&&-membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0043204-&&-perikaryon-%%-GO:0016533-&&-cyclin-dependent protein kinase 5 holoenzyme complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0030426-&&-growth cone-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005176-&&-ErbB-2 class receptor binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0030549-&&-acetylcholine receptor activator activity-%%-GO:0016301-&&-kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:CDK5	CDK5	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05010-&&-Alzheimer disease-%%-hsa05030-&&-Cocaine addiction	CDK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK5	0.44512238	0.07742574	103	4	FALSE	CDK5	CDK5	142.6831683	0	102	0	0.7922378	FALSE	1	CDK5	914600	0.0303906
792420	taxon:9606	2.35449819	2.50E-04	182049	1902	casein kinase 2 alpha 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006915-&&-apoptotic process-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0071174-&&-mitotic spindle checkpoint-%%-GO:0048511-&&-rhythmic process-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016581-&&-NuRD complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity	G:9606:CSNK2A1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04520-&&-Adherens junction-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway	CSNK2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK2A1	0.42471895	0.07728917	103	4	FALSE	CSNK2A1	CSNK2A1	140.3883495	0	103	0	0.7742503	FALSE	0	CSNK2A1	476648	0.03500619
792808	taxon:9606	2.28990074	1.92E-04	181338	1902	ELAV like RNA binding protein 1	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:1990904-&&-ribonucleoprotein complex|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ELAVL1			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway	ELAVL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELAVL1	0.43670015	0.16415842	103	4	FALSE	ELAVL1	ELAVL1	235.9405941	0	102	0	0.78501654	FALSE	1	ELAVL1	477088	0.05336591
792817	taxon:9606	2.2952576	3.49E-04	181317	1902	cortactin	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0097062-&&-dendritic spine maintenance-%%-GO:0048870-&&-cell motility-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0097581-&&-lamellipodium organization-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0030041-&&-actin filament polymerization-%%-GO:1903146-&&-regulation of mitophagy|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005884-&&-actin filament-%%-GO:0005938-&&-cell cortex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0001726-&&-ruffle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone-%%-GO:0002102-&&-podosome-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005522-&&-profilin binding-%%-GO:0045296-&&-cadherin binding	G:9606:CTTN			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	CTTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTTN	0.43568094	0.10970297	103	4	FALSE	CTTN	CTTN	169.3366337	0	102	0	0.78412373	FALSE	1	CTTN	634590	0.03861273
792964	taxon:9606	2.29620293	7.95E-04	181079	1902	four and a half LIM domains 2	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0055014-&&-atrial cardiac muscle cell development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:FHL2			KEGG-&-1&-hsa04380-&&-Osteoclast differentiation	FHL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHL2	0.43550158	0.06752475	103	4	FALSE	FHL2	FHL2	127.6237624	0	102	0	0.78396618	FALSE	1	FHL2	877818	0.02917507
793046	taxon:9606	2.27083662	9.25E-04	180840	1902	protein disulfide isomerase family A member 3	gene	biological_process-&-1&-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006621-&&-protein retention in ER lumen-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0034975-&&-protein folding in endoplasmic reticulum|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0009986-&&-cell surface-%%-GO:0045335-&&-phagocytic vesicle|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0004629-&&-phospholipase C activity	G:9606:PDIA3			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	PDIA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA3	0.44036634	0.09765848	103	4	FALSE	PDIA3	PDIA3	160.9805825	0	103	0	0.7881939	FALSE	0	PDIA3	1082686	0.03553368
787266	taxon:9606	2.28895541	3.89E-04	179776	1902	junction plakoglobin	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0071603-&&-endothelial cell-cell adhesion-%%-GO:0034333-&&-adherens junction assembly-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0002159-&&-desmosome assembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:0031424-&&-keratinization-%%-GO:0016477-&&-cell migration-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0034332-&&-adherens junction organization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0030056-&&-hemidesmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030057-&&-desmosome-%%-GO:0030018-&&-Z disc-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005911-&&-cell-cell junction-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005915-&&-zonula adherens-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005882-&&-intermediate filament-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0071665-&&-gamma-catenin-TCF7L2 complex-%%-GO:0001533-&&-cornified envelope-%%-GO:0005856-&&-cytoskeleton-%%-GO:0014704-&&-intercalated disc-%%-GO:0016342-&&-catenin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005199-&&-structural constituent of cell wall-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:JUP			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05226-&&-Gastric cancer	JUP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUP	0.43688051	0.1125995	102	4	FALSE	JUP	JUP	175.5294118	0	102	0	0.7851741	FALSE	0	JUP	696236	0.03966998
787416	taxon:9606	2.48826217	6.57E-04	179469	1902	NDUFA4, mitochondrial complex associated	gene	biological_process-&-1&-GO:0006123-&&-mitochondrial electron transport, cytochrome c to oxygen-%%-GO:1902600-&&-hydrogen ion transmembrane transport-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005751-&&-mitochondrial respiratory chain complex IV-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding-%%-GO:0004129-&&-cytochrome-c oxidase activity	G:9606:NDUFA4			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA4	0.40188691	0.08727273	102	4	FALSE	NDUFA4	NDUFA4	86.09	0	101	0	0.7519563	FALSE	1	NDUFA4	801576	0.02706549
788066	taxon:9606	2.44099575	7.75E-05	178288	1902	ribosomal protein L26	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL26			KEGG-&-1&-hsa03010-&&-Ribosome	RPL26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL26	0.40966888	0.40264026	102	4	FALSE	RPL26	RPL26	216.6568628	0	102	0	0.75983404	FALSE	0	RPL26	256914	0.06211212
788191	taxon:9606	2.30486844	5.23E-04	178106	1902	RAS p21 protein activator 1	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0051252-&&-regulation of RNA metabolic process-%%-GO:0009790-&&-embryo development-%%-GO:0007165-&&-signal transduction-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031235-&&-intrinsic component of the cytoplasmic side of the plasma membrane-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0019870-&&-potassium channel inhibitor activity	G:9606:RASA1	RASA1	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	RASA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASA1	0.43386424	0.10868687	102	4	FALSE	RASA1	RASA1	134.69	0	101	0	0.78252193	FALSE	1	RASA1	711854	0.03121289
788403	taxon:9606	2.34977155	8.12E-04	177732	1902	serine/threonine kinase 11	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0001944-&&-vasculature development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0030154-&&-cell differentiation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0051055-&&-negative regulation of lipid biosynthetic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:1904262-&&-negative regulation of TORC1 signaling-%%-GO:0006914-&&-autophagy-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007409-&&-axonogenesis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0007399-&&-nervous system development-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0036399-&&-TCR signalosome assembly-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043276-&&-anoikis-%%-GO:0051645-&&-Golgi localization-%%-GO:0097484-&&-dendrite extension-%%-GO:0045059-&&-positive thymic T cell selection|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0036398-&&-TCR signalosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0002039-&&-p53 binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0030275-&&-LRR domain binding	G:9606:STK11	STK11	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	STK11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK11	0.42557329	0.04707071	102	4	FALSE	STK11	STK11	108.26	0	101	0	0.77503808	FALSE	1	STK11	808674	0.02682878
790611	taxon:9606	2.43059713	4.83E-04	171761	1902	fizzy and cell division cycle 20 related 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0090344-&&-negative regulation of cell aging-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006281-&&-DNA repair-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0010997-&&-anaphase-promoting complex binding	G:9606:FZR1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	FZR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FZR1	0.41142153	0.08192584	102	4	FALSE	FZR1	FZR1	99.21568627	0	102	0	0.76156714	FALSE	0	FZR1	589214	0.02808383
790707	taxon:9606	2.40932724	1.64E-04	171418	1902	transformer 2 alpha homolog	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:TRA2A			KEGG-&-1&-hsa03040-&&-Spliceosome	TRA2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRA2A	0.41505362	0.17744127	102	4	FALSE	TRA2A	TRA2A	158.3039216	0	102	0	0.76511213	FALSE	0	TRA2A	326560	0.04294469
792396	taxon:9606	2.35969749	7.12E-04	182098	1902	CRK like proto-oncogene, adaptor protein	gene	biological_process-&-1&-GO:0048538-&&-thymus development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007507-&&-heart development-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0060017-&&-parathyroid gland development-%%-GO:0001568-&&-blood vessel development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007254-&&-JNK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:CRKL			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton	CRKL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRKL	0.42378313	0.1125995	102	4	FALSE	CRKL	CRKL	124.9019608	0	102	0	0.77338375	FALSE	0	CRKL	894366	0.03142042
792841	taxon:9606	2.27288483	2.37E-04	181277	1902	glutamyl-prolyl-tRNA synthetase	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006433-&&-prolyl-tRNA aminoacylation-%%-GO:0006424-&&-glutamyl-tRNA aminoacylation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006418-&&-tRNA aminoacylation for protein translation|cellular_component-&-1&-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0097452-&&-GAIT complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004818-&&-glutamate-tRNA ligase activity-%%-GO:0004827-&&-proline-tRNA ligase activity-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:EPRS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism	EPRS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPRS	0.4399695	0.15996894	102	4	FALSE	EPRS	EPRS	213.8921569	0	102	0	0.78785253	FALSE	0	EPRS	516390	0.04726682
788437	taxon:9606	2.32708366	1.47E-04	144907	1902	RBM14-RBM4 readthrough	gene		G:9606:RBM14-RBM4				RBM14-RBM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM14-RBM4	0.42972241	0.18693069	101	4	FALSE	RBM14-RBM4	RBM14-RBM4	222.4653465	0	101	0	0.77881939	FALSE	0	RBM14-RBM4	411050	0.05310467
788474	taxon:9606	2.33448873	5.22E-04	177578	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007399-&&-nervous system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0006337-&&-nucleosome disassembly|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SMARCD1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCD1	0.42835932	0.1419802	101	4	FALSE	SMARCD1	SMARCD1	162.4059406	0	101	0	0.77758521	FALSE	0	SMARCD1	775268	0.03909603
788594	taxon:9606	2.45832677	0.00103499	177373	1902	elongin C	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070449-&&-elongin complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:ELOC			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	ELOC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELOC	0.40678075	0.06217822	101	4	FALSE	ELOC	ELOC	106.9108911	0	101	0	0.75694554	FALSE	0	ELOC	1801474	0.03169786
789255	taxon:9606	2.3812825	2.04E-04	175891	1902	eukaryotic translation initiation factor 3 subunit A	gene	biological_process-&-1&-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0002188-&&-translation reinitiation-%%-GO:0001732-&&-formation of cytoplasmic translation initiation complex|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0005874-&&-microtubule-%%-GO:0043614-&&-multi-eIF complex-%%-GO:0071540-&&-eukaryotic translation initiation factor 3 complex, eIF3e-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0003723-&&-RNA binding	G:9606:EIF3A			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3A	0.41994178	0.16039604	101	4	FALSE	EIF3A	EIF3A	168.3267327	0	101	0	0.76978625	FALSE	0	EIF3A	400208	0.04381079
789667	taxon:9606	2.32708366	1.47E-04	174939	1902	RNA binding motif protein 14	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0016575-&&-histone deacetylation-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0046600-&&-negative regulation of centriole replication-%%-GO:0006260-&&-DNA replication-%%-GO:0009725-&&-response to hormone-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0098534-&&-centriole assembly|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:RBM14				RBM14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM14	0.42972241	0.18693069	101	4	FALSE	RBM14	RBM14	222.4653465	0	101	0	0.77881939	FALSE	0	RBM14	411050	0.05310467
789695	taxon:9606	2.45942965	5.13E-04	174878	1902	nuclear receptor coactivator 2	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1904017-&&-cellular response to Thyroglobulin triiodothyronine-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0032922-&&-circadian regulation of gene expression|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:NCOA2	NCOA2	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	NCOA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA2	0.40659833	0.10183467	101	4	FALSE	NCOA2	NCOA2	130.3333333	0	100	0	0.75676172	FALSE	1	NCOA2	791704	0.03850264
790585	taxon:9606	2.33244052	4.89E-04	172068	1902	calcyclin binding protein	gene	biological_process-&-1&-GO:0060548-&&-negative regulation of cell death-%%-GO:0007568-&&-aging-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0060416-&&-response to growth hormone-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0044297-&&-cell body-%%-GO:0030877-&&-beta-catenin destruction complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CACYBP			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	CACYBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACYBP	0.42873548	0.05833849	101	4	FALSE	CACYBP	CACYBP	131.040404	0	100	0	0.77792658	FALSE	1	CACYBP	689630	0.03153071
793195	taxon:9606	2.41137545	7.14E-04	180545	1902	HRas proto-oncogene, GTPase	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0090398-&&-cellular senescence-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0008283-&&-cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0035900-&&-response to isolation stress-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:1900029-&&-positive regulation of ruffle assembly-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0007411-&&-axon guidance-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0007165-&&-signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0006897-&&-endocytosis-%%-GO:2000630-&&-positive regulation of miRNA metabolic process-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005525-&&-GTP binding	G:9606:HRAS			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05219-&&-Bladder cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04144-&&-Endocytosis-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	HRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HRAS	0.41470108	0.04555762	101	4	FALSE	HRAS	HRAS	90.2020202	0	100	0	0.76477076	FALSE	1	HRAS	759660	0.0247896
787069	taxon:9606	2.39609264	3.82E-04	180122	1902	immunoglobulin binding protein 1	gene	biological_process-&-1&-GO:0060632-&&-regulation of microtubule-based movement-%%-GO:0007165-&&-signal transduction-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042113-&&-B cell activation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0034612-&&-response to tumor necrosis factor|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:IGBP1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04136-&&-Autophagy - other	IGBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGBP1	0.41734613	0.05474747	100	4	FALSE	IGBP1	IGBP1	109.04	0	100	0	0.76731789	FALSE	0	IGBP1	542868	0.0290253
787305	taxon:9606	2.39498976	5.12E-04	179688	1902	kinesin family member 11	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051301-&&-cell division-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007059-&&-chromosome segregation-%%-GO:0007051-&&-spindle organization-%%-GO:0007100-&&-mitotic centrosome separation-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0046602-&&-regulation of mitotic centrosome separation-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed	G:9606:KIF11				KIF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF11	0.41753832	0.08226383	100	4	FALSE	KIF11	KIF11	155.877551	0	99	0	0.76750171	FALSE	1	KIF11	800944	0.04135267
787838	taxon:9606	2.348196	6.13E-04	178735	1902	mitogen-activated protein kinase 9	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0061833-&&-protein localization to tricellular tight junction-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0007254-&&-JNK cascade-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0048666-&&-neuron development-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0009612-&&-response to mechanical stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004705-&&-JUN kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:MAPK9			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05131-&&-Shigellosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK9	0.42585883	0.06921944	100	4	FALSE	MAPK9	MAPK9	113.5612245	0	99	0	0.77530067	FALSE	1	MAPK9	757952	0.02802657
788402	taxon:9606	2.43233023	1.98E-04	161348	1902	histone cluster 2 H3 family member a	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3A	0.41112838	0.05434343	100	4	FALSE	HIST2H3A	HIST2H3A	132.27	0	100	0	0.76127829	FALSE	0	HIST2H3A	542198	0.03751986
790756	taxon:9606	2.43233023	1.98E-04	154932	1902	histone cluster 2 H3 family member d	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3D			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3D	0.41112838	0.05434343	100	4	FALSE	HIST2H3D	HIST2H3D	132.27	0	100	0	0.76127829	FALSE	0	HIST2H3D	542198	0.03751986
791901	taxon:9606	2.46226564	5.64E-04	182910	1902	amino-terminal enhancer of split	gene	biological_process-&-1&-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001501-&&-skeletal system development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0040008-&&-regulation of growth|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:AES				AES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AES	0.40613002	0.06648433	100	4	FALSE	AES	AES	88.40816327	0	99	0	0.75628906	FALSE	1	AES	673362	0.02642439
791926	taxon:9606	2.33858516	4.44E-04	166481	1902	Fas binding factor 1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0043297-&&-apical junction assembly-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0090162-&&-establishment of epithelial cell polarity|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0043296-&&-apical junction complex-%%-GO:0045095-&&-keratin filament-%%-GO:0097539-&&-ciliary transition fiber|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBF1				FBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBF1	0.42760897	0.06525253	100	4	FALSE	FBF1	FBF1	122.45	0	100	0	0.77690247	FALSE	0	FBF1	645660	0.02977864
791978	taxon:9606	2.40097684	3.84E-04	182777	1902	baculoviral IAP repeat containing 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0039535-&&-regulation of RIG-I signaling pathway-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0001890-&&-placenta development-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:1902523-&&-positive regulation of protein K63-linked ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:1902527-&&-positive regulation of protein monoubiquitination-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1902443-&&-negative regulation of ripoptosome assembly involved in necroptotic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0070266-&&-necroptotic process-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0051591-&&-response to cAMP-%%-GO:1902524-&&-positive regulation of protein K48-linked ubiquitination|cellular_component-&-1&-GO:0001741-&&-XY body-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0045121-&&-membrane raft-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0098770-&&-FBXO family protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:BIRC2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	BIRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC2	0.41649715	0.11824111	100	4	FALSE	BIRC2	BIRC2	117.4081633	0	99	0	0.76650386	FALSE	1	BIRC2	522748	0.03148539
792624	taxon:9606	2.49613991	3.45E-04	165318	1902	neural precursor cell expressed, developmentally down-regulated 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0000922-&&-spindle pole-%%-GO:0005814-&&-centriole-%%-GO:0036064-&&-ciliary basal body-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NEDD1				NEDD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD1	0.40061857	0.09010101	100	4	FALSE	NEDD1	NEDD1	112.19	0	100	0	0.75064335	FALSE	0	NEDD1	532882	0.03584586
792754	taxon:9606	2.43233023	1.98E-04	165048	1902	histone cluster 2 H3 family member c	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0007596-&&-blood coagulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding	G:9606:HIST2H3C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism	HIST2H3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H3C	0.41112838	0.05434343	100	4	FALSE	HIST2H3C	HIST2H3C	132.27	0	100	0	0.76127829	FALSE	0	HIST2H3C	542198	0.03751986
792823	taxon:9606	2.39546242	4.33E-04	181301	1902	endothelial PAS domain protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0007165-&&-signal transduction-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0001525-&&-angiogenesis-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0007601-&&-visual perception-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0048625-&&-myoblast fate commitment-%%-GO:0001666-&&-response to hypoxia-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0030324-&&-lung development-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0043129-&&-surfactant homeostasis-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0042415-&&-norepinephrine metabolic process-%%-GO:0048469-&&-cell maturation|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035035-&&-histone acetyltransferase binding	G:9606:EPAS1			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma	EPAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPAS1	0.41745593	0.08836524	100	4	FALSE	EPAS1	EPAS1	120.2142857	0	99	0	0.76742293	FALSE	1	EPAS1	616880	0.03194097
792974	taxon:9606	2.62060816	2.22E-04	181057	1902	forkhead box L1	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development-%%-GO:0030166-&&-proteoglycan biosynthetic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0061146-&&-Peyer's patch morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0007495-&&-visceral mesoderm-endoderm interaction involved in midgut development-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXL1				FOXL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXL1	0.38159081	0.01616162	100	4	FALSE	FOXL1	FOXL1	58.44	0	100	0	0.72989864	FALSE	0	FOXL1	283448	0.02488213
793208	taxon:9606	2.3930991	5.99E-04	180524	1902	heat shock transcription factor 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009299-&&-mRNA transcription-%%-GO:0051028-&&-mRNA transport-%%-GO:0034605-&&-cellular response to heat-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2001033-&&-negative regulation of double-strand break repair via nonhomologous end joining-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:0072738-&&-cellular response to diamide-%%-GO:0006281-&&-DNA repair-%%-GO:1904843-&&-cellular response to nitroglycerin-%%-GO:1990910-&&-response to hypobaric hypoxia-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0007143-&&-female meiotic division-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0033574-&&-response to testosterone-%%-GO:0034620-&&-cellular response to unfolded protein-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0061408-&&-positive regulation of transcription from RNA polymerase II promoter in response to heat stress-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:1902512-&&-positive regulation of apoptotic DNA fragmentation-%%-GO:0006952-&&-defense response-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:1900365-&&-positive regulation of mRNA polyadenylation-%%-GO:1904845-&&-cellular response to L-glutamine-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090261-&&-positive regulation of inclusion body assembly-%%-GO:0006397-&&-mRNA processing-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0014823-&&-response to activity-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1990911-&&-response to psychosocial stress-%%-GO:1904528-&&-positive regulation of microtubule binding-%%-GO:0060136-&&-embryonic process involved in female pregnancy-%%-GO:0007584-&&-response to nutrient|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0045120-&&-pronucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000792-&&-heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097165-&&-nuclear stress granule-%%-GO:0097431-&&-mitotic spindle pole-%%-GO:0000791-&&-euchromatin-%%-GO:0016605-&&-PML body-%%-GO:1990904-&&-ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0097677-&&-STAT family protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0043621-&&-protein self-association-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0098847-&&-sequence-specific single stranded DNA binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0061770-&&-translation elongation factor binding	G:9606:HSF1	HSF1	TRUE	KEGG-&-1&-hsa05134-&&-Legionellosis	HSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSF1	0.41786819	0.06985062	100	4	FALSE	HSF1	HSF1	120.6020408	0	99	0	0.76781682	FALSE	1	HSF1	725870	0.03186921
787307	taxon:9606	2.30770443	3.11E-04	179684	1902	karyopherin subunit alpha 1	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0019054-&&-modulation by virus of host process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:KPNA1			KEGG-&-1&-hsa05164-&&-Influenza A	KPNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA1	0.43333106	0.11193568	99	4	FALSE	KPNA1	KPNA1	176.5454546	0	99	0	0.78204926	FALSE	0	KPNA1	562152	0.04088125
788288	taxon:9606	2.35843706	4.73E-05	177951	1902	ribosomal protein S17	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0006412-&&-translation-%%-GO:0019083-&&-viral transcription-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005840-&&-ribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:RPS17			KEGG-&-1&-hsa03010-&&-Ribosome	RPS17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS17	0.42400962	0.48526077	99	4	FALSE	RPS17	RPS17	255.7171717	0	99	0	0.77359382	FALSE	0	RPS17	216370	0.06391331
788707	taxon:9606	2.33039231	3.58E-04	177144	1902	tumor protein p53 binding protein 2	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0051059-&&-NF-kappaB binding	G:9606:TP53BP2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway	TP53BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53BP2	0.4291123	0.0992268	99	4	FALSE	TP53BP2	TP53BP2	144.3298969	0	98	0	0.77826795	FALSE	1	TP53BP2	610052	0.03453695
788929	taxon:9606	2.45170947	3.52E-04	176577	1902	NCK adaptor protein 2	gene	biological_process-&-1&-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0042110-&&-T cell activation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0007176-&&-regulation of epidermal growth factor-activated receptor activity-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0036493-&&-positive regulation of translation in response to endoplasmic reticulum stress-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007172-&&-signal complex assembly-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0060996-&&-dendritic spine development-%%-GO:0007015-&&-actin filament organization-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0097110-&&-scaffold protein binding	G:9606:NCK2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NCK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCK2	0.40787867	0.05906357	99	4	FALSE	NCK2	NCK2	88.91752577	0	98	0	0.75804842	FALSE	1	NCK2	454336	0.02607285
789643	taxon:9606	2.30266268	5.42E-04	174984	1902	tubulin beta 3 class III	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0030424-&&-axon-%%-GO:0030425-&&-dendrite-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0042277-&&-peptide binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB3			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB3	0.43427985	0.08864152	99	4	FALSE	TUBB3	TUBB3	169.010101	0	99	0	0.78288955	FALSE	0	TUBB3	868396	0.03893743
790023	taxon:9606	2.41878053	2.08E-04	174069	1902	receptor interacting serine/threonine kinase 3	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0002819-&&-regulation of adaptive immune response-%%-GO:0048535-&&-lymph node development-%%-GO:0060545-&&-positive regulation of necroptotic process-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0090312-&&-positive regulation of protein deacetylation-%%-GO:0048538-&&-thymus development-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0001914-&&-regulation of T cell mediated cytotoxicity-%%-GO:0048536-&&-spleen development-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0070266-&&-necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0051351-&&-positive regulation of ligase activity-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:0010922-&&-positive regulation of phosphatase activity-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0046006-&&-regulation of activated T cell proliferation-%%-GO:2000452-&&-regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation-%%-GO:0032649-&&-regulation of interferon-gamma production-%%-GO:0070235-&&-regulation of activation-induced cell death of T cells|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0097342-&&-ripoptosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005524-&&-ATP binding	G:9606:RIPK3			KEGG-&-1&-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	RIPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK3	0.41343147	0.08784364	99	4	FALSE	RIPK3	RIPK3	131.1443299	0	98	0	0.76353658	FALSE	1	RIPK3	357182	0.03623919
790077	taxon:9606	2.34599023	6.76E-04	173928	1902	checkpoint kinase 2	gene	biological_process-&-1&-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:1903926-&&-cellular response to bisphenol A-%%-GO:0001302-&&-replicative cell aging-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0072428-&&-signal transduction involved in intra-S DNA damage checkpoint-%%-GO:1903416-&&-response to glycoside-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0090399-&&-replicative senescence-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CHEK2	CHEK2	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence	CHEK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHEK2	0.42625923	0.06572165	99	4	FALSE	CHEK2	CHEK2	122.3814433	0	98	0	0.77566829	FALSE	1	CHEK2	764898	0.03016946
790481	taxon:9606	2.27146683	1.14E-04	172729	1902	SERPINE1 mRNA binding protein 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:SERBP1				SERBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERBP1	0.44024416	0.20640034	99	4	FALSE	SERBP1	SERBP1	252.8762887	0	98	0	0.78808886	FALSE	1	SERBP1	398672	0.05552839
790498	taxon:9606	2.25003939	2.24E-04	172687	1902	phosphoglycerate dehydrogenase	gene	biological_process-&-1&-GO:0006566-&&-threonine metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006564-&&-L-serine biosynthetic process-%%-GO:0007420-&&-brain development-%%-GO:0009448-&&-gamma-aminobutyric acid metabolic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0021510-&&-spinal cord development-%%-GO:0021915-&&-neural tube development-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0021782-&&-glial cell development-%%-GO:0070314-&&-G1 to G0 transition|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0004617-&&-phosphoglycerate dehydrogenase activity-%%-GO:0051287-&&-NAD binding	G:9606:PHGDH	PHGDH	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	PHGDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHGDH	0.44443666	0.14759843	99	4	FALSE	PHGDH	PHGDH	234.979798	0	99	0	0.7916601	FALSE	0	PHGDH	548982	0.0503061
791154	taxon:9606	2.46510162	1.60E-04	169875	1902	Ly1 antibody reactive	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:LYAR				LYAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYAR	0.40566279	0.16821274	99	4	FALSE	LYAR	LYAR	151.6161616	0	99	0	0.7558164	FALSE	0	LYAR	293462	0.04535783
791381	taxon:9606	2.41421144	8.29E-04	168861	1902	SRP receptor beta subunit	gene	biological_process-&-1&-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005785-&&-signal recognition particle receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0005047-&&-signal recognition particle binding-%%-GO:0005525-&&-GTP binding	G:9606:SRPRB			KEGG-&-1&-hsa03060-&&-Protein export	SRPRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPRB	0.41421393	0.0430839	99	4	FALSE	SRPRB	SRPRB	111.2121212	0	99	0	0.76429809	FALSE	0	SRPRB	965320	0.03052509
791625	taxon:9606	2.65920908	4.12E-04	167753	1902	tectonic family member 2	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0060170-&&-ciliary membrane-%%-GO:0036038-&&-MKS complex	G:9606:TCTN2				TCTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN2	0.37605166	0.03153989	99	4	FALSE	TCTN2	TCTN2	51.09090909	0	99	0	0.72346515	FALSE	0	TCTN2	486664	0.02419913
792406	taxon:9606	2.25760202	3.81E-04	182069	1902	chromosome segregation 1 like	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005049-&&-nuclear export signal receptor activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:CSE1L				CSE1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSE1L	0.44294787	0.12739641	99	4	FALSE	CSE1L	CSE1L	207.5555556	0	99	0	0.79039966	FALSE	0	CSE1L	683500	0.04487469
792689	taxon:9606	2.40617615	4.60E-04	181556	1902	growth arrest and DNA damage inducible alpha	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006281-&&-DNA repair-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007098-&&-centrosome cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding	G:9606:GADD45A			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GADD45A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GADD45A	0.41559717	0.06378866	99	4	FALSE	GADD45A	GADD45A	138.5670103	0	98	0	0.76563731	FALSE	1	GADD45A	686176	0.0375213
787227	taxon:9606	2.42461005	1.14E-04	179834	1902	minichromosome maintenance complex component 4	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM4			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM4	0.41243746	0.24671053	98	4	FALSE	MCM4	MCM4	206.71875	0	97	0	0.76256499	FALSE	1	MCM4	324324	0.05746687
787358	taxon:9606	2.41421144	5.60E-04	179598	1902	melatonin receptor 1A	gene	biological_process-&-1&-GO:0007617-&&-mating behavior-%%-GO:0007623-&&-circadian rhythm-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008502-&&-melatonin receptor activity-%%-GO:0042562-&&-hormone binding-%%-GO:0005515-&&-protein binding-%%-GO:0097159-&&-organic cyclic compound binding	G:9606:MTNR1A	MTNR1A	TRUE	KEGG-&-1&-hsa04713-&&-Circadian entrainment-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	MTNR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTNR1A	0.41421393	0.05460526	98	4	FALSE	MTNR1A	MTNR1A	113.1145833	0	97	0	0.76429809	FALSE	1	MTNR1A	637272	0.03117527
788179	taxon:9606	2.34520246	3.77E-04	178122	1902	Ran GTPase activating protein 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:1904117-&&-cellular response to vasopressin-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0016925-&&-protein sumoylation-%%-GO:0048678-&&-response to axon injury|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0072686-&&-mitotic spindle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:1990723-&&-cytoplasmic periphery of the nuclear pore complex-%%-GO:0016235-&&-aggresome-%%-GO:0044614-&&-nuclear pore cytoplasmic filaments|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0045296-&&-cadherin binding	G:9606:RANGAP1			KEGG-&-1&-hsa03013-&&-RNA transport	RANGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANGAP1	0.42640242	0.10197368	98	4	FALSE	RANGAP1	RANGAP1	153.3125	0	97	0	0.77579959	FALSE	1	RANGAP1	603734	0.03754032
788426	taxon:9606	2.33433118	1.79E-04	177688	1902	serine and arginine rich splicing factor 5	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0009611-&&-response to wounding-%%-GO:0097421-&&-liver regeneration-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0050733-&&-RS domain binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SRSF5			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF5	0.42838823	0.20892068	98	4	FALSE	SRSF5	SRSF5	193.8571429	0	98	0	0.77761147	FALSE	0	SRSF5	365584	0.04668515
788659	taxon:9606	2.28722231	6.49E-04	177237	1902	transglutaminase 2	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0018153-&&-isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0060662-&&-salivary gland cavitation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis|cellular_component-&-1&-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003810-&&-protein-glutamine gamma-glutamyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding	G:9606:TGM2			KEGG-&-1&-hsa05016-&&-Huntington disease	TGM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGM2	0.43721155	0.08640351	98	4	FALSE	TGM2	TGM2	154.7395833	0	97	0	0.78546295	FALSE	1	TGM2	804708	0.03493159
789076	taxon:9606	2.63210966	6.66E-04	159859	1902	keratin associated protein 10-3	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament	G:9606:KRTAP10-3				KRTAP10-3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-3	0.37992338	0.09780702	98	4	FALSE	KRTAP10-3	KRTAP10-3	51.6875	0	97	0	0.72798172	FALSE	1	KRTAP10-3	1052680	0.02267614
789570	taxon:9606	2.3878998	1.92E-04	175156	1902	proteasome 26S subunit, non-ATPase 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0006508-&&-proteolysis-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:PSMD6			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa05169-&&-Epstein-Barr virus infection	PSMD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD6	0.41877804	0.27687776	98	4	FALSE	PSMD6	PSMD6	143.4897959	0	98	0	0.76868337	FALSE	0	PSMD6	347494	0.0375923
789761	taxon:9606	2.25602647	3.04E-04	174745	1902	leucine rich pentatricopeptide repeat containing	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0000961-&&-negative regulation of mitochondrial RNA catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0070129-&&-regulation of mitochondrial translation-%%-GO:0009451-&&-RNA modification-%%-GO:0047497-&&-mitochondrion transport along microtubule|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005874-&&-microtubule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:LRPPRC				LRPPRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRPPRC	0.44325721	0.07390351	98	4	FALSE	LRPPRC	LRPPRC	219.7083333	0	97	0	0.79066226	FALSE	1	LRPPRC	719850	0.04743746
789792	taxon:9606	2.38600914	2.27E-04	174670	1902	proteasome 26S subunit, non-ATPase 14	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061133-&&-endopeptidase activator activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity	G:9606:PSMD14			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD14	0.41910988	0.29013255	98	4	FALSE	PSMD14	PSMD14	133.8979592	0	98	0	0.76899848	FALSE	0	PSMD14	400318	0.03510161
790045	taxon:9606	2.31794549	2.65E-04	174015	1902	heterogeneous nuclear ribonucleoprotein U like 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0006396-&&-RNA processing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPUL1			KEGG-&-1&-hsa05164-&&-Influenza A	HNRNPUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPUL1	0.43141653	0.16666667	98	4	FALSE	HNRNPUL1	HNRNPUL1	210.1979167	0	97	0	0.78034242	FALSE	1	HNRNPUL1	523668	0.04934648
790203	taxon:9606	2.26863085	2.82E-04	173648	1902	TGF-beta activated kinase 1/MAP3K7 binding protein 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TAB2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway	TAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAB2	0.4407945	0.14868421	98	4	FALSE	TAB2	TAB2	181.46875	0	97	0	0.78856153	FALSE	1	TAB2	545796	0.03986572
790475	taxon:9606	2.39404443	2.41E-04	172737	1902	pre-mRNA processing factor 31	gene	biological_process-&-1&-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048254-&&-snoRNA localization-%%-GO:0071166-&&-ribonucleoprotein complex localization|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0071011-&&-precatalytic spliceosome-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0005690-&&-U4atac snRNP-%%-GO:0005687-&&-U4 snRNP|molecular_function-&-1&-GO:0070990-&&-snRNP binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF31			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF31	0.41770319	0.14166667	98	4	FALSE	PRPF31	PRPF31	177.9270833	0	97	0	0.76765926	FALSE	1	PRPF31	613960	0.04700572
791321	taxon:9606	2.35103198	1.87E-04	169179	1902	DEAD-box helicase 24	gene	biological_process-&-1&-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0016070-&&-RNA metabolic process|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003724-&&-RNA helicase activity	G:9606:DDX24				DDX24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX24	0.42534513	0.19100877	98	4	FALSE	DDX24	DDX24	178.3541667	0	97	0	0.774828	FALSE	1	DDX24	381384	0.04392703
792484	taxon:9606	2.48132976	7.02E-04	181944	1902	BCL2 like 1	gene	biological_process-&-1&-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007281-&&-germ cell development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0008283-&&-cell proliferation-%%-GO:0040007-&&-growth-%%-GO:0007283-&&-spermatogenesis-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0009566-&&-fertilization-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0000910-&&-cytokinesis-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060154-&&-cellular process regulating host cell cycle in response to virus-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090005-&&-negative regulation of establishment of protein localization to plasma membrane-%%-GO:0071839-&&-apoptotic process in bone marrow-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0034097-&&-response to cytokine-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0019050-&&-suppression by virus of host apoptotic process-%%-GO:0046898-&&-response to cycloheximide-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1900118-&&-negative regulation of execution phase of apoptosis-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0008584-&&-male gonad development-%%-GO:0006897-&&-endocytosis-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0030054-&&-cell junction-%%-GO:0097136-&&-Bcl-2 family protein complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051434-&&-BH3 domain binding	G:9606:BCL2L1	BCL2L1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma	BCL2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L1	0.40300971	0.05679825	98	4	FALSE	BCL2L1	BCL2L1	76.64583333	0	97	0	0.75311171	FALSE	1	BCL2L1	711038	0.02378963
792605	taxon:9606	2.33354341	5.45E-04	181729	1902	dishevelled segment polarity protein 2	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0034613-&&-cellular protein localization-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0051259-&&-protein oligomerization-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0001843-&&-neural tube closure-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0022007-&&-convergent extension involved in neural plate elongation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035567-&&-non-canonical Wnt signaling pathway-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0044340-&&-canonical Wnt signaling pathway involved in regulation of cell proliferation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0007379-&&-segment specification|cellular_component-&-1&-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016235-&&-aggresome-%%-GO:0005634-&&-nucleus-%%-GO:0045177-&&-apical part of cell-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005109-&&-frizzled binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:DVL2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DVL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DVL2	0.42853285	0.06776316	98	4	FALSE	DVL2	DVL2	131.4375	0	97	0	0.77774277	FALSE	1	DVL2	697024	0.03166426
787018	taxon:9606	2.37419253	7.69E-04	180223	1902	integrin subunit beta 1	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016477-&&-cell migration-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048675-&&-axon extension-%%-GO:0030183-&&-B cell differentiation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0001708-&&-cell fate specification-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0007161-&&-calcium-independent cell-matrix adhesion-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0008542-&&-visual learning-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0031623-&&-receptor internalization-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0008354-&&-germ cell migration-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0050900-&&-leukocyte migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0010710-&&-regulation of collagen catabolic process-%%-GO:0033631-&&-cell-cell adhesion mediated by integrin-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0045214-&&-sarcomere organization-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006968-&&-cellular defense response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0043197-&&-dendritic spine-%%-GO:0032154-&&-cleavage furrow-%%-GO:0034678-&&-integrin alpha8-beta1 complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0032587-&&-ruffle membrane-%%-GO:0034665-&&-integrin alpha1-beta1 complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0043235-&&-receptor complex-%%-GO:0097060-&&-synaptic membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030175-&&-filopodium-%%-GO:0034680-&&-integrin alpha10-beta1 complex-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0034681-&&-integrin alpha11-beta1 complex-%%-GO:0034677-&&-integrin alpha7-beta1 complex-%%-GO:0034666-&&-integrin alpha2-beta1 complex-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0008305-&&-integrin complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0009986-&&-cell surface-%%-GO:0055037-&&-recycling endosome-%%-GO:0016020-&&-membrane-%%-GO:0034667-&&-integrin alpha3-beta1 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042470-&&-melanosome-%%-GO:0071438-&&-invadopodium membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001968-&&-fibronectin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0043236-&&-laminin binding-%%-GO:0019960-&&-C-X3-C chemokine binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003779-&&-actin binding-%%-GO:0098639-&&-collagen binding involved in cell-matrix adhesion-%%-GO:0015026-&&-coreceptor activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:ITGB1			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04145-&&-Phagosome-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa05133-&&-Pertussis-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB1	0.42119583	0.07950728	97	4	FALSE	ITGB1	ITGB1	134.1684211	0	96	0	0.77096791	FALSE	1	ITGB1	941526	0.03454812
787333	taxon:9606	2.48148732	4.60E-04	179652	1902	keratin 31	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:KRT31			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT31	0.40298413	0.02813574	97	4	FALSE	KRT31	KRT31	77.01030928	0	97	0	0.75308545	FALSE	0	KRT31	539804	0.02400985
787793	taxon:9606	2.30738932	5.17E-04	178773	1902	protein kinase AMP-activated catalytic subunit alpha 1	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0031000-&&-response to caffeine-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0009631-&&-cold acclimation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0061762-&&-CAMKK-AMPK signaling cascade-%%-GO:1901563-&&-response to camptothecin-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0071417-&&-cellular response to organonitrogen compound-%%-GO:2001274-&&-negative regulation of glucose import in response to insulin stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0048511-&&-rhythmic process-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation-%%-GO:0045542-&&-positive regulation of cholesterol biosynthetic process-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0009411-&&-response to UV-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0046318-&&-negative regulation of glucosylceramide biosynthetic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0014823-&&-response to activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0070301-&&-cellular response to hydrogen peroxide|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0047322-&&-[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0050405-&&-[acetyl-CoA carboxylase] kinase activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity	G:9606:PRKAA1	PRKAA1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	PRKAA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAA1	0.43339024	0.07109107	97	4	FALSE	PRKAA1	PRKAA1	136.8762887	0	97	0	0.78210178	FALSE	0	PRKAA1	688742	0.0316944
788811	taxon:9606	2.3997164	9.59E-05	176825	1902	U2 small nuclear RNA auxiliary factor 1	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0015030-&&-Cajal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0089701-&&-U2AF|molecular_function-&-1&-GO:0050733-&&-RS domain binding-%%-GO:0030628-&&-pre-mRNA 3'-splice site binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:U2AF1			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa05131-&&-Shigellosis	U2AF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF1	0.41671591	0.26181271	97	4	FALSE	U2AF1	U2AF1	193.4123711	0	97	0	0.76671393	FALSE	0	U2AF1	264732	0.05164274
789159	taxon:9606	2.62218371	4.50E-04	159691	1902	notch 2 N-terminal like	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NOTCH2NL				NOTCH2NL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH2NL	0.38136153	0.05347938	97	4	FALSE	NOTCH2NL	NOTCH2NL	51.46391753	0	97	0	0.72963605	FALSE	0	NOTCH2NL	945162	0.02212181
789549	taxon:9606	2.62218371	4.50E-04	142439	1902	notch homolog 2 N-terminal-like protein	gene		G:9606:LOC100996717				LOC100996717	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100996717	0.38136153	0.05347938	97	4	FALSE	LOC100996717	LOC100996717	51.46391753	0	97	0	0.72963605	FALSE	0	LOC100996717	945162	0.02212181
789557	taxon:9606	2.62218371	4.50E-04	142420	1902	notch homolog 2 N-terminal-like protein	gene		G:9606:LOC100996763				LOC100996763	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100996763	0.38136153	0.05347938	97	4	FALSE	LOC100996763	LOC100996763	51.46391753	0	97	0	0.72963605	FALSE	0	LOC100996763	945162	0.02212181
789674	taxon:9606	2.28013235	5.62E-04	174922	1902	TGF-beta activated kinase 1 (MAP3K7) binding protein 1	gene	biological_process-&-1&-GO:0003279-&&-cardiac septum development-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0035904-&&-aorta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0030324-&&-lung development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0019209-&&-kinase activator activity	G:9606:TAB1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05161-&&-Hepatitis B	TAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAB1	0.43857103	0.10839866	97	4	FALSE	TAB1	TAB1	158.8421053	0	96	0	0.78664461	FALSE	1	TAB1	715936	0.0354274
789738	taxon:9606	2.24499764	6.47E-04	174789	1902	RAN binding protein 9	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006461-&&-protein complex assembly-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:RANBP9				RANBP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP9	0.44543477	0.07995521	97	4	FALSE	RANBP9	RANBP9	167.6421053	0	96	0	0.79250039	FALSE	1	RANBP9	863104	0.03568011
789781	taxon:9606	2.27430282	1.64E-04	174692	1902	Aly/REF export factor	gene	biological_process-&-1&-GO:0031297-&&-replication fork processing-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000346-&&-transcription export complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:ALYREF			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	ALYREF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALYREF	0.43969519	0.21724524	97	4	FALSE	ALYREF	ALYREF	256.4421053	0	96	0	0.7876162	FALSE	1	ALYREF	466594	0.05665744
789846	taxon:9606	2.33244052	1.96E-04	174521	1902	splicing factor 3a subunit 3	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SF3A3			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3A3	0.42873548	0.20468213	97	4	FALSE	SF3A3	SF3A3	207.0103093	0	97	0	0.77792658	FALSE	0	SF3A3	440068	0.04974766
790265	taxon:9606	2.39814085	4.60E-04	173482	1902	nicastrin	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0016485-&&-protein processing-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0034205-&&-beta-amyloid formation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0042982-&&-amyloid precursor protein metabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0070765-&&-gamma-secretase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity	G:9606:NCSTN			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease	NCSTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCSTN	0.41698969	0.09750859	97	4	FALSE	NCSTN	NCSTN	119.4329897	0	97	0	0.76697652	FALSE	0	NCSTN	691294	0.03186604
790556	taxon:9606	2.3997164	9.59E-05	139396	1902	U2 small nuclear RNA auxiliary factor 1 like 5	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0089701-&&-U2AF-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:U2AF1L5			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa05131-&&-Shigellosis	U2AF1L5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2AF1L5	0.41671591	0.26181271	97	4	FALSE	U2AF1L5	U2AF1L5	193.4123711	0	97	0	0.76671393	FALSE	0	U2AF1L5	264732	0.05164274
792147	taxon:9606	2.32251457	3.03E-04	182522	1902	actin like 6A	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007165-&&-signal transduction-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0003407-&&-neural retina development-%%-GO:0006310-&&-DNA recombination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0021510-&&-spinal cord development-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071564-&&-npBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0031011-&&-Ino80 complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ACTL6A			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	ACTL6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTL6A	0.4305678	0.16043814	97	4	FALSE	ACTL6A	ACTL6A	193.2474227	0	97	0	0.7795809	FALSE	0	ACTL6A	587082	0.0457401
793242	taxon:9606	2.25271782	2.29E-04	180466	1902	isoleucyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006428-&&-isoleucyl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0004822-&&-isoleucine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:IARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	IARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IARS	0.44390824	0.15141753	97	4	FALSE	IARS	IARS	208.371134	0	97	0	0.7912137	FALSE	0	IARS	555108	0.04473403
787848	taxon:9606	2.2886403	3.96E-04	178726	1902	eukaryotic translation initiation factor 2 alpha kinase 2	gene	biological_process-&-1&-GO:0032722-&&-positive regulation of chemokine production-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0010998-&&-regulation of translational initiation by eIF2 alpha phosphorylation-%%-GO:0009615-&&-response to virus-%%-GO:0009636-&&-response to toxic substance-%%-GO:1900225-&&-regulation of NLRP3 inflammasome complex assembly-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:1902033-&&-regulation of hematopoietic stem cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051607-&&-defense response to virus-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:1901532-&&-regulation of hematopoietic progenitor cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006412-&&-translation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030683-&&-evasion or tolerance by virus of host immune response-%%-GO:0035455-&&-response to interferon-alpha-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1902036-&&-regulation of hematopoietic stem cell differentiation-%%-GO:0001819-&&-positive regulation of cytokine production|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004694-&&-eukaryotic translation initiation factor 2alpha kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005524-&&-ATP binding	G:9606:EIF2AK2	EIF2AK2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05165-&&-Human papillomavirus infection	EIF2AK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2AK2	0.43694066	0.10546786	96	4	FALSE	EIF2AK2	EIF2AK2	166.1595745	0	95	0	0.78522662	FALSE	1	EIF2AK2	591454	0.03745467
787976	taxon:9606	2.31038286	4.39E-04	178479	1902	protein-L-isoaspartate (D-aspartate) O-methyltransferase	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0030091-&&-protein repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004719-&&-protein-L-isoaspartate (D-aspartate) O-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PCMT1				PCMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCMT1	0.4328287	0.0837337	96	4	FALSE	PCMT1	PCMT1	200.393617	0	95	0	0.78160286	FALSE	1	PCMT1	797382	0.0466994
788650	taxon:9606	2.46021743	0.00268137	177249	1902	transforming growth factor beta 1	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0060312-&&-regulation of blood vessel remodeling-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0060751-&&-branch elongation involved in mammary gland duct branching-%%-GO:0061035-&&-regulation of cartilage development-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0060364-&&-frontal suture morphogenesis-%%-GO:0085029-&&-extracellular matrix assembly-%%-GO:0010936-&&-negative regulation of macrophage cytokine production-%%-GO:0021915-&&-neural tube development-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:1990314-&&-cellular response to insulin-like growth factor stimulus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0009749-&&-response to glucose-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:1905313-&&-transforming growth factor beta receptor signaling pathway involved in heart development-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0048298-&&-positive regulation of isotype switching to IgA isotypes-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0060965-&&-negative regulation of gene silencing by miRNA-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0006954-&&-inflammatory response-%%-GO:0002460-&&-adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0046732-&&-active induction of host immune response by virus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051280-&&-negative regulation of release of sequestered calcium ion into cytosol-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043932-&&-ossification involved in bone remodeling-%%-GO:0070723-&&-response to cholesterol-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0042306-&&-regulation of protein import into nucleus-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0032943-&&-mononuclear cell proliferation-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0033280-&&-response to vitamin D-%%-GO:0043117-&&-positive regulation of vascular permeability-%%-GO:0007507-&&-heart development-%%-GO:0048468-&&-cell development-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007406-&&-negative regulation of neuroblast proliferation-%%-GO:0007568-&&-aging-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0045066-&&-regulatory T cell differentiation-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032570-&&-response to progesterone-%%-GO:0002513-&&-tolerance induction to self antigen-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0008354-&&-germ cell migration-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042552-&&-myelination-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007492-&&-endoderm development-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0048535-&&-lymph node development-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0032355-&&-response to estradiol-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0009611-&&-response to wounding-%%-GO:1901666-&&-positive regulation of NAD+ ADP-ribosyltransferase activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0032667-&&-regulation of interleukin-23 production-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1990402-&&-embryonic liver development-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:1905005-&&-regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0048565-&&-digestive tract development-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0001570-&&-vasculogenesis-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0019049-&&-evasion or tolerance of host defenses by virus-%%-GO:0060325-&&-face morphogenesis-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0051101-&&-regulation of DNA binding-%%-GO:0010716-&&-negative regulation of extracellular matrix disassembly-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0016477-&&-cell migration-%%-GO:0048839-&&-inner ear development-%%-GO:0097421-&&-liver regeneration-%%-GO:0060390-&&-regulation of SMAD protein import into nucleus-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:1903911-&&-positive regulation of receptor clustering-%%-GO:0045591-&&-positive regulation of regulatory T cell differentiation-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0016049-&&-cell growth-%%-GO:0001843-&&-neural tube closure-%%-GO:0009817-&&-defense response to fungus, incompatible interaction-%%-GO:0042482-&&-positive regulation of odontogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0051098-&&-regulation of binding|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0030424-&&-axon-%%-GO:0005576-&&-extracellular region-%%-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005634-&&-nucleus-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034714-&&-type III transforming growth factor beta receptor binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0003823-&&-antigen binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity	G:9606:TGFB1	TGFB1	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05144-&&-Malaria-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05226-&&-Gastric cancer	TGFB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFB1	0.40646814	0.0295127	96	4	FALSE	TGFB1	TGFB1	68.45744681	0	95	0	0.75663043	FALSE	1	TGFB1	2492550	0.02040862
789344	taxon:9606	2.32440523	2.70E-04	175693	1902	pre-mRNA processing factor 4	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0071001-&&-U4/U6 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097525-&&-spliceosomal snRNP complex|molecular_function-&-1&-GO:0017070-&&-U6 snRNA binding-%%-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:PRPF4			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF4	0.43021758	0.18142302	96	4	FALSE	PRPF4	PRPF4	209.0106383	0	95	0	0.77926579	FALSE	1	PRPF4	521066	0.04969515
790036	taxon:9606	2.52906885	2.03E-04	174045	1902	centriolin	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051301-&&-cell division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:CNTRL				CNTRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNTRL	0.39540244	0.08048246	96	4	FALSE	CNTRL	CNTRL	81.40625	0	96	0	0.74515519	FALSE	0	CNTRL	296606	0.02781222
790244	taxon:9606	2.5090594	2.63E-04	173532	1902	RPGRIP1 like	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0021549-&&-cerebellum development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0043584-&&-nose development-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0043010-&&-camera-type eye development-%%-GO:0060039-&&-pericardium development-%%-GO:0001822-&&-kidney development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0001889-&&-liver development-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0022038-&&-corpus callosum development-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0021532-&&-neural tube patterning-%%-GO:0090102-&&-cochlea development|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005930-&&-axoneme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005929-&&-cilium-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005879-&&-axonemal microtubule-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031870-&&-thromboxane A2 receptor binding	G:9606:RPGRIP1L				RPGRIP1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPGRIP1L	0.39855573	0.05921053	96	4	FALSE	RPGRIP1L	RPGRIP1L	79.16666667	0	96	0	0.7484901	FALSE	0	RPGRIP1L	339572	0.02583238
792070	taxon:9606	2.48684418	4.58E-04	182660	1902	CDC like kinase 1	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008283-&&-cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:CLK1	CLK1	TRUE	KEGG-&-1&-hsa05134-&&-Legionellosis	CLK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLK1	0.40211607	0.05399222	96	4	FALSE	CLK1	CLK1	94.94680851	0	95	0	0.75219264	FALSE	1	CLK1	532822	0.02972711
787224	taxon:9606	2.34614779	1.57E-04	179832	1902	minichromosome maintenance complex component 6	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0042555-&&-MCM complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:MCM6			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03030-&&-DNA replication	MCM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM6	0.42623061	0.25549322	95	4	FALSE	MCM6	MCM6	236.6774194	0	94	0	0.77564204	FALSE	1	MCM6	394466	0.05795865
787570	taxon:9606	2.38411848	4.58E-04	179159	1902	NADH:ubiquinone oxidoreductase core subunit S3	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0045333-&&-cellular respiration-%%-GO:0021762-&&-substantia nigra development|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0016604-&&-nuclear body-%%-GO:0031966-&&-mitochondrial membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity	G:9606:NDUFS3			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS3	0.41944224	0.14703132	95	4	FALSE	NDUFS3	NDUFS3	142.0537634	0	94	0	0.76931359	FALSE	1	NDUFS3	696504	0.03703299
788492	taxon:9606	2.43422089	2.81E-04	177552	1902	small nuclear ribonucleoprotein polypeptides B and B1	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0051170-&&-nuclear import-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071004-&&-U2-type prespliceosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005686-&&-U2 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005683-&&-U7 snRNP|molecular_function-&-1&-GO:0030620-&&-U2 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0071208-&&-histone pre-mRNA DCP binding	G:9606:SNRPB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa03040-&&-Spliceosome	SNRPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPB	0.41080906	0.13931744	95	4	FALSE	SNRPB	SNRPB	164.3548387	0	94	0	0.76096318	FALSE	1	SNRPB	474532	0.04659803
789320	taxon:9606	2.36568458	4.18E-04	175747	1902	MAGE family member D1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000785-&&-chromatin-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding	G:9606:MAGED1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	MAGED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGED1	0.42271062	0.06241234	95	4	FALSE	MAGED1	MAGED1	125	0	94	0	0.7723859	FALSE	1	MAGED1	536512	0.03161067
789379	taxon:9606	2.35512841	2.20E-04	175621	1902	metastasis associated 1 family member 2	gene	biological_process-&-1&-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006306-&&-DNA methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006333-&&-chromatin assembly or disassembly-%%-GO:0016575-&&-histone deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016020-&&-membrane-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016581-&&-NuRD complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding	G:9606:MTA2				MTA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTA2	0.4246053	0.18118701	95	4	FALSE	MTA2	MTA2	196.1894737	0	95	0	0.77414527	FALSE	0	MTA2	489548	0.04852051
791463	taxon:9606	2.31321884	2.69E-04	168539	1902	WD repeat domain 77	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034709-&&-methylosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0005515-&&-protein binding	G:9606:WDR77				WDR77	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR77	0.43229805	0.13277232	95	4	FALSE	WDR77	WDR77	203	0	94	0	0.78113019	FALSE	1	WDR77	568164	0.04735849
792055	taxon:9606	2.43563888	5.74E-04	182683	1902	basigin (Ok blood group)	gene	biological_process-&-1&-GO:0043434-&&-response to peptide hormone-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0015718-&&-monocarboxylic acid transport-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0046689-&&-response to mercury ion-%%-GO:0046697-&&-decidualization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007566-&&-embryo implantation-%%-GO:0051591-&&-response to cAMP|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042383-&&-sarcolemma-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0005515-&&-protein binding-%%-GO:0008028-&&-monocarboxylic acid transmembrane transporter activity-%%-GO:0045296-&&-cadherin binding	G:9606:BSG				BSG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BSG	0.41056989	0.03856942	95	4	FALSE	BSG	BSG	101.516129	0	94	0	0.76072685	FALSE	1	BSG	630942	0.02893986
792419	taxon:9606	2.26453443	4.36E-04	182054	1902	casein kinase 1 alpha 1	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051301-&&-cell division-%%-GO:0007030-&&-Golgi organization-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006909-&&-phagocytosis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1904424-&&-regulation of GTP binding-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0008360-&&-regulation of cell shape|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005929-&&-cilium-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0016020-&&-membrane-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CSNK1A1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer-%%-hsa05165-&&-Human papillomavirus infection	CSNK1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1A1	0.44159187	0.10795073	95	4	FALSE	CSNK1A1	CSNK1A1	175	0	95	0	0.78924426	FALSE	0	CSNK1A1	665056	0.03817167
792743	taxon:9606	2.27745392	5.74E-04	181458	1902	dynamin 2	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0061025-&&-membrane fusion-%%-GO:0006897-&&-endocytosis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0003281-&&-ventricular septum development-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:1903526-&&-negative regulation of membrane tubulation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0071245-&&-cellular response to carbon monoxide-%%-GO:0031623-&&-receptor internalization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0006909-&&-phagocytosis-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0035904-&&-aorta development-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0009416-&&-response to light stimulus-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0044351-&&-macropinocytosis-%%-GO:1903408-&&-positive regulation of sodium:potassium-exchanging ATPase activity-%%-GO:0042220-&&-response to cocaine-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0007165-&&-signal transduction-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0033572-&&-transferrin transport-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:1902856-&&-negative regulation of non-motile cilium assembly-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0048812-&&-neuron projection morphogenesis|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0005768-&&-endosome-%%-GO:0005874-&&-microtubule-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001891-&&-phagocytic cup|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031749-&&-D2 dopamine receptor binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:DNM2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04721-&&-Synaptic vesicle cycle	DNM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM2	0.43908682	0.08846585	95	4	FALSE	DNM2	DNM2	169.0210526	0	95	0	0.78709101	FALSE	0	DNM2	852866	0.03750788
793341	taxon:9606	2.32314479	4.50E-04	180269	1902	high mobility group box 1	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0043371-&&-negative regulation of CD4-positive, alpha-beta T cell differentiation-%%-GO:0050716-&&-positive regulation of interleukin-1 secretion-%%-GO:0032425-&&-positive regulation of mismatch repair-%%-GO:0034165-&&-positive regulation of toll-like receptor 9 signaling pathway-%%-GO:0001773-&&-myeloid dendritic cell activation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0050918-&&-positive chemotaxis-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0006914-&&-autophagy-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006310-&&-DNA recombination-%%-GO:0032072-&&-regulation of restriction endodeoxyribonuclease activity-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045063-&&-T-helper 1 cell differentiation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0006265-&&-DNA topological change-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051106-&&-positive regulation of DNA ligation-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0002840-&&-regulation of T cell mediated immune response to tumor cell-%%-GO:0006954-&&-inflammatory response-%%-GO:1990774-&&-tumor necrosis factor secretion-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0035711-&&-T-helper 1 cell activation-%%-GO:0002643-&&-regulation of tolerance induction-%%-GO:0017055-&&-negative regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0032392-&&-DNA geometric change-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0043410-&&-positive regulation of MAPK cascade|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0000793-&&-condensed chromosome|molecular_function-&-1&-GO:0000405-&&-bubble DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0097100-&&-supercoiled DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0016829-&&-lyase activity-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0019958-&&-C-X-C chemokine binding	G:9606:HMGB1	HMGB1	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa03410-&&-Base excision repair-%%-hsa04217-&&-Necroptosis	HMGB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGB1	0.430451	0.0837626	95	4	FALSE	HMGB1	HMGB1	153.7684211	0	95	0	0.77947587	FALSE	0	HMGB1	663332	0.03652692
787261	taxon:9606	2.32440523	6.61E-04	179784	1902	Janus kinase 1	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:1903672-&&-positive regulation of sprouting angiogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0038110-&&-interleukin-2-mediated signaling pathway-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0046677-&&-response to antibiotic-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005131-&&-growth hormone receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:JAK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK1	0.43021758	0.13043478	94	4	FALSE	JAK1	JAK1	135.8586957	0	93	0	0.77926579	FALSE	1	JAK1	824476	0.03225257
787773	taxon:9606	2.40712147	2.52E-04	178806	1902	protein phosphatase, Mg2+/Mn2+ dependent 1G	gene	biological_process-&-1&-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity	G:9606:PPM1G				PPM1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1G	0.41543396	0.10867078	94	4	FALSE	PPM1G	PPM1G	157.5851064	0	94	0	0.76547975	FALSE	0	PPM1G	475926	0.04259058
787837	taxon:9606	2.32219946	4.38E-04	178732	1902	mitogen-activated protein kinase kinase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0060020-&&-Bergmann glial cell differentiation-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0007507-&&-heart development-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0030878-&&-thyroid gland development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0021697-&&-cerebellar cortex formation-%%-GO:0048679-&&-regulation of axon regeneration-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0035897-&&-proteolysis in other organism-%%-GO:0060324-&&-face development-%%-GO:0060502-&&-epithelial cell proliferation involved in lung morphogenesis-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0048538-&&-thymus development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0048870-&&-cell motility-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006935-&&-chemotaxis-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0060440-&&-trachea formation-%%-GO:0090398-&&-cellular senescence|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005770-&&-late endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004728-&&-signal transducer, downstream of receptor, with protein tyrosine phosphatase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:MAP2K1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05020-&&-Prion diseases-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	MAP2K1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K1	0.43062623	0.09173435	94	4	FALSE	MAP2K1	MAP2K1	141.2717391	0	93	0	0.77963342	FALSE	1	MAP2K1	632920	0.03335319
788229	taxon:9606	2.43878998	0.00122828	178040	1902	small glutamine rich tetratricopeptide repeat containing alpha	gene	biological_process-&-1&-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1903070-&&-negative regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0008150-&&-biological_process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:1904288-&&-BAT3 complex binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding	G:9606:SGTA				SGTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGTA	0.41003941	0.03917821	94	4	FALSE	SGTA	SGTA	92.26086957	0	93	0	0.76020167	FALSE	1	SGTA	1314576	0.02649672
788798	taxon:9606	2.29998424	3.27E-04	176848	1902	tubulin beta 2A class IIa	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB2A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB2A	0.43478559	0.09723175	94	4	FALSE	TUBB2A	TUBB2A	169.5531915	0	94	0	0.78333596	FALSE	0	TUBB2A	607196	0.03885185
788962	taxon:9606	2.4244525	5.93E-04	176527	1902	phosphoinositide-3-kinase regulatory subunit 3	gene	biological_process-&-1&-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0008286-&&-insulin receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex|molecular_function-&-1&-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:PIK3R3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3R3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R3	0.41246426	0.08670785	94	4	FALSE	PIK3R3	PIK3R3	100.9042553	0	94	0	0.76259125	FALSE	0	PIK3R3	633648	0.02820698
789697	taxon:9606	2.27414527	1.54E-04	174870	1902	MYB binding protein 1a	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0071897-&&-DNA biosynthetic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042564-&&-NLS-dependent protein nuclear import complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding	G:9606:MYBBP1A				MYBBP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYBBP1A	0.43972565	0.2736216	94	4	FALSE	MYBBP1A	MYBBP1A	254.5744681	0	94	0	0.78764246	FALSE	0	MYBBP1A	425612	0.05623235
789734	taxon:9606	2.48857728	1.31E-04	174799	1902	chromatin assembly factor 1 subunit A	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0031497-&&-chromatin assembly-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007049-&&-cell cycle-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0033186-&&-CAF-1 complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0070087-&&-chromo shadow domain binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CHAF1A				CHAF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHAF1A	0.40183602	0.21118012	94	4	FALSE	CHAF1A	CHAF1A	183.25	0	93	0	0.75190379	FALSE	1	CHAF1A	311954	0.05723415
789831	taxon:9606	2.44966126	1.79E-04	174544	1902	euchromatic histone lysine methyltransferase 2	gene	biological_process-&-1&-GO:0006306-&&-DNA methylation-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0009267-&&-cellular response to starvation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016571-&&-histone methylation-%%-GO:0070734-&&-histone H3-K27 methylation-%%-GO:0051567-&&-histone H3-K9 methylation-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0018027-&&-peptidyl-lysine dimethylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0046976-&&-histone methyltransferase activity (H3-K27 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0002039-&&-p53 binding-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:EHMT2			KEGG-&-1&-hsa00310-&&-Lysine degradation-%%-hsa04211-&&-Longevity regulating pathway	EHMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHMT2	0.40821971	0.16817965	94	4	FALSE	EHMT2	EHMT2	159.5652174	0	93	0	0.75838979	FALSE	1	EHMT2	404510	0.04635912
790063	taxon:9606	2.5853159	1.65E-04	173970	1902	protein tyrosine phosphatase type IVA, member 3	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:1900746-&&-regulation of vascular endothelial growth factor signaling pathway-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0043117-&&-positive regulation of vascular permeability|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0004727-&&-prenylated protein tyrosine phosphatase activity	G:9606:PTP4A3				PTP4A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTP4A3	0.38679993	0.02150024	94	4	FALSE	PTP4A3	PTP4A3	72.7173913	0	93	0	0.73578068	FALSE	1	PTP4A3	260390	0.0282974
791805	taxon:9606	2.44524972	3.41E-04	166787	1902	leucine zipper tumor suppressor 2	gene	biological_process-&-1&-GO:0001822-&&-kidney development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1900181-&&-negative regulation of protein localization to nucleus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:LZTS2				LZTS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LZTS2	0.40895619	0.03568977	94	4	FALSE	LZTS2	LZTS2	95.81914894	0	94	0	0.75912505	FALSE	0	LZTS2	485956	0.02773358
792631	taxon:9606	2.34961399	3.78E-04	181686	1902	eukaryotic translation elongation factor 1 alpha 2	gene	biological_process-&-1&-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0006414-&&-translational elongation-%%-GO:0090218-&&-positive regulation of lipid kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0010035-&&-response to inorganic substance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0098574-&&-cytoplasmic side of lysosomal membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:EEF1A2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05134-&&-Legionellosis	EEF1A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1A2	0.42560182	0.11988103	94	4	FALSE	EEF1A2	EEF1A2	186.0106383	0	94	0	0.77506433	FALSE	0	EEF1A2	569120	0.04597828
792768	taxon:9606	2.32062392	2.53E-04	181411	1902	DNA methyltransferase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006306-&&-DNA methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0090309-&&-positive regulation of methylation-dependent chromatin silencing-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0090116-&&-C-5 methylation of cytosine-%%-GO:0016458-&&-gene silencing-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005721-&&-pericentric heterochromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003886-&&-DNA (cytosine-5-)-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:DNMT1			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer	DNMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT1	0.4309186	0.22216914	94	4	FALSE	DNMT1	DNMT1	203.9021739	0	93	0	0.77989601	FALSE	1	DNMT1	481032	0.04808501
793366	taxon:9606	2.34346936	2.15E-04	180235	1902	heterogeneous nuclear ribonucleoprotein H2	gene	biological_process-&-1&-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH2				HNRNPH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH2	0.42671776	0.23315815	94	4	FALSE	HNRNPH2	HNRNPH2	207.9565217	0	93	0	0.77608844	FALSE	1	HNRNPH2	386332	0.05079988
787313	taxon:9606	2.32928943	2.03E-04	179677	1902	importin 5	gene	biological_process-&-1&-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0003723-&&-RNA binding	G:9606:IPO5				IPO5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO5	0.42931548	0.1313698	93	4	FALSE	IPO5	IPO5	189.7526882	0	93	0	0.77845176	FALSE	0	IPO5	419620	0.04533857
787454	taxon:9606	2.43296045	2.15E-04	179401	1902	menin 1	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0061469-&&-regulation of type B pancreatic cell proliferation-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0009411-&&-response to UV-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0046697-&&-decidualization-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0002076-&&-osteoblast development-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0003309-&&-type B pancreatic cell differentiation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0006281-&&-DNA repair-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007420-&&-brain development-%%-GO:0010332-&&-response to gamma radiation-%%-GO:1902807-&&-negative regulation of cell cycle G1/S phase transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071375-&&-cellular response to peptide hormone stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000785-&&-chromatin-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0000403-&&-Y-form DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0070412-&&-R-SMAD binding	G:9606:MEN1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04934-&&-Cushing syndrome	MEN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEN1	0.41102189	0.1659654	93	4	FALSE	MEN1	MEN1	200.8602151	0	93	0	0.76117326	FALSE	0	MEN1	475802	0.0565523
787700	taxon:9606	2.28722231	2.65E-04	178923	1902	plectin	gene	biological_process-&-1&-GO:0031581-&&-hemidesmosome assembly|cellular_component-&-1&-GO:0016528-&&-sarcoplasm-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005903-&&-brush border-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042383-&&-sarcolemma-%%-GO:0043034-&&-costamere-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0030506-&&-ankyrin binding-%%-GO:0003723-&&-RNA binding	G:9606:PLEC				PLEC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLEC	0.43721155	0.13207106	93	4	FALSE	PLEC	PLEC	211.2688172	0	93	0	0.78546295	FALSE	0	PLEC	546780	0.04759724
787995	taxon:9606	2.37214432	4.49E-04	178438	1902	platelet derived growth factor receptor beta	gene	biological_process-&-1&-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0060326-&&-cell chemotaxis-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0043627-&&-response to estrogen-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0072277-&&-metanephric glomerular capillary formation-%%-GO:0060437-&&-lung growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0072284-&&-metanephric S-shaped body morphogenesis-%%-GO:0035789-&&-metanephric mesenchymal cell migration-%%-GO:0042060-&&-wound healing-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0060981-&&-cell migration involved in coronary angiogenesis-%%-GO:0072278-&&-metanephric comma-shaped body morphogenesis-%%-GO:0071670-&&-smooth muscle cell chemotaxis-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0035793-&&-positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0016477-&&-cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0072262-&&-metanephric glomerular mesangial cell proliferation involved in metanephros development-%%-GO:0007568-&&-aging-%%-GO:0008584-&&-male gonad development-%%-GO:0032355-&&-response to estradiol-%%-GO:0038091-&&-positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0035441-&&-cell migration involved in vasculogenesis-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0048839-&&-inner ear development-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0072075-&&-metanephric mesenchyme development-%%-GO:0061298-&&-retina vasculature development in camera-type eye|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031226-&&-intrinsic component of plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005017-&&-platelet-derived growth factor-activated receptor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005019-&&-platelet-derived growth factor beta-receptor activity-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004992-&&-platelet activating factor receptor activity-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0019901-&&-protein kinase binding	G:9606:PDGFRB			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton	PDGFRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFRB	0.42155951	0.13797314	93	4	FALSE	PDGFRB	PDGFRB	121.7142857	0	92	0	0.77130928	FALSE	1	PDGFRB	516824	0.0311182
788571	taxon:9606	2.41941075	3.04E-04	177413	1902	TATA-box binding protein associated factor 9	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0060760-&&-positive regulation of response to cytokine stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000125-&&-PCAF complex-%%-GO:0070761-&&-pre-snoRNP complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0002039-&&-p53 binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0003677-&&-DNA binding	G:9606:TAF9			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF9	0.41332378	0.1201496	93	4	FALSE	TAF9	TAF9	137.8064516	0	93	0	0.76343154	FALSE	0	TAF9	469808	0.0380594
788768	taxon:9606	2.41106034	3.63E-04	176944	1902	zyxin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0016032-&&-viral process-%%-GO:0050727-&&-regulation of inflammatory response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:ZYX			KEGG-&-1&-hsa04510-&&-Focal adhesion	ZYX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZYX	0.41475528	0.08578775	93	4	FALSE	ZYX	ZYX	142.9247312	0	93	0	0.76482328	FALSE	0	ZYX	576390	0.0389884
788996	taxon:9606	2.43989286	2.31E-04	160051	1902	glutathione S-transferase kappa 1	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005622-&&-intracellular-%%-GO:0005777-&&-peroxisome-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0005515-&&-protein binding	G:9606:GSTK1			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05204-&&-Chemical carcinogenesis	GSTK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTK1	0.40985406	0.05323565	93	4	FALSE	GSTK1	GSTK1	105.967033	0	92	0	0.76001786	FALSE	1	GSTK1	340196	0.03039883
789955	taxon:9606	2.34189381	1.99E-04	174255	1902	heat shock protein family H (Hsp110) member 1	gene	biological_process-&-1&-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:1903748-&&-negative regulation of establishment of protein localization to mitochondrion-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1903751-&&-negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0051135-&&-positive regulation of NK T cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity	G:9606:HSPH1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPH1	0.42700484	0.13931744	93	4	FALSE	HSPH1	HSPH1	180.2795699	0	93	0	0.77635103	FALSE	0	HSPH1	410642	0.04380773
790423	taxon:9606	2.42350717	2.13E-04	173032	1902	FtsJ RNA methyltransferase homolog 1 (E. coli)	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0030488-&&-tRNA methylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0052666-&&-tRNA (cytosine-2'-O-)-methyltransferase activity-%%-GO:0009020-&&-tRNA (guanosine-2'-O-)-methyltransferase activity	G:9606:FTSJ1				FTSJ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTSJ1	0.41262515	0.04908836	93	4	FALSE	FTSJ1	FTSJ1	109.3225807	0	93	0	0.76274881	FALSE	0	FTSJ1	340912	0.03051504
790916	taxon:9606	2.39908618	2.81E-04	170701	1902	protein inhibitor of activated STAT 4	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016925-&&-protein sumoylation-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1902174-&&-positive regulation of keratinocyte apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:1990234-&&-transferase complex-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0019789-&&-SUMO transferase activity-%%-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PIAS4			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04064-&&-NF-kappa B signaling pathway	PIAS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS4	0.41682538	0.0972417	93	4	FALSE	PIAS4	PIAS4	127.0322581	0	93	0	0.76681897	FALSE	0	PIAS4	436924	0.03387283
790924	taxon:9606	2.41436899	1.12E-04	170694	1902	NOP58 ribonucleoprotein	gene	biological_process-&-1&-GO:0016049-&&-cell growth-%%-GO:0048254-&&-snoRNA localization-%%-GO:0006608-&&-snRNP protein import into nucleus-%%-GO:0006364-&&-rRNA processing-%%-GO:0000154-&&-rRNA modification|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031428-&&-box C/D snoRNP complex-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0070761-&&-pre-snoRNP complex|molecular_function-&-1&-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NOP58			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NOP58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP58	0.4141869	0.27325853	93	4	FALSE	NOP58	NOP58	193.2795699	0	93	0	0.76427183	FALSE	0	NOP58	258676	0.05284313
792303	taxon:9606	2.40223728	3.64E-04	182259	1902	CCAAT/enhancer binding protein alpha	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0048839-&&-inner ear development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0001889-&&-liver development-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0016032-&&-viral process-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0048469-&&-cell maturation-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0030324-&&-lung development|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019900-&&-kinase binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:CEBPA			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	CEBPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPA	0.41627861	0.13382173	93	4	FALSE	CEBPA	CEBPA	132.7252747	0	92	0	0.76629379	FALSE	1	CEBPA	504940	0.03554281
787245	taxon:9606	2.2569718	3.52E-04	179805	1902	insulin receptor substrate 1	gene	biological_process-&-1&-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0032868-&&-response to insulin-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola-%%-GO:0005737-&&-cytoplasm-%%-GO:0005899-&&-insulin receptor complex|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0004871-&&-signal transducer activity	G:9606:IRS1	IRS1	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04022-&&-cGMP-PKG signaling pathway	IRS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRS1	0.44307155	0.16254682	92	4	FALSE	IRS1	IRS1	180.2555556	0	91	0	0.7905047	FALSE	1	IRS1	570238	0.0388793
787303	taxon:9606	2.60847645	2.65E-04	179699	1902	KIT proto-oncogene receptor tyrosine kinase	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0008584-&&-male gonad development-%%-GO:0032762-&&-mast cell cytokine production-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1905065-&&-positive regulation of vascular smooth muscle cell differentiation-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002371-&&-dendritic cell cytokine production-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0043473-&&-pigmentation-%%-GO:0097326-&&-melanocyte adhesion-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0038093-&&-Fc receptor signaling pathway-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0060374-&&-mast cell differentiation-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0007286-&&-spermatid development-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0002327-&&-immature B cell differentiation-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0097324-&&-melanocyte migration-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048103-&&-somatic stem cell division-%%-GO:0008542-&&-visual learning-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0035701-&&-hematopoietic stem cell migration-%%-GO:0008354-&&-germ cell migration-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0048170-&&-positive regulation of long-term neuronal synaptic plasticity-%%-GO:0048565-&&-digestive tract development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0038162-&&-erythropoietin-mediated signaling pathway-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0048070-&&-regulation of developmental pigmentation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0038109-&&-Kit signaling pathway-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0030097-&&-hemopoiesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070662-&&-mast cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005911-&&-cell-cell junction-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019955-&&-cytokine binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005020-&&-stem cell factor receptor activity	G:9606:KIT			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage	KIT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIT	0.38336555	0.13882647	92	4	FALSE	KIT	KIT	83.15555556	0	91	0	0.73192059	FALSE	1	KIT	324420	0.03426804
787458	taxon:9606	2.51945801	9.86E-04	179399	1902	mesenchyme homeobox 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0070997-&&-neuron death-%%-GO:0060021-&&-palate development-%%-GO:0060173-&&-limb development-%%-GO:0001525-&&-angiogenesis-%%-GO:0001757-&&-somite specification-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008015-&&-blood circulation-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0061053-&&-somite development|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:MEOX2				MEOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEOX2	0.39691076	0.03081701	92	4	FALSE	MEOX2	MEOX2	72.33695652	0	92	0	0.746757	FALSE	0	MEOX2	1129696	0.0244252
789314	taxon:9606	2.52134867	2.64E-04	175764	1902	mediator complex subunit 20	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED20				MED20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED20	0.39661314	0.09149546	92	4	FALSE	MED20	MED20	82.76086957	0	92	0	0.74644189	FALSE	0	MED20	332064	0.02775628
789652	taxon:9606	2.41562943	2.21E-04	174969	1902	N-myc downstream regulated 1	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:0010038-&&-response to metal ion-%%-GO:0045576-&&-mast cell activation-%%-GO:0090232-&&-positive regulation of spindle checkpoint|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0043015-&&-gamma-tubulin binding	G:9606:NDRG1				NDRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDRG1	0.41397078	0.0931677	92	4	FALSE	NDRG1	NDRG1	144.8695652	0	92	0	0.76406176	FALSE	0	NDRG1	368584	0.03972983
791551	taxon:9606	2.39829841	2.95E-04	168062	1902	cell division cycle 73	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034402-&&-recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex-%%-GO:0031648-&&-protein destabilization-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007049-&&-cell cycle-%%-GO:0048147-&&-negative regulation of fibroblast proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016593-&&-Cdc73/Paf1 complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:CDC73	CDC73	TRUE		CDC73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC73	0.41696229	0.11801242	92	4	FALSE	CDC73	CDC73	148.923913	0	92	0	0.76695027	FALSE	0	CDC73	524280	0.03973224
791928	taxon:9606	2.28611943	3.40E-04	182860	1902	aldolase, fructose-bisphosphate A	gene	biological_process-&-1&-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006096-&&-glycolytic process-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007015-&&-actin filament organization-%%-GO:0006754-&&-ATP biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031674-&&-I band-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0031430-&&-M band-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0004332-&&-fructose-bisphosphate aldolase activity-%%-GO:0070061-&&-fructose binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0003779-&&-actin binding-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:ALDOA			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa00030-&&-Pentose phosphate pathway	ALDOA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDOA	0.43742247	0.14906367	92	4	FALSE	ALDOA	ALDOA	188.4666667	0	91	0	0.78564676	FALSE	1	ALDOA	569138	0.04230405
791943	taxon:9606	2.42082874	2.82E-04	182831	1902	autocrine motility factor receptor	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007611-&&-learning or memory-%%-GO:0007568-&&-aging-%%-GO:0051259-&&-protein oligomerization-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0036503-&&-ERAD pathway|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0004872-&&-receptor activity-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:1904288-&&-BAT3 complex binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:AMFR			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	AMFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMFR	0.41308168	0.13558052	92	4	FALSE	AMFR	AMFR	127.7666667	0	91	0	0.76319521	FALSE	1	AMFR	400576	0.03540589
792984	taxon:9606	2.34142114	2.67E-04	181040	1902	filamin B	gene	biological_process-&-1&-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0003334-&&-keratinocyte development-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007519-&&-skeletal muscle tissue development|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:FLNB			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNB	0.42709104	0.10811486	92	4	FALSE	FLNB	FLNB	181.6777778	0	91	0	0.77642981	FALSE	1	FLNB	498026	0.04421725
793092	taxon:9606	2.41090279	2.13E-04	180747	1902	glycyl-tRNA synthetase	gene	biological_process-&-1&-GO:0015966-&&-diadenosine tetraphosphate biosynthetic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006426-&&-glycyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0030141-&&-secretory granule-%%-GO:0030424-&&-axon|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004820-&&-glycine-tRNA ligase activity-%%-GO:0004081-&&-bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:GARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	GARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GARS	0.41478238	0.12637363	92	4	FALSE	GARS	GARS	150.4673913	0	92	0	0.76484954	FALSE	0	GARS	390190	0.04093759
787898	taxon:9606	2.42539783	1.61E-04	178641	1902	proteasome 26S subunit, non-ATPase 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:PSMD7			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD7	0.41230349	0.29279609	91	4	FALSE	PSMD7	PSMD7	138.1758242	0	91	0	0.7624337	FALSE	0	PSMD7	308730	0.03852283
788680	taxon:9606	2.5125256	4.50E-04	177210	1902	transducin like enhancer of split 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TLE1				TLE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLE1	0.39800589	0.06435138	91	4	FALSE	TLE1	TLE1	119.1685393	0	90	0	0.7479124	FALSE	1	TLE1	631812	0.03907115
789646	taxon:9606	2.31794549	3.57E-04	174983	1902	tubulin beta 4A class IVa	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005874-&&-microtubule-%%-GO:0005929-&&-cilium-%%-GO:0033269-&&-internode region of axon-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB4A			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB4A	0.43141653	0.0957265	91	4	FALSE	TUBB4A	TUBB4A	176.5824176	0	91	0	0.78034242	FALSE	0	TUBB4A	649884	0.04152812
789848	taxon:9606	2.33370096	9.14E-05	174518	1902	heterogeneous nuclear ribonucleoprotein A0	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0006954-&&-inflammatory response-%%-GO:0006397-&&-mRNA processing-%%-GO:0010467-&&-gene expression-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:HNRNPA0				HNRNPA0	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA0	0.42850392	0.30647131	91	4	FALSE	HNRNPA0	HNRNPA0	249.3516484	0	91	0	0.77771651	FALSE	0	HNRNPA0	253782	0.05992589
791887	taxon:9606	2.34677801	1.54E-04	166536	1902	ubiquitin associated and SH3 domain containing B	gene	biological_process-&-1&-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBASH3B				UBASH3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBASH3B	0.42611615	0.13355465	91	4	FALSE	UBASH3B	UBASH3B	162.9213483	0	90	0	0.775537	FALSE	1	UBASH3B	326744	0.04001877
787088	taxon:9606	2.38254293	4.60E-04	180088	1902	recombination signal binding protein for immunoglobulin kappa J region	gene	biological_process-&-1&-GO:0060486-&&-Clara cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0009912-&&-auditory receptor cell fate commitment-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:1901186-&&-positive regulation of ERBB signaling pathway-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0009957-&&-epidermal cell fate specification-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0006959-&&-humoral immune response-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0048505-&&-regulation of timing of cell differentiation-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0048733-&&-sebaceous gland development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1901297-&&-positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0060844-&&-arterial endothelial cell fate commitment-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001756-&&-somitogenesis-%%-GO:0003256-&&-regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:2000138-&&-positive regulation of cell proliferation involved in heart morphogenesis-%%-GO:0072554-&&-blood vessel lumenization-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0021983-&&-pituitary gland development-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:1901189-&&-positive regulation of ephrin receptor signaling pathway-%%-GO:0030183-&&-B cell differentiation-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0006310-&&-DNA recombination-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0003160-&&-endocardium morphogenesis-%%-GO:0097101-&&-blood vessel endothelial cell fate specification-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0002193-&&-MAML1-RBP-Jkappa- ICN1 complex|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000150-&&-recombinase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RBPJ			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	RBPJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBPJ	0.41971961	0.05867665	90	4	FALSE	RBPJ	RBPJ	118.1555556	0	90	0	0.76957618	FALSE	0	RBPJ	553524	0.03056634
787298	taxon:9606	2.36048527	3.02E-04	179714	1902	kinesin family member 5B	gene	biological_process-&-1&-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:1905152-&&-positive regulation of voltage-gated sodium channel activity-%%-GO:0072383-&&-plus-end-directed vesicle transport along microtubule-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0007028-&&-cytoplasm organization-%%-GO:0035617-&&-stress granule disassembly-%%-GO:0007411-&&-axon guidance-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0051642-&&-centrosome localization|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane-%%-GO:0044295-&&-axonal growth cone|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0008432-&&-JUN kinase binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0045296-&&-cadherin binding	G:9606:KIF5B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse	KIF5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF5B	0.4236417	0.08963795	90	4	FALSE	KIF5B	KIF5B	157.8333333	0	90	0	0.77325246	FALSE	0	KIF5B	494004	0.03949937
787866	taxon:9606	2.38774224	4.90E-04	178683	1902	presenilin 1	gene	biological_process-&-1&-GO:0051563-&&-smooth endoplasmic reticulum calcium ion homeostasis-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0015031-&&-protein transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0015871-&&-choline transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001708-&&-cell fate specification-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048538-&&-thymus development-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0048666-&&-neuron development-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0015813-&&-L-glutamate transport-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0007220-&&-Notch receptor processing-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0007613-&&-memory-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0003407-&&-neural retina development-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0009791-&&-post-embryonic development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0021870-&&-Cajal-Retzius cell differentiation-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0050820-&&-positive regulation of coagulation-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0001764-&&-neuron migration-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001568-&&-blood vessel development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0034205-&&-beta-amyloid formation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0016080-&&-synaptic vesicle targeting-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0016485-&&-protein processing-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0006486-&&-protein glycosylation-%%-GO:0060075-&&-regulation of resting membrane potential-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0001756-&&-somitogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0050771-&&-negative regulation of axonogenesis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0045121-&&-membrane raft-%%-GO:0000776-&&-kinetochore-%%-GO:0043198-&&-dendritic shaft-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005813-&&-centrosome-%%-GO:0030018-&&-Z disc-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0030426-&&-growth cone-%%-GO:0016235-&&-aggresome-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0070765-&&-gamma-secretase complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042500-&&-aspartic endopeptidase activity, intramembrane cleaving-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005262-&&-calcium channel activity	G:9606:PSEN1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa05165-&&-Human papillomavirus infection	PSEN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSEN1	0.41880567	0.06713689	90	4	FALSE	PSEN1	PSEN1	106.2045455	0	89	0	0.76870963	FALSE	1	PSEN1	587990	0.02783972
787879	taxon:9606	2.37119899	1.52E-04	178660	1902	proteasome subunit beta 5	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0006508-&&-proteolysis-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB5			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB5	0.42172757	0.29937578	90	4	FALSE	PSMB5	PSMB5	157.1888889	0	90	0	0.77146683	FALSE	0	PSMB5	329088	0.04007876
787914	taxon:9606	2.68016386	7.56E-04	178622	1902	prostaglandin E receptor 3	gene	biological_process-&-1&-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0060455-&&-negative regulation of gastric acid secretion-%%-GO:0008219-&&-cell death-%%-GO:0014827-&&-intestine smooth muscle contraction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0031622-&&-positive regulation of fever generation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0004957-&&-prostaglandin E receptor activity	G:9606:PTGER3	PTGER3	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	PTGER3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGER3	0.37311152	0.01822722	90	4	FALSE	PTGER3	PTGER3	45.43333333	0	90	0	0.71997269	FALSE	0	PTGER3	714972	0.02304358
788372	taxon:9606	2.3666299	3.30E-04	177784	1902	tripartite motif containing 21	gene	biological_process-&-1&-GO:0070206-&&-protein trimerization-%%-GO:0031648-&&-protein destabilization-%%-GO:0045087-&&-innate immune response-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0090086-&&-negative regulation of protein deubiquitination-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0046598-&&-positive regulation of viral entry into host cell-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0007049-&&-cell cycle-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0010508-&&-positive regulation of autophagy|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005776-&&-autophagosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM21			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus	TRIM21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM21	0.42254177	0.08803553	90	4	FALSE	TRIM21	TRIM21	181.6477273	0	89	0	0.77222835	FALSE	1	TRIM21	576204	0.04600732
788536	taxon:9606	2.51142272	0.00242263	177487	1902	secreted phosphoprotein 1	gene	biological_process-&-1&-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0031214-&&-biomineral tissue development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0046697-&&-decidualization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0007566-&&-embryo implantation-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0033280-&&-response to vitamin D-%%-GO:0007155-&&-cell adhesion-%%-GO:0048685-&&-negative regulation of collateral sprouting of intact axon in response to injury|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0005125-&&-cytokine activity	G:9606:SPP1	SPP1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	SPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPP1	0.39818068	0.01797753	90	4	FALSE	SPP1	SPP1	71.26666667	0	90	0	0.74809621	FALSE	0	SPP1	3142726	0.02367473
788950	taxon:9606	2.35402552	2.86E-04	176547	1902	ribonucleic acid export 1	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0001650-&&-fibrillar center-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003723-&&-RNA binding	G:9606:RAE1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A	RAE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAE1	0.42480423	0.08714107	90	4	FALSE	RAE1	RAE1	148.6444444	0	90	0	0.77432908	FALSE	0	RAE1	436516	0.03685791
789034	taxon:9606	2.42004096	3.78E-04	176319	1902	transformation/transcription domain associated protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016573-&&-histone acetylation-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0016310-&&-phosphorylation-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0000125-&&-PCAF complex-%%-GO:0000812-&&-Swr1 complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0003712-&&-transcription cofactor activity	G:9606:TRRAP			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	TRRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRRAP	0.41321615	0.13657928	90	4	FALSE	TRRAP	TRRAP	131.7888889	0	90	0	0.76332651	FALSE	0	TRRAP	521954	0.03616295
789389	taxon:9606	2.33354341	2.91E-04	175593	1902	PDZ and LIM domain 7	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007411-&&-axon guidance-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001503-&&-ossification|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0001725-&&-stress fiber-%%-GO:0001726-&&-ruffle-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PDLIM7				PDLIM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDLIM7	0.42853285	0.10636704	90	4	FALSE	PDLIM7	PDLIM7	149.6111111	0	90	0	0.77774277	FALSE	0	PDLIM7	512728	0.03599947
789672	taxon:9606	2.31400662	6.11E-04	174920	1902	HCLS1 associated protein X-1	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030854-&&-positive regulation of granulocyte differentiation|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005667-&&-transcription factor complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000932-&&-P-body-%%-GO:0030027-&&-lamellipodium-%%-GO:0005739-&&-mitochondrion-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:HAX1				HAX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAX1	0.43215088	0.05593009	90	4	FALSE	HAX1	HAX1	140.7555556	0	90	0	0.7809989	FALSE	0	HAX1	728052	0.03290698
790292	taxon:9606	2.51095006	2.50E-04	173411	1902	bromodomain containing 4	gene	biological_process-&-1&-GO:1901407-&&-regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:BRD4				BRD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD4	0.39825563	0.17503121	90	4	FALSE	BRD4	BRD4	161.1666667	0	90	0	0.74817499	FALSE	0	BRD4	436514	0.05283335
791958	taxon:9606	2.30833465	4.75E-04	182805	1902	solute carrier family 25 member 6	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0006915-&&-apoptotic process-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0055085-&&-transmembrane transport-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0046732-&&-active induction of host immune response by virus-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0015867-&&-ATP transport-%%-GO:0015866-&&-ADP transport|cellular_component-&-1&-GO:0005744-&&-mitochondrial inner membrane presequence translocase complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015207-&&-adenine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005471-&&-ATP:ADP antiporter activity	G:9606:SLC25A6			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05016-&&-Huntington disease-%%-hsa04218-&&-Cellular senescence-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SLC25A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A6	0.43321275	0.06766542	90	4	FALSE	SLC25A6	SLC25A6	181.8777778	0	90	0	0.78194423	FALSE	0	SLC25A6	835838	0.04217324
792477	taxon:9606	2.42161651	6.16E-04	181956	1902	BCL2 associated X, apoptosis regulator	gene	biological_process-&-1&-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0045136-&&-development of secondary sexual characteristics-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0060068-&&-vagina development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0032976-&&-release of matrix enzymes from mitochondria-%%-GO:0034644-&&-cellular response to UV-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0016032-&&-viral process-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0021854-&&-hypothalamus development-%%-GO:0006808-&&-regulation of nitrogen utilization-%%-GO:0006915-&&-apoptotic process-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:1902445-&&-regulation of mitochondrial membrane permeability involved in programmed necrotic cell death-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0048515-&&-spermatid differentiation-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0001777-&&-T cell homeostatic proliferation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0033599-&&-regulation of mammary gland epithelial cell proliferation-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048597-&&-post-embryonic camera-type eye morphogenesis-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0002904-&&-positive regulation of B cell apoptotic process-%%-GO:0009651-&&-response to salt stress-%%-GO:0048678-&&-response to axon injury-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:1902512-&&-positive regulation of apoptotic DNA fragmentation-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0001764-&&-neuron migration-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1902263-&&-apoptotic process involved in embryonic digit morphogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0046666-&&-retinal cell programmed cell death-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007281-&&-germ cell development-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0060011-&&-Sertoli cell proliferation-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0009566-&&-fertilization-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1902262-&&-apoptotic process involved in blood vessel morphogenesis-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:1990117-&&-B cell receptor apoptotic signaling pathway-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0048087-&&-positive regulation of developmental pigmentation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0060058-&&-positive regulation of apoptotic process involved in mammary gland involution-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0002352-&&-B cell negative selection-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0001822-&&-kidney development-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0002358-&&-B cell homeostatic proliferation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0005757-&&-mitochondrial permeability transition pore complex-%%-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0097136-&&-Bcl-2 family protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0097144-&&-BAX complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008289-&&-lipid binding-%%-GO:0015267-&&-channel activity-%%-GO:0051434-&&-BH3 domain binding	G:9606:BAX	BAX	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05020-&&-Prion diseases-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa04217-&&-Necroptosis-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	BAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAX	0.4129473	0.07628004	90	4	FALSE	BAX	BAX	107.5681818	0	89	0	0.76306391	FALSE	1	BAX	661428	0.02978545
787903	taxon:9606	2.4592721	7.12E-05	178636	1902	proteasome 26S subunit, non-ATPase 12	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0031595-&&-nuclear proteasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0005737-&&-cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex	G:9606:PSMD12			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD12	0.40662438	0.35578722	89	4	FALSE	PSMD12	PSMD12	148.6781609	0	88	0	0.75678798	FALSE	1	PSMD12	188974	0.04406244
787906	taxon:9606	2.40712147	1.32E-04	178635	1902	proteasome 26S subunit, non-ATPase 13	gene	biological_process-&-1&-GO:0007127-&&-meiosis I-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0022624-&&-proteasome accessory complex|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:PSMD13			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD13	0.41543396	0.33120531	89	4	FALSE	PSMD13	PSMD13	157.9775281	0	89	0	0.76547975	FALSE	0	PSMD13	269310	0.04283251
788111	taxon:9606	2.43264534	3.94E-04	178216	1902	protein tyrosine phosphatase, non-receptor type 6	gene	biological_process-&-1&-GO:0002924-&&-negative regulation of humoral immune response mediated by circulating immunoglobulin-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070527-&&-platelet aggregation-%%-GO:0050859-&&-negative regulation of B cell receptor signaling pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0030154-&&-cell differentiation-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0033277-&&-abortive mitotic cell cycle-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030220-&&-platelet formation-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0008283-&&-cell proliferation-%%-GO:0043407-&&-negative regulation of MAP kinase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0042105-&&-alpha-beta T cell receptor complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:PTPN6			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa04520-&&-Adherens junction-%%-hsa04660-&&-T cell receptor signaling pathway	PTPN6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN6	0.41107513	0.15022721	89	4	FALSE	PTPN6	PTPN6	113.8275862	0	88	0	0.76122578	FALSE	1	PTPN6	479648	0.03222101
788862	taxon:9606	2.40554593	2.66E-04	176737	1902	vitamin D (1,25- dihydroxyvitamin D3) receptor	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050892-&&-intestinal absorption-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0038183-&&-bile acid signaling pathway-%%-GO:0007595-&&-lactation-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0046697-&&-decidualization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060058-&&-positive regulation of apoptotic process involved in mammary gland involution-%%-GO:0006816-&&-calcium ion transport-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0060558-&&-regulation of calcidiol 1-monooxygenase activity-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0001501-&&-skeletal system development-%%-GO:0070561-&&-vitamin D receptor signaling pathway-%%-GO:0010980-&&-positive regulation of vitamin D 24-hydroxylase activity-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060745-&&-mammary gland branching involved in pregnancy|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008434-&&-calcitriol receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0070644-&&-vitamin D response element binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:1902098-&&-calcitriol binding-%%-GO:0038186-&&-lithocholic acid receptor activity-%%-GO:0003677-&&-DNA binding-%%-GO:1902121-&&-lithocholic acid binding	G:9606:VDR	VDR	TRUE	KEGG-&-1&-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05152-&&-Tuberculosis-%%-hsa04978-&&-Mineral absorption	VDR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDR	0.41570605	0.13124833	89	4	FALSE	VDR	VDR	130.7701149	0	88	0	0.76574235	FALSE	1	VDR	426056	0.03515035
789324	taxon:9606	2.37687096	2.93E-04	175732	1902	receptor interacting serine/threonine kinase 1	gene	biological_process-&-1&-GO:0097527-&&-necroptotic signaling pathway-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:1901026-&&-ripoptosome assembly involved in necroptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0070231-&&-T cell apoptotic process-%%-GO:0070926-&&-regulation of ATP:ADP antiporter activity-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0070266-&&-necroptotic process-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0010940-&&-positive regulation of necrotic cell death-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0060545-&&-positive regulation of necroptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1905206-&&-positive regulation of hydrogen peroxide-induced cell death-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0097343-&&-ripoptosome assembly-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0045121-&&-membrane raft-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0097342-&&-ripoptosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0070513-&&-death domain binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004871-&&-signal transducer activity	G:9606:RIPK1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis-%%-hsa05163-&&-Human cytomegalovirus infection	RIPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK1	0.4207212	0.17348303	89	4	FALSE	RIPK1	RIPK1	134.862069	0	88	0	0.77052151	FALSE	1	RIPK1	429088	0.03468083
789499	taxon:9606	2.51709469	1.99E-04	175332	1902	centrosomal protein 135	gene	biological_process-&-1&-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:CEP135				CEP135	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP135	0.39728343	0.1195097	89	4	FALSE	CEP135	CEP135	85.17977528	0	89	0	0.74715088	FALSE	0	CEP135	284394	0.02813819
789636	taxon:9606	2.38427604	3.93E-04	175011	1902	TRK-fused gene	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TFG			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	TFG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFG	0.41941452	0.08233093	89	4	FALSE	TFG	TFG	149.7126437	0	88	0	0.76928733	FALSE	1	TFG	545342	0.03904626
790400	taxon:9606	2.45942965	2.37E-04	173116	1902	tripartite motif containing 29	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM29				TRIM29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM29	0.40659833	0.05506549	89	4	FALSE	TRIM29	TRIM29	147.8735632	0	88	0	0.75676172	FALSE	1	TRIM29	411294	0.04377693
790574	taxon:9606	2.34488735	1.12E-04	172095	1902	proline, glutamate and leucine rich protein 1	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PELP1				PELP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PELP1	0.42645972	0.22139939	89	4	FALSE	PELP1	PELP1	246.5730337	0	89	0	0.77585211	FALSE	0	PELP1	346416	0.06027207
791661	taxon:9606	2.41862297	3.88E-04	167558	1902	microtubule associated protein 1 light chain 3 beta	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0000422-&&-mitophagy-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0005776-&&-autophagosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0005930-&&-axoneme-%%-GO:0005739-&&-mitochondrion-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:MAP1LC3B			KEGG-&-1&-hsa04216-&&-Ferroptosis	MAP1LC3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1LC3B	0.41345841	0.06690501	89	4	FALSE	MAP1LC3B	MAP1LC3B	104.2696629	0	89	0	0.76356284	FALSE	0	MAP1LC3B	468374	0.02863964
792532	taxon:9606	2.34725067	6.48E-04	181847	1902	calpain 1	gene	biological_process-&-1&-GO:0097264-&&-self proteolysis-%%-GO:0006508-&&-proteolysis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0060056-&&-mammary gland involution-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity	G:9606:CAPN1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CAPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPN1	0.42603034	0.06843718	89	4	FALSE	CAPN1	CAPN1	137.4719101	0	89	0	0.77545822	FALSE	0	CAPN1	733948	0.03384908
787233	taxon:9606	2.3746652	1.46E-04	179821	1902	eukaryotic translation initiation factor 3 subunit E	gene	biological_process-&-1&-GO:0045947-&&-negative regulation of translational initiation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006413-&&-translational initiation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0000785-&&-chromatin-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0003723-&&-RNA binding	G:9606:EIF3E			KEGG-&-1&-hsa05160-&&-Hepatitis C-%%-hsa03013-&&-RNA transport	EIF3E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3E	0.421112	0.17868339	88	4	FALSE	EIF3E	EIF3E	177.4659091	0	88	0	0.77088913	FALSE	0	EIF3E	327074	0.0455216
787407	taxon:9606	2.45596345	1.24E-04	179482	1902	nibrin	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0090656-&&-t-circle formation-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0001832-&&-blastocyst growth-%%-GO:0030174-&&-regulation of DNA-dependent DNA replication initiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000732-&&-strand displacement-%%-GO:0008283-&&-cell proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0000723-&&-telomere maintenance-%%-GO:0045190-&&-isotype switching-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0031860-&&-telomeric 3' overhang formation|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0016605-&&-PML body-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0030870-&&-Mre11 complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:NBN			KEGG-&-1&-hsa03440-&&-Homologous recombination-%%-hsa04218-&&-Cellular senescence	NBN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBN	0.40717218	0.17763845	88	4	FALSE	NBN	NBN	172.875	0	88	0	0.75733943	FALSE	0	NBN	302030	0.05079742
787456	taxon:9606	2.35181976	4.25E-04	179403	1902	mitogen-activated protein kinase kinase kinase 5	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0007254-&&-JNK cascade-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042060-&&-wound healing-%%-GO:0016032-&&-viral process-%%-GO:1902170-&&-cellular response to reactive nitrogen species-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0002931-&&-response to ischemia-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:1902911-&&-protein kinase complex-%%-GO:1990604-&&-IRE1-TRAF2-ASK1 complex-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:MAP3K5			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04530-&&-Tight junction-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	MAP3K5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K5	0.42520265	0.09931601	88	4	FALSE	MAP3K5	MAP3K5	149.2790698	0	87	0	0.77469671	FALSE	1	MAP3K5	611718	0.03689309
787870	taxon:9606	2.38270049	1.06E-04	178668	1902	proteasome subunit alpha 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0000932-&&-P-body-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA4			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA4	0.41969186	0.34117647	88	4	FALSE	PSMA4	PSMA4	162.9534884	0	87	0	0.76954992	FALSE	1	PSMA4	248960	0.04222084
787878	taxon:9606	2.38207027	1.68E-04	178661	1902	proteasome subunit beta 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0002862-&&-negative regulation of inflammatory response to antigenic stimulus-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB4	PSMB4	TRUE	KEGG-&-1&-hsa03050-&&-Proteasome	PSMB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB4	0.4198029	0.31922675	88	4	FALSE	PSMB4	PSMB4	146.3636364	0	88	0	0.76965496	FALSE	0	PSMB4	318002	0.03792492
787968	taxon:9606	2.3199937	1.92E-04	178491	1902	poly(rC) binding protein 2	gene	biological_process-&-1&-GO:0016071-&&-mRNA metabolic process-%%-GO:0045087-&&-innate immune response-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0051607-&&-defense response to virus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:1990829-&&-C-rich single-stranded DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PCBP2			KEGG-&-1&-hsa04216-&&-Ferroptosis	PCBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBP2	0.43103565	0.20273598	88	4	FALSE	PCBP2	PCBP2	234.2906977	0	87	0	0.78000105	FALSE	1	PCBP2	375982	0.05517916
788072	taxon:9606	2.45296991	2.48E-05	178281	1902	ribosomal protein L32	gene	biological_process-&-1&-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0097421-&&-liver regeneration-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL32			KEGG-&-1&-hsa03010-&&-Ribosome	RPL32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL32	0.40766909	0.53683386	88	4	FALSE	RPL32	RPL32	234.8409091	0	88	0	0.75783835	FALSE	0	RPL32	127570	0.06840691
788375	taxon:9606	2.27887191	2.42E-04	177781	1902	Sjogren syndrome antigen B	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SSB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus	SSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSB	0.43881361	0.13351573	88	4	FALSE	SSB	SSB	234.1395349	0	87	0	0.78685468	FALSE	1	SSB	501928	0.05197705
788390	taxon:9606	2.36726012	6.25E-04	177749	1902	signal transducer and activator of transcription 5A	gene	biological_process-&-1&-GO:0006573-&&-valine metabolic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0007595-&&-lactation-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0006549-&&-isoleucine metabolic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000255-&&-allantoin metabolic process-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0038161-&&-prolactin signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:STAT5A			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis	STAT5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT5A	0.42242928	0.11709986	88	4	FALSE	STAT5A	STAT5A	129.7325581	0	87	0	0.77212331	FALSE	1	STAT5A	733804	0.03292015
789535	taxon:9606	2.38049472	1.36E-04	175237	1902	DDB1 and CUL4 associated factor 1	gene	biological_process-&-1&-GO:1990245-&&-histone H2A-T120 phosphorylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035212-&&-cell competition in a multicellular organism-%%-GO:0016032-&&-viral process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030183-&&-B cell differentiation-%%-GO:0033151-&&-V(D)J recombination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:1990244-&&-histone kinase activity (H2A-T120 specific)-%%-GO:0005524-&&-ATP binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding	G:9606:DCAF1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection	DCAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF1	0.42008075	0.1625171	88	4	FALSE	DCAF1	DCAF1	205.5697674	0	87	0	0.76991755	FALSE	1	DCAF1	375290	0.05293498
789673	taxon:9606	2.58200725	2.50E-04	174923	1902	translocase of outer mitochondrial membrane 40	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0030150-&&-protein import into mitochondrial matrix-%%-GO:0006626-&&-protein targeting to mitochondrion|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0046930-&&-pore complex|molecular_function-&-1&-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0015266-&&-protein channel activity-%%-GO:0015288-&&-porin activity	G:9606:TOMM40			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	TOMM40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM40	0.38729558	0.07001045	88	4	FALSE	TOMM40	TOMM40	76.67045455	0	88	0	0.73633213	FALSE	0	TOMM40	300644	0.02937385
789694	taxon:9606	2.34662045	1.79E-04	174879	1902	coactivator associated arginine methyltransferase 1	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0003420-&&-regulation of growth plate cartilage chondrocyte proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0034970-&&-histone H3-R2 methylation-%%-GO:0034971-&&-histone H3-R17 methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000171-&&-negative regulation of dendrite development-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007568-&&-aging-%%-GO:0016571-&&-histone methylation-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0051591-&&-response to cAMP-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0060350-&&-endochondral bone morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:1902415-&&-regulation of mRNA binding-%%-GO:0071168-&&-protein localization to chromatin-%%-GO:0045600-&&-positive regulation of fat cell differentiation|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0035642-&&-histone methyltransferase activity (H3-R17 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008276-&&-protein methyltransferase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CARM1			KEGG-&-1&-hsa01522-&&-Endocrine resistance	CARM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARM1	0.42614476	0.1700627	88	4	FALSE	CARM1	CARM1	212.8863636	0	88	0	0.77556326	FALSE	0	CARM1	410146	0.05215411
790489	taxon:9606	2.35418308	9.93E-05	172715	1902	NOC2 like nucleolar associated transcriptional repressor	gene	biological_process-&-1&-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034644-&&-cellular response to UV-%%-GO:0031497-&&-chromatin assembly-%%-GO:0032066-&&-nucleolus to nucleoplasm transport|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0030690-&&-Noc1p-Noc2p complex-%%-GO:0030691-&&-Noc2p-Noc3p complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:NOC2L				NOC2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOC2L	0.4247758	0.23772205	88	4	FALSE	NOC2L	NOC2L	239.0227273	0	88	0	0.77430282	FALSE	0	NOC2L	318590	0.05907069
790768	taxon:9606	2.61131243	1.25E-04	171280	1902	leucine zipper protein 4	gene	biological_process-&-1&-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LUZP4				LUZP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUZP4	0.3829492	0.09028728	88	4	FALSE	LUZP4	LUZP4	121.8255814	0	87	0	0.73144793	FALSE	1	LUZP4	254402	0.04937381
791214	taxon:9606	2.53710414	2.13E-04	169718	1902	centromere protein J	gene	biological_process-&-1&-GO:0046785-&&-microtubule polymerization-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0061511-&&-centriole elongation-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051301-&&-cell division-%%-GO:0044458-&&-motile cilium assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CENPJ				CENPJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPJ	0.39415016	0.07497388	88	4	FALSE	CENPJ	CENPJ	84.60227273	0	88	0	0.74381598	FALSE	0	CENPJ	283216	0.02931432
792072	taxon:9606	2.25618402	0.00141875	182663	1902	clusterin	gene	biological_process-&-1&-GO:1902847-&&-regulation of neuronal signal transduction-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1903573-&&-negative regulation of response to endoplasmic reticulum stress-%%-GO:0017038-&&-protein import-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0006956-&&-complement activation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0050821-&&-protein stabilization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1900221-&&-regulation of beta-amyloid clearance-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0051788-&&-response to misfolded protein-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:1905895-&&-negative regulation of cellular response to tunicamycin-%%-GO:0001774-&&-microglial cell activation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032286-&&-central nervous system myelin maintenance-%%-GO:0061518-&&-microglial cell proliferation-%%-GO:1905907-&&-negative regulation of amyloid fibril formation-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:1902949-&&-positive regulation of tau-protein kinase activity-%%-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:1905892-&&-negative regulation of cellular response to thapsigargin-%%-GO:1902998-&&-positive regulation of neurofibrillary tangle assembly-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:1902430-&&-negative regulation of beta-amyloid formation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0009615-&&-response to virus-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0042583-&&-chromaffin granule-%%-GO:0071944-&&-cell periphery-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0097440-&&-apical dendrite-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0034366-&&-spherical high-density lipoprotein particle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CLU			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	CLU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLU	0.44322626	0.06073871	88	4	FALSE	CLU	CLU	152.9534884	0	87	0	0.790636	FALSE	1	CLU	1370184	0.03300266
792164	taxon:9606	2.41326611	5.72E-04	182492	1902	Fas cell surface death receptor	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0003014-&&-renal system process-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0097049-&&-motor neuron apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045619-&&-regulation of lymphocyte differentiation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0048536-&&-spleen development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007165-&&-signal transduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0006925-&&-inflammatory cell apoptotic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0019724-&&-B cell mediated immunity-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0050869-&&-negative regulation of B cell activation-%%-GO:0070230-&&-positive regulation of lymphocyte apoptotic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0045637-&&-regulation of myeloid cell differentiation-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016604-&&-nuclear body-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0009986-&&-cell surface-%%-GO:0031264-&&-death-inducing signaling complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0043120-&&-tumor necrosis factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:FAS	FAS	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAS	0.41437618	0.07770178	88	4	FALSE	FAS	FAS	108.372093	0	87	0	0.76445565	FALSE	1	FAS	705286	0.02965913
792255	taxon:9606	2.36064282	2.45E-04	182340	1902	ATR serine/threonine kinase	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006260-&&-DNA replication-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0090399-&&-replicative senescence-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:1904884-&&-positive regulation of telomerase catalytic core complex assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006281-&&-DNA repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0007049-&&-cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0097694-&&-establishment of RNA localization to telomere-%%-GO:0097695-&&-establishment of macromolecular complex localization to telomere|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005694-&&-chromosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0032407-&&-MutSalpha complex binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0005524-&&-ATP binding	G:9606:ATR	ATR	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa05165-&&-Human papillomavirus infection	ATR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATR	0.42361343	0.11627907	88	4	FALSE	ATR	ATR	149.3139535	0	87	0	0.7732262	FALSE	1	ATR	434240	0.0372947
792272	taxon:9606	2.36206082	2.39E-04	182308	1902	cell division cycle 27	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:CDC27	CDC27	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC27	0.42335912	0.13296854	88	4	FALSE	CDC27	CDC27	146.6162791	0	87	0	0.77298986	FALSE	1	CDC27	428840	0.03670622
792307	taxon:9606	2.52654798	1.18E-04	182251	1902	centromere protein A	gene	biological_process-&-1&-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0016032-&&-viral process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051382-&&-kinetochore assembly|cellular_component-&-1&-GO:0000778-&&-condensed nuclear chromosome kinetochore-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000939-&&-condensed chromosome inner kinetochore-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:CENPA				CENPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPA	0.39579696	0.27140903	88	4	FALSE	CENPA	CENPA	192.1046512	0	87	0	0.74557534	FALSE	1	CENPA	246598	0.06464427
792507	taxon:9606	2.47061604	2.67E-04	165507	1902	HAUS augmin like complex subunit 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:HAUS1				HAUS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS1	0.40475735	0.09603283	88	4	FALSE	HAUS1	HAUS1	112.4651163	0	87	0	0.75489733	FALSE	1	HAUS1	396168	0.03391911
793235	taxon:9606	2.49346148	2.35E-04	164096	1902	spindle and centriole associated protein 1	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0046599-&&-regulation of centriole replication-%%-GO:0051301-&&-cell division-%%-GO:0051310-&&-metaphase plate congression|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPICE1				SPICE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPICE1	0.40104891	0.09090909	88	4	FALSE	SPICE1	SPICE1	90.42045455	0	88	0	0.75108975	FALSE	0	SPICE1	312940	0.02843414
793304	taxon:9606	2.3565464	3.07E-04	180346	1902	host cell factor C1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0019046-&&-release from viral latency-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0007049-&&-cell cycle-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0070461-&&-SAGA-type complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0071339-&&-MLL1 complex-%%-GO:0016020-&&-membrane-%%-GO:0000123-&&-histone acetyltransferase complex|molecular_function-&-1&-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HCFC1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	HCFC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCFC1	0.4243498	0.10369357	88	4	FALSE	HCFC1	HCFC1	162.9069767	0	87	0	0.77390893	FALSE	1	HCFC1	517648	0.04042206
787073	taxon:9606	2.23176304	9.16E-04	180119	1902	insulin like growth factor 1 receptor	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006955-&&-immune response-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0051389-&&-inactivation of MAPKK activity-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0051262-&&-protein tetramerization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0035867-&&-alphav-beta3 integrin-IGF-1-IGF1R complex-%%-GO:0043235-&&-receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0005010-&&-insulin-like growth factor-activated receptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043559-&&-insulin binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005520-&&-insulin-like growth factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:IGF1R	IGF1R	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa01522-&&-Endocrine resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma	IGF1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF1R	0.44807624	0.14453782	87	4	FALSE	IGF1R	IGF1R	184.7058824	0	86	0	0.79470616	FALSE	1	IGF1R	1010106	0.03851561
787659	taxon:9606	2.32298724	1.97E-04	179000	1902	nuclear mitotic apparatus protein 1	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0061673-&&-mitotic spindle astral microtubule-%%-GO:0097431-&&-mitotic spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0030425-&&-dendrite-%%-GO:0005813-&&-centrosome-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:NUMA1				NUMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUMA1	0.4304802	0.12777332	87	4	FALSE	NUMA1	NUMA1	213.954023	0	87	0	0.77950213	FALSE	0	NUMA1	417516	0.05053887
787763	taxon:9606	2.38490625	2.66E-04	178826	1902	mediator complex subunit 1	gene	biological_process-&-1&-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2001141-&&-regulation of RNA biosynthetic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0007595-&&-lactation-%%-GO:0006590-&&-thyroid hormone generation-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0001889-&&-liver development-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:0060745-&&-mammary gland branching involved in pregnancy-%%-GO:0003406-&&-retinal pigment epithelium development-%%-GO:0007420-&&-brain development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0048821-&&-erythrocyte development-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0070318-&&-positive regulation of G0 to G1 transition-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0060750-&&-epithelial cell proliferation involved in mammary gland duct elongation-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0060335-&&-positive regulation of interferon-gamma-mediated signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0002154-&&-thyroid hormone mediated signaling pathway-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048822-&&-enucleate erythrocyte development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0045665-&&-negative regulation of neuron differentiation|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0050693-&&-LBD domain binding-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0036033-&&-mediator complex binding	G:9606:MED1			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance	MED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED1	0.41930369	0.20756303	87	4	FALSE	MED1	MED1	138.3882353	0	86	0	0.76918229	FALSE	1	MED1	425246	0.03586741
787881	taxon:9606	2.3948322	1.06E-04	178662	1902	proteasome subunit beta 3	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0019774-&&-proteasome core complex, beta-subunit complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB3			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB3	0.41756579	0.34985994	87	4	FALSE	PSMB3	PSMB3	161.1882353	0	86	0	0.76752797	FALSE	1	PSMB3	267436	0.04253489
788077	taxon:9606	2.55616827	3.27E-05	178278	1902	ribosomal protein L35a	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:RPL35A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL35A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL35A	0.39121055	0.57925688	87	4	FALSE	RPL35A	RPL35A	177.6206897	0	87	0	0.74063862	FALSE	0	RPL35A	86928	0.06372773
788166	taxon:9606	2.40617615	3.82E-04	178137	1902	RAD51 recombinase	gene	biological_process-&-1&-GO:0000730-&&-DNA recombinase assembly-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0031297-&&-replication fork processing-%%-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0072757-&&-cellular response to camptothecin-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0000732-&&-strand displacement-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:1904631-&&-response to glucoside-%%-GO:0042493-&&-response to drug-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1990426-&&-mitotic recombination-dependent replication fork processing-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0051106-&&-positive regulation of DNA ligation-%%-GO:0006312-&&-mitotic recombination-%%-GO:0042148-&&-strand invasion-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0072719-&&-cellular response to cisplatin-%%-GO:0006310-&&-DNA recombination-%%-GO:0009636-&&-response to toxic substance-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:1990414-&&-replication-born double-strand break repair via sister chromatid exchange-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0006281-&&-DNA repair-%%-GO:0010165-&&-response to X-ray|cellular_component-&-1&-GO:0000793-&&-condensed chromosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005739-&&-mitochondrion-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0000150-&&-recombinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004520-&&-endodeoxyribonuclease activity	G:9606:RAD51			KEGG-&-1&-hsa05212-&&-Pancreatic cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway	RAD51	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD51	0.41559717	0.09103641	87	4	FALSE	RAD51	RAD51	126.4941177	0	86	0	0.76563731	FALSE	1	RAD51	466286	0.03418064
788204	taxon:9606	2.35701906	2.57E-04	178091	1902	RNA binding motif protein 4	gene	biological_process-&-1&-GO:0097167-&&-circadian regulation of translation-%%-GO:0006396-&&-RNA processing-%%-GO:0032055-&&-negative regulation of translation in response to stress-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0002190-&&-cap-independent translational initiation-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0008380-&&-RNA splicing-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0002192-&&-IRES-dependent translational initiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0030154-&&-cell differentiation-%%-GO:0045947-&&-negative regulation of translational initiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0097158-&&-pre-mRNA intronic pyrimidine-rich binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0097157-&&-pre-mRNA intronic binding	G:9606:RBM4				RBM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM4	0.42426471	0.17401764	87	4	FALSE	RBM4	RBM4	214.3563218	0	87	0	0.77383016	FALSE	0	RBM4	463300	0.05336413
788656	taxon:9606	2.44698283	9.10E-04	177241	1902	transforming growth factor beta receptor 2	gene	biological_process-&-1&-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0002651-&&-positive regulation of tolerance induction to self antigen-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0007420-&&-brain development-%%-GO:0002663-&&-positive regulation of B cell tolerance induction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0043627-&&-response to estrogen-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007566-&&-embryo implantation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0009749-&&-response to glucose-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0042060-&&-wound healing-%%-GO:0003274-&&-endocardial cushion fusion-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0003186-&&-tricuspid valve morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:1905315-&&-cell proliferation involved in endocardial cushion morphogenesis-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0001568-&&-blood vessel development-%%-GO:0007507-&&-heart development-%%-GO:0048565-&&-digestive tract development-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0003430-&&-growth plate cartilage chondrocyte growth-%%-GO:0001570-&&-vasculogenesis-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0060434-&&-bronchus morphogenesis-%%-GO:0007568-&&-aging-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007369-&&-gastrulation-%%-GO:0002666-&&-positive regulation of T cell tolerance induction-%%-GO:1990086-&&-lens fiber cell apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0060440-&&-trachea formation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0060463-&&-lung lobe morphogenesis-%%-GO:0060443-&&-mammary gland morphogenesis-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0051138-&&-positive regulation of NK T cell differentiation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043415-&&-positive regulation of skeletal muscle tissue regeneration-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0070723-&&-response to cholesterol-%%-GO:0060021-&&-palate development-%%-GO:0007584-&&-response to nutrient-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0007182-&&-common-partner SMAD protein phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0003214-&&-cardiac left ventricle morphogenesis|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005901-&&-caveola-%%-GO:0070022-&&-transforming growth factor beta receptor complex-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0005026-&&-transforming growth factor beta receptor activity, type II-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity	G:9606:TGFBR2			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05210-&&-Colorectal cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa04520-&&-Adherens junction-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TGFBR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBR2	0.40866654	0.0719888	87	4	FALSE	TGFBR2	TGFBR2	94.11764706	0	86	0	0.7588362	FALSE	1	TGFBR2	991830	0.02736193
788896	taxon:9606	2.36899323	3.65E-04	176653	1902	YES proto-oncogene 1, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0015758-&&-glucose transport-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0030154-&&-cell differentiation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:YES1			KEGG-&-1&-hsa04520-&&-Adherens junction	YES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YES1	0.42212024	0.07310924	87	4	FALSE	YES1	YES1	131.8	0	86	0	0.77183446	FALSE	1	YES1	544028	0.03350787
789207	taxon:9606	2.40223728	1.65E-04	176000	1902	Y-box binding protein 3	gene	biological_process-&-1&-GO:1902219-&&-negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress-%%-GO:0009409-&&-response to cold-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071474-&&-cellular hyperosmotic response-%%-GO:0046622-&&-positive regulation of organ growth-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0008584-&&-male gonad development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0009566-&&-fertilization-%%-GO:2000767-&&-positive regulation of cytoplasmic translation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:YBX3			KEGG-&-1&-hsa04530-&&-Tight junction	YBX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBX3	0.41627861	0.15183106	87	4	FALSE	YBX3	YBX3	221.5057471	0	87	0	0.76629379	FALSE	0	YBX3	430958	0.05910979
789619	taxon:9606	2.35922483	1.05E-04	175046	1902	heterogeneous nuclear ribonucleoprotein D like	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPDL				HNRNPDL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPDL	0.42386804	0.28281208	87	4	FALSE	HNRNPDL	HNRNPDL	233.0229885	0	87	0	0.77346253	FALSE	0	HNRNPDL	253536	0.0582966
790155	taxon:9606	2.42461005	1.98E-04	173751	1902	apoptotic chromatin condensation inducer 1	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0045657-&&-positive regulation of monocyte differentiation-%%-GO:0030263-&&-apoptotic chromosome condensation-%%-GO:0006397-&&-mRNA processing-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0030218-&&-erythrocyte differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0061574-&&-ASAP complex|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:ACIN1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	ACIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACIN1	0.41243746	0.2183908	87	4	FALSE	ACIN1	ACIN1	210.7126437	0	87	0	0.76256499	FALSE	0	ACIN1	366696	0.05845357
790185	taxon:9606	2.3864818	2.31E-04	173696	1902	nuclear receptor coactivator 6	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0007420-&&-brain development-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0006310-&&-DNA recombination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006260-&&-DNA replication-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:NCOA6				NCOA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA6	0.41902687	0.17142857	87	4	FALSE	NCOA6	NCOA6	156.0470588	0	86	0	0.7689197	FALSE	1	NCOA6	397190	0.04069778
791826	taxon:9606	2.52843863	2.04E-04	166668	1902	polycomb group ring finger 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PCGF1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PCGF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCGF1	0.395501	0.14705882	87	4	FALSE	PCGF1	PCGF1	146.6352941	0	86	0	0.74526023	FALSE	1	PCGF1	402700	0.04942207
792061	taxon:9606	2.35402552	3.82E-04	182672	1902	Bruton tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0098761-&&-cellular response to interleukin-7-%%-GO:0007498-&&-mesoderm development-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0001812-&&-positive regulation of type I hypersensitivity-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042113-&&-B cell activation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0002553-&&-histamine secretion by mast cell-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002902-&&-regulation of B cell apoptotic process-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048469-&&-cell maturation-%%-GO:0001805-&&-positive regulation of type III hypersensitivity-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0071226-&&-cellular response to molecule of fungal origin-%%-GO:0002344-&&-B cell affinity maturation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0002721-&&-regulation of B cell cytokine production|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042629-&&-mast cell granule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:BTK			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05340-&&-Primary immunodeficiency	BTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTK	0.42480423	0.11036415	87	4	FALSE	BTK	BTK	135.8235294	0	86	0	0.77432908	FALSE	1	BTK	502828	0.03371945
792069	taxon:9606	2.40822436	3.12E-04	182666	1902	bystin like	gene	biological_process-&-1&-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0007565-&&-female pregnancy-%%-GO:0008283-&&-cell proliferation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:BYSL				BYSL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BYSL	0.4152437	0.0837535	87	4	FALSE	BYSL	BYSL	132.8705882	0	86	0	0.76529594	FALSE	1	BYSL	484156	0.03584316
792335	taxon:9606	2.27241216	4.36E-04	182208	1902	checkpoint kinase 1	gene	biological_process-&-1&-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0006260-&&-DNA replication-%%-GO:0035407-&&-histone H3-T11 phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010767-&&-regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0006281-&&-DNA repair-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0045839-&&-negative regulation of mitotic nuclear division-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0046602-&&-regulation of mitotic centrosome separation-%%-GO:0007049-&&-cell cycle-%%-GO:0090399-&&-replicative senescence|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000794-&&-condensed nuclear chromosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035402-&&-histone kinase activity (H3-T11 specific)-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CHEK1	CHEK1	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence	CHEK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHEK1	0.44006101	0.13124833	87	4	FALSE	CHEK1	CHEK1	187.9885058	0	87	0	0.78793131	FALSE	0	CHEK1	581314	0.04133836
792583	taxon:9606	2.42744604	4.59E-04	181770	1902	CD4 molecule	gene	biological_process-&-1&-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061024-&&-membrane organization-%%-GO:0001816-&&-cytokine production-%%-GO:0006955-&&-immune response-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:0030260-&&-entry into host cell-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0032507-&&-maintenance of protein location in cell-%%-GO:0030217-&&-T cell differentiation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0035397-&&-helper T cell enhancement of adaptive immune response-%%-GO:0045058-&&-T cell selection-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0006948-&&-induction by virus of host cell-cell fusion-%%-GO:0033280-&&-response to vitamin D-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0050863-&&-regulation of T cell activation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005769-&&-early endosome-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0042289-&&-MHC class II protein binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019865-&&-immunoglobulin binding-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004872-&&-receptor activity-%%-GO:0015026-&&-coreceptor activity	G:9606:CD4	CD4	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04660-&&-T cell receptor signaling pathway	CD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD4	0.4119556	0.08235294	87	4	FALSE	CD4	CD4	127.7294118	0	86	0	0.76209233	FALSE	1	CD4	592322	0.03587276
792800	taxon:9606	2.34961399	2.35E-04	181348	1902	eukaryotic translation initiation factor 4 gamma 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0007005-&&-mitochondrion organization-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0002191-&&-cap-dependent translational initiation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0006412-&&-translation-%%-GO:0034645-&&-cellular macromolecule biosynthetic process-%%-GO:0080135-&&-regulation of cellular response to stress-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0001662-&&-behavioral fear response-%%-GO:0060964-&&-regulation of gene silencing by miRNA-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0016032-&&-viral process-%%-GO:0032502-&&-developmental process-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:1905537-&&-positive regulation of eukaryotic translation initiation factor 4F complex assembly-%%-GO:1905612-&&-positive regulation of mRNA cap binding-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:1905606-&&-regulation of presynapse assembly-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0006413-&&-translational initiation-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:1905696-&&-regulation of polysome binding-%%-GO:2000507-&&-positive regulation of energy homeostasis-%%-GO:1905618-&&-positive regulation of miRNA mediated inhibition of translation-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:EIF4G1			KEGG-&-1&-hsa05416-&&-Viral myocarditis-%%-hsa03013-&&-RNA transport	EIF4G1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4G1	0.42560182	0.13766373	87	4	FALSE	EIF4G1	EIF4G1	186.9310345	0	87	0	0.77506433	FALSE	0	EIF4G1	393492	0.04604497
787468	taxon:9606	2.39861352	3.65E-04	179377	1902	O-6-methylguanine-DNA methyltransferase	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0051593-&&-response to folic acid-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006306-&&-DNA methylation-%%-GO:0042493-&&-response to drug-%%-GO:0009636-&&-response to toxic substance-%%-GO:2000781-&&-positive regulation of double-strand break repair-%%-GO:0045471-&&-response to ethanol-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0006307-&&-DNA dealkylation involved in DNA repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:0003908-&&-methylated-DNA-[protein]-cysteine S-methyltransferase activity-%%-GO:0008168-&&-methyltransferase activity	G:9606:MGMT				MGMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGMT	0.41690751	0.11044177	86	4	FALSE	MGMT	MGMT	176.1547619	0	85	0	0.76689775	FALSE	1	MGMT	638026	0.04688986
788148	taxon:9606	2.4926737	2.38E-04	178162	1902	RAB2A, member RAS oncogene family	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0019003-&&-GDP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:RAB2A			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway	RAB2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB2A	0.40117565	0.09150889	86	4	FALSE	RAB2A	RAB2A	109.1071429	0	85	0	0.75122105	FALSE	1	RAB2A	335814	0.03449406
789170	taxon:9606	2.33700961	3.26E-04	176053	1902	metastasis associated 1	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:1902499-&&-positive regulation of protein autoubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0006302-&&-double-strand break repair-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0016575-&&-histone deacetylation-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001047-&&-core promoter binding	G:9606:MTA1				MTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTA1	0.42789726	0.13597811	86	4	FALSE	MTA1	MTA1	162.5116279	0	86	0	0.77716506	FALSE	0	MTA1	579934	0.03910289
789865	taxon:9606	2.31038286	2.09E-04	174487	1902	GCN1, eIF2 alpha kinase activator homolog	gene	biological_process-&-1&-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006417-&&-regulation of translation-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:1990253-&&-cellular response to leucine starvation-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005840-&&-ribosome-%%-GO:0016020-&&-membrane-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding	G:9606:GCN1				GCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCN1	0.4328287	0.11326949	86	4	FALSE	GCN1	GCN1	229.7093023	0	86	0	0.78160286	FALSE	0	GCN1	525968	0.05333823
789957	taxon:9606	2.38537892	1.63E-04	174251	1902	UTP14A small subunit processome component	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0032040-&&-small-subunit processome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UTP14A			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	UTP14A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP14A	0.41922061	0.13187415	86	4	FALSE	UTP14A	UTP14A	148.6511628	0	86	0	0.76910351	FALSE	0	UTP14A	316530	0.03865788
789990	taxon:9606	2.5389948	1.71E-04	174176	1902	centrosomal protein 162	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005879-&&-axonemal microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP162				CEP162	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP162	0.39385666	0.12612859	86	4	FALSE	CEP162	CEP162	97.41860465	0	86	0	0.74350087	FALSE	0	CEP162	273670	0.03376247
792241	taxon:9606	2.29888136	2.94E-04	182367	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	gene	biological_process-&-1&-GO:0006754-&&-ATP biosynthetic process-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000275-&&-mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0003723-&&-RNA binding	G:9606:ATP5C1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5C1	0.43499417	0.17099863	86	4	FALSE	ATP5C1	ATP5C1	190.7790698	0	86	0	0.78351977	FALSE	0	ATP5C1	583576	0.04355687
792289	taxon:9606	2.36347881	3.85E-04	182283	1902	cyclin dependent kinase 6	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0042063-&&-gliogenesis-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0051301-&&-cell division-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0010468-&&-regulation of gene expression-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0003323-&&-type B pancreatic cell development-%%-GO:0009615-&&-response to virus-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0014002-&&-astrocyte development-%%-GO:0043697-&&-cell dedifferentiation-%%-GO:0048699-&&-generation of neurons-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045656-&&-negative regulation of monocyte differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0001726-&&-ruffle-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0098770-&&-FBXO family protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK6	CDK6	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa05160-&&-Hepatitis C-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma	CDK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK6	0.42310513	0.08405049	86	4	FALSE	CDK6	CDK6	129.0714286	0	85	0	0.77275353	FALSE	1	CDK6	479484	0.0323727
792518	taxon:9606	2.35197731	3.35E-04	181857	1902	calumenin	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0033018-&&-sarcoplasmic reticulum lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CALU				CALU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALU	0.42517417	0.09466484	86	4	FALSE	CALU	CALU	151.5930233	0	86	0	0.77467045	FALSE	0	CALU	539830	0.03749935
792796	taxon:9606	2.35244998	1.26E-04	181353	1902	eukaryotic translation initiation factor 4B	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0097010-&&-eukaryotic translation initiation factor 4F complex assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0002181-&&-cytoplasmic translation|cellular_component-&-1&-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0004386-&&-helicase activity-%%-GO:0034057-&&-RNA strand-exchange activity-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0033592-&&-RNA strand annealing activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:EIF4B			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway	EIF4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4B	0.42508874	0.12048193	86	4	FALSE	EIF4B	EIF4B	208.8690476	0	85	0	0.77459167	FALSE	1	EIF4B	337330	0.05152856
792943	taxon:9606	2.29320939	3.49E-04	181104	1902	fatty acid synthase	gene	biological_process-&-1&-GO:0030879-&&-mammary gland development-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006084-&&-acetyl-CoA metabolic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0015939-&&-pantothenate metabolic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042587-&&-glycogen granule-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004320-&&-oleoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0004313-&&-[acyl-carrier-protein] S-acetyltransferase activity-%%-GO:0004315-&&-3-oxoacyl-[acyl-carrier-protein] synthase activity-%%-GO:0008144-&&-drug binding-%%-GO:0102132-&&-3-oxo-pimeloyl-[acp] methyl ester reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0047117-&&-enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity-%%-GO:0004317-&&-3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity-%%-GO:0016295-&&-myristoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0016296-&&-palmitoyl-[acyl-carrier-protein] hydrolase activity-%%-GO:0047451-&&-3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity-%%-GO:0070402-&&-NADPH binding-%%-GO:0031177-&&-phosphopantetheine binding-%%-GO:0004312-&&-fatty acid synthase activity-%%-GO:0004314-&&-[acyl-carrier-protein] S-malonyltransferase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0004319-&&-enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity-%%-GO:0004316-&&-3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	G:9606:FASN	FASN	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa01212-&&-Fatty acid metabolism	FASN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASN	0.43607008	0.12335055	86	4	FALSE	FASN	FASN	234.702381	0	85	0	0.7844651	FALSE	1	FASN	562654	0.05316813
793158	taxon:9606	2.40255239	9.95E-04	180617	1902	G protein subunit alpha i2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0051301-&&-cell division-%%-GO:0001973-&&-adenosine receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0007584-&&-response to nutrient-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0007049-&&-cell cycle-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0051924-&&-regulation of calcium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05012-&&-Parkinson disease-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04916-&&-Melanogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04727-&&-GABAergic synapse-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI2	0.41622401	0.05854993	86	4	FALSE	GNAI2	GNAI2	110.0116279	0	86	0	0.76624127	FALSE	0	GNAI2	1006468	0.02955114
793166	taxon:9606	2.29746337	4.18E-04	180605	1902	G protein subunit beta 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0051020-&&-GTPase binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0032403-&&-protein complex binding	G:9606:GNB2			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB2	0.43526265	0.09411765	86	4	FALSE	GNB2	GNB2	184.6395349	0	86	0	0.78375611	FALSE	0	GNB2	666514	0.04202938
787354	taxon:9606	2.53663148	5.85E-04	179597	1902	melatonin receptor 1B	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007623-&&-circadian rhythm-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0042593-&&-glucose homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008502-&&-melatonin receptor activity	G:9606:MTNR1B	MTNR1B	TRUE	KEGG-&-1&-hsa04713-&&-Circadian entrainment-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	MTNR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTNR1B	0.3942236	0.02879812	85	4	FALSE	MTNR1B	MTNR1B	75.55421687	0	84	0	0.74389475	FALSE	1	MTNR1B	657606	0.02631801
787765	taxon:9606	2.26248621	2.31E-04	178820	1902	peptidylprolyl isomerase A	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0019076-&&-viral release from host cell-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0050900-&&-leukocyte migration-%%-GO:0045069-&&-regulation of viral genome replication-%%-GO:0034389-&&-lipid particle organization-%%-GO:0019058-&&-viral life cycle-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0030260-&&-entry into host cell-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0019061-&&-uncoating of virus-%%-GO:0019068-&&-virion assembly-%%-GO:0006278-&&-RNA-dependent DNA biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046790-&&-virion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PPIA			KEGG-&-1&-hsa04217-&&-Necroptosis	PPIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIA	0.44199164	0.1439906	85	4	FALSE	PPIA	PPIA	234.5421687	0	84	0	0.78958563	FALSE	1	PPIA	500406	0.05090734
787807	taxon:9606	2.31054041	3.97E-04	178763	1902	protein kinase cAMP-dependent type I regulatory subunit alpha	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0001707-&&-mesoderm formation-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007143-&&-female meiotic division-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045214-&&-sarcomere organization-%%-GO:0045835-&&-negative regulation of meiotic nuclear division|cellular_component-&-1&-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0001772-&&-immunological synapse-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0016020-&&-membrane-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0097546-&&-ciliary base-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PRKAR1A			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	PRKAR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAR1A	0.43279918	0.07846018	85	4	FALSE	PRKAR1A	PRKAR1A	170.5662651	0	84	0	0.7815766	FALSE	1	PRKAR1A	559656	0.0395478
788150	taxon:9606	2.52512998	4.58E-04	178156	1902	RAB5A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0036465-&&-synaptic vesicle recycling-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0007596-&&-blood coagulation-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0006897-&&-endocytosis-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0006909-&&-phagocytosis-%%-GO:0051036-&&-regulation of endosome size-%%-GO:2000286-&&-receptor internalization involved in canonical Wnt signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0043679-&&-axon terminus-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0043195-&&-terminal bouton-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0036477-&&-somatodendritic compartment-%%-GO:0098559-&&-cytoplasmic side of early endosome membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0001726-&&-ruffle-%%-GO:0010008-&&-endosome membrane-%%-GO:0030425-&&-dendrite-%%-GO:0045121-&&-membrane raft-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding	G:9606:RAB5A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome-%%-hsa05146-&&-Amoebiasis-%%-hsa05152-&&-Tuberculosis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	RAB5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB5A	0.39601922	0.04525419	85	4	FALSE	RAB5A	RAB5A	73.04819277	0	84	0	0.74581167	FALSE	1	RAB5A	425100	0.02471351
788230	taxon:9606	2.44257129	2.67E-04	178043	1902	serum/glucocorticoid regulated kinase 1	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007616-&&-long-term memory-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0060453-&&-regulation of gastric acid secretion-%%-GO:0006950-&&-response to stress-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032411-&&-positive regulation of transporter activity-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0070294-&&-renal sodium ion absorption|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005524-&&-ATP binding	G:9606:SGK1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04150-&&-mTOR signaling pathway	SGK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGK1	0.40940463	0.06406112	85	4	FALSE	SGK1	SGK1	119.1084337	0	84	0	0.75957145	FALSE	1	SGK1	356412	0.03415614
788616	taxon:9606	2.33291319	2.71E-04	177303	1902	peroxiredoxin 2	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0016209-&&-antioxidant activity	G:9606:PRDX2	PRDX2	TRUE		PRDX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX2	0.42864861	0.1354687	85	4	FALSE	PRDX2	PRDX2	166.4096386	0	84	0	0.7778478	FALSE	1	PRDX2	465946	0.03998981
789095	taxon:9606	2.36915078	2.51E-04	176203	1902	far upstream element binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:FUBP1				FUBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUBP1	0.42209217	0.11596639	85	4	FALSE	FUBP1	FUBP1	181.2470588	0	85	0	0.7718082	FALSE	0	FUBP1	474792	0.04602489
789258	taxon:9606	2.37119899	1.91E-04	175884	1902	eukaryotic translation initiation factor 3 subunit I	gene	biological_process-&-1&-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3I			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3I	0.42172757	0.1464986	85	4	FALSE	EIF3I	EIF3I	184.3647059	0	85	0	0.77146683	FALSE	0	EIF3I	392294	0.04698685
789555	taxon:9606	2.34866866	4.49E-04	175195	1902	kelch like ECH associated protein 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045604-&&-regulation of epidermal cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005884-&&-actin filament-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:KEAP1	KEAP1	TRUE	KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma	KEAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KEAP1	0.42577313	0.06553041	85	4	FALSE	KEAP1	KEAP1	132	0	84	0	0.77522189	FALSE	1	KEAP1	541204	0.03247258
789713	taxon:9606	2.33370096	1.71E-04	174846	1902	acidic nuclear phosphoprotein 32 family member B	gene	biological_process-&-1&-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0048839-&&-inner ear development-%%-GO:0001944-&&-vasculature development-%%-GO:0060021-&&-palate development-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0021591-&&-ventricular system development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0070063-&&-RNA polymerase binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding	G:9606:ANP32B				ANP32B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANP32B	0.42850392	0.15238095	85	4	FALSE	ANP32B	ANP32B	223.7529412	0	85	0	0.77771651	FALSE	0	ANP32B	466934	0.0537367
789759	taxon:9606	2.38191271	1.59E-04	174759	1902	RAD50 double strand break repair protein	gene	biological_process-&-1&-GO:0000019-&&-regulation of mitotic recombination-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0046939-&&-nucleotide phosphorylation-%%-GO:0000723-&&-telomere maintenance-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000732-&&-strand displacement-%%-GO:0006281-&&-DNA repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0016032-&&-viral process-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006310-&&-DNA recombination-%%-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0031860-&&-telomeric 3' overhang formation|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030870-&&-Mre11 complex-%%-GO:0016020-&&-membrane-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0043047-&&-single-stranded telomeric DNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0000014-&&-single-stranded DNA endodeoxyribonuclease activity-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004017-&&-adenylate kinase activity	G:9606:RAD50			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining-%%-hsa04218-&&-Cellular senescence-%%-hsa03440-&&-Homologous recombination	RAD50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD50	0.41983067	0.16302521	85	4	FALSE	RAD50	RAD50	228.4117647	0	85	0	0.76968121	FALSE	0	RAD50	390304	0.05908531
790022	taxon:9606	2.57507484	4.22E-04	174073	1902	RNA binding protein with multiple splicing	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006396-&&-RNA processing-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005685-&&-U1 snRNP-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0008143-&&-poly(A) binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0035614-&&-snRNA stem-loop binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBPMS				RBPMS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBPMS	0.38833823	0.03349985	85	4	FALSE	RBPMS	RBPMS	64.18072289	0	84	0	0.73748753	FALSE	1	RBPMS	413422	0.02417382
790564	taxon:9606	2.39924374	1.60E-04	172125	1902	ring finger protein 11	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0055037-&&-recycling endosome-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF11				RNF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF11	0.416798	0.12812225	85	4	FALSE	RNF11	RNF11	133.7710843	0	84	0	0.76679271	FALSE	1	RNF11	295148	0.03574533
790789	taxon:9606	2.5240271	2.96E-04	171192	1902	DNA methyltransferase 3 like	gene	biological_process-&-1&-GO:1905643-&&-positive regulation of DNA methylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006306-&&-DNA methylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0007141-&&-male meiosis I-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0032776-&&-DNA methylation on cytosine-%%-GO:1905642-&&-negative regulation of DNA methylation-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008047-&&-enzyme activator activity	G:9606:DNMT3L				DNMT3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT3L	0.39619226	0.09131653	85	4	FALSE	DNMT3L	DNMT3L	127.6705882	0	85	0	0.74599548	FALSE	0	DNMT3L	468418	0.04249084
791895	taxon:9606	2.30534111	3.23E-04	182913	1902	adaptor related protein complex 2 beta 1 subunit	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0035904-&&-aorta development-%%-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0099590-&&-neurotransmitter receptor internalization-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0003281-&&-ventricular septum development-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0030276-&&-clathrin binding-%%-GO:0005048-&&-signal sequence binding-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0032403-&&-protein complex binding	G:9606:AP2B1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2B1	0.43377529	0.1535014	85	4	FALSE	AP2B1	AP2B1	192.3294118	0	85	0	0.78244315	FALSE	0	AP2B1	527220	0.04432512
792304	taxon:9606	2.32960454	4.35E-04	182258	1902	CCAAT/enhancer binding protein beta	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0072574-&&-hepatocyte proliferation-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006954-&&-inflammatory response-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006955-&&-immune response-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006953-&&-acute-phase response-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0045408-&&-regulation of interleukin-6 biosynthetic process-%%-GO:0097421-&&-liver regeneration-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0007613-&&-memory-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036488-&&-CHOP-C/EBP complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0044389-&&-ubiquitin-like protein ligase binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:CEBPB			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05152-&&-Tuberculosis	CEBPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPB	0.42925741	0.19541581	85	4	FALSE	CEBPB	CEBPB	161.5301205	0	84	0	0.77839924	FALSE	1	CEBPB	563468	0.0384601
792535	taxon:9606	2.34315425	1.74E-04	181841	1902	capping actin protein of muscle Z-line alpha subunit 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0071203-&&-WASH complex-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CAPZA1			KEGG-&-1&-hsa04144-&&-Endocytosis	CAPZA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPZA1	0.42677515	0.14257703	85	4	FALSE	CAPZA1	CAPZA1	220.3058824	0	85	0	0.77614096	FALSE	0	CAPZA1	413568	0.05376387
792857	taxon:9606	2.38002206	9.34E-05	181260	1902	ERG, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016477-&&-cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003199-&&-endocardial cushion to mesenchymal transition involved in heart valve formation-%%-GO:0007165-&&-signal transduction-%%-GO:2000504-&&-positive regulation of blood vessel remodeling-%%-GO:0007275-&&-multicellular organism development-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ERG			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer	ERG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERG	0.42016417	0.13664414	85	4	FALSE	ERG	ERG	176.9879518	0	84	0	0.76999632	FALSE	1	ERG	220260	0.04567677
792874	taxon:9606	2.38112494	3.65E-04	181241	1902	ETS proto-oncogene 1, transcription factor	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061614-&&-pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0044849-&&-estrous cycle-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0030578-&&-PML body organization-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0021983-&&-pituitary gland development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0032355-&&-response to estradiol-%%-GO:1904996-&&-positive regulation of leukocyte adhesion to vascular endothelial cell-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0006955-&&-immune response-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0021854-&&-hypothalamus development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048870-&&-cell motility|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding	G:9606:ETS1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa05211-&&-Renal cell carcinoma	ETS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETS1	0.41996956	0.10578901	85	4	FALSE	ETS1	ETS1	137.1686747	0	84	0	0.76981251	FALSE	1	ETS1	457712	0.03545878
787922	taxon:9606	2.44194107	1.23E-04	178604	1902	prothymosin, alpha	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PTMA				PTMA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTMA	0.40951029	0.12994836	84	4	FALSE	PTMA	PTMA	169.2738095	0	84	0	0.75967649	FALSE	0	PTMA	289124	0.04851643
788748	taxon:9606	2.32456279	4.86E-04	177044	1902	titin	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0051592-&&-response to calcium ion-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0030241-&&-skeletal muscle myosin thick filament assembly-%%-GO:0048769-&&-sarcomerogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0035995-&&-detection of muscle stretch-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0048739-&&-cardiac muscle fiber development-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc-%%-GO:0005859-&&-muscle myosin complex-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0031430-&&-M band-%%-GO:0031674-&&-I band-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0051371-&&-muscle alpha-actinin binding-%%-GO:0042805-&&-actinin binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0031433-&&-telethonin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0043621-&&-protein self-association-%%-GO:0019899-&&-enzyme binding	G:9606:TTN			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)	TTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTN	0.43018842	0.09153869	84	4	FALSE	TTN	TTN	179.902439	0	83	0	0.77923954	FALSE	1	TTN	622958	0.04267714
788941	taxon:9606	2.4495037	1.87E-04	160169	1902	TMEM189-UBE2V1 readthrough	gene		G:9606:TMEM189-UBE2V1				TMEM189-UBE2V1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM189-UBE2V1	0.40824596	0.12887684	84	4	FALSE	TMEM189-UBE2V1	TMEM189-UBE2V1	129.5243902	0	83	0	0.75841605	FALSE	1	TMEM189-UBE2V1	354892	0.03759779
789422	taxon:9606	2.32566567	1.86E-04	175516	1902	BCL2 associated transcription factor 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:BCLAF1				BCLAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCLAF1	0.42998442	0.15863454	84	4	FALSE	BCLAF1	BCLAF1	237.7857143	0	84	0	0.77905572	FALSE	0	BCLAF1	478586	0.05635786
789460	taxon:9606	2.4178352	2.10E-04	175417	1902	H2A histone family member Y	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0007549-&&-dosage compensation-%%-GO:0006342-&&-chromatin silencing-%%-GO:1901837-&&-negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0001558-&&-regulation of cell growth-%%-GO:1902882-&&-regulation of response to oxidative stress-%%-GO:1902750-&&-negative regulation of cell cycle G2/M phase transition-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0061187-&&-regulation of chromatin silencing at rDNA-%%-GO:0033128-&&-negative regulation of histone phosphorylation-%%-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:0034184-&&-positive regulation of maintenance of mitotic sister chromatid cohesion-%%-GO:1904815-&&-negative regulation of protein localization to chromosome, telomeric region-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0001740-&&-Barr body-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000786-&&-nucleosome-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0001739-&&-sex chromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0000182-&&-rDNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0010385-&&-double-stranded methylated DNA binding	G:9606:H2AFY			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	H2AFY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H2AFY	0.41359312	0.35513483	84	4	FALSE	H2AFY	H2AFY	227.9642857	0	84	0	0.76369413	FALSE	0	H2AFY	421312	0.06258989
789729	taxon:9606	2.32298724	2.90E-04	174814	1902	programmed cell death 6	gene	biological_process-&-1&-GO:0051592-&&-response to calcium ion-%%-GO:0036324-&&-vascular endothelial growth factor receptor-2 signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006508-&&-proteolysis-%%-GO:0001525-&&-angiogenesis-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0060090-&&-binding, bridging-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0043495-&&-protein anchor-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PDCD6				PDCD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD6	0.4304802	0.11833785	84	4	FALSE	PDCD6	PDCD6	181.0121951	0	83	0	0.77950213	FALSE	1	PDCD6	470244	0.04275639
789790	taxon:9606	2.39057823	2.40E-04	174672	1902	flotillin 1	gene	biological_process-&-1&-GO:0070528-&&-protein kinase C signaling-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0044854-&&-plasma membrane raft assembly-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0034143-&&-regulation of toll-like receptor 4 signaling pathway-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0007409-&&-axonogenesis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:1903044-&&-protein localization to membrane raft-%%-GO:0032226-&&-positive regulation of synaptic transmission, dopaminergic-%%-GO:0060355-&&-positive regulation of cell adhesion molecule production-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0033227-&&-dsRNA transport-%%-GO:0001765-&&-membrane raft assembly-%%-GO:1901890-&&-positive regulation of cell junction assembly-%%-GO:0022617-&&-extracellular matrix disassembly|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016600-&&-flotillin complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0034451-&&-centriolar satellite-%%-GO:0042470-&&-melanosome-%%-GO:0030027-&&-lamellipodium-%%-GO:0005769-&&-early endosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane-%%-GO:0005901-&&-caveola-%%-GO:0042383-&&-sarcolemma-%%-GO:0005911-&&-cell-cell junction-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:FLOT1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	FLOT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLOT1	0.41830884	0.10298336	84	4	FALSE	FLOT1	FLOT1	173.25	0	84	0	0.76823696	FALSE	0	FLOT1	493364	0.04555873
789841	taxon:9606	2.41436899	2.88E-04	174533	1902	mortality factor 4 like 1	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0016575-&&-histone deacetylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006342-&&-chromatin silencing-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:MORF4L1				MORF4L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MORF4L1	0.4141869	0.10990665	84	4	FALSE	MORF4L1	MORF4L1	131.4756098	0	83	0	0.76427183	FALSE	1	MORF4L1	421134	0.0358925
790459	taxon:9606	2.35890972	3.51E-04	172793	1902	UBX domain protein 7	gene	cellular_component-&-1&-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:UBXN7				UBXN7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN7	0.42392466	0.14285714	84	4	FALSE	UBXN7	UBXN7	152.1190476	0	84	0	0.77351505	FALSE	0	UBXN7	531480	0.03797039
791318	taxon:9606	2.78257444	2.11E-04	169202	1902	coenzyme Q9	gene	biological_process-&-1&-GO:0006744-&&-ubiquinone biosynthetic process-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008289-&&-lipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:COQ9				COQ9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COQ9	0.35937942	0.05149051	84	4	FALSE	COQ9	COQ9	39.62195122	0	83	0	0.70290426	FALSE	1	COQ9	215984	0.02794499
791837	taxon:9606	2.4394202	0.00113543	182993	1902	alpha-2-macroglobulin	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0001869-&&-negative regulation of complement activation, lectin pathway-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0022617-&&-extracellular matrix disassembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0019959-&&-interleukin-8 binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0043120-&&-tumor necrosis factor binding	G:9606:A2M			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	A2M	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-A2M	0.40993348	0.05179163	84	4	FALSE	A2M	A2M	90.42682927	0	83	0	0.76009663	FALSE	1	A2M	1193248	0.02589495
791999	taxon:9606	2.44934615	3.34E-04	182749	1902	B-cell CLL/lymphoma 6	gene	biological_process-&-1&-GO:0050776-&&-regulation of immune response-%%-GO:0048821-&&-erythrocyte development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048294-&&-negative regulation of isotype switching to IgE isotypes-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0042092-&&-type 2 immune response-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043380-&&-regulation of memory T cell differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0002467-&&-germinal center formation-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032764-&&-negative regulation of mast cell cytokine production-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0045629-&&-negative regulation of T-helper 2 cell differentiation-%%-GO:0030183-&&-B cell differentiation|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001161-&&-intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:BCL6			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer	BCL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL6	0.40827222	0.09996989	84	4	FALSE	BCL6	BCL6	127.902439	0	83	0	0.75844231	FALSE	1	BCL6	443244	0.03704489
793125	taxon:9606	2.53017173	2.75E-04	180686	1902	growth hormone 1	gene	biological_process-&-1&-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0015758-&&-glucose transport-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0010535-&&-positive regulation of activation of JAK2 kinase activity-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0070977-&&-bone maturation-%%-GO:0032355-&&-response to estradiol-%%-GO:0060396-&&-growth hormone receptor signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031904-&&-endosome lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005131-&&-growth hormone receptor binding-%%-GO:0005148-&&-prolactin receptor binding-%%-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0046872-&&-metal ion binding	G:9606:GH1	GH1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	GH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GH1	0.39523009	0.05149051	84	4	FALSE	GH1	GH1	106.8658537	0	83	0	0.74497138	FALSE	1	GH1	429480	0.0363693
793349	taxon:9606	2.30250512	2.02E-04	180258	1902	high mobility group AT-hook 1	gene	biological_process-&-1&-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0031936-&&-negative regulation of chromatin silencing-%%-GO:0006284-&&-base-excision repair-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090402-&&-oncogene-induced cell senescence-%%-GO:0009615-&&-response to virus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0035986-&&-senescence-associated heterochromatin focus assembly-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051169-&&-nuclear transport|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0035985-&&-senescence-associated heterochromatin focus|molecular_function-&-1&-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0003677-&&-DNA binding	G:9606:HMGA1				HMGA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGA1	0.43430957	0.1394148	84	4	FALSE	HMGA1	HMGA1	188.8928571	0	84	0	0.78291581	FALSE	0	HMGA1	405502	0.04335563
787767	taxon:9606	2.34189381	2.61E-04	178819	1902	peptidylprolyl isomerase B	gene	biological_process-&-1&-GO:0060348-&&-bone development-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050821-&&-protein stabilization-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:1901873-&&-regulation of post-translational protein modification-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0044829-&&-positive regulation by host of viral genome replication|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016020-&&-membrane-%%-GO:0032991-&&-macromolecular complex-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:PPIB				PPIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIB	0.42700484	0.1072583	83	4	FALSE	PPIB	PPIB	191.2048193	0	83	0	0.77635103	FALSE	0	PPIB	517042	0.04651013
788214	taxon:9606	2.43752954	1.89E-04	178064	1902	RELB proto-oncogene, NF-kB subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0071470-&&-cellular response to osmotic stress-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0045063-&&-T-helper 1 cell differentiation-%%-GO:0034097-&&-response to cytokine-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0033256-&&-I-kappaB/NF-kappaB complex-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding	G:9606:RELB	RELB	TRUE	KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway	RELB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RELB	0.41025144	0.12407407	83	4	FALSE	RELB	RELB	146.9506173	0	82	0	0.76041174	FALSE	1	RELB	307734	0.04176405
788565	taxon:9606	2.48479597	1.30E-04	177421	1902	TATA-box binding protein associated factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010767-&&-regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage-%%-GO:1902806-&&-regulation of cell cycle G1/S phase transition-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:1905524-&&-negative regulation of protein autoubiquitination-%%-GO:2000825-&&-positive regulation of androgen receptor activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0036369-&&-transcription factor catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0030901-&&-midbrain development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0016573-&&-histone acetylation-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0060260-&&-regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001129-&&-RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly-%%-GO:0005524-&&-ATP binding-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:1905502-&&-acetyl-CoA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0061628-&&-H3K27me3 modified histone binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:TAF1			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1	0.40244753	0.20185185	83	4	FALSE	TAF1	TAF1	180.1111111	0	82	0	0.75253401	FALSE	1	TAF1	301218	0.05571981
788725	taxon:9606	2.47518513	2.00E-04	177118	1902	TNF receptor associated factor 3	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030162-&&-regulation of proteolysis-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0008063-&&-Toll signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0007165-&&-signal transduction-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032648-&&-regulation of interferon-beta production-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0050688-&&-regulation of defense response to virus-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031996-&&-thioesterase binding	G:9606:TRAF3			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway	TRAF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF3	0.40401018	0.09660494	83	4	FALSE	TRAF3	TRAF3	105.5432099	0	82	0	0.75413581	FALSE	1	TRAF3	295054	0.03206875
788819	taxon:9606	2.46573184	2.22E-04	176814	1902	ubiquitin conjugating enzyme E2 E1	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0032020-&&-ISG15-protein conjugation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042296-&&-ISG15 transferase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2E1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E1	0.40555911	0.04135802	83	4	FALSE	UBE2E1	UBE2E1	109.0617284	0	82	0	0.75571136	FALSE	1	UBE2E1	394130	0.03267734
789443	taxon:9606	2.41137545	2.64E-04	175454	1902	FMR1 autosomal homolog 2	gene	biological_process-&-1&-GO:0017148-&&-negative regulation of translation|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:FXR2			KEGG-&-1&-hsa03013-&&-RNA transport	FXR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FXR2	0.41470108	0.06820988	83	4	FALSE	FXR2	FXR2	135.617284	0	82	0	0.76477076	FALSE	1	FXR2	418324	0.03682904
789705	taxon:9606	2.5689302	1.87E-04	174853	1902	Sjogren syndrome/scleroderma autoantigen 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SSSCA1				SSSCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSSCA1	0.3892671	0.07407407	83	4	FALSE	SSSCA1	SSSCA1	82.01234568	0	82	0	0.73851163	FALSE	1	SSSCA1	241156	0.03030469
790091	taxon:9606	2.38411848	2.17E-04	173893	1902	glucosidase II alpha subunit	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0017177-&&-glucosidase II complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0033919-&&-glucan 1,3-alpha-glucosidase activity	G:9606:GANAB			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	GANAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GANAB	0.41944224	0.11166618	83	4	FALSE	GANAB	GANAB	173.6987952	0	83	0	0.76931359	FALSE	0	GANAB	434348	0.0450518
792067	taxon:9606	2.31117063	2.57E-04	166280	1902	translocase of inner mitochondrial membrane 50	gene	biological_process-&-1&-GO:0007006-&&-mitochondrial membrane organization-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0030150-&&-protein import into mitochondrial matrix-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005744-&&-mitochondrial inner membrane presequence translocase complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005134-&&-interleukin-2 receptor binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:TIMM50				TIMM50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMM50	0.43268116	0.09756098	83	4	FALSE	TIMM50	TIMM50	202.5421687	0	83	0	0.78147156	FALSE	0	TIMM50	528158	0.0469009
792173	taxon:9606	2.40018907	2.38E-04	182479	1902	A-Raf proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:ARAF			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa04730-&&-Long-term depression-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04720-&&-Long-term potentiation-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	ARAF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARAF	0.41663385	0.08703704	83	4	FALSE	ARAF	ARAF	135.4691358	0	82	0	0.76663516	FALSE	1	ARAF	361262	0.03603204
792248	taxon:9606	2.39924374	2.12E-04	182355	1902	ATPase H+ transporting V1 subunit B2	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0015992-&&-proton transport-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0001726-&&-ruffle-%%-GO:0012505-&&-endomembrane system-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0015078-&&-hydrogen ion transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V1B2			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05165-&&-Human papillomavirus infection	ATP6V1B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1B2	0.416798	0.1072583	83	4	FALSE	ATP6V1B2	ATP6V1B2	133.4096386	0	83	0	0.76679271	FALSE	0	ATP6V1B2	341486	0.03544358
792291	taxon:9606	2.31747282	1.67E-04	182277	1902	cyclin dependent kinase inhibitor 1B	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048839-&&-inner ear development-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:1902746-&&-regulation of lens fiber cell differentiation-%%-GO:0001890-&&-placenta development-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0009749-&&-response to glucose-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0043200-&&-response to amino acid-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0042493-&&-response to drug-%%-GO:0048102-&&-autophagic cell death-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0006813-&&-potassium ion transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0032355-&&-response to estradiol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0051271-&&-negative regulation of cellular component movement|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005072-&&-transforming growth factor beta receptor, cytoplasmic mediator activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0032403-&&-protein complex binding	G:9606:CDKN1B	CDKN1B	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05226-&&-Gastric cancer	CDKN1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN1B	0.43150452	0.15221863	83	4	FALSE	CDKN1B	CDKN1B	186.2650602	0	83	0	0.7804212	FALSE	0	CDKN1B	358044	0.04364224
792539	taxon:9606	2.31479439	1.98E-04	181838	1902	capping actin protein of muscle Z-line beta subunit	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0051490-&&-negative regulation of filopodium assembly-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0010591-&&-regulation of lamellipodium assembly-%%-GO:0007596-&&-blood coagulation-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0071203-&&-WASH complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030017-&&-sarcomere|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding	G:9606:CAPZB			KEGG-&-1&-hsa04144-&&-Endocytosis	CAPZB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPZB	0.43200381	0.136938	83	4	FALSE	CAPZB	CAPZB	223.4939759	0	83	0	0.7808676	FALSE	0	CAPZB	442942	0.0522154
792547	taxon:9606	2.45360013	3.12E-04	181830	1902	caspase 7	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006508-&&-proteolysis-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity	G:9606:CASP7			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05133-&&-Pertussis-%%-hsa05134-&&-Legionellosis	CASP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP7	0.40756437	0.09351852	83	4	FALSE	CASP7	CASP7	105.7530864	0	82	0	0.75773331	FALSE	1	CASP7	397568	0.03090388
793227	taxon:9606	2.27162439	3.49E-04	180496	1902	DnaJ heat shock protein family (Hsp40) member B1	gene	biological_process-&-1&-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0097201-&&-negative regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0051087-&&-chaperone binding	G:9606:DNAJB1			KEGG-&-1&-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB1	0.44021362	0.12224508	83	4	FALSE	DNAJB1	DNAJB1	184.5903615	0	83	0	0.7880626	FALSE	0	DNAJB1	606132	0.04060599
787125	taxon:9606	2.49204349	3.02E-04	180017	1902	forkhead box K2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:FOXK2				FOXK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXK2	0.40127711	0.08822644	82	4	FALSE	FOXK2	FOXK2	108.0731707	0	82	0	0.75132609	FALSE	0	FOXK2	362104	0.03355079
787228	taxon:9606	2.32598078	2.89E-04	179828	1902	inositol polyphosphate phosphatase like 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0097178-&&-ruffle assembly-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0032868-&&-response to insulin-%%-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007015-&&-actin filament organization-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0009791-&&-post-embryonic development-%%-GO:0002376-&&-immune system process-%%-GO:0007155-&&-cell adhesion-%%-GO:0001958-&&-endochondral ossification-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030175-&&-filopodium-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0052659-&&-inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity-%%-GO:0034485-&&-phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	G:9606:INPPL1			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa00562-&&-Inositol phosphate metabolism	INPPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INPPL1	0.42992617	0.155676	82	4	FALSE	INPPL1	INPPL1	177.1829268	0	82	0	0.7790032	FALSE	0	INPPL1	437220	0.04209041
788092	taxon:9606	2.3398456	1.98E-04	178253	1902	phosphoglycerate kinase 1	gene	biological_process-&-1&-GO:0016310-&&-phosphorylation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004618-&&-phosphoglycerate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PGK1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	PGK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGK1	0.42737863	0.18247516	82	4	FALSE	PGK1	PGK1	199.6097561	0	82	0	0.7766924	FALSE	0	PGK1	383036	0.04831996
788534	taxon:9606	2.44824326	1.77E-04	161106	1902	ubiquitin conjugating enzyme E2 E4 pseudogene	gene		G:9606:UBE2E4P				UBE2E4P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E4P	0.40845614	0.08227848	82	4	FALSE	UBE2E4P	UBE2E4P	126.8375	0	81	0	0.75862612	FALSE	1	UBE2E4P	346078	0.03671129
788744	taxon:9606	2.51000473	2.62E-04	177051	1902	tetratricopeptide repeat domain 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:TTC1				TTC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC1	0.39840562	0.07648299	82	4	FALSE	TTC1	TTC1	116.6219512	0	82	0	0.74833255	FALSE	0	TTC1	411950	0.03821325
788813	taxon:9606	2.412951	1.72E-04	176823	1902	ubiquitin A-52 residue ribosomal protein fusion product 1	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0017085-&&-response to insecticide-%%-GO:0019058-&&-viral life cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0019068-&&-virion assembly-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006413-&&-translational initiation-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007254-&&-JNK cascade-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016197-&&-endosomal transport-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019083-&&-viral transcription-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0016236-&&-macroautophagy-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006364-&&-rRNA processing-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0060544-&&-regulation of necroptotic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:UBA52			KEGG-&-1&-hsa03010-&&-Ribosome	UBA52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA52	0.4144303	0.18734177	82	4	FALSE	UBA52	UBA52	167.775	0	81	0	0.76450817	FALSE	1	UBA52	312274	0.0457515
788864	taxon:9606	2.4658894	1.84E-04	176739	1902	voltage dependent anion channel 3	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0006820-&&-anion transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:1903959-&&-regulation of anion transmembrane transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0046930-&&-pore complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008308-&&-voltage-gated anion channel activity-%%-GO:0015288-&&-porin activity	G:9606:VDAC3			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04216-&&-Ferroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	VDAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VDAC3	0.40553319	0.15718157	82	4	FALSE	VDAC3	VDAC3	127.9390244	0	82	0	0.7556851	FALSE	0	VDAC3	313242	0.03827072
789387	taxon:9606	2.40822436	2.47E-04	175599	1902	ribosomal protein S6 kinase A5	gene	biological_process-&-1&-GO:0043988-&&-histone H3-S28 phosphorylation-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0043987-&&-histone H3-S10 phosphorylation-%%-GO:0043990-&&-histone H2A-S1 phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:RPS6KA5			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	RPS6KA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA5	0.4152437	0.17946402	82	4	FALSE	RPS6KA5	RPS6KA5	191.7560976	0	82	0	0.76529594	FALSE	0	RPS6KA5	479464	0.05184494
789611	taxon:9606	2.33133764	2.26E-04	175056	1902	nucleoporin 153	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0075732-&&-viral penetration into host nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0046832-&&-negative regulation of RNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005730-&&-nucleolus-%%-GO:0034399-&&-nuclear periphery-%%-GO:0044613-&&-nuclear pore central transport channel|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0043495-&&-protein anchor-%%-GO:0042802-&&-identical protein binding	G:9606:NUP153			KEGG-&-1&-hsa03013-&&-RNA transport	NUP153	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP153	0.4289383	0.1414557	82	4	FALSE	NUP153	NUP153	168.2625	0	81	0	0.77811039	FALSE	1	NUP153	365604	0.04006609
789685	taxon:9606	2.44824326	1.77E-04	174899	1902	ubiquitin conjugating enzyme E2 E3	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2E3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E3	0.40845614	0.08227848	82	4	FALSE	UBE2E3	UBE2E3	126.8375	0	81	0	0.75862612	FALSE	1	UBE2E3	346078	0.03671129
790447	taxon:9606	2.39089334	6.41E-05	172838	1902	pre-mRNA processing factor 6	gene	biological_process-&-1&-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0006403-&&-RNA localization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0050681-&&-androgen receptor binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PRPF6			KEGG-&-1&-hsa03040-&&-Spliceosome	PRPF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF6	0.41825371	0.26898734	82	4	FALSE	PRPF6	PRPF6	208.825	0	81	0	0.76818444	FALSE	1	PRPF6	181112	0.05453774
790691	taxon:9606	2.40853947	1.06E-04	171466	1902	ubiquitin like with PHD and ring finger domains 1	gene	biological_process-&-1&-GO:0010390-&&-histone monoubiquitination-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0090308-&&-regulation of methylation-dependent chromatin silencing-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000791-&&-euchromatin|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0042393-&&-histone binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031493-&&-nucleosomal histone binding-%%-GO:0044729-&&-hemi-methylated DNA-binding	G:9606:UHRF1				UHRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UHRF1	0.41518938	0.26677215	82	4	FALSE	UHRF1	UHRF1	236.4125	0	81	0	0.76524342	FALSE	1	UHRF1	269562	0.06377496
791760	taxon:9606	2.50527808	1.11E-04	166991	1902	SprT-like N-terminal domain	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0019985-&&-translesion synthesis-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0031398-&&-positive regulation of protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0043130-&&-ubiquitin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:SPRTN	SPRTN	TRUE		SPRTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRTN	0.39915729	0.0788919	82	4	FALSE	SPRTN	SPRTN	131.5731707	0	82	0	0.74912032	FALSE	0	SPRTN	228646	0.04251141
791973	taxon:9606	2.38443359	1.64E-04	182780	1902	autoimmune regulator	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032602-&&-chemokine production-%%-GO:0097536-&&-thymus epithelium morphogenesis-%%-GO:0006417-&&-regulation of translation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006955-&&-immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000410-&&-regulation of thymocyte migration-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0002509-&&-central tolerance induction to self antigen-%%-GO:0006959-&&-humoral immune response-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0002458-&&-peripheral T cell tolerance induction|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:AIRE			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05340-&&-Primary immunodeficiency	AIRE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIRE	0.41938681	0.17120253	82	4	FALSE	AIRE	AIRE	211.3875	0	81	0	0.76926107	FALSE	1	AIRE	339774	0.05480744
792189	taxon:9606	2.35528596	2.50E-04	182457	1902	Rho GDP dissociation inhibitor alpha	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005094-&&-Rho GDP-dissociation inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARHGDIA			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption	ARHGDIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGDIA	0.42457689	0.10696203	82	4	FALSE	ARHGDIA	ARHGDIA	165.325	0	81	0	0.77411901	FALSE	1	ARHGDIA	432768	0.04085517
792441	taxon:9606	2.2969907	3.71E-04	182015	1902	catenin alpha 1	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0034613-&&-cellular protein localization-%%-GO:0031103-&&-axon regeneration-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0043627-&&-response to estrogen-%%-GO:2001045-&&-negative regulation of integrin-mediated signaling pathway-%%-GO:0071681-&&-cellular response to indole-3-methanol-%%-GO:0007406-&&-negative regulation of neuroblast proliferation-%%-GO:0007568-&&-aging-%%-GO:0008584-&&-male gonad development-%%-GO:0016264-&&-gap junction assembly-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0034332-&&-adherens junction organization-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007015-&&-actin filament organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0043297-&&-apical junction assembly-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005915-&&-zonula adherens-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0016342-&&-catenin complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0014704-&&-intercalated disc-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016600-&&-flotillin complex|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0003723-&&-RNA binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0045295-&&-gamma-catenin binding	G:9606:CTNNA1			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05226-&&-Gastric cancer	CTNNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNA1	0.43535222	0.10506329	82	4	FALSE	CTNNA1	CTNNA1	180.225	0	81	0	0.78383488	FALSE	1	CTNNA1	549522	0.04100478
792722	taxon:9606	2.42114385	7.72E-05	181496	1902	dyskerin pseudouridine synthase 1	gene	biological_process-&-1&-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0090669-&&-telomerase RNA stabilization-%%-GO:0006396-&&-RNA processing-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0031120-&&-snRNA pseudouridine synthesis-%%-GO:1990481-&&-mRNA pseudouridine synthesis-%%-GO:0006364-&&-rRNA processing-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0031118-&&-rRNA pseudouridine synthesis-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0000495-&&-box H/ACA snoRNA 3'-end processing-%%-GO:1904851-&&-positive regulation of establishment of protein localization to telomere|cellular_component-&-1&-GO:0090661-&&-box H/ACA telomerase RNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0031429-&&-box H/ACA snoRNP complex-%%-GO:0072589-&&-box H/ACA scaRNP complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003720-&&-telomerase activity-%%-GO:0009982-&&-pseudouridine synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0034513-&&-box H/ACA snoRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding	G:9606:DKC1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	DKC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DKC1	0.41302792	0.20316456	82	4	FALSE	DKC1	DKC1	180.0625	0	81	0	0.76314269	FALSE	1	DKC1	187496	0.04964158
787150	taxon:9606	2.33039231	2.15E-04	179977	1902	lamin B1	gene	cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0005638-&&-lamin filament-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0043274-&&-phospholipase binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:LMNB1			KEGG-&-1&-hsa04210-&&-Apoptosis	LMNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMNB1	0.4291123	0.11716975	81	4	FALSE	LMNB1	LMNB1	207.6202532	0	80	0	0.77826795	FALSE	1	LMNB1	423406	0.04961033
787187	taxon:9606	2.50795651	3.65E-04	179904	1902	SMAD family member 9	gene	biological_process-&-1&-GO:0030902-&&-hindbrain development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0060348-&&-bone development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0001657-&&-ureteric bud development-%%-GO:0051216-&&-cartilage development-%%-GO:0030901-&&-midbrain development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0071141-&&-SMAD protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	G:9606:SMAD9			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD9	0.398731	0.03732554	81	4	FALSE	SMAD9	SMAD9	91.34177215	0	80	0	0.74867391	FALSE	1	SMAD9	389564	0.02979941
787899	taxon:9606	2.45281235	1.10E-04	178640	1902	proteasome 26S subunit, non-ATPase 8	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043248-&&-proteasome assembly-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0022624-&&-proteasome accessory complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex	G:9606:PSMD8			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	PSMD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD8	0.40769527	0.36481481	81	4	FALSE	PSMD8	PSMD8	146.691358	0	81	0	0.75786461	FALSE	0	PSMD8	205314	0.04277603
788076	taxon:9606	2.46793761	2.90E-05	178279	1902	ribosomal protein L34	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL34			KEGG-&-1&-hsa03010-&&-Ribosome	RPL34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL34	0.40519663	0.62006173	81	4	FALSE	RPL34	RPL34	191.4197531	0	81	0	0.75534373	FALSE	0	RPL34	95928	0.05735913
788556	taxon:9606	2.43721443	2.86E-04	177445	1902	supervillin	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007519-&&-skeletal muscle tissue development|cellular_component-&-1&-GO:0071437-&&-invadopodium-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0036449-&&-microtubule minus-end-%%-GO:0030496-&&-midbody-%%-GO:0043034-&&-costamere-%%-GO:0002102-&&-podosome-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:SVIL				SVIL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SVIL	0.41030448	0.11080247	81	4	FALSE	SVIL	SVIL	128.8518519	0	81	0	0.76046426	FALSE	0	SVIL	395980	0.03665749
788712	taxon:9606	2.37340476	2.78E-04	177136	1902	tropomyosin 1 (alpha)	gene	biological_process-&-1&-GO:0031529-&&-ruffle organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0003065-&&-positive regulation of heart rate by epinephrine-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006937-&&-regulation of muscle contraction-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:1904753-&&-negative regulation of vascular associated smooth muscle cell migration-%%-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045214-&&-sarcomere organization-%%-GO:0042060-&&-wound healing-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0060048-&&-cardiac muscle contraction|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0032059-&&-bleb-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032587-&&-ruffle membrane-%%-GO:0030017-&&-sarcomere-%%-GO:0005884-&&-actin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:TPM1	TPM1	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM1	0.42133563	0.11132749	81	4	FALSE	TPM1	TPM1	140.886076	0	80	0	0.77109921	FALSE	1	TPM1	410546	0.03590961
789069	taxon:9606	2.54986608	3.83E-04	159866	1902	keratin associated protein 10-7	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KRTAP10-7				KRTAP10-7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-7	0.39217746	0.09250243	81	4	FALSE	KRTAP10-7	KRTAP10-7	71.58227848	0	80	0	0.74168899	FALSE	1	KRTAP10-7	405740	0.02540639
789341	taxon:9606	2.37734363	3.75E-04	175706	1902	large tumor suppressor kinase 1	gene	biological_process-&-1&-GO:0046620-&&-regulation of organ growth-%%-GO:0000819-&&-sister chromatid segregation-%%-GO:0001828-&&-inner cell mass cellular morphogenesis-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0035329-&&-hippo signaling-%%-GO:0001827-&&-inner cell mass cell fate commitment-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:LATS1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	LATS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LATS1	0.42063755	0.07594937	81	4	FALSE	LATS1	LATS1	122.0759494	0	80	0	0.77044273	FALSE	1	LATS1	463932	0.03128854
789492	taxon:9606	2.43075469	3.84E-04	175346	1902	CTR9 homolog, Paf1/RNA polymerase II complex component	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0001826-&&-inner cell mass cell differentiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:2001162-&&-positive regulation of histone H3-K79 methylation-%%-GO:2000653-&&-regulation of genetic imprinting-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0001832-&&-blastocyst growth-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0042169-&&-SH2 domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0000993-&&-RNA polymerase II core binding	G:9606:CTR9				CTR9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTR9	0.41139487	0.11141975	81	4	FALSE	CTR9	CTR9	145.8888889	0	81	0	0.76154089	FALSE	0	CTR9	554678	0.04102019
789629	taxon:9606	2.54829053	1.96E-04	175030	1902	abl interactor 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0001756-&&-somitogenesis-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005622-&&-intracellular-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031209-&&-SCAR complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:ABI1				ABI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABI1	0.39241993	0.11100292	81	4	FALSE	ABI1	ABI1	101.721519	0	80	0	0.74195158	FALSE	1	ABI1	265254	0.03592164
789856	taxon:9606	2.43674177	8.86E-05	174501	1902	EBNA1 binding protein 2	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042273-&&-ribosomal large subunit biogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:EBNA1BP2				EBNA1BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EBNA1BP2	0.41038407	0.27253086	81	4	FALSE	EBNA1BP2	EBNA1BP2	192.2716049	0	81	0	0.76054304	FALSE	0	EBNA1BP2	209606	0.05443497
790262	taxon:9606	2.48668662	4.54E-04	173481	1902	NudC domain containing 3	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0032502-&&-developmental process-%%-GO:0006457-&&-protein folding-%%-GO:1905793-&&-protein localization to pericentriolar material|cellular_component-&-1&-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:NUDCD3				NUDCD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDCD3	0.40214154	0.04074074	81	4	FALSE	NUDCD3	NUDCD3	84.22222222	0	81	0	0.7522189	FALSE	0	NUDCD3	452256	0.02613002
790386	taxon:9606	2.46856783	1.55E-04	173148	1902	pleckstrin homology like domain family A member 3	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding	G:9606:PHLDA3				PHLDA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLDA3	0.40509318	0.04706264	81	4	FALSE	PHLDA3	PHLDA3	102.721519	0	80	0	0.7552387	FALSE	1	PHLDA3	239026	0.03080435
791811	taxon:9606	2.37277454	2.78E-04	166766	1902	microtubule associated protein 1 light chain 3 alpha	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0000422-&&-mitophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0043278-&&-response to morphine-%%-GO:0010040-&&-response to iron(II) ion|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0044754-&&-autolysosome-%%-GO:0005829-&&-cytosol-%%-GO:0005770-&&-late endosome-%%-GO:0005874-&&-microtubule-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:MAP1LC3A			KEGG-&-1&-hsa04216-&&-Ferroptosis	MAP1LC3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1LC3A	0.42144754	0.08888889	81	4	FALSE	MAP1LC3A	MAP1LC3A	135.0617284	0	81	0	0.77120424	FALSE	0	MAP1LC3A	373444	0.03452183
792068	taxon:9606	2.43012447	2.45E-04	182667	1902	BUB1 mitotic checkpoint serine/threonine kinase B	gene	biological_process-&-1&-GO:0034501-&&-protein localization to kinetochore-%%-GO:0006915-&&-apoptotic process-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0051233-&&-spindle midzone-%%-GO:0000778-&&-condensed nuclear chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0000940-&&-condensed chromosome outer kinetochore|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:BUB1B			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	BUB1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB1B	0.41150156	0.12041545	81	4	FALSE	BUB1B	BUB1B	135.7468354	0	80	0	0.76164592	FALSE	1	BUB1B	354662	0.03798531
792610	taxon:9606	2.35118954	2.56E-04	181726	1902	dual specificity tyrosine phosphorylation regulated kinase 1A	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0090312-&&-positive regulation of protein deacetylation-%%-GO:0007399-&&-nervous system development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0007623-&&-circadian rhythm-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0048156-&&-tau protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:DYRK1A				DYRK1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYRK1A	0.42531663	0.19344369	81	4	FALSE	DYRK1A	DYRK1A	221.0886076	0	80	0	0.77480174	FALSE	1	DYRK1A	445596	0.05441916
792866	taxon:9606	2.42413739	2.30E-04	181248	1902	estrogen related receptor beta	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:ESRRB			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	ESRRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESRRB	0.41251787	0.09783951	81	4	FALSE	ESRRB	ESRRB	145.2962963	0	81	0	0.76264377	FALSE	0	ESRRB	355516	0.04033951
792914	taxon:9606	2.45139436	2.15E-04	181161	1902	GRB2 associated binding protein 1	gene	biological_process-&-1&-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0008544-&&-epidermis development-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0035728-&&-response to hepatocyte growth factor|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:GAB1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAB1	0.4079311	0.16790123	81	4	FALSE	GAB1	GAB1	115.4938272	0	81	0	0.75810094	FALSE	0	GAB1	304728	0.03372707
793276	taxon:9606	2.37119899	1.56E-04	180387	1902	histone cluster 1 H1 family member c	gene	biological_process-&-1&-GO:0016584-&&-nucleosome positioning-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0080182-&&-histone H3-K4 trimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H1C				HIST1H1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1C	0.42172757	0.22530864	81	4	FALSE	HIST1H1C	HIST1H1C	256.8395062	0	81	0	0.77146683	FALSE	0	HIST1H1C	355534	0.0652508
793367	taxon:9606	2.33874271	1.46E-04	180234	1902	heterogeneous nuclear ribonucleoprotein H3	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPH3				HNRNPH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPH3	0.42758017	0.28562155	81	4	FALSE	HNRNPH3	HNRNPH3	251.3797468	0	80	0	0.77687621	FALSE	1	HNRNPH3	283340	0.06077235
787140	taxon:9606	2.5456121	2.79E-04	179993	1902	DNA ligase 4	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006266-&&-DNA ligation-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0000012-&&-single strand break repair-%%-GO:0045190-&&-isotype switching-%%-GO:0051301-&&-cell division-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0033153-&&-T cell receptor V(D)J recombination-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0051276-&&-chromosome organization-%%-GO:0033152-&&-immunoglobulin V(D)J recombination-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0007417-&&-central nervous system development-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0007049-&&-cell cycle-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051102-&&-DNA ligation involved in DNA recombination-%%-GO:0097680-&&-double-strand break repair via classical nonhomologous end joining-%%-GO:0010165-&&-response to X-ray-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0033151-&&-V(D)J recombination-%%-GO:2001252-&&-positive regulation of chromosome organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0071285-&&-cellular response to lithium ion|cellular_component-&-1&-GO:0032807-&&-DNA ligase IV complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005958-&&-DNA-dependent protein kinase-DNA ligase 4 complex-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0070419-&&-nonhomologous end joining complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016874-&&-ligase activity-%%-GO:0003910-&&-DNA ligase (ATP) activity	G:9606:LIG4			KEGG-&-1&-hsa03450-&&-Non-homologous end-joining	LIG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIG4	0.39283283	0.03417722	80	4	FALSE	LIG4	LIG4	86.9375	0	80	0	0.74239798	FALSE	0	LIG4	319512	0.03076855
787511	taxon:9606	2.44162597	2.09E-04	179309	1902	N-methylpurine DNA glycosylase	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0006307-&&-DNA dealkylation involved in DNA repair-%%-GO:0045007-&&-depurination|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003905-&&-alkylbase DNA N-glycosylase activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0052821-&&-DNA-7-methyladenine glycosylase activity-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0008725-&&-DNA-3-methyladenine glycosylase activity-%%-GO:0052822-&&-DNA-3-methylguanine glycosylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043916-&&-DNA-7-methylguanine glycosylase activity	G:9606:MPG			KEGG-&-1&-hsa03410-&&-Base excision repair	MPG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPG	0.40956314	0.06227106	80	4	FALSE	MPG	MPG	130.1410256	0	79	0	0.75972901	FALSE	1	MPG	321324	0.03722795
788852	taxon:9606	2.43658421	1.89E-04	176748	1902	vav guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008361-&&-regulation of cell size-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity	G:9606:VAV1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04660-&&-T cell receptor signaling pathway	VAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAV1	0.4104106	0.18132911	80	4	FALSE	VAV1	VAV1	134.5875	0	80	0	0.7605693	FALSE	0	VAV1	319264	0.03829681
789036	taxon:9606	2.37403498	1.91E-04	176313	1902	axin 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0060272-&&-embryonic skeletal joint morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0021881-&&-Wnt-activated signaling pathway involved in forebrain neuron fate commitment-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0021797-&&-forebrain anterior/posterior pattern specification-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030910-&&-olfactory placode formation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1904885-&&-beta-catenin destruction complex assembly-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0048320-&&-axial mesoderm formation-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060823-&&-canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0055001-&&-muscle cell development-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0001743-&&-optic placode formation-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0019899-&&-enzyme binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding	G:9606:AXIN1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04934-&&-Cushing syndrome-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05226-&&-Gastric cancer	AXIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AXIN1	0.42122379	0.12487512	80	4	FALSE	AXIN1	AXIN1	147.6923077	0	79	0	0.77099417	FALSE	1	AXIN1	316346	0.03772473
789348	taxon:9606	2.32897432	2.08E-04	175690	1902	apoptosis inducing factor mitochondria associated 1	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1904045-&&-cellular response to aldosterone-%%-GO:1902510-&&-regulation of apoptotic DNA fragmentation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0030261-&&-chromosome condensation-%%-GO:0071732-&&-cellular response to nitric oxide|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0071949-&&-FAD binding-%%-GO:0016651-&&-oxidoreductase activity, acting on NAD(P)H-%%-GO:0016174-&&-NAD(P)H oxidase activity-%%-GO:0046983-&&-protein dimerization activity	G:9606:AIFM1			KEGG-&-1&-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis	AIFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIFM1	0.42937356	0.06959707	80	4	FALSE	AIFM1	AIFM1	209.4615385	0	79	0	0.77850428	FALSE	1	AIFM1	473174	0.04982975
789490	taxon:9606	2.51173783	2.03E-04	175349	1902	mortality factor 4 like 2	gene	biological_process-&-1&-GO:0043967-&&-histone H4 acetylation-%%-GO:0040008-&&-regulation of growth-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0016575-&&-histone deacetylation-%%-GO:0051155-&&-positive regulation of striated muscle cell differentiation-%%-GO:0006281-&&-DNA repair-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MORF4L2				MORF4L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MORF4L2	0.39813072	0.11360759	80	4	FALSE	MORF4L2	MORF4L2	125.6375	0	80	0	0.7480437	FALSE	0	MORF4L2	324294	0.04093984
789606	taxon:9606	2.40491571	3.33E-04	175078	1902	WD repeat domain 1	gene	biological_process-&-1&-GO:0042247-&&-establishment of planar polarity of follicular epithelium-%%-GO:1990266-&&-neutrophil migration-%%-GO:0030043-&&-actin filament fragmentation-%%-GO:0030865-&&-cortical cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0030220-&&-platelet formation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0040011-&&-locomotion-%%-GO:0030834-&&-regulation of actin filament depolymerization-%%-GO:0045199-&&-maintenance of epithelial cell apical/basal polarity-%%-GO:0043297-&&-apical junction assembly-%%-GO:0030836-&&-positive regulation of actin filament depolymerization-%%-GO:0048713-&&-regulation of oligodendrocyte differentiation|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0002102-&&-podosome-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0042643-&&-actomyosin, actin portion-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0051015-&&-actin filament binding	G:9606:WDR1				WDR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR1	0.41581499	0.12056962	80	4	FALSE	WDR1	WDR1	137.4875	0	80	0	0.76584738	FALSE	0	WDR1	459906	0.03694235
790210	taxon:9606	2.39829841	2.75E-04	173635	1902	erythrocyte membrane protein band 4.1 like 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0002175-&&-protein localization to paranode region of axon-%%-GO:0030865-&&-cortical cytoskeleton organization-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0030913-&&-paranodal junction assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071205-&&-protein localization to juxtaparanode region of axon-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0008150-&&-biological_process-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0043217-&&-myelin maintenance-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030673-&&-axolemma-%%-GO:0033270-&&-paranode region of axon-%%-GO:0005829-&&-cytosol-%%-GO:0044224-&&-juxtaparanode region of axon|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:EPB41L3				EPB41L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41L3	0.41696229	0.1085443	80	4	FALSE	EPB41L3	EPB41L3	147.1875	0	80	0	0.76695027	FALSE	0	EPB41L3	397794	0.03901816
790419	taxon:9606	2.40412793	2.68E-04	173049	1902	FK506 binding protein 8	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006915-&&-apoptotic process-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0016032-&&-viral process-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0043010-&&-camera-type eye development-%%-GO:0001708-&&-cell fate specification-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0046872-&&-metal ion binding	G:9606:FKBP8				FKBP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP8	0.41595124	0.19014319	80	4	FALSE	FKBP8	FKBP8	139.3717949	0	79	0	0.76597868	FALSE	1	FKBP8	401692	0.03729136
792118	taxon:9606	2.29825114	2.74E-04	182573	1902	coatomer protein complex subunit beta 1	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0016032-&&-viral process-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:COPB1				COPB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPB1	0.43511346	0.11821512	80	4	FALSE	COPB1	COPB1	194.0897436	0	79	0	0.78362481	FALSE	1	COPB1	466702	0.04416992
792952	taxon:9606	2.50181188	2.83E-05	164707	1902	ribosomal protein L10 like	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005844-&&-polysome-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL10L			KEGG-&-1&-hsa03010-&&-Ribosome	RPL10L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL10L	0.39971031	0.70031646	80	4	FALSE	RPL10L	RPL10L	205.9875	0	80	0	0.74969802	FALSE	0	RPL10L	69646	0.06576868
793303	taxon:9606	2.36442414	4.79E-04	180345	1902	HCK proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0007498-&&-mesoderm development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045728-&&-respiratory burst after phagocytosis-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0002758-&&-innate immune response-activating signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043299-&&-leukocyte degranulation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0002522-&&-leukocyte migration involved in immune response-%%-GO:0016032-&&-viral process-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005901-&&-caveola-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding	G:9606:HCK			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HCK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCK	0.42293596	0.13886114	80	4	FALSE	HCK	HCK	135.4358974	0	79	0	0.77259598	FALSE	1	HCK	717020	0.03396182
787729	taxon:9606	2.32850165	2.19E-04	178861	1902	RNA polymerase II subunit B	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032549-&&-ribonucleoside binding-%%-GO:0046872-&&-metal ion binding	G:9606:POLR2B			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2B	0.42946072	0.16098669	79	4	FALSE	POLR2B	POLR2B	188.8607595	0	79	0	0.77858306	FALSE	0	POLR2B	428706	0.04478557
787730	taxon:9606	2.40318261	1.90E-04	178860	1902	RNA polymerase II subunit C	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:POLR2C			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2C	0.41611486	0.15755297	79	4	FALSE	POLR2C	POLR2C	147.5584416	0	78	0	0.76613623	FALSE	1	POLR2C	348306	0.03941916
787736	taxon:9606	2.3812825	1.96E-04	178858	1902	RNA polymerase II subunit E	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0016032-&&-viral process-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0005515-&&-protein binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR2E			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2E	0.41994178	0.183527	79	4	FALSE	POLR2E	POLR2E	183.3116883	0	78	0	0.76978625	FALSE	1	POLR2E	381004	0.04724407
788376	taxon:9606	2.38096739	1.75E-04	177780	1902	single stranded DNA binding protein 1	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0070584-&&-mitochondrion morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:SSBP1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03440-&&-Homologous recombination-%%-hsa03030-&&-DNA replication	SSBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSBP1	0.41999735	0.13602187	79	4	FALSE	SSBP1	SSBP1	216.1168831	0	78	0	0.76983877	FALSE	1	SSBP1	379934	0.0555899
788494	taxon:9606	2.33433118	1.24E-04	177554	1902	small nuclear ribonucleoprotein polypeptide A	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1900363-&&-regulation of mRNA polyadenylation|cellular_component-&-1&-GO:0005685-&&-U1 snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035614-&&-snRNA stem-loop binding-%%-GO:1990446-&&-U1 snRNP binding	G:9606:SNRPA			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPA	0.42838823	0.22932331	79	4	FALSE	SNRPA	SNRPA	243.1298701	0	78	0	0.77761147	FALSE	1	SNRPA	261538	0.05832315
788674	taxon:9606	2.41247834	5.64E-04	177216	1902	tight junction protein 1	gene	biological_process-&-1&-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0035329-&&-hippo signaling-%%-GO:1901350-&&-cell-cell signaling involved in cell-cell junction organization-%%-GO:0007043-&&-cell-cell junction assembly|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005921-&&-gap junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043296-&&-apical junction complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding	G:9606:TJP1	TJP1	TRUE	KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05132-&&-Salmonella infection-%%-hsa04530-&&-Tight junction-%%-hsa04520-&&-Adherens junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection	TJP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TJP1	0.41451149	0.07758031	79	4	FALSE	TJP1	TJP1	148.7532468	0	78	0	0.76458694	FALSE	1	TJP1	702100	0.04043347
788710	taxon:9606	2.31447928	4.91E-04	177137	1902	triosephosphate isomerase 1	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0019563-&&-glycerol catabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046166-&&-glyceraldehyde-3-phosphate biosynthetic process-%%-GO:0006096-&&-glycolytic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004807-&&-triose-phosphate isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TPI1			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00562-&&-Inositol phosphate metabolism	TPI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPI1	0.43206263	0.14559125	79	4	FALSE	TPI1	TPI1	202.0909091	0	78	0	0.78092012	FALSE	1	TPI1	720268	0.04694817
788716	taxon:9606	2.35890972	1.02E-04	177129	1902	translocated promoter region, nuclear basket protein	gene	biological_process-&-1&-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0070849-&&-response to epidermal growth factor-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0010965-&&-regulation of mitotic sister chromatid separation-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0006404-&&-RNA import into nucleus-%%-GO:0031453-&&-positive regulation of heterochromatin assembly-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0008150-&&-biological_process-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046832-&&-negative regulation of RNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0000189-&&-MAPK import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006999-&&-nuclear pore organization-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0034605-&&-cellular response to heat-%%-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0019083-&&-viral transcription-%%-GO:0043578-&&-nuclear matrix organization-%%-GO:0031990-&&-mRNA export from nucleus in response to heat stress-%%-GO:0016032-&&-viral process-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0042306-&&-regulation of protein import into nucleus|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005737-&&-cytoplasm-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005635-&&-nuclear envelope-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043495-&&-protein anchor-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0005215-&&-transporter activity-%%-GO:0003674-&&-molecular_function-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0015631-&&-tubulin binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:TPR			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	TPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPR	0.42392466	0.17624148	79	4	FALSE	TPR	TPR	215	0	79	0	0.77351505	FALSE	0	TPR	245352	0.05362302
789164	taxon:9606	2.55916181	3.53E-04	176067	1902	unc-119 lipid binding chaperone	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006897-&&-endocytosis-%%-GO:0007602-&&-phototransduction-%%-GO:1900186-&&-negative regulation of clathrin-dependent endocytosis-%%-GO:2001287-&&-negative regulation of caveolin-mediated endocytosis-%%-GO:0042953-&&-lipoprotein transport|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0051233-&&-spindle midzone-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008289-&&-lipid binding-%%-GO:0005515-&&-protein binding	G:9606:UNC119				UNC119	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC119	0.39075294	0.01914963	79	4	FALSE	UNC119	UNC119	75.84810127	0	79	0	0.7401397	FALSE	0	UNC119	393996	0.02767741
789228	taxon:9606	2.30959508	1.48E-04	175962	1902	KH-type splicing regulatory protein	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:2000628-&&-regulation of miRNA metabolic process-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0008380-&&-RNA splicing-%%-GO:0061014-&&-positive regulation of mRNA catabolic process|cellular_component-&-1&-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:KHSRP				KHSRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KHSRP	0.43297633	0.1415125	79	4	FALSE	KHSRP	KHSRP	258.6962025	0	79	0	0.78173415	FALSE	0	KHSRP	392354	0.0599381
789481	taxon:9606	2.48180243	3.56E-04	175370	1902	TNF receptor associated factor 4	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030323-&&-respiratory tube development-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0050699-&&-WW domain binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TRAF4			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	TRAF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF4	0.40293296	0.06151743	79	5	FALSE	TRAF4	TRAF4	106.6623377	0	78	0	0.75303293	FALSE	1	TRAF4	474360	0.03292906
789603	taxon:9606	2.44666772	3.24E-04	175086	1902	RNA binding motif protein 8A	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:RBM8A	RBM8A	TRUE	KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	RBM8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM8A	0.40871917	0.10423787	79	4	FALSE	RBM8A	RBM8A	136.2857143	0	78	0	0.75888871	FALSE	1	RBM8A	465604	0.03937792
790007	taxon:9606	2.44351662	1.27E-04	174126	1902	zinc finger and BTB domain containing 1	gene	biological_process-&-1&-GO:2000176-&&-positive regulation of pro-T cell differentiation-%%-GO:0045087-&&-innate immune response-%%-GO:0002711-&&-positive regulation of T cell mediated immunity-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0048538-&&-thymus development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006281-&&-DNA repair-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032825-&&-positive regulation of natural killer cell differentiation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZBTB1				ZBTB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB1	0.40924624	0.14410906	79	4	FALSE	ZBTB1	ZBTB1	157.6329114	0	79	0	0.7594139	FALSE	0	ZBTB1	220062	0.04513233
790059	taxon:9606	2.40475815	1.42E-04	173982	1902	lysine acetyltransferase 7	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043984-&&-histone H4-K16 acetylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:KAT7				KAT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT7	0.41584223	0.16293411	79	4	FALSE	KAT7	KAT7	206.9367089	0	79	0	0.76587364	FALSE	0	KAT7	361020	0.05532052
790598	taxon:9606	2.30943753	3.04E-04	172001	1902	argonaute 2, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0006412-&&-translation-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035087-&&-siRNA loading onto RISC involved in RNA interference-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:1905618-&&-positive regulation of miRNA mediated inhibition of translation-%%-GO:0009791-&&-post-embryonic development-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0045947-&&-negative regulation of translational initiation|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0035068-&&-micro-ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0005844-&&-polysome-%%-GO:0030425-&&-dendrite-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0035197-&&-siRNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0090624-&&-endoribonuclease activity, cleaving miRNA-paired mRNA-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0070551-&&-endoribonuclease activity, cleaving siRNA-paired mRNA-%%-GO:0001047-&&-core promoter binding-%%-GO:0098808-&&-mRNA cap binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:AGO2				AGO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO2	0.43300587	0.11262577	79	4	FALSE	AGO2	AGO2	191.3417722	0	79	0	0.78176041	FALSE	0	AGO2	493302	0.04421165
790766	taxon:9606	2.49771546	1.79E-04	171291	1902	ninein	gene	biological_process-&-1&-GO:0051642-&&-centrosome localization-%%-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0090222-&&-centrosome-templated microtubule nucleation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0097539-&&-ciliary transition fiber-%%-GO:0005814-&&-centriole-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0036449-&&-microtubule minus-end-%%-GO:0000922-&&-spindle pole-%%-GO:0097431-&&-mitotic spindle pole|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NIN				NIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NIN	0.40036586	0.10184552	79	4	FALSE	NIN	NIN	97.76623377	0	78	0	0.75038076	FALSE	1	NIN	260868	0.03079146
791892	taxon:9606	2.32692611	2.23E-04	182916	1902	adaptor related protein complex 2 alpha 1 subunit	gene	biological_process-&-1&-GO:0006895-&&-Golgi to endosome transport-%%-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1900126-&&-negative regulation of hyaluronan biosynthetic process-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006897-&&-endocytosis-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0032433-&&-filopodium tip-%%-GO:0005829-&&-cytosol-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0036020-&&-endolysosome membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0035615-&&-clathrin adaptor activity	G:9606:AP2A1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2A1	0.42975151	0.19376826	79	4	FALSE	AP2A1	AP2A1	200.4303798	0	79	0	0.77884565	FALSE	0	AP2A1	432774	0.04760516
792006	taxon:9606	2.30329289	2.44E-04	182742	1902	BCR, RhoGEF and GTPase activating protein	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0060268-&&-negative regulation of respiratory burst-%%-GO:0043314-&&-negative regulation of neutrophil degranulation-%%-GO:0051171-&&-regulation of nitrogen compound metabolic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0003014-&&-renal system process-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060313-&&-negative regulation of blood vessel remodeling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0002692-&&-negative regulation of cellular extravasation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0065002-&&-intracellular protein transmembrane transport-%%-GO:0007165-&&-signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0050885-&&-neuromuscular process controlling balance|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005524-&&-ATP binding	G:9606:BCR			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	BCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCR	0.43416102	0.16267943	79	4	FALSE	BCR	BCR	190.0909091	0	78	0	0.78278452	FALSE	1	BCR	422110	0.04354294
793353	taxon:9606	2.41421144	2.74E-04	180248	1902	hepatocyte nuclear factor 4 alpha	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006591-&&-ornithine metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:2000189-&&-positive regulation of cholesterol homeostasis-%%-GO:0010470-&&-regulation of gastrulation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0055091-&&-phospholipid homeostasis-%%-GO:0007548-&&-sex differentiation-%%-GO:0009749-&&-response to glucose-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:HNF4A			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04950-&&-Maturity onset diabetes of the young	HNF4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNF4A	0.41421393	0.14935065	79	4	FALSE	HNF4A	HNF4A	144.038961	0	78	0	0.76429809	FALSE	1	HNF4A	370972	0.03915524
787263	taxon:9606	2.56152513	2.21E-04	179782	1902	Janus kinase 3	gene	biological_process-&-1&-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0002731-&&-negative regulation of dendritic cell cytokine production-%%-GO:0070232-&&-regulation of T cell apoptotic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0071104-&&-response to interleukin-9-%%-GO:0006954-&&-inflammatory response-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045626-&&-negative regulation of T-helper 1 cell differentiation-%%-GO:0050868-&&-negative regulation of T cell activation-%%-GO:0070670-&&-response to interleukin-4-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045221-&&-negative regulation of FasL biosynthetic process-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0070669-&&-response to interleukin-2-%%-GO:0016477-&&-cell migration-%%-GO:0002250-&&-adaptive immune response-%%-GO:0000165-&&-MAPK cascade-%%-GO:0070672-&&-response to interleukin-15|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding	G:9606:JAK3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04217-&&-Necroptosis	JAK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAK3	0.39039242	0.08175439	78	4	FALSE	JAK3	JAK3	91.38157895	0	77	0	0.73974581	FALSE	1	JAK3	274330	0.03337636
788268	taxon:9606	2.36048527	2.89E-04	177968	1902	ribosomal protein S6 kinase A1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0043555-&&-regulation of translation in response to stress-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0072574-&&-hepatocyte proliferation-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:RPS6KA1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04150-&&-mTOR signaling pathway	RPS6KA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA1	0.4236417	0.08701754	78	4	FALSE	RPS6KA1	RPS6KA1	135.3684211	0	77	0	0.77325246	FALSE	1	RPS6KA1	402012	0.03379373
788309	taxon:9606	2.52843863	2.93E-04	177908	1902	sortilin 1	gene	biological_process-&-1&-GO:0032868-&&-response to insulin-%%-GO:0016050-&&-vesicle organization-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0001503-&&-ossification-%%-GO:0006897-&&-endocytosis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0046323-&&-glucose import-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0051005-&&-negative regulation of lipoprotein lipase activity-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0014902-&&-myotube differentiation-%%-GO:0006895-&&-Golgi to endosome transport-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007275-&&-multicellular organism development-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:1904037-&&-positive regulation of epithelial cell apoptotic process-%%-GO:0032509-&&-endosome transport via multivesicular body sorting pathway|cellular_component-&-1&-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0010008-&&-endosome membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0043025-&&-neuronal cell body-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030379-&&-neurotensin receptor activity, non-G-protein coupled-%%-GO:0048406-&&-nerve growth factor binding-%%-GO:0010465-&&-nerve growth factor receptor activity-%%-GO:0019899-&&-enzyme binding	G:9606:SORT1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa04142-&&-Lysosome	SORT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORT1	0.395501	0.02997003	78	4	FALSE	SORT1	SORT1	79.32051282	0	78	0	0.74526023	FALSE	0	SORT1	319458	0.02686908
788528	taxon:9606	2.48416575	2.22E-04	177497	1902	thyroid hormone receptor, alpha	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0017055-&&-negative regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007611-&&-learning or memory-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0008050-&&-female courtship behavior-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0050994-&&-regulation of lipid catabolic process-%%-GO:2000143-&&-negative regulation of DNA-templated transcription, initiation-%%-GO:0030878-&&-thyroid gland development-%%-GO:0001503-&&-ossification-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0033032-&&-regulation of myeloid cell apoptotic process-%%-GO:0045925-&&-positive regulation of female receptivity-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0002155-&&-regulation of thyroid hormone mediated signaling pathway-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0001502-&&-cartilage condensation-%%-GO:0060509-&&-Type I pneumocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0002153-&&-steroid receptor RNA activator RNA binding-%%-GO:0070324-&&-thyroid hormone binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:THRA			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	THRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRA	0.40254963	0.11894737	78	4	FALSE	THRA	THRA	128.1973684	0	77	0	0.75263904	FALSE	1	THRA	324828	0.03962422
789005	taxon:9606	2.44587994	9.09E-05	176409	1902	acidic nuclear phosphoprotein 32 family member A	gene	biological_process-&-1&-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ANP32A				ANP32A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANP32A	0.40885081	0.18614719	78	4	FALSE	ANP32A	ANP32A	200.3333333	0	78	0	0.75902001	FALSE	0	ANP32A	246276	0.05747342
789099	taxon:9606	2.35386797	9.94E-05	176198	1902	DEAD-box helicase 18	gene	biological_process-&-1&-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:DDX18				DDX18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX18	0.42483266	0.32667333	78	4	FALSE	DDX18	DDX18	228.0512821	0	78	0	0.77435534	FALSE	0	DDX18	213022	0.05641723
789847	taxon:9606	2.54277611	9.94E-05	174516	1902	chromobox 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0001939-&&-female pronucleus-%%-GO:0005819-&&-spindle-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001940-&&-male pronucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0010369-&&-chromocenter-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:1990226-&&-histone methyltransferase binding	G:9606:CBX1				CBX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBX1	0.39327096	0.30666667	78	4	FALSE	CBX1	CBX1	193.8289474	0	77	0	0.74287065	FALSE	1	CBX1	219706	0.06696705
790359	taxon:9606	2.41232078	1.50E-04	173221	1902	Ski2 like RNA helicase 2	gene	biological_process-&-1&-GO:0006401-&&-RNA catabolic process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:SKIV2L2			KEGG-&-1&-hsa03018-&&-RNA degradation	SKIV2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKIV2L2	0.41453857	0.15384615	78	4	FALSE	SKIV2L2	SKIV2L2	194.9358974	0	78	0	0.7646132	FALSE	0	SKIV2L2	287156	0.05265691
790383	taxon:9606	2.40018907	2.12E-04	173156	1902	coronin 1C	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0006909-&&-phagocytosis-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:1900024-&&-regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0016600-&&-flotillin complex-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding	G:9606:CORO1C				CORO1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CORO1C	0.41663385	0.13220113	78	4	FALSE	CORO1C	CORO1C	162.5769231	0	78	0	0.76663516	FALSE	0	CORO1C	358206	0.0433239
792063	taxon:9606	2.53442571	2.85E-04	182669	1902	BUB1 mitotic checkpoint serine/threonine kinase	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007063-&&-regulation of sister chromatid cohesion-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016032-&&-viral process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051754-&&-meiotic sister chromatid cohesion, centromeric-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0071173-&&-spindle assembly checkpoint-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:BUB1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	BUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB1	0.3945667	0.04421053	78	4	FALSE	BUB1	BUB1	85.64473684	0	77	0	0.74426238	FALSE	1	BUB1	359560	0.02933312
792078	taxon:9606	2.60894911	2.11E-04	182655	1902	CLN3, battenin	gene	biological_process-&-1&-GO:0042133-&&-neurotransmitter metabolic process-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0001575-&&-globoside metabolic process-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0061024-&&-membrane organization-%%-GO:0006678-&&-glucosylceramide metabolic process-%%-GO:0016485-&&-protein processing-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0015809-&&-arginine transport-%%-GO:0035752-&&-lysosomal lumen pH elevation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006681-&&-galactosylceramide metabolic process-%%-GO:0006684-&&-sphingomyelin metabolic process-%%-GO:0001508-&&-action potential-%%-GO:0016236-&&-macroautophagy-%%-GO:0007042-&&-lysosomal lumen acidification-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0008306-&&-associative learning-%%-GO:0007040-&&-lysosome organization-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005795-&&-Golgi stack-%%-GO:0005739-&&-mitochondrion-%%-GO:0005764-&&-lysosome-%%-GO:0005776-&&-autophagosome-%%-GO:0005901-&&-caveola-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005770-&&-late endosome-%%-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:CLN3			KEGG-&-1&-hsa04142-&&-Lysosome	CLN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLN3	0.38329609	0.04395604	78	4	FALSE	CLN3	CLN3	76.01282051	0	78	0	0.73184182	FALSE	0	CLN3	290838	0.03111673
792384	taxon:9606	2.44840082	5.57E-05	165731	1902	FtsJ homolog 3	gene	biological_process-&-1&-GO:0031167-&&-rRNA methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008649-&&-rRNA methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:FTSJ3				FTSJ3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTSJ3	0.40842986	0.28138528	78	4	FALSE	FTSJ3	FTSJ3	190.9102564	0	78	0	0.75859986	FALSE	0	FTSJ3	145380	0.05506497
792664	taxon:9606	2.38506381	2.21E-04	181596	1902	DAB2, clathrin adaptor protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0015031-&&-protein transport-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:2000370-&&-positive regulation of clathrin-dependent endocytosis-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0035026-&&-leading edge cell differentiation-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045807-&&-positive regulation of endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070022-&&-transforming growth factor beta receptor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0038024-&&-cargo receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:DAB2			KEGG-&-1&-hsa04144-&&-Endocytosis	DAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAB2	0.41927599	0.12820513	78	4	FALSE	DAB2	DAB2	147.7820513	0	78	0	0.76915603	FALSE	0	DAB2	366008	0.03855187
793066	taxon:9606	2.38742713	1.27E-04	180814	1902	mutS homolog 6	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0006298-&&-mismatch repair-%%-GO:0045190-&&-isotype switching-%%-GO:0000710-&&-meiotic mismatch repair-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016447-&&-somatic recombination of immunoglobulin gene segments-%%-GO:0006281-&&-DNA repair-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0009411-&&-response to UV-%%-GO:0016032-&&-viral process-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0032301-&&-MutSalpha complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0032143-&&-single thymine insertion binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0043531-&&-ADP binding-%%-GO:0032137-&&-guanine/thymine mispair binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0032405-&&-MutLalpha complex binding-%%-GO:0032142-&&-single guanine insertion binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:MSH6	MSH6	TRUE	KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	MSH6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSH6	0.41886095	0.15084915	78	4	FALSE	MSH6	MSH6	174.0128205	0	78	0	0.76876214	FALSE	0	MSH6	282818	0.04523005
788314	taxon:9606	2.40239483	1.33E-04	177900	1902	S100 calcium binding protein A9	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0032119-&&-sequestering of zinc ion-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0050832-&&-defense response to fungus-%%-GO:0002793-&&-positive regulation of peptide secretion-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006914-&&-autophagy-%%-GO:0006954-&&-inflammatory response-%%-GO:0070488-&&-neutrophil aggregation-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0001816-&&-cytokine production-%%-GO:0006417-&&-regulation of translation-%%-GO:0045113-&&-regulation of integrin biosynthetic process-%%-GO:0035606-&&-peptidyl-cysteine S-trans-nitrosylation-%%-GO:0032602-&&-chemokine production-%%-GO:0014002-&&-astrocyte development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0035662-&&-Toll-like receptor 4 binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016209-&&-antioxidant activity-%%-GO:0050544-&&-arachidonic acid binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0004871-&&-signal transducer activity	G:9606:S100A9			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	S100A9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A9	0.41625131	0.15891892	77	4	FALSE	S100A9	S100A9	172.8533333	0	76	0	0.76626753	FALSE	1	S100A9	265562	0.0462315
788745	taxon:9606	2.32393257	1.56E-04	177050	1902	DnaJ heat shock protein family (Hsp40) member C7	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DNAJC7				DNAJC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC7	0.43030508	0.14774775	77	4	FALSE	DNAJC7	DNAJC7	190.52	0	76	0	0.77934457	FALSE	1	DNAJC7	315576	0.04493198
788790	taxon:9606	2.46951316	5.40E-05	176885	1902	DEK proto-oncogene	gene	biological_process-&-1&-GO:2001032-&&-regulation of double-strand break repair via nonhomologous end joining-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0019079-&&-viral genome replication-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007165-&&-signal transduction-%%-GO:2000779-&&-regulation of double-strand break repair-%%-GO:0006338-&&-chromatin remodeling|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043292-&&-contractile fiber-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042393-&&-histone binding	G:9606:DEK				DEK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEK	0.40493811	0.29369369	77	4	FALSE	DEK	DEK	237.48	0	76	0	0.75508114	FALSE	1	DEK	166866	0.07129391
788971	taxon:9606	2.52260911	1.30E-04	176506	1902	CCHC-type zinc finger nucleic acid binding protein	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding	G:9606:CNBP	CNBP	TRUE		CNBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNBP	0.39641496	0.15789474	77	4	FALSE	CNBP	CNBP	183.4025974	0	77	0	0.74623182	FALSE	0	CNBP	263460	0.06092545
789161	taxon:9606	2.29289428	2.86E-04	176068	1902	DnaJ heat shock protein family (Hsp40) member A3	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0006457-&&-protein folding-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0009408-&&-response to heat-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0007569-&&-cell aging-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006264-&&-mitochondrial DNA replication|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005884-&&-actin filament-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:DNAJA3			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	DNAJA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA3	0.43613001	0.11483254	77	4	FALSE	DNAJA3	DNAJA3	200.4155844	0	77	0	0.78451762	FALSE	0	DNAJA3	490260	0.04528285
790065	taxon:9606	2.40334016	4.80E-04	173966	1902	ER lipid raft associated 2	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0045541-&&-negative regulation of cholesterol biosynthetic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0032933-&&-SREBP signaling pathway-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0015485-&&-cholesterol binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ERLIN2				ERLIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERLIN2	0.41608758	0.08544087	77	4	FALSE	ERLIN2	ERLIN2	137.7532468	0	77	0	0.76610997	FALSE	0	ERLIN2	629928	0.03695338
790685	taxon:9606	2.54624232	9.58E-05	171476	1902	bromodomain containing 7	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0090544-&&-BAF-type complex|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042393-&&-histone binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding	G:9606:BRD7			KEGG-&-1&-hsa05225-&&-Hepatocellular carcinoma	BRD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD7	0.3927356	0.20198223	77	4	FALSE	BRD7	BRD7	179.1298701	0	77	0	0.74229295	FALSE	0	BRD7	242120	0.06237023
791959	taxon:9606	2.29888136	3.54E-04	182804	1902	annexin A1	gene	biological_process-&-1&-GO:0044849-&&-estrous cycle-%%-GO:0042063-&&-gliogenesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0031394-&&-positive regulation of prostaglandin biosynthetic process-%%-GO:0071621-&&-granulocyte chemotaxis-%%-GO:0036292-&&-DNA rewinding-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0045629-&&-negative regulation of T-helper 2 cell differentiation-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0045920-&&-negative regulation of exocytosis-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0030850-&&-prostate gland development-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0045627-&&-positive regulation of T-helper 1 cell differentiation-%%-GO:1900138-&&-negative regulation of phospholipase A2 activity-%%-GO:2000483-&&-negative regulation of interleukin-8 secretion-%%-GO:0001780-&&-neutrophil homeostasis-%%-GO:0014839-&&-myoblast migration involved in skeletal muscle regeneration-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0046883-&&-regulation of hormone secretion-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0033031-&&-positive regulation of neutrophil apoptotic process-%%-GO:0006909-&&-phagocytosis-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0032355-&&-response to estradiol-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:0002685-&&-regulation of leukocyte migration-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0010165-&&-response to X-ray-%%-GO:0032652-&&-regulation of interleukin-1 production-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0045087-&&-innate immune response-%%-GO:0030073-&&-insulin secretion-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0070459-&&-prolactin secretion-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0031514-&&-motile cilium-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0001533-&&-cornified envelope-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0031313-&&-extrinsic component of endosome membrane-%%-GO:0043234-&&-protein complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001891-&&-phagocytic cup-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0042629-&&-mast cell granule-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019834-&&-phospholipase A2 inhibitor activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005102-&&-receptor binding-%%-GO:0036310-&&-annealing helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0005198-&&-structural molecule activity-%%-GO:0033676-&&-double-stranded DNA-dependent ATPase activity	G:9606:ANXA1				ANXA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA1	0.43499417	0.08475735	77	4	FALSE	ANXA1	ANXA1	201.3246753	0	77	0	0.78351977	FALSE	0	ANXA1	542522	0.04587501
791981	taxon:9606	2.30738932	1.61E-04	182778	1902	apurinic/apyrimidinic endodeoxyribonuclease 1	gene	biological_process-&-1&-GO:0006286-&&-base-excision repair, base-free sugar-phosphate removal-%%-GO:0006284-&&-base-excision repair-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006310-&&-DNA recombination-%%-GO:0000723-&&-telomere maintenance-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0080111-&&-DNA demethylation-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007568-&&-aging-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0004528-&&-phosphodiesterase I activity-%%-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0004519-&&-endonuclease activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0016890-&&-site-specific endodeoxyribonuclease activity, specific for altered base-%%-GO:0005515-&&-protein binding-%%-GO:0004523-&&-RNA-DNA hybrid ribonuclease activity-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0004844-&&-uracil DNA N-glycosylase activity-%%-GO:0008081-&&-phosphoric diester hydrolase activity-%%-GO:0008309-&&-double-stranded DNA exodeoxyribonuclease activity-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008311-&&-double-stranded DNA 3'-5' exodeoxyribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:APEX1			KEGG-&-1&-hsa03410-&&-Base excision repair	APEX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APEX1	0.43339024	0.12720721	77	4	FALSE	APEX1	APEX1	203.9866667	0	76	0	0.78210178	FALSE	1	APEX1	332912	0.04693517
792311	taxon:9606	2.61336064	8.58E-05	165863	1902	forkhead box Q1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:FOXQ1				FOXQ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXQ1	0.38264906	0.03485988	77	4	FALSE	FOXQ1	FOXQ1	80.67532468	0	77	0	0.73110656	FALSE	0	FOXQ1	153350	0.0328976
792562	taxon:9606	2.32582322	2.88E-04	181808	1902	serpin family H member 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0003433-&&-chondrocyte development involved in endochondral bone morphogenesis-%%-GO:0051604-&&-protein maturation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0032964-&&-collagen biosynthetic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005615-&&-extracellular space-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0003723-&&-RNA binding	G:9606:SERPINH1				SERPINH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINH1	0.42995529	0.08065619	77	4	FALSE	SERPINH1	SERPINH1	190.1428571	0	77	0	0.77902946	FALSE	0	SERPINH1	534082	0.04503149
792692	taxon:9606	2.40255239	2.07E-04	181553	1902	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit	gene	biological_process-&-1&-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0034097-&&-response to cytokine-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006486-&&-protein glycosylation-%%-GO:0042110-&&-T cell activation-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0035577-&&-azurophil granule membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004576-&&-oligosaccharyl transferase activity	G:9606:DDOST			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DDOST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDOST	0.41622401	0.16507177	77	4	FALSE	DDOST	DDOST	160.8701299	0	77	0	0.76624127	FALSE	0	DDOST	346236	0.04305946
793327	taxon:9606	2.42634315	2.80E-04	180315	1902	ubiquitin conjugating enzyme E2 K	gene	biological_process-&-1&-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0032433-&&-filopodium tip-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:UBE2K			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2K	0.41214286	0.10378378	77	4	FALSE	UBE2K	UBE2K	140.52	0	76	0	0.76227614	FALSE	1	UBE2K	402774	0.0389536
793357	taxon:9606	2.33622184	1.53E-04	180241	1902	heterogeneous nuclear ribonucleoprotein A/B	gene	biological_process-&-1&-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HNRNPAB				HNRNPAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPAB	0.42804154	0.24846206	77	4	FALSE	HNRNPAB	HNRNPAB	268.2077922	0	77	0	0.77729636	FALSE	0	HNRNPAB	306934	0.06451643
787186	taxon:9606	2.3979833	1.69E-04	179905	1902	SMAD family member 7	gene	biological_process-&-1&-GO:0034333-&&-adherens junction assembly-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:0022409-&&-positive regulation of cell-cell adhesion-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060373-&&-regulation of ventricular cardiac muscle cell membrane depolarization-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0001657-&&-ureteric bud development-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0030336-&&-negative regulation of cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016342-&&-catenin complex|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0005518-&&-collagen binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0030617-&&-transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	G:9606:SMAD7	SMAD7	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD7	0.41701708	0.1536468	76	4	FALSE	SMAD7	SMAD7	152.8108108	0	75	0	0.76700278	FALSE	1	SMAD7	306122	0.04045825
787395	taxon:9606	2.4578541	1.72E-04	179506	1902	myogenic differentiation 1	gene	biological_process-&-1&-GO:0048743-&&-positive regulation of skeletal muscle fiber development-%%-GO:0014904-&&-myotube cell development-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:2000818-&&-negative regulation of myoblast proliferation-%%-GO:0014908-&&-myotube differentiation involved in skeletal muscle regeneration-%%-GO:0043415-&&-positive regulation of skeletal muscle tissue regeneration-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007518-&&-myoblast fate determination-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043503-&&-skeletal muscle fiber adaptation-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0007517-&&-muscle organ development-%%-GO:0042693-&&-muscle cell fate commitment-%%-GO:0007520-&&-myoblast fusion-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0071453-&&-cellular response to oxygen levels-%%-GO:0045663-&&-positive regulation of myoblast differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0030016-&&-myofibril-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:MYOD1				MYOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOD1	0.40685897	0.19029989	76	4	FALSE	MYOD1	MYOD1	182.7702703	0	75	0	0.75702432	FALSE	1	MYOD1	324326	0.05358261
787404	taxon:9606	2.43910509	1.03E-04	179486	1902	nuclear autoantigenic sperm protein	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0043486-&&-histone exchange-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0015031-&&-protein transport-%%-GO:0008283-&&-cell proliferation-%%-GO:0006260-&&-DNA replication-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0033574-&&-response to testosterone-%%-GO:0001824-&&-blastocyst development-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding	G:9606:NASP				NASP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NASP	0.40998643	0.17333333	76	4	FALSE	NASP	NASP	209.381579	0	76	0	0.76014915	FALSE	0	NASP	284958	0.05967188
787447	taxon:9606	2.63321254	5.50E-05	179416	1902	methyl-CpG binding protein 2	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:2000820-&&-negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0021549-&&-cerebellum development-%%-GO:0051151-&&-negative regulation of smooth muscle cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042551-&&-neuron maturation-%%-GO:0019230-&&-proprioception-%%-GO:0007616-&&-long-term memory-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0046470-&&-phosphatidylcholine metabolic process-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0016571-&&-histone methylation-%%-GO:0006576-&&-cellular biogenic amine metabolic process-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0035176-&&-social behavior-%%-GO:0021591-&&-ventricular system development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032048-&&-cardiolipin metabolic process-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0006020-&&-inositol metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007416-&&-synapse assembly-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0031061-&&-negative regulation of histone methylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009405-&&-pathogenesis-%%-GO:0001964-&&-startle response-%%-GO:0016573-&&-histone acetylation-%%-GO:0002087-&&-regulation of respiratory gaseous exchange by neurological system process-%%-GO:0008542-&&-visual learning-%%-GO:0016358-&&-dendrite development-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0008211-&&-glucocorticoid metabolic process-%%-GO:0009791-&&-post-embryonic development-%%-GO:1900114-&&-positive regulation of histone H3-K9 trimethylation-%%-GO:0008104-&&-protein localization-%%-GO:0001662-&&-behavioral fear response-%%-GO:0001976-&&-neurological system process involved in regulation of systemic arterial blood pressure-%%-GO:0050432-&&-catecholamine secretion-%%-GO:0019233-&&-sensory perception of pain|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0010385-&&-double-stranded methylated DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0035197-&&-siRNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:MECP2				MECP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MECP2	0.37976426	0.21824561	76	4	FALSE	MECP2	MECP2	172.1578947	0	76	0	0.72779791	FALSE	0	MECP2	162142	0.07308079
787541	taxon:9606	2.44446195	2.37E-04	179217	1902	protein phosphatase 2 scaffold subunit Abeta	gene	biological_process-&-1&-GO:0060561-&&-apoptotic process involved in morphogenesis-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PPP2R1B			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R1B	0.40908798	0.10958904	76	4	FALSE	PPP2R1B	PPP2R1B	115.7432432	0	75	0	0.75925634	FALSE	1	PPP2R1B	320850	0.03322315
787706	taxon:9606	2.52560265	1.50E-04	162526	1902	histone cluster 1 H2B family member a	gene	biological_process-&-1&-GO:0031639-&&-plasminogen activation-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006954-&&-inflammatory response-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071674-&&-mononuclear cell migration-%%-GO:0035093-&&-spermatogenesis, exchange of chromosomal proteins|cellular_component-&-1&-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0000786-&&-nucleosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BA			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BA	0.3959451	0.11368421	76	4	FALSE	HIST1H2BA	HIST1H2BA	111.2894737	0	76	0	0.74573289	FALSE	0	HIST1H2BA	240036	0.03732411
787880	taxon:9606	2.47991177	9.78E-05	178663	1902	proteasome subunit beta 2	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB2			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB2	0.40324015	0.3877193	76	4	FALSE	PSMB2	PSMB2	152.2894737	0	76	0	0.75334804	FALSE	0	PSMB2	193658	0.04692239
788202	taxon:9606	2.37781629	2.42E-04	178094	1902	RB transcriptional corepressor like 1	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:RBL1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	RBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBL1	0.42055394	0.12180674	76	4	FALSE	RBL1	RBL1	154.2567568	0	75	0	0.77036395	FALSE	1	RBL1	373758	0.03955276
788322	taxon:9606	2.37687096	1.27E-04	177887	1902	scaffold attachment factor B	gene	biological_process-&-1&-GO:0050684-&&-regulation of mRNA processing-%%-GO:0006325-&&-chromatin organization-%%-GO:0040007-&&-growth-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SAFB				SAFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAFB	0.4207212	0.15964912	76	4	FALSE	SAFB	SAFB	181.2368421	0	76	0	0.77052151	FALSE	0	SAFB	271772	0.04634028
788792	taxon:9606	2.42713093	1.00E-04	176880	1902	DExD-box helicase 39B	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0001889-&&-liver development-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0000346-&&-transcription export complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005688-&&-U6 snRNP|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0008186-&&-RNA-dependent ATPase activity-%%-GO:0017070-&&-U6 snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0043008-&&-ATP-dependent protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:DDX39B			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa03015-&&-mRNA surveillance pathway	DDX39B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX39B	0.41200909	0.13957793	76	4	FALSE	DDX39B	DDX39B	191.8513514	0	75	0	0.76214485	FALSE	1	DDX39B	228112	0.05335113
788832	taxon:9606	2.40664881	3.63E-04	176790	1902	ubiquitin fusion degradation 1 like (yeast)	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036501-&&-UFD1-NPL4 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0036435-&&-K48-linked polyubiquitin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:UFD1L			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UFD1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFD1L	0.41551555	0.08385965	76	4	FALSE	UFD1L	UFD1L	126.5657895	0	76	0	0.76555853	FALSE	0	UFD1L	445652	0.03409349
789105	taxon:9606	2.4178352	1.19E-04	176185	1902	cyclin A1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0007141-&&-male meiosis I-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097123-&&-cyclin A1-CDK2 complex-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCNA1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04110-&&-Cell cycle-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	CCNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNA1	0.41359312	0.11514254	76	4	FALSE	CCNA1	CCNA1	152.1081081	0	75	0	0.76369413	FALSE	1	CCNA1	221190	0.04176938
789380	taxon:9606	2.44840082	3.24E-04	175623	1902	VAMP associated protein B and C	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0090114-&&-COPII-coated vesicle budding-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0033149-&&-FFAT motif binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:VAPB			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	VAPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAPB	0.40842986	0.06664198	76	4	FALSE	VAPB	VAPB	112.7567568	0	75	0	0.75859986	FALSE	1	VAPB	389416	0.032673
789874	taxon:9606	2.25492359	1.66E-04	174460	1902	DnaJ heat shock protein family (Hsp40) member A2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009408-&&-response to heat-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0042026-&&-protein refolding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DNAJA2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA2	0.44347401	0.17333333	76	4	FALSE	DNAJA2	DNAJA2	245.9473684	0	76	0	0.79084607	FALSE	0	DNAJA2	425278	0.05261469
789893	taxon:9606	2.38333071	1.76E-04	174414	1902	phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase	gene	biological_process-&-1&-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0009113-&&-purine nucleobase biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004638-&&-phosphoribosylaminoimidazole carboxylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004639-&&-phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	G:9606:PAICS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	PAICS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAICS	0.41958088	0.09218808	76	4	FALSE	PAICS	PAICS	177.9864865	0	75	0	0.76944488	FALSE	1	PAICS	352312	0.04604877
790032	taxon:9606	2.36221837	1.16E-04	174055	1902	cleavage and polyadenylation specific factor 6	gene	biological_process-&-1&-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006397-&&-mRNA processing-%%-GO:0051262-&&-protein tetramerization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0042382-&&-paraspeckles-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CPSF6			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CPSF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPSF6	0.42333089	0.15719298	76	4	FALSE	CPSF6	CPSF6	206.1842105	0	76	0	0.7729636	FALSE	0	CPSF6	268972	0.05156855
790130	taxon:9606	2.43532378	1.70E-04	173800	1902	RALY heterogeneous nuclear ribonucleoprotein	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:RALY				RALY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RALY	0.41062302	0.24947368	76	4	FALSE	RALY	RALY	254	0	76	0	0.76077937	FALSE	0	RALY	352588	0.07169604
790575	taxon:9606	2.33307074	1.29E-04	172094	1902	staphylococcal nuclease and tudor domain containing 1	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0097433-&&-dense body-%%-GO:0016442-&&-RISC complex|molecular_function-&-1&-GO:0004518-&&-nuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0003723-&&-RNA binding	G:9606:SND1			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	SND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SND1	0.42861967	0.26280702	76	4	FALSE	SND1	SND1	255.6973684	0	76	0	0.77782154	FALSE	0	SND1	289488	0.06123858
790999	taxon:9606	2.67102568	3.03E-04	170459	1902	protein arginine methyltransferase 6	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0034970-&&-histone H3-R2 methylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016049-&&-cell growth-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0090398-&&-cellular senescence-%%-GO:0016571-&&-histone methylation-%%-GO:0043985-&&-histone H4-R3 methylation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0042054-&&-histone methyltransferase activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0070611-&&-histone methyltransferase activity (H3-R2 specific)-%%-GO:0042393-&&-histone binding-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0070612-&&-histone methyltransferase activity (H2A-R3 specific)-%%-GO:0035241-&&-protein-arginine omega-N monomethyltransferase activity	G:9606:PRMT6				PRMT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT6	0.37438801	0.01298246	76	4	FALSE	PRMT6	PRMT6	90.52631579	0	76	0	0.72149572	FALSE	0	PRMT6	434612	0.04341788
791160	taxon:9606	2.42996691	4.33E-04	169857	1902	NPL4 homolog, ubiquitin recognition factor	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0007030-&&-Golgi organization-%%-GO:0070987-&&-error-free translesion synthesis|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036501-&&-UFD1-NPL4 complex-%%-GO:0042175-&&-nuclear outer membrane-endoplasmic reticulum membrane network-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NPLOC4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	NPLOC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPLOC4	0.41152824	0.10175439	76	4	FALSE	NPLOC4	NPLOC4	130.75	0	76	0	0.76167218	FALSE	0	NPLOC4	556278	0.03661359
791706	taxon:9606	2.62691035	2.75E-04	167284	1902	dystrobrevin binding protein 1	gene	biological_process-&-1&-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0032438-&&-melanosome organization-%%-GO:0001956-&&-positive regulation of neurotransmitter secretion-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0007596-&&-blood coagulation-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0031175-&&-neuron projection development-%%-GO:0043506-&&-regulation of JUN kinase activity-%%-GO:0060155-&&-platelet dense granule organization-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport|cellular_component-&-1&-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0030424-&&-axon-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0016528-&&-sarcoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0042383-&&-sarcolemma-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DTNBP1				DTNBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTNBP1	0.38067534	0.03776379	76	4	FALSE	DTNBP1	DTNBP1	58.55405405	0	75	0	0.72884827	FALSE	1	DTNBP1	248062	0.02473563
792243	taxon:9606	2.46919805	1.61E-04	182357	1902	ATPase H+ transporting V1 subunit A	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0006810-&&-transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016469-&&-proton-transporting two-sector ATPase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V1A			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1A	0.40498979	0.11699371	76	4	FALSE	ATP6V1A	ATP6V1A	135.527027	0	75	0	0.75513366	FALSE	1	ATP6V1A	269372	0.04056886
792416	taxon:9606	2.41562943	2.68E-04	182058	1902	CSK, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0042997-&&-negative regulation of Golgi to plasma membrane protein transport-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0034332-&&-adherens junction organization-%%-GO:0030154-&&-cell differentiation-%%-GO:0060368-&&-regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0010989-&&-negative regulation of low-density lipoprotein particle clearance-%%-GO:0007417-&&-central nervous system development-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007420-&&-brain development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0045121-&&-membrane raft-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:CSK			KEGG-&-1&-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	CSK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSK	0.41397078	0.12884117	76	4	FALSE	CSK	CSK	134.1351351	0	75	0	0.76406176	FALSE	1	CSK	362498	0.03673559
792439	taxon:9606	2.38742713	3.62E-04	182020	1902	C-terminal binding protein 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0048386-&&-positive regulation of retinoic acid receptor signaling pathway-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019079-&&-viral genome replication-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005634-&&-nucleus-%%-GO:0097470-&&-ribbon synapse-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0016616-&&-oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0051287-&&-NAD binding	G:9606:CTBP2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	CTBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTBP2	0.41886095	0.05405405	76	4	FALSE	CTBP2	CTBP2	122.0135135	0	75	0	0.76876214	FALSE	1	CTBP2	454664	0.03187676
792798	taxon:9606	2.29021585	1.02E-04	181355	1902	eukaryotic translation initiation factor 4A1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006413-&&-translational initiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004386-&&-helicase activity	G:9606:EIF4A1			KEGG-&-1&-hsa03013-&&-RNA transport	EIF4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A1	0.43664007	0.22596491	76	4	FALSE	EIF4A1	EIF4A1	273.631579	0	76	0	0.78496402	FALSE	0	EIF4A1	284760	0.06151789
787126	taxon:9606	2.34394202	2.18E-04	163633	1902	angiomotin	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0034613-&&-cellular protein localization-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0040019-&&-positive regulation of embryonic development-%%-GO:0035329-&&-hippo signaling-%%-GO:0042074-&&-cell migration involved in gastrulation-%%-GO:0003365-&&-establishment of cell polarity involved in ameboidal cell migration-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0034260-&&-negative regulation of GTPase activity|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0001726-&&-ruffle-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043532-&&-angiostatin binding	G:9606:AMOT			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction	AMOT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMOT	0.42663171	0.08751903	75	4	FALSE	AMOT	AMOT	158.4109589	0	74	0	0.77600966	FALSE	1	AMOT	373878	0.03858308
788125	taxon:9606	2.44729794	3.57E-04	178200	1902	protein tyrosine phosphatase, receptor type J	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0060242-&&-contact inhibition-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0009986-&&-cell surface-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0070097-&&-delta-catenin binding-%%-GO:0045295-&&-gamma-catenin binding	G:9606:PTPRJ			KEGG-&-1&-hsa04520-&&-Adherens junction	PTPRJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRJ	0.40861392	0.0825723	75	4	FALSE	PTPRJ	PTPRJ	116.3287671	0	74	0	0.75878368	FALSE	1	PTPRJ	413646	0.033566
788223	taxon:9606	2.40003151	9.72E-05	178055	1902	replication factor C subunit 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0003689-&&-DNA clamp loader activity	G:9606:RFC1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC1	0.4166612	0.20243531	75	4	FALSE	RFC1	RFC1	217.1232877	0	74	0	0.76666141	FALSE	1	RFC1	254342	0.0576886
788598	taxon:9606	2.52796597	5.94E-04	177371	1902	elongin B	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0030891-&&-VCB complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070449-&&-elongin complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:ELOB			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	ELOB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELOB	0.39557495	0.08900901	75	4	FALSE	ELOB	ELOB	109.3866667	0	75	0	0.74533901	FALSE	0	ELOB	1186544	0.03678439
789156	taxon:9606	2.45391524	1.42E-04	176087	1902	ASH2 like histone lysine methyltransferase complex subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0043627-&&-response to estrogen-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0048188-&&-Set1C/COMPASS complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990188-&&-euchromatin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:ASH2L			KEGG-&-1&-hsa04934-&&-Cushing syndrome	ASH2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASH2L	0.40751204	0.17922374	75	4	FALSE	ASH2L	ASH2L	172.109589	0	74	0	0.75768079	FALSE	1	ASH2L	299126	0.04992231
789397	taxon:9606	2.40775169	2.14E-04	175569	1902	serine and arginine rich splicing factor 11	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF11				SRSF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF11	0.41532522	0.21693694	75	4	FALSE	SRSF11	SRSF11	176.5066667	0	75	0	0.76537472	FALSE	0	SRSF11	350302	0.04757233
790025	taxon:9606	2.50764141	2.71E-04	174070	1902	destrin, actin depolymerizing factor	gene	biological_process-&-1&-GO:0030836-&&-positive regulation of actin filament depolymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0030043-&&-actin filament fragmentation-%%-GO:0030042-&&-actin filament depolymerization-%%-GO:0051014-&&-actin filament severing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:DSTN				DSTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSTN	0.3987811	0.0781982	75	4	FALSE	DSTN	DSTN	112.16	0	75	0	0.74872643	FALSE	0	DSTN	368040	0.03648003
790385	taxon:9606	2.41925319	2.56E-04	173152	1902	CD2 associated protein	gene	biological_process-&-1&-GO:0016050-&&-vesicle organization-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0051301-&&-cell division-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0032911-&&-negative regulation of transforming growth factor beta1 production-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0048259-&&-regulation of receptor-mediated endocytosis-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0001726-&&-ruffle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0031941-&&-filamentous actin|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005172-&&-vascular endothelial growth factor receptor binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:CD2AP			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	CD2AP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD2AP	0.4133507	0.10312024	75	4	FALSE	CD2AP	CD2AP	133.4383562	0	74	0	0.7634578	FALSE	1	CD2AP	348036	0.03674358
790516	taxon:9606	2.5341106	1.86E-04	172647	1902	TERF1 interacting nuclear factor 2	gene	biological_process-&-1&-GO:0034502-&&-protein localization to chromosome-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0010836-&&-negative regulation of protein ADP-ribosylation-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0016233-&&-telomere capping-%%-GO:0051974-&&-negative regulation of telomerase activity-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0032202-&&-telomere assembly|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0016604-&&-nuclear body-%%-GO:0010370-&&-perinucleolar chromocenter-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070187-&&-shelterin complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0010521-&&-telomerase inhibitor activity	G:9606:TINF2				TINF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TINF2	0.39461577	0.06773212	75	4	FALSE	TINF2	TINF2	94.69863014	0	74	0	0.7443149	FALSE	1	TINF2	239012	0.03240118
791156	taxon:9606	2.42807626	1.22E-04	169865	1902	ring finger protein 126	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0071629-&&-ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF126				RNF126	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF126	0.41184868	0.0890411	75	4	FALSE	RNF126	RNF126	139.1506849	0	74	0	0.76198729	FALSE	1	RNF126	220328	0.03883893
792555	taxon:9606	2.49724279	1.61E-04	181817	1902	runt related transcription factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001503-&&-ossification-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0030854-&&-positive regulation of granulocyte differentiation-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0002062-&&-chondrocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding-%%-GO:0000975-&&-regulatory region DNA binding	G:9606:RUNX1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04530-&&-Tight junction-%%-hsa05220-&&-Chronic myeloid leukemia	RUNX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX1	0.40044164	0.15715373	75	4	FALSE	RUNX1	RUNX1	132.9315069	0	74	0	0.75045953	FALSE	1	RUNX1	253282	0.04194773
787133	taxon:9606	2.33874271	1.75E-04	180010	1902	inosine monophosphate dehydrogenase 2	gene	biological_process-&-1&-GO:0006177-&&-GMP biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0046651-&&-lymphocyte proliferation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006183-&&-GTP biosynthetic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003938-&&-IMP dehydrogenase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0046872-&&-metal ion binding	G:9606:IMPDH2			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	IMPDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IMPDH2	0.42758017	0.10289515	74	4	FALSE	IMPDH2	IMPDH2	224.9166667	0	73	0	0.77687621	FALSE	1	IMPDH2	349182	0.05433046
787607	taxon:9606	2.35402552	2.91E-04	179111	1902	NFKB inhibitor beta	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFKBIB			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NFKBIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIB	0.42480423	0.12558685	74	4	FALSE	NFKBIB	NFKBIB	168.2916667	0	73	0	0.77432908	FALSE	1	NFKBIB	386896	0.04163916
787648	taxon:9606	2.37781629	3.71E-04	179019	1902	N-ethylmaleimide sensitive factor, vesicle fusing ATPase	gene	biological_process-&-1&-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006813-&&-potassium ion transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0045026-&&-plasma membrane fusion-%%-GO:0006887-&&-exocytosis-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0035494-&&-SNARE complex disassembly|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043198-&&-dendritic shaft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005829-&&-cytosol-%%-GO:0005795-&&-Golgi stack-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0046872-&&-metal ion binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005524-&&-ATP binding	G:9606:NSF			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04727-&&-GABAergic synapse-%%-hsa04721-&&-Synaptic vesicle cycle	NSF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSF	0.42055394	0.07550861	74	4	FALSE	NSF	NSF	161.1666667	0	73	0	0.77036395	FALSE	1	NSF	544778	0.04133174
789124	taxon:9606	2.44651016	9.84E-05	159768	1902	small ubiquitin-like modifier 4	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031386-&&-protein tag	G:9606:SUMO4			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO4	0.40874549	0.08626435	74	4	FALSE	SUMO4	SUMO4	134.7837838	0	74	0	0.75891497	FALSE	0	SUMO4	184796	0.03893579
789281	taxon:9606	2.50953206	2.57E-04	175834	1902	cytosolic iron-sulfur assembly component 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016226-&&-iron-sulfur cluster assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007059-&&-chromosome segregation|cellular_component-&-1&-GO:0071817-&&-MMXD complex-%%-GO:0097361-&&-CIA complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CIAO1				CIAO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIAO1	0.39848066	0.03146983	74	4	FALSE	CIAO1	CIAO1	85.95945946	0	74	0	0.74841132	FALSE	0	CIAO1	291724	0.02798913
789315	taxon:9606	2.49960611	1.62E-04	175767	1902	autophagy related 5	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0009620-&&-response to fungus-%%-GO:0016236-&&-macroautophagy-%%-GO:0043687-&&-post-translational protein modification-%%-GO:0060047-&&-heart contraction-%%-GO:0042311-&&-vasodilation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0070257-&&-positive regulation of mucus secretion-%%-GO:0044804-&&-nucleophagy-%%-GO:0071500-&&-cellular response to nitrosative stress-%%-GO:0006914-&&-autophagy-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0019883-&&-antigen processing and presentation of endogenous antigen-%%-GO:0035973-&&-aggrephagy-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0039689-&&-negative stranded viral RNA replication-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0000422-&&-mitophagy-%%-GO:0002739-&&-regulation of cytokine secretion involved in immune response-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0048840-&&-otolith development-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0042493-&&-response to drug-%%-GO:0061739-&&-protein lipidation involved in autophagosome assembly-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:2000619-&&-negative regulation of histone H4-K16 acetylation-%%-GO:0001974-&&-blood vessel remodeling|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0005776-&&-autophagosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005829-&&-cytosol-%%-GO:0034274-&&-Atg12-Atg5-Atg16 complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0030670-&&-phagocytic vesicle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019776-&&-Atg8 ligase activity	G:9606:ATG5			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05131-&&-Shigellosis-%%-hsa04136-&&-Autophagy - other-%%-hsa04216-&&-Ferroptosis-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	ATG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG5	0.40006303	0.05203443	74	4	FALSE	ATG5	ATG5	102.5	0	73	0	0.75006565	FALSE	1	ATG5	237194	0.03283071
789537	taxon:9606	2.50968962	7.53E-05	175233	1902	histone deacetylase 9	gene	biological_process-&-1&-GO:0070933-&&-histone H4 deacetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051153-&&-regulation of striated muscle cell differentiation-%%-GO:0007507-&&-heart development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030183-&&-B cell differentiation-%%-GO:0048742-&&-regulation of skeletal muscle fiber development-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis-%%-GO:0001975-&&-response to amphetamine-%%-GO:0016575-&&-histone deacetylation-%%-GO:0042113-&&-B cell activation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0003714-&&-transcription corepressor activity	G:9606:HDAC9			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC9	0.39845565	0.15453834	74	4	FALSE	HDAC9	HDAC9	162.8611111	0	73	0	0.74838506	FALSE	1	HDAC9	179944	0.05249302
789780	taxon:9606	2.32125414	3.84E-04	174693	1902	tyrosine kinase non receptor 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:2000369-&&-regulation of clathrin-dependent endocytosis-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0006897-&&-endocytosis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070436-&&-Grb2-EGFR complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:TNK2				TNK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNK2	0.4308016	0.09741784	74	4	FALSE	TNK2	TNK2	161.2361111	0	73	0	0.77979098	FALSE	1	TNK2	526626	0.0379281
789928	taxon:9606	2.35812195	1.54E-04	174333	1902	ubiquitin specific peptidase 39	gene	biological_process-&-1&-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:USP39			KEGG-&-1&-hsa03040-&&-Spliceosome	USP39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP39	0.42406628	0.17882266	74	4	FALSE	USP39	USP39	184.3513514	0	74	0	0.77364634	FALSE	0	USP39	277636	0.04595943
790551	taxon:9606	2.37765874	6.78E-05	172256	1902	G protein nucleolar 3	gene	biological_process-&-1&-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:1904816-&&-positive regulation of protein localization to chromosome, telomeric region-%%-GO:0008283-&&-cell proliferation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005615-&&-extracellular space-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:GNL3			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GNL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNL3	0.4205818	0.37245465	74	4	FALSE	GNL3	GNL3	249.3918919	0	74	0	0.77039021	FALSE	0	GNL3	188394	0.06381228
790623	taxon:9606	2.48526863	1.69E-04	171725	1902	protein phosphatase methylesterase 1	gene	biological_process-&-1&-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006482-&&-protein demethylation|molecular_function-&-1&-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0051722-&&-protein C-terminal methylesterase activity	G:9606:PPME1				PPME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPME1	0.40237099	0.10093897	74	4	FALSE	PPME1	PPME1	121.2083333	0	73	0	0.75245523	FALSE	1	PPME1	247690	0.03745921
790817	taxon:9606	2.50968962	1.27E-04	171123	1902	WD repeat containing, antisense to TP73	gene	biological_process-&-1&-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0030030-&&-cell projection organization-%%-GO:0090307-&&-mitotic spindle assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005814-&&-centriole-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WRAP73				WRAP73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WRAP73	0.39845565	0.06885759	74	4	FALSE	WRAP73	WRAP73	108.0833333	0	73	0	0.74838506	FALSE	1	WRAP73	206308	0.03501495
791007	taxon:9606	2.51347093	9.84E-05	170426	1902	methyl-CpG binding domain protein 3	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0007420-&&-brain development-%%-GO:0048568-&&-embryonic organ development-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0009888-&&-tissue development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007568-&&-aging-%%-GO:0016573-&&-histone acetylation-%%-GO:0032355-&&-response to estradiol-%%-GO:0016575-&&-histone deacetylation-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0006346-&&-methylation-dependent chromatin silencing|cellular_component-&-1&-GO:0016581-&&-NuRD complex-%%-GO:0000792-&&-heterochromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:MBD3				MBD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBD3	0.3978562	0.22456964	74	4	FALSE	MBD3	MBD3	175.6666667	0	73	0	0.74775484	FALSE	1	MBD3	229540	0.05686846
791146	taxon:9606	2.44572239	1.08E-04	169890	1902	autophagy and beclin 1 regulator 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:0016236-&&-macroautophagy-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0021915-&&-neural tube development-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005930-&&-axoneme-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:AMBRA1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04137-&&-Mitophagy - animal	AMBRA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMBRA1	0.40887715	0.20325805	74	4	FALSE	AMBRA1	AMBRA1	160.9054054	0	74	0	0.75904627	FALSE	0	AMBRA1	210916	0.04626931
791237	taxon:9606	2.41925319	1.53E-04	169566	1902	ring finger protein 20	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:0031062-&&-positive regulation of histone methylation-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0033503-&&-HULC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0042393-&&-histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:RNF20				RNF20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF20	0.4133507	0.10289515	74	4	FALSE	RNF20	RNF20	168.7361111	0	73	0	0.7634578	FALSE	1	RNF20	295378	0.04625187
791368	taxon:9606	2.46147786	1.49E-04	168946	1902	ubiquitin specific peptidase 37	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0035871-&&-protein K11-linked deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP37				USP37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP37	0.40626	0.1185446	74	4	FALSE	USP37	USP37	148.1527778	0	73	0	0.75642036	FALSE	1	USP37	235606	0.04362216
792132	taxon:9606	2.35985505	4.24E-04	182543	1902	actin, alpha 2, smooth muscle, aorta	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006936-&&-muscle contraction-%%-GO:0072144-&&-glomerular mesangial cell development-%%-GO:0009615-&&-response to virus-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0090131-&&-mesenchyme migration-%%-GO:0014829-&&-vascular smooth muscle contraction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0030027-&&-lamellipodium-%%-GO:0030485-&&-smooth muscle contractile fiber-%%-GO:0043234-&&-protein complex-%%-GO:0030175-&&-filopodium-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ACTA2			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway	ACTA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTA2	0.42375484	0.12217697	74	4	FALSE	ACTA2	ACTA2	192.1351351	0	74	0	0.77335749	FALSE	0	ACTA2	627226	0.04796403
792672	taxon:9606	2.31904837	1.12E-04	181583	1902	aspartyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006412-&&-translation-%%-GO:0006422-&&-aspartyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004046-&&-aminoacylase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004815-&&-aspartate-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:DARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	DARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DARS	0.43121136	0.23102555	74	4	FALSE	DARS	DARS	234.1081081	0	74	0	0.78015861	FALSE	0	DARS	289434	0.0549034
793068	taxon:9606	2.40176461	2.21E-04	180808	1902	general transcription factor IIF subunit 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009615-&&-response to virus-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005674-&&-transcription factor TFIIF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019211-&&-phosphatase activator activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0003723-&&-RNA binding	G:9606:GTF2F1			KEGG-&-1&-hsa03022-&&-Basal transcription factors	GTF2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2F1	0.41636054	0.11810441	74	4	FALSE	GTF2F1	GTF2F1	144.2162162	0	74	0	0.76637256	FALSE	0	GTF2F1	342404	0.03829008
787153	taxon:9606	2.50338743	2.79E-04	179975	1902	LIM domain only 2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0048037-&&-cofactor binding	G:9606:LMO2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	LMO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMO2	0.39945875	0.05593561	73	4	FALSE	LMO2	LMO2	98.70422535	0	72	0	0.74943543	FALSE	1	LMO2	343336	0.03176274
787210	taxon:9606	2.31936348	1.69E-04	179863	1902	methionyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006431-&&-methionyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004825-&&-methionine-tRNA ligase activity-%%-GO:0000049-&&-tRNA binding	G:9606:MARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa00450-&&-Selenocompound metabolism	MARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARS	0.43115277	0.17770167	73	4	FALSE	MARS	MARS	230.1369863	0	73	0	0.78010609	FALSE	0	MARS	323776	0.05395924
787293	taxon:9606	2.52150622	8.19E-04	179720	1902	kinase insert domain receptor	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0016032-&&-viral process-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0001570-&&-vasculogenesis-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0003158-&&-endothelium development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030054-&&-cell junction-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0097443-&&-sorting endosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity	G:9606:KDR	KDR	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	KDR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDR	0.39658835	0.0889336	73	4	FALSE	KDR	KDR	105.6197183	0	72	0	0.74641563	FALSE	1	KDR	1014144	0.03521362
787480	taxon:9606	2.57239641	2.20E-04	179353	1902	myeloid leukemia factor 1	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:MLF1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	MLF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLF1	0.38874257	0.06197183	73	4	FALSE	MLF1	MLF1	82.11267606	0	72	0	0.73793393	FALSE	1	MLF1	244186	0.03052867
787887	taxon:9606	2.56861509	4.92E-05	178658	1902	proteasome subunit beta 7	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB7			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB7	0.38931485	0.42414487	73	4	FALSE	PSMB7	PSMB7	120.8309859	0	72	0	0.73856415	FALSE	1	PSMB7	108262	0.04450497
788019	taxon:9606	2.3415787	1.71E-04	178388	1902	phosphofructokinase, platelet	gene	biological_process-&-1&-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003872-&&-6-phosphofructokinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0045296-&&-cadherin binding	G:9606:PFKP			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa00052-&&-Galactose metabolism-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa00030-&&-Pentose phosphate pathway	PFKP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKP	0.42706231	0.11111111	73	4	FALSE	PFKP	PFKP	215.739726	0	73	0	0.77640355	FALSE	0	PFKP	358008	0.05235071
788098	taxon:9606	2.45013392	1.90E-04	178246	1902	progesterone receptor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0051117-&&-ATPase binding	G:9606:PGR	PGR	TRUE	KEGG-&-1&-hsa04114-&&-Oocyte meiosis-%%-hsa05224-&&-Breast cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04915-&&-Estrogen signaling pathway	PGR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGR	0.40814096	0.1110664	73	4	FALSE	PGR	PGR	136.9295775	0	72	0	0.75831101	FALSE	1	PGR	298580	0.03969716
788208	taxon:9606	2.46730739	1.72E-04	178078	1902	reticulocalbin 1	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0043010-&&-camera-type eye development|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:RCN1				RCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCN1	0.40530013	0.08143075	73	4	FALSE	RCN1	RCN1	138.2465753	0	73	0	0.75544877	FALSE	0	RCN1	304412	0.04139137
788442	taxon:9606	2.49472192	2.94E-04	177670	1902	SKI like proto-oncogene	gene	biological_process-&-1&-GO:0034097-&&-response to cytokine-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0048666-&&-neuron development-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0001825-&&-blastocyst formation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0002260-&&-lymphocyte homeostasis|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046332-&&-SMAD binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:SKIL			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	SKIL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKIL	0.40084628	0.08088531	73	4	FALSE	SKIL	SKIL	112.5492958	0	72	0	0.75087968	FALSE	1	SKIL	335114	0.03559036
788612	taxon:9606	2.46525918	2.18E-04	177308	1902	dynein light chain Tctex-type 1	gene	biological_process-&-1&-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0019060-&&-intracellular transport of viral protein in host cell-%%-GO:0075521-&&-microtubule-dependent intracellular transport of viral material towards nucleus-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051493-&&-regulation of cytoskeleton organization|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005819-&&-spindle-%%-GO:0043657-&&-host cell-%%-GO:0099503-&&-secretory vesicle|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:DYNLT1				DYNLT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNLT1	0.40563686	0.03501006	73	4	FALSE	DYNLT1	DYNLT1	96.16901408	0	72	0	0.75579014	FALSE	1	DYNLT1	279628	0.0286955
788824	taxon:9606	2.49346148	1.19E-04	176805	1902	ubiquitin conjugating enzyme E2 V1	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006301-&&-postreplication repair-%%-GO:0030154-&&-cell differentiation-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0007254-&&-JNK cascade-%%-GO:0000187-&&-activation of MAPK activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031371-&&-ubiquitin conjugating enzyme complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0035370-&&-UBC13-UEV1A complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:UBE2V1				UBE2V1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2V1	0.40104891	0.15694165	73	4	FALSE	UBE2V1	UBE2V1	135.0704225	0	72	0	0.75108975	FALSE	1	UBE2V1	250836	0.04242162
788840	taxon:9606	2.41547188	1.93E-04	176772	1902	ubiquitin specific peptidase 4	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031685-&&-adenosine receptor binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP4				USP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP4	0.41399778	0.07806841	73	4	FALSE	USP4	USP4	140.7183099	0	72	0	0.76408802	FALSE	1	USP4	304286	0.03842454
789058	taxon:9606	2.41137545	9.82E-05	176268	1902	tripartite motif containing 24	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0070562-&&-regulation of vitamin D receptor signaling pathway-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030163-&&-protein catabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0005634-&&-nucleus-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0034056-&&-estrogen response element binding	G:9606:TRIM24				TRIM24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM24	0.41470108	0.24869215	73	4	FALSE	TRIM24	TRIM24	230.4225352	0	72	0	0.76477076	FALSE	1	TRIM24	263934	0.06207124
789259	taxon:9606	2.3018749	2.10E-04	175887	1902	eukaryotic translation initiation factor 3 subunit F	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:EIF3F			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3F	0.43442847	0.16438356	73	4	FALSE	EIF3F	EIF3F	205.890411	0	73	0	0.78302085	FALSE	0	EIF3F	372450	0.04713119
789274	taxon:9606	2.42161651	1.16E-04	175846	1902	TNFRSF1A associated via death domain	gene	biological_process-&-1&-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0051798-&&-positive regulation of hair follicle development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0070513-&&-death domain binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0060090-&&-binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding	G:9606:TRADD			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	TRADD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRADD	0.4129473	0.15050302	73	4	FALSE	TRADD	TRADD	146.7042254	0	72	0	0.76306391	FALSE	1	TRADD	232898	0.04055185
789762	taxon:9606	2.48054199	3.58E-04	174741	1902	optineurin	gene	biological_process-&-1&-GO:0061734-&&-parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization-%%-GO:0016236-&&-macroautophagy-%%-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0000042-&&-protein targeting to Golgi-%%-GO:0008219-&&-cell death-%%-GO:0001920-&&-negative regulation of receptor recycling-%%-GO:0007030-&&-Golgi organization-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090161-&&-Golgi ribbon formation-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:1904417-&&-positive regulation of xenophagy|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0042802-&&-identical protein binding	G:9606:OPTN			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	OPTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPTN	0.4031377	0.07887324	73	4	FALSE	OPTN	OPTN	116.6478873	0	72	0	0.753243	FALSE	1	OPTN	376174	0.03580263
790033	taxon:9606	2.42807626	2.63E-04	174049	1902	WW domain containing E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0051224-&&-negative regulation of protein transport-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding	G:9606:WWP2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	WWP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWP2	0.41184868	0.06358149	73	4	FALSE	WWP2	WWP2	133.4788732	0	72	0	0.76198729	FALSE	1	WWP2	364650	0.03733656
790427	taxon:9606	2.46636206	2.32E-04	173016	1902	DAZ associated protein 1	gene	biological_process-&-1&-GO:0001893-&&-maternal placenta development-%%-GO:0008283-&&-cell proliferation-%%-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding	G:9606:DAZAP1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	DAZAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAZAP1	0.40545547	0.1651446	73	4	FALSE	DAZAP1	DAZAP1	185.8630137	0	73	0	0.75560632	FALSE	0	DAZAP1	394248	0.05559357
790748	taxon:9606	2.35591618	1.81E-04	171338	1902	COP9 signalosome subunit 4	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0019784-&&-NEDD8-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:COPS4				COPS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS4	0.42446332	0.21609658	73	4	FALSE	COPS4	COPS4	184.2394366	0	72	0	0.77401397	FALSE	1	COPS4	325078	0.04560465
790821	taxon:9606	2.40932724	2.54E-04	171093	1902	gem nuclear organelle associated protein 4	gene	biological_process-&-1&-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006364-&&-rRNA processing-%%-GO:0051170-&&-nuclear import|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GEMIN4			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN4	0.41505362	0.11750503	73	4	FALSE	GEMIN4	GEMIN4	165.056338	0	72	0	0.76511213	FALSE	1	GEMIN4	390692	0.04448259
790989	taxon:9606	2.51441626	1.22E-04	170483	1902	HAUS augmin like complex subunit 2	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005876-&&-spindle microtubule-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:HAUS2				HAUS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS2	0.39770662	0.09208524	73	4	FALSE	HAUS2	HAUS2	119.6164384	0	73	0	0.74759729	FALSE	0	HAUS2	206164	0.03905519
791265	taxon:9606	2.52954152	2.50E-04	169443	1902	zinc finger protein 512B	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF512B				ZNF512B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF512B	0.39532856	0.08980213	73	4	FALSE	ZNF512B	ZNF512B	142.9726027	0	73	0	0.74507641	FALSE	0	ZNF512B	396892	0.048471
791979	taxon:9606	2.44981881	1.57E-04	182776	1902	baculoviral IAP repeat containing 3	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0039535-&&-regulation of RIG-I signaling pathway-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070424-&&-regulation of nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0045088-&&-regulation of innate immune response|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:BIRC3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	BIRC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC3	0.40819345	0.1778672	73	4	FALSE	BIRC3	BIRC3	135.4788732	0	72	0	0.75836353	FALSE	1	BIRC3	256626	0.03931482
792077	taxon:9606	2.45895699	3.72E-04	182652	1902	chloride nucleotide-sensitive channel 1A	gene	biological_process-&-1&-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006884-&&-cell volume homeostasis-%%-GO:0006821-&&-chloride transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:CLNS1A			KEGG-&-1&-hsa03013-&&-RNA transport	CLNS1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLNS1A	0.40667649	0.09056317	73	4	FALSE	CLNS1A	CLNS1A	136.8630137	0	73	0	0.7568405	FALSE	0	CLNS1A	508742	0.04044763
792120	taxon:9606	2.37718607	1.62E-04	182574	1902	coatomer protein complex subunit alpha	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0030157-&&-pancreatic juice secretion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005198-&&-structural molecule activity	G:9606:COPA	COPA	TRUE		COPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPA	0.42066543	0.14366197	73	4	FALSE	COPA	COPA	220.028169	0	72	0	0.77046899	FALSE	1	COPA	347286	0.05631639
792401	taxon:9606	2.41373877	6.74E-04	182090	1902	crystallin alpha B	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:1905907-&&-negative regulation of amyloid fibril formation-%%-GO:0010941-&&-regulation of cell death-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006936-&&-muscle contraction-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032387-&&-negative regulation of intracellular transport-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031109-&&-microtubule polymerization or depolymerization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006457-&&-protein folding-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0071480-&&-cellular response to gamma radiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0031674-&&-I band-%%-GO:0032432-&&-actin filament bundle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097512-&&-cardiac myofibril-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0097060-&&-synaptic membrane-%%-GO:0031430-&&-M band-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:CRYAB			KEGG-&-1&-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CRYAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRYAB	0.41429504	0.06036217	73	4	FALSE	CRYAB	CRYAB	108.3098592	0	72	0	0.76437687	FALSE	1	CRYAB	586480	0.02955053
792820	taxon:9606	2.44272885	1.97E-04	181309	1902	enolase 2	gene	biological_process-&-1&-GO:0006094-&&-gluconeogenesis-%%-GO:0061621-&&-canonical glycolysis|cellular_component-&-1&-GO:0043204-&&-perikaryon-%%-GO:0000015-&&-phosphopyruvate hydratase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0004634-&&-phosphopyruvate hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:ENO2	ENO2	TRUE	KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa04066-&&-HIF-1 signaling pathway	ENO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENO2	0.40937822	0.16901408	73	4	FALSE	ENO2	ENO2	146.0422535	0	72	0	0.75954519	FALSE	1	ENO2	316012	0.04184972
792838	taxon:9606	2.48968016	2.94E-04	164903	1902	charged multivesicular body protein 4B	gene	biological_process-&-1&-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0016236-&&-macroautophagy-%%-GO:0090611-&&-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0050792-&&-regulation of viral process-%%-GO:0019058-&&-viral life cycle-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0006997-&&-nucleus organization-%%-GO:0007034-&&-vacuolar transport-%%-GO:0006914-&&-autophagy-%%-GO:0006620-&&-posttranslational protein targeting to membrane-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0016197-&&-endosomal transport-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0010458-&&-exit from mitosis-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0036438-&&-maintenance of lens transparency-%%-GO:0046755-&&-viral budding-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0090148-&&-membrane fission|cellular_component-&-1&-GO:0030117-&&-membrane coat-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0000815-&&-ESCRT III complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0030496-&&-midbody-%%-GO:0031902-&&-late endosome membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:CHMP4B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	CHMP4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHMP4B	0.40165802	0.07645875	73	4	FALSE	CHMP4B	CHMP4B	120.028169	0	72	0	0.75171997	FALSE	1	CHMP4B	366196	0.03745019
787415	taxon:9606	2.46856783	2.03E-04	163090	1902	taxilin alpha	gene	biological_process-&-1&-GO:0042113-&&-B cell activation-%%-GO:0006887-&&-exocytosis-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0030372-&&-high molecular weight B cell growth factor receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TXLNA				TXLNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXLNA	0.40509318	0.1010352	72	4	FALSE	TXLNA	TXLNA	121.9857143	0	71	0	0.7552387	FALSE	1	TXLNA	298552	0.03646617
787576	taxon:9606	2.41326611	1.55E-04	179148	1902	septin 2	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0031175-&&-neuron projection development-%%-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0031105-&&-septin complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0005930-&&-axoneme-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005938-&&-cell cortex-%%-GO:0000145-&&-exocyst-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0097227-&&-sperm annulus-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0060170-&&-ciliary membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005525-&&-GTP binding	G:9606:SEPT2			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT2	0.41437618	0.13223787	72	4	FALSE	SEPT2	SEPT2	162.4305556	0	72	0	0.76445565	FALSE	0	SEPT2	274930	0.04415896
787600	taxon:9606	2.40664881	2.77E-04	179119	1902	nuclear factor, erythroid 2 like 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:1903788-&&-positive regulation of glutathione biosynthetic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:1902037-&&-negative regulation of hematopoietic stem cell differentiation-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045995-&&-regulation of embryonic development-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1904753-&&-negative regulation of vascular associated smooth muscle cell migration-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0007568-&&-aging-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0036091-&&-positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005813-&&-centrosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:NFE2L2	NFE2L2	TRUE	KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	NFE2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFE2L2	0.41551555	0.10837246	72	4	FALSE	NFE2L2	NFE2L2	143.875	0	72	0	0.76555853	FALSE	0	NFE2L2	377938	0.03859516
787786	taxon:9606	2.30723176	2.94E-04	178794	1902	protein phosphatase 5 catalytic subunit	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0000165-&&-MAPK cascade-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043278-&&-response to morphine-%%-GO:0016576-&&-histone dephosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:2000324-&&-positive regulation of glucocorticoid receptor signaling pathway-%%-GO:1901215-&&-negative regulation of neuron death|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:1990635-&&-proximal dendrite-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0043531-&&-ADP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:PPP5C			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PPP5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP5C	0.43341983	0.11469979	72	4	FALSE	PPP5C	PPP5C	177.4857143	0	71	0	0.78212804	FALSE	1	PPP5C	403138	0.04085675
788073	taxon:9606	2.46179297	6.37E-05	178283	1902	ribosomal protein L29	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0007566-&&-embryo implantation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008201-&&-heparin binding-%%-GO:0045296-&&-cadherin binding	G:9606:RPL29			KEGG-&-1&-hsa03010-&&-Ribosome	RPL29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL29	0.406208	0.3943662	72	4	FALSE	RPL29	RPL29	242.3194444	0	72	0	0.75636784	FALSE	0	RPL29	177444	0.07171814
788107	taxon:9606	2.55538049	3.08E-04	178225	1902	pleiotrophin	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0014823-&&-response to activity-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0007507-&&-heart development-%%-GO:0021549-&&-cerebellum development-%%-GO:1904389-&&-rod bipolar cell differentiation-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0044849-&&-estrous cycle-%%-GO:0060221-&&-retinal rod cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030282-&&-bone mineralization-%%-GO:0007399-&&-nervous system development-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0021510-&&-spinal cord development-%%-GO:1904397-&&-negative regulation of neuromuscular junction development-%%-GO:1904373-&&-response to kainic acid-%%-GO:0001889-&&-liver development-%%-GO:0034644-&&-cellular response to UV-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:1904391-&&-response to ciliary neurotrophic factor-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0072201-&&-negative regulation of mesenchymal cell proliferation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0030324-&&-lung development-%%-GO:0032570-&&-response to progesterone-%%-GO:1904395-&&-positive regulation of skeletal muscle acetylcholine-gated channel clustering-%%-GO:0021794-&&-thalamus development-%%-GO:1990089-&&-response to nerve growth factor-%%-GO:0042493-&&-response to drug-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0007612-&&-learning-%%-GO:0045446-&&-endothelial cell differentiation-%%-GO:0045837-&&-negative regulation of membrane potential-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0032355-&&-response to estradiol-%%-GO:0071305-&&-cellular response to vitamin D-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005604-&&-basement membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0035374-&&-chondroitin sulfate binding-%%-GO:1904399-&&-heparan sulfate binding-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0035373-&&-chondroitin sulfate proteoglycan binding	G:9606:PTN				PTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTN	0.39133115	0.02939959	72	4	FALSE	PTN	PTN	84.97142857	0	71	0	0.74076992	FALSE	1	PTN	325272	0.03067958
788262	taxon:9606	2.37655585	1.68E-04	177976	1902	ribophorin II	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0007568-&&-aging-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity	G:9606:RPN2			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	RPN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPN2	0.42077698	0.14749609	72	4	FALSE	RPN2	RPN2	190.0277778	0	72	0	0.77057402	FALSE	0	RPN2	335786	0.04855964
788362	taxon:9606	2.39105089	2.73E-04	177806	1902	succinate dehydrogenase complex flavoprotein subunit A	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006121-&&-mitochondrial electron transport, succinate to ubiquinone-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0009061-&&-anaerobic respiration-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005749-&&-mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)-%%-GO:0045282-&&-plasma membrane succinate dehydrogenase complex|molecular_function-&-1&-GO:0008177-&&-succinate dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0000104-&&-succinate dehydrogenase activity	G:9606:SDHA			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05016-&&-Huntington disease	SDHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDHA	0.41822615	0.11776213	72	4	FALSE	SDHA	SDHA	189.75	0	72	0	0.76815818	FALSE	0	SDHA	404328	0.0497009
788714	taxon:9606	2.5090594	1.79E-04	177135	1902	tropomyosin 2 (beta)	gene	biological_process-&-1&-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction-%%-GO:0007015-&&-actin filament organization-%%-GO:0043462-&&-regulation of ATPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005884-&&-actin filament-%%-GO:0005862-&&-muscle thin filament tropomyosin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:TPM2	TPM2	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM2	0.39855573	0.11552795	72	4	FALSE	TPM2	TPM2	119.4714286	0	71	0	0.7484901	FALSE	1	TPM2	256340	0.03876954
788875	taxon:9606	2.4610052	3.45E-04	176715	1902	vitronectin	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0097421-&&-liver regeneration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0061302-&&-smooth muscle cell-matrix adhesion-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0006955-&&-immune response-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0051258-&&-protein polymerization-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0048709-&&-oligodendrocyte differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0071062-&&-alphav-beta3 integrin-vitronectin complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005604-&&-basement membrane-%%-GO:0048237-&&-rough endoplasmic reticulum lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0050840-&&-extracellular matrix binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005518-&&-collagen binding-%%-GO:0008201-&&-heparin binding-%%-GO:0030247-&&-polysaccharide binding	G:9606:VTN	VTN	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa05165-&&-Human papillomavirus infection	VTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VTN	0.40633803	0.1314554	72	4	FALSE	VTN	VTN	137.2083333	0	72	0	0.75649913	FALSE	0	VTN	417776	0.04079474
788877	taxon:9606	2.53111706	1.91E-04	176711	1902	Wiskott-Aldrich syndrome	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0008544-&&-epidermis development-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007596-&&-blood coagulation-%%-GO:2000601-&&-positive regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0006952-&&-defense response-%%-GO:0006955-&&-immune response-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0016197-&&-endosomal transport-%%-GO:0042110-&&-T cell activation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0002625-&&-regulation of T cell antigen processing and presentation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0019901-&&-protein kinase binding	G:9606:WAS			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	WAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WAS	0.39508248	0.08902692	72	4	FALSE	WAS	WAS	100.6857143	0	71	0	0.74481382	FALSE	1	WAS	263474	0.03433935
788882	taxon:9606	2.46730739	6.99E-05	176699	1902	nuclear receptor binding SET domain protein 2	gene	biological_process-&-1&-GO:2001032-&&-regulation of double-strand break repair via nonhomologous end joining-%%-GO:0010452-&&-histone H3-K36 methylation-%%-GO:0048298-&&-positive regulation of isotype switching to IgA isotypes-%%-GO:0034770-&&-histone H4-K20 methylation-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0060348-&&-bone development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0003290-&&-atrial septum secundum morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042799-&&-histone methyltransferase activity (H4-K20 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NSD2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa00310-&&-Lysine degradation	NSD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSD2	0.40530013	0.22939959	72	4	FALSE	NSD2	NSD2	220.2428571	0	71	0	0.75544877	FALSE	1	NSD2	190968	0.06561808
789035	taxon:9606	2.36080038	2.38E-04	176318	1902	phosphatidylinositol binding clathrin assembly protein	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:1902963-&&-negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0016197-&&-endosomal transport-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0031623-&&-receptor internalization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0097459-&&-iron ion import into cell-%%-GO:0007409-&&-axonogenesis-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0030097-&&-hemopoiesis-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0035459-&&-cargo loading into vesicle-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:1902959-&&-regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process-%%-GO:1902961-&&-positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0032050-&&-clathrin heavy chain binding-%%-GO:0005545-&&-1-phosphatidylinositol binding	G:9606:PICALM				PICALM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PICALM	0.42358516	0.17683881	72	4	FALSE	PICALM	PICALM	191.5277778	0	72	0	0.77319994	FALSE	0	PICALM	353436	0.04780483
789167	taxon:9606	2.39057823	3.59E-04	176062	1902	ubiquitin specific peptidase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0050821-&&-protein stabilization-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0048512-&&-circadian behavior-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0045475-&&-locomotor rhythm|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0046872-&&-metal ion binding	G:9606:USP2				USP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP2	0.41830884	0.07902973	72	4	FALSE	USP2	USP2	131.1805556	0	72	0	0.76823696	FALSE	0	USP2	421330	0.03436918
789173	taxon:9606	2.45470301	3.53E-05	176048	1902	histone cluster 1 H2A family member b	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AB	0.40738126	0.4194617	72	4	FALSE	HIST1H2AB	HIST1H2AB	260.4714286	0	71	0	0.7575495	FALSE	1	HIST1H2AB	141228	0.07578453
789689	taxon:9606	2.67181346	5.46E-04	174888	1902	cAMP responsive element binding protein 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:CREB3			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB3	0.37427763	0.02401656	72	4	FALSE	CREB3	CREB3	47.14285714	0	71	0	0.72136442	FALSE	1	CREB3	482756	0.02295693
789826	taxon:9606	2.44540728	2.87E-04	174552	1902	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone	gene	biological_process-&-1&-GO:0043947-&&-positive regulation by host of symbiont catalytic activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031647-&&-regulation of protein stability|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SUGT1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	SUGT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUGT1	0.40892984	0.06611894	72	4	FALSE	SUGT1	SUGT1	125.9166667	0	72	0	0.75909879	FALSE	0	SUGT1	383736	0.03602045
789946	taxon:9606	2.55853159	1.96E-04	174276	1902	NIMA related kinase 6	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0000910-&&-cytokinesis-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2000772-&&-regulation of cellular senescence|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019894-&&-kinesin binding	G:9606:NEK6				NEK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK6	0.39084919	0.03229814	72	4	FALSE	NEK6	NEK6	85.57142857	0	71	0	0.74024474	FALSE	1	NEK6	243830	0.03080808
790255	taxon:9606	2.40538837	1.08E-04	173496	1902	La ribonucleoprotein domain family member 1	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0072752-&&-cellular response to rapamycin-%%-GO:1990928-&&-response to amino acid starvation-%%-GO:0031929-&&-TOR signaling-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0031931-&&-TORC1 complex-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0031369-&&-translation initiation factor binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008190-&&-eukaryotic initiation factor 4E binding	G:9606:LARP1				LARP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARP1	0.41573328	0.2456964	72	4	FALSE	LARP1	LARP1	240.6527778	0	72	0	0.7657686	FALSE	0	LARP1	243962	0.06449583
790352	taxon:9606	2.40381282	6.57E-05	173245	1902	pescadillo ribosomal biogenesis factor 1	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0008283-&&-cell proliferation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007000-&&-nucleolus organization-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000466-&&-maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0070545-&&-PeBoW complex-%%-GO:0016020-&&-membrane-%%-GO:0000793-&&-condensed chromosome-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:PES1				PES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PES1	0.41600577	0.27287785	72	4	FALSE	PES1	PES1	191.2428571	0	71	0	0.7660312	FALSE	1	PES1	152344	0.0510215
790579	taxon:9606	2.69072003	3.56E-04	172084	1902	LY6/PLAUR domain containing 3	gene	biological_process-&-1&-GO:0007160-&&-cell-matrix adhesion-%%-GO:0006501-&&-C-terminal protein lipidation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0046658-&&-anchored component of plasma membrane|molecular_function-&-1&-GO:0043236-&&-laminin binding	G:9606:LYPD3				LYPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYPD3	0.37164773	0.00821596	72	4	FALSE	LYPD3	LYPD3	47.52777778	0	72	0	0.71821333	FALSE	0	LYPD3	373892	0.02440837
792177	taxon:9606	2.48873484	3.36E-04	182475	1902	ADP ribosylation factor 1	gene	biological_process-&-1&-GO:0070142-&&-synaptic vesicle budding-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:1902953-&&-positive regulation of ER to Golgi vesicle-mediated transport-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0055108-&&-Golgi to transport vesicle transport-%%-GO:1903725-&&-regulation of phospholipid metabolic process-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0097061-&&-dendritic spine organization-%%-GO:0007015-&&-actin filament organization-%%-GO:1902307-&&-positive regulation of sodium ion transmembrane transport-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0034379-&&-very-low-density lipoprotein particle assembly-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0097212-&&-lysosomal membrane organization-%%-GO:1902824-&&-positive regulation of late endosome to lysosome transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0030137-&&-COPI-coated vesicle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0031252-&&-cell leading edge-%%-GO:0030017-&&-sarcomere-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:1990583-&&-phospholipase D activator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor	G:9606:ARF1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa05110-&&-Vibrio cholerae infection	ARF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF1	0.40181058	0.0931677	72	4	FALSE	ARF1	ARF1	122.3428571	0	71	0	0.75187753	FALSE	1	ARF1	408312	0.03810266
792239	taxon:9606	2.46084764	2.11E-04	182364	1902	ATP synthase, H+ transporting, mitochondrial Fo complex subunit B1	gene	biological_process-&-1&-GO:0015986-&&-ATP synthesis coupled proton transport-%%-GO:0021762-&&-substantia nigra development-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000276-&&-mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism	G:9606:ATP5F1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5F1	0.40636404	0.15571205	72	4	FALSE	ATP5F1	ATP5F1	137.0694444	0	72	0	0.75652539	FALSE	0	ATP5F1	354674	0.04053288
792258	taxon:9606	2.56562155	4.48E-05	182339	1902	ATRX, chromatin remodeler	gene	biological_process-&-1&-GO:0070192-&&-chromosome organization involved in meiotic cell cycle-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0031297-&&-replication fork processing-%%-GO:0010571-&&-positive regulation of nuclear cell cycle DNA replication-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006306-&&-DNA methylation-%%-GO:1901581-&&-negative regulation of telomeric RNA transcription from RNA pol II promoter-%%-GO:1904908-&&-negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030900-&&-forebrain development-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0007283-&&-spermatogenesis-%%-GO:1900112-&&-regulation of histone H3-K9 trimethylation-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035128-&&-post-embryonic forelimb morphogenesis-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:1901582-&&-positive regulation of telomeric RNA transcription from RNA pol II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006310-&&-DNA recombination-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0070198-&&-protein localization to chromosome, telomeric region|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0031933-&&-telomeric heterochromatin-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0070603-&&-SWI/SNF superfamily-type complex-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:1990707-&&-nuclear subtelomeric heterochromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0015616-&&-DNA translocase activity-%%-GO:0004386-&&-helicase activity	G:9606:ATRX	ATRX	TRUE		ATRX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATRX	0.3897691	0.30907668	72	4	FALSE	ATRX	ATRX	196.2361111	0	72	0	0.73906307	FALSE	0	ATRX	140170	0.07116229
792290	taxon:9606	2.36237593	2.34E-04	182282	1902	cyclin dependent kinase 7	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070985-&&-TFIIK complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity	G:9606:CDK7			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	CDK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK7	0.42330265	0.14534161	72	4	FALSE	CDK7	CDK7	171.9428571	0	71	0	0.77293735	FALSE	1	CDK7	354152	0.04290349
792587	taxon:9606	2.58074681	2.83E-04	181760	1902	atrophin 1	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:ATN1				ATN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATN1	0.38748474	0.02898551	72	4	FALSE	ATN1	ATN1	76.5	0	71	0	0.7365422	FALSE	1	ATN1	289920	0.02923473
792794	taxon:9606	2.38742713	1.47E-04	181359	1902	eukaryotic translation initiation factor 2 subunit alpha	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0006413-&&-translational initiation-%%-GO:0034605-&&-cellular response to heat-%%-GO:1990737-&&-response to manganese-induced endoplasmic reticulum stress-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0007568-&&-aging-%%-GO:0034644-&&-cellular response to UV-%%-GO:1905098-&&-negative regulation of guanyl-nucleotide exchange factor activity-%%-GO:2000676-&&-positive regulation of type B pancreatic cell apoptotic process-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005850-&&-eukaryotic translation initiation factor 2 complex-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0044207-&&-translation initiation ternary complex-%%-GO:0043614-&&-multi-eIF complex-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0033290-&&-eukaryotic 48S preinitiation complex-%%-GO:0005634-&&-nucleus-%%-GO:0005840-&&-ribosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016020-&&-membrane-%%-GO:0097451-&&-glial limiting end-foot|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:EIF2S1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	EIF2S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2S1	0.41886095	0.15962441	72	4	FALSE	EIF2S1	EIF2S1	199.4027778	0	72	0	0.76876214	FALSE	0	EIF2S1	259808	0.05192057
793163	taxon:9606	2.43752954	5.80E-04	180615	1902	G protein subunit alpha i3	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0051301-&&-cell division-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0006906-&&-vesicle fusion-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0046039-&&-GTP metabolic process-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0042588-&&-zymogen granule-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI3	GNAI3	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04916-&&-Melanogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05030-&&-Cocaine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI3	0.41025144	0.08240166	72	4	FALSE	GNAI3	GNAI3	116.9142857	0	71	0	0.76041174	FALSE	1	GNAI3	587576	0.0331388
793281	taxon:9606	2.45470301	3.53E-05	180382	1902	histone cluster 1 H2A family member e	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AE			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AE	0.40738126	0.4194617	72	4	FALSE	HIST1H2AE	HIST1H2AE	260.4714286	0	71	0	0.7575495	FALSE	1	HIST1H2AE	141228	0.07578453
793290	taxon:9606	2.36678746	1.43E-04	180370	1902	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0032868-&&-response to insulin-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016507-&&-mitochondrial fatty acid beta-oxidation multienzyme complex|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0003985-&&-acetyl-CoA C-acetyltransferase activity-%%-GO:0016508-&&-long-chain-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016509-&&-long-chain-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0000062-&&-fatty-acyl-CoA binding-%%-GO:0051287-&&-NAD binding	G:9606:HADHA	HADHA	TRUE	KEGG-&-1&-hsa00410-&&-beta-Alanine metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00062-&&-Fatty acid elongation-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00071-&&-Fatty acid degradation	HADHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HADHA	0.42251365	0.10054773	72	4	FALSE	HADHA	HADHA	209.7638889	0	72	0	0.77220209	FALSE	0	HADHA	320808	0.05287021
787432	taxon:9606	2.41736253	3.38E-04	179445	1902	galectin 1	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046598-&&-positive regulation of viral entry into host cell-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0002317-&&-plasma cell differentiation-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0034120-&&-positive regulation of erythrocyte aggregation-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0048678-&&-response to axon injury-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0035900-&&-response to isolation stress-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0030395-&&-lactose binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003723-&&-RNA binding-%%-GO:0043236-&&-laminin binding	G:9606:LGALS1				LGALS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS1	0.41367399	0.10741688	71	4	FALSE	LGALS1	LGALS1	155.6811594	0	70	0	0.76377291	FALSE	1	LGALS1	420482	0.04267554
787814	taxon:9606	2.4230345	3.10E-04	178755	1902	protein kinase C epsilon	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035669-&&-TRAM-dependent toll-like receptor 4 signaling pathway-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:2001031-&&-positive regulation of cellular glucuronidation-%%-GO:0051301-&&-cell division-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0070257-&&-positive regulation of mucus secretion-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0007049-&&-cell cycle-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0030168-&&-platelet activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0043278-&&-response to morphine-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0050996-&&-positive regulation of lipid catabolic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0035276-&&-ethanol binding-%%-GO:0005515-&&-protein binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004699-&&-calcium-independent protein kinase C activity-%%-GO:0005524-&&-ATP binding-%%-GO:0030546-&&-receptor activator activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0019899-&&-enzyme binding	G:9606:PRKCE			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04530-&&-Tight junction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04022-&&-cGMP-PKG signaling pathway	PRKCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCE	0.41270564	0.08780904	71	5	FALSE	PRKCE	PRKCE	122.5942029	0	70	0	0.76282758	FALSE	1	PRKCE	377458	0.03392339
788011	taxon:9606	2.50228454	1.60E-04	178397	1902	prefoldin subunit 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016272-&&-prefoldin complex|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:PFDN5				PFDN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFDN5	0.39963481	0.0917505	71	4	FALSE	PFDN5	PFDN5	110.6760563	0	71	0	0.74961924	FALSE	0	PFDN5	231222	0.03530115
788240	taxon:9606	2.35134709	2.45E-04	178020	1902	serine hydroxymethyltransferase 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0019264-&&-glycine biosynthetic process from serine-%%-GO:0006564-&&-L-serine biosynthetic process-%%-GO:0034340-&&-response to type I interferon-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0051262-&&-protein tetramerization-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006563-&&-L-serine metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0070552-&&-BRISC complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008732-&&-L-allo-threonine aldolase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004372-&&-glycine hydroxymethyltransferase activity-%%-GO:0016597-&&-amino acid binding	G:9606:SHMT2			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa01523-&&-Antifolate resistance-%%-hsa00260-&&-Glycine, serine and threonine metabolism	SHMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHMT2	0.42528813	0.10869565	71	4	FALSE	SHMT2	SHMT2	188.2173913	0	70	0	0.77477548	FALSE	1	SHMT2	420938	0.04625711
788578	taxon:9606	2.49834568	2.28E-04	177405	1902	transaldolase 1	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0009052-&&-pentose-phosphate shunt, non-oxidative branch-%%-GO:0005999-&&-xylulose biosynthetic process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004801-&&-sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0048029-&&-monosaccharide binding	G:9606:TALDO1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00030-&&-Pentose phosphate pathway	TALDO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TALDO1	0.40026487	0.11466326	71	4	FALSE	TALDO1	TALDO1	122.1014493	0	70	0	0.75027572	FALSE	1	TALDO1	327286	0.03859234
788641	taxon:9606	2.33480384	1.76E-04	177269	1902	aminoacyl tRNA synthetase complex interacting multifunctional protein 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0060510-&&-Type II pneumocyte differentiation-%%-GO:0031398-&&-positive regulation of protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AIMP2				AIMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIMP2	0.4283015	0.12659847	71	4	FALSE	AIMP2	AIMP2	169.0869565	0	70	0	0.77753269	FALSE	1	AIMP2	308156	0.0404964
789000	taxon:9606	2.54009768	2.12E-04	176431	1902	YEATS domain containing 4	gene	biological_process-&-1&-GO:0007067-&&-mitotic nuclear division-%%-GO:0040008-&&-regulation of growth-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016363-&&-nuclear matrix-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:YEATS4				YEATS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YEATS4	0.39368565	0.10623742	71	4	FALSE	YEATS4	YEATS4	105.2676056	0	71	0	0.74331705	FALSE	0	YEATS4	281638	0.03631322
789209	taxon:9606	2.37340476	1.44E-04	175998	1902	COP9 signalosome subunit 3	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0000338-&&-protein deneddylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0009416-&&-response to light stimulus-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS3				COPS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS3	0.42133563	0.2173913	71	4	FALSE	COPS3	COPS3	188.057971	0	70	0	0.77109921	FALSE	1	COPS3	289482	0.04782019
789609	taxon:9606	2.40838191	1.81E-04	175060	1902	mediator complex subunit 12	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:1990403-&&-embryonic brain development-%%-GO:0007492-&&-endoderm development-%%-GO:0007507-&&-heart development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0014044-&&-Schwann cell development-%%-GO:0021510-&&-spinal cord development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0001843-&&-neural tube closure-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0090245-&&-axis elongation involved in somitogenesis-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004872-&&-receptor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:MED12			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED12	0.41521654	0.2084399	71	4	FALSE	MED12	MED12	145.0724638	0	70	0	0.76526968	FALSE	1	MED12	316648	0.03900726
789764	taxon:9606	2.35213487	2.21E-04	174743	1902	protein disulfide isomerase family A member 6	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PDIA6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PDIA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA6	0.42514569	0.11589537	71	4	FALSE	PDIA6	PDIA6	226.7042254	0	71	0	0.77464419	FALSE	0	PDIA6	441776	0.05590386
789832	taxon:9606	2.38837246	1.02E-04	174547	1902	transcription elongation regulator 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:TCERG1			KEGG-&-1&-hsa03040-&&-Spliceosome	TCERG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCERG1	0.41869516	0.17625755	71	4	FALSE	TCERG1	TCERG1	203.6619718	0	71	0	0.76860459	FALSE	0	TCERG1	237804	0.05310895
790070	taxon:9606	2.33054987	1.35E-04	173955	1902	serine/threonine kinase receptor associated protein	gene	biological_process-&-1&-GO:0030277-&&-maintenance of gastrointestinal epithelium-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:STRAP			KEGG-&-1&-hsa03013-&&-RNA transport	STRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRAP	0.42908329	0.1172208	71	4	FALSE	STRAP	STRAP	206.826087	0	70	0	0.77824169	FALSE	1	STRAP	319874	0.04906906
790441	taxon:9606	2.57286907	3.99E-04	172941	1902	NUFIP1, FMR1 interacting protein 1	gene	biological_process-&-1&-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:0006396-&&-RNA processing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051259-&&-protein oligomerization|cellular_component-&-1&-GO:0070761-&&-pre-snoRNP complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0016363-&&-nuclear matrix-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0005726-&&-perichromatin fibrils-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NUFIP1				NUFIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUFIP1	0.38867116	0.02514919	71	4	FALSE	NUFIP1	NUFIP1	74.97101449	0	70	0	0.73785515	FALSE	1	NUFIP1	418128	0.02788651
790865	taxon:9606	2.44162597	1.69E-04	170846	1902	5'-3' exoribonuclease 1	gene	biological_process-&-1&-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0071028-&&-nuclear mRNA surveillance-%%-GO:0033574-&&-response to testosterone-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0016075-&&-rRNA catabolic process-%%-GO:0071409-&&-cellular response to cycloheximide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0004534-&&-5'-3' exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding	G:9606:XRN1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03018-&&-RNA degradation	XRN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRN1	0.40956314	0.11911469	71	4	FALSE	XRN1	XRN1	160.8450704	0	71	0	0.75972901	FALSE	0	XRN1	287168	0.04555321
791276	taxon:9606	2.39057823	2.08E-04	169405	1902	regulatory associated protein of MTOR complex 1	gene	biological_process-&-1&-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0016236-&&-macroautophagy-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0008361-&&-regulation of cell size-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0016049-&&-cell growth-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0031929-&&-TOR signaling-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0031931-&&-TORC1 complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0001156-&&-TFIIIC-class transcription factor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0001031-&&-RNA polymerase III type 2 promoter DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0001030-&&-RNA polymerase III type 1 promoter DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0001032-&&-RNA polymerase III type 3 promoter DNA binding	G:9606:RPTOR			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04136-&&-Autophagy - other-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	RPTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPTOR	0.41830884	0.11167945	71	4	FALSE	RPTOR	RPTOR	152.7826087	0	70	0	0.76823696	FALSE	1	RPTOR	313960	0.03993559
791692	taxon:9606	2.63242477	2.20E-04	167407	1902	centrosomal protein 44	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0030496-&&-midbody-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP44				CEP44	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP44	0.3798779	0.06156942	71	4	FALSE	CEP44	CEP44	66.71830986	0	71	0	0.72792921	FALSE	0	CEP44	239360	0.02872242
792208	taxon:9606	2.46778005	2.74E-04	182415	1902	argininosuccinate synthase 1	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0000053-&&-argininosuccinate metabolic process-%%-GO:0006526-&&-arginine biosynthetic process-%%-GO:0006531-&&-aspartate metabolic process-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0000052-&&-citrulline metabolic process-%%-GO:1903038-&&-negative regulation of leukocyte cell-cell adhesion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004055-&&-argininosuccinate synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0016597-&&-amino acid binding	G:9606:ASS1			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa01100-&&-Metabolic pathways	ASS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASS1	0.4052225	0.09633419	71	4	FALSE	ASS1	ASS1	112.7681159	0	70	0	0.75536999	FALSE	1	ASS1	313696	0.03369793
792473	taxon:9606	2.47124626	1.65E-04	181964	1902	BCL2 associated athanogene 1	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding	G:9606:BAG1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	BAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG1	0.40465413	0.10342052	71	4	FALSE	BAG1	BAG1	127.4788732	0	71	0	0.75479229	FALSE	0	BAG1	262424	0.03843817
792695	taxon:9606	2.36410903	2.22E-04	181548	1902	DEAD-box helicase 6	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006417-&&-regulation of translation-%%-GO:0019074-&&-viral RNA genome packaging-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|cellular_component-&-1&-GO:0001520-&&-outer dense fiber-%%-GO:0000792-&&-heterochromatin-%%-GO:0043186-&&-P granule-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0097227-&&-sperm annulus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003724-&&-RNA helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004386-&&-helicase activity-%%-GO:0045296-&&-cadherin binding	G:9606:DDX6			KEGG-&-1&-hsa03018-&&-RNA degradation	DDX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX6	0.42299234	0.1110664	71	4	FALSE	DDX6	DDX6	203.1830986	0	71	0	0.7726485	FALSE	0	DDX6	410588	0.05099843
792870	taxon:9606	2.47313692	2.12E-04	181245	1902	electron transfer flavoprotein alpha subunit	gene	biological_process-&-1&-GO:0022904-&&-respiratory electron transport chain-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0005515-&&-protein binding	G:9606:ETFA				ETFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETFA	0.40434478	0.09859155	71	4	FALSE	ETFA	ETFA	126.7183099	0	71	0	0.75447718	FALSE	0	ETFA	296866	0.03827802
792938	taxon:9606	2.48148732	2.64E-04	181112	1902	protein tyrosine kinase 2 beta	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:2000538-&&-positive regulation of B cell chemotaxis-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0045087-&&-innate immune response-%%-GO:0002315-&&-marginal zone B cell differentiation-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001556-&&-oocyte maturation-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0009749-&&-response to glucose-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0030826-&&-regulation of cGMP biosynthetic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010656-&&-negative regulation of muscle cell apoptotic process-%%-GO:0051592-&&-response to calcium ion-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0042220-&&-response to cocaine-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0042976-&&-activation of Janus kinase activity-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0051591-&&-response to cAMP-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0031175-&&-neuron projection development-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0009725-&&-response to hormone-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007172-&&-signal complex assembly-%%-GO:0032960-&&-regulation of inositol trisphosphate biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0010226-&&-response to lithium ion-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045453-&&-bone resorption-%%-GO:0006968-&&-cellular defense response-%%-GO:0045471-&&-response to ethanol-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0010758-&&-regulation of macrophage chemotaxis-%%-GO:0006950-&&-response to stress-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0006461-&&-protein complex assembly-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:2000058-&&-regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0006915-&&-apoptotic process-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0010752-&&-regulation of cGMP-mediated signaling-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001525-&&-angiogenesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046330-&&-positive regulation of JNK cascade|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030425-&&-dendrite-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0097440-&&-apical dendrite-%%-GO:0043025-&&-neuronal cell body-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043423-&&-3-phosphoinositide-dependent protein kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004972-&&-NMDA glutamate receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0032403-&&-protein complex binding	G:9606:PTK2B			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection	PTK2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTK2B	0.40298413	0.17604433	71	4	FALSE	PTK2B	PTK2B	121	0	70	0	0.75308545	FALSE	1	PTK2B	316696	0.03715771
792989	taxon:9606	2.40066173	2.58E-04	181039	1902	filamin C	gene	biological_process-&-1&-GO:0048747-&&-muscle fiber development-%%-GO:0034329-&&-cell junction assembly|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0042383-&&-sarcolemma-%%-GO:0043034-&&-costamere-%%-GO:0016528-&&-sarcoplasm|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0030506-&&-ankyrin binding	G:9606:FLNC			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	FLNC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLNC	0.41655181	0.08289738	71	4	FALSE	FLNC	FLNC	164.1126761	0	71	0	0.76655638	FALSE	0	FLNC	390144	0.04378044
793168	taxon:9606	2.39089334	4.87E-04	180606	1902	G protein subunit beta 1	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006457-&&-protein folding-%%-GO:0007165-&&-signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0050909-&&-sensory perception of taste-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008283-&&-cell proliferation-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0071870-&&-cellular response to catecholamine stimulus-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0016056-&&-rhodopsin mediated signaling pathway-%%-GO:0010659-&&-cardiac muscle cell apoptotic process-%%-GO:0030168-&&-platelet activation-%%-GO:0071377-&&-cellular response to glucagon stimulus|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0042622-&&-photoreceptor outer segment membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body-%%-GO:0097381-&&-photoreceptor disc membrane-%%-GO:0005622-&&-intracellular-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0047391-&&-alkylglycerophosphoethanolamine phosphodiesterase activity	G:9606:GNB1	GNB1	TRUE	KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04744-&&-Phototransduction-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04740-&&-Olfactory transduction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB1	0.41825371	0.07042254	71	4	FALSE	GNB1	GNB1	143.943662	0	71	0	0.76818444	FALSE	0	GNB1	577450	0.0377385
793223	taxon:9606	2.55081141	4.00E-04	180507	1902	heat shock protein family B (small) member 2	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008047-&&-enzyme activator activity-%%-GO:0005515-&&-protein binding	G:9606:HSPB2			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	HSPB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB2	0.39203212	0.04262575	71	4	FALSE	HSPB2	HSPB2	90.07246377	0	70	0	0.74153143	FALSE	1	HSPB2	440682	0.03206082
787379	taxon:9606	2.37482275	8.11E-05	179528	1902	myosin heavy chain 10	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0007512-&&-adult heart development-%%-GO:0001764-&&-neuron migration-%%-GO:0021680-&&-cerebellar Purkinje cell layer development-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0001778-&&-plasma membrane repair-%%-GO:0007411-&&-axon guidance-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008283-&&-cell proliferation-%%-GO:0098885-&&-modification of postsynaptic actin cytoskeleton-%%-GO:0007155-&&-cell adhesion-%%-GO:0021678-&&-third ventricle development-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0003279-&&-cardiac septum development-%%-GO:0007097-&&-nuclear migration-%%-GO:0035904-&&-aorta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0021592-&&-fourth ventricle development-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0006887-&&-exocytosis-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0016460-&&-myosin II complex-%%-GO:0042641-&&-actomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0016459-&&-myosin complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0097513-&&-myosin II filament-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0030027-&&-lamellipodium-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043531-&&-ADP binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0003779-&&-actin binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYH10			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYH10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH10	0.42108406	0.1320911	70	4	FALSE	MYH10	MYH10	219.6571429	0	70	0	0.77086287	FALSE	0	MYH10	230898	0.05614227
787478	taxon:9606	2.36741768	2.15E-04	179356	1902	ataxin 3	gene	biological_process-&-1&-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1904379-&&-protein localization to cytosolic proteasome complex involved in ERAD pathway-%%-GO:1904294-&&-positive regulation of ERAD pathway-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0010810-&&-regulation of cell-substrate adhesion-%%-GO:0071218-&&-cellular response to misfolded protein-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0034605-&&-cellular response to heat-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042405-&&-nuclear inclusion body|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:ATXN3			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	ATXN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN3	0.42240117	0.11369622	70	4	FALSE	ATXN3	ATXN3	169.3382353	0	69	0	0.77209705	FALSE	1	ATXN3	333276	0.04277974
787734	taxon:9606	2.51221049	1.78E-04	178856	1902	RNA polymerase II subunit G	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0000291-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:POLR2G			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2G	0.39805582	0.17471466	70	4	FALSE	POLR2G	POLR2G	109.6764706	0	69	0	0.74796492	FALSE	1	POLR2G	268358	0.0356425
788222	taxon:9606	2.33874271	8.56E-05	178052	1902	replication factor C subunit 4	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031390-&&-Ctf18 RFC-like complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:RFC4			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC4	0.42758017	0.23395445	70	4	FALSE	RFC4	RFC4	223.7571429	0	70	0	0.77687621	FALSE	0	RFC4	231802	0.0538525
788695	taxon:9606	2.45486056	2.20E-04	177170	1902	TNF alpha induced protein 3	gene	biological_process-&-1&-GO:0072573-&&-tolerance induction to lipopolysaccharide-%%-GO:0006915-&&-apoptotic process-%%-GO:0061043-&&-regulation of vascular wound healing-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0070433-&&-negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0070429-&&-negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0072666-&&-establishment of protein localization to vacuole-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0035871-&&-protein K11-linked deubiquitination-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0050691-&&-regulation of defense response to virus by host-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0034140-&&-negative regulation of toll-like receptor 3 signaling pathway-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:2000349-&&-negative regulation of CD40 signaling pathway-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0034144-&&-negative regulation of toll-like receptor 4 signaling pathway-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0034136-&&-negative regulation of toll-like receptor 2 signaling pathway-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050869-&&-negative regulation of B cell activation-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0051259-&&-protein oligomerization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0001922-&&-B-1 B cell homeostasis-%%-GO:0071947-&&-protein deubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0090291-&&-negative regulation of osteoclast proliferation-%%-GO:0002677-&&-negative regulation of chronic inflammatory response-%%-GO:0034148-&&-negative regulation of toll-like receptor 5 signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0002020-&&-protease binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0043621-&&-protein self-association-%%-GO:0008270-&&-zinc ion binding	G:9606:TNFAIP3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis	TNFAIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFAIP3	0.40735511	0.14223003	70	4	FALSE	TNFAIP3	TNFAIP3	138.6764706	0	69	0	0.75752324	FALSE	1	TNFAIP3	299230	0.04055089
788757	taxon:9606	2.44036553	2.19E-04	176996	1902	tripartite motif containing 25	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045087-&&-innate immune response-%%-GO:0036503-&&-ERAD pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0033280-&&-response to vitamin D-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0043627-&&-response to estrogen-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:1902186-&&-regulation of viral release from host cell-%%-GO:0046596-&&-regulation of viral entry into host cell-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051607-&&-defense response to virus-%%-GO:0019985-&&-translesion synthesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0045296-&&-cadherin binding	G:9606:TRIM25			KEGG-&-1&-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A	TRIM25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM25	0.40977468	0.08955224	70	4	FALSE	TRIM25	TRIM25	161.2058824	0	69	0	0.75993908	FALSE	1	TRIM25	315170	0.04583298
789144	taxon:9606	2.41673231	2.38E-04	176119	1902	suppressor of cytokine signaling 3	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0060708-&&-spongiotrophoblast differentiation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042512-&&-negative regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0060707-&&-trophoblast giant cell differentiation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0040008-&&-regulation of growth-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:SOCS3	SOCS3	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04931-&&-Insulin resistance-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS3	0.41378186	0.0989648	70	4	FALSE	SOCS3	SOCS3	125.7571429	0	70	0	0.76387795	FALSE	0	SOCS3	347996	0.03447154
789464	taxon:9606	2.5174098	1.81E-04	175414	1902	VPS26, retromer complex component A	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0030906-&&-retromer, cargo-selective complex-%%-GO:0030904-&&-retromer complex-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome-%%-GO:0031982-&&-vesicle-%%-GO:0010008-&&-endosome membrane-%%-GO:0097422-&&-tubular endosome|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:VPS26A			KEGG-&-1&-hsa04144-&&-Endocytosis	VPS26A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS26A	0.3972337	0.06892011	70	4	FALSE	VPS26A	VPS26A	100.4558824	0	69	0	0.74709837	FALSE	1	VPS26A	225316	0.0331587
789765	taxon:9606	2.30092957	1.90E-04	174742	1902	TNF receptor associated protein 1	gene	biological_process-&-1&-GO:0006950-&&-response to stress-%%-GO:1903751-&&-negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:1903427-&&-negative regulation of reactive oxygen species biosynthetic process-%%-GO:0009386-&&-translational attenuation-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:1901856-&&-negative regulation of cellular respiration|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005811-&&-lipid particle-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:TRAP1				TRAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAP1	0.43460696	0.13126294	70	4	FALSE	TRAP1	TRAP1	217.5142857	0	70	0	0.7831784	FALSE	0	TRAP1	348204	0.04965753
789803	taxon:9606	2.57602017	2.90E-04	174631	1902	sprouty RTK signaling antagonist 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0060437-&&-lung growth-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0051387-&&-negative regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045165-&&-cell fate commitment-%%-GO:0031345-&&-negative regulation of cell projection organization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity	G:9606:SPRY2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	SPRY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRY2	0.38819572	0.08823529	70	4	FALSE	SPRY2	SPRY2	83	0	69	0	0.73732997	FALSE	1	SPRY2	326970	0.03123893
790035	taxon:9606	2.44477706	2.64E-04	174050	1902	WW domain containing E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007417-&&-central nervous system development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:WWP1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis	WWP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWP1	0.40903525	0.07111501	70	4	FALSE	WWP1	WWP1	122.7352941	0	69	0	0.75920382	FALSE	1	WWP1	337436	0.03521472
790307	taxon:9606	2.49440681	1.88E-04	173367	1902	MOB family member 4, phocein	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:MOB4				MOB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOB4	0.40089692	0.09979296	70	4	FALSE	MOB4	MOB4	114.2285714	0	70	0	0.7509322	FALSE	0	MOB4	257510	0.03586922
790375	taxon:9606	2.39577753	9.00E-05	173187	1902	GTP binding protein 4	gene	biological_process-&-1&-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0033342-&&-negative regulation of collagen binding-%%-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0050821-&&-protein stabilization-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030336-&&-negative regulation of cell migration|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003723-&&-RNA binding	G:9606:GTPBP4			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GTPBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTPBP4	0.41740103	0.29482402	70	4	FALSE	GTPBP4	GTPBP4	225.4857143	0	70	0	0.76737041	FALSE	0	GTPBP4	190378	0.05939335
790391	taxon:9606	2.46132031	1.89E-04	173129	1902	nucleoporin 62	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0042306-&&-regulation of protein import into nucleus-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0071426-&&-ribonucleoprotein complex export from nucleus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0008219-&&-cell death-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007569-&&-cell aging-%%-GO:0016925-&&-protein sumoylation-%%-GO:0019083-&&-viral transcription-%%-GO:0016032-&&-viral process-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000922-&&-spindle pole-%%-GO:0044613-&&-nuclear pore central transport channel-%%-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0046930-&&-pore complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005642-&&-annulate lamellae-%%-GO:0090543-&&-Flemming body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0031074-&&-nucleocytoplasmic shuttling complex|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0051425-&&-PTB domain binding-%%-GO:0051879-&&-Hsp90 protein binding	G:9606:NUP62			KEGG-&-1&-hsa03013-&&-RNA transport	NUP62	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP62	0.40628601	0.09306409	70	4	FALSE	NUP62	NUP62	145.8823529	0	69	0	0.75644662	FALSE	1	NUP62	283214	0.0429941
790453	taxon:9606	2.51000473	1.48E-04	172810	1902	UPF2 regulator of nonsense transcripts homolog (yeast)	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0001889-&&-liver development-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0035145-&&-exon-exon junction complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding	G:9606:UPF2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF2	0.39840562	0.06760316	70	4	FALSE	UPF2	UPF2	107.1470588	0	69	0	0.74833255	FALSE	1	UPF2	204762	0.03474199
790785	taxon:9606	2.47408224	3.31E-04	171218	1902	ECSIT signalling integrator	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051341-&&-regulation of oxidoreductase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016651-&&-oxidoreductase activity, acting on NAD(P)H-%%-GO:0005515-&&-protein binding	G:9606:ECSIT			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	ECSIT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECSIT	0.40419028	0.08691835	70	4	FALSE	ECSIT	ECSIT	96.76470588	0	69	0	0.75431963	FALSE	1	ECSIT	334846	0.02942967
790885	taxon:9606	2.54356389	2.59E-05	170777	1902	ribosomal protein S27 like	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006412-&&-translation-%%-GO:0000028-&&-ribosomal small subunit assembly-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008494-&&-translation activator activity-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RPS27L			KEGG-&-1&-hsa03010-&&-Ribosome	RPS27L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS27L	0.39314916	0.52960663	70	4	FALSE	RPS27L	RPS27L	180.6571429	0	70	0	0.74273935	FALSE	0	RPS27L	71654	0.06269648
791035	taxon:9606	2.62564991	1.73E-04	170291	1902	nuclear receptor binding SET domain protein 3	gene	biological_process-&-1&-GO:0016571-&&-histone methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:NSD3			KEGG-&-1&-hsa00310-&&-Lysine degradation	NSD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSD3	0.38085809	0.21035197	70	4	FALSE	NSD3	NSD3	173.8428571	0	70	0	0.72905835	FALSE	0	NSD3	331174	0.07342193
791078	taxon:9606	2.52134867	1.86E-04	170127	1902	developmental pluripotency associated 4	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DPPA4				DPPA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPPA4	0.39661314	0.09086918	70	4	FALSE	DPPA4	DPPA4	109.3235294	0	69	0	0.74644189	FALSE	1	DPPA4	277850	0.03630515
791477	taxon:9606	2.55664093	3.42E-04	168475	1902	NGG1 interacting factor 3 like 1	gene	biological_process-&-1&-GO:0030182-&&-neuron differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding	G:9606:NIF3L1				NIF3L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NIF3L1	0.39113823	0.07155399	70	4	FALSE	NIF3L1	NIF3L1	82.79411765	0	69	0	0.74055984	FALSE	1	NIF3L1	374352	0.0296544
791818	taxon:9606	2.57318418	1.09E-04	166711	1902	tripartite motif containing 55	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM55				TRIM55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM55	0.38862356	0.10623354	70	4	FALSE	TRIM55	TRIM55	105.8088235	0	69	0	0.73780264	FALSE	1	TRIM55	170276	0.03910156
792254	taxon:9606	2.39530487	2.00E-04	182346	1902	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	gene	biological_process-&-1&-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0015992-&&-proton transport-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005215-&&-transporter activity	G:9606:ATP5O			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	ATP5O	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5O	0.41748339	0.1515528	70	4	FALSE	ATP5O	ATP5O	181.9571429	0	70	0	0.76744919	FALSE	0	ATP5O	396218	0.04798206
792685	taxon:9606	2.51898535	1.05E-04	181560	1902	damage specific DNA binding protein 2	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006281-&&-DNA repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0009411-&&-response to UV-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0070914-&&-UV-damage excision repair|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:DDB2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05216-&&-Thyroid cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DDB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDB2	0.39698524	0.1286216	70	4	FALSE	DDB2	DDB2	137.0147059	0	69	0	0.74683578	FALSE	1	DDB2	180602	0.04517015
793329	taxon:9606	2.57602017	2.27E-04	180314	1902	histidine triad nucleotide binding protein 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0009154-&&-purine ribonucleotide catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0016787-&&-hydrolase activity	G:9606:HINT1				HINT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HINT1	0.38819572	0.13388938	70	4	FALSE	HINT1	HINT1	99.32352941	0	69	0	0.73732997	FALSE	1	HINT1	302774	0.03719432
787093	taxon:9606	2.38002206	8.74E-05	180064	1902	IK cytokine, down-regulator of HLA II	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:IK				IK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IK	0.42016417	0.20759837	69	4	FALSE	IK	IK	195.7910448	0	68	0	0.76999632	FALSE	1	IK	200402	0.05027252
787269	taxon:9606	2.37025366	1.19E-04	179772	1902	lysyl-tRNA synthetase	gene	biological_process-&-1&-GO:0015966-&&-diadenosine tetraphosphate biosynthetic process-%%-GO:0006430-&&-lysyl-tRNA aminoacylation-%%-GO:0008033-&&-tRNA processing-%%-GO:0016032-&&-viral process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004824-&&-lysine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016597-&&-amino acid binding	G:9606:KARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	KARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KARS	0.42189577	0.15984655	69	4	FALSE	KARS	KARS	187.2463768	0	69	0	0.77162439	FALSE	0	KARS	234042	0.04749667
787396	taxon:9606	2.38411848	1.68E-04	179501	1902	protein phosphatase 1 regulatory subunit 12A	gene	biological_process-&-1&-GO:0035508-&&-positive regulation of myosin-light-chain-phosphatase activity-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0035507-&&-regulation of myosin-light-chain-phosphatase activity-%%-GO:0035690-&&-cellular response to drug-%%-GO:0007165-&&-signal transduction-%%-GO:0051297-&&-centrosome organization-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0031672-&&-A band-%%-GO:0000776-&&-kinetochore-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043292-&&-contractile fiber-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0019208-&&-phosphatase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:PPP1R12A			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP1R12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R12A	0.41944224	0.13256607	69	4	FALSE	PPP1R12A	PPP1R12A	171.6666667	0	69	0	0.76931359	FALSE	0	PPP1R12A	311158	0.04432813
787566	taxon:9606	2.39010556	2.33E-04	179161	1902	NADH:ubiquinone oxidoreductase core subunit S1	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0045333-&&-cellular respiration|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding	G:9606:NDUFS1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS1	0.41839156	0.20417732	69	4	FALSE	NDUFS1	NDUFS1	174.5652174	0	69	0	0.76831574	FALSE	0	NDUFS1	434674	0.04548768
787674	taxon:9606	2.40743658	2.70E-04	178969	1902	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0044029-&&-hypomethylation of CpG island-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0043276-&&-anoikis-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043457-&&-regulation of cellular respiration-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001944-&&-vasculature development-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:2000270-&&-negative regulation of fibroblast apoptotic process-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0001889-&&-liver development-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0097009-&&-energy homeostasis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0038028-&&-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:2000653-&&-regulation of genetic imprinting-%%-GO:0001525-&&-angiogenesis-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0016310-&&-phosphorylation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005943-&&-phosphatidylinositol 3-kinase complex, class IA-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PIK3CA			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3CA	0.41537958	0.08653026	69	4	FALSE	PIK3CA	PIK3CA	132.884058	0	69	0	0.76542724	FALSE	0	PIK3CA	356736	0.03580586
787929	taxon:9606	2.54183079	7.46E-05	178568	1902	origin recognition complex subunit 2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000808-&&-origin recognition complex-%%-GO:0000939-&&-condensed chromosome inner kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0000792-&&-heterochromatin|molecular_function-&-1&-GO:0003688-&&-DNA replication origin binding-%%-GO:0005515-&&-protein binding	G:9606:ORC2			KEGG-&-1&-hsa04110-&&-Cell cycle	ORC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORC2	0.39341722	0.21483492	69	4	FALSE	ORC2	ORC2	168.6268657	0	68	0	0.7430282	FALSE	1	ORC2	172524	0.05799177
788069	taxon:9606	2.35985505	5.42E-05	178284	1902	ribosomal protein L28	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0030425-&&-dendrite-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RPL28			KEGG-&-1&-hsa03010-&&-Ribosome	RPL28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL28	0.42375484	0.4799659	69	4	FALSE	RPL28	RPL28	267.0289855	0	69	0	0.77335749	FALSE	0	RPL28	166892	0.06646751
788366	taxon:9606	2.46305341	1.28E-04	177793	1902	signal recognition particle 14	gene	biological_process-&-1&-GO:0045047-&&-protein targeting to ER-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042493-&&-response to drug-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0006613-&&-cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005786-&&-signal recognition particle, endoplasmic reticulum targeting-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008312-&&-7S RNA binding-%%-GO:0030942-&&-endoplasmic reticulum signal peptide binding-%%-GO:0005515-&&-protein binding	G:9606:SRP14			KEGG-&-1&-hsa03060-&&-Protein export	SRP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRP14	0.40600013	0.1543052	69	4	FALSE	SRP14	SRP14	197.7971015	0	69	0	0.75615776	FALSE	0	SRP14	274652	0.05865459
788380	taxon:9606	2.3798645	1.90E-04	177775	1902	signal sequence receptor subunit 4	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005784-&&-Sec61 translocon complex-%%-GO:0070062-&&-extracellular exosome	G:9606:SSR4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SSR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSR4	0.42019199	0.13299233	69	4	FALSE	SSR4	SSR4	189.5652174	0	69	0	0.77002258	FALSE	0	SSR4	362464	0.04868403
788391	taxon:9606	2.36678746	2.90E-04	177748	1902	signal transducer and activator of transcription 5B	gene	biological_process-&-1&-GO:0006573-&&-valine metabolic process-%%-GO:0048541-&&-Peyer's patch development-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0007595-&&-lactation-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0070672-&&-response to interleukin-15-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0007565-&&-female pregnancy-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0038161-&&-prolactin signaling pathway-%%-GO:0070670-&&-response to interleukin-4-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0019915-&&-lipid storage-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0046544-&&-development of secondary male sexual characteristics-%%-GO:0032819-&&-positive regulation of natural killer cell proliferation-%%-GO:0046543-&&-development of secondary female sexual characteristics-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0006549-&&-isoleucine metabolic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0001553-&&-luteinization-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0030856-&&-regulation of epithelial cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032825-&&-positive regulation of natural killer cell differentiation-%%-GO:0000255-&&-allantoin metabolic process-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0045588-&&-positive regulation of gamma-delta T cell differentiation-%%-GO:0097531-&&-mast cell migration-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019218-&&-regulation of steroid metabolic process-%%-GO:0070669-&&-response to interleukin-2|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:STAT5B			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis	STAT5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT5B	0.42251365	0.15513342	69	4	FALSE	STAT5B	STAT5B	144.119403	0	68	0	0.77220209	FALSE	1	STAT5B	384452	0.03632581
788401	taxon:9606	2.52544509	2.61E-04	177738	1902	serine/threonine kinase 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0007417-&&-central nervous system development-%%-GO:0060215-&&-primitive hemopoiesis-%%-GO:0001841-&&-neural tube formation-%%-GO:0003157-&&-endocardium development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060800-&&-regulation of cell differentiation involved in embryonic placenta development-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0004672-&&-protein kinase activity	G:9606:STK3			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	STK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK3	0.3959698	0.07779285	69	4	FALSE	STK3	STK3	96.73134328	0	68	0	0.74575915	FALSE	1	STK3	293788	0.03235497
788497	taxon:9606	2.48873484	9.92E-05	177550	1902	small nuclear ribonucleoprotein polypeptide C	gene	biological_process-&-1&-GO:0000395-&&-mRNA 5'-splice site recognition-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0000243-&&-commitment complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071010-&&-prespliceosome-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0030619-&&-U1 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030627-&&-pre-mRNA 5'-splice site binding-%%-GO:1990446-&&-U1 snRNP binding	G:9606:SNRPC			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPC	0.40181058	0.2039801	69	4	FALSE	SNRPC	SNRPC	202.8358209	0	68	0	0.75187753	FALSE	1	SNRPC	228644	0.06290971
788830	taxon:9606	2.3763983	1.85E-04	176798	1902	upstream binding transcription factor, RNA polymerase I	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006360-&&-transcription from RNA polymerase I promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:1902659-&&-regulation of glucose mediated signaling pathway|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0001165-&&-RNA polymerase I upstream control element sequence-specific DNA binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:UBTF				UBTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBTF	0.42080488	0.12890095	69	4	FALSE	UBTF	UBTF	201.7014925	0	68	0	0.77060028	FALSE	1	UBTF	319726	0.05126921
789071	taxon:9606	2.7444462	2.20E-04	159860	1902	keratin associated protein 10-8	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KRTAP10-8				KRTAP10-8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-8	0.36437224	0.15649028	69	4	FALSE	KRTAP10-8	KRTAP10-8	49.3880597	0	68	0	0.70925897	FALSE	1	KRTAP10-8	357642	0.03015162
789266	taxon:9606	2.41342366	2.77E-04	175875	1902	beclin 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0032801-&&-receptor catabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0045324-&&-late endosome to vacuole transport-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:1902425-&&-positive regulation of attachment of mitotic spindle microtubules to kinetochore-%%-GO:0032258-&&-CVT pathway-%%-GO:0006914-&&-autophagy-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:2000786-&&-positive regulation of autophagosome assembly-%%-GO:0006968-&&-cellular defense response-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0000910-&&-cytokinesis-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0042493-&&-response to drug-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0048666-&&-neuron development-%%-GO:0071275-&&-cellular response to aluminum ion-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0044804-&&-nucleophagy-%%-GO:0001666-&&-response to hypoxia-%%-GO:0033197-&&-response to vitamin E-%%-GO:0043652-&&-engulfment of apoptotic cell-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0007568-&&-aging-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:1905672-&&-negative regulation of lysosome organization-%%-GO:0010040-&&-response to iron(II) ion-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000422-&&-mitophagy-%%-GO:0051607-&&-defense response to virus-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0007040-&&-lysosome organization|cellular_component-&-1&-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0034271-&&-phosphatidylinositol 3-kinase complex, class III, type I-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005768-&&-endosome-%%-GO:0035032-&&-phosphatidylinositol 3-kinase complex, class III-%%-GO:0030425-&&-dendrite-%%-GO:0034272-&&-phosphatidylinositol 3-kinase complex, class III, type II-%%-GO:0010008-&&-endosome membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:BECN1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	BECN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BECN1	0.41434913	0.07010403	69	4	FALSE	BECN1	BECN1	137.8208955	0	68	0	0.76442939	FALSE	1	BECN1	360178	0.03734784
789337	taxon:9606	2.50669608	1.05E-04	175710	1902	receptor interacting serine/threonine kinase 2	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070671-&&-response to interleukin-12-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0070673-&&-response to interleukin-18-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0042098-&&-T cell proliferation-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0033091-&&-positive regulation of immature T cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0007254-&&-JNK cascade-%%-GO:0071225-&&-cellular response to muramyl dipeptide-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0001961-&&-positive regulation of cytokine-mediated signaling pathway-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0071224-&&-cellular response to peptidoglycan-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0070427-&&-nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006954-&&-inflammatory response-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0045627-&&-positive regulation of T-helper 1 cell differentiation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0030274-&&-LIM domain binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0050700-&&-CARD domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004871-&&-signal transducer activity	G:9606:RIPK2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05131-&&-Shigellosis	RIPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK2	0.39893149	0.14608774	69	4	FALSE	RIPK2	RIPK2	132.4179105	0	68	0	0.74888399	FALSE	1	RIPK2	179326	0.04292255
789473	taxon:9606	2.41547188	2.19E-04	175390	1902	peroxiredoxin 6	gene	biological_process-&-1&-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0016042-&&-lipid catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051920-&&-peroxiredoxin activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PRDX6			KEGG-&-1&-hsa01100-&&-Metabolic pathways	PRDX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX6	0.41399778	0.09859792	69	4	FALSE	PRDX6	PRDX6	172.3731343	0	68	0	0.76408802	FALSE	1	PRDX6	346388	0.0469909
789539	taxon:9606	2.42051363	1.03E-04	175234	1902	squamous cell carcinoma antigen recognized by T-cells 3	gene	biological_process-&-1&-GO:0048872-&&-homeostasis of number of cells-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0000902-&&-cell morphogenesis-%%-GO:1903586-&&-positive regulation of histone deubiquitination|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005691-&&-U6atac snRNP-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071002-&&-U4atac/U6atac snRNP-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0071001-&&-U4/U6 snRNP-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0017070-&&-U6 snRNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030624-&&-U6atac snRNA binding	G:9606:SART3				SART3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SART3	0.41313546	0.12211669	69	4	FALSE	SART3	SART3	186.9701493	0	68	0	0.76324773	FALSE	1	SART3	209668	0.05125865
789857	taxon:9606	2.36206082	6.50E-04	174500	1902	cytoskeleton associated protein 4	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005856-&&-cytoskeleton-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0042599-&&-lamellar body-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:CKAP4			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	CKAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKAP4	0.42335912	0.07327001	69	4	FALSE	CKAP4	CKAP4	232.7313433	0	68	0	0.77298986	FALSE	1	CKAP4	925256	0.05822877
789881	taxon:9606	2.4825902	2.75E-04	174440	1902	TNFAIP3 interacting protein 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0006954-&&-inflammatory response-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0006412-&&-translation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0085032-&&-modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006952-&&-defense response-%%-GO:0009101-&&-glycoprotein biosynthetic process-%%-GO:0045071-&&-negative regulation of viral genome replication|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TNIP1				TNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNIP1	0.4028051	0.07281773	69	4	FALSE	TNIP1	TNIP1	113.0746269	0	68	0	0.75290163	FALSE	1	TNIP1	318214	0.03478601
790014	taxon:9606	2.32818654	3.40E-04	174096	1902	tubulin gamma complex associated protein 2	gene	biological_process-&-1&-GO:0007020-&&-microtubule nucleation-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051298-&&-centrosome duplication|cellular_component-&-1&-GO:0008275-&&-gamma-tubulin small complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005816-&&-spindle pole body-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0016020-&&-membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TUBGCP2				TUBGCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP2	0.42951885	0.14748508	69	4	FALSE	TUBGCP2	TUBGCP2	195.826087	0	69	0	0.77863558	FALSE	0	TUBGCP2	494536	0.04656366
790038	taxon:9606	2.52355444	1.29E-04	174037	1902	topoisomerase (DNA) II binding protein 1	gene	biological_process-&-1&-GO:0033314-&&-mitotic DNA replication checkpoint-%%-GO:0006281-&&-DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005694-&&-chromosome-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:TOPBP1			KEGG-&-1&-hsa03440-&&-Homologous recombination	TOPBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOPBP1	0.39626647	0.10085934	69	4	FALSE	TOPBP1	TOPBP1	162.5074627	0	68	0	0.74607426	FALSE	1	TOPBP1	227606	0.0538233
790158	taxon:9606	2.56010714	1.24E-04	173743	1902	centrosomal protein 152	gene	biological_process-&-1&-GO:0051298-&&-centrosome duplication-%%-GO:0098535-&&-de novo centriole assembly involved in multi-ciliated epithelial cell differentiation-%%-GO:0007099-&&-centriole replication-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0098536-&&-deuterosome-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CEP152				CEP152	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP152	0.39060865	0.10144928	69	4	FALSE	CEP152	CEP152	88.66666667	0	69	0	0.73998214	FALSE	0	CEP152	179196	0.03196669
790176	taxon:9606	2.41421144	1.19E-04	173708	1902	exportin 7	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005643-&&-nuclear pore-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005049-&&-nuclear export signal receptor activity	G:9606:XPO7				XPO7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO7	0.41421393	0.17647059	69	4	FALSE	XPO7	XPO7	177.6376812	0	69	0	0.76429809	FALSE	0	XPO7	262496	0.04822127
790348	taxon:9606	2.50701119	1.06E-04	173262	1902	inhibitor of Bruton tyrosine kinase	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030292-&&-protein tyrosine kinase inhibitor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:IBTK				IBTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IBTK	0.39888135	0.0877431	69	4	FALSE	IBTK	IBTK	136.6865672	0	68	0	0.74883147	FALSE	1	IBTK	204026	0.04396908
790349	taxon:9606	2.38632425	4.81E-04	173257	1902	golgi reassembly stacking protein 2	gene	biological_process-&-1&-GO:0006996-&&-organelle organization-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GORASP2				GORASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GORASP2	0.41905454	0.0400682	69	4	FALSE	GORASP2	GORASP2	121.1014493	0	69	0	0.76894596	FALSE	0	GORASP2	487386	0.03151173
790467	taxon:9606	2.34016071	0.00109526	172778	1902	adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1	gene	biological_process-&-1&-GO:0046324-&&-regulation of glucose import-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0090003-&&-regulation of establishment of protein localization to plasma membrane-%%-GO:0007165-&&-signal transduction-%%-GO:0007049-&&-cell cycle-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0016581-&&-NuRD complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0043422-&&-protein kinase B binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:APPL1	APPL1	TRUE	KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04211-&&-Longevity regulating pathway	APPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APPL1	0.42732108	0.06965174	69	4	FALSE	APPL1	APPL1	155.5522388	0	68	0	0.77663988	FALSE	1	APPL1	1055704	0.03754427
790914	taxon:9606	2.6615724	2.21E-04	170710	1902	ubiquitin fold modifier 1	gene	biological_process-&-1&-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071569-&&-protein ufmylation-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UFM1				UFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFM1	0.37571775	0.07161125	69	4	FALSE	UFM1	UFM1	76.85507246	0	69	0	0.72307127	FALSE	0	UFM1	256652	0.03559635
791283	taxon:9606	2.55742871	1.66E-04	169370	1902	centrosomal protein 126	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0097546-&&-ciliary base|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP126				CEP126	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP126	0.39101774	0.06095482	69	4	FALSE	CEP126	CEP126	94.11594203	0	69	0	0.74042855	FALSE	0	CEP126	228012	0.03362464
791390	taxon:9606	2.41625965	7.45E-05	168828	1902	RNA binding motif protein 25	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM25			KEGG-&-1&-hsa03040-&&-Spliceosome	RBM25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM25	0.41386281	0.23401535	69	4	FALSE	RBM25	RBM25	231.3768116	0	69	0	0.76395672	FALSE	0	RBM25	205994	0.06307588
787244	taxon:9606	2.39751063	2.06E-04	179810	1902	interferon regulatory factor 3	gene	biological_process-&-1&-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0071359-&&-cellular response to dsRNA-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0071888-&&-macrophage apoptotic process-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0039530-&&-MDA-5 signaling pathway-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0045351-&&-type I interferon biosynthetic process-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0006915-&&-apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:IRF3	IRF3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05133-&&-Pertussis	IRF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF3	0.4170993	0.1011655	68	4	FALSE	IRF3	IRF3	144.2878788	0	67	0	0.76708156	FALSE	1	IRF3	300898	0.0381432
787347	taxon:9606	2.3450449	1.07E-04	179612	1902	methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1	gene	biological_process-&-1&-GO:0009257-&&-10-formyltetrahydrofolate biosynthetic process-%%-GO:0009086-&&-methionine biosynthetic process-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0019346-&&-transsulfuration-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007507-&&-heart development-%%-GO:0006164-&&-purine nucleotide biosynthetic process-%%-GO:0001780-&&-neutrophil homeostasis-%%-GO:0009113-&&-purine nucleobase biosynthetic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0048703-&&-embryonic viscerocranium morphogenesis-%%-GO:0061053-&&-somite development-%%-GO:0009069-&&-serine family amino acid metabolic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0006555-&&-methionine metabolic process-%%-GO:0000105-&&-histidine biosynthetic process-%%-GO:0009070-&&-serine family amino acid biosynthetic process-%%-GO:0046655-&&-folic acid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004477-&&-methenyltetrahydrofolate cyclohydrolase activity-%%-GO:0004329-&&-formate-tetrahydrofolate ligase activity-%%-GO:0004488-&&-methylenetetrahydrofolate dehydrogenase (NADP+) activity-%%-GO:0004486-&&-methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity-%%-GO:0004487-&&-methylenetetrahydrofolate dehydrogenase (NAD+) activity-%%-GO:0005524-&&-ATP binding	G:9606:MTHFD1			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways	MTHFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFD1	0.42643107	0.15244755	68	4	FALSE	MTHFD1	MTHFD1	243.0757576	0	67	0	0.77582585	FALSE	1	MTHFD1	260998	0.05904894
788198	taxon:9606	2.4940917	1.31E-04	178098	1902	RB binding protein 5, histone lysine methyltransferase complex subunit	gene	biological_process-&-1&-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043627-&&-response to estrogen-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005730-&&-nucleolus-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:RBBP5			KEGG-&-1&-hsa04934-&&-Cushing syndrome	RBBP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP5	0.40094757	0.15337995	68	4	FALSE	RBBP5	RBBP5	135.5151515	0	67	0	0.75098472	FALSE	1	RBBP5	220576	0.04227296
788510	taxon:9606	2.48936505	6.24E-05	177531	1902	SON DNA binding protein	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008380-&&-RNA splicing-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0006397-&&-mRNA processing-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0050733-&&-RS domain binding-%%-GO:0005515-&&-protein binding	G:9606:SON				SON	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SON	0.40170886	0.24539069	68	4	FALSE	SON	SON	185.4117647	0	68	0	0.75177249	FALSE	0	SON	151920	0.05751857
788545	taxon:9606	2.60658579	2.05E-04	177461	1902	serum response factor	gene	biological_process-&-1&-GO:0048821-&&-erythrocyte development-%%-GO:1900222-&&-negative regulation of beta-amyloid clearance-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0001947-&&-heart looping-%%-GO:0003257-&&-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001666-&&-response to hypoxia-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030878-&&-thyroid gland development-%%-GO:0034097-&&-response to cytokine-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0009725-&&-response to hormone-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045214-&&-sarcomere organization-%%-GO:0051150-&&-regulation of smooth muscle cell differentiation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0048589-&&-developmental growth-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0010735-&&-positive regulation of transcription via serum response element binding-%%-GO:0033561-&&-regulation of water loss via skin-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0048538-&&-thymus development-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0010669-&&-epithelial structure maintenance-%%-GO:0007507-&&-heart development-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0061145-&&-lung smooth muscle development-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0030220-&&-platelet formation-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0060425-&&-lung morphogenesis-%%-GO:0022028-&&-tangential migration from the subventricular zone to the olfactory bulb-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060532-&&-bronchus cartilage development-%%-GO:0002011-&&-morphogenesis of an epithelial sheet-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090398-&&-cellular senescence-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0045059-&&-positive thymic T cell selection-%%-GO:0031175-&&-neuron projection development-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0060947-&&-cardiac vascular smooth muscle cell differentiation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0001707-&&-mesoderm formation-%%-GO:0008306-&&-associative learning-%%-GO:0048666-&&-neuron development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030168-&&-platelet activation-%%-GO:0007616-&&-long-term memory-%%-GO:0090009-&&-primitive streak formation-%%-GO:0009636-&&-response to toxic substance-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0046016-&&-positive regulation of transcription by glucose-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0060324-&&-face development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0010736-&&-serum response element binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0070878-&&-primary miRNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SRF			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRF	0.38364362	0.0951049	68	4	FALSE	SRF	SRF	94.68181818	0	67	0	0.7322357	FALSE	1	SRF	230688	0.03801885
788713	taxon:9606	2.35402552	1.34E-04	177133	1902	tropomyosin 4	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006936-&&-muscle contraction-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane-%%-GO:0005862-&&-muscle thin filament tropomyosin-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005509-&&-calcium ion binding	G:9606:TPM4			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TPM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPM4	0.42480423	0.15320457	68	4	FALSE	TPM4	TPM4	184.4558824	0	68	0	0.77432908	FALSE	0	TPM4	270796	0.04548884
788854	taxon:9606	2.35560107	1.90E-04	176750	1902	valyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006438-&&-valyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004832-&&-valine-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:VARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	VARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VARS	0.4245201	0.12028095	68	4	FALSE	VARS	VARS	210	0	68	0	0.77406649	FALSE	0	VARS	372148	0.05200061
789276	taxon:9606	2.46683473	3.38E-04	175840	1902	sorting nexin 3	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:2000642-&&-negative regulation of early endosome to late endosome transport-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0010324-&&-membrane invagination-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0009617-&&-response to bacterium-%%-GO:0022615-&&-protein to membrane docking-%%-GO:0051224-&&-negative regulation of protein transport-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0070676-&&-intralumenal vesicle formation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031901-&&-early endosome membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0032009-&&-early phagosome-%%-GO:0005829-&&-cytosol-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding	G:9606:SNX3			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX3	0.40537779	0.07769974	68	4	FALSE	SNX3	SNX3	132.3235294	0	68	0	0.75552755	FALSE	0	SNX3	419932	0.03953525
789367	taxon:9606	2.33905782	8.92E-05	175649	1902	BUB3, mitotic checkpoint protein	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0071173-&&-spindle assembly checkpoint-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BUB3			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	BUB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB3	0.42752257	0.19973661	68	4	FALSE	BUB3	BUB3	277.8235294	0	68	0	0.7768237	FALSE	0	BUB3	248758	0.06694543
789972	taxon:9606	2.5720813	1.56E-04	174215	1902	GABA type A receptor-associated protein	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0061024-&&-membrane organization-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0097225-&&-sperm midpiece-%%-GO:0005930-&&-axoneme-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005764-&&-lysosome-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005776-&&-autophagosome-%%-GO:0005829-&&-cytosol-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0050811-&&-GABA receptor binding	G:9606:GABARAP			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04136-&&-Autophagy - other	GABARAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAP	0.3887902	0.10722611	68	4	FALSE	GABARAP	GABARAP	84.90909091	0	67	0	0.73798645	FALSE	1	GABARAP	198796	0.03139049
790124	taxon:9606	2.43548133	6.49E-04	173820	1902	DEAD-box helicase 19B	gene	biological_process-&-1&-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:DDX19B				DDX19B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX19B	0.41059645	0.03467954	68	4	FALSE	DDX19B	DDX19B	105.0882353	0	68	0	0.76075311	FALSE	0	DDX19B	589764	0.02979634
790233	taxon:9606	2.62218371	2.37E-04	173563	1902	microtubule associated scaffold protein 2	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008017-&&-microtubule binding	G:9606:MTUS2				MTUS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTUS2	0.38136153	0.02703963	68	4	FALSE	MTUS2	MTUS2	73.21212121	0	67	0	0.72963605	FALSE	1	MTUS2	321932	0.0307513
790522	taxon:9606	2.5487632	2.44E-04	172613	1902	tubulin gamma complex associated protein 4	gene	biological_process-&-1&-GO:0006461-&&-protein complex assembly-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0051298-&&-centrosome duplication-%%-GO:0031122-&&-cytoplasmic microtubule organization|cellular_component-&-1&-GO:0005816-&&-spindle pole body-%%-GO:0005813-&&-centrosome-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0016020-&&-membrane-%%-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005874-&&-microtubule-%%-GO:0055037-&&-recycling endosome-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TUBGCP4				TUBGCP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBGCP4	0.39234716	0.14398595	68	4	FALSE	TUBGCP4	TUBGCP4	138.1323529	0	68	0	0.7418728	FALSE	0	TUBGCP4	406642	0.04875642
790737	taxon:9606	2.51063495	7.62E-05	171354	1902	ribosomal protein L26 like 1	gene	biological_process-&-1&-GO:0006412-&&-translation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0015934-&&-large ribosomal subunit|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL26L1			KEGG-&-1&-hsa03010-&&-Ribosome	RPL26L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL26L1	0.39830562	0.50834065	68	4	FALSE	RPL26L1	RPL26L1	207.7058824	0	68	0	0.74822751	FALSE	0	RPL26L1	130630	0.06716098
790890	taxon:9606	2.35512841	1.05E-04	170757	1902	RNA 2',3'-cyclic phosphate and 5'-OH ligase	gene	biological_process-&-1&-GO:0001890-&&-placenta development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation|cellular_component-&-1&-GO:0072669-&&-tRNA-splicing ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0003972-&&-RNA ligase (ATP) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:RTCB				RTCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RTCB	0.4246053	0.2594381	68	4	FALSE	RTCB	RTCB	271.5882353	0	68	0	0.77414527	FALSE	0	RTCB	222240	0.06717493
791102	taxon:9606	2.45360013	7.34E-05	170050	1902	BRX1, biogenesis of ribosomes	gene	biological_process-&-1&-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:BRIX1				BRIX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRIX1	0.40756437	0.29631255	68	4	FALSE	BRIX1	BRIX1	207.1176471	0	68	0	0.75773331	FALSE	0	BRIX1	162544	0.06000818
791454	taxon:9606	2.32991965	9.51E-05	168578	1902	AHNAK nucleoprotein	gene	biological_process-&-1&-GO:1901385-&&-regulation of voltage-gated calcium channel activity-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0043034-&&-costamere-%%-GO:0005634-&&-nucleus-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0030315-&&-T-tubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0097493-&&-structural molecule activity conferring elasticity	G:9606:AHNAK				AHNAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHNAK	0.42919935	0.1967366	68	4	FALSE	AHNAK	AHNAK	234.3030303	0	67	0	0.77834673	FALSE	1	AHNAK	229740	0.05568641
791503	taxon:9606	2.47360958	1.32E-04	168356	1902	ring finger and WD repeat domain 2	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010212-&&-response to ionizing radiation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RFWD2			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	RFWD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFWD2	0.40426752	0.17995338	68	4	FALSE	RFWD2	RFWD2	158.5909091	0	67	0	0.7543984	FALSE	1	RFWD2	218778	0.04777817
791855	taxon:9606	2.35276509	2.59E-04	182969	1902	acetyl-CoA carboxylase alpha	gene	biological_process-&-1&-GO:0001894-&&-tissue homeostasis-%%-GO:0006084-&&-acetyl-CoA metabolic process-%%-GO:0044268-&&-multicellular organismal protein metabolic process-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:2001295-&&-malonyl-CoA biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005739-&&-mitochondrion-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004075-&&-biotin carboxylase activity-%%-GO:0003989-&&-acetyl-CoA carboxylase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ACACA	ACACA	TRUE	KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism	ACACA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACACA	0.42503181	0.08516242	68	4	FALSE	ACACA	ACACA	190.1029412	0	68	0	0.77453915	FALSE	0	ACACA	429206	0.0469179
792168	taxon:9606	2.54813298	3.84E-04	182491	1902	Fas ligand	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0046666-&&-retinal cell programmed cell death-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0070266-&&-necroptotic process-%%-GO:0070848-&&-response to growth factor-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0048388-&&-endosomal lumen acidification-%%-GO:1903514-&&-calcium ion transport from endoplasmic reticulum to cytosol-%%-GO:0070231-&&-T cell apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006955-&&-immune response-%%-GO:0030644-&&-cellular chloride ion homeostasis-%%-GO:0006915-&&-apoptotic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006925-&&-inflammatory cell apoptotic process-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005901-&&-caveola-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0060205-&&-cytoplasmic vesicle lumen-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0005123-&&-death receptor binding	G:9606:FASLG	FASLG	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05330-&&-Allograft rejection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FASLG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASLG	0.3924442	0.07550483	68	4	FALSE	FASLG	FASLG	101.6470588	0	68	0	0.74197784	FALSE	0	FASLG	584566	0.03595698
792227	taxon:9606	2.36458169	2.29E-04	182380	1902	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2	gene	biological_process-&-1&-GO:0045822-&&-negative regulation of heart contraction-%%-GO:0033292-&&-T-tubule organization-%%-GO:0006984-&&-ER-nucleus signaling pathway-%%-GO:0032470-&&-positive regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1903515-&&-calcium ion transport from cytosol to endoplasmic reticulum-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0006996-&&-organelle organization-%%-GO:0070296-&&-sarcoplasmic reticulum calcium ion transport-%%-GO:0007155-&&-cell adhesion-%%-GO:0014883-&&-transition between fast and slow fiber-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0086036-&&-regulation of cardiac muscle cell membrane potential-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0008544-&&-epidermis development-%%-GO:1990036-&&-calcium ion import into sarcoplasmic reticulum-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:1903233-&&-regulation of calcium ion-dependent exocytosis of neurotransmitter|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0097470-&&-ribbon synapse-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0012506-&&-vesicle membrane|molecular_function-&-1&-GO:0031775-&&-lutropin-choriogonadotropic hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0086039-&&-calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential-%%-GO:0019899-&&-enzyme binding-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0044548-&&-S100 protein binding	G:9606:ATP2A2			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2A2	0.42290778	0.06899767	68	4	FALSE	ATP2A2	ATP2A2	195.6969697	0	67	0	0.77256972	FALSE	1	ATP2A2	500820	0.04905626
792608	taxon:9606	2.47487002	1.93E-04	181730	1902	dishevelled segment polarity protein 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0021915-&&-neural tube development-%%-GO:0048675-&&-axon extension-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0099054-&&-presynapse assembly-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0050821-&&-protein stabilization-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0007411-&&-axon guidance-%%-GO:0001505-&&-regulation of neurotransmitter levels-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0035176-&&-social behavior-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0022007-&&-convergent extension involved in neural plate elongation-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048668-&&-collateral sprouting-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0060134-&&-prepulse inhibition-%%-GO:1905386-&&-positive regulation of protein localization to presynapse-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0007507-&&-heart development-%%-GO:0043113-&&-receptor clustering-%%-GO:0050808-&&-synapse organization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0043197-&&-dendritic spine-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0043005-&&-neuron projection-%%-GO:0045202-&&-synapse-%%-GO:0014069-&&-postsynaptic density-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030136-&&-clathrin-coated vesicle|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0003674-&&-molecular_function-%%-GO:0008013-&&-beta-catenin binding	G:9606:DVL1	DVL1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DVL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DVL1	0.40406162	0.09184149	68	4	FALSE	DVL1	DVL1	123.3181818	0	67	0	0.75418833	FALSE	1	DVL1	266988	0.03734373
792970	taxon:9606	2.55538049	1.56E-04	181064	1902	forkhead box G1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007420-&&-brain development-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0048664-&&-neuron fate determination-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0021852-&&-pyramidal neuron migration-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXG1			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FOXG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXG1	0.39133115	0.04872695	68	4	FALSE	FOXG1	FOXG1	99.13235294	0	68	0	0.74076992	FALSE	0	FOXG1	234504	0.03538455
792972	taxon:9606	2.31636994	2.59E-04	181066	1902	FK506 binding protein 4	gene	biological_process-&-1&-GO:0046661-&&-male sex differentiation-%%-GO:0006457-&&-protein folding-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0006463-&&-steroid hormone receptor complex assembly-%%-GO:0031111-&&-negative regulation of microtubule polymerization or depolymerization-%%-GO:0031503-&&-protein complex localization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006825-&&-copper ion transport-%%-GO:0007566-&&-embryo implantation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0030850-&&-prostate gland development-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0044295-&&-axonal growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0032767-&&-copper-dependent protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0005524-&&-ATP binding	G:9606:FKBP4			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	FKBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP4	0.43170997	0.11655012	68	4	FALSE	FKBP4	FKBP4	197.030303	0	67	0	0.78060501	FALSE	1	FKBP4	397956	0.04573239
792980	taxon:9606	2.3530802	1.58E-04	181048	1902	forkhead box O3	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0001547-&&-antral ovarian follicle growth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0071386-&&-cellular response to corticosterone stimulus-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0001556-&&-oocyte maturation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0031667-&&-response to nutrient levels-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1904646-&&-cellular response to beta-amyloid-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:1901300-&&-positive regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0001544-&&-initiation of primordial ovarian follicle growth-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:1990785-&&-response to water-immersion restraint stress-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:FOXO3	FOXO3	TRUE	KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04137-&&-Mitophagy - animal	FOXO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO3	0.42497489	0.16549605	68	4	FALSE	FOXO3	FOXO3	197.4264706	0	68	0	0.77448663	FALSE	0	FOXO3	289218	0.0485674
793070	taxon:9606	2.50890184	1.27E-04	180811	1902	general transcription factor IIB	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:GTF2B			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis	GTF2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2B	0.39858076	0.13426573	68	4	FALSE	GTF2B	GTF2B	128.4848485	0	67	0	0.74851636	FALSE	1	GTF2B	200210	0.04142847
793214	taxon:9606	2.31636994	1.70E-04	180516	1902	heat shock protein family A (Hsp70) member 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007286-&&-spermatid development-%%-GO:0009409-&&-response to cold-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding-%%-GO:0007140-&&-male meiosis-%%-GO:0009408-&&-response to heat|cellular_component-&-1&-GO:0072687-&&-meiotic spindle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0036128-&&-CatSper complex-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:HSPA2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa03040-&&-Spliceosome-%%-hsa05164-&&-Influenza A-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA2	0.43170997	0.13915716	68	4	FALSE	HSPA2	HSPA2	195.3823529	0	68	0	0.78060501	FALSE	0	HSPA2	339730	0.04552963
793217	taxon:9606	2.37293209	9.80E-05	180513	1902	heat shock protein family A (Hsp70) member 6	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0070370-&&-cellular heat acclimation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0042026-&&-protein refolding|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042623-&&-ATPase activity, coupled	G:9606:HSPA6			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa03040-&&-Spliceosome-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04213-&&-Longevity regulating pathway - multiple species	HSPA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA6	0.42141956	0.14881475	68	4	FALSE	HSPA6	HSPA6	191.5441177	0	68	0	0.77117798	FALSE	0	HSPA6	246168	0.04859546
787205	taxon:9606	2.36269104	2.61E-04	179870	1902	microtubule associated protein 1B	gene	biological_process-&-1&-GO:0016358-&&-dendrite development-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0048675-&&-axon extension-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0032387-&&-negative regulation of intracellular transport-%%-GO:0061162-&&-establishment of monopolar cell polarity-%%-GO:0009987-&&-cellular process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:MAP1B				MAP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1B	0.4232462	0.09497965	67	4	FALSE	MAP1B	MAP1B	199.9253731	0	67	0	0.77288483	FALSE	0	MAP1B	418078	0.05001401
787794	taxon:9606	2.53348038	3.28E-04	178772	1902	protein kinase AMP-activated catalytic subunit alpha 2	gene	biological_process-&-1&-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0014850-&&-response to muscle activity-%%-GO:0016236-&&-macroautophagy-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0006950-&&-response to stress-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0050405-&&-[acetyl-CoA carboxylase] kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047322-&&-[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	G:9606:PRKAA2	PRKAA2	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	PRKAA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAA2	0.39471393	0.04794211	67	4	FALSE	PRKAA2	PRKAA2	87.65671642	0	67	0	0.74441994	FALSE	0	PRKAA2	357122	0.02970382
787800	taxon:9606	2.6451867	2.67E-04	178770	1902	protein kinase AMP-activated non-catalytic subunit beta 2	gene	biological_process-&-1&-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:PRKAB2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04921-&&-Oxytocin signaling pathway	PRKAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAB2	0.37804515	0.05192308	67	4	FALSE	PRKAB2	PRKAB2	69.16923077	0	66	0	0.72580222	FALSE	1	PRKAB2	279448	0.03093488
787885	taxon:9606	2.49566724	3.72E-05	178659	1902	proteasome subunit beta 6	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0045296-&&-cadherin binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB6			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB6	0.40069444	0.47263682	67	4	FALSE	PSMB6	PSMB6	169.0746269	0	67	0	0.75072213	FALSE	0	PSMB6	110328	0.05316812
788271	taxon:9606	2.38112494	1.41E-04	177965	1902	ribosomal protein S6 kinase B1	gene	biological_process-&-1&-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0007616-&&-long-term memory-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0007281-&&-germ cell development-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0048633-&&-positive regulation of skeletal muscle tissue growth-%%-GO:0032868-&&-response to insulin-%%-GO:0046324-&&-regulation of glucose import-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0045471-&&-response to ethanol-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0007584-&&-response to nutrient-%%-GO:0009749-&&-response to glucose-%%-GO:0043201-&&-response to leucine-%%-GO:0042493-&&-response to drug-%%-GO:0031929-&&-TOR signaling-%%-GO:0016477-&&-cell migration-%%-GO:0009408-&&-response to heat-%%-GO:0009611-&&-response to wounding-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0033574-&&-response to testosterone-%%-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0033762-&&-response to glucagon-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0009636-&&-response to toxic substance-%%-GO:0007568-&&-aging-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001662-&&-behavioral fear response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0016301-&&-kinase activity-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004711-&&-ribosomal protein S6 kinase activity	G:9606:RPS6KB1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04714-&&-Thermogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	RPS6KB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KB1	0.41996956	0.11586538	67	4	FALSE	RPS6KB1	RPS6KB1	153.0923077	0	66	0	0.76981251	FALSE	1	RPS6KB1	258072	0.03936151
788582	taxon:9606	2.35118954	1.68E-04	177396	1902	threonyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006412-&&-translation-%%-GO:0006435-&&-threonyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0004829-&&-threonine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	TARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARS	0.42531663	0.13613749	67	4	FALSE	TARS	TARS	230.2238806	0	67	0	0.77480174	FALSE	0	TARS	305956	0.05645144
788741	taxon:9606	2.55270206	2.53E-04	177058	1902	translin associated factor X	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0015031-&&-protein transport-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:TSNAX				TSNAX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSNAX	0.39174176	0.02451923	67	4	FALSE	TSNAX	TSNAX	87.12307692	0	66	0	0.74121632	FALSE	1	TSNAX	267078	0.0310778
788919	taxon:9606	2.53316527	2.56E-04	176596	1902	breast cancer anti-estrogen resistance 3	gene	biological_process-&-1&-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:BCAR3				BCAR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAR3	0.39476303	0.03075531	67	4	FALSE	BCAR3	BCAR3	101.2537313	0	67	0	0.74447245	FALSE	0	BCAR3	309786	0.03462461
789254	taxon:9606	2.37482275	7.19E-05	175888	1902	eukaryotic translation initiation factor 3 subunit D	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0002191-&&-cap-dependent translational initiation-%%-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation-%%-GO:0001732-&&-formation of cytoplasmic translation initiation complex|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0098808-&&-mRNA cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3D			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3D	0.42108406	0.21483492	67	4	FALSE	EIF3D	EIF3D	220.2089552	0	67	0	0.77086287	FALSE	0	EIF3D	195508	0.05621116
789430	taxon:9606	2.38427604	1.64E-04	175497	1902	cytoskeleton associated protein 5	gene	biological_process-&-1&-GO:0046785-&&-microtubule polymerization-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0030951-&&-establishment or maintenance of microtubule cytoskeleton polarity-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0050658-&&-RNA transport-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007051-&&-spindle organization-%%-GO:0051298-&&-centrosome duplication|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0000776-&&-kinetochore-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0051010-&&-microtubule plus-end binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CKAP5				CKAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKAP5	0.41941452	0.07259615	67	4	FALSE	CKAP5	CKAP5	198.5076923	0	66	0	0.76928733	FALSE	1	CKAP5	323844	0.05146026
789607	taxon:9606	2.36930833	3.25E-04	175067	1902	major vault protein	gene	biological_process-&-1&-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0051028-&&-mRNA transport-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0015031-&&-protein transport-%%-GO:0023057-&&-negative regulation of signaling-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MVP				MVP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MVP	0.4220641	0.06971154	67	4	FALSE	MVP	MVP	156.1076923	0	66	0	0.77178194	FALSE	1	MVP	453402	0.03941166
789712	taxon:9606	2.33858516	1.49E-04	174847	1902	dynactin subunit 2	gene	biological_process-&-1&-GO:0032402-&&-melanosome transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0008283-&&-cell proliferation-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005869-&&-dynactin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030286-&&-dynein complex-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0030507-&&-spectrin binding	G:9606:DCTN2			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05016-&&-Huntington disease	DCTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCTN2	0.42760897	0.13894231	67	4	FALSE	DCTN2	DCTN2	187.0923077	0	66	0	0.77690247	FALSE	1	DCTN2	264114	0.0449488
789807	taxon:9606	2.40712147	1.50E-04	174612	1902	ubiquitination factor E4B	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0008626-&&-granzyme-mediated apoptotic signaling pathway-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0031175-&&-neuron projection development-%%-GO:0009411-&&-response to UV-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0051117-&&-ATPase binding	G:9606:UBE4B			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE4B	0.41543396	0.13221154	67	4	FALSE	UBE4B	UBE4B	144.8923077	0	66	0	0.76547975	FALSE	1	UBE4B	258284	0.03890989
789820	taxon:9606	2.37104144	1.64E-04	174570	1902	PPARG coactivator 1 alpha	gene	biological_process-&-1&-GO:0008209-&&-androgen metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904635-&&-positive regulation of glomerular visceral epithelial cell apoptotic process-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0071250-&&-cellular response to nitrite-%%-GO:2000272-&&-negative regulation of receptor activity-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060612-&&-adipose tissue development-%%-GO:1901558-&&-response to metformin-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1904639-&&-cellular response to resveratrol-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0007623-&&-circadian rhythm-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006397-&&-mRNA processing-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0045333-&&-cellular respiration-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:1901863-&&-positive regulation of muscle tissue development-%%-GO:0002931-&&-response to ischemia-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0046321-&&-positive regulation of fatty acid oxidation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:1901860-&&-positive regulation of mitochondrial DNA metabolic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0042594-&&-response to starvation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0000422-&&-mitophagy-%%-GO:0071871-&&-response to epinephrine-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:2000184-&&-positive regulation of progesterone biosynthetic process-%%-GO:0006012-&&-galactose metabolic process-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0090258-&&-negative regulation of mitochondrial fission-%%-GO:0071313-&&-cellular response to caffeine-%%-GO:0043201-&&-response to leucine-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0009409-&&-response to cold-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0051552-&&-flavone metabolic process-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0002021-&&-response to dietary excess-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0071332-&&-cellular response to fructose stimulus-%%-GO:1901857-&&-positive regulation of cellular respiration-%%-GO:0021549-&&-cerebellum development-%%-GO:0050821-&&-protein stabilization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2000507-&&-positive regulation of energy homeostasis-%%-GO:0030900-&&-forebrain development-%%-GO:0006461-&&-protein complex assembly-%%-GO:0071873-&&-response to norepinephrine-%%-GO:0042493-&&-response to drug-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:0014850-&&-response to muscle activity-%%-GO:1904640-&&-response to methionine-%%-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0035865-&&-cellular response to potassium ion-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007568-&&-aging-%%-GO:0007586-&&-digestion-%%-GO:1990845-&&-adaptive thermogenesis-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0097440-&&-apical dendrite-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1990843-&&-subsarcolemmal mitochondrion-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0016605-&&-PML body-%%-GO:1990844-&&-interfibrillar mitochondrion|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0050681-&&-androgen receptor binding	G:9606:PPARGC1A	PPARGC1A	TRUE	KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa05016-&&-Huntington disease-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	PPARGC1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARGC1A	0.4217556	0.15829941	67	4	FALSE	PPARGC1A	PPARGC1A	167.1791045	0	67	0	0.77149309	FALSE	0	PPARGC1A	284144	0.04226277
789887	taxon:9606	2.3962502	1.58E-04	174424	1902	structural maintenance of chromosomes 2	gene	biological_process-&-1&-GO:0051383-&&-kinetochore organization-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0045132-&&-meiotic chromosome segregation-%%-GO:0010032-&&-meiotic chromosome condensation-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0000796-&&-condensin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:SMC2				SMC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC2	0.41731869	0.11080959	67	4	FALSE	SMC2	SMC2	173.7313433	0	67	0	0.76729163	FALSE	0	SMC2	321038	0.04571509
789910	taxon:9606	2.31195841	7.87E-05	174380	1902	insulin like growth factor 2 mRNA binding protein 1	gene	biological_process-&-1&-GO:0070934-&&-CRD-mediated mRNA stabilization-%%-GO:0051028-&&-mRNA transport-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0010610-&&-regulation of mRNA stability involved in response to stress-%%-GO:0022013-&&-pallium cell proliferation in forebrain-%%-GO:0010467-&&-gene expression-%%-GO:0042035-&&-regulation of cytokine biosynthetic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030424-&&-axon-%%-GO:0070937-&&-CRD-mediated mRNA stability complex-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045182-&&-translation regulator activity	G:9606:IGF2BP1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	IGF2BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2BP1	0.43253373	0.16372682	67	4	FALSE	IGF2BP1	IGF2BP1	277.2835821	0	67	0	0.78134027	FALSE	0	IGF2BP1	257044	0.06422716
789943	taxon:9606	2.40270994	1.37E-04	174294	1902	nucleoporin 50	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:NUP50			KEGG-&-1&-hsa03013-&&-RNA transport	NUP50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP50	0.41619672	0.08955224	67	4	FALSE	NUP50	NUP50	145.9402985	0	67	0	0.76621501	FALSE	0	NUP50	235302	0.03879168
790339	taxon:9606	2.61729951	2.08E-04	173290	1902	paroxysmal nonkinesigenic dyskinesia	gene	biological_process-&-1&-GO:0019243-&&-methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione-%%-GO:0050884-&&-neuromuscular process controlling posture-%%-GO:0046929-&&-negative regulation of neurotransmitter secretion-%%-GO:0032225-&&-regulation of synaptic transmission, dopaminergic-%%-GO:0042053-&&-regulation of dopamine metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004416-&&-hydroxyacylglutathione hydrolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PNKD				PNKD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNKD	0.3820732	0.01447309	67	4	FALSE	PNKD	PNKD	57.53731343	0	67	0	0.73045008	FALSE	0	PNKD	195720	0.02390812
790367	taxon:9606	2.46037498	4.00E-04	173205	1902	mitogen-activated protein kinase 8 interacting protein 2	gene	biological_process-&-1&-GO:0007172-&&-signal complex assembly-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0046958-&&-nonassociative learning-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0007254-&&-JNK cascade-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0001662-&&-behavioral fear response-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0007617-&&-mating behavior-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0035176-&&-social behavior|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019894-&&-kinesin binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0032403-&&-protein complex binding	G:9606:MAPK8IP2			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAPK8IP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8IP2	0.40644211	0.05	67	4	FALSE	MAPK8IP2	MAPK8IP2	101.1846154	0	66	0	0.75660417	FALSE	1	MAPK8IP2	378274	0.02992493
790445	taxon:9606	2.48873484	3.45E-04	172842	1902	tuftelin interacting protein 11	gene	biological_process-&-1&-GO:0031214-&&-biomineral tissue development-%%-GO:0006396-&&-RNA processing-%%-GO:0031848-&&-protection from non-homologous end joining at telomere-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0000390-&&-spliceosomal complex disassembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1904876-&&-negative regulation of DNA ligase activity-%%-GO:2001033-&&-negative regulation of double-strand break repair via nonhomologous end joining|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0071008-&&-U2-type post-mRNA release spliceosomal complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TFIP11				TFIP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFIP11	0.40181058	0.04703754	67	4	FALSE	TFIP11	TFIP11	111.1044776	0	67	0	0.75187753	FALSE	0	TFIP11	397106	0.03443176
790932	taxon:9606	2.46982827	5.17E-05	170674	1902	splicing factor 3b subunit 6	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0001825-&&-blastocyst formation|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0005686-&&-U2 snRNP-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005684-&&-U2-type spliceosomal complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SF3B6			KEGG-&-1&-hsa03040-&&-Spliceosome	SF3B6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SF3B6	0.40488645	0.27403846	67	4	FALSE	SF3B6	SF3B6	193.9846154	0	66	0	0.75502862	FALSE	1	SF3B6	125168	0.05810942
791126	taxon:9606	2.41878053	3.63E-04	169952	1902	erbb2 interacting protein	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070433-&&-negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045175-&&-basal protein localization-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0006605-&&-protein targeting-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005604-&&-basement membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005176-&&-ErbB-2 class receptor binding	G:9606:ERBIN			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	ERBIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBIN	0.41343147	0.08317308	67	4	FALSE	ERBIN	ERBIN	131.1384615	0	66	0	0.76353658	FALSE	1	ERBIN	388148	0.03587918
791696	taxon:9606	2.55317473	1.46E-04	167391	1902	SET domain containing lysine methyltransferase 7	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045471-&&-response to ethanol-%%-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:0051570-&&-regulation of histone H3-K9 methylation-%%-GO:0018027-&&-peptidyl-lysine dimethylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070828-&&-heterochromatin organization-%%-GO:0006325-&&-chromatin organization-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity	G:9606:SETD7			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa00310-&&-Lysine degradation	SETD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETD7	0.39166924	0.22259615	67	4	FALSE	SETD7	SETD7	202.5538462	0	66	0	0.74113755	FALSE	1	SETD7	276488	0.07153574
792207	taxon:9606	2.412951	1.45E-04	182419	1902	asparagine synthetase (glutamine-hydrolyzing)	gene	biological_process-&-1&-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0009416-&&-response to light stimulus-%%-GO:0032354-&&-response to follicle-stimulating hormone-%%-GO:0070981-&&-L-asparagine biosynthetic process-%%-GO:0043200-&&-response to amino acid-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006529-&&-asparagine biosynthetic process-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0031427-&&-response to methotrexate-%%-GO:0042149-&&-cellular response to glucose starvation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004066-&&-asparagine synthase (glutamine-hydrolyzing) activity-%%-GO:0005515-&&-protein binding-%%-GO:0048037-&&-cofactor binding	G:9606:ASNS			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	ASNS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASNS	0.4144303	0.12483039	67	4	FALSE	ASNS	ASNS	157.5223881	0	67	0	0.76450817	FALSE	0	ASNS	245606	0.04266587
792564	taxon:9606	2.43043958	1.40E-04	181810	1902	Cbl proto-oncogene B	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0006607-&&-NLS-bearing protein import into nucleus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CBLB			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	CBLB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBLB	0.4114482	0.20240385	67	4	FALSE	CBLB	CBLB	154.7076923	0	66	0	0.7615934	FALSE	1	CBLB	233462	0.04333118
792623	taxon:9606	2.42208918	1.92E-04	181703	1902	enoyl-CoA hydratase, short chain 1	gene	biological_process-&-1&-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding	G:9606:ECHS1			KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	ECHS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECHS1	0.41286671	0.08173077	67	4	FALSE	ECHS1	ECHS1	152.8	0	66	0	0.76298514	FALSE	1	ECHS1	290696	0.04209031
792858	taxon:9606	2.46699228	5.14E-05	181263	1902	ERCC excision repair 6, chromatin remodeling factor	gene	biological_process-&-1&-GO:0045494-&&-photoreceptor cell maintenance-%%-GO:0006284-&&-base-excision repair-%%-GO:0007256-&&-activation of JNKK activity-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0009636-&&-response to toxic substance-%%-GO:0009411-&&-response to UV-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000303-&&-response to superoxide-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0010224-&&-response to UV-B-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010165-&&-response to X-ray-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding	G:9606:ERCC6			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	ERCC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC6	0.4053519	0.28493894	67	4	FALSE	ERCC6	ERCC6	244.0149254	0	67	0	0.75550129	FALSE	0	ERCC6	155750	0.07253714
792926	taxon:9606	2.44398929	1.42E-04	181132	1902	cyclin G associated kinase	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:1905224-&&-clathrin-coated pit assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0072318-&&-clathrin coat disassembly-%%-GO:0007049-&&-cell cycle-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0007030-&&-Golgi organization-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0090160-&&-Golgi to lysosome transport-%%-GO:0051085-&&-chaperone mediated protein folding requiring cofactor-%%-GO:0072600-&&-establishment of protein localization to Golgi-%%-GO:0016191-&&-synaptic vesicle uncoating-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007029-&&-endoplasmic reticulum organization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0030332-&&-cyclin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:GAK				GAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAK	0.4091671	0.1275441	67	4	FALSE	GAK	GAK	120.119403	0	67	0	0.75933512	FALSE	0	GAK	216636	0.03441948
792965	taxon:9606	2.53332283	2.89E-04	181078	1902	four and a half LIM domains 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0001725-&&-stress fiber-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:FHL3				FHL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHL3	0.39473848	0.04855769	67	4	FALSE	FHL3	FHL3	92.18461538	0	66	0	0.7444462	FALSE	1	FHL3	299996	0.03151314
792978	taxon:9606	2.47691823	1.45E-04	181052	1902	forkhead box M1	gene	biological_process-&-1&-GO:0090344-&&-negative regulation of cell aging-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:2000781-&&-positive regulation of double-strand break repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0071156-&&-regulation of cell cycle arrest|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXM1			KEGG-&-1&-hsa04218-&&-Cellular senescence	FOXM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXM1	0.4037275	0.0737223	67	4	FALSE	FOXM1	FOXM1	132.4328358	0	67	0	0.75384696	FALSE	0	FOXM1	234860	0.04027352
793289	taxon:9606	2.25476603	5.52E-04	180368	1902	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005740-&&-mitochondrial envelope-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016509-&&-long-chain-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0003988-&&-acetyl-CoA C-acyltransferase activity-%%-GO:0003723-&&-RNA binding	G:9606:HADHB			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	HADHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HADHB	0.443505	0.11080959	67	4	FALSE	HADHB	HADHB	229.8059702	0	67	0	0.79087233	FALSE	0	HADHB	643158	0.04914452
787159	taxon:9606	2.4362691	0.00117922	179955	1902	LDL receptor related protein 1	gene	biological_process-&-1&-GO:0032374-&&-regulation of cholesterol transport-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0032370-&&-positive regulation of lipid transport-%%-GO:0007568-&&-aging-%%-GO:0008283-&&-cell proliferation-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0051222-&&-positive regulation of protein transport-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0032429-&&-regulation of phospholipase A2 activity-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0097242-&&-beta-amyloid clearance-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005730-&&-nucleolus-%%-GO:0043235-&&-receptor complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0042954-&&-lipoprotein transporter activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0070325-&&-lipoprotein particle receptor binding-%%-GO:0004872-&&-receptor activity	G:9606:LRP1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa05010-&&-Alzheimer disease-%%-hsa05144-&&-Malaria	LRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRP1	0.41046369	0.05109127	66	4	FALSE	LRP1	LRP1	106.15625	0	65	0	0.76062182	FALSE	1	LRP1	1150256	0.03011743
787402	taxon:9606	2.43343312	5.95E-05	179488	1902	nucleosome assembly protein 1 like 4	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:NAP1L4				NAP1L4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAP1L4	0.41094205	0.17956349	66	4	FALSE	NAP1L4	NAP1L4	215.625	0	65	0	0.76109448	FALSE	1	NAP1L4	171954	0.06021363
787802	taxon:9606	2.42382228	1.92E-04	162380	1902	forkhead box K1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0007517-&&-muscle organ development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FOXK1				FOXK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXK1	0.4125715	0.09417249	66	4	FALSE	FOXK1	FOXK1	131.8787879	0	66	0	0.76269629	FALSE	0	FOXK1	263432	0.03615835
787901	taxon:9606	2.52056089	9.41E-05	178642	1902	proteasome 26S subunit, non-ATPase 5	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070682-&&-proteasome regulatory particle assembly-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process|cellular_component-&-1&-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0022624-&&-proteasome accessory complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PSMD5				PSMD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD5	0.39673709	0.34685315	66	4	FALSE	PSMD5	PSMD5	124.0909091	0	66	0	0.74657318	FALSE	0	PSMD5	147360	0.04130441
787974	taxon:9606	2.42933669	8.25E-05	178482	1902	phosphoenolpyruvate carboxykinase 1	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0071332-&&-cellular response to fructose stimulus-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0046327-&&-glycerol biosynthetic process from pyruvate-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0032868-&&-response to insulin-%%-GO:1904640-&&-response to methionine-%%-GO:0070741-&&-response to interleukin-6-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0051365-&&-cellular response to potassium ion starvation-%%-GO:0007568-&&-aging-%%-GO:0061402-&&-positive regulation of transcription from RNA polymerase II promoter in response to acidic pH-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006107-&&-oxaloacetate metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004613-&&-phosphoenolpyruvate carboxykinase (GTP) activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031406-&&-carboxylic acid binding-%%-GO:0019003-&&-GDP binding	G:9606:PCK1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03320-&&-PPAR signaling pathway	PCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCK1	0.411635	0.12121212	66	4	FALSE	PCK1	PCK1	160.0151515	0	66	0	0.76177722	FALSE	0	PCK1	177620	0.04478011
788634	taxon:9606	2.53804947	1.19E-04	177282	1902	transcription factor AP-4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:TFAP4			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	TFAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAP4	0.39400335	0.09230769	66	4	FALSE	TFAP4	TFAP4	119.8787879	0	66	0	0.74365842	FALSE	0	TFAP4	191214	0.04087963
788647	taxon:9606	2.3067591	3.96E-04	177252	1902	transferrin receptor	gene	biological_process-&-1&-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0061024-&&-membrane organization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0031623-&&-receptor internalization-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0033572-&&-transferrin transport-%%-GO:0045830-&&-positive regulation of isotype switching-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0097286-&&-iron ion import-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045780-&&-positive regulation of bone resorption|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:1990712-&&-HFE-transferrin receptor complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0016020-&&-membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004998-&&-transferrin receptor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0033570-&&-transferrin transmembrane transporter activity	G:9606:TFRC			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04145-&&-Phagosome-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04216-&&-Ferroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	TFRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFRC	0.43350864	0.08630952	66	4	FALSE	TFRC	TFRC	234.34375	0	65	0	0.78220682	FALSE	1	TFRC	603134	0.05399954
788809	taxon:9606	2.47219159	2.49E-04	176834	1902	tyrosine kinase 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0005131-&&-growth hormone receptor binding	G:9606:TYK2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	TYK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYK2	0.40449939	0.11061508	66	4	FALSE	TYK2	TYK2	133.78125	0	65	0	0.75463474	FALSE	1	TYK2	398402	0.0404548
788893	taxon:9606	2.40995746	2.15E-04	176661	1902	X-ray repair cross complementing 1	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0010033-&&-response to organic substance-%%-GO:0061819-&&-telomeric DNA-containing double minutes formation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006288-&&-base-excision repair, DNA ligation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000012-&&-single strand break repair-%%-GO:0042493-&&-response to drug-%%-GO:1905765-&&-negative regulation of protection from non-homologous end joining at telomere-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0070522-&&-ERCC4-ERCC1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:1990599-&&-3' overhang single-stranded DNA endodeoxyribonuclease activity	G:9606:XRCC1			KEGG-&-1&-hsa03410-&&-Base excision repair	XRCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRCC1	0.41494508	0.11188811	66	4	FALSE	XRCC1	XRCC1	171.7424242	0	66	0	0.76500709	FALSE	0	XRCC1	343494	0.04632537
789027	taxon:9606	2.44146841	4.56E-05	176347	1902	RNA binding motif protein 10	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006397-&&-mRNA processing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:RBM10				RBM10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM10	0.40958957	0.22371032	66	4	FALSE	RBM10	RBM10	240.109375	0	65	0	0.75975526	FALSE	1	RBM10	153732	0.06820845
789064	taxon:9606	2.58232236	5.95E-05	176259	1902	barrier to autointegration factor 1	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0009615-&&-response to virus-%%-GO:0051169-&&-nuclear transport-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0015074-&&-DNA integration|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0097726-&&-LEM domain binding	G:9606:BANF1				BANF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BANF1	0.38724832	0.19642857	66	4	FALSE	BANF1	BANF1	165.296875	0	65	0	0.73627961	FALSE	1	BANF1	142618	0.06212392
789111	taxon:9606	2.49440681	2.68E-04	176173	1902	B-cell CLL/lymphoma 10	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0042226-&&-interleukin-6 biosynthetic process-%%-GO:0009620-&&-response to fungus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032094-&&-response to food-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0002250-&&-adaptive immune response-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0050856-&&-regulation of T cell receptor signaling pathway-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032765-&&-positive regulation of mast cell cytokine production-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051259-&&-protein oligomerization-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008219-&&-cell death-%%-GO:0042109-&&-lymphotoxin A biosynthetic process-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0006968-&&-cellular defense response-%%-GO:0045087-&&-innate immune response-%%-GO:0002906-&&-negative regulation of mature B cell apoptotic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0070231-&&-T cell apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0032449-&&-CBM complex-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019209-&&-kinase activator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0043621-&&-protein self-association	G:9606:BCL10			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	BCL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL10	0.40089692	0.10565476	66	4	FALSE	BCL10	BCL10	129.671875	0	65	0	0.7509322	FALSE	1	BCL10	356564	0.04103916
789300	taxon:9606	2.75500236	8.11E-05	175795	1902	mediator complex subunit 26	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:MED26				MED26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED26	0.3629761	0.25128205	66	4	FALSE	MED26	MED26	65.46969697	0	66	0	0.70749961	FALSE	0	MED26	96250	0.04027972
789335	taxon:9606	2.5041752	1.83E-04	175708	1902	Fas associated via death domain	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2000454-&&-positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0048535-&&-lymph node development-%%-GO:0070236-&&-negative regulation of activation-induced cell death of T cells-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0071550-&&-death-inducing signaling complex assembly-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:0036462-&&-TRAIL-activated apoptotic signaling pathway-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0048538-&&-thymus development-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097049-&&-motor neuron apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0043278-&&-response to morphine-%%-GO:0048536-&&-spleen development-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0097342-&&-ripoptosome|molecular_function-&-1&-GO:0032813-&&-tumor necrosis factor receptor superfamily binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0033612-&&-receptor serine/threonine kinase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0089720-&&-caspase binding	G:9606:FADD			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	FADD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FADD	0.39933308	0.12103175	66	4	FALSE	FADD	FADD	103.921875	0	65	0	0.74930413	FALSE	1	FADD	233538	0.03329893
789743	taxon:9606	2.40538837	1.70E-04	174783	1902	ubiquitin like modifier activating enzyme 2	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031510-&&-SUMO activating enzyme complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019948-&&-SUMO activating enzyme activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:UBA2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA2	0.41573328	0.11282051	66	4	FALSE	UBA2	UBA2	150.969697	0	66	0	0.7657686	FALSE	0	UBA2	255868	0.0404338
789746	taxon:9606	2.40491571	1.54E-04	174773	1902	ARP3 actin related protein 3 homolog	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0016344-&&-meiotic chromosome movement towards spindle pole-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051653-&&-spindle localization-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0060271-&&-cilium assembly-%%-GO:0033206-&&-meiotic cytokinesis|cellular_component-&-1&-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016020-&&-membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005903-&&-brush border|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:ACTR3			KEGG-&-1&-hsa04530-&&-Tight junction	ACTR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTR3	0.41581499	0.18414918	66	4	FALSE	ACTR3	ACTR3	180.1060606	0	66	0	0.76584738	FALSE	0	ACTR3	276516	0.04824294
789913	taxon:9606	2.36773279	7.19E-05	174379	1902	insulin like growth factor 2 mRNA binding protein 3	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0010467-&&-gene expression-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0042035-&&-regulation of cytokine biosynthetic process-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:IGF2BP3				IGF2BP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2BP3	0.42234496	0.28018648	66	4	FALSE	IGF2BP3	IGF2BP3	248.8181818	0	66	0	0.77204454	FALSE	0	IGF2BP3	180076	0.06265501
790072	taxon:9606	2.47833622	3.58E-04	173941	1902	Ras association domain family member 1	gene	biological_process-&-1&-GO:0007050-&&-cell cycle arrest-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:RASSF1	RASSF1	TRUE	KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05200-&&-Pathways in cancer	RASSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF1	0.4034965	0.09176587	66	4	FALSE	RASSF1	RASSF1	127.734375	0	65	0	0.75361063	FALSE	1	RASSF1	422000	0.03900038
790205	taxon:9606	2.59681739	7.51E-05	173637	1902	PHD finger protein 8	gene	biological_process-&-1&-GO:0061188-&&-negative regulation of chromatin silencing at rDNA-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0007420-&&-brain development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071557-&&-histone H3-K27 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0035574-&&-histone H4-K20 demethylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070544-&&-histone H3-K36 demethylation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0035064-&&-methylated histone binding-%%-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0035575-&&-histone demethylase activity (H4-K20 specific)-%%-GO:0071558-&&-histone demethylase activity (H3-K27 specific)-%%-GO:0008270-&&-zinc ion binding	G:9606:PHF8				PHF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF8	0.38508676	0.20839161	66	4	FALSE	PHF8	PHF8	176.7727273	0	66	0	0.73386377	FALSE	0	PHF8	175330	0.06887267
790820	taxon:9606	2.57050575	2.15E-04	171097	1902	intersectin 2	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0006897-&&-endocytosis-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:ITSN2				ITSN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITSN2	0.3890285	0.03621032	66	4	FALSE	ITSN2	ITSN2	83.3125	0	65	0	0.73824904	FALSE	1	ITSN2	228282	0.03062799
790917	taxon:9606	2.40696392	1.18E-04	170700	1902	tripartite motif containing 33	gene	biological_process-&-1&-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070412-&&-R-SMAD binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:TRIM33				TRIM33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM33	0.41546115	0.14781746	66	4	FALSE	TRIM33	TRIM33	203.5625	0	65	0	0.76550601	FALSE	1	TRIM33	266554	0.0544014
790997	taxon:9606	2.40570348	1.84E-04	170463	1902	centrosomal protein 55	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006997-&&-nucleus organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005886-&&-plasma membrane-%%-GO:0005814-&&-centriole-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP55				CEP55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP55	0.41567883	0.1155754	66	4	FALSE	CEP55	CEP55	150.921875	0	65	0	0.76571609	FALSE	1	CEP55	278070	0.04041901
791174	taxon:9606	2.33385852	1.40E-04	169826	1902	importin 9	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:IPO9				IPO9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO9	0.42847499	0.12307692	66	4	FALSE	IPO9	IPO9	192.969697	0	66	0	0.77769025	FALSE	0	IPO9	300008	0.0461026
791435	taxon:9606	2.42004096	1.59E-04	168660	1902	WNK lysine deficient protein kinase 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0023016-&&-signal transduction by trans-phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0090188-&&-negative regulation of pancreatic juice secretion-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0006811-&&-ion transport-%%-GO:0050794-&&-regulation of cellular process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0003084-&&-positive regulation of systemic arterial blood pressure-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0048666-&&-neuron development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019869-&&-chloride channel inhibitor activity	G:9606:WNK1				WNK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNK1	0.41321615	0.1046627	66	4	FALSE	WNK1	WNK1	145.890625	0	65	0	0.76332651	FALSE	1	WNK1	255560	0.04003826
791577	taxon:9606	2.53426816	1.23E-04	167943	1902	centrosomal protein 290	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0030902-&&-hindbrain development-%%-GO:0060271-&&-cilium assembly-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0048793-&&-pronephros development-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0035580-&&-specific granule lumen-%%-GO:0036038-&&-MKS complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0034451-&&-centriolar satellite-%%-GO:0005814-&&-centriole-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP290				CEP290	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP290	0.39459123	0.1048951	66	4	FALSE	CEP290	CEP290	106.8636364	0	66	0	0.74428864	FALSE	0	CEP290	187382	0.03627509
791793	taxon:9606	2.55254451	1.86E-04	166851	1902	WD repeat domain 83	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0010008-&&-endosome membrane-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR83				WDR83	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR83	0.39176594	0.07925408	66	5	FALSE	WDR83	WDR83	110.7575758	0	66	0	0.74124258	FALSE	0	WDR83	244448	0.03927234
791909	taxon:9606	2.35733417	1.56E-04	182889	1902	adenosylhomocysteinase	gene	biological_process-&-1&-GO:0019510-&&-S-adenosylhomocysteine catabolic process-%%-GO:0071268-&&-homocysteine biosynthetic process-%%-GO:0042745-&&-circadian sleep/wake cycle-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0002439-&&-chronic inflammatory response to antigenic stimulus-%%-GO:0007584-&&-response to nutrient-%%-GO:0000096-&&-sulfur amino acid metabolic process-%%-GO:0032259-&&-methylation-%%-GO:0033353-&&-S-adenosylmethionine cycle-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0030554-&&-adenyl nucleotide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004013-&&-adenosylhomocysteinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0051287-&&-NAD binding	G:9606:AHCY			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways	AHCY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHCY	0.42420799	0.12003968	66	4	FALSE	AHCY	AHCY	228.5	0	65	0	0.77377764	FALSE	1	AHCY	296376	0.05657434
791933	taxon:9606	2.51756735	2.25E-04	182854	1902	anaplastic lymphoma receptor tyrosine kinase	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0021766-&&-hippocampus development-%%-GO:0036269-&&-swimming behavior-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway-%%-GO:0048666-&&-neuron development-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0030534-&&-adult behavior-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0016310-&&-phosphorylation-%%-GO:0090648-&&-response to environmental enrichment-%%-GO:0000187-&&-activation of MAPK activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ALK			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa05200-&&-Pathways in cancer	ALK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALK	0.39720884	0.09077381	66	4	FALSE	ALK	ALK	118.78125	0	65	0	0.74707211	FALSE	1	ALK	260146	0.03926415
791970	taxon:9606	2.41547188	1.38E-04	182784	1902	amyloid beta precursor protein binding family B member 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0050760-&&-negative regulation of thymidylate synthase biosynthetic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010039-&&-response to iron ion-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0007409-&&-axonogenesis-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006302-&&-double-strand break repair-%%-GO:0045739-&&-positive regulation of DNA repair|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:1990761-&&-growth cone lamellipodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0016607-&&-nuclear speck-%%-GO:0044304-&&-main axon-%%-GO:0005634-&&-nucleus-%%-GO:0030426-&&-growth cone-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0043234-&&-protein complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0045202-&&-synapse-%%-GO:1990812-&&-growth cone filopodium-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0042393-&&-histone binding	G:9606:APBB1			KEGG-&-1&-hsa05010-&&-Alzheimer disease	APBB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBB1	0.41399778	0.11210317	66	4	FALSE	APBB1	APBB1	154.46875	0	65	0	0.76408802	FALSE	1	APBB1	236686	0.04198953
792225	taxon:9606	2.46242319	2.19E-04	182387	1902	ATPase Na+/K+ transporting subunit beta 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:0050821-&&-protein stabilization-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:1903281-&&-positive regulation of calcium:sodium antiporter activity-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0010107-&&-potassium ion import-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0007155-&&-cell adhesion-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:0046034-&&-ATP metabolic process-%%-GO:1903288-&&-positive regulation of potassium ion import-%%-GO:0044861-&&-protein transport into plasma membrane raft-%%-GO:1903278-&&-positive regulation of sodium ion export from cell-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0001666-&&-response to hypoxia-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0042383-&&-sarcolemma-%%-GO:0005901-&&-caveola-%%-GO:0016020-&&-membrane-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0014704-&&-intercalated disc-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0031402-&&-sodium ion binding-%%-GO:0030955-&&-potassium ion binding-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0008144-&&-drug binding	G:9606:ATP1B1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04978-&&-Mineral absorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04976-&&-Bile secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1B1	0.40610404	0.08717949	66	4	FALSE	ATP1B1	ATP1B1	122.8636364	0	66	0	0.7562628	FALSE	0	ATP1B1	288060	0.03627764
792574	taxon:9606	2.4394202	1.10E-04	181789	1902	cyclin E1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0000723-&&-telomere maintenance-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007129-&&-synapsis-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0051726-&&-regulation of cell cycle|cellular_component-&-1&-GO:0097134-&&-cyclin E1-CDK2 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity	G:9606:CCNE1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05162-&&-Measles-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer	CCNE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNE1	0.40993348	0.14871795	66	4	FALSE	CCNE1	CCNE1	153.0151515	0	66	0	0.76009663	FALSE	0	CCNE1	191658	0.0433305
792728	taxon:9606	2.46841027	5.42E-04	181490	1902	discs large MAGUK scaffold protein 4	gene	biological_process-&-1&-GO:0071625-&&-vocalization behavior-%%-GO:0007612-&&-learning-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0097120-&&-receptor localization to synapse-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0035176-&&-social behavior-%%-GO:0006461-&&-protein complex assembly-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0046710-&&-GDP metabolic process-%%-GO:2000821-&&-regulation of grooming behavior-%%-GO:0097113-&&-AMPA glutamate receptor clustering-%%-GO:0007268-&&-chemical synaptic transmission|cellular_component-&-1&-GO:0030863-&&-cortical cytoskeleton-%%-GO:0044306-&&-neuron projection terminus-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0030054-&&-cell junction-%%-GO:0098839-&&-postsynaptic density membrane-%%-GO:0044300-&&-cerebellar mossy fiber-%%-GO:0005829-&&-cytosol-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0045202-&&-synapse-%%-GO:0043197-&&-dendritic spine-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0044309-&&-neuron spine-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0044224-&&-juxtaparanode region of axon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0060076-&&-excitatory synapse-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0031812-&&-P2Y1 nucleotide receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0033130-&&-acetylcholine receptor binding-%%-GO:0097109-&&-neuroligin family protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0031697-&&-beta-1 adrenergic receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019900-&&-kinase binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0015276-&&-ligand-gated ion channel activity	G:9606:DLG4			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05016-&&-Huntington disease-%%-hsa05030-&&-Cocaine addiction	DLG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLG4	0.40511904	0.08184524	66	4	FALSE	DLG4	DLG4	104.859375	0	65	0	0.75526495	FALSE	1	DLG4	507478	0.0314233
787473	taxon:9606	2.45549078	2.19E-04	179361	1902	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0033033-&&-negative regulation of myeloid cell apoptotic process-%%-GO:0061081-&&-positive regulation of myeloid leukocyte cytokine production involved in immune response-%%-GO:0050900-&&-leukocyte migration-%%-GO:0019752-&&-carboxylic acid metabolic process-%%-GO:0010739-&&-positive regulation of protein kinase A signaling-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0007569-&&-cell aging-%%-GO:0043030-&&-regulation of macrophage activation-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:2000343-&&-positive regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0002906-&&-negative regulation of mature B cell apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0061078-&&-positive regulation of prostaglandin secretion involved in immune response-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0090344-&&-negative regulation of cell aging-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0090238-&&-positive regulation of arachidonic acid secretion-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005126-&&-cytokine receptor binding-%%-GO:0004167-&&-dopachrome isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0050178-&&-phenylpyruvate tautomerase activity	G:9606:MIF	MIF	TRUE	KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa00360-&&-Phenylalanine metabolism	MIF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MIF	0.40725056	0.11827957	65	4	FALSE	MIF	MIF	169.7142857	0	64	0	0.7574182	FALSE	1	MIF	329720	0.04963976
787775	taxon:9606	2.49740035	2.69E-04	178800	1902	protein phosphatase 3 catalytic subunit alpha	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0035690-&&-cellular response to drug-%%-GO:0051592-&&-response to calcium ion-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006816-&&-calcium ion transport-%%-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0001975-&&-response to amphetamine-%%-GO:1903244-&&-positive regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0042110-&&-T cell activation-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0033555-&&-multicellular organismal response to stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0014883-&&-transition between fast and slow fiber-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:1905205-&&-positive regulation of connective tissue replacement-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0048741-&&-skeletal muscle fiber development|cellular_component-&-1&-GO:0005955-&&-calcineurin complex-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse-%%-GO:0042383-&&-sarcolemma-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008144-&&-drug binding-%%-GO:0033192-&&-calmodulin-dependent protein phosphatase activity	G:9606:PPP3CA	PPP3CA	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3CA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3CA	0.40041638	0.05529954	65	4	FALSE	PPP3CA	PPP3CA	101.1428571	0	64	0	0.75043328	FALSE	1	PPP3CA	300488	0.03197709
787890	taxon:9606	2.66283283	7.20E-05	178655	1902	proteasome subunit beta 9	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:2000116-&&-regulation of cysteine-type endopeptidase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1990111-&&-spermatoproteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB9			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB9	0.37553991	0.40757808	65	4	FALSE	PSMB9	PSMB9	103.5873016	0	64	0	0.72286119	FALSE	1	PSMB9	96218	0.0480387
788217	taxon:9606	2.41562943	2.39E-04	178057	1902	ret proto-oncogene	gene	biological_process-&-1&-GO:1903263-&&-positive regulation of serine phosphorylation of STAT3 protein-%%-GO:0042551-&&-neuron maturation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001838-&&-embryonic epithelial tube formation-%%-GO:0007158-&&-neuron cell-cell adhesion-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0033619-&&-membrane protein proteolysis-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0007497-&&-posterior midgut development-%%-GO:0048265-&&-response to pain-%%-GO:0097021-&&-lymphocyte migration into lymphoid organs-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0072300-&&-positive regulation of metanephric glomerulus development-%%-GO:0035799-&&-ureter maturation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0061146-&&-Peyer's patch morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0060384-&&-innervation-%%-GO:0048484-&&-enteric nervous system development-%%-GO:0007411-&&-axon guidance-%%-GO:0001657-&&-ureteric bud development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0043235-&&-receptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0010008-&&-endosome membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005769-&&-early endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:RET			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	RET	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RET	0.41397078	0.14336918	65	4	FALSE	RET	RET	194.5079365	0	64	0	0.76406176	FALSE	1	RET	421014	0.05311822
788244	taxon:9606	2.53615882	2.67E-04	178015	1902	siah E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006915-&&-apoptotic process-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007411-&&-axon guidance-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding	G:9606:SIAH2				SIAH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIAH2	0.39429707	0.06554019	65	4	FALSE	SIAH2	SIAH2	100.6666667	0	64	0	0.74397353	FALSE	1	SIAH2	312200	0.03440058
788529	taxon:9606	2.50165432	1.55E-04	177496	1902	thyroid hormone receptor beta	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0060509-&&-Type I pneumocyte differentiation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008050-&&-female courtship behavior-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0007621-&&-negative regulation of female receptivity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070324-&&-thyroid hormone binding	G:9606:THRB			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	THRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRB	0.39973548	0.124936	65	4	FALSE	THRB	THRB	129.6031746	0	64	0	0.74972428	FALSE	1	THRB	239636	0.04113081
788623	taxon:9606	2.44272885	8.70E-05	177289	1902	telomerase reverse transcriptase	gene	biological_process-&-1&-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:1903704-&&-negative regulation of production of siRNA involved in RNA interference-%%-GO:0001172-&&-transcription, RNA-templated-%%-GO:0022616-&&-DNA strand elongation-%%-GO:0090399-&&-replicative senescence-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0006278-&&-RNA-dependent DNA biosynthetic process-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1903620-&&-positive regulation of transdifferentiation-%%-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0007004-&&-telomere maintenance via telomerase-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:0007005-&&-mitochondrion organization-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0032774-&&-RNA biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0042635-&&-positive regulation of hair cycle|cellular_component-&-1&-GO:1990572-&&-TERT-RMRP complex-%%-GO:0000333-&&-telomerase catalytic core complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0031379-&&-RNA-directed RNA polymerase complex-%%-GO:0000783-&&-nuclear telomere cap complex-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0003721-&&-telomerase RNA reverse transcriptase activity-%%-GO:0016779-&&-nucleotidyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003968-&&-RNA-directed 5'-3' RNA polymerase activity-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0003720-&&-telomerase activity-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003964-&&-RNA-directed DNA polymerase activity-%%-GO:0000049-&&-tRNA binding	G:9606:TERT			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer-%%-hsa05165-&&-Human papillomavirus infection	TERT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TERT	0.40937822	0.11674347	65	4	FALSE	TERT	TERT	165.1587302	0	64	0	0.75954519	FALSE	1	TERT	164646	0.04713873
788851	taxon:9606	2.41090279	2.67E-04	176749	1902	vasodilator-stimulated phosphoprotein	gene	biological_process-&-1&-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0001843-&&-neural tube closure-%%-GO:0034329-&&-cell junction assembly-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0031258-&&-lamellipodium membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005522-&&-profilin binding	G:9606:VASP			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04611-&&-Platelet activation-%%-hsa04530-&&-Tight junction-%%-hsa04022-&&-cGMP-PKG signaling pathway	VASP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VASP	0.41478238	0.09165387	65	4	FALSE	VASP	VASP	154.0476191	0	64	0	0.76484954	FALSE	1	VASP	345478	0.04167204
788948	taxon:9606	2.44225618	1.84E-04	176551	1902	O-linked N-acetylglucosamine (GlcNAc) transferase	gene	biological_process-&-1&-GO:0090526-&&-regulation of gluconeogenesis involved in cellular glucose homeostasis-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0032868-&&-response to insulin-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0007165-&&-signal transduction-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007584-&&-response to nutrient-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0000123-&&-histone acetyltransferase complex|molecular_function-&-1&-GO:0016262-&&-protein N-acetylglucosaminyltransferase activity-%%-GO:0008375-&&-acetylglucosaminyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0097363-&&-protein O-GlcNAc transferase activity-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)	G:9606:OGT			KEGG-&-1&-hsa04931-&&-Insulin resistance-%%-hsa00514-&&-Other types of O-glycan biosynthesis	OGT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OGT	0.40945745	0.08448541	65	4	FALSE	OGT	OGT	136.4444444	0	64	0	0.75962397	FALSE	1	OGT	263312	0.0387997
789152	taxon:9606	2.42980936	1.77E-04	176092	1902	protein inhibitor of activated STAT 2	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061665-&&-SUMO ligase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PIAS2			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	PIAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS2	0.41155492	0.1172555	65	4	FALSE	PIAS2	PIAS2	143.2380952	0	64	0	0.76169844	FALSE	1	PIAS2	260820	0.03992599
789253	taxon:9606	2.43784465	6.94E-05	175889	1902	eukaryotic translation initiation factor 3 subunit C	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:EIF3C			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3C	0.41019841	0.22115385	65	4	FALSE	EIF3C	EIF3C	188.2769231	0	65	0	0.76035922	FALSE	0	EIF3C	165390	0.05319625
789256	taxon:9606	2.43532378	5.47E-05	175890	1902	eukaryotic translation initiation factor 3 subunit B	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation-%%-GO:0075522-&&-IRES-dependent viral translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0003723-&&-RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:EIF3B			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3B	0.41062302	0.21923077	65	4	FALSE	EIF3B	EIF3B	198.9076923	0	65	0	0.76077937	FALSE	0	EIF3B	150572	0.05622038
789269	taxon:9606	2.50133922	2.42E-04	175861	1902	cell division cycle 23	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007091-&&-metaphase/anaphase transition of mitotic cell cycle-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:CDC23			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC23	0.39978584	0.11827957	65	4	FALSE	CDC23	CDC23	115	0	64	0	0.7497768	FALSE	1	CDC23	297572	0.03660553
789454	taxon:9606	2.5456121	3.40E-04	175438	1902	BCL2 associated athanogene 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:1903215-&&-negative regulation of protein targeting to mitochondrion-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0097178-&&-ruffle assembly-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0090367-&&-negative regulation of mRNA modification-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2001145-&&-negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:BAG4			KEGG-&-1&-hsa04668-&&-TNF signaling pathway	BAG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG4	0.39283283	0.09038462	65	4	FALSE	BAG4	BAG4	128.6153846	0	65	0	0.74239798	FALSE	0	BAG4	405504	0.04524281
789704	taxon:9606	2.30297778	1.56E-04	174858	1902	importin 7	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0007165-&&-signal transduction-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046332-&&-SMAD binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0042393-&&-histone binding	G:9606:IPO7				IPO7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO7	0.43422043	0.14759615	65	4	FALSE	IPO7	IPO7	242.5692308	0	65	0	0.78283704	FALSE	0	IPO7	345334	0.05530183
789872	taxon:9606	2.64818024	1.90E-04	174470	1902	coiled-coil domain containing 85B	gene	biological_process-&-1&-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC85B				CCDC85B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC85B	0.3776178	0.03509615	65	4	FALSE	CCDC85B	CCDC85B	66.52307692	0	65	0	0.72530329	FALSE	0	CCDC85B	210858	0.02984712
790028	taxon:9606	2.63352765	1.50E-04	174062	1902	midline 2	gene	biological_process-&-1&-GO:0010508-&&-positive regulation of autophagy-%%-GO:0045087-&&-innate immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0046597-&&-negative regulation of viral entry into host cell|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MID2				MID2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MID2	0.37971882	0.08192524	65	4	FALSE	MID2	MID2	87.63492063	0	64	0	0.72774539	FALSE	1	MID2	196698	0.03755207
790030	taxon:9606	2.4512368	5.14E-05	174058	1902	adhesion regulating molecule 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043248-&&-proteasome assembly-%%-GO:0010950-&&-positive regulation of endopeptidase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0008541-&&-proteasome regulatory particle, lid subcomplex-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0061133-&&-endopeptidase activator activity-%%-GO:0070628-&&-proteasome binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:ADRM1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa03050-&&-Proteasome	ADRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRM1	0.40795732	0.48413462	65	4	FALSE	ADRM1	ADRM1	157.9846154	0	65	0	0.7581272	FALSE	0	ADRM1	125532	0.0457484
790083	taxon:9606	2.36347881	1.42E-04	173917	1902	DEAD-box helicase 20	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006396-&&-RNA processing-%%-GO:0051170-&&-nuclear import-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050810-&&-regulation of steroid biosynthetic process-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0000244-&&-spliceosomal tri-snRNP complex assembly-%%-GO:0048477-&&-oogenesis-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0090571-&&-RNA polymerase II transcription repressor complex-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:DDX20			KEGG-&-1&-hsa03013-&&-RNA transport	DDX20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX20	0.42310513	0.15719406	65	4	FALSE	DDX20	DDX20	186.2539683	0	64	0	0.77275353	FALSE	1	DDX20	288122	0.04652463
790368	taxon:9606	2.46746494	1.73E-04	173204	1902	RNA binding protein, fox-1 homolog 2	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0021942-&&-radial glia guided migration of Purkinje cell-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0008380-&&-RNA splicing-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBFOX2				RBFOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBFOX2	0.40527425	0.1203277	65	4	FALSE	RBFOX2	RBFOX2	155.5714286	0	64	0	0.75542251	FALSE	1	RBFOX2	270224	0.04641116
790692	taxon:9606	2.48904994	7.11E-05	171460	1902	tropomodulin 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0048821-&&-erythrocyte development-%%-GO:1901992-&&-positive regulation of mitotic cell cycle phase transition-%%-GO:0051694-&&-pointed-end actin filament capping-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005865-&&-striated muscle thin filament-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005523-&&-tropomyosin binding	G:9606:TMOD3				TMOD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMOD3	0.40175972	0.18942308	65	4	FALSE	TMOD3	TMOD3	210.6153846	0	65	0	0.75182501	FALSE	0	TMOD3	201640	0.06536313
790921	taxon:9606	2.34614779	1.28E-04	170699	1902	serrate, RNA effector molecule	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008283-&&-cell proliferation-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0031053-&&-primary miRNA processing-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:SRRT				SRRT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRRT	0.42623061	0.14615385	65	4	FALSE	SRRT	SRRT	215	0	65	0	0.77564204	FALSE	0	SRRT	240316	0.05223144
791272	taxon:9606	2.53741925	1.53E-04	169417	1902	mitochondrial antiviral signaling protein	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0007165-&&-signal transduction-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0039529-&&-RIG-I signaling pathway-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0071651-&&-positive regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071660-&&-positive regulation of IP-10 production-%%-GO:0051607-&&-defense response to virus-%%-GO:1900063-&&-regulation of peroxisome organization-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0050700-&&-CARD domain binding	G:9606:MAVS			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B	MAVS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAVS	0.39410121	0.11776754	65	4	FALSE	MAVS	MAVS	111.4920635	0	64	0	0.74376346	FALSE	1	MAVS	200350	0.03843142
791329	taxon:9606	2.45202458	2.36E-04	169132	1902	reticulon 4	gene	biological_process-&-1&-GO:0007413-&&-axonal fasciculation-%%-GO:0071786-&&-endoplasmic reticulum tubular network organization-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0071787-&&-endoplasmic reticulum tubular network formation-%%-GO:0006915-&&-apoptotic process-%%-GO:0021801-&&-cerebral cortex radial glia guided migration-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000172-&&-regulation of branching morphogenesis of a nerve|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:RTN4			KEGG-&-1&-hsa05010-&&-Alzheimer disease	RTN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RTN4	0.40782625	0.06502816	65	4	FALSE	RTN4	RTN4	139.2698413	0	64	0	0.7579959	FALSE	1	RTN4	318294	0.04041074
791332	taxon:9606	2.56499133	1.96E-04	169117	1902	tripartite motif containing 54	gene	biological_process-&-1&-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0007165-&&-signal transduction-%%-GO:0055001-&&-muscle cell development-%%-GO:0007017-&&-microtubule-based process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM54				TRIM54	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM54	0.38986486	0.04710701	65	4	FALSE	TRIM54	TRIM54	88.14285714	0	64	0	0.73916811	FALSE	1	TRIM54	222132	0.03204094
791802	taxon:9606	2.81345518	9.80E-05	166799	1902	chromosome 15 open reading frame 48	gene	biological_process-&-1&-GO:1902600-&&-hydrogen ion transmembrane transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005751-&&-mitochondrial respiratory chain complex IV|molecular_function-&-1&-GO:0004129-&&-cytochrome-c oxidase activity	G:9606:C15orf48				C15orf48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C15orf48	0.35543484	0.11730769	65	4	FALSE	C15orf48	C15orf48	45.52307692	0	65	0	0.69775747	FALSE	0	C15orf48	124670	0.03712402
791819	taxon:9606	2.53568615	1.65E-04	166710	1902	tripartite motif containing 63	gene	biological_process-&-1&-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0007165-&&-signal transduction-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0031432-&&-titin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0004871-&&-signal transducer activity	G:9606:TRIM63				TRIM63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM63	0.39437057	0.07526882	65	4	FALSE	TRIM63	TRIM63	98.22222222	0	64	0	0.74405231	FALSE	1	TRIM63	207500	0.0336384
791917	taxon:9606	2.36962344	3.34E-04	182877	1902	AKT serine/threonine kinase 2	gene	biological_process-&-1&-GO:0032287-&&-peripheral nervous system myelin maintenance-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0008643-&&-carbohydrate transport-%%-GO:0065002-&&-intracellular protein transmembrane transport-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0071486-&&-cellular response to high light intensity-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0097473-&&-retinal rod cell apoptotic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0006417-&&-regulation of translation-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0007165-&&-signal transduction-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:AKT2	AKT2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	AKT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT2	0.42200798	0.11623144	65	4	FALSE	AKT2	AKT2	184.1428571	0	64	0	0.77172943	FALSE	1	AKT2	480904	0.0464495
792607	taxon:9606	2.48589885	1.47E-04	181731	1902	deoxyuridine triphosphatase	gene	biological_process-&-1&-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0046080-&&-dUTP metabolic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0006260-&&-DNA replication-%%-GO:0006226-&&-dUMP biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004170-&&-dUTP diphosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:DUT			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	DUT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUT	0.40226898	0.13056836	65	4	FALSE	DUT	DUT	134.7460318	0	64	0	0.75235019	FALSE	1	DUT	218862	0.04156076
792734	taxon:9606	2.44903104	1.89E-04	181477	1902	dynamin 1	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0061025-&&-membrane fusion-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051932-&&-synaptic transmission, GABAergic-%%-GO:0000266-&&-mitochondrial fission-%%-GO:1901998-&&-toxin transport-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006897-&&-endocytosis-%%-GO:0016185-&&-synaptic vesicle budding from presynaptic endocytic zone membrane-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007032-&&-endosome organization-%%-GO:0051262-&&-protein tetramerization-%%-GO:1903423-&&-positive regulation of synaptic vesicle recycling|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0043196-&&-varicosity-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030117-&&-membrane coat-%%-GO:0001917-&&-photoreceptor inner segment|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0031749-&&-D2 dopamine receptor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003924-&&-GTPase activity	G:9606:DNM1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04721-&&-Synaptic vesicle cycle	DNM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM1	0.40832476	0.07834101	65	4	FALSE	DNM1	DNM1	130.8888889	0	64	0	0.75849483	FALSE	1	DNM1	289614	0.0379222
792797	taxon:9606	2.42461005	1.59E-04	181352	1902	eukaryotic translation initiation factor 4E	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006417-&&-regulation of translation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006413-&&-translational initiation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0001662-&&-behavioral fear response-%%-GO:0030324-&&-lung development-%%-GO:0016032-&&-viral process-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0033391-&&-chromatoid body-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005845-&&-mRNA cap binding complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031370-&&-eukaryotic initiation factor 4G binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0019899-&&-enzyme binding	G:9606:EIF4E			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	EIF4E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4E	0.41243746	0.10650282	65	4	FALSE	EIF4E	EIF4E	140.5238095	0	64	0	0.76256499	FALSE	1	EIF4E	226172	0.03891506
792816	taxon:9606	2.41389633	1.57E-04	181323	1902	microtubule affinity regulating kinase 2	gene	biological_process-&-1&-GO:0030010-&&-establishment of cell polarity-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0001764-&&-neuron migration-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0000422-&&-mitophagy-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0051646-&&-mitochondrion localization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005884-&&-actin filament-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0097427-&&-microtubule bundle-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030295-&&-protein kinase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0050321-&&-tau-protein kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:MARK2				MARK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARK2	0.414268	0.13620072	65	4	FALSE	MARK2	MARK2	164.8412698	0	64	0	0.76435061	FALSE	1	MARK2	250154	0.04461465
792976	taxon:9606	2.48763195	3.57E-05	164672	1902	splicing regulatory glutamic acid and lysine rich protein 1	gene	biological_process-&-1&-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SREK1				SREK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREK1	0.40198873	0.22478239	65	4	FALSE	SREK1	SREK1	179.7619048	0	64	0	0.75206134	FALSE	1	SREK1	87722	0.05551634
792979	taxon:9606	2.40979991	2.77E-04	181049	1902	forkhead box O1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001568-&&-blood vessel development-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:1902617-&&-response to fluoride-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0070417-&&-cellular response to cold-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0006473-&&-protein acetylation-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0006914-&&-autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035947-&&-regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter-%%-GO:2000177-&&-regulation of neural precursor cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0070166-&&-enamel mineralization-%%-GO:0071549-&&-cellular response to dexamethasone stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:FOXO1	FOXO1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence	FOXO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO1	0.41497221	0.14900154	65	4	FALSE	FOXO1	FOXO1	169.2380952	0	64	0	0.76503335	FALSE	1	FOXO1	339866	0.04560336
787216	taxon:9606	2.52355444	2.16E-04	179849	1902	myelin basic protein	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007417-&&-central nervous system development-%%-GO:0061024-&&-membrane organization-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006955-&&-immune response-%%-GO:0008366-&&-axon ensheathment-%%-GO:0042552-&&-myelination-%%-GO:0009636-&&-response to toxic substance|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus-%%-GO:0033269-&&-internode region of axon-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0019911-&&-structural constituent of myelin sheath-%%-GO:0005515-&&-protein binding	G:9606:MBP				MBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBP	0.39626647	0.06150794	64	4	FALSE	MBP	MBP	105.703125	0	64	0	0.74607426	FALSE	0	MBP	262032	0.03538003
787709	taxon:9606	2.43170002	3.76E-04	178905	1902	phospholipid scramblase 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006915-&&-apoptotic process-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0006659-&&-phosphatidylserine biosynthetic process-%%-GO:0006953-&&-acute-phase response-%%-GO:0033003-&&-regulation of mast cell activation-%%-GO:0051607-&&-defense response to virus-%%-GO:0060368-&&-regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0030168-&&-platelet activation-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0017121-&&-phospholipid scrambling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0017128-&&-phospholipid scramblase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0042609-&&-CD4 receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:PLSCR1				PLSCR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLSCR1	0.41123494	0.06944444	64	4	FALSE	PLSCR1	PLSCR1	116.671875	0	64	0	0.76138333	FALSE	0	PLSCR1	406430	0.03275629
787772	taxon:9606	2.44493461	9.88E-05	178807	1902	protein phosphatase, Mg2+/Mn2+ dependent 1B	gene	biological_process-&-1&-GO:0006499-&&-N-terminal protein myristoylation-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0050687-&&-negative regulation of defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:PPM1B			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PPM1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1B	0.40900889	0.0952381	64	4	FALSE	PPM1B	PPM1B	198.84375	0	64	0	0.75917756	FALSE	0	PPM1B	235924	0.05698556
788379	taxon:9606	2.45107925	1.63E-04	177778	1902	signal sequence receptor subunit 1	gene	biological_process-&-1&-GO:0006613-&&-cotranslational protein targeting to membrane-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SSR1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSR1	0.40798354	0.14434524	64	4	FALSE	SSR1	SSR1	169.59375	0	64	0	0.75815346	FALSE	0	SSR1	266282	0.04903485
788631	taxon:9606	2.46525918	2.17E-04	177281	1902	transcription factor CP2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TFCP2				TFCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFCP2	0.40563686	0.04865151	64	4	FALSE	TFCP2	TFCP2	123.2419355	0	63	0	0.75579014	FALSE	1	TFCP2	280226	0.03661194
789067	taxon:9606	2.73814401	1.51E-04	159865	1902	keratin associated protein 10-9	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP10-9				KRTAP10-9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-9	0.36521089	0.18297197	64	4	FALSE	KRTAP10-9	KRTAP10-9	56.17741935	0	63	0	0.71030933	FALSE	1	KRTAP10-9	290758	0.03337933
789073	taxon:9606	2.73814401	1.51E-04	159863	1902	keratin associated protein 10-11	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP10-11				KRTAP10-11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP10-11	0.36521089	0.18297197	64	4	FALSE	KRTAP10-11	KRTAP10-11	56.17741935	0	63	0	0.71030933	FALSE	1	KRTAP10-11	290758	0.03337933
789332	taxon:9606	2.43075469	2.09E-04	175712	1902	TNF receptor superfamily member 14	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0031295-&&-T cell costimulation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0006954-&&-inflammatory response-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0002741-&&-positive regulation of cytokine secretion involved in immune response-%%-GO:0046642-&&-negative regulation of alpha-beta T cell proliferation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TNFRSF14			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF14	0.41139487	0.04653622	64	4	FALSE	TNFRSF14	TNFRSF14	130.1612903	0	63	0	0.76154089	FALSE	1	TNFRSF14	265112	0.03653979
789336	taxon:9606	2.43327556	2.20E-04	175711	1902	RAB11A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0032402-&&-melanosome transport-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:1990182-&&-exosomal secretion-%%-GO:0072594-&&-establishment of protein localization to organelle-%%-GO:0051650-&&-establishment of vesicle localization-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0000910-&&-cytokinesis-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0051223-&&-regulation of protein transport-%%-GO:0010796-&&-regulation of multivesicular body size-%%-GO:0098887-&&-neurotransmitter receptor transport, endosome to postsynaptic membrane-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0090150-&&-establishment of protein localization to membrane-%%-GO:0031175-&&-neuron projection development-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0072659-&&-protein localization to plasma membrane|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005828-&&-kinetochore microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005771-&&-multivesicular body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0030424-&&-axon-%%-GO:0000922-&&-spindle pole-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0008017-&&-microtubule binding	G:9606:RAB11A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04972-&&-Pancreatic secretion	RAB11A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB11A	0.41096866	0.09677419	64	4	FALSE	RAB11A	RAB11A	143.7903226	0	63	0	0.76112074	FALSE	1	RAB11A	306960	0.04037695
789507	taxon:9606	2.37687096	1.50E-04	175309	1902	nucleoporin 93	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090521-&&-glomerular visceral epithelial cell migration-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0072001-&&-renal system development-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0016925-&&-protein sumoylation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017056-&&-structural constituent of nuclear pore	G:9606:NUP93			KEGG-&-1&-hsa03013-&&-RNA transport	NUP93	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP93	0.4207212	0.09722222	64	4	FALSE	NUP93	NUP93	228.625	0	64	0	0.77052151	FALSE	0	NUP93	340240	0.05825421
789791	taxon:9606	2.47455491	3.25E-04	174671	1902	DExD-box helicase 39A	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding	G:9606:DDX39A				DDX39A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX39A	0.40411308	0.06716023	64	4	FALSE	DDX39A	DDX39A	135.9193548	0	63	0	0.75424085	FALSE	1	DDX39A	390666	0.04107436
789793	taxon:9606	2.53363794	2.09E-04	174658	1902	perilipin 3	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005811-&&-lipid particle-%%-GO:0010008-&&-endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PLIN3	PLIN3	TRUE		PLIN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLIN3	0.39468938	0.07667901	64	4	FALSE	PLIN3	PLIN3	102.483871	0	63	0	0.74439368	FALSE	1	PLIN3	248774	0.03476727
789963	taxon:9606	2.41657476	1.50E-04	174234	1902	Parkinsonism associated deglycase	gene	biological_process-&-1&-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0006508-&&-proteolysis-%%-GO:0036531-&&-glutathione deglycation-%%-GO:2000157-&&-negative regulation of ubiquitin-specific protease activity-%%-GO:0050821-&&-protein stabilization-%%-GO:0036527-&&-peptidyl-arginine deglycation-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0006914-&&-autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:2000277-&&-positive regulation of oxidative phosphorylation uncoupler activity-%%-GO:0036528-&&-peptidyl-lysine deglycation-%%-GO:1903094-&&-negative regulation of protein K48-linked deubiquitination-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0009438-&&-methylglyoxal metabolic process-%%-GO:1902903-&&-regulation of supramolecular fiber organization-%%-GO:0006517-&&-protein deglycosylation-%%-GO:2000825-&&-positive regulation of androgen receptor activity-%%-GO:0002866-&&-positive regulation of acute inflammatory response to antigenic stimulus-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0036529-&&-protein deglycation, glyoxal removal-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1903073-&&-negative regulation of death-inducing signaling complex assembly-%%-GO:1903122-&&-negative regulation of TRAIL-activated apoptotic signaling pathway-%%-GO:1903181-&&-positive regulation of dopamine biosynthetic process-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0018323-&&-enzyme active site formation via L-cysteine sulfinic acid-%%-GO:1901671-&&-positive regulation of superoxide dismutase activity-%%-GO:0050787-&&-detoxification of mercury ion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051899-&&-membrane depolarization-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0045560-&&-regulation of TRAIL receptor biosynthetic process-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:1903202-&&-negative regulation of oxidative stress-induced cell death-%%-GO:0036530-&&-protein deglycation, methylglyoxal removal-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:1903377-&&-negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:1902958-&&-positive regulation of mitochondrial electron transport, NADH to ubiquinone-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0036471-&&-cellular response to glyoxal-%%-GO:0046295-&&-glycolate biosynthetic process-%%-GO:1903200-&&-positive regulation of L-dopa decarboxylase activity-%%-GO:1905259-&&-negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903189-&&-glyoxal metabolic process-%%-GO:1903178-&&-positive regulation of tyrosine 3-monooxygenase activity-%%-GO:0007338-&&-single fertilization-%%-GO:0019249-&&-lactate biosynthetic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1902177-&&-positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:1903197-&&-positive regulation of L-dopa biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0036526-&&-peptidyl-cysteine deglycation-%%-GO:0042743-&&-hydrogen peroxide metabolic process-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1903168-&&-positive regulation of pyrroline-5-carboxylate reductase activity-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:1903208-&&-negative regulation of hydrogen peroxide-induced neuron death-%%-GO:1903384-&&-negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0010273-&&-detoxification of copper ion-%%-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:2001268-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0044297-&&-cell body-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0016605-&&-PML body-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0044388-&&-small protein activating enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0044390-&&-ubiquitin-like protein conjugating enzyme binding-%%-GO:0045340-&&-mercury ion binding-%%-GO:0036524-&&-protein deglycase activity-%%-GO:1903136-&&-cuprous ion binding-%%-GO:0016532-&&-superoxide dismutase copper chaperone activity-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0036470-&&-tyrosine 3-monooxygenase activator activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001047-&&-core promoter binding-%%-GO:1903135-&&-cupric ion binding-%%-GO:0019900-&&-kinase binding-%%-GO:0036478-&&-L-dopa decarboxylase activator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0016684-&&-oxidoreductase activity, acting on peroxide as acceptor-%%-GO:0019955-&&-cytokine binding-%%-GO:0051920-&&-peroxiredoxin activity	G:9606:PARK7			KEGG-&-1&-hsa05012-&&-Parkinson disease	PARK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARK7	0.41380884	0.12956108	64	4	FALSE	PARK7	PARK7	168.5483871	0	63	0	0.76390421	FALSE	1	PARK7	248142	0.04586721
790252	taxon:9606	2.35701906	2.39E-04	173509	1902	ubiquitin protein ligase E3 component n-recognin 4	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:UBR4			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	UBR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR4	0.42426471	0.11160714	64	4	FALSE	UBR4	UBR4	187.421875	0	64	0	0.77383016	FALSE	0	UBR4	365000	0.04642205
791075	taxon:9606	2.39766819	1.10E-04	170128	1902	ATPase family, AAA domain containing 3A	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:ATAD3A	ATAD3A	TRUE		ATAD3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD3A	0.41707189	0.10019841	64	4	FALSE	ATAD3A	ATAD3A	236	0	64	0	0.7670553	FALSE	0	ATAD3A	327670	0.06245451
791526	taxon:9606	2.44052308	6.26E-05	168249	1902	transducin beta like 1 X-linked receptor 1	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0002021-&&-response to dietary excess-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060613-&&-fat pad development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0016575-&&-histone deacetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090207-&&-regulation of triglyceride metabolic process-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030814-&&-regulation of cAMP metabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:TBL1XR1	TBL1XR1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	TBL1XR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL1XR1	0.40974822	0.18700397	64	4	FALSE	TBL1XR1	TBL1XR1	200.375	0	64	0	0.75991282	FALSE	0	TBL1XR1	164804	0.05651886
791557	taxon:9606	2.76098944	1.29E-04	168048	1902	tectonic family member 1	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0001841-&&-neural tube formation-%%-GO:0021523-&&-somatic motor neuron differentiation-%%-GO:1904491-&&-protein localization to ciliary transition zone-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0021956-&&-central nervous system interneuron axonogenesis-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0021537-&&-telencephalon development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0036038-&&-MKS complex	G:9606:TCTN1				TCTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCTN1	0.362189	0.05208333	64	4	FALSE	TCTN1	TCTN1	51.734375	0	64	0	0.70650176	FALSE	0	TCTN1	132280	0.03388158
791804	taxon:9606	2.48715929	3.01E-04	166785	1902	synoviolin 1	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0036503-&&-ERAD pathway-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0000836-&&-Hrd1p ubiquitin ligase complex-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000839-&&-Hrd1p ubiquitin ligase ERAD-L complex-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0051117-&&-ATPase binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway	G:9606:SYVN1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SYVN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYVN1	0.40206512	0.13167636	64	4	FALSE	SYVN1	SYVN1	112.1129032	0	63	0	0.75214012	FALSE	1	SYVN1	320710	0.03492863
792021	taxon:9606	2.42114385	1.33E-04	182720	1902	Bloom syndrome RecQ like helicase	gene	biological_process-&-1&-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0048478-&&-replication fork protection-%%-GO:0006260-&&-DNA replication-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0031297-&&-replication fork processing-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0072757-&&-cellular response to camptothecin-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0044806-&&-G-quadruplex DNA unwinding-%%-GO:0000732-&&-strand displacement-%%-GO:0010165-&&-response to X-ray-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0006281-&&-DNA repair-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0090656-&&-t-circle formation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0006310-&&-DNA recombination-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0016605-&&-PML body-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005657-&&-replication fork-%%-GO:0005634-&&-nucleus-%%-GO:0000800-&&-lateral element-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0009378-&&-four-way junction helicase activity-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0061821-&&-telomeric D-loop binding-%%-GO:0000403-&&-Y-form DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0000405-&&-bubble DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0061749-&&-forked DNA-dependent helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0036310-&&-annealing helicase activity-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004386-&&-helicase activity-%%-GO:0051880-&&-G-quadruplex DNA binding	G:9606:BLM			KEGG-&-1&-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway	BLM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLM	0.41302792	0.17239556	64	4	FALSE	BLM	BLM	176.5322581	0	63	0	0.76314269	FALSE	1	BLM	215684	0.04818455
792443	taxon:9606	2.38159761	8.92E-05	182008	1902	CTP synthase 1	gene	biological_process-&-1&-GO:0044210-&&-'de novo' CTP biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0042098-&&-T cell proliferation-%%-GO:0006241-&&-CTP biosynthetic process-%%-GO:0042100-&&-B cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0006541-&&-glutamine metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003883-&&-CTP synthase activity-%%-GO:0042802-&&-identical protein binding	G:9606:CTPS1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways	CTPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTPS1	0.41988621	0.13696457	64	4	FALSE	CTPS1	CTPS1	230.8387097	0	63	0	0.76973373	FALSE	1	CTPS1	212510	0.05932913
792634	taxon:9606	2.2754057	1.29E-04	181683	1902	eukaryotic translation elongation factor 1 beta 2	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005853-&&-eukaryotic translation elongation factor 1 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EEF1B2				EEF1B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1B2	0.43948207	0.2141724	64	4	FALSE	EEF1B2	EEF1B2	296.5645161	0	63	0	0.78743238	FALSE	1	EEF1B2	278630	0.06518625
792652	taxon:9606	2.66409327	2.45E-04	181639	1902	cytochrome P450 family 1 subfamily A member 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0009635-&&-response to herbicide-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0009804-&&-coumarin metabolic process-%%-GO:0070988-&&-demethylation-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043010-&&-camera-type eye development-%%-GO:0002933-&&-lipid hydroxylation-%%-GO:0042904-&&-9-cis-retinoic acid biosynthetic process-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0008283-&&-cell proliferation-%%-GO:0010041-&&-response to iron(III) ion-%%-GO:0097267-&&-omega-hydroxylase P450 pathway-%%-GO:0019341-&&-dibenzo-p-dioxin catabolic process-%%-GO:0006778-&&-porphyrin-containing compound metabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0009812-&&-flavonoid metabolic process-%%-GO:0017143-&&-insecticide metabolic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0046677-&&-response to antibiotic-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0042493-&&-response to drug-%%-GO:0032094-&&-response to food-%%-GO:0033189-&&-response to vitamin A-%%-GO:0042359-&&-vitamin D metabolic process-%%-GO:0060137-&&-maternal process involved in parturition-%%-GO:0009611-&&-response to wounding-%%-GO:0035902-&&-response to immobilization stress-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048565-&&-digestive tract development-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009692-&&-ethylene metabolic process-%%-GO:0007568-&&-aging-%%-GO:0009624-&&-response to nematode|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0070576-&&-vitamin D 24-hydroxylase activity-%%-GO:0101020-&&-estrogen 16-alpha-hydroxylase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0016679-&&-oxidoreductase activity, acting on diphenols and related substances as donors-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0070330-&&-aromatase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding-%%-GO:0032451-&&-demethylase activity-%%-GO:0016711-&&-flavonoid 3'-monooxygenase activity-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding	G:9606:CYP1A1	CYP1A1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CYP1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP1A1	0.37536223	0.01785714	64	4	FALSE	CYP1A1	CYP1A1	59.390625	0	64	0	0.72265112	FALSE	0	CYP1A1	239962	0.02769553
792799	taxon:9606	2.49866078	1.32E-04	181354	1902	eukaryotic translation initiation factor 4A2	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006413-&&-translational initiation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0016032-&&-viral process-%%-GO:1900260-&&-negative regulation of RNA-directed 5'-3' RNA polymerase activity|cellular_component-&-1&-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0004386-&&-helicase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF4A2			KEGG-&-1&-hsa03013-&&-RNA transport	EIF4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4A2	0.40021439	0.08778424	64	4	FALSE	EIF4A2	EIF4A2	126.516129	0	63	0	0.7502232	FALSE	1	EIF4A2	186888	0.04009992
793117	taxon:9606	2.45769655	5.92E-05	180697	1902	glutamine--fructose-6-phosphate transaminase 1	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0006048-&&-UDP-N-acetylglucosamine biosynthetic process-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0097367-&&-carbohydrate derivative binding-%%-GO:0004360-&&-glutamine-fructose-6-phosphate transaminase (isomerizing) activity	G:9606:GFPT1	GFPT1	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa04931-&&-Insulin resistance	GFPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFPT1	0.40688506	0.16319444	64	4	FALSE	GFPT1	GFPT1	181.0625	0	64	0	0.75705058	FALSE	0	GFPT1	151958	0.05284953
793333	taxon:9606	2.51993068	2.85E-04	180305	1902	major histocompatibility complex, class I, C	gene	biological_process-&-1&-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0016032-&&-viral process-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0009986-&&-cell surface-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding-%%-GO:0005102-&&-receptor binding	G:9606:HLA-C			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04144-&&-Endocytosis-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	HLA-C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-C	0.39683631	0.06345849	64	4	FALSE	HLA-C	HLA-C	117.2096774	0	63	0	0.74667822	FALSE	1	HLA-C	306136	0.03879094
787308	taxon:9606	2.44320151	1.25E-04	179681	1902	karyopherin subunit alpha 3	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0019054-&&-modulation by virus of host process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0075732-&&-viral penetration into host nucleus|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:KPNA3				KPNA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA3	0.40929903	0.09318996	63	4	FALSE	KPNA3	KPNA3	142.6984127	0	63	0	0.75946641	FALSE	0	KPNA3	202196	0.04062063
787388	taxon:9606	2.37340476	1.07E-04	179513	1902	myosin VI	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006897-&&-endocytosis-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042493-&&-response to drug-%%-GO:0051046-&&-regulation of secretion|cellular_component-&-1&-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031941-&&-filamentous actin-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0001726-&&-ruffle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045177-&&-apical part of cell-%%-GO:0016461-&&-unconventional myosin complex-%%-GO:0032587-&&-ruffle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005902-&&-microvillus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0060001-&&-minus-end directed microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0003774-&&-motor activity-%%-GO:0043531-&&-ADP binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding	G:9606:MYO6				MYO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO6	0.42133563	0.16666667	63	4	FALSE	MYO6	MYO6	197.0655738	0	62	0	0.77109921	FALSE	1	MYO6	210338	0.0499491
787419	taxon:9606	2.49519458	5.68E-05	179464	1902	lamin B receptor	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0016126-&&-sterol biosynthetic process-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005639-&&-integral component of nuclear inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016627-&&-oxidoreductase activity, acting on the CH-CH group of donors-%%-GO:0070087-&&-chromo shadow domain binding-%%-GO:0050613-&&-delta14-sterol reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005521-&&-lamin binding	G:9606:LBR	LBR	TRUE		LBR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LBR	0.40077035	0.27650273	63	4	FALSE	LBR	LBR	255.704918	0	62	0	0.7508009	FALSE	1	LBR	208454	0.07973267
787496	taxon:9606	2.57444462	2.45E-04	179337	1902	membrane metalloendopeptidase	gene	biological_process-&-1&-GO:0002003-&&-angiotensin maturation-%%-GO:0090399-&&-replicative senescence-%%-GO:0001822-&&-kidney development-%%-GO:0006518-&&-peptide metabolic process-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0006508-&&-proteolysis-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071492-&&-cellular response to UV-A-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0050435-&&-beta-amyloid metabolic process|cellular_component-&-1&-GO:0044306-&&-neuron projection terminus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0045202-&&-synapse-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005903-&&-brush border-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0008238-&&-exopeptidase activity	G:9606:MME			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04614-&&-Renin-angiotensin system-%%-hsa04974-&&-Protein digestion and absorption	MME	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MME	0.38843329	0.03551913	63	4	FALSE	MME	MME	103.4754098	0	62	0	0.73759256	FALSE	1	MME	321100	0.03877336
787907	taxon:9606	2.44997637	7.60E-05	178634	1902	proteasome activator subunit 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0008537-&&-proteasome activator complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0061133-&&-endopeptidase activator activity-%%-GO:0005515-&&-protein binding	G:9606:PSME1			KEGG-&-1&-hsa03050-&&-Proteasome-%%-hsa04612-&&-Antigen processing and presentation	PSME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSME1	0.4081672	0.2284153	63	4	FALSE	PSME1	PSME1	155.7377049	0	62	0	0.75833727	FALSE	1	PSME1	160536	0.04508315
788857	taxon:9606	2.42334961	2.20E-04	176747	1902	vav guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030168-&&-platelet activation-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0001525-&&-angiogenesis-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008361-&&-regulation of cell size|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:VAV2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04660-&&-T cell receptor signaling pathway	VAV2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAV2	0.41265197	0.07650273	63	4	FALSE	VAV2	VAV2	140.295082	0	62	0	0.76277506	FALSE	1	VAV2	279174	0.038796
788889	taxon:9606	2.53206239	7.15E-05	176665	1902	XPC complex subunit, DNA damage recognition and repair factor	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006281-&&-DNA repair-%%-GO:0042493-&&-response to drug-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:0006298-&&-mismatch repair-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0010224-&&-response to UV-B-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000111-&&-nucleotide-excision repair factor 2 complex-%%-GO:0071942-&&-XPC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0000404-&&-heteroduplex DNA loop binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000405-&&-bubble DNA binding	G:9606:XPC			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	XPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPC	0.39493498	0.18196721	63	4	FALSE	XPC	XPC	195.6557377	0	62	0	0.74465627	FALSE	1	XPC	181252	0.06608883
788925	taxon:9606	2.51536159	8.37E-05	176586	1902	serine/threonine kinase 24	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0048679-&&-regulation of axon regeneration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:STK24				STK24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK24	0.39755716	0.13879781	63	4	FALSE	STK24	STK24	133.0163934	0	62	0	0.74743974	FALSE	1	STK24	145250	0.04333813
789265	taxon:9606	2.37277454	4.96E-05	175872	1902	serine and arginine rich splicing factor 9	gene	biological_process-&-1&-GO:0009636-&&-response to toxic substance-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0043279-&&-response to alkaloid-%%-GO:0006397-&&-mRNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SRSF9			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF9	0.42144754	0.28264209	63	4	FALSE	SRSF9	SRSF9	247	0	63	0	0.77120424	FALSE	0	SRSF9	135252	0.06272219
789438	taxon:9606	2.44698283	3.49E-04	175475	1902	SLC9A3 regulator 1	gene	biological_process-&-1&-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0070293-&&-renal absorption-%%-GO:0030033-&&-microvillus assembly-%%-GO:0030643-&&-cellular phosphate ion homeostasis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0044062-&&-regulation of excretion-%%-GO:0032415-&&-regulation of sodium:proton antiporter activity-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006461-&&-protein complex assembly-%%-GO:0097291-&&-renal phosphate ion absorption-%%-GO:0032416-&&-negative regulation of sodium:proton antiporter activity-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0003096-&&-renal sodium ion transport-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0034635-&&-glutathione transport-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0040023-&&-establishment of nucleus localization-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0032782-&&-bile acid secretion|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0031526-&&-brush border membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0012505-&&-endomembrane system-%%-GO:0031528-&&-microvillus membrane-%%-GO:0032426-&&-stereocilium tip-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0097225-&&-sperm midpiece-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0001726-&&-ruffle-%%-GO:0016020-&&-membrane-%%-GO:0005902-&&-microvillus|molecular_function-&-1&-GO:0017081-&&-chloride channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0050780-&&-dopamine receptor binding-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0043621-&&-protein self-association-%%-GO:0019902-&&-phosphatase binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0070851-&&-growth factor receptor binding	G:9606:SLC9A3R1			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	SLC9A3R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC9A3R1	0.40866654	0.10601093	63	4	FALSE	SLC9A3R1	SLC9A3R1	139.5737705	0	62	0	0.7588362	FALSE	1	SLC9A3R1	388382	0.04022728
789465	taxon:9606	2.50133922	1.97E-04	175410	1902	BCAR1, Cas family scaffolding protein	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0016477-&&-cell migration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0050851-&&-antigen receptor-mediated signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0008283-&&-cell proliferation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007015-&&-actin filament organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:BCAR1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05163-&&-Human cytomegalovirus infection	BCAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAR1	0.39978584	0.16026626	63	4	FALSE	BCAR1	BCAR1	132.7460318	0	63	0	0.7497768	FALSE	0	BCAR1	255742	0.04241428
789505	taxon:9606	2.40853947	1.22E-04	175312	1902	clathrin interactor 1	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:CLINT1				CLINT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLINT1	0.41518938	0.18032787	63	4	FALSE	CLINT1	CLINT1	195.9672131	0	62	0	0.76524342	FALSE	1	CLINT1	249876	0.05264224
789817	taxon:9606	2.45848432	1.89E-04	174589	1902	ubiquitin specific peptidase 19	gene	biological_process-&-1&-GO:1904292-&&-regulation of ERAD pathway-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:1900037-&&-regulation of cellular response to hypoxia-%%-GO:0050821-&&-protein stabilization-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0090068-&&-positive regulation of cell cycle process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0046872-&&-metal ion binding	G:9606:USP19				USP19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP19	0.40675468	0.06605223	63	4	FALSE	USP19	USP19	125.6031746	0	63	0	0.75691928	FALSE	0	USP19	250396	0.03675514
790148	taxon:9606	2.39404443	1.99E-04	173767	1902	tripartite motif containing 32	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0061564-&&-axon development-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:1903886-&&-positive regulation of chemokine (C-C motif) ligand 20 production-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0009411-&&-response to UV-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0051155-&&-positive regulation of striated muscle cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0045087-&&-innate immune response-%%-GO:0007014-&&-actin ubiquitination-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1903883-&&-positive regulation of interleukin-17-mediated signaling pathway-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:1903265-&&-positive regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005863-&&-striated muscle myosin thick filament|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017022-&&-myosin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0043621-&&-protein self-association-%%-GO:0030957-&&-Tat protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:TRIM32			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	TRIM32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM32	0.41770319	0.11092896	63	4	FALSE	TRIM32	TRIM32	174.8196721	0	62	0	0.76765926	FALSE	1	TRIM32	309608	0.04586635
790327	taxon:9606	2.4495037	1.67E-04	173307	1902	gem nuclear organelle associated protein 5	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006412-&&-translation-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0016020-&&-membrane-%%-GO:0032797-&&-SMN complex-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol-%%-GO:0034718-&&-SMN-Gemin2 complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030621-&&-U4 snRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0030622-&&-U4atac snRNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:0017069-&&-snRNA binding-%%-GO:0030619-&&-U1 snRNA binding	G:9606:GEMIN5			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN5	0.40824596	0.15258577	63	4	FALSE	GEMIN5	GEMIN5	179.3968254	0	63	0	0.75841605	FALSE	0	GEMIN5	260476	0.05156676
790546	taxon:9606	2.46809516	1.89E-04	172531	1902	HtrA serine peptidase 2	gene	biological_process-&-1&-GO:0016540-&&-protein autoprocessing-%%-GO:1904924-&&-negative regulation of mitophagy in response to mitochondrial depolarization-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006508-&&-proteolysis-%%-GO:0009635-&&-response to herbicide-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0007628-&&-adult walking behavior-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0030900-&&-forebrain development-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0019742-&&-pentacyclic triterpenoid metabolic process-%%-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0048666-&&-neuron development-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0034605-&&-cellular response to heat-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0051082-&&-unfolded protein binding	G:9606:HTRA2			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa05012-&&-Parkinson disease-%%-hsa04210-&&-Apoptosis	HTRA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTRA2	0.40517076	0.06885246	63	4	FALSE	HTRA2	HTRA2	120.7704918	0	62	0	0.75531747	FALSE	1	HTRA2	248446	0.03615002
791134	taxon:9606	2.48195998	1.78E-04	169935	1902	NSFL1 cofactor	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0007030-&&-Golgi organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005795-&&-Golgi stack-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990730-&&-VCP-NSFL1C complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:NSFL1C			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	NSFL1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSFL1C	0.40290738	0.10701485	63	4	FALSE	NSFL1C	NSFL1C	137.1587302	0	63	0	0.75300667	FALSE	0	NSFL1C	235210	0.04205692
791242	taxon:9606	2.45312746	1.39E-04	169551	1902	par-3 family cell polarity regulator	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0060341-&&-regulation of cellular localization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0008356-&&-asymmetric cell division-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0007409-&&-axonogenesis-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0007163-&&-establishment or maintenance of cell polarity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0033269-&&-internode region of axon-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0012505-&&-endomembrane system-%%-GO:0043234-&&-protein complex-%%-GO:0044295-&&-axonal growth cone-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:PARD3			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05165-&&-Human papillomavirus infection	PARD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARD3	0.4076429	0.11639344	63	4	FALSE	PARD3	PARD3	146.3278689	0	62	0	0.75781209	FALSE	1	PARD3	215170	0.04251528
791674	taxon:9606	2.66472349	1.66E-04	167480	1902	centrosomal protein 70	gene	biological_process-&-1&-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP70				CEP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP70	0.37527346	0.03825137	63	4	FALSE	CEP70	CEP70	72.16393443	0	62	0	0.72254608	FALSE	1	CEP70	181576	0.03393187
791771	taxon:9606	2.56105247	3.43E-05	166950	1902	lysine acetyltransferase 8	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0016573-&&-histone acetylation|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072487-&&-MSL complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)	G:9606:KAT8				KAT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT8	0.39046447	0.30163934	63	4	FALSE	KAT8	KAT8	218.0327869	0	62	0	0.73982459	FALSE	1	KAT8	112542	0.07758007
791867	taxon:9606	2.32093903	8.57E-05	182956	1902	ATP citrate lyase	gene	biological_process-&-1&-GO:0006101-&&-citrate metabolic process-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0006085-&&-acetyl-CoA biosynthetic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0009346-&&-citrate lyase complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0048037-&&-cofactor binding-%%-GO:0003878-&&-ATP citrate synthase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ACLY			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways	ACLY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACLY	0.43086009	0.14371585	63	4	FALSE	ACLY	ACLY	258.0163934	0	62	0	0.7798435	FALSE	1	ACLY	219498	0.06051041
792253	taxon:9606	2.58342524	1.86E-04	165963	1902	membrane magnesium transporter 1	gene	biological_process-&-1&-GO:1903830-&&-magnesium ion transmembrane transport-%%-GO:0015693-&&-magnesium ion transport-%%-GO:0098655-&&-cation transmembrane transport|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0031901-&&-early endosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0072546-&&-ER membrane protein complex|molecular_function-&-1&-GO:0015095-&&-magnesium ion transmembrane transporter activity-%%-GO:0022890-&&-inorganic cation transmembrane transporter activity	G:9606:MMGT1				MMGT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMGT1	0.387083	0.06144393	63	4	FALSE	MMGT1	MMGT1	83.84126984	0	63	0	0.73609579	FALSE	0	MMGT1	203786	0.03203806
792515	taxon:9606	2.48022688	6.94E-05	165486	1902	ubiquitin like with PHD and ring finger domains 2	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0090308-&&-regulation of methylation-dependent chromatin silencing-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0008283-&&-cell proliferation-%%-GO:0007049-&&-cell cycle-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UHRF2				UHRF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UHRF2	0.40318892	0.19945355	63	4	FALSE	UHRF2	UHRF2	200.0819672	0	62	0	0.75329552	FALSE	1	UHRF2	177986	0.06095843
792962	taxon:9606	2.58169214	1.59E-04	181082	1902	fumarate hydratase	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006108-&&-malate metabolic process-%%-GO:0006106-&&-fumarate metabolic process-%%-GO:0048873-&&-homeostasis of number of cells within a tissue|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0045239-&&-tricarboxylic acid cycle enzyme complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004333-&&-fumarate hydratase activity-%%-GO:0005515-&&-protein binding	G:9606:FH			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04934-&&-Cushing syndrome	FH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FH	0.38734285	0.10240655	63	4	FALSE	FH	FH	96.26984127	0	63	0	0.73638464	FALSE	0	FH	205888	0.03622227
793160	taxon:9606	2.67071057	3.08E-04	180618	1902	G protein subunit alpha i1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051301-&&-cell division-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:1904322-&&-cellular response to forskolin-%%-GO:0043949-&&-regulation of cAMP-mediated signaling-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0030496-&&-midbody-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0019003-&&-GDP binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNAI1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05030-&&-Cocaine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04540-&&-Gap junction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05133-&&-Pertussis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAI1	0.37443219	0.07103825	63	4	FALSE	GNAI1	GNAI1	60.7704918	0	62	0	0.72154824	FALSE	1	GNAI1	310754	0.0291439
793246	taxon:9606	2.53206239	1.56E-04	180452	1902	inhibitor of DNA binding 2, HLH protein	gene	biological_process-&-1&-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0048541-&&-Peyer's patch development-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0045578-&&-negative regulation of B cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0061030-&&-epithelial cell differentiation involved in mammary gland alveolus development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0060612-&&-adipose tissue development-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0061031-&&-endodermal digestive tract morphogenesis-%%-GO:0001656-&&-metanephros development-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0090398-&&-cellular senescence-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0007275-&&-multicellular organism development-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0071931-&&-positive regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048469-&&-cell maturation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0003166-&&-bundle of His development-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0001966-&&-thigmotaxis-%%-GO:0045475-&&-locomotor rhythm-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0043392-&&-negative regulation of DNA binding|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0044325-&&-ion channel binding	G:9606:ID2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	ID2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ID2	0.39493498	0.06393443	63	4	FALSE	ID2	ID2	117.8688525	0	62	0	0.74465627	FALSE	1	ID2	231288	0.03969346
787179	taxon:9606	2.46856783	1.73E-04	179912	1902	MAD2 mitotic arrest deficient-like 1 (yeast)	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:1904667-&&-negative regulation of ubiquitin protein ligase activity-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MAD2L1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	MAD2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAD2L1	0.40509318	0.07288136	62	4	FALSE	MAD2L1	MAD2L1	115.4	0	61	0	0.7552387	FALSE	1	MAD2L1	230042	0.03448001
787203	taxon:9606	2.38380337	1.47E-04	179868	1902	microtubule associated protein 4	gene	biological_process-&-1&-GO:0031175-&&-neuron projection development-%%-GO:0051301-&&-cell division-%%-GO:0051012-&&-microtubule sliding-%%-GO:0051294-&&-establishment of spindle orientation-%%-GO:1902856-&&-negative regulation of non-motile cilium assembly-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005930-&&-axoneme-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043005-&&-neuron projection-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005198-&&-structural molecule activity	G:9606:MAP4				MAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP4	0.41949769	0.09783184	62	4	FALSE	MAP4	MAP4	189.4193548	0	62	0	0.7693661	FALSE	0	MAP4	267538	0.04898818
787309	taxon:9606	2.41106034	9.71E-05	179680	1902	karyopherin subunit alpha 4	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0019054-&&-modulation by virus of host process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNA4				KPNA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA4	0.41475528	0.11898466	62	4	FALSE	KPNA4	KPNA4	160.6451613	0	62	0	0.76482328	FALSE	0	KPNA4	188302	0.0432496
787318	taxon:9606	2.51378604	2.75E-04	179675	1902	KRAS proto-oncogene, GTPase	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050900-&&-leukocyte migration-%%-GO:0021897-&&-forebrain astrocyte development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0001889-&&-liver development-%%-GO:0007565-&&-female pregnancy-%%-GO:0008542-&&-visual learning-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0038002-&&-endocrine signaling-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0035900-&&-response to isolation stress-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0051385-&&-response to mineralocorticoid-%%-GO:0035022-&&-positive regulation of Rac protein signal transduction-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030275-&&-LRR domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019002-&&-GMP binding-%%-GO:0003924-&&-GTPase activity	G:9606:KRAS	KRAS	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	KRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRAS	0.39780633	0.02273929	62	4	FALSE	KRAS	KRAS	91.87096774	0	62	0	0.74770233	FALSE	0	KRAS	333022	0.0303074
787542	taxon:9606	2.35197731	1.29E-04	179216	1902	protein phosphatase 2 regulatory subunit Balpha	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0032502-&&-developmental process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043278-&&-response to morphine-%%-GO:0070262-&&-peptidyl-serine dephosphorylation|cellular_component-&-1&-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0048156-&&-tau protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:PPP2R2A			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R2A	0.42517417	0.16763617	62	4	FALSE	PPP2R2A	PPP2R2A	193.5967742	0	62	0	0.77467045	FALSE	0	PPP2R2A	242558	0.04734575
787571	taxon:9606	2.62785568	1.23E-04	179158	1902	NADH:ubiquinone oxidoreductase core subunit V1	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005829-&&-cytosol-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0010181-&&-FMN binding	G:9606:NDUFV1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFV1	0.3805384	0.14648334	62	4	FALSE	NDUFV1	NDUFV1	85.64516129	0	62	0	0.72869072	FALSE	0	NDUFV1	164998	0.0361795
787641	taxon:9606	2.43595399	1.47E-04	162651	1902	RPTOR independent companion of MTOR complex 2	gene	biological_process-&-1&-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0009790-&&-embryo development-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0030950-&&-establishment or maintenance of actin cytoskeleton polarity-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0031929-&&-TOR signaling-%%-GO:0042325-&&-regulation of phosphorylation|cellular_component-&-1&-GO:0031932-&&-TORC2 complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0019901-&&-protein kinase binding	G:9606:RICTOR			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	RICTOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RICTOR	0.41051678	0.1300899	62	4	FALSE	RICTOR	RICTOR	163.2258065	0	62	0	0.76067433	FALSE	0	RICTOR	226946	0.04590152
787719	taxon:9606	2.50212699	1.03E-04	178881	1902	PMS1 homolog 2, mismatch repair system component	gene	biological_process-&-1&-GO:0042493-&&-response to drug-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0006298-&&-mismatch repair-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032389-&&-MutLalpha complex-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0004519-&&-endonuclease activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032138-&&-single base insertion or deletion binding-%%-GO:0032407-&&-MutSalpha complex binding	G:9606:PMS2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03460-&&-Fanconi anemia pathway	PMS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMS2	0.39965997	0.08725542	62	4	FALSE	PMS2	PMS2	134.8225807	0	62	0	0.7496455	FALSE	0	PMS2	195924	0.04286535
787813	taxon:9606	2.37482275	1.81E-04	178752	1902	protein kinase C iota	gene	biological_process-&-1&-GO:0035089-&&-establishment of apical/basal cell polarity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0048194-&&-Golgi vesicle budding-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007015-&&-actin filament organization-%%-GO:0061024-&&-membrane organization-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0016477-&&-cell migration-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0046903-&&-secretion-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031252-&&-cell leading edge-%%-GO:0043234-&&-protein complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005543-&&-phospholipid binding	G:9606:PRKCI			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	PRKCI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCI	0.42108406	0.10735061	62	4	FALSE	PRKCI	PRKCI	158.6451613	0	62	0	0.77086287	FALSE	0	PRKCI	279908	0.04037185
787818	taxon:9606	2.44131086	3.97E-04	178751	1902	protein kinase N1	gene	biological_process-&-1&-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0003014-&&-renal system process-%%-GO:0010631-&&-epithelial cell migration-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0002637-&&-regulation of immunoglobulin production-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048536-&&-spleen development-%%-GO:0035407-&&-histone H3-T11 phosphorylation-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032154-&&-cleavage furrow-%%-GO:0043234-&&-protein complex-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0017049-&&-GTP-Rho binding-%%-GO:0035402-&&-histone kinase activity (H3-T11 specific)	G:9606:PKN1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05132-&&-Salmonella infection	PKN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKN1	0.40961601	0.06892655	62	4	FALSE	PKN1	PKN1	129.9833333	0	61	0	0.75978152	FALSE	1	PKN1	463006	0.03697902
787819	taxon:9606	2.49866078	1.79E-04	178750	1902	protein kinase N2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043297-&&-apical junction assembly-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010631-&&-epithelial cell migration|cellular_component-&-1&-GO:0043296-&&-apical junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032154-&&-cleavage furrow-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0030496-&&-midbody-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005524-&&-ATP binding	G:9606:PKN2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05132-&&-Salmonella infection	PKN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKN2	0.40021439	0.05706215	62	4	FALSE	PKN2	PKN2	115.8333333	0	61	0	0.7502232	FALSE	1	PKN2	231932	0.03661912
787905	taxon:9606	2.49046794	8.24E-05	178638	1902	proteasome 26S subunit, non-ATPase 10	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070682-&&-proteasome regulatory particle assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000502-&&-proteasome complex-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005838-&&-proteasome regulatory particle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PSMD10				PSMD10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD10	0.40153097	0.21152829	62	4	FALSE	PSMD10	PSMD10	157.8709677	0	62	0	0.75158868	FALSE	0	PSMD10	172342	0.0491561
788274	taxon:9606	2.36568458	1.93E-04	177966	1902	ribosomal protein S6 kinase A3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0007165-&&-signal transduction-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0043555-&&-regulation of translation in response to stress-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0007417-&&-central nervous system development-%%-GO:0001501-&&-skeletal system development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:RPS6KA3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	RPS6KA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA3	0.42271062	0.12542373	62	4	FALSE	RPS6KA3	RPS6KA3	215.85	0	61	0	0.7723859	FALSE	1	RPS6KA3	347674	0.05402169
788478	taxon:9606	2.47093115	1.16E-04	177568	1902	small ubiquitin-like modifier 3	gene	biological_process-&-1&-GO:0016925-&&-protein sumoylation-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0000776-&&-kinetochore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0005515-&&-protein binding	G:9606:SUMO3			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa03013-&&-RNA transport	SUMO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUMO3	0.40470573	0.08725542	62	4	FALSE	SUMO3	SUMO3	143.4516129	0	62	0	0.75484481	FALSE	0	SUMO3	207380	0.04302043
788481	taxon:9606	2.42634315	2.25E-04	177565	1902	snail family transcriptional repressor 1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0060972-&&-left/right pattern formation-%%-GO:0001707-&&-mesoderm formation-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060806-&&-negative regulation of cell differentiation involved in embryonic placenta development-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0060021-&&-palate development-%%-GO:0060707-&&-trophoblast giant cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019900-&&-kinase binding	G:9606:SNAI1			KEGG-&-1&-hsa04520-&&-Adherens junction	SNAI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAI1	0.41214286	0.20306716	62	4	FALSE	SNAI1	SNAI1	215.6451613	0	62	0	0.76227614	FALSE	0	SNAI1	437890	0.05992001
788547	taxon:9606	2.49283126	2.67E-04	177463	1902	sterol regulatory element binding transcription factor 1	gene	biological_process-&-1&-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0045542-&&-positive regulation of cholesterol biosynthetic process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0019217-&&-regulation of fatty acid metabolic process-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0003062-&&-regulation of heart rate by chemical signal-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0030324-&&-lung development-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0009749-&&-response to glucose-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0042493-&&-response to drug-%%-GO:0032094-&&-response to food-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006629-&&-lipid metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0033762-&&-response to glucagon-%%-GO:0007568-&&-aging-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0032810-&&-sterol response element binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0032403-&&-protein complex binding	G:9606:SREBF1	SREBF1	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04931-&&-Insulin resistance	SREBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREBF1	0.4011503	0.16497175	62	4	FALSE	SREBF1	SREBF1	133.7833333	0	61	0	0.75119479	FALSE	1	SREBF1	308536	0.04176556
788552	taxon:9606	2.4376871	1.59E-04	177454	1902	SPT6 homolog, histone chaperone	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051028-&&-mRNA transport-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006342-&&-chromatin silencing-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0070827-&&-chromatin maintenance-%%-GO:0051147-&&-regulation of muscle cell differentiation-%%-GO:0008380-&&-RNA splicing-%%-GO:0045191-&&-regulation of isotype switching-%%-GO:0034728-&&-nucleosome organization-%%-GO:0006397-&&-mRNA processing-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0006338-&&-chromatin remodeling|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000991-&&-transcription factor activity, core RNA polymerase II binding-%%-GO:0031491-&&-nucleosome binding	G:9606:SUPT6H				SUPT6H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT6H	0.41022492	0.12321523	62	4	FALSE	SUPT6H	SUPT6H	223.5322581	0	62	0	0.76038548	FALSE	0	SUPT6H	276204	0.06297051
788591	taxon:9606	2.55931936	5.58E-05	177386	1902	transducin beta like 1X-linked	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0017053-&&-transcriptional repressor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:TBL1X			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	TBL1X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL1X	0.39072888	0.14463277	62	4	FALSE	TBL1X	TBL1X	158.7666667	0	61	0	0.74011344	FALSE	1	TBL1X	134792	0.0567537
788705	taxon:9606	2.3864818	7.70E-05	177148	1902	topoisomerase (DNA) II beta	gene	biological_process-&-1&-GO:0006312-&&-mitotic recombination-%%-GO:0001764-&&-neuron migration-%%-GO:0016925-&&-protein sumoylation-%%-GO:0000819-&&-sister chromatid segregation-%%-GO:0006265-&&-DNA topological change-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0007409-&&-axonogenesis-%%-GO:0044774-&&-mitotic DNA integrity checkpoint-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000792-&&-heterochromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003918-&&-DNA topoisomerase type II (ATP-hydrolyzing) activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:TOP2B			KEGG-&-1&-hsa01524-&&-Platinum drug resistance	TOP2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOP2B	0.41902687	0.20847458	62	4	FALSE	TOP2B	TOP2B	224.6	0	61	0	0.7689197	FALSE	1	TOP2B	175482	0.05792709
788817	taxon:9606	2.45706633	1.71E-04	176813	1902	ubiquitin conjugating enzyme E2 E2	gene	biological_process-&-1&-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0032020-&&-ISG15-protein conjugation|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042296-&&-ISG15 transferase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2E2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2E2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2E2	0.40698942	0.05423729	62	4	FALSE	UBE2E2	UBE2E2	131.1333333	0	61	0	0.75715561	FALSE	1	UBE2E2	257506	0.03825592
789013	taxon:9606	2.50212699	1.03E-04	127230	1902	mismatch repair endonuclease PMS2	gene		G:9606:LOC107984056				LOC107984056	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC107984056	0.39965997	0.08725542	62	4	FALSE	LOC107984056	LOC107984056	134.8225807	0	62	0	0.7496455	FALSE	0	LOC107984056	195924	0.04286535
789018	taxon:9606	2.4376871	1.77E-04	176369	1902	nuclear receptor interacting protein 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007623-&&-circadian rhythm-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019915-&&-lipid storage-%%-GO:0001543-&&-ovarian follicle rupture-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0035259-&&-glucocorticoid receptor binding	G:9606:NRIP1	NRIP1	TRUE		NRIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRIP1	0.41022492	0.1173982	62	4	FALSE	NRIP1	NRIP1	148.1774194	0	62	0	0.76038548	FALSE	0	NRIP1	274064	0.04174279
789510	taxon:9606	2.520876	2.33E-04	175305	1902	Rap guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0021884-&&-forebrain neuron development-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0071321-&&-cellular response to cGMP-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:2000670-&&-positive regulation of dendritic cell apoptotic process-%%-GO:0031547-&&-brain-derived neurotrophic factor receptor signaling pathway-%%-GO:0031175-&&-neuron projection development-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:0048022-&&-negative regulation of melanin biosynthetic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001568-&&-blood vessel development-%%-GO:0001764-&&-neuron migration-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0021591-&&-ventricular system development-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0030033-&&-microvillus assembly-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0090557-&&-establishment of endothelial intestinal barrier|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0005770-&&-late endosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030553-&&-cGMP binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0017034-&&-Rap guanyl-nucleotide exchange factor activity-%%-GO:0031697-&&-beta-1 adrenergic receptor binding-%%-GO:0019992-&&-diacylglycerol binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0070300-&&-phosphatidic acid binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0050699-&&-WW domain binding	G:9606:RAPGEF2			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04530-&&-Tight junction	RAPGEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAPGEF2	0.3966875	0.04283448	62	4	FALSE	RAPGEF2	RAPGEF2	150.3709677	0	62	0	0.74652067	FALSE	0	RAPGEF2	357446	0.04984851
789812	taxon:9606	2.44367418	1.13E-04	174603	1902	BCAS2, pre-mRNA processing factor	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005813-&&-centrosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000974-&&-Prp19 complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BCAS2			KEGG-&-1&-hsa03040-&&-Spliceosome	BCAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAS2	0.40921986	0.20095188	62	4	FALSE	BCAS2	BCAS2	193.3548387	0	62	0	0.75938764	FALSE	0	BCAS2	221118	0.05521925
790223	taxon:9606	2.49346148	2.83E-04	173592	1902	PAS domain containing serine/threonine kinase	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0070092-&&-regulation of glucagon secretion-%%-GO:0043576-&&-regulation of respiratory gaseous exchange-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PASK				PASK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PASK	0.40104891	0.03502825	62	4	FALSE	PASK	PASK	104.8833333	0	61	0	0.75108975	FALSE	1	PASK	288582	0.03286178
790873	taxon:9606	2.54261856	1.06E-04	170810	1902	exosome component 4	gene	biological_process-&-1&-GO:0045006-&&-DNA deamination-%%-GO:0034475-&&-U4 snRNA 3'-end processing-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071051-&&-polyadenylation-dependent snoRNA 3'-end processing-%%-GO:0031125-&&-rRNA 3'-end processing-%%-GO:0071028-&&-nuclear mRNA surveillance-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing-%%-GO:0034427-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'-%%-GO:0016075-&&-rRNA catabolic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0071044-&&-histone mRNA catabolic process|cellular_component-&-1&-GO:0000177-&&-cytoplasmic exosome (RNase complex)-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000176-&&-nuclear exosome (RNase complex)-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0017091-&&-AU-rich element binding	G:9606:EXOSC4			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC4	0.39329533	0.10508475	62	4	FALSE	EXOSC4	EXOSC4	127.2666667	0	61	0	0.74289691	FALSE	1	EXOSC4	161138	0.04393207
791027	taxon:9606	2.52418465	1.42E-04	170313	1902	BCL6 corepressor	gene	biological_process-&-1&-GO:0000415-&&-negative regulation of histone H3-K36 methylation-%%-GO:0065001-&&-specification of axis polarity-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042476-&&-odontogenesis-%%-GO:0070171-&&-negative regulation of tooth mineralization-%%-GO:0007507-&&-heart development-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0051572-&&-negative regulation of histone H3-K4 methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060021-&&-palate development|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:BCOR				BCOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCOR	0.39616753	0.0819209	62	4	FALSE	BCOR	BCOR	120.6833333	0	61	0	0.74596922	FALSE	1	BCOR	213936	0.04006645
791452	taxon:9606	2.61729951	8.46E-05	168587	1902	DET1 and DDB1 associated 1	gene	biological_process-&-1&-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DDA1				DDA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDA1	0.3820732	0.11528292	62	4	FALSE	DDA1	DDA1	99.93548387	0	62	0	0.73045008	FALSE	0	DDA1	118262	0.04094445
791628	taxon:9606	2.55616827	1.73E-04	167744	1902	ubiquitin like modifier activating enzyme 5	gene	biological_process-&-1&-GO:0071569-&&-protein ufmylation-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0071566-&&-UFM1 activating enzyme activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:UBA5				UBA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA5	0.39121055	0.04463277	62	4	FALSE	UBA5	UBA5	105.2166667	0	61	0	0.74063862	FALSE	1	UBA5	218458	0.0373991
791888	taxon:9606	2.41925319	3.92E-04	182920	1902	G protein-coupled receptor kinase 2	gene	biological_process-&-1&-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0007217-&&-tachykinin receptor signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0033605-&&-positive regulation of catecholamine secretion-%%-GO:0045988-&&-negative regulation of striated muscle contraction-%%-GO:0003108-&&-negative regulation of the force of heart contraction by chemical signal-%%-GO:0002029-&&-desensitization of G-protein coupled receptor protein signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0019079-&&-viral genome replication|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005929-&&-cilium-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0031755-&&-Edg-2 lysophosphatidic acid receptor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031694-&&-alpha-2A adrenergic receptor binding	G:9606:GRK2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04740-&&-Olfactory transduction	GRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK2	0.4133507	0.07879429	62	4	FALSE	GRK2	GRK2	126.0967742	0	62	0	0.7634578	FALSE	0	GRK2	408982	0.03456284
792211	taxon:9606	2.42839137	2.56E-04	182401	1902	activating transcription factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0061394-&&-regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:1903984-&&-positive regulation of TRAIL-activated apoptotic signaling pathway-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:1990622-&&-CHOP-ATF3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ATF3				ATF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF3	0.41179524	0.19830508	62	4	FALSE	ATF3	ATF3	160.55	0	61	0	0.76193477	FALSE	1	ATF3	324900	0.0445787
792212	taxon:9606	2.54309122	2.31E-04	182400	1902	activating transcription factor 4	gene	biological_process-&-1&-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0061395-&&-positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:1990737-&&-response to manganese-induced endoplasmic reticulum stress-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0036091-&&-positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0034644-&&-cellular response to UV-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:1990617-&&-CHOP-ATF4 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:1990589-&&-ATF4-CREB1 transcription factor complex-%%-GO:0043005-&&-neuron projection-%%-GO:1990590-&&-ATF1-ATF4 transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:1990037-&&-Lewy body core-%%-GO:0032590-&&-dendrite membrane-%%-GO:0034399-&&-nuclear periphery|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:ATF4	ATF4	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04210-&&-Apoptosis-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF4	0.39322223	0.13107345	62	4	FALSE	ATF4	ATF4	101.0833333	0	61	0	0.74281813	FALSE	1	ATF4	254896	0.03507005
792277	taxon:9606	2.49566724	1.43E-04	182304	1902	cadherin 2	gene	biological_process-&-1&-GO:0044331-&&-cell-cell adhesion mediated by cadherin-%%-GO:1902897-&&-regulation of postsynaptic density protein 95 clustering-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0070445-&&-regulation of oligodendrocyte progenitor proliferation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0034332-&&-adherens junction organization-%%-GO:0097118-&&-neuroligin clustering involved in postsynaptic membrane assembly-%%-GO:0010001-&&-glial cell differentiation-%%-GO:0016339-&&-calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0016477-&&-cell migration-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0060563-&&-neuroepithelial cell differentiation-%%-GO:2000809-&&-positive regulation of synaptic vesicle clustering-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0060019-&&-radial glial cell differentiation|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0016342-&&-catenin complex-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0042383-&&-sarcolemma-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CDH2			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	CDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH2	0.40069444	0.0840825	62	4	FALSE	CDH2	CDH2	115.4354839	0	62	0	0.75072213	FALSE	0	CDH2	195946	0.03635384
792448	taxon:9606	2.49424925	5.03E-04	182004	1902	cathepsin D	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005764-&&-lysosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0042470-&&-melanosome-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004190-&&-aspartic-type endopeptidase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:CTSD	CTSD	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome-%%-hsa04915-&&-Estrogen signaling pathway	CTSD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSD	0.40092224	0.06327684	62	4	FALSE	CTSD	CTSD	115.7666667	0	61	0	0.75095846	FALSE	1	CTSD	499050	0.03660441
792629	taxon:9606	2.45911454	1.12E-04	181690	1902	polyhomeotic homolog 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0000792-&&-heterochromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PHC2				PHC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHC2	0.40665044	0.11073446	62	4	FALSE	PHC2	PHC2	154.9333333	0	61	0	0.75681424	FALSE	1	PHC2	209948	0.04526593
792646	taxon:9606	2.43264534	4.34E-04	181644	1902	CD44 molecule (Indian blood group)	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0051216-&&-cartilage development-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0070487-&&-monocyte aggregation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1900625-&&-positive regulation of monocyte aggregation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0035692-&&-macrophage migration inhibitory factor receptor complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005540-&&-hyaluronic acid binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0004896-&&-cytokine receptor activity	G:9606:CD44			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05131-&&-Shigellosis	CD44	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD44	0.41107513	0.10734463	62	4	FALSE	CD44	CD44	150.5833333	0	61	0	0.76122578	FALSE	1	CD44	520772	0.04237264
792766	taxon:9606	2.6037498	5.50E-05	181409	1902	DNA methyltransferase 3 alpha	gene	biological_process-&-1&-GO:0010942-&&-positive regulation of cell death-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0010288-&&-response to lead ion-%%-GO:0030182-&&-neuron differentiation-%%-GO:0042220-&&-response to cocaine-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090116-&&-C-5 methylation of cytosine-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0042493-&&-response to drug-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071230-&&-cellular response to amino acid stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0001741-&&-XY body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0000791-&&-euchromatin-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005720-&&-nuclear heterochromatin|molecular_function-&-1&-GO:0003886-&&-DNA (cytosine-5-)-methyltransferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding	G:9606:DNMT3A	DNMT3A	TRUE	KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer	DNMT3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT3A	0.38406148	0.25141243	62	4	FALSE	DNMT3A	DNMT3A	175.45	0	61	0	0.73270837	FALSE	1	DNMT3A	137468	0.0689129
787964	taxon:9606	2.48668662	4.05E-04	178493	1902	pterin-4 alpha-carbinolamine dehydratase 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006559-&&-L-phenylalanine catabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008124-&&-4-alpha-hydroxytetrahydrobiopterin dehydratase activity-%%-GO:0004505-&&-phenylalanine 4-monooxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding	G:9606:PCBD1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	PCBD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBD1	0.40214154	0.06019871	61	4	FALSE	PCBD1	PCBD1	131.3898305	0	60	0	0.7522189	FALSE	1	PCBD1	494946	0.04068743
788209	taxon:9606	2.45879943	2.37E-04	178072	1902	radixin	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0032487-&&-regulation of Rap protein signal transduction-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:1903392-&&-negative regulation of adherens junction organization-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0030033-&&-microvillus assembly-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:1902966-&&-positive regulation of protein localization to early endosome-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0008361-&&-regulation of cell size-%%-GO:0032231-&&-regulation of actin filament bundle assembly-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0034111-&&-negative regulation of homotypic cell-cell adhesion-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:1902115-&&-regulation of organelle assembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0045176-&&-apical protein localization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0010737-&&-protein kinase A signaling|cellular_component-&-1&-GO:0032420-&&-stereocilium-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0051286-&&-cell tip-%%-GO:0005902-&&-microvillus-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0030315-&&-T-tubule-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030027-&&-lamellipodium-%%-GO:0001726-&&-ruffle-%%-GO:0043209-&&-myelin sheath-%%-GO:0030175-&&-filopodium-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003779-&&-actin binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:RDX			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	RDX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RDX	0.40670255	0.0989071	61	4	FALSE	RDX	RDX	131.2459016	0	61	0	0.75686676	FALSE	0	RDX	295180	0.03855325
788509	taxon:9606	2.42634315	1.21E-04	177528	1902	SOS Ras/Rac guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0003209-&&-cardiac atrium morphogenesis-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:1904693-&&-midbrain morphogenesis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0051057-&&-positive regulation of small GTPase mediated signal transduction-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:2000973-&&-regulation of pro-B cell differentiation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0060021-&&-palate development-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0001942-&&-hair follicle development-%%-GO:0003344-&&-pericardium morphogenesis-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0007296-&&-vitellogenesis-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:SOS1	SOS1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SOS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOS1	0.41214286	0.23670368	61	4	FALSE	SOS1	SOS1	166.559322	0	60	0	0.76227614	FALSE	1	SOS1	194366	0.04622325
788548	taxon:9606	2.49015283	3.17E-04	177462	1902	sterol regulatory element binding transcription factor 2	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0090370-&&-negative regulation of cholesterol efflux-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0055098-&&-response to low-density lipoprotein particle-%%-GO:0072368-&&-regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009267-&&-cellular response to starvation-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032937-&&-SREBP-SCAP-Insig complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070888-&&-E-box binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000247-&&-C-8 sterol isomerase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SREBF2	SREBF2	TRUE		SREBF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SREBF2	0.40158178	0.10987726	61	4	FALSE	SREBF2	SREBF2	128.3898305	0	60	0	0.7516412	FALSE	1	SREBF2	339192	0.04009921
788816	taxon:9606	2.54246101	8.72E-05	176818	1902	ubiquitin conjugating enzyme E2 B	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0051026-&&-chiasma assembly-%%-GO:0006301-&&-postreplication repair-%%-GO:0007288-&&-sperm axoneme assembly-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0070076-&&-histone lysine demethylation-%%-GO:0033128-&&-negative regulation of histone phosphorylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010845-&&-positive regulation of reciprocal meiotic recombination-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0070193-&&-synaptonemal complex organization-%%-GO:0045141-&&-meiotic telomere clustering-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0050821-&&-protein stabilization-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0033503-&&-HULC complex-%%-GO:0001741-&&-XY body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0005524-&&-ATP binding	G:9606:UBE2B			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2B	0.3933197	0.14377557	61	4	FALSE	UBE2B	UBE2B	117.8305085	0	60	0	0.74292317	FALSE	1	UBE2B	154018	0.0408083
788823	taxon:9606	2.62265637	1.78E-04	176810	1902	ubiquitin conjugating enzyme E2 H	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2H			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2H	0.3812928	0.0251315	61	4	FALSE	UBE2H	UBE2H	76.66101695	0	60	0	0.72955727	FALSE	1	UBE2H	206286	0.03221698
789257	taxon:9606	2.37750118	8.39E-05	175885	1902	eukaryotic translation initiation factor 3 subunit H	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3H			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa03013-&&-RNA transport	EIF3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3H	0.42060968	0.21693989	61	4	FALSE	EIF3H	EIF3H	201.5737705	0	61	0	0.77041647	FALSE	0	EIF3H	192802	0.05145289
789558	taxon:9606	2.49188593	2.40E-04	175191	1902	RB1 inducible coiled-coil 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0007507-&&-heart development-%%-GO:0061709-&&-reticulophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0061723-&&-glycophagy-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0030242-&&-pexophagy-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006914-&&-autophagy-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0001889-&&-liver development-%%-GO:0000422-&&-mitophagy-%%-GO:0046330-&&-positive regulation of JNK cascade|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:1990316-&&-ATG1/ULK1 kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0005515-&&-protein binding	G:9606:RB1CC1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04211-&&-Longevity regulating pathway	RB1CC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RB1CC1	0.40130248	0.04863388	61	4	FALSE	RB1CC1	RB1CC1	116.5409836	0	61	0	0.75135234	FALSE	0	RB1CC1	292870	0.03639622
789633	taxon:9606	2.47234914	1.11E-04	175026	1902	TRAF family member associated NFKB activator	gene	biological_process-&-1&-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2000158-&&-positive regulation of ubiquitin-specific protease activity-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:1903003-&&-positive regulation of protein deubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0035800-&&-deubiquitinase activator activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TANK			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	TANK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TANK	0.40447362	0.1320865	61	4	FALSE	TANK	TANK	138.9322034	0	60	0	0.75460848	FALSE	1	TANK	170124	0.04192012
789763	taxon:9606	2.41815031	2.15E-04	174740	1902	B-cell receptor-associated protein 31	gene	biological_process-&-1&-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0070973-&&-protein localization to endoplasmic reticulum exit site-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:1903071-&&-positive regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1904154-&&-positive regulation of retrograde protein transport, ER to cytosol-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005784-&&-Sec61 translocon complex-%%-GO:0005829-&&-cytosol-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:BCAP31			KEGG-&-1&-hsa05165-&&-Human papillomavirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	BCAP31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAP31	0.41353922	0.10286382	61	4	FALSE	BCAP31	BCAP31	162.9491525	0	60	0	0.76364162	FALSE	1	BCAP31	327878	0.0445367
789980	taxon:9606	2.38459115	1.36E-04	174197	1902	5'-3' exoribonuclease 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006396-&&-RNA processing-%%-GO:0021766-&&-hippocampus development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000738-&&-DNA catabolic process, exonucleolytic-%%-GO:0006397-&&-mRNA processing-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0030182-&&-neuron differentiation-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0016049-&&-cell growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0008409-&&-5'-3' exonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004518-&&-nuclease activity-%%-GO:0004534-&&-5'-3' exoribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001147-&&-transcription termination site sequence-specific DNA binding	G:9606:XRN2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03018-&&-RNA degradation	XRN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XRN2	0.4193591	0.1863388	61	4	FALSE	XRN2	XRN2	258.147541	0	61	0	0.76923481	FALSE	0	XRN2	225194	0.06649015
789983	taxon:9606	2.40901213	8.95E-05	174185	1902	coatomer protein complex subunit gamma 1	gene	biological_process-&-1&-GO:0051683-&&-establishment of Golgi localization-%%-GO:0072384-&&-organelle transport along microtubule-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:COPG1				COPG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPG1	0.41510791	0.17708942	61	4	FALSE	COPG1	COPG1	207.8474576	0	60	0	0.76516464	FALSE	1	COPG1	203356	0.05568878
790098	taxon:9606	2.60154404	1.33E-04	173878	1902	arginine demethylase and lysine hydroxylase	gene	biological_process-&-1&-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:0048821-&&-erythrocyte development-%%-GO:0007507-&&-heart development-%%-GO:0070079-&&-histone H4-R3 demethylation-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0070078-&&-histone H3-R2 demethylation-%%-GO:0001822-&&-kidney development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0008380-&&-RNA splicing-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0006397-&&-mRNA processing-%%-GO:0043654-&&-recognition of apoptotic cell-%%-GO:0042116-&&-macrophage activation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0018395-&&-peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0033749-&&-histone demethylase activity (H4-R3 specific)-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0033746-&&-histone demethylase activity (H3-R2 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0004872-&&-receptor activity-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070815-&&-peptidyl-lysine 5-dioxygenase activity-%%-GO:0003723-&&-RNA binding	G:9606:JMJD6				JMJD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JMJD6	0.38438711	0.11338399	61	4	FALSE	JMJD6	JMJD6	134.6779661	0	60	0	0.73307599	FALSE	1	JMJD6	216454	0.05328411
790465	taxon:9606	2.3882149	7.14E-05	172780	1902	GRB10 interacting GYF protein 2	gene	biological_process-&-1&-GO:0061157-&&-mRNA destabilization-%%-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007631-&&-feeding behavior-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0016441-&&-posttranscriptional gene silencing-%%-GO:0050881-&&-musculoskeletal movement-%%-GO:0009791-&&-post-embryonic development|cellular_component-&-1&-GO:1990635-&&-proximal dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:GIGYF2				GIGYF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIGYF2	0.41872279	0.13934426	61	4	FALSE	GIGYF2	GIGYF2	209.7213115	0	61	0	0.76863085	FALSE	0	GIGYF2	182890	0.05437555
790653	taxon:9606	2.479124	8.91E-05	171638	1902	PAF1 homolog, Paf1/RNA polymerase II complex component	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0016584-&&-nucleosome positioning-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0031062-&&-positive regulation of histone methylation-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:PAF1				PAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAF1	0.40336829	0.21092896	61	4	FALSE	PAF1	PAF1	177.5901639	0	61	0	0.75347933	FALSE	0	PAF1	193258	0.05380527
790672	taxon:9606	2.51867024	1.35E-04	171534	1902	homeodomain interacting protein kinase 2	gene	biological_process-&-1&-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007628-&&-adult walking behavior-%%-GO:0030578-&&-PML body organization-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030182-&&-neuron differentiation-%%-GO:0060235-&&-lens induction in camera-type eye-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0010842-&&-retina layer formation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001654-&&-eye development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0016605-&&-PML body-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046790-&&-virion binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:HIPK2			KEGG-&-1&-hsa04218-&&-Cellular senescence	HIPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIPK2	0.39703491	0.13091759	61	4	FALSE	HIPK2	HIPK2	135.9661017	0	60	0	0.74688829	FALSE	1	HIPK2	185720	0.04493992
790826	taxon:9606	2.47943911	1.20E-04	171070	1902	COP9 signalosome subunit 7A	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS7A				COPS7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS7A	0.40331702	0.20655738	61	4	FALSE	COPS7A	COPS7A	153.2131148	0	61	0	0.75342682	FALSE	0	COPS7A	183862	0.04671981
790951	taxon:9606	2.34567512	2.90E-04	170627	1902	DnaJ heat shock protein family (Hsp40) member B11	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJB11			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJB11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB11	0.4263165	0.09672131	61	4	FALSE	DNAJB11	DNAJB11	198.6229508	0	61	0	0.77572081	FALSE	0	DNAJB11	419874	0.04835766
791131	taxon:9606	2.59870805	1.15E-04	169944	1902	myosin VC	gene	cellular_component-&-1&-GO:0016459-&&-myosin complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003774-&&-motor activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MYO5C				MYO5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO5C	0.3848066	0.24480874	61	4	FALSE	MYO5C	MYO5C	104.5737705	0	61	0	0.73354866	FALSE	0	MYO5C	142726	0.04117408
791340	taxon:9606	2.49157082	2.94E-04	169097	1902	THO complex 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0016973-&&-poly(A)+ mRNA export from nucleus-%%-GO:0048666-&&-neuron development-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0048699-&&-generation of neurons|cellular_component-&-1&-GO:0000445-&&-THO complex part of transcription export complex-%%-GO:0000346-&&-transcription export complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000347-&&-THO complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:THOC2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome	THOC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THOC2	0.40135323	0.10983607	61	4	FALSE	THOC2	THOC2	166.7213115	0	61	0	0.75140486	FALSE	0	THOC2	386420	0.05193046
792851	taxon:9606	2.43390578	3.37E-04	181271	1902	erb-b2 receptor tyrosine kinase 4	gene	biological_process-&-1&-GO:0007595-&&-lactation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007399-&&-nervous system development-%%-GO:0016477-&&-cell migration-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0021551-&&-central nervous system morphogenesis-%%-GO:0021889-&&-olfactory bulb interneuron differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:2000366-&&-positive regulation of STAT protein import into nucleus-%%-GO:0061026-&&-cardiac muscle tissue regeneration-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0007507-&&-heart development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0007165-&&-signal transduction-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0045165-&&-cell fate commitment|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043235-&&-receptor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:ERBB4	ERBB4	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	ERBB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERBB4	0.41086225	0.12857978	61	4	FALSE	ERBB4	ERBB4	148.7457627	0	60	0	0.7610157	FALSE	1	ERBB4	447598	0.0417543
793080	taxon:9606	2.45296991	1.18E-04	180795	1902	general transcription factor IIIC subunit 1	gene	biological_process-&-1&-GO:0009304-&&-tRNA transcription-%%-GO:0042797-&&-tRNA transcription from RNA polymerase III promoter-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0006384-&&-transcription initiation from RNA polymerase III promoter-%%-GO:0042791-&&-5S class rRNA transcription from RNA polymerase III type 1 promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009303-&&-rRNA transcription|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000127-&&-transcription factor TFIIIC complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001002-&&-RNA polymerase III type 1 promoter sequence-specific DNA binding-%%-GO:0001007-&&-transcription factor activity, RNA polymerase III transcription factor binding-%%-GO:0000995-&&-transcription factor activity, core RNA polymerase III binding-%%-GO:0001003-&&-RNA polymerase III type 2 promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:GTF3C1				GTF3C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF3C1	0.40766909	0.13551913	61	4	FALSE	GTF3C1	GTF3C1	186.5409836	0	61	0	0.75783835	FALSE	0	GTF3C1	216570	0.05422997
793275	taxon:9606	2.45643611	1.25E-04	180384	1902	histone cluster 1 H1 family member b	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0050821-&&-protein stabilization-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006325-&&-chromatin organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0071169-&&-establishment of protein localization to chromatin|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1B				HIST1H1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1B	0.40709384	0.16830601	61	4	FALSE	HIST1H1B	HIST1H1B	222.4262295	0	61	0	0.75726065	FALSE	0	HIST1H1B	264360	0.06501774
788115	taxon:9606	2.40192217	1.94E-04	178212	1902	protein tyrosine phosphatase, non-receptor type 12	gene	biological_process-&-1&-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0042246-&&-tissue regeneration-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005925-&&-focal adhesion-%%-GO:0002102-&&-podosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:PTPN12				PTPN12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN12	0.41633322	0.11412429	60	4	FALSE	PTPN12	PTPN12	144.1333333	0	60	0	0.76634631	FALSE	0	PTPN12	285598	0.03842358
788122	taxon:9606	2.46226564	2.44E-04	178207	1902	protein tyrosine phosphatase, receptor type C	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0001915-&&-negative regulation of T cell mediated cytotoxicity-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0048539-&&-bone marrow development-%%-GO:0042100-&&-B cell proliferation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0050857-&&-positive regulation of antigen receptor-mediated signaling pathway-%%-GO:0048864-&&-stem cell development-%%-GO:0051607-&&-defense response to virus-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0030217-&&-T cell differentiation-%%-GO:0006933-&&-negative regulation of cell adhesion involved in substrate-bound cell migration-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0002378-&&-immunoglobulin biosynthetic process-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:2000473-&&-positive regulation of hematopoietic stem cell migration|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRC			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04660-&&-T cell receptor signaling pathway	PTPRC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRC	0.40613002	0.14761041	60	4	FALSE	PTPRC	PTPRC	142.5	0	59	0	0.75628906	FALSE	1	PTPRC	320664	0.0422644
788195	taxon:9606	2.42823381	1.95E-04	178097	1902	RB binding protein 6, ubiquitin ligase	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0048568-&&-embryonic organ development-%%-GO:0006397-&&-mRNA processing-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0061053-&&-somite development-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RBBP6				RBBP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP6	0.41182196	0.06666667	60	4	FALSE	RBBP6	RBBP6	144.4	0	60	0	0.76196103	FALSE	0	RBBP6	293264	0.04013823
788215	taxon:9606	2.28107767	1.39E-04	145299	1902	TMX2-CTNND1 readthrough (NMD candidate)	gene		G:9606:TMX2-CTNND1				TMX2-CTNND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMX2-CTNND1	0.43838928	0.16575923	60	4	FALSE	TMX2-CTNND1	TMX2-CTNND1	252.7068966	0	59	0	0.78648705	FALSE	1	TMX2-CTNND1	336494	0.0557975
788572	taxon:9606	2.52245155	1.32E-04	177412	1902	TATA-box binding protein associated factor 10	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0051101-&&-regulation of DNA binding-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000125-&&-PCAF complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TAF10			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF10	0.39643973	0.15910466	60	4	FALSE	TAF10	TAF10	125.9827586	0	59	0	0.74625807	FALSE	1	TAF10	181642	0.04139178
788637	taxon:9606	2.49692768	9.35E-05	177272	1902	ubiquitin conjugating enzyme E2 A	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006281-&&-DNA repair-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0006301-&&-postreplication repair-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0033503-&&-HULC complex-%%-GO:0001741-&&-XY body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2A			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2A	0.40049218	0.10889292	60	4	FALSE	UBE2A	UBE2A	140.2758621	0	59	0	0.75051205	FALSE	1	UBE2A	168524	0.04415661
788789	taxon:9606	2.40743658	9.99E-05	160508	1902	tubulin beta 2B class IIb	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0001764-&&-neuron migration-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:TUBB2B			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB2B	0.41537958	0.14519774	60	4	FALSE	TUBB2B	TUBB2B	214.7666667	0	60	0	0.76542724	FALSE	0	TUBB2B	232620	0.0576775
789145	taxon:9606	2.53537104	1.04E-04	176115	1902	ring finger protein 8	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0007286-&&-spermatid development-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0045190-&&-isotype switching-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043486-&&-histone exchange-%%-GO:0070535-&&-histone H2A K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0033522-&&-histone H2A ubiquitination-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:RNF8				RNF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF8	0.39441959	0.10647308	60	4	FALSE	RNF8	RNF8	131.0172414	0	59	0	0.74410483	FALSE	1	RNF8	168992	0.04464412
789163	taxon:9606	2.43437845	7.93E-05	176064	1902	ubiquitin specific peptidase 14	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0050920-&&-regulation of chemotaxis-%%-GO:1903070-&&-negative regulation of ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000502-&&-proteasome complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0008193-&&-tRNA guanylyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP14				USP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP14	0.41078247	0.27118644	60	4	FALSE	USP14	USP14	166.9833333	0	60	0	0.76093693	FALSE	0	USP14	155756	0.04689607
789700	taxon:9606	2.39609264	1.98E-04	174860	1902	hypoxia up-regulated 1	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1903382-&&-negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0002931-&&-response to ischemia-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1903298-&&-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005925-&&-focal adhesion-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding	G:9606:HYOU1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HYOU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HYOU1	0.41734613	0.10903955	60	4	FALSE	HYOU1	HYOU1	198.0166667	0	60	0	0.76731789	FALSE	0	HYOU1	321218	0.05208279
789731	taxon:9606	2.52812352	1.06E-04	174805	1902	mediator complex subunit 16	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:2000273-&&-positive regulation of receptor activity|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED16			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED16	0.39555029	0.27909605	60	4	FALSE	MED16	MED16	168.05	0	60	0	0.74531275	FALSE	0	MED16	240382	0.05580649
789986	taxon:9606	2.50764141	1.14E-04	174181	1902	heat shock protein family A (Hsp70) member 4 like	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:HSPA4L			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPA4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA4L	0.3987811	0.08870056	60	4	FALSE	HSPA4L	HSPA4L	123.5666667	0	60	0	0.74872643	FALSE	0	HSPA4L	183856	0.03994392
790054	taxon:9606	2.53600126	2.38E-04	173993	1902	ZW10 interacting kinetochore protein	gene	biological_process-&-1&-GO:0051649-&&-establishment of localization in cell-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000776-&&-kinetochore-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:ZWINT				ZWINT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZWINT	0.39432157	0.05021174	60	4	FALSE	ZWINT	ZWINT	90.06896552	0	59	0	0.74399979	FALSE	1	ZWINT	243628	0.0308237
790411	taxon:9606	2.54372144	2.12E-04	173086	1902	GABA type A receptor associated protein like 1	gene	biological_process-&-1&-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005622-&&-intracellular-%%-GO:0044297-&&-cell body-%%-GO:0032590-&&-dendrite membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005874-&&-microtubule-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005776-&&-autophagosome-%%-GO:0032839-&&-dendrite cytoplasm|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0050811-&&-GABA receptor binding-%%-GO:0030957-&&-Tat protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:GABARAPL1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	GABARAPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABARAPL1	0.39312481	0.11129944	60	4	FALSE	GABARAPL1	GABARAPL1	95.63333333	0	60	0	0.74271309	FALSE	0	GABARAPL1	261492	0.03306247
790621	taxon:9606	2.44367418	4.55E-05	171733	1902	eukaryotic translation initiation factor 3 subunit L	gene	biological_process-&-1&-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3L				EIF3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3L	0.40921986	0.30056497	60	4	FALSE	EIF3L	EIF3L	211.8166667	0	60	0	0.75938764	FALSE	0	EIF3L	130700	0.06053158
790659	taxon:9606	2.49078305	2.25E-04	171560	1902	GIT ArfGAP 1	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:GIT1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	GIT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIT1	0.40148017	0.07743497	60	4	FALSE	GIT1	GIT1	119.2241379	0	59	0	0.75153616	FALSE	1	GIT1	278494	0.03706923
790866	taxon:9606	2.52150622	1.90E-04	170838	1902	toll interacting protein	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0045321-&&-leukocyte activation-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0036010-&&-protein localization to endosome-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007165-&&-signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0045323-&&-interleukin-1 receptor complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016604-&&-nuclear body-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0045092-&&-interleukin-18 receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0035325-&&-Toll-like receptor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0032183-&&-SUMO binding-%%-GO:0005515-&&-protein binding-%%-GO:0005150-&&-interleukin-1, Type I receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0019900-&&-kinase binding	G:9606:TOLLIP			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway	TOLLIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOLLIP	0.39658835	0.07743497	60	4	FALSE	TOLLIP	TOLLIP	100.6206897	0	59	0	0.74641563	FALSE	1	TOLLIP	221632	0.03346113
791121	taxon:9606	2.39498976	1.28E-04	169963	1902	unc-45 myosin chaperone A	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0030154-&&-cell differentiation-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:UNC45A				UNC45A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC45A	0.41753832	0.10451977	60	4	FALSE	UNC45A	UNC45A	168.8166667	0	60	0	0.76750171	FALSE	0	UNC45A	260640	0.04429571
791366	taxon:9606	2.50449031	1.16E-04	168963	1902	KIAA1549	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:KIAA1549				KIAA1549	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA1549	0.39928284	0.1814882	60	4	FALSE	KIAA1549	KIAA1549	145.2758621	0	59	0	0.74925161	FALSE	1	KIAA1549	193056	0.04649764
791607	taxon:9606	2.56420356	9.55E-05	167843	1902	Smad nuclear interacting protein 1	gene	biological_process-&-1&-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNIP1				SNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNIP1	0.38998464	0.12372881	60	4	FALSE	SNIP1	SNIP1	124.15	0	60	0	0.73929941	FALSE	0	SNIP1	143970	0.04478114
792043	taxon:9606	2.48385064	1.86E-04	182695	1902	dystonin	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0048870-&&-cell motility-%%-GO:0030011-&&-maintenance of cell polarity-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0005882-&&-intermediate filament-%%-GO:0030056-&&-hemidesmosome-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005737-&&-cytoplasm-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031252-&&-cell leading edge-%%-GO:0031673-&&-H zone-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:DST				DST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DST	0.4026007	0.06327684	60	4	FALSE	DST	DST	141.9833333	0	60	0	0.75269156	FALSE	0	DST	271342	0.04380276
792047	taxon:9606	2.41578699	1.46E-04	182688	1902	BRCA2, DNA repair associated	gene	biological_process-&-1&-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0010225-&&-response to UV-C-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0008585-&&-female gonad development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:0001556-&&-oocyte maturation-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0000732-&&-strand displacement-%%-GO:0051298-&&-centrosome duplication-%%-GO:0000910-&&-cytokinesis-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007569-&&-cell aging-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0048478-&&-replication fork protection-%%-GO:0010165-&&-response to X-ray-%%-GO:0030097-&&-hemopoiesis-%%-GO:0007141-&&-male meiosis I-%%-GO:1990426-&&-mitotic recombination-dependent replication fork processing-%%-GO:0007420-&&-brain development-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0033593-&&-BRCA2-MAGE-D1 complex-%%-GO:0000800-&&-lateral element-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030141-&&-secretory granule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043015-&&-gamma-tubulin binding-%%-GO:0002020-&&-protease binding-%%-GO:0010484-&&-H3 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0010485-&&-H4 histone acetyltransferase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:BRCA2			KEGG-&-1&-hsa05212-&&-Pancreatic cancer-%%-hsa05224-&&-Breast cancer-%%-hsa03440-&&-Homologous recombination-%%-hsa05200-&&-Pathways in cancer-%%-hsa03460-&&-Fanconi anemia pathway	BRCA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRCA2	0.41394378	0.12542373	60	4	FALSE	BRCA2	BRCA2	162.8	0	60	0	0.7640355	FALSE	0	BRCA2	222564	0.04419857
792215	taxon:9606	2.42208918	1.22E-04	182397	1902	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	gene	biological_process-&-1&-GO:0003360-&&-brainstem development-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0021549-&&-cerebellum development-%%-GO:0009116-&&-nucleoside metabolic process-%%-GO:0046654-&&-tetrahydrofolate biosynthetic process-%%-GO:0046452-&&-dihydrofolate metabolic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010035-&&-response to inorganic substance-%%-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004643-&&-phosphoribosylaminoimidazolecarboxamide formyltransferase activity-%%-GO:0003937-&&-IMP cyclohydrolase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:ATIC			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism-%%-hsa01523-&&-Antifolate resistance	ATIC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATIC	0.41286671	0.10284332	60	4	FALSE	ATIC	ATIC	172.6551724	0	59	0	0.76298514	FALSE	1	ATIC	215198	0.0474446
792223	taxon:9606	2.62092327	2.12E-04	182385	1902	ATPase Na+/K+ transporting subunit beta 3	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:1903288-&&-positive regulation of potassium ion import-%%-GO:0006810-&&-transport-%%-GO:0010107-&&-potassium ion import-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:1903278-&&-positive regulation of sodium ion export from cell-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0050821-&&-protein stabilization-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086009-&&-membrane repolarization-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0005901-&&-caveola-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0051117-&&-ATPase binding	G:9606:ATP1B3			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04978-&&-Mineral absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1B3	0.38154494	0.0960452	60	4	FALSE	ATP1B3	ATP1B3	96.51666667	0	60	0	0.72984612	FALSE	0	ATP1B3	257638	0.04027023
792352	taxon:9606	2.44194107	1.23E-04	182173	1902	creatine kinase B	gene	biological_process-&-1&-GO:0021549-&&-cerebellum development-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0021762-&&-substantia nigra development-%%-GO:0016310-&&-phosphorylation-%%-GO:0030644-&&-cellular chloride ion homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005615-&&-extracellular space-%%-GO:0005739-&&-mitochondrion-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004111-&&-creatine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CKB			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	CKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKB	0.40951029	0.13389831	60	4	FALSE	CKB	CKB	194.2833333	0	60	0	0.75967649	FALSE	0	CKB	245996	0.05510165
792446	taxon:9606	2.28107767	1.39E-04	182010	1902	catenin delta 1	gene	biological_process-&-1&-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0007155-&&-cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0034332-&&-adherens junction organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005915-&&-zonula adherens-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding	G:9606:CTNND1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04520-&&-Adherens junction	CTNND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNND1	0.43838928	0.16575923	60	4	FALSE	CTNND1	CTNND1	252.7068966	0	59	0	0.78648705	FALSE	1	CTNND1	336494	0.0557975
792459	taxon:9606	2.55002363	8.13E-05	181980	1902	cytochrome c1	gene	biological_process-&-1&-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0033762-&&-response to glucagon|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005750-&&-mitochondrial respiratory chain complex III-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0045153-&&-electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity-%%-GO:0045155-&&-electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0020037-&&-heme binding	G:9606:CYC1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	CYC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYC1	0.39215323	0.20024198	60	4	FALSE	CYC1	CYC1	120.8793103	0	59	0	0.74166273	FALSE	1	CYC1	141114	0.04239287
792558	taxon:9606	2.47266425	1.23E-04	181818	1902	runt related transcription factor 2	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002063-&&-chondrocyte development-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001503-&&-ossification-%%-GO:0002076-&&-osteoblast development-%%-GO:0030217-&&-T cell differentiation-%%-GO:0040036-&&-regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0042487-&&-regulation of odontogenesis of dentin-containing tooth-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0001958-&&-endochondral ossification-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048469-&&-cell maturation-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0002051-&&-osteoblast fate commitment|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:RUNX2	RUNX2	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	RUNX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX2	0.40442207	0.18305085	60	4	FALSE	RUNX2	RUNX2	161.6333333	0	60	0	0.75455596	FALSE	0	RUNX2	190642	0.0485627
792619	taxon:9606	2.4512368	3.22E-04	181704	1902	enoyl-CoA hydratase 1	gene	biological_process-&-1&-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0016853-&&-isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:ECH1			KEGG-&-1&-hsa04146-&&-Peroxisome	ECH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECH1	0.40795732	0.06327684	60	4	FALSE	ECH1	ECH1	126.2166667	0	60	0	0.7581272	FALSE	0	ECH1	379532	0.03651414
792930	taxon:9606	2.49424925	2.74E-04	181120	1902	Fanconi anemia complementation group A	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0008584-&&-male gonad development-%%-GO:0008585-&&-female gonad development-%%-GO:0006461-&&-protein complex assembly-%%-GO:0045589-&&-regulation of regulatory T cell differentiation-%%-GO:2000348-&&-regulation of CD40 signaling pathway-%%-GO:0007140-&&-male meiosis-%%-GO:0006281-&&-DNA repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FANCA			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCA	0.40092224	0.09195402	60	4	FALSE	FANCA	FANCA	138.6896552	0	59	0	0.75095846	FALSE	1	FANCA	419784	0.04377077
792945	taxon:9606	2.48857728	2.19E-05	181101	1902	FAU, ubiquitin like and ribosomal protein S30 fusion	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:FAU			KEGG-&-1&-hsa03010-&&-Ribosome	FAU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAU	0.40183602	0.50225989	60	4	FALSE	FAU	FAU	210.9	0	60	0	0.75190379	FALSE	0	FAU	77762	0.06541046
792967	taxon:9606	2.51536159	2.26E-04	181074	1902	FK506 binding protein 1A	gene	biological_process-&-1&-GO:0022417-&&-protein maturation by protein folding-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0042110-&&-T cell activation-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0050776-&&-regulation of immune response-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:0042026-&&-protein refolding-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051280-&&-negative regulation of release of sequestered calcium ion into cytosol-%%-GO:1902991-&&-regulation of amyloid precursor protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0016020-&&-membrane-%%-GO:0014802-&&-terminal cisterna|molecular_function-&-1&-GO:0048185-&&-activin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0005527-&&-macrolide binding	G:9606:FKBP1A				FKBP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP1A	0.39755716	0.1107078	60	4	FALSE	FKBP1A	FKBP1A	106.1896552	0	59	0	0.74743974	FALSE	1	FKBP1A	247588	0.03475948
793094	taxon:9606	2.48763195	1.81E-04	180741	1902	GATA binding protein 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0048821-&&-erythrocyte development-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030222-&&-eosinophil differentiation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008584-&&-male gonad development-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0010725-&&-regulation of primitive erythrocyte differentiation-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0030220-&&-platelet formation-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0071733-&&-transcriptional activation by promoter-enhancer looping-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0030219-&&-megakaryocyte differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007596-&&-blood coagulation-%%-GO:0035854-&&-eosinophil fate commitment-%%-GO:0030221-&&-basophil differentiation-%%-GO:0010559-&&-regulation of glycoprotein biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030502-&&-negative regulation of bone mineralization|cellular_component-&-1&-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding	G:9606:GATA1				GATA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATA1	0.40198873	0.10621469	60	4	FALSE	GATA1	GATA1	136.8	0	60	0	0.75206134	FALSE	0	GATA1	248034	0.04234583
793282	taxon:9606	2.5142587	2.53E-05	180377	1902	histone cluster 1 H2B family member b	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2BB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BB	0.39773155	0.45875706	60	4	FALSE	HIST1H2BB	HIST1H2BB	238.4	0	60	0	0.74762355	FALSE	0	HIST1H2BB	105346	0.07764929
787141	taxon:9606	2.42429494	1.44E-04	179994	1902	DNA ligase 3	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006288-&&-base-excision repair, DNA ligation-%%-GO:0051301-&&-cell division-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0007049-&&-cell cycle-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0090298-&&-negative regulation of mitochondrial DNA replication-%%-GO:0033151-&&-V(D)J recombination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003910-&&-DNA ligase (ATP) activity	G:9606:LIG3			KEGG-&-1&-hsa03410-&&-Base excision repair	LIG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIG3	0.41249106	0.15195792	59	4	FALSE	LIG3	LIG3	222.1016949	0	59	0	0.76261751	FALSE	0	LIG3	292334	0.06119723
787315	taxon:9606	2.40979991	8.58E-05	179678	1902	transportin 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005929-&&-cilium-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:TNPO1				TNPO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNPO1	0.41497221	0.13408521	59	4	FALSE	TNPO1	TNPO1	210.2807018	0	58	0	0.76503335	FALSE	1	TNPO1	188762	0.05658426
787359	taxon:9606	2.477706	1.20E-04	163192	1902	argonaute 3, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0035068-&&-micro-ribonucleoprotein complex|molecular_function-&-1&-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:AGO3				AGO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO3	0.40359914	0.09877265	59	4	FALSE	AGO3	AGO3	146.5254237	0	59	0	0.75371567	FALSE	0	AGO3	183850	0.0444433
787368	taxon:9606	2.55585316	1.12E-04	179552	1902	MYB proto-oncogene, transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045624-&&-positive regulation of T-helper cell differentiation-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1904899-&&-positive regulation of hepatic stellate cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051574-&&-positive regulation of histone H3-K9 methylation-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000845-&&-positive regulation of testosterone secretion-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071636-&&-positive regulation of transforming growth factor beta production|cellular_component-&-1&-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:MYB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	MYB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYB	0.39125878	0.12507306	59	5	FALSE	MYB	MYB	129.6271186	0	59	0	0.74069114	FALSE	0	MYB	171990	0.04637055
787382	taxon:9606	2.40270994	1.38E-04	179521	1902	myosin light chain 6	gene	biological_process-&-1&-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0005903-&&-brush border-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016459-&&-myosin complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0016461-&&-unconventional myosin complex|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MYL6			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04530-&&-Tight junction-%%-hsa04921-&&-Oxytocin signaling pathway	MYL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL6	0.41619672	0.11689071	59	4	FALSE	MYL6	MYL6	207.9830509	0	59	0	0.76621501	FALSE	0	MYL6	248158	0.05547365
787444	taxon:9606	2.33905782	8.71E-05	179421	1902	MDM4, p53 regulator	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:0045023-&&-G0 to G1 transition-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:MDM4			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer	MDM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDM4	0.42752257	0.17919799	59	4	FALSE	MDM4	MDM4	217.4210526	0	58	0	0.7768237	FALSE	1	MDM4	198964	0.05228138
787513	taxon:9606	2.44729794	6.20E-05	179311	1902	Mov10 RISC complex RNA helicase	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035195-&&-gene silencing by miRNA|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:MOV10				MOV10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOV10	0.40861392	0.2238457	59	4	FALSE	MOV10	MOV10	228.2711864	0	59	0	0.75878368	FALSE	0	MOV10	160242	0.06528527
787619	taxon:9606	2.55853159	1.64E-04	179079	1902	NME/NM23 nucleoside diphosphate kinase 1	gene	biological_process-&-1&-GO:0006241-&&-CTP biosynthetic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006228-&&-UTP biosynthetic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0007399-&&-nervous system development-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0006183-&&-GTP biosynthetic process-%%-GO:0006897-&&-endocytosis-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0004550-&&-nucleoside diphosphate kinase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004536-&&-deoxyribonuclease activity-%%-GO:0042802-&&-identical protein binding	G:9606:NME1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME1	0.39084919	0.06829574	59	4	FALSE	NME1	NME1	108.2982456	0	58	0	0.74024474	FALSE	1	NME1	200196	0.03890078
787722	taxon:9606	2.4578541	8.22E-05	178875	1902	pinin, desmosome associated protein	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0030057-&&-desmosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0016020-&&-membrane-%%-GO:0035145-&&-exon-exon junction complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005198-&&-structural molecule activity	G:9606:PNN			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	PNN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNN	0.40685897	0.21491228	59	4	FALSE	PNN	PNN	199.1403509	0	58	0	0.75702432	FALSE	1	PNN	170488	0.05796369
788399	taxon:9606	2.47329447	2.10E-04	177737	1902	serine/threonine kinase 4	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0050821-&&-protein stabilization-%%-GO:0046621-&&-negative regulation of organ growth-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060215-&&-primitive hemopoiesis-%%-GO:0001841-&&-neural tube formation-%%-GO:0003157-&&-endocardium development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060800-&&-regulation of cell differentiation involved in embryonic placenta development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0035329-&&-hippo signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:STK4			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer	STK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK4	0.40431902	0.11340852	59	4	FALSE	STK4	STK4	129.8070175	0	58	0	0.75445092	FALSE	1	STK4	252962	0.03909971
788506	taxon:9606	2.49440681	1.63E-04	177539	1902	sorting nexin 2	gene	biological_process-&-1&-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0016050-&&-vesicle organization-%%-GO:0051259-&&-protein oligomerization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030905-&&-retromer, tubulation complex-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1990459-&&-transferrin receptor binding-%%-GO:1990460-&&-leptin receptor binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:SNX2			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX2	0.40089692	0.09711779	59	4	FALSE	SNX2	SNX2	122.7894737	0	58	0	0.7509322	FALSE	1	SNX2	221736	0.0384535
788606	taxon:9606	2.40964235	8.08E-05	177349	1902	treacle ribosome biogenesis factor 1	gene	biological_process-&-1&-GO:0001501-&&-skeletal system development-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:TCOF1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	TCOF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCOF1	0.41499935	0.15663355	59	4	FALSE	TCOF1	TCOF1	267.559322	0	59	0	0.76505961	FALSE	0	TCOF1	218876	0.07189611
788667	taxon:9606	2.44036553	1.03E-04	177224	1902	TIA1 cytotoxic granule associated RNA binding protein like 1	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0017145-&&-stem cell division-%%-GO:0006915-&&-apoptotic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007281-&&-germ cell development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:TIAL1				TIAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIAL1	0.40977468	0.14494448	59	4	FALSE	TIAL1	TIAL1	235.6949153	0	59	0	0.75993908	FALSE	0	TIAL1	237534	0.06675019
789104	taxon:9606	2.35812195	1.35E-04	176191	1902	eukaryotic translation initiation factor 2 subunit beta	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0008584-&&-male gonad development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0002176-&&-male germ cell proliferation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005850-&&-eukaryotic translation initiation factor 2 complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:EIF2S2			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2S2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2S2	0.42406628	0.1233197	59	4	FALSE	EIF2S2	EIF2S2	205.0677966	0	59	0	0.77364634	FALSE	0	EIF2S2	265238	0.05075096
789395	taxon:9606	2.47550024	1.31E-04	175579	1902	mediator complex subunit 14	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED14			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED14	0.40395876	0.27060199	59	4	FALSE	MED14	MED14	136.2542373	0	59	0	0.75408329	FALSE	0	MED14	214874	0.04113151
789902	taxon:9606	2.48038443	4.10E-05	174397	1902	influenza virus NS1A binding protein	gene	biological_process-&-1&-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009615-&&-response to virus-%%-GO:0008380-&&-RNA splicing-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm	G:9606:IVNS1ABP			KEGG-&-1&-hsa05164-&&-Influenza A	IVNS1ABP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IVNS1ABP	0.40316331	0.18295739	59	4	FALSE	IVNS1ABP	IVNS1ABP	175.5438597	0	58	0	0.75326926	FALSE	1	IVNS1ABP	93788	0.05351439
790169	taxon:9606	2.41862297	2.20E-04	173726	1902	CCR4-NOT transcription complex subunit 1	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0035195-&&-gene silencing by miRNA-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0010606-&&-positive regulation of cytoplasmic mRNA processing body assembly-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0030014-&&-CCR4-NOT complex-%%-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0030015-&&-CCR4-NOT core complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0003723-&&-RNA binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity	G:9606:CNOT1			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT1	0.41345841	0.08942139	59	4	FALSE	CNOT1	CNOT1	168.1694915	0	59	0	0.76356284	FALSE	0	CNOT1	300476	0.04592942
790834	taxon:9606	2.60501024	1.49E-04	171011	1902	mediator complex subunit 31	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0060173-&&-limb development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0016592-&&-mediator complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED31				MED31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED31	0.38387565	0.06487434	59	4	FALSE	MED31	MED31	91.49152542	0	59	0	0.73249829	FALSE	0	MED31	189004	0.03642985
790898	taxon:9606	2.42208918	8.84E-05	170742	1902	leucyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006438-&&-valyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0006429-&&-leucyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004823-&&-leucine-tRNA ligase activity-%%-GO:0004832-&&-valine-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:LARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	LARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARS	0.41286671	0.18468732	59	4	FALSE	LARS	LARS	192.1186441	0	59	0	0.76298514	FALSE	0	LARS	196578	0.05282338
790947	taxon:9606	2.47487002	1.47E-04	170629	1902	ubiquitin interaction motif containing 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070537-&&-histone H2A K63-linked deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:UIMC1			KEGG-&-1&-hsa03440-&&-Homologous recombination	UIMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UIMC1	0.40406162	0.13383986	59	4	FALSE	UIMC1	UIMC1	160.440678	0	59	0	0.75418833	FALSE	0	UIMC1	229904	0.04843566
791050	taxon:9606	2.49188593	2.90E-04	170233	1902	BTG3 associated nuclear protein	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding	G:9606:BANP				BANP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BANP	0.40130248	0.0820802	59	4	FALSE	BANP	BANP	137.0526316	0	58	0	0.75135234	FALSE	1	BANP	399844	0.04281733
791239	taxon:9606	2.55585316	9.21E-05	169562	1902	catenin beta like 1	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0016445-&&-somatic diversification of immunoglobulins-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000974-&&-Prp19 complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:CTNNBL1			KEGG-&-1&-hsa03040-&&-Spliceosome	CTNNBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNBL1	0.39125878	0.07205514	59	4	FALSE	CTNNBL1	CTNNBL1	161.4736842	0	58	0	0.74069114	FALSE	1	CTNNBL1	184562	0.05754136
791274	taxon:9606	2.39404443	1.72E-04	169413	1902	exportin 5	gene	biological_process-&-1&-GO:0035281-&&-pre-miRNA export from nucleus-%%-GO:1900370-&&-positive regulation of RNA interference-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0031047-&&-gene silencing by RNA|cellular_component-&-1&-GO:0042565-&&-RNA nuclear export complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0090631-&&-pre-miRNA transporter activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:XPO5			KEGG-&-1&-hsa03013-&&-RNA transport	XPO5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO5	0.41770319	0.08883694	59	4	FALSE	XPO5	XPO5	188.1355932	0	59	0	0.76765926	FALSE	0	XPO5	304546	0.04941313
791568	taxon:9606	2.54057035	2.07E-04	167977	1902	coiled-coil domain containing 33	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC33				CCDC33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC33	0.3936124	0.04734074	59	4	FALSE	CCDC33	CCDC33	88.55932203	0	59	0	0.74323828	FALSE	0	CCDC33	236280	0.03068614
791655	taxon:9606	2.46746494	6.04E-05	167567	1902	chromatin licensing and DNA replication factor 1	gene	biological_process-&-1&-GO:0000076-&&-DNA replication checkpoint-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0033262-&&-regulation of nuclear cell cycle DNA replication-%%-GO:0006260-&&-DNA replication-%%-GO:0030174-&&-regulation of DNA-dependent DNA replication initiation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:CDT1				CDT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDT1	0.40527425	0.17606516	59	4	FALSE	CDT1	CDT1	174.8947368	0	58	0	0.75542251	FALSE	1	CDT1	130558	0.05187174
791849	taxon:9606	2.38726958	4.48E-05	182977	1902	ATP binding cassette subfamily F member 1	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006954-&&-inflammatory response-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity	G:9606:ABCF1				ABCF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCF1	0.4188886	0.23027469	59	4	FALSE	ABCF1	ABCF1	235.4915254	0	59	0	0.7687884	FALSE	0	ABCF1	136066	0.061119
792234	taxon:9606	2.68961714	6.14E-04	182374	1902	ATPase H+/K+ transporting alpha subunit	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0006810-&&-transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0008900-&&-hydrogen:potassium-exchanging ATPase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:ATP4A			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04971-&&-Gastric acid secretion	ATP4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP4A	0.37180013	0.03007519	59	4	FALSE	ATP4A	ATP4A	64.26315789	0	58	0	0.71839714	FALSE	1	ATP4A	814856	0.03281819
792556	taxon:9606	2.66724437	1.81E-04	181816	1902	RUNX1 translocation partner 1	gene	biological_process-&-1&-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:RUNX1T1	RUNX1T1	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	RUNX1T1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUNX1T1	0.37491878	0.08834586	59	5	FALSE	RUNX1T1	RUNX1T1	85.8245614	0	58	0	0.72212594	FALSE	1	RUNX1T1	208982	0.03986573
793049	taxon:9606	2.32535056	1.52E-04	180833	1902	gelsolin	gene	biological_process-&-1&-GO:0051014-&&-actin filament severing-%%-GO:0030041-&&-actin filament polymerization-%%-GO:1903906-&&-regulation of plasma membrane raft polarization-%%-GO:0042246-&&-tissue regeneration-%%-GO:1903923-&&-positive regulation of protein processing in phagocytic vesicle-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0051593-&&-response to folic acid-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0060271-&&-cilium assembly-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001269-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:1903689-&&-regulation of wound healing, spreading of epidermal cells-%%-GO:0051693-&&-actin filament capping-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:1902174-&&-positive regulation of keratinocyte apoptotic process-%%-GO:0014891-&&-striated muscle atrophy-%%-GO:0031648-&&-protein destabilization-%%-GO:0051127-&&-positive regulation of actin nucleation-%%-GO:0097017-&&-renal protein absorption-%%-GO:1903909-&&-regulation of receptor clustering-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0007568-&&-aging-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0042989-&&-sequestering of actin monomers-%%-GO:0071801-&&-regulation of podosome assembly-%%-GO:0045010-&&-actin nucleation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903903-&&-regulation of establishment of T cell polarity-%%-GO:0090527-&&-actin filament reorganization|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016528-&&-sarcoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0002102-&&-podosome-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0030027-&&-lamellipodium-%%-GO:0001726-&&-ruffle-%%-GO:0030478-&&-actin cap-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0045159-&&-myosin II binding	G:9606:GSN			KEGG-&-1&-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04810-&&-Regulation of actin cytoskeleton	GSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSN	0.43004269	0.17475161	59	4	FALSE	GSN	GSN	217.0169492	0	59	0	0.77910824	FALSE	0	GSN	281102	0.05116725
793074	taxon:9606	2.41673231	1.68E-04	180807	1902	general transcription factor IIF subunit 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005674-&&-transcription factor TFIIF complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0000991-&&-transcription factor activity, core RNA polymerase II binding	G:9606:GTF2F2			KEGG-&-1&-hsa03022-&&-Basal transcription factors	GTF2F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2F2	0.41378186	0.12844612	59	4	FALSE	GTF2F2	GTF2F2	143.5614035	0	58	0	0.76387795	FALSE	1	GTF2F2	249100	0.03901922
793310	taxon:9606	2.38947534	1.36E-04	180332	1902	high density lipoprotein binding protein	gene	biological_process-&-1&-GO:0008203-&&-cholesterol metabolic process-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0034364-&&-high-density lipoprotein particle|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:HDLBP				HDLBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDLBP	0.41850191	0.10169492	59	4	FALSE	HDLBP	HDLBP	193.6440678	0	59	0	0.76842078	FALSE	0	HDLBP	238632	0.05043676
787316	taxon:9606	2.41310856	7.14E-05	179673	1902	keratin 1	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0042730-&&-fibrinolysis-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0001867-&&-complement activation, lectin pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0045095-&&-keratin filament-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0004872-&&-receptor activity	G:9606:KRT1				KRT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT1	0.41440324	0.22323049	58	4	FALSE	KRT1	KRT1	234.1896552	0	58	0	0.76448191	FALSE	0	KRT1	192416	0.06356472
787360	taxon:9606	2.55002363	6.17E-05	163191	1902	argonaute 4, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0008584-&&-male gonad development-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007140-&&-male meiosis-%%-GO:0007130-&&-synaptonemal complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000932-&&-P-body-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0035068-&&-micro-ribonucleoprotein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:AGO4				AGO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO4	0.39215323	0.09255898	58	4	FALSE	AGO4	AGO4	137.3275862	0	58	0	0.74166273	FALSE	0	AGO4	125970	0.04844761
787626	taxon:9606	2.50307232	2.58E-04	179067	1902	nitric oxide synthase 3	gene	biological_process-&-1&-GO:0001974-&&-blood vessel remodeling-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0014740-&&-negative regulation of muscle hyperplasia-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0009408-&&-response to heat-%%-GO:0030324-&&-lung development-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0014806-&&-smooth muscle hyperplasia-%%-GO:0003100-&&-regulation of systemic arterial blood pressure by endothelin-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0003057-&&-regulation of the force of heart contraction by chemical signal-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0001525-&&-angiogenesis-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0042311-&&-vasodilation-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0043542-&&-endothelial cell migration|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0046870-&&-cadmium ion binding-%%-GO:0010181-&&-FMN binding-%%-GO:0050661-&&-NADP binding-%%-GO:0034618-&&-arginine binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004517-&&-nitric-oxide synthase activity-%%-GO:0003785-&&-actin monomer binding-%%-GO:0020037-&&-heme binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:NOS3	NOS3	TRUE	KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	NOS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOS3	0.39950903	0.07272727	58	4	FALSE	NOS3	NOS3	109.7142857	0	57	0	0.74948795	FALSE	1	NOS3	255086	0.03506857
787815	taxon:9606	2.51662203	2.39E-04	178754	1902	protein kinase C gamma	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007635-&&-chemosensory behavior-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007611-&&-learning or memory-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032095-&&-regulation of response to food-%%-GO:0032425-&&-positive regulation of mismatch repair-%%-GO:0060384-&&-innervation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0043278-&&-response to morphine-%%-GO:0048265-&&-response to pain-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030168-&&-platelet activation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0097060-&&-synaptic membrane|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004698-&&-calcium-dependent protein kinase C activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKCG			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04510-&&-Focal adhesion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04970-&&-Salivary secretion	PRKCG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCG	0.39735804	0.04350649	58	4	FALSE	PRKCG	PRKCG	103.4642857	0	57	0	0.74722966	FALSE	1	PRKCG	267408	0.03403576
787998	taxon:9606	2.42082874	1.84E-04	178435	1902	pyruvate dehydrogenase (lipoamide) beta	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006086-&&-acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0045254-&&-pyruvate dehydrogenase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004739-&&-pyruvate dehydrogenase (acetyl-transferring) activity-%%-GO:0005515-&&-protein binding-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0004738-&&-pyruvate dehydrogenase activity	G:9606:PDHB			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	PDHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDHB	0.41308168	0.09675325	58	4	FALSE	PDHB	PDHB	185.625	0	57	0	0.76319521	FALSE	1	PDHB	281858	0.05097206
788010	taxon:9606	2.50338743	8.64E-05	178402	1902	phosphoribosylformylglycinamidine synthase	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004642-&&-phosphoribosylformylglycinamidine synthase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:PFAS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	PFAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFAS	0.39945875	0.11191773	58	4	FALSE	PFAS	PFAS	138.7758621	0	58	0	0.74943543	FALSE	0	PFAS	139796	0.04424701
788177	taxon:9606	2.45501812	1.09E-04	178121	1902	RAP1A, member of RAS oncogene family	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0030033-&&-microvillus assembly-%%-GO:0097421-&&-liver regeneration-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0015031-&&-protein transport-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:1905451-&&-positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:0097327-&&-response to antineoplastic agent-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0035690-&&-cellular response to drug-%%-GO:2000301-&&-negative regulation of synaptic vesicle exocytosis-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0007165-&&-signal transduction-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0010976-&&-positive regulation of neuron projection development|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032045-&&-guanyl-nucleotide exchange factor complex-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005769-&&-early endosome-%%-GO:0005770-&&-late endosome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0017016-&&-Ras GTPase binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0017034-&&-Rap guanyl-nucleotide exchange factor activity-%%-GO:0003924-&&-GTPase activity	G:9606:RAP1A			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04530-&&-Tight junction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04972-&&-Pancreatic secretion	RAP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP1A	0.40732897	0.09220779	58	4	FALSE	RAP1A	RAP1A	144.4821429	0	57	0	0.75749698	FALSE	1	RAP1A	182952	0.04208477
788328	taxon:9606	2.55144163	2.34E-04	177878	1902	spermidine/spermine N1-acetyltransferase 1	gene	biological_process-&-1&-GO:0032918-&&-spermidine acetylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0006596-&&-polyamine biosynthetic process-%%-GO:0046208-&&-spermine catabolic process-%%-GO:0009447-&&-putrescine catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004145-&&-diamine N-acetyltransferase activity-%%-GO:0019809-&&-spermidine binding-%%-GO:0005515-&&-protein binding	G:9606:SAT1			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04216-&&-Ferroptosis	SAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAT1	0.39193528	0.05454545	58	4	FALSE	SAT1	SAT1	105.2678571	0	57	0	0.7414264	FALSE	1	SAT1	252590	0.0370947
788395	taxon:9606	2.54639987	1.88E-04	177747	1902	signal transducer and activator of transcription 6	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002829-&&-negative regulation of type 2 immune response-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0048295-&&-positive regulation of isotype switching to IgE isotypes-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0002296-&&-T-helper 1 cell lineage commitment-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1902170-&&-cellular response to reactive nitrogen species-%%-GO:0060443-&&-mammary gland morphogenesis|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:STAT6			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04658-&&-Th1 and Th2 cell differentiation	STAT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT6	0.3927113	0.0961039	58	4	FALSE	STAT6	STAT6	122.0535714	0	57	0	0.74226669	FALSE	1	STAT6	232154	0.04263619
788735	taxon:9606	2.3666299	2.02E-04	177065	1902	tuberous sclerosis 2	gene	biological_process-&-1&-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0061024-&&-membrane organization-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0043276-&&-anoikis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0008104-&&-protein localization-%%-GO:0006897-&&-endocytosis-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0001843-&&-neural tube closure-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:1901525-&&-negative regulation of macromitophagy-%%-GO:0016032-&&-viral process-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007507-&&-heart development-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway|cellular_component-&-1&-GO:0033596-&&-TSC1-TSC2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0031267-&&-small GTPase binding	G:9606:TSC2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa04150-&&-mTOR signaling pathway	TSC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC2	0.42254177	0.12038717	58	4	FALSE	TSC2	TSC2	186.3103448	0	58	0	0.77222835	FALSE	0	TSC2	291498	0.04675474
789218	taxon:9606	2.50464787	1.42E-04	175978	1902	basic helix-loop-helix family member e40	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043426-&&-MRF binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:BHLHE40			KEGG-&-1&-hsa04710-&&-Circadian rhythm	BHLHE40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BHLHE40	0.39925772	0.10779221	58	4	FALSE	BHLHE40	BHLHE40	131.1071429	0	57	0	0.74922536	FALSE	1	BHLHE40	202142	0.0419123
789248	taxon:9606	2.47959666	1.55E-04	175898	1902	suppressor of cytokine signaling 1	gene	biological_process-&-1&-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0010534-&&-regulation of activation of JAK2 kinase activity-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042512-&&-negative regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0040008-&&-regulation of growth-%%-GO:0042518-&&-negative regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007259-&&-JAK-STAT cascade|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0019210-&&-kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0019901-&&-protein kinase binding	G:9606:SOCS1	SOCS1	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation	SOCS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS1	0.4032914	0.18935269	58	4	FALSE	SOCS1	SOCS1	138.137931	0	58	0	0.75340056	FALSE	0	SOCS1	244824	0.04225166
789288	taxon:9606	2.54813298	7.79E-05	175823	1902	zinc finger RANBP2-type containing 2	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ZRANB2				ZRANB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZRANB2	0.3924442	0.12467532	58	4	FALSE	ZRANB2	ZRANB2	127.8571429	0	57	0	0.74197784	FALSE	1	ZRANB2	137034	0.04478677
789735	taxon:9606	2.66692926	1.94E-04	174798	1902	poly(ADP-ribose) polymerase 2	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0006281-&&-DNA repair-%%-GO:0006273-&&-lagging strand elongation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003910-&&-DNA ligase (ATP) activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:PARP2			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis	PARP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP2	0.37496308	0.13551119	58	4	FALSE	PARP2	PARP2	147.2931035	0	58	0	0.72217846	FALSE	0	PARP2	352160	0.0694458
789898	taxon:9606	2.43264534	1.68E-04	174404	1902	RANBP2-type and C3HC4-type zinc finger containing 1	gene	biological_process-&-1&-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016032-&&-viral process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0097039-&&-protein linear polyubiquitination-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0060546-&&-negative regulation of necroptotic process|cellular_component-&-1&-GO:0071797-&&-LUBAC complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RBCK1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	RBCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBCK1	0.41107513	0.15519481	58	4	FALSE	RBCK1	RBCK1	157.625	0	57	0	0.76122578	FALSE	1	RBCK1	237678	0.04422175
790143	taxon:9606	2.53017173	1.04E-04	173782	1902	sirtuin 2	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006476-&&-protein deacetylation-%%-GO:0051301-&&-cell division-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:1900226-&&-negative regulation of NLRP3 inflammasome complex assembly-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0070446-&&-negative regulation of oligodendrocyte progenitor proliferation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:1900425-&&-negative regulation of defense response to bacterium-%%-GO:0006914-&&-autophagy-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0016458-&&-gene silencing-%%-GO:0031641-&&-regulation of myelination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0021762-&&-substantia nigra development-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0071219-&&-cellular response to molecule of bacterial origin-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0045843-&&-negative regulation of striated muscle tissue development-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:1900195-&&-positive regulation of oocyte maturation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:2000777-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia-%%-GO:0090042-&&-tubulin deacetylation-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0006342-&&-chromatin silencing-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:0045836-&&-positive regulation of meiotic nuclear division-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045087-&&-innate immune response-%%-GO:0051987-&&-positive regulation of attachment of spindle microtubules to kinetochore-%%-GO:0051775-&&-response to redox state-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:1901026-&&-ripoptosome assembly involved in necroptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0061433-&&-cellular response to caloric restriction-%%-GO:0044242-&&-cellular lipid catabolic process-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0016575-&&-histone deacetylation-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005874-&&-microtubule-%%-GO:0043209-&&-myelin sheath-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043219-&&-lateral loop-%%-GO:0030496-&&-midbody-%%-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0030426-&&-growth cone-%%-GO:0044224-&&-juxtaparanode region of axon-%%-GO:0043204-&&-perikaryon-%%-GO:0033270-&&-paranode region of axon-%%-GO:0005694-&&-chromosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0097386-&&-glial cell projection-%%-GO:0005814-&&-centriole-%%-GO:0005737-&&-cytoplasm-%%-GO:0033010-&&-paranodal junction-%%-GO:0005829-&&-cytosol-%%-GO:0072687-&&-meiotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046970-&&-NAD-dependent histone deacetylase activity (H4-K16 specific)-%%-GO:0042903-&&-tubulin deacetylase activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0034979-&&-NAD-dependent protein deacetylase activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033558-&&-protein deacetylase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0017136-&&-NAD-dependent histone deacetylase activity	G:9606:SIRT2				SIRT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT2	0.39523009	0.12337662	58	4	FALSE	SIRT2	SIRT2	169.1785714	0	57	0	0.74497138	FALSE	1	SIRT2	182980	0.05701522
790274	taxon:9606	2.46636206	2.13E-04	173466	1902	dicer 1, ribonuclease III	gene	biological_process-&-1&-GO:0014040-&&-positive regulation of Schwann cell differentiation-%%-GO:0033168-&&-conversion of ds siRNA to ss siRNA involved in RNA interference-%%-GO:0036404-&&-conversion of ds siRNA to ss siRNA-%%-GO:0030423-&&-targeting of mRNA for destruction involved in RNA interference-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0021675-&&-nerve development-%%-GO:0032290-&&-peripheral nervous system myelin formation-%%-GO:0010626-&&-negative regulation of Schwann cell proliferation-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035087-&&-siRNA loading onto RISC involved in RNA interference|cellular_component-&-1&-GO:0033167-&&-ARC complex-%%-GO:0030424-&&-axon-%%-GO:0016442-&&-RISC complex-%%-GO:0005829-&&-cytosol-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0035197-&&-siRNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004525-&&-ribonuclease III activity-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:DICER1	DICER1	TRUE	KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	DICER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DICER1	0.40545547	0.11103896	58	4	FALSE	DICER1	DICER1	165.4285714	0	57	0	0.75560632	FALSE	1	DICER1	292024	0.04891419
790305	taxon:9606	2.55868914	3.95E-05	173368	1902	anti-silencing function 1A histone chaperone	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006281-&&-DNA repair-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0031936-&&-negative regulation of chromatin silencing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:ASF1A				ASF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASF1A	0.39082512	0.36479129	58	4	FALSE	ASF1A	ASF1A	224.8793103	0	58	0	0.74021848	FALSE	0	ASF1A	107970	0.07979876
790912	taxon:9606	2.44651016	1.77E-04	170713	1902	histone deacetylase 7	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis-%%-GO:0070932-&&-histone H3 deacetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0033613-&&-activating transcription factor binding	G:9606:HDAC7			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC7	0.40874549	0.17792208	58	4	FALSE	HDAC7	HDAC7	169.7321429	0	57	0	0.75891497	FALSE	1	HDAC7	233702	0.04852995
791083	taxon:9606	2.34189381	4.82E-05	170113	1902	N-acetyltransferase 10	gene	biological_process-&-1&-GO:0002101-&&-tRNA wobble cytosine modification-%%-GO:0051391-&&-tRNA acetylation-%%-GO:0000154-&&-rRNA modification-%%-GO:1904812-&&-rRNA acetylation involved in maturation of SSU-rRNA-%%-GO:0008150-&&-biological_process-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0030686-&&-90S preribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005697-&&-telomerase holoenzyme complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:1990883-&&-rRNA cytidine N-acetyltransferase activity-%%-GO:0008080-&&-N-acetyltransferase activity-%%-GO:0051392-&&-tRNA N-acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:NAT10			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NAT10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAT10	0.42700484	0.27586207	58	4	FALSE	NAT10	NAT10	313.7068966	0	58	0	0.77635103	FALSE	0	NAT10	138348	0.07570147
791385	taxon:9606	2.60532535	9.23E-05	168851	1902	regulation of nuclear pre-mRNA domain containing 1B	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0010564-&&-regulation of cell cycle process-%%-GO:0070940-&&-dephosphorylation of RNA polymerase II C-terminal domain-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0005515-&&-protein binding	G:9606:RPRD1B				RPRD1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPRD1B	0.38382922	0.15245009	58	4	FALSE	RPRD1B	RPRD1B	106.7586207	0	58	0	0.73244577	FALSE	0	RPRD1B	141538	0.04240133
791709	taxon:9606	2.53221995	1.75E-04	167268	1902	kelch repeat and BTB domain containing 7	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KBTBD7				KBTBD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KBTBD7	0.3949104	0.04718693	58	4	FALSE	KBTBD7	KBTBD7	112.0517241	0	58	0	0.74463001	FALSE	0	KBTBD7	205364	0.03771697
791720	taxon:9606	2.51898535	1.13E-04	167204	1902	RAB1B, member RAS oncogene family	gene	biological_process-&-1&-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0015031-&&-protein transport-%%-GO:0019068-&&-virion assembly-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:1903020-&&-positive regulation of glycoprotein metabolic process-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding	G:9606:RAB1B			KEGG-&-1&-hsa05134-&&-Legionellosis	RAB1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB1B	0.39698524	0.13974592	58	4	FALSE	RAB1B	RAB1B	117.8793103	0	58	0	0.74683578	FALSE	0	RAB1B	167630	0.03896267
791813	taxon:9606	2.44020797	9.11E-05	166755	1902	tubulin beta 6 class V	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003674-&&-molecular_function-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBB6			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB6	0.40980114	0.10828796	58	4	FALSE	TUBB6	TUBB6	191.6034483	0	58	0	0.75996534	FALSE	0	TUBB6	216366	0.05448001
791899	taxon:9606	2.36836301	1.40E-04	182914	1902	adaptor related protein complex 1 beta 1 subunit	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:AP1B1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1B1	0.42223257	0.1487013	58	4	FALSE	AP1B1	AP1B1	226.3035714	0	57	0	0.7719395	FALSE	1	AP1B1	266438	0.05686102
792145	taxon:9606	2.60296203	1.61E-04	182520	1902	actinin alpha 2	gene	biological_process-&-1&-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0055013-&&-cardiac muscle cell development-%%-GO:0030035-&&-microspike assembly-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0045214-&&-sarcomere organization-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0007155-&&-cell adhesion-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2001137-&&-positive regulation of endocytic recycling-%%-GO:0051695-&&-actin filament uncapping-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:2001259-&&-positive regulation of cation channel activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0086097-&&-phospholipase C-activating angiotensin-activated signaling pathway-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0002576-&&-platelet degranulation-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0031143-&&-pseudopodium-%%-GO:0005925-&&-focal adhesion-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0070080-&&-titin Z domain binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0031432-&&-titin binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0030375-&&-thyroid hormone receptor coactivator activity-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0042802-&&-identical protein binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0051373-&&-FATZ binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005178-&&-integrin binding-%%-GO:0030274-&&-LIM domain binding-%%-GO:0044325-&&-ion channel binding	G:9606:ACTN2			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ACTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTN2	0.38417771	0.07402597	58	4	FALSE	ACTN2	ACTN2	89.05357143	0	57	0	0.73283966	FALSE	1	ACTN2	171132	0.03524026
792435	taxon:9606	2.44241374	1.15E-04	182030	1902	cleavage stimulation factor subunit 2	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071920-&&-cleavage body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSTF2			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CSTF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTF2	0.40943104	0.11615245	58	4	FALSE	CSTF2	CSTF2	145.8275862	0	58	0	0.75959771	FALSE	0	CSTF2	191724	0.04157694
792693	taxon:9606	2.54892075	2.35E-04	181554	1902	DNA damage inducible transcript 3	gene	biological_process-&-1&-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0043620-&&-regulation of DNA-templated transcription in response to stress-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006983-&&-ER overload response-%%-GO:0032792-&&-negative regulation of CREB transcription factor activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0042594-&&-response to starvation-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0044324-&&-regulation of transcription involved in anterior/posterior axis specification-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:2000016-&&-negative regulation of determination of dorsal identity-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:1990442-&&-intrinsic apoptotic signaling pathway in response to nitrosative stress-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0005829-&&-cytosol-%%-GO:1990617-&&-CHOP-ATF4 complex-%%-GO:1990622-&&-CHOP-ATF3 complex-%%-GO:0035976-&&-transcription factor AP-1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0036488-&&-CHOP-C/EBP complex-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008140-&&-cAMP response element binding protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:DDIT3			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DDIT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDIT3	0.39232291	0.16363636	58	4	FALSE	DDIT3	DDIT3	119.7321429	0	57	0	0.74184654	FALSE	1	DDIT3	292642	0.0419991
792940	taxon:9606	2.64502915	3.32E-05	181111	1902	bromodomain PHD finger transcription factor	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0007492-&&-endoderm development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0009611-&&-response to wounding-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016589-&&-NURF complex-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:BPTF				BPTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BPTF	0.37806767	0.33030853	58	4	FALSE	BPTF	BPTF	209.6206897	0	58	0	0.72582848	FALSE	0	BPTF	98984	0.09164242
792991	taxon:9606	2.39278399	2.20E-04	181038	1902	flotillin 2	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0050821-&&-protein stabilization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0034114-&&-regulation of heterotypic cell-cell adhesion-%%-GO:1903905-&&-positive regulation of establishment of T cell polarity-%%-GO:0001765-&&-membrane raft assembly-%%-GO:0044860-&&-protein localization to plasma membrane raft-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0034139-&&-regulation of toll-like receptor 3 signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:1902992-&&-negative regulation of amyloid precursor protein catabolic process-%%-GO:0045661-&&-regulation of myoblast differentiation|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016600-&&-flotillin complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0031982-&&-vesicle-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005901-&&-caveola-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0002020-&&-protease binding	G:9606:FLOT2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	FLOT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLOT2	0.41792322	0.13732607	58	4	FALSE	FLOT2	FLOT2	176.2586207	0	58	0	0.76786933	FALSE	0	FLOT2	309178	0.04623187
787198	taxon:9606	2.58011659	2.25E-04	179888	1902	MAGE family member A11	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAGEA11				MAGEA11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA11	0.38757938	0.04107744	57	4	FALSE	MAGEA11	MAGEA11	89.18181818	0	56	0	0.73664723	FALSE	1	MAGEA11	230376	0.03357594
787449	taxon:9606	2.52686308	1.56E-04	179415	1902	myocyte enhancer factor 2A	gene	biological_process-&-1&-GO:0055005-&&-ventricular cardiac myofibril assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0000002-&&-mitochondrial genome maintenance-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0070375-&&-ERK5 cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0061337-&&-cardiac conduction-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0048311-&&-mitochondrion distribution-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0007507-&&-heart development-%%-GO:0007517-&&-muscle organ development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048813-&&-dendrite morphogenesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:MEF2A	MEF2A	TRUE	KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MEF2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEF2A	0.3957476	0.1043771	57	4	FALSE	MEF2A	MEF2A	141.5272727	0	56	0	0.74552282	FALSE	1	MEF2A	223106	0.04719019
787699	taxon:9606	2.49298881	1.35E-04	178926	1902	phospholipase C gamma 2	gene	biological_process-&-1&-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030168-&&-platelet activation-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0030183-&&-B cell differentiation-%%-GO:0032959-&&-inositol trisphosphate biosynthetic process-%%-GO:0002316-&&-follicular B cell differentiation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0032237-&&-activation of store-operated calcium channel activity-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0004629-&&-phospholipase C activity	G:9606:PLCG2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04360-&&-Axon guidance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa05225-&&-Hepatocellular carcinoma	PLCG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCG2	0.40112494	0.22424242	57	4	FALSE	PLCG2	PLCG2	134.6545455	0	56	0	0.75116853	FALSE	1	PLCG2	188506	0.04213582
787720	taxon:9606	2.4742398	8.52E-05	178882	1902	exosome component 10	gene	biological_process-&-1&-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0071048-&&-nuclear retention of unspliced pre-mRNA at the site of transcription-%%-GO:0071028-&&-nuclear mRNA surveillance-%%-GO:0071035-&&-nuclear polyadenylation-dependent rRNA catabolic process-%%-GO:0009048-&&-dosage compensation by inactivation of X chromosome-%%-GO:0071034-&&-CUT catabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0006364-&&-rRNA processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0000176-&&-nuclear exosome (RNase complex)-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000178-&&-exosome (RNase complex)|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:EXOSC10			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC10	0.40416454	0.18383838	57	4	FALSE	EXOSC10	EXOSC10	212.7272727	0	56	0	0.75429337	FALSE	1	EXOSC10	161756	0.06375627
787751	taxon:9606	2.45659367	3.30E-04	178842	1902	POU class 2 homeobox 1	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:POU2F1				POU2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU2F1	0.40706773	0.12390572	57	4	FALSE	POU2F1	POU2F1	150.1818182	0	56	0	0.75723439	FALSE	1	POU2F1	362678	0.0440096
787836	taxon:9606	2.30408067	1.78E-04	178738	1902	mitogen-activated protein kinase 7	gene	biological_process-&-1&-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0070377-&&-negative regulation of ERK5 cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051344-&&-negative regulation of cyclic-nucleotide phosphodiesterase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007411-&&-axon guidance-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0007049-&&-cell cycle-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030821-&&-negative regulation of cAMP catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005524-&&-ATP binding	G:9606:MAPK7	MAPK7	TRUE	KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	MAPK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK7	0.43401258	0.13535354	57	4	FALSE	MAPK7	MAPK7	206.9636364	0	56	0	0.78265322	FALSE	1	MAPK7	283380	0.04722211
787867	taxon:9606	2.54041279	1.88E-04	178682	1902	presenilin 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006816-&&-calcium ion transport-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:0016485-&&-protein processing|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0030018-&&-Z disc-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004190-&&-aspartic-type endopeptidase activity	G:9606:PSEN2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease	PSEN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSEN2	0.39363681	0.08552189	57	4	FALSE	PSEN2	PSEN2	96.09090909	0	56	0	0.74326453	FALSE	1	PSEN2	226212	0.03327556
788088	taxon:9606	2.36820545	2.07E-04	178263	1902	profilin 1	gene	biological_process-&-1&-GO:1900029-&&-positive regulation of ruffle assembly-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0050821-&&-protein stabilization-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0051054-&&-positive regulation of DNA metabolic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005102-&&-receptor binding	G:9606:PFN1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05131-&&-Shigellosis	PFN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFN1	0.42226066	0.14814815	57	4	FALSE	PFN1	PFN1	247.7090909	0	56	0	0.77196576	FALSE	1	PFN1	306148	0.06221562
788235	taxon:9606	2.5637309	2.92E-04	178035	1902	SH3 domain containing GRB2 like 1, endophilin A2	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0007165-&&-signal transduction-%%-GO:0016191-&&-synaptic vesicle uncoating|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0042995-&&-cell projection-%%-GO:0045202-&&-synapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0002102-&&-podosome|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019902-&&-phosphatase binding	G:9606:SH3GL1			KEGG-&-1&-hsa04144-&&-Endocytosis	SH3GL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3GL1	0.39005654	0.12659933	57	4	FALSE	SH3GL1	SH3GL1	109	0	56	0	0.73937818	FALSE	1	SH3GL1	398740	0.0396941
788498	taxon:9606	2.42177407	1.05E-04	177545	1902	small nuclear ribonucleoprotein polypeptide F	gene	biological_process-&-1&-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0008380-&&-RNA splicing-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005683-&&-U7 snRNP-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNRPF			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPF	0.41292043	0.17669173	57	4	FALSE	SNRPF	SNRPF	205.4210526	0	57	0	0.76303766	FALSE	0	SNRPF	185716	0.05635315
788738	taxon:9606	2.50606586	1.72E-04	177066	1902	tuberous sclerosis 1	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0021766-&&-hippocampus development-%%-GO:0061024-&&-membrane organization-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0050821-&&-protein stabilization-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0006407-&&-rRNA export from nucleus-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0043379-&&-memory T cell differentiation-%%-GO:0046323-&&-glucose import-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0042552-&&-myelination-%%-GO:0032868-&&-response to insulin-%%-GO:0002250-&&-adaptive immune response-%%-GO:0050808-&&-synapse organization-%%-GO:0006813-&&-potassium ion transport-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0001822-&&-kidney development-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0030030-&&-cell projection organization-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0001843-&&-neural tube closure-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016242-&&-negative regulation of macroautophagy|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0033596-&&-TSC1-TSC2 complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0032794-&&-GTPase activating protein binding	G:9606:TSC1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection	TSC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC1	0.39903181	0.07340067	57	4	FALSE	TSC1	TSC1	133.7272727	0	56	0	0.74898902	FALSE	1	TSC1	217870	0.04304339
788793	taxon:9606	2.39246888	1.09E-04	176883	1902	proline rich coiled-coil 2A	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PRRC2A				PRRC2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRRC2A	0.41797827	0.14786967	57	4	FALSE	PRRC2A	PRRC2A	272.4561404	0	57	0	0.76792185	FALSE	0	PRRC2A	229718	0.07104943
789131	taxon:9606	2.38695447	1.99E-04	176141	1902	Wiskott-Aldrich syndrome like	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0061024-&&-membrane organization-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030050-&&-vesicle transport along actin filament-%%-GO:0016050-&&-vesicle organization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0051653-&&-spindle localization-%%-GO:2000601-&&-positive regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:2000370-&&-positive regulation of clathrin-dependent endocytosis-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0009617-&&-response to bacterium-%%-GO:1903526-&&-negative regulation of membrane tubulation-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006900-&&-membrane budding-%%-GO:2000402-&&-negative regulation of lymphocyte migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030027-&&-lamellipodium-%%-GO:0005634-&&-nucleus-%%-GO:0030478-&&-actin cap|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0030695-&&-GTPase regulator activity	G:9606:WASL			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	WASL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WASL	0.41894389	0.11403509	57	4	FALSE	WASL	WASL	157.4912281	0	57	0	0.76884092	FALSE	0	WASL	301848	0.04082496
789140	taxon:9606	2.49346148	6.64E-05	176124	1902	TATA-box binding protein associated factor, RNA polymerase I subunit B	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0001189-&&-RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0070860-&&-RNA polymerase I core factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005668-&&-RNA polymerase transcription factor SL1 complex|molecular_function-&-1&-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0001187-&&-transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:TAF1B				TAF1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1B	0.40104891	0.33737374	57	4	FALSE	TAF1B	TAF1B	244.2363636	0	56	0	0.75108975	FALSE	1	TAF1B	167454	0.07604541
789166	taxon:9606	2.40113439	2.02E-04	176060	1902	ubiquitin specific peptidase 8	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0007032-&&-endosome organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0031313-&&-extrinsic component of endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP8			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04934-&&-Cushing syndrome	USP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP8	0.41646982	0.10639731	57	4	FALSE	USP8	USP8	176.7090909	0	56	0	0.7664776	FALSE	1	USP8	299736	0.04686279
789338	taxon:9606	2.59398141	6.32E-05	175705	1902	ATPase H+ transporting V0 subunit d1	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0007420-&&-brain development-%%-GO:0015992-&&-proton transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0090383-&&-phagosome acidification-%%-GO:0060271-&&-cilium assembly-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0016471-&&-vacuolar proton-transporting V-type ATPase complex-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0043679-&&-axon terminus-%%-GO:0016020-&&-membrane-%%-GO:0005769-&&-early endosome-%%-GO:0033179-&&-proton-transporting V-type ATPase, V0 domain-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008553-&&-hydrogen-exporting ATPase activity, phosphorylative mechanism-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:ATP6V0D1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V0D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V0D1	0.38550777	0.17481203	57	4	FALSE	ATP6V0D1	ATP6V0D1	122.245614	0	57	0	0.73433643	FALSE	0	ATP6V0D1	114226	0.04754591
789708	taxon:9606	2.51646447	1.84E-04	174848	1902	glutaredoxin 3	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0044571-&&-[2Fe-2S] cluster assembly-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0097428-&&-protein maturation by iron-sulfur cluster transfer|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0051536-&&-iron-sulfur cluster binding	G:9606:GLRX3				GLRX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLRX3	0.39738292	0.07340067	57	4	FALSE	GLRX3	GLRX3	136.0909091	0	56	0	0.74725592	FALSE	1	GLRX3	289984	0.04452581
789833	taxon:9606	2.34677801	9.43E-05	174546	1902	MAGE family member D2	gene	biological_process-&-1&-GO:0007565-&&-female pregnancy-%%-GO:0070294-&&-renal sodium ion absorption-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAGED2				MAGED2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGED2	0.42611615	0.18671679	57	4	FALSE	MAGED2	MAGED2	236.1578947	0	57	0	0.775537	FALSE	0	MAGED2	195648	0.05726966
790200	taxon:9606	2.50386009	1.13E-04	173653	1902	trinucleotide repeat containing 6B	gene	biological_process-&-1&-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:TNRC6B				TNRC6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNRC6B	0.39938334	0.14786967	57	4	FALSE	TNRC6B	TNRC6B	162.6491228	0	57	0	0.74935665	FALSE	0	TNRC6B	197086	0.05178232
790486	taxon:9606	2.48117221	1.97E-04	172723	1902	TRAF3 interacting protein 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0001822-&&-kidney development-%%-GO:0021532-&&-neural tube patterning-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0001738-&&-morphogenesis of a polarized epithelium-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:1901621-&&-negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0042073-&&-intraciliary transport-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0036064-&&-ciliary basal body-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0005929-&&-cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0030992-&&-intraciliary transport particle B-%%-GO:0005813-&&-centrosome-%%-GO:0097542-&&-ciliary tip-%%-GO:0097546-&&-ciliary base|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:TRAF3IP1				TRAF3IP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF3IP1	0.40303531	0.08082707	57	4	FALSE	TRAF3IP1	TRAF3IP1	143.5964912	0	57	0	0.75313797	FALSE	0	TRAF3IP1	305750	0.04396715
790594	taxon:9606	2.71514101	8.37E-05	172021	1902	M-phase phosphoprotein 8	gene	biological_process-&-1&-GO:0044030-&&-regulation of DNA methylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0000788-&&-nuclear nucleosome-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:MPHOSPH8				MPHOSPH8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPHOSPH8	0.368305	0.13265993	57	4	FALSE	MPHOSPH8	MPHOSPH8	150	0	56	0	0.71414316	FALSE	1	MPHOSPH8	150134	0.07953459
790649	taxon:9606	2.7047424	1.21E-04	171670	1902	small glutamine rich tetratricopeptide repeat containing beta	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SGTB				SGTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGTB	0.36972098	0.02255639	57	4	FALSE	SGTB	SGTB	55.77192982	0	57	0	0.71587627	FALSE	0	SGTB	125068	0.02988042
791040	taxon:9606	2.39861352	1.65E-04	170274	1902	coiled-coil-helix-coiled-coil-helix domain containing 3	gene	biological_process-&-1&-GO:0042407-&&-cristae formation-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0007007-&&-inner mitochondrial membrane organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0061617-&&-MICOS complex|molecular_function-&-1&-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:CHCHD3				CHCHD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHCHD3	0.41690751	0.07769424	57	4	FALSE	CHCHD3	CHCHD3	201.2982456	0	57	0	0.76689775	FALSE	0	CHCHD3	366668	0.05302442
791091	taxon:9606	2.59303608	1.22E-04	170086	1902	MRG domain binding protein	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0016573-&&-histone acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MRGBP				MRGBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRGBP	0.38564832	0.14974937	57	4	FALSE	MRGBP	MRGBP	122.9122807	0	57	0	0.73449399	FALSE	0	MRGBP	197472	0.04745926
791153	taxon:9606	2.67291634	1.24E-04	169876	1902	O-sialoglycoprotein endopeptidase	gene	biological_process-&-1&-GO:0002949-&&-tRNA threonylcarbamoyladenosine modification|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0000408-&&-EKC/KEOPS complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0061711-&&-N(6)-L-threonylcarbamoyladenine synthase	G:9606:OSGEP				OSGEP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSGEP	0.37412319	0.07205387	57	4	FALSE	OSGEP	OSGEP	73.92727273	0	56	0	0.72118061	FALSE	1	OSGEP	143656	0.03535208
791287	taxon:9606	2.41893808	1.69E-04	169338	1902	WD repeat domain 48	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:1902525-&&-regulation of protein monoubiquitination-%%-GO:0043588-&&-skin development-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007338-&&-single fertilization-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0048568-&&-embryonic organ development-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0016032-&&-viral process-%%-GO:0035264-&&-multicellular organism growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:WDR48			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	WDR48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR48	0.41340455	0.0877193	57	4	FALSE	WDR48	WDR48	156.7719298	0	57	0	0.76351032	FALSE	0	WDR48	244462	0.04283598
791357	taxon:9606	2.49456436	1.36E-04	169035	1902	ubiquitin conjugating enzyme E2 O	gene	biological_process-&-1&-GO:0006513-&&-protein monoubiquitination-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0070534-&&-protein K63-linked ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2O			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2O	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2O	0.4008716	0.05387205	57	4	FALSE	UBE2O	UBE2O	145.0727273	0	56	0	0.75090594	FALSE	1	UBE2O	203808	0.04544029
791427	taxon:9606	2.49157082	1.15E-04	168686	1902	PTEN induced putative kinase 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0002082-&&-regulation of oxidative phosphorylation-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:2001171-&&-positive regulation of ATP biosynthetic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0072656-&&-maintenance of protein location in mitochondrion-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0033603-&&-positive regulation of dopamine secretion-%%-GO:0006950-&&-response to stress-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:1903751-&&-negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:1901727-&&-positive regulation of histone deacetylase activity-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0097237-&&-cellular response to toxic substance-%%-GO:0038203-&&-TORC2 signaling-%%-GO:1903384-&&-negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0000422-&&-mitophagy-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:1902803-&&-regulation of synaptic vesicle transport-%%-GO:0010310-&&-regulation of hydrogen peroxide metabolic process-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:1903147-&&-negative regulation of mitophagy-%%-GO:0032226-&&-positive regulation of synaptic transmission, dopaminergic-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:1903852-&&-positive regulation of cristae formation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0098779-&&-positive regulation of macromitophagy in response to mitochondrial depolarization-%%-GO:1903298-&&-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1903202-&&-negative regulation of oxidative stress-induced cell death-%%-GO:1904544-&&-positive regulation of free ubiquitin chain polymerization-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0016310-&&-phosphorylation-%%-GO:0099074-&&-mitochondrion to lysosome transport-%%-GO:0050821-&&-protein stabilization-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1902958-&&-positive regulation of mitochondrial electron transport, NADH to ubiquinone-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0090258-&&-negative regulation of mitochondrial fission-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:1900407-&&-regulation of cellular response to oxidative stress|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031932-&&-TORC2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097413-&&-Lewy body-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0000785-&&-chromatin-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0097449-&&-astrocyte projection|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0010857-&&-calcium-dependent protein kinase activity	G:9606:PINK1			KEGG-&-1&-hsa05012-&&-Parkinson disease-%%-hsa04137-&&-Mitophagy - animal	PINK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PINK1	0.40135323	0.11851852	57	4	FALSE	PINK1	PINK1	147.1818182	0	56	0	0.75140486	FALSE	1	PINK1	168868	0.04579984
791494	taxon:9606	2.50433276	2.06E-04	168389	1902	prolyl 3-hydroxylase 1	gene	biological_process-&-1&-GO:0032963-&&-collagen metabolic process-%%-GO:0019511-&&-peptidyl-proline hydroxylation-%%-GO:0060348-&&-bone development-%%-GO:0050821-&&-protein stabilization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0018126-&&-protein hydroxylation-%%-GO:0006457-&&-protein folding-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1901874-&&-negative regulation of post-translational protein modification|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0032991-&&-macromolecular complex-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0019797-&&-procollagen-proline 3-dioxygenase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005518-&&-collagen binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0003674-&&-molecular_function	G:9606:P3H1				P3H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P3H1	0.39930796	0.10964912	57	4	FALSE	P3H1	P3H1	134.7192983	0	57	0	0.74927787	FALSE	0	P3H1	274702	0.04282175
791525	taxon:9606	2.35213487	8.20E-05	168255	1902	importin 4	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006335-&&-DNA replication-dependent nucleosome assembly-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0006610-&&-ribosomal protein import into nucleus-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly|cellular_component-&-1&-GO:0034399-&&-nuclear periphery-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:IPO4				IPO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO4	0.42514569	0.13471178	57	4	FALSE	IPO4	IPO4	266.6666667	0	57	0	0.77464419	FALSE	0	IPO4	243182	0.06539896
792158	taxon:9606	2.39420199	1.71E-04	182507	1902	adenosine deaminase, RNA specific	gene	biological_process-&-1&-GO:0016553-&&-base conversion or substitution editing-%%-GO:0006382-&&-adenosine to inosine editing-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0098586-&&-cellular response to virus-%%-GO:0002566-&&-somatic diversification of immune receptors via somatic mutation-%%-GO:0009615-&&-response to virus-%%-GO:0061484-&&-hematopoietic stem cell homeostasis-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006397-&&-mRNA processing-%%-GO:1900369-&&-negative regulation of RNA interference-%%-GO:0051607-&&-defense response to virus-%%-GO:0060339-&&-negative regulation of type I interferon-mediated signaling pathway-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045087-&&-innate immune response-%%-GO:0035455-&&-response to interferon-alpha-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0044530-&&-supraspliceosomal complex-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003726-&&-double-stranded RNA adenosine deaminase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ADAR	ADAR	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05164-&&-Influenza A	ADAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAR	0.4176757	0.17239057	57	4	FALSE	ADAR	ADAR	265.4727273	0	56	0	0.767633	FALSE	1	ADAR	312496	0.06936749
792245	taxon:9606	2.70332441	1.68E-04	182356	1902	ATPase H+ transporting V1 subunit B1	gene	biological_process-&-1&-GO:0001503-&&-ossification-%%-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0006885-&&-regulation of pH-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0090383-&&-phagosome acidification-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0007588-&&-excretion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0045851-&&-pH reduction-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0015992-&&-proton transport|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005902-&&-microvillus-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016471-&&-vacuolar proton-transporting V-type ATPase complex-%%-GO:0098850-&&-extrinsic component of synaptic vesicle membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016820-&&-hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances-%%-GO:0032403-&&-protein complex binding-%%-GO:0015078-&&-hydrogen ion transmembrane transporter activity	G:9606:ATP6V1B1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1B1	0.36991491	0.03634085	57	4	FALSE	ATP6V1B1	ATP6V1B1	60.26315789	0	57	0	0.7161126	FALSE	0	ATP6V1B1	162872	0.03163632
792472	taxon:9606	2.50638097	2.20E-04	181965	1902	BCL2 associated agonist of cell death	gene	biological_process-&-1&-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:2000078-&&-positive regulation of type B pancreatic cell development-%%-GO:0046031-&&-ADP metabolic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0045471-&&-response to ethanol-%%-GO:0010918-&&-positive regulation of mitochondrial membrane potential-%%-GO:0046931-&&-pore complex assembly-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0007283-&&-spermatogenesis-%%-GO:0033133-&&-positive regulation of glucokinase activity-%%-GO:0071247-&&-cellular response to chromate-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0009749-&&-response to glucose-%%-GO:0032570-&&-response to progesterone-%%-GO:0043200-&&-response to amino acid-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0071396-&&-cellular response to lipid-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0042493-&&-response to drug-%%-GO:0060154-&&-cellular process regulating host cell cycle in response to virus-%%-GO:0006915-&&-apoptotic process-%%-GO:0060139-&&-positive regulation of apoptotic process by virus-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006007-&&-glucose catabolic process-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0033574-&&-response to testosterone-%%-GO:0044342-&&-type B pancreatic cell proliferation-%%-GO:0051592-&&-response to calcium ion-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045918-&&-negative regulation of cytolysis-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0034201-&&-response to oleic acid-%%-GO:0019050-&&-suppression by virus of host apoptotic process-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0008289-&&-lipid binding	G:9606:BAD	BAD	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04022-&&-cGMP-PKG signaling pathway	BAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAD	0.39898164	0.13157895	57	4	FALSE	BAD	BAD	131.8245614	0	57	0	0.74893651	FALSE	0	BAD	254130	0.04231266
792523	taxon:9606	2.49188593	2.18E-04	181855	1902	calcium/calmodulin dependent protein kinase II alpha	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0002931-&&-response to ischemia-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0046928-&&-regulation of neurotransmitter secretion-%%-GO:0030154-&&-cell differentiation-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:1902108-&&-regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007399-&&-nervous system development-%%-GO:0006816-&&-calcium ion transport-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0035254-&&-glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding	G:9606:CAMK2A			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04713-&&-Circadian entrainment-%%-hsa04217-&&-Necroptosis	CAMK2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK2A	0.40130248	0.08888889	57	4	FALSE	CAMK2A	CAMK2A	121.4363636	0	56	0	0.75135234	FALSE	1	CAMK2A	248630	0.03779011
792767	taxon:9606	2.53836458	5.24E-05	181408	1902	DNA methyltransferase 3 beta	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0014823-&&-response to activity-%%-GO:0031000-&&-response to caffeine-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042220-&&-response to cocaine-%%-GO:0009636-&&-response to toxic substance-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0032355-&&-response to estradiol-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0090116-&&-C-5 methylation of cytosine-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0042493-&&-response to drug-%%-GO:0033189-&&-response to vitamin A|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0003886-&&-DNA (cytosine-5-)-methyltransferase activity-%%-GO:0009008-&&-DNA-methyltransferase activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:DNMT3B			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer	DNMT3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNMT3B	0.39395444	0.17606516	57	4	FALSE	DNMT3B	DNMT3B	163.7017544	0	57	0	0.7436059	FALSE	0	DNMT3B	115430	0.05568788
792981	taxon:9606	2.56042225	1.96E-04	181050	1902	forkhead box S1	gene	biological_process-&-1&-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0001568-&&-blood vessel development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding	G:9606:FOXS1				FOXS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXS1	0.39056058	0.03571429	57	4	FALSE	FOXS1	FOXS1	94.42105263	0	57	0	0.73992963	FALSE	0	FOXS1	225718	0.03391813
792990	taxon:9606	2.38695447	1.99E-04	164654	1902	ankyrin repeat and SOCS box containing 15	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ASB15				ASB15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB15	0.41894389	0.11403509	57	4	FALSE	ASB15	ASB15	157.4912281	0	57	0	0.76884092	FALSE	0	ASB15	301848	0.04082496
793032	taxon:9606	2.42082874	5.39E-04	180867	1902	granulin precursor	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005764-&&-lysosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:GRN				GRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRN	0.41308168	0.03759398	57	4	FALSE	GRN	GRN	161.9298246	0	57	0	0.76319521	FALSE	0	GRN	590262	0.04452177
787306	taxon:9606	2.61666929	1.46E-04	179685	1902	kinesin family member 22	gene	biological_process-&-1&-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006281-&&-DNA repair-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000785-&&-chromatin-%%-GO:0016607-&&-nuclear speck-%%-GO:0005874-&&-microtubule-%%-GO:0005871-&&-kinesin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003777-&&-microtubule motor activity	G:9606:KIF22			KEGG-&-1&-hsa04914-&&-Progesterone-mediated oocyte maturation	KIF22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF22	0.38216522	0.05584416	56	4	FALSE	KIF22	KIF22	150.4642857	0	56	0	0.73055512	FALSE	0	KIF22	243790	0.06149737
787351	taxon:9606	2.68016386	2.02E-04	163227	1902	family with sequence similarity 9 member B	gene	biological_process-&-1&-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM9B				FAM9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM9B	0.37311152	0.02096436	56	4	FALSE	FAM9B	FAM9B	66.03703704	0	55	0	0.71997269	FALSE	1	FAM9B	200888	0.0322164
787475	taxon:9606	2.61635418	9.36E-05	179362	1902	midline 1	gene	biological_process-&-1&-GO:0007389-&&-pattern specification process-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0016740-&&-transferase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:MID1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	MID1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MID1	0.38221125	0.14046122	56	4	FALSE	MID1	MID1	129.3518519	0	55	0	0.73060764	FALSE	1	MID1	149966	0.05318549
787780	taxon:9606	2.44257129	2.63E-04	178799	1902	protein phosphatase 4 catalytic subunit	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0010569-&&-regulation of double-strand break repair via homologous recombination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0030289-&&-protein phosphatase 4 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004704-&&-NF-kappaB-inducing kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP4C			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway	PPP4C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP4C	0.40940463	0.16688312	56	4	FALSE	PPP4C	PPP4C	179.9464286	0	56	0	0.75957145	FALSE	0	PPP4C	393580	0.05119827
788199	taxon:9606	2.54167323	1.08E-04	178093	1902	RB transcriptional corepressor like 2	gene	biological_process-&-1&-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:RBL2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05165-&&-Human papillomavirus infection	RBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBL2	0.39344161	0.13441558	56	4	FALSE	RBL2	RBL2	124.6964286	0	56	0	0.74305446	FALSE	0	RBL2	153906	0.04281544
788236	taxon:9606	2.53773436	4.18E-04	178034	1902	SH3 domain containing GRB2 like 2, endophilin A1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0097484-&&-dendrite extension-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0016191-&&-synaptic vesicle uncoating-%%-GO:0031175-&&-neuron projection development-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:SH3GL2			KEGG-&-1&-hsa04144-&&-Endocytosis	SH3GL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3GL2	0.39405228	0.07127883	56	4	FALSE	SH3GL2	SH3GL2	93.98148148	0	55	0	0.74371094	FALSE	1	SH3GL2	433172	0.03220087
788306	taxon:9606	2.67937608	3.97E-04	177919	1902	retinoid X receptor beta	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004886-&&-9-cis retinoic acid receptor activity	G:9606:RXRB	RXRB	TRUE	KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa05226-&&-Gastric cancer-%%-hsa05222-&&-Small cell lung cancer	RXRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RXRB	0.37322122	0.05590496	56	4	FALSE	RXRB	RXRB	68.75925926	0	55	0	0.72010399	FALSE	1	RXRB	511226	0.03358073
788429	taxon:9606	2.3332283	4.85E-05	177687	1902	serine and arginine rich splicing factor 6	gene	biological_process-&-1&-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0061041-&&-regulation of wound healing-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:0045617-&&-negative regulation of keratinocyte differentiation-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032868-&&-response to insulin-%%-GO:0048025-&&-negative regulation of mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0036002-&&-pre-mRNA binding	G:9606:SRSF6			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03040-&&-Spliceosome	SRSF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRSF6	0.42859072	0.28766234	56	4	FALSE	SRSF6	SRSF6	286.8214286	0	56	0	0.77779528	FALSE	0	SRSF6	152888	0.0683191
788842	taxon:9606	2.61714196	2.09E-04	176771	1902	nuclear receptor subfamily 1 group H member 2	gene	biological_process-&-1&-GO:0045723-&&-positive regulation of fatty acid biosynthetic process-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0090108-&&-positive regulation of high-density lipoprotein particle assembly-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0032369-&&-negative regulation of lipid transport-%%-GO:0051006-&&-positive regulation of lipoprotein lipase activity-%%-GO:0060336-&&-negative regulation of interferon-gamma-mediated signaling pathway-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090187-&&-positive regulation of pancreatic juice secretion-%%-GO:0048550-&&-negative regulation of pinocytosis-%%-GO:0090340-&&-positive regulation of secretion of lysosomal enzymes-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0032376-&&-positive regulation of cholesterol transport-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046965-&&-retinoid X receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001133-&&-RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0034191-&&-apolipoprotein A-I receptor binding-%%-GO:0003677-&&-DNA binding	G:9606:NR1H2	NR1H2	TRUE	KEGG-&-1&-hsa04931-&&-Insulin resistance	NR1H2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR1H2	0.3820962	0.07407407	56	5	FALSE	NR1H2	NR1H2	99.92592593	0	55	0	0.73047634	FALSE	1	NR1H2	226982	0.0410396
788901	taxon:9606	2.52465732	1.13E-04	176645	1902	zeta chain of T-cell receptor associated protein kinase 70	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0002250-&&-adaptive immune response-%%-GO:0030217-&&-T cell differentiation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0070489-&&-T cell aggregation-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042113-&&-B cell activation-%%-GO:0042110-&&-T cell activation-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0072678-&&-T cell migration-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045059-&&-positive thymic T cell selection-%%-GO:0043366-&&-beta selection-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0045121-&&-membrane raft-%%-GO:0001772-&&-immunological synapse-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:ZAP70			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	ZAP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZAP70	0.39609336	0.22781272	56	4	FALSE	ZAP70	ZAP70	130.3518519	0	55	0	0.74589045	FALSE	1	ZAP70	161200	0.04361492
789078	taxon:9606	2.54025524	1.11E-04	176238	1902	CASP8 and FADD like apoptosis regulator	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1901740-&&-negative regulation of myoblast fusion-%%-GO:1903427-&&-negative regulation of reactive oxygen species biosynthetic process-%%-GO:0006508-&&-proteolysis-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006915-&&-apoptotic process-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0014866-&&-skeletal myofibril assembly-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:1903055-&&-positive regulation of extracellular matrix organization-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:1903944-&&-negative regulation of hepatocyte apoptotic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0060544-&&-regulation of necroptotic process-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:1903845-&&-negative regulation of cellular response to transforming growth factor beta stimulus-%%-GO:0033574-&&-response to testosterone-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0072126-&&-positive regulation of glomerular mesangial cell proliferation-%%-GO:0014842-&&-regulation of skeletal muscle satellite cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0031264-&&-death-inducing signaling complex-%%-GO:0097342-&&-ripoptosome-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CFLAR	CFLAR	TRUE	KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04217-&&-Necroptosis	CFLAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFLAR	0.39366123	0.11250874	56	4	FALSE	CFLAR	CFLAR	117.2592593	0	55	0	0.74329079	FALSE	1	CFLAR	160714	0.04047208
789386	taxon:9606	2.41058768	4.96E-05	175596	1902	aminoacyl tRNA synthetase complex interacting multifunctional protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009611-&&-response to wounding-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006935-&&-chemotaxis-%%-GO:0007155-&&-cell adhesion-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0017102-&&-methionyl glutamyl tRNA synthetase complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0051020-&&-GTPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:AIMP1				AIMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIMP1	0.4148366	0.22781272	56	4	FALSE	AIMP1	AIMP1	192.9814815	0	55	0	0.76490205	FALSE	1	AIMP1	121172	0.05198356
789546	taxon:9606	2.58641878	8.15E-05	175212	1902	lysine methyltransferase 2B	gene	biological_process-&-1&-GO:0007613-&&-memory-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0016458-&&-gene silencing-%%-GO:0009994-&&-oocyte differentiation-%%-GO:0030728-&&-ovulation-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0051569-&&-regulation of histone H3-K4 methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0080182-&&-histone H3-K4 trimethylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:KMT2B			KEGG-&-1&-hsa00310-&&-Lysine degradation	KMT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2B	0.38663499	0.13701299	56	4	FALSE	KMT2B	KMT2B	170.4642857	0	56	0	0.73559687	FALSE	0	KMT2B	171758	0.06498338
790319	taxon:9606	2.50653852	2.21E-04	173330	1902	ring finger and CHY zinc finger domain containing 1	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070987-&&-error-free translesion synthesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:RCHY1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04120-&&-Ubiquitin mediated proteolysis	RCHY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCHY1	0.39895657	0.07477289	56	4	FALSE	RCHY1	RCHY1	127.1666667	0	55	0	0.74891025	FALSE	1	RCHY1	280618	0.04101128
790413	taxon:9606	2.60611312	8.48E-05	173073	1902	EP300 interacting inhibitor of differentiation 1	gene	biological_process-&-1&-GO:0035065-&&-regulation of histone acetylation-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0007049-&&-cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0035034-&&-histone acetyltransferase regulator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0005515-&&-protein binding	G:9606:EID1				EID1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EID1	0.3837132	0.28051948	56	4	FALSE	EID1	EID1	203.5	0	56	0	0.73231448	FALSE	0	EID1	159224	0.08091496
790524	taxon:9606	2.68504805	1.36E-04	172607	1902	ADP ribosylation factor interacting protein 1	gene	biological_process-&-1&-GO:0050708-&&-regulation of protein secretion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding	G:9606:ARFIP1				ARFIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFIP1	0.37243281	0.05324675	56	4	FALSE	ARFIP1	ARFIP1	110	0	56	0	0.71915866	FALSE	0	ARFIP1	214260	0.05442977
790727	taxon:9606	2.49031038	1.64E-04	171373	1902	SH3 domain containing GRB2 like endophilin B1	gene	biological_process-&-1&-GO:0032801-&&-receptor catabolic process-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:1903778-&&-protein localization to vacuolar membrane-%%-GO:0006915-&&-apoptotic process-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0048102-&&-autophagic cell death-%%-GO:0090148-&&-membrane fission-%%-GO:0006914-&&-autophagy-%%-GO:1903527-&&-positive regulation of membrane tubulation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0051259-&&-protein oligomerization-%%-GO:2000786-&&-positive regulation of autophagosome assembly-%%-GO:0042149-&&-cellular response to glucose starvation|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0030496-&&-midbody-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:SH3GLB1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04140-&&-Autophagy - animal	SH3GLB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3GLB1	0.40155637	0.08385744	56	4	FALSE	SH3GLB1	SH3GLB1	115.7407407	0	55	0	0.75161494	FALSE	1	SH3GLB1	204480	0.03607241
790830	taxon:9606	2.63494564	1.31E-04	171037	1902	forkhead box P3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0002362-&&-CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment-%%-GO:0032792-&&-negative regulation of CREB transcription factor activity-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0050710-&&-negative regulation of cytokine secretion-%%-GO:0042110-&&-T cell activation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0048302-&&-regulation of isotype switching to IgG isotypes-%%-GO:0002851-&&-positive regulation of peripheral T cell tolerance induction-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000320-&&-negative regulation of T-helper 17 cell differentiation-%%-GO:0002725-&&-negative regulation of T cell cytokine production-%%-GO:0033092-&&-positive regulation of immature T cell proliferation in thymus-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0002669-&&-positive regulation of T cell anergy-%%-GO:0002456-&&-T cell mediated immunity-%%-GO:0032831-&&-positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation-%%-GO:0009615-&&-response to virus-%%-GO:0032714-&&-negative regulation of interleukin-5 production-%%-GO:0032914-&&-positive regulation of transforming growth factor beta1 production-%%-GO:0042036-&&-negative regulation of cytokine biosynthetic process-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0045077-&&-negative regulation of interferon-gamma biosynthetic process-%%-GO:0045085-&&-negative regulation of interleukin-2 biosynthetic process-%%-GO:0002513-&&-tolerance induction to self antigen-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0031064-&&-negative regulation of histone deacetylation-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0002677-&&-negative regulation of chronic inflammatory response-%%-GO:0032713-&&-negative regulation of interleukin-4 production-%%-GO:0048294-&&-negative regulation of isotype switching to IgE isotypes-%%-GO:0001816-&&-cytokine production-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0002667-&&-regulation of T cell anergy-%%-GO:0043029-&&-T cell homeostasis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:FOXP3			KEGG-&-1&-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)	FOXP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXP3	0.37951447	0.06883117	56	4	FALSE	FOXP3	FOXP3	98.48214286	0	56	0	0.72750906	FALSE	0	FOXP3	165896	0.04231467
791179	taxon:9606	2.57412951	1.97E-04	169807	1902	activating transcription factor 7 interacting protein	gene	biological_process-&-1&-GO:0045898-&&-regulation of RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0016887-&&-ATPase activity	G:9606:ATF7IP				ATF7IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF7IP	0.38848084	0.05454545	56	4	FALSE	ATF7IP	ATF7IP	100.1964286	0	56	0	0.73764508	FALSE	0	ATF7IP	223910	0.0373219
791597	taxon:9606	2.35229242	1.26E-04	167877	1902	RNA polymerase II associated protein 3	gene	cellular_component-&-1&-GO:0097255-&&-R2TP complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RPAP3				RPAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPAP3	0.42511721	0.17959469	56	4	FALSE	RPAP3	RPAP3	202.537037	0	55	0	0.77461793	FALSE	1	RPAP3	223748	0.04946715
791627	taxon:9606	2.4244525	6.12E-05	167751	1902	cleavage and polyadenylation specific factor 7	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0051262-&&-protein tetramerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CPSF7			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CPSF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPSF7	0.41246426	0.16493506	56	4	FALSE	CPSF7	CPSF7	237.7857143	0	56	0	0.76259125	FALSE	0	CPSF7	168930	0.0656043
792081	taxon:9606	2.34945644	1.26E-04	182649	1902	clathrin light chain A	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0071439-&&-clathrin complex-%%-GO:0030118-&&-clathrin coat-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030125-&&-clathrin vesicle coat|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0032050-&&-clathrin heavy chain binding-%%-GO:0005515-&&-protein binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005198-&&-structural molecule activity	G:9606:CLTA			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05016-&&-Huntington disease-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle	CLTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLTA	0.42563036	0.22857143	56	4	FALSE	CLTA	CLTA	243.0714286	0	56	0	0.77509059	FALSE	0	CLTA	262540	0.05944083
792082	taxon:9606	2.57097841	8.59E-05	182648	1902	clathrin light chain B	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030125-&&-clathrin vesicle coat-%%-GO:0060170-&&-ciliary membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030118-&&-clathrin coat-%%-GO:0030132-&&-clathrin coat of coated pit-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0032050-&&-clathrin heavy chain binding-%%-GO:0042277-&&-peptide binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:CLTB			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05016-&&-Huntington disease-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle	CLTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLTB	0.38895698	0.24545455	56	4	FALSE	CLTB	CLTB	117.0892857	0	56	0	0.73817026	FALSE	0	CLTB	123134	0.04333995
792270	taxon:9606	2.56782732	5.33E-05	182314	1902	septin 7	gene	biological_process-&-1&-GO:0016476-&&-regulation of embryonic cell shape-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0030154-&&-cell differentiation-%%-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0000910-&&-cytokinesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0031105-&&-septin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030496-&&-midbody-%%-GO:0005930-&&-axoneme-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0097227-&&-sperm annulus-%%-GO:0005634-&&-nucleus-%%-GO:0001725-&&-stress fiber-%%-GO:0005819-&&-spindle-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005525-&&-GTP binding	G:9606:SEPT7				SEPT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT7	0.38943429	0.20055905	56	4	FALSE	SEPT7	SEPT7	131.8703704	0	55	0	0.73869545	FALSE	1	SEPT7	99002	0.04813192
792417	taxon:9606	2.40554593	2.22E-04	182053	1902	casein kinase 1 delta	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1905426-&&-positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation-%%-GO:2000052-&&-positive regulation of non-canonical Wnt signaling pathway-%%-GO:0007030-&&-Golgi organization-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006364-&&-rRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006897-&&-endocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051225-&&-spindle assembly-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0061512-&&-protein localization to cilium-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0007020-&&-microtubule nucleation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005876-&&-spindle microtubule|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0050321-&&-tau-protein kinase activity	G:9606:CSNK1D			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04710-&&-Circadian rhythm	CSNK1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1D	0.41570605	0.12662338	56	4	FALSE	CSNK1D	CSNK1D	158.4464286	0	56	0	0.76574235	FALSE	0	CSNK1D	304032	0.04228144
792577	taxon:9606	2.47203403	1.20E-04	181784	1902	cyclin T1	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:1901409-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0016032-&&-viral process-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0003677-&&-DNA binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0008134-&&-transcription factor binding	G:9606:CCNT1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	CCNT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNT1	0.40452518	0.1453529	56	4	FALSE	CCNT1	CCNT1	159.6296296	0	55	0	0.75466099	FALSE	1	CCNT1	185574	0.0478483
792726	taxon:9606	2.52103356	1.33E-04	181494	1902	dihydrolipoamide dehydrogenase	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0048240-&&-sperm capacitation-%%-GO:0009106-&&-lipoate metabolic process-%%-GO:0006554-&&-lysine catabolic process-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0051068-&&-dihydrolipoamide metabolic process-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0007568-&&-aging-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate-%%-GO:0007369-&&-gastrulation-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045254-&&-pyruvate dehydrogenase complex-%%-GO:0031514-&&-motile cilium-%%-GO:0043159-&&-acrosomal matrix-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0045252-&&-oxoglutarate dehydrogenase complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0043544-&&-lipoamide binding-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0051287-&&-NAD binding-%%-GO:0004148-&&-dihydrolipoyl dehydrogenase activity	G:9606:DLD			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	DLD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLD	0.39666271	0.09573725	56	4	FALSE	DLD	DLD	132.962963	0	55	0	0.74649441	FALSE	1	DLD	180900	0.04400525
792831	taxon:9606	2.39593509	1.24E-04	181295	1902	stomatin	gene	biological_process-&-1&-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:1901585-&&-regulation of acid-sensing ion channel activity-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072562-&&-blood microparticle-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0031982-&&-vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005615-&&-extracellular space-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070063-&&-RNA polymerase binding	G:9606:STOM				STOM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STOM	0.41737358	0.11740042	56	4	FALSE	STOM	STOM	199.6296296	0	55	0	0.76734415	FALSE	1	STOM	248712	0.05256099
792859	taxon:9606	2.42980936	1.06E-04	181259	1902	enhancer of rudimentary homolog (Drosophila)	gene	biological_process-&-1&-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0006221-&&-pyrimidine nucleotide biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0006213-&&-pyrimidine nucleoside metabolic process-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0005515-&&-protein binding	G:9606:ERH				ERH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERH	0.41155492	0.16883117	56	4	FALSE	ERH	ERH	239	0	56	0	0.76169844	FALSE	0	ERH	248998	0.06658604
793048	taxon:9606	2.5389948	2.14E-04	180836	1902	glycogen synthase kinase 3 alpha	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0003073-&&-regulation of systemic arterial blood pressure-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:2000466-&&-negative regulation of glycogen (starch) synthase activity-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0010905-&&-negative regulation of UDP-glucose catabolic process-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:2000077-&&-negative regulation of type B pancreatic cell development-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:1904227-&&-negative regulation of glycogen synthase activity, transferring glucose-1-phosphate-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development-%%-GO:2000467-&&-positive regulation of glycogen (starch) synthase activity-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0045823-&&-positive regulation of heart contraction-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0071879-&&-positive regulation of adrenergic receptor signaling pathway-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0007399-&&-nervous system development-%%-GO:0036016-&&-cellular response to interleukin-3|cellular_component-&-1&-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0098794-&&-postsynapse|molecular_function-&-1&-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0005524-&&-ATP binding	G:9606:GSK3A			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04062-&&-Chemokine signaling pathway	GSK3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSK3A	0.39385666	0.06009783	56	4	FALSE	GSK3A	GSK3A	106.2037037	0	55	0	0.74350087	FALSE	1	GSK3A	225652	0.0363199
787345	taxon:9606	2.44903104	1.37E-04	179616	1902	stathmin 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0009615-&&-response to virus-%%-GO:0007420-&&-brain development-%%-GO:0007019-&&-microtubule depolymerization-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0007409-&&-axonogenesis-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005874-&&-microtubule-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0015631-&&-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:STMN1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway	STMN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STMN1	0.40832476	0.11515152	55	4	FALSE	STMN1	STMN1	168.4909091	0	55	0	0.75849483	FALSE	0	STMN1	217354	0.04865291
787355	taxon:9606	2.40176461	8.97E-05	163212	1902	PGAM family member 5, mitochondrial serine/threonine protein phosphatase	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0070266-&&-necroptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0009400-&&-signal transducer, downstream of receptor, with serine/threonine phosphatase activity	G:9606:PGAM5			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04217-&&-Necroptosis	PGAM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGAM5	0.41636054	0.11784512	55	4	FALSE	PGAM5	PGAM5	249.8363636	0	55	0	0.76637256	FALSE	0	PGAM5	228944	0.06634625
787363	taxon:9606	2.51520403	1.16E-04	179561	1902	tripartite motif containing 37	gene	biological_process-&-1&-GO:0036353-&&-histone H2A-K119 monoubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0070842-&&-aggresome assembly-%%-GO:0046600-&&-negative regulation of centriole replication-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0016235-&&-aggresome-%%-GO:0005777-&&-peroxisome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TRIM37			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	TRIM37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM37	0.39758206	0.08998549	55	4	FALSE	TRIM37	TRIM37	140.0943396	0	54	0	0.74746599	FALSE	1	TRIM37	179362	0.04562618
787508	taxon:9606	2.5323775	1.39E-04	179319	1902	MNAT1, CDK activating kinase assembly factor	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007512-&&-adult heart development-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0021591-&&-ventricular system development-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0061575-&&-cyclin-dependent protein serine/threonine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:MNAT1			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	MNAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MNAT1	0.39488583	0.11178451	55	4	FALSE	MNAT1	MNAT1	153.1090909	0	55	0	0.74460375	FALSE	0	MNAT1	208120	0.05150393
787561	taxon:9606	2.49172838	1.27E-04	179176	1902	NADH:ubiquinone oxidoreductase subunit A9	gene	biological_process-&-1&-GO:1901006-&&-ubiquinone-6 biosynthetic process-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006814-&&-sodium ion transport-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005739-&&-mitochondrion-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0050662-&&-coenzyme binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:NDUFA9			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA9	0.40132785	0.23097643	55	4	FALSE	NDUFA9	NDUFA9	147.8545455	0	55	0	0.7513786	FALSE	0	NDUFA9	228834	0.04617001
787724	taxon:9606	2.38459115	1.38E-04	178868	1902	DNA polymerase delta 1, catalytic subunit	gene	biological_process-&-1&-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006266-&&-DNA ligation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006260-&&-DNA replication-%%-GO:0000723-&&-telomere maintenance-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006298-&&-mismatch repair-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006287-&&-base-excision repair, gap-filling-%%-GO:0009411-&&-response to UV-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0045004-&&-DNA replication proofreading-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0043625-&&-delta DNA polymerase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000109-&&-nucleotide-excision repair complex-%%-GO:0016235-&&-aggresome-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008296-&&-3'-5'-exodeoxyribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding	G:9606:POLD1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03410-&&-Base excision repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03420-&&-Nucleotide excision repair	POLD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLD1	0.4193591	0.13333333	55	4	FALSE	POLD1	POLD1	231.7272727	0	55	0	0.76923481	FALSE	0	POLD1	254224	0.05966934
788012	taxon:9606	2.49015283	7.82E-05	178399	1902	prefoldin subunit 2	gene	biological_process-&-1&-GO:0051495-&&-positive regulation of cytoskeleton organization-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016272-&&-prefoldin complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0005515-&&-protein binding	G:9606:PFDN2				PFDN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFDN2	0.40158178	0.10449927	55	4	FALSE	PFDN2	PFDN2	147.9245283	0	54	0	0.7516412	FALSE	1	PFDN2	146662	0.04577705
788128	taxon:9606	2.57523239	2.94E-04	178199	1902	protein tyrosine phosphatase, receptor type K	gene	biological_process-&-1&-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0016477-&&-cell migration-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0034644-&&-cellular response to UV-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0031175-&&-neuron projection development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031256-&&-leading edge membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:PTPRK				PTPRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRK	0.38831447	0.04716981	55	4	FALSE	PTPRK	PTPRK	94.09433962	0	54	0	0.73746127	FALSE	1	PTPRK	262478	0.03520738
788226	taxon:9606	2.36993855	1.37E-04	178051	1902	replication factor C subunit 5	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006281-&&-DNA repair-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031390-&&-Ctf18 RFC-like complex|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005524-&&-ATP binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0005515-&&-protein binding	G:9606:RFC5			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC5	0.42195187	0.19259259	55	4	FALSE	RFC5	RFC5	256.6545455	0	55	0	0.77167691	FALSE	0	RFC5	249606	0.06466734
788310	taxon:9606	2.43579644	1.94E-04	177905	1902	S100 calcium binding protein A4	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0001837-&&-epithelial to mesenchymal transition|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:S100A4				S100A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A4	0.41054334	0.06023222	55	4	FALSE	S100A4	S100A4	138.4528302	0	54	0	0.76070059	FALSE	1	S100A4	224672	0.03886538
788570	taxon:9606	2.56861509	9.59E-05	177419	1902	TATA-box binding protein associated factor 4	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:TAF4			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors-%%-hsa05016-&&-Huntington disease	TAF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF4	0.38931485	0.21552975	55	4	FALSE	TAF4	TAF4	168.8867925	0	54	0	0.73856415	FALSE	1	TAF4	177688	0.06133275
788923	taxon:9606	2.46541673	1.21E-04	176585	1902	nuclear receptor subfamily 0 group B member 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0032403-&&-protein complex binding	G:9606:NR0B2			KEGG-&-1&-hsa04976-&&-Bile secretion	NR0B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR0B2	0.40561094	0.13265993	55	4	FALSE	NR0B2	NR0B2	165.7272727	0	55	0	0.75576388	FALSE	0	NR0B2	211598	0.04892874
788964	taxon:9606	2.33622184	2.07E-04	176517	1902	ubiquitin conjugating enzyme E2 M	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0045116-&&-protein neddylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0018169-&&-ribosomal S6-glutamic acid ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019788-&&-NEDD8 transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:UBE2M			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2M	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2M	0.42804154	0.16835994	55	4	FALSE	UBE2M	UBE2M	274.3584906	0	54	0	0.77729636	FALSE	1	UBE2M	299392	0.06573925
789046	taxon:9606	2.51630692	5.91E-05	176297	1902	histone cluster 1 H2A family member k	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2AK			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AK	0.3974078	0.19191919	55	4	FALSE	HIST1H2AK	HIST1H2AK	245.8363636	0	55	0	0.74728218	FALSE	0	HIST1H2AK	240674	0.08022438
789094	taxon:9606	2.51142272	1.14E-04	176201	1902	ZPR1 zinc finger	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0061564-&&-axon development-%%-GO:0007165-&&-signal transduction-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0045927-&&-positive regulation of growth-%%-GO:0071931-&&-positive regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:1990261-&&-pre-mRNA catabolic process-%%-GO:0008380-&&-RNA splicing-%%-GO:0008283-&&-cell proliferation-%%-GO:0001834-&&-trophectodermal cell proliferation-%%-GO:2000672-&&-negative regulation of motor neuron apoptotic process-%%-GO:0006397-&&-mRNA processing-%%-GO:0030576-&&-Cajal body organization-%%-GO:1902742-&&-apoptotic process involved in development-%%-GO:0031641-&&-regulation of myelination-%%-GO:0021510-&&-spinal cord development-%%-GO:0042023-&&-DNA endoreduplication|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030424-&&-axon-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0030426-&&-growth cone-%%-GO:0043204-&&-perikaryon-%%-GO:0032797-&&-SMN complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031369-&&-translation initiation factor binding	G:9606:ZPR1				ZPR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZPR1	0.39818068	0.14612795	55	4	FALSE	ZPR1	ZPR1	118.5090909	0	55	0	0.74809621	FALSE	0	ZPR1	172632	0.03827875
789120	taxon:9606	2.37056877	1.28E-04	176156	1902	far upstream element binding protein 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:FUBP3				FUBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUBP3	0.42183969	0.17575758	55	4	FALSE	FUBP3	FUBP3	259.5636364	0	55	0	0.77157187	FALSE	0	FUBP3	266036	0.06563664
789205	taxon:9606	2.37828896	7.13E-05	176011	1902	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein	gene	biological_process-&-1&-GO:0002098-&&-tRNA wobble uridine modification-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006955-&&-immune response-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0033588-&&-Elongator holoenzyme complex-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0008607-&&-phosphorylase kinase regulator activity	G:9606:IKBKAP				IKBKAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKBKAP	0.42047035	0.1371553	55	4	FALSE	IKBKAP	IKBKAP	213.5660377	0	54	0	0.77028517	FALSE	1	IKBKAP	162666	0.05457325
789297	taxon:9606	2.48668662	8.04E-05	175796	1902	mediator complex subunit 17	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED17			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED17	0.40214154	0.32929293	55	4	FALSE	MED17	MED17	143.9090909	0	55	0	0.7522189	FALSE	0	MED17	160732	0.04407072
789463	taxon:9606	2.5407279	8.75E-05	175415	1902	chromodomain helicase DNA binding protein 1 like	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006281-&&-DNA repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:CHD1L				CHD1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD1L	0.39358799	0.12727273	55	4	FALSE	CHD1L	CHD1L	156	0	55	0	0.74321202	FALSE	0	CHD1L	177804	0.05366266
789498	taxon:9606	2.58263747	1.07E-04	175333	1902	phosphodiesterase 4D interacting protein	gene	biological_process-&-1&-GO:0043623-&&-cellular protein complex assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030016-&&-myofibril|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:PDE4DIP				PDE4DIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE4DIP	0.38720107	0.05319865	55	4	FALSE	PDE4DIP	PDE4DIP	95.41818182	0	55	0	0.73622709	FALSE	0	PDE4DIP	177040	0.03614283
789552	taxon:9606	2.58263747	1.07E-04	142434	1902	phosphodiesterase 4D interacting protein-like	gene		G:9606:LOC100996724				LOC100996724	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100996724	0.38720107	0.05319865	55	4	FALSE	LOC100996724	LOC100996724	95.41818182	0	55	0	0.73622709	FALSE	0	LOC100996724	177040	0.03614283
789590	taxon:9606	2.36442414	7.56E-05	175114	1902	G3BP stress granule assembly factor 2	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:G3BP2				G3BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-G3BP2	0.42293596	0.1986532	55	4	FALSE	G3BP2	G3BP2	259.6181818	0	55	0	0.77259598	FALSE	0	G3BP2	165092	0.06472201
789655	taxon:9606	2.52670553	1.61E-04	174965	1902	protein inhibitor of activated STAT 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016925-&&-protein sumoylation-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0045838-&&-positive regulation of membrane potential-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009725-&&-response to hormone-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0016874-&&-ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PIAS3			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04120-&&-Ubiquitin mediated proteolysis	PIAS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIAS3	0.39577228	0.12121212	55	4	FALSE	PIAS3	PIAS3	136.2727273	0	55	0	0.74554908	FALSE	0	PIAS3	231630	0.04545151
789741	taxon:9606	2.43248779	6.84E-05	174786	1902	structural maintenance of chromosomes 4	gene	biological_process-&-1&-GO:0051383-&&-kinetochore organization-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0045132-&&-meiotic chromosome segregation-%%-GO:0010032-&&-meiotic chromosome condensation-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation|cellular_component-&-1&-GO:0000796-&&-condensin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:SMC4				SMC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMC4	0.41110176	0.15016835	55	4	FALSE	SMC4	SMC4	220.1454546	0	55	0	0.76125204	FALSE	0	SMC4	184814	0.06128771
789797	taxon:9606	2.36521191	6.49E-05	174646	1902	DDB1 and CUL4 associated factor 7	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DCAF7				DCAF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF7	0.4227951	0.15959596	55	4	FALSE	DCAF7	DCAF7	215.4545455	0	55	0	0.77246468	FALSE	0	DCAF7	161282	0.05396702
789845	taxon:9606	2.44981881	8.21E-05	174527	1902	POP1 homolog, ribonuclease P/MRP subunit	gene	biological_process-&-1&-GO:0016078-&&-tRNA catabolic process-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0001682-&&-tRNA 5'-leader removal-%%-GO:0008033-&&-tRNA processing|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0000172-&&-ribonuclease MRP complex-%%-GO:0005655-&&-nucleolar ribonuclease P complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0000171-&&-ribonuclease MRP activity-%%-GO:0005515-&&-protein binding-%%-GO:0004526-&&-ribonuclease P activity	G:9606:POP1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03013-&&-RNA transport	POP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POP1	0.40819345	0.16981132	55	4	FALSE	POP1	POP1	209.1132076	0	54	0	0.75836353	FALSE	1	POP1	164784	0.06000477
789869	taxon:9606	2.42933669	1.01E-04	174473	1902	kinesin family member 2C	gene	biological_process-&-1&-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051301-&&-cell division-%%-GO:0007019-&&-microtubule depolymerization-%%-GO:0030951-&&-establishment or maintenance of microtubule cytoskeleton polarity-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0008283-&&-cell proliferation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051983-&&-regulation of chromosome segregation|cellular_component-&-1&-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005813-&&-centrosome-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0019237-&&-centromeric DNA binding	G:9606:KIF2C				KIF2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF2C	0.411635	0.08490566	55	4	FALSE	KIF2C	KIF2C	175.0754717	0	54	0	0.76177722	FALSE	1	KIF2C	190894	0.0487255
790190	taxon:9606	2.39908618	5.23E-05	173680	1902	ribosomal RNA processing 1B	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0010923-&&-negative regulation of phosphatase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005829-&&-cytosol-%%-GO:0000792-&&-heterochromatin-%%-GO:0005730-&&-nucleolus-%%-GO:0030688-&&-preribosome, small subunit precursor-%%-GO:0000791-&&-euchromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:RRP1B				RRP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRP1B	0.41682538	0.26464646	55	4	FALSE	RRP1B	RRP1B	255.2545455	0	55	0	0.76681897	FALSE	0	RRP1B	128054	0.0671097
790393	taxon:9606	2.42760359	6.50E-05	173131	1902	karyopherin subunit alpha 6	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005643-&&-nuclear pore-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNA6				KPNA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA6	0.41192887	0.12188552	55	4	FALSE	KPNA6	KPNA6	173.2909091	0	55	0	0.76206607	FALSE	0	KPNA6	139840	0.0478736
790601	taxon:9606	2.70946904	1.26E-04	155512	1902	centrosomal protein 170 pseudogene 1	gene	molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP170P1				CEP170P1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP170P1	0.369076	0.03338171	55	4	FALSE	CEP170P1	CEP170P1	62.98113208	0	54	0	0.71508849	FALSE	1	CEP170P1	134108	0.0335138
790750	taxon:9606	2.58263747	1.07E-04	154951	1902	phosphodiesterase 4D interacting protein-like	gene		G:9606:LOC653513				LOC653513	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC653513	0.38720107	0.05319865	55	4	FALSE	LOC653513	LOC653513	95.41818182	0	55	0	0.73622709	FALSE	0	LOC653513	177040	0.03614283
791383	taxon:9606	2.67370411	1.71E-04	168859	1902	ras homolog family member U	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0002102-&&-podosome|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:RHOU				RHOU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOU	0.37401296	0.02626263	55	4	FALSE	RHOU	RHOU	67.87272727	0	55	0	0.72104931	FALSE	0	RHOU	161542	0.03298905
791522	taxon:9606	2.50370254	1.54E-04	168260	1902	leucine rich repeat kinase 1	gene	biological_process-&-1&-GO:0036035-&&-osteoclast development-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045453-&&-bone resorption-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1902533-&&-positive regulation of intracellular signal transduction-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0050732-&&-negative regulation of peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:LRRK1				LRRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRK1	0.39940847	0.09796807	55	4	FALSE	LRRK1	LRRK1	127.2075472	0	54	0	0.74938291	FALSE	1	LRRK1	186772	0.04069623
792045	taxon:9606	2.52733575	9.26E-05	182689	1902	B-Raf proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048680-&&-positive regulation of axon regeneration-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0090150-&&-establishment of protein localization to membrane-%%-GO:0043367-&&-CD4-positive, alpha-beta T cell differentiation-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0030878-&&-thyroid gland development-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0015758-&&-glucose transport-%%-GO:0043369-&&-CD4-positive or CD8-positive, alpha-beta T cell lineage commitment-%%-GO:0030154-&&-cell differentiation-%%-GO:0060324-&&-face development-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051591-&&-response to cAMP-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0048538-&&-thymus development-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0060323-&&-head morphogenesis-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0035690-&&-cellular response to drug-%%-GO:2000301-&&-negative regulation of synaptic vesicle exocytosis-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0045580-&&-regulation of T cell differentiation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0010764-&&-negative regulation of fibroblast migration-%%-GO:0008542-&&-visual learning|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0043005-&&-neuron projection-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0044297-&&-cell body-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031267-&&-small GTPase binding	G:9606:BRAF			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa04720-&&-Long-term potentiation-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	BRAF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRAF	0.39567359	0.212627	55	4	FALSE	BRAF	BRAF	152.1132076	0	54	0	0.74544404	FALSE	1	BRAF	158532	0.05080601
792278	taxon:9606	2.49677013	1.11E-04	182307	1902	cell division cycle 34	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0070848-&&-response to growth factor-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0090261-&&-positive regulation of inclusion body assembly-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:CDC34			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CDC34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC34	0.40051745	0.10595065	55	4	FALSE	CDC34	CDC34	157.0377359	0	54	0	0.75053831	FALSE	1	CDC34	178552	0.04934962
792683	taxon:9606	2.49960611	6.98E-05	165182	1902	zinc finger CCCH-type containing 18	gene	cellular_component-&-1&-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZC3H18				ZC3H18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZC3H18	0.40006303	0.18114478	55	4	FALSE	ZC3H18	ZC3H18	167.4545455	0	55	0	0.75006565	FALSE	0	ZC3H18	130988	0.05299145
792723	taxon:9606	2.55742871	2.58E-04	181493	1902	discs large MAGUK scaffold protein 1	gene	biological_process-&-1&-GO:0060022-&&-hard palate development-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0046037-&&-GMP metabolic process-%%-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0016032-&&-viral process-%%-GO:1903764-&&-regulation of potassium ion export across plasma membrane-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0048745-&&-smooth muscle tissue development-%%-GO:0007399-&&-nervous system development-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0002369-&&-T cell cytokine production-%%-GO:1903286-&&-regulation of potassium ion import-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0051660-&&-establishment of centrosome localization-%%-GO:0042110-&&-T cell activation-%%-GO:0097120-&&-receptor localization to synapse-%%-GO:0030432-&&-peristalsis-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0007015-&&-actin filament organization-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0031579-&&-membrane raft organization-%%-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1903760-&&-regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0031641-&&-regulation of myelination-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0048608-&&-reproductive structure development-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:1902305-&&-regulation of sodium ion transmembrane transport-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043622-&&-cortical microtubule organization-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0043113-&&-receptor clustering-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007093-&&-mitotic cell cycle checkpoint|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031253-&&-cell projection membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005605-&&-basal lamina-%%-GO:0001772-&&-immunological synapse-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0005634-&&-nucleus-%%-GO:0033268-&&-node of Ranvier-%%-GO:0043219-&&-lateral loop-%%-GO:0097025-&&-MPP7-DLG1-LIN7 complex-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0014704-&&-intercalated disc-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005911-&&-cell-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0097016-&&-L27 domain binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:DLG1			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04530-&&-Tight junction-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	DLG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLG1	0.39101774	0.05805515	55	4	FALSE	DLG1	DLG1	95.24528302	0	54	0	0.74042855	FALSE	1	DLG1	280150	0.0339744
792925	taxon:9606	2.71860722	1.32E-04	164748	1902	EvC ciliary complex subunit 2	gene	biological_process-&-1&-GO:0007224-&&-smoothened signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005929-&&-cilium-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0060170-&&-ciliary membrane	G:9606:EVC2			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway	EVC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EVC2	0.36783541	0.02424242	55	4	FALSE	EVC2	EVC2	60.23636364	0	55	0	0.71356546	FALSE	0	EVC2	144318	0.03321387
792953	taxon:9606	2.56073736	3.39E-04	181091	1902	fibroblast growth factor receptor 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0016477-&&-cell migration-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0001759-&&-organ induction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007037-&&-vacuolar phosphate transport-%%-GO:0090272-&&-negative regulation of fibroblast growth factor production-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0070640-&&-vitamin D3 metabolic process-%%-GO:0021847-&&-ventricular zone neuroblast division-%%-GO:0001501-&&-skeletal system development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030901-&&-midbrain development-%%-GO:0035607-&&-fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development-%%-GO:0048378-&&-regulation of lateral mesodermal cell fate specification-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060117-&&-auditory receptor cell development-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048469-&&-cell maturation-%%-GO:0060665-&&-regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001764-&&-neuron migration-%%-GO:2001239-&&-regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0000165-&&-MAPK cascade-%%-GO:2000830-&&-positive regulation of parathyroid hormone secretion-%%-GO:0001525-&&-angiogenesis-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0001657-&&-ureteric bud development-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043009-&&-chordate embryonic development-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0090080-&&-positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway-%%-GO:2000546-&&-positive regulation of endothelial cell chemotaxis to fibroblast growth factor-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:1903465-&&-positive regulation of mitotic cell cycle DNA replication-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0010518-&&-positive regulation of phospholipase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0043235-&&-receptor complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008201-&&-heparin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005007-&&-fibroblast growth factor-activated receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0090722-&&-receptor-receptor interaction-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:FGFR1	FGFR1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	FGFR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGFR1	0.39051252	0.09796807	55	4	FALSE	FGFR1	FGFR1	115.2830189	0	54	0	0.73987711	FALSE	1	FGFR1	333306	0.04151896
787151	taxon:9606	2.46651962	9.76E-05	179979	1902	lectin, mannose binding 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0032527-&&-protein exit from endoplasmic reticulum-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0007596-&&-blood coagulation-%%-GO:0007030-&&-Golgi organization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0010638-&&-positive regulation of organelle organization-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0007029-&&-endoplasmic reticulum organization|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0044220-&&-host cell perinuclear region of cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0030017-&&-sarcomere-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:LMAN1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	LMAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMAN1	0.40542958	0.13277428	54	4	FALSE	LMAN1	LMAN1	155.1111111	0	54	0	0.75558006	FALSE	0	LMAN1	166306	0.0462604
787882	taxon:9606	2.71624389	1.85E-05	178657	1902	proteasome subunit beta 8	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0052548-&&-regulation of endopeptidase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016032-&&-viral process-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005839-&&-proteasome core complex-%%-GO:0005829-&&-cytosol-%%-GO:0000502-&&-proteasome complex-%%-GO:1990111-&&-spermatoproteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMB8			KEGG-&-1&-hsa03050-&&-Proteasome	PSMB8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMB8	0.36815545	0.52564103	54	4	FALSE	PSMB8	PSMB8	107.4615385	0	53	0	0.71395935	FALSE	1	PSMB8	34886	0.05867958
788020	taxon:9606	2.35323775	1.14E-04	178391	1902	phosphofructokinase, liver type	gene	biological_process-&-1&-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0006096-&&-glycolytic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005945-&&-6-phosphofructokinase complex-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0070061-&&-fructose binding-%%-GO:0003872-&&-6-phosphofructokinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0070095-&&-fructose-6-phosphate binding-%%-GO:0046872-&&-metal ion binding	G:9606:PFKL			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00052-&&-Galactose metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa00030-&&-Pentose phosphate pathway-%%-hsa04066-&&-HIF-1 signaling pathway	PFKL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKL	0.42494644	0.12368024	54	4	FALSE	PFKL	PFKL	237.0576923	0	53	0	0.77446037	FALSE	1	PFKL	224390	0.05824527
788173	taxon:9606	2.5174098	3.04E-05	178130	1902	recombination activating 1	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0048538-&&-thymus development-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0006955-&&-immune response-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0006310-&&-DNA recombination-%%-GO:0030183-&&-B cell differentiation-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0002331-&&-pre-B cell allelic exclusion-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0042393-&&-histone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046872-&&-metal ion binding	G:9606:RAG1			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa05340-&&-Primary immunodeficiency	RAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAG1	0.3972337	0.26319759	54	4	FALSE	RAG1	RAG1	241.9230769	0	53	0	0.74709837	FALSE	1	RAG1	121108	0.07904098
788188	taxon:9606	2.35591618	1.23E-04	178110	1902	arginyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006420-&&-arginyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004814-&&-arginine-tRNA ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0034618-&&-arginine binding-%%-GO:0000049-&&-tRNA binding	G:9606:RARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	RARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARS	0.42446332	0.23759609	54	4	FALSE	RARS	RARS	256.7407407	0	54	0	0.77401397	FALSE	0	RARS	214094	0.06327427
788471	taxon:9606	2.41893808	9.92E-05	177577	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:SMARCD2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCD2	0.41340455	0.18658281	54	4	FALSE	SMARCD2	SMARCD2	184.6666667	0	54	0	0.76351032	FALSE	0	SMARCD2	222518	0.05014887
788627	taxon:9606	2.41358122	1.20E-04	177285	1902	transcription factor AP-2 alpha	gene	biological_process-&-1&-GO:0003409-&&-optic cup structural organization-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0021559-&&-trigeminal nerve development-%%-GO:0010842-&&-retina layer formation-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0003404-&&-optic vesicle morphogenesis-%%-GO:0021623-&&-oculomotor nerve formation-%%-GO:0071281-&&-cellular response to iron ion-%%-GO:0001822-&&-kidney development-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0070172-&&-positive regulation of tooth mineralization-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0060021-&&-palate development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:TFAP2A	TFAP2A	TRUE		TFAP2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAP2A	0.41432208	0.13556953	54	4	FALSE	TFAP2A	TFAP2A	181.0555556	0	54	0	0.76440313	FALSE	0	TFAP2A	199014	0.0490084
788829	taxon:9606	2.28391366	1.34E-04	176797	1902	ubiquitin C-terminal hydrolase L1	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0007628-&&-adult walking behavior-%%-GO:0048747-&&-muscle fiber development-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0007412-&&-axon target recognition-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0042755-&&-eating behavior-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0002931-&&-response to ischemia-%%-GO:0050905-&&-neuromuscular process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0044306-&&-neuron projection terminus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0031694-&&-alpha-2A adrenergic receptor binding-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008242-&&-omega peptidase activity	G:9606:UCHL1			KEGG-&-1&-hsa05012-&&-Parkinson disease	UCHL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UCHL1	0.43784492	0.1628232	54	4	FALSE	UCHL1	UCHL1	268.1666667	0	54	0	0.78601439	FALSE	0	UCHL1	267212	0.05947862
788940	taxon:9606	2.66188751	1.33E-04	176558	1902	TEA domain transcription factor 2	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0030903-&&-notochord development-%%-GO:0048568-&&-embryonic organ development-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0035329-&&-hippo signaling-%%-GO:0003143-&&-embryonic heart tube morphogenesis-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2000736-&&-regulation of stem cell differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0048368-&&-lateral mesoderm development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:TEAD2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	TEAD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEAD2	0.37567328	0.0349406	54	5	FALSE	TEAD2	TEAD2	79.81481481	0	54	0	0.72301875	FALSE	0	TEAD2	148786	0.03674595
789047	taxon:9606	2.51835513	5.78E-05	176298	1902	histone cluster 1 H2A family member i	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2AI			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AI	0.39708458	0.1977638	54	4	FALSE	HIST1H2AI	HIST1H2AI	248.8333333	0	54	0	0.74694081	FALSE	0	HIST1H2AI	236244	0.08152154
789126	taxon:9606	2.51835513	5.78E-05	176148	1902	histone cluster 1 H2A family member g	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2AG			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AG	0.39708458	0.1977638	54	4	FALSE	HIST1H2AG	HIST1H2AG	248.8333333	0	54	0	0.74694081	FALSE	0	HIST1H2AG	236244	0.08152154
789149	taxon:9606	2.70190641	7.46E-05	176102	1902	proline-serine-threonine phosphatase interacting protein 1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0045087-&&-innate immune response-%%-GO:0006897-&&-endocytosis-%%-GO:0006954-&&-inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0032154-&&-cleavage furrow-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0001931-&&-uropod-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PSTPIP1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	PSTPIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSTPIP1	0.37010904	0.0698812	54	4	FALSE	PSTPIP1	PSTPIP1	92.88888889	0	54	0	0.71634893	FALSE	0	PSTPIP1	102842	0.04874627
789174	taxon:9606	2.51835513	5.78E-05	176051	1902	histone cluster 1 H2A family member l	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2AL			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AL	0.39708458	0.1977638	54	4	FALSE	HIST1H2AL	HIST1H2AL	248.8333333	0	54	0	0.74694081	FALSE	0	HIST1H2AL	236244	0.08152154
789177	taxon:9606	2.51835513	5.78E-05	176047	1902	histone cluster 1 H2A family member m	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:HIST1H2AM			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AM	0.39708458	0.1977638	54	4	FALSE	HIST1H2AM	HIST1H2AM	248.8333333	0	54	0	0.74694081	FALSE	0	HIST1H2AM	236244	0.08152154
789409	taxon:9606	2.46793761	9.62E-05	175541	1902	general transcription factor IIIC subunit 4	gene	biological_process-&-1&-GO:0006384-&&-transcription initiation from RNA polymerase III promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0016573-&&-histone acetylation-%%-GO:0042797-&&-tRNA transcription from RNA polymerase III promoter-%%-GO:0042791-&&-5S class rRNA transcription from RNA polymerase III type 1 promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000127-&&-transcription factor TFIIIC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:GTF3C4				GTF3C4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF3C4	0.40519663	0.11111111	54	4	FALSE	GTF3C4	GTF3C4	166.6111111	0	54	0	0.75534373	FALSE	0	GTF3C4	183642	0.04940835
789418	taxon:9606	2.49487947	6.94E-05	175524	1902	thioredoxin like 1	gene	biological_process-&-1&-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0016671-&&-oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor-%%-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0047134-&&-protein-disulfide reductase activity-%%-GO:0004791-&&-thioredoxin-disulfide reductase activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:TXNL1				TXNL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNL1	0.40082097	0.2613557	54	4	FALSE	TXNL1	TXNL1	154.1666667	0	54	0	0.75085342	FALSE	0	TXNL1	107544	0.04818635
789835	taxon:9606	2.44714038	5.42E-05	174540	1902	SUB1 homolog, transcriptional regulator	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:SUB1				SUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUB1	0.40864023	0.10708899	54	4	FALSE	SUB1	SUB1	179.3076923	0	53	0	0.75880994	FALSE	1	SUB1	123140	0.05134814
789844	taxon:9606	2.45060659	1.65E-04	174531	1902	peroxiredoxin 3	gene	biological_process-&-1&-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0006915-&&-apoptotic process-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0018171-&&-peptidyl-cysteine oxidation-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0001893-&&-maternal placenta development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008785-&&-alkyl hydroperoxide reductase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:PRDX3				PRDX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX3	0.40806223	0.1040724	54	4	FALSE	PRDX3	PRDX3	228.0961539	0	53	0	0.75823224	FALSE	1	PRDX3	235784	0.06597779
789981	taxon:9606	2.55285962	1.67E-04	174196	1902	IKAROS family zinc finger 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030888-&&-regulation of B cell proliferation-%%-GO:0007498-&&-mesoderm development-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045619-&&-regulation of lymphocyte differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042113-&&-B cell activation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0046872-&&-metal ion binding	G:9606:IKZF3				IKZF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKZF3	0.39171758	0.07088989	54	4	FALSE	IKZF3	IKZF3	113.0769231	0	53	0	0.74119006	FALSE	1	IKZF3	207206	0.03989535
790129	taxon:9606	2.37513786	6.38E-05	173804	1902	DExH-box helicase 30	gene	biological_process-&-1&-GO:1902775-&&-mitochondrial large ribosomal subunit assembly-%%-GO:0006396-&&-RNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:DHX30				DHX30	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX30	0.42102819	0.23200559	54	4	FALSE	DHX30	DHX30	294.4814815	0	54	0	0.77081036	FALSE	0	DHX30	171400	0.07486981
790373	taxon:9606	2.59697495	1.83E-04	173190	1902	SNAP associated protein	gene	biological_process-&-1&-GO:0032438-&&-melanosome organization-%%-GO:0034629-&&-cellular protein complex localization-%%-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:1902824-&&-positive regulation of late endosome to lysosome transport-%%-GO:0097352-&&-autophagosome maturation-%%-GO:1902774-&&-late endosome to lysosome transport-%%-GO:0007042-&&-lysosomal lumen acidification-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0051604-&&-protein maturation-%%-GO:0032418-&&-lysosome localization-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0072553-&&-terminal button organization-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0031175-&&-neuron projection development-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0016032-&&-viral process-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0099078-&&-BORC complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030141-&&-secretory granule-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding	G:9606:SNAPIN				SNAPIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAPIN	0.3850634	0.03703704	54	4	FALSE	SNAPIN	SNAPIN	88.18518519	0	54	0	0.73383751	FALSE	0	SNAPIN	191908	0.03480748
790404	taxon:9606	2.69922798	1.60E-04	173104	1902	syntaxin 12	gene	biological_process-&-1&-GO:0048278-&&-vesicle docking-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0033344-&&-cholesterol efflux-%%-GO:0006906-&&-vesicle fusion-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0031982-&&-vesicle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0010008-&&-endosome membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0012505-&&-endomembrane system-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0031201-&&-SNARE complex|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding	G:9606:STX12			KEGG-&-1&-hsa04145-&&-Phagosome	STX12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX12	0.3704763	0.06568833	54	4	FALSE	STX12	STX12	63.35185185	0	54	0	0.71679534	FALSE	0	STX12	152362	0.03272372
790490	taxon:9606	2.38017961	3.95E-05	172714	1902	ribosomal L1 domain containing 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006412-&&-translation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0000470-&&-maturation of LSU-rRNA-%%-GO:2000772-&&-regulation of cellular senescence|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0030686-&&-90S preribosome-%%-GO:0016020-&&-membrane-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:RSL1D1				RSL1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RSL1D1	0.42013636	0.30957372	54	4	FALSE	RSL1D1	RSL1D1	292.962963	0	54	0	0.76997006	FALSE	0	RSL1D1	133028	0.0751525
790527	taxon:9606	2.47880889	5.66E-05	172593	1902	programmed cell death 4	gene	biological_process-&-1&-GO:0007569-&&-cell aging-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:1904761-&&-negative regulation of myofibroblast differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PDCD4			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer	PDCD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD4	0.40341956	0.09879336	54	4	FALSE	PDCD4	PDCD4	171.0192308	0	53	0	0.75353185	FALSE	1	PDCD4	130184	0.05191257
791029	taxon:9606	2.42082874	9.99E-05	170305	1902	NOP2/Sun RNA methyltransferase family member 2	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0030488-&&-tRNA methylation-%%-GO:0033313-&&-meiotic cell cycle checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0033391-&&-chromatoid body-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016428-&&-tRNA (cytosine-5-)-methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0000049-&&-tRNA binding	G:9606:NSUN2				NSUN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSUN2	0.41308168	0.15863033	54	4	FALSE	NSUN2	NSUN2	222.5925926	0	54	0	0.76319521	FALSE	0	NSUN2	205312	0.06085741
791114	taxon:9606	2.71403813	1.06E-04	169997	1902	transmembrane protein 63B	gene	biological_process-&-1&-GO:0006811-&&-ion transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0000166-&&-nucleotide binding	G:9606:TMEM63B				TMEM63B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM63B	0.36845466	0.07267645	54	4	FALSE	TMEM63B	TMEM63B	71.16666667	0	54	0	0.71432698	FALSE	0	TMEM63B	115436	0.038566
791422	taxon:9606	2.44335907	7.06E-05	168702	1902	mitochondrial ribosomal protein S9	gene	biological_process-&-1&-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:MRPS9			KEGG-&-1&-hsa03010-&&-Ribosome	MRPS9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS9	0.40927263	0.25296995	54	4	FALSE	MRPS9	MRPS9	193.3518519	0	54	0	0.75944016	FALSE	0	MRPS9	140548	0.05490338
791590	taxon:9606	2.70348196	1.05E-04	167908	1902	centrosomal protein 63	gene	biological_process-&-1&-GO:0098535-&&-de novo centriole assembly involved in multi-ciliated epithelial cell differentiation-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005814-&&-centriole-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP63				CEP63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP63	0.36989335	0.12928022	54	4	FALSE	CEP63	CEP63	76	0	54	0	0.71608634	FALSE	0	CEP63	124224	0.03915835
791657	taxon:9606	2.58799433	1.37E-04	167560	1902	TSC22 domain family member 4	gene	biological_process-&-1&-GO:0070236-&&-negative regulation of activation-induced cell death of T cells-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TSC22D4				TSC22D4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC22D4	0.38639961	0.04821803	54	4	FALSE	TSC22D4	TSC22D4	90.92592593	0	54	0	0.73533428	FALSE	0	TSC22D4	167148	0.03502789
791728	taxon:9606	2.36710257	1.18E-04	167160	1902	epiplakin 1	gene	biological_process-&-1&-GO:1905041-&&-regulation of epithelium regeneration-%%-GO:0051548-&&-negative regulation of keratinocyte migration-%%-GO:0008150-&&-biological_process-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0097356-&&-perinucleolar compartment-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0045095-&&-keratin filament-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0019215-&&-intermediate filament binding-%%-GO:0003723-&&-RNA binding	G:9606:EPPK1				EPPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPPK1	0.4224574	0.11740042	54	4	FALSE	EPPK1	EPPK1	245.9444444	0	54	0	0.77214957	FALSE	0	EPPK1	248116	0.06157071
792017	taxon:9606	2.53867969	1.09E-04	182724	1902	BH3 interacting domain death agonist	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0090150-&&-establishment of protein localization to membrane-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0007420-&&-brain development-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032355-&&-response to estradiol-%%-GO:0042775-&&-mitochondrial ATP synthesis coupled electron transport-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0010918-&&-positive regulation of mitochondrial membrane potential-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2000271-&&-positive regulation of fibroblast apoptotic process-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0097345-&&-mitochondrial outer membrane permeabilization-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032592-&&-integral component of mitochondrial membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005123-&&-death receptor binding	G:9606:BID			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05416-&&-Viral myocarditis-%%-hsa04210-&&-Apoptosis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04217-&&-Necroptosis	BID	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BID	0.39390554	0.13122172	54	4	FALSE	BID	BID	126.5769231	0	53	0	0.74355338	FALSE	1	BID	164172	0.0433285
792353	taxon:9606	2.40775169	9.17E-05	182172	1902	cold inducible RNA binding protein	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0034063-&&-stress granule assembly-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0009411-&&-response to UV|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030371-&&-translation repressor activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0070181-&&-small ribosomal subunit rRNA binding	G:9606:CIRBP				CIRBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIRBP	0.41532522	0.15932914	54	4	FALSE	CIRBP	CIRBP	226.3148148	0	54	0	0.76537472	FALSE	0	CIRBP	174716	0.06065435
792544	taxon:9606	2.53080195	2.72E-04	181828	1902	caspase 9	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0034349-&&-glial cell apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006508-&&-proteolysis-%%-GO:0030220-&&-platelet formation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0034644-&&-cellular response to UV-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0042770-&&-signal transduction in response to DNA damage-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043293-&&-apoptosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP9	CASP9	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05012-&&-Parkinson disease-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05416-&&-Viral myocarditis-%%-hsa04210-&&-Apoptosis-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance	CASP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP9	0.39513167	0.12518854	54	4	FALSE	CASP9	CASP9	119.4615385	0	53	0	0.74486634	FALSE	1	CASP9	311644	0.04039438
792804	taxon:9606	2.40239483	1.44E-04	181346	1902	eukaryotic translation initiation factor 5	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0001731-&&-formation of translation preinitiation complex|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0071074-&&-eukaryotic initiation factor eIF2 binding	G:9606:EIF5			KEGG-&-1&-hsa03013-&&-RNA transport	EIF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF5	0.41625131	0.17330538	54	4	FALSE	EIF5	EIF5	181.2777778	0	54	0	0.76626753	FALSE	0	EIF5	200220	0.04811767
792913	taxon:9606	2.45864188	1.08E-04	181167	1902	glucose-6-phosphate dehydrogenase	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0051156-&&-glucose 6-phosphate metabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0006740-&&-NADPH regeneration-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0046390-&&-ribose phosphate biosynthetic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0009051-&&-pentose-phosphate shunt, oxidative branch-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development-%%-GO:0010041-&&-response to iron(III) ion-%%-GO:0010734-&&-negative regulation of protein glutathionylation-%%-GO:0019322-&&-pentose biosynthetic process-%%-GO:0032094-&&-response to food-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006739-&&-NADP metabolic process-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:1904879-&&-positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0021762-&&-substantia nigra development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005536-&&-glucose binding-%%-GO:0004345-&&-glucose-6-phosphate dehydrogenase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0050661-&&-NADP binding-%%-GO:0042802-&&-identical protein binding	G:9606:G6PD			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00030-&&-Pentose phosphate pathway	G6PD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-G6PD	0.40672861	0.17722474	54	4	FALSE	G6PD	G6PD	174.1923077	0	53	0	0.75689302	FALSE	1	G6PD	175286	0.05084222
792936	taxon:9606	2.44477706	1.22E-04	181118	1902	Fanconi anemia complementation group D2	gene	biological_process-&-1&-GO:0048854-&&-brain morphogenesis-%%-GO:0006281-&&-DNA repair-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0045589-&&-regulation of regulatory T cell differentiation-%%-GO:2000348-&&-regulation of CD40 signaling pathway-%%-GO:0007129-&&-synapsis-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007276-&&-gamete generation-%%-GO:0050727-&&-regulation of inflammatory response|cellular_component-&-1&-GO:0000793-&&-condensed chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0070182-&&-DNA polymerase binding	G:9606:FANCD2			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCD2	0.40903525	0.14116003	54	4	FALSE	FANCD2	FANCD2	164.4814815	0	54	0	0.75920382	FALSE	0	FANCD2	199134	0.0470004
793061	taxon:9606	2.41027257	8.80E-04	180819	1902	glutathione S-transferase pi 1	gene	biological_process-&-1&-GO:0035726-&&-common myeloid progenitor cell proliferation-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0071672-&&-negative regulation of smooth muscle cell chemotaxis-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0043651-&&-linoleic acid metabolic process-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0007417-&&-central nervous system development-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0071460-&&-cellular response to cell-matrix adhesion-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0043200-&&-response to amino acid-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0070664-&&-negative regulation of leukocyte proliferation-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0035732-&&-nitric oxide storage-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0009890-&&-negative regulation of biosynthetic process-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0033591-&&-response to L-ascorbic acid-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0051771-&&-negative regulation of nitric-oxide synthase biosynthetic process|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0097057-&&-TRAF2-GSTP1 complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0035730-&&-S-nitrosoglutathione binding-%%-GO:0043295-&&-glutathione binding-%%-GO:0005515-&&-protein binding-%%-GO:0035731-&&-dinitrosyl-iron complex binding-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0070026-&&-nitric oxide binding-%%-GO:0004364-&&-glutathione transferase activity-%%-GO:0019207-&&-kinase regulator activity-%%-GO:0008432-&&-JUN kinase binding	G:9606:GSTP1	GSTP1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTP1	0.41489084	0.08823529	54	4	FALSE	GSTP1	GSTP1	228.7307692	0	53	0	0.76495457	FALSE	1	GSTP1	1222354	0.06165052
793162	taxon:9606	2.75374193	2.11E-04	180612	1902	G protein subunit alpha q	gene	biological_process-&-1&-GO:0016322-&&-neuron remodeling-%%-GO:0048066-&&-developmental pigmentation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007507-&&-heart development-%%-GO:0009649-&&-entrainment of circadian clock-%%-GO:0042711-&&-maternal behavior-%%-GO:0007596-&&-blood coagulation-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0001501-&&-skeletal system development-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0009791-&&-post-embryonic development-%%-GO:0001508-&&-action potential-%%-GO:0007603-&&-phototransduction, visible light-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0035412-&&-regulation of catenin import into nucleus-%%-GO:0045634-&&-regulation of melanocyte differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0021884-&&-forebrain neuron development-%%-GO:0050821-&&-protein stabilization-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body-%%-GO:0001750-&&-photoreceptor outer segment|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0031826-&&-type 2A serotonin receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:GNAQ	GNAQ	TRUE	KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05146-&&-Amoebiasis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04924-&&-Renin secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04540-&&-Gap junction-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04713-&&-Circadian entrainment-%%-hsa05016-&&-Huntington disease-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNAQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAQ	0.36314224	0.02865762	54	4	FALSE	GNAQ	GNAQ	50.53846154	0	53	0	0.70770968	FALSE	1	GNAQ	184240	0.03138981
787188	taxon:9606	2.49834568	1.10E-04	179907	1902	SMAD family member 5	gene	biological_process-&-1&-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060348-&&-bone development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0002051-&&-osteoblast fate commitment-%%-GO:0007281-&&-germ cell development-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007165-&&-signal transduction-%%-GO:0051216-&&-cartilage development-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0001880-&&-Mullerian duct regression|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0071141-&&-SMAD protein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0030618-&&-transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SMAD5	SMAD5	TRUE	KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	SMAD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD5	0.40026487	0.14296081	53	4	FALSE	SMAD5	SMAD5	144.5471698	0	53	0	0.75027572	FALSE	0	SMAD5	156180	0.04550884
787322	taxon:9606	2.38522136	1.20E-04	179665	1902	keratin 8	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0031424-&&-keratinization-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0051707-&&-response to other organism-%%-GO:0051599-&&-response to hydrostatic pressure-%%-GO:0045214-&&-sarcomere organization-%%-GO:0070268-&&-cornification-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005882-&&-intermediate filament-%%-GO:0043034-&&-costamere-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0045095-&&-keratin filament-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:KRT8				KRT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT8	0.4192483	0.09506531	53	4	FALSE	KRT8	KRT8	189.5660377	0	53	0	0.76912977	FALSE	0	KRT8	227112	0.048962
787663	taxon:9606	2.49598235	7.47E-05	178998	1902	nucleoporin 98	gene	biological_process-&-1&-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0006260-&&-DNA replication-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0000973-&&-posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery-%%-GO:0006999-&&-nuclear pore organization-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0016925-&&-protein sumoylation-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0034398-&&-telomere tethering at nuclear periphery|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0044614-&&-nuclear pore cytoplasmic filaments-%%-GO:0044615-&&-nuclear pore nuclear basket-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005643-&&-nuclear pore-%%-GO:0031080-&&-nuclear pore outer ring-%%-GO:0034399-&&-nuclear periphery-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0003723-&&-RNA binding	G:9606:NUP98			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A	NUP98	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP98	0.40064386	0.14039216	53	4	FALSE	NUP98	NUP98	168.3921569	0	52	0	0.75066961	FALSE	1	NUP98	141486	0.05272563
787701	taxon:9606	2.53978257	6.14E-04	178922	1902	plasminogen	gene	biological_process-&-1&-GO:0007596-&&-blood coagulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051919-&&-positive regulation of fibrinolysis-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0006508-&&-proteolysis-%%-GO:0048771-&&-tissue remodeling-%%-GO:0002576-&&-platelet degranulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0042730-&&-fibrinolysis-%%-GO:2000048-&&-negative regulation of cell-cell adhesion mediated by cadherin|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0005102-&&-receptor binding	G:9606:PLG			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	PLG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLG	0.39373449	0.06509804	53	4	FALSE	PLG	PLG	114.4313726	0	52	0	0.74336957	FALSE	1	PLG	580400	0.03945926
787777	taxon:9606	2.54293367	1.31E-04	178802	1902	protein phosphatase 2 regulatory subunit B'delta	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000159-&&-protein phosphatase type 2A complex|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2R5D			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R5D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R5D	0.39324659	0.11828737	53	4	FALSE	PPP2R5D	PPP2R5D	113.1509434	0	53	0	0.74284439	FALSE	0	PPP2R5D	165146	0.03887739
787936	taxon:9606	2.54120057	1.13E-04	178551	1902	3-oxoacid CoA-transferase 1	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0042182-&&-ketone catabolic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0007507-&&-heart development-%%-GO:0042594-&&-response to starvation-%%-GO:0046952-&&-ketone body catabolic process-%%-GO:0007584-&&-response to nutrient-%%-GO:0007420-&&-brain development-%%-GO:0042493-&&-response to drug-%%-GO:0009725-&&-response to hormone-%%-GO:0046950-&&-cellular ketone body metabolic process-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0060612-&&-adipose tissue development|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008260-&&-3-oxoacid CoA-transferase activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:OXCT1			KEGG-&-1&-hsa00072-&&-Synthesis and degradation of ketone bodies-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00650-&&-Butanoate metabolism	OXCT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OXCT1	0.39351479	0.09490196	53	4	FALSE	OXCT1	OXCT1	109.5686275	0	52	0	0.74313324	FALSE	1	OXCT1	146976	0.03756153
787942	taxon:9606	2.53600126	1.72E-04	178535	1902	phosphatidylethanolamine binding protein 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:PEBP1				PEBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEBP1	0.39432157	0.09490196	53	4	FALSE	PEBP1	PEBP1	133.4117647	0	52	0	0.74399979	FALSE	1	PEBP1	226972	0.04563976
788224	taxon:9606	2.47991177	4.76E-05	178054	1902	replication factor C subunit 2	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031390-&&-Ctf18 RFC-like complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:RFC2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC2	0.40324015	0.21190131	53	4	FALSE	RFC2	RFC2	206.7735849	0	53	0	0.75334804	FALSE	0	RFC2	119526	0.06282428
788377	taxon:9606	2.70946904	6.78E-05	177776	1902	signal sequence receptor subunit 3	gene	biological_process-&-1&-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005789-&&-endoplasmic reticulum membrane	G:9606:SSR3			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SSR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSR3	0.369076	0.08780842	53	4	FALSE	SSR3	SSR3	86.33962264	0	53	0	0.71508849	FALSE	0	SSR3	94384	0.04613955
788500	taxon:9606	2.50165432	3.43E-05	177546	1902	small nuclear ribonucleoprotein polypeptide E	gene	biological_process-&-1&-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0042633-&&-hair cycle|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0034715-&&-pICln-Sm protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005683-&&-U7 snRNP-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus-%%-GO:0005685-&&-U1 snRNP-%%-GO:0005829-&&-cytosol-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005689-&&-U12-type spliceosomal complex-%%-GO:0034709-&&-methylosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:SNRPE			KEGG-&-1&-hsa03040-&&-Spliceosome	SNRPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPE	0.39973548	0.30745098	53	4	FALSE	SNRPE	SNRPE	227.7647059	0	52	0	0.74972428	FALSE	1	SNRPE	93716	0.07204843
788508	taxon:9606	2.56483378	1.07E-04	177534	1902	superoxide dismutase 2	gene	biological_process-&-1&-GO:0008217-&&-regulation of blood pressure-%%-GO:0032364-&&-oxygen homeostasis-%%-GO:0000303-&&-response to superoxide-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0003069-&&-vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0001315-&&-age-dependent response to reactive oxygen species-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0004784-&&-superoxide dismutase activity-%%-GO:0042802-&&-identical protein binding	G:9606:SOD2	SOD2	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway	SOD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOD2	0.38988881	0.08235294	53	4	FALSE	SOD2	SOD2	115.4901961	0	52	0	0.73919437	FALSE	1	SOD2	143984	0.0418856
788995	taxon:9606	2.47565779	8.62E-05	176432	1902	FMR1 autosomal homolog 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007517-&&-muscle organ development-%%-GO:0017148-&&-negative regulation of translation-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043197-&&-dendritic spine-%%-GO:0005844-&&-polysome-%%-GO:0030424-&&-axon-%%-GO:0005737-&&-cytoplasm-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0043034-&&-costamere-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0033592-&&-RNA strand annealing activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:FXR1			KEGG-&-1&-hsa03013-&&-RNA transport	FXR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FXR1	0.40393305	0.10666667	53	4	FALSE	FXR1	FXR1	198.2745098	0	52	0	0.75405703	FALSE	1	FXR1	180524	0.05971587
789237	taxon:9606	2.42051363	1.61E-04	175928	1902	USO1 vesicle transport factor	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007030-&&-Golgi organization-%%-GO:0048211-&&-Golgi vesicle docking-%%-GO:0061025-&&-membrane fusion-%%-GO:0045056-&&-transcytosis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048280-&&-vesicle fusion with Golgi apparatus|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0001650-&&-fibrillar center-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005795-&&-Golgi stack|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003723-&&-RNA binding	G:9606:USO1				USO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USO1	0.41313546	0.07921569	53	4	FALSE	USO1	USO1	157.4705882	0	52	0	0.76324773	FALSE	1	USO1	225208	0.04296173
789447	taxon:9606	2.48889239	1.30E-04	175447	1902	aminopeptidase puromycin sensitive	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043171-&&-peptide catabolic process-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042277-&&-peptide binding-%%-GO:0004177-&&-aminopeptidase activity	G:9606:NPEPPS	NPEPPS	TRUE		NPEPPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPEPPS	0.40178515	0.11320755	53	4	FALSE	NPEPPS	NPEPPS	181.4150943	0	53	0	0.75185127	FALSE	0	NPEPPS	225292	0.05615384
789572	taxon:9606	2.52828108	9.22E-05	175155	1902	mediator complex subunit 24	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED24			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED24	0.39552564	0.32293179	53	4	FALSE	MED24	MED24	125.6981132	0	53	0	0.74528649	FALSE	0	MED24	147634	0.0420051
789658	taxon:9606	2.49740035	9.50E-05	174963	1902	NDC80, kinetochore complex component	gene	biological_process-&-1&-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0007059-&&-chromosome segregation-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore|cellular_component-&-1&-GO:0031262-&&-Ndc80 complex-%%-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0016020-&&-membrane-%%-GO:0000942-&&-condensed nuclear chromosome outer kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:NDC80				NDC80	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDC80	0.40041638	0.12784314	53	4	FALSE	NDC80	NDC80	139.9215686	0	52	0	0.75043328	FALSE	1	NDC80	153112	0.04385172
790008	taxon:9606	2.66425083	8.60E-05	174121	1902	centrosomal protein 164	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0006281-&&-DNA repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0097539-&&-ciliary transition fiber|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CEP164				CEP164	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP164	0.37534004	0.03846154	53	4	FALSE	CEP164	CEP164	78.28301887	0	53	0	0.72262486	FALSE	0	CEP164	106004	0.03616134
790108	taxon:9606	2.44477706	2.76E-05	173866	1902	ribosomal RNA processing 12 homolog	gene	cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:RRP12				RRP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRP12	0.40903525	0.26487663	53	4	FALSE	RRP12	RRP12	268.4528302	0	53	0	0.75920382	FALSE	0	RRP12	95828	0.07648229
790325	taxon:9606	2.45360013	8.89E-05	173315	1902	negative elongation factor complex member B	gene	biological_process-&-1&-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0050434-&&-positive regulation of viral transcription|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032021-&&-NELF complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NELFB				NELFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NELFB	0.40756437	0.18352941	53	4	FALSE	NELFB	NELFB	178.6078431	0	52	0	0.75773331	FALSE	1	NELFB	144202	0.05166709
790422	taxon:9606	2.46667717	1.89E-04	173036	1902	mitochondrial carrier 2	gene	biological_process-&-1&-GO:0090152-&&-establishment of protein localization to mitochondrial membrane involved in mitochondrial fission-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:1902108-&&-regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0071478-&&-cellular response to radiation-%%-GO:0035701-&&-hematopoietic stem cell migration-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0061484-&&-hematopoietic stem cell homeostasis-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0006089-&&-lactate metabolic process-%%-GO:0042775-&&-mitochondrial ATP synthesis coupled electron transport-%%-GO:0045820-&&-negative regulation of glycolytic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion	G:9606:MTCH2				MTCH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTCH2	0.40540368	0.23730044	53	4	FALSE	MTCH2	MTCH2	165.1509434	0	53	0	0.7555538	FALSE	0	MTCH2	282558	0.04902411
790814	taxon:9606	2.36962344	8.76E-05	171128	1902	stomatin like 2	gene	biological_process-&-1&-GO:1900210-&&-positive regulation of cardiolipin metabolic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0034982-&&-mitochondrial protein processing-%%-GO:0090297-&&-positive regulation of mitochondrial DNA replication-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:1990046-&&-stress-induced mitochondrial fusion-%%-GO:0010876-&&-lipid localization-%%-GO:0032623-&&-interleukin-2 production-%%-GO:0035710-&&-CD4-positive, alpha-beta T cell activation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0010918-&&-positive regulation of mitochondrial membrane potential-%%-GO:0006851-&&-mitochondrial calcium ion transport|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0001772-&&-immunological synapse-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0051020-&&-GTPase binding-%%-GO:1901612-&&-cardiolipin binding-%%-GO:0005515-&&-protein binding	G:9606:STOML2				STOML2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STOML2	0.42200798	0.16908563	53	4	FALSE	STOML2	STOML2	229.5283019	0	53	0	0.77172943	FALSE	0	STOML2	195214	0.05778658
790824	taxon:9606	2.36678746	4.85E-05	171072	1902	heterochromatin protein 1 binding protein 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070828-&&-heterochromatin organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0097298-&&-regulation of nucleus size-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005694-&&-chromosome-%%-GO:0000786-&&-nucleosome-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0005515-&&-protein binding	G:9606:HP1BP3				HP1BP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HP1BP3	0.42251365	0.26124819	53	4	FALSE	HP1BP3	HP1BP3	292.7924528	0	53	0	0.77220209	FALSE	0	HP1BP3	142064	0.07332171
790919	taxon:9606	2.58421301	6.73E-05	170702	1902	mediator complex subunit 15	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED15				MED15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED15	0.386965	0.28156749	53	4	FALSE	MED15	MED15	111.8113208	0	53	0	0.7359645	FALSE	0	MED15	116352	0.04246537
791095	taxon:9606	2.6535371	8.67E-05	170064	1902	ubiquitin conjugating enzyme E2 W	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006281-&&-DNA repair-%%-GO:0071218-&&-cellular response to misfolded protein|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE2W			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2W	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2W	0.37685548	0.03764706	53	4	FALSE	UBE2W	UBE2W	89.94117647	0	52	0	0.72441048	FALSE	1	UBE2W	143738	0.04020047
791130	taxon:9606	2.55018119	1.12E-04	169945	1902	DNA methyltransferase 1 associated protein 1	gene	biological_process-&-1&-GO:0043968-&&-histone H2A acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006281-&&-DNA repair-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0040008-&&-regulation of growth-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding	G:9606:DMAP1				DMAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMAP1	0.392129	0.19013062	53	4	FALSE	DMAP1	DMAP1	123.5283019	0	53	0	0.74163647	FALSE	0	DMAP1	151432	0.04317192
791173	taxon:9606	2.44414684	1.49E-04	169827	1902	coiled-coil domain containing 88A	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0010975-&&-regulation of neuron projection development-%%-GO:0006260-&&-DNA replication-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0016477-&&-cell migration-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0031929-&&-TOR signaling-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:1903566-&&-positive regulation of protein localization to cilium-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005814-&&-centriole-%%-GO:0030027-&&-lamellipodium-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003779-&&-actin binding-%%-GO:0051959-&&-dynein light intermediate chain binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CCDC88A				CCDC88A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC88A	0.40914072	0.06039216	53	4	FALSE	CCDC88A	CCDC88A	148.2156863	0	52	0	0.75930886	FALSE	1	CCDC88A	211442	0.04233881
791180	taxon:9606	2.43138491	1.12E-04	169801	1902	VPS35, retromer complex component	gene	biological_process-&-1&-GO:0007040-&&-lysosome organization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:2000331-&&-regulation of terminal button organization-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1905166-&&-negative regulation of lysosomal protein catabolic process-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:1903828-&&-negative regulation of cellular protein localization-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0061357-&&-positive regulation of Wnt protein secretion-%%-GO:0099639-&&-neurotransmitter receptor transport, endosome to plasma membrane-%%-GO:1902823-&&-negative regulation of late endosome to lysosome transport-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0099074-&&-mitochondrion to lysosome transport-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0090326-&&-positive regulation of locomotion involved in locomotory behavior-%%-GO:0045056-&&-transcytosis-%%-GO:0032268-&&-regulation of cellular protein metabolic process-%%-GO:0031648-&&-protein destabilization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903181-&&-positive regulation of dopamine biosynthetic process-%%-GO:1902950-&&-regulation of dendritic spine maintenance-%%-GO:0060161-&&-positive regulation of dopamine receptor signaling pathway-%%-GO:0031647-&&-regulation of protein stability|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0099073-&&-mitochondrion-derived vesicle-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030906-&&-retromer, cargo-selective complex-%%-GO:0005770-&&-late endosome-%%-GO:0097422-&&-tubular endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0005764-&&-lysosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0010008-&&-endosome membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030904-&&-retromer complex-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0008565-&&-protein transporter activity	G:9606:VPS35			KEGG-&-1&-hsa04144-&&-Endocytosis	VPS35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS35	0.41128823	0.11607843	53	4	FALSE	VPS35	VPS35	180.2352941	0	52	0	0.76143585	FALSE	1	VPS35	201648	0.05031457
791362	taxon:9606	2.49897589	7.89E-05	168971	1902	activation induced cytidine deaminase	gene	biological_process-&-1&-GO:0045190-&&-isotype switching-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0016445-&&-somatic diversification of immunoglobulins-%%-GO:0009972-&&-cytidine deamination-%%-GO:0030183-&&-B cell differentiation-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0006397-&&-mRNA processing-%%-GO:0080111-&&-DNA demethylation-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0090310-&&-negative regulation of methylation-dependent chromatin silencing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004126-&&-cytidine deaminase activity-%%-GO:0005515-&&-protein binding	G:9606:AICDA			KEGG-&-1&-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05340-&&-Primary immunodeficiency	AICDA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AICDA	0.40016392	0.08156863	53	4	FALSE	AICDA	AICDA	139	0	52	0	0.75017068	FALSE	1	AICDA	126034	0.04390694
791931	taxon:9606	2.5786986	4.00E-04	182856	1902	aldo-keto reductase family 1 member B	gene	biological_process-&-1&-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0035809-&&-regulation of urine volume-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0018931-&&-naphthalene metabolic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0097066-&&-response to thyroid hormone-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0072061-&&-inner medullary collecting duct development-%%-GO:0097238-&&-cellular response to methylglyoxal-%%-GO:0006950-&&-response to stress-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0046370-&&-fructose biosynthetic process-%%-GO:0006061-&&-sorbitol biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006700-&&-C21-steroid hormone biosynthetic process-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0044598-&&-doxorubicin metabolic process-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0042415-&&-norepinephrine metabolic process-%%-GO:0009414-&&-response to water deprivation-%%-GO:0031098-&&-stress-activated protein kinase signaling cascade-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade|cellular_component-&-1&-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0032838-&&-cell projection cytoplasm-%%-GO:0097454-&&-Schwann cell microvillus-%%-GO:0033010-&&-paranodal junction-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0043795-&&-glyceraldehyde oxidoreductase activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity	G:9606:AKR1B1	AKR1B1	TRUE	KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	AKR1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1B1	0.38779251	0.15965167	53	4	FALSE	AKR1B1	AKR1B1	112.3773585	0	53	0	0.73688357	FALSE	0	AKR1B1	486894	0.04198519
791945	taxon:9606	2.49188593	1.90E-04	182824	1902	bridging integrator 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0060988-&&-lipid tube assembly-%%-GO:0006997-&&-nucleus organization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0006897-&&-endocytosis-%%-GO:0008283-&&-cell proliferation-%%-GO:0051647-&&-nucleus localization-%%-GO:0016032-&&-viral process-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:0045664-&&-regulation of neuron differentiation|cellular_component-&-1&-GO:0030315-&&-T-tubule-%%-GO:0060987-&&-lipid tube-%%-GO:0031674-&&-I band-%%-GO:0030424-&&-axon-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043194-&&-axon initial segment-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0033268-&&-node of Ranvier-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0042802-&&-identical protein binding	G:9606:BIN1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	BIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIN1	0.40130248	0.07764706	53	4	FALSE	BIN1	BIN1	121.1960784	0	52	0	0.75135234	FALSE	1	BIN1	208210	0.03787781
791987	taxon:9606	2.57538995	6.24E-04	182771	1902	apolipoprotein A1	gene	biological_process-&-1&-GO:0033344-&&-cholesterol efflux-%%-GO:0030301-&&-cholesterol transport-%%-GO:0045723-&&-positive regulation of fatty acid biosynthetic process-%%-GO:0032489-&&-regulation of Cdc42 protein signal transduction-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0010873-&&-positive regulation of cholesterol esterification-%%-GO:0043627-&&-response to estrogen-%%-GO:0050821-&&-protein stabilization-%%-GO:0034380-&&-high-density lipoprotein particle assembly-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0050713-&&-negative regulation of interleukin-1 beta secretion-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:0019915-&&-lipid storage-%%-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0055085-&&-transmembrane transport-%%-GO:0031102-&&-neuron projection regeneration-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0060354-&&-negative regulation of cell adhesion molecule production-%%-GO:0030300-&&-regulation of intestinal cholesterol absorption-%%-GO:0010903-&&-negative regulation of very-low-density lipoprotein particle remodeling-%%-GO:0034375-&&-high-density lipoprotein particle remodeling-%%-GO:0034384-&&-high-density lipoprotein particle clearance-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0002576-&&-platelet degranulation-%%-GO:0060192-&&-negative regulation of lipase activity-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0051180-&&-vitamin transport-%%-GO:0030325-&&-adrenal gland development-%%-GO:0014012-&&-peripheral nervous system axon regeneration-%%-GO:0008211-&&-glucocorticoid metabolic process-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0018158-&&-protein oxidation-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0018206-&&-peptidyl-methionine modification-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0033700-&&-phospholipid efflux-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0055091-&&-phospholipid homeostasis-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0051345-&&-positive regulation of hydrolase activity-%%-GO:0070508-&&-cholesterol import-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0002740-&&-negative regulation of cytokine secretion involved in immune response-%%-GO:0051006-&&-positive regulation of lipoprotein lipase activity-%%-GO:0007584-&&-response to nutrient-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0010898-&&-positive regulation of triglyceride catabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0001932-&&-regulation of protein phosphorylation|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005634-&&-nucleus-%%-GO:0034364-&&-high-density lipoprotein particle-%%-GO:0034365-&&-discoidal high-density lipoprotein particle-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0034366-&&-spherical high-density lipoprotein particle-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0042627-&&-chylomicron-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0034361-&&-very-low-density lipoprotein particle|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005548-&&-phospholipid transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0060228-&&-phosphatidylcholine-sterol O-acyltransferase activator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0017127-&&-cholesterol transporter activity-%%-GO:0070653-&&-high-density lipoprotein particle receptor binding-%%-GO:0045499-&&-chemorepellent activity-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0034190-&&-apolipoprotein receptor binding-%%-GO:0055102-&&-lipase inhibitor activity-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0034191-&&-apolipoprotein A-I receptor binding-%%-GO:0008035-&&-high-density lipoprotein particle binding-%%-GO:0005543-&&-phospholipid binding	G:9606:APOA1	APOA1	TRUE	KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04977-&&-Vitamin digestion and absorption-%%-hsa03320-&&-PPAR signaling pathway	APOA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOA1	0.38829071	0.04078431	53	4	FALSE	APOA1	APOA1	86.11764706	0	52	0	0.73743501	FALSE	1	APOA1	587372	0.0322545
792098	taxon:9606	2.64849535	3.99E-04	182608	1902	collagen type I alpha 1 chain	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0071306-&&-cellular response to vitamin E-%%-GO:0060351-&&-cartilage development involved in endochondral bone morphogenesis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1902618-&&-cellular response to fluoride-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0001568-&&-blood vessel development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0015031-&&-protein transport-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0034505-&&-tooth mineralization-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0050776-&&-regulation of immune response-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0044691-&&-tooth eruption-%%-GO:0007601-&&-visual perception-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0032964-&&-collagen biosynthetic process-%%-GO:0042493-&&-response to drug-%%-GO:0031960-&&-response to corticosteroid-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0060346-&&-bone trabecula formation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0030168-&&-platelet activation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0001957-&&-intramembranous ossification-%%-GO:0007596-&&-blood coagulation-%%-GO:0060325-&&-face morphogenesis-%%-GO:0032355-&&-response to estradiol-%%-GO:0001958-&&-endochondral ossification-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0001501-&&-skeletal system development-%%-GO:0051591-&&-response to cAMP|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030141-&&-secretory granule-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005584-&&-collagen type I trimer-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL1A1	COL1A1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04611-&&-Platelet activation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection	COL1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL1A1	0.37757287	0.05568627	53	4	FALSE	COL1A1	COL1A1	71.54901961	0	52	0	0.72525077	FALSE	1	COL1A1	390596	0.03210321
792137	taxon:9606	2.47030093	2.31E-04	182534	1902	actin, alpha, cardiac muscle 1	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060047-&&-heart contraction-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0090131-&&-mesenchyme migration-%%-GO:0006915-&&-apoptotic process-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0045471-&&-response to ethanol-%%-GO:0033275-&&-actin-myosin filament sliding-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0042493-&&-response to drug-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031674-&&-I band-%%-GO:0005884-&&-actin filament-%%-GO:0072562-&&-blood microparticle-%%-GO:0030175-&&-filopodium-%%-GO:0005925-&&-focal adhesion-%%-GO:0042643-&&-actomyosin, actin portion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0044297-&&-cell body-%%-GO:0030017-&&-sarcomere-%%-GO:0030027-&&-lamellipodium-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017022-&&-myosin binding-%%-GO:0016887-&&-ATPase activity	G:9606:ACTC1			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	ACTC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTC1	0.40480898	0.08708273	53	4	FALSE	ACTC1	ACTC1	160.3207547	0	53	0	0.75494985	FALSE	0	ACTC1	275946	0.04788335
793001	taxon:9606	2.6800063	1.45E-04	181015	1902	FOS like 2, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003334-&&-keratinocyte development-%%-GO:0008219-&&-cell death|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:FOSL2	FOSL2	TRUE	KEGG-&-1&-hsa04380-&&-Osteoclast differentiation	FOSL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOSL2	0.37313345	0.08272859	53	4	FALSE	FOSL2	FOSL2	75.66037736	0	53	0	0.71999895	FALSE	0	FOSL2	147772	0.03669018
787268	taxon:9606	2.54293367	1.15E-04	179778	1902	JunB proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001570-&&-vasculogenesis-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0033687-&&-osteoblast proliferation-%%-GO:0010941-&&-regulation of cell death-%%-GO:0034097-&&-response to cytokine-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0051591-&&-response to cAMP-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060136-&&-embryonic process involved in female pregnancy-%%-GO:0046697-&&-decidualization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0009314-&&-response to radiation-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding	G:9606:JUNB			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation	JUNB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUNB	0.39324659	0.19673469	52	4	FALSE	JUNB	JUNB	133.86	0	51	0	0.74284439	FALSE	1	JUNB	160196	0.04615597
787568	taxon:9606	2.65274933	9.80E-05	179157	1902	NADH:ubiquinone oxidoreductase subunit S4	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0045333-&&-cellular respiration-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0007420-&&-brain development-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0051591-&&-response to cAMP-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0048146-&&-positive regulation of fibroblast proliferation|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFS4	NDUFS4	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS4	0.37696739	0.22699849	52	4	FALSE	NDUFS4	NDUFS4	96.59615385	0	52	0	0.72454178	FALSE	0	NDUFS4	124844	0.04359496
787621	taxon:9606	2.44761305	1.44E-04	179074	1902	N-myristoyltransferase 1	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0018008-&&-N-terminal peptidyl-glycine N-myristoylation-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway-%%-GO:0006499-&&-N-terminal protein myristoylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004379-&&-glycylpeptide N-tetradecanoyltransferase activity-%%-GO:0019107-&&-myristoyltransferase activity	G:9606:NMT1				NMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NMT1	0.40856131	0.18476621	52	4	FALSE	NMT1	NMT1	161.3846154	0	52	0	0.75873116	FALSE	0	NMT1	191246	0.04637619
787758	taxon:9606	2.60138648	1.87E-04	178829	1902	peroxisome proliferator activated receptor alpha	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:0007507-&&-heart development-%%-GO:0008544-&&-epidermis development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0072363-&&-regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032868-&&-response to insulin-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:1903038-&&-negative regulation of leukocyte cell-cell adhesion-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0072369-&&-regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0042060-&&-wound healing-%%-GO:0015908-&&-fatty acid transport-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0032099-&&-negative regulation of appetite-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0035095-&&-behavioral response to nicotine-%%-GO:0010891-&&-negative regulation of sequestering of triglyceride-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0010871-&&-negative regulation of receptor biosynthetic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0072366-&&-regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046321-&&-positive regulation of fatty acid oxidation-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0070166-&&-enamel mineralization-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0045776-&&-negative regulation of blood pressure|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0097371-&&-MDM2/MDM4 family protein binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008289-&&-lipid binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:PPARA	PPARA	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05160-&&-Hepatitis C-%%-hsa04931-&&-Insulin resistance-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway	PPARA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARA	0.38441039	0.08816327	52	4	FALSE	PPARA	PPARA	106.7	0	51	0	0.73310225	FALSE	1	PPARA	206272	0.04226984
787760	taxon:9606	2.55774382	1.48E-04	178828	1902	peroxisome proliferator activated receptor delta	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006915-&&-apoptotic process-%%-GO:0060612-&&-adipose tissue development-%%-GO:0008366-&&-axon ensheathment-%%-GO:0015758-&&-glucose transport-%%-GO:0015908-&&-fatty acid transport-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0043415-&&-positive regulation of skeletal muscle tissue regeneration-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0042060-&&-wound healing-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0014842-&&-regulation of skeletal muscle satellite cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0009299-&&-mRNA transcription-%%-GO:0033189-&&-response to vitamin A-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0045684-&&-positive regulation of epidermis development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0008654-&&-phospholipid biosynthetic process-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0009062-&&-fatty acid catabolic process-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0006029-&&-proteoglycan metabolic process-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0051546-&&-keratinocyte migration-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0046697-&&-decidualization-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007566-&&-embryo implantation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0006776-&&-vitamin A metabolic process-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0014823-&&-response to activity-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:2000288-&&-positive regulation of myoblast proliferation|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0070539-&&-linoleic acid binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008144-&&-drug binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008289-&&-lipid binding	G:9606:PPARD	PPARD	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer-%%-hsa03320-&&-PPAR signaling pathway	PPARD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARD	0.39096957	0.10204082	52	4	FALSE	PPARD	PPARD	127.34	0	51	0	0.74037603	FALSE	1	PPARD	190516	0.04546495
787904	taxon:9606	2.5738144	4.68E-05	178639	1902	proteasome 26S subunit, non-ATPase 9	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0070682-&&-proteasome regulatory particle assembly-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005838-&&-proteasome regulatory particle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0008540-&&-proteasome regulatory particle, base subcomplex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:PSMD9				PSMD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMD9	0.3885284	0.19909502	52	4	FALSE	PSMD9	PSMD9	133.0576923	0	52	0	0.7376976	FALSE	0	PSMD9	87544	0.04894397
787990	taxon:9606	2.47660312	1.96E-04	178441	1902	platelet derived growth factor receptor alpha	gene	biological_process-&-1&-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0001775-&&-cell activation-%%-GO:0070527-&&-platelet aggregation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0050920-&&-regulation of chemotaxis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0072277-&&-metanephric glomerular capillary formation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0016032-&&-viral process-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0001553-&&-luteinization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035790-&&-platelet-derived growth factor receptor-alpha signaling pathway-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:2000739-&&-regulation of mesenchymal stem cell differentiation-%%-GO:0038091-&&-positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0042060-&&-wound healing-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005018-&&-platelet-derived growth factor alpha-receptor activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:PDGFRA			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04540-&&-Gap junction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer	PDGFRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFRA	0.40377887	0.13714286	52	4	FALSE	PDGFRA	PDGFRA	147.94	0	51	0	0.75389948	FALSE	1	PDGFRA	230736	0.04488012
788025	taxon:9606	2.67417678	1.93E-05	178371	1902	bromodomain containing 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:BRD2				BRD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD2	0.37394686	0.29469388	52	4	FALSE	BRD2	BRD2	219.78	0	51	0	0.72097054	FALSE	1	BRD2	67142	0.10327068
788026	taxon:9606	2.52654798	5.10E-05	178370	1902	ring finger protein 4	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0090169-&&-regulation of spindle assembly-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0046685-&&-response to arsenic-containing substance-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0090234-&&-regulation of kinetochore assembly-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0085020-&&-protein K6-linked ubiquitination|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032184-&&-SUMO polymer binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031491-&&-nucleosome binding	G:9606:RNF4				RNF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF4	0.39579696	0.12734694	52	4	FALSE	RNF4	RNF4	158.98	0	51	0	0.74557534	FALSE	1	RNF4	108868	0.05274054
788488	taxon:9606	2.42917914	8.93E-05	177556	1902	fascin actin-bundling protein 1	gene	biological_process-&-1&-GO:0030035-&&-microspike assembly-%%-GO:0090091-&&-positive regulation of extracellular matrix disassembly-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0016477-&&-cell migration-%%-GO:0048870-&&-cell motility-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0032534-&&-regulation of microvillus assembly-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0035089-&&-establishment of apical/basal cell polarity|cellular_component-&-1&-GO:0005902-&&-microvillus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071437-&&-invadopodium-%%-GO:0031253-&&-cell projection membrane-%%-GO:0001725-&&-stress fiber-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0002102-&&-podosome-%%-GO:0030426-&&-growth cone-%%-GO:0031941-&&-filamentous actin-%%-GO:0044393-&&-microspike-%%-GO:0001726-&&-ruffle-%%-GO:0030175-&&-filopodium-%%-GO:0005911-&&-cell-cell junction-%%-GO:0043209-&&-myelin sheath-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008144-&&-drug binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:FSCN1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	FSCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FSCN1	0.41166169	0.12895928	52	4	FALSE	FSCN1	FSCN1	206.9038462	0	52	0	0.76180348	FALSE	0	FSCN1	172274	0.05751048
788592	taxon:9606	2.53442571	6.23E-05	177377	1902	transcription elongation factor A1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TCEA1				TCEA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEA1	0.3945667	0.14253394	52	4	FALSE	TCEA1	TCEA1	133.5384615	0	52	0	0.74426238	FALSE	0	TCEA1	121742	0.04512309
788773	taxon:9606	2.45643611	1.13E-04	176931	1902	death associated protein 3	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005763-&&-mitochondrial small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:DAP3				DAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAP3	0.40709384	0.19102041	52	4	FALSE	DAP3	DAP3	182.74	0	51	0	0.75726065	FALSE	1	DAP3	167908	0.05318579
789291	taxon:9606	2.56467622	5.17E-05	175818	1902	mediator complex subunit 21	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0001824-&&-blastocyst development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016592-&&-mediator complex|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:MED21				MED21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED21	0.38991277	0.29877551	52	4	FALSE	MED21	MED21	130.32	0	51	0	0.73922063	FALSE	1	MED21	93940	0.04660229
789312	taxon:9606	2.43737199	1.96E-04	175770	1902	eukaryotic translation initiation factor 4E family member 2	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005845-&&-mRNA cap binding complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0005515-&&-protein binding	G:9606:EIF4E2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04066-&&-HIF-1 signaling pathway	EIF4E2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4E2	0.41027796	0.08220211	52	4	FALSE	EIF4E2	EIF4E2	152.9038462	0	52	0	0.760438	FALSE	0	EIF4E2	310936	0.04310513
789446	taxon:9606	2.42949425	9.79E-05	175444	1902	trans-2,3-enoyl-CoA reductase	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0030497-&&-fatty acid elongation-%%-GO:0042761-&&-very long-chain fatty acid biosynthetic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0017099-&&-very-long-chain-acyl-CoA dehydrogenase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0005515-&&-protein binding	G:9606:TECR			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa01212-&&-Fatty acid metabolism	TECR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TECR	0.4116083	0.19532428	52	4	FALSE	TECR	TECR	194.7692308	0	52	0	0.76175096	FALSE	0	TECR	181028	0.05404684
789561	taxon:9606	2.53442571	6.23E-05	158792	1902	transcription elongation factor A1 pseudogene 2	gene		G:9606:TCEA1P2				TCEA1P2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEA1P2	0.3945667	0.14253394	52	4	FALSE	TCEA1P2	TCEA1P2	133.5384615	0	52	0	0.74426238	FALSE	0	TCEA1P2	121742	0.04512309
789748	taxon:9606	2.53804947	5.25E-05	174775	1902	actin related protein 2/3 complex subunit 3	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus|cellular_component-&-1&-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0030426-&&-growth cone-%%-GO:0016020-&&-membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:ARPC3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05131-&&-Shigellosis	ARPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARPC3	0.39400335	0.19381599	52	4	FALSE	ARPC3	ARPC3	158.8076923	0	52	0	0.74365842	FALSE	0	ARPC3	105736	0.05449158
789749	taxon:9606	2.40475815	1.47E-04	174774	1902	actin related protein 2/3 complex subunit 1B	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0032355-&&-response to estradiol-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0043627-&&-response to estrogen|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0036284-&&-tubulobulbar complex-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:ARPC1B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05131-&&-Shigellosis	ARPC1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARPC1B	0.41584223	0.18778281	52	4	FALSE	ARPC1B	ARPC1B	182.9230769	0	52	0	0.76587364	FALSE	0	ARPC1B	213934	0.04872751
790037	taxon:9606	2.61651174	7.80E-05	174044	1902	ubiquitin conjugating enzyme E2 C	gene	biological_process-&-1&-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0010458-&&-exit from mitosis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005680-&&-anaphase-promoting complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2C			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2C	0.38218823	0.14204082	52	4	FALSE	UBE2C	UBE2C	109.2	0	51	0	0.73058138	FALSE	1	UBE2C	107126	0.04482957
790195	taxon:9606	2.43296045	1.21E-04	173674	1902	ELKS/RAB6-interacting/CAST family member 1	gene	biological_process-&-1&-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0015031-&&-protein transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0045202-&&-synapse-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0008385-&&-IkappaB kinase complex|molecular_function-&-1&-GO:0043522-&&-leucine zipper domain binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0045296-&&-cadherin binding	G:9606:ERC1			KEGG-&-1&-hsa04064-&&-NF-kappa B signaling pathway	ERC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERC1	0.41102189	0.09469388	52	4	FALSE	ERC1	ERC1	175.28	0	51	0	0.76117326	FALSE	1	ERC1	199662	0.04891371
790280	taxon:9606	2.53757681	2.14E-04	173452	1902	integrin subunit beta 3 binding protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:ITGB3BP				ITGB3BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB3BP	0.39407674	0.03428571	52	5	FALSE	ITGB3BP	ITGB3BP	105.36	0	51	0	0.7437372	FALSE	1	ITGB3BP	220988	0.0360783
790309	taxon:9606	2.4857413	1.34E-04	173357	1902	breast cancer metastasis suppressor 1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:2000210-&&-positive regulation of anoikis-%%-GO:0090312-&&-positive regulation of protein deacetylation-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070822-&&-Sin3-type complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051059-&&-NF-kappaB binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:BRMS1				BRMS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRMS1	0.40229448	0.12326531	52	4	FALSE	BRMS1	BRMS1	157.02	0	51	0	0.75237645	FALSE	1	BRMS1	189176	0.04846368
790540	taxon:9606	2.45706633	1.08E-04	172546	1902	ubiquitin conjugating enzyme E2 S	gene	biological_process-&-1&-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051301-&&-cell division-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010458-&&-exit from mitosis-%%-GO:0035519-&&-protein K29-linked ubiquitination-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0044314-&&-protein K27-linked ubiquitination-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:UBE2S			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2S	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2S	0.40698942	0.10530612	52	4	FALSE	UBE2S	UBE2S	145.02	0	51	0	0.75715561	FALSE	1	UBE2S	161766	0.0421705
790693	taxon:9606	2.55522294	1.50E-04	171463	1902	protein kinase C and casein kinase substrate in neurons 3	gene	biological_process-&-1&-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0006897-&&-endocytosis-%%-GO:0097320-&&-plasma membrane tubulation-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0045806-&&-negative regulation of endocytosis|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:PACSIN3				PACSIN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PACSIN3	0.39135528	0.07183673	52	4	FALSE	PACSIN3	PACSIN3	131.54	0	51	0	0.74079618	FALSE	1	PACSIN3	200256	0.04677821
790854	taxon:9606	2.48132976	1.47E-04	170891	1902	ERBB receptor feedback inhibitor 1	gene	biological_process-&-1&-GO:0043589-&&-skin morphogenesis-%%-GO:0048286-&&-lung alveolus development-%%-GO:0042536-&&-negative regulation of tumor necrosis factor biosynthetic process-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0071474-&&-cellular hyperosmotic response-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0061469-&&-regulation of type B pancreatic cell proliferation-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0045616-&&-regulation of keratinocyte differentiation-%%-GO:0060428-&&-lung epithelium development-%%-GO:1903243-&&-negative regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0060426-&&-lung vasculature development-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0006950-&&-response to stress-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:ERRFI1				ERRFI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERRFI1	0.40300971	0.13959184	52	4	FALSE	ERRFI1	ERRFI1	169.84	0	51	0	0.75311171	FALSE	1	ERRFI1	202778	0.05189602
791188	taxon:9606	2.43500867	5.34E-05	169790	1902	cell division cycle and apoptosis regulator 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007049-&&-cell cycle-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding	G:9606:CCAR1				CCAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCAR1	0.41067616	0.16968326	52	4	FALSE	CCAR1	CCAR1	244.9423077	0	52	0	0.76083189	FALSE	0	CCAR1	159220	0.06837905
791337	taxon:9606	2.58893966	6.66E-05	169107	1902	coronin 1B	gene	biological_process-&-1&-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0016477-&&-cell migration-%%-GO:0071672-&&-negative regulation of smooth muscle cell chemotaxis-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0090135-&&-actin filament branching-%%-GO:0031529-&&-ruffle organization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0034316-&&-negative regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0042060-&&-wound healing-%%-GO:1902463-&&-protein localization to cell leading edge-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0071933-&&-Arp2/3 complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:CORO1B				CORO1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CORO1B	0.38625852	0.14285714	52	4	FALSE	CORO1B	CORO1B	119.86	0	51	0	0.73517672	FALSE	1	CORO1B	103482	0.0461
791649	taxon:9606	2.36206082	1.12E-04	167577	1902	factor interacting with PAPOLA and CPSF1	gene	biological_process-&-1&-GO:0006378-&&-mRNA polyadenylation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:FIP1L1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	FIP1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FIP1L1	0.42335912	0.15384615	52	4	FALSE	FIP1L1	FIP1L1	223.3461539	0	52	0	0.77298986	FALSE	0	FIP1L1	226496	0.05544307
791667	taxon:9606	2.62139594	1.66E-05	167531	1902	WD repeat domain 76	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus	G:9606:WDR76				WDR76	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR76	0.38147614	0.19457014	52	4	FALSE	WDR76	WDR76	202	0	52	0	0.72976734	FALSE	0	WDR76	60382	0.08361204
791681	taxon:9606	2.51520403	4.95E-05	167459	1902	WD repeat domain 61	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:2001162-&&-positive regulation of histone H3-K79 methylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0055087-&&-Ski complex-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0005634-&&-nucleus-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR61			KEGG-&-1&-hsa03018-&&-RNA degradation	WDR61	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR61	0.39758206	0.19230769	52	4	FALSE	WDR61	WDR61	200.4230769	0	52	0	0.74746599	FALSE	0	WDR61	131608	0.06514454
791747	taxon:9606	2.76933985	1.00E-04	167079	1902	keratin associated protein 4-12	gene	cellular_component-&-1&-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP4-12				KRTAP4-12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP4-12	0.36109689	0.16081633	52	5	FALSE	KRTAP4-12	KRTAP4-12	60.1	0	51	0	0.70511003	FALSE	1	KRTAP4-12	117208	0.03924084
791817	taxon:9606	2.69733732	4.82E-05	166723	1902	dpy-30, histone methyltransferase complex regulatory subunit	gene	biological_process-&-1&-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0016197-&&-endosomal transport-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)	G:9606:DPY30				DPY30	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPY30	0.37073598	0.09877551	52	4	FALSE	DPY30	DPY30	95.46	0	51	0	0.71711045	FALSE	1	DPY30	77808	0.04882744
792076	taxon:9606	2.53332283	7.03E-05	182659	1902	CDC like kinase 2	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0045721-&&-negative regulation of gluconeogenesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:CLK2				CLK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLK2	0.39473848	0.13959184	52	5	FALSE	CLK2	CLK2	139.94	0	51	0	0.7444462	FALSE	1	CLK2	110896	0.04715442
792497	taxon:9606	2.54466677	7.62E-05	181910	1902	formin like 1	gene	biological_process-&-1&-GO:0051014-&&-actin filament severing-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0006929-&&-substrate-dependent cell migration|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005829-&&-cytosol-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0032059-&&-bleb-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005522-&&-profilin binding-%%-GO:0003674-&&-molecular_function-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0032794-&&-GTPase activating protein binding	G:9606:FMNL1				FMNL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FMNL1	0.39297876	0.04816327	52	4	FALSE	FMNL1	FMNL1	127.42	0	51	0	0.74255554	FALSE	1	FMNL1	133566	0.04425339
792985	taxon:9606	2.46793761	4.86E-05	181043	1902	FLII, actin remodeling protein	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051014-&&-actin filament severing-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005903-&&-brush border-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:FLII				FLII	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLII	0.40519663	0.18778281	52	4	FALSE	FLII	FLII	187.9038462	0	52	0	0.75534373	FALSE	0	FLII	115754	0.055851
793124	taxon:9606	2.5786986	1.00E-04	180684	1902	growth hormone receptor	gene	biological_process-&-1&-GO:0006573-&&-valine metabolic process-%%-GO:0042977-&&-activation of JAK2 kinase activity-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0046449-&&-creatinine metabolic process-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0006549-&&-isoleucine metabolic process-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0060397-&&-JAK-STAT cascade involved in growth hormone signaling pathway-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006897-&&-endocytosis-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0044236-&&-multicellular organism metabolic process-%%-GO:0000255-&&-allantoin metabolic process-%%-GO:0006600-&&-creatine metabolic process-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0040018-&&-positive regulation of multicellular organism growth|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0016021-&&-integral component of membrane-%%-GO:0000932-&&-P-body-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0070195-&&-growth hormone receptor complex|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004896-&&-cytokine receptor activity-%%-GO:0017046-&&-peptide hormone binding-%%-GO:0070064-&&-proline-rich region binding	G:9606:GHR	GHR	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	GHR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GHR	0.38779251	0.13387755	52	4	FALSE	GHR	GHR	129.72	0	51	0	0.73688357	FALSE	1	GHR	158994	0.04872508
793175	taxon:9606	2.68504805	1.27E-04	180584	1902	glutamic-oxaloacetic transaminase 1	gene	biological_process-&-1&-GO:0055089-&&-fatty acid homeostasis-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006531-&&-aspartate metabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0019551-&&-glutamate catabolic process to 2-oxoglutarate-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006114-&&-glycerol biosynthetic process-%%-GO:0006533-&&-aspartate catabolic process-%%-GO:0006536-&&-glutamate metabolic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0019550-&&-glutamate catabolic process to aspartate-%%-GO:0006532-&&-aspartate biosynthetic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0006107-&&-oxaloacetate metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043679-&&-axon terminus-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0047801-&&-L-cysteine:2-oxoglutarate aminotransferase activity-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0004069-&&-L-aspartate:2-oxoglutarate aminotransferase activity-%%-GO:0080130-&&-L-phenylalanine:2-oxoglutarate aminotransferase activity-%%-GO:0004609-&&-phosphatidylserine decarboxylase activity-%%-GO:0031406-&&-carboxylic acid binding	G:9606:GOT1	GOT1	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa00360-&&-Phenylalanine metabolism-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa00400-&&-Phenylalanine, tyrosine and tryptophan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism	GOT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOT1	0.37243281	0.09351433	52	4	FALSE	GOT1	GOT1	72	0	52	0	0.71915866	FALSE	0	GOT1	134564	0.03543807
787016	taxon:9606	2.60059871	1.08E-04	180221	1902	integrin subunit beta 3	gene	biological_process-&-1&-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0016049-&&-cell growth-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0045715-&&-negative regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0016477-&&-cell migration-%%-GO:0007596-&&-blood coagulation-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0002576-&&-platelet degranulation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0032369-&&-negative regulation of lipid transport-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0042060-&&-wound healing-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0038027-&&-apolipoprotein A-I-mediated signaling pathway-%%-GO:0050748-&&-negative regulation of lipoprotein metabolic process-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0035295-&&-tube development-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0031527-&&-filopodium membrane-%%-GO:0034683-&&-integrin alphav-beta3 complex-%%-GO:0031528-&&-microvillus membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0035867-&&-alphav-beta3 integrin-IGF-1-IGF1R complex-%%-GO:0008305-&&-integrin complex-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0042470-&&-melanosome-%%-GO:0071062-&&-alphav-beta3 integrin-vitronectin complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0002020-&&-protease binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019960-&&-C-X3-C chemokine binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0001968-&&-fibronectin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0038132-&&-neuregulin binding-%%-GO:0001618-&&-virus receptor activity	G:9606:ITGB3	ITGB3	TRUE	KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04145-&&-Phagosome-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB3	0.38452684	0.11564626	51	4	FALSE	ITGB3	ITGB3	106.2653061	0	50	0	0.73323355	FALSE	1	ITGB3	133922	0.04224506
787023	taxon:9606	2.67669765	1.65E-04	180218	1902	integrin subunit beta 5	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0006936-&&-muscle contraction-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0034684-&&-integrin alphav-beta5 complex-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding	G:9606:ITGB5			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04145-&&-Phagosome-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB5	0.37359468	0.03826531	51	4	FALSE	ITGB5	ITGB5	74.81632653	0	50	0	0.72055039	FALSE	1	ITGB5	167470	0.03668646
787220	taxon:9606	2.48968016	2.05E-04	179837	1902	BCL2 family apoptosis regulator	gene	biological_process-&-1&-GO:0071806-&&-protein transmembrane transport-%%-GO:0034097-&&-response to cytokine-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0001709-&&-cell fate determination-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007275-&&-multicellular organism development-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1903378-&&-positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage|cellular_component-&-1&-GO:0097136-&&-Bcl-2 family protein complex-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051434-&&-BH3 domain binding-%%-GO:0015266-&&-protein channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:MCL1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05206-&&-MicroRNAs in cancer	MCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCL1	0.40165802	0.13520408	51	4	FALSE	MCL1	MCL1	151.8163265	0	50	0	0.75171997	FALSE	1	MCL1	253512	0.04712062
787418	taxon:9606	2.68394517	9.80E-05	179465	1902	NADH:ubiquinone oxidoreductase subunit A7	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005739-&&-mitochondrion-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFA7			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA7	0.37258585	0.08705882	51	4	FALSE	NDUFA7	NDUFA7	79.15686275	0	51	0	0.71934247	FALSE	0	NDUFA7	124156	0.03864915
787518	taxon:9606	2.54797542	1.39E-04	179296	1902	ATP binding cassette subfamily C member 1	gene	biological_process-&-1&-GO:0035461-&&-vitamin transmembrane transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0006855-&&-drug transmembrane transport-%%-GO:0042908-&&-xenobiotic transport-%%-GO:0006810-&&-transport-%%-GO:0099133-&&-ATP hydrolysis coupled anion transmembrane transport-%%-GO:0042493-&&-response to drug-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0015889-&&-cobalamin transport-%%-GO:0009235-&&-cobalamin metabolic process-%%-GO:0034775-&&-glutathione transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008559-&&-xenobiotic-transporting ATPase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0005215-&&-transporter activity-%%-GO:0015420-&&-cobalamin-transporting ATPase activity-%%-GO:0015431-&&-glutathione S-conjugate-exporting ATPase activity-%%-GO:0043225-&&-ATPase-coupled anion transmembrane transporter activity-%%-GO:0034634-&&-glutathione transmembrane transporter activity-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances	G:9606:ABCC1	ABCC1	TRUE	KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04977-&&-Vitamin digestion and absorption-%%-hsa02010-&&-ABC transporters-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa01523-&&-Antifolate resistance	ABCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCC1	0.39246846	0.06207483	51	4	FALSE	ABCC1	ABCC1	122.2040816	0	50	0	0.7420041	FALSE	1	ABCC1	176854	0.04274635
787567	taxon:9606	2.44351662	1.47E-04	179160	1902	NADH:ubiquinone oxidoreductase core subunit S2	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0006979-&&-response to oxidative stress|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0048038-&&-quinone binding-%%-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051287-&&-NAD binding	G:9606:NDUFS2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS2	0.40924624	0.20862745	51	4	FALSE	NDUFS2	NDUFS2	166.627451	0	51	0	0.7594139	FALSE	0	NDUFS2	261870	0.04746662
787692	taxon:9606	2.70883882	2.56E-04	178933	1902	plasminogen activator, urokinase receptor	gene	biological_process-&-1&-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0007165-&&-signal transduction-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0030162-&&-regulation of proteolysis-%%-GO:0006935-&&-chemotaxis-%%-GO:0038195-&&-urokinase plasminogen activator signaling pathway-%%-GO:2001268-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007596-&&-blood coagulation-%%-GO:0042730-&&-fibrinolysis-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0016255-&&-attachment of GPI anchor to protein-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0071438-&&-invadopodium membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0019898-&&-extrinsic component of membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0030377-&&-urokinase plasminogen activator receptor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004872-&&-receptor activity	G:9606:PLAUR			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04610-&&-Complement and coagulation cascades	PLAUR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLAUR	0.36916187	0.02636054	51	4	FALSE	PLAUR	PLAUR	60.67346939	0	50	0	0.71519353	FALSE	1	PLAUR	204064	0.03309886
787944	taxon:9606	2.54687254	6.59E-05	178528	1902	platelet activating factor acetylhydrolase 1b regulatory subunit 1	gene	biological_process-&-1&-GO:0021987-&&-cerebral cortex development-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0007281-&&-germ cell development-%%-GO:0009306-&&-protein secretion-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0001764-&&-neuron migration-%%-GO:0040019-&&-positive regulation of embryonic development-%%-GO:0031023-&&-microtubule organizing center organization-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0001675-&&-acrosome assembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007405-&&-neuroblast proliferation-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0021895-&&-cerebral cortex neuron differentiation-%%-GO:0042249-&&-establishment of planar polarity of embryonic epithelium-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0046469-&&-platelet activating factor metabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0060117-&&-auditory receptor cell development-%%-GO:0090102-&&-cochlea development-%%-GO:0007017-&&-microtubule-based process-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0021766-&&-hippocampus development-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0007097-&&-nuclear migration-%%-GO:0007611-&&-learning or memory-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0021540-&&-corpus callosum morphogenesis-%%-GO:0043622-&&-cortical microtubule organization-%%-GO:0017145-&&-stem cell division-%%-GO:0051661-&&-maintenance of centrosome location-%%-GO:0001961-&&-positive regulation of cytokine-mediated signaling pathway-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0001667-&&-ameboidal-type cell migration-%%-GO:0090176-&&-microtubule cytoskeleton organization involved in establishment of planar polarity-%%-GO:2000574-&&-regulation of microtubule motor activity-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0051660-&&-establishment of centrosome localization-%%-GO:0036035-&&-osteoclast development-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0016042-&&-lipid catabolic process|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005871-&&-kinesin complex-%%-GO:0005813-&&-centrosome-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031514-&&-motile cilium-%%-GO:0005938-&&-cell cortex-%%-GO:0000235-&&-astral microtubule-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031252-&&-cell leading edge-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005635-&&-nuclear envelope-%%-GO:0032420-&&-stereocilium-%%-GO:0031965-&&-nuclear membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0045505-&&-dynein intermediate chain binding-%%-GO:0008201-&&-heparin binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004623-&&-phospholipase A2 activity-%%-GO:0043274-&&-phospholipase binding	G:9606:PAFAH1B1	PAFAH1B1	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00565-&&-Ether lipid metabolism	PAFAH1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAFAH1B1	0.39263842	0.10034014	51	4	FALSE	PAFAH1B1	PAFAH1B1	124.0816327	0	50	0	0.74218791	FALSE	1	PAFAH1B1	105098	0.04305556
788018	taxon:9606	2.43059713	1.23E-04	178389	1902	phosphofructokinase, muscle	gene	biological_process-&-1&-GO:0093001-&&-glycolysis from storage polysaccharide through glucose-1-phosphate-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006096-&&-glycolytic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0051259-&&-protein oligomerization-%%-GO:0046835-&&-carbohydrate phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005945-&&-6-phosphofructokinase complex-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0097228-&&-sperm principal piece-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0070061-&&-fructose binding-%%-GO:0003872-&&-6-phosphofructokinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:PFKM			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa03018-&&-RNA degradation-%%-hsa00030-&&-Pentose phosphate pathway	PFKM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKM	0.41142153	0.12329932	51	4	FALSE	PFKM	PFKM	180.5510204	0	50	0	0.76156714	FALSE	1	PFKM	184666	0.05004441
788171	taxon:9606	2.52434221	1.24E-04	178128	1902	RAS like proto-oncogene A	gene	biological_process-&-1&-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0051665-&&-membrane raft localization-%%-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0006935-&&-chemotaxis-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0000910-&&-cytokinesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0006887-&&-exocytosis-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0043209-&&-myelin sheath-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0032154-&&-cleavage furrow-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0017022-&&-myosin binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031755-&&-Edg-2 lysophosphatidic acid receptor binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051117-&&-ATPase binding	G:9606:RALA			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer	RALA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RALA	0.3961428	0.08758503	51	4	FALSE	RALA	RALA	134.8367347	0	50	0	0.74594297	FALSE	1	RALA	160840	0.04465977
788182	taxon:9606	2.44446195	1.84E-04	178119	1902	RAP1B, member of RAS oncogene family	gene	biological_process-&-1&-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:2000301-&&-negative regulation of synaptic vesicle exocytosis-%%-GO:0030033-&&-microvillus assembly-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005811-&&-lipid particle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding-%%-GO:0032403-&&-protein complex binding	G:9606:RAP1B			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04720-&&-Long-term potentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04934-&&-Cushing syndrome-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04972-&&-Pancreatic secretion	RAP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP1B	0.40908798	0.06196078	51	4	FALSE	RAP1B	RAP1B	153.8431373	0	51	0	0.75925634	FALSE	0	RAP1B	254512	0.0439885
788260	taxon:9606	2.41326611	7.66E-05	177984	1902	ring finger protein 1	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001739-&&-sex chromatin-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:RING1				RING1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RING1	0.41437618	0.19557823	51	4	FALSE	RING1	RING1	196.9591837	0	50	0	0.76445565	FALSE	1	RING1	150552	0.05312619
788363	taxon:9606	2.41232078	8.24E-05	177801	1902	SEC13 homolog, nuclear pore and COPII coat complex component	gene	biological_process-&-1&-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0051028-&&-mRNA transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I|cellular_component-&-1&-GO:0031080-&&-nuclear pore outer ring-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0061700-&&-GATOR2 complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SEC13			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC13	0.41453857	0.12840136	51	4	FALSE	SEC13	SEC13	200.5510204	0	50	0	0.7646132	FALSE	1	SEC13	151244	0.05381927
788384	taxon:9606	2.46037498	2.56E-05	177763	1902	SS18, nBAF chromatin remodeling complex subunit	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071564-&&-npBAF complex-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0005515-&&-protein binding	G:9606:SS18			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	SS18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SS18	0.40644211	0.31921569	51	4	FALSE	SS18	SS18	243.4509804	0	51	0	0.75660417	FALSE	0	SS18	77706	0.07112211
788633	taxon:9606	2.52166378	3.29E-04	177283	1902	transcription factor AP-2 gamma	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008584-&&-male gonad development-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:TFAP2C				TFAP2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAP2C	0.39656357	0.04941176	51	4	FALSE	TFAP2C	TFAP2C	118.2352941	0	51	0	0.74638937	FALSE	0	TFAP2C	380318	0.03922873
788802	taxon:9606	2.64219316	5.14E-05	176841	1902	histone cell cycle regulator	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0031935-&&-regulation of chromatin silencing-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007369-&&-gastrulation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:HIRA				HIRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIRA	0.37847346	0.31137255	51	4	FALSE	HIRA	HIRA	219.8235294	0	51	0	0.72630114	FALSE	0	HIRA	113414	0.0942135
788981	taxon:9606	2.56404601	2.83E-05	176475	1902	lysine acetyltransferase 6A	gene	biological_process-&-1&-GO:0006323-&&-DNA packaging-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006334-&&-nucleosome assembly-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0006473-&&-protein acetylation-%%-GO:0016573-&&-histone acetylation-%%-GO:0090398-&&-cellular senescence|cellular_component-&-1&-GO:0070776-&&-MOZ/MORF histone acetyltransferase complex-%%-GO:0000786-&&-nucleosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding	G:9606:KAT6A			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	KAT6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT6A	0.3900086	0.31137255	51	4	FALSE	KAT6A	KAT6A	243.8039216	0	51	0	0.73932567	FALSE	0	KAT6A	97300	0.0871522
789250	taxon:9606	2.38805735	9.04E-05	175892	1902	insulin receptor substrate 2	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0030879-&&-mammary gland development-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0007411-&&-axon guidance-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0009749-&&-response to glucose-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:IRS2	IRS2	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04140-&&-Autophagy - animal-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	IRS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRS2	0.41875041	0.23607843	51	4	FALSE	IRS2	IRS2	211.1372549	0	51	0	0.76865711	FALSE	0	IRS2	185574	0.05470786
789293	taxon:9606	2.52197889	4.41E-05	175814	1902	DEAD-box helicase 23	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0000354-&&-cis assembly of pre-catalytic spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005682-&&-U5 snRNP-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008026-&&-ATP-dependent helicase activity	G:9606:DDX23			KEGG-&-1&-hsa03040-&&-Spliceosome	DDX23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX23	0.39651403	0.22588235	51	4	FALSE	DDX23	DDX23	194.7843137	0	51	0	0.74633685	FALSE	0	DDX23	97856	0.06409661
789354	taxon:9606	2.53883725	9.71E-05	175682	1902	autophagy related 12	gene	biological_process-&-1&-GO:0044804-&&-nucleophagy-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0045087-&&-innate immune response-%%-GO:0016236-&&-macroautophagy-%%-GO:0000422-&&-mitophagy-%%-GO:0006501-&&-C-terminal protein lipidation|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005829-&&-cytosol-%%-GO:0034274-&&-Atg12-Atg5-Atg16 complex|molecular_function-&-1&-GO:0019776-&&-Atg8 ligase activity-%%-GO:0005515-&&-protein binding	G:9606:ATG12			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04136-&&-Autophagy - other	ATG12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG12	0.3938811	0.03764706	51	4	FALSE	ATG12	ATG12	116.5686275	0	51	0	0.74352713	FALSE	0	ATG12	151330	0.04017068
789357	taxon:9606	2.55601071	1.15E-04	175673	1902	dual specificity tyrosine phosphorylation regulated kinase 1B	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0007520-&&-myoblast fusion|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:DYRK1B				DYRK1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYRK1B	0.39123467	0.07482993	51	4	FALSE	DYRK1B	DYRK1B	122.122449	0	50	0	0.74066488	FALSE	1	DYRK1B	149062	0.04332386
789476	taxon:9606	2.47487002	1.16E-04	175382	1902	protein disulfide isomerase family A member 4	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0009306-&&-protein secretion-%%-GO:0006457-&&-protein folding-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0042470-&&-melanosome-%%-GO:0009986-&&-cell surface-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PDIA4			KEGG-&-1&-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	PDIA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA4	0.40406162	0.14666667	51	4	FALSE	PDIA4	PDIA4	190.7058824	0	51	0	0.75418833	FALSE	0	PDIA4	207996	0.05741791
789664	taxon:9606	2.4477706	1.95E-04	174944	1902	ariadne RBR E3 ubiquitin protein ligase 2	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0048588-&&-developmental cell growth|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:ARIH2				ARIH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARIH2	0.40853502	0.10119048	51	4	FALSE	ARIH2	ARIH2	172.3265306	0	50	0	0.7587049	FALSE	1	ARIH2	268210	0.04948393
789710	taxon:9606	2.55664093	2.36E-04	174845	1902	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5	gene	biological_process-&-1&-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0009615-&&-response to virus-%%-GO:0061462-&&-protein localization to lysosome-%%-GO:0016236-&&-macroautophagy-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0019079-&&-viral genome replication-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0008361-&&-regulation of cell size-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0071986-&&-Ragulator complex-%%-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:LAMTOR5			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	LAMTOR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMTOR5	0.39113823	0.03372549	51	4	FALSE	LAMTOR5	LAMTOR5	101	0	51	0	0.74055984	FALSE	0	LAMTOR5	235118	0.03617309
789739	taxon:9606	2.33259808	8.51E-05	174788	1902	DnaJ heat shock protein family (Hsp40) member B6	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0045109-&&-intermediate filament organization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001671-&&-ATPase activator activity	G:9606:DNAJB6				DNAJB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB6	0.42870652	0.14666667	51	4	FALSE	DNAJB6	DNAJB6	232.5882353	0	51	0	0.77790032	FALSE	0	DNAJB6	194970	0.05526355
789830	taxon:9606	2.50338743	1.38E-04	174550	1902	growth arrest and DNA damage inducible gamma	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0006950-&&-response to stress-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0030154-&&-cell differentiation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GADD45G			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GADD45G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GADD45G	0.39945875	0.0745098	51	4	FALSE	GADD45G	GADD45G	127.0392157	0	51	0	0.74943543	FALSE	0	GADD45G	185670	0.04053123
789959	taxon:9606	2.44871593	8.22E-05	174240	1902	polynucleotide kinase 3'-phosphatase	gene	biological_process-&-1&-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0098506-&&-polynucleotide 3' dephosphorylation-%%-GO:0006281-&&-DNA repair-%%-GO:0016311-&&-dephosphorylation-%%-GO:0098504-&&-DNA 3' dephosphorylation involved in DNA repair-%%-GO:0009314-&&-response to radiation-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0046939-&&-nucleotide phosphorylation-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000718-&&-nucleotide-excision repair, DNA damage removal-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019201-&&-nucleotide kinase activity-%%-GO:0046403-&&-polynucleotide 3'-phosphatase activity-%%-GO:0046404-&&-ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0017076-&&-purine nucleotide binding-%%-GO:0004519-&&-endonuclease activity	G:9606:PNKP				PNKP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNKP	0.4083773	0.11843137	51	4	FALSE	PNKP	PNKP	176.8431373	0	51	0	0.75854735	FALSE	0	PNKP	152394	0.05082136
790199	taxon:9606	2.42461005	9.27E-05	173657	1902	mitochondrial ribosomal protein S27	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MRPS27				MRPS27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS27	0.41243746	0.23137255	51	4	FALSE	MRPS27	MRPS27	228.3137255	0	51	0	0.76256499	FALSE	0	MRPS27	182128	0.0626794
790315	taxon:9606	2.58106192	6.18E-05	173340	1902	RNA polymerase I subunit A	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:1904750-&&-negative regulation of protein localization to nucleolus-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0005736-&&-DNA-directed RNA polymerase I complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR1A			KEGG-&-1&-hsa03020-&&-RNA polymerase	POLR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR1A	0.38743743	0.12078431	51	4	FALSE	POLR1A	POLR1A	130.5490196	0	51	0	0.73648968	FALSE	0	POLR1A	104676	0.0490454
790329	taxon:9606	2.37025366	5.84E-05	173300	1902	SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1	gene	biological_process-&-1&-GO:0006955-&&-immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0046061-&&-dATP catabolic process-%%-GO:0006203-&&-dGTP catabolic process-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008832-&&-dGTPase activity-%%-GO:0032567-&&-dGTP binding-%%-GO:0003676-&&-nucleic acid binding	G:9606:SAMHD1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection	SAMHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAMHD1	0.42189577	0.18792517	51	4	FALSE	SAMHD1	SAMHD1	239.4693878	0	50	0	0.77162439	FALSE	1	SAMHD1	137368	0.06023874
790433	taxon:9606	2.49724279	8.37E-05	173003	1902	apoptosis antagonizing transcription factor	gene	biological_process-&-1&-GO:0042254-&&-ribosome biogenesis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0042985-&&-negative regulation of amyloid precursor protein biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032929-&&-negative regulation of superoxide anion generation-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043522-&&-leucine zipper domain binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:AATF				AATF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AATF	0.40044164	0.13176471	51	4	FALSE	AATF	AATF	163.5882353	0	51	0	0.75045953	FALSE	0	AATF	143068	0.05130524
790535	taxon:9606	2.53174728	5.46E-05	172548	1902	eukaryotic translation initiation factor 3 subunit K	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3K				EIF3K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3K	0.39498413	0.21333333	51	4	FALSE	EIF3K	EIF3K	148.4705882	0	51	0	0.74470879	FALSE	0	EIF3K	109168	0.0504116
790705	taxon:9606	2.44556483	5.37E-05	171420	1902	cleavage and polyadenylation specific factor 1	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006388-&&-tRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex|molecular_function-&-1&-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:CPSF1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CPSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPSF1	0.40890349	0.18452381	51	4	FALSE	CPSF1	CPSF1	248.0612245	0	50	0	0.75907253	FALSE	1	CPSF1	134132	0.07060655
790718	taxon:9606	2.4526548	9.95E-05	171398	1902	Sec61 translocon alpha 1 subunit	gene	biological_process-&-1&-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0045047-&&-protein targeting to ER-%%-GO:0006620-&&-posttranslational protein targeting to membrane-%%-GO:0016049-&&-cell growth-%%-GO:0039019-&&-pronephric nephron development-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0034341-&&-response to interferon-gamma|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding	G:9606:SEC61A1			KEGG-&-1&-hsa03060-&&-Protein export-%%-hsa04145-&&-Phagosome-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC61A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC61A1	0.40772146	0.12755102	51	4	FALSE	SEC61A1	SEC61A1	176.2040816	0	50	0	0.75789087	FALSE	1	SEC61A1	187246	0.05094076
791033	taxon:9606	2.64361115	9.94E-05	170292	1902	Meckel syndrome, type 1	gene	biological_process-&-1&-GO:2000095-&&-regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:1990403-&&-embryonic brain development-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0010669-&&-epithelial structure maintenance-%%-GO:0060322-&&-head development-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0060122-&&-inner ear receptor stereocilium organization-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0061009-&&-common bile duct development-%%-GO:0060271-&&-cilium assembly-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0001843-&&-neural tube closure-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:1901620-&&-regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0044458-&&-motile cilium assembly-%%-GO:1905515-&&-non-motile cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0016020-&&-membrane-%%-GO:0036038-&&-MKS complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MKS1				MKS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKS1	0.37827046	0.06823529	51	4	FALSE	MKS1	MKS1	93.88235294	0	51	0	0.72606481	FALSE	0	MKS1	125702	0.04109907
791224	taxon:9606	2.61635418	4.03E-05	169672	1902	histone deacetylase 8	gene	biological_process-&-1&-GO:0071922-&&-regulation of cohesin loading-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0032204-&&-regulation of telomere maintenance-%%-GO:0006333-&&-chromatin assembly or disassembly-%%-GO:0006325-&&-chromatin organization-%%-GO:0070932-&&-histone H3 deacetylation|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0032041-&&-NAD-dependent histone deacetylase activity (H3-K14 specific)-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:HDAC8			KEGG-&-1&-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HDAC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HDAC8	0.38221125	0.22588235	51	4	FALSE	HDAC8	HDAC8	211.5882353	0	51	0	0.73060764	FALSE	0	HDAC8	111948	0.08625212
791254	taxon:9606	2.45942965	1.54E-04	169516	1902	tripartite motif containing 39	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM39				TRIM39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM39	0.40659833	0.09013605	51	4	FALSE	TRIM39	TRIM39	154.8163265	0	50	0	0.75676172	FALSE	1	TRIM39	212912	0.0454922
791273	taxon:9606	2.53820703	1.09E-04	169419	1902	metastasis associated 1 family member 3	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0016575-&&-histone deacetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016581-&&-NuRD complex-%%-GO:0008278-&&-cohesin complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:MTA3				MTA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTA3	0.3939789	0.16941176	51	5	FALSE	MTA3	MTA3	131.6862745	0	51	0	0.74363216	FALSE	0	MTA3	166550	0.04490203
791432	taxon:9606	2.33259808	8.51E-05	168671	1902	transmembrane protein 135	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0032094-&&-response to food-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:0007031-&&-peroxisome organization|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0031966-&&-mitochondrial membrane	G:9606:TMEM135				TMEM135	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM135	0.42870652	0.14666667	51	4	FALSE	TMEM135	TMEM135	232.5882353	0	51	0	0.77790032	FALSE	0	TMEM135	194970	0.05526355
791865	taxon:9606	2.47502757	5.60E-05	182962	1902	acetyl-CoA acetyltransferase 1	gene	biological_process-&-1&-GO:0072229-&&-metanephric proximal convoluted tubule development-%%-GO:0046356-&&-acetyl-CoA catabolic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006085-&&-acetyl-CoA biosynthetic process-%%-GO:0015936-&&-coenzyme A metabolic process-%%-GO:0007420-&&-brain development-%%-GO:1902860-&&-propionyl-CoA biosynthetic process-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1902224-&&-ketone body metabolic process-%%-GO:0006550-&&-isoleucine catabolic process-%%-GO:0001889-&&-liver development-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0042594-&&-response to starvation-%%-GO:0046952-&&-ketone body catabolic process-%%-GO:0046951-&&-ketone body biosynthetic process-%%-GO:0015937-&&-coenzyme A biosynthetic process-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0016830-&&-carbon-carbon lyase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003985-&&-acetyl-CoA C-acetyltransferase activity-%%-GO:0050662-&&-coenzyme binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0016885-&&-ligase activity, forming carbon-carbon bonds	G:9606:ACAT1			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00071-&&-Fatty acid degradation-%%-hsa00072-&&-Synthesis and degradation of ketone bodies-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	ACAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAT1	0.4040359	0.1547619	51	4	FALSE	ACAT1	ACAT1	219.755102	0	50	0	0.75416207	FALSE	1	ACAT1	126344	0.06599396
792537	taxon:9606	2.54450922	2.73E-04	181836	1902	caspase 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0050717-&&-positive regulation of interleukin-1 alpha secretion-%%-GO:0033198-&&-response to ATP-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:1901998-&&-toxin transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0032611-&&-interleukin-1 beta production-%%-GO:0070269-&&-pyroptosis-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051882-&&-mitochondrial depolarization-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0016485-&&-protein processing-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0097300-&&-programmed necrotic cell death-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0072558-&&-NLRP1 inflammasome complex-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0072557-&&-IPAF inflammasome complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0097169-&&-AIM2 inflammasome complex|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process	G:9606:CASP1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05133-&&-Pertussis-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis	CASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP1	0.3930031	0.06462585	51	4	FALSE	CASP1	CASP1	108.6326531	0	50	0	0.7425818	FALSE	1	CASP1	280338	0.03773344
792553	taxon:9606	2.44966126	4.55E-04	181823	1902	catalase	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070542-&&-response to fatty acid-%%-GO:0080184-&&-response to phenylpropanoid-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0010288-&&-response to lead ion-%%-GO:0032868-&&-response to insulin-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045471-&&-response to ethanol-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0014854-&&-response to inactivity-%%-GO:0020027-&&-hemoglobin metabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006195-&&-purine nucleotide catabolic process-%%-GO:0009060-&&-aerobic respiration-%%-GO:0042493-&&-response to drug-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0033189-&&-response to vitamin A-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001657-&&-ureteric bud development-%%-GO:0033197-&&-response to vitamin E-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0009642-&&-response to light intensity-%%-GO:0009650-&&-UV protection-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0051262-&&-protein tetramerization-%%-GO:0010193-&&-response to ozone-%%-GO:0033591-&&-response to L-ascorbic acid-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0014823-&&-response to activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004096-&&-catalase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0050661-&&-NADP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004046-&&-aminoacylase activity-%%-GO:0016684-&&-oxidoreductase activity, acting on peroxide as acceptor-%%-GO:0016209-&&-antioxidant activity-%%-GO:0020037-&&-heme binding	G:9606:CAT	CAT	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species	CAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAT	0.40821971	0.1037415	51	4	FALSE	CAT	CAT	147.3469388	0	50	0	0.75838979	FALSE	1	CAT	428492	0.04228201
792573	taxon:9606	2.57365685	1.49E-04	181794	1902	cyclin C	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:1901409-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:CCNC				CCNC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNC	0.38855219	0.20705882	51	4	FALSE	CCNC	CCNC	108.4313726	0	51	0	0.73772386	FALSE	0	CCNC	158720	0.03981401
792606	taxon:9606	2.51299827	1.24E-04	181728	1902	dishevelled segment polarity protein 3	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0038031-&&-non-canonical Wnt signaling pathway via JNK cascade-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0042493-&&-response to drug-%%-GO:0035567-&&-non-canonical Wnt signaling pathway|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005829-&&-cytosol-%%-GO:1990909-&&-Wnt signalosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0002020-&&-protease binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:DVL3			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	DVL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DVL3	0.39793103	0.09778912	51	4	FALSE	DVL3	DVL3	130.3673469	0	50	0	0.74783362	FALSE	1	DVL3	171338	0.04217202
792821	taxon:9606	2.61572396	9.32E-05	181308	1902	enolase 3	gene	biological_process-&-1&-GO:0007568-&&-aging-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0000015-&&-phosphopyruvate hydratase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004634-&&-phosphopyruvate hydratase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:ENO3			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa03018-&&-RNA degradation	ENO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENO3	0.38230334	0.23214286	51	4	FALSE	ENO3	ENO3	104.2653061	0	50	0	0.73071267	FALSE	1	ENO3	120494	0.04254894
792935	taxon:9606	2.52308177	1.61E-04	181119	1902	Fanconi anemia complementation group C	gene	biological_process-&-1&-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006281-&&-DNA repair-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FANCC			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCC	0.3963407	0.08156863	51	4	FALSE	FANCC	FANCC	133.8039216	0	51	0	0.74615304	FALSE	0	FANCC	213588	0.04440753
793116	taxon:9606	2.44903104	9.95E-05	180700	1902	glial fibrillary acidic protein	gene	biological_process-&-1&-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0043254-&&-regulation of protein complex assembly|cellular_component-&-1&-GO:0005764-&&-lysosome-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:GFAP			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway	GFAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFAP	0.40832476	0.09013605	51	4	FALSE	GFAP	GFAP	152.4285714	0	50	0	0.75849483	FALSE	1	GFAP	170252	0.04390901
787136	taxon:9606	2.46699228	4.20E-05	180006	1902	inhibitor of growth family member 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010941-&&-regulation of cell death-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:ING1				ING1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ING1	0.4053519	0.21453901	50	4	FALSE	ING1	ING1	217.6041667	0	49	0	0.75550129	FALSE	1	ING1	99502	0.06428484
787202	taxon:9606	2.42650071	1.04E-04	179869	1902	microtubule associated protein 2	gene	biological_process-&-1&-GO:0031175-&&-neuron projection development-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0021954-&&-central nervous system neuron development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043005-&&-neuron projection-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0002162-&&-dystroglycan binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MAP2	MAP2	TRUE		MAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2	0.4121161	0.10815603	50	4	FALSE	MAP2	MAP2	162.2291667	0	49	0	0.76224988	FALSE	1	MAP2	170388	0.04492151
787304	taxon:9606	2.43548133	2.52E-04	179689	1902	kinesin light chain 1	gene	biological_process-&-1&-GO:0007018-&&-microtubule-based movement-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0035617-&&-stress granule disassembly-%%-GO:0016032-&&-viral process-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0035418-&&-protein localization to synapse|cellular_component-&-1&-GO:0005871-&&-kinesin complex-%%-GO:0030424-&&-axon-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0015631-&&-tubulin binding	G:9606:KLC1			KEGG-&-1&-hsa05132-&&-Salmonella infection	KLC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLC1	0.41059645	0.10638298	50	4	FALSE	KLC1	KLC1	152.0833333	0	49	0	0.76075311	FALSE	1	KLC1	262172	0.0425
787319	taxon:9606	2.4279187	3.21E-05	179669	1902	keratin 5	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0045095-&&-keratin filament-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:KRT5				KRT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT5	0.41187541	0.23020408	50	4	FALSE	KRT5	KRT5	251.68	0	50	0	0.76201355	FALSE	0	KRT5	121966	0.06981415
787348	taxon:9606	2.4958248	1.45E-04	179615	1902	LIM and SH3 protein 1	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006811-&&-ion transport|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030864-&&-cortical actin cytoskeleton|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0015075-&&-ion transmembrane transporter activity-%%-GO:0045296-&&-cadherin binding	G:9606:LASP1				LASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LASP1	0.40066915	0.05306122	50	4	FALSE	LASP1	LASP1	134.18	0	50	0	0.75069587	FALSE	0	LASP1	184368	0.04230648
787495	taxon:9606	2.43878998	1.37E-04	179343	1902	afadin, adherens junction formation factor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0007165-&&-signal transduction-%%-GO:0034332-&&-adherens junction organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005912-&&-adherens junction|molecular_function-&-1&-GO:0017016-&&-Ras GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:AFDN			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04530-&&-Tight junction-%%-hsa04520-&&-Adherens junction	AFDN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AFDN	0.41003941	0.14040816	50	4	FALSE	AFDN	AFDN	225.72	0	50	0	0.76020167	FALSE	0	AFDN	239718	0.06376378
787947	taxon:9606	2.52497243	6.46E-05	178527	1902	platelet activating factor acetylhydrolase 1b catalytic subunit 2	gene	biological_process-&-1&-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0007420-&&-brain development-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004623-&&-phospholipase A2 activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003847-&&-1-alkyl-2-acetylglycerophosphocholine esterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0047179-&&-platelet-activating factor acetyltransferase activity	G:9606:PAFAH1B2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00565-&&-Ether lipid metabolism	PAFAH1B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAFAH1B2	0.39604393	0.10549645	50	4	FALSE	PAFAH1B2	PAFAH1B2	152.4375	0	49	0	0.74583793	FALSE	1	PAFAH1B2	117028	0.0508325
788136	taxon:9606	2.47171892	1.32E-04	178178	1902	ATP binding cassette subfamily D member 3	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0007031-&&-peroxisome organization-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0042493-&&-response to drug-%%-GO:0015910-&&-peroxisomal long-chain fatty acid import-%%-GO:0042760-&&-very long-chain fatty acid catabolic process|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005782-&&-peroxisomal matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005324-&&-long-chain fatty acid transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association	G:9606:ABCD3			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa02010-&&-ABC transporters	ABCD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCD3	0.40457675	0.07003546	50	4	FALSE	ABCD3	ABCD3	166.2916667	0	49	0	0.75471351	FALSE	1	ABCD3	240804	0.04976297
788313	taxon:9606	2.38443359	1.21E-04	177901	1902	S100 calcium binding protein A8	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0018119-&&-peptidyl-cysteine S-nitrosylation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0032119-&&-sequestering of zinc ion-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0050832-&&-defense response to fungus-%%-GO:0032602-&&-chemokine production-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0010043-&&-response to zinc ion-%%-GO:0002793-&&-positive regulation of peptide secretion-%%-GO:0014002-&&-astrocyte development-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0045471-&&-response to ethanol-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006914-&&-autophagy-%%-GO:0006954-&&-inflammatory response-%%-GO:0070488-&&-neutrophil aggregation-%%-GO:0042060-&&-wound healing-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0001816-&&-cytokine production-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0035662-&&-Toll-like receptor 4 binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050544-&&-arachidonic acid binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0008017-&&-microtubule binding	G:9606:S100A8			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	S100A8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A8	0.41938681	0.09574468	50	4	FALSE	S100A8	S100A8	207.8541667	0	49	0	0.76926107	FALSE	1	S100A8	217976	0.0533978
788404	taxon:9606	2.47691823	8.55E-05	177729	1902	striatin	gene	biological_process-&-1&-GO:0007626-&&-locomotory behavior-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0016358-&&-dendrite development-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016020-&&-membrane-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding	G:9606:STRN				STRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRN	0.4037275	0.18612245	50	4	FALSE	STRN	STRN	152.72	0	50	0	0.75384696	FALSE	0	STRN	146174	0.04619855
788573	taxon:9606	2.44351662	6.39E-05	177415	1902	TATA-box binding protein associated factor 6	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TAF6			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF6	0.40924624	0.24556738	50	4	FALSE	TAF6	TAF6	170.1041667	0	49	0	0.7594139	FALSE	1	TAF6	135806	0.04826428
788595	taxon:9606	2.47565779	1.43E-04	177375	1902	transcription elongation factor A2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006354-&&-DNA-templated transcription, elongation-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation|cellular_component-&-1&-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TCEA2				TCEA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEA2	0.40393305	0.06204082	50	4	FALSE	TCEA2	TCEA2	142.84	0	50	0	0.75405703	FALSE	0	TCEA2	212922	0.0431649
788602	taxon:9606	2.48715929	2.31E-04	177360	1902	transcription factor 12	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0006955-&&-immune response-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070888-&&-E-box binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0046332-&&-SMAD binding	G:9606:TCF12				TCF12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF12	0.40206512	0.09131206	50	4	FALSE	TCF12	TCF12	139.3958333	0	49	0	0.75214012	FALSE	1	TCF12	260216	0.0428134
788747	taxon:9606	2.38837246	1.15E-04	177045	1902	TTK protein kinase	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1903096-&&-protein localization to meiotic spindle midzone-%%-GO:0033316-&&-meiotic spindle assembly checkpoint-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0051304-&&-chromosome separation-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0007051-&&-spindle organization-%%-GO:0016321-&&-female meiosis chromosome segregation-%%-GO:0034501-&&-protein localization to kinetochore-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0016020-&&-membrane-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:TTK			KEGG-&-1&-hsa04110-&&-Cell cycle	TTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTK	0.41869516	0.15957447	50	4	FALSE	TTK	TTK	198.8541667	0	49	0	0.76860459	FALSE	1	TTK	191152	0.0514205
788845	taxon:9606	2.51110761	7.57E-05	176760	1902	upstream transcription factor 1	gene	biological_process-&-1&-GO:0000430-&&-regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000432-&&-positive regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0009411-&&-response to UV-%%-GO:0019086-&&-late viral transcription-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045990-&&-carbon catabolite regulation of transcription|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016589-&&-NURF complex-%%-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding	G:9606:USF1				USF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USF1	0.39823064	0.1143617	50	4	FALSE	USF1	USF1	147.9791667	0	49	0	0.74814873	FALSE	1	USF1	126708	0.04779214
788890	taxon:9606	2.53631637	1.15E-04	176664	1902	X-prolyl aminopeptidase 1	gene	biological_process-&-1&-GO:0010815-&&-bradykinin catabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004177-&&-aminopeptidase activity	G:9606:XPNPEP1				XPNPEP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPNPEP1	0.39427258	0.09632653	50	4	FALSE	XPNPEP1	XPNPEP1	117.42	0	50	0	0.74394727	FALSE	0	XPNPEP1	144690	0.03987763
789283	taxon:9606	2.68299984	1.03E-04	175828	1902	RecQ like helicase 5	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0051304-&&-chromosome separation-%%-GO:2000042-&&-negative regulation of double-strand break repair via homologous recombination-%%-GO:0035690-&&-cellular response to drug-%%-GO:0051301-&&-cell division-%%-GO:0006260-&&-DNA replication-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0072757-&&-cellular response to camptothecin-%%-GO:0034244-&&-negative regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006281-&&-DNA repair-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1990414-&&-replication-born double-strand break repair via sister chromatid exchange|cellular_component-&-1&-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005737-&&-cytoplasm-%%-GO:0005694-&&-chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0009378-&&-four-way junction helicase activity	G:9606:RECQL5				RECQL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RECQL5	0.37271713	0.15673469	50	4	FALSE	RECQL5	RECQL5	165.72	0	50	0	0.71950003	FALSE	0	RECQL5	171568	0.08003868
789290	taxon:9606	2.49346148	1.07E-04	175816	1902	tight junction protein 2	gene	biological_process-&-1&-GO:0090559-&&-regulation of membrane permeability-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:2001205-&&-negative regulation of osteoclast development-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0035329-&&-hippo signaling-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0071847-&&-TNFSF11-mediated signaling pathway-%%-GO:0050892-&&-intestinal absorption|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005912-&&-adherens junction-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0045296-&&-cadherin binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:TJP2			KEGG-&-1&-hsa04530-&&-Tight junction-%%-hsa05110-&&-Vibrio cholerae infection	TJP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TJP2	0.40104891	0.11265306	50	4	FALSE	TJP2	TJP2	166.58	0	50	0	0.75108975	FALSE	0	TJP2	166674	0.05175264
789519	taxon:9606	2.38711202	3.64E-04	175272	1902	SUMO1 activating enzyme subunit 1	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0016925-&&-protein sumoylation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0031510-&&-SUMO activating enzyme complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0019948-&&-SUMO activating enzyme activity-%%-GO:0043008-&&-ATP-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004839-&&-ubiquitin activating enzyme activity	G:9606:SAE1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	SAE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAE1	0.41891624	0.11510204	50	4	FALSE	SAE1	SAE1	181.34	0	50	0	0.76881466	FALSE	0	SAE1	390398	0.0468666
789670	taxon:9606	2.56420356	5.97E-05	174929	1902	microspherule protein 1	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006464-&&-cellular protein modification process|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005844-&&-polysome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0031011-&&-Ino80 complex-%%-GO:0005730-&&-nucleolus-%%-GO:0030425-&&-dendrite-%%-GO:0043204-&&-perikaryon-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0034046-&&-poly(G) binding-%%-GO:0005515-&&-protein binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)	G:9606:MCRS1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	MCRS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCRS1	0.38998464	0.07755102	50	4	FALSE	MCRS1	MCRS1	120.32	0	50	0	0.73929941	FALSE	0	MCRS1	104396	0.04320517
789805	taxon:9606	2.43831732	5.89E-05	174617	1902	A-kinase anchoring protein 8	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0015031-&&-protein transport-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033127-&&-regulation of histone phosphorylation-%%-GO:0044839-&&-cell cycle G2/M phase transition-%%-GO:0007165-&&-signal transduction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0016363-&&-nuclear matrix-%%-GO:0001939-&&-female pronucleus-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding	G:9606:AKAP8				AKAP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP8	0.41011889	0.16408163	50	4	FALSE	AKAP8	AKAP8	246.32	0	50	0	0.76028045	FALSE	0	AKAP8	154176	0.06927968
789942	taxon:9606	2.61083977	1.17E-04	174292	1902	lysine demethylase 5B	gene	biological_process-&-1&-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000864-&&-regulation of estradiol secretion-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0007338-&&-single fertilization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0034721-&&-histone H3-K4 demethylation, trimethyl-H3-K4-specific-%%-GO:0060992-&&-response to fungicide-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048511-&&-rhythmic process-%%-GO:0034720-&&-histone H3-K4 demethylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0009791-&&-post-embryonic development-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0061038-&&-uterus morphogenesis-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0060763-&&-mammary duct terminal end bud growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0034647-&&-histone demethylase activity (H3-trimethyl-K4 specific)-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0005515-&&-protein binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0032453-&&-histone demethylase activity (H3-K4 specific)-%%-GO:0034648-&&-histone demethylase activity (H3-dimethyl-K4 specific)-%%-GO:0008270-&&-zinc ion binding	G:9606:KDM5B				KDM5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM5B	0.38301853	0.23346939	50	4	FALSE	KDM5B	KDM5B	178.56	0	50	0	0.73152671	FALSE	0	KDM5B	184190	0.07160177
790064	taxon:9606	2.67433433	1.15E-04	173965	1902	chromosome 14 open reading frame 1	gene	biological_process-&-1&-GO:0006696-&&-ergosterol biosynthetic process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0003674-&&-molecular_function	G:9606:C14orf1				C14orf1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C14orf1	0.37392483	0.01306122	50	4	FALSE	C14orf1	C14orf1	70.18	0	50	0	0.72094428	FALSE	0	C14orf1	128182	0.03375969
790119	taxon:9606	2.51378604	1.36E-04	173840	1902	zinc fingers and homeoboxes 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:ZHX1				ZHX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZHX1	0.39780633	0.09397163	50	4	FALSE	ZHX1	ZHX1	138.7291667	0	49	0	0.74770233	FALSE	1	ZHX1	167440	0.04479773
790317	taxon:9606	2.59461163	4.53E-05	173333	1902	EEF1A lysine methyltransferase 3	gene	biological_process-&-1&-GO:0032259-&&-methylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity	G:9606:EEF1AKMT3				EEF1AKMT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1AKMT3	0.38541414	0.13061224	50	4	FALSE	EEF1AKMT3	EEF1AKMT3	137.74	0	50	0	0.7342314	FALSE	0	EEF1AKMT3	88608	0.05350952
790754	taxon:9606	2.44587994	4.46E-05	171325	1902	MRT4 homolog, ribosome maturation factor	gene	biological_process-&-1&-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006364-&&-rRNA processing-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MRTO4				MRTO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRTO4	0.40885081	0.26612245	50	4	FALSE	MRTO4	MRTO4	228.7	0	50	0	0.75902001	FALSE	0	MRTO4	103814	0.06522533
790764	taxon:9606	2.44036553	1.46E-04	171295	1902	importin 11	gene	biological_process-&-1&-GO:0006610-&&-ribosomal protein import into nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:IPO11				IPO11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO11	0.40977468	0.09795918	50	4	FALSE	IPO11	IPO11	166.82	0	50	0	0.75993908	FALSE	0	IPO11	230670	0.04719909
790969	taxon:9606	2.44997637	8.89E-05	170560	1902	pentatricopeptide repeat domain 3	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0006417-&&-regulation of translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding	G:9606:PTCD3				PTCD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTCD3	0.4081672	0.23673469	50	4	FALSE	PTCD3	PTCD3	224.16	0	50	0	0.75833727	FALSE	0	PTCD3	162676	0.06434109
790979	taxon:9606	2.65085867	1.33E-04	170521	1902	WDYHV motif containing 1	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070773-&&-protein-N-terminal glutamine amidohydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:WDYHV1				WDYHV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDYHV1	0.37723626	0.03346939	50	4	FALSE	WDYHV1	WDYHV1	82.62	0	50	0	0.72485689	FALSE	0	WDYHV1	149198	0.03730072
790990	taxon:9606	2.61808729	1.68E-04	170482	1902	cell division cycle associated 8	gene	biological_process-&-1&-GO:0051276-&&-chromosome organization-%%-GO:0016925-&&-protein sumoylation-%%-GO:0051301-&&-cell division-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007080-&&-mitotic metaphase plate congression|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005829-&&-cytosol-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0016604-&&-nuclear body-%%-GO:0051233-&&-spindle midzone-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0010369-&&-chromocenter-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CDCA8				CDCA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDCA8	0.38195824	0.1108156	50	4	FALSE	CDCA8	CDCA8	183.5208333	0	49	0	0.73031879	FALSE	1	CDCA8	287176	0.07436613
791308	taxon:9606	2.39089334	3.61E-05	169254	1902	mitochondrial ribosomal protein S22	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS22				MRPS22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS22	0.41825371	0.29142857	50	4	FALSE	MRPS22	MRPS22	270.04	0	50	0	0.76818444	FALSE	0	MRPS22	123814	0.07012205
791395	taxon:9606	2.54025524	1.21E-04	168819	1902	sorting nexin 6	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0016050-&&-vesicle organization-%%-GO:1903593-&&-regulation of histamine secretion by mast cell-%%-GO:0006897-&&-endocytosis-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0030905-&&-retromer, tubulation complex-%%-GO:0005829-&&-cytosol-%%-GO:0097422-&&-tubular endosome-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034452-&&-dynactin binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:SNX6			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX6	0.39366123	0.09308511	50	4	FALSE	SNX6	SNX6	109.6875	0	49	0	0.74329079	FALSE	1	SNX6	159540	0.03767045
791475	taxon:9606	2.58074681	1.58E-04	168480	1902	salvador family WW domain containing protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0035329-&&-hippo signaling-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060575-&&-intestinal epithelial cell differentiation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050821-&&-protein stabilization-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0001942-&&-hair follicle development-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:SAV1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	SAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAV1	0.38748474	0.09485816	50	4	FALSE	SAV1	SAV1	117.3541667	0	49	0	0.7365422	FALSE	1	SAV1	189798	0.04410336
791502	taxon:9606	2.6932409	6.77E-05	168357	1902	nuclear receptor binding SET domain protein 1	gene	biological_process-&-1&-GO:0010452-&&-histone H3-K36 methylation-%%-GO:0000414-&&-regulation of histone H3-K36 methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0034770-&&-histone H4-K20 methylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1903025-&&-regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0016571-&&-histone methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0046975-&&-histone methyltransferase activity (H3-K36 specific)-%%-GO:0042799-&&-histone methyltransferase activity (H4-K20 specific)-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:NSD1			KEGG-&-1&-hsa00310-&&-Lysine degradation	NSD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSD1	0.37129987	0.24653061	50	4	FALSE	NSD1	NSD1	207.6	0	50	0	0.71779318	FALSE	0	NSD1	176098	0.10277365
791645	taxon:9606	2.42240429	1.95E-04	167593	1902	thioredoxin domain containing 5	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006457-&&-protein folding-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:TXNDC5			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	TXNDC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNDC5	0.41281301	0.11183673	50	4	FALSE	TXNDC5	TXNDC5	184.12	0	50	0	0.76293262	FALSE	0	TXNDC5	323860	0.05049396
791861	taxon:9606	2.54340633	8.19E-05	182966	1902	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	gene	biological_process-&-1&-GO:0019254-&&-carnitine metabolic process, CoA-linked-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase-%%-GO:0045329-&&-carnitine biosynthetic process-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051791-&&-medium-chain fatty acid metabolic process-%%-GO:0051793-&&-medium-chain fatty acid catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016607-&&-nuclear speck-%%-GO:0005739-&&-mitochondrion-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003995-&&-acyl-CoA dehydrogenase activity-%%-GO:0070991-&&-medium-chain-acyl-CoA dehydrogenase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:ACADM			KEGG-&-1&-hsa00410-&&-beta-Alanine metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	ACADM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACADM	0.39317351	0.18705674	50	4	FALSE	ACADM	ACADM	140.7083333	0	49	0	0.74276561	FALSE	1	ACADM	114940	0.04850092
792150	taxon:9606	2.69828265	1.26E-04	182518	1902	activin A receptor type 1	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0061445-&&-endocardial cushion cell fate commitment-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0001707-&&-mesoderm formation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0007281-&&-germ cell development-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:2000017-&&-positive regulation of determination of dorsal identity-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0030278-&&-regulation of ossification-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003274-&&-endocardial cushion fusion-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0060923-&&-cardiac muscle cell fate commitment-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0032926-&&-negative regulation of activin receptor signaling pathway-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0061312-&&-BMP signaling pathway involved in heart development-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0003143-&&-embryonic heart tube morphogenesis|cellular_component-&-1&-GO:0048179-&&-activin receptor complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005025-&&-transforming growth factor beta receptor activity, type I-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0048185-&&-activin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0016361-&&-activin receptor activity, type I-%%-GO:0017046-&&-peptide hormone binding	G:9606:ACVR1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	ACVR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVR1	0.3706061	0.10549645	50	5	FALSE	ACVR1	ACVR1	74.58333333	0	49	0	0.71695289	FALSE	1	ACVR1	144352	0.03860262
792256	taxon:9606	2.5059083	1.23E-04	165958	1902	armadillo repeat containing 6	gene	biological_process-&-1&-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol	G:9606:ARMC6				ARMC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARMC6	0.3990569	0.10612245	50	4	FALSE	ARMC6	ARMC6	135.96	0	50	0	0.74901528	FALSE	0	ARMC6	167404	0.0434688
792257	taxon:9606	2.52134867	1.98E-04	182336	1902	ancient ubiquitous protein 1	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000839-&&-Hrd1p ubiquitin ligase ERAD-L complex-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:AUP1				AUP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AUP1	0.39661314	0.09714286	50	4	FALSE	AUP1	AUP1	135.78	0	50	0	0.74644189	FALSE	0	AUP1	259712	0.0448545
792522	taxon:9606	2.50386009	2.08E-04	181852	1902	calcium/calmodulin dependent protein kinase II gamma	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0006816-&&-calcium ion transport-%%-GO:0014733-&&-regulation of skeletal muscle adaptation-%%-GO:0030154-&&-cell differentiation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0030073-&&-insulin secretion-%%-GO:1901897-&&-regulation of relaxation of cardiac muscle-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004723-&&-calcium-dependent protein serine/threonine phosphatase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding	G:9606:CAMK2G	CAMK2G	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04740-&&-Olfactory transduction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04713-&&-Circadian entrainment-%%-hsa04217-&&-Necroptosis	CAMK2G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK2G	0.39938334	0.05939716	50	4	FALSE	CAMK2G	CAMK2G	123.9166667	0	49	0	0.74935665	FALSE	1	CAMK2G	241328	0.03951746
792531	taxon:9606	2.53489838	9.86E-05	181844	1902	calpain small subunit 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006508-&&-proteolysis-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity	G:9606:CAPNS1				CAPNS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPNS1	0.39449313	0.12244898	50	4	FALSE	CAPNS1	CAPNS1	149.36	0	50	0	0.7441836	FALSE	0	CAPNS1	155826	0.05091778
792792	taxon:9606	2.3882149	2.97E-04	181356	1902	EPH receptor A2	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0030182-&&-neuron differentiation-%%-GO:0060035-&&-notochord cell development-%%-GO:0070309-&&-lens fiber cell morphogenesis-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0006954-&&-inflammatory response-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007155-&&-cell adhesion-%%-GO:1904238-&&-pericyte cell differentiation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0016032-&&-viral process-%%-GO:0032682-&&-negative regulation of chemokine production-%%-GO:0021915-&&-neural tube development-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0048870-&&-cell motility-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0043535-&&-regulation of blood vessel endothelial cell migration-%%-GO:0014028-&&-notochord formation-%%-GO:0048320-&&-axial mesoderm formation-%%-GO:0016477-&&-cell migration-%%-GO:1901491-&&-negative regulation of lymphangiogenesis-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0002043-&&-blood vessel endothelial cell proliferation involved in sprouting angiogenesis-%%-GO:0046849-&&-bone remodeling-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0046058-&&-cAMP metabolic process-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0001501-&&-skeletal system development-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0010591-&&-regulation of lamellipodium assembly-%%-GO:0070848-&&-response to growth factor|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0030027-&&-lamellipodium-%%-GO:0032587-&&-ruffle membrane-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0031256-&&-leading edge membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005003-&&-ephrin receptor activity	G:9606:EPHA2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	EPHA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA2	0.41872279	0.13386525	50	4	FALSE	EPHA2	EPHA2	177.8541667	0	49	0	0.76863085	FALSE	1	EPHA2	351972	0.04606769
793072	taxon:9606	2.48621396	1.31E-04	180805	1902	general transcription factor IIH subunit 1	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006360-&&-transcription from RNA polymerase I promoter-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000439-&&-core TFIIH complex-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:GTF2H1			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair	GTF2H1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2H1	0.402218	0.16312057	50	4	FALSE	GTF2H1	GTF2H1	158.9166667	0	49	0	0.75229767	FALSE	1	GTF2H1	198090	0.04864089
787019	taxon:9606	2.55254451	2.21E-04	180222	1902	integrin subunit beta 2	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050900-&&-leukocyte migration-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0007568-&&-aging-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0031623-&&-receptor internalization-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006909-&&-phagocytosis-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0045123-&&-cellular extravasation-%%-GO:0043113-&&-receptor clustering-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0009986-&&-cell surface-%%-GO:0034687-&&-integrin alphaL-beta2 complex-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043235-&&-receptor complex-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030369-&&-ICAM-3 receptor activity	G:9606:ITGB2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05134-&&-Legionellosis-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05133-&&-Pertussis-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	ITGB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB2	0.39176594	0.08510638	49	4	FALSE	ITGB2	ITGB2	121.9361702	0	48	0	0.74124258	FALSE	1	ITGB2	236012	0.0431028
787196	taxon:9606	2.64928313	1.27E-04	179893	1902	MAGE family member A6	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:MAGEA6				MAGEA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA6	0.3774606	0.02465986	49	4	FALSE	MAGEA6	MAGEA6	82.24489796	0	49	0	0.72511948	FALSE	0	MAGEA6	142620	0.03647629
787327	taxon:9606	2.42145896	3.23E-05	179663	1902	keratin 10	gene	biological_process-&-1&-GO:0030216-&&-keratinocyte differentiation-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005882-&&-intermediate filament-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030280-&&-structural constituent of epidermis	G:9606:KRT10			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway-%%-hsa05150-&&-Staphylococcus aureus infection	KRT10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT10	0.41297417	0.2414966	49	4	FALSE	KRT10	KRT10	263.1020408	0	49	0	0.76309017	FALSE	0	KRT10	126132	0.07221566
787608	taxon:9606	2.47991177	7.95E-05	179110	1902	NFKB inhibitor epsilon	gene	biological_process-&-1&-GO:0042942-&&-D-serine transport-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NFKBIE			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	NFKBIE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIE	0.40324015	0.22756707	49	4	FALSE	NFKBIE	NFKBIE	183.3829787	0	48	0	0.75334804	FALSE	1	NFKBIE	111614	0.05572657
787839	taxon:9606	2.49803057	2.50E-04	178734	1902	mitogen-activated protein kinase 10	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0009416-&&-response to light stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0048666-&&-neuron development-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0010468-&&-regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0004705-&&-JUN kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MAPK10	MAPK10	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04510-&&-Focal adhesion-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK10	0.40031536	0.08325624	49	4	FALSE	MAPK10	MAPK10	140.8510638	0	48	0	0.75032824	FALSE	1	MAPK10	273220	0.04442757
787847	taxon:9606	2.48936505	2.10E-04	178727	1902	mitogen-activated protein kinase kinase 7	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0009408-&&-response to heat-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0007165-&&-signal transduction-%%-GO:0007254-&&-JNK cascade-%%-GO:0009411-&&-response to UV-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0035897-&&-proteolysis in other organism|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:MAP2K7			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa04660-&&-T cell receptor signaling pathway	MAP2K7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K7	0.40170886	0.11378353	49	4	FALSE	MAP2K7	MAP2K7	141.9148936	0	48	0	0.75177249	FALSE	1	MAP2K7	221196	0.04386282
787994	taxon:9606	2.49818812	1.16E-04	178437	1902	pyruvate dehydrogenase (lipoamide) alpha 1	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006086-&&-acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0045254-&&-pyruvate dehydrogenase complex|molecular_function-&-1&-GO:0004739-&&-pyruvate dehydrogenase (acetyl-transferring) activity-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0004738-&&-pyruvate dehydrogenase activity	G:9606:PDHA1			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	PDHA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDHA1	0.40029011	0.13228492	49	4	FALSE	PDHA1	PDHA1	166.4042553	0	48	0	0.75030198	FALSE	1	PDHA1	162796	0.05217037
788090	taxon:9606	2.57838349	7.62E-05	178256	1902	phosphogluconate dehydrogenase	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0019322-&&-pentose biosynthetic process-%%-GO:0019521-&&-D-gluconate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0009051-&&-pentose-phosphate shunt, oxidative branch|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004616-&&-phosphogluconate dehydrogenase (decarboxylating) activity	G:9606:PGD			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00030-&&-Pentose phosphate pathway	PGD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGD	0.3878399	0.11394558	49	4	FALSE	PGD	PGD	132.8163265	0	49	0	0.73693609	FALSE	0	PGD	117400	0.04952026
788206	taxon:9606	2.3878998	7.81E-05	178077	1902	reticulocalbin 2	gene	cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:RCN2				RCN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCN2	0.41877804	0.08758503	49	4	FALSE	RCN2	RCN2	213.3673469	0	49	0	0.76868337	FALSE	0	RCN2	215208	0.05520561
788419	taxon:9606	2.4725067	1.46E-04	177701	1902	mitogen-activated protein kinase kinase 4	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0009611-&&-response to wounding-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0007165-&&-signal transduction-%%-GO:0007254-&&-JNK cascade-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0035897-&&-proteolysis in other organism-%%-GO:2000672-&&-negative regulation of motor neuron apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:0072709-&&-cellular response to sorbitol|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008545-&&-JUN kinase kinase activity-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity	G:9606:MAP2K4			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAP2K4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K4	0.40444784	0.13320999	49	4	FALSE	MAP2K4	MAP2K4	146.7659575	0	48	0	0.75458222	FALSE	1	MAP2K4	185336	0.04387025
788451	taxon:9606	2.41909564	7.31E-05	177650	1902	solute carrier family 3 member 2	gene	biological_process-&-1&-GO:0016049-&&-cell growth-%%-GO:0050900-&&-leukocyte migration-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0006569-&&-tryptophan catabolic process-%%-GO:0060356-&&-leucine import-%%-GO:0015827-&&-tryptophan transport-%%-GO:0006865-&&-amino acid transport-%%-GO:0006816-&&-calcium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0015175-&&-neutral amino acid transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003824-&&-catalytic activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005432-&&-calcium:sodium antiporter activity-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:SLC3A2			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04216-&&-Ferroptosis	SLC3A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC3A2	0.41337762	0.13520408	49	4	FALSE	SLC3A2	SLC3A2	226.3673469	0	49	0	0.76348406	FALSE	0	SLC3A2	182044	0.06195635
788511	taxon:9606	2.6121002	4.40E-04	177530	1902	sorbitol dehydrogenase	gene	biological_process-&-1&-GO:0006970-&&-response to osmotic stress-%%-GO:0051164-&&-L-xylitol metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0042493-&&-response to drug-%%-GO:0009725-&&-response to hormone-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0046370-&&-fructose biosynthetic process-%%-GO:0006062-&&-sorbitol catabolic process-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0019640-&&-glucuronate catabolic process to xylulose 5-phosphate-%%-GO:0046688-&&-response to copper ion-%%-GO:0051160-&&-L-xylitol catabolic process|cellular_component-&-1&-GO:0031514-&&-motile cilium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003939-&&-L-iditol 2-dehydrogenase activity-%%-GO:0046526-&&-D-xylulose reductase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051287-&&-NAD binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0042802-&&-identical protein binding	G:9606:SORD			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways	SORD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORD	0.38283371	0.10083256	49	4	FALSE	SORD	SORD	93.85106383	0	48	0	0.73131663	FALSE	1	SORD	465130	0.03780694
788577	taxon:9606	2.67291634	6.06E-05	177410	1902	TATA-box binding protein associated factor 12	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TAF12			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF12	0.37412319	0.18963922	49	4	FALSE	TAF12	TAF12	141.9787234	0	48	0	0.72118061	FALSE	1	TAF12	113288	0.06583403
789028	taxon:9606	2.48006932	2.32E-04	176336	1902	N(alpha)-acetyltransferase 10, NatA catalytic subunit	gene	biological_process-&-1&-GO:0006323-&&-DNA packaging-%%-GO:0018002-&&-N-terminal peptidyl-glutamic acid acetylation-%%-GO:0017198-&&-N-terminal peptidyl-serine acetylation-%%-GO:0006474-&&-N-terminal protein amino acid acetylation-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0006473-&&-protein acetylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0031415-&&-NatA complex-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0022626-&&-cytosolic ribosome|molecular_function-&-1&-GO:0016407-&&-acetyltransferase activity-%%-GO:1990190-&&-peptide-glutamate-N-acetyltransferase activity-%%-GO:1990189-&&-peptide-serine-N-acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008080-&&-N-acetyltransferase activity-%%-GO:0004596-&&-peptide alpha-N-acetyltransferase activity-%%-GO:0043022-&&-ribosome binding	G:9606:NAA10				NAA10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAA10	0.40321454	0.05272895	49	4	FALSE	NAA10	NAA10	138.4042553	0	48	0	0.75332178	FALSE	1	NAA10	300926	0.04212533
789299	taxon:9606	2.48069954	1.35E-04	175792	1902	QKI, KH domain containing RNA binding	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0042759-&&-long-chain fatty acid biosynthetic process-%%-GO:0051028-&&-mRNA transport-%%-GO:0008380-&&-RNA splicing-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0007286-&&-spermatid development-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:QKI				QKI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QKI	0.4031121	0.19241443	49	4	FALSE	QKI	QKI	155.0851064	0	48	0	0.75321674	FALSE	1	QKI	170650	0.04711893
789358	taxon:9606	2.7015913	4.80E-05	175672	1902	CTD phosphatase subunit 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0070940-&&-dephosphorylation of RNA polymerase II C-terminal domain-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0010458-&&-exit from mitosis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0050434-&&-positive regulation of viral transcription|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000922-&&-spindle pole-%%-GO:0005819-&&-spindle-%%-GO:0051233-&&-spindle midzone-%%-GO:0005813-&&-centrosome-%%-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0016607-&&-nuclear speck-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008420-&&-CTD phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:CTDP1				CTDP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTDP1	0.37015221	0.18027211	49	4	FALSE	CTDP1	CTDP1	91.59183673	0	49	0	0.71640145	FALSE	0	CTDP1	70900	0.0468938
789390	taxon:9606	2.43500867	1.07E-04	175592	1902	mitogen-activated protein kinase-activated protein kinase 2	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032680-&&-regulation of tumor necrosis factor production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048839-&&-inner ear development-%%-GO:0044351-&&-macropinocytosis-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0006954-&&-inflammatory response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0006950-&&-response to stress-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0032675-&&-regulation of interleukin-6 production-%%-GO:0034097-&&-response to cytokine-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0004871-&&-signal transducer activity	G:9606:MAPKAPK2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04370-&&-VEGF signaling pathway	MAPKAPK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPKAPK2	0.41067616	0.11933395	49	4	FALSE	MAPKAPK2	MAPKAPK2	177.5106383	0	48	0	0.76083189	FALSE	1	MAPKAPK2	179358	0.04962159
789394	taxon:9606	2.45107925	8.57E-05	175582	1902	coatomer protein complex subunit beta 2	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:COPB2				COPB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPB2	0.40798354	0.13043478	49	4	FALSE	COPB2	COPB2	204.1914894	0	48	0	0.75815346	FALSE	1	COPB2	160374	0.05856711
789676	taxon:9606	2.44903104	1.02E-04	174918	1902	BAI1 associated protein 2	gene	biological_process-&-1&-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0016358-&&-dendrite development-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0009617-&&-response to bacterium-%%-GO:1905232-&&-cellular response to L-glutamate-%%-GO:0007409-&&-axonogenesis-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0098609-&&-cell-cell adhesion-%%-GO:0007420-&&-brain development-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0030141-&&-secretory granule-%%-GO:0097060-&&-synaptic membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043195-&&-terminal bouton-%%-GO:0005874-&&-microtubule-%%-GO:0060076-&&-excitatory synapse|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0042802-&&-identical protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:BAIAP2			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction	BAIAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAIAP2	0.40832476	0.1239593	49	4	FALSE	BAIAP2	BAIAP2	160.7021277	0	48	0	0.75849483	FALSE	1	BAIAP2	154840	0.04612678
789789	taxon:9606	2.52717819	4.19E-05	174673	1902	TOP1 binding arginine/serine rich protein	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0016925-&&-protein sumoylation-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010842-&&-retina layer formation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0046549-&&-retinal cone cell development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046548-&&-retinal rod cell development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035845-&&-photoreceptor cell outer segment organization|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0016605-&&-PML body-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005814-&&-centriole-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0000922-&&-spindle pole-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003823-&&-antigen binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044547-&&-DNA topoisomerase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:TOPORS				TOPORS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOPORS	0.39569825	0.13506013	49	4	FALSE	TOPORS	TOPORS	173.1702128	0	48	0	0.7454703	FALSE	1	TOPORS	89480	0.05746517
789916	taxon:9606	2.6037498	2.40E-04	174371	1902	serine peptidase inhibitor, Kunitz type 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0071711-&&-basement membrane organization-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0060672-&&-epithelial cell morphogenesis involved in placental branching-%%-GO:0001843-&&-neural tube closure-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:2000146-&&-negative regulation of cell motility|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity	G:9606:SPINT2				SPINT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPINT2	0.38406148	0.01360544	49	4	FALSE	SPINT2	SPINT2	81.83673469	0	49	0	0.73270837	FALSE	0	SPINT2	214462	0.0326777
789967	taxon:9606	2.53190484	4.12E-05	174223	1902	serine/threonine kinase 38	gene	biological_process-&-1&-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:STK38				STK38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK38	0.39495955	0.14153562	49	4	FALSE	STK38	STK38	224.212766	0	48	0	0.74468253	FALSE	1	STK38	119398	0.07517445
790069	taxon:9606	2.55207184	3.13E-05	173958	1902	PC4 and SFRS1 interacting protein 1	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0051169-&&-nuclear transport-%%-GO:0000395-&&-mRNA 5'-splice site recognition-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0075713-&&-establishment of integrated proviral latency-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009408-&&-response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0097100-&&-supercoiled DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PSIP1				PSIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSIP1	0.3918385	0.1547619	49	4	FALSE	PSIP1	PSIP1	185.1428571	0	49	0	0.74132136	FALSE	0	PSIP1	85420	0.06477343
790165	taxon:9606	2.53285017	1.24E-04	173731	1902	spen family transcriptional repressor	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SPEN				SPEN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPEN	0.39481214	0.10034014	49	4	FALSE	SPEN	SPEN	157.8979592	0	49	0	0.74452497	FALSE	0	SPEN	192798	0.05317678
790281	taxon:9606	2.60627068	1.75E-04	173449	1902	glutamate receptor interacting protein 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0016358-&&-dendrite development-%%-GO:0008104-&&-protein localization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0043005-&&-neuron projection-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0035259-&&-glucocorticoid receptor binding	G:9606:GRIP1				GRIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIP1	0.38369	0.20351526	49	4	FALSE	GRIP1	GRIP1	190.2340426	0	48	0	0.73228822	FALSE	1	GRIP1	238002	0.07525533
790625	taxon:9606	2.60926422	1.12E-04	171720	1902	angiomotin like 2	gene	biological_process-&-1&-GO:0016055-&&-Wnt signaling pathway-%%-GO:0035329-&&-hippo signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0055037-&&-recycling endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:AMOTL2			KEGG-&-1&-hsa04530-&&-Tight junction	AMOTL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMOTL2	0.3832498	0.08048104	49	4	FALSE	AMOTL2	AMOTL2	94.46808511	0	48	0	0.7317893	FALSE	1	AMOTL2	132690	0.03766085
790747	taxon:9606	2.75831101	1.59E-04	171336	1902	coiled-coil-helix-coiled-coil-helix domain containing 2	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1900037-&&-regulation of cellular response to hypoxia-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:CHCHD2				CHCHD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHCHD2	0.3625407	0.07770583	49	4	FALSE	CHCHD2	CHCHD2	63.61702128	0	48	0	0.70694816	FALSE	1	CHCHD2	183014	0.03947194
790851	taxon:9606	2.45738144	1.91E-04	170893	1902	N-acetylneuraminate synthase	gene	biological_process-&-1&-GO:0009103-&&-lipopolysaccharide biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008781-&&-N-acylneuraminate cytidylyltransferase activity-%%-GO:0047444-&&-N-acylneuraminate-9-phosphate synthase activity-%%-GO:0050462-&&-N-acetylneuraminate synthase activity	G:9606:NANS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	NANS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NANS	0.40693723	0.0994898	49	4	FALSE	NANS	NANS	147.755102	0	49	0	0.75710309	FALSE	0	NANS	234370	0.04299082
790896	taxon:9606	2.51362849	5.57E-05	170744	1902	denticleless E3 ubiquitin protein ligase homolog	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0009411-&&-response to UV-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031465-&&-Cul4B-RING E3 ubiquitin ligase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:DTL				DTL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTL	0.39783126	0.16411565	49	4	FALSE	DTL	DTL	178.4693878	0	49	0	0.74772859	FALSE	0	DTL	109164	0.05776917
790956	taxon:9606	2.47518513	8.81E-05	170604	1902	serine/threonine kinase 26	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0030033-&&-microvillus assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1903205-&&-regulation of hydrogen peroxide-induced cell death-%%-GO:0045595-&&-regulation of cell differentiation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity	G:9606:STK26				STK26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK26	0.40401018	0.14153562	49	4	FALSE	STK26	STK26	137.3829787	0	48	0	0.75413581	FALSE	1	STK26	144336	0.04145467
790975	taxon:9606	2.4495037	1.13E-04	170537	1902	ring finger protein 31	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0023035-&&-CD40 signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0097039-&&-protein linear polyubiquitination-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0071797-&&-LUBAC complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:RNF31			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	RNF31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF31	0.40824596	0.16466235	49	4	FALSE	RNF31	RNF31	163	0	48	0	0.75841605	FALSE	1	RNF31	188302	0.04695694
791119	taxon:9606	2.3666299	7.58E-05	169989	1902	leucine rich repeat containing 59	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031090-&&-organelle membrane-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:LRRC59				LRRC59	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRC59	0.42254177	0.12159864	49	4	FALSE	LRRC59	LRRC59	280.5306122	0	49	0	0.77222835	FALSE	0	LRRC59	201992	0.07030047
791677	taxon:9606	2.42319206	7.65E-05	167469	1902	WD repeat domain 82	gene	biological_process-&-1&-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0000785-&&-chromatin-%%-GO:0035097-&&-histone methyltransferase complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:WDR82			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	WDR82	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR82	0.4126788	0.18622449	49	4	FALSE	WDR82	WDR82	210.755102	0	49	0	0.76280132	FALSE	0	WDR82	161762	0.05765655
791745	taxon:9606	2.64723491	4.51E-05	167081	1902	L3MBTL2 polycomb repressive complex 1 subunit	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0035064-&&-methylated histone binding	G:9606:L3MBTL2				L3MBTL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-L3MBTL2	0.37775265	0.29846939	49	4	FALSE	L3MBTL2	L3MBTL2	214.0816327	0	49	0	0.72546085	FALSE	0	L3MBTL2	124080	0.09301191
791844	taxon:9606	2.47865133	1.16E-04	182984	1902	alanyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006419-&&-alanyl-tRNA aminoacylation-%%-GO:0021680-&&-cerebellar Purkinje cell layer development-%%-GO:0006400-&&-tRNA modification-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001942-&&-hair follicle development-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0043200-&&-response to amino acid-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0008033-&&-tRNA processing|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004813-&&-alanine-tRNA ligase activity-%%-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0000049-&&-tRNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0016597-&&-amino acid binding	G:9606:AARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	AARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AARS	0.40344521	0.16326531	49	4	FALSE	AARS	AARS	172	0	49	0	0.75355811	FALSE	0	AARS	174250	0.05210884
791898	taxon:9606	2.35922483	7.84E-05	182915	1902	adaptor related protein complex 2 alpha 2 subunit	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030667-&&-secretory granule membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0003674-&&-molecular_function	G:9606:AP2A2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2A2	0.42386804	0.24051804	49	4	FALSE	AP2A2	AP2A2	247.0638298	0	48	0	0.77346253	FALSE	1	AP2A2	158026	0.06110377
792074	taxon:9606	2.42839137	8.53E-05	182657	1902	CDC like kinase 3	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0016020-&&-membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0042802-&&-identical protein binding	G:9606:CLK3				CLK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLK3	0.41179524	0.14616096	49	4	FALSE	CLK3	CLK3	186.787234	0	48	0	0.76193477	FALSE	1	CLK3	150436	0.05165828
792682	taxon:9606	2.66692926	1.25E-04	181571	1902	DCC netrin 1 receptor	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0033564-&&-anterior/posterior axon guidance-%%-GO:0001764-&&-neuron migration-%%-GO:0038007-&&-netrin-activated signaling pathway-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0021965-&&-spinal cord ventral commissure morphogenesis-%%-GO:0048671-&&-negative regulation of collateral sprouting-%%-GO:0007409-&&-axonogenesis-%%-GO:0033563-&&-dorsal/ventral axon guidance-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007411-&&-axon guidance-%%-GO:2000171-&&-negative regulation of dendrite development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005042-&&-netrin receptor activity-%%-GO:0005515-&&-protein binding	G:9606:DCC			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer	DCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCC	0.37496308	0.07823129	49	4	FALSE	DCC	DCC	101.0816327	0	49	0	0.72217846	FALSE	0	DCC	145244	0.04759334
787091	taxon:9606	2.64896802	5.63E-05	163691	1902	centrosomal protein 120	gene	biological_process-&-1&-GO:0010825-&&-positive regulation of centrosome duplication-%%-GO:0022027-&&-interkinetic nuclear migration-%%-GO:0030953-&&-astral microtubule organization-%%-GO:0051297-&&-centrosome organization-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0022008-&&-neurogenesis-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0005813-&&-centrosome-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:CEP120				CEP120	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP120	0.3775055	0.2287234	48	4	FALSE	CEP120	CEP120	90.89583333	0	48	0	0.725172	FALSE	0	CEP120	82176	0.04009382
787264	taxon:9606	2.50921695	9.47E-05	179777	1902	JunD proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0009416-&&-response to light stimulus-%%-GO:0010941-&&-regulation of cell death-%%-GO:0034097-&&-response to cytokine-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0002076-&&-osteoblast development-%%-GO:0051591-&&-response to cAMP-%%-GO:0007568-&&-aging-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007623-&&-circadian rhythm-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0009314-&&-response to radiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043434-&&-response to peptide hormone|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:JUND			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04380-&&-Osteoclast differentiation	JUND	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JUND	0.3985307	0.19414894	48	4	FALSE	JUND	JUND	156.5833333	0	48	0	0.74846384	FALSE	0	JUND	148622	0.05026359
787317	taxon:9606	2.43563888	2.87E-05	179672	1902	keratin 2	gene	biological_process-&-1&-GO:0051546-&&-keratinocyte migration-%%-GO:0008544-&&-epidermis development-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0031424-&&-keratinization-%%-GO:0032980-&&-keratinocyte activation-%%-GO:0070268-&&-cornification-%%-GO:0003334-&&-keratinocyte development-%%-GO:0045109-&&-intermediate filament organization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045095-&&-keratin filament-%%-GO:0005882-&&-intermediate filament-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding	G:9606:KRT2				KRT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT2	0.41056989	0.24468085	48	4	FALSE	KRT2	KRT2	264.0625	0	48	0	0.76072685	FALSE	0	KRT2	111850	0.074321
787438	taxon:9606	2.5936663	3.92E-04	179439	1902	galectin 8	gene	biological_process-&-1&-GO:0098792-&&-xenophagy-%%-GO:0098586-&&-cellular response to virus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005515-&&-protein binding	G:9606:LGALS8				LGALS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS8	0.38555461	0.02216312	48	4	FALSE	LGALS8	LGALS8	96	0	48	0	0.73438895	FALSE	0	LGALS8	367064	0.03742647
787442	taxon:9606	2.4808571	5.21E-05	179424	1902	malate dehydrogenase 2	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0006108-&&-malate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0006734-&&-NADH metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046554-&&-malate dehydrogenase (NADP+) activity-%%-GO:0030060-&&-L-malate dehydrogenase activity-%%-GO:0043621-&&-protein self-association-%%-GO:0003723-&&-RNA binding	G:9606:MDH2			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	MDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDH2	0.4030865	0.16231884	48	4	FALSE	MDH2	MDH2	228.0869565	0	47	0	0.75319048	FALSE	1	MDH2	122492	0.06940512
787642	taxon:9606	2.49361903	1.44E-04	179025	1902	nardilysin convertase	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0016477-&&-cell migration-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0008283-&&-cell proliferation-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0052548-&&-regulation of endopeptidase activity|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0048408-&&-epidermal growth factor binding	G:9606:NRDC				NRDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRDC	0.40102357	0.08792271	48	4	FALSE	NRDC	NRDC	139.4565217	0	47	0	0.75106349	FALSE	1	NRDC	174416	0.04337001
787798	taxon:9606	2.48983772	1.55E-04	178768	1902	protein kinase cAMP-activated catalytic subunit beta	gene	biological_process-&-1&-GO:0051447-&&-negative regulation of meiotic cell cycle-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation-%%-GO:1901621-&&-negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0001843-&&-neural tube closure-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0097338-&&-response to clozapine-%%-GO:0070613-&&-regulation of protein processing-%%-GO:0034199-&&-activation of protein kinase A activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0097546-&&-ciliary base-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity	G:9606:PRKACB			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04740-&&-Olfactory transduction-%%-hsa04530-&&-Tight junction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04976-&&-Bile secretion-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05020-&&-Prion diseases-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05030-&&-Cocaine addiction-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04970-&&-Salivary secretion	PRKACB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKACB	0.4016326	0.10638298	48	4	FALSE	PRKACB	PRKACB	127.0833333	0	48	0	0.75169371	FALSE	0	PRKACB	189280	0.03925811
787806	taxon:9606	2.54671498	1.28E-04	178760	1902	protein kinase cAMP-dependent type II regulatory subunit alpha	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0097546-&&-ciliary base-%%-GO:0005813-&&-centrosome-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0016020-&&-membrane-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PRKAR2A			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	PRKAR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAR2A	0.39266271	0.08309179	48	4	FALSE	PRKAR2A	PRKAR2A	122.0217391	0	47	0	0.74221417	FALSE	1	PRKAR2A	150086	0.04250803
787931	taxon:9606	2.52969907	6.25E-05	178567	1902	origin recognition complex subunit 4	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006260-&&-DNA replication|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000808-&&-origin recognition complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003688-&&-DNA replication origin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0005515-&&-protein binding	G:9606:ORC4	ORC4	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle	ORC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORC4	0.39530394	0.2393617	48	4	FALSE	ORC4	ORC4	196.3125	0	48	0	0.74505015	FALSE	0	ORC4	118570	0.06547421
788084	taxon:9606	2.59083031	6.73E-05	178265	1902	mitochondrial ribosomal protein L12	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0006390-&&-transcription from mitochondrial promoter|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPL12			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL12	0.38597665	0.20193237	48	4	FALSE	MRPL12	MRPL12	163.7608696	0	47	0	0.73486161	FALSE	1	MRPL12	102330	0.06249481
788135	taxon:9606	2.54687254	3.46E-04	178179	1902	peroxisomal biogenesis factor 19	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006625-&&-protein targeting to peroxisome-%%-GO:0072321-&&-chaperone-mediated protein transport-%%-GO:0072663-&&-establishment of protein localization to peroxisome-%%-GO:0050821-&&-protein stabilization-%%-GO:0007031-&&-peroxisome organization-%%-GO:0045046-&&-protein import into peroxisome membrane-%%-GO:1900131-&&-negative regulation of lipid binding-%%-GO:0016559-&&-peroxisome fission-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0031526-&&-brush border membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0036105-&&-peroxisome membrane class-1 targeting sequence binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0051117-&&-ATPase binding	G:9606:PEX19			KEGG-&-1&-hsa04146-&&-Peroxisome	PEX19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEX19	0.39263842	0.03188406	48	4	FALSE	PEX19	PEX19	105.5869565	0	47	0	0.74218791	FALSE	1	PEX19	318660	0.03668715
788201	taxon:9606	2.58972743	2.07E-04	178095	1902	RB binding protein 8, endonuclease	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0010792-&&-DNA double-strand break processing involved in repair via single-strand annealing-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0051301-&&-cell division-%%-GO:0000075-&&-cell cycle checkpoint-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0032355-&&-response to estradiol-%%-GO:0000732-&&-strand displacement-%%-GO:0001835-&&-blastocyst hatching-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006281-&&-DNA repair-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000014-&&-single-stranded DNA endodeoxyribonuclease activity	G:9606:RBBP8			KEGG-&-1&-hsa03440-&&-Homologous recombination	RBBP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBBP8	0.38614102	0.09758454	48	4	FALSE	RBBP8	RBBP8	119.2826087	0	47	0	0.73504543	FALSE	1	RBBP8	224848	0.04567885
788219	taxon:9606	2.59807783	6.03E-05	178059	1902	double PHD fingers 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:DPF2				DPF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPF2	0.38489994	0.18794326	48	4	FALSE	DPF2	DPF2	149.5833333	0	48	0	0.73365369	FALSE	0	DPF2	110288	0.0580438
788332	taxon:9606	2.44918859	1.19E-04	177871	1902	ataxin 2	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0050658-&&-RNA transport-%%-GO:0034063-&&-stress granule assembly-%%-GO:0006417-&&-regulation of translation-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0010603-&&-regulation of cytoplasmic mRNA processing body assembly|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:ATXN2				ATXN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN2	0.40829849	0.13829787	48	4	FALSE	ATXN2	ATXN2	191.7708333	0	48	0	0.75846857	FALSE	0	ATXN2	183030	0.05522334
788537	taxon:9606	2.68158185	5.58E-05	177486	1902	sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)	gene	biological_process-&-1&-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004757-&&-sepiapterin reductase activity-%%-GO:0050661-&&-NADP binding-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity	G:9606:SPR			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	SPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPR	0.37291422	0.1294686	48	4	FALSE	SPR	SPR	95.10869565	0	47	0	0.71973636	FALSE	1	SPR	85778	0.04630551
788878	taxon:9606	2.55285962	5.73E-05	176707	1902	eukaryotic translation initiation factor 4H	gene	biological_process-&-1&-GO:0019953-&&-sexual reproduction-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0097010-&&-eukaryotic translation initiation factor 4F complex assembly-%%-GO:0006413-&&-translational initiation-%%-GO:0016032-&&-viral process-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0048589-&&-developmental growth|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005844-&&-polysome-%%-GO:0016020-&&-membrane-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0033592-&&-RNA strand annealing activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0004386-&&-helicase activity-%%-GO:0034057-&&-RNA strand-exchange activity-%%-GO:0043024-&&-ribosomal small subunit binding	G:9606:EIF4H				EIF4H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4H	0.39171758	0.14095745	48	4	FALSE	EIF4H	EIF4H	165.375	0	48	0	0.74119006	FALSE	0	EIF4H	100758	0.05801901
788947	taxon:9606	2.55112652	2.69E-05	176548	1902	HIRA interacting protein 3	gene	biological_process-&-1&-GO:0006333-&&-chromatin assembly or disassembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:HIRIP3				HIRIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIRIP3	0.3919837	0.23315603	48	4	FALSE	HIRIP3	HIRIP3	186.9583333	0	48	0	0.74147891	FALSE	0	HIRIP3	77646	0.06561513
789015	taxon:9606	2.49346148	8.21E-05	176377	1902	symplekin	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0007155-&&-cell adhesion-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0097165-&&-nuclear stress granule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SYMPK			KEGG-&-1&-hsa04530-&&-Tight junction-%%-hsa03015-&&-mRNA surveillance pathway	SYMPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYMPK	0.40104891	0.11347518	48	4	FALSE	SYMPK	SYMPK	180.2291667	0	48	0	0.75108975	FALSE	0	SYMPK	173428	0.05617072
789030	taxon:9606	2.47392469	6.91E-05	176325	1902	AT-rich interaction domain 1A	gene	biological_process-&-1&-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0003408-&&-optic cup formation involved in camera-type eye development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006344-&&-maintenance of chromatin silencing-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0003205-&&-cardiac chamber development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:1901998-&&-toxin transport-%%-GO:0042766-&&-nucleosome mobilization-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0001843-&&-neural tube closure-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0030900-&&-forebrain development-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0007566-&&-embryo implantation-%%-GO:0042921-&&-glucocorticoid receptor signaling pathway-%%-GO:0001704-&&-formation of primary germ layer-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006338-&&-chromatin remodeling|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071564-&&-npBAF complex-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding	G:9606:ARID1A	ARID1A	TRUE	KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	ARID1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARID1A	0.40421602	0.25886525	48	4	FALSE	ARID1A	ARID1A	200.3541667	0	48	0	0.75434589	FALSE	0	ARID1A	144710	0.05987248
789229	taxon:9606	2.69733732	1.28E-04	175957	1902	serine/threonine kinase 16	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:STK16				STK16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK16	0.37073598	0.08502415	48	4	FALSE	STK16	STK16	82.5	0	47	0	0.71711045	FALSE	1	STK16	154486	0.04220801
789461	taxon:9606	2.52544509	1.60E-04	175418	1902	SEC22 homolog B, vesicle trafficking protein (gene/pseudogene)	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0015031-&&-protein transport-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0033043-&&-regulation of organelle organization-%%-GO:0048280-&&-vesicle fusion with Golgi apparatus-%%-GO:0006887-&&-exocytosis-%%-GO:1990668-&&-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0031201-&&-SNARE complex-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0019905-&&-syntaxin binding	G:9606:SEC22B			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04145-&&-Phagosome-%%-hsa05134-&&-Legionellosis	SEC22B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC22B	0.3959698	0.1072695	48	4	FALSE	SEC22B	SEC22B	179.5833333	0	48	0	0.74575915	FALSE	0	SEC22B	261534	0.05946957
789501	taxon:9606	2.50338743	1.17E-04	175328	1902	scaffold attachment factor B2	gene	biological_process-&-1&-GO:0050684-&&-regulation of mRNA processing-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0060008-&&-Sertoli cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SAFB2				SAFB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAFB2	0.39945875	0.15652174	48	4	FALSE	SAFB2	SAFB2	209.2826087	0	47	0	0.74943543	FALSE	1	SAFB2	189674	0.06650999
789599	taxon:9606	2.48400819	3.87E-05	175092	1902	pumilio RNA binding family member 3	gene	biological_process-&-1&-GO:0010835-&&-regulation of protein ADP-ribosylation-%%-GO:0006417-&&-regulation of translation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:PUM3				PUM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUM3	0.40257516	0.44060284	48	4	FALSE	PUM3	PUM3	208.6041667	0	48	0	0.7526653	FALSE	0	PUM3	73890	0.06359248
789683	taxon:9606	2.55853159	1.23E-04	174902	1902	transcriptional adaptor 3	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0031063-&&-regulation of histone deacetylation-%%-GO:0090043-&&-regulation of tubulin deacetylation-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0030914-&&-STAGA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005634-&&-nucleus-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TADA3			KEGG-&-1&-hsa05165-&&-Human papillomavirus infection	TADA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TADA3	0.39084919	0.16578014	48	4	FALSE	TADA3	TADA3	132.6041667	0	48	0	0.74024474	FALSE	0	TADA3	160760	0.0470934
789714	taxon:9606	2.48999527	3.36E-04	174841	1902	peroxiredoxin 4	gene	biological_process-&-1&-GO:0019471-&&-4-hydroxyproline metabolic process-%%-GO:0022417-&&-protein maturation by protein folding-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007283-&&-spermatogenesis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:2000255-&&-negative regulation of male germ cell proliferation-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0008584-&&-male gonad development-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005790-&&-smooth endoplasmic reticulum|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PRDX4	PRDX4	TRUE		PRDX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX4	0.40160719	0.10338164	48	4	FALSE	PRDX4	PRDX4	201.8043478	0	47	0	0.75166745	FALSE	1	PRDX4	417746	0.06263085
789783	taxon:9606	2.42413739	6.44E-05	174687	1902	protein arginine methyltransferase 3	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PRMT3				PRMT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT3	0.41251787	0.20656028	48	4	FALSE	PRMT3	PRMT3	232.0833333	0	48	0	0.76264377	FALSE	0	PRMT3	138790	0.06358477
789804	taxon:9606	2.48857728	9.71E-05	174630	1902	signal transducing adaptor molecule 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0061024-&&-membrane organization-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016197-&&-endosomal transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0033565-&&-ESCRT-0 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:STAM2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04630-&&-JAK-STAT signaling pathway	STAM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAM2	0.40183602	0.1001773	48	4	FALSE	STAM2	STAM2	143.5	0	48	0	0.75190379	FALSE	0	STAM2	165550	0.04446209
789920	taxon:9606	2.58027415	5.09E-05	174361	1902	CCCTC-binding factor	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0070602-&&-regulation of centromeric sister chromatid cohesion-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006306-&&-DNA methylation-%%-GO:0040030-&&-regulation of molecular function, epigenetic-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031060-&&-regulation of histone methylation-%%-GO:0035065-&&-regulation of histone acetylation-%%-GO:0016584-&&-nucleosome positioning-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043035-&&-chromatin insulator sequence binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:CTCF				CTCF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTCF	0.38755572	0.11347518	48	5	FALSE	CTCF	CTCF	167.9375	0	48	0	0.73662098	FALSE	0	CTCF	98164	0.06238387
790355	taxon:9606	2.44083819	8.47E-05	173237	1902	microtubule-actin crosslinking factor 1	gene	biological_process-&-1&-GO:0042060-&&-wound healing-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0003779-&&-actin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0003723-&&-RNA binding	G:9606:MACF1				MACF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MACF1	0.40969533	0.09574468	48	4	FALSE	MACF1	MACF1	216.8125	0	48	0	0.7598603	FALSE	0	MACF1	164480	0.06141407
790395	taxon:9606	2.47234914	1.49E-04	173126	1902	HSPA (Hsp70) binding protein 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|molecular_function-&-1&-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:HSPBP1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	HSPBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPBP1	0.40447362	0.13120567	48	4	FALSE	HSPBP1	HSPBP1	145.8333333	0	48	0	0.75460848	FALSE	0	HSPBP1	215652	0.04365823
790627	taxon:9606	2.48274775	9.47E-05	171712	1902	anaphase promoting complex subunit 7	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding	G:9606:ANAPC7			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC7	0.40277954	0.23478261	48	4	FALSE	ANAPC7	ANAPC7	174.7826087	0	47	0	0.75287537	FALSE	1	ANAPC7	151958	0.05330663
790714	taxon:9606	2.41988341	1.66E-04	171401	1902	epsin 1	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006897-&&-endocytosis-%%-GO:0007565-&&-female pregnancy-%%-GO:0048568-&&-embryonic organ development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:EPN1			KEGG-&-1&-hsa04144-&&-Endocytosis	EPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPN1	0.41324305	0.14007092	48	4	FALSE	EPN1	EPN1	191	0	48	0	0.76335277	FALSE	0	EPN1	244978	0.05219154
791010	taxon:9606	2.58641878	4.65E-05	170393	1902	ring finger protein 111	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0007389-&&-pattern specification process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0032184-&&-SUMO polymer binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF111				RNF111	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF111	0.38663499	0.13623188	48	4	FALSE	RNF111	RNF111	132.4782609	0	47	0	0.73559687	FALSE	1	RNF111	87138	0.05024906
791097	taxon:9606	2.42524027	6.92E-05	170057	1902	protein phosphatase 6 regulatory subunit 3	gene	biological_process-&-1&-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:PPP6R3				PPP6R3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP6R3	0.41233028	0.12234043	48	4	FALSE	PPP6R3	PPP6R3	192.7916667	0	48	0	0.76245995	FALSE	0	PPP6R3	139546	0.05281698
791253	taxon:9606	2.44698283	1.16E-04	169525	1902	BRCA2 and CDKN1A interacting protein	gene	biological_process-&-1&-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0061101-&&-neuroendocrine cell differentiation-%%-GO:0007049-&&-cell cycle-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019908-&&-nuclear cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019207-&&-kinase regulator activity	G:9606:BCCIP				BCCIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCCIP	0.40866654	0.12411348	48	4	FALSE	BCCIP	BCCIP	179.1041667	0	48	0	0.7588362	FALSE	0	BCCIP	185614	0.05118401
791301	taxon:9606	2.55301717	1.06E-04	169288	1902	potassium channel modulatory factor 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity	G:9606:KCMF1				KCMF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCMF1	0.39169341	0.13236715	48	4	FALSE	KCMF1	KCMF1	138.0652174	0	47	0	0.7411638	FALSE	1	KCMF1	146044	0.0484568
791328	taxon:9606	2.65527021	1.74E-04	169148	1902	golgi associated PDZ and coiled-coil motif containing	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0043004-&&-cytoplasmic sequestering of CFTR protein-%%-GO:0045176-&&-apical protein localization-%%-GO:0015031-&&-protein transport-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0044325-&&-ion channel binding	G:9606:GOPC				GOPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOPC	0.37660951	0.02995169	48	4	FALSE	GOPC	GOPC	77.32608696	0	47	0	0.72412163	FALSE	1	GOPC	161744	0.03540487
791469	taxon:9606	2.5107925	1.90E-04	168514	1902	derlin 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0036503-&&-ERAD pathway-%%-GO:0031648-&&-protein destabilization-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0019060-&&-intracellular transport of viral protein in host cell-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005770-&&-late endosome-%%-GO:0005769-&&-early endosome-%%-GO:0036502-&&-Derlin-1-VIMP complex-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043657-&&-host cell-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004872-&&-receptor activity-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0051117-&&-ATPase binding	G:9606:DERL1			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DERL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DERL1	0.39828062	0.11400966	48	4	FALSE	DERL1	DERL1	120.1521739	0	47	0	0.74820125	FALSE	1	DERL1	206386	0.03884349
791707	taxon:9606	2.70553017	8.58E-05	167286	1902	RNA binding motif protein 48	gene	cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBM48				RBM48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM48	0.36961332	0.03478261	48	4	FALSE	RBM48	RBM48	77.60869565	0	47	0	0.71574497	FALSE	1	RBM48	107668	0.04033211
791930	taxon:9606	2.54671498	1.35E-04	182862	1902	aldehyde dehydrogenase 3 family member A2	gene	biological_process-&-1&-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0033306-&&-phytol metabolic process-%%-GO:0008544-&&-epidermis development-%%-GO:0007417-&&-central nervous system development-%%-GO:0001561-&&-fatty acid alpha-oxidation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007422-&&-peripheral nervous system development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity-%%-GO:0046577-&&-long-chain-alcohol oxidase activity-%%-GO:0004030-&&-aldehyde dehydrogenase [NAD(P)+] activity	G:9606:ALDH3A2			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00340-&&-Histidine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	ALDH3A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH3A2	0.39266271	0.04432624	48	4	FALSE	ALDH3A2	ALDH3A2	122.6666667	0	48	0	0.74221417	FALSE	0	ALDH3A2	169558	0.04267672
791986	taxon:9606	2.59020009	9.11E-04	182768	1902	apolipoprotein B	gene	biological_process-&-1&-GO:0009743-&&-response to carbohydrate-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0033344-&&-cholesterol efflux-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0010269-&&-response to selenium ion-%%-GO:0045540-&&-regulation of cholesterol biosynthetic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0009566-&&-fertilization-%%-GO:0034379-&&-very-low-density lipoprotein particle assembly-%%-GO:0042159-&&-lipoprotein catabolic process-%%-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007399-&&-nervous system development-%%-GO:0006642-&&-triglyceride mobilization-%%-GO:0030301-&&-cholesterol transport-%%-GO:0032355-&&-response to estradiol-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0071379-&&-cellular response to prostaglandin stimulus-%%-GO:0009791-&&-post-embryonic development-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0009615-&&-response to virus-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0061024-&&-membrane organization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0034360-&&-chylomicron remnant-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0034362-&&-low-density lipoprotein particle-%%-GO:0042627-&&-chylomicron-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0034359-&&-mature chylomicron-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0010008-&&-endosome membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0031904-&&-endosome lumen-%%-GO:0034363-&&-intermediate-density lipoprotein particle-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035473-&&-lipase binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0017127-&&-cholesterol transporter activity-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding	G:9606:APOB	APOB	TRUE	KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa04977-&&-Vitamin digestion and absorption	APOB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOB	0.38607056	0.04830918	48	4	FALSE	APOB	APOB	98.08695652	0	47	0	0.73496665	FALSE	1	APOB	1030276	0.03792317
792073	taxon:9606	2.46904049	7.62E-05	182662	1902	chloride intracellular channel 1	gene	biological_process-&-1&-GO:0006821-&&-chloride transport-%%-GO:0070527-&&-platelet aggregation-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0007165-&&-signal transduction-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:1902476-&&-chloride transmembrane transport|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0034707-&&-chloride channel complex-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005254-&&-chloride channel activity	G:9606:CLIC1				CLIC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLIC1	0.40501563	0.08792271	48	4	FALSE	CLIC1	CLIC1	214.9565217	0	47	0	0.75515992	FALSE	1	CLIC1	140354	0.06419735
792273	taxon:9606	2.33874271	2.07E-04	182311	1902	cell division cycle 25A	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0009314-&&-response to radiation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0034644-&&-cellular response to UV|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:CDC25A			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04218-&&-Cellular senescence-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC25A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC25A	0.42758017	0.15159574	48	4	FALSE	CDC25A	CDC25A	229.8333333	0	48	0	0.77687621	FALSE	0	CDC25A	257430	0.05514882
792287	taxon:9606	2.46573184	1.55E-04	182286	1902	cyclin dependent kinase 3	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045023-&&-G0 to G1 transition-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008283-&&-cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051301-&&-cell division-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0010033-&&-response to organic substance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK3				CDK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK3	0.40555911	0.1884058	48	4	FALSE	CDK3	CDK3	171.826087	0	47	0	0.75571136	FALSE	1	CDK3	182348	0.05086841
792576	taxon:9606	2.47691823	8.99E-05	181785	1902	cyclin H	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:1901409-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0070985-&&-TFIIK complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005675-&&-holo TFIIH complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0005515-&&-protein binding	G:9606:CCNH			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	CCNH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNH	0.4037275	0.15957447	48	4	FALSE	CCNH	CCNH	170.1458333	0	48	0	0.75384696	FALSE	0	CCNH	146334	0.05107608
792770	taxon:9606	2.65590043	6.83E-05	181403	1902	docking protein 1	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK1			KEGG-&-1&-hsa05162-&&-Measles	DOK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK1	0.37652014	0.2763285	48	4	FALSE	DOK1	DOK1	124.5434783	0	47	0	0.7240166	FALSE	1	DOK1	84782	0.05683939
792809	taxon:9606	2.45895699	5.00E-05	181333	1902	E74 like ETS transcription factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008544-&&-epidermis development-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0060056-&&-mammary gland involution-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001824-&&-blastocyst development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ELF3				ELF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELF3	0.40667649	0.09855072	48	4	FALSE	ELF3	ELF3	180.9565217	0	47	0	0.7568405	FALSE	1	ELF3	118964	0.05287862
793019	taxon:9606	2.54955097	1.43E-04	180887	1902	G protein pathway suppressor 2	gene	biological_process-&-1&-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:GPS2			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	GPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPS2	0.39222593	0.12173913	48	4	FALSE	GPS2	GPS2	132.6086957	0	47	0	0.74174151	FALSE	1	GPS2	162998	0.04602469
793211	taxon:9606	2.59918072	9.28E-05	180523	1902	heat shock transcription factor 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	G:9606:HSF2				HSF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSF2	0.38473662	0.05762411	48	4	FALSE	HSF2	HSF2	102.8125	0	48	0	0.73346988	FALSE	0	HSF2	121612	0.03973093
787134	taxon:9606	2.48936505	1.74E-05	180005	1902	inhibitor of growth family member 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000772-&&-regulation of cellular senescence-%%-GO:0007286-&&-spermatid development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007141-&&-male meiosis I-%%-GO:0007165-&&-signal transduction-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0048133-&&-male germ-line stem cell asymmetric division-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0040008-&&-regulation of growth-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0005634-&&-nucleus-%%-GO:0016602-&&-CCAAT-binding factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:ING2				ING2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ING2	0.40170886	0.32377428	47	4	FALSE	ING2	ING2	229.6808511	0	47	0	0.75177249	FALSE	0	ING2	63760	0.07088915
787168	taxon:9606	2.66787459	1.17E-04	179938	1902	lymphotoxin beta receptor	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0016032-&&-viral process-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:LTBR			KEGG-&-1&-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04066-&&-HIF-1 signaling pathway	LTBR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTBR	0.37483021	0.06565657	47	4	FALSE	LTBR	LTBR	84.42222222	0	46	0	0.7220209	FALSE	1	LTBR	123128	0.03979597
787207	taxon:9606	2.53221995	1.06E-04	179864	1902	microtubule affinity regulating kinase 3	gene	biological_process-&-1&-GO:0030010-&&-establishment of cell polarity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MARK3				MARK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARK3	0.3949104	0.11818182	47	4	FALSE	MARK3	MARK3	152.8666667	0	46	0	0.74463001	FALSE	1	MARK3	140700	0.05139544
787294	taxon:9606	2.53757681	1.16E-04	179717	1902	kinesin family member 2A	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007399-&&-nervous system development-%%-GO:0051301-&&-cell division-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0030154-&&-cell differentiation-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0016020-&&-membrane-%%-GO:0097228-&&-sperm principal piece-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005871-&&-kinesin complex-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0003774-&&-motor activity	G:9606:KIF2A				KIF2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF2A	0.39407674	0.05858586	47	4	FALSE	KIF2A	KIF2A	135.2	0	46	0	0.7437372	FALSE	1	KIF2A	135004	0.04573171
787462	taxon:9606	2.46368363	1.26E-04	179392	1902	microfibrillar associated protein 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0001527-&&-microfibril-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MFAP1				MFAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MFAP1	0.40589627	0.11840888	47	4	FALSE	MFAP1	MFAP1	184.4680851	0	47	0	0.75605273	FALSE	0	MFAP1	199030	0.05382494
787546	taxon:9606	2.50638097	9.60E-05	179212	1902	protein phosphatase 2 phosphatase activator	gene	biological_process-&-1&-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0035308-&&-negative regulation of protein dephosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0030472-&&-mitotic spindle organization in nucleus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0034704-&&-calcium channel complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008160-&&-protein tyrosine phosphatase activator activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:PTPA			KEGG-&-1&-hsa04931-&&-Insulin resistance	PTPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPA	0.39898164	0.13968548	47	4	FALSE	PTPA	PTPA	148.1914894	0	47	0	0.74893651	FALSE	0	PTPA	130034	0.04752933
787580	taxon:9606	2.52717819	1.02E-04	179145	1902	neural precursor cell expressed, developmentally down-regulated 9	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0040008-&&-regulation of growth|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030027-&&-lamellipodium-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NEDD9				NEDD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEDD9	0.39569825	0.11818182	47	4	FALSE	NEDD9	NEDD9	135.6222222	0	46	0	0.7454703	FALSE	1	NEDD9	140964	0.04536665
787679	taxon:9606	2.43800221	1.23E-04	178967	1902	Pim-1 proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007049-&&-cell cycle-%%-GO:0070561-&&-vitamin D receptor signaling pathway-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PIM1	PIM1	TRUE	KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer	PIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIM1	0.4101719	0.06464646	47	4	FALSE	PIM1	PIM1	157.2666667	0	46	0	0.76033297	FALSE	1	PIM1	170190	0.04413849
788233	taxon:9606	2.6351032	1.84E-04	178033	1902	SH3 domain containing GRB2 like 3, endophilin A3	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0006897-&&-endocytosis-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:SH3GL3			KEGG-&-1&-hsa04144-&&-Endocytosis	SH3GL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3GL3	0.37949178	0.07575758	47	4	FALSE	SH3GL3	SH3GL3	86.22222222	0	46	0	0.7274828	FALSE	1	SH3GL3	243706	0.03699881
788241	taxon:9606	2.76508587	6.12E-05	178022	1902	serine hydroxymethyltransferase 1	gene	biological_process-&-1&-GO:0009113-&&-purine nucleobase biosynthetic process-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0006231-&&-dTMP biosynthetic process-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0045329-&&-carnitine biosynthetic process-%%-GO:0006565-&&-L-serine catabolic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:1904482-&&-cellular response to tetrahydrofolate-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0051262-&&-protein tetramerization-%%-GO:0006563-&&-L-serine metabolic process-%%-GO:0019264-&&-glycine biosynthetic process from serine-%%-GO:0051289-&&-protein homotetramerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0070905-&&-serine binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004372-&&-glycine hydroxymethyltransferase activity-%%-GO:0008732-&&-L-allo-threonine aldolase activity-%%-GO:0042802-&&-identical protein binding	G:9606:SHMT1			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism-%%-hsa01523-&&-Antifolate resistance	SHMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHMT1	0.36165242	0.11515152	47	4	FALSE	SHMT1	SHMT1	118.2	0	46	0	0.70581902	FALSE	1	SHMT1	108686	0.07769732
788245	taxon:9606	2.73010871	1.07E-04	161625	1902	solute carrier family 25 member 41	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0015867-&&-ATP transport-%%-GO:0015866-&&-ADP transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005347-&&-ATP transmembrane transporter activity-%%-GO:0015217-&&-ADP transmembrane transporter activity	G:9606:SLC25A41				SLC25A41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A41	0.36628578	0.0453284	47	5	FALSE	SLC25A41	SLC25A41	68.12765957	0	47	0	0.71164855	FALSE	0	SLC25A41	109682	0.03946405
788253	taxon:9606	2.58815188	1.61E-04	178002	1902	regulator of G-protein signaling 2	gene	biological_process-&-1&-GO:0060087-&&-relaxation of vascular smooth muscle-%%-GO:0071877-&&-regulation of adrenergic receptor signaling pathway-%%-GO:0006417-&&-regulation of translation-%%-GO:0010519-&&-negative regulation of phospholipase activity-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0060452-&&-positive regulation of cardiac muscle contraction-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS2			KEGG-&-1&-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04022-&&-cGMP-PKG signaling pathway	RGS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS2	0.38637609	0.0333025	47	4	FALSE	RGS2	RGS2	104.1914894	0	47	0	0.73530802	FALSE	0	RGS2	170304	0.03992837
788324	taxon:9606	2.46951316	1.51E-04	177880	1902	seryl-tRNA synthetase	gene	biological_process-&-1&-GO:0016259-&&-selenocysteine metabolic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0008033-&&-tRNA processing-%%-GO:0006434-&&-seryl-tRNA aminoacylation-%%-GO:0006412-&&-translation-%%-GO:0097056-&&-selenocysteinyl-tRNA(Sec) biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0098619-&&-selenocysteine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004828-&&-serine-tRNA ligase activity-%%-GO:0003723-&&-RNA binding	G:9606:SARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	SARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SARS	0.40493811	0.10638298	47	4	FALSE	SARS	SARS	165.6170213	0	47	0	0.75508114	FALSE	0	SARS	206748	0.04907364
788386	taxon:9606	2.44241374	1.34E-04	177758	1902	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0061084-&&-negative regulation of protein refolding-%%-GO:0070389-&&-chaperone cofactor-dependent protein refolding|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0032564-&&-dATP binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ST13				ST13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ST13	0.40943104	0.1119334	47	4	FALSE	ST13	ST13	198.4680851	0	47	0	0.75959771	FALSE	0	ST13	219946	0.05652335
788448	taxon:9606	2.72538207	4.63E-04	177653	1902	solute carrier family 2 member 4	gene	biological_process-&-1&-GO:0046323-&&-glucose import-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0015758-&&-glucose transport-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0045471-&&-response to ethanol-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0044381-&&-glucose import in response to insulin stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1904659-&&-glucose transmembrane transport-%%-GO:0010021-&&-amylopectin biosynthetic process-%%-GO:0071470-&&-cellular response to osmotic stress|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0032593-&&-insulin-responsive compartment-%%-GO:0030315-&&-T-tubule-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane-%%-GO:0012505-&&-endomembrane system-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0016020-&&-membrane-%%-GO:0005771-&&-multivesicular body-%%-GO:0045121-&&-membrane raft-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005355-&&-glucose transmembrane transporter activity-%%-GO:0055056-&&-D-glucose transmembrane transporter activity	G:9606:SLC2A4	SLC2A4	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway	SLC2A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC2A4	0.36692103	0.01480111	47	4	FALSE	SLC2A4	SLC2A4	60.0212766	0	47	0	0.71243632	FALSE	0	SLC2A4	585528	0.03378656
788526	taxon:9606	2.67401922	4.19E-05	177501	1902	Spi-1 proto-oncogene	gene	biological_process-&-1&-GO:0044027-&&-hypermethylation of CpG island-%%-GO:0090241-&&-negative regulation of histone H4 acetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0060033-&&-anatomical structure regression-%%-GO:0030098-&&-lymphocyte differentiation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:1902262-&&-apoptotic process involved in blood vessel morphogenesis-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0045347-&&-negative regulation of MHC class II biosynthetic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:SPI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04380-&&-Osteoclast differentiation	SPI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPI1	0.37396889	0.16558742	47	4	FALSE	SPI1	SPI1	110.3404255	0	47	0	0.7209968	FALSE	0	SPI1	69502	0.05212565
788568	taxon:9606	2.71829211	9.66E-05	177417	1902	transgelin	gene	biological_process-&-1&-GO:0030855-&&-epithelial cell differentiation-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:TAGLN				TAGLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAGLN	0.36787805	0.12950971	47	4	FALSE	TAGLN	TAGLN	76.85106383	0	47	0	0.71361798	FALSE	0	TAGLN	110124	0.04242381
788579	taxon:9606	2.61367575	4.66E-05	177407	1902	TAL bHLH transcription factor 1, erythroid differentiation factor	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0030219-&&-megakaryocyte differentiation-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0030221-&&-basophil differentiation-%%-GO:0030097-&&-hemopoiesis-%%-GO:0045799-&&-positive regulation of chromatin assembly or disassembly-%%-GO:0060018-&&-astrocyte fate commitment-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0021527-&&-spinal cord association neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0007626-&&-locomotory behavior-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060375-&&-regulation of mast cell differentiation-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0030220-&&-platelet formation-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:0060217-&&-hemangioblast cell differentiation-%%-GO:0035855-&&-megakaryocyte development|cellular_component-&-1&-GO:0033193-&&-Lsd1/2 complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0019899-&&-enzyme binding	G:9606:TAL1				TAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAL1	0.38260293	0.15454545	47	4	FALSE	TAL1	TAL1	134.5555556	0	46	0	0.73105404	FALSE	1	TAL1	82068	0.05417674
788912	taxon:9606	2.52654798	8.69E-05	176624	1902	MAD1 mitotic arrest deficient like 1	gene	biological_process-&-1&-GO:0048538-&&-thymus development-%%-GO:0090235-&&-regulation of metaphase plate congression-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005813-&&-centrosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAD1L1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	MAD1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAD1L1	0.39579696	0.1020202	47	4	FALSE	MAD1L1	MAD1L1	142.4444444	0	46	0	0.74557534	FALSE	1	MAD1L1	127882	0.04706703
789096	taxon:9606	2.60122893	5.25E-05	176202	1902	cell division cycle 16	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CDC16			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC16	0.38443368	0.22016651	47	4	FALSE	CDC16	CDC16	121.5744681	0	47	0	0.73312851	FALSE	0	CDC16	90230	0.04766158
789098	taxon:9606	2.51756735	1.01E-04	176197	1902	Tax1 binding protein 1	gene	biological_process-&-1&-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032480-&&-negative regulation of type I interferon production|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding	G:9606:TAX1BP1			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	TAX1BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAX1BP1	0.39720884	0.11616162	47	4	FALSE	TAX1BP1	TAX1BP1	150.3111111	0	46	0	0.74707211	FALSE	1	TAX1BP1	146744	0.04912893
789260	taxon:9606	2.45360013	4.55E-05	175886	1902	eukaryotic translation initiation factor 3 subunit G	gene	biological_process-&-1&-GO:0075525-&&-viral translational termination-reinitiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3G			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3G	0.40756437	0.24040404	47	4	FALSE	EIF3G	EIF3G	192.0222222	0	46	0	0.75773331	FALSE	1	EIF3G	103806	0.0555427
789488	taxon:9606	2.38096739	1.42E-04	175358	1902	SEC24 homolog C, COPII coat complex component	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030127-&&-COPII vesicle coat|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:SEC24C			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC24C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC24C	0.41999735	0.14986124	47	4	FALSE	SEC24C	SEC24C	239.5106383	0	47	0	0.76983877	FALSE	0	SEC24C	230464	0.06143842
789594	taxon:9606	2.62375926	1.30E-04	175107	1902	aryl hydrocarbon receptor nuclear translocator 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0007420-&&-brain development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007417-&&-central nervous system development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032355-&&-response to estradiol-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0017162-&&-aryl hydrocarbon receptor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ARNT2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma	ARNT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARNT2	0.38113253	0.07171717	47	5	FALSE	ARNT2	ARNT2	97.37777778	0	46	0	0.72937346	FALSE	1	ARNT2	152516	0.04060471
789616	taxon:9606	2.65968174	6.51E-05	175049	1902	THO complex 1	gene	biological_process-&-1&-GO:0031297-&&-replication fork processing-%%-GO:0006915-&&-apoptotic process-%%-GO:0006396-&&-RNA processing-%%-GO:0007165-&&-signal transduction-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0048297-&&-negative regulation of isotype switching to IgA isotypes-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0046784-&&-viral mRNA export from host cell nucleus|cellular_component-&-1&-GO:0000445-&&-THO complex part of transcription export complex-%%-GO:0000346-&&-transcription export complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0000347-&&-THO complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:THOC1			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome	THOC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THOC1	0.37598484	0.12424242	47	4	FALSE	THOC1	THOC1	118.0222222	0	46	0	0.72338638	FALSE	1	THOC1	87030	0.0537265
789894	taxon:9606	2.4627383	1.05E-04	174409	1902	PDZ and LIM domain 5	gene	biological_process-&-1&-GO:0051963-&&-regulation of synapse assembly-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043005-&&-neuron projection-%%-GO:0016020-&&-membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0042805-&&-actinin binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005080-&&-protein kinase C binding	G:9606:PDLIM5				PDLIM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDLIM5	0.40605208	0.0906568	47	4	FALSE	PDLIM5	PDLIM5	174.1489362	0	47	0	0.75621028	FALSE	0	PDLIM5	173742	0.05127208
790110	taxon:9606	2.54324878	1.49E-05	173857	1902	DnaJ heat shock protein family (Hsp40) member C9	gene	biological_process-&-1&-GO:0035176-&&-social behavior-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031072-&&-heat shock protein binding	G:9606:DNAJC9				DNAJC9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC9	0.39319787	0.32284921	47	4	FALSE	DNAJC9	DNAJC9	296.8510638	0	47	0	0.74279187	FALSE	0	DNAJC9	66574	0.10208667
790115	taxon:9606	2.43831732	9.62E-05	173848	1902	PDS5 cohesin associated factor A	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PDS5A				PDS5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDS5A	0.41011889	0.12323232	47	4	FALSE	PDS5A	PDS5A	206.5111111	0	46	0	0.76028045	FALSE	1	PDS5A	205536	0.0580115
790253	taxon:9606	2.46573184	1.69E-05	173511	1902	U2 snRNP associated SURP domain containing	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:U2SURP			KEGG-&-1&-hsa03040-&&-Spliceosome	U2SURP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-U2SURP	0.40555911	0.28492137	47	4	FALSE	U2SURP	U2SURP	335.2765957	0	47	0	0.75571136	FALSE	0	U2SURP	76466	0.09874973
790300	taxon:9606	2.58074681	4.95E-05	173384	1902	peroxiredoxin 5	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0016480-&&-negative regulation of transcription from RNA polymerase III promoter-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0098869-&&-cellular oxidant detoxification|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0008379-&&-thioredoxin peroxidase activity-%%-GO:0004601-&&-peroxidase activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005102-&&-receptor binding-%%-GO:0001016-&&-RNA polymerase III regulatory region DNA binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:PRDX5			KEGG-&-1&-hsa04146-&&-Peroxisome	PRDX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDX5	0.38748474	0.12950971	47	4	FALSE	PRDX5	PRDX5	116.9574468	0	47	0	0.7365422	FALSE	0	PRDX5	90444	0.04380476
790562	taxon:9606	2.59067276	9.01E-05	172135	1902	cysteine and histidine rich domain containing 1	gene	biological_process-&-1&-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:2000299-&&-negative regulation of Rho-dependent protein serine/threonine kinase activity-%%-GO:0010824-&&-regulation of centrosome duplication|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043531-&&-ADP binding-%%-GO:0005515-&&-protein binding	G:9606:CHORDC1				CHORDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHORDC1	0.38600012	0.08787879	47	4	FALSE	CHORDC1	CHORDC1	110.4888889	0	46	0	0.73488787	FALSE	1	CHORDC1	115020	0.04165722
790658	taxon:9606	2.56940287	4.74E-05	171565	1902	mitochondrial ribosomal protein S28	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:MRPS28				MRPS28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS28	0.38919549	0.21924144	47	4	FALSE	MRPS28	MRPS28	211.8723404	0	47	0	0.73843286	FALSE	0	MRPS28	121088	0.07709282
790730	taxon:9606	2.63447298	2.51E-04	154981	1902	neutrophil cytosolic factor 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042554-&&-superoxide anion generation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0045730-&&-respiratory burst-%%-GO:0006968-&&-cellular defense response-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0071800-&&-podosome assembly|cellular_component-&-1&-GO:0043020-&&-NADPH oxidase complex-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0002102-&&-podosome-%%-GO:0030425-&&-dendrite-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0032010-&&-phagolysosome-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0016176-&&-superoxide-generating NADPH oxidase activator activity	G:9606:NCF1	NCF1	TRUE	KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation	NCF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCF1	0.37958256	0.13232323	47	4	FALSE	NCF1	NCF1	104.2888889	0	46	0	0.72758784	FALSE	1	NCF1	611268	0.04502974
790784	taxon:9606	2.63447298	2.51E-04	154838	1902	neutrophil cytosolic factor 1C pseudogene	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0071800-&&-podosome assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0002102-&&-podosome|molecular_function-&-1&-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0016176-&&-superoxide-generating NADPH oxidase activator activity	G:9606:NCF1C				NCF1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCF1C	0.37958256	0.13232323	47	4	FALSE	NCF1C	NCF1C	104.2888889	0	46	0	0.72758784	FALSE	1	NCF1C	611268	0.04502974
790887	taxon:9606	2.61477864	7.18E-05	170774	1902	NMD3 ribosome export adaptor	gene	biological_process-&-1&-GO:1904751-&&-positive regulation of protein localization to nucleolus-%%-GO:1902680-&&-positive regulation of RNA biosynthetic process-%%-GO:0000055-&&-ribosomal large subunit export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:NMD3			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03013-&&-RNA transport	NMD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NMD3	0.38244155	0.08695652	47	4	FALSE	NMD3	NMD3	102.4680851	0	47	0	0.73087023	FALSE	0	NMD3	92504	0.04163602
791120	taxon:9606	2.43894753	7.24E-05	169985	1902	minichromosome maintenance 10 replication initiation factor	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MCM10				MCM10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCM10	0.41001292	0.1480111	47	4	FALSE	MCM10	MCM10	181.8723404	0	47	0	0.76017541	FALSE	0	MCM10	149498	0.05101846
791411	taxon:9606	2.47817867	1.33E-04	168748	1902	kinesin light chain 2	gene	biological_process-&-1&-GO:0007018-&&-microtubule-based movement-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005871-&&-kinesin complex-%%-GO:0016938-&&-kinesin I complex-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0019894-&&-kinesin binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:KLC2			KEGG-&-1&-hsa05132-&&-Salmonella infection	KLC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLC2	0.40352216	0.11919192	47	4	FALSE	KLC2	KLC2	150.3777778	0	46	0	0.75363689	FALSE	1	KLC2	172758	0.04534969
791807	taxon:9606	2.58909721	7.58E-05	166777	1902	ligand dependent nuclear receptor corepressor	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:LCOR				LCOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCOR	0.38623501	0.20444033	47	4	FALSE	LCOR	LCOR	197.8510638	0	47	0	0.73515046	FALSE	0	LCOR	129920	0.07538875
791852	taxon:9606	2.42949425	8.80E-05	182973	1902	ABL proto-oncogene 2, non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:0010863-&&-positive regulation of phospholipase C activity-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007165-&&-signal transduction-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0005524-&&-ATP binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:ABL2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05416-&&-Viral myocarditis-%%-hsa04012-&&-ErbB signaling pathway	ABL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABL2	0.4116083	0.24343434	47	4	FALSE	ABL2	ABL2	192.0888889	0	46	0	0.76175096	FALSE	1	ABL2	151942	0.05333951
791955	taxon:9606	2.38459115	6.84E-05	166427	1902	dedicator of cytokinesis 7	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007409-&&-axonogenesis-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0022027-&&-interkinetic nuclear migration-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0045200-&&-establishment of neuroblast polarity-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0045178-&&-basal part of cell-%%-GO:0030426-&&-growth cone-%%-GO:0043005-&&-neuron projection-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0030424-&&-axon-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0048365-&&-Rac GTPase binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:DOCK7				DOCK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOCK7	0.4193591	0.11563367	47	4	FALSE	DOCK7	DOCK7	246.6808511	0	47	0	0.76923481	FALSE	0	DOCK7	181448	0.06341389
792247	taxon:9606	2.74649441	6.14E-05	182353	1902	ATPase H+ transporting V1 subunit C1	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0015992-&&-proton transport-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016469-&&-proton-transporting two-sector ATPase complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0000221-&&-vacuolar proton-transporting V-type ATPase, V1 domain|molecular_function-&-1&-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism-%%-GO:0005515-&&-protein binding-%%-GO:0008553-&&-hydrogen-exporting ATPase activity, phosphorylative mechanism-%%-GO:0005215-&&-transporter activity	G:9606:ATP6V1C1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05165-&&-Human papillomavirus infection	ATP6V1C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1C1	0.3641005	0.1040404	47	4	FALSE	ATP6V1C1	ATP6V1C1	61.55555556	0	46	0	0.7089176	FALSE	1	ATP6V1C1	64562	0.03743475
792267	taxon:9606	2.54813298	1.52E-04	182313	1902	cell division cycle 6	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0051984-&&-positive regulation of chromosome segregation-%%-GO:0006260-&&-DNA replication-%%-GO:0000076-&&-DNA replication checkpoint-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0051301-&&-cell division-%%-GO:1904117-&&-cellular response to vasopressin-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0007089-&&-traversing start control point of mitotic cell cycle-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0051233-&&-spindle midzone-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:CDC6			KEGG-&-1&-hsa04110-&&-Cell cycle	CDC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC6	0.3924442	0.17761332	47	4	FALSE	CDC6	CDC6	151.9361702	0	47	0	0.74197784	FALSE	0	CDC6	188612	0.05270038
792540	taxon:9606	2.56451867	1.20E-04	181833	1902	caspase 4	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0006508-&&-proteolysis-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:1904646-&&-cellular response to beta-amyloid|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0072557-&&-IPAF inflammasome complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0097169-&&-AIM2 inflammasome complex-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP4			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	CASP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP4	0.38993672	0.06464646	47	4	FALSE	CASP4	CASP4	117.8	0	46	0	0.73924689	FALSE	1	CASP4	155346	0.04270959
792663	taxon:9606	2.58295258	1.50E-04	181597	1902	DAB1, reelin adaptor protein	gene	biological_process-&-1&-GO:0021942-&&-radial glia guided migration of Purkinje cell-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007628-&&-adult walking behavior-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0021517-&&-ventral spinal cord development-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0097477-&&-lateral motor column neuron migration-%%-GO:0042493-&&-response to drug-%%-GO:0021813-&&-cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0016358-&&-dendrite development-%%-GO:0051645-&&-Golgi localization-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0021589-&&-cerebellum structural organization-%%-GO:0007494-&&-midgut development|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0045177-&&-apical part of cell-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0005903-&&-brush border-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0005515-&&-protein binding	G:9606:DAB1				DAB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAB1	0.38715384	0.05920444	47	4	FALSE	DAB1	DAB1	96.34042553	0	47	0	0.73617457	FALSE	0	DAB1	160094	0.03663762
792670	taxon:9606	2.48589885	5.12E-05	181585	1902	death associated protein kinase 1	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006915-&&-apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:DAPK1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa05200-&&-Pathways in cancer	DAPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAPK1	0.40226898	0.12323232	47	4	FALSE	DAPK1	DAPK1	172.6222222	0	46	0	0.75235019	FALSE	1	DAPK1	109918	0.05278798
792711	taxon:9606	2.48195998	6.65E-05	165132	1902	ribonucleoprotein, PTB binding 1	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003676-&&-nucleic acid binding	G:9606:RAVER1				RAVER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAVER1	0.40290738	0.1119334	47	4	FALSE	RAVER1	RAVER1	186.5957447	0	47	0	0.75300667	FALSE	0	RAVER1	132020	0.0566837
792720	taxon:9606	2.51347093	1.09E-04	181503	1902	diaphanous related formin 1	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071420-&&-cellular response to histamine-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0035372-&&-protein localization to microtubule-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005886-&&-plasma membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044325-&&-ion channel binding	G:9606:DIAPH1			KEGG-&-1&-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05131-&&-Shigellosis	DIAPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIAPH1	0.3978562	0.08989899	47	4	FALSE	DIAPH1	DIAPH1	151.9333333	0	46	0	0.74775484	FALSE	1	DIAPH1	147834	0.04925373
792753	taxon:9606	2.41815031	7.97E-05	181432	1902	flap structure-specific endonuclease 1	gene	biological_process-&-1&-GO:0045876-&&-positive regulation of sister chromatid cohesion-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006260-&&-DNA replication-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0007613-&&-memory-%%-GO:0009650-&&-UV protection-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006281-&&-DNA repair-%%-GO:0043137-&&-DNA replication, removal of RNA primer|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0017108-&&-5'-flap endonuclease activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0004523-&&-RNA-DNA hybrid ribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0008409-&&-5'-3' exonuclease activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008309-&&-double-stranded DNA exodeoxyribonuclease activity-%%-GO:0004527-&&-exonuclease activity-%%-GO:0048256-&&-flap endonuclease activity	G:9606:FEN1			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa03450-&&-Non-homologous end-joining-%%-hsa03030-&&-DNA replication	FEN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FEN1	0.41353922	0.11748381	47	4	FALSE	FEN1	FEN1	195.4042553	0	47	0	0.76364162	FALSE	0	FEN1	147708	0.0531394
792791	taxon:9606	2.69733732	1.00E-04	164972	1902	NudC domain containing 2	gene	biological_process-&-1&-GO:0032502-&&-developmental process-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:NUDCD2				NUDCD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDCD2	0.37073598	0.02682701	47	4	FALSE	NUDCD2	NUDCD2	72.46808511	0	47	0	0.71711045	FALSE	0	NUDCD2	108288	0.03722854
792827	taxon:9606	2.52323933	1.67E-04	181299	1902	erythrocyte membrane protein band 4.1 like 1	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:EPB41L1				EPB41L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41L1	0.39631595	0.0906568	47	4	FALSE	EPB41L1	EPB41L1	132.5957447	0	47	0	0.74612678	FALSE	0	EPB41L1	198442	0.04375435
792843	taxon:9606	2.62880101	6.71E-05	181278	1902	erythropoietin receptor	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0046697-&&-decidualization-%%-GO:0007507-&&-heart development-%%-GO:0038162-&&-erythropoietin-mediated signaling pathway-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004900-&&-erythropoietin receptor activity-%%-GO:0042802-&&-identical protein binding	G:9606:EPOR			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	EPOR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPOR	0.38040156	0.24040404	47	4	FALSE	EPOR	EPOR	126.6444444	0	46	0	0.72853317	FALSE	1	EPOR	107670	0.05388984
792931	taxon:9606	2.54466677	4.96E-05	181123	1902	fatty acid binding protein 5	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0009611-&&-response to wounding-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0015758-&&-glucose transport-%%-GO:0006006-&&-glucose metabolic process|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005504-&&-fatty acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:FABP5			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	FABP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FABP5	0.39297876	0.21276596	47	4	FALSE	FABP5	FABP5	163.3191489	0	47	0	0.74255554	FALSE	0	FABP5	111798	0.05641165
793059	taxon:9606	2.69544667	3.53E-05	164433	1902	ankyrin repeat and SOCS box containing 9	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045732-&&-positive regulation of protein catabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ASB9				ASB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB9	0.37099603	0.07585569	47	4	FALSE	ASB9	ASB9	144.2340426	0	47	0	0.71742556	FALSE	0	ASB9	94538	0.07345362
793143	taxon:9606	2.5024421	6.40E-05	180649	1902	GLI family zinc finger 1	gene	biological_process-&-1&-GO:0021696-&&-cerebellar cortex morphogenesis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097421-&&-liver regeneration-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0007418-&&-ventral midline development-%%-GO:2000345-&&-regulation of hepatocyte proliferation-%%-GO:0021983-&&-pituitary gland development-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0021938-&&-smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation-%%-GO:0030324-&&-lung development-%%-GO:0060032-&&-notochord regression-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0009611-&&-response to wounding-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0097542-&&-ciliary tip-%%-GO:0097546-&&-ciliary base-%%-GO:0005930-&&-axoneme-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:GLI1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05217-&&-Basal cell carcinoma	GLI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLI1	0.39960965	0.08418131	47	4	FALSE	GLI1	GLI1	159.0212766	0	47	0	0.74959298	FALSE	0	GLI1	120376	0.05052515
787046	taxon:9606	2.52434221	6.51E-05	180164	1902	isocitrate dehydrogenase 3 (NAD(+)) alpha	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0004449-&&-isocitrate dehydrogenase (NAD+) activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:IDH3A			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism	IDH3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDH3A	0.3961428	0.15169082	46	4	FALSE	IDH3A	IDH3A	149.0869565	0	46	0	0.74594297	FALSE	0	IDH3A	108150	0.04929598
787049	taxon:9606	2.61714196	6.28E-05	180166	1902	isocitrate dehydrogenase (NADP(+)) 1, cytosolic	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0006740-&&-NADPH regeneration-%%-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0008585-&&-female gonad development-%%-GO:0006097-&&-glyoxylate cycle-%%-GO:0060696-&&-regulation of phospholipid catabolic process-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0071071-&&-regulation of phospholipid biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006102-&&-isocitrate metabolic process-%%-GO:0048545-&&-response to steroid hormone|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005777-&&-peroxisome-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005782-&&-peroxisomal matrix|molecular_function-&-1&-GO:0004450-&&-isocitrate dehydrogenase (NADP+) activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005102-&&-receptor binding-%%-GO:0051287-&&-NAD binding-%%-GO:0051990-&&-(R)-2-hydroxyglutarate dehydrogenase activity-%%-GO:0050661-&&-NADP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:IDH1			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer	IDH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDH1	0.3820962	0.12896406	46	4	FALSE	IDH1	IDH1	102.3863636	0	45	0	0.73047634	FALSE	1	IDH1	89536	0.04135739
787160	taxon:9606	2.64723491	2.11E-04	179954	1902	LDL receptor related protein 2	gene	biological_process-&-1&-GO:0042359-&&-vitamin D metabolic process-%%-GO:0035904-&&-aorta development-%%-GO:0061024-&&-membrane organization-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0003281-&&-ventricular septum development-%%-GO:0006897-&&-endocytosis-%%-GO:0008283-&&-cell proliferation-%%-GO:0030900-&&-forebrain development-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0031526-&&-brush border membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043235-&&-receptor complex-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0042954-&&-lipoprotein transporter activity	G:9606:LRP2	LRP2	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04918-&&-Thyroid hormone synthesis	LRP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRP2	0.37775265	0.04016913	46	4	FALSE	LRP2	LRP2	74.68181818	0	45	0	0.72546085	FALSE	1	LRP2	169304	0.03333741
787189	taxon:9606	2.66204506	4.80E-05	179906	1902	SMAD family member 6	gene	biological_process-&-1&-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0043627-&&-response to estrogen-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0007352-&&-zygotic specification of dorsal/ventral axis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0001657-&&-ureteric bud development-%%-GO:0006955-&&-immune response-%%-GO:0003281-&&-ventricular septum development-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0035904-&&-aorta development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0010991-&&-negative regulation of SMAD protein complex assembly-%%-GO:0045444-&&-fat cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0070698-&&-type I activin receptor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0030617-&&-transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070411-&&-I-SMAD binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:SMAD6			KEGG-&-1&-hsa04350-&&-TGF-beta signaling pathway	SMAD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAD6	0.37565104	0.15539112	46	4	FALSE	SMAD6	SMAD6	101.4545455	0	45	0	0.72299249	FALSE	1	SMAD6	73026	0.04665788
787612	taxon:9606	2.42713093	2.22E-04	179101	1902	nerve growth factor receptor	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006955-&&-immune response-%%-GO:2001273-&&-regulation of glucose import in response to insulin stimulus-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007411-&&-axon guidance-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:1903588-&&-negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043121-&&-neurotrophin binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0048406-&&-nerve growth factor binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0015026-&&-coreceptor activity-%%-GO:0004872-&&-receptor activity	G:9606:NGFR	NGFR	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	NGFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NGFR	0.41200909	0.09302326	46	4	FALSE	NGFR	NGFR	172.75	0	45	0	0.76214485	FALSE	1	NGFR	242180	0.047902
787824	taxon:9606	2.53789192	5.44E-05	162363	1902	leucine rich repeats and WD repeat domain containing 1	gene	biological_process-&-1&-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006325-&&-chromatin organization-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0031933-&&-telomeric heterochromatin-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008327-&&-methyl-CpG binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035064-&&-methylated histone binding	G:9606:LRWD1				LRWD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRWD1	0.39402781	0.15942029	46	4	FALSE	LRWD1	LRWD1	202.6521739	0	46	0	0.74368468	FALSE	0	LRWD1	133742	0.06869064
787932	taxon:9606	2.5769655	6.48E-05	178566	1902	origin recognition complex subunit 5	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000808-&&-origin recognition complex-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding-%%-GO:0003688-&&-DNA replication origin binding	G:9606:ORC5			KEGG-&-1&-hsa04110-&&-Cell cycle	ORC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORC5	0.38805331	0.24524313	46	4	FALSE	ORC5	ORC5	189.7727273	0	45	0	0.73717242	FALSE	1	ORC5	109226	0.06987338
787961	taxon:9606	2.67606743	1.34E-04	178503	1902	paired box 6	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0061303-&&-cornea development in camera-type eye-%%-GO:0001568-&&-blood vessel development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001654-&&-eye development-%%-GO:0003322-&&-pancreatic A cell development-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0007417-&&-central nervous system development-%%-GO:0007601-&&-visual perception-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009611-&&-response to wounding-%%-GO:0042593-&&-glucose homeostasis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:PAX6	PAX6	TRUE	KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PAX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAX6	0.37368266	0.06553911	46	4	FALSE	PAX6	PAX6	91.36363636	0	45	0	0.72065543	FALSE	1	PAX6	147810	0.04367608
788192	taxon:9606	2.73026627	1.62E-05	178101	1902	AT-rich interaction domain 4A	gene	biological_process-&-1&-GO:0048821-&&-erythrocyte development-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0097368-&&-establishment of Sertoli cell barrier-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis-%%-GO:0036124-&&-histone H3-K9 trimethylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0034773-&&-histone H4-K20 trimethylation-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016575-&&-histone deacetylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004407-&&-histone deacetylase activity	G:9606:ARID4A				ARID4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARID4A	0.36626464	0.23381643	46	5	FALSE	ARID4A	ARID4A	171.9347826	0	46	0	0.71162229	FALSE	0	ARID4A	47434	0.09441778
788212	taxon:9606	2.55805893	3.59E-05	178070	1902	RecQ like helicase	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005694-&&-chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0036310-&&-annealing helicase activity-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0009378-&&-four-way junction helicase activity	G:9606:RECQL				RECQL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RECQL	0.39092141	0.19238901	46	4	FALSE	RECQL	RECQL	228.4545455	0	45	0	0.74032351	FALSE	1	RECQL	107254	0.08040973
788305	taxon:9606	2.52197889	3.80E-04	177917	1902	receptor-like tyrosine kinase	gene	biological_process-&-1&-GO:0036518-&&-chemorepulsion of dopaminergic neuron axon-%%-GO:0007165-&&-signal transduction-%%-GO:0007416-&&-synapse assembly-%%-GO:0031175-&&-neuron projection development-%%-GO:0007409-&&-axonogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:1904953-&&-Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0022008-&&-neurogenesis-%%-GO:0022038-&&-corpus callosum development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0071679-&&-commissural neuron axon guidance-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007411-&&-axon guidance-%%-GO:0030182-&&-neuron differentiation-%%-GO:0033278-&&-cell proliferation in midbrain-%%-GO:1904938-&&-planar cell polarity pathway involved in axon guidance-%%-GO:0035567-&&-non-canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:1904929-&&-coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:RYK			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04310-&&-Wnt signaling pathway	RYK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RYK	0.39651403	0.04154589	46	4	FALSE	RYK	RYK	131.4565217	0	46	0	0.74633685	FALSE	0	RYK	416300	0.04357947
788584	taxon:9606	2.54639987	1.13E-04	177398	1902	TARBP2, RISC loading complex RNA binding subunit	gene	biological_process-&-1&-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0046782-&&-regulation of viral transcription-%%-GO:0035087-&&-siRNA loading onto RISC involved in RNA interference-%%-GO:0007338-&&-single fertilization-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0030423-&&-targeting of mRNA for destruction involved in RNA interference-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0007286-&&-spermatid development-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0050689-&&-negative regulation of defense response to virus by host-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016442-&&-RISC complex-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0035068-&&-micro-ribonucleoprotein complex|molecular_function-&-1&-GO:0035197-&&-siRNA binding-%%-GO:0070883-&&-pre-miRNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0036002-&&-pre-mRNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:TARBP2				TARBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARBP2	0.3927113	0.0845666	46	4	FALSE	TARBP2	TARBP2	120.7045455	0	45	0	0.74226669	FALSE	1	TARBP2	133266	0.04180589
788600	taxon:9606	2.54167323	1.12E-04	177367	1902	HNF1 homeobox A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0046323-&&-glucose import-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0035565-&&-regulation of pronephros size-%%-GO:0035623-&&-renal glucose absorption-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:HNF1A	HNF1A	TRUE	KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	HNF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNF1A	0.39344161	0.11099366	46	4	FALSE	HNF1A	HNF1A	153.3409091	0	45	0	0.74305446	FALSE	1	HNF1A	163056	0.05293868
788608	taxon:9606	2.5936663	1.13E-04	160962	1902	ataxin 1 like	gene	biological_process-&-1&-GO:1902035-&&-positive regulation of hematopoietic stem cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048286-&&-lung alveolus development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ATXN1L				ATXN1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN1L	0.38555461	0.05391121	46	4	FALSE	ATXN1L	ATXN1L	96.38636364	0	45	0	0.73438895	FALSE	1	ATXN1L	129144	0.03731185
788635	taxon:9606	2.52954152	3.47E-05	177276	1902	transcription factor binding to IGHM enhancer 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0002250-&&-adaptive immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0006959-&&-humoral immune response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:TFE3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04137-&&-Mitophagy - animal	TFE3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFE3	0.39532856	0.06871036	46	4	FALSE	TFE3	TFE3	158.3636364	0	45	0	0.74507641	FALSE	1	TFE3	78526	0.05289104
789245	taxon:9606	2.72128565	9.04E-05	175900	1902	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	gene	biological_process-&-1&-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016236-&&-macroautophagy-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0000165-&&-MAPK cascade-%%-GO:0034613-&&-cellular protein localization-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071986-&&-Ragulator complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0032947-&&-protein complex scaffold-%%-GO:0019209-&&-kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:LAMTOR3			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	LAMTOR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMTOR3	0.36747337	0.03864734	46	4	FALSE	LAMTOR3	LAMTOR3	72.47826087	0	46	0	0.71311906	FALSE	0	LAMTOR3	99274	0.04008265
789553	taxon:9606	2.65826375	1.01E-04	175197	1902	GIT ArfGAP 2	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0048266-&&-behavioral response to pain-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:GIT2			KEGG-&-1&-hsa04144-&&-Endocytosis	GIT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIT2	0.3761854	0.05708245	46	4	FALSE	GIT2	GIT2	85.88636364	0	45	0	0.72362271	FALSE	1	GIT2	105548	0.03942742
789852	taxon:9606	2.57302663	2.60E-04	174511	1902	OS9, endoplasmic reticulum lectin	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006621-&&-protein retention in ER lumen-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1904153-&&-negative regulation of retrograde protein transport, ER to cytosol-%%-GO:0006605-&&-protein targeting-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0000836-&&-Hrd1p ubiquitin ligase complex-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0001948-&&-glycoprotein binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding	G:9606:OS9			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	OS9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OS9	0.38864736	0.10465116	46	4	FALSE	OS9	OS9	110.0227273	0	45	0	0.7378289	FALSE	1	OS9	267626	0.04071864
789860	taxon:9606	2.40507326	1.47E-04	174493	1902	fermitin family member 2	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0034329-&&-cell junction assembly-%%-GO:0033622-&&-integrin activation-%%-GO:0072657-&&-protein localization to membrane-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0031674-&&-I band-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:FERMT2				FERMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FERMT2	0.41578775	0.13913043	46	4	FALSE	FERMT2	FERMT2	188.0434783	0	46	0	0.76582112	FALSE	0	FERMT2	209400	0.05006658
789945	taxon:9606	2.5323775	4.15E-05	174287	1902	zinc finger MYND-type containing 11	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0034243-&&-regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0042393-&&-histone binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ZMYND11				ZMYND11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMYND11	0.39488583	0.13424947	46	4	FALSE	ZMYND11	ZMYND11	174.3863636	0	45	0	0.74460375	FALSE	1	ZMYND11	88560	0.05858993
790149	taxon:9606	2.55175674	7.03E-05	173761	1902	TPX2, microtubule nucleation factor	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0060236-&&-regulation of mitotic spindle organization-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0043203-&&-axon hillock-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061676-&&-importin-alpha family protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding	G:9606:TPX2				TPX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPX2	0.39188689	0.06236786	46	4	FALSE	TPX2	TPX2	159.6590909	0	45	0	0.74137388	FALSE	1	TPX2	127514	0.05624499
790323	taxon:9606	2.49960611	1.64E-04	173313	1902	atlastin GTPase 3	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0071782-&&-endoplasmic reticulum tubular network-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding	G:9606:ATL3				ATL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATL3	0.40006303	0.06763285	46	4	FALSE	ATL3	ATL3	129.3043478	0	46	0	0.75006565	FALSE	0	ATL3	178492	0.04091667
790421	taxon:9606	2.67843075	4.62E-05	173037	1902	mitochondrial carrier 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045161-&&-neuronal ion channel clustering-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006810-&&-transport-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MTCH1				MTCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTCH1	0.37335294	0.16231884	46	4	FALSE	MTCH1	MTCH1	104.6086957	0	46	0	0.72026154	FALSE	0	MTCH1	71792	0.05034766
790425	taxon:9606	2.55443517	6.25E-05	173024	1902	translocase of inner mitochondrial membrane 13	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0045039-&&-protein import into mitochondrial inner membrane-%%-GO:0072321-&&-chaperone-mediated protein transport|cellular_component-&-1&-GO:0042719-&&-mitochondrial intermembrane space protein transporter complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0008565-&&-protein transporter activity	G:9606:TIMM13				TIMM13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMM13	0.39147598	0.11111111	46	4	FALSE	TIMM13	TIMM13	158.8043478	0	46	0	0.74092747	FALSE	0	TIMM13	101610	0.05555386
790432	taxon:9606	2.68236962	2.07E-05	173001	1902	SRSF protein kinase 3	gene	biological_process-&-1&-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0060537-&&-muscle tissue development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:SRPK3				SRPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPK3	0.3728047	0.2115942	46	4	FALSE	SRPK3	SRPK3	129.7173913	0	46	0	0.71960506	FALSE	0	SRPK3	40174	0.06250393
790593	taxon:9606	2.57665039	5.61E-05	172026	1902	OTU deubiquitinase 4	gene	biological_process-&-1&-GO:0071108-&&-protein K48-linked deubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:OTUD4				OTUD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUD4	0.38810077	0.09468599	46	4	FALSE	OTUD4	OTUD4	176.326087	0	46	0	0.73722494	FALSE	0	OTUD4	134818	0.0656713
790640	taxon:9606	2.66976524	1.24E-04	171690	1902	coiled-coil alpha-helical rod protein 1	gene	biological_process-&-1&-GO:0006611-&&-protein export from nucleus-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus	G:9606:CCHCR1				CCHCR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCHCR1	0.37456477	0.08985201	46	4	FALSE	CCHCR1	CCHCR1	89.68181818	0	45	0	0.72170579	FALSE	1	CCHCR1	129760	0.04199906
790728	taxon:9606	2.61146999	3.78E-05	171368	1902	PHD finger protein 20-like 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PHF20L1				PHF20L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF20L1	0.38292609	0.36811594	46	4	FALSE	PHF20L1	PHF20L1	229.173913	0	46	0	0.73142167	FALSE	0	PHF20L1	93950	0.09217916
790752	taxon:9606	2.4926737	1.27E-04	171328	1902	stromal cell derived factor 4	gene	biological_process-&-1&-GO:0045444-&&-fat cell differentiation-%%-GO:0017156-&&-calcium ion regulated exocytosis-%%-GO:0045471-&&-response to ethanol-%%-GO:0009650-&&-UV protection-%%-GO:0021549-&&-cerebellum development-%%-GO:0070625-&&-zymogen granule exocytosis|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0005770-&&-late endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0032059-&&-bleb-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:SDF4				SDF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDF4	0.40117565	0.06763285	46	4	FALSE	SDF4	SDF4	155.9130435	0	46	0	0.75122105	FALSE	0	SDF4	171820	0.04832942
790753	taxon:9606	2.65527021	4.58E-05	171331	1902	inhibitor of growth family member 4	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0006915-&&-apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006473-&&-protein acetylation-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ING4				ING4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ING4	0.37660951	0.17547569	46	4	FALSE	ING4	ING4	182.2727273	0	45	0	0.72412163	FALSE	1	ING4	100320	0.0814665
790797	taxon:9606	2.53615882	6.17E-05	171177	1902	striatin 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0032355-&&-response to estradiol|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005515-&&-protein binding	G:9606:STRN3				STRN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRN3	0.39429707	0.22222222	46	4	FALSE	STRN3	STRN3	141.1086957	0	46	0	0.74397353	FALSE	0	STRN3	105906	0.04771574
790852	taxon:9606	2.55301717	2.19E-04	170892	1902	cytochrome c, somatic	gene	biological_process-&-1&-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0006123-&&-mitochondrial electron transport, cytochrome c to oxygen-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045333-&&-cellular respiration-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c|cellular_component-&-1&-GO:0070469-&&-respiratory chain-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0045155-&&-electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	G:9606:CYCS			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05134-&&-Legionellosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05416-&&-Viral myocarditis-%%-hsa04210-&&-Apoptosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa01524-&&-Platinum drug resistance	CYCS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYCS	0.39169341	0.0705314	46	4	FALSE	CYCS	CYCS	140.6521739	0	46	0	0.7411638	FALSE	0	CYCS	250568	0.04922915
790872	taxon:9606	2.72947849	1.65E-04	170815	1902	ADAMTS like 4	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0036066-&&-protein O-linked fucosylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0002064-&&-epithelial cell development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005614-&&-interstitial matrix|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:ADAMTSL4				ADAMTSL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAMTSL4	0.36637035	0.1178744	46	4	FALSE	ADAMTSL4	ADAMTSL4	64.19565217	0	46	0	0.71175358	FALSE	0	ADAMTSL4	203122	0.03691267
791038	taxon:9606	2.48069954	1.31E-04	170281	1902	dynein axonemal assembly factor 5	gene	biological_process-&-1&-GO:0036158-&&-outer dynein arm assembly-%%-GO:0036159-&&-inner dynein arm assembly-%%-GO:0003341-&&-cilium movement|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031514-&&-motile cilium|molecular_function-&-1&-GO:0045505-&&-dynein intermediate chain binding	G:9606:DNAAF5				DNAAF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAAF5	0.4031121	0.06763285	46	4	FALSE	DNAAF5	DNAAF5	150.5434783	0	46	0	0.75321674	FALSE	0	DNAAF5	188450	0.0458032
791080	taxon:9606	2.42240429	1.16E-04	170123	1902	Fanconi anemia complementation group I	gene	biological_process-&-1&-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0070182-&&-DNA polymerase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FANCI			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCI	0.41281301	0.09951691	46	4	FALSE	FANCI	FANCI	203.2608696	0	46	0	0.76293262	FALSE	0	FANCI	209538	0.05563955
791135	taxon:9606	2.78194423	5.95E-05	169934	1902	chromosome 20 open reading frame 24	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:C20orf24				C20orf24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C20orf24	0.35946084	0.04830918	46	4	FALSE	C20orf24	C20orf24	64.65217391	0	46	0	0.7030093	FALSE	0	C20orf24	77996	0.04375848
791159	taxon:9606	2.51488892	1.24E-05	169862	1902	DEAD-box helicase 27	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:DDX27				DDX27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX27	0.39763188	0.37294686	46	4	FALSE	DDX27	DDX27	245.0652174	0	46	0	0.74751851	FALSE	0	DDX27	44428	0.07925783
791201	taxon:9606	2.64455648	1.07E-04	169737	1902	forkhead box J2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:FOXJ2				FOXJ2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXJ2	0.37813524	0.05073996	46	4	FALSE	FOXJ2	FOXJ2	91.97727273	0	45	0	0.72590725	FALSE	1	FOXJ2	120978	0.04010578
791258	taxon:9606	2.55081141	7.43E-05	169483	1902	RAD18, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0006301-&&-postreplication repair-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0051984-&&-positive regulation of chromosome segregation-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0009411-&&-response to UV-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005657-&&-replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0042405-&&-nuclear inclusion body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0097505-&&-Rad6-Rad18 complex-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0000403-&&-Y-form DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003684-&&-damaged DNA binding	G:9606:RAD18				RAD18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD18	0.39203212	0.0961945	46	4	FALSE	RAD18	RAD18	144.4772727	0	45	0	0.74153143	FALSE	1	RAD18	112156	0.05041597
791615	taxon:9606	2.61241531	3.54E-05	167800	1902	euchromatic histone lysine methyltransferase 1	gene	biological_process-&-1&-GO:0006306-&&-DNA methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0009790-&&-embryo development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060992-&&-response to fungicide-%%-GO:0070734-&&-histone H3-K27 methylation-%%-GO:0006325-&&-chromatin organization-%%-GO:0016571-&&-histone methylation-%%-GO:0051567-&&-histone H3-K9 methylation-%%-GO:0018027-&&-peptidyl-lysine dimethylation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0002039-&&-p53 binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0046976-&&-histone methyltransferase activity (H3-K27 specific)	G:9606:EHMT1			KEGG-&-1&-hsa00310-&&-Lysine degradation-%%-hsa04211-&&-Longevity regulating pathway	EHMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHMT1	0.38278753	0.29069767	46	4	FALSE	EHMT1	EHMT1	214.25	0	45	0	0.73126411	FALSE	1	EHMT1	91098	0.08566364
791777	taxon:9606	2.48069954	5.35E-05	166938	1902	RNA polymerase I subunit B	gene	biological_process-&-1&-GO:0009303-&&-rRNA transcription-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0017126-&&-nucleologenesis-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0007566-&&-embryo implantation-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0032549-&&-ribonucleoside binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001054-&&-RNA polymerase I activity-%%-GO:0005515-&&-protein binding	G:9606:POLR1B			KEGG-&-1&-hsa03020-&&-RNA polymerase	POLR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR1B	0.4031121	0.16913319	46	4	FALSE	POLR1B	POLR1B	191.7954546	0	45	0	0.75321674	FALSE	1	POLR1B	105666	0.05817272
791781	taxon:9606	2.74271309	2.64E-05	166894	1902	mediator complex subunit 10	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0070847-&&-core mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016592-&&-mediator complex|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:MED10				MED10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED10	0.36460248	0.42028986	46	4	FALSE	MED10	MED10	82.82608696	0	46	0	0.70954782	FALSE	0	MED10	38856	0.0482979
791982	taxon:9606	2.65133134	6.58E-05	182773	1902	amyloid beta precursor like protein 1	gene	biological_process-&-1&-GO:0071874-&&-cellular response to norepinephrine stimulus-%%-GO:0006915-&&-apoptotic process-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:0006897-&&-endocytosis-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007399-&&-nervous system development-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0031694-&&-alpha-2A adrenergic receptor binding-%%-GO:0031695-&&-alpha-2B adrenergic receptor binding-%%-GO:0031696-&&-alpha-2C adrenergic receptor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:APLP1				APLP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APLP1	0.377169	0.12156448	46	4	FALSE	APLP1	APLP1	102.6590909	0	45	0	0.72477811	FALSE	1	APLP1	98934	0.04593269
792034	taxon:9606	2.66031196	2.09E-04	182705	1902	bone morphogenetic protein receptor type 1A	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0061626-&&-pharyngeal arch artery morphogenesis-%%-GO:0060914-&&-heart formation-%%-GO:0009950-&&-dorsal/ventral axis specification-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0003272-&&-endocardial cushion formation-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0060391-&&-positive regulation of SMAD protein import into nucleus-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:2000772-&&-regulation of cellular senescence-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1905285-&&-fibrous ring of heart morphogenesis-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0048378-&&-regulation of lateral mesodermal cell fate specification-%%-GO:0048589-&&-developmental growth-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0003186-&&-tricuspid valve morphogenesis-%%-GO:0001880-&&-Mullerian duct regression-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0001756-&&-somitogenesis-%%-GO:0010665-&&-regulation of cardiac muscle cell apoptotic process-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0048568-&&-embryonic organ development-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0048352-&&-paraxial mesoderm structural organization-%%-GO:0007398-&&-ectoderm development-%%-GO:0021983-&&-pituitary gland development-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0021998-&&-neural plate mediolateral regionalization-%%-GO:0006955-&&-immune response-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0014032-&&-neural crest cell development-%%-GO:1904414-&&-positive regulation of cardiac ventricle development-%%-GO:0035137-&&-hindlimb morphogenesis-%%-GO:0048368-&&-lateral mesoderm development-%%-GO:0061312-&&-BMP signaling pathway involved in heart development-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0060021-&&-palate development-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0048382-&&-mesendoderm development-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0001707-&&-mesoderm formation-%%-GO:1905292-&&-regulation of neural crest cell differentiation-%%-GO:0060043-&&-regulation of cardiac muscle cell proliferation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0043025-&&-neuronal cell body-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030425-&&-dendrite-%%-GO:1990712-&&-HFE-transferrin receptor complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0098821-&&-BMP receptor activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0046332-&&-SMAD binding	G:9606:BMPR1A			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	BMPR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMPR1A	0.37589577	0.06976744	46	4	FALSE	BMPR1A	BMPR1A	81.06818182	0	45	0	0.72328134	FALSE	1	BMPR1A	198832	0.03753428
792044	taxon:9606	2.70710572	6.04E-05	182694	1902	forkhead box L2	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046881-&&-positive regulation of follicle-stimulating hormone secretion-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0007338-&&-single fertilization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033686-&&-positive regulation of luteinizing hormone secretion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0042703-&&-menstruation-%%-GO:0060014-&&-granulosa cell differentiation-%%-GO:0060065-&&-uterus development-%%-GO:0001555-&&-oocyte growth-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0002074-&&-extraocular skeletal muscle development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0019101-&&-female somatic sex determination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043028-&&-cysteine-type endopeptidase regulator activity involved in apoptotic process-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:FOXL2	FOXL2	TRUE		FOXL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXL2	0.36939821	0.02222222	46	5	FALSE	FOXL2	FOXL2	77.30434783	0	46	0	0.71548238	FALSE	0	FOXL2	82974	0.04070183
792057	taxon:9606	2.43075469	4.89E-05	182677	1902	Kruppel like factor 5	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060576-&&-intestinal epithelial cell development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032534-&&-regulation of microvillus assembly-%%-GO:0030033-&&-microvillus assembly-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0001525-&&-angiogenesis-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:KLF5				KLF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF5	0.41139487	0.26280193	46	4	FALSE	KLF5	KLF5	219.1521739	0	46	0	0.76154089	FALSE	0	KLF5	111990	0.06077431
792447	taxon:9606	2.56278557	4.33E-04	182005	1902	cathepsin B	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0006508-&&-proteolysis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0046697-&&-decidualization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0042470-&&-melanosome-%%-GO:0036021-&&-endolysosome lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005730-&&-nucleolus-%%-GO:0005764-&&-lysosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005518-&&-collagen binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0043394-&&-proteoglycan binding	G:9606:CTSB			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04140-&&-Autophagy - animal-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04142-&&-Lysosome	CTSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSB	0.39020042	0.04439746	46	4	FALSE	CTSB	CTSB	101.0454546	0	45	0	0.73953574	FALSE	1	CTSB	444850	0.03656987
792461	taxon:9606	2.52276666	9.83E-05	181977	1902	CYLD lysine 63 deubiquitinase	gene	biological_process-&-1&-GO:1903829-&&-positive regulation of cellular protein localization-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1901026-&&-ripoptosome assembly involved in necroptotic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043369-&&-CD4-positive or CD8-positive, alpha-beta T cell lineage commitment-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:2001242-&&-regulation of intrinsic apoptotic signaling pathway-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0070266-&&-necroptotic process-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:1990108-&&-protein linear deubiquitination-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0050862-&&-positive regulation of T cell receptor signaling pathway-%%-GO:0045581-&&-negative regulation of T cell differentiation-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0045087-&&-innate immune response-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:0097542-&&-ciliary tip-%%-GO:0005813-&&-centrosome-%%-GO:0030496-&&-midbody-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity	G:9606:CYLD			KEGG-&-1&-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	CYLD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYLD	0.39639021	0.16328502	46	4	FALSE	CYLD	CYLD	148.6956522	0	46	0	0.74620556	FALSE	0	CYLD	140186	0.04903493
792536	taxon:9606	2.50275721	5.74E-05	181837	1902	cysteinyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006423-&&-cysteinyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0000049-&&-tRNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004817-&&-cysteine-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:CARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	CARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARS	0.39955933	0.24251208	46	4	FALSE	CARS	CARS	192.2173913	0	46	0	0.74954047	FALSE	0	CARS	133060	0.06108516
792546	taxon:9606	2.52954152	6.94E-05	181831	1902	caspase 6	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006508-&&-proteolysis-%%-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process	G:9606:CASP6			KEGG-&-1&-hsa04210-&&-Apoptosis	CASP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP6	0.39532856	0.13002114	46	4	FALSE	CASP6	CASP6	130.75	0	45	0	0.74507641	FALSE	1	CASP6	109062	0.04384641
792575	taxon:9606	2.53537104	1.45E-04	181791	1902	cyclin D3	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CCND3			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05203-&&-Viral carcinogenesis	CCND3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCND3	0.39441959	0.09661836	46	4	FALSE	CCND3	CCND3	124.826087	0	46	0	0.74410483	FALSE	0	CCND3	168210	0.04251406
792727	taxon:9606	2.72616984	1.44E-04	181491	1902	discs large MAGUK scaffold protein 3	gene	biological_process-&-1&-GO:0043113-&&-receptor clustering-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0097120-&&-receptor localization to synapse-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043198-&&-dendritic shaft-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0030426-&&-growth cone-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019900-&&-kinase binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:DLG3			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	DLG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLG3	0.366815	0.06666667	46	4	FALSE	DLG3	DLG3	73.15217391	0	46	0	0.71230503	FALSE	0	DLG3	156168	0.04153572
793085	taxon:9606	2.46951316	1.20E-04	180771	1902	ferritin heavy chain 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006880-&&-intracellular sequestering of iron ion-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0097286-&&-iron ion import-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0044754-&&-autolysosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0008043-&&-intracellular ferritin complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004322-&&-ferroxidase activity-%%-GO:0008199-&&-ferric iron binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding	G:9606:FTH1			KEGG-&-1&-hsa04978-&&-Mineral absorption-%%-hsa04217-&&-Necroptosis-%%-hsa04216-&&-Ferroptosis	FTH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTH1	0.40493811	0.06765328	46	4	FALSE	FTH1	FTH1	150.4090909	0	45	0	0.75508114	FALSE	1	FTH1	176942	0.0449042
787157	taxon:9606	2.58311013	9.31E-05	179960	1902	LIM domain containing preferred translocation partner in lipoma	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:LPP	LPP	TRUE		LPP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPP	0.38713022	0.11313131	45	4	FALSE	LPP	LPP	115.0222222	0	45	0	0.73614831	FALSE	0	LPP	120620	0.04327309
787492	taxon:9606	2.74255554	2.47E-05	179346	1902	MLLT1, super elongation complex subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006469-&&-negative regulation of protein kinase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:MLLT1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	MLLT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLLT1	0.36462343	0.25858586	45	5	FALSE	MLLT1	MLLT1	152.7777778	0	45	0	0.70957408	FALSE	0	MLLT1	61232	0.08692848
787672	taxon:9606	2.49125571	7.44E-05	178973	1902	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0014829-&&-vascular smooth muscle contraction-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0006887-&&-exocytosis-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:PIK3C2A			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PIK3C2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3C2A	0.401404	0.17878788	45	4	FALSE	PIK3C2A	PIK3C2A	172.0444444	0	45	0	0.75145738	FALSE	0	PIK3C2A	131716	0.05326038
787717	taxon:9606	2.50322987	4.97E-05	178889	1902	PMS1 homolog 1, mismatch repair system component	gene	biological_process-&-1&-GO:0006298-&&-mismatch repair-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0032389-&&-MutLalpha complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0016887-&&-ATPase activity	G:9606:PMS1				PMS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMS1	0.39948389	0.13953488	45	4	FALSE	PMS1	PMS1	173.0697674	0	44	0	0.74946169	FALSE	1	PMS1	84002	0.0546677
787735	taxon:9606	2.61982039	6.20E-05	178859	1902	RNA polymerase II subunit D	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0034402-&&-recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031990-&&-mRNA export from nucleus in response to heat stress-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0010467-&&-gene expression-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0000166-&&-nucleotide binding	G:9606:POLR2D			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2D	0.38170556	0.22812846	45	4	FALSE	POLR2D	POLR2D	114.627907	0	44	0	0.73002994	FALSE	1	POLR2D	88344	0.04706579
787740	taxon:9606	2.57712305	5.22E-05	178855	1902	RNA polymerase II subunit H	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity	G:9606:POLR2H			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2H	0.38802959	0.25027685	45	4	FALSE	POLR2H	POLR2H	138.2790698	0	44	0	0.73714616	FALSE	1	POLR2H	91478	0.05105458
787752	taxon:9606	2.50921695	3.25E-05	162452	1902	heterogeneous nuclear ribonucleoprotein U like 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:HNRNPUL2				HNRNPUL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPUL2	0.3985307	0.16363636	45	4	FALSE	HNRNPUL2	HNRNPUL2	223.1333333	0	45	0	0.74846384	FALSE	0	HNRNPUL2	99622	0.07157167
787766	taxon:9606	2.33685206	6.92E-05	178817	1902	peptidylprolyl isomerase D	gene	biological_process-&-1&-GO:0019076-&&-viral release from host cell-%%-GO:0006915-&&-apoptotic process-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0015031-&&-protein transport-%%-GO:0034389-&&-lipid particle organization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0006457-&&-protein folding-%%-GO:0006461-&&-protein complex assembly-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0071492-&&-cellular response to UV-A-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0016018-&&-cyclosporin A binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0030544-&&-Hsp70 protein binding	G:9606:PPID			KEGG-&-1&-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis	PPID	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPID	0.42792611	0.17777778	45	4	FALSE	PPID	PPID	245.2888889	0	45	0	0.77719132	FALSE	0	PPID	153662	0.05864817
787933	taxon:9606	2.51882779	1.04E-04	178561	1902	oxysterol binding protein	gene	biological_process-&-1&-GO:0044128-&&-positive regulation of growth of symbiont in host-%%-GO:0015918-&&-sterol transport-%%-GO:0006699-&&-bile acid biosynthetic process|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015248-&&-sterol transporter activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008142-&&-oxysterol binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding	G:9606:OSBP				OSBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSBP	0.39701007	0.21313131	45	4	FALSE	OSBP	OSBP	200.4444444	0	45	0	0.74686203	FALSE	0	OSBP	182972	0.06546154
788410	taxon:9606	2.50102411	1.11E-04	177723	1902	syntaxin binding protein 1	gene	biological_process-&-1&-GO:0002576-&&-platelet degranulation-%%-GO:0014047-&&-glutamate secretion-%%-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0015031-&&-protein transport-%%-GO:0070527-&&-platelet aggregation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0099525-&&-presynaptic dense core vesicle exocytosis-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:0031630-&&-regulation of synaptic vesicle fusion to presynaptic membrane-%%-GO:0007412-&&-axon target recognition-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0010807-&&-regulation of synaptic vesicle priming-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0032229-&&-negative regulation of synaptic transmission, GABAergic-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0035542-&&-regulation of SNARE complex assembly-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031091-&&-platelet alpha granule-%%-GO:0043195-&&-terminal bouton-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0048787-&&-presynaptic active zone membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0019901-&&-protein kinase binding	G:9606:STXBP1			KEGG-&-1&-hsa04721-&&-Synaptic vesicle cycle	STXBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STXBP1	0.39983621	0.07070707	45	4	FALSE	STXBP1	STXBP1	123.6888889	0	45	0	0.74982932	FALSE	0	STXBP1	144742	0.03926138
788456	taxon:9606	2.72900583	6.68E-05	161248	1902	centrosomal protein 57 like 1	gene	biological_process-&-1&-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0043015-&&-gamma-tubulin binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP57L1				CEP57L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP57L1	0.36643381	0.10741971	45	4	FALSE	CEP57L1	CEP57L1	74.1627907	0	44	0	0.71183236	FALSE	1	CEP57L1	80598	0.0419871
788530	taxon:9606	2.48353553	7.00E-05	177492	1902	TIA1 cytotoxic granule associated RNA binding protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0048024-&&-regulation of mRNA splicing, via spliceosome-%%-GO:1904037-&&-positive regulation of epithelial cell apoptotic process-%%-GO:0042036-&&-negative regulation of cytokine biosynthetic process-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097165-&&-nuclear stress granule-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:TIA1				TIA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIA1	0.40265178	0.18080808	45	4	FALSE	TIA1	TIA1	246.2444444	0	45	0	0.75274408	FALSE	0	TIA1	143126	0.0752445
788699	taxon:9606	2.56688199	1.06E-04	177162	1902	troponin T1, slow skeletal type	gene	biological_process-&-1&-GO:0030049-&&-muscle filament sliding-%%-GO:0031444-&&-slow-twitch skeletal muscle fiber contraction-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0014883-&&-transition between fast and slow fiber-%%-GO:0045932-&&-negative regulation of muscle contraction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005861-&&-troponin complex|molecular_function-&-1&-GO:0005523-&&-tropomyosin binding-%%-GO:0031014-&&-troponin T binding-%%-GO:0005515-&&-protein binding	G:9606:TNNT1				TNNT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNNT1	0.38957771	0.05869324	45	4	FALSE	TNNT1	TNNT1	120.8139535	0	44	0	0.738853	FALSE	1	TNNT1	124908	0.04379155
788785	taxon:9606	2.80715299	1.18E-05	176911	1902	bromodomain and PHD finger containing 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070776-&&-MOZ/MORF histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:BRPF1				BRPF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRPF1	0.35623281	0.34545455	45	4	FALSE	BRPF1	BRPF1	198.1555556	0	45	0	0.69880784	FALSE	0	BRPF1	37922	0.14157732
788874	taxon:9606	2.47502757	6.42E-05	176712	1902	tryptophanyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006436-&&-tryptophanyl-tRNA aminoacylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0001525-&&-angiogenesis-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004830-&&-tryptophan-tRNA ligase activity-%%-GO:0005515-&&-protein binding	G:9606:WARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	WARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WARS	0.4040359	0.10852713	45	4	FALSE	WARS	WARS	161.1860465	0	44	0	0.75416207	FALSE	1	WARS	106786	0.04852139
788915	taxon:9606	2.45139436	8.89E-05	176606	1902	solute carrier family 25 member 11	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006810-&&-transport-%%-GO:0015742-&&-alpha-ketoglutarate transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0015367-&&-oxoglutarate:malate antiporter activity	G:9606:SLC25A11				SLC25A11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A11	0.4079311	0.07641196	45	4	FALSE	SLC25A11	SLC25A11	210.0697674	0	44	0	0.75810094	FALSE	1	SLC25A11	184100	0.0605201
788942	taxon:9606	2.51221049	4.34E-05	176553	1902	sorbin and SH3 domain containing 2	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:0007155-&&-cell adhesion-%%-GO:0007015-&&-actin filament organization-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0008307-&&-structural constituent of muscle	G:9606:SORBS2				SORBS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORBS2	0.39805582	0.19601329	45	4	FALSE	SORBS2	SORBS2	177.4186047	0	44	0	0.74796492	FALSE	1	SORBS2	90230	0.05717991
788953	taxon:9606	2.60359225	3.33E-05	176542	1902	gem nuclear organelle associated protein 2	gene	biological_process-&-1&-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing-%%-GO:0051170-&&-nuclear import-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0000245-&&-spliceosomal complex assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GEMIN2			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN2	0.38408472	0.20376523	45	4	FALSE	GEMIN2	GEMIN2	141.2325581	0	44	0	0.73273463	FALSE	1	GEMIN2	65256	0.05514509
788974	taxon:9606	2.56940287	1.07E-04	176493	1902	zinc finger protein 24	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042552-&&-myelination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF24				ZNF24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF24	0.38919549	0.06464646	45	4	FALSE	ZNF24	ZNF24	127.7555556	0	45	0	0.73843286	FALSE	0	ZNF24	138234	0.04659603
789041	taxon:9606	2.51993068	1.15E-04	176308	1902	cell division cycle 45	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0000076-&&-DNA replication checkpoint-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0000727-&&-double-strand break repair via break-induced replication-%%-GO:0006267-&&-pre-replicative complex assembly involved in nuclear cell cycle DNA replication-%%-GO:0031938-&&-regulation of chromatin silencing at telomere-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:1902977-&&-mitotic DNA replication preinitiation complex assembly|cellular_component-&-1&-GO:0031261-&&-DNA replication preinitiation complex-%%-GO:0005813-&&-centrosome-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005656-&&-nuclear pre-replicative complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0043138-&&-3'-5' DNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:CDC45			KEGG-&-1&-hsa04110-&&-Cell cycle	CDC45	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC45	0.39683631	0.24646465	45	4	FALSE	CDC45	CDC45	239.8	0	45	0	0.74667822	FALSE	0	CDC45	180220	0.07803819
789042	taxon:9606	2.60847645	5.61E-05	176311	1902	BRCA1 associated protein 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0061519-&&-macrophage homeostasis-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0035522-&&-monoubiquitinated histone H2A deubiquitination-%%-GO:0010035-&&-response to inorganic substance-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0001558-&&-regulation of cell growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035517-&&-PR-DUB complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:BAP1				BAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAP1	0.38336555	0.06969697	45	4	FALSE	BAP1	BAP1	118.6888889	0	45	0	0.73192059	FALSE	0	BAP1	87198	0.04752864
789143	taxon:9606	2.69434378	1.88E-05	176123	1902	TATA-box binding protein associated factor, RNA polymerase I subunit A	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006360-&&-transcription from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000120-&&-RNA polymerase I transcription factor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TAF1A				TAF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1A	0.37114789	0.45404208	45	4	FALSE	TAF1A	TAF1A	233.6976744	0	44	0	0.71760937	FALSE	1	TAF1A	58920	0.11511055
789178	taxon:9606	2.52654798	2.55E-05	176046	1902	histone cluster 2 H2A family member a3	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2AA3			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST2H2AA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2AA3	0.39579696	0.23535354	45	4	FALSE	HIST2H2AA3	HIST2H2AA3	256.2444444	0	45	0	0.74557534	FALSE	0	HIST2H2AA3	101058	0.08462357
789214	taxon:9606	2.73452025	7.54E-05	175987	1902	pirin	gene	biological_process-&-1&-GO:0030224-&&-monocyte differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008127-&&-quercetin 2,3-dioxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:PIR				PIR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIR	0.36569486	0.10505051	45	4	FALSE	PIR	PIR	74.37777778	0	45	0	0.71091329	FALSE	0	PIR	91688	0.04300328
789287	taxon:9606	2.61304553	9.55E-05	175826	1902	GRB2-related adaptor protein 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0016477-&&-cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:GRAP2			KEGG-&-1&-hsa04660-&&-T cell receptor signaling pathway	GRAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRAP2	0.38269521	0.1030303	45	4	FALSE	GRAP2	GRAP2	109.5111111	0	45	0	0.73115908	FALSE	0	GRAP2	127162	0.04458033
789298	taxon:9606	2.64140539	5.13E-05	175793	1902	mediator complex subunit 7	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0016604-&&-nuclear body-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED7				MED7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED7	0.37858634	0.34343434	45	5	FALSE	MED7	MED7	108.0444444	0	45	0	0.72643244	FALSE	0	MED7	79860	0.04694577
789403	taxon:9606	2.46730739	4.58E-05	175548	1902	thyroid hormone receptor interactor 12	gene	biological_process-&-1&-GO:2000780-&&-negative regulation of double-strand break repair-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1901315-&&-negative regulation of histone H2A K63-linked ubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0009790-&&-embryo development-%%-GO:0006281-&&-DNA repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TRIP12			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	TRIP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP12	0.40530013	0.09090909	45	4	FALSE	TRIP12	TRIP12	226.2666667	0	45	0	0.75544877	FALSE	0	TRIP12	122156	0.0669165
789410	taxon:9606	2.42555538	8.15E-05	175540	1902	general transcription factor IIIC subunit 3	gene	biological_process-&-1&-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0042797-&&-tRNA transcription from RNA polymerase III promoter-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0042791-&&-5S class rRNA transcription from RNA polymerase III type 1 promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000127-&&-transcription factor TFIIIC complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000995-&&-transcription factor activity, core RNA polymerase III binding-%%-GO:0005515-&&-protein binding	G:9606:GTF3C3				GTF3C3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF3C3	0.41227671	0.15656566	45	4	FALSE	GTF3C3	GTF3C3	220.1555556	0	45	0	0.76240744	FALSE	0	GTF3C3	161398	0.06055326
789551	taxon:9606	2.44745549	9.72E-05	175202	1902	ring finger protein 40	gene	biological_process-&-1&-GO:0033523-&&-histone H2B ubiquitination-%%-GO:0043434-&&-response to peptide hormone-%%-GO:1900364-&&-negative regulation of mRNA polyadenylation-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0010390-&&-histone monoubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2001168-&&-positive regulation of histone H2B ubiquitination-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0033503-&&-HULC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0043679-&&-axon terminus-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:RNF40				RNF40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF40	0.40858761	0.10077519	45	4	FALSE	RNF40	RNF40	167.5581395	0	44	0	0.75875742	FALSE	1	RNF40	151604	0.04766317
789586	taxon:9606	2.40349772	1.17E-04	175124	1902	ubiquitin associated protein 2 like	gene	biological_process-&-1&-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0061484-&&-hematopoietic stem cell homeostasis|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UBAP2L				UBAP2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBAP2L	0.41606031	0.13333333	45	4	FALSE	UBAP2L	UBAP2L	264.1333333	0	45	0	0.76608371	FALSE	0	UBAP2L	201328	0.0701686
789625	taxon:9606	2.61982039	3.19E-05	175035	1902	mediator complex subunit 6	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0070847-&&-core mediator complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001128-&&-RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:MED6				MED6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED6	0.38170556	0.39191919	45	4	FALSE	MED6	MED6	131.7777778	0	45	0	0.73002994	FALSE	0	MED6	71244	0.05413129
789696	taxon:9606	2.54939341	1.31E-04	174871	1902	amyloid beta precursor protein binding protein 2	gene	biological_process-&-1&-GO:0046907-&&-intracellular transport-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding	G:9606:APPBP2				APPBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APPBP2	0.39225017	0.03765227	45	4	FALSE	APPBP2	APPBP2	115.3953488	0	44	0	0.74176776	FALSE	1	APPBP2	159696	0.04047445
789733	taxon:9606	2.53836458	9.29E-05	174796	1902	target of myb1 like 1 membrane trafficking protein	gene	biological_process-&-1&-GO:0045839-&&-negative regulation of mitotic nuclear division-%%-GO:2000278-&&-regulation of DNA biosynthetic process-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome-%%-GO:0005795-&&-Golgi stack|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:TOM1L1				TOM1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOM1L1	0.39395444	0.12929293	45	4	FALSE	TOM1L1	TOM1L1	136.6666667	0	45	0	0.7436059	FALSE	0	TOM1L1	131668	0.04671683
789842	taxon:9606	2.51851268	1.24E-04	174529	1902	EH domain containing 1	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:2001137-&&-positive regulation of endocytic recycling-%%-GO:0061512-&&-protein localization to cilium-%%-GO:0007596-&&-blood coagulation-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0032456-&&-endocytic recycling-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0031175-&&-neuron projection development-%%-GO:0060271-&&-cilium assembly-%%-GO:0006897-&&-endocytosis-%%-GO:0042632-&&-cholesterol homeostasis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0020018-&&-ciliary pocket membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0045296-&&-cadherin binding	G:9606:EHD1			KEGG-&-1&-hsa04144-&&-Endocytosis	EHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHD1	0.39705974	0.10077519	45	4	FALSE	EHD1	EHD1	138	0	44	0	0.74691455	FALSE	1	EHD1	141634	0.04508951
790218	taxon:9606	2.43784465	7.73E-05	173605	1902	nucleoporin 205	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0034399-&&-nuclear periphery-%%-GO:0044611-&&-nuclear pore inner ring|molecular_function-&-1&-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005515-&&-protein binding	G:9606:NUP205			KEGG-&-1&-hsa03013-&&-RNA transport	NUP205	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP205	0.41019841	0.13030303	45	4	FALSE	NUP205	NUP205	268.5333333	0	45	0	0.76035922	FALSE	0	NUP205	204410	0.07561441
790241	taxon:9606	2.565464	6.48E-05	173542	1902	SIN3 transcription regulator family member B	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0016575-&&-histone deacetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0030849-&&-autosome-%%-GO:0000806-&&-Y chromosome-%%-GO:0000805-&&-X chromosome-%%-GO:0001741-&&-XY body-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004407-&&-histone deacetylase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity	G:9606:SIN3B				SIN3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIN3B	0.38979304	0.2040404	45	4	FALSE	SIN3B	SIN3B	148.1111111	0	45	0	0.73908933	FALSE	0	SIN3B	107644	0.05294562
790257	taxon:9606	2.64802269	1.57E-04	173492	1902	tensin 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0001822-&&-kidney development-%%-GO:0048871-&&-multicellular organismal homeostasis-%%-GO:0014850-&&-response to muscle activity-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0032963-&&-collagen metabolic process-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:TNS2				TNS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNS2	0.37764027	0.03737374	45	4	FALSE	TNS2	TNS2	88.51111111	0	45	0	0.72532955	FALSE	0	TNS2	171154	0.0394708
790356	taxon:9606	2.46730739	2.40E-04	173225	1902	scribbled planar cell polarity protein	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0071896-&&-protein localization to adherens junction-%%-GO:0035089-&&-establishment of apical/basal cell polarity-%%-GO:0060561-&&-apoptotic process involved in morphogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0097120-&&-receptor localization to synapse-%%-GO:0016080-&&-synaptic vesicle targeting-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0001843-&&-neural tube closure-%%-GO:0042060-&&-wound healing-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:0016032-&&-viral process-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0008105-&&-asymmetric protein localization-%%-GO:0098968-&&-neurotransmitter receptor transport postsynaptic membrane to endosome-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0043113-&&-receptor clustering-%%-GO:0098887-&&-neurotransmitter receptor transport, endosome to postsynaptic membrane-%%-GO:0060603-&&-mammary gland duct morphogenesis-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0016477-&&-cell migration-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0021747-&&-cochlear nucleus development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034750-&&-Scrib-APC-beta-catenin complex-%%-GO:0030027-&&-lamellipodium-%%-GO:0031252-&&-cell leading edge-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005911-&&-cell-cell junction-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0035748-&&-myelin sheath abaxonal region|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:SCRIB			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	SCRIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCRIB	0.40530013	0.05858586	45	4	FALSE	SCRIB	SCRIB	193.2444444	0	45	0	0.75544877	FALSE	0	SCRIB	305876	0.05741953
790678	taxon:9606	2.45738144	7.38E-05	171489	1902	drosha ribonuclease III	gene	biological_process-&-1&-GO:0031053-&&-primary miRNA processing-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0045589-&&-regulation of regulatory T cell differentiation-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:2000628-&&-regulation of miRNA metabolic process-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0016075-&&-rRNA catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0070877-&&-microprocessor complex|molecular_function-&-1&-GO:0004525-&&-ribonuclease III activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0070878-&&-primary miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:DROSHA			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa05205-&&-Proteoglycans in cancer	DROSHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DROSHA	0.40693723	0.13636364	45	4	FALSE	DROSHA	DROSHA	185.1333333	0	45	0	0.75710309	FALSE	0	DROSHA	122568	0.05393309
790702	taxon:9606	2.51362849	7.34E-05	171424	1902	striatin 4	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043197-&&-dendritic spine-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005515-&&-protein binding	G:9606:STRN4				STRN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRN4	0.39783126	0.14545455	45	4	FALSE	STRN4	STRN4	135.9777778	0	45	0	0.74772859	FALSE	0	STRN4	114498	0.04420588
790759	taxon:9606	2.6201355	5.40E-05	171308	1902	lymphoid enhancer binding factor 1	gene	biological_process-&-1&-GO:0030509-&&-BMP signaling pathway-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071864-&&-positive regulation of cell proliferation in bone marrow-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0045843-&&-negative regulation of striated muscle tissue development-%%-GO:0061153-&&-trachea gland development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0060033-&&-anatomical structure regression-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0030854-&&-positive regulation of granulocyte differentiation-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001756-&&-somitogenesis-%%-GO:0021873-&&-forebrain neuroblast division-%%-GO:0033153-&&-T cell receptor V(D)J recombination-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0043586-&&-tongue development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0022407-&&-regulation of cell-cell adhesion-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0050909-&&-sensory perception of taste-%%-GO:0021879-&&-forebrain neuron differentiation-%%-GO:0071866-&&-negative regulation of apoptotic process in bone marrow-%%-GO:0060561-&&-apoptotic process involved in morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048341-&&-paraxial mesoderm formation-%%-GO:0060710-&&-chorio-allantoic fusion-%%-GO:0021861-&&-forebrain radial glial cell differentiation-%%-GO:0046632-&&-alpha-beta T cell differentiation-%%-GO:0071895-&&-odontoblast differentiation-%%-GO:0048069-&&-eye pigmentation-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0032713-&&-negative regulation of interleukin-4 production-%%-GO:0045063-&&-T-helper 1 cell differentiation-%%-GO:0048747-&&-muscle fiber development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030879-&&-mammary gland development-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0032696-&&-negative regulation of interleukin-13 production-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0060021-&&-palate development-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0030223-&&-neutrophil differentiation-%%-GO:1902262-&&-apoptotic process involved in blood vessel morphogenesis-%%-GO:0032714-&&-negative regulation of interleukin-5 production-%%-GO:0071899-&&-negative regulation of estrogen receptor binding-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0060325-&&-face morphogenesis-%%-GO:0021854-&&-hypothalamus development|cellular_component-&-1&-GO:1990907-&&-beta-catenin-TCF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042393-&&-histone binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0003682-&&-chromatin binding	G:9606:LEF1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05216-&&-Thyroid cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	LEF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LEF1	0.38165965	0.11818182	45	4	FALSE	LEF1	LEF1	124.0888889	0	45	0	0.72997742	FALSE	0	LEF1	88548	0.05057096
790795	taxon:9606	2.52654798	2.55E-05	154797	1902	histone cluster 2 H2A family member a4	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2AA4			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST2H2AA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2AA4	0.39579696	0.23535354	45	4	FALSE	HIST2H2AA4	HIST2H2AA4	256.2444444	0	45	0	0.74557534	FALSE	0	HIST2H2AA4	101058	0.08462357
790925	taxon:9606	2.46084764	1.04E-04	170689	1902	golgi to ER traffic protein 4	gene	biological_process-&-1&-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0071816-&&-tail-anchored membrane protein insertion into ER membrane-%%-GO:0006810-&&-transport-%%-GO:1904378-&&-maintenance of unfolded protein involved in ERAD pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0071818-&&-BAT3 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding	G:9606:GET4				GET4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GET4	0.40636404	0.12929293	45	4	FALSE	GET4	GET4	164.5333333	0	45	0	0.75652539	FALSE	0	GET4	153854	0.04819591
790954	taxon:9606	2.47045848	6.99E-05	170616	1902	LUC7 like 3 pre-mRNA splicing factor	gene	biological_process-&-1&-GO:0006376-&&-mRNA splice site selection-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003729-&&-mRNA binding	G:9606:LUC7L3				LUC7L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUC7L3	0.40478316	0.22369878	45	4	FALSE	LUC7L3	LUC7L3	262.3023256	0	44	0	0.75492359	FALSE	1	LUC7L3	128722	0.07827838
791127	taxon:9606	2.48117221	2.92E-05	169948	1902	regulator of chromosome condensation 2	gene	biological_process-&-1&-GO:0051987-&&-positive regulation of attachment of spindle microtubules to kinetochore-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0051301-&&-cell division-%%-GO:0072356-&&-chromosome passenger complex localization to kinetochore-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0045184-&&-establishment of protein localization-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:1900027-&&-regulation of ruffle assembly-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0030334-&&-regulation of cell migration|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0034506-&&-chromosome, centromeric core domain-%%-GO:0005874-&&-microtubule-%%-GO:0005829-&&-cytosol-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0048365-&&-Rac GTPase binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019901-&&-protein kinase binding	G:9606:RCC2				RCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCC2	0.40303531	0.14141414	45	4	FALSE	RCC2	RCC2	248.6888889	0	45	0	0.75313797	FALSE	0	RCC2	94304	0.07578313
791306	taxon:9606	2.46053254	6.50E-05	169274	1902	partner of NOB1 homolog	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:PNO1				PNO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNO1	0.40641609	0.29494949	45	4	FALSE	PNO1	PNO1	224.3333333	0	45	0	0.75657791	FALSE	0	PNO1	112832	0.06565183
791985	taxon:9606	2.56877265	1.16E-04	182774	1902	baculoviral IAP repeat containing 5	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016925-&&-protein sumoylation-%%-GO:0031503-&&-protein complex localization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000228-&&-nuclear chromosome-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0032133-&&-chromosome passenger complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0042802-&&-identical protein binding	G:9606:BIRC5	BIRC5	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05161-&&-Hepatitis B	BIRC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC5	0.38929097	0.11295681	45	4	FALSE	BIRC5	BIRC5	153.1395349	0	44	0	0.73853789	FALSE	1	BIRC5	169522	0.05551524
792842	taxon:9606	2.55900425	1.35E-04	181276	1902	epidermal growth factor receptor pathway substrate 8	gene	biological_process-&-1&-GO:0030832-&&-regulation of actin filament length-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0070358-&&-actin polymerization-dependent cell motility-%%-GO:0007165-&&-signal transduction-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0036336-&&-dendritic cell migration-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0008283-&&-cell proliferation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0010458-&&-exit from mitosis-%%-GO:0051017-&&-actin filament bundle assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0032420-&&-stereocilium-%%-GO:0005938-&&-cell cortex-%%-GO:0031982-&&-vesicle-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005903-&&-brush border-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0048365-&&-Rac GTPase binding	G:9606:EPS8				EPS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPS8	0.390777	0.05426357	45	5	FALSE	EPS8	EPS8	123.4651163	0	44	0	0.74016596	FALSE	1	EPS8	152558	0.04420775
793033	taxon:9606	2.64298094	8.40E-05	180861	1902	glutamate ionotropic receptor NMDA type subunit 1	gene	biological_process-&-1&-GO:0042391-&&-regulation of membrane potential-%%-GO:0018964-&&-propylene metabolic process-%%-GO:0001661-&&-conditioned taste aversion-%%-GO:0007616-&&-long-term memory-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0051963-&&-regulation of synapse assembly-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0001975-&&-response to amphetamine-%%-GO:0001967-&&-suckling behavior-%%-GO:0008542-&&-visual learning-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0035176-&&-social behavior-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0060179-&&-male mating behavior-%%-GO:0021586-&&-pons maturation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0043576-&&-regulation of respiratory gaseous exchange-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0060134-&&-prepulse inhibition-%%-GO:0000165-&&-MAPK cascade-%%-GO:0043278-&&-response to morphine-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0006812-&&-cation transport-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008355-&&-olfactory learning-%%-GO:0019233-&&-sensory perception of pain|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005886-&&-plasma membrane-%%-GO:0043083-&&-synaptic cleft-%%-GO:0098839-&&-postsynaptic density membrane-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030425-&&-dendrite-%%-GO:0030054-&&-cell junction-%%-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0043197-&&-dendritic spine-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0009986-&&-cell surface-%%-GO:0060076-&&-excitatory synapse|molecular_function-&-1&-GO:1904315-&&-transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016594-&&-glycine binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004972-&&-NMDA glutamate receptor activity-%%-GO:0016595-&&-glutamate binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005262-&&-calcium channel activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0042165-&&-neurotransmitter binding	G:9606:GRIN1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05030-&&-Cocaine addiction-%%-hsa05033-&&-Nicotine addiction-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05016-&&-Huntington disease-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIN1	0.37836066	0.10409745	45	4	FALSE	GRIN1	GRIN1	98.79069767	0	44	0	0.72616984	FALSE	1	GRIN1	109338	0.0435854
793257	taxon:9606	2.65716086	7.65E-05	164042	1902	kinesin light chain 3	gene	biological_process-&-1&-GO:0008088-&&-axo-dendritic transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0005871-&&-kinesin complex-%%-GO:0005874-&&-microtubule-%%-GO:0031514-&&-motile cilium|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding	G:9606:KLC3			KEGG-&-1&-hsa05132-&&-Salmonella infection	KLC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLC3	0.37634154	0.07198228	45	4	FALSE	KLC3	KLC3	103.7906977	0	44	0	0.72380652	FALSE	1	KLC3	102046	0.04713644
787048	taxon:9606	2.47061604	6.42E-04	180167	1902	insulin degrading enzyme	gene	biological_process-&-1&-GO:0010815-&&-bradykinin catabolic process-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0042447-&&-hormone catabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1901143-&&-insulin catabolic process-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0051289-&&-protein homotetramerization-%%-GO:1901142-&&-insulin metabolic process-%%-GO:0010992-&&-ubiquitin homeostasis|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0031597-&&-cytosolic proteasome complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0043559-&&-insulin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0031626-&&-beta-endorphin binding-%%-GO:0042277-&&-peptide binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043130-&&-ubiquitin binding	G:9606:IDE	IDE	TRUE	KEGG-&-1&-hsa05010-&&-Alzheimer disease	IDE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDE	0.40475735	0.08668076	44	4	FALSE	IDE	IDE	137.2272727	0	44	0	0.75489733	FALSE	0	IDE	649140	0.04100835
787239	taxon:9606	2.61288798	3.91E-05	179812	1902	interferon regulatory factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043374-&&-CD8-positive, alpha-beta T cell differentiation-%%-GO:0002819-&&-regulation of adaptive immune response-%%-GO:0045590-&&-negative regulation of regulatory T cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0007596-&&-blood coagulation-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:2000564-&&-regulation of CD8-positive, alpha-beta T cell proliferation-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0051607-&&-defense response to virus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0034124-&&-regulation of MyD88-dependent toll-like receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:IRF1	IRF1	TRUE	KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa05165-&&-Human papillomavirus infection	IRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF1	0.38271828	0.23784355	44	4	FALSE	IRF1	IRF1	211.0681818	0	44	0	0.73118534	FALSE	0	IRF1	94166	0.08521809
787452	taxon:9606	2.56688199	6.20E-05	179404	1902	mitogen-activated protein kinase kinase kinase 4	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0001890-&&-placenta development-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0000165-&&-MAPK cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0010225-&&-response to UV-C-%%-GO:0060718-&&-chorionic trophoblast cell differentiation-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0019100-&&-male germ-line sex determination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K4			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway-%%-hsa04912-&&-GnRH signaling pathway	MAP3K4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K4	0.38957771	0.07200929	44	4	FALSE	MAP3K4	MAP3K4	126	0	43	0	0.738853	FALSE	1	MAP3K4	100680	0.04580887
787482	taxon:9606	2.44934615	3.81E-05	179355	1902	marker of proliferation Ki-67	gene	biological_process-&-1&-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0008283-&&-cell proliferation-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0034605-&&-cellular response to heat-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:1902275-&&-regulation of chromatin organization-%%-GO:0007126-&&-meiotic nuclear division|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0000793-&&-condensed chromosome-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:MKI67				MKI67	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKI67	0.40827222	0.21138211	44	4	FALSE	MKI67	MKI67	261.5714286	0	43	0	0.75844231	FALSE	1	MKI67	96978	0.07498498
787928	taxon:9606	2.54671498	4.96E-05	178569	1902	origin recognition complex subunit 1	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005664-&&-nuclear origin of replication recognition complex-%%-GO:0000808-&&-origin recognition complex-%%-GO:0005730-&&-nucleolus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:ORC1	ORC1	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle	ORC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORC1	0.39266271	0.15433404	44	4	FALSE	ORC1	ORC1	145.1590909	0	44	0	0.74221417	FALSE	0	ORC1	89406	0.05001725
788325	taxon:9606	2.69528911	4.11E-05	177877	1902	SATB homeobox 1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043367-&&-CD4-positive, alpha-beta T cell differentiation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0008544-&&-epidermis development-%%-GO:0043374-&&-CD8-positive, alpha-beta T cell differentiation-%%-GO:0060004-&&-reflex-%%-GO:0016032-&&-viral process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050798-&&-activated T cell proliferation-%%-GO:0016571-&&-histone methylation-%%-GO:0006325-&&-chromatin organization|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SATB1				SATB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SATB1	0.37101771	0.16724739	44	4	FALSE	SATB1	SATB1	126.6428571	0	43	0	0.71745181	FALSE	1	SATB1	75936	0.06303358
788368	taxon:9606	2.61808729	5.73E-05	177794	1902	signal recognition particle 9	gene	biological_process-&-1&-GO:0045900-&&-negative regulation of translational elongation-%%-GO:0006616-&&-SRP-dependent cotranslational protein targeting to membrane, translocation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005785-&&-signal recognition particle receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005786-&&-signal recognition particle, endoplasmic reticulum targeting-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008312-&&-7S RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0005047-&&-signal recognition particle binding	G:9606:SRP9			KEGG-&-1&-hsa03060-&&-Protein export	SRP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRP9	0.38195824	0.11310782	44	4	FALSE	SRP9	SRP9	129.6590909	0	44	0	0.73031879	FALSE	0	SRP9	116172	0.0524327
788369	taxon:9606	2.44792816	6.92E-05	177789	1902	signal recognition particle 72	gene	biological_process-&-1&-GO:0042493-&&-response to drug-%%-GO:0006616-&&-SRP-dependent cotranslational protein targeting to membrane, translocation-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005786-&&-signal recognition particle, endoplasmic reticulum targeting|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008312-&&-7S RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0005047-&&-signal recognition particle binding	G:9606:SRP72			KEGG-&-1&-hsa03060-&&-Protein export	SRP72	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRP72	0.40850872	0.20295983	44	4	FALSE	SRP72	SRP72	264.2045455	0	44	0	0.75867864	FALSE	0	SRP72	148978	0.07523109
788464	taxon:9606	2.59981093	2.56E-05	177585	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0030182-&&-neuron differentiation-%%-GO:0007420-&&-brain development-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0090537-&&-CERF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0016589-&&-NURF complex|molecular_function-&-1&-GO:0036310-&&-annealing helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070615-&&-nucleosome-dependent ATPase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004386-&&-helicase activity-%%-GO:0031491-&&-nucleosome binding	G:9606:SMARCA1				SMARCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCA1	0.38464335	0.25792812	44	4	FALSE	SMARCA1	SMARCA1	208.4090909	0	44	0	0.73336484	FALSE	0	SMARCA1	89578	0.08084139
788555	taxon:9606	2.62486214	6.91E-05	177450	1902	surfeit 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:SURF2				SURF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SURF2	0.38097239	0.102537	44	4	FALSE	SURF2	SURF2	102.5681818	0	44	0	0.72918964	FALSE	0	SURF2	91862	0.04275954
788920	taxon:9606	2.55632582	9.36E-05	176599	1902	ubiquitously expressed prefoldin like chaperone	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0051297-&&-centrosome organization-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000930-&&-gamma-tubulin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0051015-&&-actin filament binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:UXT				UXT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UXT	0.39118644	0.10220674	44	5	FALSE	UXT	UXT	129.0952381	0	43	0	0.74061236	FALSE	1	UXT	154504	0.04577584
789171	taxon:9606	2.6069009	1.46E-04	176054	1902	N-myc and STAT interactor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0006954-&&-inflammatory response-%%-GO:0045355-&&-negative regulation of interferon-alpha biosynthetic process-%%-GO:0045358-&&-negative regulation of interferon-beta biosynthetic process-%%-GO:1902524-&&-positive regulation of protein K48-linked ubiquitination-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:NMI				NMI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NMI	0.38359724	0.07781649	44	4	FALSE	NMI	NMI	105.2142857	0	43	0	0.73218318	FALSE	1	NMI	138902	0.04196869
789226	taxon:9606	2.54718765	1.68E-04	175960	1902	calcium/calmodulin dependent serine protein kinase	gene	biological_process-&-1&-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0070509-&&-calcium ion import-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0090288-&&-negative regulation of cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005604-&&-basement membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005652-&&-nuclear lamina-%%-GO:0005730-&&-nucleolus-%%-GO:0060170-&&-ciliary membrane-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042043-&&-neurexin family protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:CASK				CASK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASK	0.39258984	0.05574913	44	4	FALSE	CASK	CASK	115.1190476	0	43	0	0.74213539	FALSE	1	CASK	175358	0.03996126
789366	taxon:9606	2.41547188	5.36E-05	175652	1902	Rho/Rac guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0007015-&&-actin filament organization-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0071802-&&-negative regulation of podosome assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:1902219-&&-negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071474-&&-cellular hyperosmotic response-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0071225-&&-cellular response to muramyl dipeptide|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0043198-&&-dendritic shaft-%%-GO:0031982-&&-vesicle-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0002102-&&-podosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity-%%-GO:0008017-&&-microtubule binding	G:9606:ARHGEF2			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04530-&&-Tight junction	ARHGEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF2	0.41399778	0.19027484	44	4	FALSE	ARHGEF2	ARHGEF2	252.75	0	44	0	0.76408802	FALSE	0	ARHGEF2	127166	0.0680594
789400	taxon:9606	2.50102411	9.90E-05	175559	1902	suppressor of cytokine signaling 6	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0050868-&&-negative regulation of T cell activation-%%-GO:0040008-&&-regulation of growth-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007259-&&-JAK-STAT cascade|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:SOCS6			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS6	0.39983621	0.11205074	44	4	FALSE	SOCS6	SOCS6	146.7727273	0	44	0	0.74982932	FALSE	0	SOCS6	154396	0.0464405
789448	taxon:9606	2.64376871	3.03E-05	175446	1902	eukaryotic translation elongation factor 1 epsilon 1	gene	biological_process-&-1&-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EEF1E1				EEF1E1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF1E1	0.37824791	0.28646934	44	4	FALSE	EEF1E1	EEF1E1	141.3409091	0	44	0	0.72603855	FALSE	0	EEF1E1	50346	0.06140611
789521	taxon:9606	2.44383173	1.51E-04	175268	1902	dynamin 1 like	gene	biological_process-&-1&-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0060047-&&-heart contraction-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0032459-&&-regulation of protein oligomerization-%%-GO:1903578-&&-regulation of ATP metabolic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0016559-&&-peroxisome fission-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0090650-&&-cellular response to oxygen-glucose deprivation-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0051289-&&-protein homotetramerization-%%-GO:1900063-&&-regulation of peroxisome organization-%%-GO:0090149-&&-mitochondrial membrane fission-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051259-&&-protein oligomerization-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:1904579-&&-cellular response to thapsigargin-%%-GO:1990910-&&-response to hypobaric hypoxia-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0061025-&&-membrane fusion-%%-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0006897-&&-endocytosis-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0070266-&&-necroptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:1905395-&&-response to flavonoid-%%-GO:0048312-&&-intracellular distribution of mitochondria|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0043234-&&-protein complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005777-&&-peroxisome-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0099073-&&-mitochondrion-derived vesicle|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0008289-&&-lipid binding-%%-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding	G:9606:DNM1L			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	DNM1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM1L	0.40919348	0.07897793	44	4	FALSE	DNM1L	DNM1L	180.1190476	0	43	0	0.75936138	FALSE	1	DNM1L	221240	0.05106579
789540	taxon:9606	2.49519458	7.90E-05	175229	1902	centriolar coiled-coil protein 110	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:1902018-&&-negative regulation of cilium assembly-%%-GO:0032053-&&-ciliary basal body organization-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0051298-&&-centrosome duplication-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCP110				CCP110	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCP110	0.40077035	0.13636364	44	4	FALSE	CCP110	CCP110	161.5454546	0	44	0	0.7508009	FALSE	0	CCP110	136436	0.0503743
789622	taxon:9606	2.47613046	1.35E-04	175037	1902	SCO2, cytochrome c oxidase assembly protein	gene	biological_process-&-1&-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0008535-&&-respiratory chain complex IV assembly-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006825-&&-copper ion transport-%%-GO:0001654-&&-eye development-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0030016-&&-myofibril|molecular_function-&-1&-GO:0005507-&&-copper ion binding-%%-GO:0005515-&&-protein binding	G:9606:SCO2			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer	SCO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCO2	0.40385594	0.09291521	44	4	FALSE	SCO2	SCO2	149.6190476	0	43	0	0.75397826	FALSE	1	SCO2	173126	0.04516046
789782	taxon:9606	2.587049	8.76E-05	174690	1902	ring finger protein 41	gene	biological_process-&-1&-GO:1901525-&&-negative regulation of macromitophagy-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0045619-&&-regulation of lymphocyte differentiation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006914-&&-autophagy-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045637-&&-regulation of myeloid cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031386-&&-protein tag-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005135-&&-interleukin-3 receptor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005128-&&-erythropoietin receptor binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0016881-&&-acid-amino acid ligase activity	G:9606:RNF41			KEGG-&-1&-hsa04144-&&-Endocytosis	RNF41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF41	0.3865408	0.029036	44	4	FALSE	RNF41	RNF41	103.8095238	0	43	0	0.73549183	FALSE	1	RNF41	120620	0.03951581
789814	taxon:9606	2.53442571	1.93E-04	174599	1902	progesterone receptor membrane component 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0020037-&&-heme binding-%%-GO:0005496-&&-steroid binding-%%-GO:0005515-&&-protein binding	G:9606:PGRMC1	PGRMC1	TRUE		PGRMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGRMC1	0.3945667	0.1205074	44	4	FALSE	PGRMC1	PGRMC1	197.0454546	0	44	0	0.74426238	FALSE	0	PGRMC1	265254	0.0666359
789829	taxon:9606	2.51331338	4.80E-05	174548	1902	poly(A) polymerase alpha	gene	biological_process-&-1&-GO:0043631-&&-RNA polyadenylation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0031440-&&-regulation of mRNA 3'-end processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004652-&&-polynucleotide adenylyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PAPOLA			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	PAPOLA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAPOLA	0.39788114	0.1205074	44	4	FALSE	PAPOLA	PAPOLA	155.1363636	0	44	0	0.7477811	FALSE	0	PAPOLA	86236	0.04998828
789843	taxon:9606	2.44099575	8.05E-05	174528	1902	AFG3 like matrix AAA peptidase subunit 2	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0051560-&&-mitochondrial calcium ion homeostasis-%%-GO:0006508-&&-proteolysis-%%-GO:0034982-&&-mitochondrial protein processing-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0048747-&&-muscle fiber development-%%-GO:0042407-&&-cristae formation-%%-GO:0021675-&&-nerve development-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0042552-&&-myelination-%%-GO:0060013-&&-righting reflex-%%-GO:0007409-&&-axonogenesis-%%-GO:0036444-&&-mitochondrial calcium uptake|cellular_component-&-1&-GO:0005745-&&-m-AAA complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:AFG3L2				AFG3L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AFG3L2	0.40966888	0.17758985	44	4	FALSE	AFG3L2	AFG3L2	191.6363636	0	44	0	0.75983404	FALSE	0	AFG3L2	162206	0.05419828
789941	taxon:9606	2.56073736	9.92E-05	174293	1902	nestin	gene	biological_process-&-1&-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0007420-&&-brain development-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0072089-&&-stem cell proliferation-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0007417-&&-central nervous system development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0048858-&&-cell projection morphogenesis-%%-GO:0030844-&&-positive regulation of intermediate filament depolymerization-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005882-&&-intermediate filament-%%-GO:0005737-&&-cytoplasm-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005198-&&-structural molecule activity-%%-GO:0019215-&&-intermediate filament binding	G:9606:NES				NES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NES	0.39051252	0.06448203	44	4	FALSE	NES	NES	129.1590909	0	44	0	0.73987711	FALSE	0	NES	119144	0.04609624
789951	taxon:9606	2.39845596	1.13E-04	174261	1902	septin 9	gene	biological_process-&-1&-GO:1902857-&&-positive regulation of non-motile cilium assembly-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0097730-&&-non-motile cilium-%%-GO:0001725-&&-stress fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0031105-&&-septin complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005930-&&-axoneme-%%-GO:0005874-&&-microtubule-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:SEPT9			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT9	0.4169349	0.14270613	44	4	FALSE	SEPT9	SEPT9	222.9318182	0	44	0	0.76692401	FALSE	0	SEPT9	176376	0.05870663
790283	taxon:9606	2.50291476	1.25E-04	173447	1902	RING1 and YY1 binding protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0035518-&&-histone H2A monoubiquitination-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031519-&&-PcG protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:RYBP				RYBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RYBP	0.39953418	0.18287526	44	4	FALSE	RYBP	RYBP	160.9318182	0	44	0	0.74951421	FALSE	0	RYBP	158594	0.05093845
790302	taxon:9606	2.6152513	6.17E-05	173380	1902	thioredoxin 2	gene	biological_process-&-1&-GO:0014070-&&-response to organic cyclic compound-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007584-&&-response to nutrient-%%-GO:0009749-&&-response to glucose-%%-GO:0048678-&&-response to axon injury-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0042493-&&-response to drug-%%-GO:0009725-&&-response to hormone-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006662-&&-glycerol ether metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0008113-&&-peptide-methionine (S)-S-oxide reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0033743-&&-peptide-methionine (R)-S-oxide reductase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:TXN2			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway	TXN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXN2	0.38237243	0.06271777	44	4	FALSE	TXN2	TXN2	114.0238095	0	43	0	0.73079145	FALSE	1	TXN2	88330	0.04662414
790351	taxon:9606	2.63100677	5.34E-06	173250	1902	l(3)mbt-like 1 (Drosophila)	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045652-&&-regulation of megakaryocyte differentiation-%%-GO:0006325-&&-chromatin organization-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042393-&&-histone binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031493-&&-nucleosomal histone binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0032093-&&-SAM domain binding	G:9606:L3MBTL1				L3MBTL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-L3MBTL1	0.38008264	0.60743322	44	4	FALSE	L3MBTL1	L3MBTL1	263.7619048	0	43	0	0.72816554	FALSE	1	L3MBTL1	26108	0.11059199
790430	taxon:9606	2.61099732	6.38E-05	140236	1902	eukaryotic elongation factor 2 kinase	gene		G:9606:LOC101930123				LOC101930123	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC101930123	0.38299541	0.0782241	44	4	FALSE	LOC101930123	LOC101930123	109.2272727	0	44	0	0.73150045	FALSE	0	LOC101930123	101514	0.04406907
790536	taxon:9606	2.54608476	5.74E-05	172551	1902	zinc finger protein 638	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:ZNF638				ZNF638	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF638	0.3927599	0.11839323	44	4	FALSE	ZNF638	ZNF638	215.3636364	0	44	0	0.74231921	FALSE	0	ZNF638	132664	0.07441945
790674	taxon:9606	2.67039546	1.82E-05	171527	1902	ATPase family, AAA domain containing 2	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031936-&&-negative regulation of chromatin silencing-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0042393-&&-histone binding-%%-GO:0016887-&&-ATPase activity	G:9606:ATAD2				ATAD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD2	0.37447637	0.27378436	44	4	FALSE	ATAD2	ATAD2	248.8863636	0	44	0	0.72160076	FALSE	0	ATAD2	71030	0.11484303
790708	taxon:9606	2.61099732	6.38E-05	171413	1902	eukaryotic elongation factor 2 kinase	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:0006414-&&-translational elongation-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0031952-&&-regulation of protein autophosphorylation-%%-GO:0071454-&&-cellular response to anoxia-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1990637-&&-response to prolactin-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0071320-&&-cellular response to cAMP|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004686-&&-elongation factor-2 kinase activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004672-&&-protein kinase activity	G:9606:EEF2K			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	EEF2K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF2K	0.38299541	0.0782241	44	4	FALSE	EEF2K	EEF2K	109.2272727	0	44	0	0.73150045	FALSE	0	EEF2K	101514	0.04406907
790722	taxon:9606	2.61808729	5.73E-05	155001	1902	signal recognition particle 9 pseudogene 1	gene		G:9606:SRP9P1				SRP9P1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRP9P1	0.38195824	0.11310782	44	4	FALSE	SRP9P1	SRP9P1	129.6590909	0	44	0	0.73031879	FALSE	0	SRP9P1	116172	0.0524327
790998	taxon:9606	2.70143375	1.44E-04	170457	1902	dynein axonemal assembly factor 2	gene	biological_process-&-1&-GO:0071973-&&-bacterial-type flagellum-dependent cell motility-%%-GO:0070286-&&-axonemal dynein complex assembly-%%-GO:0060285-&&-cilium-dependent cell motility-%%-GO:0032526-&&-response to retinoic acid|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DNAAF2				DNAAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAAF2	0.3701738	0.03699789	44	5	FALSE	DNAAF2	DNAAF2	71.34090909	0	44	0	0.71642771	FALSE	0	DNAAF2	150534	0.03697175
791087	taxon:9606	2.55994958	8.79E-05	170105	1902	ubiquitin like modifier activating enzyme 6	gene	biological_process-&-1&-GO:0007612-&&-learning-%%-GO:0021766-&&-hippocampus development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007626-&&-locomotory behavior-%%-GO:0060996-&&-dendritic spine development-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0021764-&&-amygdala development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004839-&&-ubiquitin activating enzyme activity-%%-GO:0019780-&&-FAT10 activating enzyme activity	G:9606:UBA6			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBA6	0.39063269	0.09302326	44	4	FALSE	UBA6	UBA6	129.1590909	0	44	0	0.7400084	FALSE	0	UBA6	113062	0.04598064
791098	taxon:9606	2.7461793	4.16E-05	170058	1902	BRF2, RNA polymerase III transcription initiation factor subunit	gene	biological_process-&-1&-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0034599-&&-cellular response to oxidative stress|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001007-&&-transcription factor activity, RNA polymerase III transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001032-&&-RNA polymerase III type 3 promoter DNA binding	G:9606:BRF2				BRF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRF2	0.36414228	0.02114165	44	5	FALSE	BRF2	BRF2	69.20454545	0	44	0	0.70897012	FALSE	0	BRF2	57694	0.04119233
791260	taxon:9606	2.55096896	3.90E-05	169469	1902	WD repeat domain 18	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR18				WDR18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR18	0.39200791	0.1987315	44	4	FALSE	WDR18	WDR18	202.5681818	0	44	0	0.74150517	FALSE	0	WDR18	82810	0.07081306
791346	taxon:9606	2.55774382	7.90E-05	169071	1902	elaC ribonuclease Z 2	gene	biological_process-&-1&-GO:0042780-&&-tRNA 3'-end processing-%%-GO:0090646-&&-mitochondrial tRNA processing-%%-GO:0072684-&&-mitochondrial tRNA 3'-trailer cleavage, endonucleolytic|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004549-&&-tRNA-specific ribonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042781-&&-3'-tRNA processing endoribonuclease activity	G:9606:ELAC2			KEGG-&-1&-hsa03013-&&-RNA transport	ELAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELAC2	0.39096957	0.07610994	44	4	FALSE	ELAC2	ELAC2	140.8409091	0	44	0	0.74037603	FALSE	0	ELAC2	118674	0.04985026
791360	taxon:9606	2.44619505	1.10E-04	169002	1902	FK506 binding protein like	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:0009314-&&-response to radiation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FKBPL				FKBPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBPL	0.40879815	0.10676533	44	4	FALSE	FKBPL	FKBPL	156.3409091	0	44	0	0.75896749	FALSE	0	FKBPL	159166	0.0445859
791392	taxon:9606	2.56530644	7.45E-05	168826	1902	widely interspaced zinc finger motifs	gene	biological_process-&-1&-GO:0070208-&&-protein heterotrimerization-%%-GO:0050821-&&-protein stabilization-%%-GO:0010571-&&-positive regulation of nuclear cell cycle DNA replication|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030496-&&-midbody-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0070984-&&-SET domain binding-%%-GO:0005515-&&-protein binding	G:9606:WIZ				WIZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WIZ	0.38981698	0.09725159	44	4	FALSE	WIZ	WIZ	151.25	0	44	0	0.73911559	FALSE	0	WIZ	118998	0.0544668
791894	taxon:9606	2.53537104	8.85E-05	182918	1902	adenylosuccinate lyase	gene	biological_process-&-1&-GO:0001666-&&-response to hypoxia-%%-GO:0006189-&&-'de novo' IMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0044208-&&-'de novo' AMP biosynthetic process-%%-GO:0006164-&&-purine nucleotide biosynthetic process-%%-GO:0014850-&&-response to muscle activity-%%-GO:0042594-&&-response to starvation-%%-GO:0007584-&&-response to nutrient-%%-GO:0006167-&&-AMP biosynthetic process-%%-GO:0051262-&&-protein tetramerization-%%-GO:0009060-&&-aerobic respiration|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004018-&&-N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity-%%-GO:0070626-&&-(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	G:9606:ADSL			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	ADSL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADSL	0.39441959	0.102537	44	4	FALSE	ADSL	ADSL	136.4090909	0	44	0	0.74410483	FALSE	0	ADSL	127698	0.04612367
791994	taxon:9606	2.65747597	1.92E-04	182759	1902	apolipoprotein E	gene	biological_process-&-1&-GO:0097113-&&-AMPA glutamate receptor clustering-%%-GO:0017038-&&-protein import-%%-GO:0032489-&&-regulation of Cdc42 protein signal transduction-%%-GO:1900272-&&-negative regulation of long-term synaptic potentiation-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0010873-&&-positive regulation of cholesterol esterification-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0034380-&&-high-density lipoprotein particle assembly-%%-GO:1901630-&&-negative regulation of presynaptic membrane organization-%%-GO:0015909-&&-long-chain fatty acid transport-%%-GO:0046907-&&-intracellular transport-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:1905890-&&-regulation of cellular response to very-low-density lipoprotein particle stimulus-%%-GO:0034372-&&-very-low-density lipoprotein particle remodeling-%%-GO:0034447-&&-very-low-density lipoprotein particle clearance-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0031102-&&-neuron projection regeneration-%%-GO:0010877-&&-lipid transport involved in lipid storage-%%-GO:0090209-&&-negative regulation of triglyceride metabolic process-%%-GO:0034384-&&-high-density lipoprotein particle clearance-%%-GO:1905860-&&-positive regulation of heparan sulfate proteoglycan binding-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:1902430-&&-negative regulation of beta-amyloid formation-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0019068-&&-virion assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0097114-&&-NMDA glutamate receptor clustering-%%-GO:0034382-&&-chylomicron remnant clearance-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0019934-&&-cGMP-mediated signaling-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0034375-&&-high-density lipoprotein particle remodeling-%%-GO:0002021-&&-response to dietary excess-%%-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0048844-&&-artery morphogenesis-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:1902995-&&-positive regulation of phospholipid efflux-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0042311-&&-vasodilation-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:1903002-&&-positive regulation of lipid transport across blood brain barrier-%%-GO:1900221-&&-regulation of beta-amyloid clearance-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:1901628-&&-positive regulation of postsynaptic membrane organization-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0006707-&&-cholesterol catabolic process-%%-GO:0045541-&&-negative regulation of cholesterol biosynthetic process-%%-GO:0042159-&&-lipoprotein catabolic process-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0051651-&&-maintenance of location in cell-%%-GO:0033344-&&-cholesterol efflux-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0030516-&&-regulation of axon extension-%%-GO:1905855-&&-positive regulation of heparan sulfate binding-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0032805-&&-positive regulation of low-density lipoprotein particle receptor catabolic process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0033700-&&-phospholipid efflux-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:1902952-&&-positive regulation of dendritic spine maintenance-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0045807-&&-positive regulation of endocytosis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005769-&&-early endosome-%%-GO:0034362-&&-low-density lipoprotein particle-%%-GO:0034364-&&-high-density lipoprotein particle-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0042627-&&-chylomicron-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005615-&&-extracellular space-%%-GO:0034363-&&-intermediate-density lipoprotein particle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005319-&&-lipid transporter activity-%%-GO:0060228-&&-phosphatidylcholine-sterol O-acyltransferase activator activity-%%-GO:0008201-&&-heparin binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0070326-&&-very-low-density lipoprotein particle receptor binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0046911-&&-metal chelating activity-%%-GO:0015485-&&-cholesterol binding-%%-GO:0017127-&&-cholesterol transporter activity-%%-GO:0016209-&&-antioxidant activity-%%-GO:0008289-&&-lipid binding-%%-GO:0071813-&&-lipoprotein particle binding	G:9606:APOE	APOE	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa05010-&&-Alzheimer disease	APOE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOE	0.37629691	0.10569106	44	4	FALSE	APOE	APOE	80.04761905	0	43	0	0.723754	FALSE	1	APOE	161108	0.03649269
792163	taxon:9606	2.47171892	1.44E-04	182493	1902	adducin 1	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006884-&&-cell volume homeostasis-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0020027-&&-hemoglobin metabolic process-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0008290-&&-F-actin capping protein complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0003723-&&-RNA binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:ADD1				ADD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADD1	0.40457675	0.12473573	44	4	FALSE	ADD1	ADD1	181.3181818	0	44	0	0.75471351	FALSE	0	ADD1	193892	0.05404929
792550	taxon:9606	2.72081298	4.77E-05	181827	1902	caspase 10	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0031265-&&-CD95 death-inducing signaling complex-%%-GO:0005829-&&-cytosol-%%-GO:0097342-&&-ripoptosome|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0005515-&&-protein binding-%%-GO:0097199-&&-cysteine-type endopeptidase activity involved in apoptotic signaling pathway	G:9606:CASP10	CASP10	TRUE	KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05152-&&-Tuberculosis-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05161-&&-Hepatitis B	CASP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP10	0.36753721	0.21370499	44	4	FALSE	CASP10	CASP10	83	0	43	0	0.71319784	FALSE	1	CASP10	64282	0.045489
792647	taxon:9606	2.61241531	5.81E-05	181646	1902	CD40 molecule	gene	biological_process-&-1&-GO:0042832-&&-defense response to protozoan-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0006954-&&-inflammatory response-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0002768-&&-immune response-regulating cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030168-&&-platelet activation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0051607-&&-defense response to virus-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033590-&&-response to cobalamin-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0036018-&&-cellular response to erythropoietin-%%-GO:0090037-&&-positive regulation of protein kinase C signaling-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:1901652-&&-response to peptide|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0043196-&&-varicosity-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003823-&&-antigen binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0004872-&&-receptor activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:CD40			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria	CD40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD40	0.38278753	0.1300813	44	4	FALSE	CD40	CD40	125.3333333	0	43	0	0.73126411	FALSE	1	CD40	86426	0.05108702
792755	taxon:9606	2.46494407	1.23E-04	181429	1902	FES proto-oncogene, tyrosine kinase	gene	biological_process-&-1&-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0051297-&&-centrosome organization-%%-GO:0016477-&&-cell migration-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045639-&&-positive regulation of myeloid cell differentiation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0008283-&&-cell proliferation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0006935-&&-chemotaxis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005524-&&-ATP binding-%%-GO:0034987-&&-immunoglobulin receptor binding	G:9606:FES			KEGG-&-1&-hsa04360-&&-Axon guidance	FES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FES	0.40568872	0.13472706	44	4	FALSE	FES	FES	162.5	0	43	0	0.75584266	FALSE	1	FES	158112	0.04791421
793062	taxon:9606	2.66346305	4.52E-05	180813	1902	general transcription factor IIA subunit 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005672-&&-transcription factor TFIIA complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:GTF2A1			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis	GTF2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2A1	0.37545105	0.08130081	44	4	FALSE	GTF2A1	GTF2A1	98.38095238	0	43	0	0.72275616	FALSE	1	GTF2A1	64006	0.04519867
793181	taxon:9606	2.46163542	1.88E-04	164194	1902	copper metabolism domain containing 1	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:0015031-&&-protein transport-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0055070-&&-copper ion homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1902306-&&-negative regulation of sodium ion transmembrane transport-%%-GO:0048227-&&-plasma membrane to endosome transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0055037-&&-recycling endosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0070300-&&-phosphatidic acid binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:COMMD1				COMMD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD1	0.406234	0.18002323	44	4	FALSE	COMMD1	COMMD1	216	0	43	0	0.7563941	FALSE	1	COMMD1	235696	0.06341515
793201	taxon:9606	2.59335119	8.65E-05	180536	1902	protein arginine methyltransferase 2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0034969-&&-histone arginine methylation-%%-GO:0048588-&&-developmental cell growth-%%-GO:0016571-&&-histone methylation-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035189-&&-Rb-E2F complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0042054-&&-histone methyltransferase activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0033142-&&-progesterone receptor binding-%%-GO:0042974-&&-retinoic acid receptor binding	G:9606:PRMT2				PRMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT2	0.38560146	0.06968641	44	4	FALSE	PRMT2	PRMT2	122.0238095	0	43	0	0.73444147	FALSE	1	PRMT2	114542	0.04703116
793370	taxon:9606	2.50055144	3.37E-04	180225	1902	integrin subunit alpha V	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:2000425-&&-regulation of apoptotic cell clearance-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0001525-&&-angiogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016049-&&-cell growth-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0045715-&&-negative regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:2000536-&&-negative regulation of entry of bacterium into host cell-%%-GO:0016477-&&-cell migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0032369-&&-negative regulation of lipid transport-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0038027-&&-apolipoprotein A-I-mediated signaling pathway-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0007155-&&-cell adhesion-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0050748-&&-negative regulation of lipoprotein metabolic process-%%-GO:0052066-&&-entry of symbiont into host cell by promotion of host phagocytosis-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0001570-&&-vasculogenesis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050919-&&-negative chemotaxis|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0034683-&&-integrin alphav-beta3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0031528-&&-microvillus membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0034686-&&-integrin alphav-beta8 complex-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0035867-&&-alphav-beta3 integrin-IGF-1-IGF1R complex-%%-GO:0008305-&&-integrin complex-%%-GO:0034684-&&-integrin alphav-beta5 complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031527-&&-filopodium membrane|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001846-&&-opsonin binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0019960-&&-C-X3-C chemokine binding-%%-GO:0005102-&&-receptor binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0005245-&&-voltage-gated calcium channel activity-%%-GO:0038132-&&-neuregulin binding-%%-GO:1990430-&&-extracellular matrix protein binding-%%-GO:0042277-&&-peptide binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0002020-&&-protease binding	G:9606:ITGAV	ITGAV	TRUE	KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04145-&&-Phagosome-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGAV	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGAV	0.39991179	0.0961945	44	4	FALSE	ITGAV	ITGAV	143.7727273	0	44	0	0.74990809	FALSE	0	ITGAV	351342	0.04569317
787213	taxon:9606	2.50890184	3.07E-05	179852	1902	methyl-CpG binding domain protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030182-&&-neuron differentiation-%%-GO:0042220-&&-response to cocaine-%%-GO:0042493-&&-response to drug-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0044030-&&-regulation of DNA methylation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0010385-&&-double-stranded methylated DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:MBD1				MBD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBD1	0.39858076	0.27685493	43	4	FALSE	MBD1	MBD1	234.1162791	0	43	0	0.74851636	FALSE	0	MBD1	91452	0.07483792
787369	taxon:9606	2.61903261	5.75E-05	179549	1902	MYB proto-oncogene like 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0031523-&&-Myb complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:MYBL2			KEGG-&-1&-hsa04218-&&-Cellular senescence	MYBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYBL2	0.38182037	0.12317073	43	4	FALSE	MYBL2	MYBL2	130.4146342	0	42	0	0.73016123	FALSE	1	MYBL2	86390	0.05371888
787501	taxon:9606	2.80967386	7.06E-04	179335	1902	matrix metallopeptidase 2	gene	biological_process-&-1&-GO:0060346-&&-bone trabecula formation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0001957-&&-intramembranous ossification-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0006508-&&-proteolysis-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0060325-&&-face morphogenesis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007566-&&-embryo implantation-%%-GO:0001955-&&-blood vessel maturation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0030017-&&-sarcomere-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:MMP2	MMP2	TRUE	KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa01522-&&-Endocrine resistance-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	MMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP2	0.35591319	0.03658537	43	4	FALSE	MMP2	MMP2	41.02439024	0	42	0	0.69838769	FALSE	1	MMP2	673876	0.03116116
787609	taxon:9606	2.47045848	5.59E-05	179105	1902	nuclear transcription factor Y subunit alpha	gene	biological_process-&-1&-GO:0048511-&&-rhythmic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016602-&&-CCAAT-binding factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding	G:9606:NFYA			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05152-&&-Tuberculosis	NFYA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFYA	0.40478316	0.17195122	43	4	FALSE	NFYA	NFYA	183.3414634	0	42	0	0.75492359	FALSE	1	NFYA	109492	0.0544614
787644	taxon:9606	2.73877422	9.48E-05	179027	1902	neuroblastoma RAS viral oncogene homolog	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0072600-&&-establishment of protein localization to Golgi-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0005525-&&-GTP binding	G:9606:NRAS	NRAS	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05218-&&-Melanoma-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	NRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRAS	0.36512685	0.04208195	43	4	FALSE	NRAS	NRAS	68.65116279	0	43	0	0.7102043	FALSE	0	NRAS	100442	0.04043591
787690	taxon:9606	2.54104301	5.60E-05	178943	1902	plakophilin 2	gene	biological_process-&-1&-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0086019-&&-cell-cell signaling involved in cardiac conduction-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0034334-&&-adherens junction maintenance-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0016264-&&-gap junction assembly-%%-GO:0048496-&&-maintenance of animal organ identity-%%-GO:0002159-&&-desmosome assembly-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0070268-&&-cornification-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0045110-&&-intermediate filament bundle assembly-%%-GO:0007507-&&-heart development-%%-GO:0031424-&&-keratinization-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0086001-&&-cardiac muscle cell action potential|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005882-&&-intermediate filament-%%-GO:0005886-&&-plasma membrane-%%-GO:0030057-&&-desmosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0001533-&&-cornified envelope-%%-GO:0005912-&&-adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding-%%-GO:0003674-&&-molecular_function-%%-GO:0019215-&&-intermediate filament binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication-%%-GO:0044325-&&-ion channel binding-%%-GO:0045294-&&-alpha-catenin binding	G:9606:PKP2			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	PKP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKP2	0.39353919	0.13170732	43	4	FALSE	PKP2	PKP2	185.8292683	0	42	0	0.7431595	FALSE	1	PKP2	112656	0.06315257
787697	taxon:9606	2.4394202	2.06E-04	178924	1902	phospholipase D2	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0048870-&&-cell motility-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0048017-&&-inositol lipid-mediated signaling-%%-GO:0036465-&&-synaptic vesicle recycling-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006654-&&-phosphatidic acid biosynthetic process|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0098793-&&-presynapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0070290-&&-N-acylphosphatidylethanolamine-specific phospholipase D activity-%%-GO:0005515-&&-protein binding-%%-GO:0004630-&&-phospholipase D activity	G:9606:PLD2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04144-&&-Endocytosis-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	PLD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLD2	0.40993348	0.10299003	43	4	FALSE	PLD2	PLD2	182.8604651	0	43	0	0.76009663	FALSE	0	PLD2	269328	0.05171688
787769	taxon:9606	2.53773436	1.12E-04	178808	1902	protein phosphatase, Mg2+/Mn2+ dependent 1A	gene	biological_process-&-1&-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016311-&&-dephosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0010991-&&-negative regulation of SMAD protein complex assembly-%%-GO:0006499-&&-N-terminal protein myristoylation-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0033192-&&-calmodulin-dependent protein phosphatase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0030145-&&-manganese ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:PPM1A			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PPM1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1A	0.39405228	0.11849391	43	4	FALSE	PPM1A	PPM1A	144	0	43	0	0.74371094	FALSE	0	PPM1A	134870	0.04902427
787924	taxon:9606	2.44572239	7.07E-05	178594	1902	ornithine aminotransferase	gene	biological_process-&-1&-GO:0055129-&&-L-proline biosynthetic process-%%-GO:0007601-&&-visual perception-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0034214-&&-protein hexamerization|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004587-&&-ornithine-oxo-acid transaminase activity	G:9606:OAT			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	OAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OAT	0.40887715	0.11097561	43	4	FALSE	OAT	OAT	230.3902439	0	42	0	0.75904627	FALSE	1	OAT	154128	0.06559176
788030	taxon:9606	2.52497243	5.67E-05	178332	1902	Rho associated coiled-coil containing protein kinase 1	gene	biological_process-&-1&-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0032060-&&-bleb assembly-%%-GO:0050900-&&-leukocyte migration-%%-GO:0051451-&&-myoblast migration-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0045616-&&-regulation of keratinocyte differentiation-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:1903347-&&-negative regulation of bicellular tight junction assembly-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0003383-&&-apical constriction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0035509-&&-negative regulation of myosin-light-chain-phosphatase activity-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0022614-&&-membrane to membrane docking-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0030027-&&-lamellipodium-%%-GO:0032059-&&-bleb-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0017049-&&-GTP-Rho binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:ROCK1	ROCK1	TRUE	KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	ROCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROCK1	0.39604393	0.09268293	43	4	FALSE	ROCK1	ROCK1	144.2439024	0	42	0	0.74583793	FALSE	1	ROCK1	92254	0.04788885
788180	taxon:9606	2.50764141	8.47E-05	178117	1902	Rap1 GTPase-GDP dissociation stimulator 1	gene	biological_process-&-1&-GO:0014829-&&-vascular smooth muscle contraction-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:0031034-&&-myosin filament assembly-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RAP1GDS1				RAP1GDS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP1GDS1	0.3987811	0.11738649	43	4	FALSE	RAP1GDS1	RAP1GDS1	145.6046512	0	43	0	0.74872643	FALSE	0	RAP1GDS1	122004	0.04662343
788237	taxon:9606	2.69040492	1.68E-04	178029	1902	sex hormone binding globulin	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005496-&&-steroid binding-%%-GO:0005497-&&-androgen binding	G:9606:SHBG	SHBG	TRUE		SHBG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHBG	0.37169126	0.02682927	43	4	FALSE	SHBG	SHBG	80.85365854	0	42	0	0.71826585	FALSE	1	SHBG	175910	0.04089026
788560	taxon:9606	2.54104301	7.91E-05	177437	1902	synapsin I	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046928-&&-regulation of neurotransmitter secretion-%%-GO:0097091-&&-synaptic vesicle clustering-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis|cellular_component-&-1&-GO:0098993-&&-anchored component of synaptic vesicle membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043195-&&-terminal bouton-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0005829-&&-cytosol-%%-GO:0000795-&&-synaptonemal complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0003824-&&-catalytic activity	G:9606:SYN1				SYN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYN1	0.39353919	0.0902439	43	4	FALSE	SYN1	SYN1	146	0	42	0	0.7431595	FALSE	1	SYN1	125714	0.04994988
788574	taxon:9606	2.68347251	5.68E-05	177414	1902	TATA-box binding protein associated factor 7	gene	biological_process-&-1&-GO:0000296-&&-spermine transport-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0060260-&&-regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0071339-&&-MLL1 complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0061628-&&-H3K27me3 modified histone binding	G:9606:TAF7			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF7	0.37265148	0.16341463	43	5	FALSE	TAF7	TAF7	97.85365854	0	42	0	0.71942125	FALSE	1	TAF7	74884	0.04740772
788719	taxon:9606	2.36521191	1.34E-04	177127	1902	tumor protein, translationally-controlled 1	gene	biological_process-&-1&-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0030154-&&-cell differentiation-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0009615-&&-response to virus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006816-&&-calcium ion transport-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0045298-&&-tubulin complex-%%-GO:0005771-&&-multivesicular body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0003723-&&-RNA binding	G:9606:TPT1				TPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPT1	0.4227951	0.1304878	43	4	FALSE	TPT1	TPT1	226.8048781	0	42	0	0.77246468	FALSE	1	TPT1	214082	0.05647116
788722	taxon:9606	2.522294	8.09E-05	177123	1902	nuclear receptor subfamily 2 group C member 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0021549-&&-cerebellum development-%%-GO:0048520-&&-positive regulation of behavior-%%-GO:0040019-&&-positive regulation of embryonic development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045663-&&-positive regulation of myoblast differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004872-&&-receptor activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NR2C2				NR2C2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR2C2	0.39646449	0.17073171	43	4	FALSE	NR2C2	NR2C2	169.8048781	0	42	0	0.74628433	FALSE	1	NR2C2	117498	0.0557251
788763	taxon:9606	2.54277611	5.73E-05	176988	1902	tripartite motif containing 26	gene	biological_process-&-1&-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045087-&&-innate immune response-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:TRIM26				TRIM26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM26	0.39327096	0.08414634	43	4	FALSE	TRIM26	TRIM26	155.0731707	0	42	0	0.74287065	FALSE	1	TRIM26	109048	0.05321279
788783	taxon:9606	2.66346305	1.42E-04	176914	1902	C-X-C motif chemokine receptor 4	gene	biological_process-&-1&-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0050920-&&-regulation of chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0030260-&&-entry into host cell-%%-GO:0043217-&&-myelin maintenance-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0006954-&&-inflammatory response-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0009615-&&-response to virus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0005770-&&-late endosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005764-&&-lysosome-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0003779-&&-actin binding-%%-GO:0016494-&&-C-X-C chemokine receptor activity-%%-GO:0015026-&&-coreceptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0032027-&&-myosin light chain binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019955-&&-cytokine binding	G:9606:CXCR4	CXCR4	TRUE	KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04144-&&-Endocytosis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	CXCR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCR4	0.37545105	0.11341463	43	4	FALSE	CXCR4	CXCR4	98.17073171	0	42	0	0.72275616	FALSE	1	CXCR4	153126	0.04600185
788960	taxon:9606	2.51551914	6.65E-05	176530	1902	PTPRF interacting protein alpha 1	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0090005-&&-negative regulation of establishment of protein localization to plasma membrane|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0048786-&&-presynaptic active zone|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:PPFIA1				PPFIA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPFIA1	0.39753226	0.09878049	43	4	FALSE	PPFIA1	PPFIA1	158.6341463	0	42	0	0.74741348	FALSE	1	PPFIA1	100000	0.05146587
789100	taxon:9606	2.49377659	5.24E-05	176193	1902	eukaryotic translation initiation factor 2B subunit beta	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0051716-&&-cellular response to stimulus-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0009749-&&-response to glucose-%%-GO:0007417-&&-central nervous system development-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006413-&&-translational initiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005525-&&-GTP binding	G:9606:EIF2B2			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2B2	0.40099823	0.25581395	43	4	FALSE	EIF2B2	EIF2B2	160.9767442	0	43	0	0.75103724	FALSE	0	EIF2B2	99686	0.05003217
789107	taxon:9606	2.48936505	3.94E-05	176186	1902	pre-mRNA processing factor 4B	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:PRPF4B				PRPF4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPF4B	0.40170886	0.28239203	43	4	FALSE	PRPF4B	PRPF4B	212.3255814	0	43	0	0.75177249	FALSE	0	PRPF4B	80630	0.0651834
789108	taxon:9606	2.47691823	1.33E-04	176181	1902	adaptor related protein complex 1 mu 1 subunit	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0032438-&&-melanosome organization-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0035646-&&-endosome to melanosome transport-%%-GO:0016032-&&-viral process-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AP1M1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1M1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1M1	0.4037275	0.09413068	43	4	FALSE	AP1M1	AP1M1	144.8604651	0	43	0	0.75384696	FALSE	0	AP1M1	185942	0.04355218
789130	taxon:9606	2.47487002	4.97E-05	176146	1902	H1 histone family member X	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000786-&&-nucleosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:H1FX				H1FX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H1FX	0.40406162	0.213732	43	4	FALSE	H1FX	H1FX	273.0465116	0	43	0	0.75418833	FALSE	0	H1FX	121664	0.08179247
789165	taxon:9606	2.43091224	5.97E-05	176061	1902	ubiquitin specific peptidase 10	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006914-&&-autophagy-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP10				USP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP10	0.4113682	0.15	43	4	FALSE	USP10	USP10	226.6097561	0	42	0	0.76151463	FALSE	1	USP10	111082	0.06277666
789232	taxon:9606	2.57050575	1.09E-04	175958	1902	protein activator of interferon induced protein kinase EIF2AK2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030422-&&-production of siRNA involved in RNA interference-%%-GO:0009615-&&-response to virus-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006955-&&-immune response-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:PRKRA				PRKRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKRA	0.3890285	0.13780488	43	4	FALSE	PRKRA	PRKRA	156.0243902	0	42	0	0.73824904	FALSE	1	PRKRA	134988	0.0566123
789247	taxon:9606	2.39751063	8.94E-05	175899	1902	NUMB, endocytic adaptor protein	gene	biological_process-&-1&-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0034332-&&-adherens junction organization-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0007409-&&-axonogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030862-&&-positive regulation of polarized epithelial cell differentiation-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0021849-&&-neuroblast division in subventricular zone|cellular_component-&-1&-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0045177-&&-apical part of cell-%%-GO:0005769-&&-early endosome-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0045294-&&-alpha-catenin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:NUMB			KEGG-&-1&-hsa04330-&&-Notch signaling pathway	NUMB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUMB	0.4170993	0.13289037	43	4	FALSE	NUMB	NUMB	188.9767442	0	43	0	0.76708156	FALSE	0	NUMB	159508	0.04964704
789307	taxon:9606	2.7130928	1.43E-04	175777	1902	protein interacting with PRKCA 1	gene	biological_process-&-1&-GO:0043113-&&-receptor clustering-%%-GO:0015844-&&-monoamine transport-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0036294-&&-cellular response to decreased oxygen levels-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0034316-&&-negative regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0097061-&&-dendritic spine organization-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0021782-&&-glial cell development-%%-GO:0043045-&&-DNA methylation involved in embryo development-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0097062-&&-dendritic spine maintenance-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0045161-&&-neuronal ion channel clustering|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016235-&&-aggresome-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045202-&&-synapse-%%-GO:0014069-&&-postsynaptic density-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0071933-&&-Arp2/3 complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0019899-&&-enzyme binding	G:9606:PICK1				PICK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PICK1	0.36858304	0.05243902	43	4	FALSE	PICK1	PICK1	68.04878049	0	42	0	0.71448453	FALSE	1	PICK1	119994	0.03689091
789398	taxon:9606	2.70852371	4.29E-05	175568	1902	ATPase H+ transporting V1 subunit F	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0015992-&&-proton transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification|cellular_component-&-1&-GO:0016469-&&-proton-transporting two-sector ATPase complex-%%-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0016471-&&-vacuolar proton-transporting V-type ATPase complex|molecular_function-&-1&-GO:0015078-&&-hydrogen ion transmembrane transporter activity-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism-%%-GO:0042624-&&-ATPase activity, uncoupled-%%-GO:0005515-&&-protein binding-%%-GO:0042625-&&-ATPase coupled ion transmembrane transporter activity	G:9606:ATP6V1F			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V1F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1F	0.36920482	0.13732004	43	4	FALSE	ATP6V1F	ATP6V1F	90.1627907	0	43	0	0.71524605	FALSE	0	ATP6V1F	66458	0.04699688
789436	taxon:9606	2.43784465	7.14E-05	175482	1902	lon peptidase 1, mitochondrial	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0001666-&&-response to hypoxia-%%-GO:0010044-&&-response to aluminum ion-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0007568-&&-aging-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032042-&&-mitochondrial DNA metabolic process-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0000002-&&-mitochondrial genome maintenance-%%-GO:0070407-&&-oxidation-dependent protein catabolic process-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004176-&&-ATP-dependent peptidase activity-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0070362-&&-mitochondrial heavy strand promoter anti-sense binding-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0043531-&&-ADP binding-%%-GO:0070364-&&-mitochondrial heavy strand promoter sense binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0070363-&&-mitochondrial light strand promoter sense binding-%%-GO:0070361-&&-mitochondrial light strand promoter anti-sense binding	G:9606:LONP1				LONP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LONP1	0.41019841	0.13170732	43	4	FALSE	LONP1	LONP1	223.4634146	0	42	0	0.76035922	FALSE	1	LONP1	156806	0.06270408
789503	taxon:9606	2.4362691	1.12E-04	175326	1902	eukaryotic translation initiation factor 5B	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:EIF5B			KEGG-&-1&-hsa03013-&&-RNA transport	EIF5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF5B	0.41046369	0.12624585	43	4	FALSE	EIF5B	EIF5B	223.3255814	0	43	0	0.76062182	FALSE	0	EIF5B	167016	0.06246665
789772	taxon:9606	2.40050418	8.36E-05	174722	1902	CCAAT/enhancer binding protein zeta	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:CEBPZ				CEBPZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPZ	0.41657915	0.19047619	43	4	FALSE	CEBPZ	CEBPZ	245.4186047	0	43	0	0.76658264	FALSE	0	CEBPZ	173524	0.0647297
789777	taxon:9606	2.65259178	7.89E-05	174702	1902	sorbin and SH3 domain containing 3	gene	biological_process-&-1&-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0006936-&&-muscle contraction-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0007155-&&-cell adhesion-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051495-&&-positive regulation of cytoskeleton organization-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0017166-&&-vinculin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:SORBS3				SORBS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORBS3	0.37698978	0.05609756	43	4	FALSE	SORBS3	SORBS3	104.4634146	0	42	0	0.72456804	FALSE	1	SORBS3	98120	0.04692542
789818	taxon:9606	2.67118324	8.15E-05	174590	1902	ubiquitin specific peptidase 20	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006897-&&-endocytosis-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP20				USP20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP20	0.37436593	0.05609756	43	4	FALSE	USP20	USP20	89.68292683	0	42	0	0.72146946	FALSE	1	USP20	83726	0.04222496
789901	taxon:9606	2.62801323	1.05E-04	174403	1902	STAM binding protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0032154-&&-cleavage furrow-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:STAMBP	STAMBP	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis	STAMBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAMBP	0.38051559	0.08637874	43	4	FALSE	STAMBP	STAMBP	105.4883721	0	43	0	0.72866446	FALSE	0	STAMBP	122114	0.04465669
789999	taxon:9606	2.45454545	7.59E-05	174145	1902	protein phosphatase 6 regulatory subunit 1	gene	biological_process-&-1&-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:PPP6R1				PPP6R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP6R1	0.40740741	0.09745293	43	4	FALSE	PPP6R1	PPP6R1	169.1395349	0	43	0	0.75757576	FALSE	0	PPP6R1	132406	0.04889908
790247	taxon:9606	2.69245313	9.52E-05	173529	1902	ubiquitin specific peptidase 22	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0009790-&&-embryo development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016574-&&-histone ubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0070461-&&-SAGA-type complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0010485-&&-H4 histone acetyltransferase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:USP22				USP22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP22	0.37140851	0.11219512	43	4	FALSE	USP22	USP22	86.56097561	0	42	0	0.71792448	FALSE	1	USP22	96970	0.04300513
790303	taxon:9606	2.49944856	1.08E-04	173377	1902	HECT domain E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HECTD1				HECTD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HECTD1	0.40008825	0.07804878	43	4	FALSE	HECTD1	HECTD1	161.3170732	0	42	0	0.75009191	FALSE	1	HECTD1	148938	0.05058065
790531	taxon:9606	2.47660312	6.07E-05	172576	1902	DIM1 dimethyladenosine transferase 1 homolog	gene	biological_process-&-1&-GO:0031167-&&-rRNA methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0000179-&&-rRNA (adenine-N6,N6-)-dimethyltransferase activity-%%-GO:0052909-&&-18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	G:9606:DIMT1				DIMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIMT1	0.40377887	0.2469546	43	4	FALSE	DIMT1	DIMT1	208.7674419	0	43	0	0.75389948	FALSE	0	DIMT1	108524	0.06313197
790736	taxon:9606	2.65621553	6.12E-05	171355	1902	SBDS ribosome assembly guanine nucleotide exchange factor	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0030282-&&-bone mineralization-%%-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0008283-&&-cell proliferation-%%-GO:0048539-&&-bone marrow development-%%-GO:0042256-&&-mature ribosome assembly-%%-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0003723-&&-RNA binding	G:9606:SBDS			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	SBDS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SBDS	0.37647547	0.08748616	43	4	FALSE	SBDS	SBDS	100.5348837	0	43	0	0.72396408	FALSE	0	SBDS	88154	0.04502034
790871	taxon:9606	2.58689144	8.07E-05	170817	1902	carboxypeptidase, vitellogenic like	gene	biological_process-&-1&-GO:0051603-&&-proteolysis involved in cellular protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004185-&&-serine-type carboxypeptidase activity	G:9606:CPVL				CPVL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPVL	0.38656435	0.12181617	43	4	FALSE	CPVL	CPVL	201.3488372	0	43	0	0.73551809	FALSE	0	CPVL	151452	0.07629987
790891	taxon:9606	2.48479597	9.58E-05	170756	1902	3-hydroxyacyl-CoA dehydratase 3	gene	biological_process-&-1&-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0046726-&&-positive regulation by virus of viral protein levels in host cell-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0030497-&&-fatty acid elongation-%%-GO:0042761-&&-very long-chain fatty acid biosynthetic process-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045070-&&-positive regulation of viral genome replication|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0102344-&&-3-hydroxy-behenoyl-CoA dehydratase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0018812-&&-3-hydroxyacyl-CoA dehydratase activity-%%-GO:0102345-&&-3-hydroxy-lignoceroyl-CoA dehydratase activity	G:9606:HACD3			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids	HACD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HACD3	0.40244753	0.08748616	43	4	FALSE	HACD3	HACD3	211.4186047	0	43	0	0.75253401	FALSE	0	HACD3	187218	0.06464533
790963	taxon:9606	2.67464944	4.87E-05	170583	1902	PIH1 domain containing 1	gene	biological_process-&-1&-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0051569-&&-regulation of histone H3-K4 methylation-%%-GO:0006364-&&-rRNA processing-%%-GO:1903939-&&-regulation of TORC2 signaling-%%-GO:2000619-&&-negative regulation of histone H4-K16 acetylation-%%-GO:0048254-&&-snoRNA localization-%%-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:1904263-&&-positive regulation of TORC1 signaling-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:2001268-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:1902661-&&-positive regulation of glucose mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071169-&&-establishment of protein localization to chromatin-%%-GO:1900110-&&-negative regulation of histone H3-K9 dimethylation|cellular_component-&-1&-GO:0097255-&&-R2TP complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070761-&&-pre-snoRNP complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0001165-&&-RNA polymerase I upstream control element sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042393-&&-histone binding	G:9606:PIH1D1				PIH1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIH1D1	0.37388077	0.15946844	43	4	FALSE	PIH1D1	PIH1D1	98.27906977	0	43	0	0.72089176	FALSE	0	PIH1D1	70976	0.04627052
791044	taxon:9606	2.66803214	7.84E-05	170261	1902	OCIA domain containing 1	gene	cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:OCIAD1				OCIAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OCIAD1	0.37480808	0.09146341	43	4	FALSE	OCIAD1	OCIAD1	91.80487805	0	42	0	0.72199464	FALSE	1	OCIAD1	94178	0.04259784
791108	taxon:9606	2.57743816	4.17E-05	170017	1902	WD repeat domain 33	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0006301-&&-postreplication repair-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005581-&&-collagen trimer-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:WDR33			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	WDR33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR33	0.38798215	0.14174972	43	4	FALSE	WDR33	WDR33	163.4418605	0	43	0	0.73709364	FALSE	0	WDR33	81818	0.06009391
791312	taxon:9606	2.59083031	3.87E-05	169220	1902	translocase of outer mitochondrial membrane 22	gene	biological_process-&-1&-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0016236-&&-macroautophagy-%%-GO:0045040-&&-protein import into mitochondrial outer membrane-%%-GO:0030150-&&-protein import into mitochondrial matrix|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0016020-&&-membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0015266-&&-protein channel activity	G:9606:TOMM22				TOMM22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM22	0.38597665	0.15060908	43	4	FALSE	TOMM22	TOMM22	132.4651163	0	43	0	0.73486161	FALSE	0	TOMM22	75018	0.05032869
791376	taxon:9606	2.60091382	4.01E-05	168908	1902	microtubule affinity regulating kinase 4	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0007399-&&-nervous system development-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001578-&&-microtubule bundle formation|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0036064-&&-ciliary basal body-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0050321-&&-tau-protein kinase activity-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MARK4				MARK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARK4	0.38448025	0.11219512	43	4	FALSE	MARK4	MARK4	137.9268293	0	42	0	0.73318103	FALSE	1	MARK4	82884	0.05417817
791540	taxon:9606	2.45864188	4.51E-05	168182	1902	BRCA1/BRCA2-containing complex subunit 3	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0070537-&&-histone H2A K63-linked deubiquitination-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0051301-&&-cell division-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0010165-&&-response to X-ray-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0000152-&&-nuclear ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0070552-&&-BRISC complex-%%-GO:0005634-&&-nucleus-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:BRCC3			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa03440-&&-Homologous recombination	BRCC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRCC3	0.40672861	0.21219512	43	4	FALSE	BRCC3	BRCC3	208.7073171	0	42	0	0.75689302	FALSE	1	BRCC3	89462	0.06076253
791588	taxon:9606	2.47707578	9.42E-05	167913	1902	WD repeat domain 26	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR26	WDR26	TRUE		WDR26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR26	0.40370182	0.12846069	43	4	FALSE	WDR26	WDR26	187.7674419	0	43	0	0.7538207	FALSE	0	WDR26	139146	0.05662773
791682	taxon:9606	2.51646447	8.86E-05	167453	1902	UBX domain protein 6	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:UBXN6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	UBXN6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN6	0.39738292	0.10963455	43	4	FALSE	UBXN6	UBXN6	153.5348837	0	43	0	0.74725592	FALSE	0	UBXN6	121046	0.05022525
791862	taxon:9606	2.54246101	9.39E-05	182961	1902	acetyl-CoA acetyltransferase 2	gene	biological_process-&-1&-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003985-&&-acetyl-CoA C-acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:ACAT2			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis-%%-hsa04975-&&-Fat digestion and absorption-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00071-&&-Fatty acid degradation-%%-hsa00072-&&-Synthesis and degradation of ketone bodies-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	ACAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAT2	0.3933197	0.08658537	43	4	FALSE	ACAT2	ACAT2	146.902439	0	42	0	0.74292317	FALSE	1	ACAT2	129740	0.05030227
792465	taxon:9606	2.60737356	1.13E-04	165589	1902	TIR domain containing adaptor protein	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0032648-&&-regulation of interferon-beta production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0034137-&&-positive regulation of toll-like receptor 2 signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process-%%-GO:2000340-&&-positive regulation of chemokine (C-X-C motif) ligand 1 production-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:2000343-&&-positive regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0071221-&&-cellular response to bacterial lipopeptide-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0032738-&&-positive regulation of interleukin-15 production-%%-GO:0035665-&&-TIRAP-dependent toll-like receptor 4 signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0035663-&&-Toll-like receptor 2 binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0035662-&&-Toll-like receptor 4 binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:TIRAP			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05133-&&-Pertussis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05161-&&-Hepatitis B	TIRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIRAP	0.38352771	0.07560976	43	5	FALSE	TIRAP	TIRAP	101.2195122	0	42	0	0.73210441	FALSE	1	TIRAP	120688	0.04052322
792712	taxon:9606	2.69970065	1.07E-04	181512	1902	deoxyguanosine kinase	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0046070-&&-dGTP metabolic process-%%-GO:0009157-&&-deoxyribonucleoside monophosphate biosynthetic process-%%-GO:0008617-&&-guanosine metabolic process-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0043101-&&-purine-containing compound salvage-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046122-&&-purine deoxyribonucleoside metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0019206-&&-nucleoside kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004138-&&-deoxyguanosine kinase activity	G:9606:DGUOK	DGUOK	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	DGUOK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DGUOK	0.37041144	0.03902439	43	4	FALSE	DGUOK	DGUOK	67.65853659	0	42	0	0.71671656	FALSE	1	DGUOK	114532	0.03479994
792854	taxon:9606	2.53962502	8.56E-05	181266	1902	ERCC excision repair 3, TFIIH core complex helicase subunit	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006265-&&-DNA topological change-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006281-&&-DNA repair-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048568-&&-embryonic organ development-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0001666-&&-response to hypoxia-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0008104-&&-protein localization-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0009650-&&-UV protection-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035315-&&-hair cell differentiation-%%-GO:0009411-&&-response to UV-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0000439-&&-core TFIIH complex-%%-GO:0005675-&&-holo TFIIH complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0043138-&&-3'-5' DNA helicase activity-%%-GO:0016887-&&-ATPase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0032564-&&-dATP binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004386-&&-helicase activity-%%-GO:0003684-&&-damaged DNA binding	G:9606:ERCC3			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	ERCC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC3	0.39375892	0.15282392	43	4	FALSE	ERCC3	ERCC3	132.0465116	0	43	0	0.74339583	FALSE	0	ERCC3	118678	0.04469305
792996	taxon:9606	2.44320151	7.22E-05	164640	1902	eukaryotic translation initiation factor 5A-like 1	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0007568-&&-aging-%%-GO:0051028-&&-mRNA transport-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0045905-&&-positive regulation of translational termination-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0015031-&&-protein transport-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0006452-&&-translational frameshifting-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0045901-&&-positive regulation of translational elongation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0030425-&&-dendrite-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0003746-&&-translation elongation factor activity	G:9606:EIF5AL1				EIF5AL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF5AL1	0.40929903	0.15836102	43	4	FALSE	EIF5AL1	EIF5AL1	220.6046512	0	43	0	0.75946641	FALSE	0	EIF5AL1	140312	0.06271201
793016	taxon:9606	2.46888294	4.24E-05	180888	1902	G protein pathway suppressor 1	gene	biological_process-&-1&-GO:0000338-&&-protein deneddylation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0007049-&&-cell cycle-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:GPS1				GPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPS1	0.40504148	0.3200443	43	4	FALSE	GPS1	GPS1	219.627907	0	43	0	0.75518618	FALSE	0	GPS1	91994	0.06545593
793095	taxon:9606	2.54781787	1.10E-04	180740	1902	GATA binding protein 2	gene	biological_process-&-1&-GO:0033993-&&-response to lipid-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0001764-&&-neuron migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021902-&&-commitment of neuronal cell to specific neuron type in forebrain-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0070345-&&-negative regulation of fat cell proliferation-%%-GO:0001709-&&-cell fate determination-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0006909-&&-phagocytosis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010725-&&-regulation of primitive erythrocyte differentiation-%%-GO:0090102-&&-cochlea development-%%-GO:0048469-&&-cell maturation-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0097154-&&-GABAergic neuron differentiation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007596-&&-blood coagulation-%%-GO:0001655-&&-urogenital system development-%%-GO:0021983-&&-pituitary gland development-%%-GO:0035854-&&-eosinophil fate commitment-%%-GO:0035065-&&-regulation of histone acetylation-%%-GO:0045654-&&-positive regulation of megakaryocyte differentiation-%%-GO:2000977-&&-regulation of forebrain neuron differentiation-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0045650-&&-negative regulation of macrophage differentiation-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0021514-&&-ventral spinal cord interneuron differentiation-%%-GO:0021533-&&-cell differentiation in hindbrain-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0060872-&&-semicircular canal development-%%-GO:0045746-&&-negative regulation of Notch signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:GATA2				GATA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATA2	0.39249273	0.15946844	43	5	FALSE	GATA2	GATA2	170.2790698	0	43	0	0.74203036	FALSE	0	GATA2	194798	0.05919882
793342	taxon:9606	2.38411848	4.47E-05	180268	1902	high mobility group box 2	gene	biological_process-&-1&-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032392-&&-DNA geometric change-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0006325-&&-chromatin organization-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033151-&&-V(D)J recombination-%%-GO:0045654-&&-positive regulation of megakaryocyte differentiation-%%-GO:0032075-&&-positive regulation of nuclease activity-%%-GO:0006265-&&-DNA topological change-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007289-&&-spermatid nucleus differentiation-%%-GO:0008584-&&-male gonad development-%%-GO:0042493-&&-response to drug-%%-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000793-&&-condensed chromosome-%%-GO:0005623-&&-cell-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0097100-&&-supercoiled DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0044378-&&-non-sequence-specific DNA binding, bending-%%-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:HMGB2				HMGB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGB2	0.41944224	0.15282392	43	4	FALSE	HMGB2	HMGB2	253.372093	0	43	0	0.76931359	FALSE	0	HMGB2	126572	0.0652157
787017	taxon:9606	2.46132031	1.67E-04	180220	1902	integrin subunit beta 4	gene	biological_process-&-1&-GO:0009611-&&-response to wounding-%%-GO:0007155-&&-cell adhesion-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048565-&&-digestive tract development-%%-GO:0048870-&&-cell motility-%%-GO:0043588-&&-skin development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0097186-&&-amelogenesis-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0035878-&&-nail development-%%-GO:0006914-&&-autophagy-%%-GO:0072001-&&-renal system development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008305-&&-integrin complex-%%-GO:0030056-&&-hemidesmosome-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0043235-&&-receptor complex-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0038132-&&-neuregulin binding-%%-GO:0031994-&&-insulin-like growth factor I binding	G:9606:ITGB4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB4	0.40628601	0.10801394	42	4	FALSE	ITGB4	ITGB4	181.4761905	0	42	0	0.75644662	FALSE	0	ITGB4	188284	0.05328465
787149	taxon:9606	2.70978415	4.72E-05	179982	1902	LLGL2, scribble cell polarity complex component	gene	biological_process-&-1&-GO:0006887-&&-exocytosis-%%-GO:0032878-&&-regulation of establishment or maintenance of cell polarity-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0050708-&&-regulation of protein secretion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:LLGL2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	LLGL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LLGL2	0.36903308	0.02948718	42	4	FALSE	LLGL2	LLGL2	79.225	0	41	0	0.71503598	FALSE	1	LLGL2	59320	0.0422252
787209	taxon:9606	2.45013392	2.72E-05	179860	1902	methionine adenosyltransferase 2A	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0034214-&&-protein hexamerization-%%-GO:0006556-&&-S-adenosylmethionine biosynthetic process-%%-GO:0032259-&&-methylation|cellular_component-&-1&-GO:0048269-&&-methionine adenosyltransferase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004478-&&-methionine adenosyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MAT2A			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	MAT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAT2A	0.40814096	0.20641026	42	4	FALSE	MAT2A	MAT2A	316.025	0	41	0	0.75831101	FALSE	1	MAT2A	95738	0.09059633
787323	taxon:9606	2.48526863	2.71E-05	179664	1902	keratin 9	gene	biological_process-&-1&-GO:0043588-&&-skin development-%%-GO:0008544-&&-epidermis development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0045109-&&-intermediate filament organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:KRT9			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT9	0.40237099	0.21370499	42	4	FALSE	KRT9	KRT9	264.6428571	0	42	0	0.75245523	FALSE	0	KRT9	102688	0.08144631
787342	taxon:9606	2.55837403	5.36E-05	179620	1902	lysosomal associated membrane protein 2	gene	biological_process-&-1&-GO:0017038-&&-protein import-%%-GO:0050821-&&-protein stabilization-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0061740-&&-protein targeting to lysosome involved in chaperone-mediated autophagy-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006605-&&-protein targeting-%%-GO:1905146-&&-lysosomal protein catabolic process-%%-GO:0061684-&&-chaperone-mediated autophagy|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0098857-&&-membrane microdomain-%%-GO:0031902-&&-late endosome membrane-%%-GO:0044754-&&-autolysosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0097637-&&-integral component of autophagosome membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005764-&&-lysosome-%%-GO:0031088-&&-platelet dense granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:LAMP2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome	LAMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMP2	0.39087326	0.10384615	42	4	FALSE	LAMP2	LAMP2	155.825	0	41	0	0.74027099	FALSE	1	LAMP2	96836	0.05547543
787380	taxon:9606	2.47644556	1.66E-04	163140	1902	ubiquitin protein ligase E3 component n-recognin 1	gene	biological_process-&-1&-GO:0071233-&&-cellular response to leucine-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0071596-&&-ubiquitin-dependent protein catabolic process via the N-end rule pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0000502-&&-proteasome complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0070728-&&-leucine binding	G:9606:UBR1				UBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR1	0.40380456	0.08362369	42	4	FALSE	UBR1	UBR1	156.6190476	0	42	0	0.75392574	FALSE	0	UBR1	205354	0.04737366
787711	taxon:9606	2.43059713	6.61E-05	178906	1902	plastin 3	gene	biological_process-&-1&-GO:0060348-&&-bone development-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0051639-&&-actin filament network formation-%%-GO:0051017-&&-actin filament bundle assembly|cellular_component-&-1&-GO:0032432-&&-actin filament bundle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0051015-&&-actin filament binding	G:9606:PLS3				PLS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLS3	0.41142153	0.16724739	42	4	FALSE	PLS3	PLS3	198.9285714	0	42	0	0.76156714	FALSE	0	PLS3	134448	0.0552381
787957	taxon:9606	2.64109028	7.78E-05	178509	1902	pro-apoptotic WT1 regulator	gene	biological_process-&-1&-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042094-&&-interleukin-2 biosynthetic process-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:1901300-&&-positive regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0042986-&&-positive regulation of amyloid precursor protein biosynthetic process-%%-GO:2000774-&&-positive regulation of cellular senescence|cellular_component-&-1&-GO:0005884-&&-actin filament-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043522-&&-leucine zipper domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003779-&&-actin binding-%%-GO:0019899-&&-enzyme binding	G:9606:PAWR				PAWR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAWR	0.37863151	0.09230769	42	4	FALSE	PAWR	PAWR	116.225	0	41	0	0.72648495	FALSE	1	PAWR	102776	0.05063291
787979	taxon:9606	2.51047739	9.66E-05	178467	1902	cyclin dependent kinase 18	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK18				CDK18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK18	0.39833061	0.06852497	42	4	FALSE	CDK18	CDK18	153.452381	0	42	0	0.74825377	FALSE	0	CDK18	143574	0.04948903
788126	taxon:9606	2.50575075	9.51E-05	178203	1902	protein tyrosine phosphatase, receptor type F	gene	biological_process-&-1&-GO:0031102-&&-neuron projection regeneration-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0048679-&&-regulation of axon regeneration-%%-GO:1900121-&&-negative regulation of receptor binding-%%-GO:0007155-&&-cell adhesion-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0035373-&&-chondroitin sulfate proteoglycan binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRF			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04931-&&-Insulin resistance-%%-hsa04520-&&-Adherens junction	PTPRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRF	0.39908199	0.11025641	42	4	FALSE	PTPRF	PTPRF	154.2	0	41	0	0.74904154	FALSE	1	PTPRF	123212	0.04931978
788137	taxon:9606	2.61068221	1.25E-04	178173	1902	peroxisomal biogenesis factor 5	gene	biological_process-&-1&-GO:0016558-&&-protein import into peroxisome matrix-%%-GO:0016560-&&-protein import into peroxisome matrix, docking-%%-GO:1901094-&&-negative regulation of protein homotetramerization-%%-GO:0045046-&&-protein import into peroxisome membrane|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005777-&&-peroxisome-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0005052-&&-peroxisome matrix targeting signal-1 binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0000268-&&-peroxisome targeting sequence binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:PEX5			KEGG-&-1&-hsa04146-&&-Peroxisome	PEX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEX5	0.38304164	0.05	42	4	FALSE	PEX5	PEX5	107.025	0	41	0	0.73155296	FALSE	1	PEX5	131304	0.04283708
788154	taxon:9606	2.6368363	5.13E-05	178155	1902	RAB5B, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0015031-&&-protein transport-%%-GO:0007032-&&-endosome organization-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042470-&&-melanosome-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding-%%-GO:0005525-&&-GTP binding	G:9606:RAB5B	RAB5B	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05146-&&-Amoebiasis-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis	RAB5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB5B	0.37924235	0.1068525	42	4	FALSE	RAB5B	RAB5B	111.9761905	0	42	0	0.72719395	FALSE	0	RAB5B	79478	0.04802832
788463	taxon:9606	2.51189538	6.87E-05	177598	1902	solute carrier family 25 member 1	gene	biological_process-&-1&-GO:0006843-&&-mitochondrial citrate transport-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0035674-&&-tricarboxylic acid transmembrane transport-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0015142-&&-tricarboxylic acid transmembrane transporter activity-%%-GO:0015137-&&-citrate transmembrane transporter activity	G:9606:SLC25A1				SLC25A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A1	0.39810575	0.08826945	42	4	FALSE	SLC25A1	SLC25A1	191.7619048	0	42	0	0.74801744	FALSE	0	SLC25A1	159034	0.06196482
788472	taxon:9606	2.67071057	6.13E-05	177576	1902	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0003407-&&-neural retina development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0003219-&&-cardiac right ventricle formation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043393-&&-regulation of protein binding|cellular_component-&-1&-GO:0071564-&&-npBAF complex-%%-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:SMARCD3			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	SMARCD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMARCD3	0.37443219	0.18234611	42	4	FALSE	SMARCD3	SMARCD3	103.4761905	0	42	0	0.72154824	FALSE	0	SMARCD3	80594	0.04838782
788553	taxon:9606	2.65463999	6.24E-05	177449	1902	surfeit 4	gene	biological_process-&-1&-GO:0010638-&&-positive regulation of organelle organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032527-&&-protein exit from endoplasmic reticulum-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007030-&&-Golgi organization-%%-GO:0034498-&&-early endosome to Golgi transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SURF4				SURF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SURF4	0.37669891	0.0952381	42	4	FALSE	SURF4	SURF4	113.2142857	0	42	0	0.72422667	FALSE	0	SURF4	93910	0.05089942
788770	taxon:9606	2.60674334	4.05E-05	176941	1902	leucine zipper protein 1	gene	biological_process-&-1&-GO:0021503-&&-neural fold bending-%%-GO:0003281-&&-ventricular septum development-%%-GO:0060840-&&-artery development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane	G:9606:LUZP1				LUZP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUZP1	0.38362043	0.24041812	42	4	FALSE	LUZP1	LUZP1	146.6190476	0	42	0	0.73220944	FALSE	0	LUZP1	81728	0.05820946
788825	taxon:9606	2.53631637	5.53E-05	176804	1902	ubiquitin conjugating enzyme E2 V2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0006301-&&-postreplication repair-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0042275-&&-error-free postreplication DNA repair-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031372-&&-UBC13-MMS2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2V2				UBE2V2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2V2	0.39427258	0.17770035	42	4	FALSE	UBE2V2	UBE2V2	145.452381	0	42	0	0.74394727	FALSE	0	UBE2V2	97376	0.04932319
788872	taxon:9606	2.55790137	3.59E-05	176719	1902	vaccinia related kinase 1	gene	biological_process-&-1&-GO:0007084-&&-mitotic nuclear envelope reassembly-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0043987-&&-histone H3-S10 phosphorylation-%%-GO:0051301-&&-cell division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0072355-&&-histone H3-T3 phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005795-&&-Golgi stack-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0035175-&&-histone kinase activity (H3-S10 specific)-%%-GO:0005524-&&-ATP binding-%%-GO:0031493-&&-nucleosomal histone binding-%%-GO:0072354-&&-histone kinase activity (H3-T3 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:VRK1				VRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VRK1	0.39094549	0.18974359	42	4	FALSE	VRK1	VRK1	233.5	0	41	0	0.74034977	FALSE	1	VRK1	89318	0.0821831
788884	taxon:9606	2.45060659	3.14E-05	176682	1902	Werner syndrome RecQ like helicase	gene	biological_process-&-1&-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006284-&&-base-excision repair-%%-GO:0031297-&&-replication fork processing-%%-GO:0007568-&&-aging-%%-GO:0051345-&&-positive regulation of hydrolase activity-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0044806-&&-G-quadruplex DNA unwinding-%%-GO:0000732-&&-strand displacement-%%-GO:0032066-&&-nucleolus to nucleoplasm transport-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0010225-&&-response to UV-C-%%-GO:0000723-&&-telomere maintenance-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006260-&&-DNA replication-%%-GO:0007420-&&-brain development-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0006302-&&-double-strand break repair-%%-GO:0040009-&&-regulation of growth rate-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0090656-&&-t-circle formation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0001302-&&-replicative cell aging-%%-GO:0007569-&&-cell aging-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0098530-&&-positive regulation of strand invasion|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005694-&&-chromosome-%%-GO:0005657-&&-replication fork-%%-GO:0005737-&&-cytoplasm-%%-GO:0032389-&&-MutLalpha complex|molecular_function-&-1&-GO:0009378-&&-four-way junction helicase activity-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0061821-&&-telomeric D-loop binding-%%-GO:0000403-&&-Y-form DNA binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000405-&&-bubble DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0061749-&&-forked DNA-dependent helicase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0004527-&&-exonuclease activity-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0070337-&&-3'-flap-structured DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000400-&&-four-way junction DNA binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004386-&&-helicase activity-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0030145-&&-manganese ion binding-%%-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0043138-&&-3'-5' DNA helicase activity	G:9606:WRN				WRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WRN	0.40806223	0.28717949	42	4	FALSE	WRN	WRN	238.675	0	41	0	0.75823224	FALSE	1	WRN	77416	0.0685973
788891	taxon:9606	2.54986608	8.29E-05	176666	1902	XPA, DNA damage recognition and repair factor	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006284-&&-base-excision repair-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:1901255-&&-nucleotide-excision repair involved in interstrand cross-link repair-%%-GO:0009636-&&-response to toxic substance-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005737-&&-cytoplasm-%%-GO:0000110-&&-nucleotide-excision repair factor 1 complex-%%-GO:0005662-&&-DNA replication factor A complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:XPA	XPA	TRUE	KEGG-&-1&-hsa03420-&&-Nucleotide excision repair-%%-hsa01524-&&-Platinum drug resistance	XPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPA	0.39217746	0.1126597	42	4	FALSE	XPA	XPA	151.1428571	0	42	0	0.74168899	FALSE	0	XPA	123474	0.05262154
789224	taxon:9606	2.40995746	7.52E-05	175967	1902	tyrosyl-tRNA synthetase	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0007165-&&-signal transduction-%%-GO:0006437-&&-tyrosyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0017101-&&-aminoacyl-tRNA synthetase multienzyme complex-%%-GO:0005615-&&-extracellular space-%%-GO:0016604-&&-nuclear body-%%-GO:0017102-&&-methionyl glutamyl tRNA synthetase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0005153-&&-interleukin-8 receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004831-&&-tyrosine-tRNA ligase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004871-&&-signal transducer activity	G:9606:YARS			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	YARS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YARS	0.41494508	0.15214866	42	4	FALSE	YARS	YARS	251.7380952	0	42	0	0.76500709	FALSE	0	YARS	146352	0.06760318
789238	taxon:9606	2.45627856	9.90E-05	175925	1902	cyclin dependent kinase 13	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0030097-&&-hemopoiesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0007275-&&-multicellular organism development-%%-GO:0016032-&&-viral process-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016607-&&-nuclear speck-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0002945-&&-cyclin K-CDK13 complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0019908-&&-nuclear cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004672-&&-protein kinase activity	G:9606:CDK13				CDK13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK13	0.40711995	0.12891986	42	4	FALSE	CDK13	CDK13	196.8809524	0	42	0	0.75728691	FALSE	0	CDK13	145100	0.0571318
789506	taxon:9606	2.73278714	1.26E-05	175315	1902	lysine demethylase 4A	gene	biological_process-&-1&-GO:0016577-&&-histone demethylation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0070544-&&-histone H3-K36 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0016032-&&-viral process-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005721-&&-pericentric heterochromatin|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0035064-&&-methylated histone binding-%%-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:KDM4A				KDM4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM4A	0.36592678	0.47307692	42	4	FALSE	KDM4A	KDM4A	244.125	0	41	0	0.71120214	FALSE	1	KDM4A	41280	0.13579577
789592	taxon:9606	2.52717819	5.54E-05	175105	1902	non-SMC condensin I complex subunit D2	gene	biological_process-&-1&-GO:0051304-&&-chromosome separation-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0051301-&&-cell division-%%-GO:0010032-&&-meiotic chromosome condensation|cellular_component-&-1&-GO:0000796-&&-condensin complex-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0000799-&&-nuclear condensin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000793-&&-condensed chromosome-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0000797-&&-condensin core heterodimer-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding	G:9606:NCAPD2				NCAPD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPD2	0.39569825	0.14401858	42	4	FALSE	NCAPD2	NCAPD2	184.8095238	0	42	0	0.7454703	FALSE	0	NCAPD2	110738	0.06129787
789654	taxon:9606	2.6483378	1.36E-04	174971	1902	DLC1 Rho GTPase activating protein	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0021575-&&-hindbrain morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0007165-&&-signal transduction-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0001843-&&-neural tube closure-%%-GO:0030900-&&-forebrain development-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0008289-&&-lipid binding	G:9606:DLC1				DLC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLC1	0.37759534	0.02439024	42	4	FALSE	DLC1	DLC1	100.6904762	0	42	0	0.72527703	FALSE	0	DLC1	163550	0.04496522
789727	taxon:9606	2.50716874	1.80E-04	174812	1902	BCL2 like 11	gene	biological_process-&-1&-GO:0048066-&&-developmental pigmentation-%%-GO:1902263-&&-apoptotic process involved in embryonic digit morphogenesis-%%-GO:0030879-&&-mammary gland development-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0007127-&&-meiosis I-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0046620-&&-regulation of organ growth-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048070-&&-regulation of developmental pigmentation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:2000271-&&-positive regulation of fibroblast apoptotic process-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0048563-&&-post-embryonic animal organ morphogenesis-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0035148-&&-tube formation-%%-GO:0043583-&&-ear development-%%-GO:0048536-&&-spleen development-%%-GO:0060154-&&-cellular process regulating host cell cycle in response to virus-%%-GO:0006915-&&-apoptotic process-%%-GO:0048538-&&-thymus development-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0060139-&&-positive regulation of apoptotic process by virus-%%-GO:0007420-&&-brain development-%%-GO:0001822-&&-kidney development-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0008584-&&-male gonad development-%%-GO:0043029-&&-T cell homeostasis|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0005515-&&-protein binding	G:9606:BCL2L11			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	BCL2L11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L11	0.39885628	0.12307692	42	4	FALSE	BCL2L11	BCL2L11	152.95	0	41	0	0.74880521	FALSE	1	BCL2L11	217684	0.04898237
789751	taxon:9606	2.58972743	7.00E-05	174768	1902	nucleotide binding protein 2	gene	biological_process-&-1&-GO:0016226-&&-iron-sulfur cluster assembly-%%-GO:0030030-&&-cell projection organization|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:NUBP2				NUBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUBP2	0.38614102	0.06968641	42	4	FALSE	NUBP2	NUBP2	115.6190476	0	42	0	0.73504543	FALSE	0	NUBP2	116086	0.04414493
789907	taxon:9606	2.67764298	4.19E-05	158006	1902	microtubule associated protein 1 light chain 3 gamma	gene	biological_process-&-1&-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0000932-&&-P-body-%%-GO:0012505-&&-endomembrane system-%%-GO:0005776-&&-autophagosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0005874-&&-microtubule-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:MAP1LC3C			KEGG-&-1&-hsa04216-&&-Ferroptosis	MAP1LC3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1LC3C	0.37346278	0.12195122	42	4	FALSE	MAP1LC3C	MAP1LC3C	82.97619048	0	42	0	0.72039284	FALSE	0	MAP1LC3C	65968	0.03983495
789908	taxon:9606	2.60705845	3.60E-05	174390	1902	ATP synthase, H+ transporting, mitochondrial Fo complex subunit G	gene	biological_process-&-1&-GO:0015986-&&-ATP synthesis coupled proton transport-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0000276-&&-mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism	G:9606:ATP5L			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa01100-&&-Metabolic pathways	ATP5L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5L	0.38357406	0.18699187	42	4	FALSE	ATP5L	ATP5L	124.0476191	0	42	0	0.73215692	FALSE	0	ATP5L	66976	0.04940239
790021	taxon:9606	2.78162912	7.15E-05	174086	1902	activating transcription factor 7	gene	biological_process-&-1&-GO:0016032-&&-viral process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:ATF7				ATF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF7	0.35950156	0.20897436	42	4	FALSE	ATF7	ATF7	70.8	0	41	0	0.70306181	FALSE	1	ATF7	66970	0.04779959
790093	taxon:9606	2.5905152	3.61E-05	173888	1902	proteasome activator subunit 4	gene	biological_process-&-1&-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0035093-&&-spermatogenesis, exchange of chromosomal proteins-%%-GO:0006281-&&-DNA repair-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0007275-&&-multicellular organism development-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005839-&&-proteasome core complex-%%-GO:1990111-&&-spermatoproteasome complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0016504-&&-peptidase activator activity	G:9606:PSME4			KEGG-&-1&-hsa03050-&&-Proteasome	PSME4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSME4	0.3860236	0.23344948	42	4	FALSE	PSME4	PSME4	195.0476191	0	42	0	0.73491413	FALSE	0	PSME4	73444	0.07464632
790220	taxon:9606	2.54939341	7.65E-05	173606	1902	myosin phosphatase Rho interacting protein	gene	cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:MPRIP				MPRIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPRIP	0.39225017	0.25512821	42	4	FALSE	MPRIP	MPRIP	208.3	0	41	0	0.74176776	FALSE	1	MPRIP	123590	0.07254441
790236	taxon:9606	2.57239641	3.83E-05	173559	1902	WW and C2 domain containing 1	gene	biological_process-&-1&-GO:0046621-&&-negative regulation of organ growth-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0016477-&&-cell migration-%%-GO:0035330-&&-regulation of hippo signaling-%%-GO:0032386-&&-regulation of intracellular transport-%%-GO:0035329-&&-hippo signaling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035331-&&-negative regulation of hippo signaling-%%-GO:0043410-&&-positive regulation of MAPK cascade|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:WWC1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	WWC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWC1	0.38874257	0.23461092	42	4	FALSE	WWC1	WWC1	225.0238095	0	42	0	0.73793393	FALSE	0	WWC1	98452	0.08230969
790398	taxon:9606	2.49487947	4.58E-05	173122	1902	enhancer of mRNA decapping 4	gene	biological_process-&-1&-GO:0031087-&&-deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EDC4			KEGG-&-1&-hsa03018-&&-RNA degradation	EDC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EDC4	0.40082097	0.20209059	42	4	FALSE	EDC4	EDC4	216.0238095	0	42	0	0.75085342	FALSE	0	EDC4	102566	0.06728972
790452	taxon:9606	2.55679849	6.21E-05	172812	1902	F-box protein 7	gene	biological_process-&-1&-GO:0010975-&&-regulation of neuron projection development-%%-GO:0040012-&&-regulation of locomotion-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0000422-&&-mitophagy-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0045620-&&-negative regulation of lymphocyte differentiation|cellular_component-&-1&-GO:1990038-&&-Lewy body corona-%%-GO:0097462-&&-Lewy neurite-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0097414-&&-classical Lewy body-%%-GO:0005634-&&-nucleus-%%-GO:1990037-&&-Lewy body core-%%-GO:0005829-&&-cytosol-%%-GO:0097409-&&-glial cytoplasmic inclusion-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019901-&&-protein kinase binding	G:9606:FBXO7				FBXO7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO7	0.39111412	0.11033682	42	4	FALSE	FBXO7	FBXO7	151.2857143	0	42	0	0.74053359	FALSE	0	FBXO7	102800	0.05372167
790571	taxon:9606	2.71451079	9.31E-05	172107	1902	mutL homolog 3	gene	biological_process-&-1&-GO:0008104-&&-protein localization-%%-GO:0006298-&&-mismatch repair-%%-GO:0007140-&&-male meiosis-%%-GO:0007130-&&-synaptonemal complex assembly-%%-GO:0007144-&&-female meiosis I-%%-GO:0007131-&&-reciprocal meiotic recombination|cellular_component-&-1&-GO:0005712-&&-chiasma-%%-GO:0001673-&&-male germ cell nucleus-%%-GO:0032300-&&-mismatch repair complex-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0003696-&&-satellite DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0019237-&&-centromeric DNA binding	G:9606:MLH3			KEGG-&-1&-hsa03430-&&-Mismatch repair	MLH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLH3	0.3683905	0.03974359	42	4	FALSE	MLH3	MLH3	74.125	0	41	0	0.7142482	FALSE	1	MLH3	113432	0.03997833
790616	taxon:9606	2.67118324	5.16E-05	171745	1902	proteasome maturation protein	gene	biological_process-&-1&-GO:0043248-&&-proteasome assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031090-&&-organelle membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:POMP			KEGG-&-1&-hsa03050-&&-Proteasome	POMP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POMP	0.37436593	0.28076923	42	4	FALSE	POMP	POMP	115.75	0	41	0	0.72146946	FALSE	1	POMP	68246	0.05456583
790807	taxon:9606	2.58153458	3.03E-05	171144	1902	CXXC finger protein 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0045322-&&-unmethylated CpG binding-%%-GO:0005515-&&-protein binding	G:9606:CXXC1				CXXC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXXC1	0.38736649	0.17653891	42	4	FALSE	CXXC1	CXXC1	193.5	0	42	0	0.7364109	FALSE	0	CXXC1	76568	0.07201362
790838	taxon:9606	2.62943123	6.56E-05	171002	1902	exosome component 1	gene	biological_process-&-1&-GO:0043488-&&-regulation of mRNA stability-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000176-&&-nuclear exosome (RNase complex)|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:EXOSC1			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC1	0.38031038	0.11962834	42	4	FALSE	EXOSC1	EXOSC1	111.5714286	0	42	0	0.72842813	FALSE	0	EXOSC1	88350	0.04689724
790945	taxon:9606	2.57302663	6.62E-05	170640	1902	nemo like kinase	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0050821-&&-protein stabilization-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0033136-&&-serine phosphorylation of STAT3 protein|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008134-&&-transcription factor binding	G:9606:NLK			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04520-&&-Adherens junction	NLK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLK	0.38864736	0.1	42	4	FALSE	NLK	NLK	132.325	0	41	0	0.7378289	FALSE	1	NLK	102952	0.04868324
791162	taxon:9606	2.54309122	9.79E-05	169852	1902	protein phosphatase 4 regulatory subunit 3A	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center	G:9606:PPP4R3A			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway	PPP4R3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP4R3A	0.39322223	0.06039489	42	4	FALSE	PPP4R3A	PPP4R3A	132.5	0	42	0	0.74281813	FALSE	0	PPP4R3A	128542	0.04525602
791177	taxon:9606	2.68252718	4.09E-05	169812	1902	centrosomal protein 72	gene	biological_process-&-1&-GO:0033566-&&-gamma-tubulin complex localization-%%-GO:1904779-&&-regulation of protein localization to centrosome-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007051-&&-spindle organization-%%-GO:0007099-&&-centriole replication|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CEP72				CEP72	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP72	0.3727828	0.15795587	42	4	FALSE	CEP72	CEP72	106.1666667	0	42	0	0.7195788	FALSE	0	CEP72	65356	0.05141795
791186	taxon:9606	2.57964393	4.47E-05	169795	1902	checkpoint with forkhead and ring finger domains	gene	biological_process-&-1&-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0019941-&&-modification-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031648-&&-protein destabilization-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:CHFR				CHFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHFR	0.3876504	0.1025641	42	4	FALSE	CHFR	CHFR	155.35	0	41	0	0.73672601	FALSE	1	CHFR	85552	0.05810558
791220	taxon:9606	2.68693871	1.14E-04	169692	1902	protein phosphatase 2 regulatory subunit Bdelta	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032502-&&-developmental process-%%-GO:0051301-&&-cell division-%%-GO:0010458-&&-exit from mitosis-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2R2D			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R2D	0.37217075	0.18234611	42	4	FALSE	PPP2R2D	PPP2R2D	107	0	42	0	0.71884355	FALSE	0	PPP2R2D	158614	0.05229467
791399	taxon:9606	2.58610367	1.62E-04	168788	1902	G protein subunit beta 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0021762-&&-substantia nigra development|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0004871-&&-signal transducer activity	G:9606:GNB4			KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB4	0.3866821	0.12078978	42	4	FALSE	GNB4	GNB4	189.9047619	0	42	0	0.73564939	FALSE	0	GNB4	260594	0.07195225
791967	taxon:9606	2.54766031	1.09E-04	182794	1902	annexin A11	gene	biological_process-&-1&-GO:0006909-&&-phagocytosis-%%-GO:0051301-&&-cell division-%%-GO:0051592-&&-response to calcium ion-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0042582-&&-azurophil granule-%%-GO:0005635-&&-nuclear envelope-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0042581-&&-specific granule-%%-GO:0016020-&&-membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:ANXA11				ANXA11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA11	0.39251701	0.09291521	42	4	FALSE	ANXA11	ANXA11	148.6904762	0	42	0	0.74205661	FALSE	0	ANXA11	154186	0.05129153
792002	taxon:9606	2.47219159	3.89E-05	182751	1902	B-cell CLL/lymphoma 3	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0045064-&&-T-helper 2 cell differentiation-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002268-&&-follicular dendritic cell differentiation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0048536-&&-spleen development-%%-GO:0045415-&&-negative regulation of interleukin-8 biosynthetic process-%%-GO:0010225-&&-response to UV-C-%%-GO:0042536-&&-negative regulation of tumor necrosis factor biosynthetic process-%%-GO:0051101-&&-regulation of DNA binding-%%-GO:0002315-&&-marginal zone B cell differentiation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002467-&&-germinal center formation-%%-GO:0009615-&&-response to virus-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0002455-&&-humoral immune response mediated by circulating immunoglobulin-%%-GO:0045082-&&-positive regulation of interleukin-10 biosynthetic process-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032996-&&-Bcl3-Bcl10 complex-%%-GO:0043234-&&-protein complex-%%-GO:0033257-&&-Bcl3/NF-kappaB2 complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0030496-&&-midbody-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:BCL3			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway	BCL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL3	0.40449939	0.21138211	42	4	FALSE	BCL3	BCL3	201.6190476	0	42	0	0.75463474	FALSE	0	BCL3	93366	0.06038689
792050	taxon:9606	2.65968174	6.79E-05	166300	1902	nuclear assembly factor 1 ribonucleoprotein	gene	biological_process-&-1&-GO:0000493-&&-box H/ACA snoRNP assembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:1904874-&&-positive regulation of telomerase RNA localization to Cajal body-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0090669-&&-telomerase RNA stabilization-%%-GO:0043489-&&-RNA stabilization-%%-GO:1905323-&&-telomerase holoenzyme complex assembly-%%-GO:0000454-&&-snoRNA guided rRNA pseudouridine synthesis-%%-GO:1904358-&&-positive regulation of telomere maintenance via telomere lengthening|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005732-&&-small nucleolar ribonucleoprotein complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NAF1				NAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAF1	0.37598484	0.05574913	42	4	FALSE	NAF1	NAF1	93.57142857	0	42	0	0.72338638	FALSE	0	NAF1	86288	0.04255342
792085	taxon:9606	2.761147	7.48E-04	182640	1902	C-C motif chemokine receptor 5 (gene/pseudogene)	gene	biological_process-&-1&-GO:0023052-&&-signaling-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0014808-&&-release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0006816-&&-calcium ion transport-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0030260-&&-entry into host cell-%%-GO:0006935-&&-chemotaxis-%%-GO:0019064-&&-fusion of virus membrane with host plasma membrane-%%-GO:0006954-&&-inflammatory response-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006968-&&-cellular defense response-%%-GO:0070723-&&-response to cholesterol-%%-GO:0006955-&&-immune response-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0003779-&&-actin binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0016493-&&-C-C chemokine receptor activity-%%-GO:0071791-&&-chemokine (C-C motif) ligand 5 binding-%%-GO:0004950-&&-chemokine receptor activity-%%-GO:0019957-&&-C-C chemokine binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity	G:9606:CCR5			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	CCR5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCR5	0.36216833	0.08333333	42	4	FALSE	CCR5	CCR5	67.525	0	41	0	0.7064755	FALSE	1	CCR5	1068536	0.0440157
792142	taxon:9606	2.49456436	5.51E-05	166141	1902	GADD45G interacting protein 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:1903862-&&-positive regulation of oxidative phosphorylation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GADD45GIP1				GADD45GIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GADD45GIP1	0.4008716	0.11149826	42	4	FALSE	GADD45GIP1	GADD45GIP1	228.9285714	0	42	0	0.75090594	FALSE	0	GADD45GIP1	132360	0.07151042
792166	taxon:9606	2.59807783	1.16E-04	166110	1902	leucine rich repeat and sterile alpha motif containing 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0098656-&&-anion transmembrane transport-%%-GO:0046755-&&-viral budding-%%-GO:0070086-&&-ubiquitin-dependent endocytosis-%%-GO:2000786-&&-positive regulation of autophagosome assembly-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006914-&&-autophagy-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0030163-&&-protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0034702-&&-ion channel complex|molecular_function-&-1&-GO:0005225-&&-volume-sensitive anion channel activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:LRSAM1				LRSAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRSAM1	0.38489994	0.09230769	42	4	FALSE	LRSAM1	LRSAM1	112.075	0	41	0	0.73365369	FALSE	1	LRSAM1	126810	0.04344199
792322	taxon:9606	2.69481645	4.41E-05	182239	1902	cofilin 2	gene	biological_process-&-1&-GO:0030042-&&-actin filament depolymerization-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0030043-&&-actin filament fragmentation-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0045214-&&-sarcomere organization-%%-GO:0030836-&&-positive regulation of actin filament depolymerization|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0016363-&&-nuclear matrix-%%-GO:0031674-&&-I band|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding	G:9606:CFL2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05133-&&-Pertussis	CFL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFL2	0.37108279	0.22307692	42	4	FALSE	CFL2	CFL2	123.625	0	41	0	0.71753059	FALSE	1	CFL2	78128	0.06249368
792521	taxon:9606	2.58405546	1.35E-04	181853	1902	calcium/calmodulin dependent protein kinase II delta	gene	biological_process-&-1&-GO:0001558-&&-regulation of cell growth-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:1901725-&&-regulation of histone deacetylase activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1902306-&&-negative regulation of sodium ion transmembrane transport-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:1901897-&&-regulation of relaxation of cardiac muscle-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007399-&&-nervous system development-%%-GO:1902514-&&-regulation of calcium ion transmembrane transport via high voltage-gated calcium channel-%%-GO:0060341-&&-regulation of cellular localization-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0010649-&&-regulation of cell communication by electrical coupling-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0051259-&&-protein oligomerization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0098901-&&-regulation of cardiac muscle cell action potential-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0086003-&&-cardiac muscle cell contraction-%%-GO:1901844-&&-regulation of cell communication by electrical coupling involved in cardiac conduction-%%-GO:0018107-&&-peptidyl-threonine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0034704-&&-calcium channel complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0042383-&&-sarcolemma-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0031432-&&-titin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0019871-&&-sodium channel inhibitor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:CAMK2D			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04740-&&-Olfactory transduction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04713-&&-Circadian entrainment-%%-hsa04217-&&-Necroptosis	CAMK2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK2D	0.3869886	0.06282051	42	4	FALSE	CAMK2D	CAMK2D	114.275	0	41	0	0.73599076	FALSE	1	CAMK2D	137310	0.04281156
792534	taxon:9606	2.48495352	1.05E-04	181846	1902	calpain 2	gene	biological_process-&-1&-GO:0016540-&&-protein autoprocessing-%%-GO:0006508-&&-proteolysis-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0007520-&&-myoblast fusion-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001824-&&-blastocyst development-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0000785-&&-chromatin-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0031143-&&-pseudopodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:CAPN2			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CAPN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPN2	0.40242201	0.12311266	42	4	FALSE	CAPN2	CAPN2	152.8809524	0	42	0	0.75250775	FALSE	0	CAPN2	137472	0.04691683
792738	taxon:9606	2.50370254	3.15E-05	181461	1902	dynein cytoplasmic 1 intermediate chain 2	gene	biological_process-&-1&-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0016032-&&-viral process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007018-&&-microtubule-based movement|cellular_component-&-1&-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding	G:9606:DYNC1I2			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome	DYNC1I2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC1I2	0.39940847	0.19047619	42	4	FALSE	DYNC1I2	DYNC1I2	189.5476191	0	42	0	0.74938291	FALSE	0	DYNC1I2	66494	0.05998342
792795	taxon:9606	2.47360958	9.12E-05	181358	1902	eukaryotic translation initiation factor 2B subunit alpha	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0051716-&&-cellular response to stimulus-%%-GO:0009749-&&-response to glucose-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006413-&&-translational initiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043434-&&-response to peptide hormone|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0042802-&&-identical protein binding	G:9606:EIF2B1			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2B1	0.40426752	0.11410256	42	4	FALSE	EIF2B1	EIF2B1	177.2	0	41	0	0.7543984	FALSE	1	EIF2B1	144234	0.05287571
792961	taxon:9606	2.49566724	8.93E-05	181080	1902	four and a half LIM domains 1	gene	biological_process-&-1&-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0007517-&&-muscle organ development-%%-GO:1901016-&&-regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding	G:9606:FHL1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway	FHL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHL1	0.40069444	0.09756098	42	4	FALSE	FHL1	FHL1	177.9047619	0	42	0	0.75072213	FALSE	0	FHL1	137114	0.05572728
792971	taxon:9606	2.45486056	3.38E-05	181067	1902	FK506 binding protein 3	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:FKBP3				FKBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP3	0.40735511	0.20325203	42	4	FALSE	FKBP3	FKBP3	206.2857143	0	42	0	0.75752324	FALSE	0	FKBP3	79248	0.05961327
793036	taxon:9606	2.71829211	7.20E-05	180859	1902	glutamate ionotropic receptor NMDA type subunit 2B	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007611-&&-learning or memory-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006810-&&-transport-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0060079-&&-excitatory postsynaptic potential|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005622-&&-intracellular-%%-GO:0009986-&&-cell surface-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0016594-&&-glycine binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004972-&&-NMDA glutamate receptor activity	G:9606:GRIN2B			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05010-&&-Alzheimer disease-%%-hsa04720-&&-Long-term potentiation-%%-hsa05030-&&-Cocaine addiction-%%-hsa05033-&&-Nicotine addiction-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05016-&&-Huntington disease-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRIN2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIN2B	0.36787805	0.1025641	42	4	FALSE	GRIN2B	GRIN2B	86.675	0	41	0	0.71361798	FALSE	1	GRIN2B	86418	0.04797672
793098	taxon:9606	2.49866078	6.58E-05	180733	1902	glioblastoma amplified sequence	gene	biological_process-&-1&-GO:0006754-&&-ATP biosynthetic process-%%-GO:0006119-&&-oxidative phosphorylation-%%-GO:2000984-&&-negative regulation of ATP citrate synthase activity|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GBAS				GBAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBAS	0.40021439	0.11382114	42	4	FALSE	GBAS	GBAS	163.7142857	0	42	0	0.7502232	FALSE	0	GBAS	110996	0.05142648
793332	taxon:9606	2.53206239	2.07E-04	180310	1902	hexokinase 2	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0051156-&&-glucose 6-phosphate metabolic process-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0072656-&&-maintenance of protein location in mitochondrion-%%-GO:0035795-&&-negative regulation of mitochondrial membrane permeability-%%-GO:0015758-&&-glucose transport-%%-GO:1904925-&&-positive regulation of mitophagy in response to mitochondrial depolarization-%%-GO:0007595-&&-lactation-%%-GO:0006096-&&-glycolytic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0046324-&&-regulation of glucose import-%%-GO:0046835-&&-carbohydrate phosphorylation|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004396-&&-hexokinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008865-&&-fructokinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004340-&&-glucokinase activity-%%-GO:0019158-&&-mannokinase activity-%%-GO:0005536-&&-glucose binding	G:9606:HK2	HK2	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00524-&&-Neomycin, kanamycin and gentamicin biosynthesis-%%-hsa04066-&&-HIF-1 signaling pathway	HK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HK2	0.39493498	0.04297329	42	4	FALSE	HK2	HK2	137.6904762	0	42	0	0.74465627	FALSE	0	HK2	237770	0.04630254
787143	taxon:9606	2.5142587	1.28E-04	179990	1902	LIM domain kinase 1	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:LIMK1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04810-&&-Regulation of actin cytoskeleton	LIMK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIMK1	0.39773155	0.09581646	41	4	FALSE	LIMK1	LIMK1	148.6923077	0	40	0	0.74762355	FALSE	1	LIMK1	159206	0.04823312
787414	taxon:9606	2.55664093	1.39E-04	179474	1902	necdin, MAGE family member	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001764-&&-neuron migration-%%-GO:0048675-&&-axon extension-%%-GO:0007399-&&-nervous system development-%%-GO:0071514-&&-genetic imprinting-%%-GO:0007413-&&-axonal fasciculation-%%-GO:0008347-&&-glial cell migration-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0003016-&&-respiratory system process-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0007417-&&-central nervous system development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0040008-&&-regulation of growth-%%-GO:0048871-&&-multicellular organismal homeostasis-%%-GO:0009791-&&-post-embryonic development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0043204-&&-perikaryon-%%-GO:0042995-&&-cell projection-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0043015-&&-gamma-tubulin binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NDN				NDN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDN	0.39113823	0.0391363	41	4	FALSE	NDN	NDN	128	0	40	0	0.74055984	FALSE	1	NDN	148882	0.04536629
787756	taxon:9606	2.64849535	2.90E-05	162451	1902	alkB homolog 3, alpha-ketoglutaratedependent dioxygenase	gene	biological_process-&-1&-GO:0006307-&&-DNA dealkylation involved in DNA repair-%%-GO:0035552-&&-oxidative single-stranded DNA demethylation-%%-GO:0035553-&&-oxidative single-stranded RNA demethylation-%%-GO:0006281-&&-DNA repair-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:1990930-&&-RNA N1-methyladenosine dioxygenase activity-%%-GO:0043734-&&-DNA-N1-methyladenine dioxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0031418-&&-L-ascorbic acid binding	G:9606:ALKBH3				ALKBH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALKBH3	0.37757287	0.07439024	41	4	FALSE	ALKBH3	ALKBH3	134.1463415	0	41	0	0.72525077	FALSE	0	ALKBH3	58132	0.05952304
787823	taxon:9606	2.49188593	5.25E-05	178747	1902	protein kinase C substrate 80K-H	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006491-&&-N-glycan processing|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005622-&&-intracellular-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0005509-&&-calcium ion binding	G:9606:PRKCSH			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PRKCSH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCSH	0.40130248	0.13536585	41	4	FALSE	PRKCSH	PRKCSH	183.5609756	0	41	0	0.75135234	FALSE	0	PRKCSH	92672	0.05704194
787865	taxon:9606	2.58326769	6.11E-05	178686	1902	prosaposin	gene	biological_process-&-1&-GO:0071310-&&-cellular response to organic substance-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006869-&&-lipid transport-%%-GO:0060742-&&-epithelial cell differentiation involved in prostate gland development-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0060736-&&-prostate gland growth-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0019216-&&-regulation of lipid metabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0008047-&&-enzyme activator activity	G:9606:PSAP			KEGG-&-1&-hsa04142-&&-Lysosome	PSAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSAP	0.38710661	0.07017544	41	4	FALSE	PSAP	PSAP	127.4102564	0	40	0	0.73612205	FALSE	1	PSAP	85892	0.04790442
787948	taxon:9606	2.50055144	4.73E-05	178526	1902	platelet activating factor acetylhydrolase 1b catalytic subunit 3	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0007420-&&-brain development-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0047179-&&-platelet-activating factor acetyltransferase activity-%%-GO:0004623-&&-phospholipase A2 activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003847-&&-1-alkyl-2-acetylglycerophosphocholine esterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:PAFAH1B3			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00565-&&-Ether lipid metabolism	PAFAH1B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAFAH1B3	0.39991179	0.10796221	41	4	FALSE	PAFAH1B3	PAFAH1B3	197.3846154	0	40	0	0.74990809	FALSE	1	PAFAH1B3	111696	0.06201757
788169	taxon:9606	2.54892075	2.11E-05	178132	1902	RAD52 homolog, DNA repair protein	gene	biological_process-&-1&-GO:0006310-&&-DNA recombination-%%-GO:2000819-&&-regulation of nucleotide-excision repair-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0000730-&&-DNA recombinase assembly-%%-GO:0010792-&&-DNA double-strand break processing involved in repair via single-strand annealing-%%-GO:0034599-&&-cellular response to oxidative stress|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:RAD52			KEGG-&-1&-hsa03440-&&-Homologous recombination	RAD52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD52	0.39232291	0.18083671	41	4	FALSE	RAD52	RAD52	192.4358974	0	40	0	0.74184654	FALSE	1	RAD52	50708	0.06710311
788502	taxon:9606	2.45344257	1.12E-04	177540	1902	sorting nexin 1	gene	biological_process-&-1&-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0016050-&&-vesicle organization-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0031623-&&-receptor internalization|cellular_component-&-1&-GO:0030905-&&-retromer, tubulation complex-%%-GO:0031901-&&-early endosome membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005768-&&-endosome-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030904-&&-retromer complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1990459-&&-transferrin receptor binding-%%-GO:1990460-&&-leptin receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:SNX1			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX1	0.40759055	0.14304993	41	4	FALSE	SNX1	SNX1	165.2307692	0	40	0	0.75775957	FALSE	1	SNX1	146348	0.04766345
788663	taxon:9606	2.74271309	1.86E-04	177232	1902	thrombospondin 1	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0010759-&&-positive regulation of macrophage chemotaxis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006955-&&-immune response-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051592-&&-response to calcium ion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0002581-&&-negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II-%%-GO:0032914-&&-positive regulation of transforming growth factor beta1 production-%%-GO:0043652-&&-engulfment of apoptotic cell-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0007155-&&-cell adhesion-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0010754-&&-negative regulation of cGMP-mediated signaling-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033574-&&-response to testosterone-%%-GO:2001027-&&-negative regulation of endothelial cell chemotaxis-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0002576-&&-platelet degranulation-%%-GO:0048266-&&-behavioral response to pain-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010748-&&-negative regulation of plasma membrane long-chain fatty acid transport-%%-GO:0030823-&&-regulation of cGMP metabolic process-%%-GO:0036066-&&-protein O-linked fucosylation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0009749-&&-response to glucose-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0006954-&&-inflammatory response-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010757-&&-negative regulation of plasminogen activation-%%-GO:0032570-&&-response to progesterone-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0016477-&&-cell migration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0010751-&&-negative regulation of nitric oxide mediated signal transduction-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0002605-&&-negative regulation of dendritic cell antigen processing and presentation-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0031091-&&-platelet alpha granule-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030141-&&-secretory granule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005577-&&-fibrinogen complex|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0070051-&&-fibrinogen binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0008201-&&-heparin binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0043394-&&-proteoglycan binding-%%-GO:0043236-&&-laminin binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0070052-&&-collagen V binding-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005178-&&-integrin binding	G:9606:THBS1	THBS1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04145-&&-Phagosome-%%-hsa04510-&&-Focal adhesion-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05144-&&-Malaria-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05165-&&-Human papillomavirus infection	THBS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THBS1	0.36460248	0.09146341	41	4	FALSE	THBS1	THBS1	61.97560976	0	41	0	0.70954782	FALSE	0	THBS1	151802	0.03720173
788822	taxon:9606	2.54718765	1.02E-04	176811	1902	ubiquitin conjugating enzyme E2 G2	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1904153-&&-negative regulation of retrograde protein transport, ER to cytosol-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0044257-&&-cellular protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:UBE2G2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05012-&&-Parkinson disease-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	UBE2G2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2G2	0.39258984	0.07422402	41	4	FALSE	UBE2G2	UBE2G2	140.9230769	0	40	0	0.74213539	FALSE	1	UBE2G2	129932	0.0489624
788858	taxon:9606	2.59933827	4.10E-05	176746	1902	VHL binding protein 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007017-&&-microtubule-based process-%%-GO:0007021-&&-tubulin complex assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005844-&&-polysome-%%-GO:0016272-&&-prefoldin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0015631-&&-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:VBP1				VBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VBP1	0.3847133	0.12073171	41	4	FALSE	VBP1	VBP1	127.1707317	0	41	0	0.73344362	FALSE	0	VBP1	70382	0.0496962
788931	taxon:9606	2.50386009	5.19E-05	176574	1902	dual specificity tyrosine phosphorylation regulated kinase 2	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0051534-&&-negative regulation of NFAT protein import into nucleus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007224-&&-smoothened signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:DYRK2				DYRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYRK2	0.39938334	0.1304878	41	4	FALSE	DYRK2	DYRK2	183.7317073	0	41	0	0.74935665	FALSE	0	DYRK2	94680	0.05832888
789003	taxon:9606	2.43327556	2.36E-05	176418	1902	poly(A) binding protein nuclear 1	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0006396-&&-RNA processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0016973-&&-poly(A)+ mRNA export from nucleus-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:1904247-&&-positive regulation of polynucleotide adenylyltransferase activity-%%-GO:0046778-&&-modification by virus of host mRNA processing-%%-GO:0006936-&&-muscle contraction-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0042405-&&-nuclear inclusion body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0070063-&&-RNA polymerase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:PABPN1			KEGG-&-1&-hsa05164-&&-Influenza A-%%-hsa03015-&&-mRNA surveillance pathway	PABPN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPN1	0.41096866	0.27804878	41	4	FALSE	PABPN1	PABPN1	298.5853659	0	41	0	0.76112074	FALSE	0	PABPN1	73154	0.08294987
789118	taxon:9606	2.40554593	5.98E-05	176167	1902	SNRPN upstream reading frame	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:SNURF				SNURF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNURF	0.41570605	0.10609756	41	4	FALSE	SNURF	SNURF	220.4878049	0	41	0	0.76574235	FALSE	0	SNURF	144872	0.05854177
789212	taxon:9606	2.59398141	8.43E-05	175988	1902	LIM domain only 4	gene	biological_process-&-1&-GO:0048538-&&-thymus development-%%-GO:0003281-&&-ventricular septum development-%%-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0021514-&&-ventral spinal cord interneuron differentiation-%%-GO:0021527-&&-spinal cord association neuron differentiation-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0001843-&&-neural tube closure-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0050865-&&-regulation of cell activation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0042659-&&-regulation of cell fate specification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:LMO4				LMO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMO4	0.38550777	0.07560976	41	4	FALSE	LMO4	LMO4	127.2195122	0	41	0	0.73433643	FALSE	0	LMO4	118116	0.04871505
789417	taxon:9606	2.69686466	1.29E-04	175525	1902	SLC9A3 regulator 2	gene	biological_process-&-1&-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0012505-&&-endomembrane system-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019902-&&-phosphatase binding	G:9606:SLC9A3R2			KEGG-&-1&-hsa04960-&&-Aldosterone-regulated sodium reabsorption	SLC9A3R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC9A3R2	0.37080096	0.03658537	41	4	FALSE	SLC9A3R2	SLC9A3R2	74.14634146	0	41	0	0.71718922	FALSE	0	SLC9A3R2	116106	0.03807595
789487	taxon:9606	2.43138491	5.85E-05	175359	1902	nucleoporin 155	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0000972-&&-transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery-%%-GO:0016925-&&-protein sumoylation-%%-GO:0086014-&&-atrial cardiac muscle cell action potential-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0036228-&&-protein targeting to nuclear inner membrane-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016020-&&-membrane-%%-GO:0044611-&&-nuclear pore inner ring|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0017056-&&-structural constituent of nuclear pore	G:9606:NUP155			KEGG-&-1&-hsa03013-&&-RNA transport	NUP155	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP155	0.41128823	0.13414634	41	4	FALSE	NUP155	NUP155	282.3902439	0	41	0	0.76143585	FALSE	0	NUP155	159604	0.0784432
789523	taxon:9606	2.57649283	9.35E-05	175265	1902	nuclear receptor subfamily 1 group H member 3	gene	biological_process-&-1&-GO:0045723-&&-positive regulation of fatty acid biosynthetic process-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0051006-&&-positive regulation of lipoprotein lipase activity-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0060336-&&-negative regulation of interferon-gamma-mediated signaling pathway-%%-GO:0055092-&&-sterol homeostasis-%%-GO:0090341-&&-negative regulation of secretion of lysosomal enzymes-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0048550-&&-negative regulation of pinocytosis-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0032570-&&-response to progesterone-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0043031-&&-negative regulation of macrophage activation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:2000189-&&-positive regulation of cholesterol homeostasis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032376-&&-positive regulation of cholesterol transport-%%-GO:0090188-&&-negative regulation of pancreatic juice secretion-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0032369-&&-negative regulation of lipid transport|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0043235-&&-receptor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003677-&&-DNA binding-%%-GO:0032810-&&-sterol response element binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity	G:9606:NR1H3	NR1H3	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05160-&&-Hepatitis C-%%-hsa04931-&&-Insulin resistance-%%-hsa03320-&&-PPAR signaling pathway	NR1H3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR1H3	0.3881245	0.10731707	41	5	FALSE	NR1H3	NR1H3	125.2926829	0	41	0	0.73725119	FALSE	0	NR1H3	119218	0.0461114
789718	taxon:9606	2.73452025	7.17E-05	174831	1902	Rab acceptor 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:RABAC1				RABAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABAC1	0.36569486	0.048583	41	4	FALSE	RABAC1	RABAC1	69	0	40	0	0.71091329	FALSE	1	RABAC1	74068	0.03990926
789939	taxon:9606	2.55900425	1.49E-04	174297	1902	GIPC PDZ domain containing family member 1	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0014047-&&-glutamate secretion-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0006605-&&-protein targeting-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0032467-&&-positive regulation of cytokinesis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0043198-&&-dendritic shaft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005903-&&-brush border-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0012506-&&-vesicle membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005102-&&-receptor binding-%%-GO:0017022-&&-myosin binding-%%-GO:0045296-&&-cadherin binding	G:9606:GIPC1				GIPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIPC1	0.390777	0.04183536	41	4	FALSE	GIPC1	GIPC1	113.8205128	0	40	0	0.74016596	FALSE	1	GIPC1	144262	0.04074401
790267	taxon:9606	2.50953206	4.21E-05	173476	1902	activity dependent neuroprotector homeobox	gene	biological_process-&-1&-GO:0009743-&&-response to carbohydrate-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0044849-&&-estrous cycle-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0010035-&&-response to inorganic substance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033484-&&-nitric oxide homeostasis-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007614-&&-short-term memory-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0010835-&&-regulation of protein ADP-ribosylation|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding	G:9606:ADNP				ADNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADNP	0.39848066	0.14634146	41	4	FALSE	ADNP	ADNP	207.2195122	0	41	0	0.74841132	FALSE	0	ADNP	102738	0.06613314
790366	taxon:9606	2.49897589	9.87E-05	173211	1902	transportin 3	gene	biological_process-&-1&-GO:0035048-&&-splicing factor protein import into nucleus|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0042802-&&-identical protein binding	G:9606:TNPO3				TNPO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNPO3	0.40016392	0.0695122	41	4	FALSE	TNPO3	TNPO3	154.5853659	0	41	0	0.75017068	FALSE	0	TNPO3	161662	0.04858856
790381	taxon:9606	2.62202615	7.84E-05	173171	1902	DExD/H-box helicase 58	gene	biological_process-&-1&-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0045087-&&-innate immune response-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009597-&&-detection of virus-%%-GO:0039528-&&-cytoplasmic pattern recognition receptor signaling pathway in response to virus-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0009615-&&-response to virus-%%-GO:0032725-&&-positive regulation of granulocyte macrophage colony-stimulating factor production-%%-GO:0034344-&&-regulation of type III interferon production-%%-GO:0039529-&&-RIG-I signaling pathway|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003727-&&-single-stranded RNA binding	G:9606:DDX58			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B	DDX58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX58	0.38138445	0.14439946	41	4	FALSE	DDX58	DDX58	121.5384615	0	40	0	0.72966231	FALSE	1	DDX58	102028	0.05029381
790471	taxon:9606	2.51819757	1.40E-04	172757	1902	torsin 1A interacting protein 1	gene	biological_process-&-1&-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0071763-&&-nuclear membrane organization-%%-GO:0034504-&&-protein localization to nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005637-&&-nuclear inner membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005521-&&-lamin binding	G:9606:TOR1AIP1				TOR1AIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOR1AIP1	0.39710943	0.05487805	41	4	FALSE	TOR1AIP1	TOR1AIP1	169.5121951	0	41	0	0.74696707	FALSE	0	TOR1AIP1	204130	0.05522034
790908	taxon:9606	2.49503703	7.79E-05	170721	1902	RAB14, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0009790-&&-embryo development-%%-GO:0046907-&&-intracellular transport-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006895-&&-Golgi to endosome transport-%%-GO:0090382-&&-phagosome maturation-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0032456-&&-endocytic recycling-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005795-&&-Golgi stack-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0055037-&&-recycling endosome-%%-GO:0005770-&&-late endosome-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005929-&&-cilium-%%-GO:0005622-&&-intracellular-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0042175-&&-nuclear outer membrane-endoplasmic reticulum membrane network-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding-%%-GO:0031489-&&-myosin V binding	G:9606:RAB14			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway	RAB14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB14	0.40079566	0.07804878	41	4	FALSE	RAB14	RAB14	187.3414634	0	41	0	0.75082716	FALSE	0	RAB14	126294	0.05857782
790988	taxon:9606	2.61682685	3.20E-05	170484	1902	elongator acetyltransferase complex subunit 3	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0001764-&&-neuron migration-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0007417-&&-central nervous system development-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0033588-&&-Elongator holoenzyme complex-%%-GO:0005730-&&-nucleolus-%%-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0010484-&&-H3 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0051536-&&-iron-sulfur cluster binding-%%-GO:0008607-&&-phosphorylase kinase regulator activity-%%-GO:0010485-&&-H4 histone acetyltransferase activity	G:9606:ELP3				ELP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELP3	0.38214221	0.07682927	41	4	FALSE	ELP3	ELP3	187.8048781	0	41	0	0.73052886	FALSE	0	ELP3	80684	0.07538446
791051	taxon:9606	2.6831574	1.39E-04	170223	1902	HAUS augmin like complex subunit 7	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0031996-&&-thioesterase binding	G:9606:HAUS7				HAUS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS7	0.37269524	0.16219512	41	4	FALSE	HAUS7	HAUS7	94.97560976	0	41	0	0.71947377	FALSE	0	HAUS7	141788	0.04563184
791367	taxon:9606	2.52449976	4.98E-05	168957	1902	chromodomain helicase DNA binding protein 8	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048565-&&-digestive tract development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007420-&&-brain development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043044-&&-ATP-dependent chromatin remodeling-%%-GO:2000270-&&-negative regulation of fibroblast apoptotic process-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:CHD8			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	CHD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD8	0.39611808	0.12560976	41	4	FALSE	CHD8	CHD8	172.0243902	0	41	0	0.74591671	FALSE	0	CHD8	92564	0.05677901
791433	taxon:9606	2.62092327	2.80E-05	168667	1902	UPF3 regulator of nonsense transcripts homolog B (yeast)	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:UPF3B			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF3B	0.38154494	0.15789474	41	4	FALSE	UPF3B	UPF3B	160.0769231	0	40	0	0.72984612	FALSE	1	UPF3B	62208	0.06530612
791732	taxon:9606	2.68945959	6.99E-05	167139	1902	Ras association domain family member 5	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:1900180-&&-regulation of protein localization to nucleus-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0017016-&&-Ras GTPase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RASSF5			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence	RASSF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF5	0.37182191	0.09446694	41	5	FALSE	RASSF5	RASSF5	88.79487179	0	40	0	0.7184234	FALSE	1	RASSF5	85502	0.04453645
791788	taxon:9606	2.61257287	4.46E-05	166871	1902	DNA polymerase delta interacting protein 3	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0016973-&&-poly(A)+ mRNA export from nucleus-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0000346-&&-transcription export complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035145-&&-exon-exon junction complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:POLDIP3				POLDIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLDIP3	0.38276444	0.1097561	41	4	FALSE	POLDIP3	POLDIP3	166.6585366	0	41	0	0.73123786	FALSE	0	POLDIP3	91284	0.06626728
791912	taxon:9606	2.54860564	5.44E-05	182887	1902	aryl hydrocarbon receptor	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009410-&&-response to xenobiotic stimulus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001568-&&-blood vessel development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030888-&&-regulation of B cell proliferation-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0009636-&&-response to toxic substance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0034752-&&-cytosolic aryl hydrocarbon receptor complex-%%-GO:0034753-&&-nuclear aryl hydrocarbon receptor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004874-&&-aryl hydrocarbon receptor activity-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0035326-&&-enhancer binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding	G:9606:AHR	AHR	TRUE	KEGG-&-1&-hsa04659-&&-Th17 cell differentiation-%%-hsa04934-&&-Cushing syndrome	AHR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHR	0.39237141	0.18623482	41	4	FALSE	AHR	AHR	167.6153846	0	40	0	0.74189906	FALSE	1	AHR	90984	0.05786939
792136	taxon:9606	2.59240586	5.74E-05	166148	1902	multiple coagulation factor deficiency 2	gene	biological_process-&-1&-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0015031-&&-protein transport-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:MCFD2				MCFD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCFD2	0.38574207	0.10365854	41	4	FALSE	MCFD2	MCFD2	127.7073171	0	41	0	0.73459902	FALSE	0	MCFD2	87306	0.04903358
792187	taxon:9606	2.49472192	1.42E-04	182461	1902	Rho GTPase activating protein 1	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:ARHGAP1				ARHGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP1	0.40084628	0.0782726	41	4	FALSE	ARHGAP1	ARHGAP1	152.5641026	0	40	0	0.75087968	FALSE	1	ARHGAP1	168360	0.04756642
792426	taxon:9606	2.54041279	9.45E-05	182040	1902	solute carrier family 25 member 10	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0071422-&&-succinate transmembrane transport-%%-GO:1902358-&&-sulfate transmembrane transport-%%-GO:0006835-&&-dicarboxylic acid transport-%%-GO:0008272-&&-sulfate transport-%%-GO:0006094-&&-gluconeogenesis-%%-GO:1902356-&&-oxaloacetate(2-) transmembrane transport-%%-GO:0070221-&&-sulfide oxidation, using sulfide:quinone oxidoreductase-%%-GO:0015709-&&-thiosulfate transport-%%-GO:0035435-&&-phosphate ion transmembrane transport-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0071423-&&-malate transmembrane transport-%%-GO:0015729-&&-oxaloacetate transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0015297-&&-antiporter activity-%%-GO:0015117-&&-thiosulfate transmembrane transporter activity-%%-GO:0015131-&&-oxaloacetate transmembrane transporter activity-%%-GO:0015141-&&-succinate transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:1901677-&&-phosphate transmembrane transporter activity-%%-GO:0005310-&&-dicarboxylic acid transmembrane transporter activity-%%-GO:0015140-&&-malate transmembrane transporter activity-%%-GO:0015116-&&-sulfate transmembrane transporter activity	G:9606:SLC25A10			KEGG-&-1&-hsa04964-&&-Proximal tubule bicarbonate reclamation	SLC25A10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A10	0.39363681	0.06097561	41	4	FALSE	SLC25A10	SLC25A10	164.2682927	0	41	0	0.74326453	FALSE	0	SLC25A10	206268	0.05609339
792475	taxon:9606	2.56782732	8.17E-05	181966	1902	BTB domain and CNC homolog 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000117-&&-regulation of transcription involved in G2/M transition of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006302-&&-double-strand break repair-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006310-&&-DNA recombination-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001206-&&-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0020037-&&-heme binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:BACH1				BACH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BACH1	0.38943429	0.1268556	41	4	FALSE	BACH1	BACH1	138.948718	0	40	0	0.73869545	FALSE	1	BACH1	113990	0.04992719
792671	taxon:9606	2.49424925	7.08E-05	181584	1902	death associated protein kinase 3	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043519-&&-regulation of myosin II filament organization-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0030182-&&-neuron differentiation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000910-&&-cytokinesis-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:2000145-&&-regulation of cell motility-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0016605-&&-PML body-%%-GO:0005884-&&-actin filament|molecular_function-&-1&-GO:0043522-&&-leucine zipper domain binding-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008140-&&-cAMP response element binding protein binding	G:9606:DAPK3			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05219-&&-Bladder cancer-%%-hsa05200-&&-Pathways in cancer	DAPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAPK3	0.40092224	0.15789474	41	4	FALSE	DAPK3	DAPK3	184.0512821	0	40	0	0.75095846	FALSE	1	DAPK3	112398	0.05707991
792793	taxon:9606	2.54167323	5.39E-05	164975	1902	WD repeat domain 36	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0006364-&&-rRNA processing-%%-GO:0001895-&&-retina homeostasis-%%-GO:0050896-&&-response to stimulus-%%-GO:0008150-&&-biological_process-%%-GO:0030516-&&-regulation of axon extension|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus-%%-GO:0034388-&&-Pwp2p-containing subcomplex of 90S preribosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:WDR36			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	WDR36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR36	0.39344161	0.23658537	41	4	FALSE	WDR36	WDR36	199.4390244	0	41	0	0.74305446	FALSE	0	WDR36	86740	0.06781334
792801	taxon:9606	2.55947692	9.10E-05	181351	1902	eukaryotic translation initiation factor 4E binding protein 1	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:1990928-&&-response to amino acid starvation-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030324-&&-lung development-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0002192-&&-IRES-dependent translational initiation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0031929-&&-TOR signaling-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0030371-&&-translation repressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:EIF4EBP1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa03013-&&-RNA transport-%%-hsa04218-&&-Cellular senescence-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	EIF4EBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4EBP1	0.39070483	0.09756098	41	4	FALSE	EIF4EBP1	EIF4EBP1	128.3414634	0	41	0	0.74008718	FALSE	0	EIF4EBP1	115404	0.04570455
792873	taxon:9606	2.51221049	5.34E-05	181246	1902	eukaryotic translation termination factor 1	gene	biological_process-&-1&-GO:0006415-&&-translational termination-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006479-&&-protein methylation-%%-GO:0006449-&&-regulation of translational termination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016149-&&-translation release factor activity, codon specific-%%-GO:0003723-&&-RNA binding-%%-GO:0003747-&&-translation release factor activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0008079-&&-translation termination factor activity	G:9606:ETF1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	ETF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETF1	0.39805582	0.07804878	41	4	FALSE	ETF1	ETF1	146.1707317	0	41	0	0.74796492	FALSE	0	ETF1	95188	0.04720387
793127	taxon:9606	2.68930203	2.66E-04	180677	1902	gap junction protein alpha 1	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006915-&&-apoptotic process-%%-GO:0007507-&&-heart development-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0015867-&&-ATP transport-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0006936-&&-muscle contraction-%%-GO:0051259-&&-protein oligomerization-%%-GO:2000987-&&-positive regulation of behavioral fear response-%%-GO:0046697-&&-decidualization-%%-GO:0016264-&&-gap junction assembly-%%-GO:0003158-&&-endothelium development-%%-GO:0009749-&&-response to glucose-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0003104-&&-positive regulation of glomerular filtration-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0002931-&&-response to ischemia-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0086014-&&-atrial cardiac muscle cell action potential-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0009268-&&-response to pH-%%-GO:0010644-&&-cell communication by electrical coupling-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0010232-&&-vascular transport-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0006810-&&-transport-%%-GO:0010652-&&-positive regulation of cell communication by chemical coupling-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction|cellular_component-&-1&-GO:0005916-&&-fascia adherens-%%-GO:0005886-&&-plasma membrane-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005771-&&-multivesicular body-%%-GO:0005764-&&-lysosome-%%-GO:0005922-&&-connexin complex-%%-GO:0005921-&&-gap junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0014704-&&-intercalated disc-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:1903763-&&-gap junction channel activity involved in cell communication by electrical coupling-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005243-&&-gap junction channel activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0015075-&&-ion transmembrane transporter activity-%%-GO:0071253-&&-connexin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0086075-&&-gap junction channel activity involved in cardiac conduction electrical coupling	G:9606:GJA1	GJA1	TRUE	KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	GJA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJA1	0.37184369	0.05128205	41	4	FALSE	GJA1	GJA1	89.35897436	0	40	0	0.71844966	FALSE	1	GJA1	237710	0.04445554
793293	taxon:9606	2.52733575	1.29E-04	180361	1902	hemoglobin subunit alpha 1	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005833-&&-hemoglobin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0031838-&&-haptoglobin-hemoglobin complex-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004601-&&-peroxidase activity-%%-GO:0020037-&&-heme binding-%%-GO:0031720-&&-haptoglobin binding	G:9606:HBA1	HBA1	TRUE	KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa05144-&&-Malaria	HBA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBA1	0.39567359	0.12280702	41	4	FALSE	HBA1	HBA1	179.4102564	0	40	0	0.74544404	FALSE	1	HBA1	200922	0.05988326
793294	taxon:9606	2.52733575	1.29E-04	180360	1902	hemoglobin subunit alpha 2	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005833-&&-hemoglobin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0031838-&&-haptoglobin-hemoglobin complex-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004601-&&-peroxidase activity-%%-GO:0020037-&&-heme binding-%%-GO:0031720-&&-haptoglobin binding	G:9606:HBA2			KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa05144-&&-Malaria	HBA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBA2	0.39567359	0.12280702	41	4	FALSE	HBA2	HBA2	179.4102564	0	40	0	0.74544404	FALSE	1	HBA2	200922	0.05988326
787075	taxon:9606	2.58752166	4.57E-04	180113	1902	insulin like growth factor binding protein 3	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0044342-&&-type B pancreatic cell proliferation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0001649-&&-osteoblast differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0016942-&&-insulin-like growth factor binding protein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0042567-&&-insulin-like growth factor ternary complex|molecular_function-&-1&-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0005520-&&-insulin-like growth factor binding-%%-GO:0008160-&&-protein tyrosine phosphatase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001968-&&-fibronectin binding	G:9606:IGFBP3	IGFBP3	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04218-&&-Cellular senescence	IGFBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP3	0.38647019	0.05384615	40	4	FALSE	IGFBP3	IGFBP3	105.3	0	40	0	0.73541306	FALSE	0	IGFBP3	453110	0.04038831
787425	taxon:9606	2.53332283	6.76E-05	179458	1902	lymphocyte cytosolic protein 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050663-&&-cytokine secretion-%%-GO:0006955-&&-immune response-%%-GO:0045576-&&-mast cell activation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005911-&&-cell-cell junction-%%-GO:0036398-&&-TCR signalosome-%%-GO:0044853-&&-plasma membrane raft|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:LCP2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	LCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCP2	0.39473848	0.29615385	40	5	FALSE	LCP2	LCP2	162.45	0	40	0	0.7444462	FALSE	0	LCP2	99582	0.05485478
787489	taxon:9606	2.53710414	7.45E-05	179344	1902	MLLT3, super elongation complex subunit	gene	biological_process-&-1&-GO:0007379-&&-segment specification-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MLLT3			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	MLLT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLLT3	0.39415016	0.13086771	40	4	FALSE	MLLT3	MLLT3	150.3421053	0	39	0	0.74381598	FALSE	1	MLLT3	109028	0.05092659
787503	taxon:9606	2.86466047	6.38E-04	179331	1902	matrix metallopeptidase 9	gene	biological_process-&-1&-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:2001258-&&-negative regulation of cation channel activity-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0001503-&&-ossification-%%-GO:0006508-&&-proteolysis-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0051549-&&-positive regulation of keratinocyte migration-%%-GO:1900122-&&-positive regulation of receptor binding-%%-GO:2001268-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001501-&&-skeletal system development-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007566-&&-embryo implantation-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0043388-&&-positive regulation of DNA binding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005518-&&-collagen binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0042802-&&-identical protein binding	G:9606:MMP9	MMP9	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway	MMP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP9	0.34908151	0.04694168	40	4	FALSE	MMP9	MMP9	36.26315789	0	39	0	0.68922326	FALSE	1	MMP9	663858	0.03466354
787510	taxon:9606	2.63667875	1.10E-04	179312	1902	MOS proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0051296-&&-establishment of meiotic spindle orientation-%%-GO:1902103-&&-negative regulation of metaphase/anaphase transition of meiotic cell cycle-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0006325-&&-chromatin organization-%%-GO:0043410-&&-positive regulation of MAPK cascade|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MOS			KEGG-&-1&-hsa04114-&&-Oocyte meiosis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	MOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOS	0.37926501	0.07051282	40	4	FALSE	MOS	MOS	107.025	0	40	0	0.72722021	FALSE	0	MOS	130880	0.04602371
787523	taxon:9606	2.42382228	3.02E-05	179261	1902	myosin IB	gene	biological_process-&-1&-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016459-&&-myosin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0030175-&&-filopodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0010008-&&-endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005903-&&-brush border|molecular_function-&-1&-GO:0000146-&&-microfilament motor activity-%%-GO:0051015-&&-actin filament binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding	G:9606:MYO1B				MYO1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO1B	0.4125715	0.26666667	40	4	FALSE	MYO1B	MYO1B	289.2	0	40	0	0.76269629	FALSE	0	MYO1B	111472	0.07908917
787547	taxon:9606	2.53489838	4.25E-05	179215	1902	protein phosphatase 2 regulatory subunit Bbeta	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0032502-&&-developmental process-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:PPP2R2B			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R2B	0.39449313	0.21538462	40	4	FALSE	PPP2R2B	PPP2R2B	176.325	0	40	0	0.7441836	FALSE	0	PPP2R2B	70726	0.05907035
787562	taxon:9606	2.75642036	5.80E-05	179178	1902	NADH:ubiquinone oxidoreductase subunit A8	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFA8			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA8	0.36278937	0.23974359	40	4	FALSE	NDUFA8	NDUFA8	74.925	0	40	0	0.70726327	FALSE	0	NDUFA8	71510	0.0460899
787723	taxon:9606	2.69008981	4.56E-05	178869	1902	DNA polymerase beta	gene	biological_process-&-1&-GO:0006286-&&-base-excision repair, base-free sugar-phosphate removal-%%-GO:0006284-&&-base-excision repair-%%-GO:0048535-&&-lymph node development-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007568-&&-aging-%%-GO:0071707-&&-immunoglobulin heavy chain V-D-J recombination-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0006287-&&-base-excision repair, gap-filling-%%-GO:0045471-&&-response to ethanol-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0006288-&&-base-excision repair, DNA ligation-%%-GO:0006954-&&-inflammatory response-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0006281-&&-DNA repair-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0048536-&&-spleen development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0016829-&&-lyase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity	G:9606:POLB			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	POLB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLB	0.3717348	0.12307692	40	4	FALSE	POLB	POLB	111.9	0	40	0	0.71831837	FALSE	0	POLB	73388	0.05555417
787733	taxon:9606	2.62927367	1.11E-04	178857	1902	RNA polymerase II subunit F	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR2F			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2F	0.38033317	0.25384615	40	4	FALSE	POLR2F	POLR2F	102.325	0	40	0	0.72845439	FALSE	0	POLR2F	111414	0.04296382
787966	taxon:9606	2.49992122	8.14E-05	178494	1902	pyruvate carboxylase	gene	biological_process-&-1&-GO:0044791-&&-positive regulation by host of viral release from host cell-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0019074-&&-viral RNA genome packaging|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0009374-&&-biotin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004075-&&-biotin carboxylase activity-%%-GO:0004736-&&-pyruvate carboxylase activity	G:9606:PC			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism	PC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PC	0.4000126	0.16923077	40	4	FALSE	PC	PC	182.775	0	40	0	0.75001313	FALSE	0	PC	129130	0.0575717
788002	taxon:9606	2.7364109	5.36E-05	178427	1902	3-phosphoinositide dependent protein kinase 1	gene	biological_process-&-1&-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0010594-&&-regulation of endothelial cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0003323-&&-type B pancreatic cell development-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030168-&&-platelet activation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0016477-&&-cell migration-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0010518-&&-positive regulation of phospholipase activity-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0016020-&&-membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0043274-&&-phospholipase binding-%%-GO:0004676-&&-3-phosphoinositide-dependent protein kinase activity-%%-GO:0016004-&&-phospholipase activator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:PDPK1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04510-&&-Focal adhesion-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04660-&&-T cell receptor signaling pathway	PDPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDPK1	0.36544219	0.03846154	40	4	FALSE	PDPK1	PDPK1	72.625	0	40	0	0.71059818	FALSE	0	PDPK1	60700	0.04240023
788039	taxon:9606	2.69355601	9.62E-05	178316	1902	ribulose-5-phosphate-3-epimerase	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0019323-&&-pentose catabolic process-%%-GO:0044262-&&-cellular carbohydrate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0009052-&&-pentose-phosphate shunt, non-oxidative branch|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004750-&&-ribulose-phosphate 3-epimerase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:RPE			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00030-&&-Pentose phosphate pathway	RPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPE	0.37125643	0.04694168	40	4	FALSE	RPE	RPE	95.42105263	0	39	0	0.71774066	FALSE	1	RPE	109114	0.04859954
788094	taxon:9606	2.53757681	7.71E-05	178249	1902	phosphoglucomutase 1	gene	biological_process-&-1&-GO:0019388-&&-galactose catabolic process-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006096-&&-glycolytic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004614-&&-phosphoglucomutase activity	G:9606:PGM1			KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00230-&&-Purine metabolism-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00030-&&-Pentose phosphate pathway	PGM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGM1	0.39407674	0.16282051	40	4	FALSE	PGM1	PGM1	134.475	0	40	0	0.7437372	FALSE	0	PGM1	104034	0.04550761
788227	taxon:9606	2.64156294	9.46E-05	145283	1902	ARMCX5-GPRASP2 readthrough	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0005515-&&-protein binding	G:9606:ARMCX5-GPRASP2				ARMCX5-GPRASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARMCX5-GPRASP2	0.37856376	0.04230769	40	4	FALSE	ARMCX5-GPRASP2	ARMCX5-GPRASP2	102.25	0	40	0	0.72640618	FALSE	0	ARMCX5-GPRASP2	119356	0.04424577
788323	taxon:9606	2.72727273	1.12E-04	177881	1902	mitogen-activated protein kinase 12	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0007517-&&-muscle organ development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0051149-&&-positive regulation of muscle cell differentiation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAPK12			KEGG-&-1&-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK12	0.36666667	0.04694168	40	5	FALSE	MAPK12	MAPK12	72.05263158	0	39	0	0.71212121	FALSE	1	MAPK12	110006	0.04084414
788407	taxon:9606	2.61792973	1.19E-04	177724	1902	syntaxin 5	gene	biological_process-&-1&-GO:0048278-&&-vesicle docking-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006906-&&-vesicle fusion-%%-GO:0090166-&&-Golgi disassembly-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048280-&&-vesicle fusion with Golgi apparatus-%%-GO:0042147-&&-retrograde transport, endosome to Golgi|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0005484-&&-SNAP receptor activity	G:9606:STX5			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport	STX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX5	0.38198122	0.11923077	40	4	FALSE	STX5	STX5	103.55	0	40	0	0.73034504	FALSE	0	STX5	139652	0.04242207
788613	taxon:9606	2.50701119	3.07E-05	177307	1902	thymine DNA glycosylase	gene	biological_process-&-1&-GO:0006284-&&-base-excision repair-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009790-&&-embryo development-%%-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0035511-&&-oxidative DNA demethylation-%%-GO:0006298-&&-mismatch repair-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0080111-&&-DNA demethylation-%%-GO:0006285-&&-base-excision repair, AP site formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045008-&&-depyrimidination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0032183-&&-SUMO binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0030983-&&-mismatched DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004844-&&-uracil DNA N-glycosylase activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0008263-&&-pyrimidine-specific mismatch base pair DNA N-glycosylase activity	G:9606:TDG			KEGG-&-1&-hsa03410-&&-Base excision repair	TDG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TDG	0.39888135	0.22759602	40	4	FALSE	TDG	TDG	196.3421053	0	39	0	0.74883147	FALSE	1	TDG	72102	0.06220399
788666	taxon:9606	2.81187963	2.72E-04	177230	1902	thrombospondin 3	gene	biological_process-&-1&-GO:0007160-&&-cell-matrix adhesion-%%-GO:0043931-&&-ossification involved in bone maturation-%%-GO:0060346-&&-bone trabecula formation-%%-GO:0003417-&&-growth plate cartilage development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0008201-&&-heparin binding	G:9606:THBS3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04145-&&-Phagosome-%%-hsa04510-&&-Focal adhesion-%%-hsa05144-&&-Malaria-%%-hsa05165-&&-Human papillomavirus infection	THBS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THBS3	0.355634	0.00995733	40	4	FALSE	THBS3	THBS3	53.52631579	0	39	0	0.69802006	FALSE	1	THBS3	390186	0.04249544
788671	taxon:9606	2.5720813	7.22E-05	177223	1902	T-cell lymphoma invasion and metastasis 1	gene	biological_process-&-1&-GO:0072657-&&-protein localization to membrane-%%-GO:0006915-&&-apoptotic process-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:1905274-&&-regulation of modification of postsynaptic actin cytoskeleton-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:2000050-&&-regulation of non-canonical Wnt signaling pathway-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:1904268-&&-positive regulation of Schwann cell chemotaxis-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:1904338-&&-regulation of dopaminergic neuron differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1990138-&&-neuron projection extension-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0098989-&&-NMDA selective glutamate receptor signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0042220-&&-response to cocaine-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0044304-&&-main axon-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0044295-&&-axonal growth cone-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005911-&&-cell-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0019900-&&-kinase binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0048365-&&-Rac GTPase binding	G:9606:TIAM1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	TIAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIAM1	0.3887902	0.09246088	40	4	FALSE	TIAM1	TIAM1	134.2368421	0	39	0	0.73798645	FALSE	1	TIAM1	102292	0.04950245
788704	taxon:9606	2.68678116	3.19E-05	160764	1902	male specific lethal 1 homolog	gene	biological_process-&-1&-GO:0043984-&&-histone H4-K16 acetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0072487-&&-MSL complex	G:9606:MSL1				MSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSL1	0.37219258	0.20512821	40	4	FALSE	MSL1	MSL1	192.85	0	40	0	0.71886981	FALSE	0	MSL1	78532	0.09280212
788772	taxon:9606	2.44446195	7.71E-05	176933	1902	cold shock domain containing E1	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070966-&&-nuclear-transcribed mRNA catabolic process, no-go decay|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0070937-&&-CRD-mediated mRNA stability complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSDE1				CSDE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSDE1	0.40908798	0.18205128	40	4	FALSE	CSDE1	CSDE1	243.25	0	40	0	0.75925634	FALSE	0	CSDE1	140738	0.06893424
788807	taxon:9606	2.72286119	4.88E-05	176833	1902	thymidylate synthetase	gene	biological_process-&-1&-GO:0034097-&&-response to cytokine-%%-GO:0097421-&&-liver regeneration-%%-GO:0051593-&&-response to folic acid-%%-GO:0008283-&&-cell proliferation-%%-GO:0019088-&&-immortalization of host cell by virus-%%-GO:0009636-&&-response to toxic substance-%%-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0007568-&&-aging-%%-GO:0045471-&&-response to ethanol-%%-GO:0051216-&&-cartilage development-%%-GO:0007623-&&-circadian rhythm-%%-GO:0019860-&&-uracil metabolic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0046078-&&-dUMP metabolic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0032570-&&-response to progesterone-%%-GO:0032259-&&-methylation-%%-GO:0048589-&&-developmental growth-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0016049-&&-cell growth-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0033189-&&-response to vitamin A-%%-GO:0006231-&&-dTMP biosynthetic process-%%-GO:0046683-&&-response to organophosphorus-%%-GO:0006417-&&-regulation of translation-%%-GO:0006235-&&-dTTP biosynthetic process|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0004799-&&-thymidylate synthase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0005542-&&-folic acid binding-%%-GO:0048037-&&-cofactor binding-%%-GO:0003729-&&-mRNA binding	G:9606:TYMS			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01523-&&-Antifolate resistance	TYMS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYMS	0.36726073	0.08392603	40	4	FALSE	TYMS	TYMS	89	0	39	0	0.71285647	FALSE	1	TYMS	61124	0.04863953
788849	taxon:9606	2.64471404	4.45E-05	176753	1902	lysine demethylase 6A	gene	biological_process-&-1&-GO:0071557-&&-histone H3-K27 demethylation-%%-GO:0072358-&&-cardiovascular system development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032525-&&-somite rostral/caudal axis specification-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0003016-&&-respiratory system process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0048570-&&-notochord morphogenesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0003007-&&-heart morphogenesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0071558-&&-histone demethylase activity (H3-K27 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity	G:9606:KDM6A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	KDM6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM6A	0.37811271	0.26282051	40	4	FALSE	KDM6A	KDM6A	208	0	40	0	0.72588099	FALSE	0	KDM6A	97562	0.0894239
788850	taxon:9606	2.57995904	1.84E-04	176754	1902	utrophin	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0007517-&&-muscle organ development-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0006936-&&-muscle contraction-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0005886-&&-plasma membrane-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031527-&&-filopodium membrane-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0042383-&&-sarcolemma-%%-GO:0070938-&&-contractile ring-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding	G:9606:UTRN				UTRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTRN	0.38760305	0.0625889	40	4	FALSE	UTRN	UTRN	141.7894737	0	39	0	0.73667349	FALSE	1	UTRN	211982	0.05266095
788992	taxon:9606	2.5671971	4.71E-05	176439	1902	myeloid leukemia factor 2	gene	biological_process-&-1&-GO:0006952-&&-defense response|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MLF2				MLF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLF2	0.38952989	0.13589744	40	4	FALSE	MLF2	MLF2	143.1	0	40	0	0.73880048	FALSE	0	MLF2	88238	0.0516426
788998	taxon:9606	2.60296203	1.82E-05	176429	1902	high mobility group AT-hook 2	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000685-&&-positive regulation of cellular response to X-ray-%%-GO:0006284-&&-base-excision repair-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0040008-&&-regulation of growth-%%-GO:0090402-&&-oncogene-induced cell senescence-%%-GO:2001038-&&-regulation of cellular response to drug-%%-GO:0010564-&&-regulation of cell cycle process-%%-GO:0006325-&&-chromatin organization-%%-GO:0031052-&&-chromosome breakage-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007275-&&-multicellular organism development-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0030261-&&-chromosome condensation-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0031507-&&-heterochromatin assembly-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035978-&&-histone H2A-S139 phosphorylation-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0045869-&&-negative regulation of single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003131-&&-mesodermal-endodermal cell signaling-%%-GO:0009615-&&-response to virus-%%-GO:2001033-&&-negative regulation of double-strand break repair via nonhomologous end joining-%%-GO:0035986-&&-senescence-associated heterochromatin focus assembly-%%-GO:0035988-&&-chondrocyte proliferation-%%-GO:2000774-&&-positive regulation of cellular senescence-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0045444-&&-fat cell differentiation|cellular_component-&-1&-GO:0071141-&&-SMAD protein complex-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0035985-&&-senescence-associated heterochromatin focus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0008301-&&-DNA binding, bending-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0035501-&&-MH1 domain binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0000975-&&-regulatory region DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035500-&&-MH2 domain binding-%%-GO:0051575-&&-5'-deoxyribose-5-phosphate lyase activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0004677-&&-DNA-dependent protein kinase activity	G:9606:HMGA2	HMGA2	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer	HMGA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGA2	0.38417771	0.2	40	4	FALSE	HMGA2	HMGA2	228.25	0	40	0	0.73283966	FALSE	0	HMGA2	64792	0.08965043
789084	taxon:9606	2.59981093	6.93E-05	176222	1902	nuclear receptor subfamily 1 group I member 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042908-&&-xenobiotic transport-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0046618-&&-drug export-%%-GO:0042738-&&-exogenous drug catabolic process-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	G:9606:NR1I2	NR1I2	TRUE		NR1I2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR1I2	0.38464335	0.13798009	40	4	FALSE	NR1I2	NR1I2	130.1052632	0	39	0	0.73336484	FALSE	1	NR1I2	93240	0.05042669
789408	taxon:9606	2.58972743	5.52E-05	175546	1902	thyroid hormone receptor interactor 10	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0007154-&&-cell communication-%%-GO:0007165-&&-signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001891-&&-phagocytic cup-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:TRIP10			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	TRIP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP10	0.38614102	0.08392603	40	4	FALSE	TRIP10	TRIP10	128.2105263	0	39	0	0.73504543	FALSE	1	TRIP10	84912	0.04905497
789415	taxon:9606	2.62817079	9.79E-05	175531	1902	synaptosome associated protein 29	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0015031-&&-protein transport-%%-GO:0006887-&&-exocytosis-%%-GO:0016082-&&-synaptic vesicle priming-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016240-&&-autophagosome docking-%%-GO:0060271-&&-cilium assembly-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006903-&&-vesicle targeting|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0098793-&&-presynapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0020018-&&-ciliary pocket membrane-%%-GO:0005776-&&-autophagosome-%%-GO:0031201-&&-SNARE complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding	G:9606:SNAP29			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04140-&&-Autophagy - animal	SNAP29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAP29	0.38049278	0.07254623	40	4	FALSE	SNAP29	SNAP29	102.3157895	0	39	0	0.7286382	FALSE	1	SNAP29	110358	0.04258613
789504	taxon:9606	2.52796597	8.85E-05	175320	1902	TELO2 interacting protein 1	gene	biological_process-&-1&-GO:0032006-&&-regulation of TOR signaling|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031931-&&-TORC1 complex-%%-GO:0031932-&&-TORC2 complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TTI1			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	TTI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTI1	0.39557495	0.16794872	40	4	FALSE	TTI1	TTI1	161.625	0	40	0	0.74533901	FALSE	0	TTI1	131686	0.0537783
789526	taxon:9606	2.44540728	1.05E-04	175261	1902	secretory carrier membrane protein 3	gene	biological_process-&-1&-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0032526-&&-response to retinoic acid|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:SCAMP3				SCAMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAMP3	0.40892984	0.10641026	40	4	FALSE	SCAMP3	SCAMP3	201.7	0	40	0	0.75909879	FALSE	0	SCAMP3	176418	0.05736842
789703	taxon:9606	2.48495352	1.08E-04	174859	1902	importin 8	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:IPO8				IPO8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO8	0.40242201	0.09358974	40	4	FALSE	IPO8	IPO8	185.975	0	40	0	0.75250775	FALSE	0	IPO8	151964	0.05680012
789836	taxon:9606	2.54829053	5.36E-05	174543	1902	COP9 signalosome subunit 8	gene	biological_process-&-1&-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0000338-&&-protein deneddylation-%%-GO:0010387-&&-COP9 signalosome assembly-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COPS8				COPS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPS8	0.39241993	0.371266	40	4	FALSE	COPS8	COPS8	202.3421053	0	39	0	0.74195158	FALSE	1	COPS8	73358	0.07027294
789922	taxon:9606	2.56420356	1.33E-04	174353	1902	G protein subunit alpha 13	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0030168-&&-platelet activation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007165-&&-signal transduction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0031526-&&-brush border membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0031752-&&-D5 dopamine receptor binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:GNA13			KEGG-&-1&-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNA13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNA13	0.38998464	0.05897436	40	4	FALSE	GNA13	GNA13	128.575	0	40	0	0.73929941	FALSE	0	GNA13	168148	0.04636282
790081	taxon:9606	2.65385221	3.78E-05	173923	1902	proline synthetase cotranscribed homolog (bacterial)	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding	G:9606:PROSC				PROSC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PROSC	0.37681073	0.11923077	40	4	FALSE	PROSC	PROSC	105.125	0	40	0	0.72435796	FALSE	0	PROSC	58158	0.04705421
790298	taxon:9606	2.55947692	9.04E-05	173388	1902	ariadne RBR E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0015030-&&-Cajal body-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016604-&&-nuclear body-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0097413-&&-Lewy body-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ARIH1				ARIH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARIH1	0.39070483	0.10241821	40	4	FALSE	ARIH1	ARIH1	167.3157895	0	39	0	0.74008718	FALSE	1	ARIH1	124918	0.0594632
790340	taxon:9606	2.50370254	7.42E-05	173287	1902	KN motif and ankyrin repeat domains 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0070563-&&-negative regulation of vitamin D receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KANK2				KANK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KANK2	0.39940847	0.08108108	40	4	FALSE	KANK2	KANK2	163.1578947	0	39	0	0.74938291	FALSE	1	KANK2	117324	0.05181182
790426	taxon:9606	2.36395147	9.07E-05	173020	1902	argonaute 1, RISC catalytic component	gene	biological_process-&-1&-GO:0035279-&&-mRNA cleavage involved in gene silencing by miRNA-%%-GO:0090625-&&-mRNA cleavage involved in gene silencing by siRNA-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0010586-&&-miRNA metabolic process-%%-GO:0035196-&&-production of miRNAs involved in gene silencing by miRNA-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0035194-&&-posttranscriptional gene silencing by RNA-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0031054-&&-pre-miRNA processing-%%-GO:0035280-&&-miRNA loading onto RISC involved in gene silencing by miRNA-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000932-&&-P-body-%%-GO:0016442-&&-RISC complex-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0005844-&&-polysome-%%-GO:0035068-&&-micro-ribonucleoprotein complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:AGO1				AGO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGO1	0.42302053	0.17692308	40	4	FALSE	AGO1	AGO1	256.75	0	40	0	0.77267475	FALSE	0	AGO1	159064	0.06384606
790462	taxon:9606	2.630219	1.09E-04	172785	1902	dynamin 3	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0046847-&&-filopodium assembly-%%-GO:0007416-&&-synapse assembly-%%-GO:0098884-&&-postsynaptic neurotransmitter receptor internalization-%%-GO:0061025-&&-membrane fusion-%%-GO:0061002-&&-negative regulation of dendritic spine morphogenesis-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0016185-&&-synaptic vesicle budding from presynaptic endocytic zone membrane-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0031966-&&-mitochondrial membrane-%%-GO:0098844-&&-postsynaptic endocytic zone membrane-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0014069-&&-postsynaptic density-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0043083-&&-synaptic cleft-%%-GO:0043197-&&-dendritic spine-%%-GO:0005874-&&-microtubule-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0044327-&&-dendritic spine head-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0031802-&&-type 5 metabotropic glutamate receptor binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0031798-&&-type 1 metabotropic glutamate receptor binding-%%-GO:0005525-&&-GTP binding	G:9606:DNM3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04721-&&-Synaptic vesicle cycle	DNM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNM3	0.38019648	0.05512821	40	4	FALSE	DNM3	DNM3	103.125	0	40	0	0.72829683	FALSE	0	DNM3	133108	0.04385928
790470	taxon:9606	2.53127462	1.50E-04	172760	1902	golgi associated, gamma adaptin ear containing, ARF binding protein 1	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:1901998-&&-toxin transport-%%-GO:0061024-&&-membrane organization-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:GGA1			KEGG-&-1&-hsa04142-&&-Lysosome	GGA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GGA1	0.39505789	0.12944523	40	4	FALSE	GGA1	GGA1	141	0	39	0	0.74478756	FALSE	1	GGA1	159860	0.04746415
790651	taxon:9606	2.65022845	8.69E-05	171652	1902	egl-9 family hypoxia inducible factor 1	gene	biological_process-&-1&-GO:0032364-&&-oxygen homeostasis-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0051344-&&-negative regulation of cyclic-nucleotide phosphodiesterase activity-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0030821-&&-negative regulation of cAMP catabolic process-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0071731-&&-response to nitric oxide-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0031543-&&-peptidyl-proline dioxygenase activity-%%-GO:0031545-&&-peptidyl-proline 4-dioxygenase activity-%%-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0019899-&&-enzyme binding	G:9606:EGLN1			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	EGLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGLN1	0.37732596	0.14509246	40	4	FALSE	EGLN1	EGLN1	182.8157895	0	39	0	0.72496192	FALSE	1	EGLN1	151112	0.08096448
790701	taxon:9606	2.55648338	6.48E-05	171428	1902	anaphase promoting complex subunit 2	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0090129-&&-positive regulation of synapse maturation-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ANAPC2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC2	0.39116233	0.23589744	40	4	FALSE	ANAPC2	ANAPC2	147.85	0	40	0	0.7405861	FALSE	0	ANAPC2	103204	0.05204225
790703	taxon:9606	2.51835513	7.81E-05	171427	1902	CCR4-NOT transcription complex subunit 7	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0000290-&&-deadenylation-dependent decapping of nuclear-transcribed mRNA-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035195-&&-gene silencing by miRNA|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0030014-&&-CCR4-NOT complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity	G:9606:CNOT7			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT7	0.39708458	0.17435897	40	4	FALSE	CNOT7	CNOT7	225.775	0	40	0	0.74694081	FALSE	0	CNOT7	139506	0.07365416
790751	taxon:9606	2.48274775	4.02E-05	171334	1902	hydroxysteroid 17-beta dehydrogenase 12	gene	biological_process-&-1&-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0006703-&&-estrogen biosynthetic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004303-&&-estradiol 17-beta-dehydrogenase activity-%%-GO:0102341-&&-3-oxo-lignoceroyl-CoA reductase activity-%%-GO:0001968-&&-fibronectin binding-%%-GO:0102340-&&-3-oxo-behenoyl-CoA reductase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0016509-&&-long-chain-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0102339-&&-3-oxo-arachidoyl-CoA reductase activity-%%-GO:0102342-&&-3-oxo-cerotoyl-CoA reductase activity-%%-GO:0005518-&&-collagen binding	G:9606:HSD17B12			KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01100-&&-Metabolic pathways-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa01212-&&-Fatty acid metabolism	HSD17B12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B12	0.40277954	0.2474359	40	4	FALSE	HSD17B12	HSD17B12	188.1	0	40	0	0.75287537	FALSE	0	HSD17B12	94852	0.05716565
790765	taxon:9606	2.41562943	4.75E-05	171288	1902	DEAD-box helicase 47	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:DDX47				DDX47	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX47	0.41397078	0.17051282	40	4	FALSE	DDX47	DDX47	270.825	0	40	0	0.76406176	FALSE	0	DDX47	138382	0.07325487
790868	taxon:9606	2.48416575	4.33E-05	170830	1902	DGCR8, microprocessor complex subunit	gene	biological_process-&-1&-GO:0031053-&&-primary miRNA processing-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0031047-&&-gene silencing by RNA|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070877-&&-microprocessor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0070878-&&-primary miRNA binding-%%-GO:0004525-&&-ribonuclease III activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0020037-&&-heme binding-%%-GO:0005515-&&-protein binding	G:9606:DGCR8				DGCR8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DGCR8	0.40254963	0.15897436	40	4	FALSE	DGCR8	DGCR8	194.6	0	40	0	0.75263904	FALSE	0	DGCR8	83032	0.05944377
791136	taxon:9606	2.60957933	1.84E-05	169930	1902	DnaJ heat shock protein family (Hsp40) member A4	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0042026-&&-protein refolding|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DNAJA4				DNAJA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJA4	0.38320353	0.17780939	40	4	FALSE	DNAJA4	DNAJA4	163.131579	0	39	0	0.73173678	FALSE	1	DNAJA4	43946	0.0652055
791200	taxon:9606	2.5139436	6.28E-05	169743	1902	decapping mRNA 1A	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0031087-&&-deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0000290-&&-deadenylation-dependent decapping of nuclear-transcribed mRNA-%%-GO:1903608-&&-protein localization to cytoplasmic stress granule-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008047-&&-enzyme activator activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030234-&&-enzyme regulator activity-%%-GO:0042802-&&-identical protein binding	G:9606:DCP1A			KEGG-&-1&-hsa03018-&&-RNA degradation	DCP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCP1A	0.3977814	0.13655761	40	4	FALSE	DCP1A	DCP1A	160.8947368	0	39	0	0.74767607	FALSE	1	DCP1A	87072	0.05182617
791243	taxon:9606	2.70064597	1.80E-05	169545	1902	protein arginine methyltransferase 8	gene	biological_process-&-1&-GO:0019919-&&-peptidyl-arginine methylation, to asymmetrical-dimethyl arginine-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0034969-&&-histone arginine methylation-%%-GO:0016571-&&-histone methylation-%%-GO:0043393-&&-regulation of protein binding|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0035241-&&-protein-arginine omega-N monomethyltransferase activity-%%-GO:0035242-&&-protein-arginine omega-N asymmetric methyltransferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0042802-&&-identical protein binding	G:9606:PRMT8				PRMT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT8	0.37028178	0.11095306	40	4	FALSE	PRMT8	PRMT8	178.2631579	0	39	0	0.716559	FALSE	1	PRMT8	45090	0.09012858
791261	taxon:9606	2.57633528	1.05E-04	169465	1902	baculoviral IAP repeat containing 6	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060712-&&-spongiotrophoblast layer development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0060711-&&-labyrinthine layer development|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity	G:9606:BIRC6			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis	BIRC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC6	0.38814824	0.07539118	40	4	FALSE	BIRC6	BIRC6	134.7368421	0	39	0	0.73727745	FALSE	1	BIRC6	128890	0.04972274
791406	taxon:9606	2.49613991	9.75E-05	168765	1902	TBC1 domain family member 15	gene	biological_process-&-1&-GO:0043087-&&-regulation of GTPase activity-%%-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D15			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	TBC1D15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D15	0.40061857	0.08846154	40	4	FALSE	TBC1D15	TBC1D15	167.325	0	40	0	0.75064335	FALSE	0	TBC1D15	157180	0.05217765
791425	taxon:9606	2.64250827	6.49E-05	168698	1902	mitochondrial ribosomal protein L40	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005634-&&-nucleus-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MRPL40				MRPL40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL40	0.37842833	0.11025641	40	4	FALSE	MRPL40	MRPL40	113.775	0	40	0	0.72624862	FALSE	0	MRPL40	96588	0.04906169
791473	taxon:9606	2.50748385	7.74E-05	168489	1902	exocyst complex component 4	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0006903-&&-vesicle targeting-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0048341-&&-paraxial mesoderm formation-%%-GO:0006887-&&-exocytosis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000145-&&-exocyst-%%-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0032584-&&-growth cone membrane-%%-GO:0016020-&&-membrane-%%-GO:0045202-&&-synapse-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0017160-&&-Ral GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0030165-&&-PDZ domain binding	G:9606:EXOC4				EXOC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC4	0.39880616	0.1474359	40	4	FALSE	EXOC4	EXOC4	161.1	0	40	0	0.74875269	FALSE	0	EXOC4	130708	0.05113528
791498	taxon:9606	2.55522294	6.84E-05	168379	1902	praja ring finger ubiquitin ligase 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0030163-&&-protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:PJA1				PJA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PJA1	0.39135528	0.11095306	40	4	FALSE	PJA1	PJA1	154.8421053	0	39	0	0.74079618	FALSE	1	PJA1	96992	0.05463013
791595	taxon:9606	2.54009768	3.98E-05	167898	1902	GrpE like 1, mitochondrial	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0030150-&&-protein import into mitochondrial matrix|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0001405-&&-presequence translocase-associated import motor-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:GRPEL1				GRPEL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRPEL1	0.39368565	0.19061166	40	4	FALSE	GRPEL1	GRPEL1	172.7368421	0	39	0	0.74331705	FALSE	1	GRPEL1	75668	0.05874508
791659	taxon:9606	2.67953364	8.95E-05	167557	1902	cyclin L2	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:1901409-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CCNL2				CCNL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNL2	0.37319927	0.03974359	40	5	FALSE	CCNL2	CCNL2	89.6	0	40	0	0.72007773	FALSE	0	CCNL2	101410	0.04343066
791808	taxon:9606	2.64046006	8.76E-05	166779	1902	l(3)mbt-like 3 (Drosophila)	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:L3MBTL3				L3MBTL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-L3MBTL3	0.37872188	0.04978663	40	4	FALSE	L3MBTL3	L3MBTL3	117.4473684	0	39	0	0.72658999	FALSE	1	L3MBTL3	120028	0.05023001
791896	taxon:9606	2.52686308	6.48E-05	182912	1902	adaptor related protein complex 1 gamma 1 subunit	gene	biological_process-&-1&-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0043323-&&-positive regulation of natural killer cell degranulation-%%-GO:0090160-&&-Golgi to lysosome transport-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0032438-&&-melanosome organization-%%-GO:0035646-&&-endosome to melanosome transport-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030119-&&-AP-type membrane coat adaptor complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0055037-&&-recycling endosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0019894-&&-kinesin binding	G:9606:AP1G1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1G1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1G1	0.3957476	0.13940256	40	4	FALSE	AP1G1	AP1G1	143.1052632	0	39	0	0.74552282	FALSE	1	AP1G1	92996	0.04739808
792194	taxon:9606	2.61020955	3.88E-04	182449	1902	aryl hydrocarbon receptor nuclear translocator	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004874-&&-aryl hydrocarbon receptor activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017162-&&-aryl hydrocarbon receptor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:ARNT			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04934-&&-Cushing syndrome-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa04066-&&-HIF-1 signaling pathway	ARNT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARNT	0.383111	0.14509246	40	4	FALSE	ARNT	ARNT	135.2368421	0	39	0	0.73163174	FALSE	1	ARNT	468686	0.05388071
792265	taxon:9606	2.4874744	4.31E-05	182317	1902	cyclin dependent kinase 11B	gene	biological_process-&-1&-GO:0001558-&&-regulation of cell growth-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008283-&&-cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:CDK11B				CDK11B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK11B	0.40201419	0.14651494	40	4	FALSE	CDK11B	CDK11B	199.6842105	0	39	0	0.7520876	FALSE	1	CDK11B	84272	0.06130383
792357	taxon:9606	2.55916181	3.32E-05	182164	1902	ERCC excision repair 8, CSA ubiquitin ligase complex subunit	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0010165-&&-response to X-ray-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0009411-&&-response to UV-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0000109-&&-nucleotide-excision repair complex-%%-GO:0043234-&&-protein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003678-&&-DNA helicase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:ERCC8			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa03420-&&-Nucleotide excision repair	ERCC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC8	0.39075294	0.29487179	40	4	FALSE	ERCC8	ERCC8	183.2	0	40	0	0.7401397	FALSE	0	ERCC8	67442	0.06493265
792500	taxon:9606	2.64156294	9.46E-05	165519	1902	G protein-coupled receptor associated sorting protein 2	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0005515-&&-protein binding	G:9606:GPRASP2				GPRASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPRASP2	0.37856376	0.04230769	40	4	FALSE	GPRASP2	GPRASP2	102.25	0	40	0	0.72640618	FALSE	0	GPRASP2	119356	0.04424577
792565	taxon:9606	2.41389633	1.21E-04	181807	1902	carbonyl reductase 1	gene	biological_process-&-1&-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0017144-&&-drug metabolic process-%%-GO:0042373-&&-vitamin K metabolic process-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0004090-&&-carbonyl reductase (NADPH) activity-%%-GO:0047021-&&-15-hydroxyprostaglandin dehydrogenase (NADP+) activity-%%-GO:0050221-&&-prostaglandin-E2 9-reductase activity	G:9606:CBR1			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBR1	0.414268	0.12051282	40	4	FALSE	CBR1	CBR1	249.825	0	40	0	0.76435061	FALSE	0	CBR1	175462	0.06730458
792613	taxon:9606	2.57775327	5.00E-05	181717	1902	E2F transcription factor 4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0002064-&&-epithelial cell development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0044458-&&-motile cilium assembly-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008015-&&-blood circulation-%%-GO:1903251-&&-multi-ciliated epithelial cell differentiation-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0006884-&&-cell volume homeostasis-%%-GO:0098534-&&-centriole assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:1990841-&&-promoter-specific chromatin binding	G:9606:E2F4			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04218-&&-Cellular senescence-%%-hsa04350-&&-TGF-beta signaling pathway	E2F4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F4	0.38793472	0.16153846	40	4	FALSE	E2F4	E2F4	149.825	0	40	0	0.73704112	FALSE	0	E2F4	86230	0.05510486
792812	taxon:9606	2.48511108	8.71E-05	181330	1902	ELK1, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0009416-&&-response to light stimulus-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071774-&&-response to fibroblast growth factor-%%-GO:0071394-&&-cellular response to testosterone stimulus-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043679-&&-axon terminus-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ELK1	ELK1	TRUE	KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma	ELK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELK1	0.4023965	0.14366999	40	4	FALSE	ELK1	ELK1	185.2894737	0	39	0	0.75248149	FALSE	1	ELK1	128392	0.05676334
792968	taxon:9606	2.65999685	7.17E-05	181068	1902	FK506 binding protein 2	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding	G:9606:FKBP2				FKBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP2	0.37594029	0.12564103	40	4	FALSE	FKBP2	FKBP2	95.4	0	40	0	0.72333386	FALSE	0	FKBP2	90744	0.04391144
793022	taxon:9606	2.55837403	1.05E-04	180877	1902	growth factor receptor bound protein 7	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0034063-&&-stress granule assembly-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0042995-&&-cell projection-%%-GO:0005829-&&-cytosol-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding	G:9606:GRB7				GRB7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRB7	0.39087326	0.07948718	40	5	FALSE	GRB7	GRB7	140.825	0	40	0	0.74027099	FALSE	0	GRB7	126386	0.05024124
793023	taxon:9606	2.43595399	8.42E-05	180876	1902	growth factor receptor bound protein 10	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding	G:9606:GRB10			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	GRB10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRB10	0.41051678	0.22820513	40	4	FALSE	GRB10	GRB10	197.075	0	40	0	0.76067433	FALSE	0	GRB10	132300	0.05526648
787176	taxon:9606	2.39688042	1.13E-05	179919	1902	cell cycle associated protein 1	gene	biological_process-&-1&-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0017148-&&-negative regulation of translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0016020-&&-membrane-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CAPRIN1				CAPRIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPRIN1	0.41720897	0.27927928	39	4	FALSE	CAPRIN1	CAPRIN1	356.9189189	0	38	0	0.7671866	FALSE	1	CAPRIN1	57230	0.09333654
787246	taxon:9606	2.59287853	5.23E-05	179806	1902	interferon regulatory factor 7	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:2000110-&&-negative regulation of macrophage apoptotic process-%%-GO:0002819-&&-regulation of adaptive immune response-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0039530-&&-MDA-5 signaling pathway-%%-GO:0034127-&&-regulation of MyD88-independent toll-like receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0032608-&&-interferon-beta production-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034124-&&-regulation of MyD88-dependent toll-like receptor signaling pathway-%%-GO:0045351-&&-type I interferon biosynthetic process-%%-GO:0045655-&&-regulation of monocyte differentiation-%%-GO:0032607-&&-interferon-alpha production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0045087-&&-innate immune response-%%-GO:0009615-&&-response to virus-%%-GO:0019043-&&-establishment of viral latency|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:IRF7			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B	IRF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF7	0.38567175	0.14414414	39	4	FALSE	IRF7	IRF7	148.7297297	0	38	0	0.73452025	FALSE	1	IRF7	82864	0.0570317
787252	taxon:9606	2.53521349	3.33E-05	179796	1902	IL2 inducible T-cell kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0002250-&&-adaptive immune response-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0001816-&&-cytokine production-%%-GO:0007165-&&-signal transduction-%%-GO:0006968-&&-cellular defense response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0032609-&&-interferon-gamma production-%%-GO:0032633-&&-interleukin-4 production-%%-GO:0001865-&&-NK T cell differentiation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0042110-&&-T cell activation|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:ITK			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04660-&&-T cell receptor signaling pathway	ITK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITK	0.3944441	0.26576577	39	4	FALSE	ITK	ITK	177.1621622	0	38	0	0.74413109	FALSE	1	ITK	73132	0.05993307
787390	taxon:9606	2.51457381	9.08E-05	179515	1902	myosin VA	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0051643-&&-endoplasmic reticulum localization-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0030073-&&-insulin secretion-%%-GO:0030050-&&-vesicle transport along actin filament-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0006887-&&-exocytosis-%%-GO:0042438-&&-melanin biosynthetic process-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0042552-&&-myelination-%%-GO:0032402-&&-melanosome transport-%%-GO:0006810-&&-transport-%%-GO:0031987-&&-locomotion involved in locomotory behavior-%%-GO:0031585-&&-regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0050808-&&-synapse organization-%%-GO:0032252-&&-secretory granule localization-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0007601-&&-visual perception-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042759-&&-long-chain fatty acid biosynthetic process-%%-GO:0042476-&&-odontogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005884-&&-actin filament-%%-GO:0030426-&&-growth cone-%%-GO:0031982-&&-vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0001726-&&-ruffle-%%-GO:0055037-&&-recycling endosome-%%-GO:0043005-&&-neuron projection-%%-GO:0043025-&&-neuronal cell body-%%-GO:0032593-&&-insulin-responsive compartment-%%-GO:0016459-&&-myosin complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005770-&&-late endosome-%%-GO:0032433-&&-filopodium tip-%%-GO:0005777-&&-peroxisome-%%-GO:0005882-&&-intermediate filament-%%-GO:0042641-&&-actomyosin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005509-&&-calcium ion binding	G:9606:MYO5A				MYO5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO5A	0.3976817	0.18758435	39	4	FALSE	MYO5A	MYO5A	188.1538462	0	39	0	0.74757103	FALSE	0	MYO5A	134264	0.06094208
787554	taxon:9606	2.72916338	5.63E-05	179188	1902	methylthioadenosine phosphorylase	gene	biological_process-&-1&-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0006166-&&-purine ribonucleoside salvage-%%-GO:0019509-&&-L-methionine salvage from methylthioadenosine-%%-GO:0006738-&&-nicotinamide riboside catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0017061-&&-S-methyl-5-thioadenosine phosphorylase activity-%%-GO:0004645-&&-phosphorylase activity-%%-GO:0005515-&&-protein binding	G:9606:MTAP			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01100-&&-Metabolic pathways	MTAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTAP	0.36641265	0.09311741	39	4	FALSE	MTAP	MTAP	83.28205128	0	39	0	0.7118061	FALSE	0	MTAP	66622	0.04621083
787558	taxon:9606	2.5306444	4.21E-05	179183	1902	cytochrome c oxidase subunit II	gene		G:9606:COX2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	COX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COX2	0.39515627	0.20782726	39	4	FALSE	COX2	COX2	178.8205128	0	39	0	0.7448926	FALSE	0	COX2	79342	0.05996095
787578	taxon:9606	2.42429494	1.03E-04	179150	1902	developmentally regulated GTP binding protein 1	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding	G:9606:DRG1				DRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DRG1	0.41249106	0.1120108	39	4	FALSE	DRG1	DRG1	286.5384615	0	39	0	0.76261751	FALSE	0	DRG1	164166	0.07867709
787606	taxon:9606	2.52591776	1.16E-05	179108	1902	tonsoku-like, DNA repair protein	gene	biological_process-&-1&-GO:0031297-&&-replication fork processing-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor|cellular_component-&-1&-GO:0042555-&&-MCM complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0035101-&&-FACT complex-%%-GO:0005662-&&-DNA replication factor A complex|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:TONSL				TONSL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TONSL	0.39589571	0.43543544	39	4	FALSE	TONSL	TONSL	275.0810811	0	38	0	0.74568037	FALSE	1	TONSL	43272	0.09013142
787816	taxon:9606	2.4261856	6.94E-05	178749	1902	protein kinase D1	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0048193-&&-Golgi vesicle transport-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:2001044-&&-regulation of integrin-mediated signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0089700-&&-protein kinase D signaling-%%-GO:0007030-&&-Golgi organization-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1901727-&&-positive regulation of histone deacetylase activity-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0006954-&&-inflammatory response-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:0007165-&&-signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0001525-&&-angiogenesis-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0008283-&&-cell proliferation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PRKD1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion	PRKD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKD1	0.41216962	0.16816817	39	4	FALSE	PRKD1	PRKD1	211.7567568	0	38	0	0.7623024	FALSE	1	PRKD1	120892	0.0580803
787834	taxon:9606	2.48511108	9.66E-05	178736	1902	mitogen-activated protein kinase 11	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0098586-&&-cellular response to virus-%%-GO:0007165-&&-signal transduction-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:2001184-&&-positive regulation of interleukin-12 secretion-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0006950-&&-response to stress-%%-GO:0060044-&&-negative regulation of cardiac muscle cell proliferation-%%-GO:0051149-&&-positive regulation of muscle cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAPK11			KEGG-&-1&-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04611-&&-Platelet activation-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	MAPK11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK11	0.4023965	0.11740891	39	4	FALSE	MAPK11	MAPK11	172.7692308	0	39	0	0.75248149	FALSE	0	MAPK11	141492	0.05272265
787963	taxon:9606	2.56451867	1.00E-04	162112	1902	polymerase I and transcript release factor	gene	biological_process-&-1&-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042134-&&-rRNA primary transcript binding	G:9606:PTRF				PTRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTRF	0.38993672	0.12145749	39	4	FALSE	PTRF	PTRF	145.4871795	0	39	0	0.73924689	FALSE	0	PTRF	123814	0.05243872
788023	taxon:9606	2.69182291	9.02E-05	178369	1902	ring finger protein 5	gene	biological_process-&-1&-GO:0010507-&&-negative regulation of autophagy-%%-GO:0055085-&&-transmembrane transport-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0036503-&&-ERAD pathway-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0031648-&&-protein destabilization-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process-%%-GO:0009617-&&-response to bacterium-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0044390-&&-ubiquitin-like protein conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF5			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	RNF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF5	0.37149546	0.0990991	39	4	FALSE	RNF5	RNF5	110.2432432	0	38	0	0.71802952	FALSE	1	RNF5	115234	0.05586592
788504	taxon:9606	2.77170317	1.70E-04	177542	1902	syntrophin alpha 1	gene	biological_process-&-1&-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:1902083-&&-negative regulation of peptidyl-cysteine S-nitrosylation-%%-GO:1902305-&&-regulation of sodium ion transmembrane transport-%%-GO:0006936-&&-muscle contraction-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0043234-&&-protein complex-%%-GO:0005622-&&-intracellular-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016013-&&-syntrophin complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0042383-&&-sarcolemma-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0017080-&&-sodium channel regulator activity-%%-GO:0003779-&&-actin binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0044325-&&-ion channel binding	G:9606:SNTA1				SNTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNTA1	0.36078899	0.0148448	39	4	FALSE	SNTA1	SNTA1	51.53846154	0	39	0	0.70471614	FALSE	0	SNTA1	143976	0.03408506
788688	taxon:9606	2.57728061	5.83E-05	177187	1902	tropomodulin 1	gene	biological_process-&-1&-GO:0008344-&&-adult locomotory behavior-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0070307-&&-lens fiber cell development-%%-GO:0030239-&&-myofibril assembly-%%-GO:0051694-&&-pointed-end actin filament capping|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005884-&&-actin filament-%%-GO:0030017-&&-sarcomere-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0016020-&&-membrane-%%-GO:0030016-&&-myofibril|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0005523-&&-tropomyosin binding	G:9606:TMOD1				TMOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMOD1	0.38800587	0.20647773	39	4	FALSE	TMOD1	TMOD1	150.0769231	0	39	0	0.7371199	FALSE	0	TMOD1	94118	0.05570325
788784	taxon:9606	2.43248779	1.13E-04	176908	1902	mitogen-activated protein kinase-activated protein kinase 3	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0034097-&&-response to cytokine-%%-GO:0044351-&&-macropinocytosis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007165-&&-signal transduction-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MAPKAPK3			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway-%%-hsa04370-&&-VEGF signaling pathway	MAPKAPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPKAPK3	0.41110176	0.07962213	39	5	FALSE	MAPKAPK3	MAPKAPK3	187.8461539	0	39	0	0.76125204	FALSE	0	MAPKAPK3	186632	0.05200694
788803	taxon:9606	2.60879156	6.06E-05	176840	1902	twist family bHLH transcription factor 1	gene	biological_process-&-1&-GO:0001764-&&-neuron migration-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0061029-&&-eyelid development in camera-type eye-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071639-&&-positive regulation of monocyte chemotactic protein-1 production-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0001503-&&-ossification-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0003180-&&-aortic valve morphogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:2000793-&&-cell proliferation involved in heart valve development-%%-GO:0035067-&&-negative regulation of histone acetylation-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0060900-&&-embryonic camera-type eye formation-%%-GO:2000276-&&-negative regulation of oxidative phosphorylation uncoupler activity-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0048511-&&-rhythmic process-%%-GO:0042476-&&-odontogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:2000802-&&-positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0035359-&&-negative regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060021-&&-palate development-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0060363-&&-cranial suture morphogenesis-%%-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0003253-&&-cardiac neural crest cell migration involved in outflow tract morphogenesis-%%-GO:0033128-&&-negative regulation of histone phosphorylation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:2000780-&&-negative regulation of double-strand break repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:TWIST1			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	TWIST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TWIST1	0.38331924	0.17717718	39	4	FALSE	TWIST1	TWIST1	148.0540541	0	38	0	0.73186807	FALSE	1	TWIST1	75832	0.05900919
788847	taxon:9606	2.6187175	6.05E-05	176757	1902	ubiquitin specific peptidase 1	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0001501-&&-skeletal system development-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP1			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	USP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP1	0.38186631	0.06606607	39	4	FALSE	USP1	USP1	117.7297297	0	38	0	0.73021375	FALSE	1	USP1	83064	0.04825145
789054	taxon:9606	2.57538995	1.34E-04	176278	1902	TNF receptor superfamily member 10b	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006915-&&-apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0045569-&&-TRAIL binding-%%-GO:0005515-&&-protein binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:TNFRSF10B	TNFRSF10B	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF10B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF10B	0.38829071	0.21187584	39	4	FALSE	TNFRSF10B	TNFRSF10B	124.5384615	0	39	0	0.73743501	FALSE	0	TNFRSF10B	141888	0.0460401
789210	taxon:9606	2.54892075	3.22E-05	175992	1902	apoptosis inhibitor 5	gene	biological_process-&-1&-GO:2000270-&&-negative regulation of fibroblast apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding	G:9606:API5				API5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-API5	0.39232291	0.13663664	39	4	FALSE	API5	API5	180.1621622	0	38	0	0.74184654	FALSE	1	API5	63960	0.06236143
789278	taxon:9606	2.55601071	6.75E-05	175839	1902	URI1, prefoldin like chaperone	gene	biological_process-&-1&-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0009615-&&-response to virus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071383-&&-cellular response to steroid hormone stimulus|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0019212-&&-phosphatase inhibitor activity	G:9606:URI1				URI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-URI1	0.39123467	0.18318318	39	4	FALSE	URI1	URI1	146.4054054	0	38	0	0.74066488	FALSE	1	URI1	92314	0.05162219
789295	taxon:9606	2.68378762	5.34E-05	175807	1902	chromodomain Y-like	gene	biological_process-&-1&-GO:0016573-&&-histone acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0035064-&&-methylated histone binding	G:9606:CDYL				CDYL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDYL	0.37260773	0.29419703	39	4	FALSE	CDYL	CDYL	213.8461539	0	39	0	0.71936873	FALSE	0	CDYL	110504	0.10293446
789302	taxon:9606	2.42839137	1.20E-04	175788	1902	mitogen-activated protein kinase kinase kinase kinase 4	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030033-&&-microvillus assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0046328-&&-regulation of JNK cascade|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004111-&&-creatine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:MAP4K4			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP4K4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP4K4	0.41179524	0.09041835	39	4	FALSE	MAP4K4	MAP4K4	190.7692308	0	39	0	0.76193477	FALSE	0	MAP4K4	185560	0.05255421
789405	taxon:9606	2.50007878	4.38E-05	175544	1902	thyroid hormone receptor interactor 4	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0045661-&&-regulation of myoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901998-&&-toxin transport|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0099053-&&-activating signal cointegrator 1 complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0002020-&&-protease binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044389-&&-ubiquitin-like protein ligase binding	G:9606:TRIP4				TRIP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP4	0.3999874	0.28828829	39	4	FALSE	TRIP4	TRIP4	201.3513514	0	38	0	0.74998687	FALSE	1	TRIP4	93776	0.06267881
789531	taxon:9606	2.52103356	9.70E-05	175247	1902	polyglutamine binding protein 1	gene	biological_process-&-1&-GO:0043484-&&-regulation of RNA splicing-%%-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031175-&&-neuron projection development-%%-GO:0048814-&&-regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0071598-&&-neuronal ribonucleoprotein granule-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:PQBP1			KEGG-&-1&-hsa03040-&&-Spliceosome	PQBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PQBP1	0.39666271	0.0782726	39	4	FALSE	PQBP1	PQBP1	150.5897436	0	39	0	0.74649441	FALSE	0	PQBP1	129768	0.04948608
789568	taxon:9606	2.59067276	5.18E-05	175160	1902	centrosomal protein 350	gene	biological_process-&-1&-GO:0034453-&&-microtubule anchoring|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:CEP350				CEP350	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP350	0.38600012	0.17139001	39	4	FALSE	CEP350	CEP350	138.2820513	0	39	0	0.73488787	FALSE	0	CEP350	86384	0.05242014
789584	taxon:9606	2.47455491	4.27E-05	175128	1902	telomere maintenance 2	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:1904515-&&-positive regulation of TORC2 signaling-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:1904263-&&-positive regulation of TORC1 signaling|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0031931-&&-TORC1 complex-%%-GO:0031932-&&-TORC2 complex-%%-GO:0034399-&&-nuclear periphery-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0032947-&&-protein complex scaffold	G:9606:TELO2			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway-%%-hsa03460-&&-Fanconi anemia pathway	TELO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TELO2	0.40411308	0.17139001	39	4	FALSE	TELO2	TELO2	184.0769231	0	39	0	0.75424085	FALSE	0	TELO2	83122	0.05517893
789675	taxon:9606	2.77769025	6.89E-05	174917	1902	MAD2 mitotic arrest deficient-like 2 (yeast)	gene	biological_process-&-1&-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042772-&&-DNA damage response, signal transduction resulting in transcription-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006302-&&-double-strand break repair-%%-GO:0007015-&&-actin filament organization-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2000048-&&-negative regulation of cell-cell adhesion mediated by cadherin-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:1904667-&&-negative regulation of ubiquitin protein ligase activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016035-&&-zeta DNA polymerase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005680-&&-anaphase-promoting complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008432-&&-JUN kinase binding	G:9606:MAD2L2			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05131-&&-Shigellosis	MAD2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAD2L2	0.36001134	0.02552553	39	4	FALSE	MAD2L2	MAD2L2	65.91891892	0	38	0	0.70371829	FALSE	1	MAD2L2	68920	0.04363269
789706	taxon:9606	2.50449031	8.62E-05	174854	1902	autophagy related 7	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0000422-&&-mitophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:1902617-&&-response to fluoride-%%-GO:0051607-&&-defense response to virus-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006914-&&-autophagy-%%-GO:0006497-&&-protein lipidation-%%-GO:0007568-&&-aging-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031401-&&-positive regulation of protein modification process-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0071455-&&-cellular response to hyperoxia-%%-GO:0009749-&&-response to glucose-%%-GO:0039521-&&-suppression by virus of host autophagy-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090298-&&-negative regulation of mitochondrial DNA replication-%%-GO:0071315-&&-cellular response to morphine-%%-GO:0061025-&&-membrane fusion-%%-GO:0010508-&&-positive regulation of autophagy|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0030424-&&-axon-%%-GO:0005930-&&-axoneme-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004839-&&-ubiquitin activating enzyme activity-%%-GO:0019778-&&-Atg12 activating enzyme activity-%%-GO:0008134-&&-transcription factor binding	G:9606:ATG7			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04216-&&-Ferroptosis-%%-hsa04136-&&-Autophagy - other	ATG7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG7	0.39928284	0.15789474	39	4	FALSE	ATG7	ATG7	143.2564103	0	39	0	0.74925161	FALSE	0	ATG7	114808	0.04555504
789819	taxon:9606	2.52985663	3.23E-05	174569	1902	MALT1 paracaspase	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009620-&&-response to fungus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0006952-&&-defense response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006508-&&-proteolysis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0050856-&&-regulation of T cell receptor signaling pathway-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0001923-&&-B-1 B cell differentiation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0042098-&&-T cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0051168-&&-nuclear export-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0032449-&&-CBM complex-%%-GO:0043234-&&-protein complex-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0019209-&&-kinase activator activity-%%-GO:0002020-&&-protease binding-%%-GO:0043621-&&-protein self-association	G:9606:MALT1			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MALT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MALT1	0.39527932	0.21921922	39	4	FALSE	MALT1	MALT1	170.7567568	0	38	0	0.7450239	FALSE	1	MALT1	66372	0.05720494
789849	taxon:9606	2.53269261	7.10E-05	174515	1902	Sec61 translocon beta subunit	gene	biological_process-&-1&-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0031204-&&-posttranslational protein targeting to membrane, translocation-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006616-&&-SRP-dependent cotranslational protein targeting to membrane, translocation-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031205-&&-endoplasmic reticulum Sec complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005784-&&-Sec61 translocon complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0015450-&&-P-P-bond-hydrolysis-driven protein transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0048408-&&-epidermal growth factor binding-%%-GO:0003723-&&-RNA binding	G:9606:SEC61B			KEGG-&-1&-hsa03060-&&-Protein export-%%-hsa04145-&&-Phagosome-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC61B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC61B	0.3948367	0.11861862	39	4	FALSE	SEC61B	SEC61B	165.972973	0	38	0	0.74455123	FALSE	1	SEC61B	110906	0.05602563
790394	taxon:9606	2.68725382	1.75E-04	173125	1902	LDOC1, regulator of NFKB signaling	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001893-&&-maternal placenta development-%%-GO:0060137-&&-maternal process involved in parturition-%%-GO:1903547-&&-regulation of growth hormone activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:LDOC1				LDOC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDOC1	0.37212711	0.06456456	39	4	FALSE	LDOC1	LDOC1	91.16216216	0	38	0	0.71879103	FALSE	1	LDOC1	224682	0.04467814
790628	taxon:9606	2.42098629	6.74E-05	171715	1902	sorting nexin 9	gene	biological_process-&-1&-GO:0060988-&&-lipid tube assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0036089-&&-cleavage furrow formation-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0097320-&&-plasma membrane tubulation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0016197-&&-endosomal transport-%%-GO:0006897-&&-endocytosis-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0071933-&&-Arp2/3 complex binding-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding	G:9606:SNX9				SNX9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX9	0.4130548	0.10510511	39	4	FALSE	SNX9	SNX9	255.7027027	0	38	0	0.76316895	FALSE	1	SNX9	133674	0.06969391
790720	taxon:9606	2.67953364	7.65E-05	171392	1902	NADH:ubiquinone oxidoreductase subunit A13	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0045039-&&-protein import into mitochondrial inner membrane-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005746-&&-mitochondrial respiratory chain-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005747-&&-mitochondrial respiratory chain complex I|molecular_function-&-1&-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFA13			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA13	0.37319927	0.20917679	39	4	FALSE	NDUFA13	NDUFA13	96.46153846	0	39	0	0.72007773	FALSE	0	NDUFA13	93314	0.04643339
790790	taxon:9606	2.67023791	2.10E-05	171194	1902	anaphase promoting complex subunit 4	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:ANAPC4			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC4	0.37449847	0.30780781	39	4	FALSE	ANAPC4	ANAPC4	126.0540541	0	38	0	0.72162702	FALSE	1	ANAPC4	48802	0.05769064
790867	taxon:9606	2.59098787	6.36E-05	170834	1902	pleckstrin homology domain containing A5	gene	biological_process-&-1&-GO:0061458-&&-reproductive system development-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding	G:9606:PLEKHA5				PLEKHA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLEKHA5	0.38595318	0.07207207	39	4	FALSE	PLEKHA5	PLEKHA5	136.5405405	0	38	0	0.73483536	FALSE	1	PLEKHA5	89338	0.0520425
790905	taxon:9606	2.54277611	7.63E-05	170730	1902	periphilin 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0031424-&&-keratinization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:PPHLN1				PPHLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPHLN1	0.39327096	0.06606607	39	4	FALSE	PPHLN1	PPHLN1	144.5675676	0	38	0	0.74287065	FALSE	1	PPHLN1	110224	0.04947697
790927	taxon:9606	2.62297148	9.16E-05	170690	1902	ATPase H+ transporting V1 subunit H	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007035-&&-vacuolar acidification-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0033572-&&-transferrin transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0016032-&&-viral process-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0000221-&&-vacuolar proton-transporting V-type ATPase, V1 domain-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism-%%-GO:0030234-&&-enzyme regulator activity-%%-GO:0016887-&&-ATPase activity	G:9606:ATP6V1H			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04142-&&-Lysosome-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V1H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1H	0.381247	0.08367072	39	4	FALSE	ATP6V1H	ATP6V1H	106.1025641	0	39	0	0.72950475	FALSE	0	ATP6V1H	107232	0.04387866
790982	taxon:9606	2.57743816	5.91E-05	154134	1902	cyclin dependent kinase 11A	gene	biological_process-&-1&-GO:0001558-&&-regulation of cell growth-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050684-&&-regulation of mRNA processing-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK11A				CDK11A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK11A	0.38798215	0.08097166	39	4	FALSE	CDK11A	CDK11A	130.6923077	0	39	0	0.73709364	FALSE	0	CDK11A	88812	0.04854536
790985	taxon:9606	2.5125256	2.95E-05	170495	1902	HEAT repeat containing 1	gene	biological_process-&-1&-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0034455-&&-t-UTP complex-%%-GO:0032040-&&-small-subunit processome-%%-GO:0001650-&&-fibrillar center-%%-GO:0030686-&&-90S preribosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding	G:9606:HEATR1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	HEATR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEATR1	0.39800589	0.12010796	39	4	FALSE	HEATR1	HEATR1	273.8974359	0	39	0	0.7479124	FALSE	0	HEATR1	103518	0.08833288
791256	taxon:9606	2.4164172	3.95E-05	169491	1902	zinc finger CCCH-type containing, antiviral 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0009615-&&-response to virus-%%-GO:0051607-&&-defense response to virus-%%-GO:0039507-&&-suppression by virus of host molecular function-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0071360-&&-cellular response to exogenous dsRNA|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:ZC3HAV1				ZC3HAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZC3HAV1	0.41383582	0.12820513	39	4	FALSE	ZC3HAV1	ZC3HAV1	279.1538462	0	39	0	0.76393047	FALSE	0	ZC3HAV1	115566	0.07532441
791293	taxon:9606	2.51047739	4.28E-05	169311	1902	E1A binding protein p400	gene	biological_process-&-1&-GO:0043968-&&-histone H2A acetylation-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0000812-&&-Swr1 complex-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:1990405-&&-protein antigen binding-%%-GO:0005515-&&-protein binding	G:9606:EP400				EP400	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EP400	0.39833061	0.27125506	39	4	FALSE	EP400	EP400	214.8205128	0	39	0	0.74825377	FALSE	0	EP400	90994	0.06853697
791400	taxon:9606	2.53710414	1.29E-04	168785	1902	kelch like family member 12	gene	biological_process-&-1&-GO:0006513-&&-protein monoubiquitination-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KLHL12				KLHL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL12	0.39415016	0.08408408	39	4	FALSE	KLHL12	KLHL12	175.6216216	0	38	0	0.74381598	FALSE	1	KLHL12	166616	0.05970232
791426	taxon:9606	2.63006145	5.27E-05	168692	1902	mitochondrial ribosomal protein L9	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:MRPL9			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL9	0.38021925	0.17813765	39	4	FALSE	MRPL9	MRPL9	131.4615385	0	39	0	0.72832309	FALSE	0	MRPL9	76810	0.05498492
791816	taxon:9606	2.61225776	2.70E-05	166728	1902	glyoxylate reductase 1 homolog	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0004616-&&-phosphogluconate dehydrogenase (decarboxylating) activity-%%-GO:0035064-&&-methylated histone binding	G:9606:GLYR1				GLYR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLYR1	0.38281062	0.31443995	39	4	FALSE	GLYR1	GLYR1	258.7435897	0	39	0	0.73129037	FALSE	0	GLYR1	64042	0.10350807
791839	taxon:9606	2.64849535	8.60E-06	166605	1902	poly(ADP-ribose) polymerase family member 10	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010847-&&-regulation of chromatin assembly-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:1900045-&&-negative regulation of protein K63-linked ubiquitination-%%-GO:0070213-&&-protein auto-ADP-ribosylation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0033159-&&-negative regulation of protein import into nucleus, translocation-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0070212-&&-protein poly-ADP-ribosylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:PARP10				PARP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP10	0.37757287	0.43184885	39	4	FALSE	PARP10	PARP10	269.2051282	0	39	0	0.72525077	FALSE	0	PARP10	38182	0.11806118
791980	taxon:9606	2.61430597	6.49E-05	182779	1902	acylaminoacyl-peptide hydrolase	gene	biological_process-&-1&-GO:0006415-&&-translational termination-%%-GO:0050435-&&-beta-amyloid metabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008242-&&-omega peptidase activity-%%-GO:0042802-&&-identical protein binding	G:9606:APEH				APEH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APEH	0.3825107	0.14864865	39	4	FALSE	APEH	APEH	119.9189189	0	38	0	0.730949	FALSE	1	APEH	85444	0.0484649
792175	taxon:9606	2.47313692	7.36E-05	182473	1902	ADP ribosylation factor 4	gene	biological_process-&-1&-GO:0007612-&&-learning-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0016477-&&-cell migration-%%-GO:0061512-&&-protein localization to cilium-%%-GO:0015031-&&-protein transport-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0007420-&&-brain development-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0045176-&&-apical protein localization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060996-&&-dendritic spine development-%%-GO:0048678-&&-response to axon injury-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0043197-&&-dendritic spine|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:ARF4				ARF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF4	0.40434478	0.1511471	39	4	FALSE	ARF4	ARF4	202.5641026	0	39	0	0.75447718	FALSE	0	ARF4	141368	0.06074454
792181	taxon:9606	2.49046794	9.85E-05	166087	1902	tripartite motif containing 41	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM41				TRIM41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM41	0.40153097	0.08258258	39	4	FALSE	TRIM41	TRIM41	156.0540541	0	38	0	0.75158868	FALSE	1	TRIM41	146318	0.04833374
792316	taxon:9606	2.74192532	5.33E-05	182243	1902	centrin 2	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0051301-&&-cell division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0000715-&&-nucleotide-excision repair, DNA damage recognition-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0007099-&&-centriole replication-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005813-&&-centrosome-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005622-&&-intracellular-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0071942-&&-XPC complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0032795-&&-heterotrimeric G-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding	G:9606:CETN2			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	CETN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CETN2	0.36470723	0.07017544	39	4	FALSE	CETN2	CETN2	97.8974359	0	39	0	0.70967911	FALSE	0	CETN2	67950	0.0570067
792331	taxon:9606	2.5588467	1.92E-05	182213	1902	chromodomain helicase DNA binding protein 1	gene	biological_process-&-1&-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:CHD1				CHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD1	0.39080106	0.28228228	39	4	FALSE	CHD1	CHD1	290.4594595	0	38	0	0.74019222	FALSE	1	CHD1	77992	0.10291723
792736	taxon:9606	2.58862455	1.13E-04	181474	1902	dystrophia myotonica, WD repeat containing	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:DMWD				DMWD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMWD	0.38630554	0.05128205	39	4	FALSE	DMWD	DMWD	109.6923077	0	39	0	0.73522924	FALSE	0	DMWD	117858	0.04147842
792741	taxon:9606	2.52796597	6.37E-05	181462	1902	dynein cytoplasmic 1 intermediate chain 1	gene	biological_process-&-1&-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0047496-&&-vesicle transport along microtubule|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005874-&&-microtubule-%%-GO:0031982-&&-vesicle-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0055037-&&-recycling endosome-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0045503-&&-dynein light chain binding-%%-GO:0030507-&&-spectrin binding	G:9606:DYNC1I1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome	DYNC1I1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC1I1	0.39557495	0.1120108	39	4	FALSE	DYNC1I1	DYNC1I1	159.948718	0	39	0	0.74533901	FALSE	0	DYNC1I1	103672	0.05322882
792788	taxon:9606	2.52985663	5.75E-05	181361	1902	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0006475-&&-internal protein amino acid acetylation|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0016508-&&-long-chain-enoyl-CoA hydratase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0004165-&&-dodecenoyl-CoA delta-isomerase activity-%%-GO:0004300-&&-enoyl-CoA hydratase activity-%%-GO:0005102-&&-receptor binding	G:9606:EHHADH			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00071-&&-Fatty acid degradation	EHHADH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHHADH	0.39527932	0.08906883	39	4	FALSE	EHHADH	EHHADH	160.7948718	0	39	0	0.7450239	FALSE	0	EHHADH	104542	0.05366288
793115	taxon:9606	2.77343627	7.44E-05	180707	1902	growth differentiation factor 9	gene	biological_process-&-1&-GO:0030509-&&-BMP signaling pathway-%%-GO:0001555-&&-oocyte growth-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0007292-&&-female gamete generation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0048468-&&-cell development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:2000870-&&-regulation of progesterone secretion-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity	G:9606:GDF9	GDF9	TRUE	KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	GDF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GDF9	0.36056354	0.0391363	39	4	FALSE	GDF9	GDF9	70.1025641	0	39	0	0.70442729	FALSE	0	GDF9	85176	0.04679358
793245	taxon:9606	2.65148889	7.62E-05	180453	1902	inhibitor of DNA binding 1, HLH protein	gene	biological_process-&-1&-GO:1901653-&&-cellular response to peptide-%%-GO:0007507-&&-heart development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030182-&&-neuron differentiation-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001525-&&-angiogenesis-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0043534-&&-blood vessel endothelial cell migration-%%-GO:0007623-&&-circadian rhythm-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045602-&&-negative regulation of endothelial cell differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0090074-&&-negative regulation of protein homodimerization activity-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0046677-&&-response to antibiotic-%%-GO:1903351-&&-cellular response to dopamine-%%-GO:0060426-&&-lung vasculature development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0010621-&&-negative regulation of transcription by transcription factor localization-%%-GO:0007420-&&-brain development-%%-GO:0031648-&&-protein destabilization-%%-GO:0032963-&&-collagen metabolic process-%%-GO:0036164-&&-cell-abiotic substrate adhesion-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0060425-&&-lung morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0070628-&&-proteasome binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:ID1			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	ID1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ID1	0.37714659	0.03778677	39	4	FALSE	ID1	ID1	91.71794872	0	39	0	0.72475185	FALSE	0	ID1	94164	0.04102564
793352	taxon:9606	2.65243422	7.84E-05	180249	1902	forkhead box A3	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0030154-&&-cell differentiation-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXA3			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young	FOXA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXA3	0.37701218	0.05668016	39	4	FALSE	FOXA3	FOXA3	103.8717949	0	39	0	0.7245943	FALSE	0	FOXA3	95980	0.0463811
793365	taxon:9606	2.52796597	1.58E-04	180232	1902	integrin subunit alpha 5	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0001525-&&-angiogenesis-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0007613-&&-memory-%%-GO:0033631-&&-cell-cell adhesion mediated by integrin-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:1903672-&&-positive regulation of sprouting angiogenesis-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:0031589-&&-cell-substrate adhesion|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0071062-&&-alphav-beta3 integrin-vitronectin complex-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0001726-&&-ruffle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005911-&&-cell-cell junction-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0005178-&&-integrin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding	G:9606:ITGA5			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04145-&&-Phagosome-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05131-&&-Shigellosis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05133-&&-Pertussis	ITGA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA5	0.39557495	0.09311741	39	4	FALSE	ITGA5	ITGA5	145.3846154	0	39	0	0.74533901	FALSE	0	ITGA5	184608	0.04866299
787361	taxon:9606	2.42539783	1.00E-04	179568	1902	mucin 1, cell surface associated	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing-%%-GO:0090240-&&-positive regulation of histone H4 acetylation-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0043618-&&-regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0031982-&&-vesicle-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0002039-&&-p53 binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:MUC1	MUC1	TRUE		MUC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MUC1	0.41230349	0.19630156	38	4	FALSE	MUC1	MUC1	218.9736842	0	38	0	0.7624337	FALSE	0	MUC1	139246	0.06016174
787514	taxon:9606	2.63951473	6.99E-05	179305	1902	membrane palmitoylated protein 1	gene	biological_process-&-1&-GO:0090022-&&-regulation of neutrophil chemotaxis-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0046710-&&-GDP metabolic process|cellular_component-&-1&-GO:0032420-&&-stereocilium-%%-GO:0030863-&&-cortical cytoskeleton-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004385-&&-guanylate kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MPP1				MPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPP1	0.37885752	0.03271693	38	4	FALSE	MPP1	MPP1	105.3421053	0	38	0	0.72674754	FALSE	0	MPP1	90240	0.04566597
787535	taxon:9606	2.62092327	4.72E-05	179229	1902	protein phosphatase 1 regulatory inhibitor subunit 2	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity|cellular_component-&-1&-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004865-&&-protein serine/threonine phosphatase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:PPP1R2				PPP1R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R2	0.38154494	0.10384068	38	4	FALSE	PPP1R2	PPP1R2	131.5789474	0	38	0	0.72984612	FALSE	0	PPP1R2	77172	0.05374957
787564	taxon:9606	2.79187017	4.57E-05	179165	1902	NADH:ubiquinone oxidoreductase subunit B9	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding	G:9606:NDUFB9			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFB9	0.35818284	0.15931721	38	5	FALSE	NDUFB9	NDUFB9	74.26315789	0	38	0	0.70135497	FALSE	0	NDUFB9	52724	0.05165828
787572	taxon:9606	2.72443674	5.16E-05	179153	1902	NADH:ubiquinone oxidoreductase core subunit V2	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0048738-&&-cardiac muscle tissue development-%%-GO:0007399-&&-nervous system development-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0045272-&&-plasma membrane respiratory chain complex I|molecular_function-&-1&-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0009055-&&-electron carrier activity	G:9606:NDUFV2			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFV2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFV2	0.36704835	0.24751067	38	4	FALSE	NDUFV2	NDUFV2	88.84210526	0	38	0	0.71259388	FALSE	0	NDUFV2	70498	0.04893024
787628	taxon:9606	2.696392	1.11E-04	179061	1902	notch 2	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0002315-&&-marginal zone B cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001709-&&-cell fate determination-%%-GO:0046849-&&-bone remodeling-%%-GO:0007399-&&-nervous system development-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:0016049-&&-cell growth-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0050793-&&-regulation of developmental process-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0043235-&&-receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0038049-&&-transcription factor activity, ligand-activated RNA polymerase II transcription factor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:NOTCH2	NOTCH2	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	NOTCH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH2	0.37086596	0.03129445	38	4	FALSE	NOTCH2	NOTCH2	76.94736842	0	38	0	0.717268	FALSE	0	NOTCH2	104058	0.03970596
787774	taxon:9606	2.53048684	7.47E-05	178801	1902	protein phosphatase 2 regulatory subunit B'epsilon	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000159-&&-protein phosphatase type 2A complex|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2R5E			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R5E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R5E	0.39518087	0.18571429	38	4	FALSE	PPP2R5E	PPP2R5E	145.1666667	0	37	0	0.74491886	FALSE	1	PPP2R5E	97852	0.04849734
787810	taxon:9606	2.75500236	4.45E-05	178759	1902	protein kinase cAMP-dependent type II regulatory subunit beta	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0007612-&&-learning-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0097332-&&-response to antipsychotic drug-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0097338-&&-response to clozapine-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043198-&&-dendritic shaft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043197-&&-dendritic spine-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0097546-&&-ciliary base-%%-GO:0005813-&&-centrosome-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PRKAR2B	PRKAR2B	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	PRKAR2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAR2B	0.3629761	0.09047619	38	4	FALSE	PRKAR2B	PRKAR2B	69.66666667	0	37	0	0.70749961	FALSE	1	PRKAR2B	49730	0.04287477
787817	taxon:9606	2.63825429	5.17E-05	178748	1902	protein kinase C theta	gene	biological_process-&-1&-GO:0001558-&&-regulation of cell growth-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:2000570-&&-positive regulation of T-helper 2 cell activation-%%-GO:0070233-&&-negative regulation of T cell apoptotic process-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0007411-&&-axon guidance-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:2000318-&&-positive regulation of T-helper 17 type immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0060326-&&-cell chemotaxis|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKCQ			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04660-&&-T cell receptor signaling pathway	PRKCQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCQ	0.37903852	0.16190476	38	4	FALSE	PRKCQ	PRKCQ	130.3333333	0	37	0	0.72695762	FALSE	1	PRKCQ	70384	0.05642173
787852	taxon:9606	2.65274933	6.79E-05	178716	1902	prion protein	gene	biological_process-&-1&-GO:1901216-&&-positive regulation of neuron death-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0008152-&&-metabolic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0070885-&&-negative regulation of calcineurin-NFAT signaling cascade-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:1904645-&&-response to beta-amyloid-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0007616-&&-long-term memory-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:1900272-&&-negative regulation of long-term synaptic potentiation-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:1902951-&&-negative regulation of dendritic spine maintenance-%%-GO:1905664-&&-regulation of calcium ion import across plasma membrane-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005737-&&-cytoplasm-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0043008-&&-ATP-dependent protein binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0005521-&&-lamin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0008017-&&-microtubule binding	G:9606:PRNP			KEGG-&-1&-hsa05020-&&-Prion diseases-%%-hsa04216-&&-Ferroptosis	PRNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRNP	0.37696739	0.06349206	38	5	FALSE	PRNP	PRNP	98.30555556	0	37	0	0.72454178	FALSE	1	PRNP	73812	0.04441178
788067	taxon:9606	2.74460375	2.95E-05	178290	1902	mitochondrial ribosomal protein L23	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0001650-&&-fibrillar center-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MRPL23			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL23	0.36435132	0.21337127	38	4	FALSE	MRPL23	MRPL23	121.0789474	0	38	0	0.70923271	FALSE	0	MRPL23	43452	0.0713023
788221	taxon:9606	2.4063337	2.78E-05	178053	1902	replication factor C subunit 3	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0046683-&&-response to organophosphorus-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage|cellular_component-&-1&-GO:0005663-&&-DNA replication factor C complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031390-&&-Ctf18 RFC-like complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity	G:9606:RFC3			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	RFC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFC3	0.41556996	0.29871977	38	4	FALSE	RFC3	RFC3	296.1842105	0	38	0	0.76561105	FALSE	0	RFC3	86934	0.07861903
788301	taxon:9606	2.48715929	2.67E-05	177931	1902	ribonucleotide reductase catalytic subunit M1	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0009263-&&-deoxyribonucleotide biosynthetic process-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006206-&&-pyrimidine nucleobase metabolic process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0021846-&&-cell proliferation in forebrain-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0008584-&&-male gonad development-%%-GO:0060041-&&-retina development in camera-type eye|cellular_component-&-1&-GO:0042995-&&-cell projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004748-&&-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor-%%-GO:0005515-&&-protein binding	G:9606:RRM1			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	RRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRM1	0.40206512	0.13174603	38	4	FALSE	RRM1	RRM1	233.9166667	0	37	0	0.75214012	FALSE	1	RRM1	66734	0.07144675
788618	taxon:9606	2.64124783	4.59E-05	177298	1902	tec protein tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0010543-&&-regulation of platelet activation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042246-&&-tissue regeneration-%%-GO:0030154-&&-cell differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:TEC			KEGG-&-1&-hsa04380-&&-Osteoclast differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	TEC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEC	0.37860892	0.26190476	38	4	FALSE	TEC	TEC	125.7222222	0	37	0	0.72645869	FALSE	1	TEC	67458	0.05480448
788905	taxon:9606	2.49062549	7.70E-05	176643	1902	ZFP36 ring finger protein	gene	biological_process-&-1&-GO:0032680-&&-regulation of tumor necrosis factor production-%%-GO:0000165-&&-MAPK cascade-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051028-&&-mRNA transport-%%-GO:0009611-&&-response to wounding-%%-GO:0045616-&&-regulation of keratinocyte differentiation-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:1904246-&&-negative regulation of polynucleotide adenylyltransferase activity-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:1904582-&&-positive regulation of intracellular mRNA localization-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0045085-&&-negative regulation of interleukin-2 biosynthetic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0070935-&&-3'-UTR-mediated mRNA stabilization-%%-GO:1901835-&&-positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0035278-&&-miRNA mediated inhibition of translation-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0031086-&&-nuclear-transcribed mRNA catabolic process, deadenylation-independent decay-%%-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0042594-&&-response to starvation-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:1902172-&&-regulation of keratinocyte apoptotic process|cellular_component-&-1&-GO:0010494-&&-cytoplasmic stress granule-%%-GO:1990904-&&-ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0098745-&&-Dcp1-Dcp2 complex-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0070578-&&-RISC-loading complex-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0030014-&&-CCR4-NOT complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017091-&&-AU-rich element binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0019957-&&-C-C chemokine binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:ZFP36			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	ZFP36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFP36	0.40150557	0.12233286	38	4	FALSE	ZFP36	ZFP36	187.2631579	0	38	0	0.75156242	FALSE	0	ZFP36	106112	0.05791591
788917	taxon:9606	2.57633528	5.39E-05	176603	1902	speckle type BTB/POZ protein	gene	biological_process-&-1&-GO:0030162-&&-regulation of proteolysis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:2000676-&&-positive regulation of type B pancreatic cell apoptotic process|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding	G:9606:SPOP			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway	SPOP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPOP	0.38814824	0.0968254	38	4	FALSE	SPOP	SPOP	152.8055556	0	37	0	0.73727745	FALSE	1	SPOP	86132	0.05635536
788918	taxon:9606	2.5522294	6.60E-05	176597	1902	early endosome antigen 1	gene	biological_process-&-1&-GO:0016189-&&-synaptic vesicle to endosome fusion-%%-GO:0006906-&&-vesicle fusion-%%-GO:0006897-&&-endocytosis-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0045022-&&-early endosome to late endosome transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0098793-&&-presynapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0044308-&&-axonal spine-%%-GO:0005969-&&-serine-pyruvate aminotransferase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:EEA1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis	EEA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEA1	0.39181431	0.08412698	38	4	FALSE	EEA1	EEA1	154.5555556	0	37	0	0.7412951	FALSE	1	EEA1	102608	0.05425744
789077	taxon:9606	2.4328029	6.03E-05	176242	1902	guanine monophosphate synthase	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006177-&&-GMP biosynthetic process-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0009113-&&-purine nucleobase biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003921-&&-GMP synthase activity-%%-GO:0016462-&&-pyrophosphatase activity-%%-GO:0003922-&&-GMP synthase (glutamine-hydrolyzing) activity	G:9606:GMPS			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	GMPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMPS	0.41104851	0.14651494	38	4	FALSE	GMPS	GMPS	266.1842105	0	38	0	0.76119952	FALSE	0	GMPS	127040	0.07400767
789103	taxon:9606	2.57586261	3.20E-05	176194	1902	eukaryotic translation initiation factor 2B subunit gamma	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0051716-&&-cellular response to stimulus-%%-GO:0021766-&&-hippocampus development-%%-GO:0009749-&&-response to glucose-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006413-&&-translational initiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043434-&&-response to peptide hormone|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0016779-&&-nucleotidyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding	G:9606:EIF2B3			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2B3	0.38821946	0.3047619	38	4	FALSE	EIF2B3	EIF2B3	151.6944444	0	37	0	0.73735623	FALSE	1	EIF2B3	58544	0.05573931
789123	taxon:9606	2.46778005	6.48E-05	176152	1902	adaptor related protein complex 3 delta 1 subunit	gene	biological_process-&-1&-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0098943-&&-neurotransmitter receptor transport, postsynaptic endosome to lysosome-%%-GO:0051138-&&-positive regulation of NK T cell differentiation-%%-GO:0006726-&&-eye pigment biosynthetic process-%%-GO:0032438-&&-melanosome organization-%%-GO:0035646-&&-endosome to melanosome transport-%%-GO:0016182-&&-synaptic vesicle budding from endosome-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048007-&&-antigen processing and presentation, exogenous lipid antigen via MHC class Ib-%%-GO:0048499-&&-synaptic vesicle membrane organization-%%-GO:0061088-&&-regulation of sequestering of zinc ion-%%-GO:0072657-&&-protein localization to membrane|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043195-&&-terminal bouton-%%-GO:0016020-&&-membrane-%%-GO:0030123-&&-AP-3 adaptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0098830-&&-presynaptic endosome-%%-GO:1904115-&&-axon cytoplasm|molecular_function-&-1&-GO:0005215-&&-transporter activity	G:9606:AP3D1			KEGG-&-1&-hsa04142-&&-Lysosome	AP3D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP3D1	0.4052225	0.15504979	38	4	FALSE	AP3D1	AP3D1	199.5263158	0	38	0	0.75536999	FALSE	0	AP3D1	109308	0.05898098
789221	taxon:9606	2.6633055	4.67E-05	175969	1902	THO complex 5	gene	biological_process-&-1&-GO:0006405-&&-RNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:2000002-&&-negative regulation of DNA damage checkpoint-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0046784-&&-viral mRNA export from host cell nucleus-%%-GO:0060215-&&-primitive hemopoiesis-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0031124-&&-mRNA 3'-end processing|cellular_component-&-1&-GO:0000445-&&-THO complex part of transcription export complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000346-&&-transcription export complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0000347-&&-THO complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:THOC5			KEGG-&-1&-hsa03013-&&-RNA transport	THOC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THOC5	0.37547326	0.11522048	38	5	FALSE	THOC5	THOC5	109.2368421	0	38	0	0.72278242	FALSE	0	THOC5	64024	0.04975967
789466	taxon:9606	2.5107925	3.57E-05	175400	1902	brain and reproductive organ-expressed (TNFRSF1A modulator)	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006915-&&-apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0051301-&&-cell division-%%-GO:0007165-&&-signal transduction-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006302-&&-double-strand break repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0031572-&&-G2 DNA damage checkpoint|cellular_component-&-1&-GO:0000152-&&-nuclear ubiquitin ligase complex-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070552-&&-BRISC complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000268-&&-peroxisome targeting sequence binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:BRE			KEGG-&-1&-hsa03440-&&-Homologous recombination	BRE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRE	0.39828062	0.16785206	38	4	FALSE	BRE	BRE	185.3157895	0	38	0	0.74820125	FALSE	0	BRE	75862	0.05952119
789543	taxon:9606	2.46305341	4.60E-05	175225	1902	Rho GTPase activating protein 32	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:ARHGAP32				ARHGAP32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP32	0.40600013	0.20056899	38	4	FALSE	ARHGAP32	ARHGAP32	208.2894737	0	38	0	0.75615776	FALSE	0	ARHGAP32	97490	0.06117416
789768	taxon:9606	2.54923586	3.10E-05	174734	1902	transducer of ERBB2, 1	gene	biological_process-&-1&-GO:0030509-&&-BMP signaling pathway-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0060212-&&-negative regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0017148-&&-negative regulation of translation-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|cellular_component-&-1&-GO:0030014-&&-CCR4-NOT complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0005515-&&-protein binding	G:9606:TOB1			KEGG-&-1&-hsa03018-&&-RNA degradation	TOB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOB1	0.39227441	0.14082504	38	4	FALSE	TOB1	TOB1	161.631579	0	38	0	0.74179402	FALSE	0	TOB1	64198	0.05643694
789891	taxon:9606	2.63037656	2.42E-05	174418	1902	ubiquitin specific peptidase 16	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0016578-&&-histone deubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0070537-&&-histone H2A K63-linked deubiquitination-%%-GO:0045901-&&-positive regulation of translational elongation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0035522-&&-monoubiquitinated histone H2A deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042393-&&-histone binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:USP16				USP16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP16	0.3801737	0.14126984	38	4	FALSE	USP16	USP16	192.7222222	0	37	0	0.72827057	FALSE	1	USP16	57288	0.08042096
789892	taxon:9606	2.53710414	6.80E-05	174413	1902	transducin beta like 3	gene	biological_process-&-1&-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus-%%-GO:0034388-&&-Pwp2p-containing subcomplex of 90S preribosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0030515-&&-snoRNA binding-%%-GO:0005515-&&-protein binding	G:9606:TBL3			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	TBL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL3	0.39415016	0.24751067	38	4	FALSE	TBL3	TBL3	198.0263158	0	38	0	0.74381598	FALSE	0	TBL3	106290	0.06668499
789971	taxon:9606	2.5821648	4.24E-05	174212	1902	exosome component 8	gene	biological_process-&-1&-GO:0043488-&&-regulation of mRNA stability-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0008150-&&-biological_process-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:EXOSC8			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC8	0.38727195	0.15873016	38	4	FALSE	EXOSC8	EXOSC8	152.5277778	0	37	0	0.73630587	FALSE	1	EXOSC8	76808	0.05657634
790073	taxon:9606	2.51882779	4.72E-05	173943	1902	mitogen-activated protein kinase kinase kinase kinase 1	gene	biological_process-&-1&-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0006950-&&-response to stress-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008349-&&-MAP kinase kinase kinase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity	G:9606:MAP4K1			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP4K1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP4K1	0.39701007	0.23174603	38	4	FALSE	MAP4K1	MAP4K1	192.9444444	0	37	0	0.74686203	FALSE	1	MAP4K1	90260	0.06314785
790388	taxon:9606	2.68772648	4.26E-05	173147	1902	zinc finger MYND-type containing 8	gene	biological_process-&-1&-GO:1902897-&&-regulation of postsynaptic density protein 95 clustering-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:1902952-&&-positive regulation of dendritic spine maintenance-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1903758-&&-negative regulation of transcription from RNA polymerase II promoter by histone modification-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0098815-&&-modulation of excitatory postsynaptic potential|cellular_component-&-1&-GO:0043197-&&-dendritic spine-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0070577-&&-lysine-acetylated histone binding	G:9606:ZMYND8				ZMYND8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMYND8	0.37206167	0.10526316	38	5	FALSE	ZMYND8	ZMYND8	104.1052632	0	38	0	0.71871225	FALSE	0	ZMYND8	62974	0.05138093
790667	taxon:9606	2.55774382	7.05E-05	171540	1902	drebrin like	gene	biological_process-&-1&-GO:0007416-&&-synapse assembly-%%-GO:0097178-&&-ruffle assembly-%%-GO:0002250-&&-adaptive immune response-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0071800-&&-podosome assembly-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005938-&&-cell cortex-%%-GO:0005576-&&-extracellular region-%%-GO:0002102-&&-podosome-%%-GO:0005769-&&-early endosome-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0030027-&&-lamellipodium-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0045296-&&-cadherin binding	G:9606:DBNL				DBNL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBNL	0.39096957	0.11428571	38	4	FALSE	DBNL	DBNL	141.9444444	0	37	0	0.74037603	FALSE	1	DBNL	101236	0.05018872
790762	taxon:9606	2.48700173	3.39E-05	171298	1902	HECT and RLD domain containing E3 ubiquitin protein ligase 5	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0050688-&&-regulation of defense response to virus-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0032020-&&-ISG15-protein conjugation-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0042296-&&-ISG15 transferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:HERC5				HERC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC5	0.40209059	0.1031746	38	4	FALSE	HERC5	HERC5	205.6388889	0	37	0	0.75216638	FALSE	1	HERC5	78604	0.06266307
790798	taxon:9606	2.42287695	1.29E-04	171175	1902	phosphoserine aminotransferase 1	gene	biological_process-&-1&-GO:0006564-&&-L-serine biosynthetic process-%%-GO:0008615-&&-pyridoxine biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004648-&&-O-phospho-L-serine:2-oxoglutarate aminotransferase activity	G:9606:PSAT1			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00750-&&-Vitamin B6 metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	PSAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSAT1	0.41273247	0.09815078	38	4	FALSE	PSAT1	PSAT1	183.3684211	0	38	0	0.76285384	FALSE	0	PSAT1	168794	0.05017573
790926	taxon:9606	2.57475973	6.43E-05	170691	1902	tRNA methyltransferase 6	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0030488-&&-tRNA methylation|cellular_component-&-1&-GO:0031515-&&-tRNA (m1A) methyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:TRMT6				TRMT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT6	0.38838575	0.08534851	38	4	FALSE	TRMT6	TRMT6	164.5526316	0	38	0	0.73754005	FALSE	0	TRMT6	101030	0.06043924
790933	taxon:9606	2.70348196	4.93E-05	170669	1902	family with sequence similarity 96 member B	gene	biological_process-&-1&-GO:0007059-&&-chromosome segregation-%%-GO:0016226-&&-iron-sulfur cluster assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071817-&&-MMXD complex-%%-GO:0097361-&&-CIA complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM96B				FAM96B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM96B	0.36989335	0.07965861	38	4	FALSE	FAM96B	FAM96B	84.81578947	0	38	0	0.71608634	FALSE	0	FAM96B	64326	0.0436067
790934	taxon:9606	2.4693556	2.32E-05	170668	1902	mitochondrial ribosomal protein S23	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005739-&&-mitochondrion-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS23				MRPS23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS23	0.40496395	0.30156472	38	4	FALSE	MRPS23	MRPS23	269.0263158	0	38	0	0.7551074	FALSE	0	MRPS23	73300	0.07975096
790950	taxon:9606	2.50512053	4.26E-05	170624	1902	WW domain binding protein 11	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0006364-&&-rRNA processing-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0050699-&&-WW domain binding	G:9606:WBP11			KEGG-&-1&-hsa03040-&&-Spliceosome	WBP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WBP11	0.39918239	0.14366999	38	4	FALSE	WBP11	WBP11	195.3947368	0	38	0	0.74914658	FALSE	0	WBP11	102754	0.06197402
791133	taxon:9606	2.81613361	2.28E-05	169936	1902	NADH:ubiquinone oxidoreductase subunit A12	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0006979-&&-response to oxidative stress|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFA12			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA12	0.35509679	0.3826458	38	4	FALSE	NDUFA12	NDUFA12	74.55263158	0	38	0	0.69731107	FALSE	0	NDUFA12	35582	0.05856918
791185	taxon:9606	2.48841973	3.66E-05	169792	1902	nucleoporin 133	gene	biological_process-&-1&-GO:0006999-&&-nuclear pore organization-%%-GO:0000972-&&-transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0022008-&&-neurogenesis-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0006325-&&-chromatin organization-%%-GO:0031081-&&-nuclear pore distribution-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0019083-&&-viral transcription-%%-GO:0021915-&&-neural tube development-%%-GO:0061053-&&-somite development-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0031080-&&-nuclear pore outer ring-%%-GO:0000940-&&-condensed chromosome outer kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005487-&&-nucleocytoplasmic transporter activity	G:9606:NUP133	NUP133	TRUE	KEGG-&-1&-hsa03013-&&-RNA transport	NUP133	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP133	0.40186147	0.16073969	38	4	FALSE	NUP133	NUP133	227.7368421	0	38	0	0.75193005	FALSE	0	NUP133	90120	0.06984178
791192	taxon:9606	2.54639987	7.10E-05	169781	1902	REST corepressor 3	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RCOR3				RCOR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCOR3	0.3927113	0.10953058	38	4	FALSE	RCOR3	RCOR3	142.1052632	0	38	0	0.74226669	FALSE	0	RCOR3	117286	0.04911917
791316	taxon:9606	2.70174886	2.88E-05	169200	1902	cytokine induced apoptosis inhibitor 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016226-&&-iron-sulfur cluster assembly-%%-GO:0032259-&&-methylation-%%-GO:0030097-&&-hemopoiesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0005515-&&-protein binding	G:9606:CIAPIN1				CIAPIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIAPIN1	0.37013063	0.16984127	38	4	FALSE	CIAPIN1	CIAPIN1	96.58333333	0	37	0	0.71637519	FALSE	1	CIAPIN1	42944	0.05023425
791573	taxon:9606	2.54860564	1.26E-04	167958	1902	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0050821-&&-protein stabilization-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006474-&&-N-terminal protein amino acid acetylation-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0017196-&&-N-terminal peptidyl-methionine acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031415-&&-NatA complex-%%-GO:0016020-&&-membrane-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004596-&&-peptide alpha-N-acetyltransferase activity-%%-GO:0003723-&&-RNA binding	G:9606:NAA15				NAA15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAA15	0.39237141	0.13086771	38	4	FALSE	NAA15	NAA15	196.3421053	0	38	0	0.74189906	FALSE	0	NAA15	146900	0.06830927
791648	taxon:9606	2.62911612	4.26E-05	167581	1902	tripartite motif containing 8	gene	biological_process-&-1&-GO:0010508-&&-positive regulation of autophagy-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0016567-&&-protein ubiquitination-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:TRIM8				TRIM8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM8	0.38035597	0.14761905	38	4	FALSE	TRIM8	TRIM8	121.6111111	0	37	0	0.72848065	FALSE	1	TRIM8	67702	0.05064815
791700	taxon:9606	2.51630692	3.58E-05	167317	1902	eukaryotic translation initiation factor 2A	gene	biological_process-&-1&-GO:1990928-&&-response to amino acid starvation-%%-GO:0032933-&&-SREBP signaling pathway-%%-GO:0006413-&&-translational initiation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0006417-&&-regulation of translation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0042255-&&-ribosome assembly|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005850-&&-eukaryotic translation initiation factor 2 complex-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0000049-&&-tRNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:EIF2A				EIF2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2A	0.3974078	0.14793741	38	4	FALSE	EIF2A	EIF2A	171.7105263	0	38	0	0.74728218	FALSE	0	EIF2A	70130	0.0555707
791904	taxon:9606	2.57113597	1.55E-04	182899	1902	amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase	gene	biological_process-&-1&-GO:0005980-&&-glycogen catabolic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0007584-&&-response to nutrient-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0016234-&&-inclusion body-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0043033-&&-isoamylase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004134-&&-4-alpha-glucanotransferase activity-%%-GO:0004135-&&-amylo-alpha-1,6-glucosidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030247-&&-polysaccharide binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0004133-&&-glycogen debranching enzyme activity	G:9606:AGL			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00500-&&-Starch and sucrose metabolism	AGL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGL	0.38893315	0.07539118	38	4	FALSE	AGL	AGL	168.131579	0	38	0	0.73814401	FALSE	0	AGL	201916	0.06140351
791963	taxon:9606	2.40649126	1.20E-04	182797	1902	annexin A5	gene	biological_process-&-1&-GO:0050819-&&-negative regulation of coagulation-%%-GO:0010033-&&-response to organic substance-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0007165-&&-signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane-%%-GO:0072563-&&-endothelial microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0004859-&&-phospholipase inhibitor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding	G:9606:ANXA5	ANXA5	TRUE		ANXA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA5	0.41554275	0.15504979	38	4	FALSE	ANXA5	ANXA5	257.7368421	0	38	0	0.76558479	FALSE	0	ANXA5	153310	0.06873139
792020	taxon:9606	2.56735466	8.35E-05	182721	1902	BLK proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:BLK				BLK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLK	0.38950598	0.10810811	38	4	FALSE	BLK	BLK	137.2631579	0	38	0	0.73877422	FALSE	0	BLK	111200	0.04992049
792036	taxon:9606	2.71120214	1.09E-04	182703	1902	bone morphogenetic protein receptor type 2	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0045906-&&-negative regulation of vasoconstriction-%%-GO:0061626-&&-pharyngeal arch artery morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0002063-&&-chondrocyte development-%%-GO:0014916-&&-regulation of lung blood pressure-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0048738-&&-cardiac muscle tissue development-%%-GO:0060350-&&-endochondral bone morphogenesis-%%-GO:0001893-&&-maternal placenta development-%%-GO:0060836-&&-lymphatic endothelial cell differentiation-%%-GO:1905314-&&-semi-lunar valve development-%%-GO:0048842-&&-positive regulation of axon extension involved in axon guidance-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0060173-&&-limb development-%%-GO:0003252-&&-negative regulation of cell proliferation involved in heart valve morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0048286-&&-lung alveolus development-%%-GO:0003186-&&-tricuspid valve morphogenesis-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0030166-&&-proteoglycan biosynthetic process-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0001707-&&-mesoderm formation-%%-GO:0007420-&&-brain development-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0060840-&&-artery development-%%-GO:1902731-&&-negative regulation of chondrocyte proliferation-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0003085-&&-negative regulation of systemic arterial blood pressure-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0060841-&&-venous blood vessel development-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0061036-&&-positive regulation of cartilage development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0044214-&&-spanning component of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0009986-&&-cell surface-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0030425-&&-dendrite-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0098821-&&-BMP receptor activity-%%-GO:0016362-&&-activin receptor activity, type II-%%-GO:0005524-&&-ATP binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0036122-&&-BMP binding	G:9606:BMPR2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	BMPR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMPR2	0.36884007	0.04285714	38	4	FALSE	BMPR2	BMPR2	77.27777778	0	37	0	0.71479964	FALSE	1	BMPR2	101230	0.04158395
792126	taxon:9606	2.49283126	1.23E-04	182549	1902	acid phosphatase 1, soluble	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003993-&&-acid phosphatase activity	G:9606:ACP1			KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04520-&&-Adherens junction	ACP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACP1	0.4011503	0.12539683	38	4	FALSE	ACP1	ACP1	222.9722222	0	37	0	0.75119479	FALSE	1	ACP1	167500	0.06954412
792308	taxon:9606	2.54324878	8.35E-05	182250	1902	centromere protein B	gene	cellular_component-&-1&-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0005694-&&-chromosome-%%-GO:0016604-&&-nuclear body-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0000775-&&-chromosome, centromeric region|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003696-&&-satellite DNA binding-%%-GO:0019237-&&-centromeric DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:CENPB				CENPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPB	0.39319787	0.06507937	38	4	FALSE	CENPB	CENPB	156.3055556	0	37	0	0.74279187	FALSE	1	CENPB	110650	0.05383082
792390	taxon:9606	2.7876162	4.71E-05	182101	1902	cysteine rich protein 1	gene	biological_process-&-1&-GO:0006955-&&-immune response-%%-GO:0007507-&&-heart development-%%-GO:0008283-&&-cell proliferation-%%-GO:0010043-&&-response to zinc ion-%%-GO:0060741-&&-prostate gland stromal morphogenesis-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0010033-&&-response to organic substance|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003680-&&-AT DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042277-&&-peptide binding-%%-GO:0008301-&&-DNA binding, bending	G:9606:CRIP1				CRIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRIP1	0.35872944	0.13513514	38	4	FALSE	CRIP1	CRIP1	76.05263158	0	38	0	0.70206397	FALSE	0	CRIP1	54060	0.05250427
792554	taxon:9606	2.7496455	5.76E-05	165433	1902	ring finger protein 166	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding	G:9606:RNF166				RNF166	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF166	0.36368325	0.06116643	38	4	FALSE	RNF166	RNF166	79.97368421	0	38	0	0.70839242	FALSE	0	RNF166	67624	0.04778103
792666	taxon:9606	2.67354656	1.44E-04	181592	1902	dystroglycan 1	gene	biological_process-&-1&-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0031103-&&-axon regeneration-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0021682-&&-nerve maturation-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0071711-&&-basement membrane organization-%%-GO:0016476-&&-regulation of embryonic cell shape-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0071397-&&-cellular response to cholesterol-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0016340-&&-calcium-dependent cell-matrix adhesion-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0002011-&&-morphogenesis of an epithelial sheet-%%-GO:0007568-&&-aging-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0071679-&&-commissural neuron axon guidance-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis-%%-GO:0010470-&&-regulation of gastrulation-%%-GO:1904261-&&-positive regulation of basement membrane assembly involved in embryonic body morphogenesis-%%-GO:0043409-&&-negative regulation of MAPK cascade|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0005604-&&-basement membrane-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005829-&&-cytosol-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0030027-&&-lamellipodium-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016011-&&-dystroglycan complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0070938-&&-contractile ring-%%-GO:0030175-&&-filopodium-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043034-&&-costamere-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0033268-&&-node of Ranvier-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0042383-&&-sarcolemma-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043237-&&-laminin-1 binding-%%-GO:0003779-&&-actin binding-%%-GO:0017166-&&-vinculin binding-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0015631-&&-tubulin binding-%%-GO:0001618-&&-virus receptor activity	G:9606:DAG1			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05416-&&-Viral myocarditis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	DAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAG1	0.37403501	0.10634921	38	4	FALSE	DAG1	DAG1	112.0555556	0	37	0	0.72107557	FALSE	1	DAG1	148256	0.05402429
792948	taxon:9606	2.64156294	4.95E-05	181096	1902	fructose-bisphosphatase 1	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0071286-&&-cellular response to magnesium ion-%%-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0005986-&&-sucrose biosynthetic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006111-&&-regulation of gluconeogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0048029-&&-monosaccharide binding-%%-GO:0042132-&&-fructose 1,6-bisphosphate 1-phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0016208-&&-AMP binding-%%-GO:0046872-&&-metal ion binding	G:9606:FBP1			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00030-&&-Pentose phosphate pathway	FBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBP1	0.37856376	0.07619048	38	4	FALSE	FBP1	FBP1	114.5833333	0	37	0	0.72640618	FALSE	1	FBP1	74174	0.0499418
792951	taxon:9606	2.60280447	2.01E-04	181088	1902	fibroblast growth factor receptor 2	gene	biological_process-&-1&-GO:0035603-&&-fibroblast growth factor receptor signaling pathway involved in hemopoiesis-%%-GO:0060595-&&-fibroblast growth factor receptor signaling pathway involved in mammary gland specification-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0033688-&&-regulation of osteoblast proliferation-%%-GO:0048562-&&-embryonic organ morphogenesis-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0045165-&&-cell fate commitment-%%-GO:0035602-&&-fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0051150-&&-regulation of smooth muscle cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016331-&&-morphogenesis of embryonic epithelium-%%-GO:0010453-&&-regulation of cell fate commitment-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0009791-&&-post-embryonic development-%%-GO:0060174-&&-limb bud formation-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0022612-&&-gland morphogenesis-%%-GO:0001657-&&-ureteric bud development-%%-GO:0060442-&&-branching involved in prostate gland morphogenesis-%%-GO:0060512-&&-prostate gland morphogenesis-%%-GO:0060667-&&-branch elongation involved in salivary gland morphogenesis-%%-GO:0060523-&&-prostate epithelial cord elongation-%%-GO:0035604-&&-fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0048608-&&-reproductive structure development-%%-GO:0007409-&&-axonogenesis-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0060615-&&-mammary gland bud formation-%%-GO:0030901-&&-midbrain development-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0032808-&&-lacrimal gland development-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001525-&&-angiogenesis-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0048730-&&-epidermis morphogenesis-%%-GO:0048755-&&-branching morphogenesis of a nerve-%%-GO:0060688-&&-regulation of morphogenesis of a branching structure-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0048565-&&-digestive tract development-%%-GO:0048568-&&-embryonic organ development-%%-GO:0060601-&&-lateral sprouting from an epithelium-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0060463-&&-lung lobe morphogenesis-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0060484-&&-lung-associated mesenchyme development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis-%%-GO:0042476-&&-odontogenesis-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0040036-&&-regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0048286-&&-lung alveolus development-%%-GO:0060348-&&-bone development-%%-GO:0060529-&&-squamous basal epithelial stem cell differentiation involved in prostate gland acinus development-%%-GO:0060916-&&-mesenchymal cell proliferation involved in lung development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030282-&&-bone mineralization-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0035265-&&-organ growth-%%-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0035607-&&-fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0021769-&&-orbitofrontal cortex development-%%-GO:0030324-&&-lung development-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0060915-&&-mesenchymal cell differentiation involved in lung development-%%-GO:0021847-&&-ventricular zone neuroblast division-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0021860-&&-pyramidal neuron development-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0010518-&&-positive regulation of phospholipase activity-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0060076-&&-excitatory synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005007-&&-fibroblast growth factor-activated receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:FGFR2	FGFR2	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05226-&&-Gastric cancer	FGFR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGFR2	0.38420097	0.0984127	38	4	FALSE	FGFR2	FGFR2	125.0555556	0	37	0	0.73286592	FALSE	1	FGFR2	178232	0.04947813
792954	taxon:9606	2.63084922	1.38E-04	181090	1902	fibroblast growth factor receptor 3	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0048640-&&-negative regulation of developmental growth-%%-GO:0001501-&&-skeletal system development-%%-GO:0001958-&&-endochondral ossification-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:1902178-&&-fibroblast growth factor receptor apoptotic signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070977-&&-bone maturation-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0003416-&&-endochondral bone growth-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0010518-&&-positive regulation of phospholipase activity-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035988-&&-chondrocyte proliferation-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0030282-&&-bone mineralization-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0030133-&&-transport vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005007-&&-fibroblast growth factor-activated receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity	G:9606:FGFR3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	FGFR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGFR3	0.3801054	0.06666667	38	4	FALSE	FGFR3	FGFR3	121.3333333	0	37	0	0.7281918	FALSE	1	FGFR3	134824	0.05148936
792955	taxon:9606	2.85930361	8.07E-05	181085	1902	fibrinogen like 1	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005577-&&-fibrinogen complex	G:9606:FGL1				FGL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGL1	0.34973551	0.00952381	38	4	FALSE	FGL1	FGL1	38.19444444	0	37	0	0.69011607	FALSE	1	FGL1	80626	0.03693619
792973	taxon:9606	2.63179455	9.19E-05	181061	1902	forkhead box C1	gene	biological_process-&-1&-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:1901491-&&-negative regulation of lymphangiogenesis-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0016477-&&-cell migration-%%-GO:0036438-&&-maintenance of lens transparency-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0046620-&&-regulation of organ growth-%%-GO:1902257-&&-negative regulation of apoptotic process involved in outflow tract morphogenesis-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043010-&&-camera-type eye development-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0001654-&&-eye development-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0032808-&&-lacrimal gland development-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:1901534-&&-positive regulation of hematopoietic progenitor cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0008354-&&-germ cell migration-%%-GO:0001945-&&-lymph vessel development-%%-GO:0048341-&&-paraxial mesoderm formation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:1902038-&&-positive regulation of hematopoietic stem cell differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001756-&&-somitogenesis-%%-GO:0007420-&&-brain development-%%-GO:0001503-&&-ossification-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0038084-&&-vascular endothelial growth factor signaling pathway-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0001657-&&-ureteric bud development-%%-GO:0008283-&&-cell proliferation-%%-GO:0014032-&&-neural crest cell development-%%-GO:0001501-&&-skeletal system development-%%-GO:0030203-&&-glycosaminoglycan metabolic process|cellular_component-&-1&-GO:0005720-&&-nuclear heterochromatin-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:FOXC1				FOXC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXC1	0.37996887	0.09246088	38	4	FALSE	FOXC1	FOXC1	126.9736842	0	38	0	0.72803424	FALSE	0	FOXC1	125112	0.05312727
793274	taxon:9606	2.6051678	1.38E-05	180385	1902	histone cluster 1 H1 family member e	gene	biological_process-&-1&-GO:0016584-&&-nucleosome positioning-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0080182-&&-histone H3-K4 trimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005720-&&-nuclear heterochromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1E				HIST1H1E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1E	0.38385243	0.36130868	38	4	FALSE	HIST1H1E	HIST1H1E	274.8157895	0	38	0	0.73247203	FALSE	0	HIST1H1E	57062	0.1075497
793331	taxon:9606	2.42350717	6.51E-05	180311	1902	hexokinase 1	gene	biological_process-&-1&-GO:0051156-&&-glucose 6-phosphate metabolic process-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0072655-&&-establishment of protein localization to mitochondrion-%%-GO:0072656-&&-maintenance of protein location in mitochondrion-%%-GO:0015758-&&-glucose transport-%%-GO:0006096-&&-glycolytic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0046835-&&-carbohydrate phosphorylation|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0097228-&&-sperm principal piece-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0004396-&&-hexokinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008865-&&-fructokinase activity-%%-GO:0004340-&&-glucokinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019158-&&-mannokinase activity-%%-GO:0005536-&&-glucose binding	G:9606:HK1	HK1	TRUE	KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00524-&&-Neomycin, kanamycin and gentamicin biosynthesis-%%-hsa04066-&&-HIF-1 signaling pathway	HK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HK1	0.41262515	0.13655761	38	4	FALSE	HK1	HK1	217.1052632	0	38	0	0.76274881	FALSE	0	HK1	115894	0.05936888
787256	taxon:9606	2.66614148	1.03E-04	179794	1902	inosine triphosphatase	gene	biological_process-&-1&-GO:0055086-&&-nucleobase-containing small molecule metabolic process-%%-GO:0006193-&&-ITP catabolic process-%%-GO:0051276-&&-chromosome organization-%%-GO:0009143-&&-nucleoside triphosphate catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0035529-&&-NADH pyrophosphatase activity-%%-GO:0035870-&&-dITP diphosphatase activity-%%-GO:0036220-&&-ITP diphosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0047429-&&-nucleoside-triphosphate diphosphatase activity-%%-GO:0036222-&&-XTP diphosphatase activity-%%-GO:0042802-&&-identical protein binding	G:9606:ITPA			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	ITPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITPA	0.37507387	0.07394958	37	4	FALSE	ITPA	ITPA	103.6571429	0	36	0	0.72230975	FALSE	1	ITPA	97846	0.04789254
787336	taxon:9606	2.51173783	9.53E-05	179640	1902	kinectin 1	gene	biological_process-&-1&-GO:0007018-&&-microtubule-based movement|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:KTN1				KTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KTN1	0.39813072	0.07507508	37	4	FALSE	KTN1	KTN1	168.2162162	0	37	0	0.7480437	FALSE	0	KTN1	149644	0.05435115
787497	taxon:9606	2.59350874	1.08E-04	162953	1902	abnormal spindle microtubule assembly	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0001764-&&-neuron migration-%%-GO:0051653-&&-spindle localization-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0021873-&&-forebrain neuroblast division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0090306-&&-spindle assembly involved in meiosis-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0048589-&&-developmental growth-%%-GO:0007051-&&-spindle organization-%%-GO:0051445-&&-regulation of meiotic cell cycle-%%-GO:0045769-&&-negative regulation of asymmetric cell division-%%-GO:0051661-&&-maintenance of centrosome location-%%-GO:0008584-&&-male gonad development-%%-GO:0048477-&&-oogenesis-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0072687-&&-meiotic spindle-%%-GO:0005634-&&-nucleus-%%-GO:0097431-&&-mitotic spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0036449-&&-microtubule minus-end|molecular_function-&-1&-GO:0005516-&&-calmodulin binding	G:9606:ASPM				ASPM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASPM	0.38557803	0.04054054	37	4	FALSE	ASPM	ASPM	121.8378378	0	37	0	0.73441521	FALSE	0	ASPM	126334	0.04642204
787574	taxon:9606	2.79848747	4.98E-05	179155	1902	NADH:ubiquinone oxidoreductase subunit S6	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0072358-&&-cardiovascular system development-%%-GO:0061458-&&-reproductive system development-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0035264-&&-multicellular organism growth|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0009055-&&-electron carrier activity	G:9606:NDUFS6			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS6	0.35733589	0.22672673	37	4	FALSE	NDUFS6	NDUFS6	71.97297297	0	37	0	0.70025209	FALSE	0	NDUFS6	53232	0.05120099
787584	taxon:9606	2.53647392	1.05E-04	179141	1902	neurofilament light	gene	biological_process-&-1&-GO:0008089-&&-anterograde axonal transport-%%-GO:0051412-&&-response to corticosterone-%%-GO:0031133-&&-regulation of axon diameter-%%-GO:0045105-&&-intermediate filament polymerization or depolymerization-%%-GO:0021766-&&-hippocampus development-%%-GO:1903937-&&-response to acrylamide-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0021510-&&-spinal cord development-%%-GO:0009636-&&-response to toxic substance-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0033693-&&-neurofilament bundle assembly-%%-GO:0014012-&&-peripheral nervous system axon regeneration-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0040011-&&-locomotion-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051258-&&-protein polymerization-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:1903935-&&-response to sodium arsenite-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0050772-&&-positive regulation of axonogenesis|cellular_component-&-1&-GO:0033596-&&-TSC1-TSC2 complex-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005883-&&-neurofilament|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043274-&&-phospholipase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:NEFL			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	NEFL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEFL	0.39424809	0.07563025	37	4	FALSE	NEFL	NEFL	163.9142857	0	36	0	0.74392101	FALSE	1	NEFL	140564	0.05533662
787668	taxon:9606	2.60233181	7.58E-05	178990	1902	serpin family B member 5	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0060512-&&-prostate gland morphogenesis-%%-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0050678-&&-regulation of epithelial cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINB5			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer	SERPINB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB5	0.38427075	0.06606607	37	4	FALSE	SERPINB5	SERPINB5	122.2162162	0	37	0	0.7329447	FALSE	0	SERPINB5	102138	0.04832527
787696	taxon:9606	2.58247991	7.78E-05	178925	1902	phospholipase D1	gene	biological_process-&-1&-GO:0048870-&&-cell motility-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0048017-&&-inositol lipid-mediated signaling-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0006935-&&-chemotaxis-%%-GO:0032534-&&-regulation of microvillus assembly-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004630-&&-phospholipase D activity-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0070290-&&-N-acylphosphatidylethanolamine-specific phospholipase D activity	G:9606:PLD1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04144-&&-Endocytosis-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05200-&&-Pathways in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	PLD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLD1	0.3872247	0.09747899	37	4	FALSE	PLD1	PLD1	134.2571429	0	36	0	0.73625335	FALSE	1	PLD1	101516	0.05036775
787746	taxon:9606	2.57223885	0.0012434	178845	1902	cytochrome p450 oxidoreductase	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0009437-&&-carnitine metabolic process-%%-GO:0003420-&&-regulation of growth plate cartilage chondrocyte proliferation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0090031-&&-positive regulation of steroid hormone biosynthetic process-%%-GO:0070988-&&-demethylation-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0032770-&&-positive regulation of monooxygenase activity-%%-GO:0045542-&&-positive regulation of cholesterol biosynthetic process-%%-GO:0046210-&&-nitric oxide catabolic process-%%-GO:0060192-&&-negative regulation of lipase activity-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0007584-&&-response to nutrient-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043602-&&-nitrate catabolic process-%%-GO:0009812-&&-flavonoid metabolic process-%%-GO:0018393-&&-internal peptidyl-lysine acetylation-%%-GO:0042493-&&-response to drug-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0090346-&&-cellular organofluorine metabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0004128-&&-cytochrome-b5 reductase activity, acting on NAD(P)H-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0047726-&&-iron-cytochrome-c reductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0010181-&&-FMN binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0050661-&&-NADP binding-%%-GO:0008941-&&-nitric oxide dioxygenase activity	G:9606:POR	POR	TRUE		POR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POR	0.38876638	0.06906907	37	4	FALSE	POR	POR	119.6486487	0	37	0	0.73796019	FALSE	0	POR	1062098	0.04359611
787776	taxon:9606	2.40885458	7.55E-05	178803	1902	protein phosphatase 2 regulatory subunit B'gamma	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007165-&&-signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019888-&&-protein phosphatase regulator activity	G:9606:PPP2R5C			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R5C	0.41513506	0.19369369	37	4	FALSE	PPP2R5C	PPP2R5C	212.8648649	0	37	0	0.7651909	FALSE	0	PPP2R5C	120226	0.05677262
787782	taxon:9606	2.42776115	3.08E-05	178793	1902	protein phosphatase 6 catalytic subunit	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP6C				PPP6C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP6C	0.41190214	0.16516517	37	4	FALSE	PPP6C	PPP6C	247.5675676	0	37	0	0.76203981	FALSE	0	PPP6C	97506	0.06800564
787908	taxon:9606	2.630219	2.04E-04	178628	1902	patched 1	gene	biological_process-&-1&-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007420-&&-brain development-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0060831-&&-smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0071397-&&-cellular response to cholesterol-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0009957-&&-epidermal cell fate specification-%%-GO:0016485-&&-protein processing-%%-GO:0001709-&&-cell fate determination-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0021532-&&-neural tube patterning-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0042493-&&-response to drug-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0072001-&&-renal system development-%%-GO:0048568-&&-embryonic organ development-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0045606-&&-positive regulation of epidermal cell differentiation-%%-GO:0072203-&&-cell proliferation involved in metanephros development-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0061053-&&-somite development-%%-GO:0010157-&&-response to chlorate-%%-GO:0032355-&&-response to estradiol-%%-GO:0040015-&&-negative regulation of multicellular organism growth-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0035137-&&-hindlimb morphogenesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0061005-&&-cell differentiation involved in kidney development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035108-&&-limb morphogenesis-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0060603-&&-mammary gland duct morphogenesis-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0021997-&&-neural plate axis specification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030496-&&-midbody-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0044294-&&-dendritic growth cone-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0016021-&&-integral component of membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0005901-&&-caveola-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0044295-&&-axonal growth cone|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0008158-&&-hedgehog receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0097108-&&-hedgehog family protein binding-%%-GO:0005113-&&-patched binding-%%-GO:0005119-&&-smoothened binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008201-&&-heparin binding	G:9606:PTCH1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05217-&&-Basal cell carcinoma	PTCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTCH1	0.38019648	0.03003003	37	4	FALSE	PTCH1	PTCH1	103.027027	0	37	0	0.72829683	FALSE	0	PTCH1	174790	0.04379048
788091	taxon:9606	2.55065385	3.67E-05	178259	1902	phosphoglycerate mutase 1	gene	biological_process-&-1&-GO:0006094-&&-gluconeogenesis-%%-GO:0043456-&&-regulation of pentose-phosphate shunt-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0045730-&&-respiratory burst-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006096-&&-glycolytic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016787-&&-hydrolase activity-%%-GO:0004082-&&-bisphosphoglycerate mutase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0046538-&&-2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity-%%-GO:0004619-&&-phosphoglycerate mutase activity	G:9606:PGAM1			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00260-&&-Glycine, serine and threonine metabolism	PGAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGAM1	0.39205633	0.17142857	37	4	FALSE	PGAM1	PGAM1	166.2857143	0	36	0	0.74155769	FALSE	1	PGAM1	71802	0.05772817
788156	taxon:9606	2.79549393	5.92E-05	178148	1902	Rab geranylgeranyltransferase beta subunit	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0018344-&&-protein geranylgeranylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005968-&&-Rab-protein geranylgeranyltransferase complex|molecular_function-&-1&-GO:0004663-&&-Rab geranylgeranyltransferase activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RABGGTB				RABGGTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABGGTB	0.35771854	0.02521008	37	4	FALSE	RABGGTB	RABGGTB	52.68571429	0	36	0	0.70075101	FALSE	1	RABGGTB	51834	0.03886994
788408	taxon:9606	2.72553963	6.44E-05	177727	1902	syntaxin 1A	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0048278-&&-vesicle docking-%%-GO:0072657-&&-protein localization to membrane-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0009629-&&-response to gravity-%%-GO:0033605-&&-positive regulation of catecholamine secretion-%%-GO:0016081-&&-synaptic vesicle docking-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0001956-&&-positive regulation of neurotransmitter secretion-%%-GO:0032940-&&-secretion by cell-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0010807-&&-regulation of synaptic vesicle priming-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0010701-&&-positive regulation of norepinephrine secretion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0031201-&&-SNARE complex-%%-GO:0070033-&&-synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex-%%-GO:0042641-&&-actomyosin-%%-GO:0070044-&&-synaptobrevin 2-SNAP-25-syntaxin-1a complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030141-&&-secretory granule-%%-GO:0048787-&&-presynaptic active zone membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0070032-&&-synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex-%%-GO:0030672-&&-synaptic vesicle membrane|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0032028-&&-myosin head/neck binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0043008-&&-ATP-dependent protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019869-&&-chloride channel inhibitor activity-%%-GO:0017022-&&-myosin binding-%%-GO:0019900-&&-kinase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019855-&&-calcium channel inhibitor activity	G:9606:STX1A			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04911-&&-Insulin secretion-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05031-&&-Amphetamine addiction	STX1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX1A	0.36689982	0.06554622	37	5	FALSE	STX1A	STX1A	79.94285714	0	36	0	0.71241006	FALSE	1	STX1A	70358	0.0444923
788762	taxon:9606	2.47928155	1.47E-05	160605	1902	actin, beta like 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:ACTBL2				ACTBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTBL2	0.40334265	0.18168168	37	4	FALSE	ACTBL2	ACTBL2	294.7027027	0	37	0	0.75345307	FALSE	0	ACTBL2	57884	0.08911725
788786	taxon:9606	2.66456594	1.28E-04	160526	1902	tubulin beta 8 class VIII	gene	biological_process-&-1&-GO:0007056-&&-spindle assembly involved in female meiosis-%%-GO:0001556-&&-oocyte maturation-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072687-&&-meiotic spindle-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003674-&&-molecular_function-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBB8			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB8	0.37529565	0.05855856	37	4	FALSE	TUBB8	TUBB8	105.0810811	0	37	0	0.72257234	FALSE	0	TUBB8	146140	0.0480577
788983	taxon:9606	2.4592721	4.79E-05	176460	1902	coiled-coil domain containing 6	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:CCDC6			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	CCDC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC6	0.40662438	0.15465465	37	4	FALSE	CCDC6	CCDC6	210.4864865	0	37	0	0.75678798	FALSE	0	CCDC6	87916	0.06066862
789043	taxon:9606	2.63147944	5.45E-05	176310	1902	BRCA1 associated protein	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0008270-&&-zinc ion binding	G:9606:BRAP			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	BRAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRAP	0.38001437	0.08067227	37	4	FALSE	BRAP	BRAP	130.1714286	0	36	0	0.72808676	FALSE	1	BRAP	75606	0.05528267
789090	taxon:9606	2.47329447	9.28E-05	176209	1902	Rho guanine nucleotide exchange factor 7	gene	biological_process-&-1&-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0007399-&&-nervous system development-%%-GO:0007165-&&-signal transduction-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0007030-&&-Golgi organization-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:1904424-&&-regulation of GTP binding-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0043025-&&-neuronal cell body-%%-GO:0001726-&&-ruffle-%%-GO:0043234-&&-protein complex-%%-GO:0000322-&&-storage vacuole-%%-GO:0043005-&&-neuron projection-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:ARHGEF7			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	ARHGEF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF7	0.40431902	0.18468468	37	4	FALSE	ARHGEF7	ARHGEF7	181.5135135	0	37	0	0.75445092	FALSE	0	ARHGEF7	130748	0.05430475
789116	taxon:9606	2.69844021	5.64E-05	176165	1902	forkhead box H1	gene	biological_process-&-1&-GO:0035054-&&-embryonic heart tube anterior/posterior pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048318-&&-axial mesoderm development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:2000824-&&-negative regulation of androgen receptor activity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:1900164-&&-nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0001947-&&-heart looping|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0032444-&&-activin responsive factor complex|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0070412-&&-R-SMAD binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0035326-&&-enhancer binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003677-&&-DNA binding	G:9606:FOXH1				FOXH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXH1	0.37058446	0.06156156	37	4	FALSE	FOXH1	FOXH1	97.27027027	0	37	0	0.71692663	FALSE	0	FOXH1	70518	0.04915498
789121	taxon:9606	2.55679849	2.59E-04	176158	1902	WAS protein family member 1	gene	biological_process-&-1&-GO:2000601-&&-positive regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:1990416-&&-cellular response to brain-derived neurotrophic factor stimulus-%%-GO:0097484-&&-dendrite extension-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0072673-&&-lamellipodium morphogenesis-%%-GO:0051388-&&-positive regulation of neurotrophin TRK receptor signaling pathway|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005925-&&-focal adhesion-%%-GO:0031209-&&-SCAR complex-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0030027-&&-lamellipodium|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0032403-&&-protein complex binding	G:9606:WASF1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04520-&&-Adherens junction-%%-hsa05131-&&-Shigellosis	WASF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WASF1	0.39111412	0.18768769	37	4	FALSE	WASF1	WASF1	148.6216216	0	37	0	0.74053359	FALSE	0	WASF1	334458	0.05289946
789147	taxon:9606	2.60910666	1.31E-04	176104	1902	aryl hydrocarbon receptor interacting protein	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0022417-&&-protein maturation by protein folding-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0007165-&&-signal transduction-%%-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0051344-&&-negative regulation of cyclic-nucleotide phosphodiesterase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034751-&&-aryl hydrocarbon receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0017162-&&-aryl hydrocarbon receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0036004-&&-GAF domain binding	G:9606:AIP			KEGG-&-1&-hsa04934-&&-Cushing syndrome	AIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIP	0.38327295	0.08108108	37	4	FALSE	AIP	AIP	113.1621622	0	37	0	0.73181556	FALSE	0	AIP	130720	0.04524348
789340	taxon:9606	2.66866236	7.40E-05	175707	1902	synaptosome associated protein 23	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0002553-&&-histamine secretion by mast cell-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006903-&&-vesicle targeting-%%-GO:0016082-&&-synaptic vesicle priming|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0042582-&&-azurophil granule-%%-GO:0098793-&&-presynapse-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0042581-&&-specific granule-%%-GO:0042629-&&-mast cell granule-%%-GO:0005925-&&-focal adhesion-%%-GO:0031201-&&-SNARE complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding	G:9606:SNAP23			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04611-&&-Platelet activation	SNAP23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAP23	0.37471957	0.1210084	37	4	FALSE	SNAP23	SNAP23	109.2857143	0	36	0	0.72188961	FALSE	1	SNAP23	86044	0.0511236
789351	taxon:9606	2.53285017	7.49E-05	175686	1902	rabaptin, RAB GTPase binding effector protein 1	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0006897-&&-endocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0031901-&&-early endosome membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0055037-&&-recycling endosome-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:RABEP1			KEGG-&-1&-hsa04144-&&-Endocytosis	RABEP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABEP1	0.39481214	0.09915966	37	4	FALSE	RABEP1	RABEP1	160.8857143	0	36	0	0.74452497	FALSE	1	RABEP1	100152	0.05396825
789581	taxon:9606	2.48463841	9.06E-05	175138	1902	TBC1 domain family member 4	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport-%%-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0061024-&&-membrane organization-%%-GO:0031339-&&-negative regulation of vesicle fusion-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D4			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04931-&&-Insulin resistance	TBC1D4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D4	0.40247305	0.10510511	37	4	FALSE	TBC1D4	TBC1D4	195.2162162	0	37	0	0.75256026	FALSE	0	TBC1D4	128678	0.05955024
789610	taxon:9606	2.59744761	1.77E-05	175057	1902	nuclear receptor subfamily 1 group H member 4	gene	biological_process-&-1&-GO:0055089-&&-fatty acid homeostasis-%%-GO:1904179-&&-positive regulation of adipose tissue development-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:2000213-&&-positive regulation of glutamate metabolic process-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:1905695-&&-positive regulation of phosphatidic acid biosynthetic process-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:2001250-&&-positive regulation of ammonia assimilation cycle-%%-GO:0010988-&&-regulation of low-density lipoprotein particle clearance-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006954-&&-inflammatory response-%%-GO:1904468-&&-negative regulation of tumor necrosis factor secretion-%%-GO:0034971-&&-histone H3-R17 methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032692-&&-negative regulation of interleukin-1 production-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0038183-&&-bile acid signaling pathway-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0035356-&&-cellular triglyceride homeostasis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0034255-&&-regulation of urea metabolic process-%%-GO:0070858-&&-negative regulation of bile acid biosynthetic process-%%-GO:0007165-&&-signal transduction-%%-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0042742-&&-defense response to bacterium-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0038185-&&-intracellular bile acid receptor signaling pathway-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0072615-&&-interleukin-17 secretion-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0071417-&&-cellular response to organonitrogen compound-%%-GO:0008206-&&-bile acid metabolic process-%%-GO:0001080-&&-nitrogen catabolite activation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0070857-&&-regulation of bile acid biosynthetic process-%%-GO:0045087-&&-innate immune response-%%-GO:1902714-&&-negative regulation of interferon-gamma secretion-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0090181-&&-regulation of cholesterol metabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005719-&&-nuclear euchromatin|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0038181-&&-bile acid receptor activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:1902122-&&-chenodeoxycholic acid binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0032052-&&-bile acid binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:NR1H4			KEGG-&-1&-hsa04976-&&-Bile secretion	NR1H4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR1H4	0.38499333	0.37537538	37	4	FALSE	NR1H4	NR1H4	237.6756757	0	37	0	0.73375873	FALSE	0	NR1H4	52082	0.09232659
789684	taxon:9606	2.42949425	3.89E-05	174896	1902	eukaryotic translation initiation factor 3 subunit M	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0002183-&&-cytoplasmic translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex-%%-GO:0005829-&&-cytosol-%%-GO:0071541-&&-eukaryotic translation initiation factor 3 complex, eIF3m|molecular_function-&-1&-GO:0031369-&&-translation initiation factor binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:EIF3M				EIF3M	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3M	0.4116083	0.23723724	37	4	FALSE	EIF3M	EIF3M	222.945946	0	37	0	0.76175096	FALSE	0	EIF3M	94250	0.06159683
789686	taxon:9606	2.46651962	2.22E-04	174893	1902	Sec23 homolog B, coat complex II component	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030127-&&-COPII vesicle coat-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SEC23B			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC23B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC23B	0.40542958	0.14957983	37	4	FALSE	SEC23B	SEC23B	255.0857143	0	36	0	0.75558006	FALSE	1	SEC23B	285270	0.07524343
789688	taxon:9606	2.49204349	3.41E-05	174889	1902	adenylate cyclase associated protein 1	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007165-&&-signal transduction-%%-GO:0001667-&&-ameboidal-type cell migration-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0000902-&&-cell morphogenesis|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008179-&&-adenylate cyclase binding-%%-GO:0003779-&&-actin binding	G:9606:CAP1				CAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAP1	0.40127711	0.18319328	37	4	FALSE	CAP1	CAP1	213.4285714	0	36	0	0.75132609	FALSE	1	CAP1	67522	0.06603882
789725	taxon:9606	2.49487947	4.76E-05	174819	1902	sorbin and SH3 domain containing 1	gene	biological_process-&-1&-GO:0015758-&&-glucose transport-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0006936-&&-muscle contraction-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction|cellular_component-&-1&-GO:0005913-&&-cell-cell adherens junction-%%-GO:0005899-&&-insulin receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005915-&&-zonula adherens-%%-GO:0005924-&&-cell-substrate adherens junction-%%-GO:0045121-&&-membrane raft-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0001725-&&-stress fiber-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0005515-&&-protein binding	G:9606:SORBS1	SORBS1	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04520-&&-Adherens junction-%%-hsa03320-&&-PPAR signaling pathway	SORBS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SORBS1	0.40082097	0.18018018	37	4	FALSE	SORBS1	SORBS1	178.027027	0	37	0	0.75085342	FALSE	0	SORBS1	79052	0.05531386
789899	taxon:9606	2.4759729	6.79E-05	174406	1902	hexamethylene bisacetamide inducible 1	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007507-&&-heart development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1901798-&&-positive regulation of signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0017069-&&-snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:HEXIM1				HEXIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEXIM1	0.40388164	0.13963964	37	4	FALSE	HEXIM1	HEXIM1	185.5135135	0	37	0	0.75400452	FALSE	0	HEXIM1	104420	0.05574324
789938	taxon:9606	2.53741925	2.91E-05	174305	1902	mitogen-activated protein kinase kinase kinase 2	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAP3K2			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04912-&&-GnRH signaling pathway	MAP3K2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K2	0.39410121	0.23361345	37	4	FALSE	MAP3K2	MAP3K2	197.8285714	0	36	0	0.74376346	FALSE	1	MAP3K2	65046	0.06681141
790009	taxon:9606	2.56436112	6.61E-05	174120	1902	fibroblast growth factor receptor substrate 3	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005104-&&-fibroblast growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:FRS3				FRS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FRS3	0.38996068	0.10252101	37	4	FALSE	FRS3	FRS3	139.7142857	0	36	0	0.73927315	FALSE	1	FRS3	106644	0.05034259
790125	taxon:9606	2.52812352	3.74E-05	173817	1902	ataxin 2 like	gene	biological_process-&-1&-GO:0034063-&&-stress granule assembly-%%-GO:0010603-&&-regulation of cytoplasmic mRNA processing body assembly|cellular_component-&-1&-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:ATXN2L				ATXN2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN2L	0.39555029	0.18318318	37	4	FALSE	ATXN2L	ATXN2L	213.9189189	0	37	0	0.74531275	FALSE	0	ATXN2L	82600	0.07121379
790295	taxon:9606	2.65731842	3.32E-05	173400	1902	LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0008380-&&-RNA splicing-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000387-&&-spliceosomal snRNP assembly|cellular_component-&-1&-GO:0097526-&&-spliceosomal tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0043005-&&-neuron projection-%%-GO:0005688-&&-U6 snRNP-%%-GO:0000932-&&-P-body-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0017070-&&-U6 snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LSM4			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa03018-&&-RNA degradation	LSM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM4	0.37631922	0.10810811	37	4	FALSE	LSM4	LSM4	114.1621622	0	37	0	0.72378026	FALSE	0	LSM4	52758	0.05138787
790296	taxon:9606	2.47943911	6.17E-05	173393	1902	ataxin 10	gene	biological_process-&-1&-GO:0070207-&&-protein homotrimerization-%%-GO:0007399-&&-nervous system development-%%-GO:0031175-&&-neuron projection development-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0030425-&&-dendrite-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ATXN10				ATXN10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN10	0.40331702	0.1036036	37	4	FALSE	ATXN10	ATXN10	206.4054054	0	37	0	0.75342682	FALSE	0	ATXN10	114614	0.06251433
790328	taxon:9606	2.43548133	8.08E-05	173306	1902	protein tyrosine phosphatase, non-receptor type 23	gene	biological_process-&-1&-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:1903393-&&-positive regulation of adherens junction organization-%%-GO:0015031-&&-protein transport-%%-GO:1903387-&&-positive regulation of homophilic cell adhesion-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:PTPN23				PTPN23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN23	0.41059645	0.15915916	37	4	FALSE	PTPN23	PTPN23	221.1081081	0	37	0	0.76075311	FALSE	0	PTPN23	149714	0.06186791
790399	taxon:9606	2.56247046	1.06E-04	173117	1902	DNA polymerase alpha 2, accessory subunit	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006260-&&-DNA replication-%%-GO:0071897-&&-DNA biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005658-&&-alpha DNA polymerase:primase complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003887-&&-DNA-directed DNA polymerase activity	G:9606:POLA2			KEGG-&-1&-hsa03030-&&-DNA replication	POLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLA2	0.3902484	0.07207207	37	4	FALSE	POLA2	POLA2	131.8648649	0	37	0	0.73958826	FALSE	0	POLA2	121554	0.04732158
790521	taxon:9606	2.56073736	1.71E-04	172635	1902	MYC binding protein	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding	G:9606:MYCBP				MYCBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYCBP	0.39051252	0.17567568	37	4	FALSE	MYCBP	MYCBP	227.1891892	0	37	0	0.73987711	FALSE	0	MYCBP	277696	0.08110039
790566	taxon:9606	2.44477706	2.29E-05	172126	1902	A-kinase anchoring protein 8 like	gene	biological_process-&-1&-GO:0033127-&&-regulation of histone phosphorylation-%%-GO:0044839-&&-cell cycle G2/M phase transition-%%-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0051081-&&-nuclear envelope disassembly-%%-GO:0006397-&&-mRNA processing-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0008380-&&-RNA splicing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0016363-&&-nuclear matrix-%%-GO:0016605-&&-PML body-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0005521-&&-lamin binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:AKAP8L				AKAP8L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP8L	0.40903525	0.18151261	37	4	FALSE	AKAP8L	AKAP8L	292.1714286	0	36	0	0.75920382	FALSE	1	AKAP8L	68610	0.08277537
790607	taxon:9606	2.66251772	2.11E-05	171778	1902	mex-3 RNA binding family member C	gene	biological_process-&-1&-GO:0003415-&&-chondrocyte hypertrophy-%%-GO:0045598-&&-regulation of fat cell differentiation-%%-GO:0097009-&&-energy homeostasis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding	G:9606:MEX3C				MEX3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEX3C	0.37558435	0.06006006	37	4	FALSE	MEX3C	MEX3C	123	0	37	0	0.72291371	FALSE	0	MEX3C	41904	0.05598984
790626	taxon:9606	2.58893966	2.12E-05	171713	1902	anaphase promoting complex subunit 5	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding	G:9606:ANAPC5			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC5	0.38625852	0.26126126	37	4	FALSE	ANAPC5	ANAPC5	148.6486487	0	37	0	0.73517672	FALSE	0	ANAPC5	51818	0.05611501
790696	taxon:9606	2.45233969	3.61E-05	171446	1902	Obg like ATPase 1	gene	biological_process-&-1&-GO:0046034-&&-ATP metabolic process-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:OLA1				OLA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OLA1	0.40777385	0.18168168	37	4	FALSE	OLA1	OLA1	244.2432432	0	37	0	0.75794339	FALSE	0	OLA1	75810	0.07020189
790869	taxon:9606	2.89412321	3.23E-05	170824	1902	protein arginine methyltransferase 7	gene	biological_process-&-1&-GO:0019918-&&-peptidyl-arginine methylation, to symmetrical-dimethyl arginine-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0018216-&&-peptidyl-arginine methylation-%%-GO:0016571-&&-histone methylation-%%-GO:0043985-&&-histone H4-R3 methylation-%%-GO:0034969-&&-histone arginine methylation-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0043393-&&-regulation of protein binding|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0008469-&&-histone-arginine N-methyltransferase activity-%%-GO:0016277-&&-[myelin basic protein]-arginine N-methyltransferase activity-%%-GO:0044020-&&-histone methyltransferase activity (H4-R3 specific)-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0035243-&&-protein-arginine omega-N symmetric methyltransferase activity-%%-GO:0042393-&&-histone binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0035241-&&-protein-arginine omega-N monomethyltransferase activity	G:9606:PRMT7				PRMT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRMT7	0.34552779	0.31381381	37	4	FALSE	PRMT7	PRMT7	205.3243243	0	37	0	0.6843128	FALSE	0	PRMT7	85292	0.21855011
790894	taxon:9606	2.76177722	2.80E-05	170749	1902	ubiquitin-fold modifier conjugating enzyme 1	gene	biological_process-&-1&-GO:0071569-&&-protein ufmylation-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0071568-&&-UFM1 transferase activity	G:9606:UFC1				UFC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFC1	0.36208569	0.17567568	37	4	FALSE	UFC1	UFC1	87.16216216	0	37	0	0.70637046	FALSE	0	UFC1	41802	0.05440856
790943	taxon:9606	2.54829053	2.27E-05	170651	1902	ankyrin repeat and SOCS box containing 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:ASB2				ASB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB2	0.39241993	0.18991597	37	4	FALSE	ASB2	ASB2	210.7428571	0	36	0	0.74195158	FALSE	1	ASB2	61942	0.07274073
790993	taxon:9606	2.45596345	3.87E-05	170468	1902	ring finger and WD repeat domain 3	gene	biological_process-&-1&-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0097371-&&-MDM2/MDM4 family protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RFWD3				RFWD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFWD3	0.40717218	0.13963964	37	4	FALSE	RFWD3	RFWD3	222.945946	0	37	0	0.75733943	FALSE	0	RFWD3	93408	0.06467658
791110	taxon:9606	2.75909879	3.64E-05	170005	1902	coordinator of PRMT5 and differentiation stimulator	gene	biological_process-&-1&-GO:0043985-&&-histone H4-R3 methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007517-&&-muscle organ development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding	G:9606:COPRS				COPRS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPRS	0.36243719	0.34684685	37	4	FALSE	COPRS	COPRS	247	0	37	0	0.70681687	FALSE	0	COPRS	67832	0.15146742
791181	taxon:9606	2.54970852	9.19E-05	169800	1902	ADP ribosylation factor GTPase activating protein 1	gene	biological_process-&-1&-GO:0030100-&&-regulation of endocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:ARFGAP1			KEGG-&-1&-hsa04144-&&-Endocytosis	ARFGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGAP1	0.39220169	0.06156156	37	4	FALSE	ARFGAP1	ARFGAP1	139.8918919	0	37	0	0.74171525	FALSE	0	ARFGAP1	128032	0.04896516
791269	taxon:9606	2.69922798	2.37E-05	169428	1902	AT-rich interaction domain 1B	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0048096-&&-chromatin-mediated maintenance of transcription-%%-GO:0007270-&&-neuron-neuron synaptic transmission-%%-GO:0097026-&&-dendritic cell dendrite assembly-%%-GO:0060996-&&-dendritic spine development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0071565-&&-nBAF complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding	G:9606:ARID1B			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	ARID1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARID1B	0.3704763	0.25714286	37	4	FALSE	ARID1B	ARID1B	128.3714286	0	36	0	0.71679534	FALSE	1	ARID1B	45832	0.06460941
791423	taxon:9606	2.51473137	3.91E-05	168697	1902	mitochondrial ribosomal protein L38	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005743-&&-mitochondrial inner membrane	G:9606:MRPL38				MRPL38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL38	0.39765679	0.17567568	37	4	FALSE	MRPL38	MRPL38	195.3783784	0	37	0	0.74754477	FALSE	0	MRPL38	83308	0.06316507
791556	taxon:9606	2.55648338	5.64E-05	168049	1902	centrosomal protein 97	gene	biological_process-&-1&-GO:1902018-&&-negative regulation of cilium assembly-%%-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:CEP97				CEP97	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP97	0.39116233	0.2012012	37	4	FALSE	CEP97	CEP97	150.1891892	0	37	0	0.7405861	FALSE	0	CEP97	87996	0.05265153
791605	taxon:9606	2.59020009	7.75E-05	167859	1902	potassium channel tetramerization domain containing 17	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0030030-&&-cell projection organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0045724-&&-positive regulation of cilium assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0097602-&&-cullin family protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KCTD17				KCTD17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCTD17	0.38607056	0.04705882	37	4	FALSE	KCTD17	KCTD17	128.6285714	0	36	0	0.73496665	FALSE	1	KCTD17	99252	0.04895623
791698	taxon:9606	2.51063495	1.16E-04	167379	1902	tubulin beta 1 class VI	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBB1			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome	TUBB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBB1	0.39830562	0.16966967	37	4	FALSE	TUBB1	TUBB1	234.9189189	0	37	0	0.74822751	FALSE	0	TUBB1	140728	0.07536332
791716	taxon:9606	2.71230503	1.34E-05	167216	1902	mediator complex subunit 25	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:2001178-&&-positive regulation of mediator complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048147-&&-negative regulation of fibroblast proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0044798-&&-nuclear transcription factor complex|molecular_function-&-1&-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:MED25				MED25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED25	0.3686901	0.44537815	37	4	FALSE	MED25	MED25	113.4857143	0	36	0	0.71461583	FALSE	1	MED25	29328	0.05966652
791773	taxon:9606	2.53458327	2.53E-05	166947	1902	ribosome production factor 2 homolog	gene	biological_process-&-1&-GO:0000463-&&-maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding	G:9606:RPF2				RPF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPF2	0.39454218	0.31981982	37	4	FALSE	RPF2	RPF2	206.9189189	0	37	0	0.74423612	FALSE	0	RPF2	62316	0.06927825
791923	taxon:9606	2.50559319	1.38E-04	182869	1902	aldehyde dehydrogenase 2 family (mitochondrial)	gene	biological_process-&-1&-GO:0006068-&&-ethanol catabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0006066-&&-alcohol metabolic process-%%-GO:0006069-&&-ethanol oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0004030-&&-aldehyde dehydrogenase [NAD(P)+] activity	G:9606:ALDH2			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00340-&&-Histidine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	ALDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH2	0.39910709	0.07563025	37	4	FALSE	ALDH2	ALDH2	161.8285714	0	36	0	0.7490678	FALSE	1	ALDH2	159256	0.05171026
791948	taxon:9606	2.61336064	9.80E-05	166439	1902	ELL associated factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0015030-&&-Cajal body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0032783-&&-ELL-EAF complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EAF1				EAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EAF1	0.38264906	0.1036036	37	4	FALSE	EAF1	EAF1	104.8378378	0	37	0	0.73110656	FALSE	0	EAF1	105576	0.04232596
791960	taxon:9606	2.56798487	5.75E-05	182807	1902	solute carrier family 25 member 4	gene	biological_process-&-1&-GO:0015853-&&-adenine transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0000002-&&-mitochondrial genome maintenance-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0006810-&&-transport-%%-GO:0015867-&&-ATP transport-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0016032-&&-viral process-%%-GO:0015866-&&-ADP transport-%%-GO:0060546-&&-negative regulation of necroptotic process-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015207-&&-adenine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005471-&&-ATP:ADP antiporter activity	G:9606:SLC25A4			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05016-&&-Huntington disease-%%-hsa04218-&&-Cellular senescence-%%-hsa04217-&&-Necroptosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	SLC25A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A4	0.38941039	0.10660661	37	4	FALSE	SLC25A4	SLC25A4	173.1351351	0	37	0	0.73866919	FALSE	0	SLC25A4	97418	0.06254519
792026	taxon:9606	2.50480542	5.92E-05	182719	1902	bleomycin hydrolase	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0009636-&&-response to toxic substance-%%-GO:0043418-&&-homocysteine catabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0004180-&&-carboxypeptidase activity	G:9606:BLMH				BLMH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLMH	0.39923261	0.09411765	37	4	FALSE	BLMH	BLMH	175.9428571	0	36	0	0.7491991	FALSE	1	BLMH	95234	0.05585365
792440	taxon:9606	2.60831889	2.87E-05	165631	1902	target of EGR1, member 1 (nuclear)	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity	G:9606:TOE1				TOE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOE1	0.3833887	0.12436975	37	4	FALSE	TOE1	TOE1	159.2285714	0	36	0	0.73194685	FALSE	1	TOE1	55394	0.06300424
792704	taxon:9606	2.63667875	5.20E-05	181532	1902	desmin	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0045109-&&-intermediate filament organization-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005916-&&-fascia adherens-%%-GO:0042383-&&-sarcolemma-%%-GO:0014704-&&-intercalated disc-%%-GO:0005882-&&-intermediate filament-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:DES	DES	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	DES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DES	0.37926501	0.05855856	37	4	FALSE	DES	DES	115.1621622	0	37	0	0.72722021	FALSE	0	DES	71530	0.04910333
792707	taxon:9606	2.55018119	3.95E-05	181530	1902	DNA fragmentation factor subunit alpha	gene	biological_process-&-1&-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1900118-&&-negative regulation of execution phase of apoptosis-%%-GO:1902511-&&-negative regulation of apoptotic DNA fragmentation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005811-&&-lipid particle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DFFA			KEGG-&-1&-hsa04210-&&-Apoptosis	DFFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DFFA	0.392129	0.17647059	37	4	FALSE	DFFA	DFFA	178.9714286	0	36	0	0.74163647	FALSE	1	DFFA	66644	0.06204676
792802	taxon:9606	2.45643611	5.62E-05	181345	1902	eukaryotic translation initiation factor 5A	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045905-&&-positive regulation of translational termination-%%-GO:0008612-&&-peptidyl-lysine modification to peptidyl-hypusine-%%-GO:0006452-&&-translational frameshifting-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0045901-&&-positive regulation of translational elongation-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005642-&&-annulate lamellae-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0017070-&&-U6 snRNA binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding	G:9606:EIF5A				EIF5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF5A	0.40709384	0.17267267	37	4	FALSE	EIF5A	EIF5A	242.8918919	0	37	0	0.75726065	FALSE	0	EIF5A	112396	0.07055138
792803	taxon:9606	2.44524972	7.28E-05	181347	1902	eukaryotic translation initiation factor 4 gamma 2	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0034645-&&-cellular macromolecule biosynthetic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006413-&&-translational initiation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0008219-&&-cell death-%%-GO:0010507-&&-negative regulation of autophagy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding	G:9606:EIF4G2			KEGG-&-1&-hsa05416-&&-Viral myocarditis-%%-hsa03013-&&-RNA transport	EIF4G2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4G2	0.40895619	0.2042042	37	4	FALSE	EIF4G2	EIF4G2	229.8918919	0	37	0	0.75912505	FALSE	0	EIF4G2	122178	0.06541725
792837	taxon:9606	2.7214432	1.09E-04	181287	1902	EPH receptor B2	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0007413-&&-axonal fasciculation-%%-GO:0099557-&&-trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission-%%-GO:0001655-&&-urogenital system development-%%-GO:0048170-&&-positive regulation of long-term neuronal synaptic plasticity-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0007399-&&-nervous system development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0060996-&&-dendritic spine development-%%-GO:0016310-&&-phosphorylation-%%-GO:0021952-&&-central nervous system projection neuron axonogenesis-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0050878-&&-regulation of body fluid levels-%%-GO:0022038-&&-corpus callosum development-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0071679-&&-commissural neuron axon guidance-%%-GO:0021631-&&-optic nerve morphogenesis-%%-GO:0060021-&&-palate development-%%-GO:0007411-&&-axon guidance-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007612-&&-learning|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005005-&&-transmembrane-ephrin receptor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008046-&&-axon guidance receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding	G:9606:EPHB2			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHB2	0.36745209	0.09747899	37	4	FALSE	EPHB2	EPHB2	94.77142857	0	36	0	0.7130928	FALSE	1	EPHB2	114662	0.05293081
792848	taxon:9606	2.67575232	5.48E-05	164885	1902	nucleoporin 35	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006999-&&-nuclear pore organization-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0055085-&&-transmembrane transport-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005652-&&-nuclear lamina-%%-GO:0044613-&&-nuclear pore central transport channel-%%-GO:0044615-&&-nuclear pore nuclear basket|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0005487-&&-nucleocytoplasmic transporter activity	G:9606:NUP35			KEGG-&-1&-hsa03013-&&-RNA transport	NUP35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP35	0.37372667	0.14564565	37	4	FALSE	NUP35	NUP35	109.5675676	0	37	0	0.72070795	FALSE	0	NUP35	70652	0.05202349
792997	taxon:9606	2.48684418	5.82E-05	181027	1902	fragile X mental retardation 1	gene	biological_process-&-1&-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:2000301-&&-negative regulation of synaptic vesicle exocytosis-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:1901254-&&-positive regulation of intracellular transport of viral material-%%-GO:0008380-&&-RNA splicing-%%-GO:1902416-&&-positive regulation of mRNA binding-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0051028-&&-mRNA transport-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0044830-&&-modulation by host of viral RNA genome replication-%%-GO:1900453-&&-negative regulation of long term synaptic depression-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0045947-&&-negative regulation of translational initiation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006397-&&-mRNA processing-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0051489-&&-regulation of filopodium assembly-%%-GO:1901386-&&-negative regulation of voltage-gated calcium channel activity-%%-GO:0046928-&&-regulation of neurotransmitter secretion-%%-GO:0060964-&&-regulation of gene silencing by miRNA-%%-GO:2000766-&&-negative regulation of cytoplasmic translation-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0098908-&&-regulation of neuronal action potential-%%-GO:0098586-&&-cellular response to virus|cellular_component-&-1&-GO:0043679-&&-axon terminus-%%-GO:0042788-&&-polysomal ribosome-%%-GO:0005694-&&-chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0005730-&&-nucleolus-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0030425-&&-dendrite-%%-GO:0043005-&&-neuron projection-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0015030-&&-Cajal body-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045202-&&-synapse-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0043197-&&-dendritic spine-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0005634-&&-nucleus-%%-GO:0098794-&&-postsynapse-%%-GO:0010369-&&-chromocenter-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0005844-&&-polysome-%%-GO:0043204-&&-perikaryon-%%-GO:0016020-&&-membrane-%%-GO:0032797-&&-SMN complex-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0071598-&&-neuronal ribonucleoprotein granule-%%-GO:0097386-&&-glial cell projection-%%-GO:1990812-&&-growth cone filopodium-%%-GO:1990904-&&-ribonucleoprotein complex-%%-GO:0042995-&&-cell projection-%%-GO:0005829-&&-cytosol-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0019034-&&-viral replication complex-%%-GO:0032433-&&-filopodium tip-%%-GO:1902737-&&-dendritic filopodium|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0030371-&&-translation repressor activity-%%-GO:0033592-&&-RNA strand annealing activity-%%-GO:0043022-&&-ribosome binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0034046-&&-poly(G) binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0048027-&&-mRNA 5'-UTR binding-%%-GO:0035197-&&-siRNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:1990825-&&-sequence-specific mRNA binding	G:9606:FMR1	FMR1	TRUE	KEGG-&-1&-hsa03013-&&-RNA transport	FMR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FMR1	0.40211607	0.13613445	37	4	FALSE	FMR1	FMR1	205.2	0	36	0	0.75219264	FALSE	1	FMR1	92568	0.06290973
793114	taxon:9606	2.54167323	3.62E-05	180704	1902	GDP dissociation inhibitor 2	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0015031-&&-protein transport-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007165-&&-signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0031982-&&-vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005093-&&-Rab GDP-dissociation inhibitor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0031267-&&-small GTPase binding	G:9606:GDI2				GDI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GDI2	0.39344161	0.14714715	37	4	FALSE	GDI2	GDI2	188.8648649	0	37	0	0.74305446	FALSE	0	GDI2	81016	0.06476655
793260	taxon:9606	2.52906885	2.75E-05	180415	1902	general transcription factor IIIC subunit 2	gene	biological_process-&-1&-GO:0042797-&&-tRNA transcription from RNA polymerase III promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042791-&&-5S class rRNA transcription from RNA polymerase III type 1 promoter|cellular_component-&-1&-GO:0000127-&&-transcription factor TFIIIC complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding	G:9606:GTF3C2				GTF3C2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF3C2	0.39540244	0.12162162	37	4	FALSE	GTF3C2	GTF3C2	213.6486487	0	37	0	0.74515519	FALSE	0	GTF3C2	76390	0.07088424
793277	taxon:9606	2.50433276	7.11E-05	180386	1902	histone cluster 1 H1 family member d	gene	biological_process-&-1&-GO:0016584-&&-nucleosome positioning-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0080182-&&-histone H3-K4 trimethylation|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:HIST1H1D				HIST1H1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1D	0.39930796	0.13063063	37	4	FALSE	HIST1H1D	HIST1H1D	256.8108108	0	37	0	0.74927787	FALSE	0	HIST1H1D	130870	0.08156202
793325	taxon:9606	2.56357334	1.05E-04	180313	1902	human immunodeficiency virus type I enhancer binding protein 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001206-&&-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:HIVEP1				HIVEP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIVEP1	0.39008051	0.05705706	37	4	FALSE	HIVEP1	HIVEP1	137.2162162	0	37	0	0.73940444	FALSE	0	HIVEP1	123368	0.04956422
793350	taxon:9606	2.60595557	1.36E-04	180255	1902	heme oxygenase 2	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0042167-&&-heme catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0006788-&&-heme oxidation-%%-GO:0055072-&&-iron ion homeostasis|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004392-&&-heme oxygenase (decyclizing) activity-%%-GO:0020037-&&-heme binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:HMOX2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa04978-&&-Mineral absorption	HMOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMOX2	0.3837364	0.04504505	37	4	FALSE	HMOX2	HMOX2	113.0540541	0	37	0	0.73234074	FALSE	0	HMOX2	146318	0.04520766
787320	taxon:9606	2.52449976	2.98E-05	179668	1902	keratin 6A	gene	biological_process-&-1&-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT6A				KRT6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT6A	0.39611808	0.14444444	36	4	FALSE	KRT6A	KRT6A	230.4444444	0	36	0	0.74591671	FALSE	0	KRT6A	81304	0.07608616
787332	taxon:9606	2.50669608	3.81E-05	179653	1902	keratin 19	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0016032-&&-viral process-%%-GO:0060706-&&-cell differentiation involved in embryonic placenta development-%%-GO:0045214-&&-sarcomere organization-%%-GO:0043627-&&-response to estrogen|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:1990357-&&-terminal web-%%-GO:0043034-&&-costamere-%%-GO:0005882-&&-intermediate filament-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding	G:9606:KRT19			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT19	0.39893149	0.13368984	36	4	FALSE	KRT19	KRT19	225.6176471	0	35	0	0.74888399	FALSE	1	KRT19	79928	0.07209595
787450	taxon:9606	2.47707578	2.63E-05	179411	1902	myocyte enhancer factor 2D	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0007517-&&-muscle organ development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007399-&&-nervous system development-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0007512-&&-adult heart development-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0001958-&&-endochondral ossification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:MEF2D			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MEF2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEF2D	0.40370182	0.18894831	36	4	FALSE	MEF2D	MEF2D	220	0	35	0	0.7538207	FALSE	1	MEF2D	69114	0.06612564
787537	taxon:9606	2.53143217	3.92E-05	179224	1902	protein phosphatase 1 regulatory subunit 8	gene	biological_process-&-1&-GO:0090501-&&-RNA phosphodiester bond hydrolysis-%%-GO:0008283-&&-cell proliferation-%%-GO:0035308-&&-negative regulation of protein dephosphorylation-%%-GO:0008380-&&-RNA splicing-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006397-&&-mRNA processing-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008995-&&-ribonuclease E activity-%%-GO:0003677-&&-DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0004865-&&-protein serine/threonine phosphatase inhibitor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:PPP1R8				PPP1R8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R8	0.3950333	0.09206349	36	4	FALSE	PPP1R8	PPP1R8	174.6666667	0	36	0	0.7447613	FALSE	0	PPP1R8	79504	0.05878335
787588	taxon:9606	2.65101623	5.01E-05	179139	1902	NIMA related kinase 2	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0051299-&&-centrosome separation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0001824-&&-blastocyst development-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0046602-&&-regulation of mitotic centrosome separation-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:1903126-&&-negative regulation of centriole-centriole cohesion-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0051225-&&-spindle assembly|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0030496-&&-midbody-%%-GO:0000776-&&-kinetochore-%%-GO:0005874-&&-microtubule-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0000922-&&-spindle pole-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:NEK2				NEK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK2	0.37721384	0.11942959	36	4	FALSE	NEK2	NEK2	124.5294118	0	35	0	0.72483063	FALSE	1	NEK2	65702	0.05507216
787726	taxon:9606	2.49818812	4.54E-05	178870	1902	DNA polymerase alpha 1, catalytic subunit	gene	biological_process-&-1&-GO:0006270-&&-DNA replication initiation-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:0006260-&&-DNA replication-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0006273-&&-lagging strand elongation-%%-GO:0008283-&&-cell proliferation-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006281-&&-DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0016032-&&-viral process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006272-&&-leading strand elongation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006269-&&-DNA replication, synthesis of RNA primer|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005658-&&-alpha DNA polymerase:primase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005730-&&-nucleolus-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003896-&&-DNA primase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001882-&&-nucleoside binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008408-&&-3'-5' exonuclease activity	G:9606:POLA1			KEGG-&-1&-hsa03030-&&-DNA replication	POLA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLA1	0.40029011	0.22857143	36	4	FALSE	POLA1	POLA1	226.9722222	0	36	0	0.75030198	FALSE	0	POLA1	80610	0.07058061
787738	taxon:9606	2.64502915	3.39E-05	178853	1902	RNA polymerase II subunit J	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030275-&&-LRR domain binding-%%-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity	G:9606:POLR2J			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2J	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2J	0.37806767	0.2968254	36	4	FALSE	POLR2J	POLR2J	121.8888889	0	36	0	0.72582848	FALSE	0	POLR2J	55054	0.0532013
787749	taxon:9606	2.56688199	3.01E-04	178847	1902	paraoxonase 2	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0009636-&&-response to toxic substance-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:0019439-&&-aromatic compound catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0102007-&&-acyl-L-homoserine-lactone lactonohydrolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004064-&&-arylesterase activity	G:9606:PON2	PON2	TRUE		PON2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PON2	0.38957771	0.04444444	36	4	FALSE	PON2	PON2	134.1388889	0	36	0	0.738853	FALSE	0	PON2	232054	0.04867176
787999	taxon:9606	2.65968174	7.29E-05	178434	1902	pyruvate dehydrogenase kinase 1	gene	biological_process-&-1&-GO:0097411-&&-hypoxia-inducible factor-1alpha signaling pathway-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0008283-&&-cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006006-&&-glucose metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005967-&&-mitochondrial pyruvate dehydrogenase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004740-&&-pyruvate dehydrogenase (acetyl-transferring) kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PDK1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04066-&&-HIF-1 signaling pathway	PDK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDK1	0.37598484	0.057041	36	4	FALSE	PDK1	PDK1	95.91176471	0	35	0	0.72338638	FALSE	1	PDK1	79664	0.04366019
788006	taxon:9606	2.75752324	5.28E-05	178415	1902	peptidase D	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0102009-&&-proline dipeptidase activity-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0004181-&&-metallocarboxypeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:PEPD	PEPD	TRUE		PEPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEPD	0.36264427	0.18716578	36	4	FALSE	PEPD	PEPD	79.64705882	0	35	0	0.70707946	FALSE	1	PEPD	59640	0.04909823
788112	taxon:9606	2.53363794	8.45E-05	178219	1902	protein tyrosine phosphatase, non-receptor type 2	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0042527-&&-negative regulation of tyrosine phosphorylation of Stat6 protein-%%-GO:0060336-&&-negative regulation of interferon-gamma-mediated signaling pathway-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:1903899-&&-positive regulation of PERK-mediated unfolded protein response-%%-GO:0070104-&&-negative regulation of interleukin-6-mediated signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050922-&&-negative regulation of chemotaxis-%%-GO:1902212-&&-negative regulation of prolactin signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1902215-&&-negative regulation of interleukin-4-mediated signaling pathway-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0045650-&&-negative regulation of macrophage differentiation-%%-GO:1902206-&&-negative regulation of interleukin-2-mediated signaling pathway-%%-GO:1902227-&&-negative regulation of macrophage colony-stimulating factor signaling pathway-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0030217-&&-T cell differentiation-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0042512-&&-negative regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0030183-&&-B cell differentiation-%%-GO:1902233-&&-negative regulation of positive thymic T cell selection-%%-GO:0042524-&&-negative regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0045722-&&-positive regulation of gluconeogenesis-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:1902202-&&-regulation of hepatocyte growth factor receptor signaling pathway-%%-GO:0060339-&&-negative regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097677-&&-STAT family protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0005178-&&-integrin binding	G:9606:PTPN2			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway	PTPN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN2	0.39468938	0.13809524	36	4	FALSE	PTPN2	PTPN2	162.6388889	0	36	0	0.74439368	FALSE	0	PTPN2	115272	0.05494495
788321	taxon:9606	2.56121002	5.56E-05	177888	1902	VPS52, GARP complex subunit	gene	biological_process-&-1&-GO:0007041-&&-lysosomal transport-%%-GO:0015031-&&-protein transport-%%-GO:0006896-&&-Golgi to vacuole transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0048611-&&-embryonic ectodermal digestive tract development-%%-GO:0010668-&&-ectodermal cell differentiation-%%-GO:0032456-&&-endocytic recycling|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:1990745-&&-EARP complex-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane-%%-GO:0000938-&&-GARP complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0055037-&&-recycling endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:VPS52				VPS52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS52	0.39044045	0.057041	36	4	FALSE	VPS52	VPS52	137.3823529	0	35	0	0.73979833	FALSE	1	VPS52	82342	0.04890427
788586	taxon:9606	2.77769025	2.33E-04	177392	1902	tafazzin	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0042407-&&-cristae formation-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0007507-&&-heart development-%%-GO:0006936-&&-muscle contraction-%%-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0032049-&&-cardiolipin biosynthetic process-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0030097-&&-hemopoiesis-%%-GO:0042775-&&-mitochondrial ATP synthesis coupled electron transport-%%-GO:0048738-&&-cardiac muscle tissue development|cellular_component-&-1&-GO:0031966-&&-mitochondrial membrane-%%-GO:0031224-&&-intrinsic component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008374-&&-O-acyltransferase activity-%%-GO:0003841-&&-1-acylglycerol-3-phosphate O-acyltransferase activity-%%-GO:0047184-&&-1-acylglycerophosphocholine O-acyltransferase activity	G:9606:TAZ			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism	TAZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAZ	0.36001134	0.03809524	36	4	FALSE	TAZ	TAZ	61.55555556	0	36	0	0.70371829	FALSE	0	TAZ	196716	0.04224217
788651	taxon:9606	2.54277611	8.93E-05	177248	1902	transforming growth factor beta 1 induced transcript 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009408-&&-response to heat-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0030579-&&-ubiquitin-dependent SMAD protein catabolic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0016331-&&-morphogenesis of embryonic epithelium-%%-GO:0045165-&&-cell fate commitment|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005622-&&-intracellular-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0050681-&&-androgen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0048495-&&-Roundabout binding-%%-GO:0070411-&&-I-SMAD binding	G:9606:TGFB1I1				TGFB1I1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFB1I1	0.39327096	0.12063492	36	4	FALSE	TGFB1I1	TGFB1I1	151.8611111	0	36	0	0.74287065	FALSE	0	TGFB1I1	128466	0.05214057
788957	taxon:9606	2.53426816	7.13E-05	176532	1902	RAN binding protein 3	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0046604-&&-positive regulation of mitotic centrosome separation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007051-&&-spindle organization-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070412-&&-R-SMAD binding-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RANBP3			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	RANBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP3	0.39459123	0.13809524	36	4	FALSE	RANBP3	RANBP3	156.25	0	36	0	0.74428864	FALSE	0	RANBP3	96300	0.05262517
788999	taxon:9606	2.82164802	4.09E-05	160044	1902	NADH:ubiquinone oxidoreductase core subunit S7	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0043005-&&-neuron projection-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0097060-&&-synaptic membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0002020-&&-protease binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0048038-&&-quinone binding-%%-GO:0003954-&&-NADH dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:NDUFS7			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS7	0.35440281	0.29055258	36	4	FALSE	NDUFS7	NDUFS7	81.35294118	0	35	0	0.696392	FALSE	1	NDUFS7	52968	0.0625652
789020	taxon:9606	2.66945013	1.02E-04	176361	1902	leucine zipper like transcription regulator 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009653-&&-anatomical structure morphogenesis|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:LZTR1				LZTR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LZTR1	0.37460898	0.04278075	36	4	FALSE	LZTR1	LZTR1	105.9117647	0	35	0	0.72175831	FALSE	1	LZTR1	128534	0.04942389
789122	taxon:9606	2.79155507	4.19E-05	176153	1902	kynureninase	gene	biological_process-&-1&-GO:0006569-&&-tryptophan catabolic process-%%-GO:0019442-&&-tryptophan catabolic process to acetyl-CoA-%%-GO:0034516-&&-response to vitamin B6-%%-GO:0019805-&&-quinolinate biosynthetic process-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0009435-&&-NAD biosynthetic process-%%-GO:0097053-&&-L-kynurenine catabolic process-%%-GO:0043420-&&-anthranilate metabolic process-%%-GO:0019441-&&-tryptophan catabolic process to kynurenine|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030429-&&-kynureninase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:KYNU	KYNU	TRUE	KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways	KYNU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KYNU	0.35822328	0.1047619	36	4	FALSE	KYNU	KYNU	67.38888889	0	36	0	0.70140749	FALSE	0	KYNU	46538	0.04820789
789213	taxon:9606	2.53190484	6.53E-05	175985	1902	adaptor related protein complex 3 beta 1 subunit	gene	biological_process-&-1&-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0051138-&&-positive regulation of NK T cell differentiation-%%-GO:0032438-&&-melanosome organization-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0007596-&&-blood coagulation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048007-&&-antigen processing and presentation, exogenous lipid antigen via MHC class Ib|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0030123-&&-AP-3 adaptor complex|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0030742-&&-GTP-dependent protein binding	G:9606:AP3B1			KEGG-&-1&-hsa04142-&&-Lysosome	AP3B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP3B1	0.39495955	0.11904762	36	4	FALSE	AP3B1	AP3B1	164.1388889	0	36	0	0.74468253	FALSE	0	AP3B1	106300	0.05490437
789323	taxon:9606	2.52780841	6.14E-05	175738	1902	golgi brefeldin A resistant guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0061162-&&-establishment of monopolar cell polarity-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0048205-&&-COPI coating of Golgi vesicle-%%-GO:0070973-&&-protein localization to endoplasmic reticulum exit site-%%-GO:0007030-&&-Golgi organization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0097111-&&-endoplasmic reticulum-Golgi intermediate compartment organization-%%-GO:0006895-&&-Golgi to endosome transport-%%-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0002263-&&-cell activation involved in immune response-%%-GO:1903420-&&-protein localization to endoplasmic reticulum tubular network-%%-GO:0016032-&&-viral process-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0090166-&&-Golgi disassembly-%%-GO:1903409-&&-reactive oxygen species biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005795-&&-Golgi stack-%%-GO:0005829-&&-cytosol-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0005739-&&-mitochondrion-%%-GO:0031252-&&-cell leading edge-%%-GO:0016020-&&-membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005811-&&-lipid particle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding	G:9606:GBF1			KEGG-&-1&-hsa04144-&&-Endocytosis	GBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBF1	0.3955996	0.10793651	36	4	FALSE	GBF1	GBF1	172.9722222	0	36	0	0.74536526	FALSE	0	GBF1	103742	0.05742894
789433	taxon:9606	2.66755948	3.35E-04	175490	1902	translocase of outer mitochondrial membrane 20	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0016031-&&-tRNA import into mitochondrion-%%-GO:0070096-&&-mitochondrial outer membrane translocase complex assembly-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0016236-&&-macroautophagy-%%-GO:0030150-&&-protein import into mitochondrial matrix|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030943-&&-mitochondrion targeting sequence binding-%%-GO:0015450-&&-P-P-bond-hydrolysis-driven protein transmembrane transporter activity-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0015266-&&-protein channel activity	G:9606:TOMM20				TOMM20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM20	0.37487449	0.07619048	36	4	FALSE	TOMM20	TOMM20	103.4166667	0	36	0	0.72207342	FALSE	0	TOMM20	434872	0.04839298
789453	taxon:9606	2.54892075	6.01E-05	175439	1902	BCL2 associated athanogene 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0070997-&&-neuron death-%%-GO:0090083-&&-regulation of inclusion body assembly-%%-GO:0051438-&&-regulation of ubiquitin-protein transferase activity-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0051444-&&-negative regulation of ubiquitin-protein transferase activity-%%-GO:0007030-&&-Golgi organization-%%-GO:0061084-&&-negative regulation of protein refolding-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0031397-&&-negative regulation of protein ubiquitination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0016234-&&-inclusion body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0000774-&&-adenyl-nucleotide exchange factor activity-%%-GO:0051087-&&-chaperone binding	G:9606:BAG5				BAG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAG5	0.39232291	0.08912656	36	4	FALSE	BAG5	BAG5	165.7058824	0	35	0	0.74184654	FALSE	1	BAG5	88988	0.05721777
789511	taxon:9606	2.42681582	6.79E-05	175307	1902	ubiquitin protein ligase E3C	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000502-&&-proteasome complex-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:UBE3C			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE3C	0.41206259	0.12655971	36	4	FALSE	UBE3C	UBE3C	222.8823529	0	35	0	0.76219736	FALSE	1	UBE3C	112022	0.0612826
789562	taxon:9606	2.79265795	5.14E-05	175174	1902	zinc finger and BTB domain containing 24	gene	biological_process-&-1&-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB24				ZBTB24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB24	0.35808181	0.06984127	36	5	FALSE	ZBTB24	ZBTB24	86.05555556	0	36	0	0.70122368	FALSE	0	ZBTB24	81838	0.05977545
789565	taxon:9606	2.50386009	2.64E-05	175170	1902	GRB2 associated binding protein 2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0030316-&&-osteoclast differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity	G:9606:GAB2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia	GAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAB2	0.39938334	0.38146168	36	4	FALSE	GAB2	GAB2	214.4117647	0	35	0	0.74935665	FALSE	1	GAB2	59068	0.06795935
789579	taxon:9606	2.67118324	7.89E-05	175137	1902	POM121 transmembrane nucleoporin	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0044613-&&-nuclear pore central transport channel-%%-GO:0016021-&&-integral component of membrane-%%-GO:0044615-&&-nuclear pore nuclear basket|molecular_function-&-1&-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0017056-&&-structural constituent of nuclear pore	G:9606:POM121			KEGG-&-1&-hsa03013-&&-RNA transport	POM121	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POM121	0.37436593	0.04634581	36	4	FALSE	POM121	POM121	102.3529412	0	35	0	0.72146946	FALSE	1	POM121	85150	0.04804014
789612	taxon:9606	2.75248149	1.47E-05	175059	1902	mediator complex subunit 13	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:1904168-&&-negative regulation of thyroid hormone receptor activity-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004872-&&-receptor activity-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding	G:9606:MED13			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED13	0.36330853	0.51587302	36	4	FALSE	MED13	MED13	94.66666667	0	36	0	0.70791975	FALSE	0	MED13	26516	0.05678864
789693	taxon:9606	2.57885615	6.62E-05	174882	1902	serine/threonine kinase 25	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0051645-&&-Golgi localization-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0036481-&&-intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:0090168-&&-Golgi reassembly|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:STK25				STK25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK25	0.38776882	0.1942959	36	4	FALSE	STK25	STK25	142.9705882	0	35	0	0.73685731	FALSE	1	STK25	87428	0.05286933
789796	taxon:9606	2.60485269	3.17E-05	174644	1902	mitochondrial ribosomal protein S31	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS31				MRPS31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS31	0.38389887	0.28571429	36	4	FALSE	MRPS31	MRPS31	141.8333333	0	36	0	0.73252455	FALSE	0	MRPS31	54936	0.05593908
789904	taxon:9606	2.49314637	7.60E-05	174395	1902	myosin light chain 12A	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0070527-&&-platelet aggregation-%%-GO:0048013-&&-ephrin receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016459-&&-myosin complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MYL12A			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYL12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL12A	0.4010996	0.11269841	36	4	FALSE	MYL12A	MYL12A	229.4166667	0	36	0	0.75114227	FALSE	0	MYL12A	139840	0.07131502
789952	taxon:9606	2.52812352	3.41E-05	174256	1902	serologically defined colon cancer antigen 3	gene	biological_process-&-1&-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle-%%-GO:0032465-&&-regulation of cytokinesis|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0030904-&&-retromer complex-%%-GO:0005769-&&-early endosome-%%-GO:0005768-&&-endosome-%%-GO:0055037-&&-recycling endosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SDCCAG3				SDCCAG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDCCAG3	0.39555029	0.2031746	36	4	FALSE	SDCCAG3	SDCCAG3	168.3611111	0	36	0	0.74531275	FALSE	0	SDCCAG3	74962	0.0559247
790132	taxon:9606	2.58311013	5.07E-05	173797	1902	nuclear cap binding protein subunit 2	gene	biological_process-&-1&-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1900363-&&-regulation of mRNA polyadenylation-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0031442-&&-positive regulation of mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006408-&&-snRNA export from nucleus-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0010467-&&-gene expression-%%-GO:0008380-&&-RNA splicing-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0051168-&&-nuclear export-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046833-&&-positive regulation of RNA export from nucleus-%%-GO:0008334-&&-histone mRNA metabolic process|cellular_component-&-1&-GO:0005846-&&-nuclear cap binding complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005845-&&-mRNA cap binding complex|molecular_function-&-1&-GO:0000339-&&-RNA cap binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0017069-&&-snRNA binding	G:9606:NCBP2			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03040-&&-Spliceosome-%%-hsa03015-&&-mRNA surveillance pathway	NCBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCBP2	0.38713022	0.13333333	36	4	FALSE	NCBP2	NCBP2	166.6666667	0	36	0	0.73614831	FALSE	0	NCBP2	73744	0.06162905
790134	taxon:9606	2.57743816	7.57E-05	173793	1902	kinesin associated protein 3	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0046587-&&-positive regulation of calcium-dependent cell-cell adhesion-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007017-&&-microtubule-based process-%%-GO:0007165-&&-signal transduction-%%-GO:0072383-&&-plus-end-directed vesicle transport along microtubule-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:1990075-&&-periciliary membrane compartment-%%-GO:0016939-&&-kinesin II complex-%%-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0036064-&&-ciliary basal body-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005929-&&-cilium-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0030990-&&-intraciliary transport particle-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0097542-&&-ciliary tip-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding	G:9606:KIFAP3				KIFAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIFAP3	0.38798215	0.06951872	36	4	FALSE	KIFAP3	KIFAP3	128.7647059	0	35	0	0.73709364	FALSE	1	KIFAP3	90910	0.04758586
790160	taxon:9606	2.60501024	5.63E-05	173738	1902	WD repeat and FYVE domain containing 3	gene	biological_process-&-1&-GO:0035973-&&-aggrephagy|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005730-&&-nucleolus-%%-GO:0016605-&&-PML body-%%-GO:0034274-&&-Atg12-Atg5-Atg16 complex-%%-GO:0005776-&&-autophagosome-%%-GO:0016234-&&-inclusion body-%%-GO:0005634-&&-nucleus-%%-GO:0097635-&&-extrinsic component of autophagosome membrane|molecular_function-&-1&-GO:0003831-&&-beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding	G:9606:WDFY3				WDFY3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDFY3	0.38387565	0.08888889	36	4	FALSE	WDFY3	WDFY3	126.1944444	0	36	0	0.73249829	FALSE	0	WDFY3	90226	0.05014818
790171	taxon:9606	2.67102568	2.59E-05	173716	1902	microtubule associated serine/threonine kinase 3	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:MAST3				MAST3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAST3	0.37438801	0.08095238	36	4	FALSE	MAST3	MAST3	124.9166667	0	36	0	0.72149572	FALSE	0	MAST3	44042	0.05905408
790228	taxon:9606	2.49314637	7.91E-05	173582	1902	sec1 family domain containing 1	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0060628-&&-regulation of ER to Golgi vesicle-mediated transport-%%-GO:0009636-&&-response to toxic substance-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0051223-&&-regulation of protein transport-%%-GO:1901998-&&-toxin transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006909-&&-phagocytosis|cellular_component-&-1&-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0005829-&&-cytosol-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0032580-&&-Golgi cisterna membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:SCFD1				SCFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCFD1	0.4010996	0.12698413	36	4	FALSE	SCFD1	SCFD1	190.1944444	0	36	0	0.75114227	FALSE	0	SCFD1	126178	0.05886755
790230	taxon:9606	2.69938554	2.65E-05	173572	1902	MGA, MAX dimerization protein	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:MGA				MGA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGA	0.37045468	0.24126984	36	4	FALSE	MGA	MGA	208.4722222	0	36	0	0.71676908	FALSE	0	MGA	74608	0.10295894
790240	taxon:9606	2.53631637	6.04E-05	173541	1902	non-SMC condensin II complex subunit D3	gene	biological_process-&-1&-GO:0010032-&&-meiotic chromosome condensation-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0051304-&&-chromosome separation-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0000799-&&-nuclear condensin complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:NCAPD3				NCAPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPD3	0.39427258	0.11587302	36	4	FALSE	NCAPD3	NCAPD3	178.1666667	0	36	0	0.74394727	FALSE	0	NCAPD3	104120	0.05984916
790364	taxon:9606	2.75200882	2.68E-05	173215	1902	calcineurin binding protein 1	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006336-&&-DNA replication-independent nucleosome assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0031491-&&-nucleosome binding	G:9606:CABIN1				CABIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CABIN1	0.36337093	0.23529412	36	4	FALSE	CABIN1	CABIN1	194.4411765	0	35	0	0.70799853	FALSE	1	CABIN1	61818	0.11464515
790379	taxon:9606	2.67134079	1.05E-04	173175	1902	cyclin D1 binding protein 1	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCNDBP1				CCNDBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNDBP1	0.37434385	0.03174603	36	4	FALSE	CCNDBP1	CCNDBP1	103	0	36	0	0.7214432	FALSE	0	CCNDBP1	106942	0.04854203
790505	taxon:9606	2.47392469	3.32E-05	172662	1902	F-box and WD repeat domain containing 8	gene	biological_process-&-1&-GO:0007030-&&-Golgi organization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0060712-&&-spongiotrophoblast layer development-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0031467-&&-Cul7-RING ubiquitin ligase complex-%%-GO:1990393-&&-3M complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXW8			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	FBXW8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW8	0.40421602	0.23492063	36	4	FALSE	FBXW8	FBXW8	237.2777778	0	36	0	0.75434589	FALSE	0	FBXW8	66470	0.07077864
790746	taxon:9606	2.72869072	4.03E-05	171337	1902	insulin induced gene 2	gene	biological_process-&-1&-GO:0032933-&&-SREBP signaling pathway-%%-GO:0070542-&&-response to fatty acid-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0060021-&&-palate development-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0010894-&&-negative regulation of steroid biosynthetic process-%%-GO:0032868-&&-response to insulin-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0060363-&&-cranial suture morphogenesis|cellular_component-&-1&-GO:0032937-&&-SREBP-SCAP-Insig complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:INSIG2	INSIG2	TRUE		INSIG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSIG2	0.36647612	0.25396825	36	4	FALSE	INSIG2	INSIG2	119.6944444	0	36	0	0.71188488	FALSE	0	INSIG2	57228	0.06770048
790749	taxon:9606	2.47613046	3.89E-05	171335	1902	dynein cytoplasmic 1 light intermediate chain 1	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0090267-&&-positive regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0016032-&&-viral process-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0000922-&&-spindle pole-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019003-&&-GDP binding-%%-GO:0045504-&&-dynein heavy chain binding	G:9606:DYNC1LI1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04145-&&-Phagosome	DYNC1LI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC1LI1	0.40385594	0.15079365	36	4	FALSE	DYNC1LI1	DYNC1LI1	214.6111111	0	36	0	0.75397826	FALSE	0	DYNC1LI1	83122	0.06429332
790882	taxon:9606	2.65337955	6.20E-05	170787	1902	geminin, DNA replication inhibitor	gene	biological_process-&-1&-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007049-&&-cell cycle-%%-GO:0045786-&&-negative regulation of cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:GMNN				GMNN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMNN	0.37687786	0.07664884	36	4	FALSE	GMNN	GMNN	125.4117647	0	35	0	0.72443674	FALSE	1	GMNN	79718	0.05589287
790983	taxon:9606	2.72506696	3.37E-06	154119	1902	eukaryotic translation initiation factor 3 subunit C-like	gene	biological_process-&-1&-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005852-&&-eukaryotic translation initiation factor 3 complex|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0031369-&&-translation initiation factor binding	G:9606:EIF3CL			KEGG-&-1&-hsa03013-&&-RNA transport	EIF3CL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF3CL	0.36696346	0.53015873	36	4	FALSE	EIF3CL	EIF3CL	162.4722222	0	36	0	0.71248884	FALSE	0	EIF3CL	12208	0.08854072
790996	taxon:9606	2.694974	1.21E-05	170461	1902	male-specific lethal 2 homolog (Drosophila)	gene	biological_process-&-1&-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0072487-&&-MSL complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0016874-&&-ligase activity	G:9606:MSL2				MSL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSL2	0.37106109	0.2047619	36	4	FALSE	MSL2	MSL2	188.4166667	0	36	0	0.71750433	FALSE	0	MSL2	38286	0.09336802
791020	taxon:9606	2.56971798	3.88E-05	170358	1902	BCAS3, microtubule associated cell migration factor	gene	biological_process-&-1&-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0001525-&&-angiogenesis-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0007030-&&-Golgi organization-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035148-&&-tube formation-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0031023-&&-microtubule organizing center organization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042594-&&-response to starvation|cellular_component-&-1&-GO:0071944-&&-cell periphery-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0031252-&&-cell leading edge-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0042393-&&-histone binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0010698-&&-acetyltransferase activator activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0035257-&&-nuclear hormone receptor binding	G:9606:BCAS3				BCAS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAS3	0.38914776	0.18412698	36	4	FALSE	BCAS3	BCAS3	234.4166667	0	36	0	0.73838034	FALSE	0	BCAS3	106216	0.08510853
791184	taxon:9606	2.4808571	8.08E-05	169798	1902	enabled homolog (Drosophila)	gene	biological_process-&-1&-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0045202-&&-synapse-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030175-&&-filopodium|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:ENAH			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04810-&&-Regulation of actin cytoskeleton	ENAH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENAH	0.4030865	0.13012478	36	4	FALSE	ENAH	ENAH	198.8235294	0	35	0	0.75319048	FALSE	1	ENAH	117672	0.05974292
791252	taxon:9606	2.69938554	5.96E-05	169528	1902	diablo IAP-binding mitochondrial protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0051402-&&-neuron apoptotic process|cellular_component-&-1&-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0035631-&&-CD40 receptor complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DIABLO			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis	DIABLO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIABLO	0.37045468	0.11229947	36	4	FALSE	DIABLO	DIABLO	101.7647059	0	35	0	0.71676908	FALSE	1	DIABLO	72222	0.05184574
791457	taxon:9606	2.46699228	5.54E-05	168568	1902	DEAD-box helicase 54	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005102-&&-receptor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0030331-&&-estrogen receptor binding	G:9606:DDX54				DDX54	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX54	0.4053519	0.13809524	36	4	FALSE	DDX54	DDX54	226.9166667	0	36	0	0.75550129	FALSE	0	DDX54	114624	0.06713031
791512	taxon:9606	2.62171104	5.67E-05	168335	1902	AKT interacting protein	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0006915-&&-apoptotic process-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0007032-&&-endosome organization-%%-GO:0015031-&&-protein transport-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007040-&&-lysosome organization-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070695-&&-FHF complex-%%-GO:0030897-&&-HOPS complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:AKTIP				AKTIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKTIP	0.38143029	0.04444444	36	4	FALSE	AKTIP	AKTIP	108.5	0	36	0	0.72971483	FALSE	0	AKTIP	73894	0.04445585
791558	taxon:9606	2.58799433	2.37E-05	168051	1902	Sin3A associated protein 130	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0070822-&&-Sin3-type complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:SAP130				SAP130	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAP130	0.38639961	0.21269841	36	4	FALSE	SAP130	SAP130	186.0833333	0	36	0	0.73533428	FALSE	0	SAP130	56914	0.07006696
791713	taxon:9606	2.63447298	4.05E-05	167225	1902	ring finger protein 146	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0072572-&&-poly-ADP-D-ribose binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:RNF146				RNF146	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF146	0.37958256	0.09269162	36	4	FALSE	RNF146	RNF146	144.2352941	0	35	0	0.72758784	FALSE	1	RNF146	65978	0.0615373
791798	taxon:9606	2.55522294	5.63E-05	166822	1902	SAP domain containing ribonucleoprotein	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006417-&&-regulation of translation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0000346-&&-transcription export complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:SARNP				SARNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SARNP	0.39135528	0.1047619	36	4	FALSE	SARNP	SARNP	167.8333333	0	36	0	0.74079618	FALSE	0	SARNP	93900	0.05915021
791803	taxon:9606	2.69008981	2.29E-05	166788	1902	DOT1 like histone lysine methyltransferase	gene	biological_process-&-1&-GO:0006281-&&-DNA repair-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032200-&&-telomere organization-%%-GO:0034729-&&-histone H3-K79 methylation-%%-GO:0046425-&&-regulation of JAK-STAT cascade-%%-GO:0006348-&&-chromatin silencing at telomere-%%-GO:2000677-&&-regulation of transcription regulatory region DNA binding-%%-GO:0000077-&&-DNA damage checkpoint|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042054-&&-histone methyltransferase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031151-&&-histone methyltransferase activity (H3-K79 specific)	G:9606:DOT1L			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa00310-&&-Lysine degradation	DOT1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOT1L	0.3717348	0.09047619	36	5	FALSE	DOT1L	DOT1L	123.6388889	0	36	0	0.71831837	FALSE	0	DOT1L	43102	0.0613679
791836	taxon:9606	2.73546557	1.48E-04	166614	1902	transmembrane protein 25	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TMEM25				TMEM25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM25	0.36556848	0.02063492	36	4	FALSE	TMEM25	TMEM25	64.11111111	0	36	0	0.71075574	FALSE	0	TMEM25	119612	0.03706947
791914	taxon:9606	2.53221995	2.65E-05	182881	1902	adenylate kinase 2	gene	biological_process-&-1&-GO:0046939-&&-nucleotide phosphorylation-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0006172-&&-ADP biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0097226-&&-sperm mitochondrial sheath-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004017-&&-adenylate kinase activity	G:9606:AK2			KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	AK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AK2	0.3949104	0.13174603	36	4	FALSE	AK2	AK2	196.75	0	36	0	0.74463001	FALSE	0	AK2	62936	0.06591637
791964	taxon:9606	2.52071845	8.38E-05	182796	1902	annexin A6	gene	biological_process-&-1&-GO:0034220-&&-ion transmembrane transport-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0051560-&&-mitochondrial calcium ion homeostasis-%%-GO:0006816-&&-calcium ion transport-%%-GO:0006937-&&-regulation of muscle contraction|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0008289-&&-lipid binding	G:9606:ANXA6				ANXA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA6	0.39671229	0.08730159	36	4	FALSE	ANXA6	ANXA6	171.3611111	0	36	0	0.74654693	FALSE	0	ANXA6	130424	0.05639731
792058	taxon:9606	2.48621396	5.12E-05	182676	1902	basic transcription factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0015031-&&-protein transport-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:BTF3				BTF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTF3	0.402218	0.1031746	36	4	FALSE	BTF3	BTF3	195.3611111	0	36	0	0.75229767	FALSE	0	BTF3	96328	0.05979962
792123	taxon:9606	2.55412006	2.16E-05	182566	1902	mitogen-activated protein kinase kinase kinase 8	gene	biological_process-&-1&-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0031295-&&-T cell costimulation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007049-&&-cell cycle-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:MAP3K8			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	MAP3K8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K8	0.39152427	0.26916221	36	4	FALSE	MAP3K8	MAP3K8	183.2941177	0	35	0	0.74097999	FALSE	1	MAP3K8	44864	0.06451746
792330	taxon:9606	2.64061761	4.25E-05	165835	1902	protein kinase C delta binding protein	gene	biological_process-&-1&-GO:1901003-&&-negative regulation of fermentation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding	G:9606:PRKCDBP				PRKCDBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCDBP	0.37869928	0.17777778	36	4	FALSE	PRKCDBP	PRKCDBP	133.8055556	0	36	0	0.72656373	FALSE	0	PRKCDBP	64396	0.05761317
792359	taxon:9606	2.63431542	4.71E-05	182163	1902	CDC28 protein kinase regulatory subunit 1B	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0044772-&&-mitotic cell cycle phase transition-%%-GO:0008283-&&-cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0061575-&&-cyclin-dependent protein serine/threonine kinase activator activity-%%-GO:0043130-&&-ubiquitin binding	G:9606:CKS1B			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	CKS1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKS1B	0.37960526	0.22816399	36	4	FALSE	CKS1B	CKS1B	148.1764706	0	35	0	0.7276141	FALSE	1	CKS1B	67330	0.06265714
792614	taxon:9606	2.73262959	3.09E-05	181719	1902	E2F transcription factor 3	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007049-&&-cell cycle-%%-GO:0070345-&&-negative regulation of fat cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding	G:9606:E2F3			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05160-&&-Hepatitis C-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	E2F3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F3	0.36594788	0.10793651	36	5	FALSE	E2F3	E2F3	101.5	0	36	0	0.7112284	FALSE	0	E2F3	48498	0.05704142
792719	taxon:9606	2.72270364	1.16E-04	181506	1902	deoxyhypusine synthase	gene	biological_process-&-1&-GO:0008216-&&-spermidine metabolic process-%%-GO:0046203-&&-spermidine catabolic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0008612-&&-peptidyl-lysine modification to peptidyl-hypusine-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006412-&&-translation-%%-GO:0051289-&&-protein homotetramerization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0034038-&&-deoxyhypusine synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:DHPS				DHPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHPS	0.36728199	0.06773619	36	4	FALSE	DHPS	DHPS	87.17647059	0	35	0	0.71288273	FALSE	1	DHPS	125302	0.04745697
792773	taxon:9606	2.54403655	5.58E-05	181392	1902	dihydropyrimidinase like 2	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0006897-&&-endocytosis-%%-GO:0007399-&&-nervous system development-%%-GO:0007420-&&-brain development-%%-GO:0030516-&&-regulation of axon extension|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004157-&&-dihydropyrimidinase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:DPYSL2			KEGG-&-1&-hsa04360-&&-Axon guidance	DPYSL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPYSL2	0.39307611	0.08199643	36	4	FALSE	DPYSL2	DPYSL2	172.7352941	0	35	0	0.74266057	FALSE	1	DPYSL2	92782	0.05910566
792849	taxon:9606	2.52339688	6.03E-05	181269	1902	ERCC excision repair 2, TFIIH core complex helicase subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030282-&&-bone mineralization-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0021510-&&-spinal cord development-%%-GO:0006915-&&-apoptotic process-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0008283-&&-cell proliferation-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0060218-&&-hematopoietic stem cell differentiation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0016032-&&-viral process-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0032289-&&-central nervous system myelin formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048568-&&-embryonic organ development-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007568-&&-aging-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0009791-&&-post-embryonic development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035315-&&-hair cell differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0009650-&&-UV protection-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0000439-&&-core TFIIH complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0071817-&&-MMXD complex-%%-GO:0005675-&&-holo TFIIH complex-%%-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0043139-&&-5'-3' DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:ERCC2			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa03420-&&-Nucleotide excision repair	ERCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC2	0.39629121	0.15508021	36	4	FALSE	ERCC2	ERCC2	164.5	0	35	0	0.74610052	FALSE	1	ERCC2	92022	0.05347681
792986	taxon:9606	2.68756893	2.55E-04	181037	1902	fms related tyrosine kinase 1	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0038084-&&-vascular endothelial growth factor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0036323-&&-vascular endothelial growth factor receptor-1 signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0016477-&&-cell migration-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0048598-&&-embryonic morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0010863-&&-positive regulation of phospholipase C activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0036332-&&-placental growth factor-activated receptor activity-%%-GO:0036327-&&-VEGF-B-activated receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0036326-&&-VEGF-A-activated receptor activity	G:9606:FLT1	FLT1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	FLT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLT1	0.37208348	0.22459893	36	4	FALSE	FLT1	FLT1	129.4705882	0	35	0	0.71873851	FALSE	1	FLT1	357764	0.06430262
793067	taxon:9606	2.5389948	3.32E-05	180809	1902	general transcription factor IIE subunit 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005673-&&-transcription factor TFIIE complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:GTF2E2			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis	GTF2E2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2E2	0.39385666	0.14795009	36	5	FALSE	GTF2E2	GTF2E2	157.4117647	0	35	0	0.74350087	FALSE	1	GTF2E2	65552	0.05308804
793069	taxon:9606	2.70237908	5.02E-05	164427	1902	ring finger protein 32	gene	cellular_component-&-1&-GO:0016235-&&-aggresome-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:RNF32				RNF32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF32	0.37004431	0.23707665	36	4	FALSE	RNF32	RNF32	83.64705882	0	35	0	0.71627015	FALSE	1	RNF32	53970	0.0430564
793207	taxon:9606	2.45690878	9.06E-05	180525	1902	hydroxysteroid 17-beta dehydrogenase 4	gene	biological_process-&-1&-GO:0033540-&&-fatty acid beta-oxidation using acyl-CoA oxidase-%%-GO:0036111-&&-very long-chain fatty-acyl-CoA metabolic process-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0008210-&&-estrogen metabolic process-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0036112-&&-medium-chain fatty-acyl-CoA metabolic process-%%-GO:0000038-&&-very long-chain fatty acid metabolic process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0036109-&&-alpha-linolenic acid metabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0016020-&&-membrane-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0016508-&&-long-chain-enoyl-CoA hydratase activity-%%-GO:0033989-&&-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity-%%-GO:0044594-&&-17-beta-hydroxysteroid dehydrogenase (NAD+) activity-%%-GO:0016853-&&-isomerase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity-%%-GO:0005102-&&-receptor binding	G:9606:HSD17B4			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids	HSD17B4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B4	0.40701552	0.11051693	36	4	FALSE	HSD17B4	HSD17B4	222.7647059	0	35	0	0.75718187	FALSE	1	HSD17B4	133568	0.06451668
793335	taxon:9606	2.85694029	1.43E-04	180299	1902	major histocompatibility complex, class II, DP alpha 1	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0031295-&&-T cell costimulation-%%-GO:0006955-&&-immune response-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0042102-&&-positive regulation of T cell proliferation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0042613-&&-MHC class II protein complex-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0032395-&&-MHC class II receptor activity-%%-GO:0042605-&&-peptide antigen binding	G:9606:HLA-DPA1			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05323-&&-Rheumatoid arthritis	HLA-DPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-DPA1	0.35002482	0.01587302	36	4	FALSE	HLA-DPA1	HLA-DPA1	38.55555556	0	36	0	0.69050995	FALSE	0	HLA-DPA1	161446	0.03775998
787059	taxon:9606	2.75311171	6.39E-05	180151	1902	interferon induced protein with tetratricopeptide repeats 1	gene	biological_process-&-1&-GO:0019060-&&-intracellular transport of viral protein in host cell-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0009615-&&-response to virus-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0071357-&&-cellular response to type I interferon-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0050689-&&-negative regulation of defense response to virus by host-%%-GO:0051607-&&-defense response to virus-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0051097-&&-negative regulation of helicase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0043657-&&-host cell|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:IFIT1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C	IFIT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFIT1	0.36322536	0.0789916	35	4	FALSE	IFIT1	IFIT1	100.2	0	35	0	0.70781472	FALSE	0	IFIT1	112362	0.06016847
787172	taxon:9606	2.46636206	8.73E-05	179924	1902	lysozyme	gene	biological_process-&-1&-GO:0042742-&&-defense response to bacterium-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0001895-&&-retina homeostasis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019835-&&-cytolysis-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0035580-&&-specific granule lumen|molecular_function-&-1&-GO:0003796-&&-lysozyme activity-%%-GO:0042802-&&-identical protein binding	G:9606:LYZ	LYZ	TRUE	KEGG-&-1&-hsa04970-&&-Salivary secretion	LYZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYZ	0.40545547	0.09090909	35	4	FALSE	LYZ	LYZ	230.1212121	0	34	0	0.75560632	FALSE	1	LYZ	119408	0.06822454
787242	taxon:9606	2.53458327	5.92E-05	179808	1902	interferon regulatory factor 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0032494-&&-response to peptidoglycan|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000975-&&-regulatory region DNA binding-%%-GO:0005515-&&-protein binding	G:9606:IRF5			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway	IRF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF5	0.39454218	0.16287879	35	4	FALSE	IRF5	IRF5	193.0606061	0	34	0	0.74423612	FALSE	1	IRF5	85782	0.06521606
787326	taxon:9606	2.52008823	1.28E-05	179660	1902	keratin 14	gene	biological_process-&-1&-GO:0007568-&&-aging-%%-GO:0008544-&&-epidermis development-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0045110-&&-intermediate filament bundle assembly-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0042633-&&-hair cycle-%%-GO:0010043-&&-response to zinc ion|cellular_component-&-1&-GO:0045178-&&-basal part of cell-%%-GO:0071944-&&-cell periphery-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0045095-&&-keratin filament-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:1990254-&&-keratin filament binding-%%-GO:0005515-&&-protein binding	G:9606:KRT14			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT14	0.3968115	0.26554622	35	4	FALSE	KRT14	KRT14	280.7142857	0	35	0	0.74665196	FALSE	0	KRT14	44588	0.09211871
787331	taxon:9606	2.50968962	2.99E-05	163269	1902	DEAH-box helicase 36	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0001503-&&-ossification-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0090669-&&-telomerase RNA stabilization-%%-GO:0032206-&&-positive regulation of telomere maintenance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006396-&&-RNA processing-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0002151-&&-G-quadruplex RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0051880-&&-G-quadruplex DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:DHX36			KEGG-&-1&-hsa03018-&&-RNA degradation	DHX36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX36	0.39845565	0.11932773	35	4	FALSE	DHX36	DHX36	248.8	0	35	0	0.74838506	FALSE	0	DHX36	83650	0.07949198
787441	taxon:9606	2.44493461	1.15E-04	179425	1902	malate dehydrogenase 1	gene	biological_process-&-1&-GO:0006108-&&-malate metabolic process-%%-GO:0006734-&&-NADH metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006107-&&-oxaloacetate metabolic process-%%-GO:0006099-&&-tricarboxylic acid cycle|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0004470-&&-malic enzyme activity-%%-GO:0051287-&&-NAD binding-%%-GO:0030060-&&-L-malate dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0047860-&&-diiodophenylpyruvate reductase activity	G:9606:MDH1			KEGG-&-1&-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	MDH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDH1	0.40900889	0.125	35	4	FALSE	MDH1	MDH1	205.4242424	0	34	0	0.75917756	FALSE	1	MDH1	133848	0.05805296
787484	taxon:9606	2.49283126	7.74E-05	179348	1902	mitogen-activated protein kinase kinase kinase 11	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007256-&&-activation of JNKK activity-%%-GO:0007254-&&-JNK cascade-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008219-&&-cell death-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0016020-&&-membrane-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004706-&&-JUN kinase kinase kinase activity-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAP3K11			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04010-&&-MAPK signaling pathway	MAP3K11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K11	0.4011503	0.17613636	35	4	FALSE	MAP3K11	MAP3K11	186.5151515	0	34	0	0.75119479	FALSE	1	MAP3K11	102712	0.05804072
787652	taxon:9606	2.57444462	4.94E-05	179010	1902	neurotrophic receptor tyrosine kinase 2	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007612-&&-learning-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0046548-&&-retinal rod cell development-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007631-&&-feeding behavior-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0007623-&&-circadian rhythm-%%-GO:0031547-&&-brain-derived neurotrophic factor receptor signaling pathway-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0014047-&&-glutamate secretion-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0038179-&&-neurotrophin signaling pathway-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001764-&&-neuron migration-%%-GO:0042490-&&-mechanoreceptor differentiation-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043087-&&-regulation of GTPase activity|cellular_component-&-1&-GO:0010008-&&-endosome membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005769-&&-early endosome-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043195-&&-terminal bouton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0043121-&&-neurotrophin binding-%%-GO:0048403-&&-brain-derived neurotrophic factor binding-%%-GO:0060175-&&-brain-derived neurotrophic factor-activated receptor activity-%%-GO:0005524-&&-ATP binding	G:9606:NTRK2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway	NTRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTRK2	0.38843329	0.12121212	35	4	FALSE	NTRK2	NTRK2	145.7272727	0	34	0	0.73759256	FALSE	1	NTRK2	68954	0.05379124
787842	taxon:9606	2.50606586	6.93E-05	178731	1902	mitogen-activated protein kinase kinase 2	gene	biological_process-&-1&-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090170-&&-regulation of Golgi inheritance-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0035897-&&-proteolysis in other organism-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0005770-&&-late endosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0005524-&&-ATP binding	G:9606:MAP2K2			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa05020-&&-Prion diseases-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	MAP2K2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K2	0.39903181	0.14772727	35	4	FALSE	MAP2K2	MAP2K2	176.4242424	0	34	0	0.74898902	FALSE	1	MAP2K2	113198	0.0557921
788140	taxon:9606	2.60438002	7.71E-05	178168	1902	glycogen phosphorylase L	gene	biological_process-&-1&-GO:0005980-&&-glycogen catabolic process-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0006015-&&-5-phosphoribose 1-diphosphate biosynthetic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0070266-&&-necroptotic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0008184-&&-glycogen phosphorylase activity-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019842-&&-vitamin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005536-&&-glucose binding-%%-GO:0032052-&&-bile acid binding-%%-GO:0002060-&&-purine nucleobase binding-%%-GO:0016208-&&-AMP binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PYGL			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa04217-&&-Necroptosis	PYGL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYGL	0.38396854	0.10795455	35	4	FALSE	PYGL	PYGL	155.2121212	0	34	0	0.73260333	FALSE	1	PYGL	105170	0.06110753
788319	taxon:9606	2.68016386	5.09E-05	177899	1902	S100 calcium binding protein A10	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0006900-&&-membrane budding-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0001765-&&-membrane raft assembly-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:S100A10				S100A10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A10	0.37311152	0.05681818	35	4	FALSE	S100A10	S100A10	107.3939394	0	34	0	0.71997269	FALSE	1	S100A10	65180	0.05214597
788447	taxon:9606	2.47156137	7.25E-05	177659	1902	solute carrier family 1 member 5	gene	biological_process-&-1&-GO:0006860-&&-extracellular amino acid transport-%%-GO:0015804-&&-neutral amino acid transport-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0003333-&&-amino acid transmembrane transport-%%-GO:0006868-&&-glutamine transport-%%-GO:0015825-&&-L-serine transport-%%-GO:0006865-&&-amino acid transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0015175-&&-neutral amino acid transmembrane transporter activity-%%-GO:0015186-&&-L-glutamine transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0015171-&&-amino acid transmembrane transporter activity-%%-GO:0015194-&&-L-serine transmembrane transporter activity-%%-GO:0015293-&&-symporter activity	G:9606:SLC1A5			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04974-&&-Protein digestion and absorption	SLC1A5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC1A5	0.40460254	0.07563025	35	4	FALSE	SLC1A5	SLC1A5	252.1142857	0	35	0	0.75473977	FALSE	0	SLC1A5	160244	0.07513953
788503	taxon:9606	2.4958248	3.46E-05	177543	1902	small nuclear ribonucleoprotein polypeptide N	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0008380-&&-RNA splicing-%%-GO:0009725-&&-response to hormone|cellular_component-&-1&-GO:0005686-&&-U2 snRNP-%%-GO:0071004-&&-U2-type prespliceosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005687-&&-U4 snRNP-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005685-&&-U1 snRNP|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNRPN				SNRPN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRPN	0.40066915	0.12773109	35	4	FALSE	SNRPN	SNRPN	205.3142857	0	35	0	0.75069587	FALSE	0	SNRPN	86704	0.06366257
788593	taxon:9606	2.71277769	1.11E-04	177379	1902	thromboxane A2 receptor	gene	biological_process-&-1&-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0038193-&&-thromboxane A2 signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007584-&&-response to nutrient-%%-GO:0033574-&&-response to testosterone-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045471-&&-response to ethanol|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0001669-&&-acrosomal vesicle|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004961-&&-thromboxane A2 receptor activity	G:9606:TBXA2R			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	TBXA2R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBXA2R	0.36862586	0.07386364	35	4	FALSE	TBXA2R	TBXA2R	96.36363636	0	34	0	0.71453705	FALSE	1	TBXA2R	118838	0.05169436
789022	taxon:9606	2.477706	3.32E-05	176359	1902	clathrin heavy chain like 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0046326-&&-positive regulation of glucose import|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005770-&&-late endosome-%%-GO:0016020-&&-membrane-%%-GO:0030130-&&-clathrin coat of trans-Golgi network vesicle-%%-GO:0097443-&&-sorting endosome-%%-GO:0055037-&&-recycling endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:0005769-&&-early endosome-%%-GO:0030135-&&-coated vesicle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:CLTCL1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04142-&&-Lysosome	CLTCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLTCL1	0.40359914	0.21680672	35	4	FALSE	CLTCL1	CLTCL1	245.9428571	0	35	0	0.75371567	FALSE	0	CLTCL1	73010	0.07421845
789083	taxon:9606	2.56121002	6.24E-05	176226	1902	cyclin dependent kinase 5 regulatory subunit 1	gene	biological_process-&-1&-GO:0007413-&&-axonal fasciculation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0021766-&&-hippocampus development-%%-GO:0021549-&&-cerebellum development-%%-GO:0007420-&&-brain development-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0031175-&&-neuron projection development-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0007411-&&-axon guidance-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0021722-&&-superior olivary nucleus maturation-%%-GO:0009790-&&-embryo development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0001764-&&-neuron migration-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007158-&&-neuron cell-cell adhesion-%%-GO:0033136-&&-serine phosphorylation of STAT3 protein-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0048511-&&-rhythmic process-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0043292-&&-contractile fiber-%%-GO:0016533-&&-cyclin-dependent protein kinase 5 holoenzyme complex-%%-GO:0005829-&&-cytosol-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043197-&&-dendritic spine-%%-GO:0043025-&&-neuronal cell body-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0016534-&&-cyclin-dependent protein kinase 5 activator activity	G:9606:CDK5R1			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05030-&&-Cocaine addiction	CDK5R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK5R1	0.39044045	0.08143939	35	5	FALSE	CDK5R1	CDK5R1	153.030303	0	34	0	0.73979833	FALSE	1	CDK5R1	108188	0.05458007
789119	taxon:9606	2.64786513	2.00E-05	176162	1902	methyl-CpG binding domain protein 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0042711-&&-maternal behavior-%%-GO:0048568-&&-embryonic organ development-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043044-&&-ATP-dependent chromatin remodeling|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0000118-&&-histone deacetylase complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0031492-&&-nucleosomal DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0003696-&&-satellite DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0035197-&&-siRNA binding	G:9606:MBD2				MBD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBD2	0.37766274	0.30113636	35	5	FALSE	MBD2	MBD2	154.4848485	0	34	0	0.72535581	FALSE	1	MBD2	40074	0.06686615
789277	taxon:9606	2.62880101	3.41E-05	175843	1902	endothelial differentiation related factor 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045446-&&-endothelial cell differentiation-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0019216-&&-regulation of lipid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008168-&&-methyltransferase activity	G:9606:EDF1				EDF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EDF1	0.38040156	0.19663866	35	4	FALSE	EDF1	EDF1	220	0	35	0	0.72853317	FALSE	0	EDF1	86004	0.09207944
789289	taxon:9606	2.71072948	1.20E-04	175817	1902	family with sequence similarity 189 member A2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:FAM189A2				FAM189A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM189A2	0.36890439	0.06554622	35	4	FALSE	FAM189A2	FAM189A2	92.57142857	0	35	0	0.71487842	FALSE	0	FAM189A2	110242	0.04915138
789318	taxon:9606	2.696392	5.07E-05	175752	1902	A-kinase anchoring protein 5	gene	biological_process-&-1&-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007165-&&-signal transduction-%%-GO:0006605-&&-protein targeting-%%-GO:0010739-&&-positive regulation of protein kinase A signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0008179-&&-adenylate cyclase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:AKAP5				AKAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP5	0.37086596	0.17142857	35	4	FALSE	AKAP5	AKAP5	183.3714286	0	35	0	0.717268	FALSE	0	AKAP5	103266	0.09311847
789384	taxon:9606	2.53946746	5.14E-05	175612	1902	pituitary tumor-transforming 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051276-&&-chromosome organization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0045143-&&-homologous chromosome segregation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030414-&&-peptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:PTTG1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	PTTG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTTG1	0.39378335	0.14015152	35	4	FALSE	PTTG1	PTTG1	175.7272727	0	34	0	0.74342209	FALSE	1	PTTG1	74598	0.05967936
789469	taxon:9606	2.71907988	6.02E-05	175392	1902	cAMP responsive element binding protein 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:CREB5			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa05016-&&-Huntington disease-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB5	0.36777147	0.20075758	35	4	FALSE	CREB5	CREB5	104.6060606	0	34	0	0.71348669	FALSE	1	CREB5	96480	0.05737773
789525	taxon:9606	2.50779896	3.47E-05	175266	1902	ATP binding cassette subfamily F member 2	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005740-&&-mitochondrial envelope-%%-GO:0016020-&&-membrane-%%-GO:0043190-&&-ATP-binding cassette (ABC) transporter complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005215-&&-transporter activity-%%-GO:0016887-&&-ATPase activity	G:9606:ABCF2				ABCF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCF2	0.39875605	0.14789916	35	4	FALSE	ABCF2	ABCF2	222.0571429	0	35	0	0.74870017	FALSE	0	ABCF2	64388	0.07067813
789839	taxon:9606	2.61273042	6.42E-05	174536	1902	ralA binding protein 1	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0055085-&&-transmembrane transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0006810-&&-transport-%%-GO:0006897-&&-endocytosis-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0048365-&&-Rac GTPase binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0043492-&&-ATPase activity, coupled to movement of substances-%%-GO:0005515-&&-protein binding-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:RALBP1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05200-&&-Pathways in cancer	RALBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RALBP1	0.38274136	0.1092437	35	4	FALSE	RALBP1	RALBP1	120.2285714	0	35	0	0.7312116	FALSE	0	RALBP1	81166	0.04831273
789911	taxon:9606	2.58500079	8.10E-05	174382	1902	exocyst complex component 5	gene	biological_process-&-1&-GO:0006887-&&-exocytosis-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0048278-&&-vesicle docking-%%-GO:0006893-&&-Golgi to plasma membrane transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000145-&&-exocyst|molecular_function-&-1&-GO:0017160-&&-Ral GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:EXOC5				EXOC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC5	0.38684708	0.12878788	35	4	FALSE	EXOC5	EXOC5	141.6666667	0	34	0	0.7358332	FALSE	1	EXOC5	92882	0.05278702
789915	taxon:9606	2.78021112	6.99E-05	174372	1902	YKT6 v-SNARE homolog (S. cerevisiae)	gene	biological_process-&-1&-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006906-&&-vesicle fusion-%%-GO:0006903-&&-vesicle targeting-%%-GO:0042147-&&-retrograde transport, endosome to Golgi|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0097441-&&-basilar dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0097440-&&-apical dendrite-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043025-&&-neuronal cell body-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031201-&&-SNARE complex|molecular_function-&-1&-GO:0019706-&&-protein-cysteine S-palmitoyltransferase activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0005484-&&-SNAP receptor activity	G:9606:YKT6			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport	YKT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YKT6	0.35968491	0.09747899	35	4	FALSE	YKT6	YKT6	78.6	0	35	0	0.70329815	FALSE	0	YKT6	76454	0.05255
790117	taxon:9606	2.67212856	3.10E-05	173846	1902	programmed cell death 10	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0050821-&&-protein stabilization-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0001525-&&-angiogenesis-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0036481-&&-intrinsic apoptotic signaling pathway in response to hydrogen peroxide-%%-GO:0051683-&&-establishment of Golgi localization-%%-GO:1903588-&&-negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis-%%-GO:0090168-&&-Golgi reassembly-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PDCD10				PDCD10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD10	0.37423349	0.21512605	35	4	FALSE	PDCD10	PDCD10	134.6571429	0	35	0	0.72131191	FALSE	0	PDCD10	51786	0.06365417
790123	taxon:9606	2.48526863	2.86E-05	173826	1902	exportin for tRNA	gene	biological_process-&-1&-GO:0071528-&&-tRNA re-export from nucleus-%%-GO:0006409-&&-tRNA export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005643-&&-nuclear pore-%%-GO:0005737-&&-cytoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0015932-&&-nucleobase-containing compound transmembrane transporter activity-%%-GO:0000049-&&-tRNA binding-%%-GO:0005515-&&-protein binding	G:9606:XPOT			KEGG-&-1&-hsa03013-&&-RNA transport	XPOT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPOT	0.40237099	0.1092437	35	4	FALSE	XPOT	XPOT	230.4857143	0	35	0	0.75245523	FALSE	0	XPOT	78524	0.07022249
790168	taxon:9606	2.51536159	5.94E-05	173724	1902	palladin, cytoskeletal associated protein	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0003382-&&-epithelial cell morphogenesis-%%-GO:0003334-&&-keratinocyte development-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0005884-&&-actin filament-%%-GO:0001726-&&-ruffle-%%-GO:0030424-&&-axon-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0002102-&&-podosome-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0051371-&&-muscle alpha-actinin binding	G:9606:PALLD				PALLD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PALLD	0.39755716	0.12941176	35	4	FALSE	PALLD	PALLD	171.9142857	0	35	0	0.74743974	FALSE	0	PALLD	100598	0.05549149
790202	taxon:9606	2.52733575	2.85E-05	173654	1902	spastic paraplegia 20 (Troyer syndrome)	gene	biological_process-&-1&-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0050905-&&-neuromuscular process-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0034389-&&-lipid particle organization-%%-GO:0051301-&&-cell division-%%-GO:0048698-&&-negative regulation of collateral sprouting in absence of injury-%%-GO:0009838-&&-abscission-%%-GO:0060612-&&-adipose tissue development|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0045202-&&-synapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:SPG20			KEGG-&-1&-hsa04144-&&-Endocytosis	SPG20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPG20	0.39567359	0.12268908	35	4	FALSE	SPG20	SPG20	173.2	0	35	0	0.74544404	FALSE	0	SPG20	62812	0.05741758
790461	taxon:9606	2.51221049	1.79E-04	172791	1902	listerin E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0051865-&&-protein autoubiquitination|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:LTN1				LTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTN1	0.39805582	0.0789916	35	4	FALSE	LTN1	LTN1	175.0857143	0	35	0	0.74796492	FALSE	0	LTN1	205216	0.0563147
790480	taxon:9606	2.76855207	3.35E-05	172734	1902	FGFR1 oncogene partner 2	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:FGFR1OP2				FGFR1OP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGFR1OP2	0.36119964	0.17815126	35	4	FALSE	FGFR1OP2	FGFR1OP2	83.8	0	35	0	0.70524132	FALSE	0	FGFR1OP2	41264	0.05489314
790530	taxon:9606	2.6716559	3.47E-05	172587	1902	LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0005829-&&-cytosol-%%-GO:0005688-&&-U6 snRNP-%%-GO:0005634-&&-nucleus-%%-GO:1990726-&&-Lsm1-7-Pat1 complex-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0000932-&&-P-body-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LSM3			KEGG-&-1&-hsa03040-&&-Spliceosome-%%-hsa03018-&&-RNA degradation	LSM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM3	0.3742997	0.12436975	35	4	FALSE	LSM3	LSM3	127.3428571	0	35	0	0.72139068	FALSE	0	LSM3	57666	0.05959298
790534	taxon:9606	2.60501024	1.90E-04	172552	1902	ribosomal protein S6 kinase A6	gene	biological_process-&-1&-GO:0045992-&&-negative regulation of embryonic development-%%-GO:2000381-&&-negative regulation of mesoderm development-%%-GO:0006978-&&-DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0016301-&&-kinase activity	G:9606:RPS6KA6			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	RPS6KA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA6	0.38387565	0.03529412	35	4	FALSE	RPS6KA6	RPS6KA6	108.2285714	0	35	0	0.73249829	FALSE	0	RPS6KA6	163610	0.04273814
790633	taxon:9606	2.37056877	3.46E-05	171707	1902	YTH N6-methyladenosine RNA binding protein 2	gene	biological_process-&-1&-GO:1903679-&&-positive regulation of cap-independent translational initiation-%%-GO:0006959-&&-humoral immune response-%%-GO:0043488-&&-regulation of mRNA stability|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0005515-&&-protein binding	G:9606:YTHDF2				YTHDF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YTHDF2	0.42183969	0.22857143	35	4	FALSE	YTHDF2	YTHDF2	366.0285714	0	35	0	0.77157187	FALSE	0	YTHDF2	95576	0.09181421
790662	taxon:9606	2.51867024	2.46E-05	171552	1902	mitochondrial ribosomal protein S18B	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS18B			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	MRPS18B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS18B	0.39703491	0.28907563	35	4	FALSE	MRPS18B	MRPS18B	209.3142857	0	35	0	0.74688829	FALSE	0	MRPS18B	60048	0.06817124
790822	taxon:9606	2.53206239	6.22E-05	171076	1902	myelin expression factor 2	gene	biological_process-&-1&-GO:0030182-&&-neuron differentiation-%%-GO:0014902-&&-myotube differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding	G:9606:MYEF2				MYEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYEF2	0.39493498	0.1092437	35	4	FALSE	MYEF2	MYEF2	223.6857143	0	35	0	0.74465627	FALSE	0	MYEF2	108194	0.07447619
790864	taxon:9606	2.56735466	1.07E-04	170849	1902	F-box and WD repeat domain containing 5	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:FBXW5				FBXW5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW5	0.38950598	0.1210084	35	4	FALSE	FBXW5	FBXW5	161.3714286	0	35	0	0.73877422	FALSE	0	FBXW5	151664	0.05806916
790987	taxon:9606	2.49487947	1.29E-05	170491	1902	RNA binding motif protein 28	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBM28			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	RBM28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM28	0.40082097	0.37815126	35	4	FALSE	RBM28	RBM28	302.7714286	0	35	0	0.75085342	FALSE	0	RBM28	42792	0.09397003
791036	taxon:9606	2.41547188	1.12E-04	170284	1902	YTH N6-methyladenosine RNA binding protein 1	gene	biological_process-&-1&-GO:0045948-&&-positive regulation of translational initiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0043022-&&-ribosome binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding	G:9606:YTHDF1				YTHDF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YTHDF1	0.41399778	0.13445378	35	4	FALSE	YTHDF1	YTHDF1	263.6571429	0	35	0	0.76408802	FALSE	0	YTHDF1	153758	0.07087528
791060	taxon:9606	2.51835513	5.84E-05	170199	1902	CDKN2A interacting protein	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0001652-&&-granular component-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0002039-&&-p53 binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CDKN2AIP				CDKN2AIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN2AIP	0.39708458	0.16302521	35	4	FALSE	CDKN2AIP	CDKN2AIP	222.6571429	0	35	0	0.74694081	FALSE	0	CDKN2AIP	91296	0.07237661
791152	taxon:9606	2.56184024	4.63E-05	169877	1902	BTB domain containing 2	gene	biological_process-&-1&-GO:0030162-&&-regulation of proteolysis-%%-GO:0022008-&&-neurogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:BTBD2				BTBD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTBD2	0.3903444	0.15719697	35	4	FALSE	BTBD2	BTBD2	184.2424242	0	34	0	0.73969329	FALSE	1	BTBD2	84976	0.06563314
791402	taxon:9606	2.6169844	5.72E-05	168779	1902	coiled-coil domain containing 14	gene	biological_process-&-1&-GO:0021762-&&-substantia nigra development-%%-GO:0071539-&&-protein localization to centrosome|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC14				CCDC14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC14	0.38211921	0.18319328	35	4	FALSE	CCDC14	CCDC14	117.1428571	0	35	0	0.7305026	FALSE	0	CCDC14	78620	0.0477591
791420	taxon:9606	2.61808729	2.94E-05	168706	1902	mitochondrial ribosomal protein S26	gene	biological_process-&-1&-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0043043-&&-peptide biosynthetic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:MRPS26				MRPS26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS26	0.38195824	0.24033613	35	4	FALSE	MRPS26	MRPS26	183.3714286	0	35	0	0.73031879	FALSE	0	MRPS26	53550	0.07451345
791465	taxon:9606	2.63951473	4.75E-05	168524	1902	TATA-box binding protein associated factor, RNA polymerase I subunit D	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0005668-&&-RNA polymerase transcription factor SL1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TAF1D				TAF1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1D	0.37885752	0.08067227	35	5	FALSE	TAF1D	TAF1D	115.1714286	0	35	0	0.72674754	FALSE	0	TAF1D	66310	0.04946805
791493	taxon:9606	2.44729794	3.80E-05	168395	1902	non-SMC condensin I complex subunit G	gene	biological_process-&-1&-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:0000796-&&-condensin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NCAPG				NCAPG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPG	0.40861392	0.20840336	35	4	FALSE	NCAPG	NCAPG	238.2285714	0	35	0	0.75878368	FALSE	0	NCAPG	87764	0.06788259
791543	taxon:9606	2.69103513	3.41E-05	168130	1902	basic helix-loop-helix family member e41	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008283-&&-cell proliferation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0043426-&&-MRF binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:BHLHE41			KEGG-&-1&-hsa04710-&&-Circadian rhythm	BHLHE41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BHLHE41	0.37160422	0.19886364	35	4	FALSE	BHLHE41	BHLHE41	116.3333333	0	34	0	0.71816081	FALSE	1	BHLHE41	50788	0.05681263
791546	taxon:9606	2.57223885	6.69E-05	168116	1902	FYVE and coiled-coil domain containing 1	gene	biological_process-&-1&-GO:1901098-&&-positive regulation of autophagosome maturation-%%-GO:0072383-&&-plus-end-directed vesicle transport along microtubule-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0006458-&&-'de novo' protein folding|cellular_component-&-1&-GO:0005776-&&-autophagosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005832-&&-chaperonin-containing T-complex-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:FYCO1				FYCO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FYCO1	0.38876638	0.07731092	35	4	FALSE	FYCO1	FYCO1	158.6857143	0	35	0	0.73796019	FALSE	0	FYCO1	94504	0.05802166
791555	taxon:9606	2.44745549	5.26E-05	168054	1902	mitochondrial ribosomal protein L24	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPL24			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL24	0.40858761	0.30252101	35	4	FALSE	MRPL24	MRPL24	243.7142857	0	35	0	0.75875742	FALSE	0	MRPL24	89550	0.06946108
791593	taxon:9606	2.56593666	1.23E-04	167896	1902	CDK5 regulatory subunit associated protein 3	gene	biological_process-&-1&-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901798-&&-positive regulation of signal transduction by p53 class mediator-%%-GO:0007420-&&-brain development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0030262-&&-apoptotic nuclear changes-%%-GO:0010921-&&-regulation of phosphatase activity-%%-GO:0071569-&&-protein ufmylation-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0044818-&&-mitotic G2/M transition checkpoint-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:1903363-&&-negative regulation of cellular protein catabolic process|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0012505-&&-endomembrane system-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0097371-&&-MDM2/MDM4 family protein binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0044389-&&-ubiquitin-like protein ligase binding	G:9606:CDK5RAP3				CDK5RAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK5RAP3	0.38972123	0.1092437	35	4	FALSE	CDK5RAP3	CDK5RAP3	161.1142857	0	35	0	0.73901056	FALSE	0	CDK5RAP3	129652	0.05820795
791669	taxon:9606	2.64077517	6.14E-05	167523	1902	DSN1 homolog, MIS12 kinetochore complex component	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000444-&&-MIS12/MIND type complex-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DSN1				DSN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSN1	0.37867669	0.11363636	35	5	FALSE	DSN1	DSN1	109.8181818	0	34	0	0.72653747	FALSE	1	DSN1	74042	0.04727011
791723	taxon:9606	2.66362061	3.53E-05	167199	1902	SRA stem-loop interacting RNA binding protein	gene	biological_process-&-1&-GO:0030317-&&-flagellated sperm motility-%%-GO:0007338-&&-single fertilization-%%-GO:0000961-&&-negative regulation of mitochondrial RNA catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus-%%-GO:0036126-&&-sperm flagellum-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:SLIRP				SLIRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLIRP	0.37542884	0.06890756	35	4	FALSE	SLIRP	SLIRP	124.8857143	0	35	0	0.7227299	FALSE	0	SLIRP	59338	0.05724785
791746	taxon:9606	2.44461951	2.15E-05	167083	1902	glutamate rich WD repeat containing 1	gene	biological_process-&-1&-GO:0006337-&&-nucleosome disassembly-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0006260-&&-DNA replication|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003688-&&-DNA replication origin binding-%%-GO:0042393-&&-histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:GRWD1				GRWD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRWD1	0.40906161	0.25882353	35	4	FALSE	GRWD1	GRWD1	293.9714286	0	35	0	0.75923008	FALSE	0	GRWD1	68110	0.08319114
791751	taxon:9606	2.4477706	3.83E-05	167061	1902	ATPase family, AAA domain containing 3B	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:ATAD3B				ATAD3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD3B	0.40853502	0.14789916	35	4	FALSE	ATAD3B	ATAD3B	248.9428571	0	35	0	0.7587049	FALSE	0	ATAD3B	94018	0.07090761
791820	taxon:9606	2.61083977	7.29E-05	166703	1902	protein phosphatase 1 regulatory subunit 9B	gene	biological_process-&-1&-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0046847-&&-filopodium assembly-%%-GO:0007399-&&-nervous system development-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0001560-&&-regulation of cell growth by extracellular stimulus-%%-GO:0008380-&&-RNA splicing-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0016477-&&-cell migration-%%-GO:0030154-&&-cell differentiation-%%-GO:2000474-&&-regulation of opioid receptor signaling pathway-%%-GO:0071315-&&-cellular response to morphine-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043197-&&-dendritic spine-%%-GO:0005912-&&-adherens junction-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032587-&&-ruffle membrane-%%-GO:0000164-&&-protein phosphatase type 1 complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0005515-&&-protein binding	G:9606:PPP1R9B				PPP1R9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R9B	0.38301853	0.15966387	35	4	FALSE	PPP1R9B	PPP1R9B	151.4571429	0	35	0	0.73152671	FALSE	0	PPP1R9B	89500	0.060358
791846	taxon:9606	2.63478809	1.44E-04	182981	1902	ATP binding cassette subfamily A member 1	gene	biological_process-&-1&-GO:0033344-&&-cholesterol efflux-%%-GO:0050702-&&-interleukin-1 beta secretion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0055098-&&-response to low-density lipoprotein particle-%%-GO:0098656-&&-anion transmembrane transport-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0033700-&&-phospholipid efflux-%%-GO:0055091-&&-phospholipid homeostasis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007584-&&-response to nutrient-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0045332-&&-phospholipid translocation-%%-GO:0002790-&&-peptide secretion-%%-GO:0071397-&&-cellular response to cholesterol-%%-GO:0007040-&&-lysosome organization-%%-GO:0010887-&&-negative regulation of cholesterol storage-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0032489-&&-regulation of Cdc42 protein signal transduction-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0060155-&&-platelet dense granule organization-%%-GO:0016197-&&-endosomal transport-%%-GO:0015917-&&-aminophospholipid transport-%%-GO:0006497-&&-protein lipidation-%%-GO:0090107-&&-regulation of high-density lipoprotein particle assembly-%%-GO:0038027-&&-apolipoprotein A-I-mediated signaling pathway-%%-GO:0034380-&&-high-density lipoprotein particle assembly-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0032367-&&-intracellular cholesterol transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0034364-&&-high-density lipoprotein particle-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0051117-&&-ATPase binding-%%-GO:0017127-&&-cholesterol transporter activity-%%-GO:0005548-&&-phospholipid transporter activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0031267-&&-small GTPase binding-%%-GO:0034188-&&-apolipoprotein A-I receptor activity-%%-GO:0008509-&&-anion transmembrane transporter activity-%%-GO:0090556-&&-phosphatidylserine-translocating ATPase activity-%%-GO:0034186-&&-apolipoprotein A-I binding-%%-GO:0090554-&&-phosphatidylcholine-translocating ATPase activity	G:9606:ABCA1	ABCA1	TRUE	KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa02010-&&-ABC transporters	ABCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCA1	0.37953716	0.02521008	35	4	FALSE	ABCA1	ABCA1	103.4285714	0	35	0	0.72753532	FALSE	0	ABCA1	141590	0.0443337
791891	taxon:9606	2.66582637	4.81E-05	182917	1902	adenylosuccinate synthase	gene	biological_process-&-1&-GO:0006167-&&-AMP biosynthetic process-%%-GO:0014074-&&-response to purine-containing compound-%%-GO:0044208-&&-'de novo' AMP biosynthetic process-%%-GO:0002376-&&-immune system process-%%-GO:0006531-&&-aspartate metabolic process-%%-GO:0046040-&&-IMP metabolic process-%%-GO:0071257-&&-cellular response to electrical stimulus-%%-GO:0060359-&&-response to ammonium ion-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004019-&&-adenylosuccinate synthase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0042301-&&-phosphate ion binding	G:9606:ADSS			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	ADSS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADSS	0.3751182	0.12773109	35	4	FALSE	ADSS	ADSS	105.9428571	0	35	0	0.72236227	FALSE	0	ADSS	63838	0.04861211
791927	taxon:9606	2.48101465	9.93E-05	182867	1902	aldehyde dehydrogenase 1 family member B1	gene	biological_process-&-1&-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0006068-&&-ethanol catabolic process-%%-GO:0006069-&&-ethanol oxidation|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity	G:9606:ALDH1B1			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00340-&&-Histidine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	ALDH1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH1B1	0.4030609	0.12941176	35	4	FALSE	ALDH1B1	ALDH1B1	210.7428571	0	35	0	0.75316422	FALSE	0	ALDH1B1	129950	0.06390225
792051	taxon:9606	2.78336222	1.72E-05	166302	1902	methyltransferase like 18	gene	biological_process-&-1&-GO:0032259-&&-methylation|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity	G:9606:METTL18				METTL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL18	0.35927771	0.08571429	35	4	FALSE	METTL18	METTL18	99.11428571	0	35	0	0.70277296	FALSE	0	METTL18	31108	0.0680759
792192	taxon:9606	2.84213014	3.96E-05	166069	1902	transmembrane protein 67	gene	biological_process-&-1&-GO:0010826-&&-negative regulation of centrosome duplication-%%-GO:0060271-&&-cilium assembly-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005813-&&-centrosome-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0036038-&&-MKS complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0031005-&&-filamin binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:TMEM67				TMEM67	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM67	0.35184877	0.06722689	35	4	FALSE	TMEM67	TMEM67	63.74285714	0	35	0	0.69297831	FALSE	0	TMEM67	45150	0.05706557
792259	taxon:9606	2.48416575	8.02E-05	182338	1902	kinesin family member 1A	gene	biological_process-&-1&-GO:0008089-&&-anterograde axonal transport|cellular_component-&-1&-GO:0005871-&&-kinesin complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003777-&&-microtubule motor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0003774-&&-motor activity-%%-GO:0008017-&&-microtubule binding	G:9606:KIF1A				KIF1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF1A	0.40254963	0.08333333	35	4	FALSE	KIF1A	KIF1A	200.3636364	0	34	0	0.75263904	FALSE	1	KIF1A	150460	0.06092883
792275	taxon:9606	2.47849378	2.93E-05	182310	1902	cell division cycle 25B	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0001556-&&-oocyte maturation-%%-GO:0007144-&&-female meiosis I|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:CDC25B			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC25B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC25B	0.40347085	0.18823529	35	4	FALSE	CDC25B	CDC25B	237.6	0	35	0	0.75358437	FALSE	0	CDC25B	65338	0.07157496
792302	taxon:9606	2.70773594	6.21E-05	182256	1902	CCAAT/enhancer binding protein epsilon	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006952-&&-defense response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0042089-&&-cytokine biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006909-&&-phagocytosis-%%-GO:0030225-&&-macrophage differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:CEBPE			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia	CEBPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPE	0.36931223	0.19318182	35	4	FALSE	CEBPE	CEBPE	102.6060606	0	34	0	0.71537734	FALSE	1	CEBPE	69188	0.05310096
792356	taxon:9606	2.5821648	5.45E-05	165786	1902	mitochondrial ribosomal protein L53	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MRPL53				MRPL53	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL53	0.38727195	0.10084034	35	4	FALSE	MRPL53	MRPL53	131.9714286	0	35	0	0.73630587	FALSE	0	MRPL53	85290	0.049374
792389	taxon:9606	2.66031196	7.91E-05	182106	1902	cAMP responsive element modulator	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0030154-&&-cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008140-&&-cAMP response element binding protein binding	G:9606:CREM			KEGG-&-1&-hsa04261-&&-Adrenergic signaling in cardiomyocytes	CREM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREM	0.37589577	0.14015152	35	4	FALSE	CREM	CREM	128.5151515	0	34	0	0.72328134	FALSE	1	CREM	102480	0.05777196
792413	taxon:9606	2.63210966	1.06E-04	165677	1902	TP53 regulating kinase	gene	biological_process-&-1&-GO:0070525-&&-tRNA threonylcarbamoyladenosine metabolic process-%%-GO:0008033-&&-tRNA processing-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0000408-&&-EKC/KEOPS complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:TP53RK				TP53RK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53RK	0.37992338	0.16134454	35	4	FALSE	TP53RK	TP53RK	109.4857143	0	35	0	0.72798172	FALSE	0	TP53RK	110668	0.04604646
792463	taxon:9606	2.77532693	4.34E-05	165594	1902	NLR family pyrin domain containing 3	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:2000321-&&-positive regulation of T-helper 17 cell differentiation-%%-GO:2000553-&&-positive regulation of T-helper 2 cell cytokine production-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0009595-&&-detection of biotic stimulus-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0006952-&&-defense response-%%-GO:0050701-&&-interleukin-1 secretion-%%-GO:0051259-&&-protein oligomerization-%%-GO:0032736-&&-positive regulation of interleukin-13 production-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0032611-&&-interleukin-1 beta production-%%-GO:0006954-&&-inflammatory response-%%-GO:0006915-&&-apoptotic process-%%-GO:0032621-&&-interleukin-18 production-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0032754-&&-positive regulation of interleukin-5 production-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050713-&&-negative regulation of interleukin-1 beta secretion-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0051607-&&-defense response to virus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0044546-&&-NLRP3 inflammasome complex assembly-%%-GO:0002830-&&-positive regulation of type 2 immune response-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042834-&&-peptidoglycan binding-%%-GO:0005524-&&-ATP binding	G:9606:NLRP3	NLRP3	TRUE	KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis	NLRP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP3	0.36031791	0.02651515	35	4	FALSE	NLRP3	NLRP3	78.75757576	0	34	0	0.70411218	FALSE	1	NLRP3	49006	0.05214705
792864	taxon:9606	2.68079408	3.41E-05	181249	1902	estrogen related receptor alpha	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:1900078-&&-positive regulation of cellular response to insulin stimulus-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0051216-&&-cartilage development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005496-&&-steroid binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ESRRA				ESRRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESRRA	0.3730238	0.10606061	35	4	FALSE	ESRRA	ESRRA	117.969697	0	34	0	0.71986765	FALSE	1	ESRRA	49116	0.05619651
793015	taxon:9606	2.61162754	5.58E-05	180889	1902	MAP kinase interacting serine/threonine kinase 2	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006417-&&-regulation of translation-%%-GO:0030097-&&-hemopoiesis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0071243-&&-cellular response to arsenic-containing substance|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MKNK2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	MKNK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKNK2	0.38290299	0.07386364	35	4	FALSE	MKNK2	MKNK2	135.9393939	0	34	0	0.73139541	FALSE	1	MKNK2	68870	0.05448706
793088	taxon:9606	2.72648495	4.14E-06	164378	1902	proteasome subunit alpha 8	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:1990111-&&-spermatoproteasome complex-%%-GO:0019773-&&-proteasome core complex, alpha-subunit complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004298-&&-threonine-type endopeptidase activity	G:9606:PSMA8			KEGG-&-1&-hsa03050-&&-Proteasome	PSMA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMA8	0.36677261	0.81008403	35	4	FALSE	PSMA8	PSMA8	136.8285714	0	35	0	0.71225251	FALSE	0	PSMA8	12368	0.07534613
793161	taxon:9606	2.57003309	1.68E-04	180613	1902	G protein subunit alpha o1	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0006457-&&-protein folding-%%-GO:0034097-&&-response to cytokine-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043278-&&-response to morphine-%%-GO:0006936-&&-muscle contraction-%%-GO:0007568-&&-aging-%%-GO:0030900-&&-forebrain development-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0051430-&&-corticotropin-releasing hormone receptor 1 binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0031852-&&-mu-type opioid receptor binding	G:9606:GNAO1			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04916-&&-Melanogenesis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	GNAO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAO1	0.38910005	0.10416667	35	4	FALSE	GNAO1	GNAO1	122.2727273	0	34	0	0.73832782	FALSE	1	GNAO1	157750	0.04432712
793253	taxon:9606	2.56924531	1.33E-04	180443	1902	glucose-6-phosphate isomerase	gene	biological_process-&-1&-GO:0001707-&&-mesoderm formation-%%-GO:0007611-&&-learning or memory-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0033574-&&-response to testosterone-%%-GO:0001525-&&-angiogenesis-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0006959-&&-humoral immune response-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0043278-&&-response to morphine-%%-GO:0032355-&&-response to estradiol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007599-&&-hemostasis-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0032570-&&-response to progesterone-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0051156-&&-glucose 6-phosphate metabolic process-%%-GO:0019242-&&-methylglyoxal biosynthetic process-%%-GO:0046185-&&-aldehyde catabolic process-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0006094-&&-gluconeogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0060170-&&-ciliary membrane-%%-GO:0016020-&&-membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016866-&&-intramolecular transferase activity-%%-GO:0048029-&&-monosaccharide binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004347-&&-glucose-6-phosphate isomerase activity-%%-GO:0008083-&&-growth factor activity	G:9606:GPI			KEGG-&-1&-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00030-&&-Pentose phosphate pathway	GPI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPI	0.38921935	0.19318182	35	4	FALSE	GPI	GPI	189.5151515	0	34	0	0.73845911	FALSE	1	GPI	180894	0.06882047
793313	taxon:9606	2.42382228	5.03E-05	180331	1902	helicase, lymphoid-specific	gene	biological_process-&-1&-GO:0031508-&&-pericentric heterochromatin assembly-%%-GO:0007275-&&-multicellular organism development-%%-GO:0046651-&&-lymphocyte proliferation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006346-&&-methylation-dependent chromatin silencing-%%-GO:0010216-&&-maintenance of DNA methylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:HELLS				HELLS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HELLS	0.4125715	0.11428571	35	4	FALSE	HELLS	HELLS	256.1714286	0	35	0	0.76269629	FALSE	0	HELLS	130786	0.06992276
787107	taxon:9606	2.69040492	1.19E-04	180045	1902	interleukin 6 signal transducer	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0038165-&&-oncostatin-M-mediated signaling pathway-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0038154-&&-interleukin-11-mediated signaling pathway-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0008593-&&-regulation of Notch signaling pathway-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0048861-&&-leukemia inhibitory factor signaling pathway-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0016032-&&-viral process-%%-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0070120-&&-ciliary neurotrophic factor-mediated signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0070106-&&-interleukin-27-mediated signaling pathway-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0070110-&&-ciliary neurotrophic factor receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0030425-&&-dendrite-%%-GO:0005900-&&-oncostatin-M receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0005896-&&-interleukin-6 receptor complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0019838-&&-growth factor binding-%%-GO:0004923-&&-leukemia inhibitory factor receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005138-&&-interleukin-6 receptor binding-%%-GO:0004915-&&-interleukin-6 receptor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005127-&&-ciliary neurotrophic factor receptor binding-%%-GO:0019970-&&-interleukin-11 binding-%%-GO:0019981-&&-interleukin-6 binding-%%-GO:0004921-&&-interleukin-11 receptor activity-%%-GO:0004924-&&-oncostatin-M receptor activity-%%-GO:0045509-&&-interleukin-27 receptor activity-%%-GO:0004897-&&-ciliary neurotrophic factor receptor activity	G:9606:IL6ST	IL6ST	TRUE	KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL6ST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL6ST	0.37169126	0.18548387	34	4	FALSE	IL6ST	IL6ST	116.4375	0	33	0	0.71826585	FALSE	1	IL6ST	115218	0.05832915
787417	taxon:9606	2.49661257	9.02E-05	179468	1902	NADH:ubiquinone oxidoreductase subunit A5	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding	G:9606:NDUFA5			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFA5	0.40054272	0.1942959	34	4	FALSE	NDUFA5	NDUFA5	194.3235294	0	34	0	0.75056457	FALSE	0	NDUFA5	167272	0.06054662
787664	taxon:9606	2.73184182	3.21E-04	178993	1902	serpin family A member 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0006953-&&-acute-phase response-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001948-&&-glycoprotein binding	G:9606:SERPINA1			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	SERPINA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINA1	0.36605341	0.04435484	34	4	FALSE	SERPINA1	SERPINA1	76.8125	0	33	0	0.7113597	FALSE	1	SERPINA1	346042	0.04408901
787694	taxon:9606	2.72821806	1.98E-04	178935	1902	plasminogen activator, tissue type	gene	biological_process-&-1&-GO:0031639-&&-plasminogen activation-%%-GO:0006508-&&-proteolysis-%%-GO:0042730-&&-fibrinolysis-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0007596-&&-blood coagulation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0030141-&&-secretory granule-%%-GO:0045177-&&-apical part of cell-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding	G:9606:PLAT	PLAT	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04610-&&-Complement and coagulation cascades	PLAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLAT	0.36653962	0.08467742	34	4	FALSE	PLAT	PLAT	81.40625	0	33	0	0.71196366	FALSE	1	PLAT	193768	0.04626993
787984	taxon:9606	2.50259965	5.50E-05	178453	1902	phosphodiesterase 4D	gene	biological_process-&-1&-GO:0002027-&&-regulation of heart rate-%%-GO:0006198-&&-cAMP catabolic process-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032754-&&-positive regulation of interleukin-5 production-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0007568-&&-aging-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0030814-&&-regulation of cAMP metabolic process-%%-GO:1901844-&&-regulation of cell communication by electrical coupling involved in cardiac conduction-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0086024-&&-adrenergic receptor signaling pathway involved in positive regulation of heart rate-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:1901898-&&-negative regulation of relaxation of cardiac muscle-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0071875-&&-adrenergic receptor signaling pathway-%%-GO:0032743-&&-positive regulation of interleukin-2 production|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0034704-&&-calcium channel complex-%%-GO:0005813-&&-centrosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005891-&&-voltage-gated calcium channel complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0008144-&&-drug binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0004115-&&-3',5'-cyclic-AMP phosphodiesterase activity-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0004114-&&-3',5'-cyclic-nucleotide phosphodiesterase activity	G:9606:PDE4D			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa00230-&&-Purine metabolism	PDE4D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE4D	0.39958449	0.13306452	34	4	FALSE	PDE4D	PDE4D	200.5625	0	33	0	0.74956672	FALSE	1	PDE4D	91184	0.06344937
788133	taxon:9606	2.65322199	1.86E-04	145422	1902	occludin	gene	biological_process-&-1&-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0070673-&&-response to interleukin-18-%%-GO:0006461-&&-protein complex assembly-%%-GO:0071356-&&-cellular response to tumor necrosis factor|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:OCLN			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction	OCLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OCLN	0.37690024	0.07258065	34	4	FALSE	OCLN	OCLN	122.59375	0	33	0	0.724463	FALSE	1	OCLN	245490	0.055
788175	taxon:9606	2.45296991	6.13E-05	178124	1902	RAN binding protein 1	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0046604-&&-positive regulation of mitotic centrosome separation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0007051-&&-spindle organization-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005092-&&-GDP-dissociation inhibitor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:RANBP1			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	RANBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP1	0.40766909	0.12655971	34	4	FALSE	RANBP1	RANBP1	257.1470588	0	34	0	0.75783835	FALSE	0	RANBP1	115344	0.07394402
788220	taxon:9606	2.56262801	2.59E-05	178058	1902	RE1 silencing transcription factor	gene	biological_process-&-1&-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032348-&&-negative regulation of aldosterone biosynthetic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000706-&&-negative regulation of dense core granule biogenesis-%%-GO:2000798-&&-negative regulation of amniotic stem cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000065-&&-negative regulation of cortisol biosynthetic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0071257-&&-cellular response to electrical stimulus-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060379-&&-cardiac muscle cell myoblast differentiation-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:2000740-&&-negative regulation of mesenchymal stem cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0070933-&&-histone H4 deacetylation-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0015271-&&-outward rectifier potassium channel activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:REST			KEGG-&-1&-hsa05016-&&-Huntington disease-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	REST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REST	0.39022441	0.14973262	34	4	FALSE	REST	REST	191.4705882	0	34	0	0.739562	FALSE	0	REST	55126	0.06821517
788359	taxon:9606	2.70568773	2.53E-04	177811	1902	syndecan 2	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0008218-&&-bioluminescence-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0008150-&&-biological_process-%%-GO:0048814-&&-regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005796-&&-Golgi lumen|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0005515-&&-protein binding	G:9606:SDC2			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05144-&&-Malaria	SDC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDC2	0.3695918	0.05241935	34	5	FALSE	SDC2	SDC2	87.78125	0	33	0	0.71571871	FALSE	1	SDC2	320742	0.04607688
788587	taxon:9606	2.45186702	5.42E-05	177389	1902	tubulin folding cofactor D	gene	biological_process-&-1&-GO:0034333-&&-adherens junction assembly-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0006457-&&-protein folding-%%-GO:0007023-&&-post-chaperonin tubulin folding pathway-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0007021-&&-tubulin complex assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion|cellular_component-&-1&-GO:0016328-&&-lateral plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005874-&&-microtubule-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TBCD				TBCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBCD	0.40785246	0.11586453	34	4	FALSE	TBCD	TBCD	199.8823529	0	34	0	0.75802216	FALSE	0	TBCD	92550	0.05755286
788629	taxon:9606	2.59177564	7.08E-04	177287	1902	transferrin	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0061024-&&-membrane organization-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0071281-&&-cellular response to iron ion-%%-GO:0002576-&&-platelet degranulation-%%-GO:0097460-&&-ferrous iron import into cell-%%-GO:0033572-&&-transferrin transport-%%-GO:0031647-&&-regulation of protein stability|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1990712-&&-HFE-transferrin receptor complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005770-&&-late endosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0045178-&&-basal part of cell-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0008199-&&-ferric iron binding-%%-GO:0015091-&&-ferric iron transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:1990459-&&-transferrin receptor binding	G:9606:TF			KEGG-&-1&-hsa04978-&&-Mineral absorption-%%-hsa04216-&&-Ferroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	TF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TF	0.38583587	0.06048387	34	4	FALSE	TF	TF	129.21875	0	33	0	0.73470406	FALSE	1	TF	728076	0.04982847
788668	taxon:9606	2.55144163	9.10E-05	177226	1902	thimet oligopeptidase 1	gene	biological_process-&-1&-GO:0006518-&&-peptide metabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:THOP1			KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa04614-&&-Renin-angiotensin system	THOP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THOP1	0.39193528	0.15329768	34	4	FALSE	THOP1	THOP1	140.5588235	0	34	0	0.7414264	FALSE	0	THOP1	108524	0.04912248
788685	taxon:9606	2.59555696	8.67E-05	177199	1902	toll like receptor 4	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032497-&&-detection of lipopolysaccharide-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0034128-&&-negative regulation of MyD88-independent toll-like receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0042116-&&-macrophage activation-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0070266-&&-necroptotic process-%%-GO:0016046-&&-detection of fungus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:1900227-&&-positive regulation of NLRP3 inflammasome complex assembly-%%-GO:0070430-&&-positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0050702-&&-interleukin-1 beta secretion-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010572-&&-positive regulation of platelet activation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0032727-&&-positive regulation of interferon-alpha production-%%-GO:0002537-&&-nitric oxide production involved in inflammatory response-%%-GO:0032609-&&-interferon-gamma production-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0002322-&&-B cell proliferation involved in immune response-%%-GO:0032707-&&-negative regulation of interleukin-23 production-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0014002-&&-astrocyte development-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0032732-&&-positive regulation of interleukin-1 production-%%-GO:0060729-&&-intestinal epithelial structure maintenance-%%-GO:0045359-&&-positive regulation of interferon-beta biosynthetic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070434-&&-positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0060907-&&-positive regulation of macrophage cytokine production-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0002730-&&-regulation of dendritic cell cytokine production-%%-GO:0071260-&&-cellular response to mechanical stimulus|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001875-&&-lipopolysaccharide receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0004872-&&-receptor activity	G:9606:TLR4			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05144-&&-Malaria-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	TLR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLR4	0.38527376	0.15524194	34	4	FALSE	TLR4	TLR4	146.96875	0	33	0	0.73407384	FALSE	1	TLR4	101616	0.05715989
788737	taxon:9606	2.68205451	2.94E-05	177067	1902	translin	gene	biological_process-&-1&-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0016070-&&-RNA metabolic process-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006310-&&-DNA recombination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:TSN				TSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSN	0.3728485	0.06854839	34	4	FALSE	TSN	TSN	122.9375	0	33	0	0.71965758	FALSE	1	TSN	51984	0.05928597
788758	taxon:9606	2.62375926	6.48E-05	176999	1902	polycomb group ring finger 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0016573-&&-histone acetylation|cellular_component-&-1&-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex-%%-GO:0001739-&&-sex chromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PCGF2			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PCGF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCGF2	0.38113253	0.16733871	34	4	FALSE	PCGF2	PCGF2	150.03125	0	33	0	0.72937346	FALSE	1	PCGF2	68816	0.06156314
788804	taxon:9606	2.82432645	5.61E-05	176842	1902	tubby like protein 3	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060348-&&-bone development-%%-GO:0060831-&&-smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0007420-&&-brain development-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:1903546-&&-protein localization to photoreceptor outer segment-%%-GO:0021953-&&-central nervous system neuron differentiation-%%-GO:0060434-&&-bronchus morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:1901621-&&-negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0021914-&&-negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning-%%-GO:0097500-&&-receptor localization to non-motile cilium-%%-GO:0001843-&&-neural tube closure-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0061548-&&-ganglion development-%%-GO:0031076-&&-embryonic camera-type eye development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005929-&&-cilium-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0030991-&&-intraciliary transport particle A-%%-GO:0005730-&&-nucleolus-%%-GO:0097546-&&-ciliary base-%%-GO:0005930-&&-axoneme|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:TULP3				TULP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TULP3	0.35406672	0.01960784	34	5	FALSE	TULP3	TULP3	56.29411765	0	34	0	0.69594559	FALSE	0	TULP3	54002	0.04475498
788881	taxon:9606	2.52056089	2.22E-05	176702	1902	WEE1 G2 checkpoint kinase	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0016301-&&-kinase activity	G:9606:WEE1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle	WEE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WEE1	0.39673709	0.17540323	34	4	FALSE	WEE1	WEE1	226.375	0	33	0	0.74657318	FALSE	1	WEE1	50986	0.0738961
789049	taxon:9606	2.53773436	1.06E-04	176295	1902	NSF attachment protein alpha	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0007420-&&-brain development-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0030182-&&-neuron differentiation-%%-GO:0045176-&&-apical protein localization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0010807-&&-regulation of synaptic vesicle priming-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0035494-&&-SNARE complex disassembly|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0005774-&&-vacuolar membrane-%%-GO:0043195-&&-terminal bouton-%%-GO:0016020-&&-membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0005829-&&-cytosol-%%-GO:0070044-&&-synaptobrevin 2-SNAP-25-syntaxin-1a complex|molecular_function-&-1&-GO:0005483-&&-soluble NSF attachment protein activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0019905-&&-syntaxin binding	G:9606:NAPA			KEGG-&-1&-hsa04721-&&-Synaptic vesicle cycle	NAPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAPA	0.39405228	0.16042781	34	4	FALSE	NAPA	NAPA	191.9117647	0	34	0	0.74371094	FALSE	0	NAPA	135096	0.06507902
789146	taxon:9606	2.5289113	2.26E-05	176114	1902	huntingtin interacting protein 1 related	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2000588-&&-positive regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0061024-&&-membrane organization-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0050821-&&-protein stabilization-%%-GO:1905445-&&-positive regulation of clathrin coat assembly-%%-GO:2000369-&&-regulation of clathrin-dependent endocytosis-%%-GO:0060453-&&-regulation of gastric acid secretion-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0034316-&&-negative regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0055123-&&-digestive system development-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:0072583-&&-clathrin-dependent endocytosis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0043197-&&-dendritic spine-%%-GO:0097060-&&-synaptic membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0032051-&&-clathrin light chain binding	G:9606:HIP1R				HIP1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIP1R	0.39542708	0.21774194	34	4	FALSE	HIP1R	HIP1R	232.5	0	33	0	0.74518145	FALSE	1	HIP1R	52308	0.0773092
789227	taxon:9606	2.50874429	6.35E-05	175963	1902	MAP kinase interacting serine/threonine kinase 1	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006417-&&-regulation of translation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity	G:9606:MKNK1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	MKNK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKNK1	0.39860579	0.09879032	34	4	FALSE	MKNK1	MKNK1	172.4375	0	33	0	0.74854262	FALSE	1	MKNK1	99676	0.0552792
789541	taxon:9606	2.7231763	2.95E-05	175228	1902	SET domain containing 1A	gene	biological_process-&-1&-GO:1902275-&&-regulation of chromatin organization-%%-GO:1902036-&&-regulation of hematopoietic stem cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051568-&&-histone H3-K4 methylation|cellular_component-&-1&-GO:0048188-&&-Set1C/COMPASS complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035097-&&-histone methyltransferase complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0003723-&&-RNA binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000166-&&-nucleotide binding	G:9606:SETD1A			KEGG-&-1&-hsa00310-&&-Lysine degradation	SETD1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETD1A	0.36721824	0.30659537	34	4	FALSE	SETD1A	SETD1A	204.8529412	0	34	0	0.71280395	FALSE	0	SETD1A	62926	0.1100452
789542	taxon:9606	2.86213959	1.37E-04	175230	1902	G protein-coupled receptor associated sorting protein 1	gene	biological_process-&-1&-GO:0008333-&&-endosome to lysosome transport-%%-GO:1990172-&&-G-protein coupled receptor catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GPRASP1				GPRASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPRASP1	0.34938897	0.01960784	34	4	FALSE	GPRASP1	GPRASP1	39.88235294	0	34	0	0.6896434	FALSE	0	GPRASP1	106310	0.03833314
789580	taxon:9606	2.85221364	2.91E-05	158755	1902	forkhead box I2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXI2				FOXI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXI2	0.35060487	0.01247772	34	4	FALSE	FOXI2	FOXI2	55.85294118	0	34	0	0.69129773	FALSE	0	FOXI2	41240	0.05156679
789775	taxon:9606	2.41752009	6.86E-05	174710	1902	solute carrier family 25 member 13	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0089712-&&-L-aspartate transmembrane transport-%%-GO:0043490-&&-malate-aspartate shuttle-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0045333-&&-cellular respiration-%%-GO:0015813-&&-L-glutamate transport-%%-GO:0051592-&&-response to calcium ion-%%-GO:0015810-&&-aspartate transport-%%-GO:0089711-&&-L-glutamate transmembrane transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005313-&&-L-glutamate transmembrane transporter activity-%%-GO:0015172-&&-acidic amino acid transmembrane transporter activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0015183-&&-L-aspartate transmembrane transporter activity-%%-GO:0005215-&&-transporter activity	G:9606:SLC25A13				SLC25A13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A13	0.41364703	0.09625668	34	4	FALSE	SLC25A13	SLC25A13	275.7941177	0	34	0	0.76374665	FALSE	0	SLC25A13	149662	0.07473795
789838	taxon:9606	2.61808729	1.56E-05	174537	1902	spindlin 1	gene	biological_process-&-1&-GO:0007276-&&-gamete generation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0009303-&&-rRNA transcription-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:SPIN1				SPIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPIN1	0.38195824	0.31550802	34	4	FALSE	SPIN1	SPIN1	257.9117647	0	34	0	0.73031879	FALSE	0	SPIN1	55204	0.10437009
789924	taxon:9606	2.55648338	1.94E-04	174347	1902	G protein subunit beta 5	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007165-&&-signal transduction-%%-GO:1901386-&&-negative regulation of voltage-gated calcium channel activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0031682-&&-G-protein gamma-subunit binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:GNB5			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNB5	0.39116233	0.06773619	34	4	FALSE	GNB5	GNB5	157.3823529	0	34	0	0.7405861	FALSE	0	GNB5	178650	0.05565515
790042	taxon:9606	2.62045061	2.88E-05	174030	1902	DnaJ heat shock protein family (Hsp40) member B4	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0006457-&&-protein folding-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJB4				DNAJB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB4	0.38161376	0.18716578	34	4	FALSE	DNAJB4	DNAJB4	159.1176471	0	34	0	0.7299249	FALSE	0	DNAJB4	51766	0.06514929
790138	taxon:9606	2.58563101	2.17E-05	173788	1902	hyaluronan binding protein 4	gene	biological_process-&-1&-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0030017-&&-sarcomere-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:HABP4				HABP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HABP4	0.38675279	0.12121212	34	4	FALSE	HABP4	HABP4	170.2352941	0	34	0	0.73572817	FALSE	0	HABP4	48116	0.0643035
790142	taxon:9606	2.6218686	6.10E-05	173786	1902	selenophosphate synthetase 1	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005525-&&-GTP binding-%%-GO:0004756-&&-selenide, water dikinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SEPHS1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00450-&&-Selenocompound metabolism	SEPHS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPHS1	0.38140737	0.07459677	34	4	FALSE	SEPHS1	SEPHS1	122.25	0	33	0	0.72968857	FALSE	1	SEPHS1	71842	0.04935807
790152	taxon:9606	2.57586261	8.39E-05	173753	1902	microtubule associated serine/threonine kinase 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:MAST1				MAST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAST1	0.38821946	0.21746881	34	4	FALSE	MAST1	MAST1	133.6470588	0	34	0	0.73735623	FALSE	0	MAST1	100270	0.04936742
790170	taxon:9606	2.73310225	1.10E-05	173717	1902	lysine demethylase 4B	gene	biological_process-&-1&-GO:0016577-&&-histone demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0051213-&&-dioxygenase activity-%%-GO:0032452-&&-histone demethylase activity	G:9606:KDM4B				KDM4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM4B	0.36588459	0.09447415	34	4	FALSE	KDM4B	KDM4B	193.6764706	0	34	0	0.71114962	FALSE	0	KDM4B	30964	0.10946696
790194	taxon:9606	2.5473452	3.22E-05	173679	1902	MYC binding protein 2, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding	G:9606:MYCBP2				MYCBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYCBP2	0.39256556	0.1372549	34	4	FALSE	MYCBP2	MYCBP2	202.6764706	0	34	0	0.74210913	FALSE	0	MYCBP2	68248	0.06989607
790269	taxon:9606	2.49109816	3.76E-05	173473	1902	non-SMC condensin I complex subunit H	gene	biological_process-&-1&-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0045132-&&-meiotic chromosome segregation-%%-GO:0010032-&&-meiotic chromosome condensation-%%-GO:0051301-&&-cell division|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000796-&&-condensin complex-%%-GO:0005829-&&-cytosol-%%-GO:0000799-&&-nuclear condensin complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0044547-&&-DNA topoisomerase binding-%%-GO:0005515-&&-protein binding-%%-GO:0072587-&&-DNA topoisomerase (ATP-hydrolyzing) activator activity	G:9606:NCAPH				NCAPH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPH	0.40142938	0.18360071	34	4	FALSE	NCAPH	NCAPH	211.1764706	0	34	0	0.75148364	FALSE	0	NCAPH	72762	0.06486853
790311	taxon:9606	2.71545612	4.00E-05	173353	1902	ubiquitin specific peptidase 49	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035616-&&-histone H2B conserved C-terminal lysine deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042393-&&-histone binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP49				USP49	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP49	0.36826226	0.04991087	34	4	FALSE	USP49	USP49	100.5882353	0	34	0	0.71409065	FALSE	0	USP49	50920	0.05364895
790637	taxon:9606	2.63825429	3.79E-05	155314	1902	zinc finger and BTB domain containing 8A	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003674-&&-molecular_function-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB8A				ZBTB8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB8A	0.37903852	0.09677419	34	4	FALSE	ZBTB8A	ZBTB8A	129.65625	0	33	0	0.72695762	FALSE	1	ZBTB8A	59426	0.05510953
790803	taxon:9606	2.68756893	1.03E-04	171162	1902	EGF containing fibulin like extracellular matrix protein 2	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005604-&&-basement membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:EFEMP2				EFEMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFEMP2	0.37208348	0.05645161	34	4	FALSE	EFEMP2	EFEMP2	92.4375	0	33	0	0.71873851	FALSE	1	EFEMP2	99870	0.04533862
790980	taxon:9606	2.66125729	3.09E-05	170523	1902	mediator complex subunit 9	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016592-&&-mediator complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED9				MED9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED9	0.37576224	0.52941176	34	5	FALSE	MED9	MED9	120.4705882	0	34	0	0.72312379	FALSE	0	MED9	47100	0.05438652
790991	taxon:9606	2.63904207	4.18E-05	170478	1902	RNA binding motif protein 23	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM23				RBM23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM23	0.37892537	0.06773619	34	4	FALSE	RBM23	RBM23	123.6176471	0	34	0	0.72682632	FALSE	0	RBM23	60130	0.05283784
791115	taxon:9606	2.56247046	4.74E-05	169996	1902	hemogen	gene	biological_process-&-1&-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:HEMGN				HEMGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEMGN	0.3902484	0.08199643	34	4	FALSE	HEMGN	HEMGN	161.6470588	0	34	0	0.73958826	FALSE	0	HEMGN	88448	0.05784349
791125	taxon:9606	2.59823539	2.72E-05	153569	1902	leucine zipper protein 6	gene		G:9606:LUZP6				LUZP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LUZP6	0.3848766	0.09982175	34	4	FALSE	LUZP6	LUZP6	159.7352941	0	34	0	0.73362744	FALSE	0	LUZP6	63282	0.06185356
791187	taxon:9606	2.78856153	3.55E-05	169791	1902	CNDP dipeptidase 2 (metallopeptidase M20 family)	gene	biological_process-&-1&-GO:0006750-&&-glutathione biosynthetic process-%%-GO:0000096-&&-sulfur amino acid metabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0102008-&&-cytosolic dipeptidase activity-%%-GO:0103046-&&-alanylglutamate dipeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0004180-&&-carboxypeptidase activity	G:9606:CNDP2			KEGG-&-1&-hsa00340-&&-Histidine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways	CNDP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNDP2	0.35860783	0.25806452	34	4	FALSE	CNDP2	CNDP2	78.65625	0	33	0	0.70190641	FALSE	1	CNDP2	39366	0.05590352
791389	taxon:9606	2.69859776	1.35E-05	168836	1902	lysine methyltransferase 2C	gene	biological_process-&-1&-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016746-&&-transferase activity, transferring acyl groups	G:9606:KMT2C			KEGG-&-1&-hsa00310-&&-Lysine degradation	KMT2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2C	0.37056282	0.28342246	34	4	FALSE	KMT2C	KMT2C	212.0588235	0	34	0	0.71690037	FALSE	0	KMT2C	43732	0.10591763
791421	taxon:9606	2.54797542	3.76E-05	168700	1902	mitochondrial ribosomal protein S5	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS5			KEGG-&-1&-hsa03010-&&-Ribosome	MRPS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS5	0.39246846	0.37433155	34	4	FALSE	MRPS5	MRPS5	202.8235294	0	34	0	0.7420041	FALSE	0	MRPS5	58086	0.06982256
791633	taxon:9606	2.4509217	5.50E-05	167723	1902	nucleoporin 85	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation|cellular_component-&-1&-GO:0031080-&&-nuclear pore outer ring-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000776-&&-kinetochore-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017056-&&-structural constituent of nuclear pore	G:9606:NUP85			KEGG-&-1&-hsa03013-&&-RNA transport	NUP85	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP85	0.40800977	0.17468806	34	4	FALSE	NUP85	NUP85	222.5294118	0	34	0	0.75817972	FALSE	0	NUP85	89772	0.06379014
791761	taxon:9606	2.65085867	3.70E-05	166968	1902	polycomb group ring finger 6	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0035102-&&-PRC1 complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:PCGF6			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PCGF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCGF6	0.37723626	0.17137097	34	5	FALSE	PCGF6	PCGF6	139.5	0	33	0	0.72485689	FALSE	1	PCGF6	55250	0.06025627
791791	taxon:9606	2.5738144	7.37E-05	166853	1902	inhibitor of growth family member 5	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006260-&&-DNA replication-%%-GO:0006473-&&-protein acetylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0045926-&&-negative regulation of growth-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070776-&&-MOZ/MORF histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:ING5				ING5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ING5	0.3885284	0.08199643	34	4	FALSE	ING5	ING5	147.8235294	0	34	0	0.7376976	FALSE	0	ING5	101724	0.05378947
792099	taxon:9606	2.6716559	3.11E-05	166227	1902	tripartite motif containing 15	gene	biological_process-&-1&-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1900246-&&-positive regulation of RIG-I signaling pathway-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1901253-&&-negative regulation of intracellular transport of viral material-%%-GO:0045087-&&-innate immune response-%%-GO:0007500-&&-mesodermal cell fate determination-%%-GO:0032481-&&-positive regulation of type I interferon production|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM15				TRIM15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM15	0.3742997	0.11693548	34	4	FALSE	TRIM15	TRIM15	121.59375	0	33	0	0.72139068	FALSE	1	TRIM15	48042	0.05704925
792143	taxon:9606	2.59697495	4.62E-05	166143	1902	zinc finger protein 622	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0033674-&&-positive regulation of kinase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF622				ZNF622	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF622	0.3850634	0.12096774	34	5	FALSE	ZNF622	ZNF622	146.59375	0	33	0	0.73383751	FALSE	1	ZNF622	65826	0.05662703
792182	taxon:9606	2.72333386	5.91E-05	182470	1902	ADP ribosylation factor 5	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:ARF5			KEGG-&-1&-hsa04144-&&-Endocytosis	ARF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF5	0.36719699	0.08734403	34	5	FALSE	ARF5	ARF5	92.58823529	0	34	0	0.71277769	FALSE	0	ARF5	68930	0.0505143
792430	taxon:9606	2.62423192	7.34E-05	182032	1902	cystatin B	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0008344-&&-adult locomotory behavior|cellular_component-&-1&-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0004866-&&-endopeptidase inhibitor activity	G:9606:CSTB				CSTB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTB	0.38106388	0.20320856	34	4	FALSE	CSTB	CSTB	237.6470588	0	34	0	0.72929468	FALSE	0	CSTB	115746	0.09725265
792524	taxon:9606	2.71514101	7.89E-05	181854	1902	calcium/calmodulin dependent protein kinase II beta	gene	biological_process-&-1&-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0051823-&&-regulation of synapse structural plasticity-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0090129-&&-positive regulation of synapse maturation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0014733-&&-regulation of skeletal muscle adaptation-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CAMK2B			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05152-&&-Tuberculosis-%%-hsa04740-&&-Olfactory transduction-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05214-&&-Glioma-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04360-&&-Axon guidance-%%-hsa04911-&&-Insulin secretion-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04713-&&-Circadian entrainment-%%-hsa04217-&&-Necroptosis	CAMK2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK2B	0.368305	0.05443548	34	4	FALSE	CAMK2B	CAMK2B	89.03125	0	33	0	0.71414316	FALSE	1	CAMK2B	81746	0.0472492
792538	taxon:9606	2.63620608	8.38E-05	181839	1902	calpastatin	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CAST				CAST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAST	0.37933301	0.114082	34	4	FALSE	CAST	CAST	144.7352941	0	34	0	0.72729899	FALSE	0	CAST	111990	0.06221671
792615	taxon:9606	2.55427761	5.09E-05	181715	1902	E2F transcription factor 6	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:E2F6				E2F6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F6	0.39150012	0.19607843	34	5	FALSE	E2F6	E2F6	173.7352941	0	34	0	0.74095373	FALSE	0	E2F6	85502	0.06057716
792942	taxon:9606	2.42145896	8.89E-05	181105	1902	phenylalanyl-tRNA synthetase alpha subunit	gene	biological_process-&-1&-GO:0006432-&&-phenylalanyl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0051290-&&-protein heterotetramerization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0009328-&&-phenylalanine-tRNA ligase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004826-&&-phenylalanine-tRNA ligase activity-%%-GO:0000049-&&-tRNA binding	G:9606:FARSA			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	FARSA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FARSA	0.41297417	0.14795009	34	4	FALSE	FARSA	FARSA	273.9117647	0	34	0	0.76309017	FALSE	0	FARSA	144558	0.07452208
792956	taxon:9606	2.52371199	1.24E-04	181084	1902	FGR proto-oncogene, Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050764-&&-regulation of phagocytosis-%%-GO:0030154-&&-cell differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0002768-&&-immune response-regulating cell surface receptor signaling pathway-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0009615-&&-response to virus-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0016477-&&-cell migration-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016235-&&-aggresome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0034988-&&-Fc-gamma receptor I complex binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0034987-&&-immunoglobulin receptor binding-%%-GO:0001784-&&-phosphotyrosine binding	G:9606:FGR			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway	FGR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGR	0.39624173	0.19354839	34	4	FALSE	FGR	FGR	187.40625	0	33	0	0.746048	FALSE	1	FGR	189196	0.06179891
793007	taxon:9606	2.59823539	2.72E-05	164571	1902	myotrophin	gene	biological_process-&-1&-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0030182-&&-neuron differentiation-%%-GO:0021707-&&-cerebellar granule cell differentiation-%%-GO:2000812-&&-regulation of barbed-end actin filament capping-%%-GO:0006584-&&-catecholamine metabolic process-%%-GO:0010557-&&-positive regulation of macromolecule biosynthetic process-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0006417-&&-regulation of translation-%%-GO:0016049-&&-cell growth-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding	G:9606:MTPN				MTPN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTPN	0.3848766	0.09982175	34	4	FALSE	MTPN	MTPN	159.7352941	0	34	0	0.73362744	FALSE	0	MTPN	63282	0.06185356
793150	taxon:9606	2.51662203	1.21E-04	180638	1902	glutamate dehydrogenase 1	gene	biological_process-&-1&-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0006538-&&-glutamate catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006537-&&-glutamate biosynthetic process-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0072350-&&-tricarboxylic acid metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0070728-&&-leucine binding-%%-GO:0004352-&&-glutamate dehydrogenase (NAD+) activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0004353-&&-glutamate dehydrogenase [NAD(P)+] activity-%%-GO:0005525-&&-GTP binding-%%-GO:0043531-&&-ADP binding	G:9606:GLUD1	GLUD1	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00471-&&-D-Glutamine and D-glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00910-&&-Nitrogen metabolism-%%-hsa04217-&&-Necroptosis	GLUD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLUD1	0.39735804	0.14516129	34	4	FALSE	GLUD1	GLUD1	250.34375	0	33	0	0.74722966	FALSE	1	GLUD1	163000	0.08101739
793153	taxon:9606	2.51662203	1.21E-04	180634	1902	glutamate dehydrogenase 1 pseudogene 5	gene		G:9606:GLUD1P5				GLUD1P5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLUD1P5	0.39735804	0.14516129	34	4	FALSE	GLUD1P5	GLUD1P5	250.34375	0	33	0	0.74722966	FALSE	1	GLUD1P5	163000	0.08101739
787040	taxon:9606	2.74539152	6.54E-05	180183	1902	homeobox B9	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0030879-&&-mammary gland development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXB9				HOXB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB9	0.36424677	0.04734848	33	4	FALSE	HOXB9	HOXB9	111.4242424	0	33	0	0.70910141	FALSE	0	HOXB9	92230	0.06498061
787259	taxon:9606	2.63652119	9.18E-05	179790	1902	inositol 1,4,5-trisphosphate receptor type 1	gene	biological_process-&-1&-GO:0050796-&&-regulation of insulin secretion-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0048016-&&-inositol phosphate-mediated signaling-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0007165-&&-signal transduction-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0006816-&&-calcium ion transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009791-&&-post-embryonic development-%%-GO:0050882-&&-voluntary musculoskeletal movement-%%-GO:0042045-&&-epithelial fluid transport-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0030168-&&-platelet activation-%%-GO:0050849-&&-negative regulation of calcium-mediated signaling|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005886-&&-plasma membrane-%%-GO:0031094-&&-platelet dense tubular network-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005955-&&-calcineurin complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0031088-&&-platelet dense granule membrane-%%-GO:0043234-&&-protein complex-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005637-&&-nuclear inner membrane|molecular_function-&-1&-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005220-&&-inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-%%-GO:0015085-&&-calcium ion transmembrane transporter activity-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0015278-&&-calcium-release channel activity	G:9606:ITPR1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04730-&&-Long-term depression-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04924-&&-Renin secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ITPR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITPR1	0.37928768	0.08333333	33	4	FALSE	ITPR1	ITPR1	120.5757576	0	33	0	0.72724647	FALSE	0	ITPR1	99734	0.05193312
787297	taxon:9606	2.71640145	6.46E-05	179715	1902	kinesin family member 5A	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007411-&&-axon guidance-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0008104-&&-protein localization-%%-GO:0098971-&&-anterograde dendritic transport of neurotransmitter receptor complex|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005871-&&-kinesin complex-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0043025-&&-neuronal cell body-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0035253-&&-ciliary rootlet|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0003774-&&-motor activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding	G:9606:KIF5A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse	KIF5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF5A	0.3681341	0.10322581	33	4	FALSE	KIF5A	KIF5A	99.41935484	0	32	0	0.71393309	FALSE	1	KIF5A	70620	0.05287025
787629	taxon:9606	2.52355444	1.37E-04	179060	1902	notch 3	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0072104-&&-glomerular capillary formation-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0019899-&&-enzyme binding	G:9606:NOTCH3	NOTCH3	TRUE	KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05165-&&-Human papillomavirus infection	NOTCH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH3	0.39626647	0.07575758	33	4	FALSE	NOTCH3	NOTCH3	160.6666667	0	33	0	0.74607426	FALSE	0	NOTCH3	139744	0.05297775
787677	taxon:9606	2.78288955	4.89E-04	178965	1902	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0072672-&&-neutrophil extravasation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:1903169-&&-regulation of calcium ion transmembrane transport-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0055118-&&-negative regulation of cardiac muscle contraction-%%-GO:2000270-&&-negative regulation of fibroblast apoptotic process-%%-GO:0035747-&&-natural killer cell chemotaxis-%%-GO:0042110-&&-T cell activation-%%-GO:0016310-&&-phosphorylation-%%-GO:0006954-&&-inflammatory response-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0042098-&&-T cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0097284-&&-hepatocyte apoptotic process-%%-GO:0002679-&&-respiratory burst involved in defense response-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0045087-&&-innate immune response-%%-GO:0030168-&&-platelet activation-%%-GO:0010897-&&-negative regulation of triglyceride catabolic process-%%-GO:0001816-&&-cytokine production-%%-GO:0070527-&&-platelet aggregation-%%-GO:0001525-&&-angiogenesis-%%-GO:0032252-&&-secretory granule localization-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0006897-&&-endocytosis-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0042629-&&-mast cell granule-%%-GO:0005944-&&-phosphatidylinositol 3-kinase complex, class IB|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PIK3CG	PIK3CG	TRUE	KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	PIK3CG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3CG	0.35933873	0.05113636	33	5	FALSE	PIK3CG	PIK3CG	72.81818182	0	33	0	0.70285174	FALSE	0	PIK3CG	530096	0.04952262
787704	taxon:9606	2.52103356	2.83E-05	178912	1902	procollagen-lysine,2-oxoglutarate 5-dioxygenase 1	gene	biological_process-&-1&-GO:0046947-&&-hydroxylysine biosynthetic process-%%-GO:0008544-&&-epidermis development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006464-&&-cellular protein modification process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030867-&&-rough endoplasmic reticulum membrane|molecular_function-&-1&-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0008475-&&-procollagen-lysine 5-dioxygenase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PLOD1	PLOD1	TRUE	KEGG-&-1&-hsa00310-&&-Lysine degradation	PLOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLOD1	0.39666271	0.21075269	33	4	FALSE	PLOD1	PLOD1	299.0322581	0	32	0	0.74649441	FALSE	1	PLOD1	72738	0.0975212
787768	taxon:9606	2.60768867	6.01E-05	178809	1902	periplakin	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001533-&&-cornified envelope-%%-GO:0030057-&&-desmosome-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PPL				PPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPL	0.38348136	0.07954545	33	4	FALSE	PPL	PPL	137.4545455	0	33	0	0.73205189	FALSE	0	PPL	80122	0.05476087
787770	taxon:9606	2.69245313	3.99E-05	178805	1902	protein phosphatase 2 regulatory subunit B'alpha	gene	biological_process-&-1&-GO:0090219-&&-negative regulation of lipid kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0090005-&&-negative regulation of establishment of protein localization to plasma membrane-%%-GO:0035307-&&-positive regulation of protein dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0016020-&&-membrane-%%-GO:0031430-&&-M band|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2R5A			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R5A	0.37140851	0.15340909	33	4	FALSE	PPP2R5A	PPP2R5A	110.0909091	0	33	0	0.71792448	FALSE	0	PPP2R5A	52666	0.05478088
787792	taxon:9606	2.81329762	9.05E-05	178778	1902	proteoglycan 2, pro eosinophil major basic protein	gene	biological_process-&-1&-GO:0042742-&&-defense response to bacterium-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0042035-&&-regulation of cytokine biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0002215-&&-defense response to nematode-%%-GO:0032753-&&-positive regulation of interleukin-4 production|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0030133-&&-transport vesicle-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0008201-&&-heparin binding	G:9606:PRG2			KEGG-&-1&-hsa05310-&&-Asthma	PRG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRG2	0.35545475	0.02651515	33	4	FALSE	PRG2	PRG2	58.06060606	0	33	0	0.69778373	FALSE	0	PRG2	90086	0.04624814
787960	taxon:9606	2.60784623	3.03E-05	162122	1902	NIMA related kinase 8	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0035330-&&-regulation of hippo signaling|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0097543-&&-ciliary inversin compartment-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0097546-&&-ciliary base|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:NEK8				NEK8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK8	0.38345819	0.14408602	33	4	FALSE	NEK8	NEK8	160.8709677	0	32	0	0.73202563	FALSE	1	NEK8	57642	0.06405346
787989	taxon:9606	2.73215692	2.44E-05	162062	1902	nephrocystin 4	gene	biological_process-&-1&-GO:0045494-&&-photoreceptor cell maintenance-%%-GO:0035845-&&-photoreceptor cell outer segment organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007632-&&-visual behavior-%%-GO:0035329-&&-hippo signaling-%%-GO:1903348-&&-positive regulation of bicellular tight junction assembly-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0007165-&&-signal transduction-%%-GO:0060041-&&-retina development in camera-type eye|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0036064-&&-ciliary basal body-%%-GO:0016020-&&-membrane-%%-GO:0005813-&&-centrosome-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0097470-&&-ribbon synapse-%%-GO:0097546-&&-ciliary base-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:NPHP4	NPHP4	TRUE		NPHP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPHP4	0.36601119	0.13333333	33	4	FALSE	NPHP4	NPHP4	124.7741936	0	32	0	0.71130718	FALSE	1	NPHP4	38634	0.07014359
788103	taxon:9606	2.6535371	2.15E-05	178239	1902	PHD finger protein 1	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding	G:9606:PHF1				PHF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF1	0.37685548	0.3655303	33	4	FALSE	PHF1	PHF1	243.7575758	0	33	0	0.72441048	FALSE	0	PHF1	55154	0.10729488
788144	taxon:9606	2.73688357	5.08E-05	178167	1902	glycogen phosphorylase, muscle associated	gene	biological_process-&-1&-GO:0005980-&&-glycogen catabolic process-%%-GO:0005977-&&-glycogen metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0008184-&&-glycogen phosphorylase activity	G:9606:PYGM	PYGM	TRUE	KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa04217-&&-Necroptosis	PYGM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYGM	0.36537908	0.03870968	33	4	FALSE	PYGM	PYGM	86.19354839	0	32	0	0.71051941	FALSE	1	PYGM	60622	0.04928573
788342	taxon:9606	2.73830156	5.44E-04	177837	1902	C-C motif chemokine ligand 5	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0009636-&&-response to toxic substance-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006887-&&-exocytosis-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0070233-&&-negative regulation of T cell apoptotic process-%%-GO:0009615-&&-response to virus-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0034112-&&-positive regulation of homotypic cell-cell adhesion-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0033634-&&-positive regulation of cell-cell adhesion mediated by integrin-%%-GO:0006816-&&-calcium ion transport-%%-GO:0070234-&&-positive regulation of T cell apoptotic process-%%-GO:0006935-&&-chemotaxis-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0070100-&&-negative regulation of chemokine-mediated signaling pathway-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0002676-&&-regulation of chronic inflammatory response-%%-GO:0042531-&&-positive regulation of tyrosine phosphorylation of STAT protein-%%-GO:0050863-&&-regulation of T cell activation-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010535-&&-positive regulation of activation of JAK2 kinase activity-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0051262-&&-protein tetramerization-%%-GO:0006954-&&-inflammatory response-%%-GO:0031328-&&-positive regulation of cellular biosynthetic process-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0042119-&&-neutrophil activation-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:2000110-&&-negative regulation of macrophage apoptotic process-%%-GO:0010759-&&-positive regulation of macrophage chemotaxis-%%-GO:2000503-&&-positive regulation of natural killer cell chemotaxis-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0048245-&&-eosinophil chemotaxis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0031726-&&-CCR1 chemokine receptor binding-%%-GO:0030298-&&-receptor signaling protein tyrosine kinase activator activity-%%-GO:0008009-&&-chemokine activity-%%-GO:0043621-&&-protein self-association-%%-GO:0031729-&&-CCR4 chemokine receptor binding-%%-GO:0042379-&&-chemokine receptor binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0016004-&&-phospholipase activator activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0046817-&&-chemokine receptor antagonist activity	G:9606:CCL5			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05323-&&-Rheumatoid arthritis	CCL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL5	0.36518987	0.02580645	33	5	FALSE	CCL5	CCL5	80.5483871	0	32	0	0.71028307	FALSE	1	CCL5	645344	0.04696729
788413	taxon:9606	2.69355601	9.94E-05	177719	1902	sulfotransferase family 1A member 1	gene	biological_process-&-1&-GO:0009308-&&-amine metabolic process-%%-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0008210-&&-estrogen metabolic process-%%-GO:0006584-&&-catecholamine metabolic process-%%-GO:0009812-&&-flavonoid metabolic process-%%-GO:0051923-&&-sulfation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0050294-&&-steroid sulfotransferase activity-%%-GO:0047894-&&-flavonol 3-sulfotransferase activity-%%-GO:0004062-&&-aryl sulfotransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008146-&&-sulfotransferase activity	G:9606:SULT1A1			KEGG-&-1&-hsa05204-&&-Chemical carcinogenesis	SULT1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SULT1A1	0.37125643	0.19886364	33	4	FALSE	SULT1A1	SULT1A1	98	0	33	0	0.71774066	FALSE	0	SULT1A1	107378	0.0487687
788605	taxon:9606	2.58846699	5.05E-05	177356	1902	transcription factor 20	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003677-&&-DNA binding	G:9606:TCF20				TCF20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF20	0.38632905	0.17204301	33	4	FALSE	TCF20	TCF20	191.4516129	0	32	0	0.7352555	FALSE	1	TCF20	69364	0.0719799
788752	taxon:9606	2.80116591	5.48E-05	160629	1902	transmembrane protein 173	gene	biological_process-&-1&-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0006915-&&-apoptotic process-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0045087-&&-innate immune response-%%-GO:0032479-&&-regulation of type I interferon production-%%-GO:0032608-&&-interferon-beta production-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051607-&&-defense response to virus-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061507-&&-cyclic-GMP-AMP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0035438-&&-cyclic-di-GMP binding	G:9606:TMEM173			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection	TMEM173	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM173	0.35699421	0.07526882	33	4	FALSE	TMEM173	TMEM173	65.70967742	0	32	0	0.69980568	FALSE	1	TMEM173	65670	0.04836324
788761	taxon:9606	2.49251615	6.79E-05	176994	1902	zinc finger and BTB domain containing 17	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0007398-&&-ectoderm development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB17			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	ZBTB17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB17	0.40120101	0.14193548	33	4	FALSE	ZBTB17	ZBTB17	205.0322581	0	32	0	0.75124731	FALSE	1	ZBTB17	95630	0.06293048
788844	taxon:9606	2.75074839	3.41E-05	176767	1902	ubiquinol-cytochrome c reductase binding protein	gene	biological_process-&-1&-GO:0006119-&&-oxidative phosphorylation-%%-GO:0006122-&&-mitochondrial electron transport, ubiquinol to cytochrome c-%%-GO:0034551-&&-mitochondrial respiratory chain complex III assembly-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:1902600-&&-hydrogen ion transmembrane transport-%%-GO:0009060-&&-aerobic respiration|cellular_component-&-1&-GO:0005746-&&-mitochondrial respiratory chain-%%-GO:0005750-&&-mitochondrial respiratory chain complex III-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008121-&&-ubiquinol-cytochrome-c reductase activity-%%-GO:0005515-&&-protein binding	G:9606:UQCRB			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	UQCRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UQCRB	0.36353743	0.21969697	33	4	FALSE	UQCRB	UQCRB	114.2121212	0	33	0	0.7082086	FALSE	0	UQCRB	45988	0.06831791
788946	taxon:9606	2.77075784	5.29E-05	176554	1902	FK506 binding protein 6	gene	biological_process-&-1&-GO:0007126-&&-meiotic nuclear division-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0006457-&&-protein folding-%%-GO:0030154-&&-cell differentiation-%%-GO:0034587-&&-piRNA metabolic process|cellular_component-&-1&-GO:0000795-&&-synaptonemal complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005515-&&-protein binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:FKBP6				FKBP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP6	0.36091209	0.04924242	33	4	FALSE	FKBP6	FKBP6	75.6969697	0	33	0	0.70487369	FALSE	0	FKBP6	53406	0.04843421
788976	taxon:9606	2.67732787	8.53E-06	160096	1902	lysine methyltransferase 5A	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0034770-&&-histone H4-K20 methylation-%%-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043516-&&-regulation of DNA damage response, signal transduction by p53 class mediator|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042799-&&-histone methyltransferase activity (H4-K20 specific)-%%-GO:0002039-&&-p53 binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0016278-&&-lysine N-methyltransferase activity	G:9606:KMT5A			KEGG-&-1&-hsa00310-&&-Lysine degradation	KMT5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT5A	0.37350674	0.30322581	33	4	FALSE	KMT5A	KMT5A	220.9354839	0	32	0	0.72044535	FALSE	1	KMT5A	26770	0.10371043
789316	taxon:9606	2.57412951	8.88E-05	175762	1902	mitogen-activated protein kinase 8 interacting protein 1	gene	biological_process-&-1&-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007258-&&-JUN phosphorylation-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0046328-&&-regulation of JNK cascade|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0044297-&&-cell body-%%-GO:0044295-&&-axonal growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0044302-&&-dentate gyrus mossy fiber-%%-GO:0044294-&&-dendritic growth cone-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0008432-&&-JUN kinase binding	G:9606:MAPK8IP1			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAPK8IP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8IP1	0.38848084	0.16129032	33	5	FALSE	MAPK8IP1	MAPK8IP1	138.6774194	0	32	0	0.73764508	FALSE	1	MAPK8IP1	93858	0.05101689
789363	taxon:9606	2.67055302	2.50E-05	175660	1902	SR-related CTD associated factor 11	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0006397-&&-mRNA processing-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:SCAF11				SCAF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAF11	0.37445428	0.15530303	33	5	FALSE	SCAF11	SCAF11	153.4242424	0	33	0	0.7215745	FALSE	0	SCAF11	50154	0.07093154
789450	taxon:9606	2.61257287	5.10E-05	175443	1902	vacuolar protein sorting 4 homolog B	gene	biological_process-&-1&-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:1903902-&&-positive regulation of viral life cycle-%%-GO:0090611-&&-ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0015031-&&-protein transport-%%-GO:0050792-&&-regulation of viral process-%%-GO:0019058-&&-viral life cycle-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0006997-&&-nucleus organization-%%-GO:0048524-&&-positive regulation of viral process-%%-GO:0061738-&&-late endosomal microautophagy-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0016197-&&-endosomal transport-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:1903542-&&-negative regulation of exosomal secretion-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0051261-&&-protein depolymerization-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0016236-&&-macroautophagy-%%-GO:1903724-&&-positive regulation of centriole elongation-%%-GO:0030301-&&-cholesterol transport-%%-GO:0007033-&&-vacuole organization-%%-GO:1904903-&&-ESCRT III complex disassembly-%%-GO:0033993-&&-response to lipid-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0032510-&&-endosome to lysosome transport via multivesicular body sorting pathway-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0019076-&&-viral release from host cell-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0090543-&&-Flemming body-%%-GO:0010008-&&-endosome membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008568-&&-microtubule-severing ATPase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0042623-&&-ATPase activity, coupled	G:9606:VPS4B			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	VPS4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS4B	0.38276444	0.11931818	33	4	FALSE	VPS4B	VPS4B	121.6969697	0	33	0	0.73123786	FALSE	0	VPS4B	69542	0.04886485
789512	taxon:9606	2.43138491	5.38E-05	175300	1902	pumilio RNA binding family member 1	gene	biological_process-&-1&-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0061157-&&-mRNA destabilization-%%-GO:0051983-&&-regulation of chromosome segregation-%%-GO:0060964-&&-regulation of gene silencing by miRNA-%%-GO:1900246-&&-positive regulation of RIG-I signaling pathway-%%-GO:2000637-&&-positive regulation of gene silencing by miRNA-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0016441-&&-posttranscriptional gene silencing-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0000932-&&-P-body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding	G:9606:PUM1				PUM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUM1	0.41128823	0.10795455	33	4	FALSE	PUM1	PUM1	276.5757576	0	33	0	0.76143585	FALSE	0	PUM1	113068	0.07619191
789522	taxon:9606	2.57428706	2.60E-05	175271	1902	phenylalanyl-tRNA synthetase beta subunit	gene	biological_process-&-1&-GO:0006432-&&-phenylalanyl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0009328-&&-phenylalanine-tRNA ligase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004826-&&-phenylalanine-tRNA ligase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:FARSB			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	FARSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FARSB	0.38845707	0.21022727	33	4	FALSE	FARSB	FARSB	196.5757576	0	33	0	0.73761882	FALSE	0	FARSB	48158	0.07235462
789613	taxon:9606	2.70521506	3.13E-05	175058	1902	nuclear receptor subfamily 1 group I member 3	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0030521-&&-androgen receptor signaling pathway|cellular_component-&-1&-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004882-&&-androgen receptor activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NR1I3	NR1I3	TRUE		NR1I3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR1I3	0.36965638	0.15913978	33	5	FALSE	NR1I3	NR1I3	118.3225807	0	32	0	0.71579749	FALSE	1	NR1I3	49480	0.06101706
789659	taxon:9606	2.64313849	3.77E-05	174958	1902	brain abundant membrane attached signal protein 1	gene	biological_process-&-1&-GO:0007356-&&-thorax and anterior abdomen determination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0072112-&&-glomerular visceral epithelial cell differentiation-%%-GO:0021762-&&-substantia nigra development-%%-GO:0060539-&&-diaphragm development-%%-GO:2001076-&&-positive regulation of metanephric ureteric bud development-%%-GO:0060421-&&-positive regulation of heart growth-%%-GO:0008406-&&-gonad development-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0072075-&&-metanephric mesenchyme development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0016607-&&-nuclear speck-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:BASP1				BASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BASP1	0.3783381	0.1969697	33	4	FALSE	BASP1	BASP1	156.1818182	0	33	0	0.72614358	FALSE	0	BASP1	55164	0.06761421
789742	taxon:9606	2.48369308	2.58E-05	158402	1902	olfactory receptor family 10 subfamily B member 1 pseudogene	gene		G:9606:OR10B1P				OR10B1P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OR10B1P	0.40262624	0.16477273	33	4	FALSE	OR10B1P	OR10B1P	220.8787879	0	33	0	0.75271782	FALSE	0	OR10B1P	84742	0.06699581
789868	taxon:9606	2.48369308	2.58E-05	174478	1902	ilvB acetolactate synthase like	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0016740-&&-transferase activity-%%-GO:0030976-&&-thiamine pyrophosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:ILVBL				ILVBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILVBL	0.40262624	0.16477273	33	4	FALSE	ILVBL	ILVBL	220.8787879	0	33	0	0.75271782	FALSE	0	ILVBL	84742	0.06699581
790057	taxon:9606	2.51126516	1.99E-05	173987	1902	PWP1 homolog, endonuclein	gene	biological_process-&-1&-GO:2000738-&&-positive regulation of stem cell differentiation-%%-GO:1903262-&&-negative regulation of serine phosphorylation of STAT3 protein-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034773-&&-histone H4-K20 trimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:1990889-&&-H4K20me3 modified histone binding	G:9606:PWP1				PWP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PWP1	0.39820566	0.3219697	33	4	FALSE	PWP1	PWP1	262.4545455	0	33	0	0.74812247	FALSE	0	PWP1	47378	0.08398324
790094	taxon:9606	2.49377659	2.99E-05	173891	1902	midasin AAA ATPase 1	gene	biological_process-&-1&-GO:0006461-&&-protein complex assembly-%%-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding	G:9606:MDN1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	MDN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDN1	0.40099823	0.125	33	4	FALSE	MDN1	MDN1	256.030303	0	33	0	0.75103724	FALSE	0	MDN1	78574	0.07968225
790157	taxon:9606	2.68914448	2.75E-05	173746	1902	lysine demethylase 2A	gene	biological_process-&-1&-GO:0070544-&&-histone H3-K36 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0032452-&&-histone demethylase activity	G:9606:KDM2A				KDM2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM2A	0.37186548	0.08333333	33	4	FALSE	KDM2A	KDM2A	131.8787879	0	33	0	0.71847592	FALSE	0	KDM2A	49144	0.0649372
790258	taxon:9606	2.58594612	4.65E-05	173495	1902	protein phosphatase 1 regulatory subunit 13B	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PPP1R13B				PPP1R13B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R13B	0.38670566	0.13068182	33	4	FALSE	PPP1R13B	PPP1R13B	154.8787879	0	33	0	0.73567565	FALSE	0	PPP1R13B	75640	0.05815768
790406	taxon:9606	2.68914448	1.22E-04	173102	1902	SH3 domain binding protein 4	gene	biological_process-&-1&-GO:0010508-&&-positive regulation of autophagy-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0061462-&&-protein localization to lysosome-%%-GO:0006897-&&-endocytosis-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0043090-&&-amino acid import-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0050790-&&-regulation of catalytic activity|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0005092-&&-GDP-dissociation inhibitor activity-%%-GO:0017016-&&-Ras GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SH3BP4				SH3BP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3BP4	0.37186548	0.07741935	33	4	FALSE	SH3BP4	SH3BP4	129.3870968	0	32	0	0.71847592	FALSE	1	SH3BP4	134670	0.06403562
790547	taxon:9606	2.52828108	3.47E-05	172530	1902	methionine adenosyltransferase 2B	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0006556-&&-S-adenosylmethionine biosynthetic process-%%-GO:0032259-&&-methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048269-&&-methionine adenosyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0048270-&&-methionine adenosyltransferase regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:MAT2B			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	MAT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAT2B	0.39552564	0.16666667	33	4	FALSE	MAT2B	MAT2B	165.3636364	0	33	0	0.74528649	FALSE	0	MAT2B	62064	0.05500111
790563	taxon:9606	2.52702064	5.95E-05	172128	1902	adaptor related protein complex 3 mu 1 subunit	gene	biological_process-&-1&-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0006622-&&-protein targeting to lysosome|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:AP3M1			KEGG-&-1&-hsa04142-&&-Lysosome	AP3M1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP3M1	0.39572293	0.14583333	33	4	FALSE	AP3M1	AP3M1	172.5454546	0	33	0	0.74549656	FALSE	0	AP3M1	89286	0.05680321
790573	taxon:9606	2.63463053	4.64E-05	172097	1902	linker for activation of T-cells	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0030168-&&-platelet activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0050863-&&-regulation of T cell activation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0002260-&&-lymphocyte homeostasis-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0042110-&&-T cell activation-%%-GO:0006955-&&-immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0010467-&&-gene expression|cellular_component-&-1&-GO:0008180-&&-COP9 signalosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0042629-&&-mast cell granule-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:LAT			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04660-&&-T cell receptor signaling pathway	LAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAT	0.37955986	0.28030303	33	4	FALSE	LAT	LAT	136.6969697	0	33	0	0.72756158	FALSE	0	LAT	67412	0.0589967
790683	taxon:9606	2.51930046	7.12E-05	171482	1902	formin homology 2 domain containing 1	gene	biological_process-&-1&-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0007097-&&-nuclear migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051660-&&-establishment of centrosome localization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001725-&&-stress fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032059-&&-bleb-%%-GO:0016020-&&-membrane-%%-GO:0014704-&&-intercalated disc|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:FHOD1				FHOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FHOD1	0.39693558	0.08387097	33	4	FALSE	FHOD1	FHOD1	190.8709677	0	32	0	0.74678326	FALSE	1	FHOD1	105682	0.0624643
790689	taxon:9606	2.716559	1.97E-05	171465	1902	B-cell linker	gene	biological_process-&-1&-GO:0006959-&&-humoral immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:BLNK			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05340-&&-Primary immunodeficiency	BLNK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLNK	0.36811275	0.28219697	33	4	FALSE	BLNK	BLNK	118.1818182	0	33	0	0.71390683	FALSE	0	BLNK	31716	0.06440633
790715	taxon:9606	2.82684733	4.42E-05	171400	1902	GDP-mannose pyrophosphorylase B	gene	biological_process-&-1&-GO:0009298-&&-GDP-mannose biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0004475-&&-mannose-1-phosphate guanylyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:GMPPB			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	GMPPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMPPB	0.35375098	0.04086022	33	5	FALSE	GMPPB	GMPPB	62.29032258	0	32	0	0.69552545	FALSE	1	GMPPB	44910	0.05113303
790744	taxon:9606	2.61761462	3.30E-05	171343	1902	ring finger protein, LIM domain interacting	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0060816-&&-random inactivation of X chromosome-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1900095-&&-regulation of dosage compensation by inactivation of X chromosome-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:RLIM				RLIM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RLIM	0.38202721	0.09247312	33	4	FALSE	RLIM	RLIM	147.8709677	0	32	0	0.73039756	FALSE	1	RLIM	56838	0.06020454
790812	taxon:9606	2.67606743	2.68E-05	171138	1902	deoxynucleotidyltransferase terminal interacting protein 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:DNTTIP2				DNTTIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNTTIP2	0.37368266	0.14393939	33	4	FALSE	DNTTIP2	DNTTIP2	217.6666667	0	33	0	0.72065543	FALSE	0	DNTTIP2	71506	0.10255311
790870	taxon:9606	2.65763353	3.09E-05	170821	1902	transmembrane and coiled-coil domains 1	gene	biological_process-&-1&-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0006983-&&-ER overload response-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005262-&&-calcium channel activity	G:9606:TMCO1	TMCO1	TRUE		TMCO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMCO1	0.3762746	0.19128788	33	4	FALSE	TMCO1	TMCO1	142.3939394	0	33	0	0.72372775	FALSE	0	TMCO1	60198	0.0641157
790944	taxon:9606	2.54246101	2.65E-05	170645	1902	cleavage and polyadenylation specific factor 3	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006398-&&-mRNA 3'-end processing by stem-loop binding and cleavage-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0006406-&&-mRNA export from nucleus|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008409-&&-5'-3' exonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004521-&&-endoribonuclease activity	G:9606:CPSF3			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CPSF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPSF3	0.3933197	0.22916667	33	4	FALSE	CPSF3	CPSF3	204.1818182	0	33	0	0.74292317	FALSE	0	CPSF3	53954	0.06925085
791018	taxon:9606	2.67323145	4.79E-05	170366	1902	zinc finger CCHC-type containing 10	gene	molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005515-&&-protein binding	G:9606:ZCCHC10				ZCCHC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZCCHC10	0.37407909	0.11742424	33	4	FALSE	ZCCHC10	ZCCHC10	116.9393939	0	33	0	0.72112809	FALSE	0	ZCCHC10	69534	0.0549474
791092	taxon:9606	2.45060659	3.29E-05	170078	1902	paraspeckle component 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0042382-&&-paraspeckles|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0001047-&&-core promoter binding	G:9606:PSPC1				PSPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSPC1	0.40806223	0.1780303	33	4	FALSE	PSPC1	PSPC1	291.6666667	0	33	0	0.75823224	FALSE	0	PSPC1	79644	0.08305499
791124	taxon:9606	2.58752166	3.43E-05	169958	1902	ring finger protein 114	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RNF114				RNF114	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF114	0.38647019	0.15913978	33	4	FALSE	RNF114	RNF114	188.8387097	0	32	0	0.73541306	FALSE	1	RNF114	62480	0.07116966
791171	taxon:9606	2.45170947	1.48E-04	169834	1902	Vac14, PIKFYVE complex component	gene	biological_process-&-1&-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070772-&&-PAS complex-%%-GO:0031901-&&-early endosome membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding	G:9606:VAC14			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05203-&&-Viral carcinogenesis	VAC14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAC14	0.40787867	0.04301075	33	4	FALSE	VAC14	VAC14	195.3548387	0	32	0	0.75804842	FALSE	1	VAC14	157994	0.05608726
791182	taxon:9606	2.520876	9.18E-05	169802	1902	DnaJ heat shock protein family (Hsp40) member C11	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DNAJC11				DNAJC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC11	0.3966875	0.07386364	33	4	FALSE	DNAJC11	DNAJC11	173.030303	0	33	0	0.74652067	FALSE	0	DNAJC11	126404	0.05653787
791295	taxon:9606	2.65227667	2.59E-05	169304	1902	ubiquitin specific peptidase 28	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0008283-&&-cell proliferation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0006281-&&-DNA repair-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0034644-&&-cellular response to UV|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP28				USP28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP28	0.37703457	0.15268817	33	4	FALSE	USP28	USP28	125.2903226	0	32	0	0.72462056	FALSE	1	USP28	41270	0.05587943
791315	taxon:9606	2.5240271	5.89E-05	169210	1902	coiled-coil domain containing 47	gene	biological_process-&-1&-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0009791-&&-post-embryonic development-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0006983-&&-ER overload response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CCDC47				CCDC47	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC47	0.39619226	0.10795455	33	4	FALSE	CCDC47	CCDC47	208.2424242	0	33	0	0.74599548	FALSE	0	CCDC47	127702	0.06844838
791374	taxon:9606	2.51551914	6.02E-05	168912	1902	tribbles pseudokinase 3	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0043405-&&-regulation of MAP kinase activity-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0055106-&&-ubiquitin-protein transferase regulator activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:TRIB3	TRIB3	TRUE	KEGG-&-1&-hsa04931-&&-Insulin resistance	TRIB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIB3	0.39753226	0.06818182	33	4	FALSE	TRIB3	TRIB3	176.030303	0	33	0	0.74741348	FALSE	0	TRIB3	91864	0.05719635
791404	taxon:9606	2.51441626	2.57E-05	168768	1902	RNA binding motif protein 15	gene	biological_process-&-1&-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0016032-&&-viral process-%%-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0048536-&&-spleen development-%%-GO:0060412-&&-ventricular septum morphogenesis|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding	G:9606:RBM15				RBM15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM15	0.39770662	0.16666667	33	4	FALSE	RBM15	RBM15	258.4242424	0	33	0	0.74759729	FALSE	0	RBM15	70446	0.08279915
791510	taxon:9606	2.70253663	1.06E-04	168340	1902	germ cell-less, spermatogenesis associated 1	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:GMCL1				GMCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMCL1	0.37002274	0.03655914	33	4	FALSE	GMCL1	GMCL1	90.4516129	0	32	0	0.71624389	FALSE	1	GMCL1	116348	0.04617526
791587	taxon:9606	2.75295415	1.60E-05	167917	1902	proteasomal ATPase associated factor 1	gene	biological_process-&-1&-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0000502-&&-proteasome complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PAAF1				PAAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAAF1	0.36324615	0.47727273	33	4	FALSE	PAAF1	PAAF1	117.3333333	0	33	0	0.70784097	FALSE	0	PAAF1	24462	0.07078641
791589	taxon:9606	2.65133134	4.12E-05	167915	1902	RUN and FYVE domain containing 1	gene	biological_process-&-1&-GO:0030100-&&-regulation of endocytosis-%%-GO:0006897-&&-endocytosis-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031901-&&-early endosome membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:RUFY1			KEGG-&-1&-hsa04144-&&-Endocytosis	RUFY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUFY1	0.377169	0.08387097	33	4	FALSE	RUFY1	RUFY1	108.0967742	0	32	0	0.72477811	FALSE	1	RUFY1	52342	0.04793528
791611	taxon:9606	2.58893966	4.41E-05	167823	1902	myosin heavy chain 14	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0019228-&&-neuronal action potential-%%-GO:0071625-&&-vocalization behavior-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0070584-&&-mitochondrion morphogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0097513-&&-myosin II filament-%%-GO:0016460-&&-myosin II complex-%%-GO:0030424-&&-axon-%%-GO:0016020-&&-membrane-%%-GO:0042641-&&-actomyosin-%%-GO:0005829-&&-cytosol-%%-GO:0005903-&&-brush border-%%-GO:0001725-&&-stress fiber-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030898-&&-actin-dependent ATPase activity	G:9606:MYH14			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYH14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH14	0.38625852	0.08522727	33	4	FALSE	MYH14	MYH14	170.8181818	0	33	0	0.73517672	FALSE	0	MYH14	71058	0.06500601
791632	taxon:9606	2.66188751	7.31E-05	167734	1902	Ras and Rab interactor 3	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0007165-&&-signal transduction-%%-GO:0006897-&&-endocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RIN3				RIN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIN3	0.37567328	0.08333333	33	4	FALSE	RIN3	RIN3	124.3333333	0	33	0	0.72301875	FALSE	0	RIN3	90800	0.0571058
791644	taxon:9606	2.80321412	4.82E-05	167602	1902	Yip1 domain family member 5	gene	biological_process-&-1&-GO:0060628-&&-regulation of ER to Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030134-&&-ER to Golgi transport vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:YIPF5				YIPF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YIPF5	0.35673336	0.14204545	33	4	FALSE	YIPF5	YIPF5	74.39393939	0	33	0	0.69946431	FALSE	0	YIPF5	52672	0.05552151
791722	taxon:9606	2.45958721	1.44E-05	167203	1902	LAS1 like, ribosome biogenesis factor	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:LAS1L				LAS1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAS1L	0.40657229	0.23106061	33	4	FALSE	LAS1L	LAS1L	331.0606061	0	33	0	0.75673547	FALSE	0	LAS1L	55168	0.0956735
791749	taxon:9606	2.59146053	2.53E-05	167075	1902	RNA binding motif protein 4B	gene	biological_process-&-1&-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0008380-&&-RNA splicing-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006417-&&-regulation of translation-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0006397-&&-mRNA processing-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:RBM4B				RBM4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM4B	0.38588278	0.14393939	33	4	FALSE	RBM4B	RBM4B	175.3636364	0	33	0	0.73475658	FALSE	0	RBM4B	47444	0.06664362
792080	taxon:9606	2.72254608	9.37E-05	182654	1902	ceroid-lipofuscinosis, neuronal 5	gene	biological_process-&-1&-GO:0070085-&&-glycosylation-%%-GO:0007042-&&-lysosomal lumen acidification-%%-GO:0022008-&&-neurogenesis-%%-GO:0030163-&&-protein catabolic process-%%-GO:0006465-&&-signal peptide processing-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0042551-&&-neuron maturation-%%-GO:1904426-&&-positive regulation of GTP binding-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005764-&&-lysosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0005515-&&-protein binding	G:9606:CLN5			KEGG-&-1&-hsa04142-&&-Lysosome	CLN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLN5	0.36730324	0.06439394	33	4	FALSE	CLN5	CLN5	88.93939394	0	33	0	0.71290899	FALSE	0	CLN5	106018	0.04916049
792103	taxon:9606	2.64975579	1.22E-04	182607	1902	collagen type I alpha 2 chain	gene	biological_process-&-1&-GO:0043589-&&-skin morphogenesis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030168-&&-platelet activation-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0001568-&&-blood vessel development-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0007596-&&-blood coagulation-%%-GO:0042476-&&-odontogenesis-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0050776-&&-regulation of immune response-%%-GO:0001501-&&-skeletal system development-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway|cellular_component-&-1&-GO:0005584-&&-collagen type I trimer-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0042802-&&-identical protein binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0046872-&&-metal ion binding	G:9606:COL1A2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04611-&&-Platelet activation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection	COL1A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL1A2	0.37739327	0.09090909	33	4	FALSE	COL1A2	COL1A2	103.1212121	0	33	0	0.7250407	FALSE	0	COL1A2	122214	0.04597561
792174	taxon:9606	2.40680637	2.71E-05	182478	1902	archain 1	gene	biological_process-&-1&-GO:0008344-&&-adult locomotory behavior-%%-GO:0021691-&&-cerebellar Purkinje cell layer maturation-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0043473-&&-pigmentation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0030126-&&-COPI vesicle coat|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:ARCN1				ARCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARCN1	0.41548835	0.26021505	33	4	FALSE	ARCN1	ARCN1	309.6451613	0	32	0	0.76553227	FALSE	1	ARCN1	76334	0.08201666
792249	taxon:9606	2.63415787	5.16E-05	182349	1902	ATPase H+ transporting V0 subunit a1	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0015986-&&-ATP synthesis coupled proton transport-%%-GO:0007035-&&-vacuolar acidification-%%-GO:0070072-&&-vacuolar proton-transporting V-type ATPase complex assembly-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:1901998-&&-toxin transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000220-&&-vacuolar proton-transporting V-type ATPase, V0 domain-%%-GO:0016607-&&-nuclear speck-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016471-&&-vacuolar proton-transporting V-type ATPase complex-%%-GO:0042470-&&-melanosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V0A1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V0A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V0A1	0.37962797	0.10795455	33	4	FALSE	ATP6V0A1	ATP6V0A1	122.4848485	0	33	0	0.72764036	FALSE	0	ATP6V0A1	76068	0.05167383
792271	taxon:9606	2.43894753	2.62E-05	182309	1902	cell division cycle 25C	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0007283-&&-spermatogenesis-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0016032-&&-viral process-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:CDC25C			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CDC25C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC25C	0.41001292	0.23484848	33	4	FALSE	CDC25C	CDC25C	260.1212121	0	33	0	0.76017541	FALSE	0	CDC25C	66204	0.07279343
792296	taxon:9606	2.66299039	1.00E-04	182273	1902	cyclin dependent kinase inhibitor 2C	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CDKN2C			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04934-&&-Cushing syndrome	CDKN2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN2C	0.37551769	0.05871212	33	4	FALSE	CDKN2C	CDKN2C	112.6363636	0	33	0	0.72283494	FALSE	0	CDKN2C	111554	0.05149018
792325	taxon:9606	2.70946904	5.35E-05	165837	1902	egl-9 family hypoxia inducible factor 3	gene	biological_process-&-1&-GO:0018126-&&-protein hydroxylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0031545-&&-peptidyl-proline 4-dioxygenase activity-%%-GO:0031418-&&-L-ascorbic acid binding	G:9606:EGLN3			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	EGLN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGLN3	0.369076	0.11612903	33	4	FALSE	EGLN3	EGLN3	100.6451613	0	32	0	0.71508849	FALSE	1	EGLN3	64372	0.05356283
792376	taxon:9606	2.43752954	4.42E-05	165747	1902	dermcidin	gene	biological_process-&-1&-GO:0042742-&&-defense response to bacterium-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006508-&&-proteolysis-%%-GO:0050832-&&-defense response to fungus-%%-GO:0031640-&&-killing of cells of other organism|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0008233-&&-peptidase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:DCD				DCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCD	0.41025144	0.16477273	33	4	FALSE	DCD	DCD	307.5757576	0	33	0	0.76041174	FALSE	0	DCD	94988	0.08610609
792380	taxon:9606	2.64928313	3.42E-05	182121	1902	carbamoyl-phosphate synthase 1	gene	biological_process-&-1&-GO:0014075-&&-response to amine-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0042311-&&-vasodilation-%%-GO:0046209-&&-nitric oxide metabolic process-%%-GO:0070409-&&-carbamoyl phosphate biosynthetic process-%%-GO:0006508-&&-proteolysis-%%-GO:0055081-&&-anion homeostasis-%%-GO:0019240-&&-citrulline biosynthetic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0010043-&&-response to zinc ion-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0042594-&&-response to starvation-%%-GO:0060416-&&-response to growth hormone-%%-GO:1903718-&&-cellular response to ammonia-%%-GO:0050667-&&-homocysteine metabolic process-%%-GO:0007494-&&-midgut development-%%-GO:0000050-&&-urea cycle-%%-GO:0043200-&&-response to amino acid-%%-GO:0042493-&&-response to drug-%%-GO:0071400-&&-cellular response to oleic acid-%%-GO:0032094-&&-response to food-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0019433-&&-triglyceride catabolic process|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0072341-&&-modified amino acid binding-%%-GO:0004087-&&-carbamoyl-phosphate synthase (ammonia) activity-%%-GO:0016595-&&-glutamate binding-%%-GO:0005515-&&-protein binding-%%-GO:0004088-&&-carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:CPS1			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00910-&&-Nitrogen metabolism	CPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPS1	0.3774606	0.12689394	33	4	FALSE	CPS1	CPS1	152.5757576	0	33	0	0.72511948	FALSE	0	CPS1	52086	0.06716927
792381	taxon:9606	2.53994013	5.29E-05	182120	1902	carnitine palmitoyltransferase 1A	gene	biological_process-&-1&-GO:0009437-&&-carnitine metabolic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0042755-&&-eating behavior-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042493-&&-response to drug-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation-%%-GO:0007623-&&-circadian rhythm|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0031307-&&-integral component of mitochondrial outer membrane|molecular_function-&-1&-GO:0004095-&&-carnitine O-palmitoyltransferase activity-%%-GO:1990698-&&-palmitoleoyltransferase activity-%%-GO:0042802-&&-identical protein binding	G:9606:CPT1A			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04931-&&-Insulin resistance-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	CPT1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPT1A	0.39371007	0.08712121	33	4	FALSE	CPT1A	CPT1A	182.5151515	0	33	0	0.74334331	FALSE	0	CPT1A	88912	0.06224071
792533	taxon:9606	2.48400819	2.88E-05	165462	1902	musashi RNA binding protein 2	gene	biological_process-&-1&-GO:0048864-&&-stem cell development|cellular_component-&-1&-GO:0005844-&&-polysome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MSI2			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	MSI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSI2	0.40257516	0.1969697	33	4	FALSE	MSI2	MSI2	272.7272727	0	33	0	0.7526653	FALSE	0	MSI2	79766	0.08293703
792541	taxon:9606	2.63573342	1.19E-04	181835	1902	caspase 2	gene	biological_process-&-1&-GO:0001554-&&-luteolysis-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007420-&&-brain development-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0007568-&&-aging-%%-GO:0003407-&&-neural retina development-%%-GO:0006915-&&-apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0016485-&&-protein processing-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0097194-&&-execution phase of apoptosis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis	G:9606:CASP2			KEGG-&-1&-hsa04210-&&-Apoptosis	CASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP2	0.37940104	0.14193548	33	4	FALSE	CASP2	CASP2	134.516129	0	32	0	0.72737776	FALSE	1	CASP2	144404	0.05741963
792559	taxon:9606	2.60359225	7.59E-05	181813	1902	core-binding factor beta subunit	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048469-&&-cell maturation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030098-&&-lymphocyte differentiation-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0030099-&&-myeloid cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:CBFB				CBFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBFB	0.38408472	0.06666667	33	4	FALSE	CBFB	CBFB	124.9032258	0	32	0	0.73273463	FALSE	1	CBFB	90546	0.0492991
792725	taxon:9606	2.55191429	6.34E-05	181495	1902	dihydrolipoamide S-acetyltransferase	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006086-&&-acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0030431-&&-sleep-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005967-&&-mitochondrial pyruvate dehydrogenase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0045254-&&-pyruvate dehydrogenase complex|molecular_function-&-1&-GO:0004742-&&-dihydrolipoyllysine-residue acetyltransferase activity-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0005515-&&-protein binding	G:9606:DLAT			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis	DLAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLAT	0.39186269	0.15530303	33	4	FALSE	DLAT	DLAT	176.1515152	0	33	0	0.74134762	FALSE	0	DLAT	95824	0.06134516
792771	taxon:9606	2.95415157	6.93E-04	181397	1902	dipeptidyl peptidase 4	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0006508-&&-proteolysis-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0033632-&&-regulation of cell-cell adhesion mediated by integrin-%%-GO:0036343-&&-psychomotor behavior-%%-GO:0010716-&&-negative regulation of extracellular matrix disassembly-%%-GO:0042110-&&-T cell activation-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0001666-&&-response to hypoxia-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0001662-&&-behavioral fear response-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0071438-&&-invadopodium membrane-%%-GO:0009986-&&-cell surface-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0016020-&&-membrane-%%-GO:0046581-&&-intercellular canaliculus-%%-GO:0045121-&&-membrane raft-%%-GO:0031258-&&-lamellipodium membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0008239-&&-dipeptidyl-peptidase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0001618-&&-virus receptor activity	G:9606:DPP4	DPP4	TRUE	KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	DPP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPP4	0.33850667	0.03870968	33	5	FALSE	DPP4	DPP4	23.35483871	0	32	0	0.67430807	FALSE	1	DPP4	745778	0.04222011
792875	taxon:9606	2.57428706	3.72E-05	181240	1902	ETS proto-oncogene 2, transcription factor	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0001501-&&-skeletal system development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007498-&&-mesoderm development-%%-GO:0001712-&&-ectodermal cell fate commitment-%%-GO:0090009-&&-primitive streak formation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035259-&&-glucocorticoid receptor binding	G:9606:ETS2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	ETS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETS2	0.38845707	0.20215054	33	4	FALSE	ETS2	ETS2	189.5483871	0	32	0	0.73761882	FALSE	1	ETS2	67232	0.0692558
792960	taxon:9606	2.75783835	1.77E-05	164702	1902	sulfiredoxin 1	gene	biological_process-&-1&-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006979-&&-response to oxidative stress|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016667-&&-oxidoreductase activity, acting on a sulfur group of donors-%%-GO:0032542-&&-sulfiredoxin activity	G:9606:SRXN1				SRXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRXN1	0.36260283	0.19318182	33	4	FALSE	SRXN1	SRXN1	92.90909091	0	33	0	0.70702694	FALSE	0	SRXN1	31104	0.05752885
793026	taxon:9606	2.82038758	6.65E-05	180872	1902	glutamate ionotropic receptor AMPA type subunit 2	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030666-&&-endocytic vesicle membrane|molecular_function-&-1&-GO:0004971-&&-AMPA glutamate receptor activity-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0004970-&&-ionotropic glutamate receptor activity-%%-GO:0005231-&&-excitatory extracellular ligand-gated ion channel activity-%%-GO:0005515-&&-protein binding	G:9606:GRIA2	GRIA2	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05030-&&-Cocaine addiction-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05031-&&-Amphetamine addiction	GRIA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIA2	0.3545612	0.0530303	33	4	FALSE	GRIA2	GRIA2	56.15151515	0	33	0	0.69660207	FALSE	0	GRIA2	56212	0.0459546
793192	taxon:9606	2.58232236	2.01E-05	180555	1902	hypoxanthine phosphoribosyltransferase 1	gene	biological_process-&-1&-GO:0006166-&&-purine ribonucleoside salvage-%%-GO:0046038-&&-GMP catabolic process-%%-GO:0045964-&&-positive regulation of dopamine metabolic process-%%-GO:0046100-&&-hypoxanthine metabolic process-%%-GO:0006164-&&-purine nucleotide biosynthetic process-%%-GO:0021756-&&-striatum development-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0006178-&&-guanine salvage-%%-GO:0001975-&&-response to amphetamine-%%-GO:0046651-&&-lymphocyte proliferation-%%-GO:0043103-&&-hypoxanthine salvage-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0046040-&&-IMP metabolic process-%%-GO:0019835-&&-cytolysis-%%-GO:0006168-&&-adenine salvage-%%-GO:0007626-&&-locomotory behavior-%%-GO:0021895-&&-cerebral cortex neuron differentiation-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:0043101-&&-purine-containing compound salvage-%%-GO:0032264-&&-IMP salvage-%%-GO:0007625-&&-grooming behavior|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0004422-&&-hypoxanthine phosphoribosyltransferase activity-%%-GO:0052657-&&-guanine phosphoribosyltransferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:HPRT1			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	HPRT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPRT1	0.38724832	0.12043011	33	4	FALSE	HPRT1	HPRT1	214.8064516	0	32	0	0.73627961	FALSE	1	HPRT1	52302	0.07995435
793269	taxon:9606	2.67622499	3.12E-05	164012	1902	toll like receptor adaptor molecule 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0034128-&&-negative regulation of MyD88-independent toll-like receptor signaling pathway-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0070266-&&-necroptotic process-%%-GO:0032816-&&-positive regulation of natural killer cell activation-%%-GO:0045359-&&-positive regulation of interferon-beta biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0051607-&&-defense response to virus-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005776-&&-autophagosome-%%-GO:0097342-&&-ripoptosome-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding	G:9606:TICAM1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	TICAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TICAM1	0.37366066	0.19354839	33	4	FALSE	TICAM1	TICAM1	118.6129032	0	32	0	0.72062917	FALSE	1	TICAM1	47816	0.05686587
787038	taxon:9606	2.75894123	5.91E-05	180187	1902	homeobox B5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045446-&&-endothelial cell differentiation-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:HOXB5				HOXB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB5	0.36245788	0.03024194	32	5	FALSE	HOXB5	HOXB5	80.90625	0	32	0	0.70684313	FALSE	0	HOXB5	68326	0.05084545
787241	taxon:9606	2.84512368	1.83E-04	163425	1902	spectrin repeat containing nuclear envelope family member 4	gene	biological_process-&-1&-GO:0045198-&&-establishment of epithelial cell apical/basal polarity|cellular_component-&-1&-GO:0031309-&&-integral component of nuclear outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SYNE4				SYNE4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNE4	0.35147857	0.0483871	32	4	FALSE	SYNE4	SYNE4	48.40625	0	32	0	0.69247939	FALSE	0	SYNE4	196800	0.04412442
787273	taxon:9606	2.62927367	5.44E-05	179767	1902	potassium voltage-gated channel subfamily A member 5	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0086052-&&-membrane repolarization during SA node cell action potential-%%-GO:2000288-&&-positive regulation of myoblast proliferation-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0086014-&&-atrial cardiac muscle cell action potential-%%-GO:0006813-&&-potassium ion transport-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0043266-&&-regulation of potassium ion transport-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0010033-&&-response to organic substance-%%-GO:0071435-&&-potassium ion export-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0098914-&&-membrane repolarization during atrial cardiac muscle cell action potential-%%-GO:0060372-&&-regulation of atrial cardiac muscle cell membrane repolarization-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0055075-&&-potassium ion homeostasis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0086050-&&-membrane repolarization during bundle of His cell action potential-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0009612-&&-response to mechanical stimulus|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030018-&&-Z disc-%%-GO:0014704-&&-intercalated disc-%%-GO:0034705-&&-potassium channel complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005901-&&-caveola-%%-GO:0046691-&&-intracellular canaliculus-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0086090-&&-voltage-gated potassium channel activity involved in SA node cell action potential repolarization-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0015271-&&-outward rectifier potassium channel activity-%%-GO:0086087-&&-voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization-%%-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0086089-&&-voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	G:9606:KCNA5				KCNA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNA5	0.38033317	0.09655172	32	4	FALSE	KCNA5	KCNA5	147.1	0	31	0	0.72845439	FALSE	1	KCNA5	73752	0.06152022
787328	taxon:9606	2.51520403	3.99E-05	179657	1902	keratin 17	gene	biological_process-&-1&-GO:0045109-&&-intermediate filament organization-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0008544-&&-epidermis development-%%-GO:0007165-&&-signal transduction-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0051798-&&-positive regulation of hair follicle development|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0042289-&&-MHC class II protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0032395-&&-MHC class II receptor activity	G:9606:KRT17			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT17	0.39758206	0.20766129	32	4	FALSE	KRT17	KRT17	221.3125	0	32	0	0.74746599	FALSE	0	KRT17	65348	0.0717878
787420	taxon:9606	2.55475028	2.08E-05	163082	1902	CREB regulated transcription coactivator 2	gene	biological_process-&-1&-GO:0043970-&&-histone H3-K9 acetylation-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1901998-&&-toxin transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008140-&&-cAMP response element binding protein binding	G:9606:CRTC2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04931-&&-Insulin resistance	CRTC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRTC2	0.39142769	0.29032258	32	4	FALSE	CRTC2	CRTC2	293	0	32	0	0.74087495	FALSE	0	CRTC2	60508	0.10232929
787448	taxon:9606	2.62391681	2.98E-05	179412	1902	myocyte enhancer factor 2C	gene	biological_process-&-1&-GO:0003138-&&-primary heart field specification-%%-GO:0030220-&&-platelet formation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0006915-&&-apoptotic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0001947-&&-heart looping-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060025-&&-regulation of synaptic activity-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0007399-&&-nervous system development-%%-GO:0042100-&&-B cell proliferation-%%-GO:2001016-&&-positive regulation of skeletal muscle cell differentiation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0072160-&&-nephron tubule epithelial cell differentiation-%%-GO:0045652-&&-regulation of megakaryocyte differentiation-%%-GO:0021542-&&-dentate gyrus development-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0001958-&&-endochondral ossification-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0007517-&&-muscle organ development-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0001568-&&-blood vessel development-%%-GO:0001764-&&-neuron migration-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0060290-&&-transdifferentiation-%%-GO:0033197-&&-response to vitamin E-%%-GO:0035984-&&-cellular response to trichostatin A-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0060297-&&-regulation of sarcomere organization-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0060021-&&-palate development-%%-GO:0006959-&&-humoral immune response-%%-GO:0007507-&&-heart development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:2000987-&&-positive regulation of behavioral fear response-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0072102-&&-glomerulus morphogenesis-%%-GO:0071864-&&-positive regulation of cell proliferation in bone marrow-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0048666-&&-neuron development-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0002467-&&-germinal center formation-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0014902-&&-myotube differentiation-%%-GO:0003185-&&-sinoatrial valve morphogenesis-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0046928-&&-regulation of neurotransmitter secretion-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0003211-&&-cardiac ventricle formation-%%-GO:2001013-&&-epithelial cell proliferation involved in renal tubule morphogenesis-%%-GO:0048703-&&-embryonic viscerocranium morphogenesis-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051963-&&-regulation of synapse assembly-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0007611-&&-learning or memory-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0090073-&&-positive regulation of protein homodimerization activity-%%-GO:0061333-&&-renal tubule morphogenesis-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:2000111-&&-positive regulation of macrophage apoptotic process-%%-GO:0002634-&&-regulation of germinal center formation-%%-GO:0007521-&&-muscle cell fate determination-%%-GO:0009615-&&-response to virus-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0014033-&&-neural crest cell differentiation|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0098794-&&-postsynapse-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0003680-&&-AT DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0033613-&&-activating transcription factor binding	G:9606:MEF2C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MEF2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEF2C	0.38110964	0.19310345	32	4	FALSE	MEF2C	MEF2C	165.2666667	0	31	0	0.7293472	FALSE	1	MEF2C	48110	0.06780194
787627	taxon:9606	2.66236017	4.03E-05	179066	1902	CCR4-NOT transcription complex subunit 2	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0010606-&&-positive regulation of cytoplasmic mRNA processing body assembly-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000932-&&-P-body-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030015-&&-CCR4-NOT core complex-%%-GO:0005829-&&-cytosol-%%-GO:0030014-&&-CCR4-NOT complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001226-&&-RNA polymerase II transcription corepressor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity	G:9606:CNOT2			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT2	0.37560658	0.11693548	32	4	FALSE	CNOT2	CNOT2	122.25	0	32	0	0.72293997	FALSE	0	CNOT2	55860	0.05604635
787635	taxon:9606	2.56136758	2.82E-05	179055	1902	purine nucleoside phosphorylase	gene	biological_process-&-1&-GO:0034418-&&-urate biosynthetic process-%%-GO:0006148-&&-inosine catabolic process-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0006195-&&-purine nucleotide catabolic process-%%-GO:0006738-&&-nicotinamide riboside catabolic process-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0070970-&&-interleukin-2 secretion-%%-GO:0006955-&&-immune response-%%-GO:0042493-&&-response to drug-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0043101-&&-purine-containing compound salvage|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0042301-&&-phosphate ion binding-%%-GO:0004731-&&-purine-nucleoside phosphorylase activity-%%-GO:0002060-&&-purine nucleobase binding-%%-GO:0001882-&&-nucleoside binding	G:9606:PNP			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	PNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNP	0.39041644	0.10804598	32	4	FALSE	PNP	PNP	208.5333333	0	31	0	0.73977207	FALSE	1	PNP	61750	0.07357092
787686	taxon:9606	2.64707736	3.00E-05	178951	1902	polycystin 1, transient receptor potential channel interacting	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0021915-&&-neural tube development-%%-GO:0072164-&&-mesonephric tubule development-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0072287-&&-metanephric distal tubule morphogenesis-%%-GO:0036303-&&-lymph vessel morphogenesis-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0048565-&&-digestive tract development-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0001889-&&-liver development-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0048806-&&-genitalia development-%%-GO:0060236-&&-regulation of mitotic spindle organization-%%-GO:0060428-&&-lung epithelium development-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0001822-&&-kidney development-%%-GO:0001502-&&-cartilage condensation-%%-GO:0072218-&&-metanephric ascending thin limb development-%%-GO:0072205-&&-metanephric collecting duct development-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0072177-&&-mesonephric duct development-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0051216-&&-cartilage development-%%-GO:0007161-&&-calcium-independent cell-matrix adhesion-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0021510-&&-spinal cord development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0072237-&&-metanephric proximal tubule development-%%-GO:0006807-&&-nitrogen compound metabolic process-%%-GO:0043588-&&-skin development-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0005929-&&-cilium-%%-GO:0031514-&&-motile cilium-%%-GO:0002133-&&-polycystin complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005262-&&-calcium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0044325-&&-ion channel binding	G:9606:PKD1	PKD1	TRUE		PKD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKD1	0.37777513	0.14942529	32	4	FALSE	PKD1	PKD1	142.3333333	0	31	0	0.72548711	FALSE	1	PKD1	46540	0.06335413
787689	taxon:9606	2.68741138	3.80E-05	178940	1902	phospholipase A2 group IVA	gene	biological_process-&-1&-GO:0035965-&&-cardiolipin acyl-chain remodeling-%%-GO:0036152-&&-phosphatidylethanolamine acyl-chain remodeling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006690-&&-icosanoid metabolic process-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0036151-&&-phosphatidylcholine acyl-chain remodeling-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0036148-&&-phosphatidylglycerol acyl-chain remodeling-%%-GO:0036149-&&-phosphatidylinositol acyl-chain remodeling-%%-GO:0006663-&&-platelet activating factor biosynthetic process-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0046456-&&-icosanoid biosynthetic process-%%-GO:0036150-&&-phosphatidylserine acyl-chain remodeling-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0071236-&&-cellular response to antibiotic|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0004623-&&-phospholipase A2 activity-%%-GO:0008970-&&-phosphatidylcholine 1-acylhydrolase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0004622-&&-lysophospholipase activity-%%-GO:0047498-&&-calcium-dependent phospholipase A2 activity	G:9606:PLA2G4A			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa04726-&&-Serotonergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04730-&&-Long-term depression-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa04217-&&-Necroptosis	PLA2G4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLA2G4A	0.37210529	0.09195402	32	4	FALSE	PLA2G4A	PLA2G4A	117.5666667	0	31	0	0.71876477	FALSE	1	PLA2G4A	56890	0.05827541
788061	taxon:9606	2.75972901	3.30E-05	161909	1902	forkhead box R1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXR1				FOXR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXR1	0.36235442	0.20766129	32	4	FALSE	FOXR1	FOXR1	85.5625	0	32	0	0.70671183	FALSE	0	FOXR1	39968	0.05290248
788149	taxon:9606	2.65306444	8.97E-05	178157	1902	RAB4A, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0032482-&&-Rab protein signal transduction-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0019882-&&-antigen processing and presentation|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0032593-&&-insulin-responsive compartment-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0098837-&&-postsynaptic recycling endosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0019003-&&-GDP binding-%%-GO:0001671-&&-ATPase activator activity	G:9606:RAB4A			KEGG-&-1&-hsa04144-&&-Endocytosis	RAB4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB4A	0.37692262	0.0625	32	4	FALSE	RAB4A	RAB4A	103	0	32	0	0.72448926	FALSE	0	RAB4A	83894	0.04612427
788406	taxon:9606	2.716559	4.12E-05	177725	1902	syntaxin 4	gene	biological_process-&-1&-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0048278-&&-vesicle docking-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0033194-&&-response to hydroperoxide-%%-GO:1990668-&&-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0043311-&&-positive regulation of eosinophil degranulation-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0051024-&&-positive regulation of immunoglobulin secretion-%%-GO:0035493-&&-SNARE complex assembly-%%-GO:0048284-&&-organelle fusion-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045785-&&-positive regulation of cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042581-&&-specific granule-%%-GO:0036477-&&-somatodendritic compartment-%%-GO:0005829-&&-cytosol-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030027-&&-lamellipodium-%%-GO:0031201-&&-SNARE complex-%%-GO:0009986-&&-cell surface-%%-GO:0043219-&&-lateral loop-%%-GO:0035749-&&-myelin sheath adaxonal region-%%-GO:0005773-&&-vacuole-%%-GO:0000322-&&-storage vacuole-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0045202-&&-synapse-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005622-&&-intracellular-%%-GO:0005768-&&-endosome-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0016230-&&-sphingomyelin phosphodiesterase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding	G:9606:STX4			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04962-&&-Vasopressin-regulated water reabsorption	STX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX4	0.36811275	0.12183908	32	4	FALSE	STX4	STX4	99.56666667	0	31	0	0.71390683	FALSE	1	STX4	49594	0.05364977
788425	taxon:9606	2.77012762	3.98E-05	177694	1902	secreted frizzled related protein 4	gene	biological_process-&-1&-GO:0060349-&&-bone morphogenesis-%%-GO:2000119-&&-negative regulation of sodium-dependent phosphate transport-%%-GO:0009725-&&-response to hormone-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0030510-&&-regulation of BMP signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045606-&&-positive regulation of epidermal cell differentiation-%%-GO:0055062-&&-phosphate ion homeostasis-%%-GO:0030154-&&-cell differentiation-%%-GO:2000051-&&-negative regulation of non-canonical Wnt signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1902174-&&-positive regulation of keratinocyte apoptotic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0017147-&&-Wnt-protein binding-%%-GO:0005515-&&-protein binding	G:9606:SFRP4			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	SFRP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFRP4	0.3609942	0.03629032	32	5	FALSE	SFRP4	SFRP4	78.6875	0	32	0	0.70497873	FALSE	0	SFRP4	47524	0.05080658
789063	taxon:9606	2.66141484	4.54E-05	176262	1902	cyclin K	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:2001165-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071157-&&-negative regulation of cell cycle arrest|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0002944-&&-cyclin K-CDK12 complex-%%-GO:0002945-&&-cyclin K-CDK13 complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:CCNK				CCNK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNK	0.37574	0.08870968	32	4	FALSE	CCNK	CCNK	121.625	0	32	0	0.72309753	FALSE	0	CCNK	67044	0.05472623
789133	taxon:9606	2.651804	3.81E-05	176142	1902	ubiquitin specific peptidase 13 (isopeptidase T-3)	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050821-&&-protein stabilization-%%-GO:0035523-&&-protein K29-linked deubiquitination-%%-GO:1904378-&&-maintenance of unfolded protein involved in ERAD pathway-%%-GO:0044313-&&-protein K6-linked deubiquitination-%%-GO:0006914-&&-autophagy-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:1904294-&&-positive regulation of ERAD pathway-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:1904454-&&-ubiquitin-specific protease activity involved in positive regulation of ERAD pathway-%%-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding-%%-GO:1904288-&&-BAT3 complex binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0044389-&&-ubiquitin-like protein ligase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP13				USP13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP13	0.37710178	0.12903226	32	4	FALSE	USP13	USP13	126.875	0	32	0	0.72469933	FALSE	0	USP13	53046	0.05692916
789148	taxon:9606	2.59130298	5.04E-05	176106	1902	SH2 domain containing 2A	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:SH2D2A			KEGG-&-1&-hsa04370-&&-VEGF signaling pathway	SH2D2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D2A	0.38590624	0.2358871	32	4	FALSE	SH2D2A	SH2D2A	164.46875	0	32	0	0.73478284	FALSE	0	SH2D2A	73578	0.06285851
789349	taxon:9606	2.52056089	6.87E-05	175684	1902	Rho guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARHGEF1			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05163-&&-Human cytomegalovirus infection	ARHGEF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF1	0.39673709	0.07356322	32	4	FALSE	ARHGEF1	ARHGEF1	201.4	0	31	0	0.74657318	FALSE	1	ARHGEF1	97920	0.06578374
789439	taxon:9606	2.61225776	3.35E-05	175471	1902	zinc finger FYVE-type containing 9	gene	biological_process-&-1&-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0007183-&&-SMAD protein complex assembly-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding	G:9606:ZFYVE9			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04350-&&-TGF-beta signaling pathway	ZFYVE9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFYVE9	0.38281062	0.12298387	32	4	FALSE	ZFYVE9	ZFYVE9	149.4375	0	32	0	0.73129037	FALSE	0	ZFYVE9	53148	0.0600362
789722	taxon:9606	2.47707578	8.07E-05	174826	1902	mitochondrial ribosomal protein L28	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:MRPL28			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL28	0.40370182	0.21975806	32	4	FALSE	MRPL28	MRPL28	213.15625	0	32	0	0.7538207	FALSE	0	MRPL28	116138	0.06394433
789978	taxon:9606	2.62769813	4.75E-05	174200	1902	related RAS viral (r-ras) oncogene homolog 2	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:RRAS2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal	RRAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRAS2	0.38056122	0.07459677	32	4	FALSE	RRAS2	RRAS2	136.15625	0	32	0	0.72871698	FALSE	0	RRAS2	70364	0.05700996
790015	taxon:9606	2.68347251	2.22E-05	174093	1902	Snf2 related CREBBP activator protein	gene	biological_process-&-1&-GO:0016573-&&-histone acetylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0043234-&&-protein complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:SRCAP				SRCAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRCAP	0.37265148	0.18346774	32	4	FALSE	SRCAP	SRCAP	150.59375	0	32	0	0.71942125	FALSE	0	SRCAP	45020	0.07246028
790047	taxon:9606	2.56703955	5.18E-05	174011	1902	katanin catalytic subunit A1	gene	biological_process-&-1&-GO:0051013-&&-microtubule severing-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008568-&&-microtubule-severing ATPase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding	G:9606:KATNA1				KATNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KATNA1	0.3895538	0.08669355	32	4	FALSE	KATNA1	KATNA1	148.65625	0	32	0	0.73882674	FALSE	0	KATNA1	68204	0.05373144
790105	taxon:9606	2.56105247	4.42E-05	173865	1902	spectrin repeat containing nuclear envelope protein 2	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0007097-&&-nuclear migration-%%-GO:0010761-&&-fibroblast migration-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0031022-&&-nuclear migration along microfilament-%%-GO:0090286-&&-cytoskeletal anchoring at nuclear membrane-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0021817-&&-nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0051642-&&-centrosome localization|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0031981-&&-nuclear lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031527-&&-filopodium membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016235-&&-aggresome-%%-GO:0034993-&&-LINC complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0003779-&&-actin binding	G:9606:SYNE2				SYNE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNE2	0.39046447	0.06854839	32	4	FALSE	SYNE2	SYNE2	176.3125	0	32	0	0.73982459	FALSE	0	SYNE2	78486	0.06281228
790128	taxon:9606	2.78887663	4.42E-05	173811	1902	caspase recruitment domain family member 8	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0032089-&&-NACHT domain binding-%%-GO:0005515-&&-protein binding	G:9606:CARD8			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	CARD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARD8	0.35856731	0.03448276	32	5	FALSE	CARD8	CARD8	71.86666667	0	31	0	0.70185389	FALSE	1	CARD8	46322	0.0503411
790250	taxon:9606	2.51709469	8.33E-05	173516	1902	extended synaptotagmin 1	gene	biological_process-&-1&-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0044232-&&-organelle membrane contact site|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:ESYT1				ESYT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESYT1	0.39728343	0.10344828	32	4	FALSE	ESYT1	ESYT1	257.4666667	0	31	0	0.74715088	FALSE	1	ESYT1	140018	0.08382752
790299	taxon:9606	2.70332441	1.13E-04	173390	1902	kallikrein related peptidase 5	gene	biological_process-&-1&-GO:0002803-&&-positive regulation of antibacterial peptide production-%%-GO:0008544-&&-epidermis development-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0006508-&&-proteolysis-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0097209-&&-epidermal lamellar body-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008233-&&-peptidase activity	G:9606:KLK5				KLK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK5	0.36991491	0.03830645	32	4	FALSE	KLK5	KLK5	90.59375	0	32	0	0.7161126	FALSE	0	KLK5	110268	0.04728489
790331	taxon:9606	2.6782732	2.90E-05	173302	1902	WW domain containing transcription regulator 1	gene	biological_process-&-1&-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0032835-&&-glomerulus development-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060390-&&-regulation of SMAD protein import into nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0035329-&&-hippo signaling-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0017145-&&-stem cell division-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0060993-&&-kidney morphogenesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0072307-&&-regulation of metanephric nephron tubule epithelial cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003714-&&-transcription corepressor activity	G:9606:WWTR1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	WWTR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WWTR1	0.3733749	0.13709677	32	4	FALSE	WWTR1	WWTR1	140.3125	0	32	0	0.7202878	FALSE	0	WWTR1	47902	0.06710747
790374	taxon:9606	2.70757838	3.24E-05	173184	1902	dimethylarginine dimethylaminohydrolase 2	gene	biological_process-&-1&-GO:0006527-&&-arginine catabolic process-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0000052-&&-citrulline metabolic process-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0016403-&&-dimethylargininase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003824-&&-catalytic activity-%%-GO:0016597-&&-amino acid binding	G:9606:DDAH2				DDAH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDAH2	0.36933372	0.04233871	32	4	FALSE	DDAH2	DDAH2	117.59375	0	32	0	0.7154036	FALSE	0	DDAH2	53018	0.06175948
790469	taxon:9606	2.44068064	1.09E-04	172769	1902	DNA polymerase delta interacting protein 2	gene	biological_process-&-1&-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:0070584-&&-mitochondrion morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:POLDIP2				POLDIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLDIP2	0.40972177	0.13104839	32	4	FALSE	POLDIP2	POLDIP2	212.03125	0	32	0	0.75988656	FALSE	0	POLDIP2	155534	0.05946534
790525	taxon:9606	2.44981881	1.02E-04	172597	1902	ring finger protein 115	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0043162-&&-ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF115				RNF115	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF115	0.40819345	0.11034483	32	4	FALSE	RNF115	RNF115	223.7333333	0	31	0	0.75836353	FALSE	1	RNF115	121386	0.06411433
790614	taxon:9606	2.60564046	4.13E-05	171762	1902	zinc finger and BTB domain containing 7A	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:ZBTB7A				ZBTB7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB7A	0.3837828	0.28275862	32	4	FALSE	ZBTB7A	ZBTB7A	190.8666667	0	31	0	0.73239326	FALSE	1	ZBTB7A	57454	0.07516417
790686	taxon:9606	2.53300772	3.80E-05	171478	1902	SAP30 binding protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SAP30BP				SAP30BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAP30BP	0.39478758	0.14516129	32	4	FALSE	SAP30BP	SAP30BP	198.3125	0	32	0	0.74449871	FALSE	0	SAP30BP	59520	0.06623789
790740	taxon:9606	2.71214747	2.39E-05	171345	1902	ankyrin repeat and SOCS box containing 3	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:ASB3				ASB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB3	0.36871151	0.06451613	32	5	FALSE	ASB3	ASB3	110.125	0	32	0	0.71464209	FALSE	0	ASB3	49366	0.05830125
790810	taxon:9606	2.53568615	8.08E-05	171136	1902	EH domain containing 4	gene	biological_process-&-1&-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032456-&&-endocytic recycling-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0006907-&&-pinocytosis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:EHD4			KEGG-&-1&-hsa04144-&&-Endocytosis	EHD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHD4	0.39437057	0.13508065	32	4	FALSE	EHD4	EHD4	197.375	0	32	0	0.74405231	FALSE	0	EHD4	110130	0.06626721
790893	taxon:9606	2.58815188	4.26E-05	170754	1902	negative elongation factor complex member C/D	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0050434-&&-positive regulation of viral transcription|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0032021-&&-NELF complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NELFCD				NELFCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NELFCD	0.38637609	0.0766129	32	4	FALSE	NELFCD	NELFCD	153.1875	0	32	0	0.73530802	FALSE	0	NELFCD	60654	0.05765066
790971	taxon:9606	2.54324878	5.80E-05	170551	1902	autophagy related 16 like 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0016236-&&-macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0039689-&&-negative stranded viral RNA replication|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005776-&&-autophagosome-%%-GO:0005930-&&-axoneme-%%-GO:0000421-&&-autophagosome membrane-%%-GO:0034045-&&-pre-autophagosomal structure membrane|molecular_function-&-1&-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ATG16L1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04136-&&-Autophagy - other	ATG16L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG16L1	0.39319787	0.15402299	32	4	FALSE	ATG16L1	ATG16L1	178.0333333	0	31	0	0.74279187	FALSE	1	ATG16L1	80408	0.06098926
791017	taxon:9606	2.58311013	4.62E-05	170365	1902	nudE neurodevelopment protein 1	gene	biological_process-&-1&-GO:0021987-&&-cerebral cortex development-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0001764-&&-neuron migration-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0051301-&&-cell division-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051303-&&-establishment of chromosome localization-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0047496-&&-vesicle transport along microtubule-%%-GO:0051298-&&-centrosome duplication-%%-GO:2000574-&&-regulation of microtubule motor activity-%%-GO:0007405-&&-neuroblast proliferation-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0000776-&&-kinetochore-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005874-&&-microtubule-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:NDE1				NDE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDE1	0.38713022	0.10574713	32	4	FALSE	NDE1	NDE1	163.5	0	31	0	0.73614831	FALSE	1	NDE1	66708	0.06109657
791074	taxon:9606	2.56829998	6.08E-05	170136	1902	microtubule associated protein 1S	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0007399-&&-nervous system development-%%-GO:0007420-&&-brain development-%%-GO:0010848-&&-regulation of chromatin disassembly-%%-GO:0006914-&&-autophagy-%%-GO:0047497-&&-mitochondrion transport along microtubule-%%-GO:0048812-&&-neuron projection morphogenesis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0045202-&&-synapse-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0042995-&&-cell projection-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0004536-&&-deoxyribonuclease activity-%%-GO:0015631-&&-tubulin binding	G:9606:MAP1S				MAP1S	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1S	0.38936262	0.08870968	32	4	FALSE	MAP1S	MAP1S	149.75	0	32	0	0.73861667	FALSE	0	MAP1S	86990	0.05425363
791123	taxon:9606	2.59524185	1.93E-05	169959	1902	lysine methyltransferase 2E	gene	biological_process-&-1&-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0006306-&&-DNA methylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0042119-&&-neutrophil activation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:KMT2E			KEGG-&-1&-hsa00310-&&-Lysine degradation	KMT2E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2E	0.38532054	0.125	32	4	FALSE	KMT2E	KMT2E	170.34375	0	32	0	0.73412636	FALSE	0	KMT2E	38808	0.0649938
791132	taxon:9606	2.48952261	2.68E-05	169947	1902	NFKB repressing factor	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:NKRF				NKRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKRF	0.40168344	0.21169355	32	4	FALSE	NKRF	NKRF	319.96875	0	32	0	0.75174623	FALSE	0	NKRF	75430	0.09840385
791176	taxon:9606	2.65432488	9.34E-05	169819	1902	docking protein 4	gene	biological_process-&-1&-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK4				DOK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK4	0.37674363	0.09879032	32	4	FALSE	DOK4	DOK4	117.53125	0	32	0	0.72427919	FALSE	0	DOK4	105222	0.05285755
791193	taxon:9606	2.58720655	7.42E-05	169776	1902	exocyst complex component 1	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0006887-&&-exocytosis-%%-GO:0051601-&&-exocyst localization-%%-GO:0015031-&&-protein transport-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0006893-&&-Golgi to plasma membrane transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000145-&&-exocyst-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0098592-&&-cytoplasmic side of apical plasma membrane|molecular_function-&-1&-GO:0017049-&&-GTP-Rho binding-%%-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding	G:9606:EXOC1				EXOC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC1	0.38651726	0.14112903	32	4	FALSE	EXOC1	EXOC1	149.4375	0	32	0	0.73546557	FALSE	0	EXOC1	87808	0.05612317
791553	taxon:9606	2.63793918	4.87E-05	168052	1902	mitochondrial E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0006915-&&-apoptotic process-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:1901028-&&-regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0071650-&&-negative regulation of chemokine (C-C motif) ligand 5 production-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0010637-&&-negative regulation of mitochondrial fusion-%%-GO:0060339-&&-negative regulation of type I interferon-mediated signaling pathway-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0051646-&&-mitochondrion localization-%%-GO:0050689-&&-negative regulation of defense response to virus by host-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:1904925-&&-positive regulation of mitophagy in response to mitochondrial depolarization-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0016925-&&-protein sumoylation-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0050821-&&-protein stabilization-%%-GO:0031648-&&-protein destabilization|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0030424-&&-axon|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019789-&&-SUMO transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:MUL1				MUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MUL1	0.3790838	0.06896552	32	4	FALSE	MUL1	MUL1	150.5333333	0	31	0	0.72701014	FALSE	1	MUL1	71534	0.06410694
791757	taxon:9606	2.78950685	3.51E-05	166998	1902	keratin associated protein 9-2	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KRTAP9-2				KRTAP9-2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP9-2	0.3584863	0.32183908	32	4	FALSE	KRTAP9-2	KRTAP9-2	82.86666667	0	31	0	0.70174886	FALSE	1	KRTAP9-2	52388	0.05708046
791764	taxon:9606	2.64376871	4.60E-05	166964	1902	ATR interacting protein	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:ATRIP			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	ATRIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATRIP	0.37824791	0.18145161	32	4	FALSE	ATRIP	ATRIP	144.65625	0	32	0	0.72603855	FALSE	0	ATRIP	66748	0.06275782
791907	taxon:9606	2.68819915	3.02E-05	166511	1902	ubiquitin like 7	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UBL7				UBL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBL7	0.37199625	0.10080645	32	4	FALSE	UBL7	UBL7	110.15625	0	32	0	0.71863348	FALSE	0	UBL7	45150	0.05500438
791993	taxon:9606	2.49330392	5.01E-05	182756	1902	adenine phosphoribosyltransferase	gene	biological_process-&-1&-GO:0007625-&&-grooming behavior-%%-GO:0044209-&&-AMP salvage-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006168-&&-adenine salvage-%%-GO:0043101-&&-purine-containing compound salvage-%%-GO:0007595-&&-lactation-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0016208-&&-AMP binding-%%-GO:0002055-&&-adenine binding-%%-GO:0003999-&&-adenine phosphoribosyltransferase activity	G:9606:APRT			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	APRT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APRT	0.40107425	0.15172414	32	4	FALSE	APRT	APRT	250.1	0	31	0	0.75111601	FALSE	1	APRT	80702	0.07782622
792004	taxon:9606	2.47360958	1.09E-04	166360	1902	NIMA related kinase 9	gene	biological_process-&-1&-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:NEK9				NEK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK9	0.40426752	0.12183908	32	4	FALSE	NEK9	NEK9	223.9666667	0	31	0	0.7543984	FALSE	1	NEK9	119340	0.06641953
792148	taxon:9606	2.54529699	1.34E-04	182517	1902	activin A receptor type 1B	gene	biological_process-&-1&-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0046545-&&-development of primary female sexual characteristics-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007417-&&-central nervous system development-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0032927-&&-positive regulation of activin receptor signaling pathway-%%-GO:0001942-&&-hair follicle development-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:1901165-&&-positive regulation of trophoblast cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0048179-&&-activin receptor complex-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0017002-&&-activin-activated receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0048185-&&-activin binding-%%-GO:0034711-&&-inhibin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0016361-&&-activin receptor activity, type I	G:9606:ACVR1B			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	ACVR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVR1B	0.39288146	0.16551724	32	4	FALSE	ACVR1B	ACVR1B	160.9	0	31	0	0.7424505	FALSE	1	ACVR1B	134322	0.05521978
792246	taxon:9606	2.68615094	3.73E-05	182359	1902	ATP synthase, H+ transporting, mitochondrial Fo complex subunit E	gene	biological_process-&-1&-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0000276-&&-mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0015078-&&-hydrogen ion transmembrane transporter activity-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:ATP5I			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa01100-&&-Metabolic pathways	ATP5I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5I	0.3722799	0.18145161	32	4	FALSE	ATP5I	ATP5I	145.25	0	32	0	0.71897484	FALSE	0	ATP5I	69222	0.07050231
792312	taxon:9606	2.63084922	2.39E-05	182247	1902	centromere protein E	gene	biological_process-&-1&-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007079-&&-mitotic chromosome movement towards spindle pole-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051301-&&-cell division-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0099607-&&-lateral attachment of mitotic spindle microtubules to kinetochore-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0051382-&&-kinetochore assembly-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007059-&&-chromosome segregation-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0000940-&&-condensed chromosome outer kinetochore-%%-GO:0005694-&&-chromosome-%%-GO:0000776-&&-kinetochore-%%-GO:0005874-&&-microtubule-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005871-&&-kinesin complex-%%-GO:0005829-&&-cytosol-%%-GO:0000779-&&-condensed chromosome, centromeric region-%%-GO:1990023-&&-mitotic spindle midzone-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0043515-&&-kinetochore binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0005524-&&-ATP binding	G:9606:CENPE				CENPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPE	0.3801054	0.07356322	32	4	FALSE	CENPE	CENPE	140	0	31	0	0.7281918	FALSE	1	CENPE	46024	0.05882105
792434	taxon:9606	2.68772648	2.20E-05	182031	1902	cleavage stimulation factor subunit 1	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSTF1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CSTF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTF1	0.37206167	0.12183908	32	4	FALSE	CSTF1	CSTF1	131	0	31	0	0.71871225	FALSE	1	CSTF1	38480	0.06368208
792451	taxon:9606	2.7677643	1.27E-04	182002	1902	cathepsin G	gene	biological_process-&-1&-GO:0050778-&&-positive regulation of immune response-%%-GO:0002003-&&-angiotensin maturation-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0050832-&&-defense response to fungus-%%-GO:0006508-&&-proteolysis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0016485-&&-protein processing-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0070946-&&-neutrophil mediated killing of gram-positive bacterium-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0030141-&&-secretory granule|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008201-&&-heparin binding	G:9606:CTSG			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa04142-&&-Lysosome-%%-hsa04614-&&-Renin-angiotensin system-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CTSG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSG	0.36130244	0.02419355	32	4	FALSE	CTSG	CTSG	71.75	0	32	0	0.70537262	FALSE	0	CTSG	117952	0.04731076
792716	taxon:9606	2.66519616	5.70E-05	181505	1902	cytochrome b5 reductase 3	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0008015-&&-blood circulation-%%-GO:0019852-&&-L-ascorbic acid metabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005833-&&-hemoglobin complex-%%-GO:0005811-&&-lipid particle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004128-&&-cytochrome-b5 reductase activity, acting on NAD(P)H-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0051287-&&-NAD binding-%%-GO:0016208-&&-AMP binding-%%-GO:0043531-&&-ADP binding	G:9606:CYB5R3			KEGG-&-1&-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	CYB5R3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYB5R3	0.3752069	0.08505747	32	4	FALSE	CYB5R3	CYB5R3	128.0666667	0	31	0	0.72246731	FALSE	1	CYB5R3	85286	0.05823092
792904	taxon:9606	2.62706791	4.38E-05	181189	1902	nuclear receptor subfamily 5 group A member 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0009888-&&-tissue development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000195-&&-negative regulation of female gonad development-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0001553-&&-luteinization-%%-GO:0050810-&&-regulation of steroid biosynthetic process-%%-GO:0008584-&&-male gonad development-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:2000020-&&-positive regulation of male gonad development-%%-GO:0030325-&&-adrenal gland development-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0007538-&&-primary sex determination-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:NR5A1	NR5A1	TRUE	KEGG-&-1&-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	NR5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR5A1	0.38065251	0.16532258	32	5	FALSE	NR5A1	NR5A1	159.03125	0	32	0	0.72882202	FALSE	0	NR5A1	72706	0.06611227
793004	taxon:9606	2.71214747	2.39E-05	148220	1902	GPR75-ASB3 readthrough	gene		G:9606:GPR75-ASB3				GPR75-ASB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPR75-ASB3	0.36871151	0.06451613	32	5	FALSE	GPR75-ASB3	GPR75-ASB3	110.125	0	32	0	0.71464209	FALSE	0	GPR75-ASB3	49366	0.05830125
793145	taxon:9606	2.66251772	5.94E-05	180645	1902	glyoxalase I	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0009438-&&-methylglyoxal metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0030316-&&-osteoclast differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004462-&&-lactoylglutathione lyase activity	G:9606:GLO1			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism	GLO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLO1	0.37558435	0.15632184	32	4	FALSE	GLO1	GLO1	129.7666667	0	31	0	0.72291371	FALSE	1	GLO1	67606	0.0591545
793167	taxon:9606	2.7099417	1.12E-04	180607	1902	G protein subunit alpha z	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0044297-&&-cell body-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0046872-&&-metal ion binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0031821-&&-G-protein coupled serotonin receptor binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding	G:9606:GNAZ			KEGG-&-1&-hsa04730-&&-Long-term depression	GNAZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAZ	0.36901163	0.02758621	32	4	FALSE	GNAZ	GNAZ	87.03333333	0	31	0	0.71500972	FALSE	1	GNAZ	111986	0.04618946
793185	taxon:9606	2.78982196	6.21E-05	180564	1902	homeobox D13	gene	biological_process-&-1&-GO:0048619-&&-embryonic hindgut morphogenesis-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0060687-&&-regulation of branching involved in prostate gland morphogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001501-&&-skeletal system development-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060602-&&-branch elongation of an epithelium-%%-GO:0030539-&&-male genitalia development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0033574-&&-response to testosterone-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0060571-&&-morphogenesis of an epithelial fold|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:HOXD13	HOXD13	TRUE		HOXD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXD13	0.35844581	0.06653226	32	4	FALSE	HOXD13	HOXD13	84.34375	0	32	0	0.70169634	FALSE	0	HOXD13	75528	0.05710401
793249	taxon:9606	2.70253663	3.72E-05	180451	1902	inhibitor of DNA binding 3, HLH protein	gene	biological_process-&-1&-GO:0030903-&&-notochord development-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0007507-&&-heart development-%%-GO:0007517-&&-muscle organ development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009611-&&-response to wounding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007417-&&-central nervous system development-%%-GO:0072750-&&-cellular response to leptomycin B-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0042476-&&-odontogenesis-%%-GO:0007623-&&-circadian rhythm-%%-GO:0001656-&&-metanephros development-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:1901707-&&-leptomycin B binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:ID3			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04350-&&-TGF-beta signaling pathway	ID3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ID3	0.37002274	0.07126437	32	5	FALSE	ID3	ID3	101.8333333	0	31	0	0.71624389	FALSE	1	ID3	54642	0.05188968
787071	taxon:9606	2.61320309	9.18E-05	180117	1902	insulin like growth factor 2 receptor	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001889-&&-liver development-%%-GO:0009791-&&-post-embryonic development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0032526-&&-response to retinoic acid|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0030133-&&-transport vesicle-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0030118-&&-clathrin coat-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0016020-&&-membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0005010-&&-insulin-like growth factor-activated receptor activity-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0005515-&&-protein binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0001972-&&-retinoic acid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005215-&&-transporter activity-%%-GO:0004872-&&-receptor activity	G:9606:IGF2R	IGF2R	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04142-&&-Lysosome	IGF2R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2R	0.38267213	0.09605911	31	4	FALSE	IGF2R	IGF2R	160.8965517	0	30	0	0.73113282	FALSE	1	IGF2R	108056	0.06473152
787085	taxon:9606	2.55128407	1.21E-04	180099	1902	immunoglobulin heavy constant gamma 1 (G1m marker)	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0006956-&&-complement activation-%%-GO:0045087-&&-innate immune response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006508-&&-proteolysis-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0050871-&&-positive regulation of B cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042571-&&-immunoglobulin complex, circulating-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0003823-&&-antigen binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0034987-&&-immunoglobulin receptor binding	G:9606:IGHG1				IGHG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGHG1	0.39195949	0.0862069	31	4	FALSE	IGHG1	IGHG1	211.9655172	0	30	0	0.74145265	FALSE	1	IGHG1	133690	0.07392603
787142	taxon:9606	2.6667717	2.44E-05	179989	1902	LIM domain kinase 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:LIMK2			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	LIMK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIMK2	0.37498523	0.05376344	31	4	FALSE	LIMK2	LIMK2	130.8064516	0	31	0	0.72220472	FALSE	0	LIMK2	45170	0.0604092
787240	taxon:9606	2.66125729	6.35E-05	179814	1902	interleukin 1 receptor associated kinase 2	gene	biological_process-&-1&-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0001959-&&-regulation of cytokine-mediated signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0007254-&&-JNK cascade-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:IRAK2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05152-&&-Tuberculosis	IRAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRAK2	0.37576224	0.11576355	31	4	FALSE	IRAK2	IRAK2	126.7241379	0	30	0	0.72312379	FALSE	1	IRAK2	69860	0.05740871
787365	taxon:9606	2.82810777	2.56E-05	179557	1902	mevalonate diphosphate decarboxylase	gene	biological_process-&-1&-GO:0008299-&&-isoprenoid biosynthetic process-%%-GO:0019287-&&-isopentenyl diphosphate biosynthetic process, mevalonate pathway-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0006489-&&-dolichyl diphosphate biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005777-&&-peroxisome|molecular_function-&-1&-GO:0004163-&&-diphosphomevalonate decarboxylase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MVD			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis-%%-hsa01100-&&-Metabolic pathways	MVD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MVD	0.35359331	0.18226601	31	5	FALSE	MVD	MVD	64.79310345	0	30	0	0.69531537	FALSE	1	MVD	30398	0.05422855
787385	taxon:9606	2.55128407	2.60E-05	179517	1902	myosin ID	gene	biological_process-&-1&-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0061502-&&-early endosome to recycling endosome transport-%%-GO:0051641-&&-cellular localization-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0016459-&&-myosin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0097440-&&-apical dendrite-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043209-&&-myelin sheath-%%-GO:0044853-&&-plasma membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0030673-&&-axolemma-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005903-&&-brush border|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030898-&&-actin-dependent ATPase activity	G:9606:MYO1D				MYO1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO1D	0.39195949	0.09892473	31	4	FALSE	MYO1D	MYO1D	202.1290323	0	31	0	0.74145265	FALSE	0	MYO1D	63256	0.07025164
787486	taxon:9606	2.69465889	5.35E-05	179350	1902	mitogen-activated protein kinase kinase kinase 10	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0007256-&&-activation of JNKK activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007254-&&-JNK cascade-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004706-&&-JUN kinase kinase kinase activity-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAP3K10				MAP3K10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K10	0.37110448	0.0591133	31	4	FALSE	MAP3K10	MAP3K10	113.3448276	0	30	0	0.71755685	FALSE	1	MAP3K10	59384	0.05736629
787494	taxon:9606	2.60485269	3.90E-05	179340	1902	nuclear receptor subfamily 3 group C member 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005496-&&-steroid binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:NR3C2	NR3C2	TRUE	KEGG-&-1&-hsa04960-&&-Aldosterone-regulated sodium reabsorption	NR3C2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR3C2	0.38389887	0.2	31	4	FALSE	NR3C2	NR3C2	171.8709677	0	31	0	0.73252455	FALSE	0	NR3C2	55422	0.06738886
787610	taxon:9606	2.54608476	3.76E-05	179104	1902	nuclear transcription factor Y subunit beta	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016602-&&-CCAAT-binding factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0070491-&&-repressing transcription factor binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:NFYB			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis	NFYB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFYB	0.3927599	0.23225806	31	4	FALSE	NFYB	NFYB	196.7096774	0	31	0	0.74231921	FALSE	0	NFYB	60534	0.06749499
787787	taxon:9606	2.57806838	9.53E-06	162405	1902	histone cluster 1 H2A family member a	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AA			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AA	0.38788731	0.41505376	31	4	FALSE	HIST1H2AA	HIST1H2AA	307.2258065	0	31	0	0.7369886	FALSE	0	HIST1H2AA	32932	0.11252511
787822	taxon:9606	2.69276824	7.59E-05	178744	1902	protein kinase, cGMP-dependent, type I	gene	biological_process-&-1&-GO:0001764-&&-neuron migration-%%-GO:0060087-&&-relaxation of vascular smooth muscle-%%-GO:0016358-&&-dendrite development-%%-GO:0030900-&&-forebrain development-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0007165-&&-signal transduction-%%-GO:0019934-&&-cGMP-mediated signaling-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004692-&&-cGMP-dependent protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0030553-&&-cGMP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PRKG1			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04714-&&-Thermogenesis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04611-&&-Platelet activation-%%-hsa04740-&&-Olfactory transduction-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	PRKG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKG1	0.37136505	0.04679803	31	5	FALSE	PRKG1	PRKG1	102.3793103	0	30	0	0.71787196	FALSE	1	PRKG1	76694	0.05130785
787828	taxon:9606	2.7245943	4.81E-05	162356	1902	ligand of numb-protein X 2	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:LNX2				LNX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LNX2	0.36702712	0.0591133	31	4	FALSE	LNX2	LNX2	89.31034483	0	30	0	0.71256762	FALSE	1	LNX2	49782	0.04982344
787843	taxon:9606	2.54435166	5.35E-05	178730	1902	mitogen-activated protein kinase kinase 3	gene	biological_process-&-1&-GO:0035897-&&-proteolysis in other organism-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042035-&&-regulation of cytokine biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity	G:9606:MAP2K3			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	MAP2K3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K3	0.39302743	0.11083744	31	4	FALSE	MAP2K3	MAP2K3	165.5862069	0	30	0	0.74260806	FALSE	1	MAP2K3	81618	0.05673046
787953	taxon:9606	2.67575232	9.57E-05	162132	1902	KAT8 regulatory NSL complex subunit 1	gene	biological_process-&-1&-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0005515-&&-protein binding	G:9606:KANSL1				KANSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KANSL1	0.37372667	0.05591398	31	4	FALSE	KANSL1	KANSL1	112.6451613	0	31	0	0.72070795	FALSE	0	KANSL1	108500	0.05307807
788118	taxon:9606	2.56593666	5.27E-05	178208	1902	protein tyrosine phosphatase, receptor type B	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRB			KEGG-&-1&-hsa04520-&&-Adherens junction	PTPRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRB	0.38972123	0.18226601	31	4	FALSE	PTPRB	PTPRB	175.7241379	0	30	0	0.73901056	FALSE	1	PTPRB	77678	0.06332198
788120	taxon:9606	2.55506539	1.49E-05	178210	1902	protein tyrosine phosphatase, non-receptor type 14	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding	G:9606:PTPN14				PTPN14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN14	0.39137942	0.21290323	31	4	FALSE	PTPN14	PTPN14	204.3870968	0	31	0	0.74082244	FALSE	0	PTPN14	36894	0.07153906
788131	taxon:9606	2.48132976	2.87E-05	178195	1902	protein tyrosine phosphatase, receptor type O	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0072112-&&-glomerular visceral epithelial cell differentiation-%%-GO:0003093-&&-regulation of glomerular filtration-%%-GO:0032835-&&-glomerulus development-%%-GO:0090260-&&-negative regulation of retinal ganglion cell axon guidance-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0036060-&&-slit diaphragm assembly-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0003105-&&-negative regulation of glomerular filtration-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043197-&&-dendritic spine-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0016791-&&-phosphatase activity	G:9606:PTPRO				PTPRO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRO	0.40300971	0.20197044	31	4	FALSE	PTPRO	PTPRO	213	0	30	0	0.75311171	FALSE	1	PTPRO	69212	0.06460419
788249	taxon:9606	2.67449189	2.10E-05	178006	1902	regulatory factor X5	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RFX5			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05152-&&-Tuberculosis-%%-hsa05340-&&-Primary immunodeficiency	RFX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFX5	0.3739028	0.16774194	31	4	FALSE	RFX5	RFX5	235.1290323	0	31	0	0.72091802	FALSE	0	RFX5	64122	0.10991301
788259	taxon:9606	2.78257444	6.35E-05	177990	1902	Ras homolog enriched in brain	gene	biological_process-&-1&-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0016236-&&-macroautophagy-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:2000074-&&-regulation of type B pancreatic cell development|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:RHEB			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04218-&&-Cellular senescence-%%-hsa04150-&&-mTOR signaling pathway	RHEB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHEB	0.35937942	0.0688172	31	4	FALSE	RHEB	RHEB	72.64516129	0	31	0	0.70290426	FALSE	0	RHEB	64294	0.05148002
788302	taxon:9606	2.51441626	2.94E-05	177930	1902	ribonucleotide reductase regulatory subunit M2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0009263-&&-deoxyribonucleotide biosynthetic process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0051290-&&-protein heterotetramerization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004748-&&-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor-%%-GO:0005515-&&-protein binding	G:9606:RRM2			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	RRM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRM2	0.39770662	0.12258065	31	4	FALSE	RRM2	RRM2	176.1935484	0	31	0	0.74759729	FALSE	0	RRM2	56918	0.05695238
788364	taxon:9606	2.57428706	6.87E-05	177797	1902	SEL1L ERAD E3 ligase adaptor subunit	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0036503-&&-ERAD pathway-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0009306-&&-protein secretion-%%-GO:0050821-&&-protein stabilization-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000839-&&-Hrd1p ubiquitin ligase ERAD-L complex-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0000836-&&-Hrd1p ubiquitin ligase complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEL1L			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SEL1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEL1L	0.38845707	0.19569892	31	4	FALSE	SEL1L	SEL1L	160.483871	0	31	0	0.73761882	FALSE	0	SEL1L	92486	0.0593367
788518	taxon:9606	2.59177564	6.56E-05	177513	1902	Sp3 transcription factor	gene	biological_process-&-1&-GO:0048706-&&-embryonic skeletal system development-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030219-&&-megakaryocyte differentiation-%%-GO:0001503-&&-ossification-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030217-&&-T cell differentiation-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0060136-&&-embryonic process involved in female pregnancy-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0001889-&&-liver development-%%-GO:0016925-&&-protein sumoylation-%%-GO:0030324-&&-lung development-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:SP3				SP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP3	0.38583587	0.26236559	31	4	FALSE	SP3	SP3	199.1290323	0	31	0	0.73470406	FALSE	0	SP3	73864	0.07516726
788576	taxon:9606	2.6650386	3.26E-05	177411	1902	TATA-box binding protein associated factor 11	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042809-&&-vitamin D receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:TAF11			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF11	0.37522909	0.24086022	31	4	FALSE	TAF11	TAF11	118.9032258	0	31	0	0.72249357	FALSE	0	TAF11	54494	0.05490576
788603	taxon:9606	2.65684575	2.38E-05	177363	1902	transcription factor 7 like 2	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0048660-&&-regulation of smooth muscle cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001568-&&-blood vessel development-%%-GO:0031016-&&-pancreas development-%%-GO:0044334-&&-canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0009749-&&-response to glucose-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048625-&&-myoblast fate commitment-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0032350-&&-regulation of hormone metabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0010909-&&-positive regulation of heparan sulfate proteoglycan biosynthetic process|cellular_component-&-1&-GO:0070369-&&-beta-catenin-TCF7L2 complex-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0045295-&&-gamma-catenin binding	G:9606:TCF7L2	TCF7L2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05216-&&-Thyroid cancer-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	TCF7L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF7L2	0.37638617	0.13548387	31	4	FALSE	TCF7L2	TCF7L2	144.3225807	0	31	0	0.72385904	FALSE	0	TCF7L2	43026	0.06514264
788636	taxon:9606	2.63589097	3.57E-05	177278	1902	transcription factor Dp-1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0070345-&&-negative regulation of fat cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:TFDP1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04350-&&-TGF-beta signaling pathway	TFDP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFDP1	0.37937836	0.18924731	31	4	FALSE	TFDP1	TFDP1	147	0	31	0	0.7273515	FALSE	0	TFDP1	55198	0.06177711
788682	taxon:9606	2.64818024	6.82E-05	177201	1902	toll like receptor 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070542-&&-response to fatty acid-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0002374-&&-cytokine secretion involved in immune response-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0071726-&&-cellular response to diacyl bacterial lipopeptide-%%-GO:0032868-&&-response to insulin-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006955-&&-immune response-%%-GO:0032570-&&-response to progesterone-%%-GO:0006915-&&-apoptotic process-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0032289-&&-central nervous system myelin formation-%%-GO:0042496-&&-detection of diacyl bacterial lipopeptide-%%-GO:0038123-&&-toll-like receptor TLR1:TLR2 signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032741-&&-positive regulation of interleukin-18 production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0038124-&&-toll-like receptor TLR6:TLR2 signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0048714-&&-positive regulation of oligodendrocyte differentiation-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0001666-&&-response to hypoxia-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0001774-&&-microglial cell activation-%%-GO:0042495-&&-detection of triacyl bacterial lipopeptide-%%-GO:0071221-&&-cellular response to bacterial lipopeptide-%%-GO:0032613-&&-interleukin-10 production-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071727-&&-cellular response to triacyl bacterial lipopeptide-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0034123-&&-positive regulation of toll-like receptor signaling pathway-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0046209-&&-nitric oxide metabolic process-%%-GO:0050707-&&-regulation of cytokine secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0035354-&&-Toll-like receptor 1-Toll-like receptor 2 protein complex-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0044297-&&-cell body-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0042995-&&-cell projection-%%-GO:0009986-&&-cell surface-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030670-&&-phagocytic vesicle membrane|molecular_function-&-1&-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005515-&&-protein binding-%%-GO:0001875-&&-lipopolysaccharide receptor activity-%%-GO:0042834-&&-peptidoglycan binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0042497-&&-triacyl lipopeptide binding-%%-GO:0004872-&&-receptor activity-%%-GO:0008329-&&-signaling pattern recognition receptor activity-%%-GO:0035325-&&-Toll-like receptor binding	G:9606:TLR2	TLR2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	TLR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLR2	0.3776178	0.06896552	31	4	FALSE	TLR2	TLR2	119.0344828	0	30	0	0.72530329	FALSE	1	TLR2	76294	0.05282041
788687	taxon:9606	2.62486214	4.64E-05	177184	1902	thymosin beta 4, X-linked	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0007015-&&-actin filament organization-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0005515-&&-protein binding	G:9606:TMSB4X			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	TMSB4X	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMSB4X	0.38097239	0.12688172	31	4	FALSE	TMSB4X	TMSB4X	149.2903226	0	31	0	0.72918964	FALSE	0	TMSB4X	71730	0.06175001
788739	taxon:9606	2.69276824	8.47E-05	177062	1902	thyroid stimulating hormone receptor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007399-&&-nervous system development-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0038194-&&-thyroid-stimulating hormone signaling pathway-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0008528-&&-G-protein coupled peptide receptor activity-%%-GO:0004996-&&-thyroid-stimulating hormone receptor activity-%%-GO:0005515-&&-protein binding	G:9606:TSHR			KEGG-&-1&-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	TSHR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSHR	0.37136505	0.06650246	31	4	FALSE	TSHR	TSHR	104.6896552	0	30	0	0.71787196	FALSE	1	TSHR	80996	0.05282354
788743	taxon:9606	2.66803214	4.66E-05	177048	1902	tetratricopeptide repeat domain 4	gene		G:9606:TTC4				TTC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC4	0.37480808	0.11182796	31	4	FALSE	TTC4	TTC4	115.9032258	0	31	0	0.72199464	FALSE	0	TTC4	55994	0.05346558
788776	taxon:9606	2.48731684	2.92E-05	176922	1902	mannosyl-oligosaccharide glucosidase	gene	biological_process-&-1&-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0006457-&&-protein folding-%%-GO:0009311-&&-oligosaccharide metabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004573-&&-mannosyl-oligosaccharide glucosidase activity-%%-GO:0015926-&&-glucosidase activity	G:9606:MOGS			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	MOGS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOGS	0.40203965	0.13333333	31	4	FALSE	MOGS	MOGS	229.3548387	0	31	0	0.75211386	FALSE	0	MOGS	73534	0.07017215
788938	taxon:9606	2.69922798	2.34E-05	176557	1902	SPT3 homolog, SAGA and STAGA complex component	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0016578-&&-histone deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030914-&&-STAGA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:SUPT3H			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	SUPT3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT3H	0.3704763	0.35268817	31	4	FALSE	SUPT3H	SUPT3H	120.0645161	0	31	0	0.71679534	FALSE	0	SUPT3H	39208	0.05908687
788959	taxon:9606	2.63463053	4.77E-05	176528	1902	plakophilin 4	gene	biological_process-&-1&-GO:0007043-&&-cell-cell junction assembly-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0031424-&&-keratinization-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0070268-&&-cornification-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0030496-&&-midbody-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0072686-&&-mitotic spindle-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030057-&&-desmosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0001533-&&-cornified envelope-%%-GO:0051233-&&-spindle midzone|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PKP4				PKP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKP4	0.37955986	0.06021505	31	4	FALSE	PKP4	PKP4	121.9677419	0	31	0	0.72756158	FALSE	0	PKP4	66998	0.0517722
788997	taxon:9606	2.7015913	2.06E-05	176434	1902	lysine methyltransferase 2D	gene	biological_process-&-1&-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0048477-&&-oogenesis-%%-GO:0001555-&&-oocyte growth-%%-GO:0006342-&&-chromatin silencing-%%-GO:0043627-&&-response to estrogen-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0035097-&&-histone methyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0044666-&&-MLL3/4 complex|molecular_function-&-1&-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)-%%-GO:0003677-&&-DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:KMT2D			KEGG-&-1&-hsa04934-&&-Cushing syndrome-%%-hsa00310-&&-Lysine degradation	KMT2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT2D	0.37015221	0.18924731	31	5	FALSE	KMT2D	KMT2D	122.0967742	0	31	0	0.71640145	FALSE	0	KMT2D	36438	0.06197548
789151	taxon:9606	2.74885773	1.17E-05	176098	1902	protein regulator of cytokinesis 1	gene	biological_process-&-1&-GO:0000022-&&-mitotic spindle elongation-%%-GO:0000910-&&-cytokinesis-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000922-&&-spindle pole-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0070938-&&-contractile ring-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding	G:9606:PRC1				PRC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRC1	0.36378747	0.18064516	31	4	FALSE	PRC1	PRC1	222.0645161	0	31	0	0.70852371	FALSE	0	PRC1	41320	0.12955954
789343	taxon:9606	2.49550969	7.53E-05	175696	1902	CCR4-NOT transcription complex subunit 9	gene	biological_process-&-1&-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0007548-&&-sex differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2000327-&&-positive regulation of ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway|cellular_component-&-1&-GO:0030014-&&-CCR4-NOT complex-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0016020-&&-membrane-%%-GO:0030015-&&-CCR4-NOT core complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:CNOT9			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT9	0.40071974	0.17980296	31	4	FALSE	CNOT9	CNOT9	219.2758621	0	30	0	0.75074839	FALSE	1	CNOT9	99086	0.06824646
789370	taxon:9606	2.47345202	7.79E-05	175650	1902	zw10 kinetochore protein	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0015031-&&-protein transport-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0051301-&&-cell division-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0007126-&&-meiotic nuclear division-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007030-&&-Golgi organization-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0034501-&&-protein localization to kinetochore|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005828-&&-kinetochore microtubule-%%-GO:0070939-&&-Dsl1/NZR complex-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:1990423-&&-RZZ complex-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019237-&&-centromeric DNA binding	G:9606:ZW10				ZW10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZW10	0.40429327	0.12043011	31	4	FALSE	ZW10	ZW10	205.0645161	0	31	0	0.75442466	FALSE	0	ZW10	106456	0.06130383
789414	taxon:9606	2.66283283	9.55E-05	175534	1902	transcription elongation factor A like 1	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:TCEAL1				TCEAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEAL1	0.37553991	0.07741935	31	4	FALSE	TCEAL1	TCEAL1	109.7741936	0	31	0	0.72286119	FALSE	0	TCEAL1	93858	0.04996837
789425	taxon:9606	2.55506539	8.99E-05	126363	1902	eukaryotic translation initiation factor 1A, X-chromosomal	gene		G:9606:LOC107984923				LOC107984923	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC107984923	0.39137942	0.07096774	31	4	FALSE	LOC107984923	LOC107984923	160.8709677	0	31	0	0.74082244	FALSE	0	LOC107984923	113924	0.05681987
789578	taxon:9606	2.65448243	2.57E-05	175142	1902	TOX high mobility group box family member 4	gene	cellular_component-&-1&-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TOX4				TOX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOX4	0.37672127	0.13793103	31	4	FALSE	TOX4	TOX4	149.137931	0	30	0	0.72425293	FALSE	1	TOX4	43312	0.06574084
789595	taxon:9606	2.5306444	4.15E-05	175102	1902	ring finger protein 10	gene	biological_process-&-1&-GO:0010626-&&-negative regulation of Schwann cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF10				RNF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF10	0.39515627	0.09247312	31	4	FALSE	RNF10	RNF10	189.9032258	0	31	0	0.7448926	FALSE	0	RNF10	81456	0.06331022
789630	taxon:9606	2.75437214	5.22E-05	175025	1902	steroid receptor RNA activator 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:SRA1	SRA1	TRUE		SRA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRA1	0.36305915	0.09892473	31	4	FALSE	SRA1	SRA1	90.25806452	0	31	0	0.70760464	FALSE	0	SRA1	55932	0.05369283
789632	taxon:9606	2.64109028	3.61E-05	175027	1902	zinc finger and BTB domain containing 33	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008327-&&-methyl-CpG binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB33				ZBTB33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB33	0.37863151	0.1453202	31	4	FALSE	ZBTB33	ZBTB33	155.1724138	0	30	0	0.72648495	FALSE	1	ZBTB33	52978	0.06699848
789744	taxon:9606	2.64471404	3.52E-05	174777	1902	actin related protein 2/3 complex subunit 5	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0097581-&&-lamellipodium organization-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0016477-&&-cell migration-%%-GO:0030011-&&-maintenance of cell polarity-%%-GO:0051639-&&-actin filament network formation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0021769-&&-orbitofrontal cortex development-%%-GO:0031023-&&-microtubule organizing center organization|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0005768-&&-endosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding	G:9606:ARPC5			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05132-&&-Salmonella infection-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05131-&&-Shigellosis	ARPC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARPC5	0.37811271	0.20215054	31	4	FALSE	ARPC5	ARPC5	127.3870968	0	31	0	0.72588099	FALSE	0	ARPC5	52782	0.05574544
789914	taxon:9606	2.54277611	1.29E-05	174378	1902	insulin like growth factor 2 mRNA binding protein 2	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0010467-&&-gene expression-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0042035-&&-regulation of cytokine biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0045182-&&-translation regulator activity-%%-GO:0048027-&&-mRNA 5'-UTR binding	G:9606:IGF2BP2	IGF2BP2	TRUE		IGF2BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2BP2	0.39327096	0.20215054	31	4	FALSE	IGF2BP2	IGF2BP2	272.1935484	0	31	0	0.74287065	FALSE	0	IGF2BP2	42548	0.09304659
790002	taxon:9606	2.51031984	8.37E-05	174143	1902	SEC31 homolog A, COPII coat complex component	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0051592-&&-response to calcium ion-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030120-&&-vesicle coat-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0030127-&&-COPII vesicle coat-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding	G:9606:SEC31A			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC31A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC31A	0.39835561	0.12688172	31	4	FALSE	SEC31A	SEC31A	213.5483871	0	31	0	0.74828003	FALSE	0	SEC31A	111878	0.06809921
790010	taxon:9606	2.54923586	4.66E-05	174123	1902	DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease	gene	biological_process-&-1&-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0071034-&&-CUT catabolic process-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0016075-&&-rRNA catabolic process|cellular_component-&-1&-GO:0000176-&&-nuclear exosome (RNase complex)-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:DIS3			KEGG-&-1&-hsa03018-&&-RNA degradation	DIS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIS3	0.39227441	0.12043011	31	4	FALSE	DIS3	DIS3	188.0967742	0	31	0	0.74179402	FALSE	0	DIS3	80616	0.06466039
790067	taxon:9606	2.56199779	2.33E-05	173957	1902	WD repeat and HMG-box DNA binding protein 1	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:WDHD1				WDHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDHD1	0.3903204	0.12688172	31	4	FALSE	WDHD1	WDHD1	190.483871	0	31	0	0.73966703	FALSE	0	WDHD1	53040	0.0674165
790219	taxon:9606	2.67811565	3.86E-05	173607	1902	golgi associated, gamma adaptin ear containing, ARF binding protein 3	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0061024-&&-membrane organization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0030306-&&-ADP-ribosylation factor binding-%%-GO:0005515-&&-protein binding	G:9606:GGA3			KEGG-&-1&-hsa04142-&&-Lysosome	GGA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GGA3	0.37339687	0.17241379	31	4	FALSE	GGA3	GGA3	119.5517241	0	30	0	0.72031406	FALSE	1	GGA3	49398	0.05694009
790221	taxon:9606	2.52103356	2.36E-05	173602	1902	RTF1 homolog, Paf1/RNA polymerase II complex component	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001711-&&-endodermal cell fate commitment-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0080182-&&-histone H3-K4 trimethylation-%%-GO:0001832-&&-blastocyst growth|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016593-&&-Cdc73/Paf1 complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:1990269-&&-RNA polymerase II C-terminal domain phosphoserine binding-%%-GO:0003723-&&-RNA binding	G:9606:RTF1				RTF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RTF1	0.39666271	0.17204301	31	4	FALSE	RTF1	RTF1	178.5483871	0	31	0	0.74649441	FALSE	0	RTF1	54526	0.05843408
790239	taxon:9606	2.66945013	6.95E-05	173547	1902	ubiquitin protein ligase E3 component n-recognin 2	gene	biological_process-&-1&-GO:0007141-&&-male meiosis I-%%-GO:0071233-&&-cellular response to leucine-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006342-&&-chromatin silencing-%%-GO:0071596-&&-ubiquitin-dependent protein catabolic process via the N-end rule pathway-%%-GO:0033522-&&-histone H2A ubiquitination|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0070728-&&-leucine binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:UBR2				UBR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBR2	0.37460898	0.06236559	31	4	FALSE	UBR2	UBR2	133.3870968	0	31	0	0.72175831	FALSE	0	UBR2	80220	0.06224975
790390	taxon:9606	2.56451867	3.02E-05	173138	1902	Cbl proto-oncogene C	gene	biological_process-&-1&-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:CBLC			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis	CBLC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBLC	0.38993672	0.19139785	31	4	FALSE	CBLC	CBLC	186.483871	0	31	0	0.73924689	FALSE	0	CBLC	61408	0.0672266
790482	taxon:9606	2.70111864	2.47E-05	172728	1902	testin LIM domain protein	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:TES				TES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TES	0.37021699	0.13054187	31	4	FALSE	TES	TES	122.6551724	0	30	0	0.71648023	FALSE	1	TES	38908	0.06260462
790592	taxon:9606	2.6500709	4.90E-05	172024	1902	transmembrane p24 trafficking protein 9	gene	biological_process-&-1&-GO:0032527-&&-protein exit from endoplasmic reticulum-%%-GO:0048205-&&-COPI coating of Golgi vesicle-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007030-&&-Golgi organization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0010638-&&-positive regulation of organelle organization|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding	G:9606:TMED9				TMED9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMED9	0.37734839	0.10107527	31	4	FALSE	TMED9	TMED9	131.1935484	0	31	0	0.72498818	FALSE	0	TMED9	60842	0.05758851
790613	taxon:9606	2.55664093	2.64E-05	171763	1902	crooked neck pre-mRNA splicing factor 1	gene	biological_process-&-1&-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CRNKL1			KEGG-&-1&-hsa03040-&&-Spliceosome	CRNKL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRNKL1	0.39113823	0.29677419	31	4	FALSE	CRNKL1	CRNKL1	259.2580645	0	31	0	0.74055984	FALSE	0	CRNKL1	64492	0.09082686
790620	taxon:9606	2.70017331	4.37E-05	171736	1902	ATPase H+ transporting V1 subunit D	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0061512-&&-protein localization to cilium-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification-%%-GO:0015992-&&-proton transport-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0033176-&&-proton-transporting V-type ATPase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0005515-&&-protein binding	G:9606:ATP6V1D			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05165-&&-Human papillomavirus infection	ATP6V1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V1D	0.3703466	0.10537634	31	4	FALSE	ATP6V1D	ATP6V1D	100.6774194	0	31	0	0.71663778	FALSE	0	ATP6V1D	53690	0.05130992
790646	taxon:9606	2.79234284	2.85E-05	171677	1902	N-terminal EF-hand calcium binding protein 2	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NECAB2				NECAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NECAB2	0.35812221	0.03940887	31	5	FALSE	NECAB2	NECAB2	78.96551724	0	30	0	0.70127619	FALSE	1	NECAB2	36084	0.05355633
790682	taxon:9606	2.74696707	3.65E-05	171483	1902	PYD and CARD domain containing	gene	biological_process-&-1&-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0002277-&&-myeloid dendritic cell activation involved in immune response-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090197-&&-positive regulation of chemokine secretion-%%-GO:2001242-&&-regulation of intrinsic apoptotic signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:2001181-&&-positive regulation of interleukin-10 secretion-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0006954-&&-inflammatory response-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0051607-&&-defense response to virus-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0006915-&&-apoptotic process-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0002588-&&-positive regulation of antigen processing and presentation of peptide antigen via MHC class II-%%-GO:0002821-&&-positive regulation of adaptive immune response-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0001773-&&-myeloid dendritic cell activation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:2001056-&&-positive regulation of cysteine-type endopeptidase activity-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:2000484-&&-positive regulation of interleukin-8 secretion-%%-GO:0045087-&&-innate immune response-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0044351-&&-macropinocytosis-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0005730-&&-nucleolus-%%-GO:0008385-&&-IkappaB kinase complex-%%-GO:0097169-&&-AIM2 inflammasome complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0072558-&&-NLRP1 inflammasome complex-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005739-&&-mitochondrion-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005138-&&-interleukin-6 receptor binding-%%-GO:0032090-&&-Pyrin domain binding-%%-GO:0005523-&&-tropomyosin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0070700-&&-BMP receptor binding-%%-GO:0017024-&&-myosin I binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0002020-&&-protease binding	G:9606:PYCARD			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis	PYCARD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYCARD	0.36403785	0.05665025	31	4	FALSE	PYCARD	PYCARD	91.24137931	0	30	0	0.70883882	FALSE	1	PYCARD	44182	0.05429902
790769	taxon:9606	2.72522452	4.60E-05	171277	1902	zinc finger protein 219	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001505-&&-regulation of neurotransmitter levels-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004969-&&-histamine receptor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZNF219				ZNF219	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF219	0.36694224	0.19784946	31	4	FALSE	ZNF219	ZNF219	112.9354839	0	31	0	0.71246258	FALSE	0	ZNF219	56576	0.06139212
790842	taxon:9606	2.74728218	4.56E-05	170973	1902	peptidylprolyl isomerase like 3	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PPIL3				PPIL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIL3	0.3639961	0.08817204	31	5	FALSE	PPIL3	PPIL3	89.90322581	0	31	0	0.7087863	FALSE	0	PPIL3	55492	0.05371837
790874	taxon:9606	2.58547345	2.27E-05	170807	1902	pseudouridylate synthase 7 (putative)	gene	biological_process-&-1&-GO:0008033-&&-tRNA processing-%%-GO:0001522-&&-pseudouridine synthesis|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0009982-&&-pseudouridine synthase activity-%%-GO:0019899-&&-enzyme binding	G:9606:PUS7				PUS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUS7	0.38677636	0.11182796	31	4	FALSE	PUS7	PUS7	159.483871	0	31	0	0.73575442	FALSE	0	PUS7	41558	0.05979898
790958	taxon:9606	2.59098787	5.37E-05	170601	1902	mitogen-activated protein kinase kinase kinase 20	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030154-&&-cell differentiation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0000075-&&-cell cycle checkpoint-%%-GO:0006950-&&-response to stress-%%-GO:0008283-&&-cell proliferation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0008219-&&-cell death-%%-GO:0009314-&&-response to radiation-%%-GO:0060173-&&-limb development-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAP3K20			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP3K20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K20	0.38595318	0.08866995	31	4	FALSE	MAP3K20	MAP3K20	165.3448276	0	30	0	0.73483536	FALSE	1	MAP3K20	72692	0.06251795
791094	taxon:9606	2.80636521	1.96E-05	170074	1902	PHD finger protein 10	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071564-&&-npBAF complex|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:PHF10			KEGG-&-1&-hsa05225-&&-Hepatocellular carcinoma	PHF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF10	0.35633281	0.34623656	31	4	FALSE	PHF10	PHF10	189.4193548	0	31	0	0.69893913	FALSE	0	PHF10	40986	0.14023895
791105	taxon:9606	2.77170317	3.71E-05	153640	1902	heat shock protein 90 alpha family class A member 5, pseudogene	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:HSP90AA5P				HSP90AA5P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90AA5P	0.36078899	0.10752688	31	4	FALSE	HSP90AA5P	HSP90AA5P	96.03225806	0	31	0	0.70471614	FALSE	0	HSP90AA5P	42946	0.06068026
791157	taxon:9606	2.64849535	4.08E-05	169861	1902	hypoxia inducible factor 1 alpha subunit inhibitor	gene	biological_process-&-1&-GO:0042265-&&-peptidyl-asparagine hydroxylation-%%-GO:0036138-&&-peptidyl-histidine hydroxylation-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0042264-&&-peptidyl-aspartic acid hydroxylation-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0045663-&&-positive regulation of myoblast differentiation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0071532-&&-ankyrin repeat binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0005112-&&-Notch binding-%%-GO:0019826-&&-oxygen sensor activity-%%-GO:0036140-&&-peptidyl-asparagine 3-dioxygenase activity-%%-GO:0031406-&&-carboxylic acid binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0036139-&&-peptidyl-histidine dioxygenase activity-%%-GO:0048037-&&-cofactor binding	G:9606:HIF1AN				HIF1AN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIF1AN	0.37757287	0.10591133	31	4	FALSE	HIF1AN	HIF1AN	138.6896552	0	30	0	0.72525077	FALSE	1	HIF1AN	57564	0.06055987
791249	taxon:9606	2.59981093	2.06E-05	169537	1902	eukaryotic translation initiation factor 4E nuclear import factor 1	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0015031-&&-protein transport-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0045665-&&-negative regulation of neuron differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0016605-&&-PML body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:EIF4ENIF1				EIF4ENIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4ENIF1	0.38464335	0.11827957	31	4	FALSE	EIF4ENIF1	EIF4ENIF1	156.8064516	0	31	0	0.73336484	FALSE	0	EIF4ENIF1	45428	0.06068213
791278	taxon:9606	2.63463053	6.85E-05	169396	1902	NUFIP2, FMR1 interacting protein 2	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016020-&&-membrane-%%-GO:0042788-&&-polysomal ribosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NUFIP2				NUFIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUFIP2	0.37955986	0.11612903	31	4	FALSE	NUFIP2	NUFIP2	153.7096774	0	31	0	0.72756158	FALSE	0	NUFIP2	102424	0.06491185
791438	taxon:9606	2.56436112	7.10E-05	168646	1902	chromosome 8 open reading frame 33	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C8orf33				C8orf33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C8orf33	0.38996068	0.03870968	31	4	FALSE	C8orf33	C8orf33	158.3225807	0	31	0	0.73927315	FALSE	0	C8orf33	96544	0.05694655
791483	taxon:9606	2.49960611	6.38E-05	168449	1902	RNA binding motif protein 26	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0010923-&&-negative regulation of phosphatase activity|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RBM26				RBM26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM26	0.40006303	0.08817204	31	4	FALSE	RBM26	RBM26	210.8064516	0	31	0	0.75006565	FALSE	0	RBM26	102386	0.06576496
791670	taxon:9606	2.69481645	4.89E-05	167497	1902	WD repeat and coiled coil containing	gene	biological_process-&-1&-GO:0051259-&&-protein oligomerization|molecular_function-&-1&-GO:0019900-&&-kinase binding	G:9606:WDCP				WDCP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDCP	0.37108279	0.03655914	31	4	FALSE	WDCP	WDCP	102.3870968	0	31	0	0.71753059	FALSE	0	WDCP	61468	0.05125917
791801	taxon:9606	2.62249882	6.16E-05	166797	1902	caspase recruitment domain family member 11	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0045061-&&-thymic T cell selection-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0031295-&&-T cell costimulation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0045580-&&-regulation of T cell differentiation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0070970-&&-interleukin-2 secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0001772-&&-immunological synapse-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0050700-&&-CARD domain binding	G:9606:CARD11			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	CARD11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARD11	0.38131571	0.21674877	31	4	FALSE	CARD11	CARD11	150.0344828	0	30	0	0.72958353	FALSE	1	CARD11	82314	0.06212325
791830	taxon:9606	2.53348038	2.75E-05	166638	1902	lamin B2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0005638-&&-lamin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0003674-&&-molecular_function	G:9606:LMNB2			KEGG-&-1&-hsa04210-&&-Apoptosis	LMNB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMNB2	0.39471393	0.1453202	31	4	FALSE	LMNB2	LMNB2	275.3103448	0	30	0	0.74441994	FALSE	1	LMNB2	66050	0.09224687
791848	taxon:9606	2.80983142	2.76E-04	182982	1902	4-aminobutyrate aminotransferase	gene	biological_process-&-1&-GO:0035094-&&-response to nicotine-%%-GO:0009450-&&-gamma-aminobutyric acid catabolic process-%%-GO:0021549-&&-cerebellum development-%%-GO:1902722-&&-positive regulation of prolactin secretion-%%-GO:0045964-&&-positive regulation of dopamine metabolic process-%%-GO:0042135-&&-neurotransmitter catabolic process-%%-GO:0007620-&&-copulation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0007568-&&-aging-%%-GO:0009449-&&-gamma-aminobutyric acid biosynthetic process-%%-GO:0031652-&&-positive regulation of heat generation-%%-GO:0045471-&&-response to ethanol-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0010039-&&-response to iron ion-%%-GO:0097151-&&-positive regulation of inhibitory postsynaptic potential-%%-GO:1904450-&&-positive regulation of aspartate secretion-%%-GO:0007626-&&-locomotory behavior-%%-GO:0033602-&&-negative regulation of dopamine secretion-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0042493-&&-response to drug-%%-GO:0035640-&&-exploration behavior-%%-GO:0070474-&&-positive regulation of uterine smooth muscle contraction-%%-GO:0014053-&&-negative regulation of gamma-aminobutyric acid secretion|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0032144-&&-4-aminobutyrate transaminase complex|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0047298-&&-(S)-3-amino-2-methylpropionate transaminase activity-%%-GO:0003867-&&-4-aminobutyrate transaminase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0051536-&&-iron-sulfur cluster binding-%%-GO:0032145-&&-succinate-semialdehyde dehydrogenase binding	G:9606:ABAT	ABAT	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa04727-&&-GABAergic synapse-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00650-&&-Butanoate metabolism	ABAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABAT	0.35589324	0.1182266	31	5	FALSE	ABAT	ABAT	74.75862069	0	30	0	0.69836143	FALSE	1	ABAT	321000	0.05586362
792104	taxon:9606	2.62501969	1.86E-04	182601	1902	collagen type IV alpha 2 chain	gene	biological_process-&-1&-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0001525-&&-angiogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016525-&&-negative regulation of angiogenesis|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005587-&&-collagen type IV trimer-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding	G:9606:COL4A2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	COL4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A2	0.38094952	0.06650246	31	4	FALSE	COL4A2	COL4A2	134.8275862	0	30	0	0.72916338	FALSE	1	COL4A2	171148	0.05618932
792433	taxon:9606	2.51284071	3.01E-05	182029	1902	cleavage stimulation factor subunit 3	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006379-&&-mRNA cleavage|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSTF3			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CSTF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTF3	0.39795598	0.26021505	31	4	FALSE	CSTF3	CSTF3	248.1290323	0	31	0	0.74785988	FALSE	0	CSTF3	66380	0.07911249
792478	taxon:9606	2.69654955	4.54E-05	181959	1902	BCL2 antagonist/killer 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010046-&&-response to mycotoxin-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0010225-&&-response to UV-C-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0009620-&&-response to fungus-%%-GO:0035108-&&-limb morphogenesis-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0060068-&&-vagina development-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0045471-&&-response to ethanol-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0034644-&&-cellular response to UV-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:1902262-&&-apoptotic process involved in blood vessel morphogenesis-%%-GO:0044346-&&-fibroblast apoptotic process-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0042493-&&-response to drug-%%-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0007420-&&-brain development-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0002352-&&-B cell negative selection-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:0007568-&&-aging-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0048597-&&-post-embryonic camera-type eye morphogenesis-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0001782-&&-B cell homeostasis-%%-GO:0019835-&&-cytolysis-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0002262-&&-myeloid cell homeostasis-%%-GO:0042542-&&-response to hydrogen peroxide|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0046930-&&-pore complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0051400-&&-BH domain binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044325-&&-ion channel binding	G:9606:BAK1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05218-&&-Melanoma-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04141-&&-Protein processing in endoplasmic reticulum-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04210-&&-Apoptosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	BAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAK1	0.37084429	0.12807882	31	4	FALSE	BAK1	BAK1	109.137931	0	30	0	0.71724174	FALSE	1	BAK1	54240	0.05427301
792750	taxon:9606	2.50968962	4.96E-05	181443	1902	farnesyl diphosphate synthase	gene	biological_process-&-1&-GO:0045337-&&-farnesyl diphosphate biosynthetic process-%%-GO:0033384-&&-geranyl diphosphate biosynthetic process-%%-GO:0016032-&&-viral process-%%-GO:0006695-&&-cholesterol biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004337-&&-geranyltranstransferase activity-%%-GO:0004161-&&-dimethylallyltranstransferase activity-%%-GO:0046872-&&-metal ion binding	G:9606:FDPS			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05164-&&-Influenza A	FDPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FDPS	0.39845565	0.13978495	31	4	FALSE	FDPS	FDPS	191.0967742	0	31	0	0.74838506	FALSE	0	FDPS	82166	0.06112
792789	taxon:9606	2.55506539	8.99E-05	181360	1902	eukaryotic translation initiation factor 1A, X-linked	gene	biological_process-&-1&-GO:0006413-&&-translational initiation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding	G:9606:EIF1AX			KEGG-&-1&-hsa03013-&&-RNA transport	EIF1AX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF1AX	0.39137942	0.07096774	31	4	FALSE	EIF1AX	EIF1AX	160.8709677	0	31	0	0.74082244	FALSE	0	EIF1AX	113924	0.05681987
792889	taxon:9606	2.8506381	2.21E-04	181214	1902	coagulation factor II, thrombin	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0009611-&&-response to wounding-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006953-&&-acute-phase response-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:1900738-&&-positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0090218-&&-positive regulation of lipid kinase activity-%%-GO:0006465-&&-signal peptide processing-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0042730-&&-fibrinolysis-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030168-&&-platelet activation-%%-GO:0006508-&&-proteolysis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007596-&&-blood coagulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0070053-&&-thrombospondin receptor activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:F2	F2	TRUE	KEGG-&-1&-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04610-&&-Complement and coagulation cascades	F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F2	0.35079865	0.10837438	31	4	FALSE	F2	F2	49.37931034	0	30	0	0.69156032	FALSE	1	F2	192348	0.04435271
793051	taxon:9606	2.61903261	7.18E-05	180831	1902	glutathione-disulfide reductase	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0004362-&&-glutathione-disulfide reductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0050661-&&-NADP binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:GSR	GSR	TRUE	KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa04918-&&-Thyroid hormone synthesis	GSR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSR	0.38182037	0.17980296	31	4	FALSE	GSR	GSR	145.4137931	0	30	0	0.73016123	FALSE	1	GSR	88244	0.0588638
793204	taxon:9606	2.65259178	6.19E-05	180534	1902	hes family bHLH transcription factor 1	gene	biological_process-&-1&-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0061626-&&-pharyngeal arch artery morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0042668-&&-auditory receptor cell fate determination-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045608-&&-negative regulation of auditory receptor cell differentiation-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0007399-&&-nervous system development-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0021537-&&-telencephalon development-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0003266-&&-regulation of secondary heart field cardioblast proliferation-%%-GO:0072049-&&-comma-shaped body morphogenesis-%%-GO:0001889-&&-liver development-%%-GO:0030901-&&-midbrain development-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:2000978-&&-negative regulation of forebrain neuron differentiation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0030324-&&-lung development-%%-GO:0007155-&&-cell adhesion-%%-GO:0003143-&&-embryonic heart tube morphogenesis-%%-GO:0060675-&&-ureteric bud morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0021861-&&-forebrain radial glial cell differentiation-%%-GO:0090102-&&-cochlea development-%%-GO:0016477-&&-cell migration-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0048469-&&-cell maturation-%%-GO:0021555-&&-midbrain-hindbrain boundary morphogenesis-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0048667-&&-cell morphogenesis involved in neuron differentiation-%%-GO:0061309-&&-cardiac neural crest cell development involved in outflow tract morphogenesis-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0072012-&&-glomerulus vasculature development-%%-GO:0045598-&&-regulation of fat cell differentiation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0045977-&&-positive regulation of mitotic cell cycle, embryonic-%%-GO:0072050-&&-S-shaped body morphogenesis-%%-GO:0031016-&&-pancreas development-%%-GO:0021575-&&-hindbrain morphogenesis-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021558-&&-trochlear nerve development-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0061009-&&-common bile duct development-%%-GO:0097084-&&-vascular smooth muscle cell development-%%-GO:0061106-&&-negative regulation of stomach neuroendocrine cell differentiation-%%-GO:0035910-&&-ascending aorta morphogenesis-%%-GO:0003281-&&-ventricular septum development-%%-GO:0072141-&&-renal interstitial fibroblast development-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0060164-&&-regulation of timing of neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060122-&&-inner ear receptor stereocilium organization-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:2000974-&&-negative regulation of pro-B cell differentiation-%%-GO:0021557-&&-oculomotor nerve development-%%-GO:0072282-&&-metanephric nephron tubule morphogenesis-%%-GO:0046331-&&-lateral inhibition-%%-GO:2000227-&&-negative regulation of pancreatic A cell differentiation-%%-GO:0048538-&&-thymus development-%%-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0071820-&&-N-box binding	G:9606:HES1			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05224-&&-Breast cancer-%%-hsa04950-&&-Maturity onset diabetes of the young-%%-hsa05200-&&-Pathways in cancer-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa05165-&&-Human papillomavirus infection	HES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HES1	0.37698978	0.08387097	31	4	FALSE	HES1	HES1	129.5806452	0	31	0	0.72456804	FALSE	0	HES1	73082	0.05817765
793345	taxon:9606	2.73562313	1.34E-04	180261	1902	3-hydroxy-3-methylglutaryl-CoA reductase	gene	biological_process-&-1&-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0061179-&&-negative regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008299-&&-isoprenoid biosynthetic process-%%-GO:0015936-&&-coenzyme A metabolic process-%%-GO:0010664-&&-negative regulation of striated muscle cell apoptotic process-%%-GO:0007568-&&-aging-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0045471-&&-response to ethanol-%%-GO:0008542-&&-visual learning-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0006743-&&-ubiquinone metabolic process-%%-GO:0007584-&&-response to nutrient-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0051262-&&-protein tetramerization-%%-GO:0061045-&&-negative regulation of wound healing|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0004420-&&-hydroxymethylglutaryl-CoA reductase (NADPH) activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070402-&&-NADPH binding-%%-GO:0042282-&&-hydroxymethylglutaryl-CoA reductase activity-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0050662-&&-coenzyme binding	G:9606:HMGCR	HMGCR	TRUE	KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04976-&&-Bile secretion	HMGCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGCR	0.36554743	0.08866995	31	4	FALSE	HMGCR	HMGCR	92.03448276	0	30	0	0.71072948	FALSE	1	HMGCR	132532	0.05308425
793347	taxon:9606	2.68126674	6.35E-05	180257	1902	hyaluronan mediated motility receptor	gene	biological_process-&-1&-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005540-&&-hyaluronic acid binding-%%-GO:0005515-&&-protein binding	G:9606:HMMR			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction	HMMR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMMR	0.37295804	0.09247312	31	4	FALSE	HMMR	HMMR	117.0322581	0	31	0	0.71978888	FALSE	0	HMMR	74774	0.05652574
787190	taxon:9606	2.72380652	5.55E-05	179900	1902	MAF bZIP transcription factor G	gene	biological_process-&-1&-GO:0030534-&&-adult behavior-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030641-&&-regulation of cellular pH-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045604-&&-regulation of epidermal cell differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:MAFG				MAFG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAFG	0.36713327	0.20899471	30	5	FALSE	MAFG	MAFG	110.9285714	0	29	0	0.71269891	FALSE	1	MAFG	57034	0.06017692
787394	taxon:9606	2.67275878	3.69E-05	179507	1902	myocilin	gene	biological_process-&-1&-GO:0038133-&&-ERBB2-ERBB3 signaling pathway-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0038031-&&-non-canonical Wnt signaling pathway via JNK cascade-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0045162-&&-clustering of voltage-gated sodium channels-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0031175-&&-neuron projection development-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0014734-&&-skeletal muscle hypertrophy-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0060348-&&-bone development-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005929-&&-cilium-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0033268-&&-node of Ranvier-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0001968-&&-fibronectin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0032027-&&-myosin light chain binding	G:9606:MYOC				MYOC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOC	0.37414525	0.12962963	30	4	FALSE	MYOC	MYOC	143.1071429	0	29	0	0.72120687	FALSE	1	MYOC	49138	0.06830592
787430	taxon:9606	2.71262014	2.48E-05	163064	1902	aprataxin and PNKP like factor	gene	biological_process-&-1&-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000012-&&-single strand break repair-%%-GO:0051106-&&-positive regulation of DNA ligation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045191-&&-regulation of isotype switching-%%-GO:0006302-&&-double-strand break repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:APLF				APLF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APLF	0.36864727	0.2037037	30	5	FALSE	APLF	APLF	123.4642857	0	29	0	0.71456331	FALSE	1	APLF	39438	0.06501204
787461	taxon:9606	2.79045218	2.97E-05	179393	1902	methyltransferase like 1	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0036265-&&-RNA (guanine-N7)-methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043527-&&-tRNA methyltransferase complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008176-&&-tRNA (guanine-N7-)-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:METTL1				METTL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL1	0.35836486	0.12873563	30	4	FALSE	METTL1	METTL1	77.16666667	0	30	0	0.7015913	FALSE	0	METTL1	33312	0.05420188
787616	taxon:9606	2.77816291	8.33E-05	179085	1902	NK3 homeobox 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007507-&&-heart development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0033574-&&-response to testosterone-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0001656-&&-metanephros development-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0007275-&&-multicellular organism development-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0035690-&&-cellular response to drug-%%-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:2000836-&&-positive regulation of androgen secretion-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0060442-&&-branching involved in prostate gland morphogenesis-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0071899-&&-negative regulation of estrogen receptor binding-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0001756-&&-somitogenesis-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007431-&&-salivary gland development-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0035907-&&-dorsal aorta development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008584-&&-male gonad development-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043569-&&-negative regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004882-&&-androgen receptor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0043621-&&-protein self-association-%%-GO:0097162-&&-MADS box domain binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0030284-&&-estrogen receptor activity-%%-GO:0042826-&&-histone deacetylase binding	G:9606:NKX3-1	NKX3-1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05200-&&-Pathways in cancer	NKX3-1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKX3-1	0.35995009	0.02988506	30	4	FALSE	NKX3-1	NKX3-1	80.03333333	0	30	0	0.70363951	FALSE	0	NKX3-1	94318	0.05354419
787744	taxon:9606	2.71640145	2.37E-05	178851	1902	RNA polymerase II subunit L	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0005515-&&-protein binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR2L			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2L	0.3681341	0.28735632	30	4	FALSE	POLR2L	POLR2L	105.1333333	0	30	0	0.71393309	FALSE	0	POLR2L	34840	0.05606546
787783	taxon:9606	2.68347251	2.81E-05	178792	1902	palmitoyl-protein thioesterase 1	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0015031-&&-protein transport-%%-GO:0006907-&&-pinocytosis-%%-GO:0008306-&&-associative learning-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048666-&&-neuron development-%%-GO:0051186-&&-cofactor metabolic process-%%-GO:0050896-&&-response to stimulus-%%-GO:0031579-&&-membrane raft organization-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0050803-&&-regulation of synapse structure or activity-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0048549-&&-positive regulation of pinocytosis-%%-GO:0002084-&&-protein depalmitoylation-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007625-&&-grooming behavior-%%-GO:0051181-&&-cofactor transport-%%-GO:0030149-&&-sphingolipid catabolic process-%%-GO:0007042-&&-lysosomal lumen acidification-%%-GO:0007399-&&-nervous system development-%%-GO:0007420-&&-brain development-%%-GO:0030163-&&-protein catabolic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0007601-&&-visual perception-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0032429-&&-regulation of phospholipase A2 activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0030424-&&-axon-%%-GO:0005615-&&-extracellular space-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0005829-&&-cytosol-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016290-&&-palmitoyl-CoA hydrolase activity-%%-GO:0008474-&&-palmitoyl-(protein) hydrolase activity	G:9606:PPT1			KEGG-&-1&-hsa00062-&&-Fatty acid elongation-%%-hsa01100-&&-Metabolic pathways-%%-hsa04142-&&-Lysosome-%%-hsa01212-&&-Fatty acid metabolism	PPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPT1	0.37265148	0.09425287	30	4	FALSE	PPT1	PPT1	121.4	0	30	0	0.71942125	FALSE	0	PPT1	42888	0.05916341
788013	taxon:9606	2.71466835	3.53E-05	178398	1902	prefoldin subunit 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016272-&&-prefoldin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:PFDN4				PFDN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFDN4	0.36836912	0.13333333	30	4	FALSE	PFDN4	PFDN4	109.7666667	0	30	0	0.71422194	FALSE	0	PFDN4	47740	0.05881617
788017	taxon:9606	2.65211911	1.59E-05	178394	1902	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	gene	biological_process-&-1&-GO:0006089-&&-lactate metabolic process-%%-GO:0033133-&&-positive regulation of glucokinase activity-%%-GO:0006003-&&-fructose 2,6-bisphosphate metabolic process-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0006096-&&-glycolytic process-%%-GO:0009749-&&-response to glucose-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0016311-&&-dephosphorylation-%%-GO:0032024-&&-positive regulation of insulin secretion|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004331-&&-fructose-2,6-bisphosphate 2-phosphatase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003873-&&-6-phosphofructo-2-kinase activity	G:9606:PFKFB2			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04152-&&-AMPK signaling pathway	PFKFB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKFB2	0.37705697	0.37011494	30	4	FALSE	PFKFB2	PFKFB2	261.5333333	0	30	0	0.72464681	FALSE	0	PFKFB2	43918	0.11593496
788035	taxon:9606	2.71608634	2.16E-05	178330	1902	RAR related orphan receptor A	gene	biological_process-&-1&-GO:0042692-&&-muscle cell differentiation-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0021930-&&-cerebellar granule cell precursor proliferation-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0019218-&&-regulation of steroid metabolic process-%%-GO:0046068-&&-cGMP metabolic process-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0036315-&&-cellular response to sterol-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021702-&&-cerebellar Purkinje cell differentiation-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0001525-&&-angiogenesis-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0072539-&&-T-helper 17 cell differentiation-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0043030-&&-regulation of macrophage activation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001222-&&-transcription corepressor binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008142-&&-oxysterol binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0098531-&&-transcription factor activity, direct ligand regulated sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	G:9606:RORA			KEGG-&-1&-hsa04710-&&-Circadian rhythm-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04659-&&-Th17 cell differentiation	RORA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RORA	0.36817681	0.06878307	30	4	FALSE	RORA	RORA	125.5714286	0	29	0	0.71398561	FALSE	1	RORA	39554	0.06620255
788036	taxon:9606	2.7726485	3.65E-05	178324	1902	retinitis pigmentosa 2 (X-linked recessive)	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0007023-&&-post-chaperonin tubulin folding pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007601-&&-visual perception-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:1990075-&&-periciliary membrane compartment-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005929-&&-cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005814-&&-centriole-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0051082-&&-unfolded protein binding	G:9606:RP2				RP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RP2	0.36066598	0.02528736	30	4	FALSE	RP2	RP2	77.86666667	0	30	0	0.70455858	FALSE	0	RP2	39870	0.05114638
788119	taxon:9606	2.67590988	2.97E-05	178211	1902	protein tyrosine phosphatase, non-receptor type 13	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding	G:9606:PTPN13			KEGG-&-1&-hsa04210-&&-Apoptosis	PTPN13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN13	0.37370466	0.08505747	30	4	FALSE	PTPN13	PTPN13	123.6	0	30	0	0.72068169	FALSE	0	PTPN13	49200	0.05907133
788134	taxon:9606	2.50874429	1.78E-05	178187	1902	purine rich element binding protein A	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0006268-&&-DNA unwinding involved in DNA replication-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0032422-&&-purine-rich negative regulatory element binding-%%-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003723-&&-RNA binding-%%-GO:0000900-&&-translation repressor activity, nucleic acid binding	G:9606:PURA				PURA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PURA	0.39860579	0.22758621	30	4	FALSE	PURA	PURA	271.5	0	30	0	0.74854262	FALSE	0	PURA	49272	0.08652641
788139	taxon:9606	2.58484323	7.00E-05	178169	1902	glycogen phosphorylase B	gene	biological_process-&-1&-GO:0005980-&&-glycogen catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0008184-&&-glycogen phosphorylase activity	G:9606:PYGB			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa04217-&&-Necroptosis	PYGB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYGB	0.38687066	0.11904762	30	4	FALSE	PYGB	PYGB	194.4285714	0	29	0	0.73585946	FALSE	1	PYGB	92408	0.07218506
788231	taxon:9606	2.6351032	3.65E-05	178037	1902	SH3 domain binding protein 2	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:SH3BP2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity	SH3BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3BP2	0.37949178	0.32183908	30	4	FALSE	SH3BP2	SH3BP2	157.6	0	30	0	0.7274828	FALSE	0	SH3BP2	54954	0.06746575
788243	taxon:9606	2.68221207	2.88E-05	161634	1902	WD repeat domain 62	gene	biological_process-&-1&-GO:0021987-&&-cerebral cortex development-%%-GO:0022008-&&-neurogenesis-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0007099-&&-centriole replication-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071011-&&-precatalytic spliceosome-%%-GO:0000922-&&-spindle pole-%%-GO:0005814-&&-centriole-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005813-&&-centrosome-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WDR62				WDR62	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR62	0.3728266	0.1031746	30	4	FALSE	WDR62	WDR62	145.4642857	0	29	0	0.71963132	FALSE	1	WDR62	45568	0.06946437
788316	taxon:9606	2.53032929	1.01E-04	177902	1902	S100 calcium binding protein A7	gene	biological_process-&-1&-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0071624-&&-positive regulation of granulocyte chemotaxis-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0008544-&&-epidermis development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051238-&&-sequestering of metal ion-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001525-&&-angiogenesis-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005925-&&-focal adhesion-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:S100A7			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	S100A7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A7	0.39520548	0.10582011	30	4	FALSE	S100A7	S100A7	205.7142857	0	29	0	0.74494512	FALSE	1	S100A7	107700	0.06856761
788543	taxon:9606	2.64046006	5.11E-05	177466	1902	sorcin	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007507-&&-heart development-%%-GO:0006942-&&-regulation of striated muscle contraction-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0006816-&&-calcium ion transport-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0001508-&&-action potential-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:1901841-&&-regulation of high voltage-gated calcium channel activity-%%-GO:1901844-&&-regulation of cell communication by electrical coupling involved in cardiac conduction-%%-GO:0006810-&&-transport-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:1901077-&&-regulation of relaxation of muscle-%%-GO:0010459-&&-negative regulation of heart rate-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0006880-&&-intracellular sequestering of iron ion-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0010649-&&-regulation of cell communication by electrical coupling-%%-GO:0007517-&&-muscle organ development-%%-GO:0007165-&&-signal transduction-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0051924-&&-regulation of calcium ion transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0044326-&&-dendritic spine neck-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0042584-&&-chromaffin granule membrane-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030424-&&-axon-%%-GO:0043679-&&-axon terminus-%%-GO:0030315-&&-T-tubule|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0044325-&&-ion channel binding	G:9606:SRI				SRI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRI	0.37872188	0.0952381	30	4	FALSE	SRI	SRI	152.7142857	0	29	0	0.72658999	FALSE	1	SRI	70978	0.06612723
788886	taxon:9606	2.60044115	7.79E-05	176679	1902	Wilms tumor 1	gene	biological_process-&-1&-GO:0009888-&&-tissue development-%%-GO:0030325-&&-adrenal gland development-%%-GO:0032836-&&-glomerular basement membrane development-%%-GO:0072112-&&-glomerular visceral epithelial cell differentiation-%%-GO:0072166-&&-posterior mesonephric tubule development-%%-GO:0061032-&&-visceral serous pericardium development-%%-GO:0001822-&&-kidney development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0035802-&&-adrenal cortex formation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060923-&&-cardiac muscle cell fate commitment-%%-GO:0071371-&&-cellular response to gonadotropin stimulus-%%-GO:0008584-&&-male gonad development-%%-GO:2000195-&&-negative regulation of female gonad development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0072302-&&-negative regulation of metanephric glomerular mesangial cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0003156-&&-regulation of animal organ formation-%%-GO:0060539-&&-diaphragm development-%%-GO:2001076-&&-positive regulation of metanephric ureteric bud development-%%-GO:0060421-&&-positive regulation of heart growth-%%-GO:0008406-&&-gonad development-%%-GO:0001657-&&-ureteric bud development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007281-&&-germ cell development-%%-GO:0043010-&&-camera-type eye development-%%-GO:0072284-&&-metanephric S-shaped body morphogenesis-%%-GO:0030539-&&-male genitalia development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007356-&&-thorax and anterior abdomen determination-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0001570-&&-vasculogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0072207-&&-metanephric epithelium development-%%-GO:0007507-&&-heart development-%%-GO:0032835-&&-glomerulus development-%%-GO:0072075-&&-metanephric mesenchyme development-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008380-&&-RNA splicing-%%-GO:0007530-&&-sex determination-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:2000020-&&-positive regulation of male gonad development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044729-&&-hemi-methylated DNA-binding-%%-GO:0070742-&&-C2H2 zinc finger domain binding-%%-GO:0010385-&&-double-stranded methylated DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:WT1	WT1	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	WT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WT1	0.38455014	0.08735632	30	4	FALSE	WT1	WT1	157.4333333	0	30	0	0.73325981	FALSE	0	WT1	104660	0.0616562
788965	taxon:9606	2.54655743	6.77E-05	176516	1902	sperm associated antigen 9	gene	biological_process-&-1&-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0090074-&&-negative regulation of protein homodimerization activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0051149-&&-positive regulation of muscle cell differentiation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0019894-&&-kinesin binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0008432-&&-JUN kinase binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0048273-&&-mitogen-activated protein kinase p38 binding	G:9606:SPAG9				SPAG9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPAG9	0.392687	0.1031746	30	4	FALSE	SPAG9	SPAG9	200.1071429	0	29	0	0.74224043	FALSE	1	SPAG9	87576	0.0684096
789037	taxon:9606	2.71214747	4.24E-05	176312	1902	axin 2	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0032423-&&-regulation of mismatch repair-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0001756-&&-somitogenesis-%%-GO:0030282-&&-bone mineralization-%%-GO:0061181-&&-regulation of chondrocyte development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0001957-&&-intramembranous ossification-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0070602-&&-regulation of centromeric sister chromatid cohesion-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:1904837-&&-beta-catenin-TCF complex assembly-%%-GO:0008283-&&-cell proliferation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0042476-&&-odontogenesis-%%-GO:0003413-&&-chondrocyte differentiation involved in endochondral bone morphogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0034613-&&-cellular protein localization-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0070411-&&-I-SMAD binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AXIN2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04934-&&-Cushing syndrome-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer-%%-hsa05165-&&-Human papillomavirus infection	AXIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AXIN2	0.36871151	0.14942529	30	4	FALSE	AXIN2	AXIN2	112.5333333	0	30	0	0.71464209	FALSE	0	AXIN2	59976	0.05931398
789039	taxon:9606	2.55868914	4.15E-05	176309	1902	cell division cycle 7	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0006260-&&-DNA replication-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0000727-&&-double-strand break repair via break-induced replication-%%-GO:0010571-&&-positive regulation of nuclear cell cycle DNA replication-%%-GO:0051301-&&-cell division-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006909-&&-phagocytosis|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:CDC7			KEGG-&-1&-hsa04110-&&-Cell cycle	CDC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC7	0.39082512	0.20899471	30	4	FALSE	CDC7	CDC7	186.8928571	0	29	0	0.74021848	FALSE	1	CDC7	57020	0.06548036
789074	taxon:9606	2.77154561	2.17E-04	176246	1902	neuropilin 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0061299-&&-retina vasculature morphogenesis in camera-type eye-%%-GO:1902336-&&-positive regulation of retinal ganglion cell axon guidance-%%-GO:1902946-&&-protein localization to early endosome-%%-GO:0060978-&&-angiogenesis involved in coronary vascular morphogenesis-%%-GO:0036486-&&-ventral trunk neural crest cell migration-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0038190-&&-VEGF-activated neuropilin signaling pathway-%%-GO:0097490-&&-sympathetic neuron projection extension-%%-GO:1901166-&&-neural crest cell migration involved in autonomic nervous system development-%%-GO:1904835-&&-dorsal root ganglion morphogenesis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0097491-&&-sympathetic neuron projection guidance-%%-GO:0021637-&&-trigeminal nerve structural organization-%%-GO:0060301-&&-positive regulation of cytokine activity-%%-GO:0060666-&&-dichotomous subdivision of terminal units involved in salivary gland branching-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0090259-&&-regulation of retinal ganglion cell axon guidance-%%-GO:0001525-&&-angiogenesis-%%-GO:0021612-&&-facial nerve structural organization-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0061441-&&-renal artery morphogenesis-%%-GO:0009611-&&-response to wounding-%%-GO:1902287-&&-semaphorin-plexin signaling pathway involved in axon guidance-%%-GO:0001764-&&-neuron migration-%%-GO:0007411-&&-axon guidance-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0021785-&&-branchiomotor neuron axon guidance-%%-GO:0007165-&&-signal transduction-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0060385-&&-axonogenesis involved in innervation-%%-GO:0007413-&&-axonal fasciculation-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0021828-&&-gonadotrophin-releasing hormone neuronal migration to the hypothalamus-%%-GO:1901998-&&-toxin transport-%%-GO:0021675-&&-nerve development-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0016358-&&-dendrite development-%%-GO:0048843-&&-negative regulation of axon extension involved in axon guidance-%%-GO:0048842-&&-positive regulation of axon extension involved in axon guidance-%%-GO:0097102-&&-endothelial tip cell fate specification-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0021649-&&-vestibulocochlear nerve structural organization-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:1903375-&&-facioacoustic ganglion development-%%-GO:0061551-&&-trigeminal ganglion development-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0048846-&&-axon extension involved in axon guidance-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0097374-&&-sensory neuron axon guidance-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0060627-&&-regulation of vesicle-mediated transport-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:1902285-&&-semaphorin-plexin signaling pathway involved in neuron projection guidance-%%-GO:0071679-&&-commissural neuron axon guidance-%%-GO:1902378-&&-VEGF-activated neuropilin signaling pathway involved in axon guidance-%%-GO:1905040-&&-otic placode development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005769-&&-early endosome-%%-GO:0043025-&&-neuronal cell body-%%-GO:0097443-&&-sorting endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0002116-&&-semaphorin receptor complex-%%-GO:0030426-&&-growth cone-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030424-&&-axon-%%-GO:0005883-&&-neurofilament-%%-GO:0005829-&&-cytosol-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0015026-&&-coreceptor activity-%%-GO:0038085-&&-vascular endothelial growth factor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0019955-&&-cytokine binding-%%-GO:0017154-&&-semaphorin receptor activity	G:9606:NRP1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	NRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRP1	0.3608095	0.07407407	30	4	FALSE	NRP1	NRP1	76.35714286	0	29	0	0.7047424	FALSE	1	NRP1	243506	0.05033969
789241	taxon:9606	2.68536316	5.72E-05	175922	1902	proteasome assembly chaperone 1	gene	biological_process-&-1&-GO:0021930-&&-cerebellar granule cell precursor proliferation-%%-GO:0043248-&&-proteasome assembly-%%-GO:0080129-&&-proteasome core complex assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0070628-&&-proteasome binding-%%-GO:0005515-&&-protein binding	G:9606:PSMG1				PSMG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMG1	0.37238911	0.2037037	30	4	FALSE	PSMG1	PSMG1	136.1785714	0	29	0	0.71910614	FALSE	1	PSMG1	70850	0.06592608
789261	taxon:9606	2.57775327	2.25E-05	175881	1902	eukaryotic translation initiation factor 4 gamma 3	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0006413-&&-translational initiation-%%-GO:0016032-&&-viral process-%%-GO:0010507-&&-negative regulation of autophagy|cellular_component-&-1&-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003743-&&-translation initiation factor activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0000339-&&-RNA cap binding	G:9606:EIF4G3			KEGG-&-1&-hsa05416-&&-Viral myocarditis-%%-hsa03013-&&-RNA transport	EIF4G3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4G3	0.38793472	0.2045977	30	4	FALSE	EIF4G3	EIF4G3	179.9666667	0	30	0	0.73704112	FALSE	0	EIF4G3	42978	0.06559728
789304	taxon:9606	2.47991177	7.63E-05	175790	1902	glutathione S-transferase omega 1	gene	biological_process-&-1&-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0060316-&&-positive regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019852-&&-L-ascorbic acid metabolic process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0032259-&&-methylation-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0014810-&&-positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion-%%-GO:0071243-&&-cellular response to arsenic-containing substance|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0045174-&&-glutathione dehydrogenase (ascorbate) activity-%%-GO:0005515-&&-protein binding-%%-GO:0050610-&&-methylarsonate reductase activity	G:9606:GSTO1			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05204-&&-Chemical carcinogenesis	GSTO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTO1	0.40324015	0.11494253	30	4	FALSE	GSTO1	GSTO1	203.4333333	0	30	0	0.75334804	FALSE	0	GSTO1	105646	0.06147723
789824	taxon:9606	2.63132188	2.23E-05	174559	1902	bromodomain containing 8	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000812-&&-Swr1 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:BRD8				BRD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD8	0.38003712	0.22988506	30	4	FALSE	BRD8	BRD8	171.2666667	0	30	0	0.72811302	FALSE	0	BRD8	53282	0.07064081
790051	taxon:9606	2.46904049	8.09E-05	173996	1902	kinesin family member 3A	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0022008-&&-neurogenesis-%%-GO:0034454-&&-microtubule anchoring at centrosome-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0010457-&&-centriole-centriole cohesion-%%-GO:0072383-&&-plus-end-directed vesicle transport along microtubule-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0060271-&&-cilium assembly-%%-GO:0006996-&&-organelle organization-%%-GO:0007018-&&-microtubule-based movement|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0016939-&&-kinesin II complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0097542-&&-ciliary tip-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0030507-&&-spectrin binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:KIF3A			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway	KIF3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF3A	0.40501563	0.10344828	30	4	FALSE	KIF3A	KIF3A	208.8	0	30	0	0.75515992	FALSE	0	KIF3A	104074	0.06178067
790153	taxon:9606	2.49519458	1.90E-05	173752	1902	programmed cell death 11	gene	biological_process-&-1&-GO:0006397-&&-mRNA processing-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PDCD11				PDCD11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD11	0.40077035	0.18390805	30	4	FALSE	PDCD11	PDCD11	360.1	0	30	0	0.7508009	FALSE	0	PDCD11	68128	0.11192993
790231	taxon:9606	2.58909721	5.90E-05	173575	1902	exocyst complex component 7	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:0006887-&&-exocytosis-%%-GO:2000535-&&-regulation of entry of bacterium into host cell|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0005829-&&-cytosol-%%-GO:0032584-&&-growth cone membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016020-&&-membrane-%%-GO:0000145-&&-exocyst|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EXOC7			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	EXOC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC7	0.38623501	0.18390805	30	4	FALSE	EXOC7	EXOC7	150.6666667	0	30	0	0.73515046	FALSE	0	EXOC7	76826	0.05693026
790271	taxon:9606	2.77532693	1.03E-04	173470	1902	ATPase 13A2	gene	biological_process-&-1&-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0033157-&&-regulation of intracellular protein transport-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1905122-&&-polyamine import-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:1905123-&&-regulation of glucosylceramidase activity-%%-GO:0016243-&&-regulation of autophagosome size-%%-GO:0052548-&&-regulation of endopeptidase activity-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1905037-&&-autophagosome organization-%%-GO:1990938-&&-peptidyl-aspartic acid autophosphorylation-%%-GO:0030003-&&-cellular cation homeostasis-%%-GO:1905165-&&-regulation of lysosomal protein catabolic process-%%-GO:1905166-&&-negative regulation of lysosomal protein catabolic process-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0055069-&&-zinc ion homeostasis-%%-GO:0071294-&&-cellular response to zinc ion-%%-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031982-&&-vesicle-%%-GO:0032585-&&-multivesicular body membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0043005-&&-neuron projection-%%-GO:0005770-&&-late endosome-%%-GO:0005776-&&-autophagosome-%%-GO:1905103-&&-integral component of lysosomal membrane-%%-GO:0012506-&&-vesicle membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005771-&&-multivesicular body-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0019829-&&-cation-transporting ATPase activity-%%-GO:0005515-&&-protein binding-%%-GO:1903135-&&-cupric ion binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0005524-&&-ATP binding-%%-GO:0070300-&&-phosphatidic acid binding	G:9606:ATP13A2	ATP13A2	TRUE		ATP13A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP13A2	0.36031791	0.02298851	30	4	FALSE	ATP13A2	ATP13A2	70.96666667	0	30	0	0.70411218	FALSE	0	ATP13A2	100298	0.04877485
790460	taxon:9606	2.64282338	3.40E-05	172795	1902	SS18L1, nBAF chromatin remodeling complex subunit	gene	biological_process-&-1&-GO:0016358-&&-dendrite development-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0016604-&&-nuclear body-%%-GO:0071565-&&-nBAF complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:SS18L1				SS18L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SS18L1	0.37838321	0.17195767	30	4	FALSE	SS18L1	SS18L1	166.6071429	0	29	0	0.7261961	FALSE	1	SS18L1	53536	0.07209367
790529	taxon:9606	2.74428864	5.33E-05	172588	1902	LSM1 homolog, mRNA degradation associated	gene	biological_process-&-1&-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0008380-&&-RNA splicing-%%-GO:0000290-&&-deadenylation-dependent decapping of nuclear-transcribed mRNA-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0006397-&&-mRNA processing-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:1990124-&&-messenger ribonucleoprotein complex-%%-GO:0030425-&&-dendrite-%%-GO:0030424-&&-axon-%%-GO:0000932-&&-P-body-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0036002-&&-pre-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000339-&&-RNA cap binding-%%-GO:0003723-&&-RNA binding	G:9606:LSM1			KEGG-&-1&-hsa03018-&&-RNA degradation	LSM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM1	0.36439316	0.08045977	30	4	FALSE	LSM1	LSM1	95.66666667	0	30	0	0.70928523	FALSE	0	LSM1	65632	0.0554586
790572	taxon:9606	2.56609422	7.03E-05	172100	1902	tRNA methyltransferase 2 homolog A	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0001510-&&-RNA methylation|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008173-&&-RNA methyltransferase activity	G:9606:TRMT2A				TRMT2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT2A	0.3896973	0.05747126	30	4	FALSE	TRMT2A	TRMT2A	154.6	0	30	0	0.7389843	FALSE	0	TRMT2A	95302	0.05553156
790647	taxon:9606	2.63069167	5.52E-05	171675	1902	G protein nucleolar 3 like	gene	biological_process-&-1&-GO:1904816-&&-positive regulation of protein localization to chromosome, telomeric region-%%-GO:0032211-&&-negative regulation of telomere maintenance via telomerase-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0090073-&&-positive regulation of protein homodimerization activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:GNL3L			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GNL3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNL3L	0.38012817	0.08505747	30	4	FALSE	GNL3L	GNL3L	164.1666667	0	30	0	0.72821806	FALSE	0	GNL3L	85542	0.06857661
790699	taxon:9606	2.53458327	3.44E-05	171435	1902	SUMO1/sentrin specific peptidase 1	gene	biological_process-&-1&-GO:0016926-&&-protein desumoylation-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006508-&&-proteolysis-%%-GO:0016925-&&-protein sumoylation-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070139-&&-SUMO-specific endopeptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0016929-&&-SUMO-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:SENP1				SENP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SENP1	0.39454218	0.20899471	30	4	FALSE	SENP1	SENP1	206.5	0	29	0	0.74423612	FALSE	1	SENP1	56106	0.06943443
790700	taxon:9606	2.62596502	4.04E-05	171434	1902	TCF3 fusion partner	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006310-&&-DNA recombination-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031011-&&-Ino80 complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:TFPT				TFPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFPT	0.38081238	0.12433862	30	4	FALSE	TFPT	TFPT	129.1428571	0	29	0	0.72900583	FALSE	1	TFPT	53652	0.05348996
790706	taxon:9606	2.47061604	2.18E-05	171423	1902	G protein nucleolar 2	gene	biological_process-&-1&-GO:0042254-&&-ribosome biogenesis-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding	G:9606:GNL2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	GNL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNL2	0.40475735	0.32183908	30	4	FALSE	GNL2	GNL2	302.7	0	30	0	0.75489733	FALSE	0	GNL2	48944	0.08970559
790819	taxon:9606	2.72947849	1.88E-05	171108	1902	deleted in esophageal cancer 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation	G:9606:DEC1				1-Dec	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEC1	0.36637035	0.36243386	30	4	FALSE	1-Dec	1-Dec	132.5357143	0	29	0	0.71175358	FALSE	1	1-Dec	34618	0.07250313
790823	taxon:9606	2.59146053	2.10E-05	171079	1902	DDB1 and CUL4 associated factor 8	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DCAF8				DCAF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF8	0.38588278	0.2091954	30	4	FALSE	DCAF8	DCAF8	175.9333333	0	30	0	0.73475658	FALSE	0	DCAF8	43056	0.06692035
790878	taxon:9606	2.62517725	4.29E-05	170795	1902	glyoxalase domain containing 4	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0045296-&&-cadherin binding	G:9606:GLOD4				GLOD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLOD4	0.38092666	0.1816092	30	4	FALSE	GLOD4	GLOD4	136.2333333	0	30	0	0.72913713	FALSE	0	GLOD4	66224	0.05638371
790949	taxon:9606	2.68284229	4.95E-05	170630	1902	calcium binding protein 39	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0007050-&&-cell cycle arrest-%%-GO:2000687-&&-negative regulation of rubidium ion transmembrane transporter activity-%%-GO:0071476-&&-cellular hypotonic response-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:2000681-&&-negative regulation of rubidium ion transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:1902554-&&-serine/threonine protein kinase complex-%%-GO:0043234-&&-protein complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity	G:9606:CAB39			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	CAB39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAB39	0.37273902	0.05977011	30	4	FALSE	CAB39	CAB39	107.3	0	30	0	0.71952629	FALSE	0	CAB39	55720	0.05246732
791289	taxon:9606	2.55475028	9.20E-05	169323	1902	VPS18, CORVET/HOPS core subunit	gene	biological_process-&-1&-GO:0007040-&&-lysosome organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0007032-&&-endosome organization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006914-&&-autophagy-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0035542-&&-regulation of SNARE complex assembly-%%-GO:0008333-&&-endosome to lysosome transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031902-&&-late endosome membrane-%%-GO:0030897-&&-HOPS complex-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0030123-&&-AP-3 adaptor complex-%%-GO:0033263-&&-CORVET complex-%%-GO:0005884-&&-actin filament-%%-GO:0005769-&&-early endosome-%%-GO:0005776-&&-autophagosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019905-&&-syntaxin binding	G:9606:VPS18				VPS18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS18	0.39142769	0.07142857	30	4	FALSE	VPS18	VPS18	154.6785714	0	29	0	0.74087495	FALSE	1	VPS18	99848	0.05392059
791330	taxon:9606	2.77170317	3.36E-05	169130	1902	p21 (RAC1) activated kinase 5	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0016477-&&-cell migration-%%-GO:0007613-&&-memory-%%-GO:0007612-&&-learning-%%-GO:0008283-&&-cell proliferation-%%-GO:0016049-&&-cell growth-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PAK5			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	PAK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK5	0.36078899	0.03968254	30	4	FALSE	PAK5	PAK5	81.17857143	0	29	0	0.70471614	FALSE	1	PAK5	40146	0.05321852
791348	taxon:9606	2.62817079	7.05E-05	169066	1902	RAD50 interactor 1	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0060628-&&-regulation of ER to Golgi vesicle-mediated transport-%%-GO:1902504-&&-regulation of signal transduction involved in mitotic G2 DNA damage checkpoint-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070939-&&-Dsl1/NZR complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RINT1				RINT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RINT1	0.38049278	0.07586207	30	4	FALSE	RINT1	RINT1	125.6333333	0	30	0	0.7286382	FALSE	0	RINT1	81142	0.05246862
791361	taxon:9606	2.48589885	1.10E-04	168981	1902	PBX homeobox interacting protein 1	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development-%%-GO:0030154-&&-cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:PBXIP1				PBXIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PBXIP1	0.40226898	0.06896552	30	4	FALSE	PBXIP1	PBXIP1	202.2	0	30	0	0.75235019	FALSE	0	PBXIP1	148836	0.06180853
791755	taxon:9606	2.85016543	6.06E-05	167020	1902	transmembrane protein 185A	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TMEM185A				TMEM185A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM185A	0.35085683	0.03448276	30	5	FALSE	TMEM185A	TMEM185A	61	0	30	0	0.69163909	FALSE	0	TMEM185A	58822	0.0564461
791921	taxon:9606	2.72947849	4.36E-06	166491	1902	histone cluster 1 H2B family member k	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0000786-&&-nucleosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BK			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BK	0.36637035	0.32873563	30	4	FALSE	HIST1H2BK	HIST1H2BK	235.0666667	0	30	0	0.71175358	FALSE	0	HIST1H2BK	19896	0.1285558
792214	taxon:9606	2.69576178	3.38E-05	182402	1902	activating transcription factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032025-&&-response to cobalt ion-%%-GO:0045740-&&-positive regulation of DNA replication|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:1990590-&&-ATF1-ATF4 transcription factor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:ATF1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04925-&&-Aldosterone synthesis and secretion	ATF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF1	0.37095266	0.1957672	30	5	FALSE	ATF1	ATF1	126.5357143	0	29	0	0.71737304	FALSE	1	ATF1	46484	0.06308811
792237	taxon:9606	2.66629904	6.52E-05	182371	1902	aldehyde dehydrogenase 7 family member A1	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0006554-&&-lysine catabolic process-%%-GO:0042426-&&-choline catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019285-&&-glycine betaine biosynthetic process from choline|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004043-&&-L-aminoadipate-semialdehyde dehydrogenase activity-%%-GO:0008802-&&-betaine-aldehyde dehydrogenase activity-%%-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity-%%-GO:0005515-&&-protein binding	G:9606:ALDH7A1			KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa00340-&&-Histidine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	ALDH7A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH7A1	0.3750517	0.14942529	30	4	FALSE	ALDH7A1	ALDH7A1	122.7333333	0	30	0	0.72228349	FALSE	0	ALDH7A1	78466	0.05668672
792251	taxon:9606	2.60910666	3.26E-05	165967	1902	HAUS augmin like complex subunit 8	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:HAUS8				HAUS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS8	0.38327295	0.38390805	30	4	FALSE	HAUS8	HAUS8	155.5666667	0	30	0	0.73181556	FALSE	0	HAUS8	64590	0.06138966
792301	taxon:9606	2.65337955	2.75E-05	182257	1902	CCAAT/enhancer binding protein delta	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048839-&&-inner ear development-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CEBPD				CEBPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPD	0.37687786	0.27777778	30	4	FALSE	CEBPD	CEBPD	170.9285714	0	29	0	0.72443674	FALSE	1	CEBPD	48772	0.07546515
792394	taxon:9606	2.78556798	1.31E-04	182096	1902	C-reactive protein	gene	biological_process-&-1&-GO:0006953-&&-acute-phase response-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:2000482-&&-regulation of interleukin-8 secretion-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0006954-&&-inflammatory response-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0008228-&&-opsonization|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0046790-&&-virion binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0033265-&&-choline binding-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CRP	CRP	TRUE		CRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRP	0.35899321	0.04232804	30	5	FALSE	CRP	CRP	82.85714286	0	29	0	0.70240534	FALSE	1	CRP	158636	0.05691579
792505	taxon:9606	2.68678116	2.96E-05	181895	1902	carbonic anhydrase 9	gene	biological_process-&-1&-GO:0006730-&&-one-carbon metabolic process-%%-GO:0046903-&&-secretion-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0033574-&&-response to testosterone-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0031528-&&-microvillus membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004089-&&-carbonate dehydratase activity	G:9606:CA9			KEGG-&-1&-hsa00910-&&-Nitrogen metabolism	CA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CA9	0.37219258	0.08045977	30	4	FALSE	CA9	CA9	120.0666667	0	30	0	0.71886981	FALSE	0	CA9	44178	0.05809478
792687	taxon:9606	2.50496297	8.17E-05	181562	1902	doublecortin	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0001764-&&-neuron migration-%%-GO:0007417-&&-central nervous system development-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:DCX				DCX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCX	0.3992075	0.07407407	30	4	FALSE	DCX	DCX	190.6428571	0	29	0	0.74917284	FALSE	1	DCX	112020	0.06030389
792745	taxon:9606	2.73751379	1.08E-04	181454	1902	Fc fragment of IgG receptor IIa	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019864-&&-IgG binding	G:9606:FCGR2A			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04611-&&-Platelet activation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05150-&&-Staphylococcus aureus infection	FCGR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCGR2A	0.36529496	0.10804598	30	4	FALSE	FCGR2A	FCGR2A	97.56666667	0	30	0	0.71041437	FALSE	0	FCGR2A	110460	0.05709532
792786	taxon:9606	2.61934772	3.48E-05	181365	1902	early growth response 1	gene	biological_process-&-1&-GO:0071504-&&-cellular response to heparin-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0002931-&&-response to ischemia-%%-GO:0032868-&&-response to insulin-%%-GO:0030217-&&-T cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072303-&&-positive regulation of glomerular metanephric mesangial cell proliferation-%%-GO:0046886-&&-positive regulation of hormone biosynthetic process-%%-GO:0033233-&&-regulation of protein sumoylation-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0072110-&&-glomerular mesangial cell proliferation-%%-GO:0071506-&&-cellular response to mycophenolic acid-%%-GO:0009749-&&-response to glucose-%%-GO:0050725-&&-positive regulation of interleukin-1 beta biosynthetic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:2000182-&&-regulation of progesterone biosynthetic process-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0098759-&&-cellular response to interleukin-8-%%-GO:0044849-&&-estrous cycle-%%-GO:0071480-&&-cellular response to gamma radiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0044729-&&-hemi-methylated DNA-binding-%%-GO:0003677-&&-DNA binding-%%-GO:0010385-&&-double-stranded methylated DNA binding	G:9606:EGR1			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa04912-&&-GnRH signaling pathway	EGR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGR1	0.38177444	0.2	30	4	FALSE	EGR1	EGR1	170.0666667	0	30	0	0.73010871	FALSE	0	EGR1	55194	0.06964359
792879	taxon:9606	2.67890342	2.84E-05	181232	1902	MDS1 and EVI1 complex locus	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0071425-&&-hematopoietic stem cell proliferation-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0051726-&&-regulation of cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:MECOM			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05220-&&-Chronic myeloid leukemia	MECOM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MECOM	0.37328707	0.25057471	30	4	FALSE	MECOM	MECOM	154	0	30	0	0.72018276	FALSE	0	MECOM	41174	0.0721519
793021	taxon:9606	2.81187963	1.26E-05	180882	1902	glutathione peroxidase 4	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0047066-&&-phospholipid-hydroperoxide glutathione peroxidase activity	G:9606:GPX4			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa04216-&&-Ferroptosis	GPX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPX4	0.355634	0.28735632	30	4	FALSE	GPX4	GPX4	88.5	0	30	0	0.69802006	FALSE	0	GPX4	20358	0.06818299
793035	taxon:9606	2.67260123	4.42E-05	180857	1902	glutamate ionotropic receptor NMDA type subunit 2D	gene	biological_process-&-1&-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0000165-&&-MAPK cascade-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0001964-&&-startle response-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0004972-&&-NMDA glutamate receptor activity-%%-GO:0004970-&&-ionotropic glutamate receptor activity-%%-GO:0005515-&&-protein binding	G:9606:GRIN2D			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04720-&&-Long-term potentiation-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05030-&&-Cocaine addiction-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05031-&&-Amphetamine addiction	GRIN2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIN2D	0.37416731	0.10804598	30	4	FALSE	GRIN2D	GRIN2D	127.9	0	30	0	0.72123313	FALSE	0	GRIN2D	61604	0.05995935
793100	taxon:9606	2.58405546	4.50E-05	180735	1902	glucosylceramidase beta	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006680-&&-glucosylceramide catabolic process-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1905165-&&-regulation of lysosomal protein catabolic process-%%-GO:0032268-&&-regulation of cellular protein metabolic process-%%-GO:0043627-&&-response to estrogen-%%-GO:0046512-&&-sphingosine biosynthetic process-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0009268-&&-response to pH-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:1905037-&&-autophagosome organization-%%-GO:0031175-&&-neuron projection development-%%-GO:0023021-&&-termination of signal transduction-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:1903061-&&-positive regulation of protein lipidation-%%-GO:1903052-&&-positive regulation of proteolysis involved in cellular protein catabolic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:1904925-&&-positive regulation of mitophagy in response to mitochondrial depolarization-%%-GO:0043243-&&-positive regulation of protein complex disassembly-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:1904457-&&-positive regulation of neuronal action potential-%%-GO:0033561-&&-regulation of water loss via skin-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0032463-&&-negative regulation of protein homooligomerization-%%-GO:0046513-&&-ceramide biosynthetic process-%%-GO:0036473-&&-cell death in response to oxidative stress-%%-GO:0033574-&&-response to testosterone-%%-GO:0097066-&&-response to thyroid hormone|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004348-&&-glucosylceramidase activity	G:9606:GBA			KEGG-&-1&-hsa00511-&&-Other glycan degradation-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism-%%-hsa04142-&&-Lysosome	GBA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBA	0.3869886	0.12873563	30	4	FALSE	GBA	GBA	165.1666667	0	30	0	0.73599076	FALSE	0	GBA	60026	0.06201929
793102	taxon:9606	2.76792185	3.52E-05	180730	1902	guanylate binding protein 2	gene	biological_process-&-1&-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:GBP2			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	GBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBP2	0.36128188	0.09885057	30	4	FALSE	GBP2	GBP2	83.06666667	0	30	0	0.70534636	FALSE	0	GBP2	42740	0.05354908
793268	taxon:9606	2.45549078	9.81E-05	180396	1902	glycogen synthase 1	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0005978-&&-glycogen biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016234-&&-inclusion body-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0061547-&&-glycogen synthase activity, transferring glucose-1-phosphate-%%-GO:0004373-&&-glycogen (starch) synthase activity-%%-GO:0005536-&&-glucose binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:GYS1	GYS1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04931-&&-Insulin resistance-%%-hsa00500-&&-Starch and sucrose metabolism	GYS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GYS1	0.40725056	0.08505747	30	4	FALSE	GYS1	GYS1	222.4666667	0	30	0	0.7574182	FALSE	0	GYS1	135094	0.06431327
787043	taxon:9606	2.74334331	4.30E-05	163791	1902	NOP9 nucleolar protein	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:NOP9				NOP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOP9	0.36451872	0.04187192	29	4	FALSE	NOP9	NOP9	99.34482759	0	29	0	0.70944278	FALSE	0	NOP9	52630	0.05811997
787162	taxon:9606	2.73373247	1.00E-04	179951	1902	LDL receptor related protein 6	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0090009-&&-primitive streak formation-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0090244-&&-Wnt signaling pathway involved in somitogenesis-%%-GO:0030917-&&-midbrain-hindbrain boundary development-%%-GO:0021794-&&-thalamus development-%%-GO:0060535-&&-trachea cartilage morphogenesis-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0090245-&&-axis elongation involved in somitogenesis-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0060325-&&-face morphogenesis-%%-GO:0021587-&&-cerebellum morphogenesis-%%-GO:0071397-&&-cellular response to cholesterol-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0044340-&&-canonical Wnt signaling pathway involved in regulation of cell proliferation-%%-GO:0060026-&&-convergent extension-%%-GO:0090118-&&-receptor-mediated endocytosis involved in cholesterol transport-%%-GO:2000055-&&-positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification-%%-GO:1901998-&&-toxin transport-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060021-&&-palate development-%%-GO:0003344-&&-pericardium morphogenesis-%%-GO:0014029-&&-neural crest formation-%%-GO:1904953-&&-Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0014033-&&-neural crest cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034392-&&-negative regulation of smooth muscle cell apoptotic process-%%-GO:0035261-&&-external genitalia morphogenesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0044335-&&-canonical Wnt signaling pathway involved in neural crest cell differentiation-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0044332-&&-Wnt signaling pathway involved in dorsal/ventral axis specification-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:1904886-&&-beta-catenin destruction complex disassembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:1990851-&&-Wnt-Frizzled-LRP5/6 complex-%%-GO:0045202-&&-synapse-%%-GO:0005769-&&-early endosome-%%-GO:0043025-&&-neuronal cell body-%%-GO:1990909-&&-Wnt signalosome-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0043235-&&-receptor complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005901-&&-caveola-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:1904928-&&-coreceptor activity involved in canonical Wnt signaling pathway-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0019210-&&-kinase inhibitor activity-%%-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0071936-&&-coreceptor activity involved in Wnt signaling pathway-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0019534-&&-toxin transporter activity-%%-GO:0005041-&&-low-density lipoprotein receptor activity	G:9606:LRP6			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	LRP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRP6	0.36580024	0.07977208	29	4	FALSE	LRP6	LRP6	97.37037037	0	28	0	0.71104459	FALSE	1	LRP6	86028	0.05559798
787177	taxon:9606	2.68599338	2.51E-05	179918	1902	NBR1, autophagy cargo receptor	gene	biological_process-&-1&-GO:0016236-&&-macroautophagy-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0051259-&&-protein oligomerization-%%-GO:0030500-&&-regulation of bone mineralization|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0031430-&&-M band-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005776-&&-autophagosome-%%-GO:0016020-&&-membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NBR1			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	NBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBR1	0.37230174	0.13105413	29	4	FALSE	NBR1	NBR1	124.037037	0	28	0	0.7190011	FALSE	1	NBR1	40324	0.06052879
787258	taxon:9606	2.65385221	5.84E-05	179788	1902	inositol 1,4,5-trisphosphate receptor type 3	gene	biological_process-&-1&-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0050917-&&-sensory perception of umami taste-%%-GO:0051592-&&-response to calcium ion-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0048016-&&-inositol phosphate-mediated signaling-%%-GO:0050916-&&-sensory perception of sweet taste-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007613-&&-memory-%%-GO:0050913-&&-sensory perception of bitter taste-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0060402-&&-calcium ion transport into cytosol-%%-GO:0030168-&&-platelet activation-%%-GO:0050796-&&-regulation of insulin secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045177-&&-apical part of cell-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0005903-&&-brush border-%%-GO:0043235-&&-receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005220-&&-inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity-%%-GO:0070679-&&-inositol 1,4,5 trisphosphate binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0000822-&&-inositol hexakisphosphate binding-%%-GO:0015278-&&-calcium-release channel activity-%%-GO:0043533-&&-inositol 1,3,4,5 tetrakisphosphate binding	G:9606:ITPR3			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04924-&&-Renin secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04540-&&-Gap junction-%%-hsa04911-&&-Insulin secretion-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ITPR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITPR3	0.37681073	0.16995074	29	4	FALSE	ITPR3	ITPR3	170.8275862	0	29	0	0.72435796	FALSE	0	ITPR3	75992	0.07664211
787470	taxon:9606	2.54025524	1.96E-05	179372	1902	class II major histocompatibility complex transactivator	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0006955-&&-immune response-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016310-&&-phosphorylation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0046677-&&-response to antibiotic-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0016746-&&-transferase activity, transferring acyl groups-%%-GO:0016301-&&-kinase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0033613-&&-activating transcription factor binding	G:9606:CIITA			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05164-&&-Influenza A	CIITA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIITA	0.39366123	0.19704433	29	4	FALSE	CIITA	CIITA	225.1034483	0	29	0	0.74329079	FALSE	0	CIITA	47774	0.07584348
787530	taxon:9606	2.75594769	2.06E-04	179243	1902	opioid receptor delta 1	gene	biological_process-&-1&-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0038003-&&-opioid receptor signaling pathway-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0032460-&&-negative regulation of protein oligomerization-%%-GO:0097237-&&-cellular response to toxic substance-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0042755-&&-eating behavior-%%-GO:0006955-&&-immune response-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043679-&&-axon terminus-%%-GO:0005737-&&-cytoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0032590-&&-dendrite membrane-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0038046-&&-enkephalin receptor activity-%%-GO:0042923-&&-neuropeptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004985-&&-opioid receptor activity	G:9606:OPRD1	OPRD1	TRUE	KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04022-&&-cGMP-PKG signaling pathway	OPRD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPRD1	0.36285159	0.13960114	29	4	FALSE	OPRD1	OPRD1	96.25925926	0	28	0	0.70734205	FALSE	1	OPRD1	297386	0.05956637
787565	taxon:9606	2.87726485	2.09E-05	179164	1902	NADH:ubiquinone oxidoreductase subunit B10	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity-%%-GO:0005515-&&-protein binding	G:9606:NDUFB10			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFB10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFB10	0.34755229	0.21921182	29	5	FALSE	NDUFB10	NDUFB10	63.44827586	0	29	0	0.68712253	FALSE	0	NDUFB10	24080	0.06489832
787569	taxon:9606	2.86954467	1.43E-05	179156	1902	NADH:ubiquinone oxidoreductase subunit S5	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005739-&&-mitochondrion-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFS5			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05016-&&-Huntington disease	NDUFS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFS5	0.34848734	0.43349754	29	4	FALSE	NDUFS5	NDUFS5	67.82758621	0	29	0	0.68840922	FALSE	0	NDUFS5	21452	0.06527805
787671	taxon:9606	2.61808729	3.25E-05	178986	1902	serpin family B member 9	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006915-&&-apoptotic process-%%-GO:0033668-&&-negative regulation by symbiont of host apoptotic process-%%-GO:0002448-&&-mast cell mediated immunity-%%-GO:0071391-&&-cellular response to estrogen stimulus-%%-GO:0006955-&&-immune response-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0042270-&&-protection from natural killer cell mediated cytotoxicity-%%-GO:0009617-&&-response to bacterium-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0005515-&&-protein binding	G:9606:SERPINB9			KEGG-&-1&-hsa05146-&&-Amoebiasis	SERPINB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB9	0.38195824	0.08374384	29	4	FALSE	SERPINB9	SERPINB9	175.0344828	0	29	0	0.73031879	FALSE	0	SERPINB9	71832	0.07099804
787741	taxon:9606	2.6103671	1.78E-05	178854	1902	RNA polymerase II subunit I	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010467-&&-gene expression-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006370-&&-7-methylguanosine mRNA capping|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:POLR2I			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa05016-&&-Huntington disease	POLR2I	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2I	0.38308788	0.42364532	29	4	FALSE	POLR2I	POLR2I	166.8965517	0	29	0	0.73160548	FALSE	0	POLR2I	39656	0.06605783
787761	taxon:9606	2.50291476	8.20E-05	178830	1902	pyrophosphatase (inorganic) 1	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0071344-&&-diphosphate metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004427-&&-inorganic diphosphatase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:PPA1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation	PPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPA1	0.39953418	0.11576355	29	4	FALSE	PPA1	PPA1	210.7586207	0	29	0	0.74951421	FALSE	0	PPA1	108660	0.0665671
787941	taxon:9606	2.65196156	3.29E-05	178538	1902	prolyl 4-hydroxylase subunit alpha 1	gene	biological_process-&-1&-GO:0030199-&&-collagen fibril organization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016222-&&-procollagen-proline 4-dioxygenase complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004656-&&-procollagen-proline 4-dioxygenase activity-%%-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0016702-&&-oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding	G:9606:P4HA1			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	P4HA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P4HA1	0.37707937	0.05665025	29	4	FALSE	P4HA1	P4HA1	141.0689655	0	29	0	0.72467307	FALSE	0	P4HA1	63284	0.06198994
788033	taxon:9606	2.78304711	1.64E-05	178328	1902	RAR related orphan receptor C	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0072539-&&-T-helper 17 cell differentiation-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0045598-&&-regulation of fat cell differentiation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0036315-&&-cellular response to sterol-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0019218-&&-regulation of steroid metabolic process-%%-GO:0030522-&&-intracellular receptor signaling pathway|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0098531-&&-transcription factor activity, direct ligand regulated sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008142-&&-oxysterol binding	G:9606:RORC			KEGG-&-1&-hsa04710-&&-Circadian rhythm-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04659-&&-Th17 cell differentiation	RORC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RORC	0.35931839	0.23399015	29	4	FALSE	RORC	RORC	100.0344828	0	29	0	0.70282548	FALSE	0	RORC	29480	0.06527415
788106	taxon:9606	2.64109028	4.42E-05	178231	1902	phosphorylase kinase catalytic subunit gamma 2	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045819-&&-positive regulation of glycogen catabolic process-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005964-&&-phosphorylase kinase complex|molecular_function-&-1&-GO:0050321-&&-tau-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004689-&&-phosphorylase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PHKG2			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04020-&&-Calcium signaling pathway	PHKG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHKG2	0.37863151	0.0862069	29	4	FALSE	PHKG2	PHKG2	126.0344828	0	29	0	0.72648495	FALSE	0	PHKG2	55294	0.05442603
788127	taxon:9606	2.62454703	7.51E-05	178202	1902	protein tyrosine phosphatase, receptor type G	gene	biological_process-&-1&-GO:1903385-&&-regulation of homophilic cell adhesion-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007420-&&-brain development-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0010633-&&-negative regulation of epithelial cell migration|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:PTPRG				PTPRG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRG	0.38101813	0.14529915	29	4	FALSE	PTPRG	PTPRG	144.7777778	0	28	0	0.72924216	FALSE	1	PTPRG	96108	0.05973962
788129	taxon:9606	2.56625177	1.14E-04	178193	1902	protein tyrosine phosphatase, receptor type S	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0034164-&&-negative regulation of toll-like receptor 9 signaling pathway-%%-GO:0048671-&&-negative regulation of collateral sprouting-%%-GO:0021766-&&-hippocampus development-%%-GO:0048681-&&-negative regulation of axon regeneration-%%-GO:0021549-&&-cerebellum development-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0021510-&&-spinal cord development-%%-GO:0061000-&&-negative regulation of dendritic spine development-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0032687-&&-negative regulation of interferon-alpha production-%%-GO:0022038-&&-corpus callosum development-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0099061-&&-integral component of postsynaptic density membrane-%%-GO:0030285-&&-integral component of synaptic vesicle membrane|molecular_function-&-1&-GO:0043395-&&-heparan sulfate proteoglycan binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035374-&&-chondroitin sulfate binding-%%-GO:0008201-&&-heparin binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:PTPRS				PTPRS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRS	0.38967338	0.05413105	29	4	FALSE	PTPRS	PTPRS	171.2592593	0	28	0	0.73895804	FALSE	1	PTPRS	145042	0.06171502
788181	taxon:9606	2.75831101	1.42E-04	178116	1902	RAP2A, member of RAS oncogene family	gene	biological_process-&-1&-GO:0034613-&&-cellular protein localization-%%-GO:0035690-&&-cellular response to drug-%%-GO:0030033-&&-microvillus assembly-%%-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045198-&&-establishment of epithelial cell apical/basal polarity-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:RAP2A				RAP2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP2A	0.3625407	0.05413105	29	5	FALSE	RAP2A	RAP2A	85.62962963	0	28	0	0.70694816	FALSE	1	RAP2A	187142	0.05400844
788200	taxon:9606	2.48952261	4.95E-06	178092	1902	RNA binding motif (RNP1, RRM) protein 3	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0006417-&&-regulation of translation-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0015934-&&-large ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM3				RBM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM3	0.40168344	0.45812808	29	4	FALSE	RBM3	RBM3	359.6896552	0	29	0	0.75174623	FALSE	0	RBM3	25530	0.11050373
788228	taxon:9606	2.67622499	5.36E-05	161666	1902	zinc finger and SCAN domain containing 1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZSCAN1				ZSCAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZSCAN1	0.37366066	0.03703704	29	5	FALSE	ZSCAN1	ZSCAN1	120.1111111	0	28	0	0.72062917	FALSE	1	ZSCAN1	61420	0.05654309
788336	taxon:9606	2.76429809	6.96E-05	177856	1902	sodium voltage-gated channel alpha subunit 5	gene	biological_process-&-1&-GO:0086046-&&-membrane depolarization during SA node cell action potential-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0086016-&&-AV node cell action potential-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0086043-&&-bundle of His cell action potential-%%-GO:0086045-&&-membrane depolarization during AV node cell action potential-%%-GO:0098912-&&-membrane depolarization during atrial cardiac muscle cell action potential-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0061337-&&-cardiac conduction-%%-GO:0086015-&&-SA node cell action potential-%%-GO:1902305-&&-regulation of sodium ion transmembrane transport-%%-GO:0003231-&&-cardiac ventricle development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0060372-&&-regulation of atrial cardiac muscle cell membrane repolarization-%%-GO:0021537-&&-telencephalon development-%%-GO:0060078-&&-regulation of postsynaptic membrane potential-%%-GO:0045760-&&-positive regulation of action potential-%%-GO:0086067-&&-AV node cell to bundle of His cell communication-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0021549-&&-cerebellum development-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0003360-&&-brainstem development-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0060373-&&-regulation of ventricular cardiac muscle cell membrane depolarization-%%-GO:0086047-&&-membrane depolarization during Purkinje myocyte cell action potential-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:0060371-&&-regulation of atrial cardiac muscle cell membrane depolarization-%%-GO:0051899-&&-membrane depolarization-%%-GO:0019228-&&-neuronal action potential-%%-GO:0086048-&&-membrane depolarization during bundle of His cell action potential-%%-GO:0086012-&&-membrane depolarization during cardiac muscle cell action potential-%%-GO:0086014-&&-atrial cardiac muscle cell action potential-%%-GO:0006814-&&-sodium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030315-&&-T-tubule-%%-GO:0005622-&&-intracellular-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0001518-&&-voltage-gated sodium channel complex-%%-GO:0014704-&&-intercalated disc-%%-GO:0009986-&&-cell surface-%%-GO:0030018-&&-Z disc-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0086006-&&-voltage-gated sodium channel activity involved in cardiac muscle cell action potential-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0005248-&&-voltage-gated sodium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0086062-&&-voltage-gated sodium channel activity involved in Purkinje myocyte action potential-%%-GO:0086061-&&-voltage-gated sodium channel activity involved in bundle of His cell action potential-%%-GO:0019901-&&-protein kinase binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0086063-&&-voltage-gated sodium channel activity involved in SA node cell action potential-%%-GO:0030506-&&-ankyrin binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0086060-&&-voltage-gated sodium channel activity involved in AV node cell action potential-%%-GO:0005516-&&-calmodulin binding	G:9606:SCN5A	SCN5A	TRUE	KEGG-&-1&-hsa04261-&&-Adrenergic signaling in cardiomyocytes	SCN5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCN5A	0.36175549	0.03418803	29	4	FALSE	SCN5A	SCN5A	87.40740741	0	28	0	0.70595032	FALSE	1	SCN5A	73442	0.05467039
788388	taxon:9606	2.50464787	6.99E-05	177752	1902	signal transducer and activator of transcription 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:STAT2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	STAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT2	0.39925772	0.23076923	29	4	FALSE	STAT2	STAT2	215.3333333	0	28	0	0.74922536	FALSE	1	STAT2	97000	0.0680437
788487	taxon:9606	2.69780999	7.23E-05	177557	1902	synuclein gamma	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0009306-&&-protein secretion-%%-GO:0050808-&&-synapse organization-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0046928-&&-regulation of neurotransmitter secretion|cellular_component-&-1&-GO:0005819-&&-spindle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SNCG				SNCG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNCG	0.37067103	0.05418719	29	4	FALSE	SNCG	SNCG	115.3793103	0	29	0	0.71703167	FALSE	0	SNCG	77330	0.0584822
788490	taxon:9606	2.86938711	3.73E-05	161169	1902	ZFP41 zinc finger protein	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZFP41				ZFP41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFP41	0.34850648	0.01231527	29	5	FALSE	ZFP41	ZFP41	45.75862069	0	29	0	0.68843548	FALSE	0	ZFP41	32006	0.04762772
788562	taxon:9606	2.59665984	5.30E-05	177433	1902	synaptotagmin 1	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0061024-&&-membrane organization-%%-GO:0048278-&&-vesicle docking-%%-GO:0005513-&&-detection of calcium ion-%%-GO:0031340-&&-positive regulation of vesicle fusion-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0017158-&&-regulation of calcium ion-dependent exocytosis-%%-GO:0006906-&&-vesicle fusion-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0098746-&&-fast, calcium ion-dependent exocytosis of neurotransmitter-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0048791-&&-calcium ion-regulated exocytosis of neurotransmitter-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0007420-&&-brain development-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1903305-&&-regulation of regulated secretory pathway-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0048488-&&-synaptic vesicle endocytosis|cellular_component-&-1&-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031045-&&-dense core granule-%%-GO:0070083-&&-clathrin-sculpted monoamine transport vesicle membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0030285-&&-integral component of synaptic vesicle membrane-%%-GO:0042584-&&-chromaffin granule membrane-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0060201-&&-clathrin-sculpted acetylcholine transport vesicle membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0060203-&&-clathrin-sculpted glutamate transport vesicle membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043005-&&-neuron projection-%%-GO:0043195-&&-terminal bouton-%%-GO:0060076-&&-excitatory synapse-%%-GO:0031201-&&-SNARE complex-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0030348-&&-syntaxin-3 binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005545-&&-1-phosphatidylinositol binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030276-&&-clathrin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0005516-&&-calmodulin binding	G:9606:SYT1			KEGG-&-1&-hsa04721-&&-Synaptic vesicle cycle	SYT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYT1	0.38511013	0.09116809	29	4	FALSE	SYT1	SYT1	155.6296296	0	28	0	0.73389003	FALSE	1	SYT1	70124	0.05981481
788581	taxon:9606	2.71388057	3.90E-05	177403	1902	transporter 1, ATP binding cassette subfamily B member	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0002250-&&-adaptive immune response-%%-GO:0046967-&&-cytosol to ER transport-%%-GO:0015833-&&-peptide transport-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0006952-&&-defense response-%%-GO:1990668-&&-vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane-%%-GO:0019885-&&-antigen processing and presentation of endogenous peptide antigen via MHC class I-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0019060-&&-intracellular transport of viral protein in host cell|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0042825-&&-TAP complex-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043657-&&-host cell-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0046978-&&-TAP1 binding-%%-GO:0005524-&&-ATP binding-%%-GO:0015197-&&-peptide transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0023029-&&-MHC class Ib protein binding-%%-GO:0046979-&&-TAP2 binding-%%-GO:0042605-&&-peptide antigen binding-%%-GO:0042288-&&-MHC class I protein binding-%%-GO:0043531-&&-ADP binding-%%-GO:0015440-&&-peptide-transporting ATPase activity	G:9606:TAP1			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa02010-&&-ABC transporters-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa05163-&&-Human cytomegalovirus infection	TAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAP1	0.36847605	0.06896552	29	4	FALSE	TAP1	TAP1	102.2068966	0	29	0	0.71435324	FALSE	0	TAP1	50910	0.0541297
788863	taxon:9606	2.81865448	2.99E-04	176736	1902	vascular endothelial growth factor A	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:1901727-&&-positive regulation of histone deacetylase activity-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:1902336-&&-positive regulation of retinal ganglion cell axon guidance-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0048739-&&-cardiac muscle fiber development-%%-GO:0007399-&&-nervous system development-%%-GO:0001525-&&-angiogenesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0048469-&&-cell maturation-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0038190-&&-VEGF-activated neuropilin signaling pathway-%%-GO:0043129-&&-surfactant homeostasis-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002687-&&-positive regulation of leukocyte migration-%%-GO:0001822-&&-kidney development-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0090259-&&-regulation of retinal ganglion cell axon guidance-%%-GO:0001570-&&-vasculogenesis-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0003169-&&-coronary vein morphogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0038091-&&-positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0048842-&&-positive regulation of axon extension involved in axon guidance-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0007498-&&-mesoderm development-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030225-&&-macrophage differentiation-%%-GO:1903572-&&-positive regulation of protein kinase D signaling-%%-GO:0090037-&&-positive regulation of protein kinase C signaling-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0071679-&&-commissural neuron axon guidance-%%-GO:0001666-&&-response to hypoxia-%%-GO:0035148-&&-tube formation-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:1900086-&&-positive regulation of peptidyl-tyrosine autophosphorylation-%%-GO:0007595-&&-lactation-%%-GO:0036303-&&-lymph vessel morphogenesis-%%-GO:0060319-&&-primitive erythrocyte differentiation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0061419-&&-positive regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0060948-&&-cardiac vascular smooth muscle cell development-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0031077-&&-post-embryonic camera-type eye development-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0030823-&&-regulation of cGMP metabolic process-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030324-&&-lung development-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0040007-&&-growth-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis|cellular_component-&-1&-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0030141-&&-secretory granule|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding-%%-GO:0008201-&&-heparin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0048018-&&-receptor agonist activity-%%-GO:0043183-&&-vascular endothelial growth factor receptor 1 binding-%%-GO:0005172-&&-vascular endothelial growth factor receptor binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0050840-&&-extracellular matrix binding	G:9606:VEGFA	VEGFA	TRUE	KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	VEGFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VEGFA	0.35477921	0.05128205	29	4	FALSE	VEGFA	VEGFA	64	0	28	0	0.69689092	FALSE	1	VEGFA	426882	0.05281777
788873	taxon:9606	2.62754057	5.11E-05	176718	1902	vaccinia related kinase 2	gene	biological_process-&-1&-GO:0008360-&&-regulation of cell shape-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0016032-&&-viral process-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:2000659-&&-regulation of interleukin-1-mediated signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:VRK2				VRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VRK2	0.38058404	0.11083744	29	4	FALSE	VRK2	VRK2	141.7586207	0	29	0	0.72874324	FALSE	0	VRK2	76878	0.05888594
788885	taxon:9606	2.65968174	9.67E-05	176677	1902	X-box binding protein 1	gene	biological_process-&-1&-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0015031-&&-protein transport-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0035470-&&-positive regulation of vascular wound healing-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0031017-&&-exocrine pancreas development-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0055092-&&-sterol homeostasis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0002639-&&-positive regulation of immunoglobulin production-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0006955-&&-immune response-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0006914-&&-autophagy-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0035356-&&-cellular triglyceride homeostasis-%%-GO:0071332-&&-cellular response to fructose stimulus-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0031648-&&-protein destabilization-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:1990418-&&-response to insulin-like growth factor stimulus-%%-GO:0055089-&&-fatty acid homeostasis-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:1903489-&&-positive regulation of lactation-%%-GO:0060691-&&-epithelial cell maturation involved in salivary gland development-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0001889-&&-liver development-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051024-&&-positive regulation of immunoglobulin secretion-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:1900100-&&-positive regulation of plasma cell differentiation-%%-GO:0007517-&&-muscle organ development-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0031670-&&-cellular response to nutrient-%%-GO:0048666-&&-neuron development|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:XBP1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	XBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XBP1	0.37598484	0.07122507	29	4	FALSE	XBP1	XBP1	141.4814815	0	28	0	0.72338638	FALSE	1	XBP1	115278	0.06377858
788982	taxon:9606	2.51347093	2.53E-05	176469	1902	bromodomain containing 3	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0070577-&&-lysine-acetylated histone binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:BRD3				BRD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRD3	0.3978562	0.23891626	29	4	FALSE	BRD3	BRD3	316.137931	0	29	0	0.74775484	FALSE	0	BRD3	88000	0.10146676
789055	taxon:9606	2.72506696	2.91E-05	176272	1902	succinate-CoA ligase GDP-forming beta subunit	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0006104-&&-succinyl-CoA metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0045244-&&-succinate-CoA ligase complex (GDP-forming)-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004776-&&-succinate-CoA ligase (GDP-forming) activity-%%-GO:0019003-&&-GDP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding	G:9606:SUCLG2			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism	SUCLG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUCLG2	0.36696346	0.14285714	29	4	FALSE	SUCLG2	SUCLG2	108.6551724	0	29	0	0.71248884	FALSE	0	SUCLG2	36876	0.05895017
789093	taxon:9606	2.58736411	6.12E-05	176204	1902	sphingosine-1-phosphate lyase 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0008210-&&-estrogen metabolic process-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0006672-&&-ceramide metabolic process-%%-GO:0030149-&&-sphingolipid catabolic process-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0010761-&&-fibroblast migration-%%-GO:0030097-&&-hemopoiesis-%%-GO:0060325-&&-face morphogenesis-%%-GO:0001822-&&-kidney development-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0001553-&&-luteinization-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0060021-&&-palate development-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0097190-&&-apoptotic signaling pathway|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008117-&&-sphinganine-1-phosphate aldolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0016831-&&-carboxy-lyase activity	G:9606:SGPL1			KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	SGPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGPL1	0.38649373	0.13546798	29	4	FALSE	SGPL1	SGPL1	164.3448276	0	29	0	0.73543932	FALSE	0	SGPL1	92570	0.06150524
789215	taxon:9606	2.62249882	1.32E-04	175981	1902	mitogen-activated protein kinase-activated protein kinase 5	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007165-&&-signal transduction-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0090400-&&-stress-induced premature senescence-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MAPKAPK5			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAPKAPK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPKAPK5	0.38131571	0.14814815	29	4	FALSE	MAPKAPK5	MAPKAPK5	143.5555556	0	28	0	0.72958353	FALSE	1	MAPKAPK5	144062	0.05879136
789233	taxon:9606	2.66346305	1.12E-04	175941	1902	tumor necrosis factor superfamily member 11	gene	biological_process-&-1&-GO:1902533-&&-positive regulation of intracellular signal transduction-%%-GO:0071812-&&-positive regulation of fever generation by positive regulation of prostaglandin secretion-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0002158-&&-osteoclast proliferation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0033598-&&-mammary gland epithelial cell proliferation-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0051466-&&-positive regulation of corticotropin-releasing hormone secretion-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045453-&&-bone resorption-%%-GO:0071848-&&-positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling-%%-GO:0034112-&&-positive regulation of homotypic cell-cell adhesion-%%-GO:0038001-&&-paracrine signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0071847-&&-TNFSF11-mediated signaling pathway-%%-GO:2001206-&&-positive regulation of osteoclast development-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001503-&&-ossification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0032813-&&-tumor necrosis factor receptor superfamily binding	G:9606:TNFSF11	TNFSF11	TRUE	KEGG-&-1&-hsa04917-&&-Prolactin signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	TNFSF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFSF11	0.37545105	0.05698006	29	4	FALSE	TNFSF11	TNFSF11	131.1481482	0	28	0	0.72275616	FALSE	1	TNFSF11	118992	0.06044417
789330	taxon:9606	2.69387112	5.16E-05	175720	1902	ADAM metallopeptidase domain 15	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0070528-&&-protein kinase C signaling-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0006915-&&-apoptotic process-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0042246-&&-tissue regeneration-%%-GO:0045087-&&-innate immune response-%%-GO:0006508-&&-proteolysis-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:1900121-&&-negative regulation of receptor binding-%%-GO:0001525-&&-angiogenesis-%%-GO:0008584-&&-male gonad development-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005912-&&-adherens junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005178-&&-integrin binding	G:9606:ADAM15				ADAM15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAM15	0.37121301	0.08128079	29	4	FALSE	ADAM15	ADAM15	132.4137931	0	29	0	0.71768815	FALSE	0	ADAM15	72256	0.06707509
789355	taxon:9606	2.72995116	2.07E-05	142908	1902	PTGES3L-AARSD1 readthrough	gene		G:9606:PTGES3L-AARSD1				PTGES3L-AARSD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGES3L-AARSD1	0.36630692	0.16748768	29	4	FALSE	PTGES3L-AARSD1	PTGES3L-AARSD1	106.8275862	0	29	0	0.71167481	FALSE	0	PTGES3L-AARSD1	33086	0.06004422
789401	taxon:9606	2.49346148	2.06E-05	175553	1902	Kruppel like factor 4	gene	biological_process-&-1&-GO:0031077-&&-post-embryonic camera-type eye development-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0045415-&&-negative regulation of interleukin-8 biosynthetic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000342-&&-negative regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0007500-&&-mesodermal cell fate determination-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:1904798-&&-positive regulation of core promoter binding-%%-GO:0048679-&&-regulation of axon regeneration-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0046985-&&-positive regulation of hemoglobin biosynthetic process-%%-GO:1904998-&&-negative regulation of leukocyte adhesion to arterial endothelial cell-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0048730-&&-epidermis morphogenesis-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0071409-&&-cellular response to cycloheximide-%%-GO:0009913-&&-epidermal cell differentiation-%%-GO:0035166-&&-post-embryonic hemopoiesis-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0014740-&&-negative regulation of muscle hyperplasia-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0071363-&&-cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005719-&&-nuclear euchromatin-%%-GO:0044798-&&-nuclear transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0035014-&&-phosphatidylinositol 3-kinase regulator activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001010-&&-transcription factor activity, sequence-specific DNA binding transcription factor recruiting-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:KLF4			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	KLF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF4	0.40104891	0.24137931	29	4	FALSE	KLF4	KLF4	256.1034483	0	29	0	0.75108975	FALSE	0	KLF4	56208	0.07922926
789424	taxon:9606	2.89191744	3.82E-05	175513	1902	transmembrane 9 superfamily member 4	gene	biological_process-&-1&-GO:0006909-&&-phagocytosis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007155-&&-cell adhesion-%%-GO:0070072-&&-vacuolar proton-transporting V-type ATPase complex assembly-%%-GO:2000010-&&-positive regulation of protein localization to cell surface-%%-GO:0070863-&&-positive regulation of protein exit from endoplasmic reticulum-%%-GO:0051453-&&-regulation of intracellular pH|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TM9SF4				TM9SF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TM9SF4	0.34579134	0.01724138	29	5	FALSE	TM9SF4	TM9SF4	41.27586207	0	29	0	0.68468043	FALSE	0	TM9SF4	30154	0.04574402
789435	taxon:9606	2.65448243	3.25E-05	175483	1902	peptidylprolyl isomerase G	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0016018-&&-cyclosporin A binding-%%-GO:0005515-&&-protein binding	G:9606:PPIG	PPIG	TRUE		PPIG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIG	0.37672127	0.14285714	29	4	FALSE	PPIG	PPIG	137.4482759	0	29	0	0.72425293	FALSE	0	PPIG	51000	0.0612292
789459	taxon:9606	2.62659524	3.28E-05	175421	1902	ATP synthase, H+ transporting, mitochondrial Fo complex subunit F2	gene	biological_process-&-1&-GO:0015992-&&-proton transport-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0000276-&&-mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:ATP5J2			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa01100-&&-Metabolic pathways	ATP5J2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP5J2	0.38072101	0.05665025	29	4	FALSE	ATP5J2	ATP5J2	156.7241379	0	29	0	0.72890079	FALSE	0	ATP5J2	58574	0.06498288
789467	taxon:9606	2.74334331	2.48E-05	175402	1902	clock circadian regulator	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0016573-&&-histone acetylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042634-&&-regulation of hair cycle-%%-GO:0051775-&&-response to redox state-%%-GO:0007623-&&-circadian rhythm-%%-GO:0009648-&&-photoperiodism-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:2000074-&&-regulation of type B pancreatic cell development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0033391-&&-chromatoid body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0031490-&&-chromatin DNA binding	G:9606:CLOCK	CLOCK	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04710-&&-Circadian rhythm	CLOCK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLOCK	0.36451872	0.31034483	29	4	FALSE	CLOCK	CLOCK	124.1034483	0	29	0	0.70944278	FALSE	0	CLOCK	39418	0.07138606
789497	taxon:9606	2.78005357	2.85E-05	142565	1902	cerebellar degeneration-related protein 2	gene		G:9606:LOC101060399				LOC101060399	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC101060399	0.3597053	0.11965812	29	4	FALSE	LOC101060399	LOC101060399	82.03703704	0	28	0	0.70332441	FALSE	1	LOC101060399	37078	0.05361898
789651	taxon:9606	2.74586419	3.51E-05	174974	1902	nucleotide binding oligomerization domain containing 1	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0071225-&&-cellular response to muramyl dipeptide-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0009595-&&-detection of biotic stimulus-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0007254-&&-JNK cascade-%%-GO:0016045-&&-detection of bacterium-%%-GO:0006952-&&-defense response-%%-GO:0051259-&&-protein oligomerization-%%-GO:1904417-&&-positive regulation of xenophagy-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006954-&&-inflammatory response-%%-GO:0042228-&&-interleukin-8 biosynthetic process-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0002606-&&-positive regulation of dendritic cell antigen processing and presentation-%%-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0050700-&&-CARD domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042834-&&-peptidoglycan binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process	G:9606:NOD1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05133-&&-Pertussis-%%-hsa05131-&&-Shigellosis	NOD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOD1	0.36418407	0.13675214	29	4	FALSE	NOD1	NOD1	106.0740741	0	28	0	0.70902264	FALSE	1	NOD1	42708	0.06278096
789760	taxon:9606	2.73735623	4.54E-05	174755	1902	fem-1 homolog B	gene	biological_process-&-1&-GO:0051438-&&-regulation of ubiquitin-protein transferase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0060743-&&-epithelial cell maturation involved in prostate gland development-%%-GO:0060442-&&-branching involved in prostate gland morphogenesis-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005123-&&-death receptor binding-%%-GO:0005515-&&-protein binding	G:9606:FEM1B	FEM1B	TRUE		FEM1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FEM1B	0.36531599	0.21082621	29	4	FALSE	FEM1B	FEM1B	130.2222222	0	28	0	0.71044063	FALSE	1	FEM1B	55392	0.07611241
789935	taxon:9606	2.57885615	2.84E-05	174316	1902	stromal antigen 2	gene	biological_process-&-1&-GO:0032876-&&-negative regulation of DNA endoreduplication-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:STAG2			KEGG-&-1&-hsa04110-&&-Cell cycle	STAG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAG2	0.38776882	0.22906404	29	4	FALSE	STAG2	STAG2	209.6896552	0	29	0	0.73685731	FALSE	0	STAG2	55792	0.07720836
789940	taxon:9606	2.65920908	3.07E-05	174296	1902	TRAF3 interacting protein 2	gene	biological_process-&-1&-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0006959-&&-humoral immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0001783-&&-B cell apoptotic process-%%-GO:0048305-&&-immunoglobulin secretion|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TRAF3IP2			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa04218-&&-Cellular senescence	TRAF3IP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAF3IP2	0.37605166	0.23361823	29	4	FALSE	TRAF3IP2	TRAF3IP2	158.037037	0	28	0	0.72346515	FALSE	1	TRAF3IP2	44928	0.07207938
789974	taxon:9606	2.55443517	2.96E-05	174205	1902	cancer susceptibility 3	gene	biological_process-&-1&-GO:0008298-&&-intracellular mRNA localization-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006417-&&-regulation of translation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0008150-&&-biological_process-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005829-&&-cytosol-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:CASC3			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	CASC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASC3	0.39147598	0.18965517	29	4	FALSE	CASC3	CASC3	201.4137931	0	29	0	0.74092747	FALSE	0	CASC3	56874	0.07068481
790011	taxon:9606	2.56688199	2.35E-05	174119	1902	fibroblast growth factor receptor substrate 2	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0001759-&&-organ induction-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0046619-&&-optic placode formation involved in camera-type eye formation-%%-GO:0070307-&&-lens fiber cell development-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0008595-&&-anterior/posterior axis specification, embryo-%%-GO:0007411-&&-axon guidance-%%-GO:0003281-&&-ventricular septum development-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0007405-&&-neuroblast proliferation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0030900-&&-forebrain development-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2000726-&&-negative regulation of cardiac muscle cell differentiation-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005168-&&-neurotrophin TRKA receptor binding-%%-GO:0005104-&&-fibroblast growth factor receptor binding-%%-GO:0019211-&&-phosphatase activator activity	G:9606:FRS2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05205-&&-Proteoglycans in cancer	FRS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FRS2	0.38957771	0.25369458	29	4	FALSE	FRS2	FRS2	177.7586207	0	29	0	0.738853	FALSE	0	FRS2	45010	0.06411405
790079	taxon:9606	2.53458327	4.73E-05	173921	1902	A-kinase anchoring protein 13	gene	biological_process-&-1&-GO:0086023-&&-adrenergic receptor signaling pathway involved in heart process-%%-GO:0007507-&&-heart development-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010611-&&-regulation of cardiac muscle hypertrophy-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0071875-&&-adrenergic receptor signaling pathway-%%-GO:0071883-&&-activation of MAPK activity by adrenergic receptor signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060297-&&-regulation of sarcomere organization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051168-&&-nuclear export-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0060348-&&-bone development-%%-GO:1900169-&&-regulation of glucocorticoid mediated signaling pathway|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005884-&&-actin filament-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005938-&&-cell cortex|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0046872-&&-metal ion binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity-%%-GO:0051018-&&-protein kinase A binding	G:9606:AKAP13			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05163-&&-Human cytomegalovirus infection	AKAP13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP13	0.39454218	0.12807882	29	4	FALSE	AKAP13	AKAP13	195.5172414	0	29	0	0.74423612	FALSE	0	AKAP13	81252	0.06598524
790095	taxon:9606	2.54592721	3.41E-05	173887	1902	Gse1 coiled-coil protein	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GSE1				GSE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSE1	0.39278421	0.14245014	29	4	FALSE	GSE1	GSE1	193.4444444	0	28	0	0.74234547	FALSE	1	GSE1	65162	0.06635644
790159	taxon:9606	2.84685678	3.74E-05	173736	1902	mitogen-activated protein kinase binding protein 1	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAPKBP1				MAPKBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPKBP1	0.3512646	0.21182266	29	5	FALSE	MAPKBP1	MAPKBP1	80.4137931	0	29	0	0.69219054	FALSE	0	MAPKBP1	51450	0.06953277
790181	taxon:9606	2.76933985	2.95E-05	173701	1902	formin binding protein 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005764-&&-lysosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:FNBP1				FNBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FNBP1	0.36109689	0.09401709	29	4	FALSE	FNBP1	FNBP1	97.40740741	0	28	0	0.70511003	FALSE	1	FNBP1	39218	0.06441011
790182	taxon:9606	2.76870963	1.57E-05	173700	1902	SMG1, nonsense mediated mRNA decay associated PI3K related kinase	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0000723-&&-telomere maintenance-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006281-&&-DNA repair-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:SMG1			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	SMG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMG1	0.36117908	0.15099715	29	4	FALSE	SMG1	SMG1	107.7407407	0	28	0	0.70521506	FALSE	1	SMG1	23096	0.06896961
790242	taxon:9606	2.83314952	3.08E-05	173538	1902	SATB homeobox 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0001764-&&-neuron migration-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021902-&&-commitment of neuronal cell to specific neuron type in forebrain-%%-GO:0060021-&&-palate development-%%-GO:0002076-&&-osteoblast development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051216-&&-cartilage development-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0016569-&&-covalent chromatin modification|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:SATB2	SATB2	TRUE		SATB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SATB2	0.35296408	0.0591133	29	4	FALSE	SATB2	SATB2	81.44827586	0	29	0	0.69447508	FALSE	0	SATB2	48236	0.06376466
790372	taxon:9606	2.73420514	2.64E-05	173195	1902	cyclin dependent kinase 20	gene	biological_process-&-1&-GO:1904031-&&-positive regulation of cyclin-dependent protein kinase activity-%%-GO:0051301-&&-cell division-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007049-&&-cell cycle-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005929-&&-cilium-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019912-&&-cyclin-dependent protein kinase activating kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK20				CDK20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK20	0.36573701	0.06650246	29	4	FALSE	CDK20	CDK20	103.3448276	0	29	0	0.71096581	FALSE	0	CDK20	33216	0.05786517
790401	taxon:9606	2.60453758	5.77E-05	173119	1902	ADP ribosylation factor interacting protein 2	gene	biological_process-&-1&-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0034315-&&-regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0031529-&&-ruffle organization-%%-GO:0030032-&&-lamellipodium assembly|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:ARFIP2				ARFIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFIP2	0.38394531	0.07122507	29	4	FALSE	ARFIP2	ARFIP2	136.2592593	0	28	0	0.73257707	FALSE	1	ARFIP2	76548	0.05366353
790402	taxon:9606	2.55679849	2.92E-05	156724	1902	creatine kinase, mitochondrial 1A	gene	biological_process-&-1&-GO:0006600-&&-creatine metabolic process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004111-&&-creatine kinase activity	G:9606:CKMT1A			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	CKMT1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKMT1A	0.39111412	0.19373219	29	4	FALSE	CKMT1A	CKMT1A	245.037037	0	28	0	0.74053359	FALSE	1	CKMT1A	63440	0.08523027
790437	taxon:9606	2.67197101	2.95E-05	172991	1902	cytoskeleton associated protein 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007026-&&-negative regulation of microtubule depolymerization|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0015630-&&-microtubule cytoskeleton	G:9606:CKAP2				CKAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKAP2	0.37425556	0.11083744	29	4	FALSE	CKAP2	CKAP2	141.7586207	0	29	0	0.72133817	FALSE	0	CKAP2	55282	0.06590074
790606	taxon:9606	2.77847802	4.23E-05	171781	1902	PHD finger protein 21A	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016575-&&-histone deacetylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:1990391-&&-DNA repair complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042393-&&-histone binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:PHF21A				PHF21A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF21A	0.35990927	0.06896552	29	4	FALSE	PHF21A	PHF21A	102.2413793	0	29	0	0.703587	FALSE	0	PHF21A	50298	0.06675248
790648	taxon:9606	2.65873641	3.76E-05	171671	1902	inhibitor of growth family member 3	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0040008-&&-regulation of growth-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0032777-&&-Piccolo NuA4 histone acetyltransferase complex-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0035064-&&-methylated histone binding	G:9606:ING3				ING3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ING3	0.37611852	0.27832512	29	5	FALSE	ING3	ING3	128.6551724	0	29	0	0.72354393	FALSE	0	ING3	52822	0.05788566
790661	taxon:9606	2.52938396	5.49E-05	171556	1902	basic leucine zipper and W2 domains 2	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0045296-&&-cadherin binding	G:9606:BZW2				BZW2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BZW2	0.39535318	0.1453202	29	4	FALSE	BZW2	BZW2	192.7241379	0	29	0	0.74510267	FALSE	0	BZW2	84090	0.06410006
790663	taxon:9606	2.73262959	7.33E-05	171555	1902	chromosome 11 open reading frame 54	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0016788-&&-hydrolase activity, acting on ester bonds	G:9606:C11orf54				C11orf54	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C11orf54	0.36594788	0.12068966	29	4	FALSE	C11orf54	C11orf54	90.96551724	0	29	0	0.7112284	FALSE	0	C11orf54	63898	0.05111288
790690	taxon:9606	2.5306444	3.25E-05	171464	1902	ubiquitin specific peptidase 25	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:1904293-&&-negative regulation of ERAD pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0071108-&&-protein K48-linked deubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0032183-&&-SUMO binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0051117-&&-ATPase binding-%%-GO:1904455-&&-ubiquitin-specific protease activity involved in negative regulation of ERAD pathway-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:USP25			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	USP25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP25	0.39515627	0.14814815	29	4	FALSE	USP25	USP25	209.0740741	0	28	0	0.7448926	FALSE	1	USP25	51102	0.06993406
790850	taxon:9606	2.53505593	3.23E-05	170896	1902	mitochondrial ribosomal protein L39	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:MRPL39				MRPL39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL39	0.39446861	0.28817734	29	4	FALSE	MRPL39	MRPL39	232.2758621	0	29	0	0.74415734	FALSE	0	MRPL39	66362	0.07747694
790858	taxon:9606	2.78541043	5.48E-05	170872	1902	neuroligin 3	gene	biological_process-&-1&-GO:0060024-&&-rhythmic synaptic transmission-%%-GO:0007416-&&-synapse assembly-%%-GO:0060080-&&-inhibitory postsynaptic potential-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:2000969-&&-positive regulation of AMPA receptor activity-%%-GO:0007158-&&-neuron cell-cell adhesion-%%-GO:0097105-&&-presynaptic membrane assembly-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0071625-&&-vocalization behavior-%%-GO:2000331-&&-regulation of terminal button organization-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:1900271-&&-regulation of long-term synaptic potentiation-%%-GO:0008542-&&-visual learning-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0035176-&&-social behavior-%%-GO:0002087-&&-regulation of respiratory gaseous exchange by neurological system process-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0030534-&&-adult behavior-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0097104-&&-postsynaptic membrane assembly-%%-GO:0050808-&&-synapse organization-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:2000809-&&-positive regulation of synaptic vesicle clustering-%%-GO:0048675-&&-axon extension-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0007612-&&-learning-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0061002-&&-negative regulation of dendritic spine morphogenesis|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0060076-&&-excitatory synapse-%%-GO:0009986-&&-cell surface-%%-GO:0099055-&&-integral component of postsynaptic membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030054-&&-cell junction-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0042043-&&-neurexin family protein binding-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:NLGN3			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	NLGN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLGN3	0.35901352	0.02216749	29	4	FALSE	NLGN3	NLGN3	70.17241379	0	29	0	0.70243159	FALSE	0	NLGN3	52938	0.04934475
790860	taxon:9606	2.50149677	3.89E-05	170869	1902	DnaJ heat shock protein family (Hsp40) member C10	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0051787-&&-misfolded protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0016671-&&-oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	G:9606:DNAJC10			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC10	0.39976066	0.25369458	29	4	FALSE	DNAJC10	DNAJC10	314.4827586	0	29	0	0.74975054	FALSE	0	DNAJC10	83362	0.09897366
790895	taxon:9606	2.5971325	1.97E-05	170751	1902	CWC15 spliceosome associated protein homolog	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:CWC15			KEGG-&-1&-hsa03040-&&-Spliceosome	CWC15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CWC15	0.38504004	0.26108374	29	4	FALSE	CWC15	CWC15	270.7931035	0	29	0	0.73381125	FALSE	0	CWC15	50548	0.10472887
791022	taxon:9606	2.66109973	5.02E-05	170341	1902	F-box and leucine rich repeat protein 12	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXL12				FBXL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL12	0.37578449	0.09605911	29	5	FALSE	FBXL12	FBXL12	127.7241379	0	29	0	0.72315004	FALSE	0	FBXL12	67146	0.05821724
791137	taxon:9606	2.83346463	4.13E-05	169916	1902	basic leucine zipper ATF-like transcription factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0009615-&&-response to virus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:BATF3				BATF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BATF3	0.35292482	0.34188034	29	4	FALSE	BATF3	BATF3	74.85185185	0	28	0	0.69442256	FALSE	1	BATF3	48702	0.06340239
791150	taxon:9606	2.92043485	7.09E-05	169886	1902	solute carrier family 39 member 4	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0034224-&&-cellular response to zinc ion starvation-%%-GO:0071578-&&-zinc II ion transmembrane import-%%-GO:0006882-&&-cellular zinc ion homeostasis|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0055038-&&-recycling endosome membrane|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity	G:9606:SLC39A4			KEGG-&-1&-hsa04978-&&-Mineral absorption	SLC39A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A4	0.34241476	0.02463054	29	4	FALSE	SLC39A4	SLC39A4	33.13793103	0	29	0	0.67992752	FALSE	0	SLC39A4	67068	0.04872113
791151	taxon:9606	2.73688357	1.62E-05	169880	1902	chromodomain helicase DNA binding protein 7	gene	biological_process-&-1&-GO:0007512-&&-adult heart development-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0007628-&&-adult walking behavior-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0043584-&&-nose development-%%-GO:0021553-&&-olfactory nerve development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0060324-&&-face development-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0060021-&&-palate development-%%-GO:0003226-&&-right ventricular compact myocardium morphogenesis-%%-GO:0021772-&&-olfactory bulb development-%%-GO:0060173-&&-limb development-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0042048-&&-olfactory behavior-%%-GO:0001501-&&-skeletal system development-%%-GO:0060123-&&-regulation of growth hormone secretion-%%-GO:0007417-&&-central nervous system development-%%-GO:0030217-&&-T cell differentiation-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0008015-&&-blood circulation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0060429-&&-epithelium development-%%-GO:0030540-&&-female genitalia development-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0021545-&&-cranial nerve development-%%-GO:0048752-&&-semicircular canal morphogenesis-%%-GO:0050890-&&-cognition-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0060384-&&-innervation-%%-GO:0006364-&&-rRNA processing-%%-GO:0048806-&&-genitalia development-%%-GO:0001974-&&-blood vessel remodeling|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0005524-&&-ATP binding	G:9606:CHD7				CHD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD7	0.36537908	0.22660099	29	4	FALSE	CHD7	CHD7	137.9655172	0	29	0	0.71051941	FALSE	0	CHD7	27878	0.0766092
791164	taxon:9606	2.49503703	4.65E-05	169846	1902	SCY1 like pseudokinase 2	gene	biological_process-&-1&-GO:2000370-&&-positive regulation of clathrin-dependent endocytosis-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:2000286-&&-receptor internalization involved in canonical Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity	G:9606:SCYL2				SCYL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCYL2	0.40079566	0.14039409	29	4	FALSE	SCYL2	SCYL2	254.6206897	0	29	0	0.75082716	FALSE	0	SCYL2	83340	0.07882993
791190	taxon:9606	2.74728218	3.65E-05	169787	1902	septin 11	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0001725-&&-stress fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0030424-&&-axon|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:SEPT11			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT11	0.3639961	0.1182266	29	4	FALSE	SEPT11	SEPT11	89.96551724	0	29	0	0.7087863	FALSE	0	SEPT11	43722	0.05298471
791455	taxon:9606	2.57475973	6.60E-05	168572	1902	nucleic acid binding protein 2	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0051972-&&-regulation of telomerase activity-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0070200-&&-establishment of protein localization to telomere-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070876-&&-SOSS complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0061730-&&-C-rich strand telomeric DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0098505-&&-G-rich strand telomeric DNA binding-%%-GO:0005515-&&-protein binding	G:9606:NABP2				NABP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NABP2	0.38838575	0.10344828	29	4	FALSE	NABP2	NABP2	172.5862069	0	29	0	0.73754005	FALSE	0	NABP2	81516	0.06327751
791470	taxon:9606	2.46242319	2.28E-05	168501	1902	TNFAIP3 interacting protein 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0050821-&&-protein stabilization-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006954-&&-inflammatory response-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0034138-&&-toll-like receptor 3 signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0034134-&&-toll-like receptor 2 signaling pathway-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0050871-&&-positive regulation of B cell activation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0023035-&&-CD40 signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0046872-&&-metal ion binding	G:9606:TNIP2				TNIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNIP2	0.40610404	0.18965517	29	4	FALSE	TNIP2	TNIP2	237.7931035	0	29	0	0.7562628	FALSE	0	TNIP2	57228	0.06966265
791479	taxon:9606	2.66267528	5.03E-05	168463	1902	claspin	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0033314-&&-mitotic DNA replication checkpoint-%%-GO:0006260-&&-DNA replication-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006281-&&-DNA repair-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0010997-&&-anaphase-promoting complex binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:CLSPN				CLSPN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLSPN	0.37556213	0.11576355	29	4	FALSE	CLSPN	CLSPN	134.9655172	0	29	0	0.72288745	FALSE	0	CLSPN	57258	0.0611584
791486	taxon:9606	2.55963447	1.77E-05	168434	1902	methylcrotonoyl-CoA carboxylase 2	gene	biological_process-&-1&-GO:0006552-&&-leucine catabolic process-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0015936-&&-coenzyme A metabolic process|cellular_component-&-1&-GO:0002169-&&-3-methylcrotonyl-CoA carboxylase complex, mitochondrial-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:1905202-&&-methylcrotonoyl-CoA carboxylase complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004485-&&-methylcrotonoyl-CoA carboxylase activity-%%-GO:0005515-&&-protein binding	G:9606:MCCC2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	MCCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCCC2	0.39068078	0.14529915	29	4	FALSE	MCCC2	MCCC2	231.037037	0	28	0	0.74006092	FALSE	1	MCCC2	56202	0.08146842
791527	taxon:9606	2.70584528	5.66E-05	168245	1902	suppressor of variegation 3-9 homolog 2	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0036124-&&-histone H3-K9 trimethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0006333-&&-chromatin assembly or disassembly-%%-GO:0007049-&&-cell cycle-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0036123-&&-histone H3-K9 dimethylation-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:1904047-&&-S-adenosyl-L-methionine binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046974-&&-histone methyltransferase activity (H3-K9 specific)-%%-GO:0008270-&&-zinc ion binding	G:9606:SUV39H2			KEGG-&-1&-hsa00310-&&-Lysine degradation	SUV39H2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUV39H2	0.36957028	0.12315271	29	4	FALSE	SUV39H2	SUV39H2	124.6896552	0	29	0	0.71569245	FALSE	0	SUV39H2	67678	0.06510605
791564	taxon:9606	2.52418465	5.59E-05	168011	1902	F-box and leucine rich repeat protein 18	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXL18				FBXL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL18	0.39616753	0.09605911	29	4	FALSE	FBXL18	FBXL18	207.2068966	0	29	0	0.74596922	FALSE	0	FBXL18	119494	0.06813693
791581	taxon:9606	2.62312904	1.30E-04	167935	1902	F-box protein 11	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0035246-&&-peptidyl-arginine N-methylation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005694-&&-chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016274-&&-protein-arginine N-methyltransferase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO11				FBXO11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO11	0.3812241	0.11330049	29	4	FALSE	FBXO11	FBXO11	161.6896552	0	29	0	0.72947849	FALSE	0	FBXO11	166938	0.06699017
791596	taxon:9606	2.70048842	9.26E-06	167884	1902	microcephalin 1	gene	biological_process-&-1&-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0021987-&&-cerebral cortex development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MCPH1				MCPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCPH1	0.37030338	0.24786325	29	4	FALSE	MCPH1	MCPH1	146.1111111	0	28	0	0.71658526	FALSE	1	MCPH1	19416	0.07366317
791638	taxon:9606	2.74901528	7.72E-05	167704	1902	docking protein 3	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK3				DOK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK3	0.36376662	0.14245014	29	4	FALSE	DOK3	DOK3	110.2592593	0	28	0	0.70849745	FALSE	1	DOK3	71188	0.0667881
791683	taxon:9606	2.72569718	2.05E-05	167450	1902	testis specific 10	gene	biological_process-&-1&-GO:0030031-&&-cell projection assembly-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0043005-&&-neuron projection-%%-GO:0031514-&&-motile cilium|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TSGA10				TSGA10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSGA10	0.36687861	0.09401709	29	4	FALSE	TSGA10	TSGA10	114	0	28	0	0.7123838	FALSE	1	TSGA10	35752	0.06379754
791687	taxon:9606	2.72995116	2.07E-05	167430	1902	alanyl-tRNA synthetase domain containing 1	gene	biological_process-&-1&-GO:0006419-&&-alanyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004813-&&-alanine-tRNA ligase activity-%%-GO:0003674-&&-molecular_function-%%-GO:0002196-&&-Ser-tRNA(Ala) hydrolase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding	G:9606:AARSD1				AARSD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AARSD1	0.36630692	0.16748768	29	4	FALSE	AARSD1	AARSD1	106.8275862	0	29	0	0.71167481	FALSE	0	AARSD1	33086	0.06004422
791717	taxon:9606	2.5703482	4.68E-05	167218	1902	sideroflexin 3	gene	biological_process-&-1&-GO:0055072-&&-iron ion homeostasis-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015075-&&-ion transmembrane transporter activity	G:9606:SFXN3				SFXN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFXN3	0.38905235	0.091133	29	4	FALSE	SFXN3	SFXN3	169.6896552	0	29	0	0.7382753	FALSE	0	SFXN3	76470	0.0616624
791774	taxon:9606	2.71703167	8.49E-05	166940	1902	anthrax toxin receptor 1	gene	biological_process-&-1&-GO:0022414-&&-reproductive process-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:1901202-&&-negative regulation of extracellular matrix assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0001568-&&-blood vessel development-%%-GO:1905050-&&-positive regulation of metallopeptidase activity-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0031527-&&-filopodium membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005518-&&-collagen binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ANTXR1	ANTXR1	TRUE	KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	ANTXR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANTXR1	0.36804871	0.05172414	29	4	FALSE	ANTXR1	ANTXR1	107.5172414	0	29	0	0.71382806	FALSE	0	ANTXR1	88738	0.05805065
791897	taxon:9606	2.81030408	5.38E-05	166531	1902	immunoglobin superfamily member 21	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region	G:9606:IGSF21				IGSF21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGSF21	0.35583338	0.01424501	29	4	FALSE	IGSF21	IGSF21	70.59259259	0	28	0	0.69828265	FALSE	1	IGSF21	56398	0.05340356
791983	taxon:9606	2.64770758	3.33E-05	182772	1902	amyloid beta precursor like protein 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:APLP2				APLP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APLP2	0.37768521	0.0997151	29	5	FALSE	APLP2	APLP2	142.5555556	0	28	0	0.72538207	FALSE	1	APLP2	50228	0.06263545
792062	taxon:9606	2.82952576	4.03E-05	166290	1902	lactate dehydrogenase A like 6B	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004459-&&-L-lactate dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:LDHAL6B			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis	LDHAL6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHAL6B	0.35341611	0.12561576	29	4	FALSE	LDHAL6B	LDHAL6B	70.24137931	0	29	0	0.69507904	FALSE	0	LDHAL6B	39464	0.05891046
792100	taxon:9606	2.82133291	1.13E-04	182605	1902	collagen type II alpha 1 chain	gene	biological_process-&-1&-GO:0060351-&&-cartilage development involved in endochondral bone morphogenesis-%%-GO:0030903-&&-notochord development-%%-GO:0071599-&&-otic vesicle development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0060272-&&-embryonic skeletal joint morphogenesis-%%-GO:0007417-&&-central nervous system development-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006029-&&-proteoglycan metabolic process-%%-GO:0001958-&&-endochondral ossification-%%-GO:0051216-&&-cartilage development-%%-GO:0060174-&&-limb bud formation-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0050776-&&-regulation of immune response-%%-GO:0001501-&&-skeletal system development-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0060021-&&-palate development-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0007601-&&-visual perception-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0001502-&&-cartilage condensation|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005585-&&-collagen type II trimer-%%-GO:0005604-&&-basement membrane|molecular_function-&-1&-GO:0030020-&&-extracellular matrix structural constituent conferring tensile strength-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:COL2A1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection	COL2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL2A1	0.3544424	0.05982906	29	4	FALSE	COL2A1	COL2A1	55.40740741	0	28	0	0.69644451	FALSE	1	COL2A1	89646	0.04475183
792233	taxon:9606	2.6650386	1.06E-04	182375	1902	ATPase plasma membrane Ca2+ transporting 4	gene	biological_process-&-1&-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0021766-&&-hippocampus development-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0010751-&&-negative regulation of nitric oxide mediated signal transduction-%%-GO:1901660-&&-calcium ion export-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:1901205-&&-negative regulation of adrenergic receptor signaling pathway involved in heart process-%%-GO:0070885-&&-negative regulation of calcineurin-NFAT signaling cascade-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051599-&&-response to hydrostatic pressure-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:1903243-&&-negative regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0098736-&&-negative regulation of the force of heart contraction-%%-GO:1900082-&&-negative regulation of arginine catabolic process-%%-GO:1902305-&&-regulation of sodium ion transmembrane transport-%%-GO:1903249-&&-negative regulation of citrulline biosynthetic process-%%-GO:0097553-&&-calcium ion transmembrane import into cytosol-%%-GO:1902083-&&-negative regulation of peptidyl-cysteine S-nitrosylation-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:1902806-&&-regulation of cell cycle G1/S phase transition-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0003407-&&-neural retina development-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0098703-&&-calcium ion import across plasma membrane|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0097228-&&-sperm principal piece-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043234-&&-protein complex-%%-GO:0036126-&&-sperm flagellum-%%-GO:0016020-&&-membrane-%%-GO:0005901-&&-caveola-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030315-&&-T-tubule-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0036487-&&-nitric-oxide synthase inhibitor activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ATP2B4			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04970-&&-Salivary secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2B4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2B4	0.37522909	0.07881773	29	4	FALSE	ATP2B4	ATP2B4	116.7241379	0	29	0	0.72249357	FALSE	0	ATP2B4	105082	0.05379374
792298	taxon:9606	2.78005357	2.85E-05	182268	1902	cerebellar degeneration related protein 2	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:CDR2				CDR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDR2	0.3597053	0.11965812	29	4	FALSE	CDR2	CDR2	82.03703704	0	28	0	0.70332441	FALSE	1	CDR2	37078	0.05361898
792339	taxon:9606	2.63463053	4.89E-05	182205	1902	chromogranin B	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0030141-&&-secretory granule|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding	G:9606:CHGB				CHGB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHGB	0.37955986	0.05172414	29	4	FALSE	CHGB	CHGB	126.1724138	0	29	0	0.72756158	FALSE	0	CHGB	60978	0.05320531
792358	taxon:9606	2.55679849	2.92E-05	182166	1902	creatine kinase, mitochondrial 1B	gene	biological_process-&-1&-GO:0006600-&&-creatine metabolic process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004111-&&-creatine kinase activity	G:9606:CKMT1B			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	CKMT1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKMT1B	0.39111412	0.19373219	29	4	FALSE	CKMT1B	CKMT1B	245.037037	0	28	0	0.74053359	FALSE	1	CKMT1B	63440	0.08523027
792405	taxon:9606	2.53883725	1.79E-05	182072	1902	citrate synthase	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004108-&&-citrate (Si)-synthase activity	G:9606:CS			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	CS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CS	0.3938811	0.16995074	29	4	FALSE	CS	CS	235.5517241	0	29	0	0.74352713	FALSE	0	CS	40034	0.07959353
792450	taxon:9606	2.74192532	2.92E-05	165622	1902	tripartite motif containing 9	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:0035544-&&-negative regulation of SNARE complex assembly-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:TRIM9				TRIM9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM9	0.36470723	0.07692308	29	4	FALSE	TRIM9	TRIM9	100.7407407	0	28	0	0.70967911	FALSE	1	TRIM9	43420	0.05853059
792466	taxon:9606	2.61367575	2.04E-05	181973	1902	AXL receptor tyrosine kinase	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0001764-&&-neuron migration-%%-GO:0021885-&&-forebrain cell migration-%%-GO:0030168-&&-platelet activation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0001961-&&-positive regulation of cytokine-mediated signaling pathway-%%-GO:0032825-&&-positive regulation of natural killer cell differentiation-%%-GO:0060068-&&-vagina development-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0032940-&&-secretion by cell-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0048549-&&-positive regulation of pinocytosis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0048469-&&-cell maturation-%%-GO:0006954-&&-inflammatory response-%%-GO:0006909-&&-phagocytosis-%%-GO:0051250-&&-negative regulation of lymphocyte activation-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0042698-&&-ovulation cycle-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0007165-&&-signal transduction-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:2000669-&&-negative regulation of dendritic cell apoptotic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0044228-&&-host cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0032036-&&-myosin heavy chain binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001786-&&-phosphatidylserine binding	G:9606:AXL			KEGG-&-1&-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	AXL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AXL	0.38260293	0.28774929	29	4	FALSE	AXL	AXL	192.6296296	0	28	0	0.73105404	FALSE	1	AXL	36646	0.0776583
792516	taxon:9606	2.47786356	3.07E-05	181867	1902	caldesmon 1	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0006928-&&-movement of cell or subcellular component|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030478-&&-actin cap-%%-GO:0030016-&&-myofibril-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0017022-&&-myosin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005523-&&-tropomyosin binding	G:9606:CALD1			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction	CALD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALD1	0.40357347	0.18472906	29	4	FALSE	CALD1	CALD1	284.4137931	0	29	0	0.75368941	FALSE	0	CALD1	68244	0.08548116
792578	taxon:9606	2.54230345	5.39E-05	181787	1902	cyclin G1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCNG1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer	CCNG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNG1	0.39334408	0.12315271	29	4	FALSE	CCNG1	CCNG1	180	0	29	0	0.74294942	FALSE	0	CCNG1	76442	0.06157551
792586	taxon:9606	2.88183394	5.35E-05	181761	1902	CD14 molecule	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0071726-&&-cellular response to diacyl bacterial lipopeptide-%%-GO:0034128-&&-negative regulation of MyD88-independent toll-like receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0070266-&&-necroptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0071727-&&-cellular response to triacyl bacterial lipopeptide-%%-GO:0006909-&&-phagocytosis-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0009408-&&-response to heat-%%-GO:0038123-&&-toll-like receptor TLR1:TLR2 signaling pathway-%%-GO:0038124-&&-toll-like receptor TLR6:TLR2 signaling pathway-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0071223-&&-cellular response to lipoteichoic acid|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0046696-&&-lipopolysaccharide receptor complex-%%-GO:0031362-&&-anchored component of external side of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0016019-&&-peptidoglycan receptor activity-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0070891-&&-lipoteichoic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0001847-&&-opsonin receptor activity	G:9606:CD14	CD14	TRUE	KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa05134-&&-Legionellosis-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05146-&&-Amoebiasis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05133-&&-Pertussis-%%-hsa04064-&&-NF-kappa B signaling pathway	CD14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD14	0.34700126	0.00738916	29	4	FALSE	CD14	CD14	41.27586207	0	29	0	0.68636101	FALSE	0	CD14	40438	0.04493092
792589	taxon:9606	2.59114542	2.46E-05	181753	1902	desmoglein 2	gene	biological_process-&-1&-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0031424-&&-keratinization-%%-GO:0086073-&&-bundle of His cell-Purkinje myocyte adhesion involved in cell communication-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0070268-&&-cornification-%%-GO:0007155-&&-cell adhesion-%%-GO:0032570-&&-response to progesterone-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0002934-&&-desmosome organization-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0003165-&&-Purkinje myocyte development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0014704-&&-intercalated disc-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030057-&&-desmosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0001533-&&-cornified envelope|molecular_function-&-1&-GO:0086083-&&-cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication-%%-GO:0005509-&&-calcium ion binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:DSG2			KEGG-&-1&-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	DSG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSG2	0.38592971	0.21674877	29	4	FALSE	DSG2	DSG2	213.0344828	0	29	0	0.7348091	FALSE	0	DSG2	68164	0.08138247
792681	taxon:9606	2.64739247	2.14E-04	181568	1902	decorin	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0019800-&&-peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:1900747-&&-negative regulation of vascular endothelial growth factor signaling pathway-%%-GO:0001822-&&-kidney development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0007568-&&-aging-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0001890-&&-placenta development-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0030206-&&-chondroitin sulfate biosynthetic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0051901-&&-positive regulation of mitochondrial depolarization-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0042060-&&-wound healing-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0030208-&&-dermatan sulfate biosynthetic process|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005589-&&-collagen type VI trimer-%%-GO:0005737-&&-cytoplasm-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0050840-&&-extracellular matrix binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005518-&&-collagen binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005539-&&-glycosaminoglycan binding	G:9606:DCN	DCN	TRUE	KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa04350-&&-TGF-beta signaling pathway	DCN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCN	0.37773017	0.07142857	29	4	FALSE	DCN	DCN	110.7241379	0	29	0	0.72543459	FALSE	0	DCN	184036	0.04906867
792805	taxon:9606	2.88750591	7.78E-05	181341	1902	elastase, neutrophil expressed	gene	biological_process-&-1&-GO:0050778-&&-positive regulation of immune response-%%-GO:0070947-&&-neutrophil mediated killing of fungus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045415-&&-negative regulation of interleukin-8 biosynthetic process-%%-GO:0006508-&&-proteolysis-%%-GO:0009411-&&-response to UV-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:1903238-&&-positive regulation of leukocyte tethering or rolling-%%-GO:0006909-&&-phagocytosis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0002438-&&-acute inflammatory response to antigenic stimulus-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0045079-&&-negative regulation of chemokine biosynthetic process-%%-GO:0001878-&&-response to yeast-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0050922-&&-negative regulation of chemotaxis-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0030163-&&-protein catabolic process-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0030141-&&-secretory granule|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0002020-&&-protease binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019955-&&-cytokine binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0008201-&&-heparin binding	G:9606:ELANE			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05322-&&-Systemic lupus erythematosus	ELANE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELANE	0.34631964	0.02279202	29	5	FALSE	ELANE	ELANE	48	0	28	0	0.68541568	FALSE	1	ELANE	60776	0.05252376
792862	taxon:9606	2.55144163	5.95E-05	181252	1902	esterase D	gene	biological_process-&-1&-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0008150-&&-biological_process-%%-GO:0046294-&&-formaldehyde catabolic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0047374-&&-methylumbelliferyl-acetate deacetylase activity-%%-GO:0018738-&&-S-formylglutathione hydrolase activity-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0016788-&&-hydrolase activity, acting on ester bonds	G:9606:ESD			KEGG-&-1&-hsa01200-&&-Carbon metabolism	ESD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESD	0.39193528	0.16524217	29	4	FALSE	ESD	ESD	197	0	28	0	0.7414264	FALSE	1	ESD	84282	0.06856752
793155	taxon:9606	2.82353868	6.57E-05	180621	1902	G protein subunit alpha 11	gene	biological_process-&-1&-GO:0048066-&&-developmental pigmentation-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0007507-&&-heart development-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0009649-&&-entrainment of circadian clock-%%-GO:0007165-&&-signal transduction-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0045634-&&-regulation of melanocyte differentiation-%%-GO:0071467-&&-cellular response to pH-%%-GO:0001501-&&-skeletal system development-%%-GO:0001508-&&-action potential-%%-GO:0007603-&&-phototransduction, visible light|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031826-&&-type 2A serotonin receptor binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding	G:9606:GNA11			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04934-&&-Cushing syndrome-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNA11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNA11	0.3541655	0.04187192	29	4	FALSE	GNA11	GNA11	59.34482759	0	29	0	0.69607689	FALSE	0	GNA11	56968	0.04784448
793273	taxon:9606	2.68867181	5.17E-05	180391	1902	granzyme B	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0016485-&&-protein processing-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0019835-&&-cytolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0005515-&&-protein binding	G:9606:GZMB	GZMB	TRUE	KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05330-&&-Allograft rejection-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04210-&&-Apoptosis-%%-hsa05332-&&-Graft-versus-host disease	GZMB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GZMB	0.37193085	0.12820513	29	4	FALSE	GZMB	GZMB	130	0	28	0	0.7185547	FALSE	1	GZMB	58052	0.06516808
793322	taxon:9606	2.59634473	3.15E-05	180316	1902	huntingtin interacting protein 1	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000588-&&-positive regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0048268-&&-clathrin coat assembly-%%-GO:0099637-&&-neurotransmitter receptor transport-%%-GO:0050821-&&-protein stabilization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0030154-&&-cell differentiation-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006915-&&-apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030100-&&-regulation of endocytosis|cellular_component-&-1&-GO:0098888-&&-extrinsic component of presynaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0098890-&&-extrinsic component of postsynaptic membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0098794-&&-postsynapse-%%-GO:0098793-&&-presynapse-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0035254-&&-glutamate receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0032051-&&-clathrin light chain binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0035612-&&-AP-2 adaptor complex binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051015-&&-actin filament binding	G:9606:HIP1			KEGG-&-1&-hsa05016-&&-Huntington disease	HIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIP1	0.38515687	0.16524217	29	4	FALSE	HIP1	HIP1	170.3703704	0	28	0	0.73394255	FALSE	1	HIP1	49762	0.06523682
787102	taxon:9606	2.6633055	3.93E-05	180055	1902	interleukin 2 receptor subunit beta	gene	biological_process-&-1&-GO:0038110-&&-interleukin-2-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006461-&&-protein complex assembly-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0016032-&&-viral process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004911-&&-interleukin-2 receptor activity-%%-GO:0019976-&&-interleukin-2 binding-%%-GO:0005515-&&-protein binding	G:9606:IL2RB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa05162-&&-Measles-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL2RB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL2RB	0.37547326	0.30952381	28	4	FALSE	IL2RB	IL2RB	157.2142857	0	28	0	0.72278242	FALSE	0	IL2RB	51264	0.07224921
787103	taxon:9606	2.78320466	1.12E-04	180054	1902	interleukin 2 receptor subunit gamma	gene	biological_process-&-1&-GO:0038111-&&-interleukin-7-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0016032-&&-viral process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0038110-&&-interleukin-2-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004913-&&-interleukin-4 receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004917-&&-interleukin-7 receptor activity-%%-GO:0004911-&&-interleukin-2 receptor activity-%%-GO:0019976-&&-interleukin-2 binding-%%-GO:0005515-&&-protein binding	G:9606:IL2RG			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05162-&&-Measles-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL2RG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL2RG	0.35929805	0.12433862	28	5	FALSE	IL2RG	IL2RG	91.75	0	28	0	0.70279922	FALSE	0	IL2RG	155486	0.06253047
787431	taxon:9606	2.84890499	1.06E-04	179451	1902	low density lipoprotein receptor	gene	biological_process-&-1&-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0061024-&&-membrane organization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0070508-&&-cholesterol import-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0006897-&&-endocytosis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0030299-&&-intestinal cholesterol absorption-%%-GO:0042159-&&-lipoprotein catabolic process-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0010899-&&-regulation of phosphatidylcholine catabolic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0090118-&&-receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0015914-&&-phospholipid transport-%%-GO:0030301-&&-cholesterol transport-%%-GO:2000188-&&-regulation of cholesterol homeostasis|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0097443-&&-sorting endosome-%%-GO:0045177-&&-apical part of cell-%%-GO:0005769-&&-early endosome-%%-GO:1990666-&&-PCSK9-LDLR complex-%%-GO:0043235-&&-receptor complex-%%-GO:0005764-&&-lysosome-%%-GO:0010008-&&-endosome membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009986-&&-cell surface-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0034362-&&-low-density lipoprotein particle|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0030229-&&-very-low-density lipoprotein particle receptor activity-%%-GO:0032050-&&-clathrin heavy chain binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0001948-&&-glycoprotein binding	G:9606:LDLR	LDLR	TRUE	KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05160-&&-Hepatitis C-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion	LDLR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDLR	0.35101206	0.02461538	28	4	FALSE	LDLR	LDLR	54.38461538	0	27	0	0.69184917	FALSE	1	LDLR	126544	0.05065312
787516	taxon:9606	2.74428864	3.69E-05	179301	1902	MPV17, mitochondrial inner membrane protein	gene	biological_process-&-1&-GO:0032836-&&-glomerular basement membrane development-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0042592-&&-homeostatic process-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0048839-&&-inner ear development-%%-GO:0000002-&&-mitochondrial genome maintenance|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:MPV17	MPV17	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome	MPV17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPV17	0.36439316	0.1031746	28	4	FALSE	MPV17	MPV17	89.64285714	0	28	0	0.70928523	FALSE	0	MPV17	45336	0.05196501
787540	taxon:9606	2.50086655	4.75E-05	179222	1902	protein phosphatase 1 regulatory subunit 10	gene	biological_process-&-1&-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006606-&&-protein import into nucleus|cellular_component-&-1&-GO:0072357-&&-PTW/PP1 phosphatase complex-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity	G:9606:PPP1R10				PPP1R10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R10	0.3998614	0.22153846	28	4	FALSE	PPP1R10	PPP1R10	262.2692308	0	27	0	0.74985557	FALSE	1	PPP1R10	72054	0.08226932
787550	taxon:9606	2.60989444	5.01E-05	179204	1902	macrophage stimulating 1 receptor	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009615-&&-response to virus-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007165-&&-signal transduction-%%-GO:0038145-&&-macrophage colony-stimulating factor signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0007338-&&-single fertilization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0006952-&&-defense response-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0001725-&&-stress fiber-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005773-&&-vacuole|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005011-&&-macrophage colony-stimulating factor receptor activity	G:9606:MST1R				MST1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MST1R	0.38315726	0.31692308	28	4	FALSE	MST1R	MST1R	229.2307692	0	27	0	0.73168426	FALSE	1	MST1R	63070	0.09147858
787560	taxon:9606	2.68725382	4.41E-05	179177	1902	nebulin	gene	biological_process-&-1&-GO:0007525-&&-somatic muscle development-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0030832-&&-regulation of actin filament length-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc-%%-GO:0070062-&&-extracellular exosome-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:NEB				NEB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEB	0.37212711	0.08994709	28	4	FALSE	NEB	NEB	110.9642857	0	28	0	0.71879103	FALSE	0	NEB	53288	0.05466436
787596	taxon:9606	2.80415945	4.20E-05	179120	1902	nuclear factor, erythroid 2 like 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0006783-&&-heme biosynthetic process-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:NFE2L1				NFE2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFE2L1	0.3566131	0.18153846	28	4	FALSE	NFE2L1	NFE2L1	83.61538462	0	27	0	0.69930676	FALSE	1	NFE2L1	41130	0.06037988
787613	taxon:9606	2.6417205	2.68E-05	179103	1902	nuclear transcription factor Y subunit gamma	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006457-&&-protein folding-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016602-&&-CCAAT-binding factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFYC			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05152-&&-Tuberculosis	NFYC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFYC	0.37854118	0.18783069	28	4	FALSE	NFYC	NFYC	149.25	0	28	0	0.72637992	FALSE	0	NFYC	44484	0.06375153
787618	taxon:9606	2.70174886	5.55E-05	179076	1902	NME/NM23 nucleoside diphosphate kinase 4	gene	biological_process-&-1&-GO:0006183-&&-GTP biosynthetic process-%%-GO:0006241-&&-CTP biosynthetic process-%%-GO:0006228-&&-UTP biosynthetic process-%%-GO:0009116-&&-nucleoside metabolic process-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0004550-&&-nucleoside diphosphate kinase activity	G:9606:NME4			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NME4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NME4	0.37013063	0.08923077	28	4	FALSE	NME4	NME4	124.1153846	0	27	0	0.71637519	FALSE	1	NME4	61564	0.06283417
787622	taxon:9606	2.77753269	5.89E-05	179069	1902	nitric oxide synthase 1	gene	biological_process-&-1&-GO:0098735-&&-positive regulation of the force of heart contraction-%%-GO:0009408-&&-response to heat-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0042311-&&-vasodilation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0007520-&&-myoblast fusion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:1902307-&&-positive regulation of sodium ion transmembrane transport-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0042738-&&-exogenous drug catabolic process-%%-GO:1901205-&&-negative regulation of adrenergic receptor signaling pathway involved in heart process-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0033555-&&-multicellular organismal response to stress-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0018119-&&-peptidyl-cysteine S-nitrosylation-%%-GO:0098924-&&-retrograde trans-synaptic signaling by nitric oxide-%%-GO:1902514-&&-regulation of calcium ion transmembrane transport via high voltage-gated calcium channel-%%-GO:0051612-&&-negative regulation of serotonin uptake-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0010523-&&-negative regulation of calcium ion transport into cytosol-%%-GO:1901206-&&-positive regulation of adrenergic receptor signaling pathway involved in heart process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0043197-&&-dendritic spine-%%-GO:0045121-&&-membrane raft-%%-GO:0030315-&&-T-tubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0042383-&&-sarcolemma-%%-GO:0005901-&&-caveola-%%-GO:1990425-&&-ryanodine receptor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045202-&&-synapse-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0001917-&&-photoreceptor inner segment|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0034618-&&-arginine binding-%%-GO:0046870-&&-cadmium ion binding-%%-GO:0010181-&&-FMN binding-%%-GO:0050661-&&-NADP binding-%%-GO:0004517-&&-nitric-oxide synthase activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0003958-&&-NADPH-hemoprotein reductase activity-%%-GO:0020037-&&-heme binding-%%-GO:0005516-&&-calmodulin binding	G:9606:NOS1			KEGG-&-1&-hsa04730-&&-Long-term depression-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04970-&&-Salivary secretion	NOS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOS1	0.36003177	0.06613757	28	4	FALSE	NOS1	NOS1	77.07142857	0	28	0	0.70374455	FALSE	0	NOS1	55266	0.05191732
787649	taxon:9606	2.79234284	7.79E-05	179018	1902	5'-nucleotidase ecto	gene	biological_process-&-1&-GO:0006196-&&-AMP catabolic process-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0046135-&&-pyrimidine nucleoside catabolic process-%%-GO:0046086-&&-adenosine biosynthetic process-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0016311-&&-dephosphorylation-%%-GO:0019674-&&-NAD metabolic process-%%-GO:0006195-&&-purine nucleotide catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031225-&&-anchored component of membrane|molecular_function-&-1&-GO:0008253-&&-5'-nucleotidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0000166-&&-nucleotide binding	G:9606:NT5E			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	NT5E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NT5E	0.35812221	0.01058201	28	5	FALSE	NT5E	NT5E	67.28571429	0	28	0	0.70127619	FALSE	0	NT5E	96478	0.04814451
787675	taxon:9606	2.51063495	5.96E-05	178968	1902	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0016477-&&-cell migration-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0050900-&&-leukocyte migration-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:2000369-&&-regulation of clathrin-dependent endocytosis-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0007411-&&-axon guidance-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0040016-&&-embryonic cleavage-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0016310-&&-phosphorylation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0006914-&&-autophagy-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0070527-&&-platelet aggregation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0060055-&&-angiogenesis involved in wound healing|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0030496-&&-midbody-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity	G:9606:PIK3CB			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3CB	0.39830562	0.21693122	28	4	FALSE	PIK3CB	PIK3CB	213.8928571	0	28	0	0.74822751	FALSE	0	PIK3CB	81408	0.06863105
787695	taxon:9606	2.86182448	1.33E-04	178934	1902	plasminogen activator, urokinase	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006508-&&-proteolysis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0061041-&&-regulation of wound healing-%%-GO:0007165-&&-signal transduction-%%-GO:0014910-&&-regulation of smooth muscle cell migration-%%-GO:0042730-&&-fibrinolysis-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0007596-&&-blood coagulation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006935-&&-chemotaxis-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:2000097-&&-regulation of smooth muscle cell-matrix adhesion-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:PLAU	PLAU	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04610-&&-Complement and coagulation cascades	PLAU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLAU	0.34942744	0.05230769	28	4	FALSE	PLAU	PLAU	46.07692308	0	27	0	0.68969592	FALSE	1	PLAU	96556	0.04538156
787728	taxon:9606	2.55774382	1.68E-05	178866	1902	DNA polymerase epsilon, catalytic subunit	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0045004-&&-DNA replication proofreading-%%-GO:0006260-&&-DNA replication-%%-GO:0048568-&&-embryonic organ development-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006272-&&-leading strand elongation-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0006287-&&-base-excision repair, gap-filling-%%-GO:0000722-&&-telomere maintenance via recombination|cellular_component-&-1&-GO:0008622-&&-epsilon DNA polymerase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008310-&&-single-stranded DNA 3'-5' exodeoxyribonuclease activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding	G:9606:POLE			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	POLE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLE	0.39096957	0.17195767	28	4	FALSE	POLE	POLE	219.8214286	0	28	0	0.74037603	FALSE	0	POLE	46148	0.07749849
787923	taxon:9606	2.54986608	2.53E-05	178607	1902	protein tyrosine kinase 6	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity-%%-GO:0016477-&&-cell migration-%%-GO:0060575-&&-intestinal epithelial cell differentiation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0042506-&&-tyrosine phosphorylation of Stat5 protein-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0042503-&&-tyrosine phosphorylation of Stat3 protein-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PTK6				PTK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTK6	0.39217746	0.15076923	28	5	FALSE	PTK6	PTK6	199.7692308	0	27	0	0.74168899	FALSE	1	PTK6	52604	0.06920678
787930	taxon:9606	2.40570348	6.52E-05	178571	1902	OPA1, mitochondrial dynamin like GTPase	gene	biological_process-&-1&-GO:0003374-&&-dynamin family protein polymerization involved in mitochondrial fission-%%-GO:0006915-&&-apoptotic process-%%-GO:0007007-&&-inner mitochondrial membrane organization-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0000002-&&-mitochondrial genome maintenance-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0010636-&&-positive regulation of mitochondrial fusion-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0090398-&&-cellular senescence-%%-GO:0014042-&&-positive regulation of neuron maturation-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0007601-&&-visual perception-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0031314-&&-extrinsic component of mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030061-&&-mitochondrial crista|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005525-&&-GTP binding	G:9606:OPA1				OPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPA1	0.41567883	0.14550265	28	4	FALSE	OPA1	OPA1	311.0357143	0	28	0	0.76571609	FALSE	0	OPA1	115202	0.08218156
788004	taxon:9606	2.73231448	3.09E-05	178422	1902	platelet and endothelial cell adhesion molecule 1	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0050904-&&-diapedesis-%%-GO:0007165-&&-signal transduction-%%-GO:0006909-&&-phagocytosis-%%-GO:0008037-&&-cell recognition-%%-GO:0007155-&&-cell adhesion-%%-GO:0072011-&&-glomerular endothelium development-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PECAM1	PECAM1	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05144-&&-Malaria	PECAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PECAM1	0.36599008	0.17538462	28	5	FALSE	PECAM1	PECAM1	134.1538462	0	27	0	0.71128092	FALSE	1	PECAM1	37882	0.07759081
788081	taxon:9606	2.67732787	2.61E-05	161884	1902	tetratricopeptide repeat domain 9C	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TTC9C				TTC9C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC9C	0.37350674	0.14285714	28	4	FALSE	TTC9C	TTC9C	130.7142857	0	28	0	0.72044535	FALSE	0	TTC9C	47530	0.06202918
788155	taxon:9606	2.72238853	3.59E-05	178154	1902	RAB6A, member RAS oncogene family	gene	biological_process-&-1&-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0018125-&&-peptidyl-cysteine methylation-%%-GO:0061024-&&-membrane organization-%%-GO:0000042-&&-protein targeting to Golgi-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016032-&&-viral process-%%-GO:0072385-&&-minus-end-directed organelle transport along microtubule|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070381-&&-endosome to plasma membrane transport vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding	G:9606:RAB6A				RAB6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB6A	0.3673245	0.13492063	28	4	FALSE	RAB6A	RAB6A	122.0714286	0	28	0	0.71293524	FALSE	0	RAB6A	48540	0.06610242
788165	taxon:9606	2.65952418	3.29E-05	178142	1902	RAD9 checkpoint clamp component A	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0000076-&&-DNA replication checkpoint-%%-GO:0006281-&&-DNA repair-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000077-&&-DNA damage checkpoint|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0030896-&&-checkpoint clamp complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008853-&&-exodeoxyribonuclease III activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:RAD9A			KEGG-&-1&-hsa04218-&&-Cellular senescence	RAD9A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD9A	0.37600711	0.17195767	28	4	FALSE	RAD9A	RAD9A	156.8214286	0	28	0	0.72341264	FALSE	0	RAD9A	53658	0.07040221
788307	taxon:9606	2.79533638	1.92E-05	177918	1902	retinoid X receptor gamma	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004886-&&-9-cis retinoic acid receptor activity	G:9606:RXRG			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa05216-&&-Thyroid cancer-%%-hsa05226-&&-Gastric cancer-%%-hsa05222-&&-Small cell lung cancer	RXRG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RXRG	0.3577387	0.14021164	28	4	FALSE	RXRG	RXRG	87.53571429	0	28	0	0.70077727	FALSE	0	RXRG	28368	0.06013872
788378	taxon:9606	2.61131243	2.18E-05	177779	1902	sperm specific antigen 2	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005102-&&-receptor binding	G:9606:SSFA2				SSFA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSFA2	0.3829492	0.21428571	28	4	FALSE	SSFA2	SSFA2	200.0357143	0	28	0	0.73144793	FALSE	0	SSFA2	36992	0.07987558
788642	taxon:9606	2.68725382	3.20E-05	177266	1902	MAF bZIP transcription factor K	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0071535-&&-RING-like zinc finger domain binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0005515-&&-protein binding	G:9606:MAFK				MAFK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAFK	0.37212711	0.35076923	28	4	FALSE	MAFK	MAFK	164.5769231	0	27	0	0.71879103	FALSE	1	MAFK	48190	0.07960255
788660	taxon:9606	2.56310068	4.02E-05	177239	1902	TGFB induced factor homeobox 1	gene	biological_process-&-1&-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:TGIF1	TGIF1	TRUE	KEGG-&-1&-hsa04350-&&-TGF-beta signaling pathway	TGIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGIF1	0.39015245	0.18253968	28	4	FALSE	TGIF1	TGIF1	193.7142857	0	28	0	0.73948322	FALSE	0	TGIF1	69976	0.06948075
788833	taxon:9606	2.60564046	1.12E-04	176786	1902	UDP-glucose 6-dehydrogenase	gene	biological_process-&-1&-GO:0006011-&&-UDP-glucose metabolic process-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0006065-&&-UDP-glucuronate biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0003979-&&-UDP-glucose 6-dehydrogenase activity	G:9606:UGDH			KEGG-&-1&-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00053-&&-Ascorbate and aldarate metabolism	UGDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UGDH	0.3837828	0.12615385	28	4	FALSE	UGDH	UGDH	151.7692308	0	27	0	0.73239326	FALSE	1	UGDH	133058	0.05932561
788839	taxon:9606	2.65873641	1.59E-05	176773	1902	uracil DNA glycosylase	gene	biological_process-&-1&-GO:0045008-&&-depyrimidination-%%-GO:0006284-&&-base-excision repair-%%-GO:0097510-&&-base-excision repair, AP site formation via deaminated base removal-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016447-&&-somatic recombination of immunoglobulin gene segments-%%-GO:0016032-&&-viral process-%%-GO:0006281-&&-DNA repair-%%-GO:0045830-&&-positive regulation of isotype switching|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004844-&&-uracil DNA N-glycosylase activity-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:UNG			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa05340-&&-Primary immunodeficiency	UNG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNG	0.37611852	0.25925926	28	4	FALSE	UNG	UNG	281.2857143	0	28	0	0.72354393	FALSE	0	UNG	51490	0.12576668
788913	taxon:9606	2.62171104	1.13E-04	176613	1902	phosphatidylinositol-4-phosphate 5-kinase type 1 alpha	gene	biological_process-&-1&-GO:0097178-&&-ruffle assembly-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0008654-&&-phospholipid biosynthetic process-%%-GO:0010761-&&-fibroblast migration-%%-GO:0006650-&&-glycerophospholipid metabolic process-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0016477-&&-cell migration-%%-GO:0006909-&&-phagocytosis-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0052810-&&-1-phosphatidylinositol-5-kinase activity-%%-GO:0019900-&&-kinase binding-%%-GO:0052812-&&-phosphatidylinositol-3,4-bisphosphate 5-kinase activity-%%-GO:0016308-&&-1-phosphatidylinositol-4-phosphate 5-kinase activity-%%-GO:0052811-&&-1-phosphatidylinositol-3-phosphate 4-kinase activity-%%-GO:0000285-&&-1-phosphatidylinositol-3-phosphate 5-kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:PIP5K1A			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04144-&&-Endocytosis-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa00562-&&-Inositol phosphate metabolism	PIP5K1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIP5K1A	0.38143029	0.04497354	28	4	FALSE	PIP5K1A	PIP5K1A	125.6071429	0	28	0	0.72971483	FALSE	0	PIP5K1A	109044	0.05153019
789060	taxon:9606	2.60579801	5.55E-05	176270	1902	succinate-CoA ligase ADP-forming beta subunit	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0006104-&&-succinyl-CoA metabolic process-%%-GO:0006781-&&-succinyl-CoA pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004775-&&-succinate-CoA ligase (ADP-forming) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:SUCLA2			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism	SUCLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUCLA2	0.3837596	0.08994709	28	4	FALSE	SUCLA2	SUCLA2	149.0357143	0	28	0	0.732367	FALSE	0	SUCLA2	71068	0.05840715
789112	taxon:9606	2.69087758	1.59E-04	176172	1902	HECT and RLD domain containing E3 ubiquitin protein ligase 3	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HERC3			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HERC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC3	0.37162597	0.11111111	28	4	FALSE	HERC3	HERC3	125.4642857	0	28	0	0.71818707	FALSE	0	HERC3	167652	0.06236647
789138	taxon:9606	2.72916338	4.49E-05	176130	1902	nucleolar protein 3	gene	biological_process-&-1&-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0042345-&&-regulation of NF-kappaB import into nucleus-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0014808-&&-release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0014736-&&-negative regulation of muscle atrophy-%%-GO:0060547-&&-negative regulation of necrotic cell death-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051259-&&-protein oligomerization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008380-&&-RNA splicing-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0014876-&&-response to injury involved in regulation of muscle adaptation-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:1902109-&&-negative regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0002931-&&-response to ischemia-%%-GO:0010659-&&-cardiac muscle cell apoptotic process|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0089720-&&-caspase binding-%%-GO:0035877-&&-death effector domain binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0003723-&&-RNA binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0042802-&&-identical protein binding	G:9606:NOL3				NOL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOL3	0.36641265	0.08923077	28	4	FALSE	NOL3	NOL3	98.53846154	0	27	0	0.7118061	FALSE	1	NOL3	49398	0.0542064
789301	taxon:9606	2.79202773	5.61E-06	175794	1902	mediator complex subunit 27	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016592-&&-mediator complex-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:MED27			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED27	0.35816263	0.66666667	28	5	FALSE	MED27	MED27	97.71428571	0	28	0	0.70132871	FALSE	0	MED27	11366	0.06704089
789306	taxon:9606	2.65873641	6.64E-05	175783	1902	homer scaffolding protein 3	gene	biological_process-&-1&-GO:0007216-&&-G-protein coupled glutamate receptor signaling pathway-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0045178-&&-basal part of cell-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:HOMER3			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa04724-&&-Glutamatergic synapse	HOMER3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOMER3	0.37611852	0.03076923	28	5	FALSE	HOMER3	HOMER3	121.3076923	0	27	0	0.72354393	FALSE	1	HOMER3	66216	0.05500263
789319	taxon:9606	2.76918229	2.09E-05	175754	1902	proteasome inhibitor subunit 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0038061-&&-NIK/NF-kappaB signaling-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:1901799-&&-negative regulation of proteasomal protein catabolic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0055085-&&-transmembrane transport-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005839-&&-proteasome core complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0070628-&&-proteasome binding	G:9606:PSMF1			KEGG-&-1&-hsa03050-&&-Proteasome	PSMF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMF1	0.36111743	0.12307692	28	5	FALSE	PSMF1	PSMF1	98.57692308	0	27	0	0.70513628	FALSE	1	PSMF1	29452	0.06212644
789475	taxon:9606	2.69654955	2.13E-05	175380	1902	ring finger protein 14	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0050681-&&-androgen receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF14				RNF14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF14	0.37084429	0.08923077	28	4	FALSE	RNF14	RNF14	144.9615385	0	27	0	0.71724174	FALSE	1	RNF14	40038	0.07254675
789605	taxon:9606	2.48243265	4.22E-05	175082	1902	oxidative stress responsive 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0071476-&&-cellular hypotonic response-%%-GO:2000687-&&-negative regulation of rubidium ion transmembrane transporter activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:OXSR1				OXSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OXSR1	0.40283067	0.14153846	28	4	FALSE	OXSR1	OXSR1	237.0384615	0	27	0	0.75292789	FALSE	1	OXSR1	62772	0.07176303
789752	taxon:9606	2.69245313	3.75E-05	174765	1902	peptidylprolyl isomerase F	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:2001243-&&-negative regulation of intrinsic apoptotic signaling pathway-%%-GO:1902445-&&-regulation of mitochondrial membrane permeability involved in programmed necrotic cell death-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0010849-&&-regulation of proton-transporting ATPase activity, rotational mechanism-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:2000276-&&-negative regulation of oxidative phosphorylation uncoupler activity-%%-GO:0090324-&&-negative regulation of oxidative phosphorylation-%%-GO:0002931-&&-response to ischemia-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010939-&&-regulation of necrotic cell death-%%-GO:0032780-&&-negative regulation of ATPase activity-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0070266-&&-necroptotic process-%%-GO:0071243-&&-cellular response to arsenic-containing substance|cellular_component-&-1&-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016018-&&-cyclosporin A binding	G:9606:PPIF			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05016-&&-Huntington disease-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPIF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIF	0.37140851	0.1005291	28	4	FALSE	PPIF	PPIF	110.6785714	0	28	0	0.71792448	FALSE	0	PPIF	51194	0.05535267
789787	taxon:9606	2.83677328	3.98E-05	174676	1902	PATJ, crumbs cell polarity complex component	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0070830-&&-bicellular tight junction assembly|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PATJ			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	PATJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PATJ	0.35251319	0.08615385	28	5	FALSE	PATJ	PATJ	63.46153846	0	27	0	0.69387112	FALSE	1	PATJ	37306	0.05407725
789969	taxon:9606	2.48211754	5.36E-05	174216	1902	exocyst complex component 3	gene	biological_process-&-1&-GO:0006887-&&-exocytosis-%%-GO:0051601-&&-exocyst localization-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0000145-&&-exocyst|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0000149-&&-SNARE binding	G:9606:EXOC3				EXOC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC3	0.40288181	0.23280423	28	4	FALSE	EXOC3	EXOC3	218.5357143	0	28	0	0.75298041	FALSE	0	EXOC3	81818	0.06593241
789970	taxon:9606	2.66897747	5.09E-05	174213	1902	Opa interacting protein 5	gene	biological_process-&-1&-GO:0007154-&&-cell communication-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007059-&&-chromosome segregation|cellular_component-&-1&-GO:0000775-&&-chromosome, centromeric region-%%-GO:0015030-&&-Cajal body-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0010369-&&-chromocenter-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:OIP5				OIP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OIP5	0.37467532	0.04615385	28	4	FALSE	OIP5	OIP5	141.5384615	0	27	0	0.72183709	FALSE	1	OIP5	62690	0.06525837
790062	taxon:9606	2.71167481	5.45E-05	173975	1902	coronin 1A	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0001845-&&-phagolysosome assembly-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032796-&&-uropod organization-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0006816-&&-calcium ion transport-%%-GO:0006909-&&-phagocytosis-%%-GO:0061502-&&-early endosome to recycling endosome transport-%%-GO:0031339-&&-negative regulation of vesicle fusion-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0045087-&&-innate immune response-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007015-&&-actin filament organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0043320-&&-natural killer cell degranulation-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0051126-&&-negative regulation of actin nucleation|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005884-&&-actin filament-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0001891-&&-phagocytic cup-%%-GO:0030424-&&-axon-%%-GO:0001772-&&-immunological synapse-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005769-&&-early endosome|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003785-&&-actin monomer binding-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0003779-&&-actin binding-%%-GO:0032036-&&-myosin heavy chain binding	G:9606:CORO1A			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis	CORO1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CORO1A	0.36877578	0.05291005	28	4	FALSE	CORO1A	CORO1A	99.25	0	28	0	0.71472087	FALSE	0	CORO1A	54148	0.05344588
790106	taxon:9606	2.50921695	5.15E-05	173864	1902	nucleoporin 210	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0046983-&&-protein dimerization activity	G:9606:NUP210			KEGG-&-1&-hsa03013-&&-RNA transport	NUP210	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP210	0.3985307	0.16402116	28	4	FALSE	NUP210	NUP210	283.8571429	0	28	0	0.74846384	FALSE	0	NUP210	94892	0.09089349
790137	taxon:9606	2.62785568	8.00E-05	173789	1902	activating transcription factor 6	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006990-&&-positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0007165-&&-signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0036500-&&-ATF6-mediated unfolded protein response-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006950-&&-response to stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007601-&&-visual perception-%%-GO:0001654-&&-eye development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:ATF6			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	ATF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATF6	0.3805384	0.08	28	4	FALSE	ATF6	ATF6	133.3846154	0	27	0	0.72869072	FALSE	1	ATF6	74712	0.05573623
790186	taxon:9606	2.65400977	3.17E-05	173689	1902	senataxin	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006310-&&-DNA recombination-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0000165-&&-MAPK cascade-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0007623-&&-circadian rhythm-%%-GO:2000806-&&-positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006353-&&-DNA-templated transcription, termination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0006396-&&-RNA processing-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0060566-&&-positive regulation of DNA-templated transcription, termination|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0000228-&&-nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0030426-&&-growth cone-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001147-&&-transcription termination site sequence-specific DNA binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005524-&&-ATP binding	G:9606:SETX				SETX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETX	0.37678836	0.15692308	28	4	FALSE	SETX	SETX	154.9615385	0	27	0	0.72433171	FALSE	1	SETX	47396	0.06911058
790209	taxon:9606	2.52166378	5.04E-05	173632	1902	microtubule associated serine/threonine kinase 2	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045075-&&-regulation of interleukin-12 biosynthetic process-%%-GO:0048515-&&-spermatid differentiation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019902-&&-phosphatase binding	G:9606:MAST2				MAST2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAST2	0.39656357	0.11375661	28	4	FALSE	MAST2	MAST2	202.1785714	0	28	0	0.74638937	FALSE	0	MAST2	75464	0.06633993
790216	taxon:9606	2.61588152	1.92E-05	173608	1902	mitogen-activated protein kinase 8 interacting protein 3	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0046328-&&-regulation of JNK cascade|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0019894-&&-kinesin binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005515-&&-protein binding-%%-GO:0008432-&&-JUN kinase binding	G:9606:MAPK8IP3			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAPK8IP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK8IP3	0.38228031	0.17846154	28	4	FALSE	MAPK8IP3	MAPK8IP3	146.1153846	0	27	0	0.73068641	FALSE	1	MAPK8IP3	38184	0.05880713
790357	taxon:9606	2.5755475	2.15E-05	173227	1902	nucleoporin 188	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0090521-&&-glomerular visceral epithelial cell migration-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006405-&&-RNA export from nucleus-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0044611-&&-nuclear pore inner ring|molecular_function-&-1&-GO:0017056-&&-structural constituent of nuclear pore	G:9606:NUP188			KEGG-&-1&-hsa03013-&&-RNA transport	NUP188	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP188	0.38826696	0.16931217	28	4	FALSE	NUP188	NUP188	241.0714286	0	28	0	0.73740875	FALSE	0	NUP188	53800	0.08809089
790548	taxon:9606	2.77422404	2.03E-05	156071	1902	Ras association domain family member 10	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005815-&&-microtubule organizing center	G:9606:RASSF10				RASSF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF10	0.36046115	0.06349206	28	4	FALSE	RASSF10	RASSF10	88.64285714	0	28	0	0.70429599	FALSE	0	RASSF10	29712	0.05814446
790710	taxon:9606	2.57491728	4.65E-05	171409	1902	hook microtubule tethering protein 2	gene	biological_process-&-1&-GO:0006897-&&-endocytosis-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0007032-&&-endosome organization-%%-GO:0015031-&&-protein transport-%%-GO:0007040-&&-lysosome organization-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0008333-&&-endosome to lysosome transport|cellular_component-&-1&-GO:0070695-&&-FHF complex-%%-GO:0030897-&&-HOPS complex-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0051959-&&-dynein light intermediate chain binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:HOOK2				HOOK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOOK2	0.38836199	0.05230769	28	4	FALSE	HOOK2	HOOK2	162.7692308	0	27	0	0.73751379	FALSE	1	HOOK2	71090	0.059438
790734	taxon:9606	2.48495352	2.09E-05	171358	1902	mitochondrial ribosomal protein S2	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS2			KEGG-&-1&-hsa03010-&&-Ribosome	MRPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS2	0.40242201	0.43121693	28	4	FALSE	MRPS2	MRPS2	243.1785714	0	28	0	0.75250775	FALSE	0	MRPS2	48424	0.07402696
790843	taxon:9606	2.48841973	3.30E-05	170975	1902	pelota homolog (Drosophila)	gene	biological_process-&-1&-GO:0019827-&&-stem cell population maintenance-%%-GO:0007492-&&-endoderm development-%%-GO:0070481-&&-nuclear-transcribed mRNA catabolic process, non-stop decay-%%-GO:0051276-&&-chromosome organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0006412-&&-translation-%%-GO:0032790-&&-ribosome disassembly-%%-GO:0051301-&&-cell division-%%-GO:0070651-&&-nonfunctional rRNA decay-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0007049-&&-cell cycle-%%-GO:0070966-&&-nuclear-transcribed mRNA catabolic process, no-go decay-%%-GO:0071025-&&-RNA surveillance-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004519-&&-endonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043022-&&-ribosome binding	G:9606:PELO			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	PELO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PELO	0.40186147	0.16137566	28	4	FALSE	PELO	PELO	232.3214286	0	28	0	0.75193005	FALSE	0	PELO	59236	0.07072168
790856	taxon:9606	2.78824642	4.34E-05	170883	1902	G protein subunit gamma 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0030168-&&-platelet activation-%%-GO:0008283-&&-cell proliferation-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0071870-&&-cellular response to catecholamine stimulus-%%-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex|molecular_function-&-1&-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0004871-&&-signal transducer activity	G:9606:GNG2			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNG2	0.35864836	0.10582011	28	4	FALSE	GNG2	GNG2	83.53571429	0	28	0	0.70195893	FALSE	0	GNG2	49180	0.05886057
790880	taxon:9606	2.64140539	2.87E-05	170791	1902	zinc finger and BTB domain containing 7B	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043376-&&-regulation of CD8-positive, alpha-beta T cell differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007398-&&-ectoderm development-%%-GO:0043370-&&-regulation of CD4-positive, alpha-beta T cell differentiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:ZBTB7B				ZBTB7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB7B	0.37858634	0.14769231	28	4	FALSE	ZBTB7B	ZBTB7B	173.2692308	0	27	0	0.72643244	FALSE	1	ZBTB7B	42444	0.07404299
790897	taxon:9606	2.58500079	2.46E-05	170743	1902	NCK interacting protein with SH3 domain	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:NCKIPSD				NCKIPSD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCKIPSD	0.38684708	0.21693122	28	4	FALSE	NCKIPSD	NCKIPSD	183.8928571	0	28	0	0.7358332	FALSE	0	NCKIPSD	55294	0.06909325
790902	taxon:9606	2.77674492	2.29E-05	170735	1902	anaphase promoting complex subunit 11	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051301-&&-cell division-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0097602-&&-cullin family protein binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:ANAPC11			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC11	0.36013391	0.25230769	28	4	FALSE	ANAPC11	ANAPC11	102.6153846	0	27	0	0.70387585	FALSE	1	ANAPC11	29190	0.06779101
790995	taxon:9606	2.54450922	2.78E-05	170466	1902	transmembrane protein 33	gene	biological_process-&-1&-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:1903899-&&-positive regulation of PERK-mediated unfolded protein response-%%-GO:1903371-&&-regulation of endoplasmic reticulum tubular network organization-%%-GO:0051292-&&-nuclear pore complex assembly-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0008150-&&-biological_process-%%-GO:0034613-&&-cellular protein localization|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042470-&&-melanosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005643-&&-nuclear pore-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0017056-&&-structural constituent of nuclear pore-%%-GO:0005515-&&-protein binding	G:9606:TMEM33				TMEM33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM33	0.3930031	0.07407407	28	4	FALSE	TMEM33	TMEM33	235.2857143	0	28	0	0.7425818	FALSE	0	TMEM33	78986	0.08032967
791046	taxon:9606	2.50433276	3.19E-05	170263	1902	seryl-tRNA synthetase 2, mitochondrial	gene	biological_process-&-1&-GO:0006434-&&-seryl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0097056-&&-selenocysteinyl-tRNA(Sec) biosynthetic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004828-&&-serine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding	G:9606:SARS2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	SARS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SARS2	0.39930796	0.16666667	28	4	FALSE	SARS2	SARS2	234.5357143	0	28	0	0.74927787	FALSE	0	SARS2	62070	0.07378929
791073	taxon:9606	2.52560265	3.53E-05	170140	1902	regulation of nuclear pre-mRNA domain containing 1A	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0070940-&&-dephosphorylation of RNA polymerase II C-terminal domain|cellular_component-&-1&-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RPRD1A				RPRD1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPRD1A	0.3959451	0.16931217	28	4	FALSE	RPRD1A	RPRD1A	198	0	28	0	0.74573289	FALSE	0	RPRD1A	71964	0.06508876
791140	taxon:9606	2.74318576	3.69E-05	169902	1902	cell division cycle associated 7 like	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CDCA7L				CDCA7L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDCA7L	0.36453966	0.09230769	28	4	FALSE	CDCA7L	CDCA7L	106.4615385	0	27	0	0.70946904	FALSE	1	CDCA7L	45150	0.06059941
791309	taxon:9606	2.63289743	4.32E-05	169249	1902	SET and MYND domain containing 2	gene	biological_process-&-1&-GO:0010452-&&-histone H3-K36 methylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0018026-&&-peptidyl-lysine monomethylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043516-&&-regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0018027-&&-peptidyl-lysine dimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0005515-&&-protein binding-%%-GO:0046975-&&-histone methyltransferase activity (H3-K36 specific)-%%-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0016278-&&-lysine N-methyltransferase activity-%%-GO:0002039-&&-p53 binding	G:9606:SMYD2				SMYD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMYD2	0.37980971	0.06084656	28	4	FALSE	SMYD2	SMYD2	151.6785714	0	28	0	0.72785043	FALSE	0	SMYD2	54964	0.06300161
791472	taxon:9606	2.64046006	9.88E-06	168499	1902	actin filament associated protein 1	gene	biological_process-&-1&-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0009966-&&-regulation of signal transduction|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding	G:9606:AFAP1				AFAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AFAP1	0.37872188	0.31384615	28	4	FALSE	AFAP1	AFAP1	188.1153846	0	27	0	0.72658999	FALSE	1	AFAP1	28666	0.08106764
791548	taxon:9606	2.72475185	2.51E-05	168115	1902	baculoviral IAP repeat containing 7	gene	biological_process-&-1&-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070247-&&-regulation of natural killer cell apoptotic process-%%-GO:0009966-&&-regulation of signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0008270-&&-zinc ion binding	G:9606:BIRC7			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer	BIRC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC7	0.3670059	0.15692308	28	4	FALSE	BIRC7	BIRC7	128.3846154	0	27	0	0.71254136	FALSE	1	BIRC7	35500	0.07076753
791586	taxon:9606	2.77170317	3.00E-05	167923	1902	N(alpha)-acetyltransferase 50, NatE catalytic subunit	gene	biological_process-&-1&-GO:0071962-&&-mitotic sister chromatid cohesion, centromeric-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0006474-&&-N-terminal protein amino acid acetylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031415-&&-NatA complex|molecular_function-&-1&-GO:0004596-&&-peptide alpha-N-acetyltransferase activity-%%-GO:0010485-&&-H4 histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0052858-&&-peptidyl-lysine acetyltransferase activity	G:9606:NAA50				NAA50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAA50	0.36078899	0.08994709	28	4	FALSE	NAA50	NAA50	105.3214286	0	28	0	0.70471614	FALSE	0	NAA50	38488	0.06733059
791704	taxon:9606	2.62580747	6.02E-06	167306	1902	testis specific serine kinase 6	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035092-&&-sperm chromatin condensation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:TSSK6				TSSK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSSK6	0.38083523	0.33333333	28	4	FALSE	TSSK6	TSSK6	290.6071429	0	28	0	0.72903209	FALSE	0	TSSK6	33722	0.12017015
791718	taxon:9606	2.8092012	7.64E-05	167215	1902	SHANK associated RH domain interactor	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0030262-&&-apoptotic nuclear changes-%%-GO:0031424-&&-keratinization-%%-GO:0007420-&&-brain development-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0097039-&&-protein linear polyubiquitination-%%-GO:2000348-&&-regulation of CD40 signaling pathway-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0071797-&&-LUBAC complex-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding	G:9606:SHARPIN			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	SHARPIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHARPIN	0.35597308	0.16923077	28	4	FALSE	SHARPIN	SHARPIN	81.80769231	0	27	0	0.69846647	FALSE	1	SHARPIN	69146	0.06313161
791763	taxon:9606	2.57286907	3.40E-05	166970	1902	PML-RARA regulated adaptor molecule 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043313-&&-regulation of neutrophil degranulation-%%-GO:0007229-&&-integrin-mediated signaling pathway|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:PRAM1				PRAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRAM1	0.38867116	0.13756614	28	4	FALSE	PRAM1	PRAM1	173.6428571	0	28	0	0.73785515	FALSE	0	PRAM1	71338	0.06316583
791767	taxon:9606	2.6765401	3.50E-05	166960	1902	ubiquitin specific peptidase 42	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:USP42				USP42	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP42	0.37361667	0.07142857	28	4	FALSE	USP42	USP42	140.8571429	0	28	0	0.72057665	FALSE	0	USP42	59174	0.06688992
792231	taxon:9606	2.49598235	2.37E-05	182378	1902	ATPase plasma membrane Ca2+ transporting 1	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0007420-&&-brain development-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0071386-&&-cellular response to corticosterone stimulus-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1901660-&&-calcium ion export-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0007568-&&-aging-%%-GO:0071305-&&-cellular response to vitamin D-%%-GO:0003407-&&-neural retina development-%%-GO:0006810-&&-transport-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032809-&&-neuronal cell body membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0032591-&&-dendritic spine membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005516-&&-calmodulin binding	G:9606:ATP2B1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04978-&&-Mineral absorption-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04970-&&-Salivary secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2B1	0.40064386	0.12433862	28	4	FALSE	ATP2B1	ATP2B1	232.75	0	28	0	0.75066961	FALSE	0	ATP2B1	58772	0.07248554
792305	taxon:9606	2.8241689	3.75E-05	182255	1902	CCAAT/enhancer binding protein gamma	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043353-&&-enucleate erythrocyte differentiation-%%-GO:0001889-&&-liver development-%%-GO:0016071-&&-mRNA metabolic process-%%-GO:0045078-&&-positive regulation of interferon-gamma biosynthetic process-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006955-&&-immune response-%%-GO:0042267-&&-natural killer cell mediated cytotoxicity-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0044377-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending	G:9606:CEBPG			KEGG-&-1&-hsa05152-&&-Tuberculosis	CEBPG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEBPG	0.35408647	0.38769231	28	4	FALSE	CEBPG	CEBPG	81.57692308	0	27	0	0.69597185	FALSE	1	CEBPG	46256	0.06360254
792310	taxon:9606	2.500709	7.69E-05	165860	1902	H2A histone family member V	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:H2AFV			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	H2AFV	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H2AFV	0.39988659	0.1984127	28	4	FALSE	H2AFV	H2AFV	292.5	0	28	0	0.74988183	FALSE	0	H2AFV	97320	0.09183193
792313	taxon:9606	2.63006145	3.51E-05	182246	1902	centromere protein F	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0007517-&&-muscle organ development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0021591-&&-ventricular system development-%%-GO:0051382-&&-kinetochore assembly-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0016202-&&-regulation of striated muscle tissue development-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007094-&&-mitotic spindle assembly checkpoint-%%-GO:0007059-&&-chromosome segregation-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0030154-&&-cell differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0097539-&&-ciliary transition fiber-%%-GO:0000776-&&-kinetochore-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016363-&&-nuclear matrix-%%-GO:0045120-&&-pronucleus-%%-GO:0005813-&&-centrosome-%%-GO:0000940-&&-condensed chromosome outer kinetochore-%%-GO:0005930-&&-axoneme-%%-GO:0030496-&&-midbody-%%-GO:0000785-&&-chromatin-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0070840-&&-dynein complex binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:CENPF	CENPF	TRUE		CENPF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPF	0.38021925	0.05538462	28	4	FALSE	CENPF	CENPF	186.7692308	0	27	0	0.72832309	FALSE	1	CENPF	57266	0.07762762
792410	taxon:9606	2.73751379	1.38E-05	182064	1902	colony stimulating factor 2 receptor beta common subunit	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0036016-&&-cellular response to interleukin-3-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0038156-&&-interleukin-3-mediated signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0038043-&&-interleukin-5-mediated signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0030526-&&-granulocyte macrophage colony-stimulating factor receptor complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004912-&&-interleukin-3 receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004914-&&-interleukin-5 receptor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004872-&&-receptor activity	G:9606:CSF2RB			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CSF2RB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSF2RB	0.36529496	0.29230769	28	4	FALSE	CSF2RB	CSF2RB	130.1538462	0	27	0	0.71041437	FALSE	1	CSF2RB	24390	0.07631401
792452	taxon:9606	2.80699543	9.80E-05	181999	1902	cathepsin L	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006508-&&-proteolysis-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0071888-&&-macrophage apoptotic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0036021-&&-endolysosome lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0005764-&&-lysosome-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0042393-&&-histone binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0097655-&&-serpin family protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0043394-&&-proteoglycan binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005518-&&-collagen binding-%%-GO:0001968-&&-fibronectin binding	G:9606:CTSL			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04142-&&-Lysosome-%%-hsa05323-&&-Rheumatoid arthritis	CTSL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSL	0.35625281	0.02769231	28	4	FALSE	CTSL	CTSL	65.80769231	0	27	0	0.69883409	FALSE	1	CTSL	72154	0.04878891
792724	taxon:9606	2.88766346	2.97E-05	181492	1902	discs large MAGUK scaffold protein 2	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0043113-&&-receptor clustering-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0046710-&&-GDP metabolic process-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0097120-&&-receptor localization to synapse|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0044224-&&-juxtaparanode region of axon|molecular_function-&-1&-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0004385-&&-guanylate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019900-&&-kinase binding	G:9606:DLG2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	DLG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLG2	0.34630074	0.13846154	28	4	FALSE	DLG2	DLG2	50	0	27	0	0.68538942	FALSE	1	DLG2	32666	0.05643056
792872	taxon:9606	2.67701276	5.10E-05	181247	1902	estrogen related receptor gamma	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005496-&&-steroid binding-%%-GO:0050682-&&-AF-2 domain binding-%%-GO:0005515-&&-protein binding	G:9606:ESRRG				ESRRG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESRRG	0.3735507	0.07076923	28	4	FALSE	ESRRG	ESRRG	118.4230769	0	27	0	0.72049787	FALSE	1	ESRRG	57792	0.05652318
792957	taxon:9606	2.87348354	5.98E-05	181087	1902	fibroblast growth factor receptor 4	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0070857-&&-regulation of bile acid biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:1903412-&&-response to bile acid-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:2000188-&&-regulation of cholesterol homeostasis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0055062-&&-phosphate ion homeostasis-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0030133-&&-transport vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005007-&&-fibroblast growth factor-activated receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:FGFR4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	FGFR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGFR4	0.34800965	0.01230769	28	4	FALSE	FGFR4	FGFR4	52.5	0	27	0	0.68775274	FALSE	1	FGFR4	54180	0.05379012
793025	taxon:9606	2.76918229	5.71E-05	180873	1902	glutamate ionotropic receptor AMPA type subunit 1	gene	biological_process-&-1&-GO:0099566-&&-regulation of postsynaptic cytosolic calcium ion concentration-%%-GO:0007165-&&-signal transduction-%%-GO:0007616-&&-long-term memory-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0031623-&&-receptor internalization-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0060292-&&-long term synaptic depression-%%-GO:0007268-&&-chemical synaptic transmission|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0098839-&&-postsynaptic density membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0044309-&&-neuron spine-%%-GO:0043025-&&-neuronal cell body-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0044308-&&-axonal spine-%%-GO:0030425-&&-dendrite-%%-GO:0032591-&&-dendritic spine membrane-%%-GO:0009986-&&-cell surface-%%-GO:0055037-&&-recycling endosome-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0008066-&&-glutamate receptor activity-%%-GO:1904315-&&-transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0099583-&&-neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration-%%-GO:0005515-&&-protein binding-%%-GO:0004971-&&-AMPA glutamate receptor activity-%%-GO:0005231-&&-excitatory extracellular ligand-gated ion channel activity-%%-GO:0030165-&&-PDZ domain binding	G:9606:GRIA1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04730-&&-Long-term depression-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05031-&&-Amphetamine addiction	GRIA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIA1	0.36111743	0.08923077	28	4	FALSE	GRIA1	GRIA1	83.84615385	0	27	0	0.70513628	FALSE	1	GRIA1	55532	0.05502102
793034	taxon:9606	2.76634631	3.25E-05	180860	1902	glutamate ionotropic receptor NMDA type subunit 2A	gene	biological_process-&-1&-GO:0030431-&&-sleep-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0022008-&&-neurogenesis-%%-GO:0033058-&&-directional locomotion-%%-GO:0001964-&&-startle response-%%-GO:0001975-&&-response to amphetamine-%%-GO:0007613-&&-memory-%%-GO:0045471-&&-response to ethanol-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0008542-&&-visual learning-%%-GO:0042428-&&-serotonin metabolic process-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0008104-&&-protein localization-%%-GO:0006810-&&-transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007611-&&-learning or memory-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0009611-&&-response to wounding-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005886-&&-plasma membrane-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0099061-&&-integral component of postsynaptic density membrane-%%-GO:0009986-&&-cell surface-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004972-&&-NMDA glutamate receptor activity-%%-GO:0008270-&&-zinc ion binding	G:9606:GRIN2A			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa05030-&&-Cocaine addiction-%%-hsa05033-&&-Nicotine addiction-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRIN2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIN2A	0.36148764	0.16615385	28	4	FALSE	GRIN2A	GRIN2A	100.4230769	0	27	0	0.70560895	FALSE	1	GRIN2A	39482	0.06471464
793040	taxon:9606	2.80179612	2.81E-05	164465	1902	forkhead box R2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXR2				FOXR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXR2	0.35691391	0.24867725	28	4	FALSE	FOXR2	FOXR2	79.07142857	0	28	0	0.69970065	FALSE	0	FOXR2	33104	0.05743419
793272	taxon:9606	2.49172838	1.57E-05	180388	1902	H1 histone family member 0	gene	biological_process-&-1&-GO:0006309-&&-apoptotic DNA fragmentation-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000786-&&-nucleosome-%%-GO:0005719-&&-nuclear euchromatin-%%-GO:0016604-&&-nuclear body-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005515-&&-protein binding	G:9606:H1F0				H1F0	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-H1F0	0.40132785	0.16137566	28	4	FALSE	H1F0	H1F0	273.5	0	28	0	0.7513786	FALSE	0	H1F0	41512	0.08435049
787104	taxon:9606	2.58909721	3.46E-05	163667	1902	SH3 domain containing ring finger 2	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0010923-&&-negative regulation of phosphatase activity|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0016740-&&-transferase activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004864-&&-protein phosphatase inhibitor activity	G:9606:SH3RF2				SH3RF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3RF2	0.38623501	0.06552707	27	4	FALSE	SH3RF2	SH3RF2	157.3333333	0	27	0	0.73515046	FALSE	0	SH3RF2	60998	0.05963019
787243	taxon:9606	2.58121947	7.04E-05	179811	1902	interferon regulatory factor 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008283-&&-cell proliferation-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007596-&&-blood coagulation-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:IRF2				IRF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF2	0.38741378	0.13390313	27	4	FALSE	IRF2	IRF2	170.0740741	0	27	0	0.73646342	FALSE	0	IRF2	75946	0.06359503
787281	taxon:9606	2.55963447	3.31E-04	179751	1902	potassium voltage-gated channel subfamily H member 2	gene	biological_process-&-1&-GO:0035690-&&-cellular response to drug-%%-GO:1902303-&&-negative regulation of potassium ion export-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0000160-&&-phosphorelay signal transduction system-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0055075-&&-potassium ion homeostasis-%%-GO:0061337-&&-cardiac conduction-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0071435-&&-potassium ion export-%%-GO:0097623-&&-potassium ion export across plasma membrane-%%-GO:0003064-&&-regulation of heart rate by hormone-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0086011-&&-membrane repolarization during action potential-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0086008-&&-voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization-%%-GO:0042802-&&-identical protein binding-%%-GO:0000155-&&-phosphorelay sensor kinase activity-%%-GO:0055131-&&-C3HC4-type RING finger domain binding-%%-GO:0005242-&&-inward rectifier potassium channel activity	G:9606:KCNH2	KCNH2	TRUE		KCNH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNH2	0.39068078	0.13666667	27	4	FALSE	KCNH2	KCNH2	197.84	0	26	0	0.74006092	FALSE	1	KCNH2	380784	0.07032028
787502	taxon:9606	2.96470774	2.26E-04	179334	1902	matrix metallopeptidase 3	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:1903209-&&-positive regulation of oxidative stress-induced cell death-%%-GO:0010727-&&-negative regulation of hydrogen peroxide metabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0032461-&&-positive regulation of protein oligomerization|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity	G:9606:MMP3	MMP3	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	MMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP3	0.33730138	0.02	27	4	FALSE	MMP3	MMP3	27.88	0	26	0	0.67254871	FALSE	1	MMP3	220094	0.05044444
787684	taxon:9606	2.66488105	2.74E-05	178958	1902	peptidylprolyl cis/trans isomerase, NIMA-interacting 4	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PIN4				PIN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIN4	0.37525127	0.05698006	27	4	FALSE	PIN4	PIN4	124.4444444	0	27	0	0.72251983	FALSE	0	PIN4	40410	0.0568874
788027	taxon:9606	2.520876	5.21E-05	178367	1902	ribonuclease/angiogenin inhibitor 1	gene	biological_process-&-1&-GO:0045765-&&-regulation of angiogenesis-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032311-&&-angiogenin-PRI complex|molecular_function-&-1&-GO:0008428-&&-ribonuclease inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:RNH1				RNH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNH1	0.3966875	0.09	27	4	FALSE	RNH1	RNH1	252.84	0	26	0	0.74652067	FALSE	1	RNH1	73586	0.08282152
788108	taxon:9606	2.64077517	3.91E-05	178226	1902	parathymosin	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0002376-&&-immune system process|cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:PTMS				PTMS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTMS	0.37867669	0.15669516	27	4	FALSE	PTMS	PTMS	140.4074074	0	27	0	0.72653747	FALSE	0	PTMS	61128	0.06050289
788320	taxon:9606	2.70710572	2.82E-05	177895	1902	S100 calcium binding protein B	gene	biological_process-&-1&-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007611-&&-learning or memory-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0007417-&&-central nervous system development-%%-GO:0007613-&&-memory-%%-GO:0008283-&&-cell proliferation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0007409-&&-axonogenesis-%%-GO:0051597-&&-response to methylmercury-%%-GO:2001015-&&-negative regulation of skeletal muscle cell differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0001726-&&-ruffle-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0044548-&&-S100 protein binding-%%-GO:0048156-&&-tau protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:S100B	S100B	TRUE		S100B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100B	0.36939821	0.09	27	4	FALSE	S100B	S100B	115.36	0	26	0	0.71548238	FALSE	1	S100B	34594	0.05980239
788482	taxon:9606	2.70222152	2.72E-05	161180	1902	family with sequence similarity 83 member H	gene	biological_process-&-1&-GO:0031214-&&-biomineral tissue development-%%-GO:0044380-&&-protein localization to cytoskeleton-%%-GO:0045104-&&-intermediate filament cytoskeleton organization-%%-GO:0030335-&&-positive regulation of cell migration|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:1990254-&&-keratin filament binding	G:9606:FAM83H				FAM83H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM83H	0.37006589	0.09401709	27	4	FALSE	FAM83H	FAM83H	118.962963	0	27	0	0.71629641	FALSE	0	FAM83H	40020	0.06101114
788622	taxon:9606	2.65873641	3.83E-05	177294	1902	TEK receptor tyrosine kinase	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0043627-&&-response to estrogen-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0060347-&&-heart trabecula formation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:2000351-&&-regulation of endothelial cell apoptotic process-%%-GO:0032878-&&-regulation of establishment or maintenance of cell polarity-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0007507-&&-heart development-%%-GO:0007165-&&-signal transduction-%%-GO:0000165-&&-MAPK cascade-%%-GO:1902533-&&-positive regulation of intracellular signal transduction-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051259-&&-protein oligomerization-%%-GO:0001958-&&-endochondral ossification-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0048014-&&-Tie signaling pathway-%%-GO:0051591-&&-response to cAMP-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0001525-&&-angiogenesis-%%-GO:0050900-&&-leukocyte migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005884-&&-actin filament-%%-GO:0001725-&&-stress fiber-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005902-&&-microvillus|molecular_function-&-1&-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019838-&&-growth factor binding	G:9606:TEK			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	TEK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEK	0.37611852	0.17666667	27	4	FALSE	TEK	TEK	147.68	0	26	0	0.72354393	FALSE	1	TEK	45304	0.06673903
788632	taxon:9606	2.7412951	2.21E-05	177280	1902	nuclear receptor subfamily 2 group F member 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0044323-&&-retinoic acid-responsive element binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity	G:9606:NR2F1				NR2F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR2F1	0.36479108	0.16239316	27	4	FALSE	NR2F1	NR2F1	116.3703704	0	27	0	0.70978415	FALSE	0	NR2F1	33840	0.06660299
788718	taxon:9606	2.70694816	5.97E-06	177124	1902	nuclear receptor subfamily 2 group C member 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048386-&&-positive regulation of retinoic acid receptor signaling pathway-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004872-&&-receptor activity	G:9606:NR2C1				NR2C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR2C1	0.36941971	0.41880342	27	5	FALSE	NR2C1	NR2C1	171.5555556	0	27	0	0.71550864	FALSE	0	NR2C1	12510	0.08728678
788841	taxon:9606	2.61966283	1.04E-04	176775	1902	uridine monophosphate synthetase	gene	biological_process-&-1&-GO:0046134-&&-pyrimidine nucleoside biosynthetic process-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0044205-&&-'de novo' UMP biosynthetic process-%%-GO:0006222-&&-UMP biosynthetic process-%%-GO:0035690-&&-cellular response to drug-%%-GO:0007565-&&-female pregnancy-%%-GO:0007595-&&-lactation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004588-&&-orotate phosphoribosyltransferase activity-%%-GO:0004590-&&-orotidine-5'-phosphate decarboxylase activity	G:9606:UMPS			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	UMPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UMPS	0.38172851	0.06267806	27	4	FALSE	UMPS	UMPS	136.4074074	0	27	0	0.73005619	FALSE	0	UMPS	95818	0.05565402
788966	taxon:9606	2.67969119	2.22E-05	176513	1902	docking protein 2	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0050900-&&-leukocyte migration-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007265-&&-Ras protein signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK2				DOK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK2	0.37317733	0.23666667	27	4	FALSE	DOK2	DOK2	150.4	0	26	0	0.72005147	FALSE	1	DOK2	36544	0.07216138
788987	taxon:9606	2.74255554	3.91E-05	176453	1902	Ras association domain family member 7	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007165-&&-signal transduction-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RASSF7				RASSF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF7	0.36462343	0.12250712	27	4	FALSE	RASSF7	RASSF7	95.62962963	0	27	0	0.70957408	FALSE	0	RASSF7	42342	0.05584812
788988	taxon:9606	2.71435324	2.36E-05	176448	1902	FOS like 1, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034097-&&-response to cytokine-%%-GO:0051412-&&-response to corticosterone-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007296-&&-vitellogenesis-%%-GO:0007612-&&-learning-%%-GO:0061614-&&-pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006935-&&-chemotaxis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0009629-&&-response to gravity-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0006968-&&-cellular defense response-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0042493-&&-response to drug-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0009615-&&-response to virus|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0042734-&&-presynaptic membrane|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:FOSL1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04380-&&-Osteoclast differentiation	FOSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOSL1	0.36841189	0.27635328	27	4	FALSE	FOSL1	FOSL1	131.8888889	0	27	0	0.71427446	FALSE	0	FOSL1	37310	0.06952498
789014	taxon:9606	2.5804317	4.39E-05	176382	1902	elongation factor for RNA polymerase II	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0042796-&&-snRNA transcription from RNA polymerase III promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0032968-&&-positive regulation of transcription elongation from RNA polymerase II promoter|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0035363-&&-histone locus body-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:ELL				ELL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELL	0.38753206	0.20512821	27	4	FALSE	ELL	ELL	184.5185185	0	27	0	0.73659472	FALSE	0	ELL	70108	0.06811095
789234	taxon:9606	2.74917284	4.35E-05	175940	1902	regulator of G-protein signaling 20	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS20				RGS20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS20	0.36374577	0.06837607	27	4	FALSE	RGS20	RGS20	93.11111111	0	27	0	0.70847119	FALSE	0	RGS20	51098	0.05650291
789252	taxon:9606	2.73767134	2.18E-05	175894	1902	tankyrase	gene	biological_process-&-1&-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0051028-&&-mRNA transport-%%-GO:1904743-&&-negative regulation of telomeric DNA binding-%%-GO:0015031-&&-protein transport-%%-GO:0051301-&&-cell division-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:1904908-&&-negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0032210-&&-regulation of telomere maintenance via telomerase-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070212-&&-protein poly-ADP-ribosylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051225-&&-spindle assembly-%%-GO:0070213-&&-protein auto-ADP-ribosylation-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0000242-&&-pericentriolar material-%%-GO:0000922-&&-spindle pole-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005643-&&-nuclear pore-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000775-&&-chromosome, centromeric region|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042393-&&-histone binding	G:9606:TNKS				TNKS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNKS	0.36527394	0.12333333	27	4	FALSE	TNKS	TNKS	106.32	0	26	0	0.71038811	FALSE	1	TNKS	30782	0.06051224
789369	taxon:9606	2.67543721	4.67E-05	175651	1902	Ras association domain family member 9	gene	biological_process-&-1&-GO:0006605-&&-protein targeting-%%-GO:0007165-&&-signal transduction-%%-GO:0016197-&&-endosomal transport|cellular_component-&-1&-GO:0012510-&&-trans-Golgi network transport vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:RASSF9				RASSF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF9	0.37377068	0.12820513	27	4	FALSE	RASSF9	RASSF9	128.1851852	0	27	0	0.72076046	FALSE	0	RASSF9	52300	0.05949676
789383	taxon:9606	2.7677643	3.11E-05	175618	1902	membrane associated guanylate kinase, WW and PDZ domain containing 1	gene	biological_process-&-1&-GO:0070997-&&-neuron death-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0007166-&&-cell surface receptor signaling pathway|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0042995-&&-cell projection-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005912-&&-adherens junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005524-&&-ATP binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0005515-&&-protein binding-%%-GO:0051393-&&-alpha-actinin binding	G:9606:MAGI1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04530-&&-Tight junction-%%-hsa05165-&&-Human papillomavirus infection	MAGI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGI1	0.36130244	0.07692308	27	4	FALSE	MAGI1	MAGI1	88.96296296	0	27	0	0.70537262	FALSE	0	MAGI1	35638	0.05791422
789478	taxon:9606	2.76224988	4.12E-05	175373	1902	guanine deaminase	gene	biological_process-&-1&-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0006147-&&-guanine catabolic process-%%-GO:0007399-&&-nervous system development-%%-GO:0006195-&&-purine nucleotide catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0008892-&&-guanine deaminase activity	G:9606:GDA			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	GDA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GDA	0.36202373	0.14245014	27	4	FALSE	GDA	GDA	88.96296296	0	27	0	0.70629169	FALSE	0	GDA	44802	0.0557412
789508	taxon:9606	2.56751221	8.90E-05	175308	1902	basic leucine zipper and W2 domains 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:BZW1				BZW1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BZW1	0.38948208	0.11396011	27	4	FALSE	BZW1	BZW1	194.3703704	0	27	0	0.73874796	FALSE	0	BZW1	93878	0.06969878
789556	taxon:9606	2.69198046	5.54E-05	175194	1902	nucleoporin 58	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0042306-&&-regulation of protein import into nucleus-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:0051290-&&-protein heterotetramerization-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005643-&&-nuclear pore-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:NUP58			KEGG-&-1&-hsa03013-&&-RNA transport	NUP58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUP58	0.37147372	0.13675214	27	4	FALSE	NUP58	NUP58	119.1481482	0	27	0	0.71800326	FALSE	0	NUP58	56744	0.05904962
789576	taxon:9606	2.55947692	3.36E-05	175150	1902	translocase of outer mitochondrial membrane 70	gene	biological_process-&-1&-GO:0071806-&&-protein transmembrane transport-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0016236-&&-macroautophagy|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005742-&&-mitochondrial outer membrane translocase complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0005515-&&-protein binding	G:9606:TOMM70				TOMM70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM70	0.39070483	0.15954416	27	4	FALSE	TOMM70	TOMM70	210.7037037	0	27	0	0.74008718	FALSE	0	TOMM70	66424	0.07416536
789740	taxon:9606	2.65101623	5.89E-05	174784	1902	adaptor related protein complex 1 mu 2 subunit	gene	biological_process-&-1&-GO:0006903-&&-vesicle targeting-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AP1M2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1M2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1M2	0.37721384	0.16524217	27	5	FALSE	AP1M2	AP1M2	116.8518519	0	27	0	0.72483063	FALSE	0	AP1M2	57538	0.05175331
789785	taxon:9606	2.6981251	2.87E-05	174683	1902	M-phase phosphoprotein 6	gene	biological_process-&-1&-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0000176-&&-nuclear exosome (RNase complex)-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MPHOSPH6			KEGG-&-1&-hsa03018-&&-RNA degradation	MPHOSPH6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPHOSPH6	0.37062774	0.09116809	27	4	FALSE	MPHOSPH6	MPHOSPH6	119.9259259	0	27	0	0.71697915	FALSE	0	MPHOSPH6	44396	0.05950605
789788	taxon:9606	2.81203718	1.95E-05	174679	1902	nuclear transport factor 2	gene	biological_process-&-1&-GO:0071806-&&-protein transmembrane transport-%%-GO:0051028-&&-mRNA transport-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:1904046-&&-negative regulation of vascular endothelial growth factor production-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0090204-&&-protein localization to nuclear pore|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0044613-&&-nuclear pore central transport channel-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008320-&&-protein transmembrane transporter activity	G:9606:NUTF2				NUTF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUTF2	0.35561407	0.11	27	4	FALSE	NUTF2	NUTF2	84.44	0	26	0	0.6979938	FALSE	1	NUTF2	25684	0.06261516
789890	taxon:9606	2.60485269	1.29E-05	174416	1902	SH2B adaptor protein 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0046425-&&-regulation of JAK-STAT cascade-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0008269-&&-JAK pathway signal transduction adaptor activity	G:9606:SH2B2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04910-&&-Insulin signaling pathway	SH2B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2B2	0.38389887	0.30666667	27	4	FALSE	SH2B2	SH2B2	187.76	0	26	0	0.73252455	FALSE	1	SH2B2	30578	0.07409163
789948	taxon:9606	2.53537104	3.89E-05	174273	1902	NCK associated protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0007417-&&-central nervous system development-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:2000601-&&-positive regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0016032-&&-viral process-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0031209-&&-SCAR complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:NCKAP1			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	NCKAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCKAP1	0.39441959	0.16239316	27	4	FALSE	NCKAP1	NCKAP1	225.4444444	0	27	0	0.74410483	FALSE	0	NCKAP1	84214	0.07584427
789964	taxon:9606	2.53820703	5.92E-05	174230	1902	ecdysoneless cell cycle regulator	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0008380-&&-RNA splicing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000045-&&-regulation of G1/S transition of mitotic cell cycle-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0097255-&&-R2TP complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:ECD				ECD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECD	0.3939789	0.0968661	27	4	FALSE	ECD	ECD	195.6296296	0	27	0	0.74363216	FALSE	0	ECD	85292	0.06577159
789987	taxon:9606	2.57145108	2.50E-05	174180	1902	DnaJ heat shock protein family (Hsp40) member C8	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm	G:9606:DNAJC8				DNAJC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC8	0.38888548	0.10541311	27	4	FALSE	DNAJC8	DNAJC8	179.5555556	0	27	0	0.73809149	FALSE	0	DNAJC8	43904	0.06536106
790017	taxon:9606	2.47282181	4.55E-05	174095	1902	caseinolytic mitochondrial matrix peptidase chaperone subunit	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0010952-&&-positive regulation of peptidase activity|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005829-&&-cytosol-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005654-&&-nucleoplasm-%%-GO:0009368-&&-endopeptidase Clp complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0009841-&&-mitochondrial endopeptidase Clp complex-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0016887-&&-ATPase activity-%%-GO:0004176-&&-ATP-dependent peptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0016504-&&-peptidase activator activity	G:9606:CLPX				CLPX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLPX	0.4043963	0.15669516	27	4	FALSE	CLPX	CLPX	287.037037	0	27	0	0.7545297	FALSE	0	CLPX	95824	0.08543445
790061	taxon:9606	2.62738302	5.44E-05	173979	1902	glomulin, FKBP associated protein	gene	biological_process-&-1&-GO:0042692-&&-muscle cell differentiation-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0001570-&&-vasculogenesis-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042327-&&-positive regulation of phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0055105-&&-ubiquitin-protein transferase inhibitor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005171-&&-hepatocyte growth factor receptor binding-%%-GO:0005515-&&-protein binding	G:9606:GLMN				GLMN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLMN	0.38060686	0.11680912	27	4	FALSE	GLMN	GLMN	171.2222222	0	27	0	0.7287695	FALSE	0	GLMN	72486	0.07067506
790088	taxon:9606	2.63368521	3.14E-05	173907	1902	SEC63 homolog, protein translocation regulator	gene	biological_process-&-1&-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0031204-&&-posttranslational protein targeting to membrane, translocation-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:0006620-&&-posttranslational protein targeting to membrane-%%-GO:0001889-&&-liver development-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0006807-&&-nitrogen compound metabolic process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0072001-&&-renal system development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:SEC63			KEGG-&-1&-hsa03060-&&-Protein export-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC63	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC63	0.3796961	0.07977208	27	4	FALSE	SEC63	SEC63	158.4074074	0	27	0	0.72771913	FALSE	0	SEC63	65784	0.06625721
790099	taxon:9606	2.50527808	3.26E-05	173873	1902	proline rich coiled-coil 2C	gene	biological_process-&-1&-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:PRRC2C				PRRC2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRRC2C	0.39915729	0.09401709	27	4	FALSE	PRRC2C	PRRC2C	258.1851852	0	27	0	0.74912032	FALSE	0	PRRC2C	69966	0.08169037
790111	taxon:9606	2.49346148	2.34E-05	173856	1902	salt inducible kinase 2	gene	biological_process-&-1&-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:SIK2			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway	SIK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIK2	0.40104891	0.22792023	27	4	FALSE	SIK2	SIK2	255.8518519	0	27	0	0.75108975	FALSE	0	SIK2	46018	0.07939628
790113	taxon:9606	2.73719868	4.61E-05	173853	1902	PH domain and leucine rich repeat protein phosphatase 1	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0009649-&&-entrainment of circadian clock-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0002667-&&-regulation of T cell anergy-%%-GO:1900744-&&-regulation of p38MAPK cascade-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0090036-&&-regulation of protein kinase C signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PHLPP1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	PHLPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLPP1	0.36533702	0.0997151	27	5	FALSE	PHLPP1	PHLPP1	94.14814815	0	27	0	0.71046689	FALSE	0	PHLPP1	45506	0.05396096
790126	taxon:9606	2.7562628	2.63E-05	173816	1902	ubiquitin specific peptidase 18	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0019785-&&-ISG15-specific protease activity	G:9606:USP18				USP18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP18	0.36281011	0.13105413	27	4	FALSE	USP18	USP18	104.7037037	0	27	0	0.70728953	FALSE	0	USP18	34372	0.06526564
790212	taxon:9606	2.68205451	4.58E-05	173628	1902	zinc finger protein 281	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0010172-&&-embryonic body morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001047-&&-core promoter binding	G:9606:ZNF281				ZNF281	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF281	0.3728485	0.06837607	27	4	FALSE	ZNF281	ZNF281	136.4814815	0	27	0	0.71965758	FALSE	0	ZNF281	57092	0.06493851
790264	taxon:9606	2.62155349	2.58E-05	173483	1902	sperm antigen with calponin homology and coiled-coil domains 1 like	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0016477-&&-cell migration-%%-GO:0030835-&&-negative regulation of actin filament depolymerization-%%-GO:0051301-&&-cell division-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0007155-&&-cell adhesion-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005921-&&-gap junction-%%-GO:0005819-&&-spindle-%%-GO:0031941-&&-filamentous actin-%%-GO:0005829-&&-cytosol-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005815-&&-microtubule organizing center	G:9606:SPECC1L				SPECC1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPECC1L	0.38145321	0.21082621	27	4	FALSE	SPECC1L	SPECC1L	186.9259259	0	27	0	0.72974109	FALSE	0	SPECC1L	46990	0.07681643
790276	taxon:9606	2.78777375	5.88E-05	173462	1902	sirtuin 3	gene	biological_process-&-1&-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0007568-&&-aging-%%-GO:0009060-&&-aerobic respiration-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0034983-&&-peptidyl-lysine deacetylation-%%-GO:0006476-&&-protein deacetylation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0032024-&&-positive regulation of insulin secretion|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0070403-&&-NAD+ binding-%%-GO:0005515-&&-protein binding	G:9606:SIRT3			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer	SIRT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT3	0.35870917	0.03133903	27	4	FALSE	SIRT3	SIRT3	87	0	27	0	0.70203771	FALSE	0	SIRT3	69860	0.06144781
790313	taxon:9606	2.54230345	4.95E-05	173351	1902	protein kinase D2	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0008219-&&-cell death-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0038033-&&-positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0050862-&&-positive regulation of T cell receptor signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0089700-&&-protein kinase D signaling-%%-GO:1901727-&&-positive regulation of histone deacetylase activity-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007155-&&-cell adhesion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:2001028-&&-positive regulation of endothelial cell chemotaxis-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0002250-&&-adaptive immune response-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1902533-&&-positive regulation of intracellular signal transduction-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0045743-&&-positive regulation of fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004697-&&-protein kinase C activity	G:9606:PRKD2			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion	PRKD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKD2	0.39334408	0.11666667	27	4	FALSE	PRKD2	PRKD2	201.96	0	26	0	0.74294942	FALSE	1	PRKD2	71376	0.06830061
790560	taxon:9606	2.53095951	1.27E-05	172138	1902	coatomer protein complex subunit gamma 2	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:COPG2				COPG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPG2	0.39510707	0.30333333	27	4	FALSE	COPG2	COPG2	276.8	0	26	0	0.74484008	FALSE	1	COPG2	35164	0.09143046
790567	taxon:9606	2.63904207	1.49E-05	172120	1902	DnaJ heat shock protein family (Hsp40) member C2	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0051083-&&-'de novo' cotranslational protein folding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0003723-&&-RNA binding	G:9606:DNAJC2				DNAJC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC2	0.37892537	0.10826211	27	4	FALSE	DNAJC2	DNAJC2	174.2592593	0	27	0	0.72682632	FALSE	0	DNAJC2	39512	0.07380717
790582	taxon:9606	2.69292579	2.44E-05	172080	1902	forkhead box P1	gene	biological_process-&-1&-GO:0032680-&&-regulation of tumor necrosis factor production-%%-GO:0035926-&&-chemokine (C-C motif) ligand 2 secretion-%%-GO:1900424-&&-regulation of defense response to bacterium-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0036035-&&-osteoclast development-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050706-&&-regulation of interleukin-1 beta secretion-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0042117-&&-monocyte activation-%%-GO:1901509-&&-regulation of endothelial tube morphogenesis-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:2001182-&&-regulation of interleukin-12 secretion-%%-GO:0042116-&&-macrophage activation-%%-GO:0045655-&&-regulation of monocyte differentiation-%%-GO:0072619-&&-interleukin-21 secretion-%%-GO:1901256-&&-regulation of macrophage colony-stimulating factor production-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0061470-&&-T follicular helper cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060766-&&-negative regulation of androgen receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0046872-&&-metal ion binding	G:9606:FOXP1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	FOXP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXP1	0.37134332	0.11666667	27	4	FALSE	FOXP1	FOXP1	140.88	0	26	0	0.7178457	FALSE	1	FOXP1	39022	0.06866341
790608	taxon:9606	2.63589097	2.21E-05	171772	1902	ADP ribosylation factor like GTPase 6 interacting protein 4	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ARL6IP4				ARL6IP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARL6IP4	0.37937836	0.06333333	27	4	FALSE	ARL6IP4	ARL6IP4	173.4	0	26	0	0.7273515	FALSE	1	ARL6IP4	44060	0.07352316
790660	taxon:9606	2.59020009	1.27E-05	171562	1902	decapping enzyme, scavenger	gene	biological_process-&-1&-GO:0036245-&&-cellular response to menadione-%%-GO:0000290-&&-deadenylation-dependent decapping of nuclear-transcribed mRNA-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0045292-&&-mRNA cis splicing, via spliceosome-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000932-&&-P-body-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0050072-&&-m7G(5')pppN diphosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000340-&&-RNA 7-methylguanosine cap binding	G:9606:DCPS			KEGG-&-1&-hsa03018-&&-RNA degradation	DCPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCPS	0.38607056	0.23666667	27	4	FALSE	DCPS	DCPS	178.76	0	26	0	0.73496665	FALSE	1	DCPS	26988	0.06743116
790771	taxon:9606	2.82369623	1.07E-06	171271	1902	PHD finger protein 20	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0043984-&&-histone H4-K16 acetylation|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071339-&&-MLL1 complex|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046972-&&-histone acetyltransferase activity (H4-K16 specific)-%%-GO:0043995-&&-histone acetyltransferase activity (H4-K5 specific)-%%-GO:0005515-&&-protein binding-%%-GO:0043996-&&-histone acetyltransferase activity (H4-K8 specific)-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PHF20				PHF20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF20	0.35414574	0.5982906	27	4	FALSE	PHF20	PHF20	296.8148148	0	27	0	0.69605063	FALSE	0	PHF20	7208	0.22347724
790777	taxon:9606	2.74381598	4.05E-05	171241	1902	transcription factor Dp family member 3	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:TFDP3				TFDP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFDP3	0.36445593	0.05128205	27	4	FALSE	TFDP3	TFDP3	94.03703704	0	27	0	0.709364	FALSE	0	TFDP3	44618	0.05523909
790791	taxon:9606	2.68441784	4.26E-05	171189	1902	SERTA domain containing 1	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SERTAD1				SERTAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERTAD1	0.37252025	0.07977208	27	4	FALSE	SERTAD1	SERTAD1	131.2962963	0	27	0	0.71926369	FALSE	0	SERTAD1	56296	0.06412139
790799	taxon:9606	2.72396408	3.13E-05	171170	1902	protein kinase C and casein kinase substrate in neurons 1	gene	biological_process-&-1&-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0007015-&&-actin filament organization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0072657-&&-protein localization to membrane-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:1900006-&&-positive regulation of dendrite development-%%-GO:0097320-&&-plasma membrane tubulation|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0030137-&&-COPI-coated vesicle-%%-GO:0043679-&&-axon terminus-%%-GO:0043209-&&-myelin sheath-%%-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding	G:9606:PACSIN1				PACSIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PACSIN1	0.36711204	0.10666667	27	4	FALSE	PACSIN1	PACSIN1	127.16	0	26	0	0.71267265	FALSE	1	PACSIN1	46080	0.070299
790833	taxon:9606	2.80998897	2.30E-05	171012	1902	TP53RK binding protein	gene	biological_process-&-1&-GO:0008033-&&-tRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:TPRKB	TPRKB	TRUE		TPRKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPRKB	0.35587328	0.26495726	27	4	FALSE	TPRKB	TPRKB	77.44444444	0	27	0	0.69833517	FALSE	0	TPRKB	29472	0.05775454
791047	taxon:9606	2.80825587	3.48E-05	170262	1902	COMM domain containing 4	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COMMD4				COMMD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD4	0.35609291	0.12250712	27	4	FALSE	COMMD4	COMMD4	75.11111111	0	27	0	0.69862402	FALSE	0	COMMD4	36994	0.05654787
791143	taxon:9606	2.81172207	2.04E-05	169895	1902	tRNA methyltransferase 1	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0002940-&&-tRNA N2-guanine methylation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004809-&&-tRNA (guanine-N2-)-methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000049-&&-tRNA binding	G:9606:TRMT1				TRMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT1	0.35565393	0.13390313	27	4	FALSE	TRMT1	TRMT1	78.92592593	0	27	0	0.69804632	FALSE	0	TRMT1	23678	0.05994189
791230	taxon:9606	2.68032141	1.53E-05	169648	1902	ubiquitin family domain containing 1	gene	molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0045296-&&-cadherin binding	G:9606:UBFD1				UBFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBFD1	0.37308958	0.26210826	27	4	FALSE	UBFD1	UBFD1	143.7037037	0	27	0	0.71994643	FALSE	0	UBFD1	27248	0.0688896
791458	taxon:9606	2.69780999	2.02E-05	168563	1902	nucleolar complex associated 4 homolog	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030692-&&-Noc4p-Nop14p complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NOC4L				NOC4L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOC4L	0.37067103	0.06837607	27	4	FALSE	NOC4L	NOC4L	138.4444444	0	27	0	0.71703167	FALSE	0	NOC4L	36928	0.06906907
791845	taxon:9606	2.63321254	1.27E-04	182986	1902	angio associated migratory cell protein	gene	biological_process-&-1&-GO:0014909-&&-smooth muscle cell migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0042273-&&-ribosomal large subunit biogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0008201-&&-heparin binding	G:9606:AAMP				AAMP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AAMP	0.37976426	0.06552707	27	4	FALSE	AAMP	AAMP	127.3703704	0	27	0	0.72779791	FALSE	0	AAMP	120276	0.05328053
792023	taxon:9606	2.69544667	2.47E-05	182722	1902	PR/SET domain 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:1990654-&&-sebum secreting cell proliferation-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0035904-&&-aorta development-%%-GO:0051136-&&-regulation of NK T cell differentiation-%%-GO:0031665-&&-negative regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0060576-&&-intestinal epithelial cell development-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007281-&&-germ cell development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0003170-&&-heart valve development-%%-GO:0032823-&&-regulation of natural killer cell differentiation-%%-GO:0001893-&&-maternal placenta development-%%-GO:0003281-&&-ventricular septum development-%%-GO:0001763-&&-morphogenesis of a branching structure-%%-GO:0009791-&&-post-embryonic development-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0045165-&&-cell fate commitment-%%-GO:0032259-&&-methylation-%%-GO:0060707-&&-trophoblast giant cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033082-&&-regulation of extrathymic T cell differentiation-%%-GO:0042462-&&-eye photoreceptor cell development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:PRDM1				PRDM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDM1	0.37099603	0.11333333	27	4	FALSE	PRDM1	PRDM1	151.36	0	26	0	0.71742556	FALSE	1	PRDM1	42652	0.07503968
792037	taxon:9606	2.45296991	3.50E-05	182702	1902	BMX non-receptor tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0007155-&&-cell adhesion-%%-GO:0007498-&&-mesoderm development-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0001865-&&-NK T cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:BMX				BMX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMX	0.40766909	0.24501425	27	4	FALSE	BMX	BMX	234.5185185	0	27	0	0.75783835	FALSE	0	BMX	78988	0.06742722
792195	taxon:9606	2.72569718	2.77E-05	182448	1902	aryl hydrocarbon receptor nuclear translocator like	gene	biological_process-&-1&-GO:0090403-&&-oxidative stress-induced premature senescence-%%-GO:2001016-&&-positive regulation of skeletal muscle cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis-%%-GO:2000772-&&-regulation of cellular senescence-%%-GO:0042634-&&-regulation of hair cycle-%%-GO:0051775-&&-response to redox state-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:2000074-&&-regulation of type B pancreatic cell development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0060137-&&-maternal process involved in parturition-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0033391-&&-chromatoid body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003677-&&-DNA binding-%%-GO:0017162-&&-aryl hydrocarbon receptor binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding	G:9606:ARNTL	ARNTL	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04710-&&-Circadian rhythm	ARNTL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARNTL	0.36687861	0.27065527	27	4	FALSE	ARNTL	ARNTL	137.4074074	0	27	0	0.7123838	FALSE	0	ARNTL	41094	0.07425425
792242	taxon:9606	2.87805262	3.09E-06	165978	1902	ribosomal protein S10 pseudogene 5	gene	biological_process-&-1&-GO:0000028-&&-ribosomal small subunit assembly|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS10P5				RPS10P5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS10P5	0.34745716	0.61253561	27	5	FALSE	RPS10P5	RPS10P5	143.1851852	0	27	0	0.68699123	FALSE	0	RPS10P5	6382	0.14318022
792502	taxon:9606	2.85883094	1.45E-05	165513	1902	vasorin	gene	biological_process-&-1&-GO:0071461-&&-cellular response to redox state-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:VASN				VASN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VASN	0.34979333	0.17378917	27	5	FALSE	VASN	VASN	104.7407407	0	27	0	0.69019484	FALSE	0	VASN	20876	0.09581468
792591	taxon:9606	2.51173783	2.43E-05	181754	1902	desmoglein 1	gene	biological_process-&-1&-GO:0016339-&&-calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0031424-&&-keratinization-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0070268-&&-cornification-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0032570-&&-response to progesterone-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0050821-&&-protein stabilization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007043-&&-cell-cell junction assembly|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0030057-&&-desmosome-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0001533-&&-cornified envelope|molecular_function-&-1&-GO:0045295-&&-gamma-catenin binding-%%-GO:0005515-&&-protein binding-%%-GO:0015643-&&-toxic substance binding-%%-GO:0005509-&&-calcium ion binding	G:9606:DSG1			KEGG-&-1&-hsa05150-&&-Staphylococcus aureus infection	DSG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSG1	0.39813072	0.19373219	27	4	FALSE	DSG1	DSG1	273.8148148	0	27	0	0.7480437	FALSE	0	DSG1	56728	0.08752917
792592	taxon:9606	2.58767922	8.31E-05	181751	1902	TSC22 domain family member 3	gene	biological_process-&-1&-GO:0070236-&&-negative regulation of activation-induced cell death of T cells-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043426-&&-MRF binding	G:9606:TSC22D3				TSC22D3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSC22D3	0.38644666	0.19	27	4	FALSE	TSC22D3	TSC22D3	214.92	0	26	0	0.7353868	FALSE	1	TSC22D3	81570	0.0810566
792627	taxon:9606	2.912242	9.03E-05	181698	1902	lysophosphatidic acid receptor 1	gene	biological_process-&-1&-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0021549-&&-cerebellum development-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0032060-&&-bleb assembly-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0071673-&&-positive regulation of smooth muscle cell chemotaxis-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0071453-&&-cellular response to oxygen levels-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1904566-&&-cellular response to 1-oleoyl-sn-glycerol 3-phosphate-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0022038-&&-corpus callosum development-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0042552-&&-myelination-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0021554-&&-optic nerve development-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0060999-&&-positive regulation of dendritic spine development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005768-&&-endosome-%%-GO:0009986-&&-cell surface-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0035727-&&-lysophosphatidic acid binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0070915-&&-lysophosphatidic acid receptor activity	G:9606:LPAR1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	LPAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPAR1	0.34337806	0.01709402	27	4	FALSE	LPAR1	LPAR1	36.18518519	0	27	0	0.681293	FALSE	0	LPAR1	83524	0.04812807
792758	taxon:9606	2.59319363	1.96E-05	181430	1902	FER tyrosine kinase	gene	biological_process-&-1&-GO:0044331-&&-cell-cell adhesion mediated by cadherin-%%-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0036119-&&-response to platelet-derived growth factor-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0010591-&&-regulation of lamellipodium assembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0033007-&&-negative regulation of mast cell activation involved in immune response-%%-GO:0006935-&&-chemotaxis-%%-GO:0008283-&&-cell proliferation-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0042503-&&-tyrosine phosphorylation of Stat3 protein-%%-GO:0038109-&&-Kit signaling pathway-%%-GO:0050904-&&-diapedesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0035426-&&-extracellular matrix-cell signaling-%%-GO:0036006-&&-cellular response to macrophage colony-stimulating factor stimulus-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0038028-&&-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005938-&&-cell cortex-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0008289-&&-lipid binding	G:9606:FER			KEGG-&-1&-hsa04520-&&-Adherens junction	FER	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FER	0.38562489	0.27666667	27	5	FALSE	FER	FER	190.88	0	26	0	0.73446773	FALSE	1	FER	31106	0.07289534
792828	taxon:9606	2.55664093	3.49E-05	181298	1902	erythrocyte membrane protein band 4.1 like 2	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008180-&&-COP9 signalosome-%%-GO:0008091-&&-spectrin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0042731-&&-PH domain binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:EPB41L2				EPB41L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41L2	0.39113823	0.18518519	27	4	FALSE	EPB41L2	EPB41L2	203.7777778	0	27	0	0.74055984	FALSE	0	EPB41L2	61370	0.07156154
793055	taxon:9606	2.58720655	7.14E-05	164436	1902	ankyrin repeat and SOCS box containing 6	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ASB6				ASB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB6	0.38651726	0.14814815	27	4	FALSE	ASB6	ASB6	170.4444444	0	27	0	0.73546557	FALSE	0	ASB6	93874	0.06428701
793083	taxon:9606	2.8074681	2.05E-05	180772	1902	nuclear receptor subfamily 5 group A member 2	gene	biological_process-&-1&-GO:0009790-&&-embryo development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0061113-&&-pancreas morphogenesis-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008206-&&-bile acid metabolic process-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0042592-&&-homeostatic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0009888-&&-tissue development|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005543-&&-phospholipid binding	G:9606:NR5A2			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young	NR5A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR5A2	0.35619283	0.09	27	4	FALSE	NR5A2	NR5A2	89.28	0	26	0	0.69875532	FALSE	1	NR5A2	26480	0.06668666
793156	taxon:9606	2.67055302	2.63E-05	180620	1902	G protein subunit alpha 12	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0030154-&&-cell differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0032006-&&-regulation of TOR signaling|cellular_component-&-1&-GO:0031526-&&-brush border membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031752-&&-D5 dopamine receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding	G:9606:GNA12			KEGG-&-1&-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	GNA12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNA12	0.37445428	0.12333333	27	5	FALSE	GNA12	GNA12	127.2	0	26	0	0.7215745	FALSE	1	GNA12	38310	0.06000944
793232	taxon:9606	2.57854104	1.53E-04	180494	1902	heparan sulfate proteoglycan 2	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:HSPG2	HSPG2	TRUE	KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05161-&&-Hepatitis B	HSPG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPG2	0.3878162	0.07977208	27	4	FALSE	HSPG2	HSPG2	162.1111111	0	27	0	0.73690983	FALSE	0	HSPG2	148718	0.06037866
793320	taxon:9606	2.60548291	5.50E-05	163933	1902	exocyst complex component 8	gene	biological_process-&-1&-GO:0016241-&&-regulation of macroautophagy-%%-GO:0051601-&&-exocyst localization-%%-GO:0007032-&&-endosome organization-%%-GO:0015031-&&-protein transport-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0001927-&&-exocyst assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030426-&&-growth cone-%%-GO:0005886-&&-plasma membrane-%%-GO:0000145-&&-exocyst-%%-GO:0005770-&&-late endosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0017160-&&-Ral GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:EXOC8				EXOC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC8	0.38380601	0.2022792	27	4	FALSE	EXOC8	EXOC8	141.037037	0	27	0	0.73241952	FALSE	0	EXOC8	56122	0.0550707
793324	taxon:9606	2.69198046	6.61E-06	180318	1902	HIC ZBTB transcriptional repressor 1	gene	biological_process-&-1&-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0000785-&&-chromatin-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HIC1				HIC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIC1	0.37147372	0.28333333	27	5	FALSE	HIC1	HIC1	169.4	0	26	0	0.71800326	FALSE	1	HIC1	16872	0.08381989
793354	taxon:9606	2.77926579	2.61E-05	180251	1902	forkhead box A1	gene	biological_process-&-1&-GO:0060528-&&-secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:1902691-&&-respiratory basal cell differentiation-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0060741-&&-prostate gland stromal morphogenesis-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0032355-&&-response to estradiol-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0048665-&&-neuron fate specification-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:0060738-&&-epithelial-mesenchymal signaling involved in prostate gland development-%%-GO:0061144-&&-alveolar secondary septum development-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0060743-&&-epithelial cell maturation involved in prostate gland development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005902-&&-microvillus-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:FOXA1				FOXA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXA1	0.35980726	0.07977208	27	4	FALSE	FOXA1	FOXA1	93.96296296	0	27	0	0.7034557	FALSE	0	FOXA1	37584	0.06099793
787064	taxon:9606	2.69450134	2.58E-04	180134	1902	interferon alpha and beta receptor subunit 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0009615-&&-response to virus-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0051607-&&-defense response to virus-%%-GO:0045351-&&-type I interferon biosynthetic process-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0042110-&&-T cell activation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0019962-&&-type I interferon binding-%%-GO:0004905-&&-type I interferon receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004920-&&-interleukin-10 receptor activity	G:9606:IFNAR1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	IFNAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNAR1	0.37112618	0.23384615	26	5	FALSE	IFNAR1	IFNAR1	138.3461539	0	26	0	0.71758311	FALSE	0	IFNAR1	432898	0.07011624
787106	taxon:9606	2.83787616	6.47E-05	180050	1902	interleukin 4 receptor	gene	biological_process-&-1&-GO:0042832-&&-defense response to protozoan-%%-GO:0002532-&&-production of molecular mediator involved in inflammatory response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:1990834-&&-response to odorant-%%-GO:0007165-&&-signal transduction-%%-GO:0035771-&&-interleukin-4-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0030728-&&-ovulation-%%-GO:0043627-&&-response to estrogen-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0090197-&&-positive regulation of chemokine secretion-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0002639-&&-positive regulation of immunoglobulin production-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0045626-&&-negative regulation of T-helper 1 cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding-%%-GO:0004913-&&-interleukin-4 receptor activity	G:9606:IL4R			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL4R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL4R	0.35237619	0.17753623	26	4	FALSE	IL4R	IL4R	79.625	0	25	0	0.69368731	FALSE	1	IL4R	116176	0.07032862
787248	taxon:9606	2.83960926	5.64E-05	179800	1902	integrin subunit alpha 2	gene	biological_process-&-1&-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0014075-&&-response to amine-%%-GO:0014850-&&-response to muscle activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030879-&&-mammary gland development-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0008283-&&-cell proliferation-%%-GO:0007565-&&-female pregnancy-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0071107-&&-response to parathyroid hormone-%%-GO:0051971-&&-positive regulation of transmission of nerve impulse-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0042493-&&-response to drug-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0033343-&&-positive regulation of collagen binding-%%-GO:0006971-&&-hypotonic response-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0031346-&&-positive regulation of cell projection organization-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0007596-&&-blood coagulation-%%-GO:0043589-&&-skin morphogenesis-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007155-&&-cell adhesion-%%-GO:0038065-&&-collagen-activated signaling pathway-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0006929-&&-substrate-dependent cell migration-%%-GO:0002687-&&-positive regulation of leukocyte migration-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0033591-&&-response to L-ascorbic acid-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045178-&&-basal part of cell-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0030424-&&-axon-%%-GO:0043679-&&-axon terminus-%%-GO:0034666-&&-integrin alpha2-beta1 complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043236-&&-laminin binding-%%-GO:0098639-&&-collagen binding involved in cell-matrix adhesion-%%-GO:0038064-&&-collagen receptor activity-%%-GO:0005518-&&-collagen binding-%%-GO:0032403-&&-protein complex binding	G:9606:ITGA2			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04145-&&-Phagosome-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)	ITGA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA2	0.35216113	0.06521739	26	4	FALSE	ITGA2	ITGA2	65.16666667	0	25	0	0.69339846	FALSE	1	ITGA2	52208	0.05913856
787487	taxon:9606	2.75421459	1.84E-05	179345	1902	AF4/FMR2 family member 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:AFF1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	AFF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AFF1	0.36307992	0.24275362	26	5	FALSE	AFF1	AFF1	120.2083333	0	25	0	0.7076309	FALSE	1	AFF1	28330	0.07207883
787581	taxon:9606	2.62344415	3.44E-05	179144	1902	neurofilament medium	gene	biological_process-&-1&-GO:0033693-&&-neurofilament bundle assembly-%%-GO:0061564-&&-axon development|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0005883-&&-neurofilament|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:NEFM			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	NEFM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEFM	0.38117831	0.06769231	26	4	FALSE	NEFM	NEFM	161.7692308	0	26	0	0.72942598	FALSE	0	NEFM	52374	0.06617276
787660	taxon:9606	2.67228612	9.52E-05	179002	1902	nucleobindin 1	gene	biological_process-&-1&-GO:1903533-&&-regulation of protein targeting-%%-GO:0072718-&&-response to cisplatin|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0098547-&&-lumenal side of Golgi membrane-%%-GO:0005769-&&-early endosome-%%-GO:0090498-&&-extrinsic component of Golgi membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0001965-&&-G-protein alpha-subunit binding	G:9606:NUCB1				NUCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUCB1	0.37421143	0.08615385	26	4	FALSE	NUCB1	NUCB1	115.9615385	0	26	0	0.72128565	FALSE	0	NUCB1	88530	0.05500512
787731	taxon:9606	2.54923586	2.04E-05	178863	1902	DNA polymerase eta	gene	biological_process-&-1&-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0070987-&&-error-free translesion synthesis-%%-GO:0010225-&&-response to UV-C-%%-GO:0006290-&&-pyrimidine dimer repair-%%-GO:0006260-&&-DNA replication-%%-GO:0071494-&&-cellular response to UV-C-%%-GO:0006281-&&-DNA repair-%%-GO:0006282-&&-regulation of DNA repair-%%-GO:0019985-&&-translesion synthesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity	G:9606:POLH			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance	POLH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLH	0.39227441	0.21014493	26	4	FALSE	POLH	POLH	213.9166667	0	25	0	0.74179402	FALSE	1	POLH	38504	0.07418488
787972	taxon:9606	2.6399874	1.16E-04	162096	1902	laminin subunit alpha 1	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0045995-&&-regulation of embryonic development|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005604-&&-basement membrane-%%-GO:0005606-&&-laminin-1 complex-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005608-&&-laminin-3 complex-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding	G:9606:LAMA1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	LAMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMA1	0.37878969	0.05230769	26	4	FALSE	LAMA1	LAMA1	121.0384615	0	26	0	0.72666877	FALSE	0	LAMA1	101424	0.05262451
788113	taxon:9606	2.66314794	6.29E-05	178218	1902	protein tyrosine phosphatase, non-receptor type 3	gene	biological_process-&-1&-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0097421-&&-liver regeneration-%%-GO:0098902-&&-regulation of membrane depolarization during action potential-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0001784-&&-phosphotyrosine binding	G:9606:PTPN3				PTPN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN3	0.37549547	0.08615385	26	4	FALSE	PTPN3	PTPN3	157.9615385	0	26	0	0.72280868	FALSE	0	PTPN3	66396	0.07243148
788193	taxon:9606	2.69481645	1.51E-05	178100	1902	lysine demethylase 5A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:1901726-&&-negative regulation of histone deacetylase activity-%%-GO:0008584-&&-male gonad development-%%-GO:0034720-&&-histone H3-K4 demethylation|cellular_component-&-1&-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0005515-&&-protein binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding	G:9606:KDM5A				KDM5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM5A	0.37108279	0.24307692	26	5	FALSE	KDM5A	KDM5A	177.1153846	0	26	0	0.71753059	FALSE	0	KDM5A	26368	0.08734528
788331	taxon:9606	2.673389	7.77E-05	177868	1902	serpin family B member 3	gene	biological_process-&-1&-GO:0038001-&&-paracrine signaling-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0010950-&&-positive regulation of endopeptidase activity-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0035425-&&-autocrine signaling-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043508-&&-negative regulation of JUN kinase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0031982-&&-vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity	G:9606:SERPINB3			KEGG-&-1&-hsa05146-&&-Amoebiasis	SERPINB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB3	0.37405705	0.07692308	26	4	FALSE	SERPINB3	SERPINB3	143.4230769	0	26	0	0.72110183	FALSE	0	SERPINB3	100786	0.06783151
788339	taxon:9606	2.81487317	3.16E-05	177846	1902	sterol carrier protein 2	gene	biological_process-&-1&-GO:0033540-&&-fatty acid beta-oxidation using acyl-CoA oxidase-%%-GO:0007031-&&-peroxisome organization-%%-GO:0006694-&&-steroid biosynthetic process-%%-GO:0015914-&&-phospholipid transport-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:1901373-&&-lipid hydroperoxide transport-%%-GO:0015918-&&-sterol transport-%%-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0032385-&&-positive regulation of intracellular cholesterol transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0033814-&&-propanoyl-CoA C-acyltransferase activity-%%-GO:0000062-&&-fatty-acyl-CoA binding-%%-GO:0050632-&&-propionyl-CoA C2-trimethyltridecanoyltransferase activity-%%-GO:0015248-&&-sterol transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0070538-&&-oleic acid binding-%%-GO:0036042-&&-long-chain fatty acyl-CoA binding-%%-GO:0005102-&&-receptor binding	G:9606:SCP2			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa01212-&&-Fatty acid metabolism	SCP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCP2	0.35525579	0.07384615	26	5	FALSE	SCP2	SCP2	72.46153846	0	26	0	0.69752114	FALSE	0	SCP2	31446	0.05619691
788405	taxon:9606	2.70868127	2.42E-05	177731	1902	aurora kinase C	gene	biological_process-&-1&-GO:0051256-&&-mitotic spindle midzone assembly-%%-GO:0048599-&&-oocyte development-%%-GO:0035404-&&-histone-serine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0000910-&&-cytokinesis-%%-GO:0016570-&&-histone modification-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000793-&&-condensed chromosome-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0005876-&&-spindle microtubule-%%-GO:0005819-&&-spindle-%%-GO:0032133-&&-chromosome passenger complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0051233-&&-spindle midzone-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0035174-&&-histone serine kinase activity-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:AURKC				AURKC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AURKC	0.36918334	0.28307692	26	4	FALSE	AURKC	AURKC	247.8846154	0	26	0	0.71521979	FALSE	0	AURKC	56454	0.12794024
788569	taxon:9606	2.67638254	2.07E-05	177416	1902	TATA-box binding protein associated factor 5	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006352-&&-DNA-templated transcription, initiation-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0016573-&&-histone acetylation-%%-GO:0006325-&&-chromatin organization|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:TAF5			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF5	0.37363866	0.36615385	26	4	FALSE	TAF5	TAF5	139.5	0	26	0	0.72060291	FALSE	0	TAF5	37558	0.06455345
788808	taxon:9606	2.54198834	2.92E-05	176835	1902	thioredoxin reductase 1	gene	biological_process-&-1&-GO:0000305-&&-response to oxygen radical-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0007165-&&-signal transduction-%%-GO:0001887-&&-selenium compound metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004791-&&-thioredoxin-disulfide reductase activity-%%-GO:0098625-&&-methylselenol reductase activity-%%-GO:0098626-&&-methylseleninic acid reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:TXNRD1			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa00450-&&-Selenocompound metabolism-%%-hsa05225-&&-Hepatocellular carcinoma	TXNRD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNRD1	0.39339284	0.11076923	26	4	FALSE	TXNRD1	TXNRD1	197.1153846	0	26	0	0.74300194	FALSE	0	TXNRD1	49124	0.06708499
789048	taxon:9606	2.69465889	6.47E-05	176293	1902	multiple PDZ domain crumbs cell polarity complex component	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:MPDZ			KEGG-&-1&-hsa04530-&&-Tight junction	MPDZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPDZ	0.37110448	0.0615942	26	4	FALSE	MPDZ	MPDZ	117.0833333	0	25	0	0.71755685	FALSE	1	MPDZ	59658	0.05805569
789102	taxon:9606	2.56215535	2.47E-05	176195	1902	eukaryotic translation initiation factor 2B subunit delta	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0051716-&&-cellular response to stimulus-%%-GO:0009749-&&-response to glucose-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0006417-&&-regulation of translation-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0006413-&&-translational initiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003743-&&-translation initiation factor activity	G:9606:EIF2B4			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2B4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2B4	0.3902964	0.29347826	26	4	FALSE	EIF2B4	EIF2B4	216	0	25	0	0.73964078	FALSE	1	EIF2B4	51600	0.07624426
789115	taxon:9606	2.71844966	2.75E-05	176168	1902	HECT and RLD domain containing E3 ubiquitin protein ligase family member 1	gene	biological_process-&-1&-GO:0010507-&&-negative regulation of autophagy-%%-GO:0021702-&&-cerebellar Purkinje cell differentiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006810-&&-transport-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0031175-&&-neuron projection development-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity	G:9606:HERC1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HERC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC1	0.36785673	0.05797101	26	5	FALSE	HERC1	HERC1	114.5833333	0	25	0	0.71359172	FALSE	1	HERC1	36622	0.06205866
789132	taxon:9606	2.52843863	2.41E-05	176140	1902	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0048730-&&-epidermis morphogenesis-%%-GO:0008104-&&-protein localization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0070831-&&-basement membrane assembly-%%-GO:0042311-&&-vasodilation-%%-GO:0021915-&&-neural tube development-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0060425-&&-lung morphogenesis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030867-&&-rough endoplasmic reticulum membrane|molecular_function-&-1&-GO:0033823-&&-procollagen glucosyltransferase activity-%%-GO:0008475-&&-procollagen-lysine 5-dioxygenase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0050211-&&-procollagen galactosyltransferase activity	G:9606:PLOD3			KEGG-&-1&-hsa00514-&&-Other types of O-glycan biosynthesis-%%-hsa00310-&&-Lysine degradation	PLOD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLOD3	0.395501	0.23188406	26	4	FALSE	PLOD3	PLOD3	272.8333333	0	25	0	0.74526023	FALSE	1	PLOD3	54316	0.09022494
789204	taxon:9606	2.7513786	5.06E-05	176015	1902	potassium voltage-gated channel subfamily A regulatory beta subunit 2	gene	biological_process-&-1&-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0050905-&&-neuromuscular process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0070995-&&-NADPH oxidation-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0035579-&&-specific granule membrane-%%-GO:0005874-&&-microtubule-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:1990031-&&-pinceau fiber-%%-GO:0005829-&&-cytosol-%%-GO:0043679-&&-axon terminus-%%-GO:0016020-&&-membrane-%%-GO:0044224-&&-juxtaparanode region of axon|molecular_function-&-1&-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity	G:9606:KCNAB2				KCNAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNAB2	0.36345416	0.03623188	26	4	FALSE	KCNAB2	KCNAB2	120.1666667	0	25	0	0.70810357	FALSE	1	KCNAB2	51604	0.07358974
789211	taxon:9606	2.65101623	3.14E-05	175995	1902	calcium/calmodulin dependent protein kinase I	gene	biological_process-&-1&-GO:1901985-&&-positive regulation of protein acetylation-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0007049-&&-cell cycle-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0051147-&&-regulation of muscle cell differentiation-%%-GO:2000615-&&-regulation of histone H3-K9 acetylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0051835-&&-positive regulation of synapse structural plasticity-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060143-&&-positive regulation of syncytium formation by plasma membrane fusion|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:CAMK1			KEGG-&-1&-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	CAMK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK1	0.37721384	0.07608696	26	4	FALSE	CAMK1	CAMK1	138.9583333	0	25	0	0.72483063	FALSE	1	CAMK1	48620	0.06130374
789347	taxon:9606	2.62391681	3.39E-05	175688	1902	cyclin B2	gene	biological_process-&-1&-GO:0048538-&&-thymus development-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0040007-&&-growth-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CCNB2			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	CCNB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNB2	0.38110964	0.15076923	26	4	FALSE	CCNB2	CCNB2	162.5769231	0	26	0	0.7293472	FALSE	0	CCNB2	51924	0.066435
789371	taxon:9606	2.6897747	1.19E-04	175644	1902	death effector domain containing	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:DEDD				DEDD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEDD	0.37177835	0.11231884	26	4	FALSE	DEDD	DEDD	122.375	0	25	0	0.71837088	FALSE	1	DEDD	115978	0.06011231
789431	taxon:9606	2.73199937	4.29E-05	175493	1902	IST1, ESCRT-III associated factor	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0051301-&&-cell division-%%-GO:0019076-&&-viral release from host cell-%%-GO:1904903-&&-ESCRT III complex disassembly-%%-GO:0015031-&&-protein transport-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0000910-&&-cytokinesis-%%-GO:0048672-&&-positive regulation of collateral sprouting-%%-GO:0009838-&&-abscission-%%-GO:0046745-&&-viral capsid secondary envelopment-%%-GO:0008104-&&-protein localization-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0090543-&&-Flemming body|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0090541-&&-MIT domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0045296-&&-cadherin binding	G:9606:IST1			KEGG-&-1&-hsa04144-&&-Endocytosis	IST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IST1	0.3660323	0.11384615	26	4	FALSE	IST1	IST1	131.6153846	0	26	0	0.71133344	FALSE	0	IST1	50542	0.07337972
789442	taxon:9606	2.86182448	3.61E-05	175463	1902	glyoxylate and hydroxypyruvate reductase	gene	biological_process-&-1&-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0051259-&&-protein oligomerization-%%-GO:0007588-&&-excretion-%%-GO:0043648-&&-dicarboxylic acid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008152-&&-metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031406-&&-carboxylic acid binding-%%-GO:0030267-&&-glyoxylate reductase (NADP) activity-%%-GO:0008465-&&-glycerate dehydrogenase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0016618-&&-hydroxypyruvate reductase activity-%%-GO:0051287-&&-NAD binding-%%-GO:0070402-&&-NADPH binding	G:9606:GRHPR			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	GRHPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRHPR	0.34942744	0.06153846	26	4	FALSE	GRHPR	GRHPR	58.07692308	0	26	0	0.68969592	FALSE	0	GRHPR	34628	0.05518076
789800	taxon:9606	2.72427919	3.89E-05	174632	1902	sprouty RTK signaling antagonist 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0001759-&&-organ induction-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0001656-&&-metanephros development-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0001657-&&-ureteric bud development-%%-GO:0051387-&&-negative regulation of neurotrophin TRK receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPRY1				SPRY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRY1	0.36706957	0.22461538	26	4	FALSE	SPRY1	SPRY1	123.4615385	0	26	0	0.71262014	FALSE	0	SPRY1	62100	0.06910587
789884	taxon:9606	2.83582795	2.87E-05	174432	1902	aldo-keto reductase family 1 member A1	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0046185-&&-aldehyde catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0019640-&&-glucuronate catabolic process to xylulose 5-phosphate-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0042840-&&-D-glucuronate catabolic process-%%-GO:0019853-&&-L-ascorbic acid biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0005515-&&-protein binding-%%-GO:0047939-&&-L-glucuronate reductase activity	G:9606:AKR1A1			KEGG-&-1&-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis	AKR1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1A1	0.3526307	0.18769231	26	4	FALSE	AKR1A1	AKR1A1	86.23076923	0	26	0	0.69402867	FALSE	0	AKR1A1	38244	0.07313248
789905	taxon:9606	2.63478809	4.40E-05	174394	1902	thioredoxin interacting protein	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0051782-&&-negative regulation of cell division-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0071228-&&-cellular response to tumor cell-%%-GO:0006606-&&-protein import into nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009749-&&-response to glucose-%%-GO:0032570-&&-response to progesterone-%%-GO:0051592-&&-response to calcium ion-%%-GO:0007049-&&-cell cycle-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0032355-&&-response to estradiol-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TXNIP	TXNIP	TRUE	KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	TXNIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNIP	0.37953716	0.0942029	26	4	FALSE	TXNIP	TXNIP	160	0	25	0	0.72753532	FALSE	1	TXNIP	57094	0.06785209
789965	taxon:9606	2.7346778	8.21E-05	174225	1902	V-set and immunoglobulin domain containing 4	gene	biological_process-&-1&-GO:0006957-&&-complement activation, alternative pathway-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0042130-&&-negative regulation of T cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:VSIG4			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	VSIG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VSIG4	0.36567379	0.02769231	26	5	FALSE	VSIG4	VSIG4	88.19230769	0	26	0	0.71088703	FALSE	0	VSIG4	64234	0.04974417
790071	taxon:9606	2.4759729	5.55E-05	173947	1902	WD repeat domain 6	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:WDR6				WDR6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR6	0.40388164	0.11692308	26	4	FALSE	WDR6	WDR6	283.0769231	0	26	0	0.75400452	FALSE	0	WDR6	93228	0.08457397
790187	taxon:9606	2.59272097	4.42E-05	173691	1902	golgi associated, gamma adaptin ear containing, ARF binding protein 2	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0061024-&&-membrane organization-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0030131-&&-clathrin adaptor complex-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0010008-&&-endosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0030306-&&-ADP-ribosylation factor binding-%%-GO:0005515-&&-protein binding	G:9606:GGA2			KEGG-&-1&-hsa04142-&&-Lysosome	GGA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GGA2	0.38569519	0.17028986	26	4	FALSE	GGA2	GGA2	168.7083333	0	25	0	0.7345465	FALSE	1	GGA2	55924	0.06459849
790204	taxon:9606	2.48968016	3.62E-05	173645	1902	cytoplasmic linker associated protein 2	gene	biological_process-&-1&-GO:1903690-&&-negative regulation of wound healing, spreading of epidermal cells-%%-GO:1904261-&&-positive regulation of basement membrane assembly involved in embryonic body morphogenesis-%%-GO:0032886-&&-regulation of microtubule-based process-%%-GO:0051301-&&-cell division-%%-GO:0007030-&&-Golgi organization-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0031110-&&-regulation of microtubule polymerization or depolymerization-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0031023-&&-microtubule organizing center organization-%%-GO:0006903-&&-vesicle targeting-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0010458-&&-exit from mitosis-%%-GO:0010470-&&-regulation of gastrulation-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0090091-&&-positive regulation of extracellular matrix disassembly-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0007020-&&-microtubule nucleation-%%-GO:0090002-&&-establishment of protein localization to plasma membrane|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005828-&&-kinetochore microtubule-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0031252-&&-cell leading edge-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005938-&&-cell cortex-%%-GO:0045180-&&-basal cortex-%%-GO:0000776-&&-kinetochore-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0072686-&&-mitotic spindle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0002162-&&-dystroglycan binding-%%-GO:0008017-&&-microtubule binding	G:9606:CLASP2				CLASP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLASP2	0.40165802	0.11692308	26	4	FALSE	CLASP2	CLASP2	243	0	26	0	0.75171997	FALSE	0	CLASP2	75248	0.07437705
790214	taxon:9606	2.674807	2.95E-05	173612	1902	septin 6	gene	biological_process-&-1&-GO:0000910-&&-cytokinesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0016032-&&-viral process-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0031105-&&-septin complex-%%-GO:0005819-&&-spindle-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005940-&&-septin ring-%%-GO:0032173-&&-septin collar-%%-GO:0030496-&&-midbody-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0043679-&&-axon terminus-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0097227-&&-sperm annulus|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:SEPT6			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT6	0.37385875	0.14153846	26	4	FALSE	SEPT6	SEPT6	120.8076923	0	26	0	0.7208655	FALSE	0	SEPT6	40304	0.05654622
790260	taxon:9606	2.5720813	3.38E-05	173490	1902	UFM1 specific ligase 1	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:1990592-&&-protein K69-linked ufmylation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0071569-&&-protein ufmylation-%%-GO:0032434-&&-regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0032880-&&-regulation of protein localization|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0071568-&&-UFM1 transferase activity	G:9606:UFL1				UFL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UFL1	0.3887902	0.04923077	26	4	FALSE	UFL1	UFL1	208.9615385	0	26	0	0.73798645	FALSE	0	UFL1	81312	0.07602569
790320	taxon:9606	2.53158973	3.44E-05	173327	1902	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	gene	biological_process-&-1&-GO:0046655-&&-folic acid metabolic process-%%-GO:0009257-&&-10-formyltetrahydrofolate biosynthetic process-%%-GO:0048702-&&-embryonic neurocranium morphogenesis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0001843-&&-neural tube closure-%%-GO:0015942-&&-formate metabolic process-%%-GO:0006760-&&-folic acid-containing compound metabolic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0009113-&&-purine nucleobase biosynthetic process-%%-GO:0048703-&&-embryonic viscerocranium morphogenesis|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004488-&&-methylenetetrahydrofolate dehydrogenase (NADP+) activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004329-&&-formate-tetrahydrofolate ligase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004477-&&-methenyltetrahydrofolate cyclohydrolase activity	G:9606:MTHFD1L			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways	MTHFD1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFD1L	0.39500871	0.10153846	26	4	FALSE	MTHFD1L	MTHFD1L	252.6923077	0	26	0	0.74473505	FALSE	0	MTHFD1L	72572	0.0839126
790380	taxon:9606	2.64896802	4.42E-05	173168	1902	calcium regulated heat stable protein 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0000177-&&-cytoplasmic exosome (RNase complex)-%%-GO:0000932-&&-P-body-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043186-&&-P granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:CARHSP1				CARHSP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARHSP1	0.3775055	0.09230769	26	4	FALSE	CARHSP1	CARHSP1	166.2692308	0	26	0	0.725172	FALSE	0	CARHSP1	81124	0.07252267
790418	taxon:9606	2.83693083	2.48E-05	173055	1902	MAF bZIP transcription factor F	gene	biological_process-&-1&-GO:0007567-&&-parturition-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045604-&&-regulation of epidermal cell differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:MAFF				MAFF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAFF	0.35249361	0.12681159	26	5	FALSE	MAFF	MAFF	79.20833333	0	25	0	0.69384486	FALSE	1	MAFF	28318	0.0655749
790458	taxon:9606	2.66566882	1.34E-05	172798	1902	zinc finger protein 451	gene	biological_process-&-1&-GO:2000616-&&-negative regulation of histone H3-K9 acetylation-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060633-&&-negative regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0061665-&&-SUMO ligase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding	G:9606:ZNF451				ZNF451	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF451	0.37514037	0.16304348	26	4	FALSE	ZNF451	ZNF451	163.4166667	0	25	0	0.72238853	FALSE	1	ZNF451	29178	0.07458143
790541	taxon:9606	2.49456436	2.88E-05	172542	1902	RAB guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:1900235-&&-negative regulation of Kit signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0060368-&&-regulation of Fc receptor mediated stimulatory signaling pathway-%%-GO:0043305-&&-negative regulation of mast cell degranulation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048261-&&-negative regulation of receptor-mediated endocytosis-%%-GO:0006897-&&-endocytosis-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0002686-&&-negative regulation of leukocyte migration-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006612-&&-protein targeting to membrane-%%-GO:1900165-&&-negative regulation of interleukin-6 secretion|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0055037-&&-recycling endosome|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:RABGEF1				RABGEF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABGEF1	0.4008716	0.18115942	26	4	FALSE	RABGEF1	RABGEF1	256.4583333	0	25	0	0.75090594	FALSE	1	RABGEF1	59906	0.07939765
790590	taxon:9606	2.79092485	4.22E-05	172054	1902	AF4/FMR2 family member 4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035327-&&-transcriptionally active chromatin|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:AFF4				AFF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AFF4	0.35830417	0.19076923	26	5	FALSE	AFF4	AFF4	79.73076923	0	26	0	0.70151253	FALSE	0	AFF4	42844	0.05496784
790656	taxon:9606	2.69591933	1.94E-05	171614	1902	membrane associated ring-CH-type finger 5	gene	biological_process-&-1&-GO:0090344-&&-negative regulation of cell aging-%%-GO:0070585-&&-protein localization to mitochondrion-%%-GO:0090140-&&-regulation of mitochondrial fission-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:MARCH5				5-Mar	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCH5	0.37093098	0.12318841	26	4	FALSE	5-Mar	5-Mar	151.2083333	0	25	0	0.71734678	FALSE	1	5-Mar	32248	0.07647679
790665	taxon:9606	2.67858831	3.28E-05	171550	1902	acyl-CoA dehydrogenase family member 9	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003995-&&-acyl-CoA dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:ACAD9				ACAD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAD9	0.37333098	0.19076923	26	4	FALSE	ACAD9	ACAD9	122.6153846	0	26	0	0.72023528	FALSE	0	ACAD9	49480	0.05793804
790677	taxon:9606	2.73010871	2.63E-05	171507	1902	charged multivesicular body protein 4A	gene	biological_process-&-1&-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0006900-&&-membrane budding-%%-GO:0097320-&&-plasma membrane tubulation-%%-GO:0016236-&&-macroautophagy-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0019058-&&-viral life cycle-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006997-&&-nucleus organization-%%-GO:0007034-&&-vacuolar transport-%%-GO:0051258-&&-protein polymerization-%%-GO:0006620-&&-posttranslational protein targeting to membrane-%%-GO:0016197-&&-endosomal transport-%%-GO:0010324-&&-membrane invagination-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030117-&&-membrane coat-%%-GO:0005634-&&-nucleus-%%-GO:0000815-&&-ESCRT III complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0030496-&&-midbody-%%-GO:0031902-&&-late endosome membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008289-&&-lipid binding-%%-GO:0042802-&&-identical protein binding	G:9606:CHMP4A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	CHMP4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHMP4A	0.36628578	0.13043478	26	4	FALSE	CHMP4A	CHMP4A	102.875	0	25	0	0.71164855	FALSE	1	CHMP4A	33968	0.05692521
790679	taxon:9606	2.69418623	4.04E-05	171490	1902	SSU72 homolog, RNA polymerase II CTD phosphatase	gene	biological_process-&-1&-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0070940-&&-dephosphorylation of RNA polymerase II C-terminal domain|cellular_component-&-1&-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008420-&&-CTD phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:SSU72			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	SSU72	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSU72	0.37116959	0.05230769	26	4	FALSE	SSU72	SSU72	118.5384615	0	26	0	0.71763563	FALSE	0	SSU72	49250	0.05822281
790695	taxon:9606	2.5407279	6.59E-05	171448	1902	non-SMC condensin II complex subunit H2	gene	biological_process-&-1&-GO:0030261-&&-chromosome condensation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NCAPH2				NCAPH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPH2	0.39358799	0.15942029	26	4	FALSE	NCAPH2	NCAPH2	205.25	0	25	0	0.74321202	FALSE	1	NCAPH2	84624	0.06974206
790903	taxon:9606	2.57617772	2.14E-05	170734	1902	zinc finger C3HC-type containing 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:ZC3HC1				ZC3HC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZC3HC1	0.38817198	0.08	26	4	FALSE	ZC3HC1	ZC3HC1	207	0	26	0	0.73730371	FALSE	0	ZC3HC1	51564	0.07587823
790904	taxon:9606	2.51646447	5.47E-05	170731	1902	vesicle trafficking 1	gene	biological_process-&-1&-GO:0036258-&&-multivesicular body assembly-%%-GO:0016197-&&-endosomal transport-%%-GO:0046755-&&-viral budding-%%-GO:1904903-&&-ESCRT III complex disassembly-%%-GO:0015031-&&-protein transport-%%-GO:0019058-&&-viral life cycle-%%-GO:0016236-&&-macroautophagy-%%-GO:0071985-&&-multivesicular body sorting pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:VTA1			KEGG-&-1&-hsa04144-&&-Endocytosis	VTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VTA1	0.39738292	0.08615385	26	4	FALSE	VTA1	VTA1	198.6538462	0	26	0	0.74725592	FALSE	0	VTA1	84580	0.06418961
790918	taxon:9606	2.60579801	2.09E-05	170703	1902	PCF11 cleavage and polyadenylation factor subunit	gene	biological_process-&-1&-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006378-&&-mRNA polyadenylation-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005849-&&-mRNA cleavage factor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0000993-&&-RNA polymerase II core binding	G:9606:PCF11			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	PCF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCF11	0.3837596	0.2	26	4	FALSE	PCF11	PCF11	198.3846154	0	26	0	0.732367	FALSE	0	PCF11	37460	0.07755483
790928	taxon:9606	2.63746652	3.51E-05	170686	1902	TATA-box binding protein associated factor 9b	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0050821-&&-protein stabilization-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TAF9B			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF9B	0.37915173	0.35144928	26	4	FALSE	TAF9B	TAF9B	153.375	0	25	0	0.72708891	FALSE	1	TAF9B	47846	0.06489129
790962	taxon:9606	2.68993225	3.98E-05	170580	1902	syntaxin 17	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0048278-&&-vesicle docking-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016240-&&-autophagosome docking-%%-GO:0007030-&&-Golgi organization-%%-GO:0006887-&&-exocytosis-%%-GO:0034497-&&-protein localization to pre-autophagosomal structure-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0097111-&&-endoplasmic reticulum-Golgi intermediate compartment organization-%%-GO:0006906-&&-vesicle fusion|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0030897-&&-HOPS complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005776-&&-autophagosome-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0030868-&&-smooth endoplasmic reticulum membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0044233-&&-ER-mitochondrion membrane contact site-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0000149-&&-SNARE binding	G:9606:STX17			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04140-&&-Autophagy - animal	STX17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX17	0.37175657	0.07384615	26	4	FALSE	STX17	STX17	123.3461539	0	26	0	0.71834462	FALSE	0	STX17	54234	0.06084676
791144	taxon:9606	2.52875374	3.03E-05	169894	1902	tetratricopeptide repeat domain 27	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TTC27				TTC27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC27	0.39545171	0.13230769	26	4	FALSE	TTC27	TTC27	224.3461539	0	26	0	0.74520771	FALSE	0	TTC27	66268	0.07422402
791247	taxon:9606	2.59902316	3.95E-05	169541	1902	CTP synthase 2	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0044210-&&-'de novo' CTP biosynthetic process-%%-GO:0006220-&&-pyrimidine nucleotide metabolic process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003883-&&-CTP synthase activity-%%-GO:0005515-&&-protein binding	G:9606:CTPS2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways	CTPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTPS2	0.38475994	0.14855072	26	4	FALSE	CTPS2	CTPS2	180.625	0	25	0	0.73349614	FALSE	1	CTPS2	58030	0.06940705
791299	taxon:9606	2.79202773	1.33E-05	169292	1902	calmodulin regulated spectrin associated protein family member 3	gene	biological_process-&-1&-GO:0045218-&&-zonula adherens maintenance-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0034453-&&-microtubule anchoring-%%-GO:0031175-&&-neuron projection development-%%-GO:0033043-&&-regulation of organelle organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule-%%-GO:0005915-&&-zonula adherens|molecular_function-&-1&-GO:0030507-&&-spectrin binding-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0005516-&&-calmodulin binding	G:9606:CAMSAP3				CAMSAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMSAP3	0.35816263	0.21538462	26	4	FALSE	CAMSAP3	CAMSAP3	217.3461539	0	26	0	0.70132871	FALSE	0	CAMSAP3	39778	0.14474359
791448	taxon:9606	2.79517882	4.47E-05	168595	1902	MIS12, kinetochore complex component	gene	biological_process-&-1&-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0051301-&&-cell division-%%-GO:0007059-&&-chromosome segregation-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0051382-&&-kinetochore assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000444-&&-MIS12/MIND type complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MIS12				MIS12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MIS12	0.35775886	0.13405797	26	4	FALSE	MIS12	MIS12	81.33333333	0	25	0	0.70080353	FALSE	1	MIS12	47400	0.05620088
791471	taxon:9606	2.64849535	6.49E-05	168497	1902	chromosome 12 open reading frame 10	gene	biological_process-&-1&-GO:0043473-&&-pigmentation-%%-GO:0035641-&&-locomotory exploration behavior|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:C12orf10				C12orf10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C12orf10	0.37757287	0.12	26	4	FALSE	C12orf10	C12orf10	135.5	0	26	0	0.72525077	FALSE	0	C12orf10	67858	0.05929347
791539	taxon:9606	2.74224043	7.23E-05	168190	1902	cysteine rich with EGF like domains 2	gene	cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:CRELD2				CRELD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRELD2	0.36466533	0.04307692	26	4	FALSE	CRELD2	CRELD2	111.9230769	0	26	0	0.7096266	FALSE	0	CRELD2	76536	0.06620504
791635	taxon:9606	2.88687569	8.67E-06	167715	1902	ATPase family, AAA domain containing 5	gene	biological_process-&-1&-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:ATAD5				ATAD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD5	0.34639524	0.27076923	26	4	FALSE	ATAD5	ATAD5	214.5769231	0	26	0	0.68552072	FALSE	0	ATAD5	26476	0.20331754
791712	taxon:9606	2.90751536	5.06E-05	167229	1902	sperm acrosome associated 1	gene	biological_process-&-1&-GO:0001675-&&-acrosome assembly|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0002080-&&-acrosomal membrane	G:9606:SPACA1				SPACA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPACA1	0.34393627	0.01230769	26	5	FALSE	SPACA1	SPACA1	35.38461538	0	26	0	0.68208077	FALSE	0	SPACA1	39340	0.0461436
791938	taxon:9606	2.74822751	6.13E-05	182843	1902	alkaline phosphatase, placental	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0031225-&&-anchored component of membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004035-&&-alkaline phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ALPP	ALPP	TRUE	KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	ALPP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALPP	0.36387089	0.15384615	26	5	FALSE	ALPP	ALPP	129.9615385	0	26	0	0.70862875	FALSE	0	ALPP	83230	0.07692308
791950	taxon:9606	2.72034032	8.23E-06	166428	1902	stonin 2	gene	biological_process-&-1&-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0030100-&&-regulation of endocytosis|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0043005-&&-neuron projection-%%-GO:0030054-&&-cell junction-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:STON2				STON2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STON2	0.36760107	0.42391304	26	4	FALSE	STON2	STON2	182.875	0	25	0	0.71327661	FALSE	1	STON2	19536	0.09938859
792079	taxon:9606	2.59146053	3.33E-05	166271	1902	arrestin domain containing 1	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ARRDC1				ARRDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRDC1	0.38588278	0.10153846	26	4	FALSE	ARRDC1	ARRDC1	159.2307692	0	26	0	0.73475658	FALSE	0	ARRDC1	58846	0.06058608
792106	taxon:9606	2.70363951	1.30E-04	182603	1902	collagen type IV alpha 1 chain	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0007420-&&-brain development-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0071711-&&-basement membrane organization-%%-GO:0061304-&&-retinal blood vessel morphogenesis-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0061333-&&-renal tubule morphogenesis-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0048514-&&-blood vessel morphogenesis|cellular_component-&-1&-GO:0005587-&&-collagen type IV trimer-%%-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding-%%-GO:0030023-&&-extracellular matrix constituent conferring elasticity-%%-GO:0048407-&&-platelet-derived growth factor binding	G:9606:COL4A1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	COL4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A1	0.36987179	0.11594203	26	4	FALSE	COL4A1	COL4A1	107.875	0	25	0	0.71606008	FALSE	1	COL4A1	109262	0.05547693
792114	taxon:9606	2.7893493	6.55E-05	182590	1902	collagen type VIII alpha 1 chain	gene	biological_process-&-1&-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0007155-&&-cell adhesion-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005591-&&-collagen type VIII trimer|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COL8A1	COL8A1	TRUE		COL8A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL8A1	0.35850655	0.16	26	4	FALSE	COL8A1	COL8A1	94.34615385	0	26	0	0.70177512	FALSE	0	COL8A1	69812	0.06366856
792122	taxon:9606	2.72490941	3.89E-05	182564	1902	cytochrome c oxidase subunit 5B	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0006123-&&-mitochondrial electron transport, cytochrome c to oxygen-%%-GO:0042776-&&-mitochondrial ATP synthesis coupled proton transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005751-&&-mitochondrial respiratory chain complex IV-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004129-&&-cytochrome-c oxidase activity-%%-GO:0005515-&&-protein binding	G:9606:COX5B			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease	COX5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COX5B	0.36698468	0.06153846	26	4	FALSE	COX5B	COX5B	101.2307692	0	26	0	0.7125151	FALSE	0	COX5B	46960	0.05572782
792240	taxon:9606	2.78714353	2.22E-05	165983	1902	nicotinate phosphoribosyltransferase	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019358-&&-nicotinate nucleotide salvage-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0004514-&&-nicotinate-nucleotide diphosphorylase (carboxylating) activity-%%-GO:0004516-&&-nicotinate phosphoribosyltransferase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding	G:9606:NAPRT			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	NAPRT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAPRT	0.35879028	0.04307692	26	4	FALSE	NAPRT	NAPRT	84.88461538	0	26	0	0.70214274	FALSE	0	NAPRT	28328	0.05898152
792504	taxon:9606	2.8008508	1.81E-05	165515	1902	FLYWCH family member 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:FLYWCH2				FLYWCH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLYWCH2	0.35703437	0.14153846	26	4	FALSE	FLYWCH2	FLYWCH2	228.8846154	0	26	0	0.6998582	FALSE	0	FLYWCH2	43738	0.16380642
792781	taxon:9606	2.59729006	5.18E-05	181376	1902	ephrin B1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0031295-&&-T cell costimulation-%%-GO:0007411-&&-axon guidance-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0007155-&&-cell adhesion-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001755-&&-neural crest cell migration|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0046875-&&-ephrin receptor binding-%%-GO:0005515-&&-protein binding	G:9606:EFNB1			KEGG-&-1&-hsa04360-&&-Axon guidance	EFNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFNB1	0.38501668	0.07971014	26	4	FALSE	EFNB1	EFNB1	178.5	0	25	0	0.73378499	FALSE	1	EFNB1	75636	0.06873233
792860	taxon:9606	2.58941232	2.87E-05	181258	1902	endoplasmic reticulum to nucleus signaling 1	gene	biological_process-&-1&-GO:0070055-&&-mRNA endonucleolytic cleavage involved in unfolded protein response-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:1900103-&&-positive regulation of endoplasmic reticulum unfolded protein response-%%-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:0070054-&&-mRNA splicing, via endonucleolytic cleavage and ligation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006379-&&-mRNA cleavage-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:1990579-&&-peptidyl-serine trans-autophosphorylation-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033120-&&-positive regulation of RNA splicing-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:1901142-&&-insulin metabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:1990630-&&-IRE1-RACK1-PP2A complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:1990332-&&-Ire1 complex-%%-GO:1990597-&&-AIP1-IRE1 complex-%%-GO:1990604-&&-IRE1-TRAF2-ASK1 complex-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0043531-&&-ADP binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0019899-&&-enzyme binding	G:9606:ERN1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	ERN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERN1	0.38618801	0.20289855	26	4	FALSE	ERN1	ERN1	199.5833333	0	25	0	0.73509795	FALSE	1	ERN1	45772	0.07562547
792886	taxon:9606	2.84102726	7.70E-05	181213	1902	coagulation factor II thrombin receptor	gene	biological_process-&-1&-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0032651-&&-regulation of interleukin-1 beta production-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:2000484-&&-positive regulation of interleukin-8 secretion-%%-GO:0003105-&&-negative regulation of glomerular filtration-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0060155-&&-platelet dense granule organization-%%-GO:0030168-&&-platelet activation-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0007529-&&-establishment of synaptic specificity at neuromuscular junction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0099553-&&-trans-synaptic signaling by endocannabinoid, modulating synaptic transmission-%%-GO:0007596-&&-blood coagulation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0070493-&&-thrombin-activated receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:1900134-&&-negative regulation of renin secretion into blood stream-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0009611-&&-response to wounding-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031094-&&-platelet dense tubular network-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005769-&&-early endosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005770-&&-late endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0015057-&&-thrombin-activated receptor activity-%%-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0001965-&&-G-protein alpha-subunit binding	G:9606:F2R			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04610-&&-Complement and coagulation cascades	F2R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F2R	0.35198536	0.03384615	26	4	FALSE	F2R	F2R	57.76923077	0	26	0	0.69316212	FALSE	0	F2R	61144	0.05342279
793096	taxon:9606	2.66976524	2.11E-05	180739	1902	GATA binding protein 3	gene	biological_process-&-1&-GO:0045064-&&-T-helper 2 cell differentiation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010975-&&-regulation of neuron projection development-%%-GO:0051569-&&-regulation of histone H3-K4 methylation-%%-GO:0071442-&&-positive regulation of histone H3-K14 acetylation-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0007411-&&-axon guidance-%%-GO:0043583-&&-ear development-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0061085-&&-regulation of histone H3-K27 methylation-%%-GO:2000667-&&-positive regulation of interleukin-13 secretion-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072178-&&-nephric duct morphogenesis-%%-GO:0001806-&&-type IV hypersensitivity-%%-GO:0048589-&&-developmental growth-%%-GO:0008584-&&-male gonad development-%%-GO:0048538-&&-thymus development-%%-GO:0071599-&&-otic vesicle development-%%-GO:0007165-&&-signal transduction-%%-GO:0035898-&&-parathyroid hormone secretion-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0060017-&&-parathyroid gland development-%%-GO:0061290-&&-canonical Wnt signaling pathway involved in metanephric kidney development-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0002572-&&-pro-T cell differentiation-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:0031929-&&-TOR signaling-%%-GO:0042035-&&-regulation of cytokine biosynthetic process-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0003281-&&-ventricular septum development-%%-GO:0060065-&&-uterus development-%%-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0043370-&&-regulation of CD4-positive, alpha-beta T cell differentiation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0001822-&&-kidney development-%%-GO:0001709-&&-cell fate determination-%%-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:2000703-&&-negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation-%%-GO:0001764-&&-neuron migration-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0072179-&&-nephric duct formation-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032703-&&-negative regulation of interleukin-2 production-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0072182-&&-regulation of nephron tubule epithelial cell differentiation-%%-GO:2000611-&&-positive regulation of thyroid hormone generation-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0060676-&&-ureteric bud formation-%%-GO:2000607-&&-negative regulation of cell proliferation involved in mesonephros development-%%-GO:2000664-&&-positive regulation of interleukin-5 secretion-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0006952-&&-defense response-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0072676-&&-lymphocyte migration-%%-GO:0006959-&&-humoral immune response-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0045471-&&-response to ethanol-%%-GO:0042493-&&-response to drug-%%-GO:0072643-&&-interferon-gamma secretion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0090102-&&-cochlea development-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0035799-&&-ureter maturation-%%-GO:0048469-&&-cell maturation-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0045061-&&-thymic T cell selection-%%-GO:0042421-&&-norepinephrine biosynthetic process-%%-GO:0072107-&&-positive regulation of ureteric bud formation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007596-&&-blood coagulation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000553-&&-positive regulation of T-helper 2 cell cytokine production-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:2000734-&&-negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation-%%-GO:0003180-&&-aortic valve morphogenesis-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0060037-&&-pharyngeal system development-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0043627-&&-response to estrogen-%%-GO:0009791-&&-post-embryonic development-%%-GO:0009615-&&-response to virus-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation-%%-GO:1901536-&&-negative regulation of DNA demethylation-%%-GO:2000683-&&-regulation of cellular response to X-ray-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0060374-&&-mast cell differentiation-%%-GO:0001823-&&-mesonephros development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001071-&&-nucleic acid binding transcription factor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0005134-&&-interleukin-2 receptor binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding	G:9606:GATA3			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04658-&&-Th1 and Th2 cell differentiation	GATA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATA3	0.37456477	0.11384615	26	5	FALSE	GATA3	GATA3	164.5384615	0	26	0	0.72170579	FALSE	0	GATA3	42158	0.07542412
793176	taxon:9606	2.58563101	3.21E-05	180587	1902	golgin A3	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0090498-&&-extrinsic component of Golgi membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:GOLGA3				GOLGA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLGA3	0.38675279	0.07608696	26	4	FALSE	GOLGA3	GOLGA3	202.5833333	0	25	0	0.73572817	FALSE	1	GOLGA3	53946	0.0756825
793200	taxon:9606	2.57302663	3.78E-05	180543	1902	ArfGAP with FG repeats 1	gene	biological_process-&-1&-GO:0045109-&&-intermediate filament organization-%%-GO:0061024-&&-membrane organization-%%-GO:0001675-&&-acrosome assembly-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007289-&&-spermatid nucleus differentiation|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGFG1			KEGG-&-1&-hsa05164-&&-Influenza A	AGFG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGFG1	0.38864736	0.19927536	26	4	FALSE	AGFG1	AGFG1	192.375	0	25	0	0.7378289	FALSE	1	AGFG1	57402	0.06967089
793337	taxon:9606	2.76618875	6.45E-05	180291	1902	major histocompatibility complex, class II, DR alpha	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0006955-&&-immune response-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0050890-&&-cognition-%%-GO:0002503-&&-peptide antigen assembly with MHC class II protein complex-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0002504-&&-antigen processing and presentation of peptide or polysaccharide antigen via MHC class II-%%-GO:0002506-&&-polysaccharide assembly with MHC class II protein complex-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042613-&&-MHC class II protein complex-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005764-&&-lysosome-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane|molecular_function-&-1&-GO:0032395-&&-MHC class II receptor activity-%%-GO:0023026-&&-MHC class II protein complex binding-%%-GO:0042605-&&-peptide antigen binding	G:9606:HLA-DRA			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05310-&&-Asthma-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05323-&&-Rheumatoid arthritis	HLA-DRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-DRA	0.36150823	0.05072464	26	4	FALSE	HLA-DRA	HLA-DRA	90	0	25	0	0.70563521	FALSE	1	HLA-DRA	54192	0.05784345
793344	taxon:9606	2.67291634	3.25E-05	180266	1902	high mobility group nucleosome binding domain 1	gene	biological_process-&-1&-GO:0010225-&&-response to UV-C-%%-GO:0006325-&&-chromatin organization-%%-GO:0040034-&&-regulation of development, heterochronic-%%-GO:0000720-&&-pyrimidine dimer repair by nucleotide-excision repair-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0048597-&&-post-embryonic camera-type eye morphogenesis-%%-GO:1901666-&&-positive regulation of NAD+ ADP-ribosyltransferase activity-%%-GO:0010224-&&-response to UV-B-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0050678-&&-regulation of epithelial cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000785-&&-chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0031492-&&-nucleosomal DNA binding	G:9606:HMGN1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	HMGN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGN1	0.37412319	0.09782609	26	4	FALSE	HMGN1	HMGN1	140.7083333	0	25	0	0.72118061	FALSE	1	HMGN1	45666	0.06615221
787028	taxon:9606	2.86781156	1.63E-05	163826	1902	lactate dehydrogenase A like 6A	gene	biological_process-&-1&-GO:0019752-&&-carboxylic acid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004459-&&-L-lactate dehydrogenase activity	G:9606:LDHAL6A			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00620-&&-Pyruvate metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis	LDHAL6A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHAL6A	0.34869795	0.13666667	25	4	FALSE	LDHAL6A	LDHAL6A	72.2	0	25	0	0.68869807	FALSE	0	LDHAL6A	22890	0.07226453
787052	taxon:9606	2.47030093	3.71E-05	180163	1902	isocitrate dehydrogenase 3 (NAD(+)) beta	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006102-&&-isocitrate metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0004449-&&-isocitrate dehydrogenase (NAD+) activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:IDH3B			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism	IDH3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDH3B	0.40480898	0.16	25	4	FALSE	IDH3B	IDH3B	265.88	0	25	0	0.75494985	FALSE	0	IDH3B	84354	0.07845336
787156	taxon:9606	2.72490941	6.10E-05	179967	1902	lysyl oxidase	gene	biological_process-&-1&-GO:0035904-&&-aorta development-%%-GO:0007507-&&-heart development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0048251-&&-elastic fiber assembly-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0030324-&&-lung development-%%-GO:0042060-&&-wound healing-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0042493-&&-response to drug-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0048514-&&-blood vessel morphogenesis|cellular_component-&-1&-GO:0005581-&&-collagen trimer-%%-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005507-&&-copper ion binding-%%-GO:0004720-&&-protein-lysine 6-oxidase activity-%%-GO:0005515-&&-protein binding	G:9606:LOX	LOX	TRUE		LOX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOX	0.36698468	0.07509881	25	4	FALSE	LOX	LOX	114.2173913	0	24	0	0.7125151	FALSE	1	LOX	62558	0.06251043
787180	taxon:9606	2.51788246	2.41E-05	179915	1902	myristoylated alanine rich protein kinase C substrate	gene	biological_process-&-1&-GO:0050796-&&-regulation of insulin secretion|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005813-&&-centrosome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0042585-&&-germinal vesicle|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MARCKS			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis	MARCKS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCKS	0.39715913	0.12333333	25	4	FALSE	MARCKS	MARCKS	253.88	0	25	0	0.74701959	FALSE	0	MARCKS	61936	0.08267188
787192	taxon:9606	2.79643926	1.22E-05	179903	1902	MAF bZIP transcription factor	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048468-&&-cell development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032330-&&-regulation of chondrocyte differentiation-%%-GO:0001816-&&-cytokine production-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0048839-&&-inner ear development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:MAF			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04658-&&-Th1 and Th2 cell differentiation	MAF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAF	0.35759761	0.27272727	25	4	FALSE	MAF	MAF	131.1304348	0	24	0	0.70059346	FALSE	1	MAF	18208	0.09071762
787204	taxon:9606	2.61288798	4.81E-05	179871	1902	microtubule associated protein 1A	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:MAP1A				MAP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP1A	0.38271828	0.13666667	25	4	FALSE	MAP1A	MAP1A	158.64	0	25	0	0.73118534	FALSE	0	MAP1A	62970	0.06360209
787217	taxon:9606	2.64676225	3.01E-05	179850	1902	muscleblind like splicing regulator 1	gene	biological_process-&-1&-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0007399-&&-nervous system development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0006397-&&-mRNA processing-%%-GO:0043484-&&-regulation of RNA splicing-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus-%%-GO:0010494-&&-cytoplasmic stress granule|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0001069-&&-regulatory region RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MBNL1				MBNL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBNL1	0.37782011	0.25	25	4	FALSE	MBNL1	MBNL1	189.12	0	25	0	0.72553963	FALSE	0	MBNL1	41454	0.08273205
787276	taxon:9606	2.69954309	1.15E-04	179756	1902	potassium voltage-gated channel subfamily D member 3	gene	biological_process-&-1&-GO:0097623-&&-potassium ion export across plasma membrane-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:0061337-&&-cardiac conduction-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071435-&&-potassium ion export-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:0086009-&&-membrane repolarization-%%-GO:0099625-&&-ventricular cardiac muscle cell membrane repolarization-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0005515-&&-protein binding-%%-GO:0086008-&&-voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization-%%-GO:0005250-&&-A-type (transient outward) potassium channel activity-%%-GO:0044325-&&-ion channel binding	G:9606:KCND3	KCND3	TRUE		KCND3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCND3	0.37043306	0.04347826	25	4	FALSE	KCND3	KCND3	152.3913044	0	24	0	0.71674282	FALSE	1	KCND3	210070	0.0777224
787329	taxon:9606	2.65779108	2.70E-05	163273	1902	STT3B, catalytic subunit of the oligosaccharyltransferase complex	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0006516-&&-glycoprotein catabolic process-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0043686-&&-co-translational protein modification-%%-GO:0043687-&&-post-translational protein modification-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity	G:9606:STT3B			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	STT3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STT3B	0.3762523	0.17333333	25	4	FALSE	STT3B	STT3B	161.24	0	25	0	0.72370149	FALSE	0	STT3B	51692	0.07142224
787476	taxon:9606	2.51016228	2.84E-05	179357	1902	melanogenesis associated transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:2001141-&&-regulation of RNA biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:2000144-&&-positive regulation of DNA-templated transcription, initiation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016925-&&-protein sumoylation-%%-GO:0097531-&&-mast cell migration|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:MITF			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05218-&&-Melanoma-%%-hsa04916-&&-Melanogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04380-&&-Osteoclast differentiation	MITF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MITF	0.39838062	0.18	25	4	FALSE	MITF	MITF	229.24	0	25	0	0.74830629	FALSE	0	MITF	58800	0.07339097
787493	taxon:9606	2.56247046	1.66E-05	179341	1902	forkhead box O4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0070317-&&-negative regulation of G0 to G1 transition-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1990785-&&-response to water-immersion restraint stress-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007568-&&-aging-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0051151-&&-negative regulation of smooth muscle cell differentiation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXO4			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	FOXO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO4	0.3902484	0.256917	25	4	FALSE	FOXO4	FOXO4	237.0434783	0	24	0	0.73958826	FALSE	1	FOXO4	31664	0.08398299
787505	taxon:9606	2.87521664	3.05E-04	179326	1902	matrix metallopeptidase 14	gene	biological_process-&-1&-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0048870-&&-cell motility-%%-GO:0043627-&&-response to estrogen-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0031638-&&-zymogen activation-%%-GO:1990834-&&-response to odorant-%%-GO:0030324-&&-lung development-%%-GO:0035988-&&-chondrocyte proliferation-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0048771-&&-tissue remodeling-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0016485-&&-protein processing-%%-GO:0009725-&&-response to hormone-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:1905523-&&-positive regulation of macrophage migration-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006508-&&-proteolysis-%%-GO:0001525-&&-angiogenesis-%%-GO:0010952-&&-positive regulation of peptidase activity-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0097094-&&-craniofacial suture morphogenesis-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0008584-&&-male gonad development-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0001958-&&-endochondral ossification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0042470-&&-melanosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0044354-&&-macropinosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016504-&&-peptidase activator activity-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:MMP14			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04912-&&-GnRH signaling pathway	MMP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP14	0.34779988	0.05666667	25	4	FALSE	MMP14	MMP14	46.52	0	25	0	0.68746389	FALSE	0	MMP14	320606	0.05037037
787519	taxon:9606	2.90326138	7.84E-05	162901	1902	lipase H	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0044241-&&-lipid digestion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0004620-&&-phospholipase activity-%%-GO:0008201-&&-heparin binding	G:9606:LIPH				LIPH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIPH	0.34444022	0.00666667	25	4	FALSE	LIPH	LIPH	41.56	0	25	0	0.68278977	FALSE	0	LIPH	98288	0.0500861
787529	taxon:9606	2.71561368	5.29E-04	179240	1902	opioid receptor mu 1	gene	biological_process-&-1&-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0061358-&&-negative regulation of Wnt protein secretion-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0044849-&&-estrous cycle-%%-GO:0007600-&&-sensory perception-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0031635-&&-adenylate cyclase-inhibiting opioid receptor signaling pathway-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0009314-&&-response to radiation-%%-GO:0019233-&&-sensory perception of pain-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0042060-&&-wound healing-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0002438-&&-acute inflammatory response to antigenic stimulus-%%-GO:0032100-&&-positive regulation of appetite-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0032094-&&-response to food-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0042220-&&-response to cocaine-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0033554-&&-cellular response to stress-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0038003-&&-opioid receptor signaling pathway-%%-GO:0070848-&&-response to growth factor-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0071315-&&-cellular response to morphine-%%-GO:0007626-&&-locomotory behavior-%%-GO:0042755-&&-eating behavior-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0030425-&&-dendrite-%%-GO:0098794-&&-postsynapse-%%-GO:0042383-&&-sarcolemma-%%-GO:0045121-&&-membrane raft-%%-GO:0005768-&&-endosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0032590-&&-dendrite membrane|molecular_function-&-1&-GO:0042923-&&-neuropeptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0038047-&&-morphine receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0004979-&&-beta-endorphin receptor activity-%%-GO:0031005-&&-filamin binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005245-&&-voltage-gated calcium channel activity	G:9606:OPRM1	OPRM1	TRUE	KEGG-&-1&-hsa05032-&&-Morphine addiction-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	OPRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPRM1	0.36824089	0.08666667	25	4	FALSE	OPRM1	OPRM1	105.96	0	25	0	0.71406439	FALSE	0	OPRM1	580868	0.05675966
787661	taxon:9606	2.73436269	2.89E-05	178997	1902	nuclear receptor subfamily 4 group A member 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0042551-&&-neuron maturation-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0042053-&&-regulation of dopamine metabolic process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0001975-&&-response to amphetamine-%%-GO:0021952-&&-central nervous system projection neuron axonogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009791-&&-post-embryonic development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0071376-&&-cellular response to corticotropin-releasing hormone stimulus-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0021986-&&-habenula development-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0001764-&&-neuron migration-%%-GO:0043576-&&-regulation of respiratory gaseous exchange-%%-GO:0051866-&&-general adaptation syndrome-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046965-&&-retinoid X receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:NR4A2			KEGG-&-1&-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	NR4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR4A2	0.36571593	0.11	25	4	FALSE	NR4A2	NR4A2	120.72	0	25	0	0.71093955	FALSE	0	NR4A2	36302	0.06803844
787676	taxon:9606	2.5985505	3.78E-05	178970	1902	phosphatidylinositol 3-kinase catalytic subunit type 3	gene	biological_process-&-1&-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0016236-&&-macroautophagy-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0006914-&&-autophagy-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0034497-&&-protein localization to pre-autophagosomal structure-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0006497-&&-protein lipidation-%%-GO:0007032-&&-endosome organization-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016485-&&-protein processing-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0000910-&&-cytokinesis-%%-GO:0043201-&&-response to leucine|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0044754-&&-autolysosome-%%-GO:0005770-&&-late endosome-%%-GO:0005930-&&-axoneme-%%-GO:0005829-&&-cytosol-%%-GO:0035032-&&-phosphatidylinositol 3-kinase complex, class III-%%-GO:0016020-&&-membrane-%%-GO:0030496-&&-midbody|molecular_function-&-1&-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:PIK3C3			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04136-&&-Autophagy - other	PIK3C3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3C3	0.38482993	0.16333333	25	4	FALSE	PIK3C3	PIK3C3	195.8	0	25	0	0.73357492	FALSE	0	PIK3C3	56194	0.07558131
787708	taxon:9606	2.80116591	3.84E-05	162521	1902	proprotein convertase subtilisin/kexin type 9	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0022008-&&-neurogenesis-%%-GO:0001920-&&-negative regulation of receptor recycling-%%-GO:0016540-&&-protein autoprocessing-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0010989-&&-negative regulation of low-density lipoprotein particle clearance-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0001889-&&-liver development-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0001822-&&-kidney development-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:1905598-&&-negative regulation of low-density lipoprotein receptor activity-%%-GO:0030182-&&-neuron differentiation-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007041-&&-lysosomal transport-%%-GO:0032802-&&-low-density lipoprotein particle receptor catabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:1905596-&&-negative regulation of low-density lipoprotein particle receptor binding-%%-GO:1905601-&&-negative regulation of receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0032805-&&-positive regulation of low-density lipoprotein particle receptor catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005764-&&-lysosome-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:1990667-&&-PCSK9-AnxA2 complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005770-&&-late endosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:1990666-&&-PCSK9-LDLR complex|molecular_function-&-1&-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0030547-&&-receptor inhibitor activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0034189-&&-very-low-density lipoprotein particle binding-%%-GO:0070326-&&-very-low-density lipoprotein particle receptor binding-%%-GO:0034190-&&-apolipoprotein receptor binding-%%-GO:0043621-&&-protein self-association-%%-GO:0019871-&&-sodium channel inhibitor activity	G:9606:PCSK9			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	PCSK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCSK9	0.35699421	0.03952569	25	4	FALSE	PCSK9	PCSK9	88.34782609	0	24	0	0.69980568	FALSE	1	PCSK9	37212	0.06563983
787803	taxon:9606	2.61477864	3.08E-05	178764	1902	protein kinase AMP-activated non-catalytic subunit gamma 1	gene	biological_process-&-1&-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0016236-&&-macroautophagy-%%-GO:0006110-&&-regulation of glycolytic process-%%-GO:0007165-&&-signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:1902593-&&-single-organism nuclear import-%%-GO:0045860-&&-positive regulation of protein kinase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0031588-&&-nucleotide-activated protein kinase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004691-&&-cAMP-dependent protein kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004679-&&-AMP-activated protein kinase activity-%%-GO:0016208-&&-AMP binding-%%-GO:0043531-&&-ADP binding	G:9606:PRKAG1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04530-&&-Tight junction-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04710-&&-Circadian rhythm-%%-hsa04921-&&-Oxytocin signaling pathway	PRKAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAG1	0.38244155	0.15333333	25	4	FALSE	PRKAG1	PRKAG1	160.36	0	25	0	0.73087023	FALSE	0	PRKAG1	50406	0.06442122
787826	taxon:9606	2.83062864	1.63E-05	162357	1902	BEN domain containing 7	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BEND7				BEND7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BEND7	0.35327841	0.05533597	25	5	FALSE	BEND7	BEND7	77.69565217	0	24	0	0.69489523	FALSE	1	BEND7	21346	0.06218159
787841	taxon:9606	2.72995116	2.48E-05	178728	1902	mitogen-activated protein kinase kinase 6	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0032308-&&-positive regulation of prostaglandin secretion-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0022602-&&-ovulation cycle process-%%-GO:0006975-&&-DNA damage induced protein phosphorylation-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0035897-&&-proteolysis in other organism-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0072709-&&-cellular response to sorbitol-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042493-&&-response to drug-%%-GO:0002931-&&-response to ischemia|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:MAP2K6			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	MAP2K6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K6	0.36630692	0.16205534	25	4	FALSE	MAP2K6	MAP2K6	119.4782609	0	24	0	0.71167481	FALSE	1	MAP2K6	32518	0.06696091
787917	taxon:9606	2.50638097	6.72E-05	178612	1902	prostaglandin-endoperoxide synthase 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0070542-&&-response to fatty acid-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:0030282-&&-bone mineralization-%%-GO:0030728-&&-ovulation-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0031622-&&-positive regulation of fever generation-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0046697-&&-decidualization-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0090336-&&-positive regulation of brown fat cell differentiation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0045986-&&-negative regulation of smooth muscle contraction-%%-GO:0006954-&&-inflammatory response-%%-GO:0007566-&&-embryo implantation-%%-GO:0042493-&&-response to drug-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0007612-&&-learning-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0090271-&&-positive regulation of fibroblast growth factor production-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033280-&&-response to vitamin D-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0006693-&&-prostaglandin metabolic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0090050-&&-positive regulation of cell migration involved in sprouting angiogenesis-%%-GO:0007568-&&-aging-%%-GO:0007613-&&-memory-%%-GO:0032227-&&-negative regulation of synaptic transmission, dopaminergic-%%-GO:0032355-&&-response to estradiol-%%-GO:0031394-&&-positive regulation of prostaglandin biosynthetic process-%%-GO:0010042-&&-response to manganese ion-%%-GO:0071636-&&-positive regulation of transforming growth factor beta production-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0042633-&&-hair cycle-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0035633-&&-maintenance of permeability of blood-brain barrier-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0090362-&&-positive regulation of platelet-derived growth factor production-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0009750-&&-response to fructose-%%-GO:0010226-&&-response to lithium ion-%%-GO:0034605-&&-cellular response to heat|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0005901-&&-caveola-%%-GO:0043005-&&-neuron projection-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0031090-&&-organelle membrane|molecular_function-&-1&-GO:0050473-&&-arachidonate 15-lipoxygenase activity-%%-GO:0004601-&&-peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004666-&&-prostaglandin-endoperoxide synthase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0008289-&&-lipid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0020037-&&-heme binding	G:9606:PTGS2	PTGS2	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05140-&&-Leishmaniasis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05200-&&-Pathways in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05204-&&-Chemical carcinogenesis	PTGS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGS2	0.39898164	0.22134387	25	4	FALSE	PTGS2	PTGS2	253.6956522	0	24	0	0.74893651	FALSE	1	PTGS2	72138	0.0809356
787983	taxon:9606	2.7527966	1.85E-05	178458	1902	phosphodiesterase 3A	gene	biological_process-&-1&-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0043117-&&-positive regulation of vascular permeability-%%-GO:0016101-&&-diterpenoid metabolic process-%%-GO:0019934-&&-cGMP-mediated signaling-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006198-&&-cAMP catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0051591-&&-response to cAMP-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0060282-&&-positive regulation of oocyte development-%%-GO:0040020-&&-regulation of meiotic nuclear division-%%-GO:0042493-&&-response to drug-%%-GO:0001556-&&-oocyte maturation-%%-GO:0071321-&&-cellular response to cGMP|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004119-&&-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity-%%-GO:0030552-&&-cAMP binding-%%-GO:0004115-&&-3',5'-cyclic-AMP phosphodiesterase activity-%%-GO:0047555-&&-3',5'-cyclic-GMP phosphodiesterase activity	G:9606:PDE3A	PDE3A	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa00230-&&-Purine metabolism-%%-hsa04022-&&-cGMP-PKG signaling pathway	PDE3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE3A	0.36326694	0.13438735	25	4	FALSE	PDE3A	PDE3A	115.6521739	0	24	0	0.70786723	FALSE	1	PDE3A	24678	0.0688449
788141	taxon:9606	2.52371199	2.30E-05	178171	1902	aldehyde dehydrogenase 18 family member A1	gene	biological_process-&-1&-GO:0055129-&&-L-proline biosynthetic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0006592-&&-ornithine biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019240-&&-citrulline biosynthetic process-%%-GO:0006536-&&-glutamate metabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006561-&&-proline biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004349-&&-glutamate 5-kinase activity-%%-GO:0004350-&&-glutamate-5-semialdehyde dehydrogenase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0017084-&&-delta1-pyrroline-5-carboxylate synthetase activity-%%-GO:0003723-&&-RNA binding	G:9606:ALDH18A1			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	ALDH18A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH18A1	0.39624173	0.17333333	25	4	FALSE	ALDH18A1	ALDH18A1	289.04	0	25	0	0.746048	FALSE	0	ALDH18A1	60358	0.09437439
788160	taxon:9606	2.68047897	2.78E-05	178144	1902	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)	gene	biological_process-&-1&-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0045453-&&-bone resorption-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0030168-&&-platelet activation-%%-GO:0060263-&&-regulation of respiratory burst-%%-GO:0007165-&&-signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0010592-&&-positive regulation of lamellipodium assembly-%%-GO:0006935-&&-chemotaxis-%%-GO:0007015-&&-actin filament organization-%%-GO:1902622-&&-regulation of neutrophil migration-%%-GO:0030031-&&-cell projection assembly-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0060753-&&-regulation of mast cell chemotaxis-%%-GO:0071593-&&-lymphocyte aggregation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010810-&&-regulation of cell-substrate adhesion-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010310-&&-regulation of hydrogen peroxide metabolic process|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0019887-&&-protein kinase regulator activity-%%-GO:0005525-&&-GTP binding	G:9606:RAC2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04360-&&-Axon guidance-%%-hsa05416-&&-Viral myocarditis-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04520-&&-Adherens junction	RAC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAC2	0.37306765	0.08695652	25	5	FALSE	RAC2	RAC2	172.6086957	0	24	0	0.71992017	FALSE	1	RAC2	43458	0.0832424
788187	taxon:9606	2.82653222	2.23E-05	178111	1902	retinoic acid receptor gamma	gene	biological_process-&-1&-GO:0008361-&&-regulation of cell size-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0031641-&&-regulation of myelination-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0002068-&&-glandular epithelial cell development-%%-GO:0001843-&&-neural tube closure-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0045637-&&-regulation of myeloid cell differentiation-%%-GO:0060324-&&-face development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0003406-&&-retinal pigment epithelium development-%%-GO:0070384-&&-Harderian gland development-%%-GO:0003430-&&-growth plate cartilage chondrocyte growth-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0060070-&&-canonical Wnt signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046965-&&-retinoid X receptor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding	G:9606:RARG				RARG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARG	0.35379041	0.1	25	4	FALSE	RARG	RARG	81.04	0	25	0	0.69557796	FALSE	0	RARG	28040	0.06511703
788238	taxon:9606	2.75957145	2.94E-05	178030	1902	SH2 domain containing adaptor protein B	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:SHB				SHB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHB	0.36237511	0.33666667	25	4	FALSE	SHB	SHB	129.04	0	25	0	0.70673809	FALSE	0	SHB	31454	0.08146557
788335	taxon:9606	2.55412006	1.82E-05	161479	1902	histone cluster 2 H2A family member b	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2AB			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST2H2AB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2AB	0.39152427	0.16666667	25	4	FALSE	HIST2H2AB	HIST2H2AB	246.84	0	25	0	0.74097999	FALSE	0	HIST2H2AB	42406	0.08610122
788374	taxon:9606	2.56010714	3.73E-05	177786	1902	SRP receptor alpha subunit	gene	biological_process-&-1&-GO:0006613-&&-cotranslational protein targeting to membrane-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005785-&&-signal recognition particle receptor complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005047-&&-signal recognition particle binding	G:9606:SRPRA			KEGG-&-1&-hsa03060-&&-Protein export	SRPRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRPRA	0.39060865	0.08333333	25	4	FALSE	SRPRA	SRPRA	196.08	0	25	0	0.73998214	FALSE	0	SRPRA	73988	0.06898204
788483	taxon:9606	2.63100677	5.46E-05	177564	1902	synaptosome associated protein 25	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:0016081-&&-synaptic vesicle docking-%%-GO:0008306-&&-associative learning-%%-GO:1990926-&&-short-term synaptic potentiation-%%-GO:0010975-&&-regulation of neuron projection development-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0099590-&&-neurotransmitter receptor internalization-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0031915-&&-positive regulation of synaptic plasticity-%%-GO:0031629-&&-synaptic vesicle fusion to presynaptic active zone membrane-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001504-&&-neurotransmitter uptake-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0016082-&&-synaptic vesicle priming-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0098967-&&-exocytic insertion of neurotransmitter receptor to postsynaptic membrane|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0031982-&&-vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0031201-&&-SNARE complex-%%-GO:0016020-&&-membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030426-&&-growth cone-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0098794-&&-postsynapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0070032-&&-synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex-%%-GO:0043209-&&-myelin sheath-%%-GO:0030054-&&-cell junction-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0043005-&&-neuron projection-%%-GO:0030424-&&-axon-%%-GO:0036477-&&-somatodendritic compartment|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:SNAP25			KEGG-&-1&-hsa04911-&&-Insulin secretion-%%-hsa04721-&&-Synaptic vesicle cycle	SNAP25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAP25	0.38008264	0.17666667	25	4	FALSE	SNAP25	SNAP25	134.56	0	25	0	0.72816554	FALSE	0	SNAP25	62668	0.05661331
788517	taxon:9606	2.76760674	5.74E-05	177519	1902	SRY-box 10	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048469-&&-cell maturation-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0061138-&&-morphogenesis of a branching epithelium-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0048484-&&-enteric nervous system development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0032808-&&-lacrimal gland development-%%-GO:0014015-&&-positive regulation of gliogenesis-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0048589-&&-developmental growth-%%-GO:0006366-&&-transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0031315-&&-extrinsic component of mitochondrial outer membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0042802-&&-identical protein binding	G:9606:SOX10				SOX10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX10	0.36132301	0.09090909	25	4	FALSE	SOX10	SOX10	125.826087	0	24	0	0.70539888	FALSE	1	SOX10	59672	0.07859846
788554	taxon:9606	2.75957145	3.42E-05	161066	1902	kelch like family member 38	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL38				KLHL38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL38	0.36237511	0.13333333	25	4	FALSE	KLHL38	KLHL38	118.32	0	25	0	0.70673809	FALSE	0	KLHL38	61726	0.07318041
788848	taxon:9606	2.72049787	2.85E-05	176759	1902	upstream transcription factor 2, c-fos interacting	gene	biological_process-&-1&-GO:0000430-&&-regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0055088-&&-lipid homeostasis-%%-GO:0000432-&&-positive regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007595-&&-lactation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019086-&&-late viral transcription|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0043425-&&-bHLH transcription factor binding	G:9606:USF2				USF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USF2	0.36757978	0.10671937	25	4	FALSE	USF2	USF2	133.3043478	0	24	0	0.71325035	FALSE	1	USF2	36644	0.07154384
788945	taxon:9606	2.72349141	2.23E-05	160170	1902	transmembrane protein 189	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TMEM189				TMEM189	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM189	0.36717575	0.12333333	25	4	FALSE	TMEM189	TMEM189	117	0	25	0	0.71275143	FALSE	0	TMEM189	40550	0.06379913
788975	taxon:9606	2.92847014	3.43E-05	176489	1902	zinc finger and SCAN domain containing 20	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZSCAN20				ZSCAN20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZSCAN20	0.34147522	0.03666667	25	4	FALSE	ZSCAN20	ZSCAN20	44.16	0	25	0	0.67858831	FALSE	0	ZSCAN20	30312	0.06215909
789061	taxon:9606	2.50275721	2.49E-05	176261	1902	dolichyl-phosphate mannosyltransferase subunit 1, catalytic	gene	biological_process-&-1&-GO:0035269-&&-protein O-linked mannosylation-%%-GO:0035268-&&-protein mannosylation-%%-GO:0019348-&&-dolichol metabolic process-%%-GO:0006506-&&-GPI anchor biosynthetic process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0033185-&&-dolichol-phosphate-mannose synthase complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004169-&&-dolichyl-phosphate-mannose-protein mannosyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004582-&&-dolichyl-phosphate beta-D-mannosyltransferase activity	G:9606:DPM1			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways	DPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPM1	0.39955933	0.08333333	25	4	FALSE	DPM1	DPM1	278.68	0	25	0	0.74954047	FALSE	0	DPM1	71198	0.087467
789081	taxon:9606	2.6284859	1.93E-05	176231	1902	kinase suppressor of ras 1	gene	biological_process-&-1&-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005078-&&-MAP-kinase scaffold activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:KSR1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway	KSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KSR1	0.38044716	0.24505929	25	4	FALSE	KSR1	KSR1	178.6956522	0	24	0	0.72858568	FALSE	1	KSR1	34970	0.07474475
789086	taxon:9606	2.7148259	5.04E-05	176218	1902	LIM domain binding 1	gene	biological_process-&-1&-GO:0046985-&&-positive regulation of hemoglobin biosynthetic process-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0022607-&&-cellular component assembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0021702-&&-cerebellar Purkinje cell differentiation-%%-GO:0043549-&&-regulation of kinase activity-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0001942-&&-hair follicle development-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0043973-&&-histone H3-K4 acetylation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030182-&&-neuron differentiation-%%-GO:0000972-&&-transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010669-&&-epithelial structure maintenance|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0031252-&&-cell leading edge-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0030274-&&-LIM domain binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043621-&&-protein self-association-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding	G:9606:LDB1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	LDB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDB1	0.36834775	0.09666667	25	5	FALSE	LDB1	LDB1	116.56	0	25	0	0.71419568	FALSE	0	LDB1	52068	0.06045738
789136	taxon:9606	2.73546557	3.58E-05	176135	1902	selenium binding protein 1	gene	biological_process-&-1&-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008430-&&-selenium binding-%%-GO:0005515-&&-protein binding	G:9606:SELENBP1				SELENBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELENBP1	0.36556848	0.05666667	25	4	FALSE	SELENBP1	SELENBP1	108.28	0	25	0	0.71075574	FALSE	0	SELENBP1	38922	0.06119115
789181	taxon:9606	2.54986608	2.50E-05	176043	1902	histone cluster 1 H2B family member l	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BL			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BL	0.39217746	0.14333333	25	4	FALSE	HIST1H2BL	HIST1H2BL	292.52	0	25	0	0.74168899	FALSE	0	HIST1H2BL	63948	0.10116263
789262	taxon:9606	2.74003466	3.95E-05	175880	1902	vesicle associated membrane protein 8	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0016240-&&-autophagosome docking-%%-GO:0043308-&&-eosinophil degranulation-%%-GO:0065009-&&-regulation of molecular function-%%-GO:1903531-&&-negative regulation of secretion by cell-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1903595-&&-positive regulation of histamine secretion by mast cell-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006906-&&-vesicle fusion-%%-GO:0070254-&&-mucus secretion-%%-GO:1903076-&&-regulation of protein localization to plasma membrane-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0097352-&&-autophagosome maturation|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031982-&&-vesicle-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005769-&&-early endosome-%%-GO:0031201-&&-SNARE complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0098594-&&-mucin granule-%%-GO:0016020-&&-membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0055038-&&-recycling endosome membrane|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding-%%-GO:0019869-&&-chloride channel inhibitor activity	G:9606:VAMP8			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04140-&&-Autophagy - animal-%%-hsa04611-&&-Platelet activation	VAMP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAMP8	0.36495889	0.13333333	25	4	FALSE	VAMP8	VAMP8	126.68	0	25	0	0.70999422	FALSE	0	VAMP8	56516	0.07188175
789352	taxon:9606	2.59098787	2.97E-05	175681	1902	programmed cell death 5	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:1903645-&&-negative regulation of chaperone-mediated protein folding-%%-GO:1903638-&&-positive regulation of protein import into mitochondrial outer membrane-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0010698-&&-acetyltransferase activator activity-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0008201-&&-heparin binding	G:9606:PDCD5				PDCD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDCD5	0.38595318	0.1	25	4	FALSE	PDCD5	PDCD5	203.12	0	25	0	0.73483536	FALSE	0	PDCD5	47104	0.0773913
789485	taxon:9606	2.75563258	2.18E-05	175363	1902	synuclein alpha interacting protein	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0008219-&&-cell death-%%-GO:0046928-&&-regulation of neurotransmitter secretion-%%-GO:0090083-&&-regulation of inclusion body assembly-%%-GO:0042417-&&-dopamine metabolic process|cellular_component-&-1&-GO:0042734-&&-presynaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SNCAIP			KEGG-&-1&-hsa05012-&&-Parkinson disease	SNCAIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNCAIP	0.36289308	0.11462451	25	4	FALSE	SNCAIP	SNCAIP	113.6956522	0	24	0	0.70739457	FALSE	1	SNCAIP	27924	0.06878572
789650	taxon:9606	2.72018276	7.51E-05	174973	1902	anaphase promoting complex subunit 10	gene	biological_process-&-1&-GO:0070979-&&-protein K11-linked ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0051439-&&-regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0051436-&&-negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle-%%-GO:0030071-&&-regulation of mitotic metaphase/anaphase transition-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051437-&&-positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005680-&&-anaphase-promoting complex-%%-GO:0005654-&&-nucleoplasm	G:9606:ANAPC10			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	ANAPC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANAPC10	0.36762236	0.30333333	25	4	FALSE	ANAPC10	ANAPC10	121.52	0	25	0	0.71330287	FALSE	0	ANAPC10	85472	0.06517167
789758	taxon:9606	2.64187805	3.08E-05	174756	1902	homeodomain interacting protein kinase 3	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0009299-&&-mRNA transcription-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:HIPK3			KEGG-&-1&-hsa04218-&&-Cellular senescence	HIPK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIPK3	0.37851861	0.13	25	4	FALSE	HIPK3	HIPK3	158.16	0	25	0	0.72635366	FALSE	0	HIPK3	47560	0.06829226
789770	taxon:9606	2.60989444	2.30E-05	174728	1902	SURP and G-patch domain containing 2	gene	biological_process-&-1&-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:SUGP2				SUGP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUGP2	0.38315726	0.1	25	4	FALSE	SUGP2	SUGP2	229.4	0	25	0	0.73168426	FALSE	0	SUGP2	56552	0.08985098
789778	taxon:9606	2.67764298	8.20E-06	174697	1902	RNA binding motif protein 5	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0006915-&&-apoptotic process-%%-GO:0006396-&&-RNA processing-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000166-&&-nucleotide binding	G:9606:RBM5				RBM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM5	0.37346278	0.19666667	25	4	FALSE	RBM5	RBM5	183.96	0	25	0	0.72039284	FALSE	0	RBM5	21236	0.08677998
789850	taxon:9606	2.60989444	2.25E-05	174514	1902	translocase of outer mitochondrial membrane 34	gene	biological_process-&-1&-GO:0006626-&&-protein targeting to mitochondrion|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:TOMM34				TOMM34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOMM34	0.38315726	0.23	25	4	FALSE	TOMM34	TOMM34	210.44	0	25	0	0.73168426	FALSE	0	TOMM34	38142	0.08345894
789919	taxon:9606	2.65936663	1.80E-05	174366	1902	CUGBP Elav-like family member 1	gene	biological_process-&-1&-GO:0007281-&&-germ cell development-%%-GO:0006397-&&-mRNA processing-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0009790-&&-embryo development-%%-GO:0006376-&&-mRNA splice site selection-%%-GO:0016246-&&-RNA interference-%%-GO:0043484-&&-regulation of RNA splicing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0042835-&&-BRE binding-%%-GO:0005515-&&-protein binding-%%-GO:0000900-&&-translation repressor activity, nucleic acid binding-%%-GO:0000166-&&-nucleotide binding	G:9606:CELF1				CELF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CELF1	0.37602939	0.14229249	25	5	FALSE	CELF1	CELF1	184.6956522	0	24	0	0.7234389	FALSE	1	CELF1	34982	0.08305915
789930	taxon:9606	2.80148101	1.03E-04	174334	1902	family with sequence similarity 189 member B	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding	G:9606:FAM189B				FAM189B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM189B	0.35695405	0.05	25	4	FALSE	FAM189B	FAM189B	76.36	0	25	0	0.69975316	FALSE	0	FAM189B	101350	0.05658464
790161	taxon:9606	2.67496455	1.00E-05	173732	1902	serine/threonine kinase 38 like	gene	biological_process-&-1&-GO:0051128-&&-regulation of cellular component organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:STK38L				STK38L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK38L	0.37383673	0.22	25	4	FALSE	STK38L	STK38L	287	0	25	0	0.72083924	FALSE	0	STK38L	35464	0.13452158
790175	taxon:9606	2.67874586	5.00E-05	173715	1902	ubiquitin specific peptidase 33	gene	biological_process-&-1&-GO:0010506-&&-regulation of autophagy-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0050821-&&-protein stabilization-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0051298-&&-centrosome duplication-%%-GO:0006897-&&-endocytosis-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0007411-&&-axon guidance-%%-GO:0070536-&&-protein K63-linked deubiquitination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005776-&&-autophagosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0044297-&&-cell body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030891-&&-VCB complex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:USP33				USP33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP33	0.37330902	0.11	25	4	FALSE	USP33	USP33	134.36	0	25	0	0.72020902	FALSE	0	USP33	54338	0.06430695
790321	taxon:9606	2.81172207	3.07E-05	173317	1902	NADH:ubiquinone oxidoreductase complex assembly factor 3	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NDUFAF3			KEGG-&-1&-hsa04714-&&-Thermogenesis	NDUFAF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFAF3	0.35565393	0.25333333	25	4	FALSE	NDUFAF3	NDUFAF3	83.88	0	25	0	0.69804632	FALSE	0	NDUFAF3	38958	0.06220238
790354	taxon:9606	2.75263904	3.09E-05	173240	1902	hes related family bHLH transcription factor with YRPW motif 2	gene	biological_process-&-1&-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0065004-&&-protein-DNA complex assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060411-&&-cardiac septum morphogenesis-%%-GO:0060948-&&-cardiac vascular smooth muscle cell development-%%-GO:0003199-&&-endocardial cushion to mesenchymal transition involved in heart valve formation-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0014031-&&-mesenchymal cell development-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0045607-&&-regulation of auditory receptor cell differentiation-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0003195-&&-tricuspid valve formation-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:2001212-&&-regulation of vasculogenesis-%%-GO:0060842-&&-arterial endothelial cell differentiation-%%-GO:0061314-&&-Notch signaling involved in heart development-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0036304-&&-umbilical cord morphogenesis-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0003214-&&-cardiac left ventricle morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0090102-&&-cochlea development-%%-GO:0097084-&&-vascular smooth muscle cell development-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0003186-&&-tricuspid valve morphogenesis-%%-GO:0003150-&&-muscular septum morphogenesis-%%-GO:0010621-&&-negative regulation of transcription by transcription factor localization-%%-GO:0001570-&&-vasculogenesis-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0060633-&&-negative regulation of transcription initiation from RNA polymerase II promoter-%%-GO:2000820-&&-negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0060347-&&-heart trabecula formation-%%-GO:2000723-&&-negative regulation of cardiac vascular smooth muscle cell differentiation-%%-GO:0061156-&&-pulmonary artery morphogenesis-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0060977-&&-coronary vasculature morphogenesis-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0035910-&&-ascending aorta morphogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0060413-&&-atrial septum morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016580-&&-Sin3 complex-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000988-&&-transcription factor activity, protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0035939-&&-microsatellite binding	G:9606:HEY2			KEGG-&-1&-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05165-&&-Human papillomavirus infection	HEY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEY2	0.36328773	0.09090909	25	4	FALSE	HEY2	HEY2	114.3913044	0	24	0	0.70789349	FALSE	1	HEY2	36682	0.06985773
790478	taxon:9606	2.51614936	2.53E-05	172732	1902	GTPase activating protein and VPS9 domains 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006897-&&-endocytosis-%%-GO:0007165-&&-signal transduction-%%-GO:0051223-&&-regulation of protein transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005768-&&-endosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0045296-&&-cadherin binding	G:9606:GAPVD1				GAPVD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAPVD1	0.39743269	0.17	25	4	FALSE	GAPVD1	GAPVD1	269.04	0	25	0	0.74730844	FALSE	0	GAPVD1	49958	0.0860967
790578	taxon:9606	2.83756105	4.23E-05	172090	1902	pyrophosphatase (inorganic) 2	gene	biological_process-&-1&-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0071344-&&-diphosphate metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004427-&&-inorganic diphosphatase activity-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:PPA2			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation	PPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPA2	0.35241532	0.02666667	25	4	FALSE	PPA2	PPA2	60.84	0	25	0	0.69373982	FALSE	0	PPA2	36758	0.05112807
790609	taxon:9606	2.62234126	2.18E-05	171764	1902	dishevelled binding antagonist of beta catenin 1	gene	biological_process-&-1&-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0048619-&&-embryonic hindgut morphogenesis-%%-GO:2000095-&&-regulation of Wnt signaling pathway, planar cell polarity pathway-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0021915-&&-neural tube development-%%-GO:1904864-&&-negative regulation of beta-catenin-TCF complex assembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:1900107-&&-regulation of nodal signaling pathway-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0035412-&&-regulation of catenin import into nucleus-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0030877-&&-beta-catenin destruction complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070097-&&-delta-catenin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0051018-&&-protein kinase A binding	G:9606:DACT1				DACT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DACT1	0.38133862	0.19666667	25	4	FALSE	DACT1	DACT1	204.04	0	25	0	0.72960979	FALSE	0	DACT1	39414	0.08362444
790617	taxon:9606	2.8607216	4.40E-05	171746	1902	testis expressed 264	gene	biological_process-&-1&-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TEX264				TEX264	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEX264	0.34956215	0.04666667	25	4	FALSE	TEX264	TEX264	62.04	0	25	0	0.68987973	FALSE	0	TEX264	38572	0.05840607
790675	taxon:9606	2.62328659	5.43E-06	171514	1902	SET domain containing 2	gene	biological_process-&-1&-GO:0048332-&&-mesoderm morphogenesis-%%-GO:0048864-&&-stem cell development-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0097198-&&-histone H3-K36 trimethylation-%%-GO:0097676-&&-histone H3-K36 dimethylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010793-&&-regulation of mRNA export from nucleus-%%-GO:0001525-&&-angiogenesis-%%-GO:0060039-&&-pericardium development-%%-GO:0034728-&&-nucleosome organization-%%-GO:0006298-&&-mismatch repair-%%-GO:0035441-&&-cell migration involved in vasculogenesis-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0060977-&&-coronary vasculature morphogenesis-%%-GO:0001763-&&-morphogenesis of a branching structure-%%-GO:0001843-&&-neural tube closure-%%-GO:0030900-&&-forebrain development-%%-GO:0060669-&&-embryonic placenta morphogenesis|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046975-&&-histone methyltransferase activity (H3-K36 specific)	G:9606:SETD2			KEGG-&-1&-hsa00310-&&-Lysine degradation	SETD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETD2	0.3812012	0.29249012	25	4	FALSE	SETD2	SETD2	321.4347826	0	24	0	0.72945223	FALSE	1	SETD2	25716	0.13036423
790770	taxon:9606	2.8144005	4.43E-05	171275	1902	ABI family member 3	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006928-&&-movement of cell or subcellular component|cellular_component-&-1&-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ABI3				ABI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABI3	0.35531546	0.08300395	25	5	FALSE	ABI3	ABI3	83.13043478	0	24	0	0.69759992	FALSE	1	ABI3	46656	0.06222847
790800	taxon:9606	2.53867969	8.15E-05	171164	1902	transportin 2	gene	biological_process-&-1&-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0006610-&&-ribosomal protein import into nucleus|cellular_component-&-1&-GO:0034399-&&-nuclear periphery-%%-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008139-&&-nuclear localization sequence binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:TNPO2				TNPO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNPO2	0.39390554	0.06666667	25	4	FALSE	TNPO2	TNPO2	200.44	0	25	0	0.74355338	FALSE	0	TNPO2	115856	0.0678196
790837	taxon:9606	2.77674492	4.68E-05	171006	1902	derlin 2	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:1904153-&&-negative regulation of retrograde protein transport, ER to cytosol-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001967-&&-suckling behavior-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DERL2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DERL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DERL2	0.36013391	0.18	25	4	FALSE	DERL2	DERL2	91.24	0	25	0	0.70387585	FALSE	0	DERL2	49858	0.0612223
790960	taxon:9606	2.67354656	2.86E-05	170590	1902	B-cell CLL/lymphoma 11A	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0016925-&&-protein sumoylation-%%-GO:0022008-&&-neurogenesis-%%-GO:2000173-&&-negative regulation of branching morphogenesis of a nerve-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903860-&&-negative regulation of dendrite extension-%%-GO:1905232-&&-cellular response to L-glutamate-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:1904800-&&-negative regulation of neuron remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000171-&&-negative regulation of dendrite development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:BCL11A	BCL11A	TRUE		BCL11A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL11A	0.37403501	0.18577075	25	5	FALSE	BCL11A	BCL11A	159.4347826	0	24	0	0.72107557	FALSE	1	BCL11A	39944	0.07438033
791055	taxon:9606	2.93823854	3.20E-05	170211	1902	cholinergic receptor nicotinic alpha 9 subunit	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0005892-&&-acetylcholine-gated channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0022848-&&-acetylcholine-gated cation-selective channel activity	G:9606:CHRNA9			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	CHRNA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHRNA9	0.34033996	0.01	25	4	FALSE	CHRNA9	CHRNA9	33.84	0	25	0	0.67696024	FALSE	0	CHRNA9	24978	0.05324717
791170	taxon:9606	2.47928155	2.91E-05	169832	1902	isoleucyl-tRNA synthetase 2, mitochondrial	gene	biological_process-&-1&-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0006428-&&-isoleucyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0004822-&&-isoleucine-tRNA ligase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding	G:9606:IARS2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	IARS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IARS2	0.40334265	0.15	25	4	FALSE	IARS2	IARS2	260.56	0	25	0	0.75345307	FALSE	0	IARS2	60698	0.07803475
791228	taxon:9606	2.60438002	4.76E-05	169663	1902	BAI1 associated protein 2 like 1	gene	biological_process-&-1&-GO:0009617-&&-response to bacterium-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0051764-&&-actin crosslink formation-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0046626-&&-regulation of insulin receptor signaling pathway-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0070064-&&-proline-rich region binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0005515-&&-protein binding	G:9606:BAIAP2L1				BAIAP2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAIAP2L1	0.38396854	0.07666667	25	4	FALSE	BAIAP2L1	BAIAP2L1	166.92	0	25	0	0.73260333	FALSE	0	BAIAP2L1	66500	0.06553459
791271	taxon:9606	2.57082086	3.02E-05	169422	1902	kinase D interacting substrate 220	gene	biological_process-&-1&-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0048813-&&-dendrite morphogenesis|cellular_component-&-1&-GO:0005770-&&-late endosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019887-&&-protein kinase regulator activity-%%-GO:0030165-&&-PDZ domain binding	G:9606:KIDINS220			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	KIDINS220	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIDINS220	0.38898082	0.12333333	25	4	FALSE	KIDINS220	KIDINS220	194.72	0	25	0	0.73819652	FALSE	0	KIDINS220	54238	0.07072337
791342	taxon:9606	2.6998582	1.49E-05	169082	1902	THAP domain containing 11	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:THAP11				THAP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THAP11	0.37038982	0.09486166	25	4	FALSE	THAP11	THAP11	143.3043478	0	24	0	0.7166903	FALSE	1	THAP11	25480	0.07166507
791359	taxon:9606	2.67969119	1.25E-05	169010	1902	mitochondrial ribosomal protein S14	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS14			KEGG-&-1&-hsa03010-&&-Ribosome	MRPS14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS14	0.37317733	0.25666667	25	4	FALSE	MRPS14	MRPS14	174.04	0	25	0	0.72005147	FALSE	0	MRPS14	27098	0.08289662
791441	taxon:9606	2.53505593	1.24E-05	168625	1902	mitochondrial ribosomal protein S34	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS34				MRPS34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS34	0.39446861	0.31666667	25	4	FALSE	MRPS34	MRPS34	314.12	0	25	0	0.74415734	FALSE	0	MRPS34	38100	0.10565758
791451	taxon:9606	2.59177564	7.81E-06	168590	1902	DExD-box helicase 50	gene	biological_process-&-1&-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX50				DDX50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX50	0.38583587	0.32333333	25	4	FALSE	DDX50	DDX50	324.88	0	25	0	0.73470406	FALSE	0	DDX50	27570	0.12324858
791762	taxon:9606	2.65337955	6.37E-05	166971	1902	pterin-4 alpha-carbinolamine dehydratase 2	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051289-&&-protein homotetramerization|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008124-&&-4-alpha-hydroxytetrahydrobiopterin dehydratase activity-%%-GO:0004505-&&-phenylalanine 4-monooxygenase activity-%%-GO:0005515-&&-protein binding	G:9606:PCBD2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	PCBD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCBD2	0.37687786	0.05533597	25	5	FALSE	PCBD2	PCBD2	144.6086957	0	24	0	0.72443674	FALSE	1	PCBD2	68348	0.06428738
791768	taxon:9606	2.51410115	2.04E-05	166957	1902	UTP15, small subunit processome component	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UTP15			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	UTP15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP15	0.39775647	0.23333333	25	4	FALSE	UTP15	UTP15	273.68	0	25	0	0.74764981	FALSE	0	UTP15	45328	0.08753679
791996	taxon:9606	2.73231448	4.73E-05	166369	1902	LON peptidase N-terminal domain and ring finger 1	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:LONRF1				LONRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LONRF1	0.36599008	0.06719368	25	5	FALSE	LONRF1	LONRF1	110.3478261	0	24	0	0.71128092	FALSE	1	LONRF1	45434	0.06149103
792001	taxon:9606	2.6284859	1.94E-05	166364	1902	ELM2 and Myb/SANT domain containing 1	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0000118-&&-histone deacetylase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ELMSAN1				ELMSAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELMSAN1	0.38044716	0.12666667	25	4	FALSE	ELMSAN1	ELMSAN1	193.28	0	25	0	0.72858568	FALSE	0	ELMSAN1	32206	0.08001658
792038	taxon:9606	2.86009138	3.61E-05	182697	1902	BCL2 interacting protein 3 like	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0097345-&&-mitochondrial outer membrane permeabilization-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0035694-&&-mitochondrial protein catabolic process-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0051607-&&-defense response to virus-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016607-&&-nuclear speck-%%-GO:0005739-&&-mitochondrion-%%-GO:0031224-&&-intrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005521-&&-lamin binding-%%-GO:0042802-&&-identical protein binding	G:9606:BNIP3L			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	BNIP3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNIP3L	0.34963918	0.07509881	25	4	FALSE	BNIP3L	BNIP3L	64.47826087	0	24	0	0.68998477	FALSE	1	BNIP3L	30228	0.06218402
792184	taxon:9606	2.74334331	2.49E-05	182465	1902	ras homolog family member B	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0001525-&&-angiogenesis-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0000910-&&-cytokinesis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0030154-&&-cell differentiation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005634-&&-nucleus-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding	G:9606:RHOB				RHOB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOB	0.36451872	0.06666667	25	4	FALSE	RHOB	RHOB	107.72	0	25	0	0.70944278	FALSE	0	RHOB	32024	0.06326074
792222	taxon:9606	2.6434536	7.96E-05	182390	1902	ATPase Na+/K+ transporting subunit alpha 3	gene	biological_process-&-1&-GO:0086036-&&-regulation of cardiac muscle cell membrane potential-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0090662-&&-ATP hydrolysis coupled transmembrane transport-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007613-&&-memory-%%-GO:0010248-&&-establishment or maintenance of transmembrane electrochemical gradient-%%-GO:0008542-&&-visual learning-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:0010107-&&-potassium ion import-%%-GO:1903416-&&-response to glycoside-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0042493-&&-response to drug-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0036376-&&-sodium ion export from cell-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0044326-&&-dendritic spine neck-%%-GO:0016021-&&-integral component of membrane-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0044327-&&-dendritic spine head-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0042383-&&-sarcolemma-%%-GO:0043209-&&-myelin sheath-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005890-&&-sodium:potassium-exchanging ATPase complex-%%-GO:0045202-&&-synapse-%%-GO:0030424-&&-axon|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:1990239-&&-steroid hormone binding-%%-GO:0043395-&&-heparan sulfate proteoglycan binding-%%-GO:0005391-&&-sodium:potassium-exchanging ATPase activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0086037-&&-sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential-%%-GO:0031748-&&-D1 dopamine receptor binding	G:9606:ATP1A3			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04978-&&-Mineral absorption-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP1A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP1A3	0.378293	0.11	25	4	FALSE	ATP1A3	ATP1A3	146.28	0	25	0	0.72609107	FALSE	0	ATP1A3	79982	0.06283254
792283	taxon:9606	2.69875532	7.32E-05	165910	1902	phosphatidylinositol glycan anchor biosynthesis class S	gene	biological_process-&-1&-GO:0016255-&&-attachment of GPI anchor to protein|cellular_component-&-1&-GO:0042765-&&-GPI-anchor transamidase complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003923-&&-GPI-anchor transamidase activity-%%-GO:0005515-&&-protein binding	G:9606:PIGS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00563-&&-Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	PIGS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIGS	0.37054119	0.06	25	4	FALSE	PIGS	PIGS	128.64	0	25	0	0.71687411	FALSE	0	PIGS	86854	0.06440984
792299	taxon:9606	2.6451867	5.81E-05	182261	1902	calmegin	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007338-&&-single fertilization-%%-GO:0007339-&&-binding of sperm to zona pellucida|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:CLGN				CLGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLGN	0.37804515	0.18	25	4	FALSE	CLGN	CLGN	153.84	0	25	0	0.72580222	FALSE	0	CLGN	67012	0.06686385
792342	taxon:9606	2.95336379	7.16E-05	165812	1902	glycoprotein integral membrane 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:GINM1				GINM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GINM1	0.33859696	0.01333333	25	4	FALSE	GINM1	GINM1	26.08	0	25	0	0.67443937	FALSE	0	GINM1	63946	0.04768362
792355	taxon:9606	2.61635418	3.11E-05	182171	1902	cytokine inducible SH2 containing protein	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:CISH			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	CISH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CISH	0.38221125	0.17	25	4	FALSE	CISH	CISH	171.64	0	25	0	0.73060764	FALSE	0	CISH	57936	0.06978031
792362	taxon:9606	2.65463999	4.08E-05	182156	1902	adaptor related protein complex 3 sigma 1 subunit	gene	biological_process-&-1&-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030119-&&-AP-type membrane coat adaptor complex-%%-GO:0030133-&&-transport vesicle-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030123-&&-AP-3 adaptor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:AP3S1			KEGG-&-1&-hsa04142-&&-Lysosome	AP3S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP3S1	0.37669891	0.12	25	4	FALSE	AP3S1	AP3S1	127.04	0	25	0	0.72422667	FALSE	0	AP3S1	48382	0.05621286
792756	taxon:9606	2.74586419	4.26E-05	181428	1902	fibrinogen alpha chain	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0072378-&&-blood coagulation, fibrin clot formation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0031639-&&-plasminogen activation-%%-GO:0043152-&&-induction of bacterial agglutination-%%-GO:0070527-&&-platelet aggregation-%%-GO:0051592-&&-response to calcium ion-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0006461-&&-protein complex assembly-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0051258-&&-protein polymerization-%%-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0042730-&&-fibrinolysis-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0072377-&&-blood coagulation, common pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007596-&&-blood coagulation-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005577-&&-fibrinogen complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:FGA			KEGG-&-1&-hsa04611-&&-Platelet activation-%%-hsa04610-&&-Complement and coagulation cascades	FGA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGA	0.36418407	0.1541502	25	4	FALSE	FGA	FGA	98.43478261	0	24	0	0.70902264	FALSE	1	FGA	45010	0.05841907
792777	taxon:9606	2.72947849	2.01E-05	181390	1902	down-regulator of transcription 1	gene	biological_process-&-1&-GO:0043966-&&-histone H3 acetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005671-&&-Ada2/Gcn5/Ada3 transcription activator complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:DR1				DR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DR1	0.36637035	0.15	25	4	FALSE	DR1	DR1	112.28	0	25	0	0.71175358	FALSE	0	DR1	31284	0.06168224
792782	taxon:9606	2.65621553	5.48E-05	181373	1902	epidermal growth factor	gene	biological_process-&-1&-GO:0090279-&&-regulation of calcium ion import-%%-GO:0061024-&&-membrane organization-%%-GO:1900127-&&-positive regulation of hyaluronan biosynthetic process-%%-GO:0006260-&&-DNA replication-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0001525-&&-angiogenesis-%%-GO:0007262-&&-STAT protein import into nucleus-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0044332-&&-Wnt signaling pathway involved in dorsal/ventral axis specification-%%-GO:0021940-&&-positive regulation of cerebellar granule cell precursor proliferation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007165-&&-signal transduction-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051048-&&-negative regulation of secretion-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0090370-&&-negative regulation of cholesterol efflux|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0030297-&&-transmembrane receptor protein tyrosine kinase activator activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:EGF	EGF	TRUE	KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa05219-&&-Bladder cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05226-&&-Gastric cancer	EGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGF	0.37647547	0.13043478	25	4	FALSE	EGF	EGF	150.5217391	0	24	0	0.72396408	FALSE	1	EGF	53942	0.06767418
792868	taxon:9606	2.68678116	2.59E-05	164866	1902	RNA binding motif protein 45	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM45				RBM45	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM45	0.37219258	0.13438735	25	4	FALSE	RBM45	RBM45	170.8695652	0	24	0	0.71886981	FALSE	1	RBM45	35318	0.08297895
792966	taxon:9606	2.84417835	2.27E-05	181073	1902	FK506 binding protein 1B	gene	biological_process-&-1&-GO:0014808-&&-release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0022417-&&-protein maturation by protein folding-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0048680-&&-positive regulation of axon regeneration-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0030073-&&-insulin secretion-%%-GO:0051284-&&-positive regulation of sequestering of calcium ion-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0033197-&&-response to vitamin E-%%-GO:0060314-&&-regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:0051775-&&-response to redox state-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0019227-&&-neuronal action potential propagation-%%-GO:0042098-&&-T cell proliferation-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0042026-&&-protein refolding-%%-GO:0009749-&&-response to glucose-%%-GO:0010459-&&-negative regulation of heart rate-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0061179-&&-negative regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0051280-&&-negative regulation of release of sequestered calcium ion into cytosol|cellular_component-&-1&-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030018-&&-Z disc-%%-GO:0034704-&&-calcium channel complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005528-&&-FK506 binding-%%-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005219-&&-ryanodine-sensitive calcium-release channel activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0030551-&&-cyclic nucleotide binding	G:9606:FKBP1B				FKBP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP1B	0.35159539	0.20333333	25	4	FALSE	FKBP1B	FKBP1B	77.4	0	25	0	0.69263694	FALSE	0	FKBP1B	28570	0.06819788
793006	taxon:9606	2.69465889	2.54E-05	164569	1902	ankyrin repeat and SOCS box containing 10	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ASB10				ASB10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB10	0.37110448	0.09	25	4	FALSE	ASB10	ASB10	149.56	0	25	0	0.71755685	FALSE	0	ASB10	42762	0.07426866
793097	taxon:9606	2.75862612	2.64E-05	180738	1902	GATA binding protein 4	gene	biological_process-&-1&-GO:0010507-&&-negative regulation of autophagy-%%-GO:0060575-&&-intestinal epithelial cell differentiation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0051891-&&-positive regulation of cardioblast differentiation-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008584-&&-male gonad development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0003197-&&-endocardial cushion development-%%-GO:0042493-&&-response to drug-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007492-&&-endoderm development-%%-GO:0003290-&&-atrial septum secundum morphogenesis-%%-GO:0033189-&&-response to vitamin A-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007596-&&-blood coagulation-%%-GO:0035054-&&-embryonic heart tube anterior/posterior pattern specification-%%-GO:0060290-&&-transdifferentiation-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0003281-&&-ventricular septum development-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0051525-&&-NFAT protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0070410-&&-co-SMAD binding	G:9606:GATA4			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04530-&&-Tight junction-%%-hsa04022-&&-cGMP-PKG signaling pathway	GATA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATA4	0.36249929	0.11333333	25	5	FALSE	GATA4	GATA4	122.4	0	25	0	0.70689565	FALSE	0	GATA4	34956	0.07267974
793258	taxon:9606	2.74917284	2.25E-05	164035	1902	homeodomain interacting protein kinase 4	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:HIPK4			KEGG-&-1&-hsa04218-&&-Cellular senescence	HIPK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIPK4	0.36374577	0.05666667	25	5	FALSE	HIPK4	HIPK4	104.2	0	25	0	0.70847119	FALSE	0	HIPK4	29204	0.06199641
793317	taxon:9606	2.73845911	1.30E-04	180320	1902	neuregulin 1	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0007399-&&-nervous system development-%%-GO:0021842-&&-chemorepulsion involved in interneuron migration from the subpallium to the cortex-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043496-&&-regulation of protein homodimerization activity-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0014032-&&-neural crest cell development-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0021781-&&-glial cell fate commitment-%%-GO:0038127-&&-ERBB signaling pathway-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007154-&&-cell communication-%%-GO:0009790-&&-embryo development-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0030879-&&-mammary gland development-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007416-&&-synapse assembly-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0051048-&&-negative regulation of secretion-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0060956-&&-endocardial cell differentiation-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0051155-&&-positive regulation of striated muscle cell differentiation-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0001964-&&-startle response-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0060379-&&-cardiac muscle cell myoblast differentiation-%%-GO:0042060-&&-wound healing-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0007626-&&-locomotory behavior-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0008366-&&-axon ensheathment-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045213-&&-neurotransmitter receptor metabolic process-%%-GO:2000010-&&-positive regulation of protein localization to cell surface|cellular_component-&-1&-GO:0030673-&&-axolemma-%%-GO:0044297-&&-cell body-%%-GO:0016020-&&-membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0045499-&&-chemorepellent activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0043125-&&-ErbB-3 class receptor binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0030297-&&-transmembrane receptor protein tyrosine kinase activator activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005176-&&-ErbB-2 class receptor binding	G:9606:NRG1	NRG1	TRUE	KEGG-&-1&-hsa04012-&&-ErbB signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	NRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRG1	0.36516886	0.05	25	4	FALSE	NRG1	NRG1	96.4	0	25	0	0.71025681	FALSE	0	NRG1	121114	0.05485126
787090	taxon:9606	2.46525918	1.08E-05	163697	1902	DAB2 interacting protein	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0036324-&&-vascular endothelial growth factor receptor-2 signaling pathway-%%-GO:0090129-&&-positive regulation of synapse maturation-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0040008-&&-regulation of growth-%%-GO:1900006-&&-positive regulation of dendrite development-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0043497-&&-regulation of protein heterodimerization activity-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0001525-&&-angiogenesis-%%-GO:0070317-&&-negative regulation of G0 to G1 transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0035148-&&-tube formation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:1900744-&&-regulation of p38MAPK cascade-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0034144-&&-negative regulation of toll-like receptor 4 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0038026-&&-reelin-mediated signaling pathway-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0043553-&&-negative regulation of phosphatidylinositol 3-kinase activity-%%-GO:1900747-&&-negative regulation of vascular endothelial growth factor signaling pathway-%%-GO:0007049-&&-cell cycle-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:1903363-&&-negative regulation of cellular protein catabolic process-%%-GO:0021814-&&-cell motility involved in cerebral cortex radial glia guided migration-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0006987-&&-activation of signaling protein activity involved in unfolded protein response-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0032809-&&-neuronal cell body membrane-%%-GO:0044301-&&-climbing fiber-%%-GO:0030425-&&-dendrite-%%-GO:1990597-&&-AIP1-IRE1 complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:1990032-&&-parallel fiber-%%-GO:0005737-&&-cytoplasm-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0044300-&&-cerebellar mossy fiber-%%-GO:0043025-&&-neuronal cell body-%%-GO:0031235-&&-intrinsic component of the cytoplasmic side of the plasma membrane|molecular_function-&-1&-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0045296-&&-cadherin binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0035591-&&-signaling adaptor activity-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0035662-&&-Toll-like receptor 4 binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0019900-&&-kinase binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0031434-&&-mitogen-activated protein kinase kinase binding-%%-GO:0071889-&&-14-3-3 protein binding-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding	G:9606:DAB2IP			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04210-&&-Apoptosis	DAB2IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAB2IP	0.40563686	0.21212121	24	4	FALSE	DAB2IP	DAB2IP	308.5454546	0	23	0	0.75579014	FALSE	1	DAB2IP	38678	0.09002043
787155	taxon:9606	2.74176776	1.02E-04	179970	1902	leucyl and cystinyl aminopeptidase	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0061024-&&-membrane organization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0030163-&&-protein catabolic process-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0007565-&&-female pregnancy-%%-GO:0043171-&&-peptide catabolic process|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane-%%-GO:0031905-&&-early endosome lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane|molecular_function-&-1&-GO:0008237-&&-metallopeptidase activity-%%-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:LNPEP			KEGG-&-1&-hsa04614-&&-Renin-angiotensin system	LNPEP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LNPEP	0.36472819	0.01086957	24	4	FALSE	LNPEP	LNPEP	99.54166667	0	24	0	0.70970537	FALSE	0	LNPEP	106806	0.05843195
787163	taxon:9606	2.64581692	3.53E-05	179945	1902	leukotriene A4 hydrolase	gene	biological_process-&-1&-GO:0019370-&&-leukotriene biosynthetic process-%%-GO:0006508-&&-proteolysis-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0043171-&&-peptide catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004463-&&-leukotriene-A4 hydrolase activity-%%-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0004301-&&-epoxide hydrolase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:LTA4H	LTA4H	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	LTA4H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTA4H	0.3779551	0.06884058	24	4	FALSE	LTA4H	LTA4H	182.9166667	0	24	0	0.72569718	FALSE	0	LTA4H	57506	0.07853047
787343	taxon:9606	2.62564991	6.85E-05	179623	1902	laminin subunit gamma 1	gene	biological_process-&-1&-GO:0007492-&&-endoderm development-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048731-&&-system development-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0070831-&&-basement membrane assembly-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0016477-&&-cell migration-%%-GO:0006461-&&-protein complex assembly-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0005606-&&-laminin-1 complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005604-&&-basement membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0043260-&&-laminin-11 complex-%%-GO:0005576-&&-extracellular region-%%-GO:0043259-&&-laminin-10 complex|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent	G:9606:LAMC1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05020-&&-Prion diseases-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer	LAMC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMC1	0.38085809	0.09057971	24	4	FALSE	LAMC1	LAMC1	149.6666667	0	24	0	0.72905835	FALSE	0	LAMC1	72876	0.06175903
787344	taxon:9606	2.62060816	4.45E-05	179622	1902	lysosomal associated membrane protein 1	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:0048102-&&-autophagic cell death-%%-GO:1902513-&&-regulation of organelle transport along microtubule-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0043323-&&-positive regulation of natural killer cell degranulation-%%-GO:0090160-&&-Golgi to lysosome transport-%%-GO:0072594-&&-establishment of protein localization to organelle-%%-GO:0008626-&&-granzyme-mediated apoptotic signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity|cellular_component-&-1&-GO:0097208-&&-alveolar lamellar body-%%-GO:0005886-&&-plasma membrane-%%-GO:0044754-&&-autolysosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005770-&&-late endosome-%%-GO:0061474-&&-phagolysosome membrane-%%-GO:0044194-&&-cytolytic granule-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0042470-&&-melanosome-%%-GO:0010008-&&-endosome membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0005771-&&-multivesicular body-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:LAMP1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome	LAMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMP1	0.38159081	0.0942029	24	4	FALSE	LAMP1	LAMP1	168.7083333	0	24	0	0.72989864	FALSE	0	LAMP1	57102	0.0689273
787372	taxon:9606	2.61950528	1.25E-05	179541	1902	v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog	gene	biological_process-&-1&-GO:0001502-&&-cartilage condensation-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0030324-&&-lung development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045607-&&-regulation of auditory receptor cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903800-&&-positive regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042733-&&-embryonic digit morphogenesis|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:MYCN	MYCN	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	MYCN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYCN	0.38175147	0.22826087	24	4	FALSE	MYCN	MYCN	196.7916667	0	24	0	0.73008245	FALSE	0	MYCN	27016	0.07947811
787393	taxon:9606	2.825902	1.61E-05	179504	1902	myogenin	gene	biological_process-&-1&-GO:0014878-&&-response to electrical stimulus involved in regulation of muscle adaptation-%%-GO:0048743-&&-positive regulation of skeletal muscle fiber development-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0014891-&&-striated muscle atrophy-%%-GO:0014737-&&-positive regulation of muscle atrophy-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0014873-&&-response to muscle activity involved in regulation of muscle adaptation-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0009629-&&-response to gravity-%%-GO:0042789-&&-mRNA transcription from RNA polymerase II promoter-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007049-&&-cell cycle-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0014732-&&-skeletal muscle atrophy-%%-GO:1903862-&&-positive regulation of oxidative phosphorylation-%%-GO:0071259-&&-cellular response to magnetism-%%-GO:0042693-&&-muscle cell fate commitment-%%-GO:1901739-&&-regulation of myoblast fusion-%%-GO:0001503-&&-ossification-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0014842-&&-regulation of skeletal muscle satellite cell proliferation-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032993-&&-protein-DNA complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0070888-&&-E-box binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:MYOG				MYOG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOG	0.35386931	0.12554113	24	4	FALSE	MYOG	MYOG	88.27272727	0	23	0	0.695683	FALSE	1	MYOG	20176	0.06769306
787398	taxon:9606	2.82007248	1.79E-05	179497	1902	NGFI-A binding protein 2	gene	biological_process-&-1&-GO:0045682-&&-regulation of epidermis development-%%-GO:0014037-&&-Schwann cell differentiation-%%-GO:0001958-&&-endochondral ossification-%%-GO:0008283-&&-cell proliferation-%%-GO:0007399-&&-nervous system development-%%-GO:0016480-&&-negative regulation of transcription from RNA polymerase III promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding	G:9606:NAB2				NAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAB2	0.35460082	0.0952381	24	4	FALSE	NAB2	NAB2	96.72727273	0	23	0	0.69665459	FALSE	1	NAB2	29216	0.07639389
787429	taxon:9606	2.7312116	5.87E-05	179448	1902	leptin receptor	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0046850-&&-regulation of bone remodeling-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006909-&&-phagocytosis-%%-GO:0030217-&&-T cell differentiation-%%-GO:0019953-&&-sexual reproduction-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0098868-&&-bone growth-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0045721-&&-negative regulation of gluconeogenesis-%%-GO:0060259-&&-regulation of feeding behavior-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0097009-&&-energy homeostasis-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0044321-&&-response to leptin-%%-GO:0007166-&&-cell surface receptor signaling pathway|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0038021-&&-leptin receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding	G:9606:LEPR	LEPR	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	LEPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LEPR	0.36613787	0.12121212	24	4	FALSE	LEPR	LEPR	119.9545455	0	23	0	0.71146473	FALSE	1	LEPR	56856	0.06733817
787499	taxon:9606	2.94233496	6.35E-05	179333	1902	matrix metallopeptidase 7	gene	biological_process-&-1&-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0007568-&&-aging-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0044849-&&-estrous cycle-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006508-&&-proteolysis-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0031667-&&-response to nutrient levels|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding	G:9606:MMP7			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	MMP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP7	0.33986613	0.10144928	24	4	FALSE	MMP7	MMP7	35.5	0	24	0	0.67627751	FALSE	0	MMP7	57516	0.05801861
787528	taxon:9606	2.58893966	2.09E-05	179255	1902	mutS homolog 3	gene	biological_process-&-1&-GO:0043570-&&-maintenance of DNA repeat elements-%%-GO:0006281-&&-DNA repair-%%-GO:0051096-&&-positive regulation of helicase activity-%%-GO:0045910-&&-negative regulation of DNA recombination-%%-GO:0006298-&&-mismatch repair|cellular_component-&-1&-GO:0032302-&&-MutSbeta complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032142-&&-single guanine insertion binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0032139-&&-dinucleotide insertion or deletion binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0032137-&&-guanine/thymine mispair binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0032181-&&-dinucleotide repeat insertion binding-%%-GO:0030983-&&-mismatched DNA binding	G:9606:MSH3			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	MSH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSH3	0.38625852	0.27173913	24	4	FALSE	MSH3	MSH3	222.875	0	24	0	0.73517672	FALSE	0	MSH3	39508	0.08364626
787595	taxon:9606	2.79643926	4.22E-05	179121	1902	nuclear factor, erythroid 2	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007599-&&-hemostasis-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008015-&&-blood circulation-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0050699-&&-WW domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFE2				NFE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFE2	0.35759761	0.18614719	24	4	FALSE	NFE2	NFE2	100.7727273	0	23	0	0.70059346	FALSE	1	NFE2	52164	0.0729249
787951	taxon:9606	2.86103671	5.36E-05	178522	1902	serpin family E member 1	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:2000098-&&-negative regulation of smooth muscle cell-matrix adhesion-%%-GO:0001300-&&-chronological cell aging-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0061044-&&-negative regulation of vascular wound healing-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0001525-&&-angiogenesis-%%-GO:0010757-&&-negative regulation of plasminogen activation-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007623-&&-circadian rhythm-%%-GO:0035491-&&-positive regulation of leukotriene production involved in inflammatory response-%%-GO:0042730-&&-fibrinolysis-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0010951-&&-negative regulation of endopeptidase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding	G:9606:SERPINE1	SERPINE1	TRUE	KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04218-&&-Cellular senescence-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa04066-&&-HIF-1 signaling pathway	SERPINE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINE1	0.34952365	0.07792208	24	4	FALSE	SERPINE1	SERPINE1	69.04545455	0	23	0	0.68982721	FALSE	1	SERPINE1	47712	0.06672833
788005	taxon:9606	2.7099417	4.20E-05	178413	1902	period circadian clock 1	gene	biological_process-&-1&-GO:0097167-&&-circadian regulation of translation-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009649-&&-entrainment of circadian clock-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0042634-&&-regulation of hair cycle-%%-GO:1900744-&&-regulation of p38MAPK cascade-%%-GO:0051591-&&-response to cAMP-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:2000323-&&-negative regulation of glucocorticoid receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0070888-&&-E-box binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:PER1			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04710-&&-Circadian rhythm-%%-hsa04713-&&-Circadian entrainment	PER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PER1	0.36901163	0.22101449	24	4	FALSE	PER1	PER1	126.5416667	0	24	0	0.71500972	FALSE	0	PER1	48186	0.06631671
788250	taxon:9606	2.58783677	4.90E-05	178001	1902	regulator of G-protein signaling 3	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS3			KEGG-&-1&-hsa04360-&&-Axon guidance	RGS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS3	0.38642314	0.1038961	24	4	FALSE	RGS3	RGS3	207.5454546	0	23	0	0.73536054	FALSE	1	RGS3	59950	0.07855001
788273	taxon:9606	2.6848905	3.54E-05	177967	1902	ribosomal protein S6 kinase A2	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0016301-&&-kinase activity	G:9606:RPS6KA2			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04720-&&-Long-term potentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04150-&&-mTOR signaling pathway	RPS6KA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA2	0.37245467	0.21212121	24	5	FALSE	RPS6KA2	RPS6KA2	156.3636364	0	23	0	0.71918492	FALSE	1	RPS6KA2	45018	0.07514539
788308	taxon:9606	2.70096108	2.17E-05	177909	1902	S100 calcium binding protein A1	gene	biological_process-&-1&-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:1901387-&&-positive regulation of voltage-gated calcium channel activity-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021762-&&-substantia nigra development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0008016-&&-regulation of heart contraction|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0043005-&&-neuron projection-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0044548-&&-S100 protein binding	G:9606:S100A1				S100A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A1	0.37023858	0.11688312	24	4	FALSE	S100A1	S100A1	129.4090909	0	23	0	0.71650649	FALSE	1	S100A1	31806	0.0662704
788531	taxon:9606	2.75815346	1.71E-05	177495	1902	thyroid hormone responsive	gene	biological_process-&-1&-GO:0046890-&&-regulation of lipid biosynthetic process-%%-GO:0010866-&&-regulation of triglyceride biosynthetic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:THRSP				THRSP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THRSP	0.36256141	0.08225108	24	5	FALSE	THRSP	THRSP	115.8636364	0	23	0	0.70697442	FALSE	1	THRSP	32538	0.07247079
788604	taxon:9606	2.67669765	9.57E-06	177362	1902	zinc finger E-box binding homeobox 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0048752-&&-semicircular canal morphogenesis-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0007389-&&-pattern specification process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007417-&&-central nervous system development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0051216-&&-cartilage development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045602-&&-negative regulation of endothelial cell differentiation-%%-GO:0008283-&&-cell proliferation-%%-GO:0010464-&&-regulation of mesenchymal cell proliferation-%%-GO:0051150-&&-regulation of smooth muscle cell differentiation-%%-GO:0006955-&&-immune response-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:ZEB1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer	ZEB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZEB1	0.37359468	0.19565217	24	4	FALSE	ZEB1	ZEB1	173.3333333	0	24	0	0.72055039	FALSE	0	ZEB1	21960	0.08232383
788689	taxon:9606	2.92090752	3.20E-04	160797	1902	C1q and tumor necrosis factor related protein 9	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005581-&&-collagen trimer|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:C1QTNF9				C1QTNF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QTNF9	0.34235935	0.01731602	24	4	FALSE	C1QTNF9	C1QTNF9	39.45454545	0	23	0	0.67984875	FALSE	1	C1QTNF9	292888	0.05617682
788880	taxon:9606	2.739562	2.00E-05	176703	1902	coronin 2A	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0051015-&&-actin filament binding	G:9606:CORO2A				CORO2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CORO2A	0.36502185	0.18478261	24	4	FALSE	CORO2A	CORO2A	146.0416667	0	24	0	0.710073	FALSE	0	CORO2A	32972	0.08498542
788954	taxon:9606	2.64424137	6.57E-05	176536	1902	protein phosphatase, Mg2+/Mn2+ dependent 1D	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009314-&&-response to radiation-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0009617-&&-response to bacterium-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0009267-&&-cellular response to starvation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity	G:9606:PPM1D			KEGG-&-1&-hsa04115-&&-p53 signaling pathway	PPM1D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPM1D	0.3781803	0.06521739	24	4	FALSE	PPM1D	PPM1D	165.1666667	0	24	0	0.72595977	FALSE	0	PPM1D	76566	0.07142082
788972	taxon:9606	2.84622656	5.85E-05	176501	1902	zinc finger protein 16	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:1901989-&&-positive regulation of cell cycle phase transition-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051301-&&-cell division-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0007049-&&-cell cycle-%%-GO:0072707-&&-cellular response to sodium dodecyl sulfate-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045654-&&-positive regulation of megakaryocyte differentiation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF16				ZNF16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF16	0.35134237	0.01449275	24	4	FALSE	ZNF16	ZNF16	66	0	24	0	0.69229557	FALSE	0	ZNF16	56282	0.05999388
789023	taxon:9606	2.58137703	1.83E-05	176358	1902	DiGeorge syndrome critical region gene 14	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0071013-&&-catalytic step 2 spliceosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:DGCR14				DGCR14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DGCR14	0.38739014	0.05797101	24	4	FALSE	DGCR14	DGCR14	225	0	24	0	0.73643716	FALSE	0	DGCR14	40090	0.08370619
789220	taxon:9606	2.72553963	4.27E-05	175974	1902	titin-cap	gene	biological_process-&-1&-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0048739-&&-cardiac muscle fiber development-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0001756-&&-somitogenesis-%%-GO:0035995-&&-detection of muscle stretch-%%-GO:0007512-&&-adult heart development-%%-GO:0030241-&&-skeletal muscle myosin thick filament assembly-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0048769-&&-sarcomerogenesis-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0045214-&&-sarcomere organization-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0006461-&&-protein complex assembly-%%-GO:0035994-&&-response to muscle stretch|cellular_component-&-1&-GO:0031674-&&-I band-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0070080-&&-titin Z domain binding-%%-GO:0036122-&&-BMP binding-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0031432-&&-titin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0044325-&&-ion channel binding-%%-GO:0051373-&&-FATZ binding	G:9606:TCAP				TCAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCAP	0.36689982	0.09782609	24	4	FALSE	TCAP	TCAP	111.2916667	0	24	0	0.71241006	FALSE	0	TCAP	47502	0.06232454
789239	taxon:9606	2.72223098	1.08E-05	175921	1902	regulatory factor X associated ankyrin containing protein	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0045171-&&-intercellular bridge-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RFXANK			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa05152-&&-Tuberculosis-%%-hsa05340-&&-Primary immunodeficiency	RFXANK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFXANK	0.36734576	0.10822511	24	5	FALSE	RFXANK	RFXANK	145.0909091	0	23	0	0.7129615	FALSE	1	RFXANK	20606	0.07892652
789359	taxon:9606	2.74680952	1.66E-05	175668	1902	exonuclease 1	gene	biological_process-&-1&-GO:0006298-&&-mismatch repair-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006260-&&-DNA replication-%%-GO:0045190-&&-isotype switching-%%-GO:0016446-&&-somatic hypermutation of immunoglobulin genes-%%-GO:0002455-&&-humoral immune response mediated by circulating immunoglobulin-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0090656-&&-t-circle formation-%%-GO:0000732-&&-strand displacement-%%-GO:0006310-&&-DNA recombination-%%-GO:0006281-&&-DNA repair-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0035312-&&-5'-3' exodeoxyribonuclease activity-%%-GO:0008409-&&-5'-3' exonuclease activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0051908-&&-double-stranded DNA 5'-3' exodeoxyribonuclease activity-%%-GO:0004523-&&-RNA-DNA hybrid ribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0045145-&&-single-stranded DNA 5'-3' exodeoxyribonuclease activity-%%-GO:0004527-&&-exonuclease activity-%%-GO:0048256-&&-flap endonuclease activity	G:9606:EXO1			KEGG-&-1&-hsa03430-&&-Mismatch repair	EXO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXO1	0.36405874	0.1884058	24	4	FALSE	EXO1	EXO1	150.1666667	0	24	0	0.70886508	FALSE	0	EXO1	27418	0.08797654
789440	taxon:9606	2.50496297	2.15E-05	175470	1902	phospholipase A2 activating protein	gene	biological_process-&-1&-GO:0010992-&&-ubiquitin homeostasis-%%-GO:0006954-&&-inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016005-&&-phospholipase A2 activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:PLAA			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PLAA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLAA	0.3992075	0.23913043	24	4	FALSE	PLAA	PLAA	255.5416667	0	24	0	0.74917284	FALSE	0	PLAA	43762	0.08091807
789524	taxon:9606	2.71939499	2.10E-05	175264	1902	COX17, cytochrome c oxidase copper chaperone	gene	biological_process-&-1&-GO:0006825-&&-copper ion transport-%%-GO:0007507-&&-heart development-%%-GO:0007420-&&-brain development-%%-GO:0033617-&&-mitochondrial respiratory chain complex IV assembly-%%-GO:0006091-&&-generation of precursor metabolites and energy|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0016531-&&-copper chaperone activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0005515-&&-protein binding	G:9606:COX17			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa01100-&&-Metabolic pathways	COX17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COX17	0.36772885	0.14285714	24	4	FALSE	COX17	COX17	141.3636364	0	23	0	0.71343417	FALSE	1	COX17	34062	0.07581457
789671	taxon:9606	2.61367575	1.73E-05	174924	1902	vav guanine nucleotide exchange factor 3	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0030168-&&-platelet activation-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0001525-&&-angiogenesis-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0006906-&&-vesicle fusion-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008361-&&-regulation of cell size-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity	G:9606:VAV3			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04660-&&-T cell receptor signaling pathway	VAV3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAV3	0.38260293	0.32971014	24	4	FALSE	VAV3	VAV3	197.8333333	0	24	0	0.73105404	FALSE	0	VAV3	33452	0.07933882
789680	taxon:9606	2.61241531	8.48E-06	174911	1902	peptidylprolyl isomerase H	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0006461-&&-protein complex assembly-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071001-&&-U4/U6 snRNP-%%-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0016018-&&-cyclosporin A binding-%%-GO:0005515-&&-protein binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PPIH			KEGG-&-1&-hsa03040-&&-Spliceosome	PPIH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIH	0.38278753	0.23809524	24	4	FALSE	PPIH	PPIH	247.6818182	0	23	0	0.73126411	FALSE	1	PPIH	24904	0.09879925
789682	taxon:9606	2.72207342	1.23E-05	174905	1902	prefoldin subunit 6	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0051131-&&-chaperone-mediated protein complex assembly|cellular_component-&-1&-GO:0016272-&&-prefoldin complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0051087-&&-chaperone binding	G:9606:PFDN6				PFDN6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFDN6	0.36736702	0.20652174	24	4	FALSE	PFDN6	PFDN6	121.125	0	24	0	0.71298776	FALSE	0	PFDN6	21998	0.06592683
789707	taxon:9606	2.88340948	1.44E-05	174849	1902	basic leucine zipper ATF-like transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0072539-&&-T-helper 17 cell differentiation-%%-GO:0002320-&&-lymphoid progenitor cell differentiation-%%-GO:0072540-&&-T-helper 17 cell lineage commitment-%%-GO:0001816-&&-cytokine production-%%-GO:0045190-&&-isotype switching-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0045064-&&-T-helper 2 cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0060218-&&-hematopoietic stem cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:BATF				BATF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BATF	0.34681165	0.43290043	24	4	FALSE	BATF	BATF	75.27272727	0	23	0	0.68609842	FALSE	1	BATF	16186	0.07768083
789717	taxon:9606	2.71198992	2.79E-05	174829	1902	SLU7 homolog, splicing factor	gene	biological_process-&-1&-GO:0000380-&&-alternative mRNA splicing, via spliceosome-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0034605-&&-cellular response to heat-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000389-&&-mRNA 3'-splice site recognition-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0006405-&&-RNA export from nucleus|cellular_component-&-1&-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030628-&&-pre-mRNA 3'-splice site binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000386-&&-second spliceosomal transesterification activity	G:9606:SLU7			KEGG-&-1&-hsa03040-&&-Spliceosome	SLU7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLU7	0.36873293	0.07971014	24	4	FALSE	SLU7	SLU7	128.5	0	24	0	0.71466835	FALSE	0	SLU7	45650	0.06682308
789912	taxon:9606	2.58405546	3.74E-05	174377	1902	calcium/calmodulin dependent protein kinase kinase 2	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0000165-&&-MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0061762-&&-CAMKK-AMPK signaling cascade-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0045859-&&-regulation of protein kinase activity|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042995-&&-cell projection-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:CAMKK2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	CAMKK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMKK2	0.3869886	0.08695652	24	4	FALSE	CAMKK2	CAMKK2	175.6666667	0	24	0	0.73599076	FALSE	0	CAMKK2	55840	0.06563201
789931	taxon:9606	2.58689144	5.52E-05	174324	1902	meningioma expressed antigen 5 (hyaluronidase)	gene	biological_process-&-1&-GO:0006517-&&-protein deglycosylation-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0006516-&&-glycoprotein catabolic process-%%-GO:0006044-&&-N-acetylglucosamine metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016231-&&-beta-N-acetylglucosaminidase activity-%%-GO:0004415-&&-hyalurononglucosaminidase activity	G:9606:MGEA5			KEGG-&-1&-hsa04931-&&-Insulin resistance	MGEA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGEA5	0.38656435	0.15942029	24	4	FALSE	MGEA5	MGEA5	176	0	24	0	0.73551809	FALSE	0	MGEA5	64028	0.06604394
789985	taxon:9606	2.63463053	9.17E-05	174186	1902	coatomer protein complex subunit zeta 1	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0030126-&&-COPI vesicle coat-%%-GO:0005789-&&-endoplasmic reticulum membrane	G:9606:COPZ1				COPZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COPZ1	0.37955986	0.23376623	24	4	FALSE	COPZ1	COPZ1	157.7272727	0	23	0	0.72756158	FALSE	1	COPZ1	96982	0.06610357
790090	taxon:9606	2.89144478	7.13E-05	173902	1902	disco interacting protein 2 homolog A	gene	biological_process-&-1&-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008152-&&-metabolic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003824-&&-catalytic activity	G:9606:DIP2A				DIP2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIP2A	0.34584786	0.04710145	24	5	FALSE	DIP2A	DIP2A	49.75	0	24	0	0.6847592	FALSE	0	DIP2A	55346	0.0524265
790101	taxon:9606	2.62391681	2.74E-05	173874	1902	exportin 6	gene	biological_process-&-1&-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:XPO6				XPO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO6	0.38110964	0.13043478	24	4	FALSE	XPO6	XPO6	155.125	0	24	0	0.7293472	FALSE	0	XPO6	44074	0.06382942
790396	taxon:9606	2.61273042	6.35E-05	173121	1902	protein phosphatase 1 regulatory subunit 15A	gene	biological_process-&-1&-GO:1903917-&&-positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0035308-&&-negative regulation of protein dephosphorylation-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:1902310-&&-positive regulation of peptidyl-serine dephosphorylation-%%-GO:0036496-&&-regulation of translational initiation by eIF2 alpha dephosphorylation-%%-GO:0060734-&&-regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032058-&&-positive regulation of translational initiation in response to stress-%%-GO:0006915-&&-apoptotic process-%%-GO:0070972-&&-protein localization to endoplasmic reticulum-%%-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0072542-&&-protein phosphatase activator activity-%%-GO:0019901-&&-protein kinase binding	G:9606:PPP1R15A			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PPP1R15A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R15A	0.38274136	0.13768116	24	4	FALSE	PPP1R15A	PPP1R15A	205.1666667	0	24	0	0.7312116	FALSE	0	PPP1R15A	74836	0.08195111
790449	taxon:9606	2.59776272	2.28E-05	172824	1902	Sad1 and UNC84 domain containing 2	gene	biological_process-&-1&-GO:0007097-&&-nuclear migration-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0021817-&&-nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0051642-&&-centrosome localization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0090292-&&-nuclear matrix anchoring at nuclear membrane-%%-GO:0031022-&&-nuclear migration along microfilament-%%-GO:0090286-&&-cytoskeletal anchoring at nuclear membrane-%%-GO:0007052-&&-mitotic spindle organization|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005639-&&-integral component of nuclear inner membrane-%%-GO:0034993-&&-LINC complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005521-&&-lamin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SUN2				SUN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUN2	0.38494663	0.06521739	24	4	FALSE	SUN2	SUN2	177.4166667	0	24	0	0.73370621	FALSE	0	SUN2	41218	0.06851458
790557	taxon:9606	2.60359225	1.52E-05	172140	1902	RAN binding protein 6	gene	biological_process-&-1&-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0006610-&&-ribosomal protein import into nucleus|cellular_component-&-1&-GO:0034399-&&-nuclear periphery-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:RANBP6				RANBP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RANBP6	0.38408472	0.12681159	24	4	FALSE	RANBP6	RANBP6	188.7083333	0	24	0	0.73273463	FALSE	0	RANBP6	31214	0.07333787
790558	taxon:9606	2.60674334	6.24E-05	172137	1902	HMG-box transcription factor 1	gene	biological_process-&-1&-GO:0007050-&&-cell cycle arrest-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:HBP1				HBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBP1	0.38362043	0.0942029	24	4	FALSE	HBP1	HBP1	189.125	0	24	0	0.73220944	FALSE	0	HBP1	68156	0.07419059
790635	taxon:9606	2.56814243	1.58E-05	155313	1902	LSM12 pseudogene 1	gene		G:9606:LSM12P1				LSM12P1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM12P1	0.3893865	0.24275362	24	4	FALSE	LSM12P1	LSM12P1	280.6666667	0	24	0	0.73864293	FALSE	0	LSM12P1	36064	0.10124203
790639	taxon:9606	2.54939341	2.93E-05	171689	1902	exocyst complex component 6	gene	biological_process-&-1&-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0000145-&&-exocyst|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EXOC6				EXOC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC6	0.39225017	0.32467532	24	4	FALSE	EXOC6	EXOC6	195	0	23	0	0.74176776	FALSE	1	EXOC6	42276	0.06712565
790839	taxon:9606	2.77816291	2.73E-05	170997	1902	WASH complex subunit 3	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0071203-&&-WASH complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:WASHC3			KEGG-&-1&-hsa04144-&&-Endocytosis	WASHC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WASHC3	0.35995009	0.13768116	24	4	FALSE	WASHC3	WASHC3	92.70833333	0	24	0	0.70363951	FALSE	0	WASHC3	31242	0.06088268
790883	taxon:9606	2.74208287	1.12E-04	170780	1902	thioredoxin domain containing 11	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006457-&&-protein folding-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:TXNDC11				TXNDC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNDC11	0.36468628	0.03623188	24	5	FALSE	TXNDC11	TXNDC11	103.9583333	0	24	0	0.70965285	FALSE	0	TXNDC11	132396	0.06094271
790888	taxon:9606	2.68299984	5.47E-05	170770	1902	mediator of cell motility 1	gene	biological_process-&-1&-GO:0032886-&&-regulation of microtubule-based process-%%-GO:2000145-&&-regulation of cell motility|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MEMO1				MEMO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEMO1	0.37271713	0.03985507	24	4	FALSE	MEMO1	MEMO1	133.625	0	24	0	0.71950003	FALSE	0	MEMO1	63164	0.06350342
790907	taxon:9606	2.88073105	2.32E-05	170727	1902	selenocysteine lyase	gene	biological_process-&-1&-GO:0001887-&&-selenium compound metabolic process-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0009000-&&-selenocysteine lyase activity-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding	G:9606:SCLY			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00450-&&-Selenocompound metabolism	SCLY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCLY	0.34713411	0.10144928	24	4	FALSE	SCLY	SCLY	56.41666667	0	24	0	0.68654482	FALSE	0	SCLY	19432	0.05891859
790939	taxon:9606	2.69402867	1.86E-05	170656	1902	ankyrin repeat and SOCS box containing 4	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:2001214-&&-positive regulation of vasculogenesis|cellular_component-&-1&-GO:0031466-&&-Cul5-RING ubiquitin ligase complex-%%-GO:0031462-&&-Cul2-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:ASB4				ASB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB4	0.3711913	0.11255411	24	4	FALSE	ASB4	ASB4	162.3636364	0	23	0	0.71766189	FALSE	1	ASB4	32870	0.08045951
790966	taxon:9606	2.91602332	3.26E-05	170564	1902	FK506 binding protein 14	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005509-&&-calcium ion binding	G:9606:FKBP14				FKBP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP14	0.34293279	0	24	4	FALSE	FKBP14	FKBP14	158.5833333	0	24	0	0.68066278	FALSE	0	FKBP14	51616	0.20254927
790977	taxon:9606	2.674807	1.81E-05	170534	1902	uveal autoantigen with coiled-coil domains and ankyrin repeats	gene	biological_process-&-1&-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:UACA				UACA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UACA	0.37385875	0.06521739	24	4	FALSE	UACA	UACA	154.75	0	24	0	0.7208655	FALSE	0	UACA	33588	0.07263752
791001	taxon:9606	2.72711517	2.13E-05	170452	1902	regulator of microtubule dynamics 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0000922-&&-spindle pole-%%-GO:0005634-&&-nucleus-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RMDN3				RMDN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RMDN3	0.36668785	0.09782609	24	4	FALSE	RMDN3	RMDN3	141	0	24	0	0.71214747	FALSE	0	RMDN3	33412	0.0781973
791225	taxon:9606	2.67559477	2.49E-05	169669	1902	PDZ binding kinase	gene	biological_process-&-1&-GO:0007067-&&-mitotic nuclear division-%%-GO:0034644-&&-cellular response to UV-%%-GO:0032873-&&-negative regulation of stress-activated MAPK cascade-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050728-&&-negative regulation of inflammatory response|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:PBK				PBK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PBK	0.37374868	0.04761905	24	4	FALSE	PBK	PBK	146	0	23	0	0.72073421	FALSE	1	PBK	39020	0.06871834
791414	taxon:9606	2.71072948	4.18E-05	168742	1902	membrane associated ring-CH-type finger 7	gene	biological_process-&-1&-GO:0002643-&&-regulation of tolerance induction-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0042130-&&-negative regulation of T cell proliferation|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity	G:9606:MARCH7				7-Mar	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCH7	0.36890439	0.12121212	24	4	FALSE	7-Mar	7-Mar	147.7272727	0	23	0	0.71487842	FALSE	1	7-Mar	52388	0.07691213
791415	taxon:9606	2.71151725	2.72E-05	168734	1902	ubiquitin specific peptidase 46	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0008343-&&-adult feeding behavior-%%-GO:0001662-&&-behavioral fear response-%%-GO:0060013-&&-righting reflex|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:USP46				USP46	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP46	0.36879721	0.11594203	24	4	FALSE	USP46	USP46	122.375	0	24	0	0.71474712	FALSE	0	USP46	37708	0.06435405
791562	taxon:9606	2.77579959	4.86E-05	168033	1902	acidic residue methyltransferase 1	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0032259-&&-methylation-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0006974-&&-cellular response to DNA damage stimulus|molecular_function-&-1&-GO:0051998-&&-protein carboxyl O-methyltransferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity	G:9606:ARMT1				ARMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARMT1	0.36025656	0.05797101	24	4	FALSE	ARMT1	ARMT1	89.08333333	0	24	0	0.7040334	FALSE	0	ARMT1	39768	0.05861955
791643	taxon:9606	2.71498346	4.24E-05	167611	1902	thioredoxin related transmembrane protein 1	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006457-&&-protein folding-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0003756-&&-protein disulfide isomerase activity	G:9606:TMX1				TMX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMX1	0.36832637	0.08333333	24	4	FALSE	TMX1	TMX1	130.875	0	24	0	0.71416942	FALSE	0	TMX1	55834	0.07011541
791652	taxon:9606	2.72869072	1.50E-05	167574	1902	acidic nuclear phosphoprotein 32 family member E	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0043486-&&-histone exchange|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000812-&&-Swr1 complex-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0019212-&&-phosphatase inhibitor activity-%%-GO:0042393-&&-histone binding	G:9606:ANP32E				ANP32E	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANP32E	0.36647612	0.11231884	24	4	FALSE	ANP32E	ANP32E	114.875	0	24	0	0.71188488	FALSE	0	ANP32E	25850	0.06321127
791691	taxon:9606	2.66204506	6.63E-05	167410	1902	integrator complex subunit 5	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0016180-&&-snRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0032039-&&-integrator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:INTS5				INTS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INTS5	0.37565104	0.21014493	24	4	FALSE	INTS5	INTS5	144.4166667	0	24	0	0.72299249	FALSE	0	INTS5	71192	0.06536022
791869	taxon:9606	2.55553805	3.51E-05	182953	1902	aconitase 2	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0001889-&&-liver development-%%-GO:0006101-&&-citrate metabolic process-%%-GO:0006102-&&-isocitrate metabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0035900-&&-response to isolation stress|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0043209-&&-myelin sheath-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051538-&&-3 iron, 4 sulfur cluster binding-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0003994-&&-aconitate hydratase activity-%%-GO:0005506-&&-iron ion binding	G:9606:ACO2			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	ACO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACO2	0.39130703	0.15217391	24	4	FALSE	ACO2	ACO2	205.5	0	24	0	0.74074366	FALSE	0	ACO2	51946	0.0720547
791922	taxon:9606	2.8192847	2.93E-05	182875	1902	5'-aminolevulinate synthase 1	gene	biological_process-&-1&-GO:0006782-&&-protoporphyrinogen IX biosynthetic process-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006783-&&-heme biosynthetic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003870-&&-5-aminolevulinate synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0042802-&&-identical protein binding	G:9606:ALAS1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa00260-&&-Glycine, serine and threonine metabolism	ALAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALAS1	0.3546999	0.02164502	24	4	FALSE	ALAS1	ALAS1	76.72727273	0	23	0	0.69678588	FALSE	1	ALAS1	28118	0.05979544
791925	taxon:9606	2.79612415	3.82E-05	182865	1902	aldehyde dehydrogenase 3 family member B1	gene	biological_process-&-1&-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0046185-&&-aldehyde catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006068-&&-ethanol catabolic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0006066-&&-alcohol metabolic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031982-&&-vesicle|molecular_function-&-1&-GO:0004030-&&-aldehyde dehydrogenase [NAD(P)+] activity-%%-GO:0004028-&&-3-chloroallyl aldehyde dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:ALDH3B1			KEGG-&-1&-hsa00340-&&-Histidine metabolism-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa00360-&&-Phenylalanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05204-&&-Chemical carcinogenesis	ALDH3B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH3B1	0.35763791	0.09782609	24	4	FALSE	ALDH3B1	ALDH3B1	100.0833333	0	24	0	0.70064597	FALSE	0	ALDH3B1	51970	0.06920315
792202	taxon:9606	2.87017489	7.51E-05	182425	1902	asialoglycoprotein receptor 2	gene	biological_process-&-1&-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030282-&&-bone mineralization-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0055088-&&-lipid homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005515-&&-protein binding-%%-GO:0004873-&&-asialoglycoprotein receptor activity	G:9606:ASGR2			KEGG-&-1&-hsa04918-&&-Thyroid hormone synthesis	ASGR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASGR2	0.34841083	0.04761905	24	4	FALSE	ASGR2	ASGR2	57.13636364	0	23	0	0.68830419	FALSE	1	ASGR2	77248	0.05792314
792545	taxon:9606	2.56814243	1.58E-05	165447	1902	LSM12 homolog	gene		G:9606:LSM12				LSM12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM12	0.3893865	0.24275362	24	4	FALSE	LSM12	LSM12	280.6666667	0	24	0	0.73864293	FALSE	0	LSM12	36064	0.10124203
792567	taxon:9606	2.81566094	4.78E-05	165412	1902	CKLF like MARVEL transmembrane domain containing 5	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0045662-&&-negative regulation of myoblast differentiation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:CMTM5				CMTM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMTM5	0.3551564	0.02173913	24	4	FALSE	CMTM5	CMTM5	70.20833333	0	24	0	0.69738984	FALSE	0	CMTM5	44590	0.05534579
792679	taxon:9606	2.75705058	2.94E-05	181572	1902	dihydrolipoamide branched chain transacylase E2	gene	biological_process-&-1&-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0009083-&&-branched-chain amino acid catabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005947-&&-mitochondrial alpha-ketoglutarate dehydrogenase complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0043754-&&-dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	G:9606:DBT			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism	DBT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBT	0.36270644	0.08695652	24	4	FALSE	DBT	DBT	113.25	0	24	0	0.70715824	FALSE	0	DBT	39662	0.06891906
792717	taxon:9606	2.6351032	3.63E-05	181504	1902	NAD(P)H quinone dehydrogenase 1	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007584-&&-response to nutrient-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0007568-&&-aging-%%-GO:0009636-&&-response to toxic substance-%%-GO:0032355-&&-response to estradiol-%%-GO:0045471-&&-response to ethanol-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004128-&&-cytochrome-b5 reductase activity, acting on NAD(P)H-%%-GO:0004784-&&-superoxide dismutase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003955-&&-NAD(P)H dehydrogenase (quinone) activity	G:9606:NQO1	NQO1	TRUE	KEGG-&-1&-hsa00130-&&-Ubiquinone and other terpenoid-quinone biosynthesis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma	NQO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NQO1	0.37949178	0.11255411	24	4	FALSE	NQO1	NQO1	188.7727273	0	23	0	0.7274828	FALSE	1	NQO1	55310	0.07973773
792847	taxon:9606	2.77453915	2.12E-05	181274	1902	nuclear receptor subfamily 2 group F member 6	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048666-&&-neuron development-%%-GO:0007165-&&-signal transduction-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0030522-&&-intracellular receptor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004887-&&-thyroid hormone receptor activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:NR2F6				NR2F6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR2F6	0.36042022	0.0952381	24	5	FALSE	NR2F6	NR2F6	118.2272727	0	23	0	0.70424347	FALSE	1	NR2F6	27866	0.07499566
792939	taxon:9606	2.57822593	4.86E-05	181114	1902	acyl-CoA synthetase long-chain family member 4	gene	biological_process-&-1&-GO:0007584-&&-response to nutrient-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0060996-&&-dendritic spine development-%%-GO:0015908-&&-fatty acid transport-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0070672-&&-response to interleukin-15-%%-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0060136-&&-embryonic process involved in female pregnancy-%%-GO:0006641-&&-triglyceride metabolic process|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0044233-&&-ER-mitochondrion membrane contact site|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004467-&&-long-chain fatty acid-CoA ligase activity-%%-GO:0047676-&&-arachidonate-CoA ligase activity-%%-GO:0102391-&&-decanoate--CoA ligase activity-%%-GO:0031957-&&-very long-chain fatty acid-CoA ligase activity	G:9606:ACSL4			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa04714-&&-Thermogenesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa04216-&&-Ferroptosis-%%-hsa00071-&&-Fatty acid degradation	ACSL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACSL4	0.3878636	0.07608696	24	4	FALSE	ACSL4	ACSL4	185.9583333	0	24	0	0.73696234	FALSE	0	ACSL4	70882	0.06838118
792992	taxon:9606	2.69465889	1.55E-04	181034	1902	fms related tyrosine kinase 4	gene	biological_process-&-1&-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0038084-&&-vascular endothelial growth factor signaling pathway-%%-GO:0001944-&&-vasculature development-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0048286-&&-lung alveolus development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0001945-&&-lymph vessel development-%%-GO:0035924-&&-cellular response to vascular endothelial growth factor stimulus-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0060312-&&-regulation of blood vessel remodeling-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0003016-&&-respiratory system process-%%-GO:0090037-&&-positive regulation of protein kinase C signaling-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005524-&&-ATP binding	G:9606:FLT4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer	FLT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLT4	0.37110448	0.12987013	24	4	FALSE	FLT4	FLT4	137.9090909	0	23	0	0.71755685	FALSE	1	FLT4	196036	0.06959438
793027	taxon:9606	2.67969119	2.13E-05	180875	1902	growth factor receptor bound protein 14	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007165-&&-signal transduction-%%-GO:0009967-&&-positive regulation of signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity	G:9606:GRB14				GRB14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRB14	0.37317733	0.0995671	24	4	FALSE	GRB14	GRB14	146.2727273	0	23	0	0.72005147	FALSE	1	GRB14	35044	0.0700122
793107	taxon:9606	2.78147156	3.66E-05	180722	1902	GTP cyclohydrolase 1	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0014916-&&-regulation of lung blood pressure-%%-GO:0042311-&&-vasodilation-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0050884-&&-neuromuscular process controlling posture-%%-GO:0042559-&&-pteridine-containing compound biosynthetic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0035998-&&-7,8-dihydroneopterin 3'-triphosphate biosynthetic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0046654-&&-tetrahydrofolate biosynthetic process-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0048265-&&-response to pain-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0034341-&&-response to interferon-gamma|cellular_component-&-1&-GO:0044306-&&-neuron projection terminus-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0050662-&&-coenzyme binding-%%-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003934-&&-GTP cyclohydrolase I activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding	G:9606:GCH1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	GCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCH1	0.35952192	0.03896104	24	4	FALSE	GCH1	GCH1	95.68181818	0	23	0	0.70308807	FALSE	1	GCH1	38542	0.06370938
793187	taxon:9606	2.76997006	7.17E-05	180563	1902	haptoglobin	gene	biological_process-&-1&-GO:0010942-&&-positive regulation of cell death-%%-GO:0006953-&&-acute-phase response-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0051354-&&-negative regulation of oxidoreductase activity-%%-GO:0006952-&&-defense response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:2000296-&&-negative regulation of hydrogen peroxide catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031838-&&-haptoglobin-hemoglobin complex-%%-GO:0035580-&&-specific granule lumen-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0030492-&&-hemoglobin binding-%%-GO:0005515-&&-protein binding-%%-GO:0016209-&&-antioxidant activity	G:9606:HP	HP	TRUE		HP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HP	0.36101473	0.05434783	24	4	FALSE	HP	HP	87	0	24	0	0.70500499	FALSE	0	HP	62170	0.05601314
793278	taxon:9606	2.71907988	3.16E-06	180381	1902	histone cluster 1 H2A family member d	gene	biological_process-&-1&-GO:0006342-&&-chromatin silencing-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2AD			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa04217-&&-Necroptosis	HIST1H2AD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2AD	0.36777147	0.42028986	24	4	FALSE	HIST1H2AD	HIST1H2AD	214.8333333	0	24	0	0.71348669	FALSE	0	HIST1H2AD	10698	0.1150241
793348	taxon:9606	2.8224358	8.90E-05	180256	1902	heme oxygenase 1	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0034605-&&-cellular response to heat-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0043627-&&-response to estrogen-%%-GO:0043305-&&-negative regulation of mast cell degranulation-%%-GO:0001525-&&-angiogenesis-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0016242-&&-negative regulation of macroautophagy-%%-GO:1904036-&&-negative regulation of epithelial cell apoptotic process-%%-GO:0007588-&&-excretion-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0008219-&&-cell death-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0031670-&&-cellular response to nutrient-%%-GO:0035094-&&-response to nicotine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0042167-&&-heme catabolic process-%%-GO:0032764-&&-negative regulation of mast cell cytokine production-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0010656-&&-negative regulation of muscle cell apoptotic process-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0072719-&&-cellular response to cisplatin-%%-GO:0002246-&&-wound healing involved in inflammatory response-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0006788-&&-heme oxidation-%%-GO:0014806-&&-smooth muscle hyperplasia-%%-GO:0071243-&&-cellular response to arsenic-containing substance-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0002686-&&-negative regulation of leukocyte migration-%%-GO:0034395-&&-regulation of transcription from RNA polymerase II promoter in response to iron-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0097421-&&-liver regeneration|cellular_component-&-1&-GO:0005901-&&-caveola-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004392-&&-heme oxygenase (decyclizing) activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding-%%-GO:0004630-&&-phospholipase D activity-%%-GO:0004871-&&-signal transducer activity	G:9606:HMOX1	HMOX1	TRUE	KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa01100-&&-Metabolic pathways-%%-hsa05200-&&-Pathways in cancer-%%-hsa04978-&&-Mineral absorption-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa04216-&&-Ferroptosis-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	HMOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMOX1	0.3543039	0.03896104	24	4	FALSE	HMOX1	HMOX1	72.45454545	0	23	0	0.6962607	FALSE	1	HMOX1	67874	0.05924455
787074	taxon:9606	2.89837719	4.74E-04	180118	1902	insulin like growth factor 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0001503-&&-ossification-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0038028-&&-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0001501-&&-skeletal system development-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:2000467-&&-positive regulation of glycogen (starch) synthase activity-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0030546-&&-receptor activator activity-%%-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0005158-&&-insulin receptor binding	G:9606:IGF2	IGF2	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma	IGF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF2	0.34502066	0.0513834	23	5	FALSE	IGF2	IGF2	43.69565217	0	23	0	0.6836038	FALSE	0	IGF2	402180	0.0553764
787124	taxon:9606	2.73168426	3.10E-05	180021	1902	interleukin 16	gene	biological_process-&-1&-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006955-&&-immune response-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005125-&&-cytokine activity	G:9606:IL16			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	IL16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL16	0.36607452	0.04761905	23	4	FALSE	IL16	IL16	120.8095238	0	22	0	0.71138596	FALSE	1	IL16	36334	0.06915709
787171	taxon:9606	2.67449189	3.11E-05	179925	1902	SH2 domain containing 1A	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006959-&&-humoral immune response-%%-GO:0006968-&&-cellular defense response-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0050776-&&-regulation of immune response-%%-GO:0002250-&&-adaptive immune response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:SH2D1A			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05162-&&-Measles	SH2D1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D1A	0.3739028	0.27619048	23	5	FALSE	SH2D1A	SH2D1A	176.2857143	0	22	0	0.72091802	FALSE	1	SH2D1A	35368	0.08322649
787178	taxon:9606	2.62265637	1.48E-05	179913	1902	MAX dimerization protein 1	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:MXD1				MXD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MXD1	0.3812928	0.24761905	23	4	FALSE	MXD1	MXD1	194.5238095	0	22	0	0.72955727	FALSE	1	MXD1	27806	0.07944289
787191	taxon:9606	2.48857728	2.70E-05	163516	1902	additional sex combs like 1, transcriptional regulator	gene	biological_process-&-1&-GO:0032526-&&-response to retinoic acid-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0048538-&&-thymus development-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0060430-&&-lung saccule development-%%-GO:0048386-&&-positive regulation of retinoic acid receptor signaling pathway-%%-GO:0048387-&&-negative regulation of retinoic acid receptor signaling pathway-%%-GO:0048539-&&-bone marrow development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035522-&&-monoubiquitinated histone H2A deubiquitination-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030097-&&-hemopoiesis-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0035359-&&-negative regulation of peroxisome proliferator activated receptor signaling pathway|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035517-&&-PR-DUB complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0042974-&&-retinoic acid receptor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046872-&&-metal ion binding	G:9606:ASXL1				ASXL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASXL1	0.40183602	0.2055336	23	4	FALSE	ASXL1	ASXL1	268.5652174	0	23	0	0.75190379	FALSE	0	ASXL1	54288	0.0821803
787250	taxon:9606	2.87253821	3.25E-05	179802	1902	immunoglobulin superfamily containing leucine rich repeat	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031093-&&-platelet alpha granule lumen	G:9606:ISLR				ISLR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISLR	0.34812418	0.02766798	23	4	FALSE	ISLR	ISLR	60.30434783	0	23	0	0.6879103	FALSE	0	ISLR	29110	0.06211826
787383	taxon:9606	2.59807783	4.75E-05	179520	1902	myosin light chain kinase	gene	biological_process-&-1&-GO:0014820-&&-tonic smooth muscle contraction-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0032060-&&-bleb assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0060414-&&-aorta smooth muscle tissue morphogenesis-%%-GO:0071476-&&-cellular hypotonic response-%%-GO:0006936-&&-muscle contraction-%%-GO:0051928-&&-positive regulation of calcium ion transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001725-&&-stress fiber-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004687-&&-myosin light chain kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYLK			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MYLK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYLK	0.38489994	0.18972332	23	4	FALSE	MYLK	MYLK	199.5217391	0	23	0	0.73365369	FALSE	0	MYLK	64416	0.07698506
787445	taxon:9606	2.79722704	3.85E-05	179423	1902	midkine (neurite growth-promoting factor 2)	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0016477-&&-cell migration-%%-GO:0030421-&&-defecation-%%-GO:0030154-&&-cell differentiation-%%-GO:0030325-&&-adrenal gland development-%%-GO:0001662-&&-behavioral fear response-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009611-&&-response to wounding-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0042493-&&-response to drug-%%-GO:0021681-&&-cerebellar granular layer development-%%-GO:0050795-&&-regulation of behavior-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0007614-&&-short-term memory-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0051384-&&-response to glucocorticoid|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0008083-&&-growth factor activity	G:9606:MDK				MDK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MDK	0.3574969	0.04285714	23	5	FALSE	MDK	MDK	92.33333333	0	22	0	0.70046216	FALSE	1	MDK	39664	0.06829527
787573	taxon:9606	2.59933827	5.24E-05	162769	1902	ubiquitin specific peptidase 12	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:USP12				USP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP12	0.3847133	0.18577075	23	4	FALSE	USP12	USP12	171.2608696	0	23	0	0.73344362	FALSE	0	USP12	64722	0.06659564
787591	taxon:9606	2.54167323	3.60E-05	179130	1902	neurofibromin 1	gene	biological_process-&-1&-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0007420-&&-brain development-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0048820-&&-hair follicle maturation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0030325-&&-adrenal gland development-%%-GO:0008542-&&-visual learning-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0098597-&&-observational learning-%%-GO:0001666-&&-response to hypoxia-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007406-&&-negative regulation of neuroblast proliferation-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0014044-&&-Schwann cell development-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0048853-&&-forebrain morphogenesis-%%-GO:0043473-&&-pigmentation-%%-GO:0021510-&&-spinal cord development-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0001953-&&-negative regulation of cell-matrix adhesion-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0035021-&&-negative regulation of Rac protein signal transduction-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0021897-&&-forebrain astrocyte development-%%-GO:0050890-&&-cognition-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0007154-&&-cell communication-%%-GO:0021764-&&-amygdala development-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0045685-&&-regulation of glial cell differentiation-%%-GO:0048745-&&-smooth muscle tissue development-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0042060-&&-wound healing-%%-GO:0061535-&&-glutamate secretion, neurotransmission-%%-GO:0001656-&&-metanephros development-%%-GO:0001889-&&-liver development-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0045762-&&-positive regulation of adenylate cyclase activity-%%-GO:0061534-&&-gamma-aminobutyric acid secretion, neurotransmission-%%-GO:0021915-&&-neural tube development-%%-GO:0042992-&&-negative regulation of transcription factor import into nucleus-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0043535-&&-regulation of blood vessel endothelial cell migration-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:1900271-&&-regulation of long-term synaptic potentiation-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0046929-&&-negative regulation of neurotransmitter secretion-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0048712-&&-negative regulation of astrocyte differentiation|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031235-&&-intrinsic component of the cytoplasmic side of the plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:NF1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	NF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NF1	0.39344161	0.1027668	23	4	FALSE	NF1	NF1	217.173913	0	23	0	0.74305446	FALSE	0	NF1	59290	0.07412249
787727	taxon:9606	2.64439893	2.52E-05	178867	1902	DNA polymerase delta 2, accessory subunit	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006260-&&-DNA replication-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0000723-&&-telomere maintenance-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006298-&&-mismatch repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0043625-&&-delta DNA polymerase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0005515-&&-protein binding	G:9606:POLD2			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03410-&&-Base excision repair-%%-hsa03440-&&-Homologous recombination-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	POLD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLD2	0.37815777	0.13043478	23	4	FALSE	POLD2	POLD2	153.173913	0	23	0	0.72593351	FALSE	0	POLD2	34140	0.06605243
787764	taxon:9606	2.73987711	2.76E-05	178821	1902	cathepsin A	gene	biological_process-&-1&-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:1904714-&&-regulation of chaperone-mediated autophagy-%%-GO:0006508-&&-proteolysis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:1904715-&&-negative regulation of chaperone-mediated autophagy-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region-%%-GO:0098575-&&-lumenal side of lysosomal membrane|molecular_function-&-1&-GO:0004308-&&-exo-alpha-sialidase activity-%%-GO:0004180-&&-carboxypeptidase activity-%%-GO:0004185-&&-serine-type carboxypeptidase activity-%%-GO:0008047-&&-enzyme activator activity	G:9606:CTSA			KEGG-&-1&-hsa04614-&&-Renin-angiotensin system-%%-hsa04142-&&-Lysosome	CTSA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSA	0.36497987	0.12380952	23	4	FALSE	CTSA	CTSA	123.7142857	0	22	0	0.71002048	FALSE	1	CTSA	33750	0.07146988
787805	taxon:9606	2.55459272	2.33E-05	178761	1902	protein kinase cAMP-dependent type I regulatory subunit beta	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007611-&&-learning or memory-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005952-&&-cAMP-dependent protein kinase complex-%%-GO:0097546-&&-ciliary base|molecular_function-&-1&-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030552-&&-cAMP binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PRKAR1B			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway	PRKAR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKAR1B	0.39145183	0.21428571	23	4	FALSE	PRKAR1B	PRKAR1B	216.0476191	0	22	0	0.74090121	FALSE	1	PRKAR1B	40246	0.07539267
787857	taxon:9606	2.61603907	1.41E-05	178705	1902	phosphoribosyl pyrophosphate synthetase associated protein 1	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0043086-&&-negative regulation of catalytic activity|molecular_function-&-1&-GO:0004749-&&-ribose phosphate diphosphokinase activity-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:PRPSAP1				PRPSAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRPSAP1	0.38225729	0.12857143	23	4	FALSE	PRPSAP1	PRPSAP1	204.7142857	0	22	0	0.73066015	FALSE	1	PRPSAP1	30584	0.08242201
787991	taxon:9606	2.90231605	2.42E-05	178440	1902	platelet derived growth factor receptor like	gene	biological_process-&-1&-GO:0035791-&&-platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004992-&&-platelet activating factor receptor activity-%%-GO:0005019-&&-platelet-derived growth factor beta-receptor activity	G:9606:PDGFRL				PDGFRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFRL	0.34455241	0.01976285	23	5	FALSE	PDGFRL	PDGFRL	50.17391304	0	23	0	0.68294732	FALSE	0	PDGFRL	25900	0.06338263
788176	taxon:9606	2.79817236	3.37E-05	178126	1902	ral guanine nucleotide dissociation stimulator	gene	biological_process-&-1&-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005903-&&-brush border-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030695-&&-GTPase regulator activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:RALGDS			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer	RALGDS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RALGDS	0.35737613	0.12252964	23	4	FALSE	RALGDS	RALGDS	92.7826087	0	23	0	0.70030461	FALSE	0	RALGDS	35386	0.06774594
788300	taxon:9606	2.72616984	4.26E-05	177934	1902	related RAS viral (r-ras) oncogene homolog	gene	biological_process-&-1&-GO:0060325-&&-face morphogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0002521-&&-leukocyte differentiation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0051896-&&-regulation of protein kinase B signaling|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0019003-&&-GDP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:RRAS			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04360-&&-Axon guidance-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04137-&&-Mitophagy - animal	RRAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRAS	0.366815	0.20948617	23	4	FALSE	RRAS	RRAS	145.1304348	0	23	0	0.71230503	FALSE	0	RRAS	46554	0.08146067
788315	taxon:9606	2.64140539	1.96E-05	177903	1902	S100 calcium binding protein A6	gene	biological_process-&-1&-GO:0007409-&&-axonogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005635-&&-nuclear envelope-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0001726-&&-ruffle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0015075-&&-ion transmembrane transporter activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005523-&&-tropomyosin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0044548-&&-S100 protein binding	G:9606:S100A6				S100A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A6	0.37858634	0.15714286	23	4	FALSE	S100A6	S100A6	196.8095238	0	22	0	0.72643244	FALSE	1	S100A6	29598	0.0832728
788409	taxon:9606	2.59587207	4.69E-05	177721	1902	syntaxin binding protein 3	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0030073-&&-insulin secretion-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0070527-&&-platelet aggregation-%%-GO:0015758-&&-glucose transport-%%-GO:0007420-&&-brain development-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis-%%-GO:0032868-&&-response to insulin-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022615-&&-protein to membrane docking|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031091-&&-platelet alpha granule-%%-GO:0042581-&&-specific granule-%%-GO:0070820-&&-tertiary granule|molecular_function-&-1&-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017075-&&-syntaxin-1 binding	G:9606:STXBP3	STXBP3	TRUE		STXBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STXBP3	0.385227	0.28458498	23	4	FALSE	STXBP3	STXBP3	204.173913	0	23	0	0.73402132	FALSE	0	STXBP3	54290	0.07773085
788436	taxon:9606	2.71860722	3.07E-05	177675	1902	single-minded family bHLH transcription factor 2	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030324-&&-lung development-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SIM2				SIM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIM2	0.36783541	0.19762846	23	4	FALSE	SIM2	SIM2	138.3913044	0	23	0	0.71356546	FALSE	0	SIM2	37390	0.0736124
788446	taxon:9606	2.68504805	2.78E-05	177656	1902	solute carrier family 2 member 1	gene	biological_process-&-1&-GO:0006970-&&-response to osmotic stress-%%-GO:0042908-&&-xenobiotic transport-%%-GO:0005989-&&-lactose biosynthetic process-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0015758-&&-glucose transport-%%-GO:0019852-&&-L-ascorbic acid metabolic process-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:1904659-&&-glucose transmembrane transport-%%-GO:0070837-&&-dehydroascorbic acid transport-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0072562-&&-blood microparticle-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0042470-&&-melanosome-%%-GO:0001939-&&-female pronucleus-%%-GO:0016020-&&-membrane-%%-GO:0005901-&&-caveola-%%-GO:0030496-&&-midbody-%%-GO:0016323-&&-basolateral plasma membrane|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding-%%-GO:0005355-&&-glucose transmembrane transporter activity-%%-GO:0019900-&&-kinase binding-%%-GO:0042910-&&-xenobiotic transporter activity-%%-GO:0033300-&&-dehydroascorbic acid transporter activity-%%-GO:0055056-&&-D-glucose transmembrane transporter activity-%%-GO:0042802-&&-identical protein binding	G:9606:SLC2A1	SLC2A1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04931-&&-Insulin resistance-%%-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04976-&&-Bile secretion-%%-hsa04066-&&-HIF-1 signaling pathway	SLC2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC2A1	0.37243281	0.08695652	23	4	FALSE	SLC2A1	SLC2A1	162.3043478	0	23	0	0.71915866	FALSE	0	SLC2A1	39362	0.07962824
788459	taxon:9606	2.5769655	5.46E-05	177615	1902	solute carrier family 12 member 2	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0045795-&&-positive regulation of cell volume-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0006810-&&-transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0030321-&&-transepithelial chloride transport-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0070634-&&-transepithelial ammonium transport-%%-GO:0072488-&&-ammonium transmembrane transport-%%-GO:0006813-&&-potassium ion transport-%%-GO:0015696-&&-ammonium transport-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0016324-&&-apical plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0008511-&&-sodium:potassium:chloride symporter activity-%%-GO:0008519-&&-ammonium transmembrane transporter activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:SLC12A2			KEGG-&-1&-hsa04970-&&-Salivary secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04972-&&-Pancreatic secretion	SLC12A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC12A2	0.38805331	0.07142857	23	4	FALSE	SLC12A2	SLC12A2	234.9047619	0	22	0	0.73717242	FALSE	1	SLC12A2	77070	0.08636324
788513	taxon:9606	2.52654798	2.28E-05	177527	1902	SOS Ras/Rho guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051057-&&-positive regulation of small GTPase mediated signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:SOS2			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04540-&&-Gap junction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SOS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOS2	0.39579696	0.35573123	23	4	FALSE	SOS2	SOS2	271.8695652	0	23	0	0.74557534	FALSE	0	SOS2	47506	0.08951996
788564	taxon:9606	2.59681739	1.03E-04	177425	1902	ADAM metallopeptidase domain 17	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0048870-&&-cell motility-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0002467-&&-germinal center formation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0051088-&&-PMA-inducible membrane protein ectodomain proteolysis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0033025-&&-regulation of mast cell apoptotic process-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0030183-&&-B cell differentiation-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0055099-&&-response to high density lipoprotein particle-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006508-&&-proteolysis-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0042493-&&-response to drug-%%-GO:0035625-&&-epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway-%%-GO:0048536-&&-spleen development-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0051272-&&-positive regulation of cellular component movement-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005138-&&-interleukin-6 receptor binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005112-&&-Notch binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005178-&&-integrin binding	G:9606:ADAM17			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	ADAM17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAM17	0.38508676	0.11067194	23	4	FALSE	ADAM17	ADAM17	171.5652174	0	23	0	0.73386377	FALSE	0	ADAM17	121770	0.06649914
788614	taxon:9606	2.61824484	3.28E-06	160922	1902	heterogeneous nuclear ribonucleoprotein C-like 1	gene	cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:HNRNPCL1				HNRNPCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPCL1	0.38193525	0.29644269	23	4	FALSE	HNRNPCL1	HNRNPCL1	299.0869565	0	23	0	0.73029253	FALSE	0	HNRNPCL1	13240	0.1205024
788630	taxon:9606	2.55931936	6.98E-06	177286	1902	transcription factor A, mitochondrial	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033108-&&-mitochondrial respiratory chain complex assembly-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006391-&&-transcription initiation from mitochondrial promoter-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0006390-&&-transcription from mitochondrial promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0070363-&&-mitochondrial light strand promoter sense binding-%%-GO:0005515-&&-protein binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:TFAM	TFAM	TRUE	KEGG-&-1&-hsa04371-&&-Apelin signaling pathway-%%-hsa05016-&&-Huntington disease	TFAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAM	0.39072888	0.13833992	23	4	FALSE	TFAM	TFAM	324.7391304	0	23	0	0.74011344	FALSE	0	TFAM	26116	0.114774
788670	taxon:9606	2.84890499	1.62E-04	177220	1902	TIMP metallopeptidase inhibitor 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032487-&&-regulation of Rap protein signal transduction-%%-GO:0034097-&&-response to cytokine-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:0007417-&&-central nervous system development-%%-GO:1905049-&&-negative regulation of metallopeptidase activity-%%-GO:0007568-&&-aging-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0009725-&&-response to hormone-%%-GO:0045762-&&-positive regulation of adenylate cyclase activity-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0030426-&&-growth cone-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0005178-&&-integrin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0002020-&&-protease binding	G:9606:TIMP2	TIMP2	TRUE		TIMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMP2	0.35101206	0.04347826	23	4	FALSE	TIMP2	TIMP2	69.2173913	0	23	0	0.69184917	FALSE	0	TIMP2	211730	0.06460329
788771	taxon:9606	2.64313849	3.64E-06	176940	1902	PR/SET domain 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0034968-&&-histone lysine methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:PRDM2			KEGG-&-1&-hsa00310-&&-Lysine degradation	PRDM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDM2	0.3783381	0.39047619	23	4	FALSE	PRDM2	PRDM2	356.8095238	0	22	0	0.72614358	FALSE	1	PRDM2	15780	0.15226714
788968	taxon:9606	2.62249882	2.97E-05	176515	1902	B-TFIID TATA-box binding protein associated factor 1	gene	biological_process-&-1&-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:BTAF1				BTAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTAF1	0.38131571	0.04347826	23	4	FALSE	BTAF1	BTAF1	206.4782609	0	23	0	0.72958353	FALSE	0	BTAF1	69590	0.08373984
788993	taxon:9606	2.72238853	1.57E-05	160049	1902	ubiquitin specific peptidase 50	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP50				USP50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP50	0.3673245	0.0513834	23	4	FALSE	USP50	USP50	136	0	23	0	0.71293524	FALSE	0	USP50	27312	0.07427536
789010	taxon:9606	2.54151568	4.53E-05	176389	1902	A-kinase anchoring protein 1	gene	biological_process-&-1&-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0005515-&&-protein binding	G:9606:AKAP1				AKAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP1	0.393466	0.11857708	23	4	FALSE	AKAP1	AKAP1	190.6086957	0	23	0	0.74308072	FALSE	0	AKAP1	57280	0.06509104
789053	taxon:9606	2.7364109	1.99E-05	176276	1902	TNF receptor superfamily member 10a	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0036462-&&-TRAIL-activated apoptotic signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006915-&&-apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0071260-&&-cellular response to mechanical stimulus|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0045569-&&-TRAIL binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0005035-&&-death receptor activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0004872-&&-receptor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:TNFRSF10A			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04210-&&-Apoptosis-%%-hsa05164-&&-Influenza A-%%-hsa04217-&&-Necroptosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF10A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF10A	0.36544219	0.22857143	23	4	FALSE	TNFRSF10A	TNFRSF10A	121.4285714	0	22	0	0.71059818	FALSE	1	TNFRSF10A	23652	0.07037896
789101	taxon:9606	2.47817867	5.68E-05	176192	1902	eukaryotic translation initiation factor 2B subunit epsilon	gene	biological_process-&-1&-GO:0009408-&&-response to heat-%%-GO:0035690-&&-cellular response to drug-%%-GO:0021766-&&-hippocampus development-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0010226-&&-response to lithium ion-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0006413-&&-translational initiation-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0007568-&&-aging-%%-GO:0042552-&&-myelination-%%-GO:0009749-&&-response to glucose-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0014002-&&-astrocyte development-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005851-&&-eukaryotic translation initiation factor 2B complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:EIF2B5			KEGG-&-1&-hsa03013-&&-RNA transport	EIF2B5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2B5	0.40352216	0.256917	23	4	FALSE	EIF2B5	EIF2B5	247.1304348	0	23	0	0.75363689	FALSE	0	EIF2B5	83138	0.07407601
789225	taxon:9606	2.65227667	2.96E-05	175966	1902	pyridoxal kinase	gene	biological_process-&-1&-GO:0042816-&&-vitamin B6 metabolic process-%%-GO:0009443-&&-pyridoxal 5'-phosphate salvage-%%-GO:0016310-&&-phosphorylation-%%-GO:0042823-&&-pyridoxal phosphate biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030955-&&-potassium ion binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0031402-&&-sodium ion binding-%%-GO:0008478-&&-pyridoxal kinase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031403-&&-lithium ion binding	G:9606:PDXK			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00750-&&-Vitamin B6 metabolism	PDXK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDXK	0.37703457	0.12380952	23	4	FALSE	PDXK	PDXK	235.4285714	0	22	0	0.72462056	FALSE	1	PDXK	43664	0.10333501
789353	taxon:9606	2.74554908	4.60E-05	175683	1902	CBFA2/RUNX1 translocation partner 2	gene	biological_process-&-1&-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060575-&&-intestinal epithelial cell differentiation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:CBFA2T2				CBFA2T2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBFA2T2	0.36422587	0.18571429	23	4	FALSE	CBFA2T2	CBFA2T2	116	0	22	0	0.70907515	FALSE	1	CBFA2T2	43346	0.06799128
789534	taxon:9606	2.74586419	2.82E-05	175240	1902	ADP ribosylation factor guanine nucleotide exchange factor 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0015031-&&-protein transport-%%-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0010256-&&-endomembrane system organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007032-&&-endosome organization-%%-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0001881-&&-receptor recycling-%%-GO:0006887-&&-exocytosis|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030054-&&-cell junction-%%-GO:0032280-&&-symmetric synapse-%%-GO:0043197-&&-dendritic spine-%%-GO:0032279-&&-asymmetric synapse-%%-GO:0055037-&&-recycling endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005879-&&-axonemal microtubule-%%-GO:0005829-&&-cytosol-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0050811-&&-GABA receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017022-&&-myosin binding-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity	G:9606:ARFGEF2			KEGG-&-1&-hsa04144-&&-Endocytosis	ARFGEF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGEF2	0.36418407	0.07905138	23	4	FALSE	ARFGEF2	ARFGEF2	107	0	23	0	0.70902264	FALSE	0	ARFGEF2	34172	0.06240947
789560	taxon:9606	2.60059871	3.63E-05	175187	1902	Rho guanine nucleotide exchange factor 11	gene	biological_process-&-1&-GO:0006941-&&-striated muscle contraction-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0000910-&&-cytokinesis-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity	G:9606:ARHGEF11			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05200-&&-Pathways in cancer-%%-hsa05163-&&-Human cytomegalovirus infection	ARHGEF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF11	0.38452684	0.1952381	23	4	FALSE	ARHGEF11	ARHGEF11	216.4761905	0	22	0	0.73323355	FALSE	1	ARHGEF11	52176	0.08372033
789577	taxon:9606	2.77989601	4.56E-05	175146	1902	FCH and double SH3 domains 2	gene	biological_process-&-1&-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0030833-&&-regulation of actin filament polymerization|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FCHSD2				FCHSD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCHSD2	0.35972569	0.06666667	23	4	FALSE	FCHSD2	FCHSD2	99.85714286	0	22	0	0.70335066	FALSE	1	FCHSD2	42396	0.06616575
789721	taxon:9606	2.56956042	3.00E-05	174827	1902	SIVA1 apoptosis inducing factor	gene	biological_process-&-1&-GO:0046718-&&-viral entry into host cell-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0005175-&&-CD27 receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0001618-&&-virus receptor activity	G:9606:SIVA1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway	SIVA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIVA1	0.38917162	0.10671937	23	4	FALSE	SIVA1	SIVA1	193.1304348	0	23	0	0.7384066	FALSE	0	SIVA1	56838	0.07027798
789774	taxon:9606	2.87726485	1.06E-04	174714	1902	lysophosphatidic acid receptor 6	gene	biological_process-&-1&-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0070915-&&-lysophosphatidic acid receptor activity	G:9606:LPAR6			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	LPAR6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPAR6	0.34755229	0.01581028	23	5	FALSE	LPAR6	LPAR6	52.13043478	0	23	0	0.68712253	FALSE	0	LPAR6	141306	0.0559209
789806	taxon:9606	2.81629116	3.53E-05	174618	1902	zinc metallopeptidase STE24	gene	biological_process-&-1&-GO:0071586-&&-CAAX-box protein processing-%%-GO:0006998-&&-nuclear envelope organization-%%-GO:0030327-&&-prenylated protein catabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005637-&&-nuclear inner membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008235-&&-metalloexopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ZMPSTE24			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis	ZMPSTE24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMPSTE24	0.35507692	0.06324111	23	4	FALSE	ZMPSTE24	ZMPSTE24	83.65217391	0	23	0	0.69728481	FALSE	0	ZMPSTE24	35278	0.06441099
789926	taxon:9606	2.73105404	3.01E-05	174343	1902	paraneoplastic Ma antigen 2	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PNMA2				PNMA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNMA2	0.36615899	0.03557312	23	4	FALSE	PNMA2	PNMA2	126.3913044	0	23	0	0.71149099	FALSE	0	PNMA2	39010	0.07055469
790001	taxon:9606	2.70521506	1.97E-05	174146	1902	zinc finger protein 510	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF510				ZNF510	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF510	0.36965638	0.10671937	23	4	FALSE	ZNF510	ZNF510	139.5217391	0	23	0	0.71579749	FALSE	0	ZNF510	38674	0.0712999
790024	taxon:9606	2.75846857	9.58E-06	174071	1902	ArfGAP with dual PH domains 1	gene	biological_process-&-1&-GO:0043087-&&-regulation of GTPase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043533-&&-inositol 1,3,4,5 tetrakisphosphate binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:ADAP1				ADAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAP1	0.36251999	0.06666667	23	4	FALSE	ADAP1	ADAP1	121.1428571	0	22	0	0.70692191	FALSE	1	ADAP1	16978	0.07386049
790039	taxon:9606	2.74680952	3.49E-05	174035	1902	stathmin 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0031117-&&-positive regulation of microtubule depolymerization|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0030027-&&-lamellipodium-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0030424-&&-axon-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0015631-&&-tubulin binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding	G:9606:STMN2				STMN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STMN2	0.36405874	0.04743083	23	4	FALSE	STMN2	STMN2	107.1304348	0	23	0	0.70886508	FALSE	0	STMN2	39956	0.06372485
790044	taxon:9606	2.70395462	4.85E-05	174017	1902	protease, serine 23	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity	G:9606:PRSS23				PRSS23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRSS23	0.36982869	0.02766798	23	4	FALSE	PRSS23	PRSS23	116.9565217	0	23	0	0.71600756	FALSE	0	PRSS23	48368	0.06054365
790066	taxon:9606	2.5838979	7.74E-06	173962	1902	nudix hydrolase 5	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0019303-&&-D-ribose catabolic process-%%-GO:0009191-&&-ribonucleoside diphosphate catabolic process-%%-GO:0009117-&&-nucleotide metabolic process-%%-GO:0034656-&&-nucleobase-containing small molecule catabolic process-%%-GO:1990966-&&-ATP generation from poly-ADP-D-ribose|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016779-&&-nucleotidyltransferase activity-%%-GO:0044715-&&-8-oxo-dGDP phosphatase activity-%%-GO:0050072-&&-m7G(5')pppN diphosphatase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0019144-&&-ADP-sugar diphosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0047631-&&-ADP-ribose diphosphatase activity-%%-GO:0030515-&&-snoRNA binding	G:9606:NUDT5			KEGG-&-1&-hsa00230-&&-Purine metabolism	NUDT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUDT5	0.3870122	0.13438735	23	4	FALSE	NUDT5	NUDT5	263.6086957	0	23	0	0.73601702	FALSE	0	NUDT5	26572	0.09787454
790183	taxon:9606	2.51867024	1.96E-05	173702	1902	PDS5 cohesin associated factor B	gene	biological_process-&-1&-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008283-&&-cell proliferation-%%-GO:0006281-&&-DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:PDS5B				PDS5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDS5B	0.39703491	0.27142857	23	4	FALSE	PDS5B	PDS5B	303.9047619	0	22	0	0.74688829	FALSE	1	PDS5B	42428	0.09833564
790193	taxon:9606	2.90137073	8.00E-07	173676	1902	lysine demethylase 4C	gene	biological_process-&-1&-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0001825-&&-blastocyst formation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:2000736-&&-regulation of stem cell differentiation|cellular_component-&-1&-GO:0005721-&&-pericentric heterochromatin-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0051213-&&-dioxygenase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0008270-&&-zinc ion binding	G:9606:KDM4C				KDM4C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM4C	0.34466468	0.48571429	23	4	FALSE	KDM4C	KDM4C	254.0476191	0	22	0	0.68310488	FALSE	1	KDM4C	5032	0.26940363
790206	taxon:9606	2.717977	4.82E-06	173636	1902	lysine demethylase 6B	gene	biological_process-&-1&-GO:0071557-&&-histone H3-K27 demethylation-%%-GO:0014823-&&-response to activity-%%-GO:0021766-&&-hippocampus development-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045446-&&-endothelial cell differentiation-%%-GO:0048333-&&-mesodermal cell differentiation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060992-&&-response to fungicide|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0071558-&&-histone demethylase activity (H3-K27 specific)	G:9606:KDM6B				KDM6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM6B	0.3679207	0.32411067	23	4	FALSE	KDM6B	KDM6B	279.4782609	0	23	0	0.7136705	FALSE	0	KDM6B	21456	0.14749093
790225	taxon:9606	2.72506696	3.21E-05	173594	1902	septin 8	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:SEPT8			KEGG-&-1&-hsa05100-&&-Bacterial invasion of epithelial cells	SEPT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT8	0.36696346	0.16666667	23	4	FALSE	SEPT8	SEPT8	121.4285714	0	22	0	0.71248884	FALSE	1	SEPT8	39432	0.06597195
790272	taxon:9606	2.73656846	1.48E-05	173465	1902	coactosin like F-actin binding protein 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0050832-&&-defense response to fungus-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:COTL1				COTL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COTL1	0.36542115	0.20158103	23	4	FALSE	COTL1	COTL1	144.3478261	0	23	0	0.71057192	FALSE	0	COTL1	22654	0.08097887
790279	taxon:9606	2.57728061	2.19E-05	173453	1902	NODAL modulator 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0003674-&&-molecular_function	G:9606:NOMO1				NOMO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOMO1	0.38800587	0.09881423	23	4	FALSE	NOMO1	NOMO1	206.7826087	0	23	0	0.7371199	FALSE	0	NOMO1	45936	0.07637638
790392	taxon:9606	2.65070112	3.25E-05	173128	1902	RAB GTPase activating protein 1	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0061024-&&-membrane organization-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0015631-&&-tubulin binding	G:9606:RABGAP1				RABGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABGAP1	0.37725868	0.07509881	23	4	FALSE	RABGAP1	RABGAP1	146.3043478	0	23	0	0.72488315	FALSE	0	RABGAP1	45168	0.06429803
790494	taxon:9606	2.54624232	1.27E-05	172700	1902	protein tyrosine phosphatase, non-receptor type 22	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0070433-&&-negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0050855-&&-regulation of B cell receptor signaling pathway-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:1903753-&&-negative regulation of p38MAPK cascade-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0071225-&&-cellular response to muramyl dipeptide-%%-GO:1902715-&&-positive regulation of interferon-gamma secretion-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:1902523-&&-positive regulation of protein K63-linked ubiquitination-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:1900165-&&-negative regulation of interleukin-6 secretion-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling-%%-GO:0050868-&&-negative regulation of T cell activation-%%-GO:0030217-&&-T cell differentiation-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0006914-&&-autophagy-%%-GO:0035644-&&-phosphoanandamide dephosphorylation-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:2000483-&&-negative regulation of interleukin-8 secretion-%%-GO:0032817-&&-regulation of natural killer cell proliferation-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0016791-&&-phosphatase activity-%%-GO:0019900-&&-kinase binding	G:9606:PTPN22				PTPN22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN22	0.3927356	0.25714286	23	4	FALSE	PTPN22	PTPN22	252.1428571	0	22	0	0.74229295	FALSE	1	PTPN22	35602	0.08666045
790511	taxon:9606	2.78525288	2.04E-05	172649	1902	3-hydroxyisobutyryl-CoA hydrolase	gene	biological_process-&-1&-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0006574-&&-valine catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0003860-&&-3-hydroxyisobutyryl-CoA hydrolase activity	G:9606:HIBCH			KEGG-&-1&-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism	HIBCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIBCH	0.35903383	0.06324111	23	4	FALSE	HIBCH	HIBCH	99.47826087	0	23	0	0.70245785	FALSE	0	HIBCH	26158	0.06663548
790512	taxon:9606	2.48983772	3.74E-05	172648	1902	VPS33B, late endosome and lysosome associated	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0032418-&&-lysosome localization-%%-GO:0090330-&&-regulation of platelet aggregation-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0061025-&&-membrane fusion-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0032400-&&-melanosome localization-%%-GO:0007032-&&-endosome organization-%%-GO:0070889-&&-platelet alpha granule organization|cellular_component-&-1&-GO:0031902-&&-late endosome membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0030897-&&-HOPS complex-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0030123-&&-AP-3 adaptor complex-%%-GO:0031091-&&-platelet alpha granule-%%-GO:0071439-&&-clathrin complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0055037-&&-recycling endosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:VPS33B				VPS33B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS33B	0.4016326	0.13833992	23	4	FALSE	VPS33B	VPS33B	253	0	23	0	0.75169371	FALSE	0	VPS33B	61228	0.07744565
790519	taxon:9606	2.69528911	6.80E-05	172642	1902	Era like 12S mitochondrial rRNA chaperone 1	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0000028-&&-ribosomal small subunit assembly|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding	G:9606:ERAL1				ERAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERAL1	0.37101771	0.11462451	23	4	FALSE	ERAL1	ERAL1	172.7391304	0	23	0	0.71745181	FALSE	0	ERAL1	71882	0.0844453
790539	taxon:9606	2.73199937	1.63E-05	172544	1902	UTP20, small subunit processome component	gene	biological_process-&-1&-GO:0000472-&&-endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000480-&&-endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000447-&&-endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0030688-&&-preribosome, small subunit precursor-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus-%%-GO:0030686-&&-90S preribosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:UTP20				UTP20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP20	0.3660323	0.18181818	23	4	FALSE	UTP20	UTP20	185.3478261	0	23	0	0.71133344	FALSE	0	UTP20	28158	0.10169613
790586	taxon:9606	2.7297936	2.39E-05	172071	1902	TATA-box binding protein associated factor 5 like	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0000932-&&-P-body-%%-GO:0016607-&&-nuclear speck-%%-GO:0033276-&&-transcription factor TFTC complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:TAF5L			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa03022-&&-Basal transcription factors	TAF5L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF5L	0.36632806	0.28853755	23	4	FALSE	TAF5L	TAF5L	130.4782609	0	23	0	0.71170107	FALSE	0	TAF5L	30196	0.07045828
790840	taxon:9606	2.5821648	1.19E-05	170998	1902	ribosomal RNA processing 15 homolog	gene	biological_process-&-1&-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0000470-&&-maturation of LSU-rRNA|cellular_component-&-1&-GO:0030687-&&-preribosome, large subunit precursor	G:9606:RRP15				RRP15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRP15	0.38727195	0.3201581	23	4	FALSE	RRP15	RRP15	258.8695652	0	23	0	0.73630587	FALSE	0	RRP15	28414	0.09605887
790935	taxon:9606	2.66850481	7.39E-06	170671	1902	peptidylprolyl isomerase like 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PPIL1			KEGG-&-1&-hsa03040-&&-Spliceosome	PPIL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIL1	0.37474169	0.2055336	23	4	FALSE	PPIL1	PPIL1	231	0	23	0	0.72191587	FALSE	0	PPIL1	20860	0.10513186
790959	taxon:9606	2.59035765	1.50E-05	170594	1902	tubulin alpha 8	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBA8			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa04530-&&-Tight junction	TUBA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA8	0.38604708	0.14624506	23	4	FALSE	TUBA8	TUBA8	217.6521739	0	23	0	0.73494039	FALSE	0	TUBA8	39892	0.08256578
791014	taxon:9606	2.64723491	3.22E-05	170387	1902	potassium channel tetramerization domain containing 9	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization|molecular_function-&-1&-GO:0097602-&&-cullin family protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KCTD9				KCTD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCTD9	0.37775265	0.08571429	23	4	FALSE	KCTD9	KCTD9	153.952381	0	22	0	0.72546085	FALSE	1	KCTD9	44488	0.06634194
791023	taxon:9606	2.74554908	1.79E-05	170329	1902	coiled-coil and C2 domain containing 1A	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CC2D1A				CC2D1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CC2D1A	0.36422587	0.22924901	23	4	FALSE	CC2D1A	CC2D1A	129.1304348	0	23	0	0.70907515	FALSE	0	CC2D1A	31910	0.07519331
791041	taxon:9606	2.76886718	1.20E-05	170271	1902	HAUS augmin like complex subunit 4	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0051225-&&-spindle assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0070652-&&-HAUS complex-%%-GO:0005813-&&-centrosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:HAUS4				HAUS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAUS4	0.36115853	0.36363636	23	4	FALSE	HAUS4	HAUS4	119.4782609	0	23	0	0.7051888	FALSE	0	HAUS4	20224	0.07436002
791149	taxon:9606	2.6615724	4.05E-05	169887	1902	proline rich nuclear receptor coactivator 2	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0031087-&&-deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PNRC2				PNRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNRC2	0.37571775	0.09090909	23	4	FALSE	PNRC2	PNRC2	147.826087	0	23	0	0.72307127	FALSE	0	PNRC2	52214	0.0670751
791195	taxon:9606	2.60957933	2.89E-05	169770	1902	exocyst complex component 2	gene	biological_process-&-1&-GO:0006893-&&-Golgi to plasma membrane transport-%%-GO:0015031-&&-protein transport-%%-GO:2000535-&&-regulation of entry of bacterium into host cell-%%-GO:0001927-&&-exocyst assembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0000145-&&-exocyst-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0017160-&&-Ral GTPase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:EXOC2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	EXOC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC2	0.38320353	0.28458498	23	4	FALSE	EXOC2	EXOC2	181.2608696	0	23	0	0.73173678	FALSE	0	EXOC2	39360	0.07178047
791208	taxon:9606	2.74239798	8.15E-06	169724	1902	DDB1 and CUL4 associated factor 6	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:DCAF6				DCAF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF6	0.36464438	0.10952381	23	4	FALSE	DCAF6	DCAF6	146.2380952	0	22	0	0.70960034	FALSE	1	DCAF6	18162	0.08442059
791209	taxon:9606	2.80478966	1.34E-05	169726	1902	phosphoprotein membrane anchor with glycosphingolipid microdomains 1	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050863-&&-regulation of T cell activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0050868-&&-negative regulation of T cell activation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042169-&&-SH2 domain binding	G:9606:PAG1				PAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAG1	0.35653297	0.33809524	23	4	FALSE	PAG1	PAG1	129.4761905	0	22	0	0.69920172	FALSE	1	PAG1	22332	0.09626559
791286	taxon:9606	2.69922798	2.42E-05	169336	1902	ubiquitin specific peptidase 36	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0016579-&&-protein deubiquitination-%%-GO:1903146-&&-regulation of mitophagy|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity	G:9606:USP36				USP36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP36	0.3704763	0.09881423	23	4	FALSE	USP36	USP36	148.6521739	0	23	0	0.71679534	FALSE	0	USP36	32012	0.0749451
791319	taxon:9606	2.80415945	3.02E-05	169195	1902	ankyrin repeat and MYND domain containing 2	gene	biological_process-&-1&-GO:0008589-&&-regulation of smoothened signaling pathway|cellular_component-&-1&-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:ANKMY2				ANKMY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKMY2	0.3566131	0.13043478	23	5	FALSE	ANKMY2	ANKMY2	88.60869565	0	23	0	0.69930676	FALSE	0	ANKMY2	28278	0.06373055
791371	taxon:9606	2.64755002	6.14E-06	168920	1902	nuclear receptor coactivator 5	gene	biological_process-&-1&-GO:0042593-&&-glucose homeostasis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:NCOA5				NCOA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA5	0.37770769	0.20952381	23	4	FALSE	NCOA5	NCOA5	242.0476191	0	22	0	0.72540833	FALSE	1	NCOA5	19134	0.10366426
791424	taxon:9606	2.69087758	1.30E-05	168699	1902	mitochondrial ribosomal protein L41	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0006412-&&-translation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:MRPL41				MRPL41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL41	0.37162597	0.23320158	23	4	FALSE	MRPL41	MRPL41	150.3043478	0	23	0	0.71818707	FALSE	0	MRPL41	26092	0.07280081
791499	taxon:9606	2.6866236	1.70E-05	168375	1902	MTOR associated protein, LST8 homolog	gene	biological_process-&-1&-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0031295-&&-T cell costimulation-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0016236-&&-macroautophagy-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031931-&&-TORC1 complex-%%-GO:0031932-&&-TORC2 complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0005515-&&-protein binding	G:9606:MLST8			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa04714-&&-Thermogenesis-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04136-&&-Autophagy - other	MLST8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLST8	0.3722144	0.09881423	23	4	FALSE	MLST8	MLST8	137.3913044	0	23	0	0.71889607	FALSE	0	MLST8	28546	0.06757568
791506	taxon:9606	2.63273988	3.15E-05	168354	1902	exportin 4	gene	biological_process-&-1&-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0006611-&&-protein export from nucleus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005049-&&-nuclear export signal receptor activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:XPO4				XPO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XPO4	0.37983244	0.08571429	23	4	FALSE	XPO4	XPO4	169.0952381	0	22	0	0.72787669	FALSE	1	XPO4	50136	0.07068047
791560	taxon:9606	2.84606901	2.96E-05	168043	1902	RIC3 acetylcholine receptor chaperone	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0034394-&&-protein localization to cell surface|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0033130-&&-acetylcholine receptor binding	G:9606:RIC3				RIC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIC3	0.35136182	0.07509881	23	4	FALSE	RIC3	RIC3	69.95652174	0	23	0	0.69232183	FALSE	0	RIC3	28760	0.06362769
791600	taxon:9606	2.88277927	5.23E-05	167871	1902	interactor of little elongation complex ELL subunit 2	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0042796-&&-snRNA transcription from RNA polymerase III promoter-%%-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0008023-&&-transcription elongation factor complex-%%-GO:0035363-&&-histone locus body-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ICE2				ICE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICE2	0.34688747	0.05928854	23	5	FALSE	ICE2	ICE2	55.65217391	0	23	0	0.68620346	FALSE	0	ICE2	51678	0.05576273
791606	taxon:9606	2.58846699	1.91E-05	167845	1902	solute carrier family 25 member 22	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0015992-&&-proton transport-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0015813-&&-L-glutamate transport-%%-GO:0089711-&&-L-glutamate transmembrane transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005280-&&-hydrogen:amino acid symporter activity-%%-GO:0005313-&&-L-glutamate transmembrane transporter activity-%%-GO:0005314-&&-high-affinity glutamate transmembrane transporter activity	G:9606:SLC25A22				SLC25A22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A22	0.38632905	0.07114625	23	4	FALSE	SLC25A22	SLC25A22	229.5217391	0	23	0	0.7352555	FALSE	0	SLC25A22	49120	0.08661146
791676	taxon:9606	2.67464944	2.08E-05	167478	1902	pseudouridylate synthase 1	gene	biological_process-&-1&-GO:0031119-&&-tRNA pseudouridine synthesis-%%-GO:0070902-&&-mitochondrial tRNA pseudouridine synthesis-%%-GO:1990481-&&-mRNA pseudouridine synthesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0009982-&&-pseudouridine synthase activity-%%-GO:0004730-&&-pseudouridylate synthase activity	G:9606:PUS1				PUS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PUS1	0.37388077	0.1027668	23	4	FALSE	PUS1	PUS1	134.6956522	0	23	0	0.72089176	FALSE	0	PUS1	31866	0.06303532
791679	taxon:9606	2.80620766	2.44E-05	167457	1902	tankyrase 2	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:1904357-&&-negative regulation of telomere maintenance via telomere lengthening-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0070213-&&-protein auto-ADP-ribosylation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0070198-&&-protein localization to chromosome, telomeric region-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0000242-&&-pericentriolar material-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0046872-&&-metal ion binding	G:9606:TNKS2				TNKS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNKS2	0.35635282	0.06190476	23	4	FALSE	TNKS2	TNKS2	84.33333333	0	22	0	0.69896539	FALSE	1	TNKS2	27634	0.06254654
791741	taxon:9606	2.65920908	1.89E-05	167098	1902	fermitin family member 3	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0033622-&&-integrin activation-%%-GO:0070527-&&-platelet aggregation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0033632-&&-regulation of cell-cell adhesion mediated by integrin-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0042995-&&-cell projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0002102-&&-podosome|molecular_function-&-1&-GO:0005178-&&-integrin binding	G:9606:FERMT3	FERMT3	TRUE	KEGG-&-1&-hsa04611-&&-Platelet activation	FERMT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FERMT3	0.37605166	0.08300395	23	4	FALSE	FERMT3	FERMT3	168.3478261	0	23	0	0.72346515	FALSE	0	FERMT3	35318	0.07588576
791743	taxon:9606	2.4376871	9.09E-06	167090	1902	RIO kinase 1	gene	biological_process-&-1&-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006364-&&-rRNA processing-%%-GO:2000234-&&-positive regulation of rRNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030688-&&-preribosome, small subunit precursor-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RIOK1			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	RIOK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIOK1	0.41022492	0.24901186	23	4	FALSE	RIOK1	RIOK1	360.3043478	0	23	0	0.76038548	FALSE	0	RIOK1	39374	0.09989031
791783	taxon:9606	2.60658579	2.55E-05	166887	1902	calcium/calmodulin dependent protein kinase kinase 1	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005515-&&-protein binding	G:9606:CAMKK1			KEGG-&-1&-hsa05034-&&-Alcoholism	CAMKK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMKK1	0.38364362	0.09881423	23	4	FALSE	CAMKK1	CAMKK1	198.2173913	0	23	0	0.7322357	FALSE	0	CAMKK1	45342	0.07797638
791784	taxon:9606	2.80825587	1.05E-05	166880	1902	proteasome assembly chaperone 3	gene	cellular_component-&-1&-GO:0000502-&&-proteasome complex	G:9606:PSMG3				PSMG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMG3	0.35609291	0.37549407	23	5	FALSE	PSMG3	PSMG3	108.7826087	0	23	0	0.69862402	FALSE	0	PSMG3	16036	0.08096733
791785	taxon:9606	2.66409327	2.58E-05	166883	1902	defective in cullin neddylation 1 domain containing 5	gene	biological_process-&-1&-GO:0045116-&&-protein neddylation-%%-GO:0008150-&&-biological_process-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0032182-&&-ubiquitin-like protein binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0097602-&&-cullin family protein binding-%%-GO:0005515-&&-protein binding	G:9606:DCUN1D5				DCUN1D5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCUN1D5	0.37536223	0.1541502	23	4	FALSE	DCUN1D5	DCUN1D5	203.7391304	0	23	0	0.72265112	FALSE	0	DCUN1D5	48788	0.0927285
791792	taxon:9606	2.64723491	3.92E-05	166849	1902	UTP23, small subunit processome component	gene	biological_process-&-1&-GO:0000480-&&-endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)|cellular_component-&-1&-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0070181-&&-small ribosomal subunit rRNA binding	G:9606:UTP23				UTP23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP23	0.37775265	0.14624506	23	5	FALSE	UTP23	UTP23	177.4347826	0	23	0	0.72546085	FALSE	0	UTP23	80866	0.07782933
791864	taxon:9606	2.61887506	2.61E-05	182963	1902	acyl-CoA dehydrogenase, very long chain	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0090181-&&-regulation of cholesterol metabolic process-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0015980-&&-energy derivation by oxidation of organic compounds-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0046322-&&-negative regulation of fatty acid oxidation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005730-&&-nucleolus-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003995-&&-acyl-CoA dehydrogenase activity-%%-GO:0004466-&&-long-chain-acyl-CoA dehydrogenase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:ACADVL			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	ACADVL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACADVL	0.38184334	0.05714286	23	4	FALSE	ACADVL	ACADVL	201.3333333	0	22	0	0.73018749	FALSE	1	ACADVL	48036	0.08058755
791866	taxon:9606	2.54655743	2.73E-05	166572	1902	UTP4, small subunit processome component	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034455-&&-t-UTP complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UTP4			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	UTP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP4	0.392687	0.14624506	23	4	FALSE	UTP4	UTP4	243.0434783	0	23	0	0.74224043	FALSE	0	UTP4	53260	0.08314734
791908	taxon:9606	2.67086813	1.17E-04	182894	1902	angiotensin II receptor type 1	gene	biological_process-&-1&-GO:0086097-&&-phospholipase C-activating angiotensin-activated signaling pathway-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0060326-&&-cell chemotaxis-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0035813-&&-regulation of renal sodium excretion-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0002034-&&-regulation of blood vessel diameter by renin-angiotensin-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0003081-&&-regulation of systemic arterial blood pressure by renin-angiotensin-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:0097746-&&-regulation of blood vessel diameter-%%-GO:0001822-&&-kidney development-%%-GO:0032430-&&-positive regulation of phospholipase A2 activity-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0002018-&&-renin-angiotensin regulation of aldosterone production-%%-GO:0010873-&&-positive regulation of cholesterol esterification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0001596-&&-angiotensin type I receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004945-&&-angiotensin type II receptor activity-%%-GO:0031711-&&-bradykinin receptor binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:AGTR1	AGTR1	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04614-&&-Renin-angiotensin system-%%-hsa04934-&&-Cushing syndrome-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	AGTR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGTR1	0.3744101	0.12252964	23	4	FALSE	AGTR1	AGTR1	142.173913	0	23	0	0.72152198	FALSE	0	AGTR1	121728	0.06719368
792412	taxon:9606	2.71545612	1.98E-05	182067	1902	colony stimulating factor 1 receptor	gene	biological_process-&-1&-GO:0031529-&&-ruffle organization-%%-GO:0045217-&&-cell-cell junction maintenance-%%-GO:0045087-&&-innate immune response-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0090197-&&-positive regulation of chemokine secretion-%%-GO:0007411-&&-axon guidance-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0021772-&&-olfactory bulb development-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0021879-&&-forebrain neuron differentiation-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0007275-&&-multicellular organism development-%%-GO:0030224-&&-monocyte differentiation-%%-GO:0036006-&&-cellular response to macrophage colony-stimulating factor stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0060603-&&-mammary gland duct morphogenesis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0038145-&&-macrophage colony-stimulating factor signaling pathway-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0007165-&&-signal transduction-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030097-&&-hemopoiesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009986-&&-cell surface-%%-GO:1990682-&&-CSF1-CSF1R complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005011-&&-macrophage colony-stimulating factor receptor activity-%%-GO:0019955-&&-cytokine binding-%%-GO:0005524-&&-ATP binding	G:9606:CSF1R			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CSF1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSF1R	0.36826226	0.32380952	23	5	FALSE	CSF1R	CSF1R	174.9047619	0	22	0	0.71409065	FALSE	1	CSF1R	26048	0.09345652
792429	taxon:9606	2.62202615	3.43E-05	182033	1902	cystatin A	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0070268-&&-cornification-%%-GO:0030216-&&-keratinocyte differentiation|cellular_component-&-1&-GO:0001533-&&-cornified envelope-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0030674-&&-protein binding, bridging	G:9606:CSTA				CSTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTA	0.38138445	0.07142857	23	4	FALSE	CSTA	CSTA	200.5714286	0	22	0	0.72966231	FALSE	1	CSTA	56724	0.08215508
792525	taxon:9606	2.73310225	9.14E-06	165465	1902	methyltransferase like 23	gene	biological_process-&-1&-GO:0032259-&&-methylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity	G:9606:METTL23				METTL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL23	0.36588459	0.07509881	23	4	FALSE	METTL23	METTL23	129.0434783	0	23	0	0.71114962	FALSE	0	METTL23	18720	0.07369155
792612	taxon:9606	2.78982196	1.72E-05	181720	1902	E2F transcription factor 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:1990086-&&-lens fiber cell apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001047-&&-core promoter binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding	G:9606:E2F2	E2F2	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05219-&&-Bladder cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04934-&&-Cushing syndrome-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	E2F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E2F2	0.35844581	0.11462451	23	5	FALSE	E2F2	E2F2	98.47826087	0	23	0	0.70169634	FALSE	0	E2F2	25654	0.06833162
792667	taxon:9606	2.7214432	4.15E-05	181595	1902	dachshund family transcription factor 1	gene	biological_process-&-1&-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0033262-&&-regulation of nuclear cell cycle DNA replication-%%-GO:0008283-&&-cell proliferation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0060244-&&-negative regulation of cell proliferation involved in contact inhibition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001967-&&-suckling behavior-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0046545-&&-development of primary female sexual characteristics-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0048147-&&-negative regulation of fibroblast proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:DACH1				DACH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DACH1	0.36745209	0.19047619	23	4	FALSE	DACH1	DACH1	170.3333333	0	22	0	0.7130928	FALSE	1	DACH1	47744	0.09159679
792702	taxon:9606	2.49629746	1.91E-05	181540	1902	2,4-dienoyl-CoA reductase 1	gene	biological_process-&-1&-GO:0051289-&&-protein homotetramerization-%%-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070402-&&-NADPH binding-%%-GO:0016651-&&-oxidoreductase activity, acting on NAD(P)H-%%-GO:0008670-&&-2,4-dienoyl-CoA reductase (NADPH) activity	G:9606:DECR1				DECR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DECR1	0.40059328	0.14285714	23	4	FALSE	DECR1	DECR1	322.1428571	0	22	0	0.75061709	FALSE	1	DECR1	50140	0.10012438
792885	taxon:9606	2.68615094	1.02E-05	164832	1902	zinc finger AN1-type containing 2B	gene	biological_process-&-1&-GO:0006616-&&-SRP-dependent cotranslational protein targeting to membrane, translocation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZFAND2B				ZFAND2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFAND2B	0.3722799	0.26190476	23	4	FALSE	ZFAND2B	ZFAND2B	175.4285714	0	22	0	0.71897484	FALSE	1	ZFAND2B	19292	0.08558873
792944	taxon:9606	2.84843233	4.45E-04	181107	1902	fibroblast activation protein alpha	gene	biological_process-&-1&-GO:0010710-&&-regulation of collagen catabolic process-%%-GO:1902362-&&-melanocyte apoptotic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0006508-&&-proteolysis-%%-GO:0097325-&&-melanocyte proliferation-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0010716-&&-negative regulation of extracellular matrix disassembly-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0060244-&&-negative regulation of cell proliferation involved in contact inhibition-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0007155-&&-cell adhesion-%%-GO:1903054-&&-negative regulation of extracellular matrix organization-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0051917-&&-regulation of fibrinolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045178-&&-basal part of cell-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0030027-&&-lamellipodium-%%-GO:0071438-&&-invadopodium membrane-%%-GO:0009986-&&-cell surface-%%-GO:0045177-&&-apical part of cell-%%-GO:0031258-&&-lamellipodium membrane|molecular_function-&-1&-GO:0046983-&&-protein dimerization activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0002020-&&-protease binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008239-&&-dipeptidyl-peptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005178-&&-integrin binding	G:9606:FAP				FAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAP	0.3510703	0.06190476	23	4	FALSE	FAP	FAP	70.66666667	0	22	0	0.69192794	FALSE	1	FAP	513054	0.06393939
793147	taxon:9606	2.74003466	4.19E-05	180640	1902	glutaminase	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0014047-&&-glutamate secretion-%%-GO:0002087-&&-regulation of respiratory gaseous exchange by neurological system process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0001967-&&-suckling behavior-%%-GO:0006537-&&-glutamate biosynthetic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006543-&&-glutamine catabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004359-&&-glutaminase activity-%%-GO:0005515-&&-protein binding	G:9606:GLS			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00471-&&-D-Glutamine and D-glutamate metabolism-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04727-&&-GABAergic synapse	GLS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLS	0.36495889	0.08695652	23	4	FALSE	GLS	GLS	110.5217391	0	23	0	0.70999422	FALSE	0	GLS	48442	0.06354901
793218	taxon:9606	2.66251772	1.13E-05	180512	1902	heat shock protein family A (Hsp70) member 7	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0008180-&&-COP9 signalosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function	G:9606:HSPA7				HSPA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA7	0.37558435	0.22134387	23	4	FALSE	HSPA7	HSPA7	264.6086957	0	23	0	0.72291371	FALSE	0	HSPA7	32584	0.12019763
793302	taxon:9606	2.64298094	4.58E-05	180350	1902	hemoglobin subunit zeta	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043249-&&-erythrocyte maturation|cellular_component-&-1&-GO:0005833-&&-hemoglobin complex-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding	G:9606:HBZ				HBZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBZ	0.37836066	0.12857143	23	5	FALSE	HBZ	HBZ	205.1428571	0	22	0	0.72616984	FALSE	1	HBZ	79912	0.08862377
793312	taxon:9606	2.72916338	3.01E-05	180328	1902	hexosaminidase subunit beta	gene	biological_process-&-1&-GO:0007040-&&-lysosome organization-%%-GO:0009313-&&-oligosaccharide catabolic process-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0008049-&&-male courtship behavior-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0008654-&&-phospholipid biosynthetic process-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0006689-&&-ganglioside catabolic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0048477-&&-oogenesis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001501-&&-skeletal system development-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0007626-&&-locomotory behavior-%%-GO:0042340-&&-keratan sulfate catabolic process-%%-GO:0007341-&&-penetration of zona pellucida-%%-GO:0019915-&&-lipid storage-%%-GO:0042552-&&-myelination-%%-GO:0030207-&&-chondroitin sulfate catabolic process|cellular_component-&-1&-GO:0042582-&&-azurophil granule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004563-&&-beta-N-acetylhexosaminidase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008375-&&-acetylglucosaminyltransferase activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:HEXB			KEGG-&-1&-hsa00604-&&-Glycosphingolipid biosynthesis - ganglio series-%%-hsa00603-&&-Glycosphingolipid biosynthesis - globo and isoglobo series-%%-hsa01100-&&-Metabolic pathways-%%-hsa00511-&&-Other glycan degradation-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa04142-&&-Lysosome-%%-hsa00531-&&-Glycosaminoglycan degradation	HEXB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEXB	0.36641265	0.11428571	23	4	FALSE	HEXB	HEXB	122.2380952	0	22	0	0.7118061	FALSE	1	HEXB	31926	0.06722843
787116	taxon:9606	2.83220419	1.10E-05	163651	1902	membrane bound O-acyltransferase domain containing 1	gene	biological_process-&-1&-GO:0036150-&&-phosphatidylserine acyl-chain remodeling-%%-GO:0036152-&&-phosphatidylethanolamine acyl-chain remodeling-%%-GO:0008654-&&-phospholipid biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0047144-&&-2-acylglycerol-3-phosphate O-acyltransferase activity-%%-GO:0003841-&&-1-acylglycerol-3-phosphate O-acyltransferase activity	G:9606:MBOAT1			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways	MBOAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MBOAT1	0.35308189	0.07359307	22	4	FALSE	MBOAT1	MBOAT1	81.95454545	0	22	0	0.69463263	FALSE	0	MBOAT1	16200	0.07135491
787197	taxon:9606	2.75909879	2.82E-05	179889	1902	MAGE family member A10	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm	G:9606:MAGEA10				MAGEA10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA10	0.36243719	0.04329004	22	4	FALSE	MAGEA10	MAGEA10	108.3636364	0	22	0	0.70681687	FALSE	0	MAGEA10	35118	0.06624254
787270	taxon:9606	2.69276824	6.90E-05	179774	1902	CD82 molecule	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CD82			KEGG-&-1&-hsa04115-&&-p53 signaling pathway	CD82	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD82	0.37136505	0.13852814	22	4	FALSE	CD82	CD82	144.9545455	0	22	0	0.71787196	FALSE	0	CD82	71646	0.07226456
787296	taxon:9606	2.61257287	4.28E-05	179713	1902	kinesin family member 5C	gene	biological_process-&-1&-GO:0006996-&&-organelle organization-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0051028-&&-mRNA transport-%%-GO:0007411-&&-axon guidance-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0008104-&&-protein localization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0035253-&&-ciliary rootlet-%%-GO:0005871-&&-kinesin complex-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003777-&&-microtubule motor activity-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:KIF5C			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04728-&&-Dopaminergic synapse	KIF5C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF5C	0.38276444	0.21645022	22	4	FALSE	KIF5C	KIF5C	190.9545455	0	22	0	0.73123786	FALSE	0	KIF5C	55092	0.0760716
787314	taxon:9606	2.65085867	6.02E-06	179679	1902	karyopherin subunit alpha 5	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0019054-&&-modulation by virus of host process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005643-&&-nuclear pore|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:KPNA5				KPNA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KPNA5	0.37723626	0.16017316	22	4	FALSE	KPNA5	KPNA5	199.5454546	0	22	0	0.72485689	FALSE	0	KPNA5	17014	0.08634593
787412	taxon:9606	2.82889554	2.01E-05	179478	1902	neutrophil cytosolic factor 2	gene	biological_process-&-1&-GO:0042554-&&-superoxide anion generation-%%-GO:0045087-&&-innate immune response-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045730-&&-respiratory burst-%%-GO:0006968-&&-cellular defense response-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0043020-&&-NADPH oxidase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0032010-&&-phagolysosome|molecular_function-&-1&-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0005515-&&-protein binding-%%-GO:0048365-&&-Rac GTPase binding	G:9606:NCF2			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation	NCF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCF2	0.35349485	0.17748918	22	4	FALSE	NCF2	NCF2	81.22727273	0	22	0	0.69518408	FALSE	0	NCF2	23370	0.06858526
787650	taxon:9606	2.48652907	4.84E-05	179009	1902	neurotrophic receptor tyrosine kinase 3	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0051412-&&-response to corticosterone-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0001764-&&-neuron migration-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007507-&&-heart development-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0042490-&&-mechanoreceptor differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0048691-&&-positive regulation of axon extension involved in regeneration-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0019056-&&-modulation by virus of host transcription-%%-GO:0045471-&&-response to ethanol-%%-GO:0007623-&&-circadian rhythm-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0048665-&&-neuron fate specification-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0048678-&&-response to axon injury-%%-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0090102-&&-cochlea development-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0038179-&&-neurotrophin signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0043121-&&-neurotrophin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0002039-&&-p53 binding-%%-GO:0005030-&&-neurotrophin receptor activity-%%-GO:0005524-&&-ATP binding	G:9606:NTRK3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer	NTRK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTRK3	0.40216703	0.18181818	22	4	FALSE	NTRK3	NTRK3	238.5454546	0	22	0	0.75224516	FALSE	0	NTRK3	62990	0.07261101
787683	taxon:9606	2.59492674	4.01E-05	178962	1902	phosphatidylinositol 4-kinase alpha	gene	biological_process-&-1&-GO:0044803-&&-multi-organism membrane organization-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0046786-&&-viral replication complex formation and maintenance-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0039694-&&-viral RNA genome replication-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0019034-&&-viral replication complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004430-&&-1-phosphatidylinositol 4-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0016301-&&-kinase activity	G:9606:PI4KA			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PI4KA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PI4KA	0.38536733	0.09090909	22	4	FALSE	PI4KA	PI4KA	243.9090909	0	22	0	0.73417888	FALSE	0	PI4KA	58388	0.09394173
787687	taxon:9606	2.66456594	3.10E-05	178944	1902	plakophilin 1	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0045110-&&-intermediate filament bundle assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0016337-&&-single organismal cell-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0030057-&&-desmosome-%%-GO:0005882-&&-intermediate filament-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0001533-&&-cornified envelope|molecular_function-&-1&-GO:0019215-&&-intermediate filament binding-%%-GO:0030280-&&-structural constituent of epidermis-%%-GO:0005521-&&-lamin binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:PKP1				PKP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKP1	0.37529565	0.12121212	22	4	FALSE	PKP1	PKP1	202.1363636	0	22	0	0.72257234	FALSE	0	PKP1	43400	0.09196521
787739	taxon:9606	2.58374035	1.50E-05	178852	1902	RNA polymerase II subunit K	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0050434-&&-positive regulation of viral transcription-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0010467-&&-gene expression-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005736-&&-DNA-directed RNA polymerase I complex|molecular_function-&-1&-GO:0001055-&&-RNA polymerase II activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001054-&&-RNA polymerase I activity	G:9606:POLR2K			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05016-&&-Huntington disease	POLR2K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR2K	0.38703579	0.64736842	22	4	FALSE	POLR2K	POLR2K	214.9	0	21	0	0.73604328	FALSE	1	POLR2K	28904	0.07979948
787759	taxon:9606	2.64093272	2.13E-05	162444	1902	copine 2	gene	biological_process-&-1&-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CPNE2				CPNE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPNE2	0.3786541	0.06060606	22	4	FALSE	CPNE2	CPNE2	170.1363636	0	22	0	0.72651121	FALSE	0	CPNE2	36392	0.07327265
787781	taxon:9606	2.76492831	3.02E-05	178798	1902	protein phosphatase 3 catalytic subunit beta	gene	biological_process-&-1&-GO:0034097-&&-response to cytokine-%%-GO:0035690-&&-cellular response to drug-%%-GO:0007507-&&-heart development-%%-GO:0007612-&&-learning-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007613-&&-memory-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0030217-&&-T cell differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0017156-&&-calcium ion regulated exocytosis-%%-GO:0042110-&&-T cell activation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0035176-&&-social behavior-%%-GO:0042098-&&-T cell proliferation-%%-GO:0031987-&&-locomotion involved in locomotory behavior-%%-GO:0001915-&&-negative regulation of T cell mediated cytotoxicity-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:0048675-&&-axon extension|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030315-&&-T-tubule-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005955-&&-calcineurin complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005516-&&-calmodulin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0008144-&&-drug binding-%%-GO:0033192-&&-calmodulin-dependent protein phosphatase activity	G:9606:PPP3CB			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3CB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3CB	0.36167303	0.05627706	22	4	FALSE	PPP3CB	PPP3CB	99.31818182	0	22	0	0.70584528	FALSE	0	PPP3CB	35782	0.06273764
787785	taxon:9606	2.80289901	2.33E-05	162410	1902	zinc finger and BTB domain containing 9	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB9				ZBTB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB9	0.35677347	0.08658009	22	4	FALSE	ZBTB9	ZBTB9	94.09090909	0	22	0	0.69951683	FALSE	0	ZBTB9	28720	0.06863137
787789	taxon:9606	2.59303608	3.12E-05	178785	1902	papillary renal cell carcinoma (translocation-associated)	gene	biological_process-&-1&-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PRCC			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05211-&&-Renal cell carcinoma	PRCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRCC	0.38564832	0.0995671	22	4	FALSE	PRCC	PRCC	195.2727273	0	22	0	0.73449399	FALSE	0	PRCC	49804	0.07379699
787840	taxon:9606	2.67102568	3.51E-05	178729	1902	mitogen-activated protein kinase kinase 5	gene	biological_process-&-1&-GO:0045415-&&-negative regulation of interleukin-8 biosynthetic process-%%-GO:0070375-&&-ERK5 cascade-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:2000342-&&-negative regulation of chemokine (C-X-C motif) ligand 2 production-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0060761-&&-negative regulation of response to cytokine stimulus-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005819-&&-spindle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:MAP2K5			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	MAP2K5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP2K5	0.37438801	0.18421053	22	4	FALSE	MAP2K5	MAP2K5	165.55	0	21	0	0.72149572	FALSE	1	MAP2K5	36596	0.07665739
788087	taxon:9606	2.70899638	2.31E-05	178261	1902	cyclin dependent kinase 14	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway-%%-GO:0051301-&&-cell division-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0000308-&&-cytoplasmic cyclin-dependent protein kinase holoenzyme complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030332-&&-cyclin binding	G:9606:CDK14			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	CDK14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK14	0.3691404	0.12631579	22	4	FALSE	CDK14	CDK14	171.25	0	21	0	0.71516727	FALSE	1	CDK14	31008	0.08778861
788143	taxon:9606	2.69907043	2.74E-05	178164	1902	quinoid dihydropteridine reductase	gene	biological_process-&-1&-GO:0035690-&&-cellular response to drug-%%-GO:0001889-&&-liver development-%%-GO:0010044-&&-response to aluminum ion-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006559-&&-L-phenylalanine catabolic process-%%-GO:0010288-&&-response to lead ion-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0033762-&&-response to glucagon-%%-GO:0051066-&&-dihydrobiopterin metabolic process-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0070402-&&-NADPH binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0070404-&&-NADH binding-%%-GO:0004155-&&-6,7-dihydropteridine reductase activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:QDPR			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	QDPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QDPR	0.37049793	0.12105263	22	4	FALSE	QDPR	QDPR	195.8	0	21	0	0.7168216	FALSE	1	QDPR	47932	0.09951654
788189	taxon:9606	2.51583425	1.66E-05	178104	1902	Ras protein specific guanine nucleotide releasing factor 1	gene	biological_process-&-1&-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:2000310-&&-regulation of NMDA receptor activity-%%-GO:0007165-&&-signal transduction-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0035020-&&-regulation of Rac protein signal transduction-%%-GO:0007616-&&-long-term memory-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0031175-&&-neuron projection development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0035254-&&-glutamate receptor binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:RASGRF1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway	RASGRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASGRF1	0.39748246	0.16883117	22	4	FALSE	RASGRF1	RASGRF1	240.1363636	0	22	0	0.74736096	FALSE	0	RASGRF1	35194	0.07751938
788329	taxon:9606	2.81314007	3.42E-05	161489	1902	dehydrogenase/reductase 4 like 2	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity	G:9606:DHRS4L2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00830-&&-Retinol metabolism	DHRS4L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHRS4L2	0.35547466	0.17894737	22	4	FALSE	DHRS4L2	DHRS4L2	83.1	0	21	0	0.69780999	FALSE	1	DHRS4L2	32754	0.06266968
788340	taxon:9606	2.8492201	2.68E-04	177841	1902	C-C motif chemokine ligand 2	gene	biological_process-&-1&-GO:2000502-&&-negative regulation of natural killer cell chemotaxis-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0000165-&&-MAPK cascade-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:1905237-&&-response to cyclosporin A-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0043200-&&-response to amino acid-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0046677-&&-response to antibiotic-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009408-&&-response to heat-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0035690-&&-cellular response to drug-%%-GO:0001912-&&-positive regulation of leukocyte mediated cytotoxicity-%%-GO:0036006-&&-cellular response to macrophage colony-stimulating factor stimulus-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009617-&&-response to bacterium-%%-GO:0035684-&&-helper T cell extravasation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0090265-&&-positive regulation of immune complex clearance by monocytes and macrophages-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0006959-&&-humoral immune response-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0006935-&&-chemotaxis-%%-GO:0007568-&&-aging-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0033552-&&-response to vitamin B3-%%-GO:0007155-&&-cell adhesion-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0002693-&&-positive regulation of cellular extravasation-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006954-&&-inflammatory response-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0010574-&&-regulation of vascular endothelial growth factor production-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0014823-&&-response to activity-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:0071398-&&-cellular response to fatty acid-%%-GO:0001525-&&-angiogenesis-%%-GO:2000427-&&-positive regulation of apoptotic cell clearance-%%-GO:0045471-&&-response to ethanol-%%-GO:0071403-&&-cellular response to high density lipoprotein particle stimulus-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0019079-&&-viral genome replication-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0032570-&&-response to progesterone-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0060137-&&-maternal process involved in parturition-%%-GO:0009611-&&-response to wounding-%%-GO:0010759-&&-positive regulation of macrophage chemotaxis-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005615-&&-extracellular space-%%-GO:0044299-&&-C-fiber-%%-GO:0005576-&&-extracellular region-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030425-&&-dendrite-%%-GO:0043204-&&-perikaryon-%%-GO:0043679-&&-axon terminus|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0031727-&&-CCR2 chemokine receptor binding	G:9606:CCL2	CCL2	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	CCL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL2	0.35097324	0.11578947	22	4	FALSE	CCL2	CCL2	83.85	0	21	0	0.69179665	FALSE	1	CCL2	379128	0.07260453
788411	taxon:9606	2.84937766	1.73E-05	177722	1902	syntaxin binding protein 2	gene	biological_process-&-1&-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0002576-&&-platelet degranulation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001909-&&-leukocyte mediated cytotoxicity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0042582-&&-azurophil granule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0044194-&&-cytolytic granule-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0042581-&&-specific granule-%%-GO:0042589-&&-zymogen granule membrane-%%-GO:0070820-&&-tertiary granule-%%-GO:0005576-&&-extracellular region-%%-GO:0031201-&&-SNARE complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017075-&&-syntaxin-1 binding-%%-GO:0030348-&&-syntaxin-3 binding	G:9606:STXBP2				STXBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STXBP2	0.35095383	0.17748918	22	4	FALSE	STXBP2	STXBP2	84.59090909	0	22	0	0.69177039	FALSE	0	STXBP2	20486	0.0748022
788525	taxon:9606	2.81676383	3.82E-05	177506	1902	secreted protein acidic and cysteine rich	gene	biological_process-&-1&-GO:0034097-&&-response to cytokine-%%-GO:0007507-&&-heart development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0048839-&&-inner ear development-%%-GO:0060348-&&-bone development-%%-GO:0007165-&&-signal transduction-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0010288-&&-response to lead ion-%%-GO:0051592-&&-response to calcium ion-%%-GO:0001503-&&-ossification-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0043473-&&-pigmentation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0045471-&&-response to ethanol-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0009629-&&-response to gravity-%%-GO:0030324-&&-lung development-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0042060-&&-wound healing-%%-GO:0051591-&&-response to cAMP-%%-GO:0033591-&&-response to L-ascorbic acid-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space-%%-GO:0005604-&&-basement membrane-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0005518-&&-collagen binding	G:9606:SPARC	SPARC	TRUE		SPARC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPARC	0.35501734	0.21052632	22	4	FALSE	SPARC	SPARC	84.1	0	21	0	0.69720603	FALSE	1	SPARC	35930	0.06501548
788559	taxon:9606	2.85520718	1.86E-05	144675	1902	PMF1-BGLAP readthrough	gene		G:9606:PMF1-BGLAP				PMF1-BGLAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMF1-BGLAP	0.35023728	0.08225108	22	5	FALSE	PMF1-BGLAP	PMF1-BGLAP	70.13636364	0	22	0	0.6907988	FALSE	0	PMF1-BGLAP	23676	0.06196512
788566	taxon:9606	2.73940444	1.08E-05	177420	1902	TATA-box binding protein associated factor 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006508-&&-proteolysis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0051123-&&-RNA polymerase II transcriptional preinitiation complex assembly-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0033276-&&-transcription factor TFTC complex|molecular_function-&-1&-GO:0001129-&&-RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001075-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TAF2			KEGG-&-1&-hsa03022-&&-Basal transcription factors	TAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF2	0.36504285	0.2987013	22	5	FALSE	TAF2	TAF2	140	0	22	0	0.71009926	FALSE	0	TAF2	22918	0.07872645
788958	taxon:9606	2.51756735	9.15E-06	176534	1902	PPFIA binding protein 1	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0045296-&&-cadherin binding	G:9606:PPFIBP1				PPFIBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPFIBP1	0.39720884	0.25789474	22	4	FALSE	PPFIBP1	PPFIBP1	315.8	0	21	0	0.74707211	FALSE	1	PPFIBP1	31734	0.10172414
788989	taxon:9606	2.72569718	2.35E-05	176451	1902	pyruvate dehydrogenase complex component X	gene	biological_process-&-1&-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0045254-&&-pyruvate dehydrogenase complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0034604-&&-pyruvate dehydrogenase (NAD+) activity-%%-GO:0016746-&&-transferase activity, transferring acyl groups	G:9606:PDHX			KEGG-&-1&-hsa01100-&&-Metabolic pathways	PDHX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDHX	0.36687861	0.18181818	22	4	FALSE	PDHX	PDHX	121.3181818	0	22	0	0.7123838	FALSE	0	PDHX	28920	0.06719915
789012	taxon:9606	2.68189696	1.08E-06	127233	1902	bolA-like protein 2	gene		G:9606:LOC107984053				LOC107984053	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC107984053	0.3728704	0.40692641	22	4	FALSE	LOC107984053	LOC107984053	386.6363636	0	22	0	0.71968384	FALSE	0	LOC107984053	12430	0.18117918
789052	taxon:9606	2.78399244	1.07E-05	176283	1902	fructose-bisphosphatase 2	gene	biological_process-&-1&-GO:0006094-&&-gluconeogenesis-%%-GO:0005986-&&-sucrose biosynthetic process-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006000-&&-fructose metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0042132-&&-fructose 1,6-bisphosphate 1-phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:FBP2			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00030-&&-Pentose phosphate pathway	FBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBP2	0.35919638	0.07368421	22	4	FALSE	FBP2	FBP2	119.2	0	21	0	0.70266793	FALSE	1	FBP2	22634	0.07977867
789117	taxon:9606	2.68189696	1.08E-06	127012	1902	BOLA2-SMG1P6 readthrough	gene		G:9606:BOLA2-SMG1P6				BOLA2-SMG1P6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BOLA2-SMG1P6	0.3728704	0.40692641	22	4	FALSE	BOLA2-SMG1P6	BOLA2-SMG1P6	386.6363636	0	22	0	0.71968384	FALSE	0	BOLA2-SMG1P6	12430	0.18117918
789342	taxon:9606	2.69371357	1.66E-05	175697	1902	PDZ and LIM domain 1	gene	biological_process-&-1&-GO:0001666-&&-response to hypoxia-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005913-&&-cell-cell adherens junction|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0098641-&&-cadherin binding involved in cell-cell adhesion-%%-GO:0003713-&&-transcription coactivator activity	G:9606:PDLIM1				PDLIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDLIM1	0.37123472	0.12631579	22	4	FALSE	PDLIM1	PDLIM1	156.2	0	21	0	0.71771441	FALSE	1	PDLIM1	25478	0.0770751
789428	taxon:9606	2.46904049	6.59E-05	175506	1902	sorting nexin 17	gene	biological_process-&-1&-GO:0003279-&&-cardiac septum development-%%-GO:0035904-&&-aorta development-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007165-&&-signal transduction-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0016197-&&-endosomal transport-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0006707-&&-cholesterol catabolic process-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0010008-&&-endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0005102-&&-receptor binding	G:9606:SNX17				SNX17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX17	0.40501563	0.25541126	22	4	FALSE	SNX17	SNX17	278.9090909	0	22	0	0.75515992	FALSE	0	SNX17	81900	0.08258586
789471	taxon:9606	2.57712305	2.27E-05	175388	1902	A-kinase anchoring protein 12	gene	biological_process-&-1&-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0090036-&&-regulation of protein kinase C signaling-%%-GO:0006605-&&-protein targeting-%%-GO:0010739-&&-positive regulation of protein kinase A signaling-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005925-&&-focal adhesion-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051018-&&-protein kinase A binding-%%-GO:0008179-&&-adenylate cyclase binding-%%-GO:0005515-&&-protein binding	G:9606:AKAP12				AKAP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP12	0.38802959	0.11688312	22	4	FALSE	AKAP12	AKAP12	191.8181818	0	22	0	0.73714616	FALSE	0	AKAP12	46780	0.07048046
789515	taxon:9606	2.67953364	1.62E-05	175298	1902	extra spindle pole bodies like 1, separase	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0045875-&&-negative regulation of sister chromatid cohesion-%%-GO:0045143-&&-homologous chromosome segregation-%%-GO:0045842-&&-positive regulation of mitotic metaphase/anaphase transition-%%-GO:0051307-&&-meiotic chromosome separation-%%-GO:0040001-&&-establishment of mitotic spindle localization-%%-GO:0000212-&&-meiotic spindle organization-%%-GO:0006508-&&-proteolysis-%%-GO:0000910-&&-cytokinesis|cellular_component-&-1&-GO:0072686-&&-mitotic spindle-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003824-&&-catalytic activity-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:ESPL1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection	ESPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESPL1	0.37319927	0.0952381	22	4	FALSE	ESPL1	ESPL1	154.1363636	0	22	0	0.72007773	FALSE	0	ESPL1	29116	0.0730897
789601	taxon:9606	2.84055459	9.80E-06	175090	1902	MAF bZIP transcription factor B	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007399-&&-nervous system development-%%-GO:0048538-&&-thymus development-%%-GO:0007379-&&-segment specification-%%-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0021571-&&-rhombomere 5 development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0021599-&&-abducens nerve formation-%%-GO:0021572-&&-rhombomere 6 development-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0007423-&&-sensory organ development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035284-&&-brain segmentation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:MAFB			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	MAFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAFB	0.35204393	0.17368421	22	4	FALSE	MAFB	MAFB	94.1	0	21	0	0.6932409	FALSE	1	MAFB	15150	0.07498005
789626	taxon:9606	2.83141642	1.74E-05	175034	1902	nuclear receptor subfamily 2 group E member 3	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0007602-&&-phototransduction-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045872-&&-positive regulation of rhodopsin gene expression-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0007601-&&-visual perception-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0060041-&&-retina development in camera-type eye|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:NR2E3				NR2E3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR2E3	0.35318012	0.25541126	22	5	FALSE	NR2E3	NR2E3	118.6818182	0	22	0	0.69476393	FALSE	0	NR2E3	22062	0.09341446
789701	taxon:9606	2.77154561	1.30E-05	174863	1902	DEAF1, transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008542-&&-visual learning-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033599-&&-regulation of mammary gland epithelial cell proliferation-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0001662-&&-behavioral fear response-%%-GO:0001843-&&-neural tube closure-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007281-&&-germ cell development|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:DEAF1				DEAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEAF1	0.3608095	0.05789474	22	4	FALSE	DEAF1	DEAF1	126.1	0	21	0	0.7047424	FALSE	1	DEAF1	22708	0.0801977
789766	taxon:9606	2.60485269	3.48E-05	174737	1902	RNA binding motif protein 12	gene	cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM12				RBM12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM12	0.38389887	0.11688312	22	4	FALSE	RBM12	RBM12	196.3636364	0	22	0	0.73252455	FALSE	0	RBM12	54882	0.07659144
789767	taxon:9606	2.6253348	5.50E-05	174739	1902	nicotinamide phosphoribosyltransferase	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0007165-&&-signal transduction-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0051770-&&-positive regulation of nitric-oxide synthase biosynthetic process-%%-GO:0007565-&&-female pregnancy-%%-GO:0007623-&&-circadian rhythm-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060612-&&-adipose tissue development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004514-&&-nicotinate-nucleotide diphosphorylase (carboxylating) activity-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0047280-&&-nicotinamide phosphoribosyltransferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005125-&&-cytokine activity	G:9606:NAMPT	NAMPT	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	NAMPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAMPT	0.3809038	0.15584416	22	4	FALSE	NAMPT	NAMPT	188.8181818	0	22	0	0.72911087	FALSE	0	NAMPT	69188	0.07729136
789822	taxon:9606	2.81314007	3.42E-05	174560	1902	dehydrogenase/reductase 4	gene	biological_process-&-1&-GO:0042180-&&-cellular ketone metabolic process-%%-GO:0042572-&&-retinol metabolic process-%%-GO:0006066-&&-alcohol metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0051262-&&-protein tetramerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0000253-&&-3-keto sterol reductase activity-%%-GO:0004090-&&-carbonyl reductase (NADPH) activity-%%-GO:0052650-&&-NADP-retinol dehydrogenase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0018455-&&-alcohol dehydrogenase [NAD(P)+] activity	G:9606:DHRS4			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa01100-&&-Metabolic pathways-%%-hsa00830-&&-Retinol metabolism	DHRS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHRS4	0.35547466	0.17894737	22	4	FALSE	DHRS4	DHRS4	83.1	0	21	0	0.69780999	FALSE	1	DHRS4	32754	0.06266968
789864	taxon:9606	2.5041752	7.12E-05	174484	1902	methionyl aminopeptidase 2	gene	biological_process-&-1&-GO:0018206-&&-peptidyl-methionine modification-%%-GO:0016485-&&-protein processing-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway-%%-GO:0031365-&&-N-terminal protein amino acid modification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008235-&&-metalloexopeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004177-&&-aminopeptidase activity	G:9606:METAP2				METAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METAP2	0.39933308	0.0952381	22	4	FALSE	METAP2	METAP2	238.0909091	0	22	0	0.74930413	FALSE	0	METAP2	80572	0.07509757
789937	taxon:9606	2.75153616	1.95E-05	174308	1902	retinoic acid induced 1	gene	biological_process-&-1&-GO:0001501-&&-skeletal system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0040015-&&-negative regulation of multicellular organism growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0005515-&&-protein binding	G:9606:RAI1				RAI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAI1	0.36343335	0.01731602	22	4	FALSE	RAI1	RAI1	142.0909091	0	22	0	0.70807731	FALSE	0	RAI1	32754	0.08335565
790013	taxon:9606	2.9004254	2.95E-05	157716	1902	mitotic spindle organizing protein 1	gene	biological_process-&-1&-GO:0090307-&&-mitotic spindle assembly-%%-GO:0033566-&&-gamma-tubulin complex localization-%%-GO:0051415-&&-interphase microtubule nucleation by interphase microtubule organizing center-%%-GO:0051417-&&-microtubule nucleation by spindle pole body|cellular_component-&-1&-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome-%%-GO:0000923-&&-equatorial microtubule organizing center-%%-GO:0031021-&&-interphase microtubule organizing center-%%-GO:0061495-&&-gamma-tubulin small complex, mitotic spindle pole body|molecular_function-&-1&-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:MZT1				MZT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MZT1	0.34477701	0.11688312	22	5	FALSE	MZT1	MZT1	60.59090909	0	22	0	0.68326243	FALSE	0	MZT1	29270	0.06984479
790031	taxon:9606	2.66519616	1.02E-05	174052	1902	DExD-box helicase 52	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing-%%-GO:0010501-&&-RNA secondary structure unwinding|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DDX52				DDX52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX52	0.3752069	0.22077922	22	4	FALSE	DDX52	DDX52	237.9545455	0	22	0	0.72246731	FALSE	0	DDX52	24698	0.10714578
790041	taxon:9606	2.6751221	3.46E-05	174031	1902	retention in endoplasmic reticulum sorting receptor 1	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0030173-&&-integral component of Golgi membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0033130-&&-acetylcholine receptor binding	G:9606:RER1				RER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RER1	0.37381471	0.15584416	22	4	FALSE	RER1	RER1	155.2272727	0	22	0	0.72081298	FALSE	0	RER1	52486	0.07231598
790118	taxon:9606	2.85520718	1.86E-05	173841	1902	polyamine modulated factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007059-&&-chromosome segregation-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000444-&&-MIS12/MIND type complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0005515-&&-protein binding	G:9606:PMF1				PMF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMF1	0.35023728	0.08225108	22	5	FALSE	PMF1	PMF1	70.13636364	0	22	0	0.6907988	FALSE	0	PMF1	23676	0.06196512
790207	taxon:9606	2.67732787	3.34E-05	173639	1902	G-patch domain containing 8	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:GPATCH8				GPATCH8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPATCH8	0.37350674	0.15151515	22	4	FALSE	GPATCH8	GPATCH8	162.1818182	0	22	0	0.72044535	FALSE	0	GPATCH8	41426	0.07633539
790208	taxon:9606	2.75657791	1.20E-05	173638	1902	RAD54-like 2 (S. cerevisiae)	gene	cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:RAD54L2				RAD54L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD54L2	0.36276863	0.14285714	22	4	FALSE	RAD54L2	RAD54L2	131.5	0	22	0	0.70723701	FALSE	0	RAD54L2	20752	0.08000221
790243	taxon:9606	2.81329762	3.65E-05	173533	1902	tripartite motif containing 2	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0043523-&&-regulation of neuron apoptotic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM2				TRIM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM2	0.35545475	0.05194805	22	5	FALSE	TRIM2	TRIM2	99.45454545	0	22	0	0.69778373	FALSE	0	TRIM2	34606	0.07597851
790245	taxon:9606	2.50842918	1.13E-04	173535	1902	DnaJ heat shock protein family (Hsp40) member C13	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:1902954-&&-regulation of early endosome to recycling endosome transport-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007032-&&-endosome organization-%%-GO:0015031-&&-protein transport-%%-GO:2000641-&&-regulation of early endosome to late endosome transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031901-&&-early endosome membrane-%%-GO:0071203-&&-WASH complex-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DNAJC13				DNAJC13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC13	0.39865586	0.12554113	22	4	FALSE	DNAJC13	DNAJC13	274.5	0	22	0	0.74859514	FALSE	0	DNAJC13	140890	0.08705628
790345	taxon:9606	2.71640145	3.98E-05	173267	1902	histone H4 transcription factor	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006281-&&-DNA repair-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045445-&&-myoblast differentiation|cellular_component-&-1&-GO:0015030-&&-Cajal body-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:HINFP				HINFP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HINFP	0.3681341	0.05627706	22	4	FALSE	HINFP	HINFP	125.8636364	0	22	0	0.71393309	FALSE	0	HINFP	36924	0.06605263
790407	taxon:9606	2.68189696	1.08E-06	156704	1902	bolA family member 2	gene	biological_process-&-1&-GO:0097428-&&-protein maturation by iron-sulfur cluster transfer-%%-GO:0044571-&&-[2Fe-2S] cluster assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BOLA2				BOLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BOLA2	0.3728704	0.40692641	22	4	FALSE	BOLA2	BOLA2	386.6363636	0	22	0	0.71968384	FALSE	0	BOLA2	12430	0.18117918
790438	taxon:9606	2.55443517	5.30E-05	172985	1902	transducin beta like 2	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0042149-&&-cellular response to glucose starvation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0031369-&&-translation initiation factor binding-%%-GO:0019901-&&-protein kinase binding	G:9606:TBL2				TBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBL2	0.39147598	0.0995671	22	4	FALSE	TBL2	TBL2	275.0909091	0	22	0	0.74092747	FALSE	0	TBL2	85132	0.095773
790542	taxon:9606	2.73908933	3.45E-05	172537	1902	serine/threonine kinase 39	gene	biological_process-&-1&-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0036438-&&-maintenance of lens transparency-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0090188-&&-negative regulation of pancreatic juice secretion-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0006950-&&-response to stress-%%-GO:2000687-&&-negative regulation of rubidium ion transmembrane transporter activity-%%-GO:0023016-&&-signal transduction by trans-phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:1905408-&&-negative regulation of creatine transmembrane transporter activity-%%-GO:0032414-&&-positive regulation of ion transmembrane transporter activity-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:2000021-&&-regulation of ion homeostasis-%%-GO:2000681-&&-negative regulation of rubidium ion transport-%%-GO:0071476-&&-cellular hypotonic response-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000650-&&-negative regulation of sodium ion transmembrane transporter activity-%%-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0001933-&&-negative regulation of protein phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding	G:9606:STK39				STK39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK39	0.36508484	0.05789474	22	4	FALSE	STK39	STK39	115.25	0	21	0	0.71015178	FALSE	1	STK39	39534	0.0664546
790577	taxon:9606	2.82275091	4.58E-05	172088	1902	dual adaptor of phosphotyrosine and 3-phosphoinositides 1	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding	G:9606:DAPP1			KEGG-&-1&-hsa04662-&&-B cell receptor signaling pathway	DAPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAPP1	0.35426434	0.08658009	22	5	FALSE	DAPP1	DAPP1	96.63636364	0	22	0	0.69620818	FALSE	0	DAPP1	52992	0.07785378
790668	taxon:9606	2.6883567	9.89E-06	171543	1902	MCTS1, re-initiation and release factor	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0002188-&&-translation reinitiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032790-&&-ribosome disassembly-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0002192-&&-IRES-dependent translational initiation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0005515-&&-protein binding	G:9606:MCTS1				MCTS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCTS1	0.37197445	0.15584416	22	4	FALSE	MCTS1	MCTS1	150	0	22	0	0.71860722	FALSE	0	MCTS1	20020	0.07248989
790688	taxon:9606	2.74996061	1.59E-05	171471	1902	ankyrin repeat domain 11	gene	biological_process-&-1&-GO:0001894-&&-tissue homeostasis-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060325-&&-face morphogenesis-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0060348-&&-bone development-%%-GO:0035264-&&-multicellular organism growth|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm	G:9606:ANKRD11				ANKRD11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD11	0.36364157	0.07792208	22	5	FALSE	ANKRD11	ANKRD11	128.6818182	0	22	0	0.7083399	FALSE	0	ANKRD11	25840	0.07582913
790704	taxon:9606	2.71104459	1.98E-05	171421	1902	PSMC3 interacting protein	gene	biological_process-&-1&-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0006310-&&-DNA recombination-%%-GO:0051321-&&-meiotic cell cycle|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity	G:9606:PSMC3IP				PSMC3IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSMC3IP	0.36886151	0.07368421	22	4	FALSE	PSMC3IP	PSMC3IP	155.5	0	21	0	0.7148259	FALSE	1	PSMC3IP	37636	0.08146982
790778	taxon:9606	2.68189696	1.08E-06	154853	1902	bolA family member 2B	gene	biological_process-&-1&-GO:0097428-&&-protein maturation by iron-sulfur cluster transfer-%%-GO:0044571-&&-[2Fe-2S] cluster assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BOLA2B				BOLA2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BOLA2B	0.3728704	0.40692641	22	4	FALSE	BOLA2B	BOLA2B	386.6363636	0	22	0	0.71968384	FALSE	0	BOLA2B	12430	0.18117918
790901	taxon:9606	2.65889397	2.12E-05	170733	1902	tRNA methyltransferase O	gene	biological_process-&-1&-GO:0030488-&&-tRNA methylation|molecular_function-&-1&-GO:0016430-&&-tRNA (adenine-N6-)-methyltransferase activity	G:9606:TRMO				TRMO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMO	0.37609623	0.06060606	22	4	FALSE	TRMO	TRMO	163.6363636	0	22	0	0.72351767	FALSE	0	TRMO	43644	0.07372506
790923	taxon:9606	2.6069009	3.01E-05	170693	1902	methyltransferase like 13	gene	biological_process-&-1&-GO:0032259-&&-methylation|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:METTL13				METTL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL13	0.38359724	0.11255411	22	4	FALSE	METTL13	METTL13	205.2272727	0	22	0	0.73218318	FALSE	0	METTL13	51400	0.08032501
790968	taxon:9606	2.56388845	2.43E-05	170566	1902	ubiquitin specific peptidase 47	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0034644-&&-cellular response to UV-%%-GO:0010972-&&-negative regulation of G2/M transition of mitotic cell cycle-%%-GO:0006284-&&-base-excision repair-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0035520-&&-monoubiquitinated protein deubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding-%%-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0071987-&&-WD40-repeat domain binding	G:9606:USP47				USP47	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP47	0.39003257	0.1038961	22	4	FALSE	USP47	USP47	228.0909091	0	22	0	0.73935192	FALSE	0	USP47	43854	0.08087619
790976	taxon:9606	2.7412951	1.70E-05	170539	1902	de-etiolated homolog 1 (Arabidopsis)	gene	cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:DET1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	DET1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DET1	0.36479108	0.24675325	22	4	FALSE	DET1	DET1	143.9090909	0	22	0	0.70978415	FALSE	0	DET1	25002	0.08167372
790978	taxon:9606	2.86718135	3.52E-05	170530	1902	intraflagellar transport 57	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0060972-&&-left/right pattern formation-%%-GO:0001947-&&-heart looping-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0042073-&&-intraciliary transport-%%-GO:0001843-&&-neural tube closure-%%-GO:0060271-&&-cilium assembly-%%-GO:0044458-&&-motile cilium assembly-%%-GO:1905515-&&-non-motile cilium assembly|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0005929-&&-cilium-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030992-&&-intraciliary transport particle B-%%-GO:0044292-&&-dendrite terminus-%%-GO:0005813-&&-centrosome-%%-GO:0097542-&&-ciliary tip-%%-GO:0032391-&&-photoreceptor connecting cilium|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:IFT57			KEGG-&-1&-hsa05016-&&-Huntington disease	IFT57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFT57	0.34877459	0.07368421	22	4	FALSE	IFT57	IFT57	69.15	0	21	0	0.68880311	FALSE	1	IFT57	29510	0.06721951
791002	taxon:9606	2.53930991	2.06E-05	170451	1902	mitochondrial rRNA methyltransferase 3	gene	biological_process-&-1&-GO:0000451-&&-rRNA 2'-O-methylation|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0070039-&&-rRNA (guanosine-2'-O-)-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:MRM3				MRM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRM3	0.39380778	0.1038961	22	4	FALSE	MRM3	MRM3	236.2272727	0	22	0	0.74344835	FALSE	0	MRM3	42140	0.07984136
791163	taxon:9606	2.52607531	3.26E-05	169844	1902	RAB, member RAS oncogene family-like 6	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:RABL6				RABL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABL6	0.39587102	0.11255411	22	4	FALSE	RABL6	RABL6	220.9545455	0	22	0	0.74565411	FALSE	0	RABL6	60006	0.072432
791172	taxon:9606	2.58972743	4.44E-05	169831	1902	MAP7 domain containing 1	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:MAP7D1				MAP7D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP7D1	0.38614102	0.07792208	22	4	FALSE	MAP7D1	MAP7D1	205.0909091	0	22	0	0.73504543	FALSE	0	MAP7D1	67320	0.07758977
791197	taxon:9606	2.51031984	1.49E-05	169761	1902	RIO kinase 2	gene	biological_process-&-1&-GO:2000234-&&-positive regulation of rRNA processing-%%-GO:0042274-&&-ribosomal small subunit biogenesis-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:2000208-&&-positive regulation of ribosomal small subunit export from nucleus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030688-&&-preribosome, small subunit precursor-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:RIOK2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	RIOK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIOK2	0.39835561	0.11255411	22	4	FALSE	RIOK2	RIOK2	245.7272727	0	22	0	0.74828003	FALSE	0	RIOK2	36002	0.07841743
791226	taxon:9606	2.75736568	1.23E-05	169664	1902	G protein subunit gamma 12	gene	biological_process-&-1&-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005884-&&-actin filament|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0042301-&&-phosphate ion binding	G:9606:GNG12			KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNG12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNG12	0.36266499	0.12121212	22	5	FALSE	GNG12	GNG12	116.8181818	0	22	0	0.70710572	FALSE	0	GNG12	21922	0.07165578
791255	taxon:9606	2.84118481	2.06E-05	169519	1902	neural proliferation, differentiation and control 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NPDC1				NPDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPDC1	0.35196584	0.18421053	22	5	FALSE	NPDC1	NPDC1	98.25	0	21	0	0.69313586	FALSE	1	NPDC1	28044	0.08295262
791296	taxon:9606	2.85772806	1.10E-05	169306	1902	myosin heavy chain 7B	gene	cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0097512-&&-cardiac myofibril-%%-GO:0032982-&&-myosin filament|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding	G:9606:MYH7B			KEGG-&-1&-hsa04530-&&-Tight junction	MYH7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH7B	0.34992833	0.0995671	22	5	FALSE	MYH7B	MYH7B	70.77272727	0	22	0	0.69037866	FALSE	0	MYH7B	13604	0.06722762
791300	taxon:9606	2.61729951	6.09E-05	169295	1902	calcium binding and coiled-coil domain 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0070016-&&-armadillo repeat domain binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003712-&&-transcription cofactor activity	G:9606:CALCOCO1				CALCOCO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALCOCO1	0.3820732	0.07359307	22	5	FALSE	CALCOCO1	CALCOCO1	174.1363636	0	22	0	0.73045008	FALSE	0	CALCOCO1	65252	0.07007805
791333	taxon:9606	2.70694816	1.80E-05	169114	1902	pellino E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0008063-&&-Toll signaling pathway-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0043331-&&-response to dsRNA|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PELI1				PELI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PELI1	0.36941971	0.16883117	22	4	FALSE	PELI1	PELI1	154.7272727	0	22	0	0.71550864	FALSE	0	PELI1	26674	0.08047418
791369	taxon:9606	2.60658579	1.27E-05	168943	1902	shootin 1	gene	biological_process-&-1&-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0060327-&&-cytoplasmic actin-based contraction involved in cell motility-%%-GO:0038007-&&-netrin-activated signaling pathway-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:0032488-&&-Cdc42 protein signal transduction-%%-GO:0061163-&&-endoplasmic reticulum polarization-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0061573-&&-actin filament bundle retrograde transport-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0007409-&&-axonogenesis-%%-GO:0045773-&&-positive regulation of axon extension|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0030424-&&-axon-%%-GO:0030175-&&-filopodium-%%-GO:0043204-&&-perikaryon-%%-GO:0005874-&&-microtubule-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031252-&&-cell leading edge-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0044295-&&-axonal growth cone-%%-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0019894-&&-kinesin binding	G:9606:SHTN1				SHTN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHTN1	0.38364362	0.14210526	22	4	FALSE	SHTN1	SHTN1	189.25	0	21	0	0.7322357	FALSE	1	SHTN1	22150	0.07439024
791409	taxon:9606	2.9038916	5.75E-05	168752	1902	purinergic receptor P2Y12	gene	biological_process-&-1&-GO:0010700-&&-negative regulation of norepinephrine secretion-%%-GO:0006930-&&-substrate-dependent cell migration, cell extension-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0070527-&&-platelet aggregation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:1904139-&&-regulation of microglial cell migration-%%-GO:0008347-&&-glial cell migration-%%-GO:0001973-&&-adenosine receptor signaling pathway-%%-GO:0007599-&&-hemostasis-%%-GO:0043270-&&-positive regulation of ion transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0035589-&&-G-protein coupled purinergic nucleotide receptor signaling pathway-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0031224-&&-intrinsic component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0005901-&&-caveola-%%-GO:0009925-&&-basal plasma membrane|molecular_function-&-1&-GO:0001621-&&-ADP receptor activity-%%-GO:0001609-&&-G-protein coupled adenosine receptor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:P2RY12			KEGG-&-1&-hsa04611-&&-Platelet activation	P2RY12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P2RY12	0.34436547	0.03463203	22	4	FALSE	P2RY12	P2RY12	49.45454545	0	22	0	0.68268473	FALSE	0	P2RY12	55194	0.06066239
791460	taxon:9606	2.72223098	2.81E-05	168553	1902	autophagy related 9A	gene	biological_process-&-1&-GO:0044805-&&-late nucleophagy-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0000422-&&-mitophagy-%%-GO:0015031-&&-protein transport-%%-GO:0034727-&&-piecemeal microautophagy of nucleus-%%-GO:0034497-&&-protein localization to pre-autophagosomal structure-%%-GO:0031667-&&-response to nutrient levels|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005770-&&-late endosome-%%-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0005776-&&-autophagosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0055037-&&-recycling endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ATG9A			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04137-&&-Mitophagy - animal-%%-hsa04136-&&-Autophagy - other	ATG9A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG9A	0.36734576	0.06926407	22	4	FALSE	ATG9A	ATG9A	127	0	22	0	0.7129615	FALSE	0	ATG9A	47502	0.0698454
791524	taxon:9606	2.54529699	8.96E-06	168258	1902	nucleolar protein 9	gene	biological_process-&-1&-GO:0000448-&&-cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0016310-&&-phosphorylation-%%-GO:0000460-&&-maturation of 5.8S rRNA-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0051731-&&-polynucleotide 5'-hydroxyl-kinase activity	G:9606:NOL9				NOL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOL9	0.39288146	0.2034632	22	4	FALSE	NOL9	NOL9	293.4090909	0	22	0	0.7424505	FALSE	0	NOL9	33166	0.0994453
791738	taxon:9606	2.75878368	2.24E-05	167112	1902	talin 2	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0007043-&&-cell-cell junction assembly|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0001726-&&-ruffle-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051015-&&-actin filament binding-%%-GO:0003779-&&-actin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:TLN2			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04611-&&-Platelet activation	TLN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLN2	0.36247858	0.04329004	22	4	FALSE	TLN2	TLN2	104.8181818	0	22	0	0.70686939	FALSE	0	TLN2	28232	0.06467774
791840	taxon:9606	2.74413109	1.14E-04	182988	1902	serpin family A member 3	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0030277-&&-maintenance of gastrointestinal epithelium-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006953-&&-acute-phase response-%%-GO:0002576-&&-platelet degranulation-%%-GO:0019216-&&-regulation of lipid metabolic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:SERPINA3	SERPINA3	TRUE		SERPINA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINA3	0.36441408	0.03157895	22	5	FALSE	SERPINA3	SERPINA3	102	0	21	0	0.70931149	FALSE	1	SERPINA3	76526	0.05974676
791842	taxon:9606	2.68788404	3.10E-05	182990	1902	N-acetyltransferase 2	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:1902475-&&-L-alpha-amino acid transmembrane transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015179-&&-L-amino acid transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0004060-&&-arylamine N-acetyltransferase activity	G:9606:NAT2			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00232-&&-Caffeine metabolism-%%-hsa05204-&&-Chemical carcinogenesis	NAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAT2	0.37203986	0.06493506	22	5	FALSE	NAT2	NAT2	135.5	0	22	0	0.71868599	FALSE	0	NAT2	44052	0.06557811
791911	taxon:9606	2.79250039	1.59E-05	166500	1902	ubiquitin specific peptidase 45	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0006281-&&-DNA repair-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0070911-&&-global genome nucleotide-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0008270-&&-zinc ion binding	G:9606:USP45				USP45	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP45	0.35810201	0.06060606	22	4	FALSE	USP45	USP45	105.0909091	0	22	0	0.70124993	FALSE	0	USP45	21714	0.07387567
792031	taxon:9606	2.53348038	1.02E-05	166325	1902	metadherin	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0046581-&&-intercellular canaliculus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0051059-&&-NF-kappaB binding-%%-GO:0003725-&&-double-stranded RNA binding	G:9606:MTDH				MTDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTDH	0.39471393	0.17748918	22	4	FALSE	MTDH	MTDH	289.1363636	0	22	0	0.74441994	FALSE	0	MTDH	34246	0.09634848
792086	taxon:9606	2.92043485	2.21E-04	182643	1902	C-C motif chemokine receptor 1	gene	biological_process-&-1&-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009611-&&-response to wounding-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006816-&&-calcium ion transport-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0006935-&&-chemotaxis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0006955-&&-immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0006887-&&-exocytosis-%%-GO:0045672-&&-positive regulation of osteoclast differentiation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0035717-&&-chemokine (C-C motif) ligand 7 binding-%%-GO:0005515-&&-protein binding-%%-GO:0016493-&&-C-C chemokine receptor activity-%%-GO:0071791-&&-chemokine (C-C motif) ligand 5 binding-%%-GO:0004950-&&-chemokine receptor activity-%%-GO:0019957-&&-C-C chemokine binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity	G:9606:CCR1			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	CCR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCR1	0.34241476	0.03684211	22	5	FALSE	CCR1	CCR1	52.2	0	21	0	0.67992752	FALSE	1	CCR1	348008	0.06947439
792125	taxon:9606	2.53221995	4.28E-05	166169	1902	kelch like family member 13	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000910-&&-cytokinesis|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL13			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	KLHL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL13	0.3949104	0.29437229	22	4	FALSE	KLHL13	KLHL13	266.8636364	0	22	0	0.74463001	FALSE	0	KLHL13	43916	0.08877628
792228	taxon:9606	2.84370569	4.91E-05	182377	1902	ATPase plasma membrane Ca2+ transporting 2	gene	biological_process-&-1&-GO:0006816-&&-calcium ion transport-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0021707-&&-cerebellar granule cell differentiation-%%-GO:0007595-&&-lactation-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0046068-&&-cGMP metabolic process-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0006996-&&-organelle organization-%%-GO:0042428-&&-serotonin metabolic process-%%-GO:0021702-&&-cerebellar Purkinje cell differentiation-%%-GO:0040011-&&-locomotion-%%-GO:0045299-&&-otolith mineralization-%%-GO:0007626-&&-locomotory behavior-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0090102-&&-cochlea development-%%-GO:0008361-&&-regulation of cell size-%%-GO:0006810-&&-transport-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0030182-&&-neuron differentiation-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0050808-&&-synapse organization-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005929-&&-cilium-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0030899-&&-calcium-dependent ATPase activity	G:9606:ATP2B2			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2B2	0.35165383	0.03896104	22	5	FALSE	ATP2B2	ATP2B2	69.54545455	0	22	0	0.69271572	FALSE	0	ATP2B2	41910	0.06031469
792324	taxon:9606	2.5835828	4.03E-05	165840	1902	myosin light chain 12B	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0008360-&&-regulation of cell shape|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005903-&&-brush border-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001725-&&-stress fiber-%%-GO:0016460-&&-myosin II complex-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0032036-&&-myosin heavy chain binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MYL12B			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction	MYL12B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL12B	0.3870594	0.13852814	22	4	FALSE	MYL12B	MYL12B	247.4545455	0	22	0	0.73606953	FALSE	0	MYL12B	71306	0.0918719
792414	taxon:9606	2.68898692	3.16E-05	182062	1902	colony stimulating factor 3 receptor	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0097186-&&-amelogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0045637-&&-regulation of myeloid cell differentiation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007155-&&-cell adhesion-%%-GO:0019221-&&-cytokine-mediated signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0051916-&&-granulocyte colony-stimulating factor binding-%%-GO:0004896-&&-cytokine receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:CSF3R			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CSF3R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSF3R	0.37188727	0.2	22	4	FALSE	CSF3R	CSF3R	165.95	0	21	0	0.71850218	FALSE	1	CSF3R	38960	0.08232373
792511	taxon:9606	2.79376083	1.49E-04	181883	1902	calcium voltage-gated channel auxiliary subunit alpha2delta 1	gene	biological_process-&-1&-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0061577-&&-calcium ion transmembrane transport via high voltage-gated calcium channel-%%-GO:0060402-&&-calcium ion transport into cytosol-%%-GO:0098703-&&-calcium ion import across plasma membrane-%%-GO:0006816-&&-calcium ion transport-%%-GO:0086048-&&-membrane depolarization during bundle of His cell action potential-%%-GO:0061337-&&-cardiac conduction-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0098903-&&-regulation of membrane repolarization during action potential-%%-GO:1901843-&&-positive regulation of high voltage-gated calcium channel activity-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:1990454-&&-L-type voltage-gated calcium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005891-&&-voltage-gated calcium channel complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0086007-&&-voltage-gated calcium channel activity involved in cardiac muscle cell action potential-%%-GO:0086057-&&-voltage-gated calcium channel activity involved in bundle of His cell action potential-%%-GO:0005245-&&-voltage-gated calcium channel activity	G:9606:CACNA2D1	CACNA2D1	TRUE	KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	CACNA2D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACNA2D1	0.35794045	0.01298701	22	4	FALSE	CACNA2D1	CACNA2D1	87.54545455	0	22	0	0.70103986	FALSE	0	CACNA2D1	158090	0.06059548
792527	taxon:9606	2.70978415	3.19E-05	181848	1902	capping actin protein, gelsolin like	gene	biological_process-&-1&-GO:0006461-&&-protein complex assembly-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0051016-&&-barbed-end actin filament capping-%%-GO:0071803-&&-positive regulation of podosome assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0090543-&&-Flemming body-%%-GO:0008290-&&-F-actin capping protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0042470-&&-melanosome-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CAPG				CAPG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPG	0.36903308	0.14285714	22	4	FALSE	CAPG	CAPG	136.4545455	0	22	0	0.71503598	FALSE	0	CAPG	42120	0.07078057
792570	taxon:9606	2.75531747	1.53E-05	181793	1902	cyclin D2	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007616-&&-long-term memory-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071481-&&-cellular response to X-ray-%%-GO:0007049-&&-cell cycle-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0008344-&&-adult locomotory behavior|cellular_component-&-1&-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0097129-&&-cyclin D2-CDK4 complex-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CCND2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa04110-&&-Cell cycle-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04218-&&-Cellular senescence	CCND2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCND2	0.36293458	0.18614719	22	4	FALSE	CCND2	CCND2	120.4545455	0	22	0	0.70744709	FALSE	0	CCND2	21534	0.07180461
792701	taxon:9606	2.58515834	2.33E-05	165157	1902	mitochondrial ribosomal protein L10	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0032543-&&-mitochondrial translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MRPL10			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL10	0.3868235	0.26315789	22	4	FALSE	MRPL10	MRPL10	229.85	0	21	0	0.73580694	FALSE	1	MRPL10	40136	0.08575429
792878	taxon:9606	2.71451079	1.39E-05	181239	1902	ETS variant 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007411-&&-axon guidance-%%-GO:0007517-&&-muscle organ development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007638-&&-mechanosensory behavior-%%-GO:0048935-&&-peripheral nervous system neuron development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ETV1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	ETV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETV1	0.3683905	0.19480519	22	5	FALSE	ETV1	ETV1	158.8181818	0	22	0	0.7142482	FALSE	0	ETV1	22990	0.08409572
793151	taxon:9606	2.67543721	5.12E-05	180633	1902	glutamate-ammonia ligase	gene	biological_process-&-1&-GO:0001504-&&-neurotransmitter uptake-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0019676-&&-ammonia assimilation cycle-%%-GO:0006538-&&-glutamate catabolic process-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0006542-&&-glutamine biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0009749-&&-response to glucose-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0032024-&&-positive regulation of insulin secretion|cellular_component-&-1&-GO:0097386-&&-glial cell projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath-%%-GO:0043679-&&-axon terminus-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon-%%-GO:0005829-&&-cytosol-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0016595-&&-glutamate binding-%%-GO:0005515-&&-protein binding-%%-GO:0004351-&&-glutamate decarboxylase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0045503-&&-dynein light chain binding-%%-GO:0004356-&&-glutamate-ammonia ligase activity-%%-GO:0042802-&&-identical protein binding	G:9606:GLUL	GLUL	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa00910-&&-Nitrogen metabolism-%%-hsa04727-&&-GABAergic synapse-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism-%%-hsa04217-&&-Necroptosis	GLUL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLUL	0.37377068	0.11578947	22	4	FALSE	GLUL	GLUL	162.65	0	21	0	0.72076046	FALSE	1	GLUL	59834	0.07721008
793247	taxon:9606	2.71781944	7.61E-06	180455	1902	interferon regulatory factor 8	gene	biological_process-&-1&-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0006909-&&-phagocytosis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071222-&&-cellular response to lipopolysaccharide|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	G:9606:IRF8			KEGG-&-1&-hsa05133-&&-Pertussis	IRF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF8	0.36794203	0.16842105	22	4	FALSE	IRF8	IRF8	159.05	0	21	0	0.71369676	FALSE	1	IRF8	17432	0.08504548
793264	taxon:9606	2.90247361	1.04E-04	164027	1902	coiled-coil domain containing 155	gene	biological_process-&-1&-GO:0051225-&&-spindle assembly-%%-GO:0048477-&&-oogenesis-%%-GO:0007283-&&-spermatogenesis-%%-GO:0090220-&&-chromosome localization to nuclear envelope involved in homologous chromosome segregation-%%-GO:0034397-&&-telomere localization-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0007129-&&-synapsis-%%-GO:0051653-&&-spindle localization-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0000800-&&-lateral element-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0034993-&&-LINC complex-%%-GO:0090619-&&-meiotic spindle pole-%%-GO:0000781-&&-chromosome, telomeric region|molecular_function-&-1&-GO:0070840-&&-dynein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CCDC155				CCDC155	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC155	0.34453371	0.00865801	22	4	FALSE	CCDC155	CCDC155	43	0	22	0	0.68292107	FALSE	0	CCDC155	110186	0.05144855
787087	taxon:9606	2.66346305	1.23E-04	180094	1902	immunoglobulin heavy constant mu	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0050871-&&-positive regulation of B cell activation-%%-GO:0006911-&&-phagocytosis, engulfment|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0071756-&&-pentameric IgM immunoglobulin complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0071757-&&-hexameric IgM immunoglobulin complex-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0034987-&&-immunoglobulin receptor binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0042834-&&-peptidoglycan binding-%%-GO:0003823-&&-antigen binding-%%-GO:0005515-&&-protein binding	G:9606:IGHM				IGHM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGHM	0.37545105	0.0994152	21	4	FALSE	IGHM	IGHM	168.6842105	0	20	0	0.72275616	FALSE	1	IGHM	152046	0.07772084
787161	taxon:9606	2.76335277	2.65E-05	179949	1902	LDL receptor related protein associated protein 1	gene	biological_process-&-1&-GO:1900222-&&-negative regulation of beta-amyloid clearance-%%-GO:0010916-&&-negative regulation of very-low-density lipoprotein particle clearance-%%-GO:0048259-&&-regulation of receptor-mediated endocytosis-%%-GO:1900116-&&-extracellular negative regulation of signal transduction-%%-GO:0032091-&&-negative regulation of protein binding|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048237-&&-rough endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0031904-&&-endosome lumen-%%-GO:0009986-&&-cell surface-%%-GO:0005801-&&-cis-Golgi network|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0048019-&&-receptor antagonist activity-%%-GO:0035473-&&-lipase binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0070326-&&-very-low-density lipoprotein particle receptor binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding	G:9606:LRPAP1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	LRPAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRPAP1	0.36187924	0.07619048	21	4	FALSE	LRPAP1	LRPAP1	114.5714286	0	21	0	0.70610787	FALSE	0	LRPAP1	34096	0.07151808
787338	taxon:9606	2.70616039	2.20E-05	179628	1902	laminin subunit alpha 4	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0045995-&&-regulation of embryonic development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005604-&&-basement membrane-%%-GO:0005605-&&-basal lamina|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding	G:9606:LAMA4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer	LAMA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMA4	0.36952725	0.07619048	21	4	FALSE	LAMA4	LAMA4	147.5238095	0	21	0	0.71563993	FALSE	0	LAMA4	35228	0.07643785
787341	taxon:9606	2.58925477	4.72E-05	179626	1902	laminin subunit beta 1	gene	biological_process-&-1&-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0021812-&&-neuronal-glial interaction involved in cerebral cortex radial glia guided migration-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0042476-&&-odontogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0043257-&&-laminin-8 complex-%%-GO:0005604-&&-basement membrane-%%-GO:0005606-&&-laminin-1 complex-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005607-&&-laminin-2 complex-%%-GO:0005615-&&-extracellular space-%%-GO:0043259-&&-laminin-10 complex|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:LAMB1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	LAMB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMB1	0.38621151	0.11904762	21	4	FALSE	LAMB1	LAMB1	196.952381	0	21	0	0.73512421	FALSE	0	LAMB1	63194	0.07452318
787455	taxon:9606	2.70694816	3.19E-05	179400	1902	mesenchyme homeobox 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0061056-&&-sclerotome development-%%-GO:0061053-&&-somite development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001757-&&-somite specification-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008150-&&-biological_process-%%-GO:0060218-&&-hematopoietic stem cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003674-&&-molecular_function	G:9606:MEOX1				MEOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEOX1	0.36941971	0.04761905	21	4	FALSE	MEOX1	MEOX1	118.1904762	0	21	0	0.71550864	FALSE	0	MEOX1	38522	0.06104816
787577	taxon:9606	2.88955412	1.23E-05	179151	1902	NADH:ubiquinone oxidoreductase subunit V3	gene	biological_process-&-1&-GO:0032981-&&-mitochondrial respiratory chain complex I assembly-%%-GO:0006120-&&-mitochondrial electron transport, NADH to ubiquinone|cellular_component-&-1&-GO:0005747-&&-mitochondrial respiratory chain complex I-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008137-&&-NADH dehydrogenase (ubiquinone) activity	G:9606:NDUFV3			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa04714-&&-Thermogenesis-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling	NDUFV3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDUFV3	0.34607415	0.34285714	21	4	FALSE	NDUFV3	NDUFV3	77.61904762	0	21	0	0.68507431	FALSE	0	NDUFV3	14420	0.08002167
787634	taxon:9606	2.79754215	1.70E-05	179053	1902	neuronal PAS domain protein 2	gene	biological_process-&-1&-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:2001020-&&-regulation of response to DNA damage stimulus-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007417-&&-central nervous system development-%%-GO:0051775-&&-response to redox state-%%-GO:0007623-&&-circadian rhythm|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:NPAS2			KEGG-&-1&-hsa04710-&&-Circadian rhythm	NPAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPAS2	0.35745663	0.22857143	21	4	FALSE	NPAS2	NPAS2	121.0476191	0	21	0	0.70040964	FALSE	0	NPAS2	24394	0.0845413
787658	taxon:9606	2.70348196	1.01E-04	179001	1902	nucleobindin 2	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NUCB2	NUCB2	TRUE		NUCB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUCB2	0.36989335	0.08095238	21	4	FALSE	NUCB2	NUCB2	132.4761905	0	21	0	0.71608634	FALSE	0	NUCB2	93934	0.06863472
787778	taxon:9606	2.71435324	6.30E-05	178797	1902	protein phosphatase 3 catalytic subunit gamma	gene	biological_process-&-1&-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007420-&&-brain development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:PPP3CC			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3CC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3CC	0.36841189	0.0952381	21	4	FALSE	PPP3CC	PPP3CC	115.6190476	0	21	0	0.71427446	FALSE	0	PPP3CC	55584	0.06140551
787973	taxon:9606	2.86781156	2.04E-04	178483	1902	serpin family A member 5	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0061107-&&-seminal vesicle development-%%-GO:0007596-&&-blood coagulation-%%-GO:0006869-&&-lipid transport-%%-GO:0007283-&&-spermatogenesis-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0007342-&&-fusion of sperm to egg plasma membrane|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0036026-&&-protein C inhibitor-PLAT complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0097181-&&-protein C inhibitor-coagulation factor V complex-%%-GO:0097182-&&-protein C inhibitor-coagulation factor Xa complex-%%-GO:0005576-&&-extracellular region-%%-GO:0031091-&&-platelet alpha granule-%%-GO:0097183-&&-protein C inhibitor-coagulation factor XI complex-%%-GO:0031094-&&-platelet dense tubular network-%%-GO:0005615-&&-extracellular space-%%-GO:0036027-&&-protein C inhibitor-PLAU complex-%%-GO:0036024-&&-protein C inhibitor-TMPRSS7 complex-%%-GO:0036029-&&-protein C inhibitor-KLK3 complex-%%-GO:0043234-&&-protein complex-%%-GO:0036028-&&-protein C inhibitor-thrombin complex-%%-GO:0016020-&&-membrane-%%-GO:0036025-&&-protein C inhibitor-TMPRSS11E complex-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0036030-&&-protein C inhibitor-plasma kallikrein complex|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0002020-&&-protease binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0005515-&&-protein binding-%%-GO:0032190-&&-acrosin binding-%%-GO:0008201-&&-heparin binding-%%-GO:0001972-&&-retinoic acid binding	G:9606:SERPINA5			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	SERPINA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINA5	0.34869795	0.0994152	21	4	FALSE	SERPINA5	SERPINA5	69.84210526	0	20	0	0.68869807	FALSE	1	SERPINA5	201566	0.06573982
787978	taxon:9606	2.75011817	2.13E-05	178475	1902	charged multivesicular body protein 1A	gene	biological_process-&-1&-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:0051301-&&-cell division-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1904903-&&-ESCRT III complex disassembly-%%-GO:0015031-&&-protein transport-%%-GO:0006508-&&-proteolysis-%%-GO:0045014-&&-negative regulation of transcription by glucose-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006997-&&-nucleus organization-%%-GO:0007034-&&-vacuolar transport-%%-GO:0007076-&&-mitotic chromosome condensation-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0016458-&&-gene silencing-%%-GO:0039702-&&-viral budding via host ESCRT complex|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000815-&&-ESCRT III complex-%%-GO:0005769-&&-early endosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016363-&&-nuclear matrix-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:CHMP1A			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	CHMP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHMP1A	0.36362074	0.1754386	21	5	FALSE	CHMP1A	CHMP1A	128.1052632	0	20	0	0.70831364	FALSE	1	CHMP1A	26488	0.07526316
787986	taxon:9606	2.78556798	5.45E-05	178450	1902	phosphodiesterase 6D	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0050896-&&-response to stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0004114-&&-3',5'-cyclic-nucleotide phosphodiesterase activity-%%-GO:0005515-&&-protein binding	G:9606:PDE6D			KEGG-&-1&-hsa00230-&&-Purine metabolism	PDE6D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE6D	0.35899321	0.02380952	21	4	FALSE	PDE6D	PDE6D	103.6666667	0	21	0	0.70240534	FALSE	0	PDE6D	49708	0.07132964
788146	taxon:9606	2.65826375	5.43E-05	178160	1902	RAB3A, member RAS oncogene family	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0061024-&&-membrane organization-%%-GO:0045054-&&-constitutive secretory pathway-%%-GO:0036465-&&-synaptic vesicle recycling-%%-GO:0015031-&&-protein transport-%%-GO:1903307-&&-positive regulation of regulated secretory pathway-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0016079-&&-synaptic vesicle exocytosis-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0048790-&&-maintenance of presynaptic active zone structure-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0061670-&&-evoked neurotransmitter secretion-%%-GO:0009791-&&-post-embryonic development-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0030324-&&-lung development-%%-GO:0031630-&&-regulation of synaptic vesicle fusion to presynaptic membrane-%%-GO:0007409-&&-axonogenesis-%%-GO:0016188-&&-synaptic vesicle maturation-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0048172-&&-regulation of short-term neuronal synaptic plasticity-%%-GO:0050975-&&-sensory perception of touch-%%-GO:0003016-&&-respiratory system process-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0070083-&&-clathrin-sculpted monoamine transport vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0060201-&&-clathrin-sculpted acetylcholine transport vesicle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0060203-&&-clathrin-sculpted glutamate transport vesicle membrane-%%-GO:0098993-&&-anchored component of synaptic vesicle membrane|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0051117-&&-ATPase binding	G:9606:RAB3A			KEGG-&-1&-hsa04911-&&-Insulin secretion-%%-hsa04721-&&-Synaptic vesicle cycle	RAB3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB3A	0.3761854	0.1754386	21	4	FALSE	RAB3A	RAB3A	158.631579	0	20	0	0.72362271	FALSE	1	RAB3A	56866	0.0711129
788184	taxon:9606	2.87411375	1.29E-05	178112	1902	retinoic acid receptor beta	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0003406-&&-retinal pigment epithelium development-%%-GO:0007165-&&-signal transduction-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0021756-&&-striatum development-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0031641-&&-regulation of myelination-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048384-&&-retinoic acid receptor signaling pathway-%%-GO:0001657-&&-ureteric bud development-%%-GO:0002068-&&-glandular epithelial cell development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0003417-&&-growth plate cartilage development-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0008144-&&-drug binding-%%-GO:0046965-&&-retinoid X receptor binding-%%-GO:0003708-&&-retinoic acid receptor activity-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0003677-&&-DNA binding	G:9606:RARB			KEGG-&-1&-hsa05223-&&-Non-small cell lung cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer-%%-hsa05222-&&-Small cell lung cancer	RARB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARB	0.34793334	0.12380952	21	4	FALSE	RARB	RARB	78.0952381	0	21	0	0.68764771	FALSE	0	RARB	15892	0.07705713
788457	taxon:9606	2.6681897	3.39E-05	177624	1902	solute carrier family 9 member A1	gene	biological_process-&-1&-GO:0016477-&&-cell migration-%%-GO:0086092-&&-regulation of the force of heart contraction by cardiac conduction-%%-GO:0070997-&&-neuron death-%%-GO:0006885-&&-regulation of pH-%%-GO:0045760-&&-positive regulation of action potential-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0071468-&&-cellular response to acidic pH-%%-GO:0086003-&&-cardiac muscle cell contraction-%%-GO:0016049-&&-cell growth-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0042493-&&-response to drug-%%-GO:0006811-&&-ion transport-%%-GO:0086036-&&-regulation of cardiac muscle cell membrane potential-%%-GO:0098735-&&-positive regulation of the force of heart contraction-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0098719-&&-sodium ion import across plasma membrane-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0071436-&&-sodium ion export-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:1903281-&&-positive regulation of calcium:sodium antiporter activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035794-&&-positive regulation of mitochondrial membrane permeability-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0071257-&&-cellular response to electrical stimulus-%%-GO:1902600-&&-hydrogen ion transmembrane transport-%%-GO:0030011-&&-maintenance of cell polarity-%%-GO:0051259-&&-protein oligomerization-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0010447-&&-response to acidic pH-%%-GO:0071260-&&-cellular response to mechanical stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0014704-&&-intercalated disc-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0090533-&&-cation-transporting ATPase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030315-&&-T-tubule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0030346-&&-protein phosphatase 2B binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0015385-&&-sodium:proton antiporter activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0015386-&&-potassium:proton antiporter activity-%%-GO:0015299-&&-solute:proton antiporter activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0086040-&&-sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential	G:9606:SLC9A1	SLC9A1	TRUE	KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04976-&&-Bile secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion	SLC9A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC9A1	0.37478595	0.1	21	4	FALSE	SLC9A1	SLC9A1	160.2380952	0	21	0	0.72196838	FALSE	0	SLC9A1	49074	0.07434673
788515	taxon:9606	2.73562313	9.34E-06	177520	1902	SRY-box 9	gene	biological_process-&-1&-GO:2000138-&&-positive regulation of cell proliferation involved in heart morphogenesis-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0030879-&&-mammary gland development-%%-GO:0071504-&&-cellular response to heparin-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008584-&&-male gonad development-%%-GO:0001894-&&-tissue homeostasis-%%-GO:0001502-&&-cartilage condensation-%%-GO:0003415-&&-chondrocyte hypertrophy-%%-GO:0003413-&&-chondrocyte differentiation involved in endochondral bone morphogenesis-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0060018-&&-astrocyte fate commitment-%%-GO:0030279-&&-negative regulation of ossification-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:2000741-&&-positive regulation of mesenchymal stem cell differentiation-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0006461-&&-protein complex assembly-%%-GO:0072289-&&-metanephric nephron tubule formation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0060784-&&-regulation of cell proliferation involved in tissue homeostasis-%%-GO:0061046-&&-regulation of branching involved in lung morphogenesis-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0060532-&&-bronchus cartilage development-%%-GO:2000794-&&-regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0072190-&&-ureter urothelium development-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0060729-&&-intestinal epithelial structure maintenance-%%-GO:0051216-&&-cartilage development-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0003170-&&-heart valve development-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:2001054-&&-negative regulation of mesenchymal cell apoptotic process-%%-GO:0003188-&&-heart valve formation-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0046533-&&-negative regulation of photoreceptor cell differentiation-%%-GO:0090184-&&-positive regulation of kidney development-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0072197-&&-ureter morphogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0002683-&&-negative regulation of immune system process-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0060008-&&-Sertoli cell differentiation-%%-GO:0001942-&&-hair follicle development-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0032808-&&-lacrimal gland development-%%-GO:0035622-&&-intrahepatic bile duct development-%%-GO:0030850-&&-prostate gland development-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0070168-&&-negative regulation of biomineral tissue development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030858-&&-positive regulation of epithelial cell differentiation-%%-GO:0060517-&&-epithelial cell proliferation involved in prostatic bud elongation-%%-GO:0030903-&&-notochord development-%%-GO:0072193-&&-ureter smooth muscle cell differentiation-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0061138-&&-morphogenesis of a branching epithelium-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0070384-&&-Harderian gland development-%%-GO:0060221-&&-retinal rod cell differentiation-%%-GO:0061145-&&-lung smooth muscle development-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0001503-&&-ossification-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0072034-&&-renal vesicle induction-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0001708-&&-cell fate specification-%%-GO:0007283-&&-spermatogenesis-%%-GO:0014032-&&-neural crest cell development-%%-GO:2000020-&&-positive regulation of male gonad development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060174-&&-limb bud formation-%%-GO:0001501-&&-skeletal system development-%%-GO:0060534-&&-trachea cartilage development-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0010564-&&-regulation of cell cycle process-%%-GO:0019100-&&-male germ-line sex determination-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0044798-&&-nuclear transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0035326-&&-enhancer binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:SOX9			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway	SOX9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX9	0.36554743	0.16374269	21	4	FALSE	SOX9	SOX9	174.0526316	0	20	0	0.71072948	FALSE	1	SOX9	17124	0.09953578
788516	taxon:9606	2.70915393	6.66E-05	177523	1902	SRY-box 4	gene	biological_process-&-1&-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0046826-&&-negative regulation of protein export from nucleus-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0003183-&&-mitral valve morphogenesis-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0060563-&&-neuroepithelial cell differentiation-%%-GO:0060993-&&-kidney morphogenesis-%%-GO:0001501-&&-skeletal system development-%%-GO:0060174-&&-limb bud formation-%%-GO:2000761-&&-positive regulation of N-terminal peptidyl-lysine acetylation-%%-GO:0003211-&&-cardiac ventricle formation-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030217-&&-T cell differentiation-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0021782-&&-glial cell development-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0001841-&&-neural tube formation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0021510-&&-spinal cord development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0050821-&&-protein stabilization-%%-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0007507-&&-heart development-%%-GO:0003357-&&-noradrenergic neuron differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0035910-&&-ascending aorta morphogenesis-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0044798-&&-nuclear transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0005515-&&-protein binding-%%-GO:0001071-&&-nucleic acid binding transcription factor activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding	G:9606:SOX4			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	SOX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX4	0.36911893	0.07142857	21	4	FALSE	SOX4	SOX4	147.1428571	0	21	0	0.71514101	FALSE	0	SOX4	66354	0.07664352
788760	taxon:9606	2.6218686	2.90E-05	176995	1902	zinc finger protein 148	gene	biological_process-&-1&-GO:0007276-&&-gamete generation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006461-&&-protein complex assembly-%%-GO:0021762-&&-substantia nigra development-%%-GO:0006968-&&-cellular defense response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZNF148				ZNF148	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF148	0.38140737	0.10952381	21	4	FALSE	ZNF148	ZNF148	197.4285714	0	21	0	0.72968857	FALSE	0	ZNF148	46124	0.08074365
788810	taxon:9606	2.67039546	5.13E-05	176830	1902	TYRO3 protein tyrosine kinase	gene	biological_process-&-1&-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0070527-&&-platelet aggregation-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0021885-&&-forebrain cell migration-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030168-&&-platelet activation-%%-GO:0070050-&&-neuron cellular homeostasis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042698-&&-ovulation cycle-%%-GO:0060068-&&-vagina development-%%-GO:0007165-&&-signal transduction-%%-GO:0007283-&&-spermatogenesis-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0051250-&&-negative regulation of lymphocyte activation-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0032940-&&-secretion by cell-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004716-&&-signal transducer, downstream of receptor, with protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:TYRO3				TYRO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYRO3	0.37447637	0.13809524	21	4	FALSE	TYRO3	TYRO3	162.952381	0	21	0	0.72160076	FALSE	0	TYRO3	67126	0.07622169
789089	taxon:9606	2.81282496	8.90E-06	176214	1902	synaptojanin 1	gene	biological_process-&-1&-GO:0048488-&&-synaptic vesicle endocytosis-%%-GO:0061024-&&-membrane organization-%%-GO:0006836-&&-neurotransmitter transport-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0046855-&&-inositol phosphate dephosphorylation-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:1904980-&&-positive regulation of endosome organization-%%-GO:0016191-&&-synaptic vesicle uncoating-%%-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0016082-&&-synaptic vesicle priming-%%-GO:0007612-&&-learning|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0005874-&&-microtubule-%%-GO:0030117-&&-membrane coat-%%-GO:0097060-&&-synaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0012506-&&-vesicle membrane-%%-GO:0098793-&&-presynapse-%%-GO:0030132-&&-clathrin coat of coated pit|molecular_function-&-1&-GO:0034596-&&-phosphatidylinositol phosphate 4-phosphatase activity-%%-GO:0052629-&&-phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity-%%-GO:0043813-&&-phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity-%%-GO:0034595-&&-phosphatidylinositol phosphate 5-phosphatase activity-%%-GO:0000166-&&-nucleotide binding-%%-GO:0004439-&&-phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0043812-&&-phosphatidylinositol-4-phosphate phosphatase activity-%%-GO:0004438-&&-phosphatidylinositol-3-phosphatase activity-%%-GO:0052658-&&-inositol-1,4,5-trisphosphate 5-phosphatase activity-%%-GO:0052659-&&-inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	G:9606:SYNJ1			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	SYNJ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNJ1	0.35551448	0.19047619	21	4	FALSE	SYNJ1	SYNJ1	105.7619048	0	21	0	0.69786251	FALSE	0	SYNJ1	16368	0.08033
789235	taxon:9606	2.70379707	2.28E-05	175937	1902	solute carrier family 25 member 12	gene	biological_process-&-1&-GO:0089712-&&-L-aspartate transmembrane transport-%%-GO:0043490-&&-malate-aspartate shuttle-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0015813-&&-L-glutamate transport-%%-GO:0051592-&&-response to calcium ion-%%-GO:0015810-&&-aspartate transport-%%-GO:0089711-&&-L-glutamate transmembrane transport|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0043209-&&-myelin sheath-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005313-&&-L-glutamate transmembrane transporter activity-%%-GO:0015172-&&-acidic amino acid transmembrane transporter activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0015183-&&-L-aspartate transmembrane transporter activity	G:9606:SLC25A12				SLC25A12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A12	0.36985024	0.09047619	21	4	FALSE	SLC25A12	SLC25A12	139.952381	0	21	0	0.71603382	FALSE	0	SLC25A12	38248	0.07195604
789249	taxon:9606	2.79328817	1.62E-05	175893	1902	aldehyde dehydrogenase 4 family member A1	gene	biological_process-&-1&-GO:0006562-&&-proline catabolic process-%%-GO:0006561-&&-proline biosynthetic process-%%-GO:0010133-&&-proline catabolic process to glutamate-%%-GO:0019470-&&-4-hydroxyproline catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006560-&&-proline metabolic process-%%-GO:0006537-&&-glutamate biosynthetic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0003842-&&-1-pyrroline-5-carboxylate dehydrogenase activity-%%-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0042802-&&-identical protein binding	G:9606:ALDH4A1			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	ALDH4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH4A1	0.35800102	0.21637427	21	4	FALSE	ALDH4A1	ALDH4A1	114	0	20	0	0.70111864	FALSE	1	ALDH4A1	20504	0.0786023
789272	taxon:9606	2.66976524	4.10E-06	175850	1902	tyrosine kinase non receptor 1	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:TNK1				TNK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNK1	0.37456477	0.29239766	21	4	FALSE	TNK1	TNK1	254	0	20	0	0.72170579	FALSE	1	TNK1	13302	0.11667432
789423	taxon:9606	2.74365842	1.32E-05	175519	1902	Ras association domain family member 2	gene	biological_process-&-1&-GO:0048872-&&-homeostasis of number of cells-%%-GO:0038168-&&-epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade-%%-GO:0050821-&&-protein stabilization-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:0001503-&&-ossification-%%-GO:0007049-&&-cell cycle-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0046849-&&-bone remodeling-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:RASSF2			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species	RASSF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASSF2	0.36447686	0.13809524	21	4	FALSE	RASSF2	RASSF2	163.2380952	0	21	0	0.70939026	FALSE	0	RASSF2	26028	0.09593879
789585	taxon:9606	2.5755475	1.38E-05	175130	1902	NUAK family kinase 1	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0035507-&&-regulation of myosin-light-chain-phosphatase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007155-&&-cell adhesion-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2000772-&&-regulation of cellular senescence|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:NUAK1				NUAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUAK1	0.38826696	0.18571429	21	4	FALSE	NUAK1	NUAK1	225.6190476	0	21	0	0.73740875	FALSE	0	NUAK1	26332	0.08200866
789639	taxon:9606	2.6152513	3.63E-05	174995	1902	high mobility group 20B	gene	biological_process-&-1&-GO:0016575-&&-histone deacetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0007049-&&-cell cycle-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004407-&&-histone deacetylase activity	G:9606:HMG20B				HMG20B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMG20B	0.38237243	0.18095238	21	4	FALSE	HMG20B	HMG20B	182.952381	0	21	0	0.73079145	FALSE	0	HMG20B	45514	0.07333945
789645	taxon:9606	2.83377974	1.41E-04	174986	1902	interferon regulatory factor 9	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001047-&&-core promoter binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:IRF9			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	IRF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF9	0.35288558	0.0994152	21	5	FALSE	IRF9	IRF9	93	0	20	0	0.69437004	FALSE	1	IRF9	224640	0.0766382
789851	taxon:9606	2.66283283	8.93E-05	174508	1902	lectin, mannose binding 2	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0015031-&&-protein transport-%%-GO:0050766-&&-positive regulation of phagocytosis|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005537-&&-mannose binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:LMAN2			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	LMAN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LMAN2	0.37553991	0.06666667	21	4	FALSE	LMAN2	LMAN2	194.952381	0	21	0	0.72286119	FALSE	0	LMAN2	98146	0.08762334
789871	taxon:9606	2.77217583	2.52E-05	174469	1902	interleukin 24	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0033136-&&-serine phosphorylation of STAT3 protein-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:IL24			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL24	0.36072748	0.06190476	21	4	FALSE	IL24	IL24	111.4285714	0	21	0	0.70463736	FALSE	0	IL24	37024	0.07375415
790016	taxon:9606	2.59776272	3.99E-06	174092	1902	protein phosphatase 1 regulatory subunit 13 like	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0009791-&&-post-embryonic development-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0042633-&&-hair cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0035264-&&-multicellular organism growth-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0003229-&&-ventricular cardiac muscle tissue development-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0048871-&&-multicellular organismal homeostasis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042802-&&-identical protein binding	G:9606:PPP1R13L				PPP1R13L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R13L	0.38494663	0.26315789	21	4	FALSE	PPP1R13L	PPP1R13L	267.4210526	0	20	0	0.73370621	FALSE	1	PPP1R13L	14710	0.10238062
790080	taxon:9606	2.66220262	2.08E-05	173920	1902	A-kinase anchoring protein 11	gene	biological_process-&-1&-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0051018-&&-protein kinase A binding	G:9606:AKAP11				AKAP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP11	0.37562881	0.19047619	21	4	FALSE	AKAP11	AKAP11	170.9047619	0	21	0	0.72296623	FALSE	0	AKAP11	33578	0.0770883
790114	taxon:9606	2.79817236	4.47E-05	173855	1902	phospholipase C beta 1	gene	biological_process-&-1&-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0060466-&&-activation of meiosis involved in egg activation-%%-GO:0007165-&&-signal transduction-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0080154-&&-regulation of fertilization-%%-GO:2000344-&&-positive regulation of acrosome reaction-%%-GO:0035722-&&-interleukin-12-mediated signaling pathway-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:2000560-&&-positive regulation of CD24 biosynthetic process-%%-GO:2000438-&&-negative regulation of monocyte extravasation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0007613-&&-memory-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0035723-&&-interleukin-15-mediated signaling pathway-%%-GO:0040019-&&-positive regulation of embryonic development-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0046488-&&-phosphatidylinositol metabolic process|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043209-&&-myelin sheath-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005521-&&-lamin binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0019899-&&-enzyme binding	G:9606:PLCB1	PLCB1	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04540-&&-Gap junction-%%-hsa04713-&&-Circadian entrainment-%%-hsa05016-&&-Huntington disease-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04970-&&-Salivary secretion	PLCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCB1	0.35737613	0.07017544	21	4	FALSE	PLCB1	PLCB1	102.5789474	0	20	0	0.70030461	FALSE	1	PLCB1	43014	0.07508308
790164	taxon:9606	2.60280447	2.73E-05	173728	1902	exosome component 7	gene	biological_process-&-1&-GO:0043488-&&-regulation of mRNA stability-%%-GO:0006401-&&-RNA catabolic process-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:EXOSC7			KEGG-&-1&-hsa03018-&&-RNA degradation	EXOSC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOSC7	0.38420097	0.27619048	21	4	FALSE	EXOSC7	EXOSC7	210.0476191	0	21	0	0.73286592	FALSE	0	EXOSC7	40846	0.08114374
790189	taxon:9606	2.76933985	2.05E-05	173681	1902	SWAP switching B-cell complex subunit 70	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0045190-&&-isotype switching-%%-GO:1902309-&&-negative regulation of peptidyl-serine dephosphorylation-%%-GO:0030835-&&-negative regulation of actin filament depolymerization-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0033633-&&-negative regulation of cell-cell adhesion mediated by integrin-%%-GO:0032233-&&-positive regulation of actin filament bundle assembly-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis-%%-GO:0051017-&&-actin filament bundle assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:SWAP70				SWAP70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SWAP70	0.36109689	0.17619048	21	5	FALSE	SWAP70	SWAP70	131.4761905	0	21	0	0.70511003	FALSE	0	SWAP70	25026	0.08265156
790222	taxon:9606	2.57570506	3.53E-05	173598	1902	family with sequence similarity 175 member B	gene	biological_process-&-1&-GO:0008608-&&-attachment of spindle microtubules to kinetochore-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0051301-&&-cell division-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007059-&&-chromosome segregation-%%-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0002931-&&-response to ischemia|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0031616-&&-spindle pole centrosome-%%-GO:0036449-&&-microtubule minus-end-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0070552-&&-BRISC complex|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0008017-&&-microtubule binding	G:9606:FAM175B				FAM175B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM175B	0.38824321	0.18095238	21	4	FALSE	FAM175B	FAM175B	210.3333333	0	21	0	0.73738249	FALSE	0	FAM175B	43720	0.07686279
790297	taxon:9606	2.67748543	1.81E-05	173394	1902	SAMM50 sorting and assembly machinery component	gene	biological_process-&-1&-GO:0042407-&&-cristae formation-%%-GO:0033108-&&-mitochondrial respiratory chain complex assembly-%%-GO:0045040-&&-protein import into mitochondrial outer membrane|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0001401-&&-mitochondrial sorting and assembly machinery complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SAMM50				SAMM50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAMM50	0.37348476	0.14285714	21	4	FALSE	SAMM50	SAMM50	164.4285714	0	21	0	0.7204191	FALSE	0	SAMM50	33076	0.07782364
790416	taxon:9606	2.59839294	3.06E-05	173059	1902	peptidylprolyl isomerase like 2	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050900-&&-leukocyte migration-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0072659-&&-protein localization to plasma membrane|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005796-&&-Golgi lumen|molecular_function-&-1&-GO:0034450-&&-ubiquitin-ubiquitin ligase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005515-&&-protein binding	G:9606:PPIL2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	PPIL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIL2	0.38485326	0.04678363	21	4	FALSE	PPIL2	PPIL2	212.7894737	0	20	0	0.73360118	FALSE	1	PPIL2	48932	0.08162852
790493	taxon:9606	2.66929258	1.55E-05	172701	1902	F-box and WD repeat domain containing 2	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXW2				FBXW2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXW2	0.37463109	0.18571429	21	4	FALSE	FBXW2	FBXW2	178.2857143	0	21	0	0.72178457	FALSE	0	FBXW2	27332	0.08222911
790500	taxon:9606	2.70442729	3.32E-05	172682	1902	F-box protein 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006516-&&-glycoprotein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	FBXO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO2	0.36976405	0.13333333	21	4	FALSE	FBXO2	FBXO2	165	0	21	0	0.71592879	FALSE	0	FBXO2	37558	0.08482219
790636	taxon:9606	2.61241531	3.23E-05	171699	1902	REV1, DNA directed polymerase	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006260-&&-DNA replication-%%-GO:0019985-&&-translesion synthesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0017125-&&-deoxycytidyl transferase activity-%%-GO:0005515-&&-protein binding	G:9606:REV1			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	REV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REV1	0.38278753	0.22807018	21	4	FALSE	REV1	REV1	210.0526316	0	20	0	0.73126411	FALSE	1	REV1	37352	0.08338731
790792	taxon:9606	2.8307862	3.02E-05	171191	1902	oxidative stress induced growth inhibitor 1	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding	G:9606:OSGIN1				OSGIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSGIN1	0.35325875	0.03333333	21	5	FALSE	OSGIN1	OSGIN1	79.85714286	0	21	0	0.69486897	FALSE	0	OSGIN1	29976	0.06780627
790796	taxon:9606	2.72475185	2.62E-05	171181	1902	nuclear receptor binding protein 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0030027-&&-lamellipodium-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:NRBP1				NRBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRBP1	0.3670059	0.10952381	21	4	FALSE	NRBP1	NRBP1	134.3809524	0	21	0	0.71254136	FALSE	0	NRBP1	36138	0.07253539
790802	taxon:9606	2.68347251	8.37E-06	171167	1902	glioma tumor suppressor candidate region gene 2	gene	biological_process-&-1&-GO:0000027-&&-ribosomal large subunit assembly-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008097-&&-5S rRNA binding	G:9606:GLTSCR2			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	GLTSCR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLTSCR2	0.37265148	0.2047619	21	4	FALSE	GLTSCR2	GLTSCR2	191.1904762	0	21	0	0.71942125	FALSE	0	GLTSCR2	17400	0.09121299
790841	taxon:9606	2.75059083	2.52E-05	170992	1902	fission, mitochondrial 1	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0014850-&&-response to muscle activity-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source-%%-GO:0016559-&&-peroxisome fission-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0097237-&&-cellular response to toxic substance-%%-GO:0008053-&&-mitochondrial fusion-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:0000266-&&-mitochondrial fission-%%-GO:0000422-&&-mitophagy-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0032471-&&-negative regulation of endoplasmic reticulum calcium ion concentration-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1905395-&&-response to flavonoid-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:1904579-&&-cellular response to thapsigargin-%%-GO:1990910-&&-response to hypobaric hypoxia|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005779-&&-integral component of peroxisomal membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0032403-&&-protein complex binding	G:9606:FIS1			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	FIS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FIS1	0.36355825	0.12865497	21	4	FALSE	FIS1	FIS1	126.6842105	0	20	0	0.70823486	FALSE	1	FIS1	31290	0.07685425
790941	taxon:9606	2.62880101	2.33E-05	170655	1902	negative regulator of ubiquitin like proteins 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NUB1				NUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUB1	0.38040156	0.24285714	21	4	FALSE	NUB1	NUB1	202.8095238	0	21	0	0.72853317	FALSE	0	NUB1	31880	0.08388991
791004	taxon:9606	2.63463053	2.36E-05	170443	1902	ubiquitin associated and SH3 domain containing A	gene	biological_process-&-1&-GO:0001817-&&-regulation of cytokine production-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UBASH3A				UBASH3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBASH3A	0.37955986	0.1754386	21	4	FALSE	UBASH3A	UBASH3A	198.1578947	0	20	0	0.72756158	FALSE	1	UBASH3A	30436	0.08334626
791089	taxon:9606	2.67008035	1.91E-05	170093	1902	elongator acetyltransferase complex subunit 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0046425-&&-regulation of JAK-STAT cascade|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0005829-&&-cytosol-%%-GO:0033588-&&-Elongator holoenzyme complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0008023-&&-transcription elongation factor complex|molecular_function-&-1&-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0019901-&&-protein kinase binding	G:9606:ELP2				ELP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELP2	0.37452056	0.15714286	21	4	FALSE	ELP2	ELP2	150.3333333	0	21	0	0.72165327	FALSE	0	ELP2	32380	0.06908486
791161	taxon:9606	2.72081298	1.30E-05	169859	1902	cell division cycle 37 like 1	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:0006457-&&-protein folding-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding	G:9606:CDC37L1				CDC37L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC37L1	0.36753721	0.24561404	21	4	FALSE	CDC37L1	CDC37L1	156.4736842	0	20	0	0.71319784	FALSE	1	CDC37L1	17436	0.08258767
791183	taxon:9606	2.82858043	3.32E-05	169799	1902	NAD(P)HX dehydratase	gene	biological_process-&-1&-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0047453-&&-ATP-dependent NAD(P)H-hydrate dehydratase activity-%%-GO:0003674-&&-molecular_function-%%-GO:0052855-&&-ADP-dependent NAD(P)H-hydrate dehydratase activity-%%-GO:0005515-&&-protein binding	G:9606:NAXD				NAXD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAXD	0.35353423	0.15238095	21	4	FALSE	NAXD	NAXD	99.28571429	0	21	0	0.69523659	FALSE	0	NAXD	44152	0.07658055
791292	taxon:9606	2.74413109	2.03E-05	169314	1902	SH3 domain containing ring finger 1	gene	biological_process-&-1&-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0046328-&&-regulation of JNK cascade|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity-%%-GO:0005515-&&-protein binding	G:9606:SH3RF1				SH3RF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3RF1	0.36441408	0.12280702	21	4	FALSE	SH3RF1	SH3RF1	139.9473684	0	20	0	0.70931149	FALSE	1	SH3RF1	25964	0.08214982
791322	taxon:9606	2.76414054	2.82E-06	169172	1902	PEST proteolytic signal containing nuclear protein	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0007049-&&-cell cycle-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PCNP				PCNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCNP	0.36177611	0.32857143	21	4	FALSE	PCNP	PCNP	289.3809524	0	21	0	0.70597658	FALSE	0	PCNP	14340	0.17793407
791419	taxon:9606	2.69008981	8.97E-06	168704	1902	mitochondrial ribosomal protein S15	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005763-&&-mitochondrial small ribosomal subunit-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome-%%-GO:0003723-&&-RNA binding	G:9606:MRPS15			KEGG-&-1&-hsa03010-&&-Ribosome	MRPS15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS15	0.3717348	0.28095238	21	4	FALSE	MRPS15	MRPS15	223.8095238	0	21	0	0.71831837	FALSE	0	MRPS15	23412	0.10815603
791641	taxon:9606	2.75972901	1.58E-05	167682	1902	jade family PHD finger 1	gene	biological_process-&-1&-GO:0043982-&&-histone H4-K8 acetylation-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0043981-&&-histone H4-K5 acetylation-%%-GO:0006915-&&-apoptotic process-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0043983-&&-histone H4-K12 acetylation-%%-GO:0006950-&&-response to stress-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043984-&&-histone H4-K16 acetylation-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0000123-&&-histone acetyltransferase complex-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding	G:9606:JADE1				JADE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JADE1	0.36235442	0.06666667	21	4	FALSE	JADE1	JADE1	129.7619048	0	21	0	0.70671183	FALSE	0	JADE1	25944	0.08022069
791656	taxon:9606	2.44698283	1.67E-05	167561	1902	tRNA methyltransferase 1 like	gene	biological_process-&-1&-GO:0030488-&&-tRNA methylation-%%-GO:0007610-&&-behavior|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004809-&&-tRNA (guanine-N2-)-methyltransferase activity-%%-GO:0000049-&&-tRNA binding	G:9606:TRMT1L				TRMT1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT1L	0.40866654	0.18095238	21	4	FALSE	TRMT1L	TRMT1L	359.0476191	0	21	0	0.7588362	FALSE	0	TRMT1L	45776	0.10183046
791658	taxon:9606	2.61320309	1.14E-05	167563	1902	diaphanous related formin 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0045296-&&-cadherin binding	G:9606:DIAPH3			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	DIAPH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIAPH3	0.38267213	0.13333333	21	4	FALSE	DIAPH3	DIAPH3	208.3809524	0	21	0	0.73113282	FALSE	0	DIAPH3	29356	0.08300568
791671	taxon:9606	2.82795021	2.68E-05	167493	1902	flavin adenine dinucleotide synthetase 1	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006747-&&-FAD biosynthetic process-%%-GO:0006771-&&-riboflavin metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003919-&&-FMN adenylyltransferase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:FLAD1			KEGG-&-1&-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways	FLAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLAD1	0.35361301	0.05847953	21	4	FALSE	FLAD1	FLAD1	105.8947368	0	20	0	0.69534163	FALSE	1	FLAD1	27224	0.08553164
791673	taxon:9606	2.77485426	1.61E-05	167487	1902	enhancer of polycomb homolog 1	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043968-&&-histone H2A acetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0035886-&&-vascular smooth muscle cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043967-&&-histone H4 acetylation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0032777-&&-Piccolo NuA4 histone acetyltransferase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035267-&&-NuA4 histone acetyltransferase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:EPC1				EPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPC1	0.36037929	0.34761905	21	4	FALSE	EPC1	EPC1	120.7142857	0	21	0	0.70419096	FALSE	0	EPC1	22064	0.07504146
791759	taxon:9606	2.7378289	9.24E-06	166994	1902	germ cell associated 2, haspin	gene	biological_process-&-1&-GO:0007064-&&-mitotic sister chromatid cohesion-%%-GO:0071459-&&-protein localization to chromosome, centromeric region-%%-GO:0090231-&&-regulation of spindle checkpoint-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:2000751-&&-histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005694-&&-chromosome-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0072354-&&-histone kinase activity (H3-T3 specific)-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:GSG2				GSG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSG2	0.36525292	0.33333333	21	4	FALSE	GSG2	GSG2	277.1428571	0	21	0	0.71036185	FALSE	0	GSG2	24548	0.15211422
791915	taxon:9606	2.62297148	2.10E-05	166497	1902	RALBP1 associated Eps domain containing 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005905-&&-clathrin-coated pit|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:REPS1				REPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REPS1	0.381247	0.1871345	21	4	FALSE	REPS1	REPS1	201.4210526	0	20	0	0.72950475	FALSE	1	REPS1	35546	0.08222743
791934	taxon:9606	2.67401922	2.91E-05	166461	1902	SH3 and multiple ankyrin repeat domains 3	gene	biological_process-&-1&-GO:1900451-&&-positive regulation of glutamate receptor signaling pathway-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0007416-&&-synapse assembly-%%-GO:0007612-&&-learning-%%-GO:2000969-&&-positive regulation of AMPA receptor activity-%%-GO:0097113-&&-AMPA glutamate receptor clustering-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0071625-&&-vocalization behavior-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0097114-&&-NMDA glutamate receptor clustering-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0051835-&&-positive regulation of synapse structural plasticity-%%-GO:0035176-&&-social behavior-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:1900452-&&-regulation of long term synaptic depression-%%-GO:0045794-&&-negative regulation of cell volume-%%-GO:0097117-&&-guanylate kinase-associated protein clustering-%%-GO:0042297-&&-vocal learning-%%-GO:1900271-&&-regulation of long-term synaptic potentiation-%%-GO:0030534-&&-adult behavior-%%-GO:0021773-&&-striatal medium spiny neuron differentiation-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0007613-&&-memory-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0000165-&&-MAPK cascade-%%-GO:0097107-&&-postsynaptic density assembly-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0048170-&&-positive regulation of long-term neuronal synaptic plasticity-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043197-&&-dendritic spine-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0060170-&&-ciliary membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043005-&&-neuron projection-%%-GO:0044309-&&-neuron spine|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0030160-&&-GKAP/Homer scaffold activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043621-&&-protein self-association	G:9606:SHANK3			KEGG-&-1&-hsa04724-&&-Glutamatergic synapse	SHANK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHANK3	0.37396889	0.25238095	21	4	FALSE	SHANK3	SHANK3	191.7619048	0	21	0	0.7209968	FALSE	0	SHANK3	37192	0.09079425
792007	taxon:9606	2.67953364	2.74E-05	166353	1902	WD repeat domain 20	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:WDR20				WDR20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR20	0.37319927	0.12380952	21	4	FALSE	WDR20	WDR20	147.3809524	0	21	0	0.72007773	FALSE	0	WDR20	38290	0.07017903
792091	taxon:9606	2.9237435	1.04E-04	166251	1902	Wnt family member 3A	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0070527-&&-platelet aggregation-%%-GO:0030879-&&-mammary gland development-%%-GO:0048697-&&-positive regulation of collateral sprouting in absence of injury-%%-GO:0034613-&&-cellular protein localization-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0099054-&&-presynapse assembly-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007411-&&-axon guidance-%%-GO:0048343-&&-paraxial mesodermal cell fate commitment-%%-GO:1904339-&&-negative regulation of dopaminergic neuron differentiation-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0021527-&&-spinal cord association neuron differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0061317-&&-canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment-%%-GO:0090245-&&-axis elongation involved in somitogenesis-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010387-&&-COP9 signalosome assembly-%%-GO:0030182-&&-neuron differentiation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0061184-&&-positive regulation of dermatome development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0001947-&&-heart looping-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0036342-&&-post-anal tail morphogenesis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0033278-&&-cell proliferation in midbrain-%%-GO:0021846-&&-cell proliferation in forebrain-%%-GO:0050768-&&-negative regulation of neurogenesis-%%-GO:1904953-&&-Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0021874-&&-Wnt signaling pathway involved in forebrain neuroblast division-%%-GO:0035413-&&-positive regulation of catenin import into nucleus-%%-GO:0060021-&&-palate development-%%-GO:0003136-&&-negative regulation of heart induction by canonical Wnt signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0048843-&&-negative regulation of axon extension involved in axon guidance-%%-GO:0048337-&&-positive regulation of mesodermal cell fate specification-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:2000081-&&-positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation-%%-GO:0030097-&&-hemopoiesis-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0021766-&&-hippocampus development-%%-GO:0090676-&&-calcium ion transmembrane transport via low voltage-gated calcium channel-%%-GO:0036465-&&-synaptic vesicle recycling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904798-&&-positive regulation of core promoter binding-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0048643-&&-positive regulation of skeletal muscle tissue development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0098793-&&-presynapse-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:1990851-&&-Wnt-Frizzled-LRP5/6 complex|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0039706-&&-co-receptor binding-%%-GO:0048018-&&-receptor agonist activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005110-&&-frizzled-2 binding	G:9606:WNT3A	WNT3A	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	WNT3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNT3A	0.34202727	0.0877193	21	5	FALSE	WNT3A	WNT3A	49.57894737	0	20	0	0.67937608	FALSE	1	WNT3A	108542	0.06909279
792188	taxon:9606	2.70852371	2.55E-04	166078	1902	dipeptidyl peptidase 9	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0042802-&&-identical protein binding	G:9606:DPP9				DPP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPP9	0.36920482	0.17142857	21	4	FALSE	DPP9	DPP9	121.1904762	0	21	0	0.71524605	FALSE	0	DPP9	237126	0.06254773
792250	taxon:9606	2.80368678	2.76E-05	182348	1902	ATPase H+ transporting accessory protein 1	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0051656-&&-establishment of organelle localization-%%-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:2001206-&&-positive regulation of osteoclast development-%%-GO:0033572-&&-transferrin transport-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0045851-&&-pH reduction-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0015992-&&-proton transport-%%-GO:0008286-&&-insulin receptor signaling pathway|cellular_component-&-1&-GO:0033180-&&-proton-transporting V-type ATPase, V1 domain-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016469-&&-proton-transporting two-sector ATPase complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046933-&&-proton-transporting ATP synthase activity, rotational mechanism-%%-GO:0005215-&&-transporter activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6AP1			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05161-&&-Hepatitis B-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05323-&&-Rheumatoid arthritis-%%-hsa05165-&&-Human papillomavirus infection	ATP6AP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6AP1	0.35667322	0.05238095	21	4	FALSE	ATP6AP1	ATP6AP1	103.7619048	0	21	0	0.69938554	FALSE	0	ATP6AP1	34062	0.07323411
792293	taxon:9606	2.75815346	9.88E-06	182276	1902	cyclin dependent kinase inhibitor 1C	gene	biological_process-&-1&-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042551-&&-neuron maturation-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0071514-&&-genetic imprinting-%%-GO:0055123-&&-digestive system development-%%-GO:0043010-&&-camera-type eye development-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0071901-&&-negative regulation of protein serine/threonine kinase activity-%%-GO:0001822-&&-kidney development-%%-GO:0007568-&&-aging-%%-GO:0060065-&&-uterus development-%%-GO:1902746-&&-regulation of lens fiber cell differentiation-%%-GO:0030325-&&-adrenal gland development-%%-GO:0001501-&&-skeletal system development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0060669-&&-embryonic placenta morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:CDKN1C	CDKN1C	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle	CDKN1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKN1C	0.36256141	0.30952381	21	5	FALSE	CDKN1C	CDKN1C	134.4285714	0	21	0	0.70697442	FALSE	0	CDKN1C	15714	0.0821822
792360	taxon:9606	2.69308335	8.07E-06	182162	1902	CDC28 protein kinase regulatory subunit 2	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007127-&&-meiosis I-%%-GO:0044772-&&-mitotic cell cycle phase transition-%%-GO:0008283-&&-cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051301-&&-cell division-%%-GO:0007346-&&-regulation of mitotic cell cycle|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000307-&&-cyclin-dependent protein kinase holoenzyme complex|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0042393-&&-histone binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0061575-&&-cyclin-dependent protein serine/threonine kinase activator activity-%%-GO:0043130-&&-ubiquitin binding	G:9606:CKS2			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05222-&&-Small cell lung cancer	CKS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CKS2	0.37132159	0.29239766	21	4	FALSE	CKS2	CKS2	174.1578947	0	20	0	0.71781944	FALSE	1	CKS2	16794	0.08639523
792393	taxon:9606	2.69229557	1.73E-05	165719	1902	ring finger and FYVE like domain containing E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:1901797-&&-negative regulation of signal transduction by p53 class mediator-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:2001271-&&-negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0002947-&&-tumor necrosis factor receptor superfamily complex-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0019901-&&-protein kinase binding	G:9606:RFFL				RFFL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFFL	0.37143024	0.15204678	21	4	FALSE	RFFL	RFFL	176.4736842	0	20	0	0.71795074	FALSE	1	RFFL	22984	0.08747551
792427	taxon:9606	2.47660312	1.65E-05	182043	1902	cysteine and glycine rich protein 1	gene	biological_process-&-1&-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CSRP1				CSRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSRP1	0.40377887	0.19883041	21	4	FALSE	CSRP1	CSRP1	324.4736842	0	20	0	0.75389948	FALSE	1	CSRP1	47982	0.09673976
792561	taxon:9606	2.85489207	1.13E-05	181815	1902	CBFA2/RUNX1 translocation partner 3	gene	biological_process-&-1&-GO:0030851-&&-granulocyte differentiation-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0008283-&&-cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:1903715-&&-regulation of aerobic respiration-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:CBFA2T3				CBFA2T3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBFA2T3	0.35027594	0.26315789	21	4	FALSE	CBFA2T3	CBFA2T3	109.2105263	0	20	0	0.69085132	FALSE	1	CBFA2T3	15122	0.09927685
792654	taxon:9606	2.71198992	6.54E-06	165248	1902	Jun dimerization protein 2	gene	biological_process-&-1&-GO:0031065-&&-positive regulation of histone deacetylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:JDP2				JDP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JDP2	0.36873293	0.30994152	21	4	FALSE	JDP2	JDP2	200.3684211	0	20	0	0.71466835	FALSE	1	JDP2	14098	0.10422258
792744	taxon:9606	2.72018276	1.79E-05	181453	1902	Fc fragment of IgG receptor IIb	gene	biological_process-&-1&-GO:0050776-&&-regulation of immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0006955-&&-immune response-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0019864-&&-IgG binding	G:9606:FCGR2B			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05150-&&-Staphylococcus aureus infection	FCGR2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCGR2B	0.36762236	0.27619048	21	5	FALSE	FCGR2B	FCGR2B	180.4285714	0	21	0	0.71330287	FALSE	0	FCGR2B	28122	0.09784771
792759	taxon:9606	2.77548448	3.33E-05	181427	1902	fibrinogen beta chain	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0072378-&&-blood coagulation, fibrin clot formation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0031639-&&-plasminogen activation-%%-GO:0043152-&&-induction of bacterial agglutination-%%-GO:0051592-&&-response to calcium ion-%%-GO:0007596-&&-blood coagulation-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0051258-&&-protein polymerization-%%-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:0042730-&&-fibrinolysis-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0070527-&&-platelet aggregation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0002250-&&-adaptive immune response|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005577-&&-fibrinogen complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:FGB			KEGG-&-1&-hsa04611-&&-Platelet activation-%%-hsa04610-&&-Complement and coagulation cascades	FGB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGB	0.36029746	0.10952381	21	4	FALSE	FGB	FGB	114.952381	0	21	0	0.70408592	FALSE	0	FGB	38736	0.07661008
792779	taxon:9606	2.87663463	5.80E-05	181387	1902	dopamine receptor D2	gene	biological_process-&-1&-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0031223-&&-auditory behavior-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic-%%-GO:0060134-&&-prepulse inhibition-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0051823-&&-regulation of synapse structural plasticity-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0001963-&&-synaptic transmission, dopaminergic-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0043473-&&-pigmentation-%%-GO:0042321-&&-negative regulation of circadian sleep/wake cycle, sleep-%%-GO:0043266-&&-regulation of potassium ion transport-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:1900168-&&-positive regulation of glial cell-derived neurotrophic factor secretion-%%-GO:0008104-&&-protein localization-%%-GO:0007626-&&-locomotory behavior-%%-GO:0042493-&&-response to drug-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0043666-&&-regulation of phosphoprotein phosphatase activity-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0008542-&&-visual learning-%%-GO:0021769-&&-orbitofrontal cortex development-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0043278-&&-response to morphine-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0007625-&&-grooming behavior-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0021853-&&-cerebral cortex GABAergic interneuron migration-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0008306-&&-associative learning-%%-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0050709-&&-negative regulation of protein secretion-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0090325-&&-regulation of locomotion involved in locomotory behavior-%%-GO:0007409-&&-axonogenesis-%%-GO:0051481-&&-negative regulation of cytosolic calcium ion concentration-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0010039-&&-response to iron ion-%%-GO:0051584-&&-regulation of dopamine uptake involved in synaptic transmission-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0033602-&&-negative regulation of dopamine secretion-%%-GO:0048678-&&-response to axon injury-%%-GO:0030814-&&-regulation of cAMP metabolic process-%%-GO:0051586-&&-positive regulation of dopamine uptake involved in synaptic transmission-%%-GO:0001975-&&-response to amphetamine-%%-GO:0034776-&&-response to histamine-%%-GO:0035094-&&-response to nicotine-%%-GO:0042220-&&-response to cocaine-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0048755-&&-branching morphogenesis of a nerve-%%-GO:0009416-&&-response to light stimulus-%%-GO:0007195-&&-adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0007416-&&-synapse assembly-%%-GO:0051967-&&-negative regulation of synaptic transmission, glutamatergic-%%-GO:0007616-&&-long-term memory-%%-GO:0021756-&&-striatum development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0007631-&&-feeding behavior-%%-GO:0001976-&&-neurological system process involved in regulation of systemic arterial blood pressure-%%-GO:0014854-&&-response to inactivity-%%-GO:0060160-&&-negative regulation of dopamine receptor signaling pathway-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0030432-&&-peristalsis-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0007628-&&-adult walking behavior-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:1901386-&&-negative regulation of voltage-gated calcium channel activity-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0007270-&&-neuron-neuron synaptic transmission-%%-GO:0030336-&&-negative regulation of cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043197-&&-dendritic spine-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0060170-&&-ciliary membrane-%%-GO:0036126-&&-sperm flagellum-%%-GO:0097730-&&-non-motile cilium-%%-GO:0030424-&&-axon-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0043204-&&-perikaryon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043679-&&-axon terminus-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035240-&&-dopamine binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004935-&&-adrenergic receptor activity-%%-GO:0001591-&&-dopamine neurotransmitter receptor activity, coupled via Gi/Go-%%-GO:0008144-&&-drug binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:DRD2	DRD2	TRUE	KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa05034-&&-Alcoholism-%%-hsa05030-&&-Cocaine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	DRD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DRD2	0.34762844	0.04678363	21	5	FALSE	DRD2	DRD2	64	0	20	0	0.68722756	FALSE	1	DRD2	86650	0.06671453
793017	taxon:9606	2.74507641	4.87E-05	180891	1902	G protein-coupled receptor kinase 6	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0005515-&&-protein binding	G:9606:GRK6			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway	GRK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK6	0.36428858	0.02339181	21	4	FALSE	GRK6	GRK6	117.631579	0	20	0	0.70915393	FALSE	1	GRK6	46484	0.06838106
793146	taxon:9606	2.67890342	1.76E-05	180647	1902	GLI family zinc finger 3	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0043585-&&-nose morphogenesis-%%-GO:1903010-&&-regulation of bone development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0021775-&&-smoothened signaling pathway involved in ventral spinal cord interneuron specification-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0060364-&&-frontal suture morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0043627-&&-response to estrogen-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0007411-&&-axon guidance-%%-GO:0001656-&&-metanephros development-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0042060-&&-wound healing-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0007442-&&-hindgut morphogenesis-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0048589-&&-developmental growth-%%-GO:0060840-&&-artery development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0021798-&&-forebrain dorsal/ventral pattern formation-%%-GO:0043586-&&-tongue development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0060367-&&-sagittal suture morphogenesis-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021776-&&-smoothened signaling pathway involved in spinal cord motor neuron cell fate specification-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:0021861-&&-forebrain radial glial cell differentiation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0021631-&&-optic nerve morphogenesis-%%-GO:0060875-&&-lateral semicircular canal development-%%-GO:0022018-&&-lateral ganglionic eminence cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0060021-&&-palate development-%%-GO:0070242-&&-thymocyte apoptotic process-%%-GO:0016485-&&-protein processing-%%-GO:0060873-&&-anterior semicircular canal development-%%-GO:0060594-&&-mammary gland specification-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0021766-&&-hippocampus development-%%-GO:0046639-&&-negative regulation of alpha-beta T cell differentiation-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0061005-&&-cell differentiation involved in kidney development-%%-GO:0035108-&&-limb morphogenesis-%%-GO:0060831-&&-smoothened signaling pathway involved in dorsal/ventral neural tube patterning-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0060366-&&-lambdoid suture morphogenesis|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0097542-&&-ciliary tip-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005930-&&-axoneme-%%-GO:0005929-&&-cilium-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0097546-&&-ciliary base-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008013-&&-beta-catenin binding	G:9606:GLI3			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05217-&&-Basal cell carcinoma	GLI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLI3	0.37328707	0.15714286	21	4	FALSE	GLI3	GLI3	177.8571429	0	21	0	0.72018276	FALSE	0	GLI3	31820	0.08480509
793236	taxon:9606	2.86403025	4.36E-05	180480	1902	5-hydroxytryptamine receptor 2A	gene	biological_process-&-1&-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0030431-&&-sleep-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0008219-&&-cell death-%%-GO:0050795-&&-regulation of behavior-%%-GO:0050966-&&-detection of mechanical stimulus involved in sensory perception of pain-%%-GO:0010513-&&-positive regulation of phosphatidylinositol biosynthetic process-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0042493-&&-response to drug-%%-GO:0044380-&&-protein localization to cytoskeleton-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0014824-&&-artery smooth muscle contraction-%%-GO:0014832-&&-urinary bladder smooth muscle contraction-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007210-&&-serotonin receptor signaling pathway-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046883-&&-regulation of hormone secretion-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051967-&&-negative regulation of synaptic transmission, glutamatergic-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0014059-&&-regulation of dopamine secretion-%%-GO:0007208-&&-phospholipase C-activating serotonin receptor signaling pathway-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0007568-&&-aging-%%-GO:0007613-&&-memory|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0070852-&&-cell body fiber|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0004993-&&-G-protein coupled serotonin receptor activity-%%-GO:0071886-&&-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0030594-&&-neurotransmitter receptor activity-%%-GO:0051378-&&-serotonin binding-%%-GO:0008144-&&-drug binding-%%-GO:0032403-&&-protein complex binding	G:9606:HTR2A	HTR2A	TRUE	KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	HTR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTR2A	0.34915832	0.02857143	21	5	FALSE	HTR2A	HTR2A	67.52380952	0	21	0	0.68932829	FALSE	0	HTR2A	42490	0.06506548
787053	taxon:9606	2.7809989	1.64E-05	180162	1902	isocitrate dehydrogenase 3 (NAD(+)) gamma	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0006102-&&-isocitrate metabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004449-&&-isocitrate dehydrogenase (NAD+) activity-%%-GO:0005524-&&-ATP binding-%%-GO:0051287-&&-NAD binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:IDH3G			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways	IDH3G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDH3G	0.35958303	0.13157895	20	4	FALSE	IDH3G	IDH3G	125.3	0	20	0	0.70316685	FALSE	0	IDH3G	26620	0.0820118
787110	taxon:9606	2.87285332	2.26E-04	180041	1902	C-X-C motif chemokine ligand 8	gene	biological_process-&-1&-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0042119-&&-neutrophil activation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007165-&&-signal transduction-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0001525-&&-angiogenesis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0031623-&&-receptor internalization-%%-GO:0006935-&&-chemotaxis-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0006955-&&-immune response-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0045091-&&-regulation of single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:2000535-&&-regulation of entry of bacterium into host cell-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030155-&&-regulation of cell adhesion|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005153-&&-interleukin-8 receptor binding-%%-GO:0008009-&&-chemokine activity	G:9606:CXCL8	CXCL8	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa05131-&&-Shigellosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05219-&&-Bladder cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	CXCL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL8	0.34808599	0.08496732	20	4	FALSE	CXCL8	CXCL8	60.5	0	19	0	0.68785778	FALSE	1	CXCL8	246126	0.06377731
787371	taxon:9606	2.69371357	1.12E-05	163157	1902	decapping mRNA 1B	gene	biological_process-&-1&-GO:0031087-&&-deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0000290-&&-deadenylation-dependent decapping of nuclear-transcribed mRNA-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008047-&&-enzyme activator activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0030234-&&-enzyme regulator activity	G:9606:DCP1B			KEGG-&-1&-hsa03018-&&-RNA degradation	DCP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCP1B	0.37123472	0.21578947	20	4	FALSE	DCP1B	DCP1B	148.15	0	20	0	0.71771441	FALSE	0	DCP1B	20572	0.07260912
787405	taxon:9606	2.59098787	3.22E-05	179481	1902	neural cell adhesion molecule 1	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0007155-&&-cell adhesion-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031225-&&-anchored component of membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:NCAM1			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05020-&&-Prion diseases	NCAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAM1	0.38595318	0.09803922	20	4	FALSE	NCAM1	NCAM1	222.9444444	0	19	0	0.73483536	FALSE	1	NCAM1	47838	0.08483655
787434	taxon:9606	2.58547345	1.81E-05	179440	1902	galectin 7	gene		G:9606:LGALS7				LGALS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS7	0.38677636	0.26797386	20	4	FALSE	LGALS7	LGALS7	307.2222222	0	19	0	0.73575442	FALSE	1	LGALS7	34274	0.11324077
787498	taxon:9606	3.06507011	5.24E-05	179336	1902	matrix metallopeptidase 1	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0016032-&&-viral process-%%-GO:0006508-&&-proteolysis-%%-GO:0032461-&&-positive regulation of protein oligomerization|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:MMP1	MMP1	TRUE	KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	MMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP1	0.32625681	0.03921569	20	5	FALSE	MMP1	MMP1	25	0	19	0	0.65582165	FALSE	1	MMP1	44466	0.06885759
787611	taxon:9606	2.69339846	1.46E-05	179107	1902	nuclear factor related to kappaB binding protein	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006954-&&-inflammatory response-%%-GO:0006310-&&-DNA recombination-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031011-&&-Ino80 complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding	G:9606:NFRKB				NFRKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFRKB	0.37127815	0.2	20	4	FALSE	NFRKB	NFRKB	165.15	0	20	0	0.71776692	FALSE	0	NFRKB	22580	0.08105651
787654	taxon:9606	2.694974	1.28E-05	162620	1902	potassium channel tetramerization domain containing 13	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0043149-&&-stress fiber assembly-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006260-&&-DNA replication-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0017049-&&-GTP-Rho binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:KCTD13				KCTD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCTD13	0.37106109	0.09803922	20	4	FALSE	KCTD13	KCTD13	156.8888889	0	19	0	0.71750433	FALSE	1	KCTD13	20396	0.07773364
787745	taxon:9606	2.56341579	2.35E-05	178850	1902	RNA polymerase mitochondrial	gene	biological_process-&-1&-GO:0006390-&&-transcription from mitochondrial promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006391-&&-transcription initiation from mitochondrial promoter|cellular_component-&-1&-GO:0034245-&&-mitochondrial DNA-directed RNA polymerase complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity-%%-GO:0000997-&&-mitochondrial RNA polymerase core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:POLRMT				POLRMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLRMT	0.39010449	0.12631579	20	4	FALSE	POLRMT	POLRMT	279.6	0	20	0	0.7394307	FALSE	0	POLRMT	48772	0.09848431
787925	taxon:9606	2.75011817	2.36E-04	178591	1902	ornithine decarboxylase antizyme 1	gene	biological_process-&-1&-GO:0006595-&&-polyamine metabolic process-%%-GO:0006596-&&-polyamine biosynthetic process-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006810-&&-transport-%%-GO:1902268-&&-negative regulation of polyamine transmembrane transport-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008073-&&-ornithine decarboxylase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:OAZ1				OAZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OAZ1	0.36362074	0.03921569	20	4	FALSE	OAZ1	OAZ1	114.1666667	0	19	0	0.70831364	FALSE	1	OAZ1	242680	0.06694821
787927	taxon:9606	2.86970222	1.49E-04	178586	1902	ornithine decarboxylase 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0033387-&&-putrescine biosynthetic process from ornithine-%%-GO:0006595-&&-polyamine metabolic process-%%-GO:0009615-&&-response to virus-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0001822-&&-kidney development|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004586-&&-ornithine decarboxylase activity-%%-GO:0005515-&&-protein binding	G:9606:ODC1	ODC1	TRUE	KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa00480-&&-Glutathione metabolism-%%-hsa01100-&&-Metabolic pathways	ODC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ODC1	0.34846821	0.0130719	20	5	FALSE	ODC1	ODC1	73.38888889	0	19	0	0.68838296	FALSE	1	ODC1	172976	0.07176613
787959	taxon:9606	2.86009138	2.78E-05	178507	1902	paired box 2	gene	biological_process-&-1&-GO:0072221-&&-metanephric distal convoluted tubule development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0003406-&&-retinal pigment epithelium development-%%-GO:0001823-&&-mesonephros development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1900212-&&-negative regulation of mesenchymal cell apoptotic process involved in metanephros development-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0035566-&&-regulation of metanephros size-%%-GO:0090102-&&-cochlea development-%%-GO:0035799-&&-ureter maturation-%%-GO:0021554-&&-optic nerve development-%%-GO:0072307-&&-regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0007501-&&-mesodermal cell fate specification-%%-GO:0072305-&&-negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:1900215-&&-negative regulation of apoptotic process involved in metanephric collecting duct development-%%-GO:1900218-&&-negative regulation of apoptotic process involved in metanephric nephron tubule development-%%-GO:2000597-&&-positive regulation of optic nerve formation-%%-GO:0001843-&&-neural tube closure-%%-GO:0010001-&&-glial cell differentiation-%%-GO:0021631-&&-optic nerve morphogenesis-%%-GO:0061360-&&-optic chiasma development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0072289-&&-metanephric nephron tubule formation-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0072300-&&-positive regulation of metanephric glomerulus development-%%-GO:0003337-&&-mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0043010-&&-camera-type eye development-%%-GO:0021633-&&-optic nerve structural organization-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0072108-&&-positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0039003-&&-pronephric field specification-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0072207-&&-metanephric epithelium development-%%-GO:0072205-&&-metanephric collecting duct development-%%-GO:0021650-&&-vestibulocochlear nerve formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007568-&&-aging-%%-GO:0072075-&&-metanephric mesenchyme development-%%-GO:0045918-&&-negative regulation of cytolysis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0072162-&&-metanephric mesenchymal cell differentiation-%%-GO:0048793-&&-pronephros development-%%-GO:0072189-&&-ureter development-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:2000594-&&-positive regulation of metanephric DCT cell differentiation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0002072-&&-optic cup morphogenesis involved in camera-type eye development-%%-GO:0007409-&&-axonogenesis-%%-GO:0001709-&&-cell fate determination-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0001655-&&-urogenital system development-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0072179-&&-nephric duct formation-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0007601-&&-visual perception|cellular_component-&-1&-GO:0034451-&&-centriolar satellite-%%-GO:0005730-&&-nucleolus-%%-GO:0005764-&&-lysosome-%%-GO:0005634-&&-nucleus-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding	G:9606:PAX2				PAX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAX2	0.34963918	0.02631579	20	5	FALSE	PAX2	PAX2	78.55	0	20	0	0.68998477	FALSE	0	PAX2	27520	0.07028004
787993	taxon:9606	2.97778478	5.75E-05	178442	1902	platelet derived growth factor subunit B	gene	biological_process-&-1&-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0060326-&&-cell chemotaxis-%%-GO:1900127-&&-positive regulation of hyaluronan biosynthetic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070528-&&-protein kinase C signaling-%%-GO:0035655-&&-interleukin-18-mediated signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:1905064-&&-negative regulation of vascular smooth muscle cell differentiation-%%-GO:0009611-&&-response to wounding-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0007507-&&-heart development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0010512-&&-negative regulation of phosphatidylinositol biosynthetic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0035793-&&-positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0072255-&&-metanephric glomerular mesangial cell development-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0003104-&&-positive regulation of glomerular filtration-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030097-&&-hemopoiesis-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:2000591-&&-positive regulation of metanephric mesenchymal cell migration-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0038001-&&-paracrine signaling-%%-GO:0072126-&&-positive regulation of glomerular mesangial cell proliferation-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:1905176-&&-positive regulation of vascular smooth muscle cell dedifferentiation-%%-GO:0001892-&&-embryonic placenta development-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0071506-&&-cellular response to mycophenolic acid-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0009986-&&-cell surface-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016323-&&-basolateral plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0016176-&&-superoxide-generating NADPH oxidase activator activity-%%-GO:0005518-&&-collagen binding-%%-GO:0042056-&&-chemoattractant activity	G:9606:PDGFB			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	PDGFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFB	0.33582011	0.16993464	20	5	FALSE	PDGFB	PDGFB	41.16666667	0	19	0	0.6703692	FALSE	1	PDGFB	87088	0.07828766
787997	taxon:9606	2.63573342	2.88E-05	178432	1902	pyruvate dehydrogenase kinase 3	gene	biological_process-&-1&-GO:0071398-&&-cellular response to fatty acid-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0035357-&&-peroxisome proliferator activated receptor signaling pathway-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0097411-&&-hypoxia-inducible factor-1alpha signaling pathway-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0006006-&&-glucose metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004740-&&-pyruvate dehydrogenase (acetyl-transferring) kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PDK3				PDK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDK3	0.37940104	0.26315789	20	4	FALSE	PDK3	PDK3	200.35	0	20	0	0.72737776	FALSE	0	PDK3	35498	0.08479458
788356	taxon:9606	2.70190641	9.57E-05	177812	1902	syndecan 1	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0055002-&&-striated muscle cell development-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0051592-&&-response to calcium ion-%%-GO:0048627-&&-myoblast development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0009636-&&-response to toxic substance-%%-GO:0001657-&&-ureteric bud development-%%-GO:0042476-&&-odontogenesis-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006954-&&-inflammatory response-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0042060-&&-wound healing-%%-GO:0051591-&&-response to cAMP-%%-GO:0060009-&&-Sertoli cell development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0009986-&&-cell surface-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding	G:9606:SDC1			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05144-&&-Malaria	SDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDC1	0.37010904	0.04736842	20	4	FALSE	SDC1	SDC1	118.05	0	20	0	0.71634893	FALSE	0	SDC1	84588	0.06132568
788396	taxon:9606	2.88041594	4.48E-05	177740	1902	stromal interaction molecule 1	gene	biological_process-&-1&-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0002115-&&-store-operated calcium entry-%%-GO:2001256-&&-regulation of store-operated calcium entry-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0070166-&&-enamel mineralization-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0032237-&&-activation of store-operated calcium channel activity-%%-GO:0005513-&&-detection of calcium ion|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0032541-&&-cortical endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0051010-&&-microtubule plus-end binding-%%-GO:0042802-&&-identical protein binding	G:9606:STIM1			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04611-&&-Platelet activation	STIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STIM1	0.34717208	0.08496732	20	4	FALSE	STIM1	STIM1	82	0	19	0	0.68659734	FALSE	1	STIM1	42768	0.08077811
788439	taxon:9606	2.55412006	2.05E-05	177669	1902	Ski2 like RNA helicase	gene	biological_process-&-1&-GO:0070478-&&-nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0055087-&&-Ski complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:SKIV2L			KEGG-&-1&-hsa03018-&&-RNA degradation	SKIV2L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SKIV2L	0.39152427	0.17368421	20	4	FALSE	SKIV2L	SKIV2L	275.55	0	20	0	0.74097999	FALSE	0	SKIV2L	37138	0.09582463
788444	taxon:9606	2.72664251	2.77E-05	144898	1902	RNF103-CHMP3 readthrough	gene		G:9606:RNF103-CHMP3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	RNF103-CHMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF103-CHMP3	0.36675142	0.19607843	20	5	FALSE	RNF103-CHMP3	RNF103-CHMP3	125.5555556	0	19	0	0.71222625	FALSE	1	RNF103-CHMP3	35168	0.06894869
788986	taxon:9606	2.6218686	1.72E-05	176459	1902	nuclear receptor coactivator 4	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0044754-&&-autolysosome|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0050681-&&-androgen receptor binding	G:9606:NCOA4	NCOA4	TRUE	KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer-%%-hsa04216-&&-Ferroptosis	NCOA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA4	0.38140737	0.14736842	20	4	FALSE	NCOA4	NCOA4	206.4	0	20	0	0.72968857	FALSE	0	NCOA4	33554	0.08378708
788991	taxon:9606	2.75389948	2.93E-05	160052	1902	inhibitor of CDK, cyclin A1 interacting protein 1	gene	biological_process-&-1&-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004861-&&-cyclin-dependent protein serine/threonine kinase inhibitor activity-%%-GO:0030332-&&-cyclin binding-%%-GO:0005515-&&-protein binding	G:9606:INCA1				INCA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INCA1	0.36312146	0.03157895	20	5	FALSE	INCA1	INCA1	110.25	0	20	0	0.70768342	FALSE	0	INCA1	37182	0.06579736
789075	taxon:9606	2.84433591	1.16E-05	176240	1902	suppressor of cytokine signaling 2	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0060396-&&-growth hormone receptor signaling pathway-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0032355-&&-response to estradiol|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0008269-&&-JAK pathway signal transduction adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005131-&&-growth hormone receptor binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:SOCS2			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS2	0.35157592	0.21578947	20	5	FALSE	SOCS2	SOCS2	109.15	0	20	0	0.69261068	FALSE	0	SOCS2	21942	0.09565789
789088	taxon:9606	2.72616984	1.42E-05	176215	1902	period circadian clock 2	gene	biological_process-&-1&-GO:0019249-&&-lactate biosynthetic process-%%-GO:0097167-&&-circadian regulation of translation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0042754-&&-negative regulation of circadian rhythm-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0002931-&&-response to ischemia-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0070345-&&-negative regulation of fat cell proliferation-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0051946-&&-regulation of glutamate uptake involved in transmission of nerve impulse-%%-GO:0007623-&&-circadian rhythm-%%-GO:0031397-&&-negative regulation of protein ubiquitination-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0070932-&&-histone H3 deacetylation-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:PER2	PER2	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04710-&&-Circadian rhythm-%%-hsa04713-&&-Circadian entrainment	PER2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PER2	0.366815	0.41578947	20	4	FALSE	PER2	PER2	156	0	20	0	0.71230503	FALSE	0	PER2	23878	0.08601765
789109	taxon:9606	2.7148259	3.09E-05	176183	1902	adaptor related protein complex 1 sigma 2 subunit	gene	biological_process-&-1&-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030119-&&-AP-type membrane coat adaptor complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:AP1S2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1S2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1S2	0.36834775	0.24736842	20	4	FALSE	AP1S2	AP1S2	128.8	0	20	0	0.71419568	FALSE	0	AP1S2	27268	0.06787223
789222	taxon:9606	2.74870017	2.72E-05	175971	1902	delta 4-desaturase, sphingolipid 1	gene	biological_process-&-1&-GO:0046513-&&-ceramide biosynthetic process-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006636-&&-unsaturated fatty acid biosynthetic process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0042284-&&-sphingolipid delta-4 desaturase activity-%%-GO:0009055-&&-electron carrier activity	G:9606:DEGS1			KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	DEGS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEGS1	0.36380832	0.02105263	20	4	FALSE	DEGS1	DEGS1	107.45	0	20	0	0.70854997	FALSE	0	DEGS1	31746	0.06327014
789223	taxon:9606	2.66834725	2.10E-05	175970	1902	density regulated re-initiation and release factor	gene	biological_process-&-1&-GO:0002188-&&-translation reinitiation-%%-GO:0032790-&&-ribosome disassembly-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0002192-&&-IRES-dependent translational initiation|cellular_component-&-1&-GO:0070992-&&-translation initiation complex-%%-GO:0005575-&&-cellular_component-%%-GO:0005840-&&-ribosome|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0003674-&&-molecular_function-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043022-&&-ribosome binding	G:9606:DENR				DENR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DENR	0.37476382	0.07894737	20	4	FALSE	DENR	DENR	167.8	0	20	0	0.72194212	FALSE	0	DENR	29768	0.07691778
789275	taxon:9606	2.75027572	1.57E-05	175841	1902	sorting nexin 4	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:1903595-&&-positive regulation of histamine secretion by mast cell-%%-GO:0016050-&&-vesicle organization-%%-GO:0006897-&&-endocytosis-%%-GO:0032456-&&-endocytic recycling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0031901-&&-early endosome membrane-%%-GO:0043234-&&-protein complex-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005158-&&-insulin receptor binding-%%-GO:1990459-&&-transferrin receptor binding-%%-GO:1990460-&&-leptin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:SNX4			KEGG-&-1&-hsa04144-&&-Endocytosis	SNX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX4	0.36359991	0.10457516	20	4	FALSE	SNX4	SNX4	124.4444444	0	19	0	0.70828738	FALSE	1	SNX4	22426	0.0742515
789392	taxon:9606	2.65983929	2.89E-05	175588	1902	cytohesin 2	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006897-&&-endocytosis-%%-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030426-&&-growth cone-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0070679-&&-inositol 1,4,5 trisphosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:CYTH2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04072-&&-Phospholipase D signaling pathway	CYTH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYTH2	0.37596256	0.16315789	20	4	FALSE	CYTH2	CYTH2	175.65	0	20	0	0.72336012	FALSE	0	CYTH2	36342	0.07957842
789449	taxon:9606	2.74318576	2.26E-05	175441	1902	golgi SNAP receptor complex member 1	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0048209-&&-regulation of vesicle targeting, to, from or within Golgi-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0006906-&&-vesicle fusion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005797-&&-Golgi medial cisterna-%%-GO:0031201-&&-SNARE complex-%%-GO:0005801-&&-cis-Golgi network-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0000149-&&-SNARE binding-%%-GO:0005484-&&-SNAP receptor activity	G:9606:GOSR1			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport	GOSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOSR1	0.36453966	0.25263158	20	4	FALSE	GOSR1	GOSR1	119.6	0	20	0	0.70946904	FALSE	0	GOSR1	27044	0.06863871
789472	taxon:9606	2.75295415	1.46E-05	175391	1902	MAD2L1 binding protein	gene	biological_process-&-1&-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0007096-&&-regulation of exit from mitosis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAD2L1BP				MAD2L1BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAD2L1BP	0.36324615	0.12418301	20	4	FALSE	MAD2L1BP	MAD2L1BP	143.7777778	0	19	0	0.70784097	FALSE	1	MAD2L1BP	24002	0.08647925
789483	taxon:9606	2.74176776	2.90E-05	175366	1902	T-cell leukemia/lymphoma 1B	gene		G:9606:TCL1B			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	TCL1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCL1B	0.36472819	0.31052632	20	5	FALSE	TCL1B	TCL1B	123.5	0	20	0	0.70970537	FALSE	0	TCL1B	31382	0.07186589
789637	taxon:9606	2.85631007	8.46E-06	158627	1902	ankyrin repeat and SOCS box containing 18	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:ASB18				ASB18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB18	0.35010205	0.05263158	20	5	FALSE	ASB18	ASB18	97.4	0	20	0	0.69061499	FALSE	0	ASB18	13516	0.08714029
789642	taxon:9606	2.71734678	4.55E-05	174990	1902	calcium voltage-gated channel auxiliary subunit gamma 2	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0098943-&&-neurotransmitter receptor transport, postsynaptic endosome to lysosome-%%-GO:0098970-&&-postsynaptic neurotransmitter receptor diffusion trapping-%%-GO:0006810-&&-transport-%%-GO:0061337-&&-cardiac conduction-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0099590-&&-neurotransmitter receptor internalization-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0051899-&&-membrane depolarization-%%-GO:0070588-&&-calcium ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0099634-&&-postsynaptic specialization membrane-%%-GO:0005891-&&-voltage-gated calcium channel complex|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0016247-&&-channel regulator activity-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005245-&&-voltage-gated calcium channel activity	G:9606:CACNG2			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	CACNG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACNG2	0.36800603	0.11578947	20	5	FALSE	CACNG2	CACNG2	127.6	0	20	0	0.71377554	FALSE	0	CACNG2	47388	0.06752386
789709	taxon:9606	2.70363951	2.04E-05	174850	1902	ubiquitin D	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0070842-&&-aggresome assembly-%%-GO:0032446-&&-protein modification by small protein conjugation-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center-%%-GO:0016235-&&-aggresome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0070628-&&-proteasome binding	G:9606:UBD				UBD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBD	0.36987179	0.1	20	4	FALSE	UBD	UBD	150.65	0	20	0	0.71606008	FALSE	0	UBD	27006	0.07717001
789799	taxon:9606	2.65337955	1.46E-05	174636	1902	POP7 homolog, ribonuclease P/MRP subunit	gene	biological_process-&-1&-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0001682-&&-tRNA 5'-leader removal-%%-GO:0008033-&&-tRNA processing|cellular_component-&-1&-GO:0005655-&&-nucleolar ribonuclease P complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004526-&&-ribonuclease P activity-%%-GO:0005515-&&-protein binding	G:9606:POP7			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03013-&&-RNA transport	POP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POP7	0.37687786	0.18300654	20	4	FALSE	POP7	POP7	204.4444444	0	19	0	0.72443674	FALSE	1	POP7	28066	0.09011856
789840	taxon:9606	2.67717032	3.55E-06	174538	1902	DBF4 zinc finger	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0006260-&&-DNA replication-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005515-&&-protein binding	G:9606:DBF4			KEGG-&-1&-hsa04110-&&-Cell cycle	DBF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBF4	0.37352872	0.40522876	20	4	FALSE	DBF4	DBF4	209.5555556	0	19	0	0.72047161	FALSE	1	DBF4	11460	0.09753259
789853	taxon:9606	2.80935875	2.36E-05	174510	1902	proline rich nuclear receptor coactivator 1	gene	biological_process-&-1&-GO:0031087-&&-deadenylation-independent decapping of nuclear-transcribed mRNA-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PNRC1				PNRC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNRC1	0.35595312	0.08496732	20	5	FALSE	PNRC1	PNRC1	106.9444444	0	19	0	0.69844021	FALSE	1	PNRC1	25664	0.07937692
789929	taxon:9606	2.61903261	1.59E-05	174332	1902	DNA polymerase delta 3, accessory subunit	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006261-&&-DNA-dependent DNA replication-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0006298-&&-mismatch repair-%%-GO:0000723-&&-telomere maintenance-%%-GO:0000731-&&-DNA synthesis involved in DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0019985-&&-translesion synthesis|cellular_component-&-1&-GO:0043625-&&-delta DNA polymerase complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003887-&&-DNA-directed DNA polymerase activity-%%-GO:0005515-&&-protein binding	G:9606:POLD3			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03410-&&-Base excision repair-%%-hsa03440-&&-Homologous recombination-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	POLD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLD3	0.38182037	0.18421053	20	4	FALSE	POLD3	POLD3	193.3	0	20	0	0.73016123	FALSE	0	POLD3	29558	0.07821862
789933	taxon:9606	2.71545612	1.76E-05	174320	1902	YME1 like 1 ATPase	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0035694-&&-mitochondrial protein catabolic process-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016604-&&-nuclear body-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008237-&&-metallopeptidase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004176-&&-ATP-dependent peptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:YME1L1				YME1L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YME1L1	0.36826226	0.08947368	20	4	FALSE	YME1L1	YME1L1	131.55	0	20	0	0.71409065	FALSE	0	YME1L1	29976	0.06860283
789960	taxon:9606	2.674807	4.18E-05	174237	1902	vacuolar protein sorting 45 homolog	gene	biological_process-&-1&-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0010008-&&-endosome membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:VPS45			KEGG-&-1&-hsa04144-&&-Endocytosis	VPS45	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS45	0.37385875	0.06842105	20	4	FALSE	VPS45	VPS45	142.65	0	20	0	0.7208655	FALSE	0	VPS45	47374	0.06618605
789993	taxon:9606	2.61509375	2.97E-05	174172	1902	Rho related BTB domain containing 3	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0042147-&&-retrograde transport, endosome to Golgi|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0005515-&&-protein binding	G:9606:RHOBTB3				RHOBTB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOBTB3	0.38239547	0.07843137	20	4	FALSE	RHOBTB3	RHOBTB3	214.4444444	0	19	0	0.73081771	FALSE	1	RHOBTB3	46662	0.08531509
789996	taxon:9606	2.76587364	2.41E-05	174153	1902	NLR family pyrin domain containing 1	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0032495-&&-response to muramyl dipeptide-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005634-&&-nucleus-%%-GO:0072558-&&-NLRP1 inflammasome complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0097110-&&-scaffold protein binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005524-&&-ATP binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:NLRP1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	NLRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP1	0.36154942	0.1372549	20	4	FALSE	NLRP1	NLRP1	125.6666667	0	19	0	0.70568773	FALSE	1	NLRP1	30944	0.07770898
790151	taxon:9606	2.70489995	3.73E-05	173756	1902	transcription factor 25	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007507-&&-heart development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TCF25				TCF25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCF25	0.36969944	0.09473684	20	4	FALSE	TCF25	TCF25	137.6	0	20	0	0.71585001	FALSE	0	TCF25	42524	0.06965465
790178	taxon:9606	2.58610367	3.93E-05	173705	1902	pyridoxal dependent decarboxylase domain containing 1	gene	biological_process-&-1&-GO:0019752-&&-carboxylic acid metabolic process|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0045296-&&-cadherin binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0016831-&&-carboxy-lyase activity	G:9606:PDXDC1				PDXDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDXDC1	0.3866821	0.08947368	20	4	FALSE	PDXDC1	PDXDC1	228.05	0	20	0	0.73564939	FALSE	0	PDXDC1	64546	0.08517757
790308	taxon:9606	2.63273988	3.41E-05	173360	1902	armadillo repeat containing 8	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0035580-&&-specific granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ARMC8				ARMC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARMC8	0.37983244	0.15263158	20	4	FALSE	ARMC8	ARMC8	176.35	0	20	0	0.72787669	FALSE	0	ARMC8	43524	0.07407563
790310	taxon:9606	2.70033086	4.57E-05	156974	1902	CDGSH iron sulfur domain 2	gene	biological_process-&-1&-GO:0000422-&&-mitophagy-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0010259-&&-multicellular organism aging|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:CISD2				CISD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CISD2	0.37032499	0.07368421	20	4	FALSE	CISD2	CISD2	145.1	0	20	0	0.71661152	FALSE	0	CISD2	63074	0.0731547
790330	taxon:9606	2.83708839	8.59E-06	173303	1902	NSL1, MIS12 kinetochore complex component	gene	biological_process-&-1&-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0051301-&&-cell division-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000444-&&-MIS12/MIND type complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NSL1				NSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSL1	0.35247404	0.30718954	20	5	FALSE	NSL1	NSL1	102.8333333	0	19	0	0.6938186	FALSE	1	NSL1	13718	0.08340092
790384	taxon:9606	2.69008981	1.26E-05	173159	1902	POZ/BTB and AT hook containing zinc finger 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030217-&&-T cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008584-&&-male gonad development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:PATZ1				PATZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PATZ1	0.3717348	0.14379085	20	4	FALSE	PATZ1	PATZ1	199.3333333	0	19	0	0.71831837	FALSE	1	PATZ1	26164	0.0953788
790397	taxon:9606	2.55994958	3.31E-05	173120	1902	phospholipase D family member 3	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0070290-&&-N-acylphosphatidylethanolamine-specific phospholipase D activity-%%-GO:0005515-&&-protein binding-%%-GO:0004630-&&-phospholipase D activity	G:9606:PLD3			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00565-&&-Ether lipid metabolism	PLD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLD3	0.39063269	0.07894737	20	4	FALSE	PLD3	PLD3	253.75	0	20	0	0.7400084	FALSE	0	PLD3	74550	0.08988644
790483	taxon:9606	2.68882937	2.82E-05	172731	1902	transient receptor potential cation channel subfamily C member 4 associated protein	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0048820-&&-hair follicle maturation|cellular_component-&-1&-GO:0031464-&&-Cul4A-RING E3 ubiquitin ligase complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:TRPC4AP				TRPC4AP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPC4AP	0.37190906	0.27368421	20	4	FALSE	TRPC4AP	TRPC4AP	180.65	0	20	0	0.71852844	FALSE	0	TRPC4AP	33428	0.08843704
790597	taxon:9606	2.91318733	6.36E-06	172010	1902	serine/threonine kinase 36	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0003351-&&-epithelial cilium movement-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0007420-&&-brain development-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007228-&&-positive regulation of hh target transcription factor activity-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:STK36				STK36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK36	0.34326663	0.30065359	20	5	FALSE	STK36	STK36	243.7777778	0	19	0	0.68113544	FALSE	1	STK36	21268	0.27822222
790650	taxon:9606	2.58610367	3.93E-05	138889	1902	pyridoxal-dependent decarboxylase domain-containing protein 1	gene		G:9606:LOC102724985				LOC102724985	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC102724985	0.3866821	0.08947368	20	4	FALSE	LOC102724985	LOC102724985	228.05	0	20	0	0.73564939	FALSE	0	LOC102724985	64546	0.08517757
790712	taxon:9606	2.49015283	3.09E-05	171404	1902	pyrroline-5-carboxylate reductase family member 2	gene	biological_process-&-1&-GO:0055129-&&-L-proline biosynthetic process-%%-GO:0006561-&&-proline biosynthetic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004735-&&-pyrroline-5-carboxylate reductase activity	G:9606:PYCR2			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	PYCR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYCR2	0.40158178	0.08947368	20	4	FALSE	PYCR2	PYCR2	305.5	0	20	0	0.7516412	FALSE	0	PYCR2	61744	0.09357756
790732	taxon:9606	2.8192847	3.90E-07	171362	1902	lysine methyltransferase 5B	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034773-&&-histone H4-K20 trimethylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042799-&&-histone methyltransferase activity (H4-K20 specific)-%%-GO:0018024-&&-histone-lysine N-methyltransferase activity	G:9606:KMT5B			KEGG-&-1&-hsa00310-&&-Lysine degradation	KMT5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KMT5B	0.3546999	0.11764706	20	4	FALSE	KMT5B	KMT5B	262.5555556	0	19	0	0.69678588	FALSE	1	KMT5B	2310	0.19755873
790743	taxon:9606	2.58547345	1.81E-05	154956	1902	galectin 7B	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding	G:9606:LGALS7B				LGALS7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGALS7B	0.38677636	0.26797386	20	4	FALSE	LGALS7B	LGALS7B	307.2222222	0	19	0	0.73575442	FALSE	1	LGALS7B	34274	0.11324077
790920	taxon:9606	2.67575232	1.06E-04	170696	1902	lipolysis stimulated lipoprotein receptor	gene	biological_process-&-1&-GO:1904274-&&-tricellular tight junction assembly-%%-GO:0019216-&&-regulation of lipid metabolic process-%%-GO:0061833-&&-protein localization to tricellular tight junction-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0001889-&&-liver development-%%-GO:0060856-&&-establishment of blood-brain barrier|cellular_component-&-1&-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0034362-&&-low-density lipoprotein particle-%%-GO:0042627-&&-chylomicron-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0061689-&&-tricellular tight junction	G:9606:LSR				LSR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSR	0.37372667	0.06842105	20	4	FALSE	LSR	LSR	170.85	0	20	0	0.72070795	FALSE	0	LSR	107424	0.07996246
790937	taxon:9606	2.72664251	2.77E-05	170665	1902	charged multivesicular body protein 3	gene	biological_process-&-1&-GO:1901673-&&-regulation of mitotic spindle assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0039702-&&-viral budding via host ESCRT complex-%%-GO:0097352-&&-autophagosome maturation-%%-GO:0016236-&&-macroautophagy-%%-GO:0015031-&&-protein transport-%%-GO:0050792-&&-regulation of viral process-%%-GO:0010824-&&-regulation of centrosome duplication-%%-GO:0019058-&&-viral life cycle-%%-GO:2000641-&&-regulation of early endosome to late endosome transport-%%-GO:0007080-&&-mitotic metaphase plate congression-%%-GO:1902188-&&-positive regulation of viral release from host cell-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006997-&&-nucleus organization-%%-GO:0071985-&&-multivesicular body sorting pathway-%%-GO:0061763-&&-multivesicular body-lysosome fusion-%%-GO:0016197-&&-endosomal transport-%%-GO:1903541-&&-regulation of exosomal secretion-%%-GO:0051258-&&-protein polymerization-%%-GO:0000920-&&-cell separation after cytokinesis-%%-GO:0036258-&&-multivesicular body assembly-%%-GO:1902187-&&-negative regulation of viral release from host cell|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005770-&&-late endosome-%%-GO:0000815-&&-ESCRT III complex-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031902-&&-late endosome membrane|molecular_function-&-1&-GO:0031210-&&-phosphatidylcholine binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:CHMP3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04217-&&-Necroptosis	CHMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHMP3	0.36675142	0.19607843	20	5	FALSE	CHMP3	CHMP3	125.5555556	0	19	0	0.71222625	FALSE	1	CHMP3	35168	0.06894869
790957	taxon:9606	2.81707893	2.42E-05	170606	1902	inositol polyphosphate-5-phosphatase K	gene	biological_process-&-1&-GO:0046855-&&-inositol phosphate dephosphorylation-%%-GO:2000466-&&-negative regulation of glycogen (starch) synthase activity-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0016311-&&-dephosphorylation-%%-GO:2001153-&&-positive regulation of renal water transport-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0035305-&&-negative regulation of dephosphorylation-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0005979-&&-regulation of glycogen biosynthetic process-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0097178-&&-ruffle assembly-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0090315-&&-negative regulation of protein targeting to membrane-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0045869-&&-negative regulation of single stranded viral RNA replication via double stranded DNA intermediate-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0010829-&&-negative regulation of glucose transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0001726-&&-ruffle-%%-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004445-&&-inositol-polyphosphate 5-phosphatase activity-%%-GO:0046030-&&-inositol trisphosphate phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042577-&&-lipid phosphatase activity-%%-GO:0034595-&&-phosphatidylinositol phosphate 5-phosphatase activity-%%-GO:0052659-&&-inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity-%%-GO:0052658-&&-inositol-1,4,5-trisphosphate 5-phosphatase activity-%%-GO:0016312-&&-inositol bisphosphate phosphatase activity-%%-GO:0034594-&&-phosphatidylinositol trisphosphate phosphatase activity-%%-GO:0034485-&&-phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity-%%-GO:0004439-&&-phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity-%%-GO:0005000-&&-vasopressin receptor activity	G:9606:INPP5K			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	INPP5K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INPP5K	0.35497763	0.03684211	20	5	FALSE	INPP5K	INPP5K	103.75	0	20	0	0.69715351	FALSE	0	INPP5K	27980	0.07904215
791005	taxon:9606	2.48904994	2.24E-05	170439	1902	SHC adaptor protein 3	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0007611-&&-learning or memory-%%-GO:0035249-&&-synaptic transmission, glutamatergic-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:SHC3			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SHC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHC3	0.40175972	0.18421053	20	4	FALSE	SHC3	SHC3	281.35	0	20	0	0.75182501	FALSE	0	SHC3	53476	0.08608815
791021	taxon:9606	2.73010871	1.95E-05	170349	1902	aprataxin	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0000012-&&-single strand break repair-%%-GO:0016311-&&-dephosphorylation-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0031647-&&-regulation of protein stability|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0051219-&&-phosphoprotein binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0008967-&&-phosphoglycolate phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0033699-&&-DNA 5'-adenosine monophosphate hydrolase activity	G:9606:APTX				APTX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APTX	0.36628578	0.07368421	20	4	FALSE	APTX	APTX	136.95	0	20	0	0.71164855	FALSE	0	APTX	29248	0.07524807
791037	taxon:9606	2.84543879	6.08E-05	170287	1902	semaphorin 4C	gene	biological_process-&-1&-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0021549-&&-cerebellum development-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0021535-&&-cell migration in hindbrain-%%-GO:0001843-&&-neural tube closure-%%-GO:0042692-&&-muscle cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SEMA4C			KEGG-&-1&-hsa04360-&&-Axon guidance	SEMA4C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEMA4C	0.35143965	0.05789474	20	4	FALSE	SEMA4C	SEMA4C	86.45	0	20	0	0.69242687	FALSE	0	SEMA4C	61830	0.07237174
791063	taxon:9606	2.59744761	3.82E-05	170187	1902	transmembrane protein 132A	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TMEM132A				TMEM132A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM132A	0.38499333	0.07894737	20	4	FALSE	TMEM132A	TMEM132A	182.45	0	20	0	0.73375873	FALSE	0	TMEM132A	47972	0.06997695
791104	taxon:9606	2.60768867	2.13E-05	170032	1902	ATP binding cassette subfamily F member 3	gene	biological_process-&-1&-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0016887-&&-ATPase activity	G:9606:ABCF3				ABCF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCF3	0.38348136	0.16315789	20	4	FALSE	ABCF3	ABCF3	242.3	0	20	0	0.73205189	FALSE	0	ABCF3	47550	0.09484718
791169	taxon:9606	2.68142429	1.92E-05	169833	1902	Rap associating with DIL domain	gene	biological_process-&-1&-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0007165-&&-signal transduction-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RADIL				RADIL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RADIL	0.37293613	0.04736842	20	5	FALSE	RADIL	RADIL	145.9	0	20	0	0.71976262	FALSE	0	RADIL	31796	0.06977469
791207	taxon:9606	2.80116591	1.39E-05	169730	1902	lysine demethylase 3A	gene	biological_process-&-1&-GO:0046293-&&-formaldehyde biosynthetic process-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0036123-&&-histone H3-K9 dimethylation-%%-GO:2000036-&&-regulation of stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:2000736-&&-regulation of stem cell differentiation-%%-GO:0007290-&&-spermatid nucleus elongation-%%-GO:0009755-&&-hormone-mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0051213-&&-dioxygenase activity	G:9606:KDM3A			KEGG-&-1&-hsa04714-&&-Thermogenesis	KDM3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM3A	0.35699421	0.1	20	4	FALSE	KDM3A	KDM3A	103.5	0	20	0	0.69980568	FALSE	0	KDM3A	19414	0.07514556
791282	taxon:9606	2.76870963	2.42E-05	169371	1902	arrestin domain containing 3	gene	biological_process-&-1&-GO:0031651-&&-negative regulation of heat generation-%%-GO:0060613-&&-fat pad development-%%-GO:0090327-&&-negative regulation of locomotion involved in locomotory behavior-%%-GO:0043588-&&-skin development-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0044252-&&-negative regulation of multicellular organismal metabolic process-%%-GO:0071879-&&-positive regulation of adrenergic receptor signaling pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0031699-&&-beta-3 adrenergic receptor binding-%%-GO:0005515-&&-protein binding	G:9606:ARRDC3				ARRDC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRDC3	0.36117908	0.13684211	20	4	FALSE	ARRDC3	ARRDC3	122.7	0	20	0	0.70521506	FALSE	0	ARRDC3	27988	0.07847534
791285	taxon:9606	2.67449189	1.43E-05	169345	1902	megakaryoblastic leukemia (translocation) 1	gene	biological_process-&-1&-GO:0010735-&&-positive regulation of transcription via serum response element binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0043522-&&-leucine zipper domain binding-%%-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003785-&&-actin monomer binding	G:9606:MKL1				MKL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKL1	0.3739028	0.18300654	20	4	FALSE	MKL1	MKL1	201	0	19	0	0.72091802	FALSE	1	MKL1	24074	0.09406714
791311	taxon:9606	2.56703955	2.28E-05	169242	1902	OTU deubiquitinase 7B	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0002385-&&-mucosal immune response-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0002250-&&-adaptive immune response-%%-GO:0071947-&&-protein deubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035871-&&-protein K11-linked deubiquitination-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0032717-&&-negative regulation of interleukin-8 production-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0003677-&&-DNA binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:OTUD7B				OTUD7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUD7B	0.3895538	0.12631579	20	4	FALSE	OTUD7B	OTUD7B	223.35	0	20	0	0.73882674	FALSE	0	OTUD7B	36836	0.08014363
791354	taxon:9606	2.81613361	5.72E-06	169040	1902	mitochondrial ribosomal protein L17	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination-%%-GO:0000002-&&-mitochondrial genome maintenance|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPL17			KEGG-&-1&-hsa03010-&&-Ribosome	MRPL17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL17	0.35509679	0.25263158	20	5	FALSE	MRPL17	MRPL17	139.35	0	20	0	0.69731107	FALSE	0	MRPL17	11302	0.10617849
791456	taxon:9606	2.82968331	2.03E-05	168569	1902	zinc finger FYVE-type containing 21	gene	biological_process-&-1&-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0000285-&&-1-phosphatidylinositol-3-phosphate 5-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZFYVE21				ZFYVE21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFYVE21	0.35339644	0.09473684	20	4	FALSE	ZFYVE21	ZFYVE21	107.9	0	20	0	0.69505278	FALSE	0	ZFYVE21	38260	0.08305019
791538	taxon:9606	2.69844021	1.53E-05	168188	1902	F-box and leucine rich repeat protein 15	gene	biological_process-&-1&-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0030282-&&-bone mineralization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXL15				FBXL15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL15	0.37058446	0.13157895	20	4	FALSE	FBXL15	FBXL15	175.75	0	20	0	0.71692663	FALSE	0	FBXL15	27696	0.08763092
791620	taxon:9606	2.74224043	1.40E-05	167783	1902	gem nuclear organelle associated protein 6	gene	biological_process-&-1&-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0000387-&&-spliceosomal snRNP assembly-%%-GO:0051170-&&-nuclear import-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0034719-&&-SMN-Sm protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0032797-&&-SMN complex-%%-GO:0097504-&&-Gemini of coiled bodies|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GEMIN6			KEGG-&-1&-hsa03013-&&-RNA transport	GEMIN6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GEMIN6	0.36466533	0.45263158	20	5	FALSE	GEMIN6	GEMIN6	144.95	0	20	0	0.7096266	FALSE	0	GEMIN6	22718	0.0830086
791647	taxon:9606	2.82716244	9.15E-06	167589	1902	p53 and DNA damage regulated 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0016272-&&-prefoldin complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding	G:9606:PDRG1				PDRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDRG1	0.35371155	0.24736842	20	4	FALSE	PDRG1	PDRG1	105.2	0	20	0	0.69547293	FALSE	0	PDRG1	13776	0.0832276
791721	taxon:9606	2.91145423	1.36E-05	167201	1902	fumarylacetoacetate hydrolase domain containing 1	gene	biological_process-&-1&-GO:0008152-&&-metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0018773-&&-acetylpyruvate hydrolase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0034545-&&-fumarylpyruvate hydrolase activity-%%-GO:0008948-&&-oxaloacetate decarboxylase activity-%%-GO:0047621-&&-acylpyruvate hydrolase activity	G:9606:FAHD1			KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa01100-&&-Metabolic pathways	FAHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAHD1	0.34347097	0.16339869	20	4	FALSE	FAHD1	FAHD1	72.61111111	0	19	0	0.68142429	FALSE	1	FAHD1	13698	0.0873591
791790	taxon:9606	2.58641878	1.48E-05	166858	1902	nucleoside-triphosphatase, cancer-related	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0098519-&&-nucleotide phosphatase activity, acting on free nucleotides-%%-GO:0003723-&&-RNA binding-%%-GO:0017111-&&-nucleoside-triphosphatase activity-%%-GO:0005524-&&-ATP binding	G:9606:NTPCR			KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	NTPCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTPCR	0.38663499	0.15789474	20	4	FALSE	NTPCR	NTPCR	297.7	0	20	0	0.73559687	FALSE	0	NTPCR	33754	0.11126076
791873	taxon:9606	2.60926422	2.76E-05	182951	1902	adducin 3	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005903-&&-brush border-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005516-&&-calmodulin binding	G:9606:ADD3				ADD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADD3	0.3832498	0.08421053	20	4	FALSE	ADD3	ADD3	193.55	0	20	0	0.7317893	FALSE	0	ADD3	49074	0.07581404
791889	taxon:9606	2.84654167	3.26E-05	182923	1902	adrenoceptor beta 1	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0001997-&&-positive regulation of the force of heart contraction by epinephrine-norepinephrine-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0001996-&&-positive regulation of heart rate by epinephrine-norepinephrine-%%-GO:0031649-&&-heat generation-%%-GO:0040015-&&-negative regulation of multicellular organism growth-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:0042596-&&-fear response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0002025-&&-vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0001659-&&-temperature homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005769-&&-early endosome|molecular_function-&-1&-GO:0004939-&&-beta-adrenergic receptor activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0051379-&&-epinephrine binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0051380-&&-norepinephrine binding-%%-GO:0031694-&&-alpha-2A adrenergic receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004940-&&-beta1-adrenergic receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:ADRB1	ADRB1	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04540-&&-Gap junction-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRB1	0.35130348	0.08947368	20	4	FALSE	ADRB1	ADRB1	83.55	0	20	0	0.69224305	FALSE	0	ADRB1	30786	0.07182916
791932	taxon:9606	2.67590988	5.06E-05	182852	1902	arachidonate 5-lipoxygenase	gene	biological_process-&-1&-GO:0019370-&&-leukotriene biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:2001300-&&-lipoxin metabolic process-%%-GO:0002540-&&-leukotriene production involved in inflammatory response-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005641-&&-nuclear envelope lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004051-&&-arachidonate 5-lipoxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005506-&&-iron ion binding	G:9606:ALOX5	ALOX5	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa05145-&&-Toxoplasmosis-%%-hsa00590-&&-Arachidonic acid metabolism	ALOX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALOX5	0.37370466	0.05263158	20	5	FALSE	ALOX5	ALOX5	147.4	0	20	0	0.72068169	FALSE	0	ALOX5	52638	0.07005246
791975	taxon:9606	2.57003309	3.21E-05	182783	1902	amyloid beta precursor protein binding family B member 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0001764-&&-neuron migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007411-&&-axon guidance-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0045202-&&-synapse-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0005515-&&-protein binding	G:9606:APBB2				APBB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBB2	0.38910005	0.13684211	20	4	FALSE	APBB2	APBB2	205.4	0	20	0	0.73832782	FALSE	0	APBB2	43950	0.07415974
791989	taxon:9606	2.62958878	5.94E-05	166380	1902	polyribonucleotide nucleotidyltransferase 1	gene	biological_process-&-1&-GO:0000964-&&-mitochondrial RNA 5'-end processing-%%-GO:0097421-&&-liver regeneration-%%-GO:0043631-&&-RNA polyadenylation-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0035928-&&-rRNA import into mitochondrion-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0000957-&&-mitochondrial RNA catabolic process-%%-GO:0006402-&&-mRNA catabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0060416-&&-response to growth hormone-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0070584-&&-mitochondrion morphogenesis-%%-GO:0097222-&&-mitochondrial mRNA polyadenylation-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0051591-&&-response to cAMP-%%-GO:2000627-&&-positive regulation of miRNA catabolic process-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0071042-&&-nuclear polyadenylation-dependent mRNA catabolic process-%%-GO:0000962-&&-positive regulation of mitochondrial RNA catabolic process-%%-GO:0000965-&&-mitochondrial RNA 3'-end processing-%%-GO:2000772-&&-regulation of cellular senescence-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0000958-&&-mitochondrial mRNA catabolic process-%%-GO:0043457-&&-regulation of cellular respiration-%%-GO:0035927-&&-RNA import into mitochondrion-%%-GO:0006401-&&-RNA catabolic process|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0045025-&&-mitochondrial degradosome-%%-GO:0042788-&&-polysomal ribosome|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0004654-&&-polyribonucleotide nucleotidyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0008266-&&-poly(U) RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0034046-&&-poly(G) binding	G:9606:PNPT1			KEGG-&-1&-hsa03018-&&-RNA degradation	PNPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNPT1	0.3802876	0.13684211	20	4	FALSE	PNPT1	PNPT1	206.05	0	20	0	0.72840187	FALSE	0	PNPT1	71750	0.08467709
792096	taxon:9606	2.52166378	1.90E-05	182615	1902	2',3'-cyclic nucleotide 3' phosphodiesterase	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0009214-&&-cyclic nucleotide catabolic process-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007409-&&-axonogenesis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0007568-&&-aging-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0016020-&&-membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0035748-&&-myelin sheath abaxonal region-%%-GO:0042470-&&-melanosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0035749-&&-myelin sheath adaxonal region-%%-GO:0031143-&&-pseudopodium|molecular_function-&-1&-GO:0004113-&&-2',3'-cyclic-nucleotide 3'-phosphodiesterase activity-%%-GO:0030551-&&-cyclic nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:CNP				CNP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNP	0.39656357	0.14736842	20	4	FALSE	CNP	CNP	290.75	0	20	0	0.74638937	FALSE	0	CNP	44960	0.09479608
792110	taxon:9606	2.6667717	5.99E-05	182598	1902	collagen type IV alpha 5 chain	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005605-&&-basal lamina-%%-GO:0005587-&&-collagen type IV trimer-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL4A5			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	COL4A5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A5	0.37498523	0.06315789	20	4	FALSE	COL4A5	COL4A5	169.65	0	20	0	0.72220472	FALSE	0	COL4A5	74942	0.07857474
792116	taxon:9606	2.66031196	5.60E-06	166195	1902	pleckstrin homology like domain family B member 2	gene	biological_process-&-1&-GO:0045184-&&-establishment of protein localization-%%-GO:1903690-&&-negative regulation of wound healing, spreading of epidermal cells-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:1904261-&&-positive regulation of basement membrane assembly involved in embryonic body morphogenesis-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0010470-&&-regulation of gastrulation|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0045180-&&-basal cortex-%%-GO:0005829-&&-cytosol-%%-GO:0031252-&&-cell leading edge-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PHLDB2				PHLDB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLDB2	0.37589577	0.16315789	20	4	FALSE	PHLDB2	PHLDB2	207.9	0	20	0	0.72328134	FALSE	0	PHLDB2	16814	0.0933513
792119	taxon:9606	2.6236017	2.19E-05	182572	1902	Kruppel like factor 6	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030183-&&-B cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:KLF6				KLF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF6	0.38115542	0.18421053	20	4	FALSE	KLF6	KLF6	195.2	0	20	0	0.72939972	FALSE	0	KLF6	32202	0.07978332
792185	taxon:9606	2.71120214	2.07E-05	182464	1902	ras homolog family member C	gene	biological_process-&-1&-GO:0000910-&&-cytokinesis-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0043297-&&-apical junction assembly-%%-GO:0060193-&&-positive regulation of lipase activity-%%-GO:1902766-&&-skeletal muscle satellite cell migration-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0032154-&&-cleavage furrow-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:RHOC				RHOC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOC	0.36884007	0.08947368	20	4	FALSE	RHOC	RHOC	161.55	0	20	0	0.71479964	FALSE	0	RHOC	30474	0.08531746
792280	taxon:9606	2.71514101	1.37E-05	182301	1902	cadherin 5	gene	biological_process-&-1&-GO:1903142-&&-positive regulation of establishment of endothelial barrier-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0034332-&&-adherens junction organization-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0016337-&&-single organismal cell-cell adhesion|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0030054-&&-cell junction-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0005102-&&-receptor binding-%%-GO:0044325-&&-ion channel binding	G:9606:CDH5	CDH5	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05418-&&-Fluid shear stress and atherosclerosis	CDH5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH5	0.368305	0.24736842	20	4	FALSE	CDH5	CDH5	150	0	20	0	0.71414316	FALSE	0	CDH5	19740	0.08017657
792300	taxon:9606	2.69733732	7.89E-06	182263	1902	caudal type homeobox 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0014807-&&-regulation of somitogenesis-%%-GO:0060575-&&-intestinal epithelial cell differentiation-%%-GO:0001568-&&-blood vessel development-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0030154-&&-cell differentiation-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0060711-&&-labyrinthine layer development|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:CDX2			KEGG-&-1&-hsa05226-&&-Gastric cancer	CDX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDX2	0.37073598	0.21568627	20	4	FALSE	CDX2	CDX2	204	0	19	0	0.71711045	FALSE	1	CDX2	17826	0.10196765
792306	taxon:9606	2.76272255	1.49E-05	182249	1902	centromere protein C	gene	biological_process-&-1&-GO:0051382-&&-kinetochore assembly-%%-GO:0051315-&&-attachment of mitotic spindle microtubules to kinetochore-%%-GO:0051455-&&-attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation-%%-GO:0051301-&&-cell division-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0007059-&&-chromosome segregation-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0000780-&&-condensed nuclear chromosome, centromeric region-%%-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0031618-&&-nuclear pericentric heterochromatin-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0000778-&&-condensed nuclear chromosome kinetochore|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0019237-&&-centromeric DNA binding	G:9606:CENPC				CENPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPC	0.36196179	0.07894737	20	5	FALSE	CENPC	CENPC	154.55	0	20	0	0.70621291	FALSE	0	CENPC	27186	0.09443425
792350	taxon:9606	2.81676383	1.80E-05	165795	1902	oligodendrocyte transcription factor 1	gene	biological_process-&-1&-GO:0048663-&&-neuron fate commitment-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:OLIG1				OLIG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OLIG1	0.35501734	0.08421053	20	4	FALSE	OLIG1	OLIG1	96.6	0	20	0	0.69720603	FALSE	0	OLIG1	22116	0.075078
792469	taxon:9606	2.77564204	3.99E-05	181969	1902	beta-2-microglobulin	gene	biological_process-&-1&-GO:0002480-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent-%%-GO:0001895-&&-retina homeostasis-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0071281-&&-cellular response to iron ion-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0045646-&&-regulation of erythrocyte differentiation-%%-GO:0002481-&&-antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent-%%-GO:0071283-&&-cellular response to iron(III) ion-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0042026-&&-protein refolding-%%-GO:0050776-&&-regulation of immune response-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:1900122-&&-positive regulation of receptor binding-%%-GO:0033216-&&-ferric iron import-%%-GO:1900121-&&-negative regulation of receptor binding-%%-GO:0045087-&&-innate immune response-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:1904437-&&-positive regulation of transferrin receptor binding-%%-GO:0019885-&&-antigen processing and presentation of endogenous peptide antigen via MHC class I-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:1903991-&&-positive regulation of ferrous iron import into cell-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1904434-&&-positive regulation of ferrous iron binding-%%-GO:0046686-&&-response to cadmium ion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:1990712-&&-HFE-transferrin receptor complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0031905-&&-early endosome lumen-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001948-&&-glycoprotein binding	G:9606:B2M			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05163-&&-Human cytomegalovirus infection	B2M	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B2M	0.36027701	0.06535948	20	4	FALSE	B2M	B2M	109.2222222	0	19	0	0.70405966	FALSE	1	B2M	39676	0.07293295
792588	taxon:9606	2.84118481	2.79E-05	181762	1902	CD9 molecule	gene	biological_process-&-1&-GO:0007342-&&-fusion of sperm to egg plasma membrane-%%-GO:0030913-&&-paranodal junction assembly-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0009414-&&-response to water deprivation-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0007420-&&-brain development-%%-GO:0002576-&&-platelet degranulation-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0007155-&&-cell adhesion-%%-GO:0030168-&&-platelet activation|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding	G:9606:CD9			KEGG-&-1&-hsa04640-&&-Hematopoietic cell lineage	CD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD9	0.35196584	0.12631579	20	5	FALSE	CD9	CD9	81.2	0	20	0	0.69313586	FALSE	0	CD9	26716	0.07187223
792637	taxon:9606	2.77012762	2.03E-05	181673	1902	CD19 molecule	gene	biological_process-&-1&-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006968-&&-cellular defense response-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0050853-&&-B cell receptor signaling pathway|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding	G:9606:CD19			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05340-&&-Primary immunodeficiency	CD19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD19	0.3609942	0.31578947	20	4	FALSE	CD19	CD19	146.5	0	20	0	0.70497873	FALSE	0	CD19	25366	0.09405909
792675	taxon:9606	2.66283283	8.93E-06	181579	1902	BMP/retinoic acid inducible neural specific 1	gene	biological_process-&-1&-GO:0071625-&&-vocalization behavior-%%-GO:0035640-&&-exploration behavior-%%-GO:0007614-&&-short-term memory-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0008219-&&-cell death-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0001662-&&-behavioral fear response-%%-GO:0042711-&&-maternal behavior-%%-GO:0035176-&&-social behavior-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0050768-&&-negative regulation of neurogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BRINP1				BRINP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRINP1	0.37553991	0.13157895	20	4	FALSE	BRINP1	BRINP1	196.25	0	20	0	0.72286119	FALSE	0	BRINP1	19958	0.08895191
792780	taxon:9606	2.57271152	2.72E-05	181380	1902	AT-rich interaction domain 3A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:ARID3A				ARID3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARID3A	0.38869496	0.10526316	20	4	FALSE	ARID3A	ARID3A	221.95	0	20	0	0.73788141	FALSE	0	ARID3A	63274	0.08094891
792830	taxon:9606	2.73562313	3.70E-05	181292	1902	EPH receptor A4	gene	biological_process-&-1&-GO:0048710-&&-regulation of astrocyte differentiation-%%-GO:0007628-&&-adult walking behavior-%%-GO:2001108-&&-positive regulation of Rho guanyl-nucleotide exchange factor activity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0021957-&&-corticospinal tract morphogenesis-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0072178-&&-nephric duct morphogenesis-%%-GO:0097156-&&-fasciculation of motor neuron axon-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007155-&&-cell adhesion-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0048681-&&-negative regulation of axon regeneration-%%-GO:0061001-&&-regulation of dendritic spine morphogenesis-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0097155-&&-fasciculation of sensory neuron axon-%%-GO:0008347-&&-glial cell migration|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0030175-&&-filopodium-%%-GO:0043197-&&-dendritic spine-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043204-&&-perikaryon-%%-GO:0009986-&&-cell surface-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0044295-&&-axonal growth cone-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0031901-&&-early endosome membrane-%%-GO:0043679-&&-axon terminus-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005005-&&-transmembrane-ephrin receptor activity-%%-GO:0042731-&&-PH domain binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0097161-&&-DH domain binding	G:9606:EPHA4			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA4	0.36554743	0.09803922	20	5	FALSE	EPHA4	EPHA4	140.2222222	0	19	0	0.71072948	FALSE	1	EPHA4	35552	0.07948232
792995	taxon:9606	2.8457539	2.58E-05	181024	1902	farnesyltransferase, CAAX box, alpha	gene	biological_process-&-1&-GO:0018343-&&-protein farnesylation-%%-GO:0018344-&&-protein geranylgeranylation-%%-GO:0045213-&&-neurotransmitter receptor metabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0099601-&&-regulation of neurotransmitter receptor activity-%%-GO:0090045-&&-positive regulation of deacetylase activity-%%-GO:0090044-&&-positive regulation of tubulin deacetylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005965-&&-protein farnesyltransferase complex-%%-GO:0005875-&&-microtubule associated complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005953-&&-CAAX-protein geranylgeranyltransferase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004661-&&-protein geranylgeranyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004662-&&-CAAX-protein geranylgeranyltransferase activity-%%-GO:0004663-&&-Rab geranylgeranyltransferase activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0030548-&&-acetylcholine receptor regulator activity-%%-GO:0004660-&&-protein farnesyltransferase activity-%%-GO:0043014-&&-alpha-tubulin binding	G:9606:FNTA			KEGG-&-1&-hsa00900-&&-Terpenoid backbone biosynthesis	FNTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FNTA	0.35140073	0.01052632	20	4	FALSE	FNTA	FNTA	71.2	0	20	0	0.69237435	FALSE	0	FNTA	22988	0.06605634
793054	taxon:9606	2.80762565	8.64E-06	164437	1902	ankyrin repeat and SOCS box containing 5	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005622-&&-intracellular	G:9606:ASB5				ASB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB5	0.35617284	0.07894737	20	4	FALSE	ASB5	ASB5	106.45	0	20	0	0.69872906	FALSE	0	ASB5	17984	0.08016591
793292	taxon:9606	2.57412951	2.36E-05	180367	1902	hydroxyacyl-CoA dehydrogenase	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0032868-&&-response to insulin-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0070403-&&-NAD+ binding-%%-GO:0003857-&&-3-hydroxyacyl-CoA dehydrogenase activity	G:9606:HADH			KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00650-&&-Butanoate metabolism-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	HADH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HADH	0.38848084	0.12418301	20	4	FALSE	HADH	HADH	217.3333333	0	19	0	0.73764508	FALSE	1	HADH	40214	0.07939409
793297	taxon:9606	2.7064755	1.89E-05	180357	1902	hemoglobin subunit beta	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0070293-&&-renal absorption-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0070527-&&-platelet aggregation-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0007596-&&-blood coagulation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:0030185-&&-nitric oxide transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0042744-&&-hydrogen peroxide catabolic process|cellular_component-&-1&-GO:0005833-&&-hemoglobin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0031838-&&-haptoglobin-hemoglobin complex-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0030492-&&-hemoglobin binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004601-&&-peroxidase activity-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0031720-&&-haptoglobin binding-%%-GO:0020037-&&-heme binding-%%-GO:0019825-&&-oxygen binding	G:9606:HBB	HBB	TRUE	KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa05144-&&-Malaria	HBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBB	0.36948422	0.11111111	20	4	FALSE	HBB	HBB	174.2222222	0	19	0	0.71558742	FALSE	1	HBB	28198	0.08937446
793305	taxon:9606	2.72869072	2.13E-05	180342	1902	hematopoietic cell-specific Lyn substrate 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0042993-&&-positive regulation of transcription factor import into nucleus-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0009725-&&-response to hormone-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:2000107-&&-negative regulation of leukocyte apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030854-&&-positive regulation of granulocyte differentiation-%%-GO:0042531-&&-positive regulation of tyrosine phosphorylation of STAT protein-%%-GO:0051897-&&-positive regulation of protein kinase B signaling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:HCLS1			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04530-&&-Tight junction-%%-hsa05131-&&-Shigellosis	HCLS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCLS1	0.36647612	0.09473684	20	4	FALSE	HCLS1	HCLS1	137.7	0	20	0	0.71188488	FALSE	0	HCLS1	26526	0.07657382
787021	taxon:9606	2.74523397	1.14E-05	180216	1902	integrin subunit beta 7	gene	biological_process-&-1&-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0043113-&&-receptor clustering-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0050776-&&-regulation of immune response-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0003366-&&-cell-matrix adhesion involved in ameboidal cell migration-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0072678-&&-T cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0043235-&&-receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0034669-&&-integrin alpha4-beta7 complex-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:ITGB7			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGB7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB7	0.36426768	0.13235294	19	5	FALSE	ITGB7	ITGB7	191.4117647	0	18	0	0.70912767	FALSE	1	ITGB7	21268	0.11382598
787081	taxon:9606	2.80305656	5.84E-05	180111	1902	insulin like growth factor binding protein 5	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0044342-&&-type B pancreatic cell proliferation-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0043569-&&-negative regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0051146-&&-striated muscle cell differentiation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0048286-&&-lung alveolus development-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0060056-&&-mammary gland involution-%%-GO:1904205-&&-negative regulation of skeletal muscle hypertrophy-%%-GO:0007165-&&-signal transduction-%%-GO:0007568-&&-aging-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0007565-&&-female pregnancy-%%-GO:1901862-&&-negative regulation of muscle tissue development-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0060416-&&-response to growth hormone-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005622-&&-intracellular-%%-GO:0016942-&&-insulin-like growth factor binding protein complex-%%-GO:0042567-&&-insulin-like growth factor ternary complex|molecular_function-&-1&-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0005515-&&-protein binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0001968-&&-fibronectin binding	G:9606:IGFBP5	IGFBP5	TRUE		IGFBP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP5	0.35675341	0.0994152	19	5	FALSE	IGFBP5	IGFBP5	89.73684211	0	19	0	0.69949057	FALSE	0	IGFBP5	53758	0.06666144
787094	taxon:9606	2.68898692	2.22E-04	180061	1902	interleukin 1 beta	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009743-&&-response to carbohydrate-%%-GO:0035690-&&-cellular response to drug-%%-GO:0000165-&&-MAPK cascade-%%-GO:0032308-&&-positive regulation of prostaglandin secretion-%%-GO:1903140-&&-regulation of establishment of endothelial barrier-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0031622-&&-positive regulation of fever generation-%%-GO:0032611-&&-interleukin-1 beta production-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0046827-&&-positive regulation of protein export from nucleus-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0035505-&&-positive regulation of myosin light chain kinase activity-%%-GO:0060355-&&-positive regulation of cell adhesion molecule production-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0050996-&&-positive regulation of lipid catabolic process-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045833-&&-negative regulation of lipid metabolic process-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0071639-&&-positive regulation of monocyte chemotactic protein-1 production-%%-GO:0006954-&&-inflammatory response-%%-GO:0032725-&&-positive regulation of granulocyte macrophage colony-stimulating factor production-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0060559-&&-positive regulation of calcidiol 1-monooxygenase activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0002711-&&-positive regulation of T cell mediated immunity-%%-GO:0014805-&&-smooth muscle adaptation-%%-GO:0033198-&&-response to ATP-%%-GO:0007165-&&-signal transduction-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0070164-&&-negative regulation of adiponectin secretion-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0070487-&&-monocyte aggregation-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0030213-&&-hyaluronan biosynthetic process-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0010829-&&-negative regulation of glucose transport-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0007566-&&-embryo implantation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0006955-&&-immune response-%%-GO:0030730-&&-sequestering of triglyceride-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001660-&&-fever generation-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005764-&&-lysosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0030141-&&-secretory granule|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005149-&&-interleukin-1 receptor binding-%%-GO:0005125-&&-cytokine activity	G:9606:IL1B	IL1B	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05010-&&-Alzheimer disease-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05020-&&-Prion diseases-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	IL1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1B	0.37188727	0.07352941	19	4	FALSE	IL1B	IL1B	155	0	18	0	0.71850218	FALSE	1	IL1B	198742	0.0759395
787139	taxon:9606	2.68457539	5.16E-05	179998	1902	insulin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045922-&&-negative regulation of fatty acid metabolic process-%%-GO:0045721-&&-negative regulation of gluconeogenesis-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0015758-&&-glucose transport-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0032460-&&-negative regulation of protein oligomerization-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0060266-&&-negative regulation of respiratory burst involved in inflammatory response-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:2000252-&&-negative regulation of feeding behavior-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0090336-&&-positive regulation of brown fat cell differentiation-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0006953-&&-acute-phase response-%%-GO:0046889-&&-positive regulation of lipid biosynthetic process-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process-%%-GO:0022898-&&-regulation of transmembrane transporter activity-%%-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:1902176-&&-negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0046631-&&-alpha-beta T cell activation-%%-GO:0033861-&&-negative regulation of NAD(P)H oxidase activity-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0050709-&&-negative regulation of protein secretion-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0042060-&&-wound healing-%%-GO:0045818-&&-negative regulation of glycogen catabolic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:0060267-&&-positive regulation of respiratory burst-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0055089-&&-fatty acid homeostasis|cellular_component-&-1&-GO:0005796-&&-Golgi lumen-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0030133-&&-transport vesicle-%%-GO:0031904-&&-endosome lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0000139-&&-Golgi membrane-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0002020-&&-protease binding	G:9606:INS	INS	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04950-&&-Maturity onset diabetes of the young-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa04022-&&-cGMP-PKG signaling pathway	INS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INS	0.37249839	0.07352941	19	4	FALSE	INS	INS	151.8235294	0	18	0	0.71923744	FALSE	1	INS	58180	0.07429429
787249	taxon:9606	2.59476918	4.80E-05	179803	1902	ISL LIM homeobox 1	gene	biological_process-&-1&-GO:0032730-&&-positive regulation of interleukin-1 alpha production-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0031016-&&-pancreas development-%%-GO:0060384-&&-innervation-%%-GO:0021520-&&-spinal cord motor neuron cell fate specification-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0031103-&&-axon regeneration-%%-GO:0032731-&&-positive regulation of interleukin-1 beta production-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0021559-&&-trigeminal nerve development-%%-GO:0003266-&&-regulation of secondary heart field cardioblast proliferation-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0060379-&&-cardiac muscle cell myoblast differentiation-%%-GO:0090074-&&-negative regulation of protein homodimerization activity-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0071657-&&-positive regulation of granulocyte colony-stimulating factor production-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0021524-&&-visceral motor neuron differentiation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0048936-&&-peripheral nervous system neuron axonogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021522-&&-spinal cord motor neuron differentiation-%%-GO:0032725-&&-positive regulation of granulocyte macrophage colony-stimulating factor production-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0003139-&&-secondary heart field specification-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0021983-&&-pituitary gland development-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0048880-&&-sensory system development-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0060913-&&-cardiac cell fate determination-%%-GO:0048665-&&-neuron fate specification-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:1901258-&&-positive regulation of macrophage colony-stimulating factor production-%%-GO:0060413-&&-atrial septum morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0030331-&&-estrogen receptor binding	G:9606:ISL1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	ISL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISL1	0.38539073	0.11764706	19	4	FALSE	ISL1	ISL1	229.8235294	0	18	0	0.73420514	FALSE	1	ISL1	47802	0.08770707
787301	taxon:9606	2.69670711	1.98E-04	179697	1902	kallikrein related peptidase 2	gene	biological_process-&-1&-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity	G:9606:KLK2			KEGG-&-1&-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04614-&&-Renin-angiotensin system	KLK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK2	0.37082262	0.05847953	19	5	FALSE	KLK2	KLK2	143.8421053	0	19	0	0.71721548	FALSE	0	KLK2	173560	0.07061598
787340	taxon:9606	2.86103671	1.93E-05	179624	1902	laminin subunit beta 3	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005610-&&-laminin-5 complex|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:LAMB3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	LAMB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMB3	0.34952365	0.07602339	19	4	FALSE	LAMB3	LAMB3	77.78947368	0	19	0	0.68982721	FALSE	0	LAMB3	18574	0.07397549
787426	taxon:9606	2.80541988	9.03E-06	179452	1902	lactate dehydrogenase C	gene	biological_process-&-1&-GO:0030317-&&-flagellated sperm motility-%%-GO:0019516-&&-lactate oxidation-%%-GO:0006090-&&-pyruvate metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0006754-&&-ATP biosynthetic process-%%-GO:0019244-&&-lactate biosynthetic process from pyruvate|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031514-&&-motile cilium|molecular_function-&-1&-GO:0004459-&&-L-lactate dehydrogenase activity	G:9606:LDHC			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00640-&&-Propanoate metabolism	LDHC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDHC	0.35645288	0.11111111	19	4	FALSE	LDHC	LDHC	108.5789474	0	19	0	0.69909669	FALSE	0	LDHC	17006	0.07997669
787477	taxon:9606	2.67228612	5.23E-06	162972	1902	TGF-beta activated kinase 1 and MAP3K7 binding protein 3	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0070423-&&-nucleotide-binding oligomerization domain containing signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TAB3			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway	TAB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAB3	0.37421143	0.38970588	19	4	FALSE	TAB3	TAB3	211.5882353	0	18	0	0.72128565	FALSE	1	TAB3	11060	0.09882683
787552	taxon:9606	2.77422404	2.29E-05	179203	1902	msh homeobox 1	gene	biological_process-&-1&-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0007517-&&-muscle organ development-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0051154-&&-negative regulation of striated muscle cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0050821-&&-protein stabilization-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0021983-&&-pituitary gland development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:1902255-&&-positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:2001055-&&-positive regulation of mesenchymal cell apoptotic process-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0030901-&&-midbrain development-%%-GO:0042481-&&-regulation of odontogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010463-&&-mesenchymal cell proliferation-%%-GO:0060021-&&-palate development-%%-GO:0061312-&&-BMP signaling pathway involved in heart development-%%-GO:0090427-&&-activation of meiosis-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060325-&&-face morphogenesis-%%-GO:0061180-&&-mammary gland epithelium development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0035880-&&-embryonic nail plate morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0002039-&&-p53 binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:MSX1			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	MSX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSX1	0.36046115	0.19852941	19	4	FALSE	MSX1	MSX1	147.2941177	0	18	0	0.70429599	FALSE	1	MSX1	25544	0.09213723
787553	taxon:9606	2.85741295	1.15E-05	179202	1902	msh homeobox 2	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:0002063-&&-chondrocyte development-%%-GO:0060364-&&-frontal suture morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0002076-&&-osteoblast development-%%-GO:0051795-&&-positive regulation of catagen-%%-GO:0070166-&&-enamel mineralization-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:2001055-&&-positive regulation of mesenchymal cell apoptotic process-%%-GO:0032792-&&-negative regulation of CREB transcription factor activity-%%-GO:0003416-&&-endochondral bone growth-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0061312-&&-BMP signaling pathway involved in heart development-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0060363-&&-cranial suture morphogenesis-%%-GO:0090427-&&-activation of meiosis-%%-GO:2000678-&&-negative regulation of transcription regulatory region DNA binding-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045617-&&-negative regulation of keratinocyte differentiation-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0060346-&&-bone trabecula formation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035880-&&-embryonic nail plate morphogenesis-%%-GO:0045599-&&-negative regulation of fat cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:MSX2			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	MSX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSX2	0.34996692	0.14705882	19	5	FALSE	MSX2	MSX2	95.47058824	0	18	0	0.69043117	FALSE	1	MSX2	14436	0.08859031
787559	taxon:9606	2.73798645	2.15E-05	162793	1902	homeodomain interacting protein kinase 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0034333-&&-adherens junction assembly-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030182-&&-neuron differentiation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0060235-&&-lens induction in camera-type eye-%%-GO:0061072-&&-iris morphogenesis-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0010842-&&-retina layer formation-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001654-&&-eye development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007224-&&-smoothened signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:HIPK1			KEGG-&-1&-hsa04218-&&-Cellular senescence	HIPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIPK1	0.3652319	0.09356725	19	4	FALSE	HIPK1	HIPK1	131.1578947	0	19	0	0.71033559	FALSE	0	HIPK1	29052	0.07405972
787673	taxon:9606	2.48448086	1.47E-05	178972	1902	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta	gene	biological_process-&-1&-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0008150-&&-biological_process-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:1905037-&&-autophagosome organization|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030139-&&-endocytic vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0001727-&&-lipid kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:PIK3C2B			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PIK3C2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3C2B	0.40249857	0.38011696	19	4	FALSE	PIK3C2B	PIK3C2B	368.1578947	0	19	0	0.75258652	FALSE	0	PIK3C2B	28066	0.11149543
787851	taxon:9606	2.79123996	8.20E-06	145954	1902	coiled-coil domain containing 180	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:CCDC180				CCDC180	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC180	0.35826372	0.06432749	19	4	FALSE	CCDC180	CCDC180	121.2631579	0	19	0	0.70146001	FALSE	0	CCDC180	20384	0.08354854
787853	taxon:9606	2.71876477	1.88E-05	162328	1902	mitogen-activated protein kinase 15	gene	biological_process-&-1&-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0000165-&&-MAPK cascade-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005515-&&-protein binding	G:9606:MAPK15			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	MAPK15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK15	0.36781409	0.08088235	19	5	FALSE	MAPK15	MAPK15	160.5882353	0	18	0	0.7135392	FALSE	1	MAPK15	25340	0.08541628
787855	taxon:9606	2.65322199	1.82E-05	178709	1902	prospero homeobox 1	gene	biological_process-&-1&-GO:0070309-&&-lens fiber cell morphogenesis-%%-GO:0055005-&&-ventricular cardiac myofibril assembly-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0030182-&&-neuron differentiation-%%-GO:2000979-&&-positive regulation of forebrain neuron differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001822-&&-kidney development-%%-GO:0070858-&&-negative regulation of bile acid biosynthetic process-%%-GO:0060414-&&-aorta smooth muscle tissue morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0021915-&&-neural tube development-%%-GO:0031016-&&-pancreas development-%%-GO:0001709-&&-cell fate determination-%%-GO:0007420-&&-brain development-%%-GO:0043049-&&-otic placode formation-%%-GO:1901978-&&-positive regulation of cell cycle checkpoint-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0060059-&&-embryonic retina morphogenesis in camera-type eye-%%-GO:0060214-&&-endocardium formation-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0060849-&&-regulation of transcription involved in lymphatic endothelial cell fate commitment-%%-GO:0030240-&&-skeletal muscle thin filament assembly-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060042-&&-retina morphogenesis in camera-type eye-%%-GO:0030910-&&-olfactory placode formation-%%-GO:0060421-&&-positive regulation of heart growth-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060836-&&-lymphatic endothelial cell differentiation-%%-GO:0002194-&&-hepatocyte cell migration-%%-GO:0030324-&&-lung development-%%-GO:0072574-&&-hepatocyte proliferation-%%-GO:0021707-&&-cerebellar granule cell differentiation-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0046619-&&-optic placode formation involved in camera-type eye formation-%%-GO:0090425-&&-acinar cell differentiation-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0001889-&&-liver development-%%-GO:0055009-&&-atrial cardiac muscle tissue morphogenesis-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0061114-&&-branching involved in pancreas morphogenesis-%%-GO:0007623-&&-circadian rhythm-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0021516-&&-dorsal spinal cord development-%%-GO:0048845-&&-venous blood vessel morphogenesis-%%-GO:0060298-&&-positive regulation of sarcomere organization-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0050693-&&-LBD domain binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0050692-&&-DBD domain binding-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:PROX1				PROX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PROX1	0.37690024	0.15204678	19	4	FALSE	PROX1	PROX1	180.6842105	0	19	0	0.724463	FALSE	0	PROX1	33342	0.07888989
787921	taxon:9606	2.77658736	8.56E-05	178610	1902	parathyroid hormone 1 receptor	gene	biological_process-&-1&-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0048469-&&-cell maturation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045453-&&-bone resorption-%%-GO:0030282-&&-bone mineralization-%%-GO:0002076-&&-osteoblast development-%%-GO:0007568-&&-aging-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0001501-&&-skeletal system development-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0060732-&&-positive regulation of inositol phosphate biosynthetic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0031526-&&-brush border membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043235-&&-receptor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0005515-&&-protein binding-%%-GO:0004991-&&-parathyroid hormone receptor activity-%%-GO:0017046-&&-peptide hormone binding	G:9606:PTH1R			KEGG-&-1&-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	PTH1R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTH1R	0.36015434	0.04093567	19	4	FALSE	PTH1R	PTH1R	100.4736842	0	19	0	0.70390211	FALSE	0	PTH1R	88406	0.06605907
787943	taxon:9606	2.62990389	1.15E-05	178534	1902	poly(A) binding protein cytoplasmic 3	gene	biological_process-&-1&-GO:0016071-&&-mRNA metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008143-&&-poly(A) binding	G:9606:PABPC3			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa03018-&&-RNA degradation	PABPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC3	0.38024203	0.12280702	19	4	FALSE	PABPC3	PABPC3	212.2105263	0	19	0	0.72834935	FALSE	0	PABPC3	26540	0.08843597
787945	taxon:9606	2.82164802	4.69E-05	178531	1902	furin, paired basic amino acid cleaving enzyme	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0045714-&&-regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0019058-&&-viral life cycle-%%-GO:0032804-&&-negative regulation of low-density lipoprotein particle receptor catabolic process-%%-GO:0016486-&&-peptide hormone processing-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006465-&&-signal peptide processing-%%-GO:0008283-&&-cell proliferation-%%-GO:0032455-&&-nerve growth factor processing-%%-GO:0032911-&&-negative regulation of transforming growth factor beta1 production-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0052548-&&-regulation of endopeptidase activity-%%-GO:0016485-&&-protein processing-%%-GO:0019082-&&-viral protein processing-%%-GO:0070268-&&-cornification-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0032902-&&-nerve growth factor production-%%-GO:0032904-&&-negative regulation of nerve growth factor production-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0043043-&&-peptide biosynthetic process-%%-GO:0032940-&&-secretion by cell|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0009986-&&-cell surface-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0048406-&&-nerve growth factor binding	G:9606:FURIN			KEGG-&-1&-hsa05164-&&-Influenza A	FURIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FURIN	0.35440281	0.03676471	19	4	FALSE	FURIN	FURIN	90.94117647	0	18	0	0.696392	FALSE	1	FURIN	44904	0.07380552
787970	taxon:9606	2.76965496	3.21E-05	178486	1902	protocadherin 7	gene	biological_process-&-1&-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:PCDH7				PCDH7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCDH7	0.36105581	0.01754386	19	4	FALSE	PCDH7	PCDH7	110.7894737	0	19	0	0.70505751	FALSE	0	PCDH7	37438	0.07104753
787987	taxon:9606	2.90720025	2.02E-05	178445	1902	phosphodiesterase 9A	gene	biological_process-&-1&-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0046068-&&-cGMP metabolic process-%%-GO:0046069-&&-cGMP catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0019934-&&-cGMP-mediated signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0042383-&&-sarcolemma-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0032587-&&-ruffle membrane-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0047555-&&-3',5'-cyclic-GMP phosphodiesterase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004114-&&-3',5'-cyclic-nucleotide phosphodiesterase activity-%%-GO:0005515-&&-protein binding	G:9606:PDE9A			KEGG-&-1&-hsa00230-&&-Purine metabolism	PDE9A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE9A	0.34397355	0.16911765	19	5	FALSE	PDE9A	PDE9A	81.88235294	0	18	0	0.68213329	FALSE	1	PDE9A	22336	0.09184146
788075	taxon:9606	2.72774539	1.28E-05	178277	1902	ribosomal protein L36a like	gene	biological_process-&-1&-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL36AL			KEGG-&-1&-hsa03010-&&-Ribosome	RPL36AL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL36AL	0.36660313	0.28070175	19	5	FALSE	RPL36AL	RPL36AL	182.2105263	0	19	0	0.71204243	FALSE	0	RPL36AL	22060	0.1
788246	taxon:9606	2.83645817	1.10E-05	145241	1902	RAB4B-EGLN2 readthrough (NMD candidate)	gene		G:9606:RAB4B-EGLN2				RAB4B-EGLN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB4B-EGLN2	0.35255235	0.20588235	19	5	FALSE	RAB4B-EGLN2	RAB4B-EGLN2	92.23529412	0	18	0	0.69392364	FALSE	1	RAB4B-EGLN2	16364	0.07724899
788304	taxon:9606	2.6037498	1.55E-05	177923	1902	Ras suppressor protein 1	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0010810-&&-regulation of cell-substrate adhesion|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RSU1				RSU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RSU1	0.38406148	0.12865497	19	4	FALSE	RSU1	RSU1	205.5789474	0	19	0	0.73270837	FALSE	0	RSU1	26888	0.08043111
788360	taxon:9606	2.85631007	1.52E-05	177810	1902	syndecan 4	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0010762-&&-regulation of fibroblast migration-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0007165-&&-signal transduction-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0001657-&&-ureteric bud development-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0001843-&&-neural tube closure-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:1903553-&&-positive regulation of extracellular exosome assembly-%%-GO:0042060-&&-wound healing-%%-GO:0060122-&&-inner ear receptor stereocilium organization|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043034-&&-costamere-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005925-&&-focal adhesion-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0001968-&&-fibronectin binding-%%-GO:0005515-&&-protein binding-%%-GO:0070053-&&-thrombospondin receptor activity-%%-GO:0005080-&&-protein kinase C binding	G:9606:SDC4			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis	SDC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDC4	0.35010205	0.08088235	19	4	FALSE	SDC4	SDC4	80.94117647	0	18	0	0.69061499	FALSE	1	SDC4	17654	0.07739641
788385	taxon:9606	2.84732945	5.61E-05	177757	1902	suppression of tumorigenicity 14	gene	biological_process-&-1&-GO:0060672-&&-epithelial cell morphogenesis involved in placental branching-%%-GO:0001843-&&-neural tube closure-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0070268-&&-cornification-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004175-&&-endopeptidase activity	G:9606:ST14			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	ST14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ST14	0.35120629	0.03676471	19	4	FALSE	ST14	ST14	79.82352941	0	18	0	0.69211176	FALSE	1	ST14	43948	0.07445457
788445	taxon:9606	2.73830156	1.14E-05	177666	1902	Src like adaptor	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:SLA				SLA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLA	0.36518987	0.23529412	19	5	FALSE	SLA	SLA	155.4117647	0	18	0	0.71028307	FALSE	1	SLA	19382	0.08916444
788455	taxon:9606	2.83047109	1.36E-05	177639	1902	solute carrier family 6 member 3	gene	biological_process-&-1&-GO:0035094-&&-response to nicotine-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0015844-&&-monoamine transport-%%-GO:0042053-&&-regulation of dopamine metabolic process-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0007595-&&-lactation-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0007568-&&-aging-%%-GO:0045471-&&-response to ethanol-%%-GO:0010039-&&-response to iron ion-%%-GO:0007626-&&-locomotory behavior-%%-GO:0042420-&&-dopamine catabolic process-%%-GO:0051591-&&-response to cAMP-%%-GO:0090494-&&-dopamine uptake-%%-GO:0042493-&&-response to drug-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0015872-&&-dopamine transport-%%-GO:0060134-&&-prepulse inhibition-%%-GO:0072488-&&-ammonium transmembrane transport-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0045121-&&-membrane raft-%%-GO:0016600-&&-flotillin complex-%%-GO:0030424-&&-axon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0043025-&&-neuronal cell body-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0035240-&&-dopamine binding-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0008504-&&-monoamine transmembrane transporter activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0051721-&&-protein phosphatase 2A binding-%%-GO:0002020-&&-protease binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005329-&&-dopamine transmembrane transporter activity-%%-GO:0005330-&&-dopamine:sodium symporter activity-%%-GO:0005102-&&-receptor binding	G:9606:SLC6A3	SLC6A3	TRUE	KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05012-&&-Parkinson disease-%%-hsa05034-&&-Alcoholism-%%-hsa05030-&&-Cocaine addiction-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05031-&&-Amphetamine addiction	SLC6A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC6A3	0.35329808	0.11764706	19	4	FALSE	SLC6A3	SLC6A3	96.64705882	0	18	0	0.69492149	FALSE	1	SLC6A3	15104	0.08047727
788673	taxon:9606	2.72616984	1.28E-05	177217	1902	NK2 homeobox 1	gene	biological_process-&-1&-GO:0030878-&&-thyroid gland development-%%-GO:0060486-&&-Clara cell differentiation-%%-GO:0007492-&&-endoderm development-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0060430-&&-lung saccule development-%%-GO:0009725-&&-response to hormone-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060510-&&-Type II pneumocyte differentiation-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007411-&&-axon guidance-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007626-&&-locomotory behavior-%%-GO:0021759-&&-globus pallidus development-%%-GO:0031128-&&-developmental induction-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0030324-&&-lung development-%%-GO:0021877-&&-forebrain neuron fate commitment-%%-GO:0042753-&&-positive regulation of circadian rhythm-%%-GO:0007420-&&-brain development-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0021798-&&-forebrain dorsal/ventral pattern formation-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030900-&&-forebrain development-%%-GO:0021983-&&-pituitary gland development-%%-GO:0048511-&&-rhythmic process-%%-GO:0021892-&&-cerebral cortex GABAergic interneuron differentiation|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0044213-&&-intronic transcription regulatory region DNA binding-%%-GO:0001161-&&-intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0001012-&&-RNA polymerase II regulatory region DNA binding	G:9606:NKX2-1				NKX2-1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKX2-1	0.366815	0.23391813	19	4	FALSE	NKX2-1	NKX2-1	184.4736842	0	19	0	0.71230503	FALSE	0	NKX2-1	24876	0.10253932
788683	taxon:9606	2.81849693	1.09E-05	177200	1902	toll like receptor 3	gene	biological_process-&-1&-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006972-&&-hyperosmotic response-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:0045356-&&-positive regulation of interferon-alpha biosynthetic process-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0097527-&&-necroptotic signaling pathway-%%-GO:0034346-&&-positive regulation of type III interferon production-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0034128-&&-negative regulation of MyD88-independent toll-like receptor signaling pathway-%%-GO:0045078-&&-positive regulation of interferon-gamma biosynthetic process-%%-GO:0071360-&&-cellular response to exogenous dsRNA-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity-%%-GO:0035666-&&-TRIF-dependent toll-like receptor signaling pathway-%%-GO:0070266-&&-necroptotic process-%%-GO:0002730-&&-regulation of dendritic cell cytokine production-%%-GO:0006954-&&-inflammatory response-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0002756-&&-MyD88-independent toll-like receptor signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0045359-&&-positive regulation of interferon-beta biosynthetic process-%%-GO:0007252-&&-I-kappaB phosphorylation-%%-GO:0034138-&&-toll-like receptor 3 signaling pathway-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0009597-&&-detection of virus-%%-GO:0045087-&&-innate immune response-%%-GO:0035690-&&-cellular response to drug-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0002282-&&-microglial cell activation involved in immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0008584-&&-male gonad development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0034123-&&-positive regulation of toll-like receptor signaling pathway-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005769-&&-early endosome-%%-GO:0009986-&&-cell surface-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0003725-&&-double-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004872-&&-receptor activity	G:9606:TLR3			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05165-&&-Human papillomavirus infection	TLR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLR3	0.35479904	0.22058824	19	5	FALSE	TLR3	TLR3	117.3529412	0	18	0	0.69691718	FALSE	1	TLR3	13672	0.09202142
788717	taxon:9606	2.6417205	1.85E-05	177130	1902	tripeptidyl peptidase 2	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0008240-&&-tripeptidyl-peptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004177-&&-aminopeptidase activity	G:9606:TPP2				TPP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPP2	0.37854118	0.0877193	19	4	FALSE	TPP2	TPP2	236.6842105	0	19	0	0.72637992	FALSE	0	TPP2	34752	0.10034641
788727	taxon:9606	2.62722546	1.56E-05	177104	1902	trio Rho guanine nucleotide exchange factor	gene	biological_process-&-1&-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:TRIO				TRIO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIO	0.38062969	0.11695906	19	4	FALSE	TRIO	TRIO	203.0526316	0	19	0	0.72879576	FALSE	0	TRIO	29138	0.08366793
788765	taxon:9606	2.80053569	7.72E-06	176978	1902	zinc finger protein 189	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF189				ZNF189	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF189	0.35707454	0.06432749	19	5	FALSE	ZNF189	ZNF189	119.5263158	0	19	0	0.69991072	FALSE	0	ZNF189	18002	0.085136
788775	taxon:9606	2.74113755	6.96E-05	176927	1902	BTG anti-proliferation factor 2	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0008306-&&-associative learning-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0060213-&&-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0006281-&&-DNA repair-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031175-&&-neuron projection development-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0051602-&&-response to electrical stimulus|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:BTG2			KEGG-&-1&-hsa03018-&&-RNA degradation	BTG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTG2	0.36481205	0.12865497	19	5	FALSE	BTG2	BTG2	134.5263158	0	19	0	0.70981041	FALSE	0	BTG2	74128	0.07790939
788937	taxon:9606	2.76477076	1.57E-05	176563	1902	forkhead box N1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0008544-&&-epidermis development-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:1902232-&&-regulation of positive thymic T cell selection-%%-GO:0002360-&&-T cell lineage commitment-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0001942-&&-hair follicle development-%%-GO:0030858-&&-positive regulation of epithelial cell differentiation-%%-GO:0035878-&&-nail development-%%-GO:0097536-&&-thymus epithelium morphogenesis-%%-GO:0051798-&&-positive regulation of hair follicle development-%%-GO:0097535-&&-lymphoid lineage cell migration into thymus-%%-GO:0006952-&&-defense response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:FOXN1				FOXN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXN1	0.36169364	0.09356725	19	4	FALSE	FOXN1	FOXN1	126.3157895	0	19	0	0.70587154	FALSE	0	FOXN1	25144	0.07817962
788994	taxon:9606	2.51315582	1.18E-04	176433	1902	aladin WD repeat nucleoporin	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0007612-&&-learning-%%-GO:0016925-&&-protein sumoylation-%%-GO:0006409-&&-tRNA export from nucleus-%%-GO:0046822-&&-regulation of nucleocytoplasmic transport-%%-GO:0009566-&&-fertilization-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0019083-&&-viral transcription-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0016032-&&-viral process-%%-GO:1900034-&&-regulation of cellular response to heat-%%-GO:0007077-&&-mitotic nuclear envelope disassembly|cellular_component-&-1&-GO:0005643-&&-nuclear pore-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:AAAS			KEGG-&-1&-hsa03013-&&-RNA transport	AAAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AAAS	0.39790609	0.14035088	19	4	FALSE	AAAS	AAAS	319.3684211	0	19	0	0.74780736	FALSE	0	AAAS	134312	0.10203154
789002	taxon:9606	2.90830314	3.69E-06	176417	1902	double PHD fingers 3	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0071565-&&-nBAF complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0008270-&&-zinc ion binding	G:9606:DPF3			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	DPF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPF3	0.34384311	0.52631579	19	4	FALSE	DPF3	DPF3	94.36842105	0	19	0	0.68194948	FALSE	0	DPF3	5906	0.11181093
789206	taxon:9606	2.67307389	7.19E-05	176006	1902	diacylglycerol kinase zeta	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0046486-&&-glycerolipid metabolic process-%%-GO:0030168-&&-platelet activation-%%-GO:0046834-&&-lipid phosphorylation-%%-GO:0016477-&&-cell migration-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0046339-&&-diacylglycerol metabolic process|cellular_component-&-1&-GO:0030027-&&-lamellipodium-%%-GO:0005886-&&-plasma membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016301-&&-kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004143-&&-diacylglycerol kinase activity-%%-GO:0005515-&&-protein binding	G:9606:DGKZ			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway	DGKZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DGKZ	0.37410114	0.05847953	19	4	FALSE	DGKZ	DGKZ	169.2105263	0	19	0	0.72115435	FALSE	0	DGKZ	70366	0.079182
789264	taxon:9606	2.7496455	1.40E-05	175873	1902	phosphoprotein enriched in astrocytes 15	gene	biological_process-&-1&-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0043278-&&-response to morphine-%%-GO:0006915-&&-apoptotic process-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0000077-&&-DNA damage checkpoint-%%-GO:0008643-&&-carbohydrate transport-%%-GO:0006810-&&-transport-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005875-&&-microtubule associated complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PEA15				PEA15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEA15	0.36368325	0.09356725	19	4	FALSE	PEA15	PEA15	130.3157895	0	19	0	0.70839242	FALSE	0	PEA15	23928	0.0777991
789305	taxon:9606	2.76634631	1.28E-04	175786	1902	eukaryotic translation initiation factor 2 alpha kinase 3	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0031642-&&-negative regulation of myelination-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032057-&&-negative regulation of translational initiation in response to stress-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1902235-&&-regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1990737-&&-response to manganese-induced endoplasmic reticulum stress-%%-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0070417-&&-cellular response to cold-%%-GO:0001501-&&-skeletal system development-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0036492-&&-eiF2alpha phosphorylation in response to endoplasmic reticulum stress-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0001525-&&-angiogenesis-%%-GO:0001503-&&-ossification-%%-GO:0030282-&&-bone mineralization-%%-GO:0002063-&&-chondrocyte development-%%-GO:0045943-&&-positive regulation of transcription from RNA polymerase I promoter-%%-GO:0010998-&&-regulation of translational initiation by eIF2 alpha phosphorylation-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006983-&&-ER overload response-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0030073-&&-insulin secretion-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0060734-&&-regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0007029-&&-endoplasmic reticulum organization|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0004694-&&-eukaryotic translation initiation factor 2alpha kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:EIF2AK3	EIF2AK3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04140-&&-Autophagy - animal-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa05160-&&-Hepatitis C-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	EIF2AK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2AK3	0.36148764	0.05882353	19	4	FALSE	EIF2AK3	EIF2AK3	126.5294118	0	18	0	0.70560895	FALSE	1	EIF2AK3	142134	0.08058636
789388	taxon:9606	2.52686308	2.54E-05	175598	1902	NUMB like, endocytic adaptor protein	gene	biological_process-&-1&-GO:0021849-&&-neuroblast division in subventricular zone-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0019538-&&-protein metabolic process-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0007399-&&-nervous system development-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0034332-&&-adherens junction organization-%%-GO:0007409-&&-axonogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NUMBL			KEGG-&-1&-hsa04330-&&-Notch signaling pathway	NUMBL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUMBL	0.3957476	0.12280702	19	4	FALSE	NUMBL	NUMBL	260.4210526	0	19	0	0.74552282	FALSE	0	NUMBL	38248	0.08570834
789429	taxon:9606	2.71088703	1.04E-04	175501	1902	signal peptidase complex subunit 2	gene	biological_process-&-1&-GO:0045047-&&-protein targeting to ER-%%-GO:0006465-&&-signal peptide processing|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005787-&&-signal peptidase complex-%%-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008233-&&-peptidase activity	G:9606:SPCS2			KEGG-&-1&-hsa03060-&&-Protein export	SPCS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPCS2	0.36888295	0.02923977	19	4	FALSE	SPCS2	SPCS2	146.5263158	0	19	0	0.71485216	FALSE	0	SPCS2	91450	0.07564425
789477	taxon:9606	2.67212856	1.57E-05	175376	1902	Ras and Rab interactor 1	gene	biological_process-&-1&-GO:0007613-&&-memory-%%-GO:0061024-&&-membrane organization-%%-GO:0006897-&&-endocytosis-%%-GO:0008306-&&-associative learning-%%-GO:0007165-&&-signal transduction-%%-GO:0031914-&&-negative regulation of synaptic plasticity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030425-&&-dendrite-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0017016-&&-Ras GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RIN1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	RIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIN1	0.37423349	0.1754386	19	4	FALSE	RIN1	RIN1	185.8947368	0	19	0	0.72131191	FALSE	0	RIN1	26476	0.0861244
789493	taxon:9606	2.54135812	7.96E-06	175340	1902	tetratricopeptide repeat domain 37	gene	biological_process-&-1&-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0035327-&&-transcriptionally active chromatin-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0055087-&&-Ski complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TTC37			KEGG-&-1&-hsa03018-&&-RNA degradation	TTC37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC37	0.39349039	0.26315789	19	4	FALSE	TTC37	TTC37	354.3157895	0	19	0	0.74310698	FALSE	0	TTC37	22924	0.11976933
789502	taxon:9606	2.56436112	1.06E-04	175325	1902	importin 13	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0008536-&&-Ran GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008139-&&-nuclear localization sequence binding	G:9606:IPO13				IPO13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IPO13	0.38996068	0.0877193	19	4	FALSE	IPO13	IPO13	240.1578947	0	19	0	0.73927315	FALSE	0	IPO13	108628	0.0855357
789536	taxon:9606	2.61225776	2.30E-05	175239	1902	ADP ribosylation factor guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0010256-&&-endomembrane system organization-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0031175-&&-neuron projection development-%%-GO:2000114-&&-regulation of establishment of cell polarity-%%-GO:0007030-&&-Golgi organization-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0090284-&&-positive regulation of protein glycosylation in Golgi-%%-GO:0006887-&&-exocytosis|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0030532-&&-small nuclear ribonucleoprotein complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016363-&&-nuclear matrix|molecular_function-&-1&-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0017022-&&-myosin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARFGEF1			KEGG-&-1&-hsa04144-&&-Endocytosis	ARFGEF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGEF1	0.38281062	0.11695906	19	4	FALSE	ARFGEF1	ARFGEF1	205.6842105	0	19	0	0.73129037	FALSE	0	ARFGEF1	37824	0.08179685
789602	taxon:9606	2.92342839	2.28E-05	175087	1902	Rho GTPase activating protein 25	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity	G:9606:ARHGAP25				ARHGAP25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP25	0.34206413	0.01169591	19	5	FALSE	ARHGAP25	ARHGAP25	47.47368421	0	19	0	0.6794286	FALSE	0	ARHGAP25	17376	0.06110499
789786	taxon:9606	2.72254608	1.99E-05	174677	1902	tripartite motif containing 13	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0045087-&&-innate immune response-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0032897-&&-negative regulation of viral transcription-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:1902187-&&-negative regulation of viral release from host cell-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0010332-&&-response to gamma radiation|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0097038-&&-perinuclear endoplasmic reticulum|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0008270-&&-zinc ion binding	G:9606:TRIM13				TRIM13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM13	0.36730324	0.10294118	19	4	FALSE	TRIM13	TRIM13	165	0	18	0	0.71290899	FALSE	1	TRIM13	28788	0.08998619
789828	taxon:9606	2.87647708	1.24E-05	174554	1902	thioredoxin like 4A	gene	biological_process-&-1&-GO:0000245-&&-spliceosomal complex assembly-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0000375-&&-RNA splicing, via transesterification reactions|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0046540-&&-U4/U6 x U5 tri-snRNP complex-%%-GO:0005829-&&-cytosol-%%-GO:0005681-&&-spliceosomal complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005682-&&-U5 snRNP|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TXNL4A			KEGG-&-1&-hsa03040-&&-Spliceosome	TXNL4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNL4A	0.34764748	0.05847953	19	4	FALSE	TXNL4A	TXNL4A	75.26315789	0	19	0	0.68725382	FALSE	0	TXNL4A	14596	0.07541558
789997	taxon:9606	2.53757681	2.12E-05	174155	1902	intestinal cell kinase	gene	biological_process-&-1&-GO:0035721-&&-intraciliary retrograde transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0035720-&&-intraciliary anterograde transport-%%-GO:0007275-&&-multicellular organism development-%%-GO:0042073-&&-intraciliary transport-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0097542-&&-ciliary tip-%%-GO:0097546-&&-ciliary base-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:ICK				ICK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICK	0.39407674	0.12865497	19	4	FALSE	ICK	ICK	241.3684211	0	19	0	0.7437372	FALSE	0	ICK	41552	0.08161812
790102	taxon:9606	2.67669765	2.60E-05	173869	1902	F-box protein 28	gene	cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBXO28				FBXO28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO28	0.37359468	0.10526316	19	4	FALSE	FBXO28	FBXO28	163.8421053	0	19	0	0.72055039	FALSE	0	FBXO28	29498	0.07715988
790139	taxon:9606	2.78604065	1.25E-05	173791	1902	microtubule associated protein RP/EB family member 3	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:1903033-&&-positive regulation of microtubule plus-end binding-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0035371-&&-microtubule plus-end-%%-GO:0030496-&&-midbody-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MAPRE3				MAPRE3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPRE3	0.35893231	0.08187135	19	4	FALSE	MAPRE3	MAPRE3	110.3684211	0	19	0	0.70232656	FALSE	0	MAPRE3	18758	0.0745614
790232	taxon:9606	2.5835828	1.85E-05	173570	1902	calmodulin regulated spectrin associated protein family member 2	gene	biological_process-&-1&-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0031175-&&-neuron projection development-%%-GO:0033043-&&-regulation of organelle organization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:1990752-&&-microtubule end|molecular_function-&-1&-GO:0030507-&&-spectrin binding-%%-GO:0051011-&&-microtubule minus-end binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:CAMSAP2				CAMSAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMSAP2	0.3870594	0.19883041	19	4	FALSE	CAMSAP2	CAMSAP2	237.2631579	0	19	0	0.73606953	FALSE	0	CAMSAP2	36044	0.08759621
790237	taxon:9606	2.75642036	9.45E-06	173552	1902	BICD cargo adaptor 2	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0051028-&&-mRNA transport-%%-GO:0000042-&&-protein targeting to Golgi-%%-GO:0051642-&&-centrosome localization-%%-GO:0072393-&&-microtubule anchoring at microtubule organizing center-%%-GO:0072385-&&-minus-end-directed organelle transport along microtubule|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005643-&&-nuclear pore-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005642-&&-annulate lamellae-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0051959-&&-dynein light intermediate chain binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0070840-&&-dynein complex binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:BICD2				BICD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BICD2	0.36278937	0.20588235	19	4	FALSE	BICD2	BICD2	144.0588235	0	18	0	0.70726327	FALSE	1	BICD2	14490	0.08537436
790268	taxon:9606	2.88766346	5.66E-06	173479	1902	mediator complex subunit 13 like	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016592-&&-mediator complex|molecular_function-&-1&-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:MED13L			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED13L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED13L	0.34630074	0.63157895	19	5	FALSE	MED13L	MED13L	89.68421053	0	19	0	0.68538942	FALSE	0	MED13L	8336	0.09202421
790306	taxon:9606	2.56956042	2.49E-05	173371	1902	component of oligomeric golgi complex 4	gene	biological_process-&-1&-GO:0000301-&&-retrograde transport, vesicle recycling within Golgi-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0015031-&&-protein transport-%%-GO:0048213-&&-Golgi vesicle prefusion complex stabilization-%%-GO:0007030-&&-Golgi organization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COG4				COG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG4	0.38917162	0.23976608	19	4	FALSE	COG4	COG4	228.7894737	0	19	0	0.7384066	FALSE	0	COG4	33254	0.0825169
790326	taxon:9606	2.55238695	1.52E-05	173310	1902	nucleolar protein 11	gene	biological_process-&-1&-GO:1901838-&&-positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter-%%-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034455-&&-t-UTP complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NOL11				NOL11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOL11	0.39179012	0.19298246	19	4	FALSE	NOL11	NOL11	314	0	19	0	0.74126884	FALSE	0	NOL11	35094	0.10891686
790377	taxon:9606	2.76524342	5.58E-06	173182	1902	zinc finger protein 346	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding	G:9606:ZNF346				ZNF346	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF346	0.36163182	0.16959064	19	4	FALSE	ZNF346	ZNF346	153.5263158	0	19	0	0.70579276	FALSE	0	ZNF346	10840	0.09405877
790378	taxon:9606	2.67843075	1.77E-05	173176	1902	caspase 14	gene	biological_process-&-1&-GO:0008544-&&-epidermis development-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006508-&&-proteolysis-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0097200-&&-cysteine-type endopeptidase activity involved in execution phase of apoptosis-%%-GO:0005515-&&-protein binding	G:9606:CASP14				CASP14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP14	0.37335294	0.0877193	19	4	FALSE	CASP14	CASP14	202.4210526	0	19	0	0.72026154	FALSE	0	CASP14	35230	0.09684009
790417	taxon:9606	2.64109028	2.81E-05	173058	1902	phosphatidylinositol transfer protein beta	gene	biological_process-&-1&-GO:0006997-&&-nucleus organization-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0015914-&&-phospholipid transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008289-&&-lipid binding	G:9606:PITPNB				PITPNB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PITPNB	0.37863151	0.21052632	19	4	FALSE	PITPNB	PITPNB	191.5263158	0	19	0	0.72648495	FALSE	0	PITPNB	32872	0.08096139
790451	taxon:9606	2.75295415	1.60E-05	172813	1902	CDKN1A interacting zinc finger protein 1	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005515-&&-protein binding	G:9606:CIZ1				CIZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CIZ1	0.36324615	0.05847953	19	4	FALSE	CIZ1	CIZ1	192.7368421	0	19	0	0.70784097	FALSE	0	CIZ1	24066	0.11394144
790464	taxon:9606	2.5919332	1.44E-05	172781	1902	ankyrin repeat domain 17	gene	biological_process-&-1&-GO:1900245-&&-positive regulation of MDA-5 signaling pathway-%%-GO:0051151-&&-negative regulation of smooth muscle cell differentiation-%%-GO:0045087-&&-innate immune response-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0016032-&&-viral process-%%-GO:1900246-&&-positive regulation of RIG-I signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016020-&&-membrane-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding	G:9606:ANKRD17				ANKRD17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD17	0.38581241	0.07602339	19	4	FALSE	ANKRD17	ANKRD17	243.4736842	0	19	0	0.7346778	FALSE	0	ANKRD17	33974	0.09180712
790466	taxon:9606	2.6549551	7.93E-06	172782	1902	RAB11 family interacting protein 5	gene	biological_process-&-1&-GO:0035773-&&-insulin secretion involved in cellular response to glucose stimulus-%%-GO:0070164-&&-negative regulation of adiponectin secretion-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0045055-&&-regulated exocytosis-%%-GO:0071468-&&-cellular response to acidic pH|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0055037-&&-recycling endosome-%%-GO:0030141-&&-secretory granule-%%-GO:0005769-&&-early endosome-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0043015-&&-gamma-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:RAB11FIP5			KEGG-&-1&-hsa04144-&&-Endocytosis	RAB11FIP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB11FIP5	0.3766542	0.125	19	4	FALSE	RAB11FIP5	RAB11FIP5	205.3529412	0	18	0	0.72417415	FALSE	1	RAB11FIP5	20086	0.0905197
790472	taxon:9606	2.56908776	1.62E-05	172758	1902	HECT and RLD domain containing E3 ubiquitin protein ligase 4	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HERC4			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	HERC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC4	0.38924322	0.18382353	19	4	FALSE	HERC4	HERC4	258.5882353	0	18	0	0.73848537	FALSE	1	HERC4	26772	0.09266287
790537	taxon:9606	2.65905152	4.42E-05	172550	1902	golgi integral membrane protein 4	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005801-&&-cis-Golgi network-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005796-&&-Golgi lumen	G:9606:GOLIM4				GOLIM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLIM4	0.37607395	0.09356725	19	4	FALSE	GOLIM4	GOLIM4	168.7894737	0	19	0	0.72349141	FALSE	0	GOLIM4	56090	0.07568449
790550	taxon:9606	2.69418623	2.07E-05	172257	1902	heat shock protein family B (small) member 8	gene	biological_process-&-1&-GO:0008150-&&-biological_process-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:HSPB8				HSPB8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB8	0.37116959	0.16911765	19	4	FALSE	HSPB8	HSPB8	160	0	18	0	0.71763563	FALSE	1	HSPB8	28452	0.07919897
790554	taxon:9606	2.72112809	2.94E-05	172234	1902	cyclin and CBS domain divalent metal cation transport mediator 3	gene	biological_process-&-1&-GO:0006811-&&-ion transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CNNM3				CNNM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNNM3	0.36749464	0.05847953	19	4	FALSE	CNNM3	CNNM3	149.8947368	0	19	0	0.71314532	FALSE	0	CNNM3	48494	0.08138402
790624	taxon:9606	2.67228612	2.31E-05	171721	1902	actin like 6B	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0021510-&&-spinal cord development-%%-GO:0006325-&&-chromatin organization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016514-&&-SWI/SNF complex-%%-GO:0071565-&&-nBAF complex-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003713-&&-transcription coactivator activity	G:9606:ACTL6B			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	ACTL6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTL6B	0.37421143	0.10526316	19	4	FALSE	ACTL6B	ACTL6B	182	0	19	0	0.72128565	FALSE	0	ACTL6B	34086	0.08396742
790739	taxon:9606	2.71671656	1.09E-05	171348	1902	tripartite motif containing 17	gene	biological_process-&-1&-GO:0032880-&&-regulation of protein localization-%%-GO:0006914-&&-autophagy-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:TRIM17				TRIM17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM17	0.3680914	0.19883041	19	4	FALSE	TRIM17	TRIM17	167.2631579	0	19	0	0.71388057	FALSE	0	TRIM17	23984	0.08927417
790745	taxon:9606	2.60879156	1.79E-05	171342	1902	potassium channel tetramerization domain containing 3	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization	G:9606:KCTD3				KCTD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCTD3	0.38331924	0.12280702	19	4	FALSE	KCTD3	KCTD3	237.6842105	0	19	0	0.73186807	FALSE	0	KCTD3	31310	0.09363646
790793	taxon:9606	2.77217583	5.06E-05	171184	1902	ceramide synthase 2	gene	biological_process-&-1&-GO:0046513-&&-ceramide biosynthetic process-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:1900148-&&-negative regulation of Schwann cell migration-%%-GO:0048681-&&-negative regulation of axon regeneration-%%-GO:1905045-&&-negative regulation of Schwann cell proliferation involved in axon regeneration|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0050291-&&-sphingosine N-acyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:CERS2			KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	CERS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CERS2	0.36072748	0.07602339	19	4	FALSE	CERS2	CERS2	111.5789474	0	19	0	0.70463736	FALSE	0	CERS2	40968	0.07127685
790808	taxon:9606	2.83929415	1.24E-05	171147	1902	potassium voltage-gated channel interacting protein 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0061337-&&-cardiac conduction-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0072659-&&-protein localization to plasma membrane|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0043679-&&-axon terminus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005267-&&-potassium channel activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:KCNIP3				KCNIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNIP3	0.35220021	0.07352941	19	4	FALSE	KCNIP3	KCNIP3	90.11764706	0	18	0	0.69345097	FALSE	1	KCNIP3	15104	0.07701637
790813	taxon:9606	2.892075	1.16E-05	171134	1902	EH domain containing 2	gene	biological_process-&-1&-GO:2001137-&&-positive regulation of endocytic recycling-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0097320-&&-plasma membrane tubulation-%%-GO:0007596-&&-blood coagulation-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0032456-&&-endocytic recycling-%%-GO:0006897-&&-endocytosis-%%-GO:0030866-&&-cortical actin cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005901-&&-caveola-%%-GO:0010008-&&-endosome membrane-%%-GO:0005829-&&-cytosol-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005525-&&-GTP binding	G:9606:EHD2			KEGG-&-1&-hsa04144-&&-Endocytosis	EHD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EHD2	0.3457725	0.15441176	19	5	FALSE	EHD2	EHD2	101.8823529	0	18	0	0.68465417	FALSE	1	EHD2	13466	0.10882983
790818	taxon:9606	2.7364109	1.89E-05	171116	1902	misshapen like kinase 1	gene	biological_process-&-1&-GO:0048813-&&-dendrite morphogenesis-%%-GO:0030033-&&-microvillus assembly-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007254-&&-JNK cascade-%%-GO:0022407-&&-regulation of cell-cell adhesion-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0007275-&&-multicellular organism development-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MINK1				MINK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MINK1	0.36544219	0.10526316	19	5	FALSE	MINK1	MINK1	140.3157895	0	19	0	0.71059818	FALSE	0	MINK1	26916	0.07911082
790965	taxon:9606	2.66551127	3.67E-05	170569	1902	HEAT repeat containing 3	gene	biological_process-&-1&-GO:0006606-&&-protein import into nucleus-%%-GO:0042273-&&-ribosomal large subunit biogenesis|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding	G:9606:HEATR3				HEATR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEATR3	0.37516255	0.04093567	19	4	FALSE	HEATR3	HEATR3	163.631579	0	19	0	0.72241479	FALSE	0	HEATR3	51936	0.07529206
791030	taxon:9606	2.78115645	1.17E-05	170300	1902	ring finger protein 43	gene	biological_process-&-1&-GO:0072089-&&-stem cell proliferation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0038018-&&-Wnt receptor catabolic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:RNF43			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	RNF43	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF43	0.35956266	0.10294118	19	4	FALSE	RNF43	RNF43	147.3529412	0	18	0	0.70314059	FALSE	1	RNF43	16216	0.09672429
791045	taxon:9606	2.71986765	5.39E-06	170260	1902	ring finger protein 125	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0002250-&&-adaptive immune response-%%-GO:0032480-&&-negative regulation of type I interferon production|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0034098-&&-VCP-NPL4-UFD1 AAA ATPase complex|molecular_function-&-1&-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF125			KEGG-&-1&-hsa04622-&&-RIG-I-like receptor signaling pathway	RNF125	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF125	0.36766495	0.22058824	19	4	FALSE	RNF125	RNF125	186.1764706	0	18	0	0.71335539	FALSE	1	RNF125	13694	0.09988008
791052	taxon:9606	2.78840397	2.90E-05	170213	1902	SPT20 homolog, SAGA complex component	gene	biological_process-&-1&-GO:0007369-&&-gastrulation-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0000124-&&-SAGA complex-%%-GO:0070461-&&-SAGA-type complex-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding	G:9606:SUPT20H			KEGG-&-1&-hsa04140-&&-Autophagy - animal	SUPT20H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT20H	0.35862809	0.25730994	19	5	FALSE	SUPT20H	SUPT20H	113.7368421	0	19	0	0.70193267	FALSE	0	SUPT20H	29062	0.07604295
791189	taxon:9606	2.79029463	1.30E-04	169785	1902	transmembrane protein 30A	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0045332-&&-phospholipid translocation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0070863-&&-positive regulation of protein exit from endoplasmic reticulum-%%-GO:0006855-&&-drug transmembrane transport-%%-GO:0036010-&&-protein localization to endosome|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TMEM30A				TMEM30A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM30A	0.35838509	0.04678363	19	4	FALSE	TMEM30A	TMEM30A	87.57894737	0	19	0	0.70161756	FALSE	0	TMEM30A	84624	0.05942623
791205	taxon:9606	2.73325981	9.34E-05	169729	1902	ring finger protein 130	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0012501-&&-programmed cell death-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RNF130				RNF130	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF130	0.3658635	0.08187135	19	4	FALSE	RNF130	RNF130	154.3684211	0	19	0	0.71112337	FALSE	0	RNF130	89804	0.08673091
791221	taxon:9606	2.80053569	1.32E-05	169695	1902	ELL associated factor 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060770-&&-negative regulation of epithelial cell proliferation involved in prostate gland development-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032783-&&-ELL-EAF complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:EAF2				EAF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EAF2	0.35707454	0.14705882	19	4	FALSE	EAF2	EAF2	113.2941177	0	18	0	0.69991072	FALSE	1	EAF2	19370	0.07966031
791263	taxon:9606	2.76571609	1.21E-05	169450	1902	SR-related CTD associated factor 4	gene	cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:SCAF4				SCAF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAF4	0.36157001	0.08187135	19	4	FALSE	SCAF4	SCAF4	169.0526316	0	19	0	0.70571399	FALSE	0	SCAF4	20872	0.10425539
791380	taxon:9606	2.71277769	8.85E-06	168865	1902	sulfide quinone reductase-like (yeast)	gene	biological_process-&-1&-GO:0070813-&&-hydrogen sulfide metabolic process-%%-GO:0070221-&&-sulfide oxidation, using sulfide:quinone oxidoreductase|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0070224-&&-sulfide:quinone oxidoreductase activity-%%-GO:0048038-&&-quinone binding	G:9606:SQRDL			KEGG-&-1&-hsa00920-&&-Sulfur metabolism	SQRDL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SQRDL	0.36862586	0.09356725	19	4	FALSE	SQRDL	SQRDL	162.5263158	0	19	0	0.71453705	FALSE	0	SQRDL	21368	0.08491008
791428	taxon:9606	2.74586419	1.55E-05	168681	1902	cyclin dependent kinase 15	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDK15				CDK15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDK15	0.36418407	0.12865497	19	4	FALSE	CDK15	CDK15	148.0526316	0	19	0	0.70902264	FALSE	0	CDK15	24106	0.08531728
791443	taxon:9606	2.76224988	1.50E-05	168615	1902	trafficking kinesin protein 2	gene	biological_process-&-1&-GO:0098972-&&-anterograde dendritic transport of mitochondrion-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006605-&&-protein targeting|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0050811-&&-GABA receptor binding	G:9606:TRAK2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04727-&&-GABAergic synapse	TRAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAK2	0.36202373	0.14619883	19	4	FALSE	TRAK2	TRAK2	124	0	19	0	0.70629169	FALSE	0	TRAK2	21758	0.07468037
791481	taxon:9606	2.78021112	1.73E-05	168456	1902	PR/SET domain 14	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007566-&&-embryo implantation-%%-GO:1902459-&&-positive regulation of stem cell population maintenance-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:1902093-&&-positive regulation of flagellated sperm motility-%%-GO:0007281-&&-germ cell development-%%-GO:0009566-&&-fertilization-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0001708-&&-cell fate specification-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034972-&&-histone H3-R26 methylation-%%-GO:0001827-&&-inner cell mass cell fate commitment-%%-GO:0030718-&&-germ-line stem cell population maintenance-%%-GO:0044030-&&-regulation of DNA methylation-%%-GO:0060817-&&-inactivation of paternal X chromosome-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0000902-&&-cell morphogenesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031490-&&-chromatin DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008168-&&-methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:PRDM14				PRDM14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRDM14	0.35968491	0.05847953	19	4	FALSE	PRDM14	PRDM14	120.5789474	0	19	0	0.70329815	FALSE	0	PRDM14	25768	0.07863737
791516	taxon:9606	2.67244367	4.54E-06	168313	1902	mitochondrial ribosomal protein S25	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:MRPS25				MRPS25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPS25	0.37418936	0.38596491	19	4	FALSE	MRPS25	MRPS25	217.2631579	0	19	0	0.72125939	FALSE	0	MRPS25	14956	0.10072469
791531	taxon:9606	2.65227667	3.89E-05	168231	1902	protein disulfide isomerase family A member 2	gene	biological_process-&-1&-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0006457-&&-protein folding-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0019511-&&-peptidyl-proline hydroxylation-%%-GO:0006621-&&-protein retention in ER lumen-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:1902175-&&-regulation of oxidative stress-induced intrinsic apoptotic signaling pathway-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0015036-&&-disulfide oxidoreductase activity-%%-GO:0005496-&&-steroid binding-%%-GO:0005515-&&-protein binding-%%-GO:0031545-&&-peptidyl-proline 4-dioxygenase activity	G:9606:PDIA2				PDIA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIA2	0.37703457	0.22222222	19	4	FALSE	PDIA2	PDIA2	210.7894737	0	19	0	0.72462056	FALSE	0	PDIA2	43916	0.09409746
791534	taxon:9606	2.62754057	5.99E-05	168216	1902	SET and MYND domain containing 3	gene	biological_process-&-1&-GO:0014904-&&-myotube cell development-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0034968-&&-histone lysine methylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0018024-&&-histone-lysine N-methyltransferase activity-%%-GO:0000993-&&-RNA polymerase II core binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001162-&&-RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:SMYD3				SMYD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMYD3	0.38058404	0.06432749	19	5	FALSE	SMYD3	SMYD3	182.8947368	0	19	0	0.72874324	FALSE	0	SMYD3	57370	0.07544295
791618	taxon:9606	2.68993225	2.72E-05	167791	1902	calmodulin-lysine N-methyltransferase	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0018022-&&-peptidyl-lysine methylation-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0018025-&&-calmodulin-lysine N-methyltransferase activity	G:9606:CAMKMT			KEGG-&-1&-hsa00310-&&-Lysine degradation	CAMKMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMKMT	0.37175657	0.10526316	19	4	FALSE	CAMKMT	CAMKMT	169.4210526	0	19	0	0.71834462	FALSE	0	CAMKMT	37284	0.08358061
791637	taxon:9606	2.72569718	2.09E-05	167711	1902	transcription elongation factor A like 4	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:TCEAL4				TCEAL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEAL4	0.36687861	0.11695906	19	4	FALSE	TCEAL4	TCEAL4	136.3157895	0	19	0	0.7123838	FALSE	0	TCEAL4	24826	0.0743457
791697	taxon:9606	2.75011817	1.08E-05	167383	1902	ILK associated serine/threonine phosphatase	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:ILKAP				ILKAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ILKAP	0.36362074	0.13450292	19	5	FALSE	ILKAP	ILKAP	134.3684211	0	19	0	0.70831364	FALSE	0	ILKAP	17996	0.0802065
791756	taxon:9606	2.71514101	1.04E-05	167023	1902	mitochondrial ribosomal protein L43	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070126-&&-mitochondrial translational termination|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005761-&&-mitochondrial ribosome-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:MRPL43				MRPL43	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRPL43	0.368305	0.28070175	19	4	FALSE	MRPL43	MRPL43	226.6842105	0	19	0	0.71414316	FALSE	0	MRPL43	20800	0.11922438
791821	taxon:9606	2.76508587	2.96E-05	166692	1902	cAMP responsive element binding protein 3 like 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CREB3L3			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB3L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB3L3	0.36165242	0.125	19	5	FALSE	CREB3L3	CREB3L3	133	0	18	0	0.70581902	FALSE	1	CREB3L3	39100	0.08292611
791850	taxon:9606	2.59240586	1.76E-05	166592	1902	F-box protein, helicase, 18	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0008219-&&-cell death-%%-GO:2000042-&&-negative regulation of double-strand break repair via homologous recombination-%%-GO:0031297-&&-replication fork processing-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0072429-&&-response to intra-S DNA damage checkpoint signaling-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0000737-&&-DNA catabolic process, endonucleolytic-%%-GO:0048478-&&-replication fork protection-%%-GO:1902231-&&-positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0043138-&&-3'-5' DNA helicase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0015616-&&-DNA translocase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0004003-&&-ATP-dependent DNA helicase activity	G:9606:FBXO18				FBXO18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO18	0.38574207	0.26900585	19	4	FALSE	FBXO18	FBXO18	271.5789474	0	19	0	0.73459902	FALSE	0	FBXO18	29398	0.10261666
791859	taxon:9606	2.95068536	1.25E-05	182970	1902	acetyl-CoA acyltransferase 1	gene	biological_process-&-1&-GO:0008206-&&-bile acid metabolic process-%%-GO:0033540-&&-fatty acid beta-oxidation using acyl-CoA oxidase-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0000038-&&-very long-chain fatty acid metabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0035580-&&-specific granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003988-&&-acetyl-CoA C-acyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008775-&&-acetate CoA-transferase activity-%%-GO:0016401-&&-palmitoyl-CoA oxidase activity	G:9606:ACAA1			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa00071-&&-Fatty acid degradation	ACAA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAA1	0.33890431	0.11695906	19	4	FALSE	ACAA1	ACAA1	49.05263158	0	19	0	0.67488577	FALSE	0	ACAA1	10842	0.07521118
791885	taxon:9606	2.84638412	1.34E-05	182926	1902	adrenoceptor alpha 2A	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:0071881-&&-adenylate cyclase-inhibiting adrenergic receptor signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0030168-&&-platelet activation-%%-GO:0032811-&&-negative regulation of epinephrine secretion-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0071883-&&-activation of MAPK activity by adrenergic receptor signaling pathway-%%-GO:0071882-&&-phospholipase C-activating adrenergic receptor signaling pathway-%%-GO:0035625-&&-epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0010700-&&-negative regulation of norepinephrine secretion-%%-GO:0042593-&&-glucose homeostasis-%%-GO:1901020-&&-negative regulation of calcium ion transmembrane transporter activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0050892-&&-intestinal absorption-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0045955-&&-negative regulation of calcium ion-dependent exocytosis-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0071878-&&-negative regulation of adrenergic receptor signaling pathway-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007165-&&-signal transduction-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0061179-&&-negative regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0043406-&&-positive regulation of MAP kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043235-&&-receptor complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004938-&&-alpha2-adrenergic receptor activity-%%-GO:0031696-&&-alpha-2C adrenergic receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051379-&&-epinephrine binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0032795-&&-heterotrimeric G-protein binding-%%-GO:0031996-&&-thioesterase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031692-&&-alpha-1B adrenergic receptor binding-%%-GO:0051380-&&-norepinephrine binding	G:9606:ADRA2A	ADRA2A	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRA2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRA2A	0.35132293	0.13970588	19	4	FALSE	ADRA2A	ADRA2A	89.94117647	0	18	0	0.69226931	FALSE	1	ADRA2A	16540	0.07915759
791910	taxon:9606	2.75531747	9.31E-06	182890	1902	nuclear receptor subfamily 0 group B member 1	gene	biological_process-&-1&-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006694-&&-steroid biosynthetic process-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0021983-&&-pituitary gland development-%%-GO:0033144-&&-negative regulation of intracellular steroid hormone receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030325-&&-adrenal gland development-%%-GO:0060008-&&-Sertoli cell differentiation-%%-GO:0021854-&&-hypothalamus development-%%-GO:0030238-&&-male sex determination-%%-GO:0008406-&&-gonad development-%%-GO:0008104-&&-protein localization-%%-GO:0008584-&&-male gonad development-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0035902-&&-response to immobilization stress|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0042788-&&-polysomal ribosome-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0032448-&&-DNA hairpin binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0003723-&&-RNA binding-%%-GO:0035258-&&-steroid hormone receptor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:NR0B1			KEGG-&-1&-hsa04927-&&-Cortisol synthesis and secretion	NR0B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR0B1	0.36293458	0.16959064	19	5	FALSE	NR0B1	NR0B1	164.7894737	0	19	0	0.70744709	FALSE	0	NR0B1	20464	0.09802632
791956	taxon:9606	2.6385694	2.73E-05	182810	1902	ankyrin 3	gene	biological_process-&-1&-GO:0071709-&&-membrane assembly-%%-GO:0071286-&&-cellular response to magnesium ion-%%-GO:0007165-&&-signal transduction-%%-GO:2001259-&&-positive regulation of cation channel activity-%%-GO:0072660-&&-maintenance of protein location in plasma membrane-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0043001-&&-Golgi to plasma membrane protein transport-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0010960-&&-magnesium ion homeostasis-%%-GO:0019228-&&-neuronal action potential-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0045838-&&-positive regulation of membrane potential-%%-GO:2000651-&&-positive regulation of sodium ion transmembrane transporter activity-%%-GO:0010650-&&-positive regulation of cell communication by electrical coupling-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0034112-&&-positive regulation of homotypic cell-cell adhesion-%%-GO:0007409-&&-axonogenesis-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:0043266-&&-regulation of potassium ion transport-%%-GO:1900827-&&-positive regulation of membrane depolarization during cardiac muscle cell action potential|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0043034-&&-costamere-%%-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0043194-&&-axon initial segment-%%-GO:0005829-&&-cytosol-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0033268-&&-node of Ranvier-%%-GO:0042383-&&-sarcolemma-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005764-&&-lysosome-%%-GO:0009986-&&-cell surface-%%-GO:0030018-&&-Z disc-%%-GO:0030315-&&-T-tubule-%%-GO:0043005-&&-neuron projection-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0014704-&&-intercalated disc-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0045296-&&-cadherin binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0008092-&&-cytoskeletal protein binding	G:9606:ANK3			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	ANK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANK3	0.37899325	0.04093567	19	4	FALSE	ANK3	ANK3	186.0526316	0	19	0	0.7269051	FALSE	0	ANK3	37134	0.07905945
791968	taxon:9606	2.79470616	1.68E-05	182789	1902	apoptotic peptidase activating factor 1	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:1902510-&&-regulation of apoptotic DNA fragmentation-%%-GO:0007399-&&-nervous system development-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0001666-&&-response to hypoxia-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007568-&&-aging-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001843-&&-neural tube closure-%%-GO:0030900-&&-forebrain development-%%-GO:0007584-&&-response to nutrient-%%-GO:0008635-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c-%%-GO:0030154-&&-cell differentiation-%%-GO:0072432-&&-response to G1 DNA damage checkpoint signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0010659-&&-cardiac muscle cell apoptotic process-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0034349-&&-glial cell apoptotic process|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0043293-&&-apoptosome-%%-GO:1904813-&&-ficolin-1-rich granule lumen|molecular_function-&-1&-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0043531-&&-ADP binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0005524-&&-ATP binding	G:9606:APAF1			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa05010-&&-Alzheimer disease-%%-hsa05012-&&-Parkinson disease-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04210-&&-Apoptosis-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05016-&&-Huntington disease-%%-hsa01524-&&-Platinum drug resistance	APAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APAF1	0.35781937	0.16959064	19	4	FALSE	APAF1	APAF1	107.2105263	0	19	0	0.70088231	FALSE	0	APAF1	21744	0.07821744
791998	taxon:9606	2.76020167	4.29E-05	182754	1902	BCL2 like 2	gene	biological_process-&-1&-GO:0060011-&&-Sertoli cell proliferation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031966-&&-mitochondrial membrane|molecular_function-&-1&-GO:0051400-&&-BH domain binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:BCL2L2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	BCL2L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L2	0.36229237	0.12280702	19	4	FALSE	BCL2L2	BCL2L2	117.5789474	0	19	0	0.70663305	FALSE	0	BCL2L2	47882	0.07134858
792140	taxon:9606	2.77501182	1.72E-05	166146	1902	kinetochore localized astrin/SPAG5 binding protein	gene	biological_process-&-1&-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0051988-&&-regulation of attachment of spindle microtubules to kinetochore-%%-GO:0051301-&&-cell division-%%-GO:0007059-&&-chromosome segregation-%%-GO:0007051-&&-spindle organization|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0035371-&&-microtubule plus-end-%%-GO:0072686-&&-mitotic spindle-%%-GO:0000776-&&-kinetochore-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KNSTRN				KNSTRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KNSTRN	0.36035883	0.14619883	19	4	FALSE	KNSTRN	KNSTRN	136.8947368	0	19	0	0.7041647	FALSE	0	KNSTRN	22442	0.08992382
792196	taxon:9606	2.69292579	2.96E-05	182450	1902	ADP ribosylation factor like GTPase 3	gene	biological_process-&-1&-GO:0042461-&&-photoreceptor cell development-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0042073-&&-intraciliary transport-%%-GO:0000910-&&-cytokinesis-%%-GO:0001822-&&-kidney development-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0005876-&&-spindle microtubule|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding-%%-GO:0046872-&&-metal ion binding	G:9606:ARL3				ARL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARL3	0.37134332	0.11695906	19	4	FALSE	ARL3	ARL3	203.2105263	0	19	0	0.7178457	FALSE	0	ARL3	36536	0.10023947
792213	taxon:9606	2.81329762	1.51E-05	166019	1902	UBX domain protein 11	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBXN11				UBXN11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN11	0.35545475	0.07602339	19	4	FALSE	UBXN11	UBXN11	92.05263158	0	19	0	0.69778373	FALSE	0	UBXN11	19408	0.07259241
792219	taxon:9606	2.74413109	9.35E-06	166008	1902	nexilin F-actin binding protein	gene	biological_process-&-1&-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0048739-&&-cardiac muscle fiber development|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0008307-&&-structural constituent of muscle-%%-GO:0051015-&&-actin filament binding	G:9606:NEXN				NEXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEXN	0.36441408	0.42690058	19	5	FALSE	NEXN	NEXN	184.1052632	0	19	0	0.70931149	FALSE	0	NEXN	17686	0.10589946
792327	taxon:9606	2.83645817	1.10E-05	165838	1902	egl-9 family hypoxia inducible factor 2	gene	biological_process-&-1&-GO:0001558-&&-regulation of cell growth-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0018401-&&-peptidyl-proline hydroxylation to 4-hydroxy-L-proline-%%-GO:0045732-&&-positive regulation of protein catabolic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019826-&&-oxygen sensor activity-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0005515-&&-protein binding-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0031545-&&-peptidyl-proline 4-dioxygenase activity-%%-GO:0031418-&&-L-ascorbic acid binding	G:9606:EGLN2			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04066-&&-HIF-1 signaling pathway	EGLN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EGLN2	0.35255235	0.20588235	19	5	FALSE	EGLN2	EGLN2	92.23529412	0	18	0	0.69392364	FALSE	1	EGLN2	16364	0.07724899
792351	taxon:9606	2.68426028	3.21E-05	165794	1902	cytokine dependent hematopoietic cell linker	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0009967-&&-positive regulation of signal transduction|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:CLNK				CLNK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLNK	0.37254211	0.1754386	19	4	FALSE	CLNK	CLNK	169.1052632	0	19	0	0.71928995	FALSE	0	CLNK	41840	0.08195087
792364	taxon:9606	2.67984875	9.21E-06	182158	1902	adaptor related protein complex 1 sigma 1 subunit	gene	biological_process-&-1&-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0009615-&&-response to virus-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0030121-&&-AP-1 adaptor complex-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0043195-&&-terminal bouton-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008565-&&-protein transporter activity	G:9606:AP1S1			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1S1	0.37315539	0.35294118	19	4	FALSE	AP1S1	AP1S1	167.9411765	0	18	0	0.72002521	FALSE	1	AP1S1	15924	0.07984993
792391	taxon:9606	2.6831574	2.58E-05	182100	1902	cysteine rich protein 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030097-&&-hemopoiesis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:CRIP2				CRIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRIP2	0.37269524	0.02923977	19	4	FALSE	CRIP2	CRIP2	153.7368421	0	19	0	0.71947377	FALSE	0	CRIP2	37994	0.07463835
792474	taxon:9606	2.76886718	1.72E-05	181967	1902	bile acid-CoA:amino acid N-acyltransferase	gene	biological_process-&-1&-GO:0006637-&&-acyl-CoA metabolic process-%%-GO:0006544-&&-glycine metabolic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0019530-&&-taurine metabolic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0002152-&&-bile acid conjugation-%%-GO:0008206-&&-bile acid metabolic process-%%-GO:0001889-&&-liver development|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0047963-&&-glycine N-choloyltransferase activity-%%-GO:0052815-&&-medium-chain acyl-CoA hydrolase activity-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0052817-&&-very long chain acyl-CoA hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016746-&&-transferase activity, transferring acyl groups-%%-GO:0052816-&&-long-chain acyl-CoA hydrolase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0102991-&&-myristoyl-CoA hydrolase activity-%%-GO:0016410-&&-N-acyltransferase activity-%%-GO:0016290-&&-palmitoyl-CoA hydrolase activity	G:9606:BAAT			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00430-&&-Taurine and hypotaurine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis-%%-hsa04976-&&-Bile secretion-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids	BAAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BAAT	0.36115853	0.04093567	19	4	FALSE	BAAT	BAAT	126.3157895	0	19	0	0.7051888	FALSE	0	BAAT	29216	0.08029001
792487	taxon:9606	2.74917284	3.06E-05	181941	1902	complement C1q A chain	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0045087-&&-innate immune response-%%-GO:0010039-&&-response to iron ion-%%-GO:0006956-&&-complement activation-%%-GO:0006508-&&-proteolysis-%%-GO:0006958-&&-complement activation, classical pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005602-&&-complement component C1 complex-%%-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:C1QA			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05020-&&-Prion diseases-%%-hsa05133-&&-Pertussis-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	C1QA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QA	0.36374577	0.09356725	19	4	FALSE	C1QA	C1QA	117.8947368	0	19	0	0.70847119	FALSE	0	C1QA	32330	0.07175866
792503	taxon:9606	2.91334489	3.98E-05	181896	1902	carbonic anhydrase 8	gene	biological_process-&-1&-GO:0006730-&&-one-carbon metabolic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004089-&&-carbonate dehydratase activity-%%-GO:0005515-&&-protein binding	G:9606:CA8			KEGG-&-1&-hsa00910-&&-Nitrogen metabolism	CA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CA8	0.34324807	0.01169591	19	4	FALSE	CA8	CA8	46.31578947	0	19	0	0.68110919	FALSE	0	CA8	26152	0.06063158
792765	taxon:9606	2.7496455	1.15E-05	165030	1902	ankyrin repeat and SOCS box containing 17	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005622-&&-intracellular	G:9606:ASB17				ASB17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASB17	0.36368325	0.11695906	19	4	FALSE	ASB17	ASB17	146.0526316	0	19	0	0.70839242	FALSE	0	ASB17	23744	0.08704937
792852	taxon:9606	2.62423192	2.93E-05	181270	1902	ERCC excision repair 1, endonuclease non-catalytic subunit	gene	biological_process-&-1&-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:1905765-&&-negative regulation of protection from non-homologous end joining at telomere-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006312-&&-mitotic recombination-%%-GO:0061819-&&-telomeric DNA-containing double minutes formation-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0000710-&&-meiotic mismatch repair-%%-GO:0006281-&&-DNA repair-%%-GO:0048477-&&-oogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0070914-&&-UV-damage excision repair-%%-GO:0007584-&&-response to nutrient-%%-GO:0001302-&&-replicative cell aging-%%-GO:0006310-&&-DNA recombination-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:1904431-&&-positive regulation of t-circle formation-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0010165-&&-response to X-ray-%%-GO:0090656-&&-t-circle formation-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0045190-&&-isotype switching-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0032205-&&-negative regulation of telomere maintenance-%%-GO:0048568-&&-embryonic organ development-%%-GO:0009744-&&-response to sucrose-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0006949-&&-syncytium formation-%%-GO:0008584-&&-male gonad development-%%-GO:0009650-&&-UV protection-%%-GO:0035166-&&-post-embryonic hemopoiesis-%%-GO:0000720-&&-pyrimidine dimer repair by nucleotide-excision repair|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000109-&&-nucleotide-excision repair complex-%%-GO:0000110-&&-nucleotide-excision repair factor 1 complex-%%-GO:0070522-&&-ERCC4-ERCC1 complex-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0000014-&&-single-stranded DNA endodeoxyribonuclease activity-%%-GO:1990599-&&-3' overhang single-stranded DNA endodeoxyribonuclease activity-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0003697-&&-single-stranded DNA binding	G:9606:ERCC1			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway-%%-hsa03420-&&-Nucleotide excision repair-%%-hsa01524-&&-Platinum drug resistance	ERCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC1	0.38106388	0.11695906	19	5	FALSE	ERCC1	ERCC1	182.2105263	0	19	0	0.72929468	FALSE	0	ERCC1	42236	0.07417341
792871	taxon:9606	2.52355444	3.01E-05	181244	1902	electron transfer flavoprotein beta subunit	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0005515-&&-protein binding	G:9606:ETFB				ETFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETFB	0.39626647	0.16374269	19	4	FALSE	ETFB	ETFB	279.2105263	0	19	0	0.74607426	FALSE	0	ETFB	53696	0.09124069
792887	taxon:9606	2.82180558	4.18E-05	181212	1902	F2R like trypsin receptor 1	gene	biological_process-&-1&-GO:0035926-&&-chemokine (C-C motif) ligand 2 secretion-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0042119-&&-neutrophil activation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050900-&&-leukocyte migration-%%-GO:0072608-&&-interleukin-10 secretion-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0007596-&&-blood coagulation-%%-GO:0034137-&&-positive regulation of toll-like receptor 2 signaling pathway-%%-GO:0090198-&&-negative regulation of chemokine secretion-%%-GO:0002741-&&-positive regulation of cytokine secretion involved in immune response-%%-GO:0070963-&&-positive regulation of neutrophil mediated killing of gram-negative bacterium-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0043311-&&-positive regulation of eosinophil degranulation-%%-GO:2000484-&&-positive regulation of interleukin-8 secretion-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0030836-&&-positive regulation of actin filament depolymerization-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0090195-&&-chemokine secretion-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0034141-&&-positive regulation of toll-like receptor 3 signaling pathway-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:1900135-&&-positive regulation of renin secretion into blood stream-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0050702-&&-interleukin-1 beta secretion-%%-GO:0097029-&&-mature conventional dendritic cell differentiation-%%-GO:0003104-&&-positive regulation of glomerular filtration-%%-GO:0070493-&&-thrombin-activated receptor signaling pathway-%%-GO:0072643-&&-interferon-gamma secretion-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0034140-&&-negative regulation of toll-like receptor 3 signaling pathway-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0070661-&&-leukocyte proliferation-%%-GO:0045087-&&-innate immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0031143-&&-pseudopodium-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0004872-&&-receptor activity-%%-GO:0015057-&&-thrombin-activated receptor activity-%%-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005102-&&-receptor binding	G:9606:F2RL1			KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	F2RL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F2RL1	0.35438303	0.02339181	19	4	FALSE	F2RL1	F2RL1	79.05263158	0	19	0	0.69636574	FALSE	0	F2RL1	36104	0.06343871
792894	taxon:9606	3.03923113	2.56E-05	181204	1902	coagulation factor X	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006465-&&-signal peptide processing-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0007598-&&-blood coagulation, extrinsic pathway-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007597-&&-blood coagulation, intrinsic pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031233-&&-intrinsic component of external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:F10	F10	TRUE	KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F10	0.32903059	0.07352941	19	5	FALSE	F10	F10	27.94117647	0	18	0	0.66012814	FALSE	1	F10	17892	0.07052821
793028	taxon:9606	2.68110919	7.88E-06	180874	1902	Rap guanine nucleotide exchange factor 1	gene	biological_process-&-1&-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0001568-&&-blood vessel development-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:2000178-&&-negative regulation of neural precursor cell proliferation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:1905451-&&-positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0007165-&&-signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1901888-&&-regulation of cell junction assembly-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0061028-&&-establishment of endothelial barrier|cellular_component-&-1&-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017034-&&-Rap guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:RAPGEF1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05211-&&-Renal cell carcinoma	RAPGEF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAPGEF1	0.37297996	0.43859649	19	4	FALSE	RAPGEF1	RAPGEF1	219.1052632	0	19	0	0.71981514	FALSE	0	RAPGEF1	17520	0.10508637
793031	taxon:9606	2.85961872	8.57E-06	180865	1902	glutamate ionotropic receptor kainate type subunit 2	gene	biological_process-&-1&-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:0006810-&&-transport-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0051967-&&-negative regulation of synaptic transmission, glutamatergic-%%-GO:0043113-&&-receptor clustering-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0048172-&&-regulation of short-term neuronal synaptic plasticity-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043195-&&-terminal bouton-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0015277-&&-kainate selective glutamate receptor activity	G:9606:GRIK2			KEGG-&-1&-hsa04724-&&-Glutamatergic synapse-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRIK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIK2	0.34969697	0.19117647	19	4	FALSE	GRIK2	GRIK2	90.58823529	0	18	0	0.69006355	FALSE	1	GRIK2	11730	0.08211786
793057	taxon:9606	2.76224988	2.01E-04	180822	1902	glutathione S-transferase mu 3	gene	biological_process-&-1&-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0043627-&&-response to estrogen-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0008065-&&-establishment of blood-nerve barrier-%%-GO:0018916-&&-nitrobenzene metabolic process-%%-GO:0070458-&&-cellular detoxification of nitrogen compound-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0035686-&&-sperm fibrous sheath-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0043295-&&-glutathione binding-%%-GO:0042802-&&-identical protein binding	G:9606:GSTM3			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTM3	0.36202373	0.05147059	19	4	FALSE	GSTM3	GSTM3	133.7647059	0	18	0	0.70629169	FALSE	1	GSTM3	232022	0.08161135
793093	taxon:9606	2.70442729	3.22E-06	164357	1902	chromosome 11 open reading frame 84	gene		G:9606:C11orf84				C11orf84	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C11orf84	0.36976405	0.46783626	19	4	FALSE	C11orf84	C11orf84	319.3684211	0	19	0	0.71592879	FALSE	0	C11orf84	14408	0.16162558
793159	taxon:9606	2.73231448	1.21E-04	180619	1902	G protein subunit alpha 15	gene	biological_process-&-1&-GO:0007207-&&-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0030168-&&-platelet activation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004871-&&-signal transducer activity	G:9606:GNA15			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04926-&&-Relaxin signaling pathway	GNA15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNA15	0.36599008	0.0877193	19	5	FALSE	GNA15	GNA15	118.8421053	0	19	0	0.71128092	FALSE	0	GNA15	97852	0.06672985
793188	taxon:9606	2.69670711	4.40E-05	180562	1902	hippocalcin like 1	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:HPCAL1				HPCAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPCAL1	0.37082262	0.16959064	19	4	FALSE	HPCAL1	HPCAL1	162.7368421	0	19	0	0.71721548	FALSE	0	HPCAL1	69828	0.08070001
793330	taxon:9606	2.81597605	9.56E-06	180308	1902	zinc finger and BTB domain containing 48	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010833-&&-telomere maintenance via telomere lengthening-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003691-&&-double-stranded telomeric DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ZBTB48				ZBTB48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB48	0.35511666	0.03676471	19	5	FALSE	ZBTB48	ZBTB48	99.41176471	0	18	0	0.69733732	FALSE	1	ZBTB48	13894	0.07662118
787063	taxon:9606	2.83283441	1.15E-04	180133	1902	interferon alpha and beta receptor subunit 2	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0035455-&&-response to interferon-alpha-%%-GO:0035456-&&-response to interferon-beta-%%-GO:0008283-&&-cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004905-&&-type I interferon receptor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:IFNAR2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis	IFNAR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNAR2	0.35300334	0.30833333	18	5	FALSE	IFNAR2	IFNAR2	117.625	0	17	0	0.6945276	FALSE	1	IFNAR2	222104	0.09940778
787165	taxon:9606	2.7795809	4.04E-05	179941	1902	latent transforming growth factor beta binding protein 1	gene	biological_process-&-1&-GO:0003281-&&-ventricular septum development-%%-GO:0035583-&&-sequestering of TGFbeta in extracellular matrix-%%-GO:0035904-&&-aorta development-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0060976-&&-coronary vasculature development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0001527-&&-microfibril-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0043234-&&-protein complex-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0050436-&&-microfibril binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0005515-&&-protein binding	G:9606:LTBP1	LTBP1	TRUE	KEGG-&-1&-hsa04350-&&-TGF-beta signaling pathway	LTBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTBP1	0.35976647	0.075	18	5	FALSE	LTBP1	LTBP1	131.8125	0	17	0	0.70340318	FALSE	1	LTBP1	41172	0.08564211
787212	taxon:9606	2.52103356	1.17E-05	179859	1902	megakaryocyte-associated tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0008283-&&-cell proliferation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007498-&&-mesoderm development-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:MATK			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	MATK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MATK	0.39666271	0.26143791	18	4	FALSE	MATK	MATK	297.6666667	0	18	0	0.74649441	FALSE	0	MATK	27312	0.09662698
787231	taxon:9606	2.85820072	1.18E-05	179827	1902	insulin induced gene 1	gene	biological_process-&-1&-GO:0032933-&&-SREBP signaling pathway-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0060021-&&-palate development-%%-GO:0008152-&&-metabolic process-%%-GO:1901303-&&-negative regulation of cargo loading into COPII-coated vesicle-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0010894-&&-negative regulation of steroid biosynthetic process-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0060363-&&-cranial suture morphogenesis|cellular_component-&-1&-GO:0032937-&&-SREBP-SCAP-Insig complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:INSIG1				INSIG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSIG1	0.34987046	0.33333333	18	4	FALSE	INSIG1	INSIG1	99.3125	0	17	0	0.69029988	FALSE	1	INSIG1	14652	0.09360273
787349	taxon:9606	2.80652277	9.84E-05	179614	1902	lipopolysaccharide binding protein	gene	biological_process-&-1&-GO:0015920-&&-lipopolysaccharide transport-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0008228-&&-opsonization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0071223-&&-cellular response to lipoteichoic acid-%%-GO:0002281-&&-macrophage activation involved in immune response-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0006968-&&-cellular defense response-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0060265-&&-positive regulation of respiratory burst involved in inflammatory response-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:0032490-&&-detection of molecule of bacterial origin-%%-GO:0006953-&&-acute-phase response-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0002232-&&-leukocyte chemotaxis involved in inflammatory response-%%-GO:0032722-&&-positive regulation of chemokine production|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0070891-&&-lipoteichoic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding	G:9606:LBP	LBP	TRUE	KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04064-&&-NF-kappa B signaling pathway	LBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LBP	0.35631281	0.03267974	18	5	FALSE	LBP	LBP	93	0	18	0	0.69891287	FALSE	0	LBP	83630	0.06883428
787367	taxon:9606	2.674807	2.32E-05	179553	1902	MAX interactor 1, dimerization protein	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0042994-&&-cytoplasmic sequestering of transcription factor-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:MXI1				MXI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MXI1	0.37385875	0.23529412	18	4	FALSE	MXI1	MXI1	183.0555556	0	18	0	0.7208655	FALSE	0	MXI1	56604	0.08579466
787443	taxon:9606	2.84276036	8.16E-05	179426	1902	DnaJ heat shock protein family (Hsp40) member B9	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005730-&&-nucleolus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051787-&&-misfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJB9				DNAJB9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB9	0.35177077	0.01960784	18	4	FALSE	DNAJB9	DNAJB9	75.77777778	0	18	0	0.69287327	FALSE	0	DNAJB9	81688	0.06781193
787545	taxon:9606	2.68299984	8.49E-06	179213	1902	protein phosphatase 2 regulatory subunit B''alpha	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0061053-&&-somite development-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0000159-&&-protein phosphatase type 2A complex|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:PPP2R3A			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R3A	0.37271713	0.21666667	18	4	FALSE	PPP2R3A	PPP2R3A	212.5625	0	17	0	0.71950003	FALSE	1	PPP2R3A	19232	0.10128694
787598	taxon:9606	2.70679061	1.99E-05	179122	1902	nuclear factor of activated T-cells 4	gene	biological_process-&-1&-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:2000297-&&-negative regulation of synapse maturation-%%-GO:0007507-&&-heart development-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0055001-&&-muscle cell development-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0035562-&&-negative regulation of chromatin binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0034644-&&-cellular response to UV-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0006954-&&-inflammatory response-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045333-&&-cellular respiration|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0042975-&&-peroxisome proliferator activated receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFATC4			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	NFATC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC4	0.36944121	0.09803922	18	4	FALSE	NFATC4	NFATC4	175.2222222	0	18	0	0.7155349	FALSE	0	NFATC4	27872	0.09035314
787615	taxon:9606	2.8126674	2.69E-05	179095	1902	nidogen 1	gene	biological_process-&-1&-GO:0071711-&&-basement membrane organization-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0032836-&&-glomerular basement membrane development|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005604-&&-basement membrane-%%-GO:0005605-&&-basal lamina-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0043237-&&-laminin-1 binding-%%-GO:0043236-&&-laminin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0043394-&&-proteoglycan binding	G:9606:NID1				NID1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NID1	0.35553439	0.1	18	4	FALSE	NID1	NID1	98.5	0	17	0	0.69788877	FALSE	1	NID1	23570	0.07249447
787637	taxon:9606	2.96565306	1.63E-05	162662	1902	HEPACAM family member 2	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0051297-&&-centrosome organization|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005819-&&-spindle-%%-GO:0005813-&&-centrosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:HEPACAM2				HEPACAM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HEPACAM2	0.33719386	0.03921569	18	4	FALSE	HEPACAM2	HEPACAM2	40.61111111	0	18	0	0.67239116	FALSE	0	HEPACAM2	16884	0.07191303
787685	taxon:9606	2.69276824	5.27E-05	178955	1902	phosphatidylinositol transfer protein alpha	gene	biological_process-&-1&-GO:0006629-&&-lipid metabolic process-%%-GO:0007601-&&-visual perception-%%-GO:0015914-&&-phospholipid transport-%%-GO:0006810-&&-transport-%%-GO:0007409-&&-axonogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0008525-&&-phosphatidylcholine transporter activity-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:1901611-&&-phosphatidylglycerol binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0008526-&&-phosphatidylinositol transporter activity	G:9606:PITPNA				PITPNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PITPNA	0.37136505	0.04575163	18	4	FALSE	PITPNA	PITPNA	141.4444444	0	18	0	0.71787196	FALSE	0	PITPNA	42626	0.07017107
787703	taxon:9606	2.87301087	3.93E-05	178918	1902	serpin family F member 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0006953-&&-acute-phase response-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0010033-&&-response to organic substance-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0042730-&&-fibrinolysis-%%-GO:0010757-&&-negative regulation of plasminogen activation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0071636-&&-positive regulation of transforming growth factor beta production-%%-GO:0002034-&&-regulation of blood vessel diameter by renin-angiotensin-%%-GO:0051496-&&-positive regulation of stress fiber assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005577-&&-fibrinogen complex|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:SERPINF2	SERPINF2	TRUE	KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	SERPINF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINF2	0.3480669	0.06666667	18	5	FALSE	SERPINF2	SERPINF2	78.9375	0	17	0	0.68783152	FALSE	1	SERPINF2	33738	0.0773399
787779	taxon:9606	2.76161966	2.51E-05	178796	1902	protein phosphatase 3 regulatory subunit B, alpha	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0022011-&&-myelination in peripheral nervous system-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0051531-&&-NFAT protein import into nucleus-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005955-&&-calcineurin complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005654-&&-nucleoplasm-%%-GO:0042383-&&-sarcolemma-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004723-&&-calcium-dependent protein serine/threonine phosphatase activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding	G:9606:PPP3R1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3R1	0.36210634	0.1372549	18	4	FALSE	PPP3R1	PPP3R1	122.7222222	0	18	0	0.70639672	FALSE	0	PPP3R1	28568	0.07559255
787795	taxon:9606	2.63431542	1.88E-05	178775	1902	primase (DNA) subunit 1	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006269-&&-DNA replication, synthesis of RNA primer-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005658-&&-alpha DNA polymerase:primase complex|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003896-&&-DNA primase activity	G:9606:PRIM1			KEGG-&-1&-hsa03030-&&-DNA replication	PRIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRIM1	0.37960526	0.2875817	18	4	FALSE	PRIM1	PRIM1	226	0	18	0	0.7276141	FALSE	0	PRIM1	30014	0.09418276
787812	taxon:9606	2.7082086	1.20E-05	178753	1902	protein kinase C eta	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0070528-&&-protein kinase C signaling-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:1903078-&&-positive regulation of protein localization to plasma membrane-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0034351-&&-negative regulation of glial cell apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017160-&&-Ral GTPase binding-%%-GO:0004697-&&-protein kinase C activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0004699-&&-calcium-independent protein kinase C activity-%%-GO:0046872-&&-metal ion binding	G:9606:PRKCH			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	PRKCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKCH	0.36924777	0.11666667	18	5	FALSE	PRKCH	PRKCH	176.9375	0	17	0	0.71529857	FALSE	1	PRKCH	22112	0.09177051
787862	taxon:9606	2.7047424	8.62E-05	178695	1902	mannan binding lectin serine peptidase 1	gene	biological_process-&-1&-GO:0001867-&&-complement activation, lectin pathway-%%-GO:0006956-&&-complement activation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:MASP1			KEGG-&-1&-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	MASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MASP1	0.36972098	0.06535948	18	4	FALSE	MASP1	MASP1	155.3333333	0	18	0	0.71587627	FALSE	0	MASP1	106698	0.07893247
788032	taxon:9606	2.87994328	1.08E-05	178329	1902	RAR related orphan receptor B	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0046548-&&-retinal rod cell development-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0035881-&&-amacrine cell differentiation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0043401-&&-steroid hormone mediated signaling pathway-%%-GO:0046549-&&-retinal cone cell development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0007601-&&-visual perception-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0030522-&&-intracellular receptor signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding	G:9606:RORB			KEGG-&-1&-hsa04710-&&-Circadian rhythm	RORB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RORB	0.34722906	0.11111111	18	4	FALSE	RORB	RORB	91.94444444	0	18	0	0.68667612	FALSE	0	RORB	16084	0.08995747
788130	taxon:9606	2.82448401	1.17E-05	178192	1902	protein tyrosine phosphatase, receptor type Z1	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007417-&&-central nervous system development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0070445-&&-regulation of oligodendrocyte progenitor proliferation-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0007611-&&-learning or memory-%%-GO:0007409-&&-axonogenesis|cellular_component-&-1&-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0072534-&&-perineuronal net-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRZ1			KEGG-&-1&-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	PTPRZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRZ1	0.35404697	0.15833333	18	4	FALSE	PTPRZ1	PTPRZ1	112.75	0	17	0	0.69591933	FALSE	1	PTPRZ1	16284	0.09121759
788153	taxon:9606	2.80541988	2.13E-05	178152	1902	RAB13, member RAS oncogene family	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0015031-&&-protein transport-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0097368-&&-establishment of Sertoli cell barrier-%%-GO:0010737-&&-protein kinase A signaling-%%-GO:0032456-&&-endocytic recycling-%%-GO:0031175-&&-neuron projection development-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0030866-&&-cortical actin cytoskeleton organization-%%-GO:0016197-&&-endosomal transport-%%-GO:1902463-&&-protein localization to cell leading edge-%%-GO:0044795-&&-trans-Golgi network to recycling endosome transport-%%-GO:0070830-&&-bicellular tight junction assembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005829-&&-cytosol-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0030139-&&-endocytic vesicle-%%-GO:0030027-&&-lamellipodium-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0055037-&&-recycling endosome-%%-GO:0032593-&&-insulin-responsive compartment-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:RAB13			KEGG-&-1&-hsa04530-&&-Tight junction	RAB13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB13	0.35645288	0.12418301	18	5	FALSE	RAB13	RAB13	161.8333333	0	18	0	0.69909669	FALSE	0	RAB13	28068	0.11668672
788157	taxon:9606	2.67606743	4.22E-05	178151	1902	RAB27A, member RAS oncogene family	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0061024-&&-membrane organization-%%-GO:0043316-&&-cytotoxic T cell degranulation-%%-GO:1903307-&&-positive regulation of regulated secretory pathway-%%-GO:0007596-&&-blood coagulation-%%-GO:1990182-&&-exosomal secretion-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097278-&&-complement-dependent cytotoxicity-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0006605-&&-protein targeting-%%-GO:0032400-&&-melanosome localization-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0036257-&&-multivesicular body organization-%%-GO:0006887-&&-exocytosis-%%-GO:0048489-&&-synaptic vesicle transport-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0071985-&&-multivesicular body sorting pathway-%%-GO:1903435-&&-positive regulation of constitutive secretory pathway-%%-GO:0032402-&&-melanosome transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043320-&&-natural killer cell degranulation-%%-GO:0019882-&&-antigen processing and presentation|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0035580-&&-specific granule lumen-%%-GO:0030425-&&-dendrite-%%-GO:0030141-&&-secretory granule-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005829-&&-cytosol-%%-GO:0032585-&&-multivesicular body membrane-%%-GO:0033093-&&-Weibel-Palade body-%%-GO:0042470-&&-melanosome-%%-GO:0070382-&&-exocytic vesicle-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019003-&&-GDP binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding	G:9606:RAB27A				RAB27A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB27A	0.37368266	0.03921569	18	5	FALSE	RAB27A	RAB27A	166.5	0	18	0	0.72065543	FALSE	0	RAB27A	52972	0.07905881
788163	taxon:9606	2.76823696	1.58E-05	178143	1902	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0021894-&&-cerebral cortex GABAergic interneuron development-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0014041-&&-regulation of neuron maturation-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0031175-&&-neuron projection development-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0051932-&&-synaptic transmission, GABAergic-%%-GO:0030031-&&-cell projection assembly-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0071944-&&-cell periphery-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0012505-&&-endomembrane system-%%-GO:0030426-&&-growth cone-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0031941-&&-filamentous actin-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:RAC3			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04310-&&-Wnt signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05416-&&-Viral myocarditis-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04520-&&-Adherens junction	RAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAC3	0.36124075	0.05228758	18	4	FALSE	RAC3	RAC3	125.8333333	0	18	0	0.70529384	FALSE	0	RAC3	21940	0.07952623
788393	taxon:9606	2.76697652	3.63E-05	177750	1902	signal transducer and activator of transcription 4	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:STAT4			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05161-&&-Hepatitis B-%%-hsa04217-&&-Necroptosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation	STAT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAT4	0.36140531	0.1	18	4	FALSE	STAT4	STAT4	135.875	0	17	0	0.70550391	FALSE	1	STAT4	35806	0.08691469
788467	taxon:9606	2.57066331	1.10E-05	177586	1902	snail family transcriptional repressor 2	gene	biological_process-&-1&-GO:0043473-&&-pigmentation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0045667-&&-regulation of osteoblast differentiation-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0035921-&&-desmosome disassembly-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060429-&&-epithelium development-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:2000811-&&-negative regulation of anoikis-%%-GO:0006933-&&-negative regulation of cell adhesion involved in substrate-bound cell migration-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:2000647-&&-negative regulation of stem cell proliferation-%%-GO:0060693-&&-regulation of branching involved in salivary gland morphogenesis-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0070563-&&-negative regulation of vitamin D receptor signaling pathway-%%-GO:0014032-&&-neural crest cell development-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0060021-&&-palate development-%%-GO:1900387-&&-negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0032642-&&-regulation of chemokine production-%%-GO:0003273-&&-cell migration involved in endocardial cushion formation-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:SNAI2	SNAI2	TRUE	KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa04520-&&-Adherens junction	SNAI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAI2	0.38900466	0.22875817	18	4	FALSE	SNAI2	SNAI2	266.6111111	0	18	0	0.73822278	FALSE	0	SNAI2	27822	0.09626419
788505	taxon:9606	2.72522452	1.81E-05	177537	1902	syntrophin beta 2	gene	cellular_component-&-1&-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0045202-&&-synapse-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:SNTB2				SNTB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNTB2	0.36694224	0.075	18	4	FALSE	SNTB2	SNTB2	146.9375	0	17	0	0.71246258	FALSE	1	SNTB2	26582	0.07966286
788527	taxon:9606	2.80132346	4.72E-06	177500	1902	Spi-B transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:SPIB				SPIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPIB	0.35697413	0.35	18	5	FALSE	SPIB	SPIB	161.0625	0	17	0	0.69977942	FALSE	1	SPIB	8522	0.11346018
788690	taxon:9606	2.72837561	2.92E-05	177175	1902	C-type lectin domain family 3 member B	gene	biological_process-&-1&-GO:0001503-&&-ossification-%%-GO:0010756-&&-positive regulation of plasminogen activation-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0030282-&&-bone mineralization-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001652-&&-granular component-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0036143-&&-kringle domain binding-%%-GO:0008201-&&-heparin binding	G:9606:CLEC3B				CLEC3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLEC3B	0.36651845	0.08333333	18	4	FALSE	CLEC3B	CLEC3B	154.9375	0	17	0	0.7119374	FALSE	1	CLEC3B	31230	0.08595053
788733	taxon:9606	2.91035135	1.16E-05	160697	1902	coiled-coil domain containing 36	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007129-&&-synapsis-%%-GO:0042138-&&-meiotic DNA double-strand break formation-%%-GO:0048477-&&-oogenesis-%%-GO:0060629-&&-regulation of homologous chromosome segregation-%%-GO:0006310-&&-DNA recombination|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC36				CCDC36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC36	0.34360113	0.03921569	18	4	FALSE	CCDC36	CCDC36	57.61111111	0	18	0	0.68160811	FALSE	0	CCDC36	12790	0.06947824
788754	taxon:9606	2.72932094	1.09E-05	177011	1902	zinc finger protein 131	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF131				ZNF131	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF131	0.3663915	0.10457516	18	5	FALSE	ZNF131	ZNF131	146.2222222	0	18	0	0.71177984	FALSE	0	ZNF131	16354	0.08
788791	taxon:9606	2.89711675	1.31E-05	176884	1902	aldehyde dehydrogenase 5 family member A1	gene	biological_process-&-1&-GO:0006650-&&-glycerophospholipid metabolic process-%%-GO:0006678-&&-glucosylceramide metabolic process-%%-GO:0006105-&&-succinate metabolic process-%%-GO:0042135-&&-neurotransmitter catabolic process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006083-&&-acetate metabolic process-%%-GO:0006536-&&-glutamate metabolic process-%%-GO:0006541-&&-glutamine metabolic process-%%-GO:0007417-&&-central nervous system development-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0009450-&&-gamma-aminobutyric acid catabolic process-%%-GO:0022904-&&-respiratory electron transport chain-%%-GO:0009791-&&-post-embryonic development-%%-GO:0006681-&&-galactosylceramide metabolic process-%%-GO:0046459-&&-short-chain fatty acid metabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004777-&&-succinate-semialdehyde dehydrogenase (NAD+) activity-%%-GO:0009013-&&-succinate-semialdehyde dehydrogenase [NAD(P)+] activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:ALDH5A1			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00650-&&-Butanoate metabolism	ALDH5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH5A1	0.34517076	0.07189542	18	4	FALSE	ALDH5A1	ALDH5A1	63.05555556	0	18	0	0.68381388	FALSE	0	ALDH5A1	14026	0.07318812
789004	taxon:9606	2.78068379	1.08E-05	176413	1902	T-cell leukemia/lymphoma 1A	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:TCL1A			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	TCL1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCL1A	0.35962377	0.11666667	18	4	FALSE	TCL1A	TCL1A	141.0625	0	17	0	0.70321937	FALSE	1	TCL1A	16014	0.09397963
789062	taxon:9606	2.81124941	6.00E-06	159879	1902	ZFP91-CNTF readthrough (NMD candidate)	gene		G:9606:ZFP91-CNTF				ZFP91-CNTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFP91-CNTF	0.35571373	0.11764706	18	5	FALSE	ZFP91-CNTF	ZFP91-CNTF	156.1111111	0	18	0	0.6981251	FALSE	0	ZFP91-CNTF	14132	0.10799261
789139	taxon:9606	2.76713408	6.40E-06	176125	1902	TATA-box binding protein associated factor, RNA polymerase I subunit C	gene	biological_process-&-1&-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006360-&&-transcription from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006356-&&-regulation of transcription from RNA polymerase I promoter-%%-GO:0045815-&&-positive regulation of gene expression, epigenetic-%%-GO:0006363-&&-termination of RNA polymerase I transcription|cellular_component-&-1&-GO:0000120-&&-RNA polymerase I transcription factor complex-%%-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001164-&&-RNA polymerase I CORE element sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TAF1C				TAF1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAF1C	0.36138473	0.26797386	18	4	FALSE	TAF1C	TAF1C	149.1111111	0	18	0	0.70547765	FALSE	0	TAF1C	13884	0.0919304
789150	taxon:9606	2.75153616	1.89E-05	176099	1902	NFS1, cysteine desulfurase	gene	biological_process-&-1&-GO:0000096-&&-sulfur amino acid metabolic process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0006777-&&-Mo-molybdopterin cofactor biosynthetic process-%%-GO:0044571-&&-[2Fe-2S] cluster assembly-%%-GO:0018283-&&-iron incorporation into metallo-sulfur cluster-%%-GO:0032324-&&-molybdopterin cofactor biosynthetic process-%%-GO:0044281-&&-small molecule metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031071-&&-cysteine desulfurase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0051536-&&-iron-sulfur cluster binding-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:NFS1			KEGG-&-1&-hsa04122-&&-Sulfur relay system-%%-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways	NFS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFS1	0.36343335	0.07843137	18	4	FALSE	NFS1	NFS1	142.7222222	0	18	0	0.70807731	FALSE	0	NFS1	29266	0.0838735
789157	taxon:9606	2.825902	2.58E-05	176081	1902	DIRAS family GTPase 3	gene	biological_process-&-1&-GO:0006349-&&-regulation of gene expression by genetic imprinting-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding	G:9606:DIRAS3				DIRAS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIRAS3	0.35386931	0.07189542	18	5	FALSE	DIRAS3	DIRAS3	94.5	0	18	0	0.695683	FALSE	0	DIRAS3	27464	0.07740376
789420	taxon:9606	2.83976682	8.27E-06	175520	1902	PCNA clamp associated factor	gene	biological_process-&-1&-GO:0009411-&&-response to UV-%%-GO:0019985-&&-translesion synthesis-%%-GO:0006260-&&-DNA replication-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051297-&&-centrosome organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:PCLAF				PCLAF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCLAF	0.35214159	0.05228758	18	4	FALSE	PCLAF	PCLAF	94.55555556	0	18	0	0.6933722	FALSE	0	PCLAF	11554	0.08038936
789455	taxon:9606	2.58799433	1.80E-05	159047	1902	heat shock protein 90 alpha family class B member 2, pseudogene	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006950-&&-response to stress-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function-%%-GO:0051082-&&-unfolded protein binding	G:9606:HSP90AB2P				HSP90AB2P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90AB2P	0.38639961	0.16339869	18	4	FALSE	HSP90AB2P	HSP90AB2P	333.7777778	0	18	0	0.73533428	FALSE	0	HSP90AB2P	39764	0.12530261
789545	taxon:9606	2.63084922	1.30E-05	175220	1902	STE20 like kinase	gene	biological_process-&-1&-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031252-&&-cell leading edge|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding	G:9606:SLK			KEGG-&-1&-hsa04114-&&-Oocyte meiosis	SLK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLK	0.3801054	0.11764706	18	4	FALSE	SLK	SLK	216.6666667	0	18	0	0.7281918	FALSE	0	SLK	23904	0.08975954
789591	taxon:9606	2.7778478	8.25E-06	175109	1902	SPT7-like STAGA complex gamma subunit	gene	biological_process-&-1&-GO:0051457-&&-maintenance of protein location in nucleus-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030914-&&-STAGA complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:SUPT7L				SUPT7L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUPT7L	0.35999093	0.45098039	18	4	FALSE	SUPT7L	SUPT7L	138.2777778	0	18	0	0.70369203	FALSE	0	SUPT7L	13942	0.08673363
789598	taxon:9606	2.65936663	1.62E-05	175093	1902	helicase with zinc finger	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:HELZ				HELZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HELZ	0.37602939	0.11111111	18	4	FALSE	HELZ	HELZ	223.5	0	18	0	0.7234389	FALSE	0	HELZ	28026	0.10039468
789624	taxon:9606	2.82605956	5.48E-06	175039	1902	caspase 8 associated protein 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0007049-&&-cell cycle-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0036337-&&-Fas signaling pathway|cellular_component-&-1&-GO:0016605-&&-PML body-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005123-&&-death receptor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0032184-&&-SUMO polymer binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0016505-&&-peptidase activator activity involved in apoptotic process	G:9606:CASP8AP2				CASP8AP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP8AP2	0.35384958	0.26666667	18	4	FALSE	CASP8AP2	CASP8AP2	124.5625	0	17	0	0.69565674	FALSE	1	CASP8AP2	9098	0.10077872
789635	taxon:9606	2.72916338	8.50E-06	175016	1902	polycomb group ring finger 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PCGF3			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	PCGF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCGF3	0.36641265	0.40833333	18	5	FALSE	PCGF3	PCGF3	189.375	0	17	0	0.7118061	FALSE	1	PCGF3	15442	0.10274159
789692	taxon:9606	2.57239641	5.77E-05	174883	1902	vesicle amine transport 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010637-&&-negative regulation of mitochondrial fusion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:VAT1				VAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VAT1	0.38874257	0.09150327	18	4	FALSE	VAT1	VAT1	247.6666667	0	18	0	0.73793393	FALSE	0	VAT1	66624	0.08918551
789809	taxon:9606	2.76839452	7.95E-06	174614	1902	stromal antigen 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005694-&&-chromosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:STAG1			KEGG-&-1&-hsa04110-&&-Cell cycle	STAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAG1	0.36122019	0.26143791	18	4	FALSE	STAG1	STAG1	145.1111111	0	18	0	0.70526758	FALSE	0	STAG1	15918	0.08910046
789895	taxon:9606	2.72995116	7.36E-06	174408	1902	tripartite motif containing 3	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0030425-&&-dendrite-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:TRIM3				TRIM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM3	0.36630692	0.09166667	18	4	FALSE	TRIM3	TRIM3	163.9375	0	17	0	0.71167481	FALSE	1	TRIM3	14218	0.08962781
789961	taxon:9606	2.6817394	6.52E-05	174236	1902	lysophospholipase II	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0002084-&&-protein depalmitoylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008474-&&-palmitoyl-(protein) hydrolase activity-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0045296-&&-cadherin binding	G:9606:LYPLA2			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism	LYPLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYPLA2	0.37289231	0.16339869	18	4	FALSE	LYPLA2	LYPLA2	194.9444444	0	18	0	0.7197101	FALSE	0	LYPLA2	59274	0.09239044
790089	taxon:9606	2.50386009	3.50E-05	173900	1902	La ribonucleoprotein domain family member 4B	gene	biological_process-&-1&-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0042788-&&-polysomal ribosome|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LARP4B				LARP4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARP4B	0.39938334	0.24183007	18	4	FALSE	LARP4B	LARP4B	380.8888889	0	18	0	0.74935665	FALSE	0	LARP4B	49264	0.11932867
790215	taxon:9606	2.57665039	3.52E-05	173614	1902	neurochondrin	gene	biological_process-&-1&-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0031175-&&-neuron projection development-%%-GO:0045453-&&-bone resorption|cellular_component-&-1&-GO:0043025-&&-neuronal cell body-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NCDN				NCDN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCDN	0.38810077	0.09803922	18	4	FALSE	NCDN	NCDN	245.8888889	0	18	0	0.73722494	FALSE	0	NCDN	48094	0.09023186
790263	taxon:9606	2.71955254	6.34E-06	173480	1902	SIK family kinase 3	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:SIK3				SIK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIK3	0.36770755	0.24183007	18	4	FALSE	SIK3	SIK3	204.2777778	0	18	0	0.71340791	FALSE	0	SIK3	12958	0.11077953
790282	taxon:9606	2.93083346	1.13E-05	173450	1902	tudor domain containing 7	gene	biological_process-&-1&-GO:0070306-&&-lens fiber cell differentiation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0010608-&&-posttranscriptional regulation of gene expression|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0033391-&&-chromatoid body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:TDRD7				TDRD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TDRD7	0.34119987	0.025	18	4	FALSE	TDRD7	TDRD7	66.3125	0	17	0	0.67819442	FALSE	1	TDRD7	12898	0.09139972
790301	taxon:9606	2.62423192	2.83E-05	173381	1902	F-box and leucine rich repeat protein 2	gene	biological_process-&-1&-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006513-&&-protein monoubiquitination-%%-GO:0006508-&&-proteolysis-%%-GO:0016032-&&-viral process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019903-&&-protein phosphatase binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0036312-&&-phosphatidylinositol 3-kinase regulatory subunit binding	G:9606:FBXL2				FBXL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL2	0.38106388	0.08496732	18	4	FALSE	FBXL2	FBXL2	214.2777778	0	18	0	0.72929468	FALSE	0	FBXL2	40826	0.08794773
790341	taxon:9606	2.57365685	1.98E-05	173281	1902	SH2B adaptor protein 1	gene	biological_process-&-1&-GO:0030032-&&-lamellipodium assembly-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:2000278-&&-regulation of DNA biosynthetic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035591-&&-signaling adaptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:SH2B1			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	SH2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2B1	0.38855219	0.325	18	4	FALSE	SH2B1	SH2B1	272.625	0	17	0	0.73772386	FALSE	1	SH2B1	27064	0.09930758
790350	taxon:9606	2.91082401	1.83E-05	173255	1902	triokinase and FMN cyclase	gene	biological_process-&-1&-GO:0039534-&&-negative regulation of MDA-5 signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0061624-&&-fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:0044262-&&-cellular carbohydrate metabolic process-%%-GO:0006071-&&-glycerol metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004371-&&-glycerone kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0034012-&&-FAD-AMP lyase (cyclizing) activity-%%-GO:0005515-&&-protein binding-%%-GO:0050354-&&-triokinase activity	G:9606:TKFC			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa04622-&&-RIG-I-like receptor signaling pathway	TKFC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TKFC	0.34354533	0.10457516	18	4	FALSE	TKFC	TKFC	57.38888889	0	18	0	0.68152933	FALSE	0	TKFC	17938	0.06973274
790382	taxon:9606	2.72065543	2.08E-05	173160	1902	acyl-CoA thioesterase 9	gene	biological_process-&-1&-GO:0006637-&&-acyl-CoA metabolic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0047617-&&-acyl-CoA hydrolase activity-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0003986-&&-acetyl-CoA hydrolase activity	G:9606:ACOT9				ACOT9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACOT9	0.36755849	0.09803922	18	4	FALSE	ACOT9	ACOT9	167.2777778	0	18	0	0.7132241	FALSE	0	ACOT9	34120	0.08842396
790410	taxon:9606	2.739562	9.34E-06	173087	1902	G1 to S phase transition 2	gene	biological_process-&-1&-GO:0006415-&&-translational termination-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0002184-&&-cytoplasmic translational termination-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0018444-&&-translation release factor complex|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003747-&&-translation release factor activity	G:9606:GSPT2			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	GSPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSPT2	0.36502185	0.31372549	18	5	FALSE	GSPT2	GSPT2	135.5555556	0	18	0	0.710073	FALSE	0	GSPT2	16646	0.07712009
790429	taxon:9606	2.81282496	2.18E-05	173004	1902	integrin subunit beta 1 binding protein 2	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:ITGB1BP2				ITGB1BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB1BP2	0.35551448	0.03921569	18	4	FALSE	ITGB1BP2	ITGB1BP2	91.94444444	0	18	0	0.69786251	FALSE	0	ITGB1BP2	21774	0.07065637
790450	taxon:9606	2.84276036	9.85E-06	172817	1902	RAD54 homolog B (S. cerevisiae)	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006312-&&-mitotic recombination-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0000724-&&-double-strand break repair via homologous recombination|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0015616-&&-DNA translocase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003678-&&-DNA helicase activity-%%-GO:0003724-&&-RNA helicase activity	G:9606:RAD54B			KEGG-&-1&-hsa03440-&&-Homologous recombination	RAD54B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAD54B	0.35177077	0.04166667	18	5	FALSE	RAD54B	RAD54B	101.9375	0	17	0	0.69287327	FALSE	1	RAD54B	14860	0.0888475
790473	taxon:9606	2.81550339	1.61E-05	172752	1902	erythroid differentiation regulatory factor 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:EDRF1				EDRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EDRF1	0.35517627	0.04575163	18	4	FALSE	EDRF1	EDRF1	91.05555556	0	18	0	0.6974161	FALSE	0	EDRF1	18356	0.06974359
790484	taxon:9606	2.67433433	2.28E-05	172724	1902	interferon regulatory factor 2 binding protein 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016740-&&-transferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:IRF2BP1				IRF2BP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF2BP1	0.37392483	0.04575163	18	4	FALSE	IRF2BP1	IRF2BP1	178.2777778	0	18	0	0.72094428	FALSE	0	IRF2BP1	37744	0.08231786
790528	taxon:9606	2.86229715	1.27E-05	172595	1902	endoplasmic reticulum lectin 1	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0055085-&&-transmembrane transport-%%-GO:1904153-&&-negative regulation of retrograde protein transport, ER to cytosol-%%-GO:0036503-&&-ERAD pathway|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0001948-&&-glycoprotein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:ERLEC1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	ERLEC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERLEC1	0.34936974	0.18954248	18	4	FALSE	ERLEC1	ERLEC1	81	0	18	0	0.68961714	FALSE	0	ERLEC1	13776	0.07570551
790545	taxon:9606	2.74192532	1.73E-05	172535	1902	malonyl-CoA-acyl carrier protein transacylase	gene	biological_process-&-1&-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0008152-&&-metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0016740-&&-transferase activity-%%-GO:0004314-&&-[acyl-carrier-protein] S-malonyltransferase activity	G:9606:MCAT			KEGG-&-1&-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa01212-&&-Fatty acid metabolism	MCAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCAT	0.36470723	0.07843137	18	4	FALSE	MCAT	MCAT	134.9444444	0	18	0	0.70967911	FALSE	0	MCAT	25026	0.07834758
790580	taxon:9606	2.72743028	4.25E-05	172087	1902	VPS41, HOPS complex subunit	gene	biological_process-&-1&-GO:0006623-&&-protein targeting to vacuole-%%-GO:1902774-&&-late endosome to lysosome transport-%%-GO:0034058-&&-endosomal vesicle fusion-%%-GO:0042144-&&-vacuole fusion, non-autophagic-%%-GO:0006914-&&-autophagy-%%-GO:0035542-&&-regulation of SNARE complex assembly-%%-GO:0045055-&&-regulated exocytosis-%%-GO:0008333-&&-endosome to lysosome transport|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0030897-&&-HOPS complex-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0030123-&&-AP-3 adaptor complex-%%-GO:0071439-&&-clathrin complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005769-&&-early endosome-%%-GO:0033263-&&-CORVET complex|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0042802-&&-identical protein binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0008270-&&-zinc ion binding	G:9606:VPS41				VPS41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS41	0.36664549	0.1	18	4	FALSE	VPS41	VPS41	136.125	0	17	0	0.71209495	FALSE	1	VPS41	37866	0.07424222
790638	taxon:9606	2.8144005	1.42E-05	171692	1902	ubiquitin specific peptidase 53	gene	biological_process-&-1&-GO:0001508-&&-action potential-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:0008150-&&-biological_process-%%-GO:0051402-&&-neuron apoptotic process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:USP53				USP53	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP53	0.35531546	0.00653595	18	4	FALSE	USP53	USP53	90.38888889	0	18	0	0.69759992	FALSE	0	USP53	17768	0.06981279
790671	taxon:9606	2.63620608	1.46E-05	171539	1902	N-terminal Xaa-Pro-Lys N-methyltransferase 1	gene	biological_process-&-1&-GO:0016571-&&-histone methylation-%%-GO:0018011-&&-N-terminal peptidyl-alanine methylation-%%-GO:0035572-&&-N-terminal peptidyl-serine dimethylation-%%-GO:0007059-&&-chromosome segregation-%%-GO:0018012-&&-N-terminal peptidyl-alanine trimethylation-%%-GO:0035573-&&-N-terminal peptidyl-serine trimethylation-%%-GO:0018016-&&-N-terminal peptidyl-proline dimethylation-%%-GO:0018013-&&-N-terminal peptidyl-glycine methylation-%%-GO:0007051-&&-spindle organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042054-&&-histone methyltransferase activity-%%-GO:0008276-&&-protein methyltransferase activity-%%-GO:0071885-&&-N-terminal protein N-methyltransferase activity	G:9606:NTMT1				NTMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTMT1	0.37933301	0.05882353	18	5	FALSE	NTMT1	NTMT1	193.3888889	0	18	0	0.72729899	FALSE	0	NTMT1	28020	0.08184902
790684	taxon:9606	2.84149992	1.43E-05	171477	1902	myosin regulatory light chain interacting protein	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0007399-&&-nervous system development-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0031648-&&-protein destabilization-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032803-&&-regulation of low-density lipoprotein particle receptor catabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0010989-&&-negative regulation of low-density lipoprotein particle clearance|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:MYLIP			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	MYLIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYLIP	0.35192681	0.04166667	18	5	FALSE	MYLIP	MYLIP	107.9375	0	17	0	0.69308335	FALSE	1	MYLIP	18516	0.0911746
790694	taxon:9606	2.71356546	9.72E-06	171459	1902	tropomodulin 2	gene	biological_process-&-1&-GO:0007611-&&-learning or memory-%%-GO:0007270-&&-neuron-neuron synaptic transmission-%%-GO:0007399-&&-nervous system development-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0051694-&&-pointed-end actin filament capping|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005523-&&-tropomyosin binding	G:9606:TMOD2				TMOD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMOD2	0.36851884	0.09150327	18	4	FALSE	TMOD2	TMOD2	153.5555556	0	18	0	0.71440576	FALSE	0	TMOD2	16984	0.08048994
790709	taxon:9606	2.63699386	1.79E-05	171414	1902	coiled-coil domain containing 106	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC106				CCDC106	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC106	0.37921969	0.07843137	18	4	FALSE	CCDC106	CCDC106	196.8888889	0	18	0	0.72716769	FALSE	0	CCDC106	34934	0.08364066
790881	taxon:9606	2.58815188	3.74E-06	154400	1902	PPAN-P2RY11 readthrough	gene		G:9606:PPAN-P2RY11				PPAN-P2RY11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPAN-P2RY11	0.38637609	0.40522876	18	4	FALSE	PPAN-P2RY11	PPAN-P2RY11	348.7777778	0	18	0	0.73530802	FALSE	0	PPAN-P2RY11	14296	0.13055868
790886	taxon:9606	2.67906097	9.58E-06	170772	1902	nitric oxide synthase interacting protein	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:NOSIP				NOSIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOSIP	0.37326511	0.1503268	18	4	FALSE	NOSIP	NOSIP	194.2222222	0	18	0	0.7201565	FALSE	0	NOSIP	18998	0.0913371
790915	taxon:9606	2.74066488	8.82E-06	170706	1902	ESF1 nucleolar pre-rRNA processing protein homolog	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:ESF1				ESF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESF1	0.36487496	0.20261438	18	4	FALSE	ESF1	ESF1	166.0555556	0	18	0	0.70988919	FALSE	0	ESF1	15336	0.09361675
790940	taxon:9606	2.91665354	1.43E-05	170659	1902	FK506 binding protein 7	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:FKBP7				FKBP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP7	0.34285869	0.15	18	4	FALSE	FKBP7	FKBP7	73.375	0	17	0	0.68055774	FALSE	1	FKBP7	14452	0.09546793
791042	taxon:9606	2.52040334	1.45E-05	170270	1902	tRNA methyltransferase 10C, mitochondrial RNase P subunit	gene	biological_process-&-1&-GO:0000964-&&-mitochondrial RNA 5'-end processing-%%-GO:0090646-&&-mitochondrial tRNA processing-%%-GO:0070901-&&-mitochondrial tRNA methylation-%%-GO:0070131-&&-positive regulation of mitochondrial translation|cellular_component-&-1&-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016429-&&-tRNA (adenine-N1-)-methyltransferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0009019-&&-tRNA (guanine-N1-)-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:TRMT10C				TRMT10C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT10C	0.39676189	0.15686275	18	4	FALSE	TRMT10C	TRMT10C	356.1666667	0	18	0	0.74659944	FALSE	0	TRMT10C	45754	0.11496789
791057	taxon:9606	2.64250827	1.73E-05	170204	1902	OTU deubiquitinase 5	gene	biological_process-&-1&-GO:0070536-&&-protein K63-linked deubiquitination-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0061578-&&-Lys63-specific deubiquitinase activity-%%-GO:1990380-&&-Lys48-specific deubiquitinase activity-%%-GO:0101005-&&-ubiquitinyl hydrolase activity	G:9606:OTUD5			KEGG-&-1&-hsa04622-&&-RIG-I-like receptor signaling pathway	OTUD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUD5	0.37842833	0.07843137	18	4	FALSE	OTUD5	OTUD5	196.5555556	0	18	0	0.72624862	FALSE	0	OTUD5	27782	0.08467665
791079	taxon:9606	2.82637467	1.73E-05	170126	1902	Bardet-Biedl syndrome 7	gene	biological_process-&-1&-GO:0007368-&&-determination of left/right symmetry-%%-GO:0001947-&&-heart looping-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0015031-&&-protein transport-%%-GO:0007420-&&-brain development-%%-GO:0032402-&&-melanosome transport-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0008104-&&-protein localization-%%-GO:0007601-&&-visual perception-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0001654-&&-eye development-%%-GO:0051877-&&-pigment granule aggregation in cell center-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0060021-&&-palate development-%%-GO:0060173-&&-limb development-%%-GO:0046907-&&-intracellular transport|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0036064-&&-ciliary basal body-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0060170-&&-ciliary membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0034464-&&-BBSome|molecular_function-&-1&-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:BBS7				BBS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BBS7	0.35381013	0.10457516	18	4	FALSE	BBS7	BBS7	105.5555556	0	18	0	0.69560422	FALSE	0	BBS7	21434	0.08485909
791086	taxon:9606	2.64408382	1.85E-05	170110	1902	pantothenate kinase 4	gene	biological_process-&-1&-GO:0015937-&&-coenzyme A biosynthetic process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004594-&&-pantothenate kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:PANK4			KEGG-&-1&-hsa00770-&&-Pantothenate and CoA biosynthesis-%%-hsa01100-&&-Metabolic pathways	PANK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PANK4	0.37820284	0.26797386	18	4	FALSE	PANK4	PANK4	185.4444444	0	18	0	0.72598603	FALSE	0	PANK4	33802	0.07957636
791215	taxon:9606	2.55585316	1.42E-05	169712	1902	nicalin	gene	biological_process-&-1&-GO:0009966-&&-regulation of signal transduction-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0031648-&&-protein destabilization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NCLN				NCLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCLN	0.39125878	0.32679739	18	4	FALSE	NCLN	NCLN	318.6111111	0	18	0	0.74069114	FALSE	0	NCLN	44314	0.11111111
791227	taxon:9606	2.75846857	8.49E-06	169666	1902	WD repeat and SOCS box containing 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005622-&&-intracellular	G:9606:WSB2				WSB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WSB2	0.36251999	0.11111111	18	4	FALSE	WSB2	WSB2	152.9444444	0	18	0	0.70692191	FALSE	0	WSB2	16318	0.09261505
791233	taxon:9606	2.84606901	1.91E-05	169589	1902	testis expressed 11	gene	biological_process-&-1&-GO:0007060-&&-male meiosis chromosome segregation-%%-GO:0008584-&&-male gonad development-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0006311-&&-meiotic gene conversion-%%-GO:0051026-&&-chiasma assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009566-&&-fertilization-%%-GO:0007130-&&-synaptonemal complex assembly|cellular_component-&-1&-GO:0000795-&&-synaptonemal complex-%%-GO:0000801-&&-central element|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TEX11				TEX11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEX11	0.35136182	0.02614379	18	5	FALSE	TEX11	TEX11	81.11111111	0	18	0	0.69232183	FALSE	0	TEX11	19272	0.06980551
791244	taxon:9606	2.58815188	3.74E-06	169544	1902	peter pan homolog (Drosophila)	gene	biological_process-&-1&-GO:0000027-&&-ribosomal large subunit assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding	G:9606:PPAN				PPAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPAN	0.38637609	0.40522876	18	4	FALSE	PPAN	PPAN	348.7777778	0	18	0	0.73530802	FALSE	0	PPAN	14296	0.13055868
791270	taxon:9606	2.65983929	1.49E-05	169431	1902	extended synaptotagmin 2	gene	biological_process-&-1&-GO:0006897-&&-endocytosis-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0044232-&&-organelle membrane contact site-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0031227-&&-intrinsic component of endoplasmic reticulum membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding	G:9606:ESYT2				ESYT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ESYT2	0.37596256	0.075	18	4	FALSE	ESYT2	ESYT2	216.625	0	17	0	0.72336012	FALSE	1	ESYT2	31884	0.09681482
791288	taxon:9606	2.72333386	1.17E-05	169320	1902	zinc finger and BTB domain containing 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB2				ZBTB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB2	0.36719699	0.17647059	18	4	FALSE	ZBTB2	ZBTB2	191.3333333	0	18	0	0.71277769	FALSE	0	ZBTB2	20218	0.1015519
791313	taxon:9606	2.61792973	1.10E-05	169223	1902	BBX, HMG-box containing	gene	biological_process-&-1&-GO:0060348-&&-bone development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding	G:9606:BBX				BBX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BBX	0.38198122	0.06535948	18	4	FALSE	BBX	BBX	259.2777778	0	18	0	0.73034504	FALSE	0	BBX	30112	0.10455403
791335	taxon:9606	2.66960769	1.24E-05	169105	1902	zinc finger MIZ-type containing 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0007296-&&-vitellogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0007569-&&-cell aging-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0048589-&&-developmental growth-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:ZMIZ1				ZMIZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMIZ1	0.37458687	0.24836601	18	4	FALSE	ZMIZ1	ZMIZ1	206.6111111	0	18	0	0.72173205	FALSE	0	ZMIZ1	19598	0.09444698
791358	taxon:9606	2.60264692	8.29E-06	169018	1902	chromosome transmission fidelity factor 18	gene	biological_process-&-1&-GO:0006260-&&-DNA replication-%%-GO:0007049-&&-cell cycle-%%-GO:1900264-&&-positive regulation of DNA-directed DNA polymerase activity|cellular_component-&-1&-GO:0031390-&&-Ctf18 RFC-like complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0043142-&&-single-stranded DNA-dependent ATPase activity-%%-GO:0003689-&&-DNA clamp loader activity-%%-GO:0005515-&&-protein binding	G:9606:CHTF18				CHTF18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHTF18	0.38422423	0.43137255	18	4	FALSE	CHTF18	CHTF18	268.6666667	0	18	0	0.73289218	FALSE	0	CHTF18	15622	0.10395167
791405	taxon:9606	2.59886561	2.85E-05	168771	1902	microtubule associated monooxygenase, calponin and LIM domain containing 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030042-&&-actin filament depolymerization-%%-GO:0019417-&&-sulfur oxidation-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005882-&&-intermediate filament-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016709-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003779-&&-actin binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0071949-&&-FAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:MICAL1				MICAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MICAL1	0.38478327	0.19607843	18	4	FALSE	MICAL1	MICAL1	232.6111111	0	18	0	0.7335224	FALSE	0	MICAL1	43074	0.08949192
791431	taxon:9606	2.57271152	1.71E-05	168668	1902	MARCKS like 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MARCKSL1			KEGG-&-1&-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa05140-&&-Leishmaniasis	MARCKSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCKSL1	0.38869496	0.08496732	18	4	FALSE	MARCKSL1	MARCKSL1	264.8888889	0	18	0	0.73788141	FALSE	0	MARCKSL1	36222	0.09592297
791434	taxon:9606	2.64266583	1.38E-05	168666	1902	UPF3 regulator of nonsense transcripts homolog A (yeast)	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0051028-&&-mRNA transport-%%-GO:0006913-&&-nucleocytoplasmic transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0035145-&&-exon-exon junction complex-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005487-&&-nucleocytoplasmic transporter activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0000166-&&-nucleotide binding	G:9606:UPF3A			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03015-&&-mRNA surveillance pathway	UPF3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPF3A	0.37840577	0.26143791	18	4	FALSE	UPF3A	UPF3A	185.6111111	0	18	0	0.72622236	FALSE	0	UPF3A	24256	0.07940925
791436	taxon:9606	2.80447455	6.83E-06	168648	1902	pyrroline-5-carboxylate reductase-like	gene	biological_process-&-1&-GO:0055129-&&-L-proline biosynthetic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004735-&&-pyrroline-5-carboxylate reductase activity-%%-GO:0005515-&&-protein binding	G:9606:PYCRL			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	PYCRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYCRL	0.35657303	0.225	18	5	FALSE	PYCRL	PYCRL	145.5	0	17	0	0.69925424	FALSE	1	PYCRL	10930	0.10150245
791449	taxon:9606	2.63132188	8.04E-06	168594	1902	CUE domain containing 2	gene	biological_process-&-1&-GO:1900016-&&-negative regulation of cytokine production involved in inflammatory response-%%-GO:0010936-&&-negative regulation of macrophage cytokine production|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CUEDC2				CUEDC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUEDC2	0.38003712	0.17647059	18	4	FALSE	CUEDC2	CUEDC2	223.1111111	0	18	0	0.72811302	FALSE	0	CUEDC2	19040	0.09352434
791466	taxon:9606	2.66724437	6.79E-06	168521	1902	mitogen-activated protein kinase associated protein 1	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0021762-&&-substantia nigra development-%%-GO:0038203-&&-TORC2 signaling-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0031098-&&-stress-activated protein kinase signaling cascade-%%-GO:0030950-&&-establishment or maintenance of actin cytoskeleton polarity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0031932-&&-TORC2 complex|molecular_function-&-1&-GO:0017016-&&-Ras GTPase binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0043325-&&-phosphatidylinositol-3,4-bisphosphate binding-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0070300-&&-phosphatidic acid binding	G:9606:MAPKAP1			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	MAPKAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPKAP1	0.37491878	0.29411765	18	4	FALSE	MAPKAP1	MAPKAP1	205.0555556	0	18	0	0.72212594	FALSE	0	MAPKAP1	16098	0.09407985
791536	taxon:9606	2.64392626	1.23E-05	168212	1902	tensin 3	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0016477-&&-cell migration-%%-GO:0048286-&&-lung alveolus development|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TNS3				TNS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNS3	0.37822537	0.24836601	18	4	FALSE	TNS3	TNS3	207.1666667	0	18	0	0.72601229	FALSE	0	TNS3	25890	0.089751
791631	taxon:9606	2.63573342	3.12E-05	167735	1902	lysophosphatidylcholine acyltransferase 1	gene	biological_process-&-1&-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0008654-&&-phospholipid biosynthetic process-%%-GO:2001246-&&-negative regulation of phosphatidylcholine biosynthetic process-%%-GO:0036151-&&-phosphatidylcholine acyl-chain remodeling-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0036148-&&-phosphatidylglycerol acyl-chain remodeling-%%-GO:0019432-&&-triglyceride biosynthetic process-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0043129-&&-surfactant homeostasis|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005811-&&-lipid particle-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0047144-&&-2-acylglycerol-3-phosphate O-acyltransferase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0003841-&&-1-acylglycerol-3-phosphate O-acyltransferase activity-%%-GO:0047184-&&-1-acylglycerophosphocholine O-acyltransferase activity-%%-GO:0047191-&&-1-alkylglycerophosphocholine O-acyltransferase activity-%%-GO:0047192-&&-1-alkylglycerophosphocholine O-acetyltransferase activity-%%-GO:0047159-&&-1-alkenylglycerophosphocholine O-acyltransferase activity	G:9606:LPCAT1			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00565-&&-Ether lipid metabolism	LPCAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPCAT1	0.37940104	0.07843137	18	4	FALSE	LPCAT1	LPCAT1	194.6111111	0	18	0	0.72737776	FALSE	0	LPCAT1	38128	0.08214705
791651	taxon:9606	2.80699543	8.07E-06	167575	1902	family with sequence similarity 83 member D	gene	biological_process-&-1&-GO:1902808-&&-positive regulation of cell cycle G1/S phase transition-%%-GO:0008283-&&-cell proliferation-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0016477-&&-cell migration-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0042176-&&-regulation of protein catabolic process-%%-GO:0051310-&&-metaphase plate congression-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:1902480-&&-protein localization to mitotic spindle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0097431-&&-mitotic spindle pole|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019894-&&-kinesin binding-%%-GO:0008017-&&-microtubule binding	G:9606:FAM83D				FAM83D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM83D	0.35625281	0.1372549	18	4	FALSE	FAM83D	FAM83D	114.2777778	0	18	0	0.69883409	FALSE	0	FAM83D	14240	0.08522114
791678	taxon:9606	2.76004412	4.51E-06	167463	1902	DDB1 and CUL4 associated factor 11	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0080008-&&-Cul4-RING E3 ubiquitin ligase complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DCAF11				DCAF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCAF11	0.36231305	0.58823529	18	4	FALSE	DCAF11	DCAF11	182.7222222	0	18	0	0.70665931	FALSE	0	DCAF11	9262	0.11189406
791693	taxon:9606	2.81124941	6.00E-06	167401	1902	ZFP91 zinc finger protein	gene	biological_process-&-1&-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0007250-&&-activation of NF-kappaB-inducing kinase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:ZFP91				ZFP91	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFP91	0.35571373	0.11764706	18	5	FALSE	ZFP91	ZFP91	156.1111111	0	18	0	0.6981251	FALSE	0	ZFP91	14132	0.10799261
791730	taxon:9606	2.68520561	7.39E-05	167142	1902	transmembrane and ubiquitin like domain containing 1	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TMUB1				TMUB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMUB1	0.37241096	0.09150327	18	4	FALSE	TMUB1	TMUB1	153.3888889	0	18	0	0.7191324	FALSE	0	TMUB1	67774	0.07477067
791778	taxon:9606	2.76792185	6.72E-06	166933	1902	chromodomain helicase DNA binding protein 6	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0036091-&&-positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005665-&&-DNA-directed RNA polymerase II, core complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001221-&&-transcription cofactor binding-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0008026-&&-ATP-dependent helicase activity	G:9606:CHD6				CHD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD6	0.36128188	0.06535948	18	4	FALSE	CHD6	CHD6	161.2222222	0	18	0	0.70534636	FALSE	0	CHD6	15134	0.09993099
791799	taxon:9606	2.70222152	4.27E-06	166812	1902	AKT1 substrate 1	gene	biological_process-&-1&-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0043523-&&-regulation of neuron apoptotic process-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:0038202-&&-TORC1 signaling-%%-GO:1900034-&&-regulation of cellular response to heat|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031931-&&-TORC1 complex|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AKT1S1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species	AKT1S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT1S1	0.37006589	0.275	18	4	FALSE	AKT1S1	AKT1S1	229.0625	0	17	0	0.71629641	FALSE	1	AKT1S1	10492	0.1163574
791940	taxon:9606	2.67260123	1.82E-05	166455	1902	myosin light chain kinase 2	gene	biological_process-&-1&-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0014816-&&-skeletal muscle satellite cell differentiation-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0032971-&&-regulation of muscle filament sliding-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006941-&&-striated muscle contraction-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0030017-&&-sarcomere-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004687-&&-myosin light chain kinase activity-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYLK2			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MYLK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYLK2	0.37416731	0.11764706	18	4	FALSE	MYLK2	MYLK2	186.1666667	0	18	0	0.72123313	FALSE	0	MYLK2	31786	0.08650018
791947	taxon:9606	2.68268473	2.13E-05	166436	1902	naked cuticle homolog 2	gene	biological_process-&-1&-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0010954-&&-positive regulation of protein processing-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0006887-&&-exocytosis-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0048210-&&-Golgi vesicle fusion to target membrane-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019838-&&-growth factor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NKD2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	NKD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKD2	0.37276091	0.09803922	18	4	FALSE	NKD2	NKD2	181.4444444	0	18	0	0.71955254	FALSE	0	NKD2	28732	0.08791802
792000	taxon:9606	2.79360328	7.47E-06	182748	1902	BCL tumor suppressor 7A	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:BCL7A				BCL7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL7A	0.35796063	0.55555556	18	4	FALSE	BCL7A	BCL7A	134.9444444	0	18	0	0.70106612	FALSE	0	BCL7A	12312	0.09091931
792016	taxon:9606	2.62628013	1.80E-05	166341	1902	component of oligomeric golgi complex 7	gene	biological_process-&-1&-GO:0006886-&&-intracellular protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0050821-&&-protein stabilization-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0007030-&&-Golgi organization-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0006486-&&-protein glycosylation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COG7				COG7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG7	0.38076669	0.29166667	18	4	FALSE	COG7	COG7	227.6875	0	17	0	0.72895331	FALSE	1	COG7	24428	0.09302207
792087	taxon:9606	3.20923271	7.04E-05	182642	1902	C-C motif chemokine receptor 3	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0006968-&&-cellular defense response-%%-GO:0016032-&&-viral process-%%-GO:0045766-&&-positive regulation of angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004950-&&-chemokine receptor activity-%%-GO:0016493-&&-C-C chemokine receptor activity-%%-GO:0005515-&&-protein binding	G:9606:CCR3			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCR3	0.31160096	0.025	18	5	FALSE	CCR3	CCR3	16.25	0	17	0	0.63179455	FALSE	1	CCR3	104664	0.1015625
792092	taxon:9606	2.65400977	1.93E-05	166245	1902	neuron navigator 1	gene	biological_process-&-1&-GO:0001764-&&-neuron migration-%%-GO:0001578-&&-microtubule bundle formation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043194-&&-axon initial segment-%%-GO:0005874-&&-microtubule	G:9606:NAV1				NAV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAV1	0.37678836	0.12418301	18	5	FALSE	NAV1	NAV1	177.6666667	0	18	0	0.72433171	FALSE	0	NAV1	28162	0.07906078
792167	taxon:9606	2.78430755	5.22E-06	166104	1902	pygopus family PHD finger 2	gene	biological_process-&-1&-GO:0001701-&&-in utero embryonic development-%%-GO:0030879-&&-mammary gland development-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007420-&&-brain development-%%-GO:0060021-&&-palate development-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0048589-&&-developmental growth-%%-GO:0051569-&&-regulation of histone H3-K4 methylation-%%-GO:0033599-&&-regulation of mammary gland epithelial cell proliferation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0007289-&&-spermatid nucleus differentiation-%%-GO:0001822-&&-kidney development-%%-GO:0035065-&&-regulation of histone acetylation-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:1904837-&&-beta-catenin-TCF complex assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0035034-&&-histone acetyltransferase regulator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0008270-&&-zinc ion binding	G:9606:PYGO2				PYGO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYGO2	0.35915573	0.30833333	18	4	FALSE	PYGO2	PYGO2	150.6875	0	17	0	0.70261541	FALSE	1	PYGO2	9188	0.1000166
792180	taxon:9606	2.58279502	2.02E-05	182468	1902	arginase 1	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0014075-&&-response to amine-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0009635-&&-response to herbicide-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071353-&&-cellular response to interleukin-4-%%-GO:0010043-&&-response to zinc ion-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0010963-&&-regulation of L-arginine import-%%-GO:0032964-&&-collagen biosynthetic process-%%-GO:0033197-&&-response to vitamin E-%%-GO:0060056-&&-mammary gland involution-%%-GO:0007568-&&-aging-%%-GO:0010269-&&-response to selenium ion-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0010042-&&-response to manganese ion-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001889-&&-liver development-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0030324-&&-lung development-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0043200-&&-response to amino acid-%%-GO:0048678-&&-response to axon injury-%%-GO:0019547-&&-arginine catabolic process to ornithine-%%-GO:0051597-&&-response to methylmercury-%%-GO:0042493-&&-response to drug-%%-GO:0006527-&&-arginine catabolic process-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0004053-&&-arginase activity-%%-GO:0030145-&&-manganese ion binding	G:9606:ARG1			KEGG-&-1&-hsa00220-&&-Arginine biosynthesis-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa05146-&&-Amoebiasis-%%-hsa01100-&&-Metabolic pathways	ARG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARG1	0.38717745	0.19607843	18	4	FALSE	ARG1	ARG1	365.1666667	0	18	0	0.73620083	FALSE	0	ARG1	36764	0.13379765
792193	taxon:9606	2.6135182	2.56E-05	182453	1902	ADP ribosylation factor like GTPase 1	gene	biological_process-&-1&-GO:0009404-&&-toxin metabolic process-%%-GO:0048193-&&-Golgi vesicle transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0034067-&&-protein localization to Golgi apparatus-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0007030-&&-Golgi organization-%%-GO:0031584-&&-activation of phospholipase D activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0008047-&&-enzyme activator activity	G:9606:ARL1				ARL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARL1	0.38262599	0.09150327	18	4	FALSE	ARL1	ARL1	235.5	0	18	0	0.7310803	FALSE	0	ARL1	45904	0.09329016
792203	taxon:9606	2.85567985	1.00E-05	166041	1902	basic transcription factor 3 like 4	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BTF3L4				BTF3L4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTF3L4	0.35017931	0.10457516	18	4	FALSE	BTF3L4	BTF3L4	77.83333333	0	18	0	0.69072003	FALSE	0	BTF3L4	12694	0.07012256
792230	taxon:9606	2.76193477	3.85E-05	182379	1902	ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0099132-&&-ATP hydrolysis coupled cation transmembrane transport-%%-GO:0006816-&&-calcium ion transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0031095-&&-platelet dense tubular network membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0033017-&&-sarcoplasmic reticulum membrane|molecular_function-&-1&-GO:0005388-&&-calcium-transporting ATPase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:ATP2A3			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ATP2A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP2A3	0.36206503	0.03921569	18	4	FALSE	ATP2A3	ATP2A3	138.5	0	18	0	0.7063442	FALSE	0	ATP2A3	49472	0.08461067
792264	taxon:9606	2.91523554	7.78E-06	165943	1902	transcriptional adaptor 2B	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0035066-&&-positive regulation of histone acetylation-%%-GO:0016573-&&-histone acetylation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0030914-&&-STAGA complex-%%-GO:0070461-&&-SAGA-type complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:TADA2B				TADA2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TADA2B	0.34302546	0.39215686	18	5	FALSE	TADA2B	TADA2B	73.5	0	18	0	0.68079408	FALSE	0	TADA2B	10018	0.08451605
792361	taxon:9606	2.67969119	1.95E-05	182157	1902	adaptor related protein complex 2 sigma 1 subunit	gene	biological_process-&-1&-GO:0048268-&&-clathrin coat assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0072583-&&-clathrin-dependent endocytosis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0036020-&&-endolysosome membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0035615-&&-clathrin adaptor activity-%%-GO:0005215-&&-transporter activity	G:9606:AP2S1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa05016-&&-Huntington disease-%%-hsa04721-&&-Synaptic vesicle cycle	AP2S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP2S1	0.37317733	0.35947712	18	4	FALSE	AP2S1	AP2S1	199	0	18	0	0.72005147	FALSE	0	AP2S1	24724	0.09378931
792367	taxon:9606	2.52512998	1.84E-05	165760	1902	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	gene	biological_process-&-1&-GO:0008360-&&-regulation of cell shape-%%-GO:0030037-&&-actin filament reorganization involved in cell cycle-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0007165-&&-signal transduction-%%-GO:0051270-&&-regulation of cellular component movement-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0032580-&&-Golgi cisterna membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:ARAP1			KEGG-&-1&-hsa04144-&&-Endocytosis	ARAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARAP1	0.39601922	0.12418301	18	4	FALSE	ARAP1	ARAP1	287.1111111	0	18	0	0.74581167	FALSE	0	ARAP1	35348	0.09440789
792372	taxon:9606	2.77847802	8.41E-06	165755	1902	transcriptional adaptor 1	gene	biological_process-&-1&-GO:0043966-&&-histone H3 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0030914-&&-STAGA complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000124-&&-SAGA complex|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0004402-&&-histone acetyltransferase activity	G:9606:TADA1				TADA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TADA1	0.35990927	0.60784314	18	4	FALSE	TADA1	TADA1	134.5555556	0	18	0	0.703587	FALSE	0	TADA1	15072	0.08581349
792425	taxon:9606	2.94721916	1.72E-04	182046	1902	versican	gene	biological_process-&-1&-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007417-&&-central nervous system development-%%-GO:0030208-&&-dermatan sulfate biosynthetic process-%%-GO:0008037-&&-cell recognition-%%-GO:0007155-&&-cell adhesion-%%-GO:0007275-&&-multicellular organism development-%%-GO:0001501-&&-skeletal system development-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0030206-&&-chondroitin sulfate biosynthetic process|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005540-&&-hyaluronic acid binding	G:9606:VCAN	VCAN	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	VCAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VCAN	0.3393029	0.06666667	18	5	FALSE	VCAN	VCAN	52.4375	0	17	0	0.67546347	FALSE	1	VCAN	219462	0.0724096
792453	taxon:9606	2.83614306	2.31E-05	181998	1902	cathepsin V	gene	biological_process-&-1&-GO:0048102-&&-autophagic cell death-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0046697-&&-decidualization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0007283-&&-spermatogenesis-%%-GO:1990834-&&-response to odorant-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0060008-&&-Sertoli cell differentiation-%%-GO:0009749-&&-response to glucose-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0034698-&&-response to gonadotropin-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0021675-&&-nerve development-%%-GO:0016540-&&-protein autoprocessing-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0043204-&&-perikaryon-%%-GO:0005764-&&-lysosome-%%-GO:0030141-&&-secretory granule-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005730-&&-nucleolus-%%-GO:0045177-&&-apical part of cell-%%-GO:0005902-&&-microvillus-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0042393-&&-histone binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0030984-&&-kininogen binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0016807-&&-cysteine-type carboxypeptidase activity-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:CTSV			KEGG-&-1&-hsa04210-&&-Apoptosis-%%-hsa04142-&&-Lysosome	CTSV	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSV	0.35259152	0.03267974	18	4	FALSE	CTSV	CTSV	95.22222222	0	18	0	0.69397616	FALSE	0	CTSV	27012	0.08000188
792595	taxon:9606	2.85599496	3.99E-05	181746	1902	dystrobrevin alpha	gene	biological_process-&-1&-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007165-&&-signal transduction-%%-GO:0006941-&&-striated muscle contraction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0030054-&&-cell junction-%%-GO:0043234-&&-protein complex-%%-GO:0030424-&&-axon-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:DTNA				DTNA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTNA	0.35014067	0.06535948	18	5	FALSE	DTNA	DTNA	74.94444444	0	18	0	0.69066751	FALSE	0	DTNA	36688	0.07225994
792600	taxon:9606	2.61414842	7.81E-05	181738	1902	dual specificity phosphatase 3	gene	biological_process-&-1&-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0016311-&&-dephosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0050868-&&-negative regulation of T cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0001772-&&-immunological synapse-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0033549-&&-MAP kinase phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0016791-&&-phosphatase activity-%%-GO:0019901-&&-protein kinase binding	G:9606:DUSP3			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP3	0.38253375	0.13071895	18	4	FALSE	DUSP3	DUSP3	200.5	0	18	0	0.73097526	FALSE	0	DUSP3	63394	0.08085498
792617	taxon:9606	2.69686466	9.94E-06	181714	1902	E4F transcription factor 1	gene	biological_process-&-1&-GO:0009794-&&-regulation of mitotic cell cycle, embryonic-%%-GO:0006260-&&-DNA replication-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0016032-&&-viral process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0040008-&&-regulation of growth-%%-GO:0010564-&&-regulation of cell cycle process-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005819-&&-spindle|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0016740-&&-transferase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0005515-&&-protein binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0046872-&&-metal ion binding	G:9606:E4F1				E4F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-E4F1	0.37080096	0.1503268	18	4	FALSE	E4F1	E4F1	173.6666667	0	18	0	0.71718922	FALSE	0	E4F1	19992	0.08624786
792636	taxon:9606	2.75642036	1.98E-05	181678	1902	eukaryotic translation initiation factor 2D	gene	biological_process-&-1&-GO:0032790-&&-ribosome disassembly-%%-GO:0001731-&&-formation of translation preinitiation complex-%%-GO:0002192-&&-IRES-dependent translational initiation-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0004872-&&-receptor activity	G:9606:EIF2D				EIF2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2D	0.36278937	0.08496732	18	4	FALSE	EIF2D	EIF2D	142.7777778	0	18	0	0.70726327	FALSE	0	EIF2D	25728	0.08369239
792732	taxon:9606	3.00267843	9.17E-06	181483	1902	distal-less homeobox 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060166-&&-olfactory pit development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0097376-&&-interneuron axon guidance-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0060325-&&-face morphogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0001501-&&-skeletal system development-%%-GO:0021889-&&-olfactory bulb interneuron differentiation-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0001958-&&-endochondral ossification-%%-GO:0060021-&&-palate development|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0071837-&&-HMG box domain binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:DLX5			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	DLX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLX5	0.333036	0.09166667	18	5	FALSE	DLX5	DLX5	43.0625	0	17	0	0.66622026	FALSE	1	DLX5	8130	0.085375
792735	taxon:9606	2.72490941	1.47E-05	181476	1902	dystrophia myotonica protein kinase	gene	biological_process-&-1&-GO:0010657-&&-muscle cell apoptotic process-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0014853-&&-regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction-%%-GO:0010830-&&-regulation of myotube differentiation-%%-GO:0051823-&&-regulation of synapse structural plasticity-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0014722-&&-regulation of skeletal muscle contraction by calcium ion signaling-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006998-&&-nuclear envelope organization|cellular_component-&-1&-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005640-&&-nuclear outer membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0017020-&&-myosin phosphatase regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0031072-&&-heat shock protein binding	G:9606:DMPK				DMPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMPK	0.36698468	0.04575163	18	4	FALSE	DMPK	DMPK	154.2222222	0	18	0	0.7125151	FALSE	0	DMPK	28072	0.08374205
792746	taxon:9606	2.6615724	1.88E-05	181444	1902	farnesyl-diphosphate farnesyltransferase 1	gene	biological_process-&-1&-GO:0006696-&&-ergosterol biosynthetic process-%%-GO:0008299-&&-isoprenoid biosynthetic process-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045338-&&-farnesyl diphosphate metabolic process-%%-GO:0006694-&&-steroid biosynthetic process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0004310-&&-farnesyl-diphosphate farnesyltransferase activity-%%-GO:0051996-&&-squalene synthase activity-%%-GO:0005515-&&-protein binding	G:9606:FDFT1			KEGG-&-1&-hsa00100-&&-Steroid biosynthesis-%%-hsa01100-&&-Metabolic pathways	FDFT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FDFT1	0.37571775	0.125	18	5	FALSE	FDFT1	FDFT1	214.3125	0	17	0	0.72307127	FALSE	1	FDFT1	27240	0.09741811
792836	taxon:9606	2.71514101	1.87E-05	181284	1902	EPH receptor B6	gene	biological_process-&-1&-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005003-&&-ephrin receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:EPHB6			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHB6	0.368305	0.13071895	18	4	FALSE	EPHB6	EPHB6	164.3888889	0	18	0	0.71414316	FALSE	0	EPHB6	35976	0.08669367
792891	taxon:9606	2.79218528	2.60E-04	181208	1902	coagulation factor VII	gene	biological_process-&-1&-GO:1905217-&&-response to astaxanthin-%%-GO:0010037-&&-response to carbon dioxide-%%-GO:1904612-&&-response to 2,3,7,8-tetrachlorodibenzodioxine-%%-GO:0007596-&&-blood coagulation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:1905225-&&-response to thyrotropin-releasing hormone-%%-GO:0007598-&&-blood coagulation, extrinsic pathway-%%-GO:0043627-&&-response to estrogen-%%-GO:0097068-&&-response to thyroxine-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0001666-&&-response to hypoxia-%%-GO:0032571-&&-response to vitamin K-%%-GO:0061476-&&-response to anticoagulant-%%-GO:0070723-&&-response to cholesterol-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0032355-&&-response to estradiol-%%-GO:0007623-&&-circadian rhythm-%%-GO:0010641-&&-positive regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0060416-&&-response to growth hormone-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0006465-&&-signal peptide processing-%%-GO:0016485-&&-protein processing-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:1904400-&&-response to Thyroid stimulating hormone-%%-GO:0033595-&&-response to genistein-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0030335-&&-positive regulation of cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:1905286-&&-serine-type peptidase complex|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005102-&&-receptor binding	G:9606:F7	F7	TRUE	KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F7	0.35814242	0.06666667	18	4	FALSE	F7	F7	125.1875	0	17	0	0.70130245	FALSE	1	F7	285556	0.08683936
792900	taxon:9606	2.74428864	1.02E-04	181202	1902	coagulation factor XII	gene	biological_process-&-1&-GO:0051919-&&-positive regulation of fibrinolysis-%%-GO:0045087-&&-innate immune response-%%-GO:0016540-&&-protein autoprocessing-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0002542-&&-Factor XII activation-%%-GO:0042730-&&-fibrinolysis-%%-GO:0002353-&&-plasma kallikrein-kinin cascade-%%-GO:0016485-&&-protein processing-%%-GO:0010756-&&-positive regulation of plasminogen activation-%%-GO:0031638-&&-zymogen activation-%%-GO:0051788-&&-response to misfolded protein-%%-GO:0007597-&&-blood coagulation, intrinsic pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:F12			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F12	0.36439316	0.05833333	18	4	FALSE	F12	F12	148.1875	0	17	0	0.70928523	FALSE	1	F12	113300	0.08826165
792927	taxon:9606	2.66109973	1.12E-05	181130	1902	UDP-galactose-4-epimerase	gene	biological_process-&-1&-GO:0019388-&&-galactose catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003978-&&-UDP-glucose 4-epimerase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0003974-&&-UDP-N-acetylglucosamine 4-epimerase activity	G:9606:GALE			KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	GALE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GALE	0.37578449	0.15833333	18	4	FALSE	GALE	GALE	204.3125	0	17	0	0.72315004	FALSE	1	GALE	22230	0.09242081
792946	taxon:9606	2.78714353	5.67E-05	181103	1902	FAT atypical cadherin 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007155-&&-cell adhesion-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0016477-&&-cell migration-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030175-&&-filopodium-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:FAT1				FAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAT1	0.35879028	0.01960784	18	4	FALSE	FAT1	FAT1	110.6111111	0	18	0	0.70214274	FALSE	0	FAT1	64922	0.07578544
792959	taxon:9606	2.87269576	1.96E-05	181086	1902	fibrinogen gamma chain	gene	biological_process-&-1&-GO:0072378-&&-blood coagulation, fibrin clot formation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0031639-&&-plasminogen activation-%%-GO:0009306-&&-protein secretion-%%-GO:0051592-&&-response to calcium ion-%%-GO:0007596-&&-blood coagulation-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0043623-&&-cellular protein complex assembly-%%-GO:0051258-&&-protein polymerization-%%-GO:0036345-&&-platelet maturation-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0042730-&&-fibrinolysis-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0070527-&&-platelet aggregation-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005577-&&-fibrinogen complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:FGG			KEGG-&-1&-hsa04611-&&-Platelet activation-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	FGG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGG	0.34810508	0.15	18	4	FALSE	FGG	FGG	81.25	0	17	0	0.68788404	FALSE	1	FGG	16520	0.07947304
792987	taxon:9606	2.82432645	4.82E-06	181036	1902	fms related tyrosine kinase 3	gene	biological_process-&-1&-GO:0035726-&&-common myeloid progenitor cell proliferation-%%-GO:0038084-&&-vascular endothelial growth factor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0002318-&&-myeloid progenitor cell differentiation-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0002328-&&-pro-B cell differentiation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042531-&&-positive regulation of tyrosine phosphorylation of STAT protein-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0030097-&&-hemopoiesis-%%-GO:0046651-&&-lymphocyte proliferation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0030183-&&-B cell differentiation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0001776-&&-leukocyte homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0004896-&&-cytokine receptor activity-%%-GO:0035259-&&-glucocorticoid receptor binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity	G:9606:FLT3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage	FLT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLT3	0.35406672	0.31666667	18	5	FALSE	FLT3	FLT3	143.625	0	17	0	0.69594559	FALSE	1	FLT3	9160	0.11379857
793005	taxon:9606	2.66535371	7.50E-06	164602	1902	parkin coregulated	gene	biological_process-&-1&-GO:0060548-&&-negative regulation of cell death-%%-GO:0007286-&&-spermatid development-%%-GO:0034620-&&-cellular response to unfolded protein|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0097225-&&-sperm midpiece-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0044297-&&-cell body-%%-GO:0031982-&&-vesicle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0003779-&&-actin binding-%%-GO:0051879-&&-Hsp90 protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:PACRG				PACRG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PACRG	0.37518473	0.43137255	18	4	FALSE	PACRG	PACRG	231.3888889	0	18	0	0.72244105	FALSE	0	PACRG	12602	0.10685142
793077	taxon:9606	2.78147156	9.67E-06	180802	1902	general transcription factor IIH subunit 4	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000438-&&-core TFIIH complex portion of holo TFIIH complex-%%-GO:0005634-&&-nucleus-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0004003-&&-ATP-dependent DNA helicase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity	G:9606:GTF2H4			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair	GTF2H4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2H4	0.35952192	0.44444444	18	4	FALSE	GTF2H4	GTF2H4	131.7222222	0	18	0	0.70308807	FALSE	0	GTF2H4	14876	0.08363316
793103	taxon:9606	2.70206397	1.40E-05	180725	1902	glutaryl-CoA dehydrogenase	gene	biological_process-&-1&-GO:0006554-&&-lysine catabolic process-%%-GO:0046949-&&-fatty-acyl-CoA biosynthetic process-%%-GO:0006568-&&-tryptophan metabolic process-%%-GO:0033539-&&-fatty acid beta-oxidation using acyl-CoA dehydrogenase|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004361-&&-glutaryl-CoA dehydrogenase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0000062-&&-fatty-acyl-CoA binding	G:9606:GCDH			KEGG-&-1&-hsa00380-&&-Tryptophan metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00310-&&-Lysine degradation-%%-hsa00071-&&-Fatty acid degradation	GCDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCDH	0.37008746	0.38333333	18	4	FALSE	GCDH	GCDH	181.625	0	17	0	0.71632267	FALSE	1	GCDH	27102	0.09285532
793171	taxon:9606	2.67197101	1.19E-05	164213	1902	TEPSIN, adaptor related protein complex 4 accessory protein	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016607-&&-nuclear speck-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031410-&&-cytoplasmic vesicle	G:9606:TEPSIN				TEPSIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEPSIN	0.37425556	0.06535948	18	4	FALSE	TEPSIN	TEPSIN	175.0555556	0	18	0	0.72133817	FALSE	0	TEPSIN	22276	0.08072636
787032	taxon:9606	2.75657791	5.94E-06	180196	1902	homeobox A10	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008584-&&-male gonad development-%%-GO:0060065-&&-uterus development-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0001501-&&-skeletal system development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007338-&&-single fertilization-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0007275-&&-multicellular organism development-%%-GO:0030326-&&-embryonic limb morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:HOXA10			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	HOXA10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXA10	0.36276863	0.20952381	17	4	FALSE	HOXA10	HOXA10	174.8	0	16	0	0.70723701	FALSE	1	HOXA10	12706	0.10624493
787114	taxon:9606	2.93934142	1.30E-04	180038	1902	C-X-C motif chemokine receptor 2	gene	biological_process-&-1&-GO:0042119-&&-neutrophil activation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007165-&&-signal transduction-%%-GO:0006968-&&-cellular defense response-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0038112-&&-interleukin-8-mediated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0019959-&&-interleukin-8 binding-%%-GO:0016494-&&-C-X-C chemokine receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0004918-&&-interleukin-8 receptor activity	G:9606:CXCR2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCR2	0.34021226	0.0952381	17	4	FALSE	CXCR2	CXCR2	51.8	0	16	0	0.67677643	FALSE	1	CXCR2	161118	0.08092243
787158	taxon:9606	2.651804	1.23E-05	179962	1902	lipoprotein lipase	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0034371-&&-chylomicron remodeling-%%-GO:0034372-&&-very-low-density lipoprotein particle remodeling-%%-GO:0090197-&&-positive regulation of chemokine secretion-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0009749-&&-response to glucose-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0019432-&&-triglyceride biosynthetic process-%%-GO:0010890-&&-positive regulation of sequestering of triglyceride-%%-GO:0055096-&&-low-density lipoprotein particle mediated signaling-%%-GO:0042493-&&-response to drug-%%-GO:0006644-&&-phospholipid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0009986-&&-cell surface-%%-GO:0042627-&&-chylomicron-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004620-&&-phospholipase activity-%%-GO:0004806-&&-triglyceride lipase activity-%%-GO:0034185-&&-apolipoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004465-&&-lipoprotein lipase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0017129-&&-triglyceride binding	G:9606:LPL	LPL	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa05010-&&-Alzheimer disease-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa03320-&&-PPAR signaling pathway	LPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPL	0.37710178	0.13333333	17	4	FALSE	LPL	LPL	214.5333333	0	16	0	0.72469933	FALSE	1	LPL	20206	0.09400585
787170	taxon:9606	3.12651646	2.92E-05	163551	1902	5-hydroxytryptamine receptor 3C	gene	biological_process-&-1&-GO:0098655-&&-cation transmembrane transport-%%-GO:0007165-&&-signal transduction-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0022850-&&-serotonin-gated cation-selective channel activity	G:9606:HTR3C			KEGG-&-1&-hsa04726-&&-Serotonergic synapse-%%-hsa04742-&&-Taste transduction	HTR3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTR3C	0.31984479	0.02205882	17	5	FALSE	HTR3C	HTR3C	16.41176471	0	17	0	0.64558059	FALSE	0	HTR3C	26518	0.07558966
787253	taxon:9606	2.64865291	9.47E-06	163415	1902	torsin 1A interacting protein 2	gene	biological_process-&-1&-GO:0090435-&&-protein localization to nuclear envelope-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0032781-&&-positive regulation of ATPase activity|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0001671-&&-ATPase activator activity-%%-GO:0051117-&&-ATPase binding	G:9606:TOR1AIP2				TOR1AIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOR1AIP2	0.37755041	0.375	17	4	FALSE	TOR1AIP2	TOR1AIP2	249.7058824	0	17	0	0.72522452	FALSE	0	TOR1AIP2	24308	0.10872741
787397	taxon:9606	2.79265795	1.15E-05	179500	1902	protein phosphatase 1 regulatory subunit 12B	gene	biological_process-&-1&-GO:0006937-&&-regulation of muscle contraction-%%-GO:0007165-&&-signal transduction-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031672-&&-A band-%%-GO:0005654-&&-nucleoplasm-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0008047-&&-enzyme activator activity-%%-GO:0019208-&&-phosphatase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:PPP1R12B			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04921-&&-Oxytocin signaling pathway	PPP1R12B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R12B	0.35808181	0.16911765	17	4	FALSE	PPP1R12B	PPP1R12B	145.8823529	0	17	0	0.70122368	FALSE	0	PPP1R12B	17990	0.10128446
787483	taxon:9606	2.82322357	3.10E-05	179354	1902	muskelin 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0001726-&&-ruffle-%%-GO:0005829-&&-cytosol-%%-GO:0005938-&&-cell cortex	G:9606:MKLN1				MKLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKLN1	0.35420503	0.16190476	17	4	FALSE	MKLN1	MKLN1	106.6666667	0	16	0	0.6961294	FALSE	1	MKLN1	27516	0.08286604
787589	taxon:9606	2.87112021	1.20E-05	179133	1902	neuronal differentiation 1	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0060730-&&-regulation of intestinal epithelial structure maintenance-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0048562-&&-embryonic organ morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0022008-&&-neurogenesis-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0003326-&&-pancreatic A cell fate commitment-%%-GO:0071156-&&-regulation of cell cycle arrest-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process-%%-GO:0009749-&&-response to glucose-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021542-&&-dentate gyrus development-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0003329-&&-pancreatic PP cell fate commitment-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0030073-&&-insulin secretion-%%-GO:0048666-&&-neuron development-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0021549-&&-cerebellum development-%%-GO:0035881-&&-amacrine cell differentiation-%%-GO:0048839-&&-inner ear development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0035883-&&-enteroendocrine cell differentiation|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0070888-&&-E-box binding	G:9606:NEUROD1			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young	NEUROD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEUROD1	0.34829611	0.11428571	17	5	FALSE	NEUROD1	NEUROD1	95.2	0	16	0	0.68814663	FALSE	1	NEUROD1	13022	0.09313725
787680	taxon:9606	2.89695919	3.95E-05	178966	1902	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0072672-&&-neutrophil extravasation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0007411-&&-axon guidance-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035747-&&-natural killer cell chemotaxis-%%-GO:0007165-&&-signal transduction-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0035754-&&-B cell chemotaxis-%%-GO:0042113-&&-B cell activation-%%-GO:0042110-&&-T cell activation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0001779-&&-natural killer cell differentiation-%%-GO:0016310-&&-phosphorylation-%%-GO:0006954-&&-inflammatory response-%%-GO:0002679-&&-respiratory burst involved in defense response-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0045087-&&-innate immune response-%%-GO:0001816-&&-cytokine production-%%-GO:0060374-&&-mast cell differentiation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016301-&&-kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035004-&&-phosphatidylinositol 3-kinase activity-%%-GO:0035005-&&-1-phosphatidylinositol-4-phosphate 3-kinase activity	G:9606:PIK3CD			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04360-&&-Axon guidance-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	PIK3CD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3CD	0.34518954	0.14285714	17	5	FALSE	PIK3CD	PIK3CD	83.6	0	16	0	0.68384013	FALSE	1	PIK3CD	54250	0.09889153
787712	taxon:9606	2.78241689	1.92E-05	178901	1902	plexin B1	gene	biological_process-&-1&-GO:0048675-&&-axon extension-%%-GO:1900220-&&-semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0043931-&&-ossification involved in bone maturation-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016477-&&-cell migration-%%-GO:0033689-&&-negative regulation of osteoblast proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0002116-&&-semaphorin receptor complex-%%-GO:0005622-&&-intracellular-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0017154-&&-semaphorin receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0032794-&&-GTPase activating protein binding-%%-GO:0030215-&&-semaphorin receptor binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:PLXNB1			KEGG-&-1&-hsa04360-&&-Axon guidance	PLXNB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLXNB1	0.35939977	0.19117647	17	4	FALSE	PLXNB1	PLXNB1	131.9411765	0	17	0	0.70293052	FALSE	0	PLXNB1	20366	0.08843269
787713	taxon:9606	2.85331653	2.93E-05	178903	1902	plexin A1	gene	biological_process-&-1&-GO:0021785-&&-branchiomotor neuron axon guidance-%%-GO:1990138-&&-neuron projection extension-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0014910-&&-regulation of smooth muscle cell migration-%%-GO:0060666-&&-dichotomous subdivision of terminal units involved in salivary gland branching-%%-GO:0048841-&&-regulation of axon extension involved in axon guidance|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0002116-&&-semaphorin receptor complex|molecular_function-&-1&-GO:0017154-&&-semaphorin receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:PLXNA1			KEGG-&-1&-hsa04360-&&-Axon guidance	PLXNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLXNA1	0.35046935	0.03809524	17	5	FALSE	PLXNA1	PLXNA1	93	0	16	0	0.69111391	FALSE	1	PLXNA1	29616	0.08337842
787747	taxon:9606	2.85961872	4.61E-06	178844	1902	POU class 1 homeobox 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051169-&&-nuclear transport-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0032962-&&-positive regulation of inositol trisphosphate biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0008340-&&-determination of adult lifespan-%%-GO:0060133-&&-somatotropin secreting cell development-%%-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001708-&&-cell fate specification-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:POU1F1				POU1F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU1F1	0.34969697	0.24264706	17	4	FALSE	POU1F1	POU1F1	132.7647059	0	17	0	0.69006355	FALSE	0	POU1F1	10742	0.11832861
787750	taxon:9606	2.77658736	4.20E-06	178841	1902	POU class 2 homeobox 2	gene	biological_process-&-1&-GO:0006959-&&-humoral immune response-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0048469-&&-cell maturation-%%-GO:0002335-&&-mature B cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0002380-&&-immunoglobulin secretion involved in immune response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:POU2F2				POU2F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU2F2	0.36015434	0.23809524	17	4	FALSE	POU2F2	POU2F2	162.7333333	0	16	0	0.70390211	FALSE	1	POU2F2	8326	0.10521777
787845	taxon:9606	2.76477076	1.92E-05	178724	1902	THAP domain containing 12	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006950-&&-response to stress-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:THAP12				THAP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THAP12	0.36169364	0.06666667	17	4	FALSE	THAP12	THAP12	146.5333333	0	16	0	0.70587154	FALSE	1	THAP12	20906	0.09005343
787992	taxon:9606	2.87442886	1.47E-05	178443	1902	platelet derived growth factor subunit A	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009611-&&-response to wounding-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0001775-&&-cell activation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0001942-&&-hair follicle development-%%-GO:0072124-&&-regulation of glomerular mesangial cell proliferation-%%-GO:1990401-&&-embryonic lung development-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048286-&&-lung alveolus development-%%-GO:0060683-&&-regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:2000278-&&-regulation of DNA biosynthetic process-%%-GO:0043588-&&-skin development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0010512-&&-negative regulation of phosphatidylinositol biosynthetic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0035793-&&-positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0002576-&&-platelet degranulation-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0042060-&&-wound healing-%%-GO:0030031-&&-cell projection assembly-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0014910-&&-regulation of smooth muscle cell migration-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0050919-&&-negative chemotaxis|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005902-&&-microvillus-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:PDGFA			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04540-&&-Gap junction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton	PDGFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFA	0.3478952	0.22857143	17	5	FALSE	PDGFA	PDGFA	83.93333333	0	16	0	0.68759519	FALSE	1	PDGFA	16226	0.08151751
788014	taxon:9606	2.71892233	5.00E-07	178393	1902	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	gene	biological_process-&-1&-GO:0006003-&&-fructose 2,6-bisphosphate metabolic process-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0007420-&&-brain development-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003873-&&-6-phosphofructo-2-kinase activity-%%-GO:0004331-&&-fructose-2,6-bisphosphate 2-phosphatase activity	G:9606:PFKFB3			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway	PFKFB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKFB3	0.36779278	0.52941176	17	4	FALSE	PFKFB3	PFKFB3	369	0	17	0	0.71351295	FALSE	0	PFKFB3	4604	0.19655896
788096	taxon:9606	2.61887506	1.49E-05	178245	1902	ATP binding cassette subfamily B member 1	gene	biological_process-&-1&-GO:0045332-&&-phospholipid translocation-%%-GO:0055085-&&-transmembrane transport-%%-GO:0042908-&&-xenobiotic transport-%%-GO:0099040-&&-ceramide translocation-%%-GO:0072089-&&-stem cell proliferation-%%-GO:0006810-&&-transport-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0042493-&&-response to drug-%%-GO:0006855-&&-drug transmembrane transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0099038-&&-ceramide-translocating ATPase activity-%%-GO:0090555-&&-phosphatidylethanolamine-translocating ATPase activity-%%-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0008559-&&-xenobiotic-transporting ATPase activity-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0090554-&&-phosphatidylcholine-translocating ATPase activity	G:9606:ABCB1			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer-%%-hsa02010-&&-ABC transporters-%%-hsa04976-&&-Bile secretion-%%-hsa05226-&&-Gastric cancer	ABCB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCB1	0.38184334	0.08088235	17	4	FALSE	ABCB1	ABCB1	239.8823529	0	17	0	0.73018749	FALSE	0	ABCB1	26928	0.09705406
788102	taxon:9606	2.70521506	1.57E-05	178236	1902	phosphorylase kinase regulatory subunit alpha 2	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005964-&&-phosphorylase kinase complex|molecular_function-&-1&-GO:0004689-&&-phosphorylase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:PHKA2			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04020-&&-Calcium signaling pathway	PHKA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHKA2	0.36965638	0.11029412	17	4	FALSE	PHKA2	PHKA2	155.1176471	0	17	0	0.71579749	FALSE	0	PHKA2	24014	0.08014744
788104	taxon:9606	2.6135182	1.88E-05	178235	1902	phosphorylase kinase regulatory subunit beta	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005964-&&-phosphorylase kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004689-&&-phosphorylase kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:PHKB			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04020-&&-Calcium signaling pathway	PHKB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHKB	0.38262599	0.14705882	17	4	FALSE	PHKB	PHKB	209.9411765	0	17	0	0.7310803	FALSE	0	PHKB	30642	0.0829342
788110	taxon:9606	2.76004412	1.31E-05	178217	1902	protein tyrosine phosphatase, non-receptor type 4	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PTPN4				PTPN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN4	0.36231305	0.18382353	17	4	FALSE	PTPN4	PTPN4	165.5882353	0	17	0	0.70665931	FALSE	0	PTPN4	19526	0.10370644
788117	taxon:9606	2.7364109	5.86E-05	178209	1902	protein tyrosine phosphatase, receptor type A	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRA				PTPRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRA	0.36544219	0.17142857	17	5	FALSE	PTPRA	PTPRA	171.6	0	16	0	0.71059818	FALSE	1	PTPRA	58392	0.09835438
788254	taxon:9606	2.73515046	2.42E-05	177999	1902	regulator of G-protein signaling 7	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006457-&&-protein folding-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS7				RGS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS7	0.3656106	0.08088235	17	4	FALSE	RGS7	RGS7	157.3529412	0	17	0	0.71080826	FALSE	0	RGS7	31850	0.08830146
788333	taxon:9606	2.61146999	7.85E-05	177867	1902	serpin family B member 4	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030162-&&-regulation of proteolysis-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0042270-&&-protection from natural killer cell mediated cytotoxicity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding-%%-GO:0019899-&&-enzyme binding	G:9606:SERPINB4			KEGG-&-1&-hsa05146-&&-Amoebiasis	SERPINB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB4	0.38292609	0.125	17	4	FALSE	SERPINB4	SERPINB4	232.8823529	0	17	0	0.73142167	FALSE	0	SERPINB4	88804	0.09283602
788334	taxon:9606	2.56640933	3.39E-05	177866	1902	stearoyl-CoA desaturase	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006636-&&-unsaturated fatty acid biosynthetic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004768-&&-stearoyl-CoA 9-desaturase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0005506-&&-iron ion binding	G:9606:SCD			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids	SCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCD	0.38964946	0.19852941	17	4	FALSE	SCD	SCD	260.5294118	0	17	0	0.73893178	FALSE	0	SCD	45432	0.09337102
788343	taxon:9606	3.0762565	8.07E-05	177836	1902	C-C motif chemokine ligand 7	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:2000503-&&-positive regulation of natural killer cell chemotaxis-%%-GO:0006935-&&-chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway|cellular_component-&-1&-GO:0005623-&&-cell-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0031726-&&-CCR1 chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0008201-&&-heparin binding	G:9606:CCL7			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL7	0.32507042	0.01904762	17	4	FALSE	CCL7	CCL7	31.26666667	0	16	0	0.65395725	FALSE	1	CCL7	73136	0.08388278
788449	taxon:9606	2.86686624	1.32E-05	177649	1902	solute carrier family 4 member 1 (Diego blood group)	gene	biological_process-&-1&-GO:0006820-&&-anion transport-%%-GO:0006873-&&-cellular ion homeostasis-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0006821-&&-chloride transport-%%-GO:1902476-&&-chloride transmembrane transport|cellular_component-&-1&-GO:0030863-&&-cortical cytoskeleton-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0005452-&&-inorganic anion exchanger activity-%%-GO:0005515-&&-protein binding-%%-GO:0008509-&&-anion transmembrane transporter activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0015106-&&-bicarbonate transmembrane transporter activity-%%-GO:0030506-&&-ankyrin binding-%%-GO:0015301-&&-anion:anion antiporter activity-%%-GO:0043495-&&-protein anchor-%%-GO:0015108-&&-chloride transmembrane transporter activity	G:9606:SLC4A1			KEGG-&-1&-hsa04966-&&-Collecting duct acid secretion	SLC4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC4A1	0.34881293	0.08571429	17	4	FALSE	SLC4A1	SLC4A1	85.6	0	16	0	0.68885563	FALSE	1	SLC4A1	14242	0.09020437
788546	taxon:9606	2.64282338	8.95E-06	177460	1902	spermidine synthase	gene	biological_process-&-1&-GO:0008295-&&-spermidine biosynthetic process-%%-GO:0006595-&&-polyamine metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004766-&&-spermidine synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SRM			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways	SRM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRM	0.37838321	0.0952381	17	4	FALSE	SRM	SRM	301	0	16	0	0.7261961	FALSE	1	SRM	23222	0.12821606
788615	taxon:9606	2.85315897	4.72E-06	177301	1902	TEA domain transcription factor 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048568-&&-embryonic organ development-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0035329-&&-hippo signaling|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0000982-&&-transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001159-&&-core promoter proximal region DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TEAD1			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	TEAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEAD1	0.35048871	0.0952381	17	4	FALSE	TEAD1	TEAD1	97.26666667	0	16	0	0.69114017	FALSE	1	TEAD1	8232	0.08919583
788653	taxon:9606	2.80652277	5.64E-05	177250	1902	transforming growth factor alpha	gene	biological_process-&-1&-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0051781-&&-positive regulation of cell division|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:TGFA	TGFA	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05212-&&-Pancreatic cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma	TGFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFA	0.35631281	0.03809524	17	4	FALSE	TGFA	TGFA	110	0	16	0	0.69891287	FALSE	1	TGFA	42270	0.08046146
788661	taxon:9606	2.62265637	6.82E-05	177238	1902	transglutaminase 1	gene	biological_process-&-1&-GO:0018149-&&-peptide cross-linking-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:0043163-&&-cell envelope organization-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0070268-&&-cornification-%%-GO:0030216-&&-keratinocyte differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001533-&&-cornified envelope-%%-GO:0005886-&&-plasma membrane-%%-GO:0031224-&&-intrinsic component of membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0003810-&&-protein-glutamine gamma-glutamyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:TGM1				TGM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGM1	0.3812928	0.05147059	17	4	FALSE	TGM1	TGM1	226.5294118	0	17	0	0.72955727	FALSE	0	TGM1	62572	0.09137382
788698	taxon:9606	2.90593981	2.18E-05	177163	1902	troponin I3, cardiac type	gene	biological_process-&-1&-GO:0003009-&&-skeletal muscle contraction-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060047-&&-heart contraction-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007507-&&-heart development-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0001570-&&-vasculogenesis-%%-GO:0001980-&&-regulation of systemic arterial blood pressure by ischemic conditions-%%-GO:0032780-&&-negative regulation of ATPase activity-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0005861-&&-troponin complex-%%-GO:0030017-&&-sarcomere-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0003779-&&-actin binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0031014-&&-troponin T binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0030172-&&-troponin C binding	G:9606:TNNI3			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TNNI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNNI3	0.34412275	0.11428571	17	5	FALSE	TNNI3	TNNI3	71.2	0	16	0	0.68234336	FALSE	1	TNNI3	17292	0.08556494
789016	taxon:9606	2.72175831	2.10E-05	176373	1902	McKusick-Kaufman syndrome	gene	biological_process-&-1&-GO:0007368-&&-determination of left/right symmetry-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0060296-&&-regulation of cilium beat frequency involved in ciliary motility-%%-GO:0006457-&&-protein folding-%%-GO:0007286-&&-spermatid development-%%-GO:0001947-&&-heart looping-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0042311-&&-vasodilation-%%-GO:0032402-&&-melanosome transport-%%-GO:0060027-&&-convergent extension involved in gastrulation-%%-GO:0008406-&&-gonad development-%%-GO:0060271-&&-cilium assembly-%%-GO:0051492-&&-regulation of stress fiber assembly-%%-GO:0051877-&&-pigment granule aggregation in cell center-%%-GO:0051216-&&-cartilage development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0038108-&&-negative regulation of appetite by leptin-mediated signaling pathway-%%-GO:0035176-&&-social behavior-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0046907-&&-intracellular transport-%%-GO:0060324-&&-face development-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0014824-&&-artery smooth muscle contraction-%%-GO:0006458-&&-'de novo' protein folding-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0021756-&&-striatum development-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0007507-&&-heart development-%%-GO:0021766-&&-hippocampus development-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0045494-&&-photoreceptor cell maintenance-%%-GO:0007601-&&-visual perception|cellular_component-&-1&-GO:1902636-&&-kinociliary basal body-%%-GO:0005813-&&-centrosome-%%-GO:0031514-&&-motile cilium-%%-GO:0005622-&&-intracellular-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0044183-&&-protein binding involved in protein folding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding	G:9606:MKKS				MKKS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKKS	0.36740955	0.25735294	17	4	FALSE	MKKS	MKKS	181.2352941	0	17	0	0.71304028	FALSE	0	MKKS	25998	0.09905767
789113	taxon:9606	2.69276824	1.56E-05	176174	1902	timeless circadian clock	gene	biological_process-&-1&-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0072719-&&-cellular response to cisplatin-%%-GO:0006260-&&-DNA replication-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0044770-&&-cell cycle phase transition-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0009582-&&-detection of abiotic stimulus-%%-GO:0051301-&&-cell division-%%-GO:0072711-&&-cellular response to hydroxyurea-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0009628-&&-response to abiotic stimulus-%%-GO:1904976-&&-cellular response to bleomycin-%%-GO:2000781-&&-positive regulation of double-strand break repair-%%-GO:0007623-&&-circadian rhythm-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0030324-&&-lung development|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:TIMELESS				TIMELESS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMELESS	0.37136505	0.15441176	17	4	FALSE	TIMELESS	TIMELESS	168.9411765	0	17	0	0.71787196	FALSE	0	TIMELESS	24122	0.08229555
789134	taxon:9606	2.72695762	1.14E-05	176139	1902	ribosomal protein S6 kinase A4	gene	biological_process-&-1&-GO:0043988-&&-histone H3-S28 phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0033129-&&-positive regulation of histone phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006954-&&-inflammatory response-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043987-&&-histone H3-S10 phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0035066-&&-positive regulation of histone acetylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0048273-&&-mitogen-activated protein kinase p38 binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004711-&&-ribosomal protein S6 kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0000287-&&-magnesium ion binding	G:9606:RPS6KA4			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04010-&&-MAPK signaling pathway	RPS6KA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KA4	0.36670904	0.1047619	17	4	FALSE	RPS6KA4	RPS6KA4	179.9333333	0	16	0	0.71217373	FALSE	1	RPS6KA4	20418	0.09607843
789172	taxon:9606	2.96281708	5.87E-06	159665	1902	keratin associated protein 26-1	gene	biological_process-&-1&-GO:0031424-&&-keratinization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KRTAP26-1				KRTAP26-1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRTAP26-1	0.33751662	0.38095238	17	5	FALSE	KRTAP26-1	KRTAP26-1	80.53333333	0	16	0	0.67286382	FALSE	1	KRTAP26-1	9754	0.12017937
789231	taxon:9606	2.7378289	1.02E-05	175959	1902	aldo-keto reductase family 7 member A2	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0044598-&&-doxorubicin metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0019119-&&-phenanthrene-9,10-epoxide hydrolase activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0005515-&&-protein binding	G:9606:AKR7A2			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450	AKR7A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR7A2	0.36525292	0.13333333	17	4	FALSE	AKR7A2	AKR7A2	208.3333333	0	16	0	0.71036185	FALSE	1	AKR7A2	15282	0.11699457
789445	taxon:9606	2.66866236	2.58E-05	175445	1902	secretory carrier membrane protein 1	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0006892-&&-post-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0042589-&&-zymogen granule membrane-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SCAMP1				SCAMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAMP1	0.37471957	0.0952381	17	4	FALSE	SCAMP1	SCAMP1	189.2	0	16	0	0.72188961	FALSE	1	SCAMP1	36540	0.08658723
789482	taxon:9606	2.86056405	9.95E-06	175365	1902	apoptosis associated tyrosine kinase	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:AATK				AATK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AATK	0.34958141	0.01470588	17	4	FALSE	AATK	AATK	92.05882353	0	17	0	0.68990599	FALSE	0	AATK	14222	0.08736279
789563	taxon:9606	2.64959824	1.99E-05	175169	1902	C2 calcium dependent domain containing 5	gene	biological_process-&-1&-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0038028-&&-insulin receptor signaling pathway via phosphatidylinositol 3-kinase-%%-GO:0006906-&&-vesicle fusion-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0010828-&&-positive regulation of glucose transport-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0065002-&&-intracellular protein transmembrane transport-%%-GO:0031340-&&-positive regulation of vesicle fusion|cellular_component-&-1&-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0005829-&&-cytosol-%%-GO:0032587-&&-ruffle membrane-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding	G:9606:C2CD5				C2CD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C2CD5	0.37741571	0.13970588	17	4	FALSE	C2CD5	C2CD5	204.7647059	0	17	0	0.72506696	FALSE	0	C2CD5	35656	0.08851541
789665	taxon:9606	2.61052466	3.44E-05	174946	1902	CDP-diacylglycerol--inositol 3-phosphatidyltransferase	gene	biological_process-&-1&-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0046341-&&-CDP-diacylglycerol metabolic process|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019992-&&-diacylglycerol binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0043178-&&-alcohol binding-%%-GO:0003881-&&-CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:CDIPT			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	CDIPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDIPT	0.38306476	0.05882353	17	5	FALSE	CDIPT	CDIPT	223.4705882	0	17	0	0.73157922	FALSE	0	CDIPT	46394	0.08859754
789668	taxon:9606	2.77469671	7.51E-06	174938	1902	lysophospholipase I	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:0002084-&&-protein depalmitoylation-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0042997-&&-negative regulation of Golgi to plasma membrane protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004622-&&-lysophospholipase activity-%%-GO:0008474-&&-palmitoyl-(protein) hydrolase activity-%%-GO:0016298-&&-lipase activity	G:9606:LYPLA1			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa00564-&&-Glycerophospholipid metabolism	LYPLA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYPLA1	0.36039975	0.20952381	17	4	FALSE	LYPLA1	LYPLA1	200.8	0	16	0	0.70421722	FALSE	1	LYPLA1	12652	0.12929553
789732	taxon:9606	2.84985032	2.62E-05	174807	1902	FRAT1, WNT signaling pathway regulator	gene	biological_process-&-1&-GO:1904886-&&-beta-catenin destruction complex disassembly|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FRAT1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	FRAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FRAT1	0.35089562	0.04411765	17	5	FALSE	FRAT1	FRAT1	86.35294118	0	17	0	0.69169161	FALSE	0	FRAT1	23136	0.0790086
789989	taxon:9606	2.75925634	1.70E-05	174182	1902	metal response element binding transcription factor 2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061087-&&-positive regulation of histone H3-K27 methylation-%%-GO:0061086-&&-negative regulation of histone H3-K27 methylation-%%-GO:0007379-&&-segment specification-%%-GO:0019827-&&-stem cell population maintenance|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035098-&&-ESC/E(Z) complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0035064-&&-methylated histone binding	G:9606:MTF2				MTF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTF2	0.36241649	0.125	17	5	FALSE	MTF2	MTF2	153.1764706	0	17	0	0.70679061	FALSE	0	MTF2	24268	0.09303575
790135	taxon:9606	2.81298251	2.68E-05	173795	1902	CD93 molecule	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0006909-&&-phagocytosis-%%-GO:0042116-&&-macrophage activation-%%-GO:0016032-&&-viral process-%%-GO:0016337-&&-single organismal cell-cell adhesion|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0004872-&&-receptor activity-%%-GO:0001849-&&-complement component C1q binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:CD93				CD93	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD93	0.35549457	0.02941176	17	4	FALSE	CD93	CD93	92.41176471	0	17	0	0.69783625	FALSE	0	CD93	26284	0.07106137
790191	taxon:9606	2.69954309	8.42E-06	173683	1902	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:HECW1				HECW1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HECW1	0.37043306	0.20952381	17	4	FALSE	HECW1	HECW1	208.9333333	0	16	0	0.71674282	FALSE	1	HECW1	17522	0.1039323
790334	taxon:9606	2.52434221	5.79E-06	173299	1902	family with sequence similarity 98 member A	gene	cellular_component-&-1&-GO:0072669-&&-tRNA-splicing ligase complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:FAM98A				FAM98A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM98A	0.3961428	0.49264706	17	4	FALSE	FAM98A	FAM98A	466.4705882	0	17	0	0.74594297	FALSE	0	FAM98A	14374	0.1526409
790343	taxon:9606	2.73278714	1.93E-05	173272	1902	AAR2 splicing factor homolog	gene	biological_process-&-1&-GO:0000244-&&-spliceosomal tri-snRNP complex assembly	G:9606:AAR2				AAR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AAR2	0.36592678	0.14705882	17	4	FALSE	AAR2	AAR2	153.2941177	0	17	0	0.71120214	FALSE	0	AAR2	23016	0.08504725
790387	taxon:9606	2.69780999	9.85E-06	173151	1902	makorin ring finger protein 1	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:MKRN1				MKRN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKRN1	0.37067103	0.13970588	17	4	FALSE	MKRN1	MKRN1	184.7647059	0	17	0	0.71703167	FALSE	0	MKRN1	16598	0.09229412
790424	taxon:9606	2.70899638	1.40E-05	173034	1902	interferon induced protein with tetratricopeptide repeats 5	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0032587-&&-ruffle membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0000049-&&-tRNA binding-%%-GO:0003727-&&-single-stranded RNA binding	G:9606:IFIT5				IFIT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFIT5	0.3691404	0.29411765	17	4	FALSE	IFIT5	IFIT5	153.5294118	0	17	0	0.71516727	FALSE	0	IFIT5	23886	0.07955966
790501	taxon:9606	2.73436269	1.31E-05	172670	1902	kelch like family member 3	gene	biological_process-&-1&-GO:0050801-&&-ion homeostasis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0072156-&&-distal tubule morphogenesis-%%-GO:0070294-&&-renal sodium ion absorption|cellular_component-&-1&-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL3				KLHL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL3	0.36571593	0.15238095	17	4	FALSE	KLHL3	KLHL3	159.2666667	0	16	0	0.71093955	FALSE	1	KLHL3	19502	0.08942542
790603	taxon:9606	2.81156452	1.27E-05	171797	1902	nuclear receptor binding factor 2	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0043550-&&-regulation of lipid kinase activity-%%-GO:0010506-&&-regulation of autophagy-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005776-&&-autophagosome-%%-GO:0035032-&&-phosphatidylinositol 3-kinase complex, class III-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NRBF2			KEGG-&-1&-hsa04140-&&-Autophagy - animal	NRBF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRBF2	0.35567386	0.08823529	17	4	FALSE	NRBF2	NRBF2	112.4117647	0	17	0	0.69807258	FALSE	0	NRBF2	17626	0.08330424
790630	taxon:9606	2.70458484	1.42E-05	171710	1902	MAGE family member C2	gene	biological_process-&-1&-GO:0044257-&&-cellular protein catabolic process-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:MAGEC2				MAGEC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEC2	0.36974251	0.125	17	4	FALSE	MAGEC2	MAGEC2	180	0	17	0	0.71590253	FALSE	0	MAGEC2	22070	0.09007814
790631	taxon:9606	2.61383331	2.63E-05	171705	1902	ring finger protein 138	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0010792-&&-DNA double-strand break processing involved in repair via single-strand annealing-%%-GO:0016055-&&-Wnt signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:RNF138				RNF138	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF138	0.38257987	0.08823529	17	4	FALSE	RNF138	RNF138	210.2941177	0	17	0	0.73102778	FALSE	0	RNF138	38076	0.08381238
790809	taxon:9606	2.67575232	7.96E-06	171137	1902	suppressor of cytokine signaling 7	gene	biological_process-&-1&-GO:0021942-&&-radial glia guided migration of Purkinje cell-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0040008-&&-regulation of growth-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0008150-&&-biological_process-%%-GO:0021819-&&-layer formation in cerebral cortex|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005515-&&-protein binding	G:9606:SOCS7			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS7	0.37372667	0.29411765	17	5	FALSE	SOCS7	SOCS7	207.2941177	0	17	0	0.72070795	FALSE	0	SOCS7	15006	0.0981879
790816	taxon:9606	2.69119269	7.25E-06	171120	1902	ribonucleotide reductase regulatory TP53 inducible subunit M2B	gene	biological_process-&-1&-GO:0003014-&&-renal system process-%%-GO:0014075-&&-response to amine-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:1902254-&&-negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006264-&&-mitochondrial DNA replication-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0006281-&&-DNA repair-%%-GO:0009200-&&-deoxyribonucleoside triphosphate metabolic process-%%-GO:0009263-&&-deoxyribonucleotide biosynthetic process-%%-GO:0001822-&&-kidney development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004748-&&-ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	G:9606:RRM2B			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	RRM2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRM2B	0.37158246	0.2	17	4	FALSE	RRM2B	RRM2B	215.2	0	16	0	0.71813455	FALSE	1	RRM2B	14198	0.10381458
790828	taxon:9606	2.8457539	1.96E-05	171054	1902	F11 receptor	gene	biological_process-&-1&-GO:0031032-&&-actomyosin structure organization-%%-GO:0090559-&&-regulation of membrane permeability-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0050892-&&-intestinal absorption-%%-GO:0070830-&&-bicellular tight junction assembly-%%-GO:0009314-&&-response to radiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0006954-&&-inflammatory response-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0070062-&&-extracellular exosome-%%-GO:0036057-&&-slit diaphragm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:F11R			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04530-&&-Tight junction-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	F11R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F11R	0.35140073	0.08571429	17	4	FALSE	F11R	F11R	95.26666667	0	16	0	0.69237435	FALSE	1	F11R	18116	0.08230524
790836	taxon:9606	2.66393572	3.75E-05	171007	1902	activating signal cointegrator 1 complex subunit 1	gene	biological_process-&-1&-GO:0006307-&&-DNA dealkylation involved in DNA repair-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:ASCC1				ASCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASCC1	0.37538443	0.11764706	17	4	FALSE	ASCC1	ASCC1	187.8823529	0	17	0	0.72267738	FALSE	0	ASCC1	40922	0.08561763
791006	taxon:9606	3.00110288	1.28E-05	170430	1902	syntaxin 18	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:1902117-&&-positive regulation of organelle assembly-%%-GO:0090158-&&-endoplasmic reticulum membrane organization-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:1902953-&&-positive regulation of ER to Golgi vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031201-&&-SNARE complex|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding	G:9606:STX18			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport-%%-hsa04145-&&-Phagosome	STX18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STX18	0.33321084	0.19852941	17	5	FALSE	STX18	STX18	42.82352941	0	17	0	0.66648285	FALSE	0	STX18	9464	0.07667124
791107	taxon:9606	2.73168426	5.83E-05	170023	1902	synaptojanin 2 binding protein	gene	biological_process-&-1&-GO:0008593-&&-regulation of Notch signaling pathway-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:1903671-&&-negative regulation of sprouting angiogenesis-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006605-&&-protein targeting-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0048312-&&-intracellular distribution of mitochondria-%%-GO:0007266-&&-Rho protein signal transduction|cellular_component-&-1&-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:SYNJ2BP				SYNJ2BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNJ2BP	0.36607452	0.05147059	17	4	FALSE	SYNJ2BP	SYNJ2BP	129.6470588	0	17	0	0.71138596	FALSE	0	SYNJ2BP	45478	0.07194998
791210	taxon:9606	2.62990389	1.67E-05	169721	1902	ER membrane protein complex subunit 3	gene	biological_process-&-1&-GO:0034975-&&-protein folding in endoplasmic reticulum-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0072546-&&-ER membrane protein complex|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:EMC3				EMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EMC3	0.38024203	0.11764706	17	4	FALSE	EMC3	EMC3	239.5294118	0	17	0	0.72834935	FALSE	0	EMC3	40966	0.09921747
791241	taxon:9606	2.8391366	1.34E-05	169548	1902	transient receptor potential cation channel subfamily V member 5	gene	biological_process-&-1&-GO:0006816-&&-calcium ion transport-%%-GO:0051262-&&-protein tetramerization-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0035809-&&-regulation of urine volume-%%-GO:1990035-&&-calcium ion import into cell|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:TRPV5			KEGG-&-1&-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	TRPV5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPV5	0.35221976	0.03676471	17	4	FALSE	TRPV5	TRPV5	89.29411765	0	17	0	0.69347723	FALSE	0	TRPV5	15464	0.07588185
791257	taxon:9606	2.80289901	2.10E-05	169485	1902	GRIP1 associated protein 1	gene	biological_process-&-1&-GO:1905244-&&-regulation of modification of synaptic structure-%%-GO:0098887-&&-neurotransmitter receptor transport, endosome to postsynaptic membrane-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0098837-&&-postsynaptic recycling endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:GRIPAP1				GRIPAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIPAP1	0.35677347	0.05714286	17	4	FALSE	GRIPAP1	GRIPAP1	119.6	0	16	0	0.69951683	FALSE	1	GRIPAP1	23854	0.08612717
791314	taxon:9606	2.7479124	1.17E-05	169216	1902	coenzyme Q8A	gene	biological_process-&-1&-GO:0006744-&&-ubiquinone biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0043531-&&-ADP binding-%%-GO:0016301-&&-kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:COQ8A				COQ8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COQ8A	0.36391262	0.23809524	17	4	FALSE	COQ8A	COQ8A	156.6666667	0	16	0	0.70868127	FALSE	1	COQ8A	21180	0.09153996
791336	taxon:9606	2.59792028	1.51E-05	169104	1902	KIAA1191	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:KIAA1191				KIAA1191	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA1191	0.38492328	0.10294118	17	4	FALSE	KIAA1191	KIAA1191	228.2941177	0	17	0	0.73367995	FALSE	0	KIAA1191	27584	0.0874349
791365	taxon:9606	2.60501024	1.20E-05	168961	1902	ring finger protein 213	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2000051-&&-negative regulation of non-canonical Wnt signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RNF213				RNF213	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF213	0.38387565	0.05714286	17	4	FALSE	RNF213	RNF213	252.5333333	0	16	0	0.73249829	FALSE	1	RNF213	25820	0.09859155
791413	taxon:9606	2.5703482	5.40E-06	168740	1902	YTH domain containing 2	gene	biological_process-&-1&-GO:0070555-&&-response to interleukin-1-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0044829-&&-positive regulation by host of viral genome replication-%%-GO:0006396-&&-RNA processing|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0070063-&&-RNA polymerase binding-%%-GO:1990247-&&-N6-methyladenosine-containing RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008186-&&-RNA-dependent ATPase activity	G:9606:YTHDC2				YTHDC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YTHDC2	0.38905235	0.30882353	17	4	FALSE	YTHDC2	YTHDC2	404.8235294	0	17	0	0.7382753	FALSE	0	YTHDC2	14338	0.14570364
791453	taxon:9606	2.83125886	6.48E-06	168583	1902	chromosome 7 open reading frame 25	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C7orf25				C7orf25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C7orf25	0.35319978	0.01904762	17	5	FALSE	C7orf25	C7orf25	102.9333333	0	16	0	0.69479019	FALSE	1	C7orf25	10522	0.08439306
791521	taxon:9606	2.71435324	4.23E-05	168267	1902	polypeptide N-acetylgalactosaminyltransferase 12	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004653-&&-polypeptide N-acetylgalactosaminyltransferase activity	G:9606:GALNT12			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00512-&&-Mucin type O-glycan biosynthesis	GALNT12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GALNT12	0.36841189	0.04411765	17	5	FALSE	GALNT12	GALNT12	155.4117647	0	17	0	0.71427446	FALSE	0	GALNT12	39924	0.08112103
791529	taxon:9606	2.72711517	1.48E-05	168238	1902	golgi reassembly stacking protein 1	gene	biological_process-&-1&-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0015031-&&-protein transport-%%-GO:0007030-&&-Golgi organization-%%-GO:0050774-&&-negative regulation of dendrite morphogenesis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GORASP1	GORASP1	TRUE		GORASP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GORASP1	0.36668785	0.11428571	17	4	FALSE	GORASP1	GORASP1	170.8	0	16	0	0.71214747	FALSE	1	GORASP1	19584	0.09196765
791571	taxon:9606	2.62628013	6.57E-06	167963	1902	zinc finger CCCH-type containing 12A	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:1903799-&&-negative regulation of production of miRNAs involved in gene silencing by miRNA-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:1902714-&&-negative regulation of interferon-gamma secretion-%%-GO:1904637-&&-cellular response to ionomycin-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:1903936-&&-cellular response to sodium arsenite-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:1900016-&&-negative regulation of cytokine production involved in inflammatory response-%%-GO:1900165-&&-negative regulation of interleukin-6 secretion-%%-GO:0006954-&&-inflammatory response-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0050713-&&-negative regulation of interleukin-1 beta secretion-%%-GO:0030154-&&-cell differentiation-%%-GO:0055118-&&-negative regulation of cardiac muscle contraction-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0098586-&&-cellular response to virus-%%-GO:0044828-&&-negative regulation by host of viral genome replication-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0016579-&&-protein deubiquitination-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0090501-&&-RNA phosphodiester bond hydrolysis-%%-GO:0007399-&&-nervous system development-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0001525-&&-angiogenesis-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051259-&&-protein oligomerization-%%-GO:0061014-&&-positive regulation of mRNA catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0000294-&&-nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay-%%-GO:2000627-&&-positive regulation of miRNA catabolic process-%%-GO:0051607-&&-defense response to virus-%%-GO:1903003-&&-positive regulation of protein deubiquitination-%%-GO:0010656-&&-negative regulation of muscle cell apoptotic process-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0042307-&&-positive regulation of protein import into nucleus-%%-GO:0043031-&&-negative regulation of macrophage activation-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1904468-&&-negative regulation of tumor necrosis factor secretion-%%-GO:0010468-&&-regulation of gene expression-%%-GO:1990869-&&-cellular response to chemokine|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0042406-&&-extrinsic component of endoplasmic reticulum membrane-%%-GO:0030867-&&-rough endoplasmic reticulum membrane-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0035198-&&-miRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0035613-&&-RNA stem-loop binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003730-&&-mRNA 3'-UTR binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003677-&&-DNA binding-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0004532-&&-exoribonuclease activity-%%-GO:0004540-&&-ribonuclease activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0043022-&&-ribosome binding	G:9606:ZC3H12A				ZC3H12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZC3H12A	0.38076669	0.28571429	17	4	FALSE	ZC3H12A	ZC3H12A	265.5333333	0	16	0	0.72895331	FALSE	1	ZC3H12A	14556	0.10983313
791575	taxon:9606	2.65763353	1.44E-05	167948	1902	splA/ryanodine receptor domain and SOCS box containing 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:SPSB1				SPSB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPSB1	0.3762746	0.15441176	17	4	FALSE	SPSB1	SPSB1	203.7647059	0	17	0	0.72372775	FALSE	0	SPSB1	36408	0.09063064
791580	taxon:9606	2.64865291	1.77E-05	167939	1902	ring finger protein 34	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0035872-&&-nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway-%%-GO:2000374-&&-regulation of oxygen metabolic process-%%-GO:1901797-&&-negative regulation of signal transduction by p53 class mediator-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0070417-&&-cellular response to cold-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2001271-&&-negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:1901981-&&-phosphatidylinositol phosphate binding	G:9606:RNF34				RNF34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF34	0.37755041	0.13235294	17	4	FALSE	RNF34	RNF34	186.7058824	0	17	0	0.72522452	FALSE	0	RNF34	30446	0.08157069
791654	taxon:9606	2.98960139	1.33E-05	167565	1902	unc-93 homolog B1 (C. elegans)	gene	biological_process-&-1&-GO:0034154-&&-toll-like receptor 7 signaling pathway-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0045087-&&-innate immune response-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0034162-&&-toll-like receptor 9 signaling pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0034138-&&-toll-like receptor 3 signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005764-&&-lysosome-%%-GO:0032009-&&-early phagosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005768-&&-endosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0035325-&&-Toll-like receptor binding	G:9606:UNC93B1				UNC93B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC93B1	0.33449275	0.10294118	17	5	FALSE	UNC93B1	UNC93B1	47.47058824	0	17	0	0.66839977	FALSE	0	UNC93B1	14922	0.08500265
791660	taxon:9606	2.77501182	2.38E-05	167559	1902	testis specific serine kinase 3	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:TSSK3				TSSK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSSK3	0.36035883	0.03676471	17	5	FALSE	TSSK3	TSSK3	117.6470588	0	17	0	0.7041647	FALSE	0	TSSK3	28196	0.07630953
791672	taxon:9606	2.69387112	2.34E-05	167490	1902	kelch like family member 15	gene	biological_process-&-1&-GO:0071630-&&-ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome-%%-GO:2000042-&&-negative regulation of double-strand break repair via homologous recombination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL15				KLHL15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL15	0.37121301	0.32380952	17	4	FALSE	KLHL15	KLHL15	253.9333333	0	16	0	0.71768815	FALSE	1	KLHL15	20738	0.12428991
791675	taxon:9606	2.88608792	1.17E-05	167483	1902	G kinase anchoring protein 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:GKAP1				GKAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GKAP1	0.34648979	0.07619048	17	4	FALSE	GKAP1	GKAP1	75.8	0	16	0	0.68565201	FALSE	1	GKAP1	11596	0.0832047
791686	taxon:9606	2.79218528	6.29E-06	167433	1902	proline rich 3	gene	molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PRR3				PRR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRR3	0.35814242	0.08823529	17	5	FALSE	PRR3	PRR3	137.9411765	0	17	0	0.70130245	FALSE	0	PRR3	11480	0.09476673
791690	taxon:9606	2.82259335	4.76E-05	167411	1902	collagen type XVIII alpha 1 chain	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0001525-&&-angiogenesis-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0007601-&&-visual perception-%%-GO:0051599-&&-response to hydrostatic pressure|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005198-&&-structural molecule activity	G:9606:COL18A1			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	COL18A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL18A1	0.35428412	0.03676471	17	4	FALSE	COL18A1	COL18A1	98.41176471	0	17	0	0.69623444	FALSE	0	COL18A1	41848	0.07873085
791729	taxon:9606	2.81140696	2.11E-05	167152	1902	family with sequence similarity 110 member A	gene	cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM110A				FAM110A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM110A	0.35569379	0.07352941	17	4	FALSE	FAM110A	FAM110A	130.5882353	0	17	0	0.69809884	FALSE	0	FAM110A	26152	0.09843938
791736	taxon:9606	2.71781944	1.12E-05	167124	1902	family with sequence similarity 103 member A1	gene	biological_process-&-1&-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0032259-&&-methylation-%%-GO:0036031-&&-recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005845-&&-mRNA cap binding complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:FAM103A1				FAM103A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM103A1	0.36794203	0.13235294	17	4	FALSE	FAM103A1	FAM103A1	220.7647059	0	17	0	0.71369676	FALSE	0	FAM103A1	22028	0.11689851
791875	taxon:9606	2.63478809	2.16E-05	182944	1902	alcohol dehydrogenase 5 (class III), chi polypeptide	gene	biological_process-&-1&-GO:0018119-&&-peptidyl-cysteine S-nitrosylation-%%-GO:0051775-&&-response to redox state-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0051409-&&-response to nitrosative stress-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0046294-&&-formaldehyde catabolic process-%%-GO:0003016-&&-respiratory system process-%%-GO:0006069-&&-ethanol oxidation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0018467-&&-formaldehyde dehydrogenase activity-%%-GO:0004022-&&-alcohol dehydrogenase (NAD) activity-%%-GO:0005504-&&-fatty acid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0051903-&&-S-(hydroxymethyl)glutathione dehydrogenase activity	G:9606:ADH5			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00830-&&-Retinol metabolism-%%-hsa00071-&&-Fatty acid degradation	ADH5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADH5	0.37953716	0.15238095	17	4	FALSE	ADH5	ADH5	227	0	16	0	0.72753532	FALSE	1	ADH5	29908	0.09554713
791954	taxon:9606	2.57570506	9.74E-05	182811	1902	ankyrin 2	gene	biological_process-&-1&-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0030913-&&-paranodal junction assembly-%%-GO:0043268-&&-positive regulation of potassium ion transport-%%-GO:2001259-&&-positive regulation of cation channel activity-%%-GO:1901019-&&-regulation of calcium ion transmembrane transporter activity-%%-GO:0098910-&&-regulation of atrial cardiac muscle cell action potential-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0086004-&&-regulation of cardiac muscle cell contraction-%%-GO:0036309-&&-protein localization to M-band-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0070972-&&-protein localization to endoplasmic reticulum-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0003283-&&-atrial septum development-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0086046-&&-membrane depolarization during SA node cell action potential-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0033292-&&-T-tubule organization-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0086066-&&-atrial cardiac muscle cell to AV node cell communication-%%-GO:0098907-&&-regulation of SA node cell action potential-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0010882-&&-regulation of cardiac muscle contraction by calcium ion signaling-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0034613-&&-cellular protein localization-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0070296-&&-sarcoplasmic reticulum calcium ion transport-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0086015-&&-SA node cell action potential-%%-GO:0036371-&&-protein localization to T-tubule-%%-GO:0086070-&&-SA node cell to atrial cardiac muscle cell communication-%%-GO:1901018-&&-positive regulation of potassium ion transmembrane transporter activity-%%-GO:1901021-&&-positive regulation of calcium ion transmembrane transporter activity-%%-GO:0051597-&&-response to methylmercury-%%-GO:0086014-&&-atrial cardiac muscle cell action potential-%%-GO:0050821-&&-protein stabilization|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043034-&&-costamere-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031430-&&-M band-%%-GO:0005829-&&-cytosol-%%-GO:0042383-&&-sarcolemma-%%-GO:0005856-&&-cytoskeleton-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030315-&&-T-tubule-%%-GO:0014704-&&-intercalated disc-%%-GO:0005622-&&-intracellular-%%-GO:0030018-&&-Z disc-%%-GO:0031672-&&-A band|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0051117-&&-ATPase binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0019899-&&-enzyme binding	G:9606:ANK2			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	ANK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANK2	0.38824321	0.125	17	4	FALSE	ANK2	ANK2	244	0	17	0	0.73738249	FALSE	0	ANK2	100418	0.08886792
791990	taxon:9606	2.52103356	3.66E-05	166377	1902	ankyrin repeat domain 13A	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005770-&&-late endosome	G:9606:ANKRD13A				ANKRD13A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD13A	0.39666271	0.22794118	17	4	FALSE	ANKRD13A	ANKRD13A	322.8823529	0	17	0	0.74649441	FALSE	0	ANKRD13A	47900	0.10496413
791991	taxon:9606	2.73578068	2.80E-05	182760	1902	apolipoprotein D	gene	biological_process-&-1&-GO:2000098-&&-negative regulation of smooth muscle cell-matrix adhesion-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:0007420-&&-brain development-%%-GO:0007568-&&-aging-%%-GO:0042246-&&-tissue regeneration-%%-GO:0060588-&&-negative regulation of lipoprotein lipid oxidation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006869-&&-lipid transport-%%-GO:2000405-&&-negative regulation of T cell migration-%%-GO:0048678-&&-response to axon injury-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0042493-&&-response to drug-%%-GO:0042308-&&-negative regulation of protein import into nucleus-%%-GO:0001525-&&-angiogenesis-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0014012-&&-peripheral nervous system axon regeneration-%%-GO:1900016-&&-negative regulation of cytokine production involved in inflammatory response-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body-%%-GO:0022626-&&-cytosolic ribosome-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005515-&&-protein binding-%%-GO:0005319-&&-lipid transporter activity	G:9606:APOD				APOD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOD	0.36552638	0.04761905	17	4	FALSE	APOD	APOD	161.2666667	0	16	0	0.71070322	FALSE	1	APOD	32470	0.0912221
791997	taxon:9606	2.80983142	6.78E-05	182755	1902	kallikrein related peptidase 3	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0002778-&&-antibacterial peptide production|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0016811-&&-hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides-%%-GO:0005515-&&-protein binding	G:9606:KLK3	KLK3	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05200-&&-Pathways in cancer	KLK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK3	0.35589324	0.05147059	17	4	FALSE	KLK3	KLK3	92.76470588	0	17	0	0.69836143	FALSE	0	KLK3	63484	0.07030129
792015	taxon:9606	2.63305499	3.36E-05	182725	1902	BICD cargo adaptor 1	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:1900275-&&-negative regulation of phospholipase C activity-%%-GO:1900276-&&-regulation of proteinase activated receptor activity-%%-GO:0034063-&&-stress granule assembly-%%-GO:0016032-&&-viral process-%%-GO:0033365-&&-protein localization to organelle-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0072393-&&-microtubule anchoring at microtubule organizing center-%%-GO:0072385-&&-minus-end-directed organelle transport along microtubule-%%-GO:0008298-&&-intracellular mRNA localization-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:1900737-&&-negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045298-&&-tubulin complex-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0072517-&&-host cell viral assembly compartment-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0070840-&&-dynein complex binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0034452-&&-dynactin binding-%%-GO:0031871-&&-proteinase activated receptor binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:BICD1				BICD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BICD1	0.37978698	0.19117647	17	4	FALSE	BICD1	BICD1	199.6470588	0	17	0	0.72782417	FALSE	0	BICD1	35834	0.08277782
792029	taxon:9606	3.066173	3.31E-05	182712	1902	bone morphogenetic protein 2	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060039-&&-pericardium development-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0010922-&&-positive regulation of phosphatase activity-%%-GO:0043569-&&-negative regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0051042-&&-negative regulation of calcium-independent cell-cell adhesion-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0045165-&&-cell fate commitment-%%-GO:0035051-&&-cardiocyte differentiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0021537-&&-telencephalon development-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0048839-&&-inner ear development-%%-GO:0060129-&&-thyroid-stimulating hormone-secreting cell differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032348-&&-negative regulation of aldosterone biosynthetic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035054-&&-embryonic heart tube anterior/posterior pattern specification-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:2000726-&&-negative regulation of cardiac muscle cell differentiation-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0042482-&&-positive regulation of odontogenesis-%%-GO:0042487-&&-regulation of odontogenesis of dentin-containing tooth-%%-GO:0006029-&&-proteoglycan metabolic process-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0006954-&&-inflammatory response-%%-GO:1901522-&&-positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0060128-&&-corticotropin hormone secreting cell differentiation-%%-GO:2000065-&&-negative regulation of cortisol biosynthetic process-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0060804-&&-positive regulation of Wnt signaling pathway by BMP signaling pathway-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0072138-&&-mesenchymal cell proliferation involved in ureteric bud development-%%-GO:0021978-&&-telencephalon regionalization-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0010894-&&-negative regulation of steroid biosynthetic process-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0009790-&&-embryo development-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0001501-&&-skeletal system development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0048762-&&-mesenchymal cell differentiation-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0035630-&&-bone mineralization involved in bone maturation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030282-&&-bone mineralization-%%-GO:0003308-&&-negative regulation of Wnt signaling pathway involved in heart development-%%-GO:0003130-&&-BMP signaling pathway involved in heart induction-%%-GO:0007507-&&-heart development-%%-GO:0048468-&&-cell development-%%-GO:0031648-&&-protein destabilization-%%-GO:1902895-&&-positive regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060485-&&-mesenchyme development|cellular_component-&-1&-GO:0070724-&&-BMP receptor complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0039706-&&-co-receptor binding-%%-GO:0070700-&&-BMP receptor binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0019211-&&-phosphatase activator activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0004745-&&-retinol dehydrogenase activity	G:9606:BMP2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	BMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMP2	0.32613946	0.18095238	17	5	FALSE	BMP2	BMP2	31.33333333	0	16	0	0.65563783	FALSE	1	BMP2	29688	0.08547945
792102	taxon:9606	2.89175989	3.31E-05	182604	1902	collagen type III alpha 1 chain	gene	biological_process-&-1&-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0043588-&&-skin development-%%-GO:0007507-&&-heart development-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0007568-&&-aging-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0001501-&&-skeletal system development-%%-GO:0009314-&&-response to radiation-%%-GO:0050776-&&-regulation of immune response-%%-GO:0042060-&&-wound healing-%%-GO:0030168-&&-platelet activation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0060414-&&-aorta smooth muscle tissue morphogenesis-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0034097-&&-response to cytokine-%%-GO:0048565-&&-digestive tract development|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005586-&&-collagen type III trimer-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0046332-&&-SMAD binding	G:9606:COL3A1	COL3A1	TRUE	KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04611-&&-Platelet activation-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption	COL3A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL3A1	0.34581018	0.05882353	17	5	FALSE	COL3A1	COL3A1	67.35294118	0	17	0	0.68470669	FALSE	0	COL3A1	30612	0.06945208
792129	taxon:9606	2.79911769	2.43E-05	182550	1902	acyl-CoA oxidase 1	gene	biological_process-&-1&-GO:0019395-&&-fatty acid oxidation-%%-GO:0033540-&&-fatty acid beta-oxidation using acyl-CoA oxidase-%%-GO:0006693-&&-prostaglandin metabolic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0000038-&&-very long-chain fatty acid metabolic process-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003995-&&-acyl-CoA dehydrogenase activity-%%-GO:0003997-&&-acyl-CoA oxidase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0005102-&&-receptor binding-%%-GO:0030165-&&-PDZ domain binding	G:9606:ACOX1			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04146-&&-Peroxisome-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa00071-&&-Fatty acid degradation	ACOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACOX1	0.35725543	0.07352941	17	4	FALSE	ACOX1	ACOX1	104.4117647	0	17	0	0.70014705	FALSE	0	ACOX1	24602	0.07386364
792151	taxon:9606	2.71498346	1.04E-04	182513	1902	aminoacylase 1	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004046-&&-aminoacylase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ACY1			KEGG-&-1&-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01100-&&-Metabolic pathways	ACY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACY1	0.36832637	0.01904762	17	4	FALSE	ACY1	ACY1	160.6666667	0	16	0	0.71416942	FALSE	1	ACY1	110612	0.08507092
792152	taxon:9606	2.83220419	4.30E-05	182515	1902	activin A receptor type 2B	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0035265-&&-organ growth-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0030073-&&-insulin secretion-%%-GO:0007507-&&-heart development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0060841-&&-venous blood vessel development-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001822-&&-kidney development-%%-GO:0060840-&&-artery development-%%-GO:0060836-&&-lymphatic endothelial cell differentiation-%%-GO:0009791-&&-post-embryonic development-%%-GO:0032927-&&-positive regulation of activin receptor signaling pathway-%%-GO:0030324-&&-lung development-%%-GO:0060021-&&-palate development-%%-GO:0009749-&&-response to glucose-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0007498-&&-mesoderm development-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0031016-&&-pancreas development-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0007165-&&-signal transduction-%%-GO:0032924-&&-activin receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0019838-&&-growth factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0048185-&&-activin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0016362-&&-activin receptor activity, type II-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity	G:9606:ACVR2B	ACVR2B	TRUE	KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	ACVR2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVR2B	0.35308189	0.18382353	17	4	FALSE	ACVR2B	ACVR2B	91.11764706	0	17	0	0.69463263	FALSE	0	ACVR2B	36308	0.07634228
792190	taxon:9606	2.7099417	1.89E-05	182456	1902	Rho GDP dissociation inhibitor beta	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0071461-&&-cellular response to redox state-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:1901164-&&-negative regulation of trophoblast cell migration-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005094-&&-Rho GDP-dissociation inhibitor activity-%%-GO:0048365-&&-Rac GTPase binding	G:9606:ARHGDIB			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption	ARHGDIB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGDIB	0.36901163	0.13235294	17	4	FALSE	ARHGDIB	ARHGDIB	154.7058824	0	17	0	0.71500972	FALSE	0	ARHGDIB	25060	0.08125754
792224	taxon:9606	2.8025839	5.27E-06	166003	1902	NLR family pyrin domain containing 12	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050711-&&-negative regulation of interleukin-1 secretion-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0036336-&&-dendritic cell migration-%%-GO:0008588-&&-release of cytoplasmic sequestered NF-kappaB-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0043281-&&-regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045751-&&-negative regulation of Toll signaling pathway-%%-GO:0045409-&&-negative regulation of interleukin-6 biosynthetic process-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0045381-&&-regulation of interleukin-18 biosynthetic process-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0050710-&&-negative regulation of cytokine secretion-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008656-&&-cysteine-type endopeptidase activator activity involved in apoptotic process-%%-GO:0005515-&&-protein binding	G:9606:NLRP12			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	NLRP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP12	0.35681358	0.24264706	17	4	FALSE	NLRP12	NLRP12	138.8235294	0	17	0	0.69956935	FALSE	0	NLRP12	10184	0.10256076
792326	taxon:9606	2.95289113	3.86E-06	165836	1902	baculoviral IAP repeat containing 8	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:BIRC8			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04120-&&-Ubiquitin mediated proteolysis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer	BIRC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIRC8	0.33865116	0.19117647	17	4	FALSE	BIRC8	BIRC8	85.47058824	0	17	0	0.67451815	FALSE	0	BIRC8	7712	0.12579052
792437	taxon:9606	2.79864503	9.63E-06	182026	1902	NK2 homeobox 5	gene	biological_process-&-1&-GO:0051891-&&-positive regulation of cardioblast differentiation-%%-GO:0001947-&&-heart looping-%%-GO:0003221-&&-right ventricular cardiac muscle tissue morphogenesis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060971-&&-embryonic heart tube left/right pattern formation-%%-GO:0007512-&&-adult heart development-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0055015-&&-ventricular cardiac muscle cell development-%%-GO:0030097-&&-hemopoiesis-%%-GO:0048536-&&-spleen development-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0045214-&&-sarcomere organization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0060928-&&-atrioventricular node cell development-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0045823-&&-positive regulation of heart contraction-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0060043-&&-regulation of cardiac muscle cell proliferation-%%-GO:0003166-&&-bundle of His development-%%-GO:0003285-&&-septum secundum development-%%-GO:0055014-&&-atrial cardiac muscle cell development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0010735-&&-positive regulation of transcription via serum response element binding-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0001570-&&-vasculogenesis-%%-GO:0055005-&&-ventricular cardiac myofibril assembly-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0003211-&&-cardiac ventricle formation-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:0003278-&&-apoptotic process involved in heart morphogenesis-%%-GO:0003168-&&-Purkinje myocyte differentiation-%%-GO:0003342-&&-proepicardium development-%%-GO:0030878-&&-thyroid gland development-%%-GO:0003350-&&-pulmonary myocardium development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0060261-&&-positive regulation of transcription initiation from RNA polymerase II promoter-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0060929-&&-atrioventricular node cell fate commitment|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0010736-&&-serum response element binding-%%-GO:0001190-&&-transcriptional activator activity, RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:NKX2-5				NKX2-5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKX2-5	0.35731577	0.125	17	4	FALSE	NKX2-5	NKX2-5	119.7058824	0	17	0	0.70022583	FALSE	0	NKX2-5	16096	0.08445497
792596	taxon:9606	2.78147156	1.44E-05	181740	1902	dual specificity phosphatase 1	gene	biological_process-&-1&-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0009416-&&-response to light stimulus-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0033574-&&-response to testosterone-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0051592-&&-response to calcium ion-%%-GO:0090266-&&-regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051447-&&-negative regulation of meiotic cell cycle-%%-GO:0032355-&&-response to estradiol-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0001706-&&-endoderm formation-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051591-&&-response to cAMP-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0032870-&&-cellular response to hormone stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008330-&&-protein tyrosine/threonine phosphatase activity-%%-GO:0019838-&&-growth factor binding	G:9606:DUSP1			KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04010-&&-MAPK signaling pathway	DUSP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP1	0.35952192	0.17647059	17	4	FALSE	DUSP1	DUSP1	147.0588235	0	17	0	0.70308807	FALSE	0	DUSP1	19130	0.10046673
792643	taxon:9606	2.66629904	1.88E-05	181654	1902	scavenger receptor class B member 2	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0061024-&&-membrane organization-%%-GO:1904978-&&-regulation of endosome organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:1905123-&&-regulation of glucosylceramidase activity-%%-GO:0006622-&&-protein targeting to lysosome-%%-GO:1905671-&&-regulation of lysosome organization|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:SCARB2			KEGG-&-1&-hsa04142-&&-Lysosome	SCARB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCARB2	0.3750517	0.09558824	17	4	FALSE	SCARB2	SCARB2	173.5294118	0	17	0	0.72228349	FALSE	0	SCARB2	30026	0.07941042
792665	taxon:9606	2.94028675	1.85E-05	181593	1902	CD55 molecule (Cromer blood group)	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0031664-&&-regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0045730-&&-respiratory burst-%%-GO:0045916-&&-negative regulation of complement activation-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0035743-&&-CD4-positive, alpha-beta T cell cytokine production-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:2000516-&&-positive regulation of CD4-positive, alpha-beta T cell activation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:2000563-&&-positive regulation of CD4-positive, alpha-beta T cell proliferation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0009986-&&-cell surface-%%-GO:0101003-&&-ficolin-1-rich granule membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:CD55			KEGG-&-1&-hsa05416-&&-Viral myocarditis-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04610-&&-Complement and coagulation cascades	CD55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD55	0.34010288	0.03809524	17	4	FALSE	CD55	CD55	55.93333333	0	16	0	0.67661888	FALSE	1	CD55	15198	0.08283433
792818	taxon:9606	2.92594927	2.17E-05	181312	1902	endoglin	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:1905222-&&-atrioventricular canal morphogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0060348-&&-bone development-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0001570-&&-vasculogenesis-%%-GO:2000136-&&-regulation of cell proliferation involved in heart morphogenesis-%%-GO:0003273-&&-cell migration involved in endocardial cushion formation-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:1905065-&&-positive regulation of vascular smooth muscle cell differentiation-%%-GO:0001300-&&-chronological cell aging-%%-GO:0007155-&&-cell adhesion-%%-GO:0022009-&&-central nervous system vasculogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0031960-&&-response to corticosteroid-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0090500-&&-endocardial cushion to mesenchymal transition-%%-GO:0003198-&&-epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0010665-&&-regulation of cardiac muscle cell apoptotic process-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0055009-&&-atrial cardiac muscle tissue morphogenesis-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0048745-&&-smooth muscle tissue development-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0070278-&&-extracellular matrix constituent secretion-%%-GO:1905310-&&-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis-%%-GO:0003208-&&-cardiac ventricle morphogenesis-%%-GO:0097084-&&-vascular smooth muscle cell development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0048845-&&-venous blood vessel morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0003209-&&-cardiac atrium morphogenesis|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0070022-&&-transforming growth factor beta receptor complex-%%-GO:0072563-&&-endothelial microparticle-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0036122-&&-BMP binding-%%-GO:0005515-&&-protein binding-%%-GO:0048185-&&-activin binding-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005072-&&-transforming growth factor beta receptor, cytoplasmic mediator activity-%%-GO:0005534-&&-galactose binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0034713-&&-type I transforming growth factor beta receptor binding	G:9606:ENG	ENG	TRUE		ENG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENG	0.34176943	0.27619048	17	5	FALSE	ENG	ENG	70.26666667	0	16	0	0.67900846	FALSE	1	ENG	21520	0.08968457
792853	taxon:9606	2.80006302	1.48E-05	181264	1902	ERCC excision repair 5, endonuclease	gene	biological_process-&-1&-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0009650-&&-UV protection-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0010225-&&-response to UV-C-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0009411-&&-response to UV-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly|cellular_component-&-1&-GO:0016591-&&-DNA-directed RNA polymerase II, holoenzyme-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005675-&&-holo TFIIH complex-%%-GO:0005634-&&-nucleus-%%-GO:0005662-&&-DNA replication factor A complex|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0000405-&&-bubble DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004520-&&-endodeoxyribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:ERCC5			KEGG-&-1&-hsa03420-&&-Nucleotide excision repair	ERCC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERCC5	0.35713482	0.26470588	17	4	FALSE	ERCC5	ERCC5	119.4705882	0	17	0	0.6999895	FALSE	0	ERCC5	16950	0.08412843
792928	taxon:9606	2.70757838	4.99E-05	181124	1902	fatty acid binding protein 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2001245-&&-regulation of phosphatidylcholine biosynthetic process-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0070542-&&-response to fatty acid-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0044539-&&-long-chain fatty acid import-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0046320-&&-regulation of fatty acid oxidation-%%-GO:0071073-&&-positive regulation of phospholipid biosynthetic process-%%-GO:0032868-&&-response to insulin-%%-GO:0042493-&&-response to drug-%%-GO:0055091-&&-phospholipid homeostasis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016528-&&-sarcoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0036041-&&-long-chain fatty acid binding-%%-GO:0005324-&&-long-chain fatty acid transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0070538-&&-oleic acid binding-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0050543-&&-icosatetraenoic acid binding	G:9606:FABP3			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	FABP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FABP3	0.36933372	0.09558824	17	4	FALSE	FABP3	FABP3	146.5294118	0	17	0	0.7154036	FALSE	0	FABP3	48202	0.07464793
793011	taxon:9606	2.77847802	9.10E-06	180900	1902	G protein-coupled receptor 37	gene	biological_process-&-1&-GO:0031987-&&-locomotion involved in locomotory behavior-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0045964-&&-positive regulation of dopamine metabolic process-%%-GO:1903206-&&-negative regulation of hydrogen peroxide-induced cell death-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0043410-&&-positive regulation of MAPK cascade|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0031072-&&-heat shock protein binding-%%-GO:0036505-&&-prosaposin receptor activity-%%-GO:0008528-&&-G-protein coupled peptide receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0042277-&&-peptide binding	G:9606:GPR37			KEGG-&-1&-hsa05012-&&-Parkinson disease	GPR37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPR37	0.35990927	0.30147059	17	4	FALSE	GPR37	GPR37	165	0	17	0	0.703587	FALSE	0	GPR37	15624	0.11021548
793065	taxon:9606	2.65416732	2.98E-06	164431	1902	myosin light chain 6B	gene	biological_process-&-1&-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0005859-&&-muscle myosin complex-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016459-&&-myosin complex-%%-GO:0016461-&&-unconventional myosin complex|molecular_function-&-1&-GO:0003774-&&-motor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:MYL6B			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04530-&&-Tight junction	MYL6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL6B	0.376766	0.22058824	17	4	FALSE	MYL6B	MYL6B	270.3529412	0	17	0	0.72430545	FALSE	0	MYL6B	15356	0.11870624
793073	taxon:9606	2.91429022	9.68E-06	180804	1902	general transcription factor IIH subunit 2	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0009411-&&-response to UV-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006412-&&-translation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000438-&&-core TFIIH complex portion of holo TFIIH complex-%%-GO:0005634-&&-nucleus-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity	G:9606:GTF2H2			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair	GTF2H2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2H2	0.34313672	0.33823529	17	5	FALSE	GTF2H2	GTF2H2	68.70588235	0	17	0	0.68095163	FALSE	0	GTF2H2	10334	0.08286507
793082	taxon:9606	2.75295415	1.66E-05	180773	1902	follicle stimulating hormone receptor	gene	biological_process-&-1&-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0007292-&&-female gamete generation-%%-GO:0008585-&&-female gonad development-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0008584-&&-male gonad development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0042699-&&-follicle-stimulating hormone signaling pathway-%%-GO:0001545-&&-primary ovarian follicle growth-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0008406-&&-gonad development-%%-GO:0045670-&&-regulation of osteoclast differentiation|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0008528-&&-G-protein coupled peptide receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004963-&&-follicle-stimulating hormone receptor activity	G:9606:FSHR	FSHR	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	FSHR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FSHR	0.36324615	0.03676471	17	4	FALSE	FSHR	FSHR	143.2352941	0	17	0	0.70784097	FALSE	0	FSHR	22504	0.08735384
793123	taxon:9606	2.71608634	1.73E-05	164307	1902	heterogeneous nuclear ribonucleoprotein A1-like 2	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005681-&&-spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:HNRNPA1L2			KEGG-&-1&-hsa03040-&&-Spliceosome	HNRNPA1L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNRNPA1L2	0.36817681	0.26470588	17	4	FALSE	HNRNPA1L2	HNRNPA1L2	195.0588235	0	17	0	0.71398561	FALSE	0	HNRNPA1L2	22706	0.1021396
793194	taxon:9606	2.83188908	4.81E-06	164164	1902	methyltransferase like 21A	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0018022-&&-peptidyl-lysine methylation-%%-GO:0043462-&&-regulation of ATPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding	G:9606:METTL21A				METTL21A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL21A	0.35312118	0.26470588	17	5	FALSE	METTL21A	METTL21A	137.9411765	0	17	0	0.69468515	FALSE	0	METTL21A	8414	0.11385826
793212	taxon:9606	2.82149047	1.92E-05	180522	1902	heat shock transcription factor 4	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048468-&&-cell development-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0043010-&&-camera-type eye development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HSF4				HSF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSF4	0.3544226	0.15238095	17	5	FALSE	HSF4	HSF4	123.1333333	0	16	0	0.69641826	FALSE	1	HSF4	18288	0.09659329
793270	taxon:9606	2.80242634	1.35E-06	180392	1902	granzyme A	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0019835-&&-cytolysis-%%-GO:0032078-&&-negative regulation of endodeoxyribonuclease activity-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0006955-&&-immune response-%%-GO:0051354-&&-negative regulation of oxidoreductase activity|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:GZMA			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	GZMA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GZMA	0.35683364	0.18095238	17	4	FALSE	GZMA	GZMA	160.4	0	16	0	0.69959561	FALSE	1	GZMA	4508	0.11541787
793319	taxon:9606	2.80636521	2.15E-04	180322	1902	hepatocyte growth factor	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0060665-&&-regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0070572-&&-positive regulation of neuron projection regeneration-%%-GO:1902947-&&-regulation of tau-protein kinase activity-%%-GO:0001889-&&-liver development-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051450-&&-myoblast proliferation-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0050918-&&-positive chemotaxis-%%-GO:1901299-&&-negative regulation of hydrogen peroxide-mediated programmed cell death-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:1900744-&&-regulation of p38MAPK cascade-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0002576-&&-platelet degranulation-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0006508-&&-proteolysis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:HGF	HGF	TRUE	KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05144-&&-Malaria-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	HGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HGF	0.35633281	0.02857143	17	4	FALSE	HGF	HGF	106.4666667	0	16	0	0.69893913	FALSE	1	HGF	216822	0.07913239
793343	taxon:9606	2.58956988	6.66E-06	180265	1902	high mobility group nucleosomal binding domain 2	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0000785-&&-chromatin|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0031492-&&-nucleosomal DNA binding	G:9606:HMGN2				HMGN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGN2	0.38616452	0.17142857	17	4	FALSE	HMGN2	HMGN2	285.4666667	0	16	0	0.73507169	FALSE	1	HMGN2	20132	0.10817849
787067	taxon:9606	2.88593036	1.66E-05	180130	1902	interferon gamma receptor 1	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0007165-&&-signal transduction-%%-GO:0051607-&&-defense response to virus-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0031982-&&-vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004906-&&-interferon-gamma receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0019955-&&-cytokine binding	G:9606:IFNGR1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04217-&&-Necroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	IFNGR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNGR1	0.34650871	0.1978022	16	4	FALSE	IFNGR1	IFNGR1	102.5	0	15	0	0.68567827	FALSE	1	IFNGR1	19924	0.11436552
787068	taxon:9606	2.98361431	7.83E-05	180120	1902	insulin like growth factor 1	gene	biological_process-&-1&-GO:0001775-&&-cell activation-%%-GO:0009408-&&-response to heat-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0051450-&&-myoblast proliferation-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0008283-&&-cell proliferation-%%-GO:1904075-&&-positive regulation of trophectodermal cell proliferation-%%-GO:0035630-&&-bone mineralization involved in bone maturation-%%-GO:0014834-&&-skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0007517-&&-muscle organ development-%%-GO:0050821-&&-protein stabilization-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0009441-&&-glycolate metabolic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0030166-&&-proteoglycan biosynthetic process-%%-GO:0002576-&&-platelet degranulation-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0045445-&&-myoblast differentiation-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010560-&&-positive regulation of glycoprotein biosynthetic process-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0014896-&&-muscle hypertrophy-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0045821-&&-positive regulation of glycolytic process-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0045725-&&-positive regulation of glycogen biosynthetic process-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:0006260-&&-DNA replication-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0014904-&&-myotube cell development-%%-GO:0048009-&&-insulin-like growth factor receptor signaling pathway-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0060283-&&-negative regulation of oocyte development-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0034392-&&-negative regulation of smooth muscle cell apoptotic process-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0035867-&&-alphav-beta3 integrin-IGF-1-IGF1R complex-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0016942-&&-insulin-like growth factor binding protein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0070382-&&-exocytic vesicle-%%-GO:0042567-&&-insulin-like growth factor ternary complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005179-&&-hormone activity	G:9606:IGF1	IGF1	TRUE	KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05224-&&-Breast cancer-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	IGF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGF1	0.33516396	0.08333333	16	5	FALSE	IGF1	IGF1	35.25	0	16	0	0.66939762	FALSE	0	IGF1	99488	0.07819507
787100	taxon:9606	2.78682842	1.40E-04	180059	1902	interleukin 1 receptor accessory protein	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:1900006-&&-positive regulation of dendrite development-%%-GO:0006954-&&-inflammatory response-%%-GO:0042094-&&-interleukin-2 biosynthetic process-%%-GO:0006461-&&-protein complex assembly-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0006955-&&-immune response-%%-GO:0032754-&&-positive regulation of interleukin-5 production-%%-GO:0072602-&&-interleukin-4 secretion-%%-GO:0032736-&&-positive regulation of interleukin-13 production-%%-GO:0038172-&&-interleukin-33-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004908-&&-interleukin-1 receptor activity-%%-GO:0002114-&&-interleukin-33 receptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:1990782-&&-protein tyrosine kinase binding	G:9606:IL1RAP			KEGG-&-1&-hsa04659-&&-Th17 cell differentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL1RAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1RAP	0.35883085	0.175	16	4	FALSE	IL1RAP	IL1RAP	123.5625	0	16	0	0.70219526	FALSE	0	IL1RAP	152614	0.08486752
787166	taxon:9606	2.64266583	5.44E-05	179936	1902	lactotransferrin	gene	biological_process-&-1&-GO:0031665-&&-negative regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:0001895-&&-retina homeostasis-%%-GO:0006811-&&-ion transport-%%-GO:0032680-&&-regulation of tumor necrosis factor production-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:1902732-&&-positive regulation of chondrocyte proliferation-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000308-&&-negative regulation of tumor necrosis factor (ligand) superfamily member 11 production-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0006508-&&-proteolysis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:2001205-&&-negative regulation of osteoclast development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1900229-&&-negative regulation of single-species biofilm formation in or on host organism-%%-GO:0044793-&&-negative regulation by host of viral process-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0048525-&&-negative regulation of viral process-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019732-&&-antifungal humoral response-%%-GO:0032780-&&-negative regulation of ATPase activity-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0001503-&&-ossification-%%-GO:0033214-&&-iron assimilation by chelation and transport-%%-GO:0006959-&&-humoral immune response-%%-GO:0034145-&&-positive regulation of toll-like receptor 4 signaling pathway-%%-GO:1900159-&&-positive regulation of bone mineralization involved in bone maturation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0042581-&&-specific granule-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0043234-&&-protein complex-%%-GO:0097013-&&-phagocytic vesicle lumen-%%-GO:0030141-&&-secretory granule-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0008201-&&-heparin binding-%%-GO:0005506-&&-iron ion binding	G:9606:LTF				LTF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTF	0.37840577	0.075	16	4	FALSE	LTF	LTF	212.625	0	16	0	0.72622236	FALSE	0	LTF	52864	0.09107986
787174	taxon:9606	2.84023948	1.58E-05	179920	1902	mannose-6-phosphate receptor, cation dependent	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007165-&&-signal transduction-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0015761-&&-mannose transport-%%-GO:0033299-&&-secretion of lysosomal enzymes|cellular_component-&-1&-GO:0030904-&&-retromer complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane-%%-GO:0005770-&&-late endosome-%%-GO:0005768-&&-endosome-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0015578-&&-mannose transmembrane transporter activity-%%-GO:1905394-&&-retromer complex binding	G:9606:M6PR			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04142-&&-Lysosome	M6PR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-M6PR	0.35208299	0.075	16	5	FALSE	M6PR	M6PR	103.6875	0	16	0	0.69329342	FALSE	0	M6PR	18902	0.08742591
787206	taxon:9606	2.8158185	2.02E-05	179865	1902	microtubule affinity regulating kinase 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0001764-&&-neuron migration-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0070300-&&-phosphatidic acid binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0050321-&&-tau-protein kinase activity	G:9606:MARK1				MARK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARK1	0.35513653	0.23333333	16	5	FALSE	MARK1	MARK1	142.5625	0	16	0	0.69736358	FALSE	0	MARK1	23982	0.10693506
787375	taxon:9606	2.77075784	9.71E-06	163154	1902	methyltransferase like 21C	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0018022-&&-peptidyl-lysine methylation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:METTL21C				METTL21C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL21C	0.36091209	0.10833333	16	4	FALSE	METTL21C	METTL21C	148.9375	0	16	0	0.70487369	FALSE	0	METTL21C	15222	0.09613519
787391	taxon:9606	2.61603907	1.72E-05	179509	1902	myosin IXB	gene	biological_process-&-1&-GO:0030048-&&-actin filament-based movement-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0032011-&&-ARF protein signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005938-&&-cell cortex-%%-GO:0016459-&&-myosin complex-%%-GO:0005884-&&-actin filament-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003779-&&-actin binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0048495-&&-Roundabout binding-%%-GO:0043531-&&-ADP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYO9B				MYO9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO9B	0.38225729	0.08333333	16	4	FALSE	MYO9B	MYO9B	260.375	0	16	0	0.73066015	FALSE	0	MYO9B	34732	0.10361056
787534	taxon:9606	2.80857098	1.10E-05	162845	1902	cardiomyopathy associated 5	gene	cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CMYA5				CMYA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMYA5	0.35605296	0.01098901	16	5	FALSE	CMYA5	CMYA5	119.9285714	0	15	0	0.6985715	FALSE	1	CMYA5	15378	0.08748819
787603	taxon:9606	2.82842288	6.87E-06	179115	1902	nuclear factor I X	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:NFIX				NFIX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFIX	0.35355392	0.17582418	16	4	FALSE	NFIX	NFIX	142.6428571	0	15	0	0.69526285	FALSE	1	NFIX	11456	0.10981386
787721	taxon:9606	2.85977627	9.50E-06	178872	1902	septin 4	gene	biological_process-&-1&-GO:0048240-&&-sperm capacitation-%%-GO:0030382-&&-sperm mitochondrion organization-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0051301-&&-cell division-%%-GO:0007420-&&-brain development-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0007049-&&-cell cycle-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0031105-&&-septin complex-%%-GO:0043209-&&-myelin sheath-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0097227-&&-sperm annulus|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:SEPT4			KEGG-&-1&-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis	SEPT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT4	0.3496777	0.13186813	16	4	FALSE	SEPT4	SEPT4	103.6428571	0	15	0	0.69003729	FALSE	1	SEPT4	10876	0.09491014
787844	taxon:9606	2.85615251	2.38E-05	178725	1902	DnaJ heat shock protein family (Hsp40) member C3	gene	biological_process-&-1&-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0036494-&&-positive regulation of translation initiation in response to endoplasmic reticulum stress-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0051607-&&-defense response to virus-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0070417-&&-cellular response to cold|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0031205-&&-endoplasmic reticulum Sec complex-%%-GO:1903561-&&-extracellular vesicle|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:DNAJC3			KEGG-&-1&-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC3	0.35012136	0.225	16	4	FALSE	DNAJC3	DNAJC3	106.8125	0	16	0	0.69064125	FALSE	0	DNAJC3	37022	0.10014071
787860	taxon:9606	2.65968174	2.26E-05	178698	1902	protease, serine 1	gene	biological_process-&-1&-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0009235-&&-cobalamin metabolic process-%%-GO:0007586-&&-digestion-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0046872-&&-metal ion binding	G:9606:PRSS1	PRSS1	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05164-&&-Influenza A-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04974-&&-Protein digestion and absorption	PRSS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRSS1	0.37598484	0.14166667	16	4	FALSE	PRSS1	PRSS1	193.875	0	16	0	0.72338638	FALSE	0	PRSS1	28102	0.08725777
787910	taxon:9606	2.73073893	6.35E-05	178625	1902	prostaglandin D2 synthase	gene	biological_process-&-1&-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0006810-&&-transport-%%-GO:0045187-&&-regulation of circadian sleep/wake cycle, sleep|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005501-&&-retinoid binding-%%-GO:0004667-&&-prostaglandin-D synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding	G:9606:PTGDS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	PTGDS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGDS	0.36620125	0.07692308	16	4	FALSE	PTGDS	PTGDS	159.5	0	15	0	0.71154351	FALSE	1	PTGDS	54482	0.08911565
787958	taxon:9606	2.81392784	2.32E-06	178504	1902	paired box 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0021670-&&-lateral ventricle development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051573-&&-negative regulation of histone H3-K9 methylation-%%-GO:0006959-&&-humoral immune response-%%-GO:0030534-&&-adult behavior-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:PAX5			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	PAX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAX5	0.35537514	0.31868132	16	5	FALSE	PAX5	PAX5	167.5714286	0	15	0	0.69767869	FALSE	1	PAX5	5508	0.12708649
788312	taxon:9606	2.76098944	1.28E-05	177907	1902	S100 calcium binding protein A2	gene	biological_process-&-1&-GO:0043542-&&-endothelial cell migration|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0046914-&&-transition metal ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:S100A2				S100A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A2	0.362189	0.1978022	16	4	FALSE	S100A2	S100A2	168.2857143	0	15	0	0.70650176	FALSE	1	S100A2	13692	0.10290261
788365	taxon:9606	2.86623602	1.93E-05	177796	1902	selectin E	gene	biological_process-&-1&-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0050900-&&-leukocyte migration-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0030029-&&-actin filament-based process-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0002523-&&-leukocyte migration involved in inflammatory response-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0030863-&&-cortical cytoskeleton-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0043274-&&-phospholipase binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0033691-&&-sialic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0070492-&&-oligosaccharide binding	G:9606:SELE	SELE	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05144-&&-Malaria	SELE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELE	0.34888962	0.1	16	4	FALSE	SELE	SELE	87.625	0	16	0	0.68896066	FALSE	0	SELE	19108	0.08855223
788398	taxon:9606	2.77989601	6.97E-05	177742	1902	sulfotransferase family 1E member 1	gene	biological_process-&-1&-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0008210-&&-estrogen metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0051923-&&-sulfation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0050294-&&-steroid sulfotransferase activity-%%-GO:0005496-&&-steroid binding-%%-GO:0047894-&&-flavonol 3-sulfotransferase activity-%%-GO:0004062-&&-aryl sulfotransferase activity-%%-GO:0004304-&&-estrone sulfotransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008146-&&-sulfotransferase activity	G:9606:SULT1E1	SULT1E1	TRUE	KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis	SULT1E1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SULT1E1	0.35972569	0.04166667	16	4	FALSE	SULT1E1	SULT1E1	138.8125	0	16	0	0.70335066	FALSE	0	SULT1E1	70278	0.09147652
788486	taxon:9606	2.71939499	3.12E-05	177560	1902	synuclein beta	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:0050808-&&-synapse organization|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005739-&&-mitochondrion-%%-GO:0016234-&&-inclusion body|molecular_function-&-1&-GO:0004859-&&-phospholipase inhibitor activity-%%-GO:0005509-&&-calcium ion binding	G:9606:SNCB				SNCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNCB	0.36772885	0.16666667	16	4	FALSE	SNCB	SNCB	163.75	0	16	0	0.71343417	FALSE	0	SNCB	31972	0.08799033
788655	taxon:9606	2.81739404	6.04E-05	177247	1902	transforming growth factor beta 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032909-&&-regulation of transforming growth factor beta2 production-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0042704-&&-uterine wall breakdown-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0010936-&&-negative regulation of macrophage cytokine production-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0007411-&&-axon guidance-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0003407-&&-neural retina development-%%-GO:0001942-&&-hair follicle development-%%-GO:0003274-&&-endocardial cushion fusion-%%-GO:0001822-&&-kidney development-%%-GO:0009611-&&-response to wounding-%%-GO:0008584-&&-male gonad development-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0061037-&&-negative regulation of cartilage development-%%-GO:0007507-&&-heart development-%%-GO:0003184-&&-pulmonary valve morphogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0003222-&&-ventricular trabecula myocardium morphogenesis-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0008219-&&-cell death-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0048839-&&-inner ear development-%%-GO:0050778-&&-positive regulation of immune response-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0002576-&&-platelet degranulation-%%-GO:0060325-&&-face morphogenesis-%%-GO:0090091-&&-positive regulation of extracellular matrix disassembly-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0010002-&&-cardioblast differentiation-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0060065-&&-uterus development-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0003179-&&-heart valve morphogenesis-%%-GO:0007184-&&-SMAD protein import into nucleus-%%-GO:0001666-&&-response to hypoxia-%%-GO:0042637-&&-catagen-%%-GO:1903659-&&-regulation of complement-dependent cytotoxicity-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0009790-&&-embryo development-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0003215-&&-cardiac right ventricle morphogenesis-%%-GO:0016477-&&-cell migration-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048666-&&-neuron development-%%-GO:0051891-&&-positive regulation of cardioblast differentiation-%%-GO:0008347-&&-glial cell migration-%%-GO:0010693-&&-negative regulation of alkaline phosphatase activity-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0042476-&&-odontogenesis-%%-GO:0001525-&&-angiogenesis-%%-GO:1904888-&&-cranial skeletal system development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0045726-&&-positive regulation of integrin biosynthetic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:1904426-&&-positive regulation of GTP binding-%%-GO:0001654-&&-eye development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0051795-&&-positive regulation of catagen-%%-GO:0060021-&&-palate development-%%-GO:0048103-&&-somatic stem cell division-%%-GO:0001501-&&-skeletal system development-%%-GO:0016049-&&-cell growth-%%-GO:0001843-&&-neural tube closure-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1905006-&&-negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:1900182-&&-positive regulation of protein localization to nucleus-%%-GO:0001502-&&-cartilage condensation-%%-GO:1903701-&&-substantia propria of cornea development-%%-GO:0007435-&&-salivary gland morphogenesis-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0045823-&&-positive regulation of heart contraction-%%-GO:0048468-&&-cell development-%%-GO:2001241-&&-positive regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0048699-&&-generation of neurons-%%-GO:1902256-&&-regulation of apoptotic process involved in outflow tract morphogenesis-%%-GO:1905007-&&-positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0003289-&&-atrial septum primum morphogenesis-%%-GO:0035910-&&-ascending aorta morphogenesis-%%-GO:0042060-&&-wound healing-%%-GO:0070237-&&-positive regulation of activation-induced cell death of T cells-%%-GO:0042493-&&-response to drug-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0032570-&&-response to progesterone-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0061626-&&-pharyngeal arch artery morphogenesis-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0030424-&&-axon-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0034714-&&-type III transforming growth factor beta receptor binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding	G:9606:TGFB2	TGFB2	TRUE	KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05161-&&-Hepatitis B-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05144-&&-Malaria-%%-hsa05226-&&-Gastric cancer-%%-hsa05323-&&-Rheumatoid arthritis	TGFB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFB2	0.35493793	0.21978022	16	5	FALSE	TGFB2	TGFB2	114.2857143	0	15	0	0.69710099	FALSE	1	TGFB2	49724	0.08270404
788734	taxon:9606	2.78714353	6.56E-06	177083	1902	transcriptional repressor GATA binding 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006607-&&-NLS-bearing protein import into nucleus-%%-GO:0030154-&&-cell differentiation-%%-GO:0001501-&&-skeletal system development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032330-&&-regulation of chondrocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:TRPS1				TRPS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPS1	0.35879028	0.125	16	4	FALSE	TRPS1	TRPS1	142.3125	0	16	0	0.70214274	FALSE	0	TRPS1	12556	0.09601082
788749	taxon:9606	2.90074051	8.41E-06	177039	1902	zinc finger and BTB domain containing 25	gene	biological_process-&-1&-GO:0010467-&&-gene expression-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB25				ZBTB25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB25	0.34473956	0.04395604	16	5	FALSE	ZBTB25	ZBTB25	76.42857143	0	15	0	0.68320992	FALSE	1	ZBTB25	9018	0.08709201
788978	taxon:9606	2.84071215	1.21E-05	176476	1902	UBX domain protein 8	gene	biological_process-&-1&-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0007338-&&-single fertilization|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UBXN8				UBXN8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN8	0.3520244	0.1	16	4	FALSE	UBXN8	UBXN8	94.625	0	16	0	0.69321464	FALSE	0	UBXN8	14580	0.08249343
789129	taxon:9606	2.72538207	6.43E-06	176147	1902	histone cluster 1 H2B family member j	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BJ			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BJ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BJ	0.36692103	0.20833333	16	4	FALSE	HIST1H2BJ	HIST1H2BJ	240.5625	0	16	0	0.71243632	FALSE	0	HIST1H2BJ	17724	0.13024499
789280	taxon:9606	2.92720971	1.50E-05	175833	1902	transforming growth factor beta receptor associated protein 1	gene	biological_process-&-1&-GO:0008333-&&-endosome to lysosome transport-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0034058-&&-endosomal vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0016020-&&-membrane-%%-GO:0033263-&&-CORVET complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0046332-&&-SMAD binding	G:9606:TGFBRAP1				TGFBRAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBRAP1	0.34162226	0.18333333	16	4	FALSE	TGFBRAP1	TGFBRAP1	71.0625	0	16	0	0.67879838	FALSE	0	TGFBRAP1	13632	0.09309383
789284	taxon:9606	2.63305499	4.12E-05	175831	1902	N-myristoyltransferase 2	gene	biological_process-&-1&-GO:0075733-&&-intracellular transport of virus-%%-GO:0018008-&&-N-terminal peptidyl-glycine N-myristoylation-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004379-&&-glycylpeptide N-tetradecanoyltransferase activity	G:9606:NMT2				NMT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NMT2	0.37978698	0.16666667	16	4	FALSE	NMT2	NMT2	222.125	0	16	0	0.72782417	FALSE	0	NMT2	45546	0.09348673
789286	taxon:9606	2.80211123	1.69E-05	175827	1902	RecQ like helicase 4	gene	biological_process-&-1&-GO:1904354-&&-negative regulation of telomere capping-%%-GO:0006260-&&-DNA replication-%%-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006284-&&-base-excision repair-%%-GO:0000733-&&-DNA strand renaturation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006281-&&-DNA repair-%%-GO:0061820-&&-telomeric D-loop disassembly-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0032204-&&-regulation of telomere maintenance|cellular_component-&-1&-GO:0005694-&&-chromosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0000781-&&-chromosome, telomeric region|molecular_function-&-1&-GO:0036310-&&-annealing helicase activity-%%-GO:0061821-&&-telomeric D-loop binding-%%-GO:0043140-&&-ATP-dependent 3'-5' DNA helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0032357-&&-oxidized purine DNA binding-%%-GO:0000405-&&-bubble DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0009378-&&-four-way junction helicase activity-%%-GO:0004386-&&-helicase activity	G:9606:RECQL4				RECQL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RECQL4	0.35687377	0.09166667	16	5	FALSE	RECQL4	RECQL4	122.875	0	16	0	0.69964813	FALSE	0	RECQL4	19472	0.0871091
789294	taxon:9606	2.89601386	1.59E-05	175811	1902	heart and neural crest derivatives expressed 1	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0001707-&&-mesoderm formation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007507-&&-heart development-%%-GO:0001824-&&-blastocyst development-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0003218-&&-cardiac left ventricle formation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003144-&&-embryonic heart tube formation-%%-GO:0060707-&&-trophoblast giant cell differentiation-%%-GO:0003219-&&-cardiac right ventricle formation-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060485-&&-mesenchyme development-%%-GO:0060411-&&-cardiac septum morphogenesis|cellular_component-&-1&-GO:0090575-&&-RNA polymerase II transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:HAND1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	HAND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAND1	0.34530221	0.16483516	16	5	FALSE	HAND1	HAND1	84.07142857	0	15	0	0.68399769	FALSE	1	HAND1	13864	0.09348622
789303	taxon:9606	2.7694974	6.17E-05	175791	1902	integral membrane protein 2B	gene	biological_process-&-1&-GO:0042985-&&-negative regulation of amyloid precursor protein biosynthetic process-%%-GO:0007399-&&-nervous system development-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane-%%-GO:0030660-&&-Golgi-associated vesicle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031301-&&-integral component of organelle membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:ITM2B				ITM2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITM2B	0.36107635	0.025	16	4	FALSE	ITM2B	ITM2B	139.4375	0	16	0	0.70508377	FALSE	0	ITM2B	54354	0.0858891
789308	taxon:9606	2.73373247	1.40E-05	175776	1902	heart and neural crest derivatives expressed 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0061325-&&-cell proliferation involved in outflow tract morphogenesis-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060536-&&-cartilage morphogenesis-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0048538-&&-thymus development-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0061309-&&-cardiac neural crest cell development involved in outflow tract morphogenesis-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0003219-&&-cardiac right ventricle formation-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060982-&&-coronary artery morphogenesis-%%-GO:2000763-&&-positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process-%%-GO:0003278-&&-apoptotic process involved in heart morphogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0001967-&&-suckling behavior-%%-GO:0003357-&&-noradrenergic neuron differentiation-%%-GO:0007512-&&-adult heart development-%%-GO:0010463-&&-mesenchymal cell proliferation-%%-GO:0060021-&&-palate development-%%-GO:0003253-&&-cardiac neural crest cell migration involved in outflow tract morphogenesis-%%-GO:0007507-&&-heart development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0003266-&&-regulation of secondary heart field cardioblast proliferation-%%-GO:2000764-&&-positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001947-&&-heart looping-%%-GO:0043586-&&-tongue development-%%-GO:0001525-&&-angiogenesis-%%-GO:0034103-&&-regulation of tissue remodeling-%%-GO:0061032-&&-visceral serous pericardium development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0043234-&&-protein complex-%%-GO:0000790-&&-nuclear chromatin|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0033613-&&-activating transcription factor binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0003680-&&-AT DNA binding	G:9606:HAND2				HAND2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAND2	0.36580024	0.16483516	16	4	FALSE	HAND2	HAND2	181.1428571	0	15	0	0.71104459	FALSE	1	HAND2	20092	0.10174255
789329	taxon:9606	2.79045218	1.03E-05	175726	1902	tumor necrosis factor superfamily member 10	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:1902041-&&-regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006915-&&-apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0032868-&&-response to insulin-%%-GO:0097296-&&-activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008584-&&-male gonad development-%%-GO:1902042-&&-negative regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0046872-&&-metal ion binding	G:9606:TNFSF10			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05162-&&-Measles-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFSF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFSF10	0.35836486	0.35164835	16	4	FALSE	TNFSF10	TNFSF10	139	0	15	0	0.7015913	FALSE	1	TNFSF10	12178	0.09391624
789331	taxon:9606	2.82448401	3.00E-05	175719	1902	ADAM metallopeptidase domain 9	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0016477-&&-cell migration-%%-GO:0033631-&&-cell-cell adhesion mediated by integrin-%%-GO:0051549-&&-positive regulation of keratinocyte migration-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0010042-&&-response to manganese ion-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0034616-&&-response to laminar fluid shear stress-%%-GO:0042117-&&-monocyte activation-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0051088-&&-PMA-inducible membrane protein ectodomain proteolysis-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0051592-&&-response to calcium ion-%%-GO:0034241-&&-positive regulation of macrophage fusion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031233-&&-intrinsic component of external side of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016323-&&-basolateral plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0043236-&&-laminin binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005518-&&-collagen binding-%%-GO:0008237-&&-metallopeptidase activity	G:9606:ADAM9				ADAM9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAM9	0.35404697	0.025	16	4	FALSE	ADAM9	ADAM9	95.375	0	16	0	0.69591933	FALSE	0	ADAM9	32122	0.07426471
789377	taxon:9606	2.75988656	6.32E-06	175630	1902	LRR binding FLII interacting protein 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0030275-&&-LRR domain binding-%%-GO:0005515-&&-protein binding	G:9606:LRRFIP2				LRRFIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRFIP2	0.36233373	0.36666667	16	5	FALSE	LRRFIP2	LRRFIP2	172.4375	0	16	0	0.70668557	FALSE	0	LRRFIP2	11744	0.10544244
789468	taxon:9606	2.68378762	1.29E-05	175399	1902	CDC42 binding protein kinase beta	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016477-&&-cell migration-%%-GO:0031532-&&-actin cytoskeleton reorganization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005911-&&-cell-cell junction-%%-GO:0031252-&&-cell leading edge-%%-GO:0042641-&&-actomyosin-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:CDC42BPB				CDC42BPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC42BPB	0.37260773	0.05833333	16	4	FALSE	CDC42BPB	CDC42BPB	178.25	0	16	0	0.71936873	FALSE	0	CDC42BPB	22166	0.08448194
789532	taxon:9606	2.67134079	2.04E-05	175246	1902	serine palmitoyltransferase long chain base subunit 1	gene	biological_process-&-1&-GO:0006665-&&-sphingolipid metabolic process-%%-GO:0046512-&&-sphingosine biosynthetic process-%%-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0046511-&&-sphinganine biosynthetic process-%%-GO:1904504-&&-positive regulation of lipophagy-%%-GO:0046513-&&-ceramide biosynthetic process-%%-GO:0006686-&&-sphingomyelin biosynthetic process|cellular_component-&-1&-GO:0017059-&&-serine C-palmitoyltransferase complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0035339-&&-SPOTS complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004758-&&-serine C-palmitoyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:SPTLC1	SPTLC1	TRUE	KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	SPTLC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTLC1	0.37434385	0.06666667	16	4	FALSE	SPTLC1	SPTLC1	194.5625	0	16	0	0.7214432	FALSE	0	SPTLC1	37192	0.09034884
789547	taxon:9606	2.73546557	7.37E-06	175208	1902	malectin	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0030246-&&-carbohydrate binding	G:9606:MLEC				MLEC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLEC	0.36556848	0.11666667	16	4	FALSE	MLEC	MLEC	193.4375	0	16	0	0.71075574	FALSE	0	MLEC	20584	0.10720727
789604	taxon:9606	2.63715141	3.83E-05	175081	1902	glutamine-fructose-6-phosphate transaminase 2	gene	biological_process-&-1&-GO:0006541-&&-glutamine metabolic process-%%-GO:0006002-&&-fructose 6-phosphate metabolic process-%%-GO:0006048-&&-UDP-N-acetylglucosamine biosynthetic process-%%-GO:0006112-&&-energy reserve metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0097367-&&-carbohydrate derivative binding-%%-GO:0005515-&&-protein binding-%%-GO:0004360-&&-glutamine-fructose-6-phosphate transaminase (isomerizing) activity	G:9606:GFPT2	GFPT2	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa04931-&&-Insulin resistance	GFPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFPT2	0.37919704	0.14166667	16	4	FALSE	GFPT2	GFPT2	232.5	0	16	0	0.72714143	FALSE	0	GFPT2	39088	0.09744652
789648	taxon:9606	2.72270364	4.64E-06	174977	1902	sex comb on midleg-like 2 (Drosophila)	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031519-&&-PcG protein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SCML2				SCML2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCML2	0.36728199	0.28333333	16	5	FALSE	SCML2	SCML2	235.25	0	16	0	0.71288273	FALSE	0	SCML2	11186	0.12371778
789690	taxon:9606	2.70978415	5.71E-06	174890	1902	CAP, adenylate cyclase-associated protein, 2 (yeast)	gene	biological_process-&-1&-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0007165-&&-signal transduction-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0000902-&&-cell morphogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030864-&&-cortical actin cytoskeleton|molecular_function-&-1&-GO:0008179-&&-adenylate cyclase binding-%%-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CAP2				CAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAP2	0.36903308	0.1978022	16	4	FALSE	CAP2	CAP2	193.5	0	15	0	0.71503598	FALSE	1	CAP2	11864	0.10086445
789716	taxon:9606	2.694974	9.18E-06	174834	1902	ribonuclease P/MRP subunit p30	gene	biological_process-&-1&-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0001682-&&-tRNA 5'-leader removal-%%-GO:0006364-&&-rRNA processing-%%-GO:0008033-&&-tRNA processing|cellular_component-&-1&-GO:0005655-&&-nucleolar ribonuclease P complex-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0004526-&&-ribonuclease P activity-%%-GO:0005515-&&-protein binding	G:9606:RPP30			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03013-&&-RNA transport	RPP30	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPP30	0.37106109	0.15833333	16	4	FALSE	RPP30	RPP30	231.4375	0	16	0	0.71750433	FALSE	0	RPP30	19392	0.11303127
789756	taxon:9606	2.83882149	1.45E-05	174763	1902	tripartite motif containing 10	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TRIM10				TRIM10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM10	0.35225885	0.04395604	16	5	FALSE	TRIM10	TRIM10	122.1428571	0	15	0	0.69352975	FALSE	1	TRIM10	15954	0.10239298
789925	taxon:9606	2.82700488	4.65E-06	174340	1902	glucocorticoid modulatory element binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:GMEB1				GMEB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMEB1	0.35373126	0.21978022	16	4	FALSE	GMEB1	GMEB1	141.6428571	0	15	0	0.69549919	FALSE	1	GMEB1	8968	0.11039973
790166	taxon:9606	2.67527966	4.48E-05	173730	1902	F-box protein 21	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXO21				FBXO21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO21	0.3737927	0.2	16	4	FALSE	FBXO21	FBXO21	240.4375	0	16	0	0.72078672	FALSE	0	FBXO21	51120	0.11096998
790197	taxon:9606	2.79470616	2.19E-05	173670	1902	zinc finger protein 423	gene	biological_process-&-1&-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF423				ZNF423	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF423	0.35781937	0.11666667	16	5	FALSE	ZNF423	ZNF423	134.6875	0	16	0	0.70088231	FALSE	0	ZNF423	25504	0.09329459
790234	taxon:9606	2.70017331	8.26E-06	173562	1902	cleavage stimulation factor subunit 2 tau variant	gene	biological_process-&-1&-GO:0031124-&&-mRNA 3'-end processing-%%-GO:0098789-&&-pre-mRNA cleavage required for polyadenylation-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005847-&&-mRNA cleavage and polyadenylation specificity factor complex-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0005515-&&-protein binding	G:9606:CSTF2T			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	CSTF2T	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSTF2T	0.3703466	0.25	16	4	FALSE	CSTF2T	CSTF2T	170.6875	0	16	0	0.71663778	FALSE	0	CSTF2T	18038	0.08657995
790238	taxon:9606	2.63809674	2.26E-05	173554	1902	ankyrin repeat and sterile alpha motif domain containing 1A	gene	biological_process-&-1&-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:1901187-&&-regulation of ephrin receptor signaling pathway-%%-GO:0006929-&&-substrate-dependent cell migration-%%-GO:0016322-&&-neuron remodeling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0046875-&&-ephrin receptor binding-%%-GO:0005515-&&-protein binding	G:9606:ANKS1A				ANKS1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKS1A	0.37906116	0.16666667	16	4	FALSE	ANKS1A	ANKS1A	224.6875	0	16	0	0.72698388	FALSE	0	ANKS1A	29124	0.09523431
790456	taxon:9606	2.70222152	7.34E-06	172796	1902	chromodomain helicase DNA binding protein 5	gene	biological_process-&-1&-GO:0043967-&&-histone H4 acetylation-%%-GO:1901798-&&-positive regulation of signal transduction by p53 class mediator-%%-GO:0021895-&&-cerebral cortex neuron differentiation-%%-GO:0060850-&&-regulation of transcription involved in cell fate commitment-%%-GO:0098532-&&-histone H3-K27 trimethylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0035093-&&-spermatogenesis, exchange of chromosomal proteins|cellular_component-&-1&-GO:0000792-&&-heterochromatin-%%-GO:0016581-&&-NuRD complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008026-&&-ATP-dependent helicase activity-%%-GO:0061628-&&-H3K27me3 modified histone binding-%%-GO:0008270-&&-zinc ion binding	G:9606:CHD5				CHD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD5	0.37006589	0.575	16	4	FALSE	CHD5	CHD5	207.5625	0	16	0	0.71629641	FALSE	0	CHD5	15886	0.10372939
790555	taxon:9606	2.72853317	5.87E-06	172231	1902	myoferlin	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0030947-&&-regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0034605-&&-cellular response to heat-%%-GO:0001778-&&-plasma membrane repair-%%-GO:0008015-&&-blood circulation-%%-GO:0007520-&&-myoblast fusion|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding	G:9606:MYOF				MYOF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOF	0.36649729	0.20833333	16	4	FALSE	MYOF	MYOF	219.1875	0	16	0	0.71191114	FALSE	0	MYOF	15988	0.12003425
790642	taxon:9606	2.6483378	7.92E-06	171684	1902	DNA damage inducible transcript 4	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0048011-&&-neurotrophin TRK receptor signaling pathway-%%-GO:1902532-&&-negative regulation of intracellular signal transduction-%%-GO:0007420-&&-brain development-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0001764-&&-neuron migration-%%-GO:0008283-&&-cell proliferation-%%-GO:1901216-&&-positive regulation of neuron death-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0051607-&&-defense response to virus-%%-GO:0043241-&&-protein complex disassembly-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0071889-&&-14-3-3 protein binding	G:9606:DDIT4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04140-&&-Autophagy - animal-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04150-&&-mTOR signaling pathway	DDIT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDIT4	0.37759534	0.2	16	4	FALSE	DDIT4	DDIT4	257.625	0	16	0	0.72527703	FALSE	0	DDIT4	18602	0.1118321
790670	taxon:9606	2.68095163	2.50E-06	171536	1902	MACRO domain containing 1	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0051725-&&-protein de-ADP-ribosylation-%%-GO:0042278-&&-purine nucleoside metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0016798-&&-hydrolase activity, acting on glycosyl bonds-%%-GO:0019213-&&-deacetylase activity-%%-GO:0005515-&&-protein binding	G:9606:MACROD1				MACROD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MACROD1	0.37300188	0.25	16	4	FALSE	MACROD1	MACROD1	230.75	0	16	0	0.71984139	FALSE	0	MACROD1	6792	0.11058845
790716	taxon:9606	2.88734835	4.61E-05	171396	1902	thioredoxin related transmembrane protein 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0005623-&&-cell|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TMX2				TMX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMX2	0.34633854	0	16	4	FALSE	TMX2	TMX2	74.875	0	16	0	0.68544194	FALSE	0	TMX2	38934	0.07336147
790741	taxon:9606	2.67449189	1.99E-05	171346	1902	angiopoietin like 4	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051005-&&-negative regulation of lipoprotein lipase activity-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ANGPTL4	ANGPTL4	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa03320-&&-PPAR signaling pathway	ANGPTL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANGPTL4	0.3739028	0.15833333	16	4	FALSE	ANGPTL4	ANGPTL4	195.375	0	16	0	0.72091802	FALSE	0	ANGPTL4	33050	0.09208196
790780	taxon:9606	2.82921065	1.58E-05	171229	1902	bifunctional apoptosis regulator	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:1903895-&&-negative regulation of IRE1-mediated unfolded protein response-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051865-&&-protein autoubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0089720-&&-caspase binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:BFAR				BFAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BFAR	0.35345548	0.175	16	4	FALSE	BFAR	BFAR	127.5	0	16	0	0.69513156	FALSE	0	BFAR	20158	0.10432023
790825	taxon:9606	2.8972743	2.77E-05	171069	1902	NAD(P) dependent steroid dehydrogenase-like	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0001942-&&-hair follicle development-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0007224-&&-smoothened signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0047012-&&-sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity-%%-GO:0000252-&&-C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity-%%-GO:0003854-&&-3-beta-hydroxy-delta5-steroid dehydrogenase activity	G:9606:NSDHL			KEGG-&-1&-hsa00100-&&-Steroid biosynthesis-%%-hsa01100-&&-Metabolic pathways	NSDHL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSDHL	0.34515199	0.03333333	16	5	FALSE	NSDHL	NSDHL	92.5	0	16	0	0.68378762	FALSE	0	NSDHL	33754	0.09543919
790847	taxon:9606	2.93556011	3.23E-05	154571	1902	POTE ankyrin domain family member F	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle	G:9606:POTEF				POTEF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POTEF	0.34065049	0	16	5	FALSE	POTEF	POTEF	55.625	0	16	0	0.67740665	FALSE	0	POTEF	28636	0.07371795
790964	taxon:9606	2.81503072	1.53E-05	170582	1902	protein phosphatase 2 regulatory subunit B''gamma	gene	biological_process-&-1&-GO:0001782-&&-B cell homeostasis-%%-GO:0045579-&&-positive regulation of B cell differentiation-%%-GO:0051900-&&-regulation of mitochondrial depolarization-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0043029-&&-T cell homeostasis-%%-GO:0002759-&&-regulation of antimicrobial humoral response-%%-GO:0030865-&&-cortical cytoskeleton organization-%%-GO:0048536-&&-spleen development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome-%%-GO:0005819-&&-spindle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PPP2R3C			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa03015-&&-mRNA surveillance pathway	PPP2R3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R3C	0.35523591	0.125	16	4	FALSE	PPP2R3C	PPP2R3C	115.625	0	16	0	0.69749488	FALSE	0	PPP2R3C	16258	0.0894104
791034	taxon:9606	2.75200882	1.40E-05	170289	1902	family with sequence similarity 208 member B	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM208B				FAM208B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM208B	0.36337093	0.05494505	16	4	FALSE	FAM208B	FAM208B	162.7142857	0	15	0	0.70799853	FALSE	1	FAM208B	21302	0.0939414
791212	taxon:9606	2.78131401	9.27E-06	169723	1902	selenoprotein S	gene	biological_process-&-1&-GO:2000110-&&-negative regulation of macrophage apoptotic process-%%-GO:0006983-&&-ER overload response-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0002865-&&-negative regulation of acute inflammatory response to antigenic stimulus-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0051771-&&-negative regulation of nitric-oxide synthase biosynthetic process-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0006111-&&-regulation of gluconeogenesis-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0051775-&&-response to redox state-%%-GO:0080164-&&-regulation of nitric oxide metabolic process-%%-GO:0030970-&&-retrograde protein transport, ER to cytosol-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0009749-&&-response to glucose|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0036502-&&-Derlin-1-VIMP complex-%%-GO:0034362-&&-low-density lipoprotein particle-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex|molecular_function-&-1&-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0016209-&&-antioxidant activity-%%-GO:0004872-&&-receptor activity-%%-GO:0051117-&&-ATPase binding	G:9606:SELENOS			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SELENOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELENOS	0.35954229	0.35	16	4	FALSE	SELENOS	SELENOS	133.125	0	16	0	0.70311433	FALSE	0	SELENOS	14076	0.08974359
791297	taxon:9606	2.5041752	9.55E-06	169300	1902	KIAA1524	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:KIAA1524				KIAA1524	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA1524	0.39933308	0.175	16	4	FALSE	KIAA1524	KIAA1524	366.625	0	16	0	0.74930413	FALSE	0	KIAA1524	32136	0.11505102
791364	taxon:9606	2.52197889	3.22E-05	168964	1902	erythrocyte membrane protein band 4.1 like 5	gene	biological_process-&-1&-GO:0048617-&&-embryonic foregut morphogenesis-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0007492-&&-endoderm development-%%-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0031032-&&-actomyosin structure organization-%%-GO:0006931-&&-substrate-dependent cell migration, cell attachment to substrate-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0001839-&&-neural plate morphogenesis-%%-GO:0032525-&&-somite rostral/caudal axis specification-%%-GO:0007509-&&-mesoderm migration involved in gastrulation-%%-GO:0007398-&&-ectoderm development-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0048339-&&-paraxial mesoderm development-%%-GO:0048319-&&-axial mesoderm morphogenesis-%%-GO:0070201-&&-regulation of establishment of protein localization-%%-GO:0009826-&&-unidimensional cell growth-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0003383-&&-apical constriction-%%-GO:0070986-&&-left/right axis specification-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0019904-&&-protein domain specific binding	G:9606:EPB41L5				EPB41L5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB41L5	0.39651403	0.1	16	4	FALSE	EPB41L5	EPB41L5	307	0	16	0	0.74633685	FALSE	0	EPB41L5	43820	0.09978855
791393	taxon:9606	2.61336064	1.28E-05	168822	1902	myozenin 1	gene	biological_process-&-1&-GO:0030239-&&-myofibril assembly|cellular_component-&-1&-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0031143-&&-pseudopodium-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0051373-&&-FATZ binding-%%-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031433-&&-telethonin binding	G:9606:MYOZ1				MYOZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOZ1	0.38264906	0.15833333	16	4	FALSE	MYOZ1	MYOZ1	217.6875	0	16	0	0.73110656	FALSE	0	MYOZ1	25468	0.08745982
791418	taxon:9606	2.54340633	1.40E-05	168708	1902	5'-nucleotidase domain containing 2	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008253-&&-5'-nucleotidase activity	G:9606:NT5DC2				NT5DC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NT5DC2	0.39317351	0.09166667	16	4	FALSE	NT5DC2	NT5DC2	351.25	0	16	0	0.74276561	FALSE	0	NT5DC2	40284	0.11924677
791446	taxon:9606	2.83188908	1.76E-05	168610	1902	cysteine rich with EGF like domains 1	gene	biological_process-&-1&-GO:0003279-&&-cardiac septum development-%%-GO:0003197-&&-endocardial cushion development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:CRELD1				CRELD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRELD1	0.35312118	0.05833333	16	4	FALSE	CRELD1	CRELD1	106.375	0	16	0	0.69468515	FALSE	0	CRELD1	21674	0.08690525
791490	taxon:9606	2.86576335	8.04E-06	168415	1902	modulator of apoptosis 1	gene	biological_process-&-1&-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0008630-&&-intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:MOAP1				MOAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOAP1	0.34894717	0.08791209	16	4	FALSE	MOAP1	MOAP1	94.78571429	0	15	0	0.68903944	FALSE	1	MOAP1	10994	0.09187648
791533	taxon:9606	2.80983142	8.40E-06	168222	1902	methyltransferase like 17	gene	biological_process-&-1&-GO:0032259-&&-methylation-%%-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008168-&&-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:METTL17				METTL17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL17	0.35589324	0.04166667	16	4	FALSE	METTL17	METTL17	116.375	0	16	0	0.69836143	FALSE	0	METTL17	16488	0.08358868
791567	taxon:9606	2.61855995	2.05E-06	167991	1902	tubulin alpha 4b	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003674-&&-molecular_function-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBA4B				TUBA4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBA4B	0.38188929	0.54166667	16	4	FALSE	TUBA4B	TUBA4B	314.5625	0	16	0	0.73024001	FALSE	0	TUBA4B	6958	0.12737951
791612	taxon:9606	2.79139751	1.61E-05	167818	1902	F-box protein 31	gene	biological_process-&-1&-GO:0031145-&&-anaphase-promoting complex-dependent catabolic process-%%-GO:0031571-&&-mitotic G1 DNA damage checkpoint-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:2001224-&&-positive regulation of neuron migration-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0030332-&&-cyclin binding	G:9606:FBXO31				FBXO31	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO31	0.35824349	0.16666667	16	4	FALSE	FBXO31	FBXO31	150.875	0	16	0	0.70143375	FALSE	0	FBXO31	19052	0.10224185
791972	taxon:9606	2.75768079	3.89E-05	182781	1902	amyloid P component, serum	gene	biological_process-&-1&-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0006457-&&-protein folding-%%-GO:1903016-&&-negative regulation of exo-alpha-sialidase activity-%%-GO:0006953-&&-acute-phase response-%%-GO:0044869-&&-negative regulation by host of viral exo-alpha-sialidase activity-%%-GO:0045087-&&-innate immune response-%%-GO:0045656-&&-negative regulation of monocyte differentiation-%%-GO:0044871-&&-negative regulation by host of viral glycoprotein metabolic process-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:1903019-&&-negative regulation of glycoprotein metabolic process-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0048525-&&-negative regulation of viral process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0046790-&&-virion binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0001849-&&-complement component C1q binding	G:9606:APCS				APCS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APCS	0.36262355	0.0989011	16	4	FALSE	APCS	APCS	153.4285714	0	15	0	0.7070532	FALSE	1	APCS	33848	0.09520846
792011	taxon:9606	2.608634	2.52E-05	166348	1902	tetratricopeptide repeat domain 5	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:TTC5				TTC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC5	0.38334239	0.15	16	4	FALSE	TTC5	TTC5	299.6875	0	16	0	0.73189433	FALSE	0	TTC5	34862	0.11803093
792035	taxon:9606	2.76965496	1.29E-04	182700	1902	BCL2 interacting protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0016320-&&-endoplasmic reticulum membrane fusion-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097194-&&-execution phase of apoptosis-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0031201-&&-SNARE complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005484-&&-SNAP receptor activity	G:9606:BNIP1			KEGG-&-1&-hsa04130-&&-SNARE interactions in vesicular transport	BNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNIP1	0.36105581	0.0989011	16	4	FALSE	BNIP1	BNIP1	137.3571429	0	15	0	0.70505751	FALSE	1	BNIP1	116856	0.08614501
792042	taxon:9606	2.67496455	1.18E-05	182692	1902	biphenyl hydrolase like	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0006520-&&-cellular amino acid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0047658-&&-alpha-amino-acid esterase activity	G:9606:BPHL				BPHL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BPHL	0.37383673	0.18333333	16	4	FALSE	BPHL	BPHL	227.25	0	16	0	0.72083924	FALSE	0	BPHL	19886	0.10532568
792088	taxon:9606	2.69922798	9.46E-06	166253	1902	serpin family B member 12	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0042177-&&-negative regulation of protein catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINB12				SERPINB12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB12	0.3704763	0.11666667	16	4	FALSE	SERPINB12	SERPINB12	268.375	0	16	0	0.71679534	FALSE	0	SERPINB12	16970	0.1335992
792135	taxon:9606	2.67953364	1.19E-05	182532	1902	actin, gamma 2, smooth muscle, enteric	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006936-&&-muscle contraction-%%-GO:0090131-&&-mesenchyme migration|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0032982-&&-myosin filament-%%-GO:0071944-&&-cell periphery-%%-GO:0070062-&&-extracellular exosome-%%-GO:0044297-&&-cell body-%%-GO:0030027-&&-lamellipodium-%%-GO:0072562-&&-blood microparticle-%%-GO:0030175-&&-filopodium-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:ACTG2			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction	ACTG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTG2	0.37319927	0.09166667	16	4	FALSE	ACTG2	ACTG2	214.75	0	16	0	0.72007773	FALSE	0	ACTG2	20278	0.10228898
792149	taxon:9606	2.99417047	2.42E-05	182516	1902	activin A receptor type 2A	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0007178-&&-transmembrane receptor protein serine/threonine kinase signaling pathway-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0043084-&&-penile erection-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0045648-&&-positive regulation of erythrocyte differentiation-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0060011-&&-Sertoli cell proliferation-%%-GO:0032927-&&-positive regulation of activin receptor signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0001702-&&-gastrulation with mouth forming second-%%-GO:0030510-&&-regulation of BMP signaling pathway-%%-GO:0007498-&&-mesoderm development-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0042713-&&-sperm ejaculation-%%-GO:0007368-&&-determination of left/right symmetry|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0009986-&&-cell surface-%%-GO:0005737-&&-cytoplasm-%%-GO:0034673-&&-inhibin-betaglycan-ActRII complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0017002-&&-activin-activated receptor activity-%%-GO:0048185-&&-activin binding-%%-GO:0034711-&&-inhibin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0098821-&&-BMP receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0015026-&&-coreceptor activity	G:9606:ACVR2A	ACVR2A	TRUE	KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	ACVR2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVR2A	0.33398232	0.125	16	5	FALSE	ACVR2A	ACVR2A	40.875	0	16	0	0.66763825	FALSE	0	ACVR2A	18950	0.07894737
792156	taxon:9606	2.72081298	4.73E-05	182510	1902	adenosine deaminase	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0060407-&&-negative regulation of penile erection-%%-GO:0048541-&&-Peyer's patch development-%%-GO:0006154-&&-adenosine catabolic process-%%-GO:0060169-&&-negative regulation of adenosine receptor signaling pathway-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0033632-&&-regulation of cell-cell adhesion mediated by integrin-%%-GO:0070244-&&-negative regulation of thymocyte apoptotic process-%%-GO:0006157-&&-deoxyadenosine catabolic process-%%-GO:0048286-&&-lung alveolus development-%%-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0009168-&&-purine ribonucleoside monophosphate biosynthetic process-%%-GO:0042110-&&-T cell activation-%%-GO:0002314-&&-germinal center B cell differentiation-%%-GO:0001890-&&-placenta development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001889-&&-liver development-%%-GO:0002636-&&-positive regulation of germinal center formation-%%-GO:0002686-&&-negative regulation of leukocyte migration-%%-GO:0007155-&&-cell adhesion-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0002906-&&-negative regulation of mature B cell apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0046101-&&-hypoxanthine biosynthetic process-%%-GO:0050862-&&-positive regulation of T cell receptor signaling pathway-%%-GO:0001821-&&-histamine secretion-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0048566-&&-embryonic digestive tract development-%%-GO:0070256-&&-negative regulation of mucus secretion-%%-GO:0046061-&&-dATP catabolic process-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0033197-&&-response to vitamin E-%%-GO:0043278-&&-response to morphine-%%-GO:0046638-&&-positive regulation of alpha-beta T cell differentiation-%%-GO:0007568-&&-aging-%%-GO:0046103-&&-inosine biosynthetic process-%%-GO:0032261-&&-purine nucleotide salvage-%%-GO:0033089-&&-positive regulation of T cell differentiation in thymus-%%-GO:0042323-&&-negative regulation of circadian sleep/wake cycle, non-REM sleep-%%-GO:0046111-&&-xanthine biosynthetic process-%%-GO:0043101-&&-purine-containing compound salvage|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0060205-&&-cytoplasmic vesicle lumen-%%-GO:0030054-&&-cell junction-%%-GO:0009986-&&-cell surface-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004000-&&-adenosine deaminase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001883-&&-purine nucleoside binding	G:9606:ADA	ADA	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa00230-&&-Purine metabolism	ADA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADA	0.36753721	0.10833333	16	4	FALSE	ADA	ADA	164.75	0	16	0	0.71319784	FALSE	0	ADA	56998	0.08890465
792165	taxon:9606	2.98030566	1.74E-04	182495	1902	adenylate cyclase activating polypeptide 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0002865-&&-negative regulation of acute inflammatory response to antigenic stimulus-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0002878-&&-negative regulation of acute inflammatory response to non-antigenic stimulus-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0010579-&&-positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway-%%-GO:0070445-&&-regulation of oligodendrocyte progenitor proliferation-%%-GO:0071651-&&-positive regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0045471-&&-response to ethanol-%%-GO:0043267-&&-negative regulation of potassium ion transport-%%-GO:0007565-&&-female pregnancy-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0042594-&&-response to starvation-%%-GO:0090274-&&-positive regulation of somatostatin secretion-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0001662-&&-behavioral fear response-%%-GO:0031175-&&-neuron projection development-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001821-&&-histamine secretion-%%-GO:0060078-&&-regulation of postsynaptic membrane potential-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0010656-&&-negative regulation of muscle cell apoptotic process-%%-GO:0021983-&&-pituitary gland development-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005615-&&-extracellular space-%%-GO:0043195-&&-terminal bouton-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0051428-&&-peptide hormone receptor binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0031858-&&-pituitary adenylate cyclase-activating polypeptide receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0016521-&&-pituitary adenylate cyclase activating polypeptide activity-%%-GO:0005184-&&-neuropeptide hormone activity	G:9606:ADCYAP1			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04713-&&-Circadian entrainment-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	ADCYAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADCYAP1	0.33553605	0.04166667	16	4	FALSE	ADCYAP1	ADCYAP1	38.5	0	16	0	0.66994906	FALSE	0	ADCYAP1	145126	0.07544821
792262	taxon:9606	2.78021112	6.62E-06	165940	1902	myocardin	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0051152-&&-positive regulation of smooth muscle cell differentiation-%%-GO:0035051-&&-cardiocyte differentiation-%%-GO:1900222-&&-negative regulation of beta-amyloid clearance-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001666-&&-response to hypoxia-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0048286-&&-lung alveolus development-%%-GO:1900239-&&-regulation of phenotypic switching-%%-GO:0060065-&&-uterus development-%%-GO:0003257-&&-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0055007-&&-cardiac muscle cell differentiation-%%-GO:2001015-&&-negative regulation of skeletal muscle cell differentiation-%%-GO:0035886-&&-vascular smooth muscle cell differentiation-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0051150-&&-regulation of smooth muscle cell differentiation-%%-GO:2000724-&&-positive regulation of cardiac vascular smooth muscle cell differentiation-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0035065-&&-regulation of histone acetylation-%%-GO:1904753-&&-negative regulation of vascular associated smooth muscle cell migration-%%-GO:0043954-&&-cellular component maintenance-%%-GO:0055012-&&-ventricular cardiac muscle cell differentiation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045661-&&-regulation of myoblast differentiation-%%-GO:0060157-&&-urinary bladder development-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0001560-&&-regulation of cell growth by extracellular stimulus-%%-GO:0048565-&&-digestive tract development-%%-GO:2000721-&&-positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation-%%-GO:0097070-&&-ductus arteriosus closure-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:2000587-&&-negative regulation of platelet-derived growth factor receptor-beta signaling pathway-%%-GO:0003231-&&-cardiac ventricle development|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0070412-&&-R-SMAD binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0001076-&&-transcription factor activity, RNA polymerase II transcription factor binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000987-&&-core promoter proximal region sequence-specific DNA binding	G:9606:MYOCD				MYOCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYOCD	0.35968491	0.27472527	16	4	FALSE	MYOCD	MYOCD	165.7857143	0	15	0	0.70329815	FALSE	1	MYOCD	11212	0.10945461
792282	taxon:9606	2.87458642	4.30E-05	182292	1902	cadherin 13	gene	biological_process-&-1&-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0051668-&&-localization within membrane-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0055096-&&-low-density lipoprotein particle mediated signaling-%%-GO:0000278-&&-mitotic cell cycle-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0030100-&&-regulation of endocytosis-%%-GO:0034332-&&-adherens junction organization-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0016339-&&-calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005925-&&-focal adhesion-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005901-&&-caveola-%%-GO:0043005-&&-neuron projection-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0071813-&&-lipoprotein particle binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0055100-&&-adiponectin binding	G:9606:CDH13				CDH13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDH13	0.34787613	0.02197802	16	4	FALSE	CDH13	CDH13	94.21428571	0	15	0	0.68756893	FALSE	1	CDH13	48608	0.09543266
792319	taxon:9606	2.84638412	3.91E-05	182242	1902	centrin 3	gene	biological_process-&-1&-GO:0007098-&&-centrosome cycle-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005813-&&-centrosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:CETN3				CETN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CETN3	0.35132293	0.03333333	16	4	FALSE	CETN3	CETN3	89.5	0	16	0	0.69226931	FALSE	0	CETN3	27370	0.0778922
792340	taxon:9606	2.79738459	3.09E-05	165822	1902	retinol dehydrogenase 13	gene	biological_process-&-1&-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0009644-&&-response to high light intensity-%%-GO:0042572-&&-retinol metabolic process-%%-GO:0010842-&&-retina layer formation-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0052650-&&-NADP-retinol dehydrogenase activity	G:9606:RDH13				RDH13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RDH13	0.35747677	0.1	16	4	FALSE	RDH13	RDH13	117	0	16	0	0.7004359	FALSE	0	RDH13	28390	0.08136792
792373	taxon:9606	2.71907988	1.33E-05	165748	1902	SH2 domain containing 1B	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0002366-&&-leukocyte activation involved in immune response-%%-GO:0050776-&&-regulation of immune response-%%-GO:0002250-&&-adaptive immune response-%%-GO:0002717-&&-positive regulation of natural killer cell mediated immunity-%%-GO:0045089-&&-positive regulation of innate immune response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding	G:9606:SH2D1B			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity	SH2D1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D1B	0.36777147	0.18333333	16	4	FALSE	SH2D1B	SH2D1B	182.1875	0	16	0	0.71348669	FALSE	0	SH2D1B	21534	0.0979021
792379	taxon:9606	2.87915551	3.69E-06	182125	1902	carboxypeptidase M	gene	biological_process-&-1&-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0016485-&&-protein processing-%%-GO:0006518-&&-peptide metabolic process-%%-GO:0009653-&&-anatomical structure morphogenesis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004181-&&-metallocarboxypeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004180-&&-carboxypeptidase activity	G:9606:CPM				CPM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPM	0.34732407	0.31666667	16	4	FALSE	CPM	CPM	124.75	0	16	0	0.68680742	FALSE	0	CPM	6934	0.13167283
792422	taxon:9606	2.70048842	2.22E-05	182051	1902	casein kinase 1 gamma 2	gene	biological_process-&-1&-GO:0030148-&&-sphingolipid biosynthetic process-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006897-&&-endocytosis-%%-GO:0016055-&&-Wnt signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0042277-&&-peptide binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0051219-&&-phosphoprotein binding	G:9606:CSNK1G2			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway	CSNK1G2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1G2	0.37030338	0.10833333	16	5	FALSE	CSNK1G2	CSNK1G2	154.9375	0	16	0	0.71658526	FALSE	0	CSNK1G2	28064	0.07788897
792436	taxon:9606	2.67260123	9.47E-06	149257	1902	translocase of inner mitochondrial membrane 23	gene	biological_process-&-1&-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0030150-&&-protein import into mitochondrial matrix|cellular_component-&-1&-GO:0005744-&&-mitochondrial inner membrane presequence translocase complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0031305-&&-integral component of mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0015450-&&-P-P-bond-hydrolysis-driven protein transmembrane transporter activity-%%-GO:0015266-&&-protein channel activity	G:9606:TIMM23				TIMM23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMM23	0.37416731	0.19166667	16	4	FALSE	TIMM23	TIMM23	209.875	0	16	0	0.72123313	FALSE	0	TIMM23	24342	0.09786031
792492	taxon:9606	2.78509532	1.32E-05	165533	1902	oxysterol binding protein like 10	gene	biological_process-&-1&-GO:0015914-&&-phospholipid transport-%%-GO:0036150-&&-phosphatidylserine acyl-chain remodeling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005548-&&-phospholipid transporter activity-%%-GO:0001786-&&-phosphatidylserine binding	G:9606:OSBPL10				OSBPL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSBPL10	0.35905414	0.11666667	16	4	FALSE	OSBPL10	OSBPL10	128.25	0	16	0	0.70248411	FALSE	0	OSBPL10	17398	0.08676321
792493	taxon:9606	2.66614148	1.76E-05	165534	1902	oxysterol binding protein like 9	gene	biological_process-&-1&-GO:0015918-&&-sterol transport-%%-GO:0006699-&&-bile acid biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031902-&&-late endosome membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0015248-&&-sterol transporter activity-%%-GO:0008289-&&-lipid binding	G:9606:OSBPL9				OSBPL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSBPL9	0.37507387	0.1	16	4	FALSE	OSBPL9	OSBPL9	186.5625	0	16	0	0.72230975	FALSE	0	OSBPL9	25422	0.08364218
792501	taxon:9606	2.74318576	1.00E-04	181903	1902	carbonic anhydrase 2	gene	biological_process-&-1&-GO:0032849-&&-positive regulation of cellular pH reduction-%%-GO:2001225-&&-regulation of chloride transport-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0044070-&&-regulation of anion transport-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0043627-&&-response to estrogen-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0009268-&&-response to pH-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0010043-&&-response to zinc ion-%%-GO:2001150-&&-positive regulation of dipeptide transmembrane transport-%%-GO:0001822-&&-kidney development-%%-GO:0015670-&&-carbon dioxide transport-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0046903-&&-secretion-%%-GO:0048545-&&-response to steroid hormone|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0043209-&&-myelin sheath-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0045177-&&-apical part of cell|molecular_function-&-1&-GO:0004064-&&-arylesterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004089-&&-carbonate dehydratase activity	G:9606:CA2	CA2	TRUE	KEGG-&-1&-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04971-&&-Gastric acid secretion-%%-hsa00910-&&-Nitrogen metabolism-%%-hsa04976-&&-Bile secretion-%%-hsa04972-&&-Pancreatic secretion	CA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CA2	0.36453966	0.16666667	16	4	FALSE	CA2	CA2	173.75	0	16	0	0.70946904	FALSE	0	CA2	116538	0.09977691
792510	taxon:9606	2.80983142	9.42E-06	165496	1902	F-box protein 17	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0001948-&&-glycoprotein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO17				FBXO17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO17	0.35589324	0.325	16	4	FALSE	FBXO17	FBXO17	165.375	0	16	0	0.69836143	FALSE	0	FBXO17	12526	0.12373501
792530	taxon:9606	2.88687569	1.93E-05	181845	1902	calpain 3	gene	biological_process-&-1&-GO:0051592-&&-response to calcium ion-%%-GO:0014718-&&-positive regulation of satellite cell activation involved in skeletal muscle regeneration-%%-GO:0007165-&&-signal transduction-%%-GO:0043122-&&-regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0030239-&&-myofibril assembly-%%-GO:0006461-&&-protein complex assembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045214-&&-sarcomere organization-%%-GO:0071472-&&-cellular response to salt stress-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0070315-&&-G1 to G0 transition involved in cell differentiation-%%-GO:2001015-&&-negative regulation of skeletal muscle cell differentiation-%%-GO:0006915-&&-apoptotic process-%%-GO:0097264-&&-self proteolysis-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007517-&&-muscle organ development-%%-GO:0045661-&&-regulation of myoblast differentiation-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0014850-&&-response to muscle activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006508-&&-proteolysis-%%-GO:0061061-&&-muscle structure development-%%-GO:0072657-&&-protein localization to membrane|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0030016-&&-myofibril-%%-GO:0005829-&&-cytosol-%%-GO:0030018-&&-Z disc-%%-GO:0030315-&&-T-tubule-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0031432-&&-titin binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0031402-&&-sodium ion binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0055103-&&-ligase regulator activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0004871-&&-signal transducer activity-%%-GO:0008234-&&-cysteine-type peptidase activity	G:9606:CAPN3				CAPN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPN3	0.34639524	0.0989011	16	4	FALSE	CAPN3	CAPN3	82.14285714	0	15	0	0.68552072	FALSE	1	CAPN3	18098	0.09044988
792557	taxon:9606	2.77233339	2.00E-05	181819	1902	caveolin 3	gene	biological_process-&-1&-GO:1901019-&&-regulation of calcium ion transmembrane transporter activity-%%-GO:0090279-&&-regulation of calcium ion import-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0035995-&&-detection of muscle stretch-%%-GO:0010831-&&-positive regulation of myotube differentiation-%%-GO:0001778-&&-plasma membrane repair-%%-GO:0008104-&&-protein localization-%%-GO:0006897-&&-endocytosis-%%-GO:1901380-&&-negative regulation of potassium ion transmembrane transport-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:0060373-&&-regulation of ventricular cardiac muscle cell membrane depolarization-%%-GO:1900744-&&-regulation of p38MAPK cascade-%%-GO:1900825-&&-regulation of membrane depolarization during cardiac muscle cell action potential-%%-GO:1900826-&&-negative regulation of membrane depolarization during cardiac muscle cell action potential-%%-GO:0038009-&&-regulation of signal transduction by receptor internalization-%%-GO:0007015-&&-actin filament organization-%%-GO:0031116-&&-positive regulation of microtubule polymerization-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0043409-&&-negative regulation of MAPK cascade-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0033292-&&-T-tubule organization-%%-GO:0007517-&&-muscle organ development-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0010614-&&-negative regulation of cardiac muscle hypertrophy-%%-GO:0051926-&&-negative regulation of calcium ion transport-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0031579-&&-membrane raft organization-%%-GO:0051394-&&-regulation of nerve growth factor receptor activity-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0007520-&&-myoblast fusion-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0030154-&&-cell differentiation-%%-GO:0016049-&&-cell growth-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0007009-&&-plasma membrane organization-%%-GO:0051647-&&-nucleus localization-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:2001288-&&-positive regulation of caveolin-mediated endocytosis-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:0055013-&&-cardiac muscle cell development-%%-GO:0060299-&&-negative regulation of sarcomere organization-%%-GO:0070836-&&-caveola assembly-%%-GO:0014819-&&-regulation of skeletal muscle contraction-%%-GO:0045792-&&-negative regulation of cell size-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:1901017-&&-negative regulation of potassium ion transmembrane transporter activity-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity-%%-GO:0006936-&&-muscle contraction-%%-GO:0051896-&&-regulation of protein kinase B signaling-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0061052-&&-negative regulation of cell growth involved in cardiac muscle cell development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0009986-&&-cell surface-%%-GO:0042383-&&-sarcolemma-%%-GO:0014704-&&-intercalated disc-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030315-&&-T-tubule-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031982-&&-vesicle-%%-GO:0005901-&&-caveola-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0030018-&&-Z disc-%%-GO:0045121-&&-membrane raft-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0017080-&&-sodium channel regulator activity-%%-GO:0071253-&&-connexin binding-%%-GO:0005515-&&-protein binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0050998-&&-nitric-oxide synthase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0019870-&&-potassium channel inhibitor activity-%%-GO:0032403-&&-protein complex binding	G:9606:CAV3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells	CAV3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAV3	0.36070698	0.1	16	4	FALSE	CAV3	CAV3	127.9375	0	16	0	0.7046111	FALSE	0	CAV3	24416	0.08216699
792581	taxon:9606	2.80951631	1.25E-05	181769	1902	CD5 molecule	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0008037-&&-cell recognition-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:CD5			KEGG-&-1&-hsa04640-&&-Hematopoietic cell lineage	CD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD5	0.35593315	0.23333333	16	5	FALSE	CD5	CD5	133.875	0	16	0	0.69841395	FALSE	0	CD5	13312	0.10245587
792639	taxon:9606	2.88466992	6.84E-05	181664	1902	CD28 molecule	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0045070-&&-positive regulation of viral genome replication-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0045589-&&-regulation of regulatory T cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006959-&&-humoral immune response-%%-GO:0042089-&&-cytokine biosynthetic process-%%-GO:0045066-&&-regulatory T cell differentiation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:0002863-&&-positive regulation of inflammatory response to antigenic stimulus-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0031295-&&-T cell costimulation-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0051897-&&-positive regulation of protein kinase B signaling|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0098636-&&-protein complex involved in cell adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0015026-&&-coreceptor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:CD28	CD28	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05330-&&-Allograft rejection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05323-&&-Rheumatoid arthritis	CD28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD28	0.34666011	0.25833333	16	5	FALSE	CD28	CD28	107.625	0	16	0	0.68588835	FALSE	0	CD28	93506	0.10985429
792659	taxon:9606	2.78840397	1.38E-05	165234	1902	threonyl-tRNA synthetase like 2	gene	biological_process-&-1&-GO:0006435-&&-threonyl-tRNA aminoacylation-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004829-&&-threonine-tRNA ligase activity-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TARSL2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	TARSL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARSL2	0.35862809	0.1	16	4	FALSE	TARSL2	TARSL2	122.9375	0	16	0	0.70193267	FALSE	0	TARSL2	17726	0.08302302
792677	taxon:9606	2.89097211	5.99E-06	181573	1902	D-box binding PAR bZIP transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007623-&&-circadian rhythm-%%-GO:0001889-&&-liver development-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:DBP				DBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBP	0.34590441	0.52747253	16	5	FALSE	DBP	DBP	104.1428571	0	15	0	0.68483798	FALSE	1	DBP	8648	0.10695933
792714	taxon:9606	2.85804317	7.44E-06	165125	1902	chromosome 19 open reading frame 70	gene	biological_process-&-1&-GO:0042407-&&-cristae formation|cellular_component-&-1&-GO:0044284-&&-mitochondrial crista junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0061617-&&-MICOS complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion	G:9606:C19orf70				C19orf70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C19orf70	0.34988975	0.075	16	4	FALSE	C19orf70	C19orf70	90.5	0	16	0	0.69032614	FALSE	0	C19orf70	9758	0.08415033
792715	taxon:9606	2.64676225	2.17E-05	181510	1902	24-dehydrocholesterol reductase	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0061024-&&-membrane organization-%%-GO:0030539-&&-male genitalia development-%%-GO:0043588-&&-skin development-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0033490-&&-cholesterol biosynthetic process via lathosterol-%%-GO:0006695-&&-cholesterol biosynthetic process-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0033489-&&-cholesterol biosynthetic process via desmosterol-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0006915-&&-apoptotic process-%%-GO:0008104-&&-protein localization-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009725-&&-response to hormone-%%-GO:0031639-&&-plasminogen activation-%%-GO:0009888-&&-tissue development-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding-%%-GO:0050614-&&-delta24-sterol reductase activity-%%-GO:0000246-&&-delta24(24-1) sterol reductase activity-%%-GO:0016628-&&-oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor-%%-GO:0019899-&&-enzyme binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0016614-&&-oxidoreductase activity, acting on CH-OH group of donors	G:9606:DHCR24			KEGG-&-1&-hsa00100-&&-Steroid biosynthesis-%%-hsa01100-&&-Metabolic pathways	DHCR24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHCR24	0.37782011	0.11666667	16	4	FALSE	DHCR24	DHCR24	228.0625	0	16	0	0.72553963	FALSE	0	DHCR24	37786	0.09911918
792778	taxon:9606	2.71687411	1.05E-04	181385	1902	dopamine receptor D4	gene	biological_process-&-1&-GO:0001662-&&-behavioral fear response-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:1901386-&&-negative regulation of voltage-gated calcium channel activity-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0007195-&&-adenylate cyclase-inhibiting dopamine receptor signaling pathway-%%-GO:0060080-&&-inhibitory postsynaptic potential-%%-GO:0042053-&&-regulation of dopamine metabolic process-%%-GO:0033674-&&-positive regulation of kinase activity-%%-GO:0050709-&&-negative regulation of protein secretion-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0048149-&&-behavioral response to ethanol-%%-GO:0051586-&&-positive regulation of dopamine uptake involved in synaptic transmission-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0042417-&&-dopamine metabolic process-%%-GO:0042596-&&-fear response-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0001975-&&-response to amphetamine-%%-GO:0034776-&&-response to histamine-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0035176-&&-social behavior-%%-GO:0032417-&&-positive regulation of sodium:proton antiporter activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0098794-&&-postsynapse-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001591-&&-dopamine neurotransmitter receptor activity, coupled via Gi/Go-%%-GO:0004952-&&-dopamine neurotransmitter receptor activity-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0008144-&&-drug binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0035240-&&-dopamine binding	G:9606:DRD4			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	DRD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DRD4	0.36807005	0.20879121	16	4	FALSE	DRD4	DRD4	203.8571429	0	15	0	0.71385431	FALSE	1	DRD4	126404	0.10824351
792834	taxon:9606	2.77910824	7.21E-06	181288	1902	EPH receptor B1	gene	biological_process-&-1&-GO:0022008-&&-neurogenesis-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0060996-&&-dendritic spine development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0021631-&&-optic nerve morphogenesis-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0061351-&&-neural precursor cell proliferation-%%-GO:0007411-&&-axon guidance-%%-GO:0021952-&&-central nervous system projection neuron axonogenesis-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:1901214-&&-regulation of neuron death|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0032433-&&-filopodium tip-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0045121-&&-membrane raft-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005005-&&-transmembrane-ephrin receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0008046-&&-axon guidance receptor activity-%%-GO:0005524-&&-ATP binding	G:9606:EPHB1			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHB1	0.35982765	0.21978022	16	4	FALSE	EPHB1	EPHB1	156.1428571	0	15	0	0.70348196	FALSE	1	EPHB1	11180	0.1030592
792839	taxon:9606	2.9056247	1.10E-05	164896	1902	transport and golgi organization 2 homolog	gene	cellular_component-&-1&-GO:0005794-&&-Golgi apparatus	G:9606:TANGO2				TANGO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TANGO2	0.34416007	0.125	16	4	FALSE	TANGO2	TANGO2	73.875	0	16	0	0.68239588	FALSE	0	TANGO2	11302	0.09195313
792840	taxon:9606	2.88167638	2.12E-05	181283	1902	epoxide hydrolase 1	gene	biological_process-&-1&-GO:0009636-&&-response to toxic substance-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0019439-&&-aromatic compound catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0033961-&&-cis-stilbene-oxide hydrolase activity-%%-GO:0004301-&&-epoxide hydrolase activity	G:9606:EPHX1	EPHX1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa04976-&&-Bile secretion-%%-hsa05204-&&-Chemical carcinogenesis	EPHX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHX1	0.34702023	0.00833333	16	5	FALSE	EPHX1	EPHX1	78.9375	0	16	0	0.68638727	FALSE	0	EPHX1	23162	0.07441611
792882	taxon:9606	2.91098157	1.82E-05	181225	1902	exostosin glycosyltransferase 2	gene	biological_process-&-1&-GO:0001503-&&-ossification-%%-GO:0006486-&&-protein glycosylation-%%-GO:0001707-&&-mesoderm formation-%%-GO:0007165-&&-signal transduction-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0015012-&&-heparan sulfate proteoglycan biosynthetic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0015014-&&-heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process-%%-GO:0033692-&&-cellular polysaccharide biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0043541-&&-UDP-N-acetylglucosamine transferase complex-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0050508-&&-glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0008375-&&-acetylglucosaminyltransferase activity-%%-GO:0015020-&&-glucuronosyltransferase activity-%%-GO:0050509-&&-N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0042328-&&-heparan sulfate N-acetylglucosaminyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0016757-&&-transferase activity, transferring glycosyl groups	G:9606:EXT2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	EXT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXT2	0.34352674	0.05494505	16	5	FALSE	EXT2	EXT2	95.35714286	0	15	0	0.68150307	FALSE	1	EXT2	17224	0.11792369
792982	taxon:9606	2.75011817	3.97E-06	181044	1902	Fli-1 proto-oncogene, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0007599-&&-hemostasis-%%-GO:0008015-&&-blood circulation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding	G:9606:FLI1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	FLI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLI1	0.36362074	0.175	16	4	FALSE	FLI1	FLI1	164.125	0	16	0	0.70831364	FALSE	0	FLI1	10206	0.09696746
793002	taxon:9606	2.76477076	3.31E-05	164626	1902	PPARG coactivator 1 beta	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0060346-&&-bone trabecula formation-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0045780-&&-positive regulation of bone resorption-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0001503-&&-ossification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0006390-&&-transcription from mitochondrial promoter-%%-GO:0051591-&&-response to cAMP-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0016592-&&-mediator complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0030546-&&-receptor activator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0000166-&&-nucleotide binding-%%-GO:0030331-&&-estrogen receptor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0050682-&&-AF-2 domain binding-%%-GO:0001104-&&-RNA polymerase II transcription cofactor activity	G:9606:PPARGC1B			KEGG-&-1&-hsa04931-&&-Insulin resistance	PPARGC1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPARGC1B	0.36169364	0.09166667	16	5	FALSE	PPARGC1B	PPARGC1B	139.5	0	16	0	0.70587154	FALSE	0	PPARGC1B	33324	0.08757084
793169	taxon:9606	2.8589885	9.49E-06	180601	1902	G protein subunit gamma 5	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0072513-&&-positive regulation of secondary heart field cardioblast proliferation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005515-&&-protein binding	G:9606:GNG5			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNG5	0.34977405	0.15	16	4	FALSE	GNG5	GNG5	94.125	0	16	0	0.69016858	FALSE	0	GNG5	14920	0.08825259
793209	taxon:9606	2.83850638	1.25E-05	180527	1902	hydroxysteroid 17-beta dehydrogenase 3	gene	biological_process-&-1&-GO:0061370-&&-testosterone biosynthetic process-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0030539-&&-male genitalia development-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0047045-&&-testosterone 17-beta-dehydrogenase (NADP+) activity-%%-GO:0047035-&&-testosterone dehydrogenase (NAD+) activity	G:9606:HSD17B3	HSD17B3	TRUE	KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways	HSD17B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B3	0.35229796	0.04166667	16	4	FALSE	HSD17B3	HSD17B3	104.375	0	16	0	0.69358227	FALSE	0	HSD17B3	15696	0.08785926
793287	taxon:9606	2.73325981	1.64E-05	163990	1902	synaptotagmin 6	gene	biological_process-&-1&-GO:0060478-&&-acrosomal vesicle exocytosis-%%-GO:0048791-&&-calcium ion-regulated exocytosis of neurotransmitter-%%-GO:0017158-&&-regulation of calcium ion-dependent exocytosis-%%-GO:0006906-&&-vesicle fusion|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0019898-&&-extrinsic component of membrane|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0019905-&&-syntaxin binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding	G:9606:SYT6				SYT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYT6	0.3658635	0.04395604	16	5	FALSE	SYT6	SYT6	161.3571429	0	15	0	0.71112337	FALSE	1	SYT6	23626	0.09063456
787042	taxon:9606	2.7994328	2.77E-05	180178	1902	homeobox C8	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048705-&&-skeletal system morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXC8				HOXC8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXC8	0.35721522	0.19047619	15	4	FALSE	HOXC8	HOXC8	156.6666667	0	15	0	0.70009453	FALSE	0	HOXC8	29216	0.11233859
787051	taxon:9606	2.90625492	2.83E-05	180160	1902	iduronate 2-sulfatase	gene	biological_process-&-1&-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0006027-&&-glycosaminoglycan catabolic process|cellular_component-&-1&-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004423-&&-iduronate-2-sulfatase activity	G:9606:IDS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04142-&&-Lysosome-%%-hsa00531-&&-Glycosaminoglycan degradation	IDS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDS	0.34408544	0.05714286	15	4	FALSE	IDS	IDS	69.26666667	0	15	0	0.68229085	FALSE	0	IDS	23220	0.07485507
787079	taxon:9606	3.05073263	7.10E-05	180109	1902	insulin like growth factor binding protein 7	gene	biological_process-&-1&-GO:0050810-&&-regulation of steroid biosynthetic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0009408-&&-response to heat-%%-GO:0051414-&&-response to cortisol-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007566-&&-embryo implantation-%%-GO:0007155-&&-cell adhesion-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0032870-&&-cellular response to hormone stimulus|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005520-&&-insulin-like growth factor binding	G:9606:IGFBP7				IGFBP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP7	0.32779012	0.01904762	15	5	FALSE	IGFBP7	IGFBP7	28.66666667	0	15	0	0.65821123	FALSE	0	IGFBP7	65802	0.07980952
787111	taxon:9606	2.93146368	1.29E-04	180040	1902	C-X-C motif chemokine receptor 1	gene	biological_process-&-1&-GO:0031623-&&-receptor internalization-%%-GO:0006935-&&-chemotaxis-%%-GO:0038112-&&-interleukin-8-mediated signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0006954-&&-inflammatory response-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0070098-&&-chemokine-mediated signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0004950-&&-chemokine receptor activity-%%-GO:0019959-&&-interleukin-8 binding-%%-GO:0004918-&&-interleukin-8 receptor activity	G:9606:CXCR1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCR1	0.34112652	0.12820513	15	4	FALSE	CXCR1	CXCR1	58.38461538	0	14	0	0.67808939	FALSE	1	CXCR1	170502	0.089311
787211	taxon:9606	2.89932251	1.32E-05	179857	1902	matrilin 2	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0001764-&&-neuron migration-%%-GO:0031104-&&-dendrite regeneration-%%-GO:0048678-&&-response to axon injury-%%-GO:0008150-&&-biological_process-%%-GO:0008347-&&-glial cell migration|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MATN2				MATN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MATN2	0.34490816	0.12820513	15	5	FALSE	MATN2	MATN2	87.38461538	0	14	0	0.68344625	FALSE	1	MATN2	9778	0.08946746
787219	taxon:9606	2.87238065	1.82E-05	179842	1902	melanoma cell adhesion molecule	gene	biological_process-&-1&-GO:0061042-&&-vascular wound healing-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0003094-&&-glomerular filtration-%%-GO:0001525-&&-angiogenesis-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane	G:9606:MCAM				MCAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCAM	0.34814327	0.06666667	15	4	FALSE	MCAM	MCAM	90.53333333	0	15	0	0.68793656	FALSE	0	MCAM	19282	0.08666667
787633	taxon:9606	2.74287065	3.47E-05	179058	1902	nephroblastoma overexpressed	gene	biological_process-&-1&-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0071603-&&-endothelial cell-cell adhesion-%%-GO:1904057-&&-negative regulation of sensory perception of pain-%%-GO:0035767-&&-endothelial cell chemotaxis-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0061484-&&-hematopoietic stem cell homeostasis-%%-GO:0042347-&&-negative regulation of NF-kappaB import into nucleus-%%-GO:0010761-&&-fibroblast migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0044342-&&-type B pancreatic cell proliferation-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0010468-&&-regulation of gene expression-%%-GO:1902731-&&-negative regulation of chondrocyte proliferation-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0048659-&&-smooth muscle cell proliferation-%%-GO:1990523-&&-bone regeneration-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0060392-&&-negative regulation of SMAD protein import into nucleus-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0090027-&&-negative regulation of monocyte chemotaxis|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005921-&&-gap junction-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005112-&&-Notch binding-%%-GO:0005520-&&-insulin-like growth factor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005178-&&-integrin binding	G:9606:NOV				NOV	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOV	0.36458154	0.06666667	15	4	FALSE	NOV	NOV	166.4	0	15	0	0.70952156	FALSE	0	NOV	38940	0.09764706
787662	taxon:9606	2.64991334	5.04E-06	178996	1902	nuclear VCP-like	gene	biological_process-&-1&-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0042254-&&-ribosome biogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005697-&&-telomerase holoenzyme complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:1990275-&&-preribosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:NVL			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	NVL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NVL	0.37737083	0.33333333	15	4	FALSE	NVL	NVL	311	0	15	0	0.72501444	FALSE	0	NVL	12184	0.13425446
787666	taxon:9606	3.0316685	1.42E-05	178988	1902	serpin family E member 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0014067-&&-negative regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0010766-&&-negative regulation of sodium ion transport-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0060384-&&-innervation-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0050974-&&-detection of mechanical stimulus involved in sensory perception-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0010757-&&-negative regulation of plasminogen activation-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0048505-&&-regulation of timing of cell differentiation-%%-GO:0021683-&&-cerebellar granular layer morphogenesis-%%-GO:0032940-&&-secretion by cell-%%-GO:0061108-&&-seminal vesicle epithelium development-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0033363-&&-secretory granule organization-%%-GO:0042628-&&-mating plug formation|cellular_component-&-1&-GO:0031091-&&-platelet alpha granule-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0031594-&&-neuromuscular junction-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008201-&&-heparin binding	G:9606:SERPINE2				SERPINE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINE2	0.32985137	0.01904762	15	5	FALSE	SERPINE2	SERPINE2	37.53333333	0	15	0	0.66138858	FALSE	0	SERPINE2	10522	0.0855814
787693	taxon:9606	2.91113912	1.09E-05	178932	1902	phospholipase C beta 2	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0050913-&&-sensory perception of bitter taste-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0006644-&&-phospholipid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0004629-&&-phospholipase C activity-%%-GO:0005509-&&-calcium ion binding	G:9606:PLCB2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04720-&&-Long-term potentiation-%%-hsa04934-&&-Cushing syndrome-%%-hsa04540-&&-Gap junction-%%-hsa04713-&&-Circadian entrainment-%%-hsa05016-&&-Huntington disease-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00562-&&-Inositol phosphate metabolism-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04916-&&-Melanogenesis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04924-&&-Renin secretion-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04970-&&-Salivary secretion	PLCB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCB2	0.34350815	0.08974359	15	4	FALSE	PLCB2	PLCB2	74.46153846	0	14	0	0.68147681	FALSE	1	PLCB2	10062	0.09308176
787748	taxon:9606	2.7447613	3.87E-06	162460	1902	jumonji domain containing 1C	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000785-&&-chromatin-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:JMJD1C			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	JMJD1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JMJD1C	0.36433041	0.12380952	15	4	FALSE	JMJD1C	JMJD1C	166.1333333	0	15	0	0.70920645	FALSE	0	JMJD1C	10930	0.0967366
787833	taxon:9606	2.93603277	5.08E-06	162352	1902	regulatory factor X6	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0003310-&&-pancreatic A cell differentiation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0003309-&&-type B pancreatic cell differentiation-%%-GO:0090104-&&-pancreatic epsilon cell differentiation-%%-GO:0003311-&&-pancreatic D cell differentiation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:RFX6			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young	RFX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFX6	0.34059565	0.0952381	15	5	FALSE	RFX6	RFX6	64.66666667	0	15	0	0.67732787	FALSE	0	RFX6	7058	0.0870822
787854	taxon:9606	3.04443044	7.12E-05	178714	1902	protein C, inactivator of coagulation factors Va and VIIIa	gene	biological_process-&-1&-GO:1903142-&&-positive regulation of establishment of endothelial barrier-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006465-&&-signal peptide processing-%%-GO:0050819-&&-negative regulation of coagulation-%%-GO:0044537-&&-regulation of circulating fibrinogen levels-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0006508-&&-proteolysis-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001889-&&-liver development|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:PROC			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	PROC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PROC	0.32846866	0.14102564	15	5	FALSE	PROC	PROC	37.46153846	0	14	0	0.65926159	FALSE	1	PROC	68182	0.09265298
787934	taxon:9606	2.82731999	4.80E-05	178560	1902	oncostatin M	gene	biological_process-&-1&-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0009408-&&-response to heat-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0038165-&&-oncostatin-M-mediated signaling pathway-%%-GO:0042503-&&-tyrosine phosphorylation of Stat3 protein-%%-GO:0042508-&&-tyrosine phosphorylation of Stat1 protein-%%-GO:0006955-&&-immune response-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0040008-&&-regulation of growth-%%-GO:0042506-&&-tyrosine phosphorylation of Stat5 protein-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008283-&&-cell proliferation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0046888-&&-negative regulation of hormone secretion-%%-GO:0007275-&&-multicellular organism development-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045835-&&-negative regulation of meiotic nuclear division-%%-GO:0048266-&&-behavioral response to pain|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005147-&&-oncostatin-M receptor binding	G:9606:OSM			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	OSM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSM	0.35369184	0.08571429	15	5	FALSE	OSM	OSM	95.13333333	0	15	0	0.69544667	FALSE	0	OSM	33680	0.0745283
787955	taxon:9606	2.83614306	2.40E-06	178518	1902	p21 (RAC1) activated kinase 3	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0050808-&&-synapse organization-%%-GO:0007409-&&-axonogenesis-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0016358-&&-dendrite development-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0061003-&&-positive regulation of dendritic spine morphogenesis-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:PAK3			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	PAK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK3	0.35259152	0.20512821	15	4	FALSE	PAK3	PAK3	124.9230769	0	14	0	0.69397616	FALSE	1	PAK3	5554	0.10421215
788003	taxon:9606	2.69970065	4.00E-05	178423	1902	PDZ domain containing 1	gene	biological_process-&-1&-GO:0044070-&&-regulation of anion transport-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0008283-&&-cell proliferation-%%-GO:0015879-&&-carnitine transport-%%-GO:0015893-&&-drug transport-%%-GO:0034767-&&-positive regulation of ion transmembrane transport-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0031526-&&-brush border membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031528-&&-microvillus membrane|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0005124-&&-scavenger receptor binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:PDZK1				PDZK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDZK1	0.37041144	0.16190476	15	5	FALSE	PDZK1	PDZK1	165.4	0	15	0	0.71671656	FALSE	0	PDZK1	31868	0.08361181
788205	taxon:9606	2.77217583	4.68E-06	178083	1902	retinol binding protein 1	gene	biological_process-&-1&-GO:0001523-&&-retinoid metabolic process-%%-GO:0006810-&&-transport-%%-GO:0002138-&&-retinoic acid biosynthetic process-%%-GO:0006776-&&-vitamin A metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016918-&&-retinal binding-%%-GO:0019841-&&-retinol binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005501-&&-retinoid binding	G:9606:RBP1				RBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBP1	0.36072748	0.39047619	15	5	FALSE	RBP1	RBP1	183.1333333	0	15	0	0.70463736	FALSE	0	RBP1	9656	0.11494975
788311	taxon:9606	2.7594139	2.33E-05	161520	1902	anaphase promoting complex subunit 1 pseudogene	gene		G:9606:LOC285074				LOC285074	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC285074	0.3623958	0.2	15	4	FALSE	LOC285074	LOC285074	129.1333333	0	15	0	0.70676435	FALSE	0	LOC285074	27154	0.07831715
788338	taxon:9606	2.89821963	6.80E-06	177848	1902	sodium channel epithelial 1 gamma subunit	gene	biological_process-&-1&-GO:0050891-&&-multicellular organismal water homeostasis-%%-GO:0007588-&&-excretion-%%-GO:0050896-&&-response to stimulus-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0055078-&&-sodium ion homeostasis-%%-GO:0050909-&&-sensory perception of taste|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0034706-&&-sodium channel complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0005216-&&-ion channel activity-%%-GO:0015280-&&-ligand-gated sodium channel activity-%%-GO:0005272-&&-sodium channel activity	G:9606:SCNN1G			KEGG-&-1&-hsa04742-&&-Taste transduction-%%-hsa04960-&&-Aldosterone-regulated sodium reabsorption	SCNN1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCNN1G	0.34503941	0.02564103	15	4	FALSE	SCNN1G	SCNN1G	85.69230769	0	14	0	0.68363006	FALSE	1	SCNN1G	8416	0.09860789
788522	taxon:9606	2.82164802	1.16E-05	177509	1902	UDP-N-acetylglucosamine pyrophosphorylase 1	gene	biological_process-&-1&-GO:0006048-&&-UDP-N-acetylglucosamine biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0003977-&&-UDP-N-acetylglucosamine diphosphorylase activity-%%-GO:0042802-&&-identical protein binding	G:9606:UAP1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	UAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UAP1	0.35440281	0.11538462	15	5	FALSE	UAP1	UAP1	132.8461539	0	14	0	0.696392	FALSE	1	UAP1	12578	0.10384917
788597	taxon:9606	2.79691193	9.08E-06	177368	1902	T-box 3	gene	biological_process-&-1&-GO:0009887-&&-animal organ morphogenesis-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0030539-&&-male genitalia development-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032275-&&-luteinizing hormone secretion-%%-GO:0030879-&&-mammary gland development-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0001568-&&-blood vessel development-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0060931-&&-sinoatrial node cell development-%%-GO:0007569-&&-cell aging-%%-GO:0090398-&&-cellular senescence-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0060596-&&-mammary placode formation-%%-GO:0003167-&&-atrioventricular bundle cell differentiation-%%-GO:0021761-&&-limbic system development-%%-GO:0001501-&&-skeletal system development-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0060021-&&-palate development-%%-GO:0035136-&&-forelimb morphogenesis-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0008595-&&-anterior/posterior axis specification, embryo-%%-GO:0060923-&&-cardiac muscle cell fate commitment-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0010159-&&-specification of animal organ position-%%-GO:0001947-&&-heart looping-%%-GO:0030540-&&-female genitalia development-%%-GO:2000648-&&-positive regulation of stem cell proliferation-%%-GO:0046884-&&-follicle-stimulating hormone secretion-%%-GO:0048332-&&-mesoderm morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:TBX3			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	TBX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBX3	0.35753718	0.16666667	15	5	FALSE	TBX3	TBX3	179.3846154	0	14	0	0.70051468	FALSE	1	TBX3	12360	0.12392867
788657	taxon:9606	2.95052781	2.44E-05	177240	1902	transforming growth factor beta receptor 3	gene	biological_process-&-1&-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0060389-&&-pathway-restricted SMAD protein phosphorylation-%%-GO:0016477-&&-cell migration-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0060318-&&-definitive erythrocyte differentiation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060021-&&-palate development-%%-GO:0060216-&&-definitive hemopoiesis-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0060347-&&-heart trabecula formation-%%-GO:0051271-&&-negative regulation of cellular component movement-%%-GO:0060939-&&-epicardium-derived cardiac fibroblast cell development-%%-GO:0003150-&&-muscular septum morphogenesis-%%-GO:0060038-&&-cardiac muscle cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0034699-&&-response to luteinizing hormone-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0006955-&&-immune response-%%-GO:0007181-&&-transforming growth factor beta receptor complex assembly-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0016049-&&-cell growth-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0001889-&&-liver development-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition-%%-GO:0032354-&&-response to follicle-stimulating hormone-%%-GO:0034695-&&-response to prostaglandin E-%%-GO:0060979-&&-vasculogenesis involved in coronary vascular morphogenesis|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043235-&&-receptor complex-%%-GO:0034673-&&-inhibin-betaglycan-ActRII complex-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0005114-&&-type II transforming growth factor beta receptor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0015026-&&-coreceptor activity-%%-GO:0048185-&&-activin binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0070123-&&-transforming growth factor beta receptor activity, type III	G:9606:TGFBR3	TGFBR3	TRUE		TGFBR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBR3	0.33892241	0.13333333	15	5	FALSE	TGFBR3	TGFBR3	52.33333333	0	15	0	0.67491203	FALSE	0	TGFBR3	17808	0.07817818
788700	taxon:9606	2.82542934	4.85E-06	177156	1902	tensin 1	gene	biological_process-&-1&-GO:0007044-&&-cell-substrate junction assembly-%%-GO:0010761-&&-fibroblast migration|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:TNS1				TNS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNS1	0.35392851	0.07692308	15	5	FALSE	TNS1	TNS1	135.9230769	0	14	0	0.69576178	FALSE	1	TNS1	9082	0.10880445
788730	taxon:9606	2.74271309	1.36E-05	177094	1902	trophinin	gene	biological_process-&-1&-GO:0007566-&&-embryo implantation-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0030308-&&-negative regulation of cell growth|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TRO				TRO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRO	0.36460248	0.07619048	15	4	FALSE	TRO	TRO	162	0	15	0	0.70954782	FALSE	0	TRO	20440	0.09422741
788797	taxon:9606	2.53158973	8.42E-06	127707	1902	BUB1B-PAK6 readthrough	gene		G:9606:BUB1B-PAK6			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	BUB1B-PAK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUB1B-PAK6	0.39500871	0.2	15	4	FALSE	BUB1B-PAK6	BUB1B-PAK6	322.6666667	0	15	0	0.74473505	FALSE	0	BUB1B-PAK6	28424	0.10714048
788853	taxon:9606	2.81377029	1.68E-05	176751	1902	UV radiation resistance associated	gene	biological_process-&-1&-GO:0032801-&&-receptor catabolic process-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0035493-&&-SNARE complex assembly-%%-GO:0051684-&&-maintenance of Golgi location-%%-GO:0051297-&&-centrosome organization-%%-GO:0046718-&&-viral entry into host cell-%%-GO:1901098-&&-positive regulation of autophagosome maturation-%%-GO:0071985-&&-multivesicular body sorting pathway-%%-GO:0006281-&&-DNA repair-%%-GO:0006914-&&-autophagy-%%-GO:0071900-&&-regulation of protein serine/threonine kinase activity-%%-GO:0007051-&&-spindle organization-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0007059-&&-chromosome segregation-%%-GO:0097680-&&-double-strand break repair via classical nonhomologous end joining-%%-GO:0060627-&&-regulation of vesicle-mediated transport|cellular_component-&-1&-GO:0030496-&&-midbody-%%-GO:0030897-&&-HOPS complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0000775-&&-chromosome, centromeric region-%%-GO:0005770-&&-late endosome-%%-GO:0070418-&&-DNA-dependent protein kinase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005813-&&-centrosome-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0000149-&&-SNARE binding	G:9606:UVRAG			KEGG-&-1&-hsa04140-&&-Autophagy - animal	UVRAG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UVRAG	0.35539504	0.0952381	15	4	FALSE	UVRAG	UVRAG	109.0666667	0	15	0	0.69770495	FALSE	0	UVRAG	17788	0.07983358
788977	taxon:9606	2.75106349	3.94E-05	176482	1902	zinc finger and SCAN domain containing 21	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZSCAN21				ZSCAN21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZSCAN21	0.36349579	0.13333333	15	4	FALSE	ZSCAN21	ZSCAN21	143.9333333	0	15	0	0.70815608	FALSE	0	ZSCAN21	44642	0.08437133
789045	taxon:9606	2.81314007	5.37E-06	159913	1902	NHL repeat containing E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:NHLRC1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	NHLRC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NHLRC1	0.35547466	0.08974359	15	4	FALSE	NHLRC1	NHLRC1	162.5384615	0	14	0	0.69780999	FALSE	1	NHLRC1	12188	0.12122433
789056	taxon:9606	2.69182291	8.05E-06	176275	1902	dual specificity tyrosine phosphorylation regulated kinase 4	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:DYRK4				DYRK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYRK4	0.37149546	0.0952381	15	4	FALSE	DYRK4	DYRK4	191.2	0	15	0	0.71802952	FALSE	0	DYRK4	14214	0.09304065
789087	taxon:9606	2.66960769	2.79E-05	176212	1902	immediate early response 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010941-&&-regulation of cell death-%%-GO:2001020-&&-regulation of response to DNA damage stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:IER3				IER3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IER3	0.37458687	0.23809524	15	4	FALSE	IER3	IER3	210.1333333	0	15	0	0.72173205	FALSE	0	IER3	26366	0.09726725
789110	taxon:9606	2.68993225	3.20E-05	176182	1902	adaptor related protein complex 1 gamma 2 subunit	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport-%%-GO:0016032-&&-viral process-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0030121-&&-AP-1 adaptor complex-%%-GO:0010008-&&-endosome membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0005798-&&-Golgi-associated vesicle|molecular_function-&-1&-GO:0008565-&&-protein transporter activity-%%-GO:0005515-&&-protein binding	G:9606:AP1G2			KEGG-&-1&-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04142-&&-Lysosome	AP1G2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AP1G2	0.37175657	0.15238095	15	4	FALSE	AP1G2	AP1G2	175.8	0	15	0	0.71834462	FALSE	0	AP1G2	30898	0.0853528
789309	taxon:9606	2.63967229	1.42E-05	175773	1902	SH3 domain binding protein 5	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0061099-&&-negative regulation of protein tyrosine kinase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0017124-&&-SH3 domain binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:SH3BP5				SH3BP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3BP5	0.37883491	0.13333333	15	4	FALSE	SH3BP5	SH3BP5	218.4666667	0	15	0	0.72672129	FALSE	0	SH3BP5	21694	0.09278935
789325	taxon:9606	2.86970222	1.11E-05	175734	1902	myosin heavy chain 13	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction-%%-GO:0009267-&&-cellular response to starvation|cellular_component-&-1&-GO:0005859-&&-muscle myosin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030016-&&-myofibril-%%-GO:0032982-&&-myosin filament|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005516-&&-calmodulin binding	G:9606:MYH13			KEGG-&-1&-hsa04530-&&-Tight junction	MYH13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH13	0.34846821	0.01904762	15	4	FALSE	MYH13	MYH13	82.26666667	0	15	0	0.68838296	FALSE	0	MYH13	13790	0.080487
789368	taxon:9606	2.76303766	8.87E-06	175648	1902	RALBP1 associated Eps domain containing 2	gene	biological_process-&-1&-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:REPS2				REPS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REPS2	0.36192051	0.15238095	15	4	FALSE	REPS2	REPS2	150.6	0	15	0	0.70616039	FALSE	0	REPS2	16150	0.09563189
789411	taxon:9606	2.78525288	8.31E-06	175543	1902	zinc finger HIT-type containing 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0046966-&&-thyroid hormone receptor binding	G:9606:ZNHIT3				ZNHIT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNHIT3	0.35903383	0.06666667	15	4	FALSE	ZNHIT3	ZNHIT3	135.7333333	0	15	0	0.70245785	FALSE	0	ZNHIT3	14520	0.0898185
789527	taxon:9606	2.69922798	3.17E-05	175259	1902	RWD domain containing 2B	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:RWDD2B				RWDD2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RWDD2B	0.3704763	0.07619048	15	5	FALSE	RWDD2B	RWDD2B	164.3333333	0	15	0	0.71679534	FALSE	0	RWDD2B	29370	0.08262769
789566	taxon:9606	2.65763353	1.43E-05	175164	1902	RUN and SH3 domain containing 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding	G:9606:RUSC2				RUSC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUSC2	0.3762746	0.0952381	15	4	FALSE	RUSC2	RUSC2	204.4	0	15	0	0.72372775	FALSE	0	RUSC2	21338	0.09041501
789653	taxon:9606	2.65243422	1.68E-05	174968	1902	myosin light chain 9	gene	biological_process-&-1&-GO:0006937-&&-regulation of muscle contraction-%%-GO:0006936-&&-muscle contraction-%%-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005859-&&-muscle myosin complex-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0001725-&&-stress fiber|molecular_function-&-1&-GO:0032036-&&-myosin heavy chain binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:MYL9			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04530-&&-Tight junction-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MYL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL9	0.37701218	0.16190476	15	4	FALSE	MYL9	MYL9	234	0	15	0	0.7245943	FALSE	0	MYL9	27842	0.10191805
789663	taxon:9606	2.69844021	1.73E-05	174945	1902	progesterone receptor membrane component 2	gene	biological_process-&-1&-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0020037-&&-heme binding-%%-GO:0005496-&&-steroid binding-%%-GO:0005515-&&-protein binding	G:9606:PGRMC2				PGRMC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGRMC2	0.37058446	0.05714286	15	4	FALSE	PGRMC2	PGRMC2	219.7333333	0	15	0	0.71692663	FALSE	0	PGRMC2	35826	0.10642083
789681	taxon:9606	2.62076572	1.57E-05	174910	1902	component of oligomeric golgi complex 5	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000139-&&-Golgi membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:COG5				COG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG5	0.38156787	0.28571429	15	4	FALSE	COG5	COG5	246.6666667	0	15	0	0.72987238	FALSE	0	COG5	24602	0.1001219
789715	taxon:9606	2.66929258	2.12E-05	174839	1902	anterior gradient 2, protein disulphide isomerase family member	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1903896-&&-positive regulation of IRE1-mediated unfolded protein response-%%-GO:0070254-&&-mucus secretion-%%-GO:1903899-&&-positive regulation of PERK-mediated unfolded protein response-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0060480-&&-lung goblet cell differentiation-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0002162-&&-dystroglycan binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding	G:9606:AGR2				AGR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGR2	0.37463109	0.05714286	15	4	FALSE	AGR2	AGR2	194.3333333	0	15	0	0.72178457	FALSE	0	AGR2	36922	0.0898161
789802	taxon:9606	2.9004254	1.22E-05	174628	1902	connector enhancer of kinase suppressor of Ras 1	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0007266-&&-Rho protein signal transduction|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:CNKSR1				CNKSR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNKSR1	0.34477701	0.0952381	15	4	FALSE	CNKSR1	CNKSR1	73.6	0	15	0	0.68326243	FALSE	0	CNKSR1	12274	0.08701504
789855	taxon:9606	2.62517725	6.17E-06	174507	1902	endoplasmic reticulum protein 29	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0043335-&&-protein unfolding-%%-GO:1902235-&&-regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0009306-&&-protein secretion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0006457-&&-protein folding-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050709-&&-negative regulation of protein secretion-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0016020-&&-membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0003756-&&-protein disulfide isomerase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0051087-&&-chaperone binding	G:9606:ERP29			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	ERP29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERP29	0.38092666	0.14102564	15	4	FALSE	ERP29	ERP29	314.8461539	0	14	0	0.72913713	FALSE	1	ERP29	20512	0.12827833
789906	taxon:9606	2.84969277	7.23E-06	174388	1902	growth arrest specific 2 like 1	gene	biological_process-&-1&-GO:0009267-&&-cellular response to starvation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0046966-&&-thyroid hormone receptor binding-%%-GO:0008093-&&-cytoskeletal adaptor activity	G:9606:GAS2L1				GAS2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAS2L1	0.35091502	0.08571429	15	4	FALSE	GAS2L1	GAS2L1	110.0666667	0	15	0	0.69171787	FALSE	0	GAS2L1	10264	0.09486736
789949	taxon:9606	2.78225934	6.43E-06	174272	1902	IQ motif containing GTPase activating protein 2	gene	biological_process-&-1&-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation-%%-GO:0007165-&&-signal transduction-%%-GO:0070493-&&-thrombin-activated receptor signaling pathway-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005902-&&-microvillus-%%-GO:0005886-&&-plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0031941-&&-filamentous actin|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0071933-&&-Arp2/3 complex binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding	G:9606:IQGAP2			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	IQGAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQGAP2	0.35942013	0.06410256	15	4	FALSE	IQGAP2	IQGAP2	149.5384615	0	14	0	0.70295678	FALSE	1	IQGAP2	12186	0.10175899
789998	taxon:9606	2.86308492	1.89E-05	174148	1902	connector enhancer of kinase suppressor of Ras 2	gene	biological_process-&-1&-GO:0009966-&&-regulation of signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0042802-&&-identical protein binding	G:9606:CNKSR2				CNKSR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNKSR2	0.34927361	0.03809524	15	5	FALSE	CNKSR2	CNKSR2	92.13333333	0	15	0	0.68948585	FALSE	0	CNKSR2	20154	0.08377635
790026	taxon:9606	2.74192532	1.39E-05	174065	1902	Pim-2 proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0006915-&&-apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0008283-&&-cell proliferation-%%-GO:0050821-&&-protein stabilization-%%-GO:0009615-&&-response to virus-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007140-&&-male meiosis|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PIM2			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05200-&&-Pathways in cancer	PIM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIM2	0.36470723	0.06666667	15	4	FALSE	PIM2	PIM2	157.6	0	15	0	0.70967911	FALSE	0	PIM2	19826	0.09030651
790107	taxon:9606	2.70710572	9.58E-06	173867	1902	Rho related BTB domain containing 2	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:RHOBTB2			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	RHOBTB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOBTB2	0.36939821	0.17948718	15	4	FALSE	RHOBTB2	RHOBTB2	218.1538462	0	14	0	0.71548238	FALSE	1	RHOBTB2	15338	0.11122024
790120	taxon:9606	2.74334331	1.42E-05	157453	1902	mitochondrial inner membrane organizing system 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:MINOS1				MINOS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MINOS1	0.36451872	0.19047619	15	4	FALSE	MINOS1	MINOS1	151.2	0	15	0	0.70944278	FALSE	0	MINOS1	13676	0.08866706
790254	taxon:9606	2.6932409	8.60E-06	173504	1902	ubiquitin specific peptidase 24	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP24				USP24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP24	0.37129987	0.1047619	15	4	FALSE	USP24	USP24	214.0666667	0	15	0	0.71779318	FALSE	0	USP24	18460	0.10410781
790278	taxon:9606	2.81692138	4.57E-06	173458	1902	zinc finger protein, FOG family member 2	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0003221-&&-right ventricular cardiac muscle tissue morphogenesis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000195-&&-negative regulation of female gonad development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048568-&&-embryonic organ development-%%-GO:0007596-&&-blood coagulation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0003148-&&-outflow tract septum morphogenesis-%%-GO:0007506-&&-gonadal mesoderm development-%%-GO:2000020-&&-positive regulation of male gonad development-%%-GO:0060045-&&-positive regulation of cardiac muscle cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030324-&&-lung development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008134-&&-transcription factor binding	G:9606:ZFPM2			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	ZFPM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFPM2	0.35499748	0.36190476	15	5	FALSE	ZFPM2	ZFPM2	159	0	15	0	0.69717977	FALSE	0	ZFPM2	8274	0.12291828
790370	taxon:9606	2.87143532	1.39E-05	173202	1902	ATPase H+ transporting V0 subunit a2	gene	biological_process-&-1&-GO:0015991-&&-ATP hydrolysis coupled proton transport-%%-GO:0015986-&&-ATP synthesis coupled proton transport-%%-GO:0007035-&&-vacuolar acidification-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0033572-&&-transferrin transport-%%-GO:0016241-&&-regulation of macroautophagy-%%-GO:0006955-&&-immune response-%%-GO:0070072-&&-vacuolar proton-transporting V-type ATPase complex assembly-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0090383-&&-phagosome acidification|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0000220-&&-vacuolar proton-transporting V-type ATPase, V0 domain-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0010008-&&-endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016471-&&-vacuolar proton-transporting V-type ATPase complex-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0046961-&&-proton-transporting ATPase activity, rotational mechanism	G:9606:ATP6V0A2			KEGG-&-1&-hsa00190-&&-Oxidative phosphorylation-%%-hsa04966-&&-Collecting duct acid secretion-%%-hsa04145-&&-Phagosome-%%-hsa01100-&&-Metabolic pathways-%%-hsa05152-&&-Tuberculosis-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa04142-&&-Lysosome-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05323-&&-Rheumatoid arthritis	ATP6V0A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP6V0A2	0.34825789	0.06666667	15	5	FALSE	ATP6V0A2	ATP6V0A2	89.46666667	0	15	0	0.68809411	FALSE	0	ATP6V0A2	16754	0.08908909
790371	taxon:9606	2.82464156	6.40E-06	173196	1902	RASD family member 2	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:0001963-&&-synaptic transmission, dopaminergic-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043949-&&-regulation of cAMP-mediated signaling-%%-GO:0031397-&&-negative regulation of protein ubiquitination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0005525-&&-GTP binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:RASD2				RASD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASD2	0.35402722	0.26666667	15	4	FALSE	RASD2	RASD2	135.9333333	0	15	0	0.69589307	FALSE	0	RASD2	10178	0.11011905
790420	taxon:9606	2.80163857	1.86E-05	173044	1902	apolipoprotein L2	gene	biological_process-&-1&-GO:0006629-&&-lipid metabolic process-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0006869-&&-lipid transport-%%-GO:0007275-&&-multicellular organism development-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0006953-&&-acute-phase response|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008289-&&-lipid binding-%%-GO:0005102-&&-receptor binding-%%-GO:0008035-&&-high-density lipoprotein particle binding	G:9606:APOL2				APOL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOL2	0.35693398	0.01904762	15	4	FALSE	APOL2	APOL2	114.1333333	0	15	0	0.69972691	FALSE	0	APOL2	20420	0.08376447
790440	taxon:9606	2.71419568	1.63E-05	156588	1902	dihydrofolate reductase pseudogene 1	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0031103-&&-axon regeneration-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006545-&&-glycine biosynthetic process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0046654-&&-tetrahydrofolate biosynthetic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0031427-&&-response to methotrexate-%%-GO:0046452-&&-dihydrofolate metabolic process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0033560-&&-folate reductase activity-%%-GO:0004146-&&-dihydrofolate reductase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0070402-&&-NADPH binding-%%-GO:0005542-&&-folic acid binding-%%-GO:0051870-&&-methotrexate binding	G:9606:DHFRP1				DHFRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHFRP1	0.36843327	0.24358974	15	4	FALSE	DHFRP1	DHFRP1	207.6923077	0	14	0	0.71430072	FALSE	1	DHFRP1	23096	0.109832
790446	taxon:9606	2.66172995	1.43E-05	172837	1902	zinc finger protein 318	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding	G:9606:ZNF318				ZNF318	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF318	0.37569551	0.08571429	15	4	FALSE	ZNF318	ZNF318	248.3333333	0	15	0	0.72304501	FALSE	0	ZNF318	23814	0.11083296
790468	taxon:9606	2.56499133	3.87E-06	172773	1902	LSM14A, mRNA processing body assembly factor	gene	biological_process-&-1&-GO:0033962-&&-cytoplasmic mRNA processing body assembly-%%-GO:0006417-&&-regulation of translation-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0039529-&&-RIG-I signaling pathway-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003727-&&-single-stranded RNA binding	G:9606:LSM14A				LSM14A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM14A	0.38986486	0.3047619	15	4	FALSE	LSM14A	LSM14A	328.6	0	15	0	0.73916811	FALSE	0	LSM14A	12958	0.1154603
790507	taxon:9606	3.06002836	1.21E-05	172659	1902	tetraspanin 17	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0072594-&&-establishment of protein localization to organelle|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019899-&&-enzyme binding	G:9606:TSPAN17				TSPAN17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPAN17	0.32679436	0	15	5	FALSE	TSPAN17	TSPAN17	24.13333333	0	15	0	0.65666194	FALSE	0	TSPAN17	9032	0.08261905
790518	taxon:9606	2.64077517	3.28E-05	172640	1902	ADP ribosylation factor GTPase activating protein 3	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0009306-&&-protein secretion-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:ARFGAP3			KEGG-&-1&-hsa04144-&&-Endocytosis	ARFGAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGAP3	0.37867669	0.1047619	15	4	FALSE	ARFGAP3	ARFGAP3	211.7333333	0	15	0	0.72653747	FALSE	0	ARFGAP3	38190	0.08978495
790733	taxon:9606	2.82637467	1.97E-05	154974	1902	forkhead box D4-like 6	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXD4L6				FOXD4L6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXD4L6	0.35381013	0.08571429	15	4	FALSE	FOXD4L6	FOXD4L6	114.2666667	0	15	0	0.69560422	FALSE	0	FOXD4L6	18812	0.09018987
790805	taxon:9606	2.90767292	3.96E-05	171153	1902	SRY-box 8	gene	biological_process-&-1&-GO:0048484-&&-enteric nervous system development-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0090184-&&-positive regulation of kidney development-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0072034-&&-renal vesicle induction-%%-GO:0045165-&&-cell fate commitment-%%-GO:0060018-&&-astrocyte fate commitment-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0014015-&&-positive regulation of gliogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0060612-&&-adipose tissue development-%%-GO:0072289-&&-metanephric nephron tubule formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008584-&&-male gonad development-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0048469-&&-cell maturation-%%-GO:0046533-&&-negative regulation of photoreceptor cell differentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0061138-&&-morphogenesis of a branching epithelium-%%-GO:0072197-&&-ureter morphogenesis-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0010817-&&-regulation of hormone levels-%%-GO:0060221-&&-retinal rod cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0044798-&&-nuclear transcription factor complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:SOX8				SOX8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX8	0.34391764	0.13333333	15	5	FALSE	SOX8	SOX8	107.5333333	0	15	0	0.68205451	FALSE	0	SOX8	38336	0.11787546
790877	taxon:9606	2.87348354	8.50E-06	170792	1902	zinc finger protein 593	gene	biological_process-&-1&-GO:0009245-&&-lipid A biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000055-&&-ribosomal large subunit export from nucleus-%%-GO:1903026-&&-negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030687-&&-preribosome, large subunit precursor-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000035-&&-acyl binding-%%-GO:0031177-&&-phosphopantetheine binding-%%-GO:0000036-&&-ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0043023-&&-ribosomal large subunit binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF593				ZNF593	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF593	0.34800965	0.04761905	15	5	FALSE	ZNF593	ZNF593	77.53333333	0	15	0	0.68775274	FALSE	0	ZNF593	10116	0.07962771
790961	taxon:9606	2.77170317	1.31E-05	170587	1902	BTB domain containing 1	gene	biological_process-&-1&-GO:0030162-&&-regulation of proteolysis-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0022008-&&-neurogenesis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000932-&&-P-body-%%-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:BTBD1				BTBD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTBD1	0.36078899	0.40952381	15	4	FALSE	BTBD1	BTBD1	189.4	0	15	0	0.70471614	FALSE	0	BTBD1	15036	0.11833333
790992	taxon:9606	2.72475185	2.37E-05	170469	1902	aspartyl-tRNA synthetase 2, mitochondrial	gene	biological_process-&-1&-GO:0070145-&&-mitochondrial asparaginyl-tRNA aminoacylation-%%-GO:0006418-&&-tRNA aminoacylation for protein translation-%%-GO:0043039-&&-tRNA aminoacylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004815-&&-aspartate-tRNA ligase activity-%%-GO:0050560-&&-aspartate-tRNA(Asn) ligase activity-%%-GO:0000049-&&-tRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:DARS2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	DARS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DARS2	0.3670059	0.06666667	15	4	FALSE	DARS2	DARS2	173.2666667	0	15	0	0.71254136	FALSE	0	DARS2	30834	0.09167109
791028	taxon:9606	2.98534741	9.95E-05	170315	1902	dipeptidyl peptidase 8	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008239-&&-dipeptidyl-peptidase activity	G:9606:DPP8				DPP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPP8	0.33496939	0.0952381	15	4	FALSE	DPP8	DPP8	46.66666667	0	15	0	0.66910877	FALSE	0	DPP8	126160	0.09081365
791031	taxon:9606	2.57003309	1.42E-05	170302	1902	non-SMC condensin II complex subunit G2	gene	biological_process-&-1&-GO:0001833-&&-inner cell mass cell proliferation-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0030261-&&-chromosome condensation|cellular_component-&-1&-GO:0000796-&&-condensin complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035064-&&-methylated histone binding	G:9606:NCAPG2				NCAPG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCAPG2	0.38910005	0.25714286	15	4	FALSE	NCAPG2	NCAPG2	305.2	0	15	0	0.73832782	FALSE	0	NCAPG2	30390	0.10926457
791081	taxon:9606	2.76035922	2.15E-05	170122	1902	chromosome 11 open reading frame 57	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C11orf57				C11orf57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C11orf57	0.36227169	0.08571429	15	4	FALSE	C11orf57	C11orf57	149.6666667	0	15	0	0.7066068	FALSE	0	C11orf57	26752	0.09125382
791113	taxon:9606	2.89601386	6.63E-06	170000	1902	TBC1 domain family member 2	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0012505-&&-endomembrane system-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0045296-&&-cadherin binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D2				TBC1D2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D2	0.34530221	0.05714286	15	5	FALSE	TBC1D2	TBC1D2	82.46666667	0	15	0	0.68399769	FALSE	0	TBC1D2	9028	0.09315172
791155	taxon:9606	2.71876477	1.26E-05	169868	1902	NLR family pyrin domain containing 2	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032090-&&-Pyrin domain binding-%%-GO:0005515-&&-protein binding	G:9606:NLRP2				NLRP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP2	0.36781409	0.0952381	15	4	FALSE	NLRP2	NLRP2	171.4666667	0	15	0	0.7135392	FALSE	0	NLRP2	17620	0.09284165
791194	taxon:9606	2.59098787	1.98E-05	169772	1902	N-glycanase 1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006516-&&-glycoprotein catabolic process-%%-GO:0006515-&&-misfolded or incompletely synthesized protein catabolic process-%%-GO:0006517-&&-protein deglycosylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000224-&&-peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:NGLY1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	NGLY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NGLY1	0.38595318	0.2	15	4	FALSE	NGLY1	NGLY1	258.2	0	15	0	0.73483536	FALSE	0	NGLY1	26666	0.09770376
791206	taxon:9606	2.82448401	2.39E-05	169731	1902	docking protein 5	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0051386-&&-regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK5				DOK5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK5	0.35404697	0.04761905	15	5	FALSE	DOK5	DOK5	104.3333333	0	15	0	0.69591933	FALSE	0	DOK5	24464	0.08325308
791216	taxon:9606	2.53158973	8.42E-06	169714	1902	p21 (RAC1) activated kinase 6	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0000278-&&-mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:PAK6			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa04660-&&-T cell receptor signaling pathway	PAK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAK6	0.39500871	0.2	15	4	FALSE	PAK6	PAK6	322.6666667	0	15	0	0.74473505	FALSE	0	PAK6	28424	0.10714048
791259	taxon:9606	2.869072	1.04E-05	169475	1902	MIF4G domain containing	gene	biological_process-&-1&-GO:0006417-&&-regulation of translation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:MIF4GD				MIF4GD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MIF4GD	0.34854476	0.02857143	15	5	FALSE	MIF4GD	MIF4GD	85.8	0	15	0	0.688488	FALSE	0	MIF4GD	11472	0.08599327
791355	taxon:9606	2.6051678	1.29E-05	169036	1902	THADA, armadillo repeat containing	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:THADA	THADA	TRUE		THADA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THADA	0.38385243	0.24761905	15	4	FALSE	THADA	THADA	274.8666667	0	15	0	0.73247203	FALSE	0	THADA	30146	0.10622342
791363	taxon:9606	2.70773594	1.64E-05	168965	1902	S100 calcium binding protein A14	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0071624-&&-positive regulation of granulocyte chemotaxis-%%-GO:0006915-&&-apoptotic process-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway-%%-GO:0055074-&&-calcium ion homeostasis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0042379-&&-chemokine receptor binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:S100A14				S100A14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A14	0.36931223	0.02857143	15	4	FALSE	S100A14	S100A14	177	0	15	0	0.71537734	FALSE	0	S100A14	24574	0.0918534
791382	taxon:9606	2.94910982	1.85E-05	168857	1902	NLR family CARD domain containing 4	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0045087-&&-innate immune response-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0016045-&&-detection of bacterium-%%-GO:0050702-&&-interleukin-1 beta secretion-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0002218-&&-activation of innate immune response-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006954-&&-inflammatory response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0070269-&&-pyroptosis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0072557-&&-IPAF inflammasome complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process	G:9606:NLRC4	NLRC4	TRUE	KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05134-&&-Legionellosis	NLRC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRC4	0.33908537	0.15384615	15	4	FALSE	NLRC4	NLRC4	60.15384615	0	14	0	0.67514836	FALSE	1	NLRC4	14082	0.09412477
791408	taxon:9606	2.7594139	2.33E-05	168758	1902	required for meiotic nuclear division 5 homolog A	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0034657-&&-GID complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RMND5A				RMND5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RMND5A	0.3623958	0.2	15	4	FALSE	RMND5A	RMND5A	129.1333333	0	15	0	0.70676435	FALSE	0	RMND5A	27154	0.07831715
791429	taxon:9606	2.68567827	8.68E-06	168682	1902	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	gene	biological_process-&-1&-GO:0048675-&&-axon extension-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030175-&&-filopodium-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RAPH1				RAPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAPH1	0.37234542	0.21904762	15	4	FALSE	RAPH1	RAPH1	183.9333333	0	15	0	0.71905362	FALSE	0	RAPH1	17888	0.0887494
791484	taxon:9606	2.75232393	8.98E-06	168450	1902	TSPY like 2	gene	biological_process-&-1&-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0009966-&&-regulation of signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0007049-&&-cell cycle-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0008156-&&-negative regulation of DNA replication-%%-GO:0045786-&&-negative regulation of cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000182-&&-rDNA binding-%%-GO:0005515-&&-protein binding	G:9606:TSPYL2				TSPYL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPYL2	0.36332933	0.11428571	15	4	FALSE	TSPYL2	TSPYL2	165.2	0	15	0	0.70794601	FALSE	0	TSPYL2	14144	0.09860447
791509	taxon:9606	2.86749646	3.76E-06	168346	1902	IKAROS family zinc finger 4	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043425-&&-bHLH transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:IKZF4				IKZF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IKZF4	0.34873626	0.38461538	15	5	FALSE	IKZF4	IKZF4	127.4615385	0	14	0	0.68875059	FALSE	1	IKZF4	4920	0.12147681
791561	taxon:9606	2.89711675	2.73E-05	168038	1902	cyclin J like	gene	cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:CCNJL				CCNJL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNJL	0.34517076	0.04761905	15	5	FALSE	CCNJL	CCNJL	77.2	0	15	0	0.68381388	FALSE	0	CCNJL	26608	0.08987886
791591	taxon:9606	2.8374035	1.46E-05	167910	1902	elongation factor for RNA polymerase II 3	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0032786-&&-positive regulation of DNA-templated transcription, elongation-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006354-&&-DNA-templated transcription, elongation-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator|cellular_component-&-1&-GO:0008023-&&-transcription elongation factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0035326-&&-enhancer binding	G:9606:ELL3				ELL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELL3	0.35243489	0.28571429	15	4	FALSE	ELL3	ELL3	104.4666667	0	15	0	0.69376608	FALSE	0	ELL3	17532	0.08300186
791598	taxon:9606	2.52465732	1.09E-04	167879	1902	HECT domain E3 ubiquitin protein ligase 3	gene	biological_process-&-1&-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0019905-&&-syntaxin binding-%%-GO:0005515-&&-protein binding	G:9606:HECTD3				HECTD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HECTD3	0.39609336	0.16190476	15	4	FALSE	HECTD3	HECTD3	305.8666667	0	15	0	0.74589045	FALSE	0	HECTD3	104364	0.09980418
791622	taxon:9606	2.81046164	9.29E-06	167775	1902	zinc finger and BTB domain containing 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZBTB3				ZBTB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB3	0.35581343	0.1047619	15	4	FALSE	ZBTB3	ZBTB3	118.0666667	0	15	0	0.69825639	FALSE	0	ZBTB3	11888	0.08890566
791688	taxon:9606	2.7479124	2.34E-05	167425	1902	Nedd4 family interacting protein 1	gene	biological_process-&-1&-GO:0002829-&&-negative regulation of type 2 immune response-%%-GO:0048294-&&-negative regulation of isotype switching to IgE isotypes-%%-GO:0002761-&&-regulation of myeloid leukocyte differentiation-%%-GO:0032713-&&-negative regulation of interleukin-4 production-%%-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045619-&&-regulation of lymphocyte differentiation-%%-GO:0030001-&&-metal ion transport-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0051224-&&-negative regulation of protein transport-%%-GO:0007034-&&-vacuolar transport-%%-GO:0048302-&&-regulation of isotype switching to IgG isotypes-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:NDFIP1				NDFIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDFIP1	0.36391262	0.19047619	15	4	FALSE	NDFIP1	NDFIP1	161.4	0	15	0	0.70868127	FALSE	0	NDFIP1	24580	0.09473478
791737	taxon:9606	2.75657791	8.22E-06	167127	1902	zinc finger MIZ-type containing 2	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043596-&&-nuclear replication fork-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZMIZ2				ZMIZ2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMIZ2	0.36276863	0.16190476	15	4	FALSE	ZMIZ2	ZMIZ2	156.3333333	0	15	0	0.70723701	FALSE	0	ZMIZ2	11210	0.09343706
791770	taxon:9606	2.73814401	6.61E-06	166953	1902	family with sequence similarity 175 member A	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0006302-&&-double-strand break repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body-%%-GO:0070531-&&-BRCA1-A complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0031593-&&-polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:FAM175A			KEGG-&-1&-hsa03440-&&-Homologous recombination	FAM175A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM175A	0.36521089	0.43809524	15	4	FALSE	FAM175A	FAM175A	184.8666667	0	15	0	0.71030933	FALSE	0	FAM175A	9970	0.10538125
791787	taxon:9606	2.72947849	9.80E-06	166879	1902	hydroxysteroid dehydrogenase like 2	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005777-&&-peroxisome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0003674-&&-molecular_function	G:9606:HSDL2				HSDL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSDL2	0.36637035	0.04761905	15	4	FALSE	HSDL2	HSDL2	181.1333333	0	15	0	0.71175358	FALSE	0	HSDL2	23158	0.09806475
791796	taxon:9606	2.69875532	1.69E-05	166826	1902	cms1 ribosomal small subunit homolog (yeast)	gene	cellular_component-&-1&-GO:0030686-&&-90S preribosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:CMSS1				CMSS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMSS1	0.37054119	0.05714286	15	5	FALSE	CMSS1	CMSS1	180.7333333	0	15	0	0.71687411	FALSE	0	CMSS1	25876	0.09025692
791833	taxon:9606	2.68867181	4.84E-06	166616	1902	ribosomal oxygenase 2	gene	biological_process-&-1&-GO:0030961-&&-peptidyl-arginine hydroxylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0070544-&&-histone H3-K36 demethylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034720-&&-histone H3-K4 demethylation-%%-GO:0042254-&&-ribosome biogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0032452-&&-histone demethylase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0032453-&&-histone demethylase activity (H3-K4 specific)	G:9606:RIOX2				RIOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIOX2	0.37193085	0.33333333	15	4	FALSE	RIOX2	RIOX2	259.4615385	0	14	0	0.7185547	FALSE	1	RIOX2	10868	0.12575543
791995	taxon:9606	2.70789349	4.82E-05	182758	1902	apolipoprotein H	gene	biological_process-&-1&-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0051917-&&-regulation of fibrinolysis-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0033033-&&-negative regulation of myeloid cell apoptotic process-%%-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0031639-&&-plasminogen activation-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0034392-&&-negative regulation of smooth muscle cell apoptotic process-%%-GO:0034197-&&-triglyceride transport-%%-GO:0051006-&&-positive regulation of lipoprotein lipase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0042627-&&-chylomicron-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0034364-&&-high-density lipoprotein particle|molecular_function-&-1&-GO:0060230-&&-lipoprotein lipase activator activity-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0008201-&&-heparin binding-%%-GO:0042802-&&-identical protein binding	G:9606:APOH			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism	APOH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOH	0.36929074	0.14102564	15	4	FALSE	APOH	APOH	184	0	14	0	0.71535108	FALSE	1	APOH	42782	0.09613371
792014	taxon:9606	2.80983142	5.60E-05	182728	1902	biglycan	gene	biological_process-&-1&-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0019800-&&-peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan-%%-GO:0030208-&&-dermatan sulfate biosynthetic process-%%-GO:0008150-&&-biological_process-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0030206-&&-chondroitin sulfate biosynthetic process|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005796-&&-Golgi lumen-%%-GO:0042383-&&-sarcolemma-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:BGN				BGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BGN	0.35589324	0.07619048	15	5	FALSE	BGN	BGN	109.0666667	0	15	0	0.69836143	FALSE	0	BGN	47062	0.07625058
792019	taxon:9606	2.72553963	1.67E-05	182727	1902	carcinoembryonic antigen related cell adhesion molecule 1	gene	biological_process-&-1&-GO:0035726-&&-common myeloid progenitor cell proliferation-%%-GO:0001915-&&-negative regulation of T cell mediated cytotoxicity-%%-GO:1903670-&&-regulation of sprouting angiogenesis-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0038016-&&-insulin receptor internalization-%%-GO:1901143-&&-insulin catabolic process-%%-GO:1903385-&&-regulation of homophilic cell adhesion-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0001525-&&-angiogenesis-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0060312-&&-regulation of blood vessel remodeling-%%-GO:0043318-&&-negative regulation of cytotoxic T cell degranulation-%%-GO:0090331-&&-negative regulation of platelet aggregation-%%-GO:0016477-&&-cell migration-%%-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0045601-&&-regulation of endothelial cell differentiation-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0010594-&&-regulation of endothelial cell migration-%%-GO:0001568-&&-blood vessel development-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0002859-&&-negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0045717-&&-negative regulation of fatty acid biosynthetic process-%%-GO:0038158-&&-granulocyte colony-stimulating factor signaling pathway-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0032692-&&-negative regulation of interleukin-1 production-%%-GO:2000346-&&-negative regulation of hepatocyte proliferation-%%-GO:0007155-&&-cell adhesion-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051055-&&-negative regulation of lipid biosynthetic process-%%-GO:0098742-&&-cell-cell adhesion via plasma-membrane adhesion molecules-%%-GO:2001214-&&-positive regulation of vasculogenesis-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0050900-&&-leukocyte migration-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0031528-&&-microvillus membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0015125-&&-bile acid transmembrane transporter activity-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0031005-&&-filamin binding-%%-GO:0019900-&&-kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0003779-&&-actin binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0003674-&&-molecular_function	G:9606:CEACAM1				CEACAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEACAM1	0.36689982	0.30769231	15	4	FALSE	CEACAM1	CEACAM1	214.6153846	0	14	0	0.71241006	FALSE	1	CEACAM1	19756	0.11792333
792027	taxon:9606	2.67638254	1.59E-05	166329	1902	integrator complex subunit 4	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0016180-&&-snRNA processing|cellular_component-&-1&-GO:0032039-&&-integrator complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:INTS4				INTS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INTS4	0.37363866	0.15238095	15	4	FALSE	INTS4	INTS4	200.2	0	15	0	0.72060291	FALSE	0	INTS4	22614	0.0939095
792040	taxon:9606	2.88340948	1.13E-05	182698	1902	BCL2 interacting protein 3	gene	biological_process-&-1&-GO:0045837-&&-negative regulation of membrane potential-%%-GO:0071279-&&-cellular response to cobalt ion-%%-GO:0097345-&&-mitochondrial outer membrane permeabilization-%%-GO:0048102-&&-autophagic cell death-%%-GO:0000422-&&-mitophagy-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0043653-&&-mitochondrial fragmentation involved in apoptotic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0010940-&&-positive regulation of necrotic cell death-%%-GO:0055093-&&-response to hyperoxia-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0043243-&&-positive regulation of protein complex disassembly-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:1903599-&&-positive regulation of mitophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051607-&&-defense response to virus-%%-GO:0001666-&&-response to hypoxia-%%-GO:1902109-&&-negative regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:1903715-&&-regulation of aerobic respiration-%%-GO:0090141-&&-positive regulation of mitochondrial fission-%%-GO:0010659-&&-cardiac muscle cell apoptotic process-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0008219-&&-cell death-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:1990144-&&-intrinsic apoptotic signaling pathway in response to hypoxia-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:1901998-&&-toxin transport-%%-GO:0010637-&&-negative regulation of mitochondrial fusion-%%-GO:0006915-&&-apoptotic process-%%-GO:0035694-&&-mitochondrial protein catabolic process-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0008626-&&-granzyme-mediated apoptotic signaling pathway-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0016239-&&-positive regulation of macroautophagy-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005739-&&-mitochondrion-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:BNIP3			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05134-&&-Legionellosis	BNIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNIP3	0.34681165	0.08974359	15	5	FALSE	BNIP3	BNIP3	90.46153846	0	14	0	0.68609842	FALSE	1	BNIP3	12066	0.0940618
792052	taxon:9606	2.68378762	1.51E-05	182686	1902	ZFP36 ring finger protein like 1	gene	biological_process-&-1&-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0006915-&&-apoptotic process-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0007507-&&-heart development-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:1901991-&&-negative regulation of mitotic cell cycle phase transition-%%-GO:0045577-&&-regulation of B cell differentiation-%%-GO:0051028-&&-mRNA transport-%%-GO:0045661-&&-regulation of myoblast differentiation-%%-GO:0045616-&&-regulation of keratinocyte differentiation-%%-GO:0072091-&&-regulation of stem cell proliferation-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0061158-&&-3'-UTR-mediated mRNA destabilization-%%-GO:0071364-&&-cellular response to epidermal growth factor stimulus-%%-GO:0071375-&&-cellular response to peptide hormone stimulus-%%-GO:0097403-&&-cellular response to raffinose-%%-GO:0048382-&&-mesendoderm development-%%-GO:1904628-&&-cellular response to phorbol 13-acetate 12-myristate-%%-GO:0008283-&&-cell proliferation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0071472-&&-cellular response to salt stress-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0031440-&&-regulation of mRNA 3'-end processing-%%-GO:1904582-&&-positive regulation of intracellular mRNA localization-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0060712-&&-spongiotrophoblast layer development-%%-GO:0038066-&&-p38MAPK cascade-%%-GO:1900153-&&-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0031086-&&-nuclear-transcribed mRNA catabolic process, deadenylation-independent decay-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0010837-&&-regulation of keratinocyte proliferation-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0000165-&&-MAPK cascade-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045657-&&-positive regulation of monocyte differentiation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0003342-&&-proepicardium development-%%-GO:0006397-&&-mRNA processing-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0000288-&&-nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-%%-GO:0021915-&&-neural tube development-%%-GO:0060710-&&-chorio-allantoic fusion-%%-GO:0001570-&&-vasculogenesis-%%-GO:0009611-&&-response to wounding-%%-GO:1902172-&&-regulation of keratinocyte apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0035925-&&-mRNA 3'-UTR AU-rich region binding-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0071889-&&-14-3-3 protein binding	G:9606:ZFP36L1			KEGG-&-1&-hsa04218-&&-Cellular senescence	ZFP36L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFP36L1	0.37260773	0.12380952	15	4	FALSE	ZFP36L1	ZFP36L1	214.5333333	0	15	0	0.71936873	FALSE	0	ZFP36L1	23962	0.10166113
792153	taxon:9606	2.89002678	1.57E-05	182514	1902	activin A receptor like type 1	gene	biological_process-&-1&-GO:0001974-&&-blood vessel remodeling-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060841-&&-venous blood vessel development-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0001936-&&-regulation of endothelial cell proliferation-%%-GO:0002043-&&-blood vessel endothelial cell proliferation involved in sprouting angiogenesis-%%-GO:0006275-&&-regulation of DNA replication-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045602-&&-negative regulation of endothelial cell differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032332-&&-positive regulation of chondrocyte differentiation-%%-GO:0071773-&&-cellular response to BMP stimulus-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0001525-&&-angiogenesis-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0061298-&&-retina vasculature development in camera-type eye-%%-GO:0032924-&&-activin receptor signaling pathway-%%-GO:0043535-&&-regulation of blood vessel endothelial cell migration-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0090500-&&-endocardial cushion to mesenchymal transition-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0007165-&&-signal transduction-%%-GO:0003203-&&-endocardial cushion morphogenesis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0008015-&&-blood circulation-%%-GO:0051895-&&-negative regulation of focal adhesion assembly-%%-GO:0035912-&&-dorsal aorta morphogenesis-%%-GO:0060840-&&-artery development-%%-GO:0045603-&&-positive regulation of endothelial cell differentiation-%%-GO:0060836-&&-lymphatic endothelial cell differentiation-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061154-&&-endothelial tube morphogenesis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0001946-&&-lymphangiogenesis-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0045766-&&-positive regulation of angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004675-&&-transmembrane receptor protein serine/threonine kinase activity-%%-GO:0046332-&&-SMAD binding-%%-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0048185-&&-activin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0016361-&&-activin receptor activity, type I-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005025-&&-transforming growth factor beta receptor activity, type I-%%-GO:0098821-&&-BMP receptor activity-%%-GO:0005024-&&-transforming growth factor beta-activated receptor activity	G:9606:ACVRL1			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	ACVRL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVRL1	0.34601755	0.25714286	15	4	FALSE	ACVRL1	ACVRL1	80.73333333	0	15	0	0.68499554	FALSE	0	ACVRL1	17558	0.08789531
792155	taxon:9606	2.7694974	4.11E-05	182508	1902	ADAM metallopeptidase domain 10	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0051089-&&-constitutive protein ectodomain proteolysis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051088-&&-PMA-inducible membrane protein ectodomain proteolysis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0042117-&&-monocyte activation-%%-GO:0016485-&&-protein processing-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0034612-&&-response to tumor necrosis factor|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005798-&&-Golgi-associated vesicle-%%-GO:0005615-&&-extracellular space-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0097197-&&-tetraspanin-enriched microdomain-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005102-&&-receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0005178-&&-integrin binding	G:9606:ADAM10			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection	ADAM10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAM10	0.36107635	0.1047619	15	4	FALSE	ADAM10	ADAM10	141.6	0	15	0	0.70508377	FALSE	0	ADAM10	36736	0.08970775
792178	taxon:9606	2.78288955	1.02E-05	182474	1902	ADP ribosylation factor 3	gene	biological_process-&-1&-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:ARF3			KEGG-&-1&-hsa04144-&&-Endocytosis	ARF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARF3	0.35933873	0.14285714	15	4	FALSE	ARF3	ARF3	150	0	15	0	0.70285174	FALSE	0	ARF3	20848	0.09579868
792204	taxon:9606	2.74917284	3.62E-05	182426	1902	asialoglycoprotein receptor 1	gene	biological_process-&-1&-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004873-&&-asialoglycoprotein receptor activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:ASGR1			KEGG-&-1&-hsa04918-&&-Thyroid hormone synthesis	ASGR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASGR1	0.36374577	0.0952381	15	4	FALSE	ASGR1	ASGR1	139	0	15	0	0.70847119	FALSE	0	ASGR1	32702	0.08161664
792205	taxon:9606	2.83409485	7.10E-06	182423	1902	argininosuccinate lyase	gene	biological_process-&-1&-GO:0000050-&&-urea cycle-%%-GO:0042450-&&-arginine biosynthetic process via ornithine|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004056-&&-argininosuccinate lyase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ASL			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01100-&&-Metabolic pathways	ASL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASL	0.35284634	0.06410256	15	4	FALSE	ASL	ASL	116.1538462	0	14	0	0.69431753	FALSE	1	ASL	8962	0.09657121
792260	taxon:9606	2.65448243	1.02E-05	182333	1902	CD59 molecule	gene	biological_process-&-1&-GO:0001775-&&-cell activation-%%-GO:0001971-&&-negative regulation of activation of membrane attack complex-%%-GO:0007596-&&-blood coagulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0043218-&&-compact myelin-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031362-&&-anchored component of external side of plasma membrane-%%-GO:0031982-&&-vesicle-%%-GO:0042383-&&-sarcolemma-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001848-&&-complement binding	G:9606:CD59			KEGG-&-1&-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04610-&&-Complement and coagulation cascades	CD59	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD59	0.37672127	0.18095238	15	4	FALSE	CD59	CD59	241.9333333	0	15	0	0.72425293	FALSE	0	CD59	19740	0.1070922
792314	taxon:9606	2.73373247	9.98E-06	165857	1902	protein phosphatase 1 regulatory inhibitor subunit 14A	gene	biological_process-&-1&-GO:0042325-&&-regulation of phosphorylation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004864-&&-protein phosphatase inhibitor activity	G:9606:PPP1R14A			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction	PPP1R14A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R14A	0.36580024	0.23809524	15	4	FALSE	PPP1R14A	PPP1R14A	166.8	0	15	0	0.71104459	FALSE	0	PPP1R14A	14530	0.09391892
792320	taxon:9606	2.84465102	8.34E-06	182237	1902	cathepsin C	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006508-&&-proteolysis-%%-GO:0001913-&&-T cell mediated cytotoxicity-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0007568-&&-aging-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0010033-&&-response to organic substance-%%-GO:1903052-&&-positive regulation of proteolysis involved in cellular protein catabolic process-%%-GO:0006955-&&-immune response-%%-GO:0048208-&&-COPII vesicle coating|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005813-&&-centrosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0031404-&&-chloride ion binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0016505-&&-peptidase activator activity involved in apoptotic process-%%-GO:0019902-&&-phosphatase binding-%%-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:CTSC			KEGG-&-1&-hsa04210-&&-Apoptosis-%%-hsa04142-&&-Lysosome	CTSC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSC	0.35153697	0.07692308	15	4	FALSE	CTSC	CTSC	110.3076923	0	14	0	0.69255816	FALSE	1	CTSC	9376	0.09535256
792431	taxon:9606	2.4892075	5.43E-06	165651	1902	La ribonucleoprotein domain family member 4	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0006412-&&-translation-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0010494-&&-cytoplasmic stress granule-%%-GO:0005844-&&-polysome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008143-&&-poly(A) binding-%%-GO:0005515-&&-protein binding	G:9606:LARP4				LARP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LARP4	0.40173429	0.34285714	15	4	FALSE	LARP4	LARP4	447.6	0	15	0	0.75179875	FALSE	0	LARP4	16424	0.13660969
792457	taxon:9606	2.89049945	2.07E-04	181986	1902	cytochrome b5 type A	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0046686-&&-response to cadmium ion-%%-GO:1902600-&&-hydrogen ion transmembrane transport-%%-GO:0019852-&&-L-ascorbic acid metabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004129-&&-cytochrome-c oxidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding	G:9606:CYB5A	CYB5A	TRUE		CYB5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYB5A	0.34596097	0.0952381	15	5	FALSE	CYB5A	CYB5A	72.73333333	0	15	0	0.68491676	FALSE	0	CYB5A	186306	0.07588133
792483	taxon:9606	2.74885773	6.10E-05	181945	1902	BCL2 related protein A1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007568-&&-aging-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0021987-&&-cerebral cortex development|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051400-&&-BH domain binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:BCL2A1			KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04064-&&-NF-kappa B signaling pathway	BCL2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2A1	0.36378747	0.14285714	15	5	FALSE	BCL2A1	BCL2A1	136.2666667	0	15	0	0.70852371	FALSE	0	BCL2A1	41092	0.08008633
792509	taxon:9606	2.87600441	1.10E-05	181884	1902	discoidin domain receptor tyrosine kinase 1	gene	biological_process-&-1&-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:1990138-&&-neuron projection extension-%%-GO:0014909-&&-smooth muscle cell migration-%%-GO:0061564-&&-axon development-%%-GO:0007595-&&-lactation-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0010715-&&-regulation of extracellular matrix disassembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007566-&&-embryo implantation-%%-GO:0061302-&&-smooth muscle cell-matrix adhesion-%%-GO:0001952-&&-regulation of cell-matrix adhesion-%%-GO:0043583-&&-ear development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0038062-&&-protein tyrosine kinase collagen receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding-%%-GO:0046872-&&-metal ion binding	G:9606:DDR1				DDR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDR1	0.34770461	0.06410256	15	5	FALSE	DDR1	DDR1	103.2307692	0	14	0	0.6873326	FALSE	1	DDR1	11670	0.10396696
792560	taxon:9606	2.89963762	8.38E-06	165428	1902	basic leucine zipper ATF-like transcription factor 2	gene	biological_process-&-1&-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:BATF2				BATF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BATF2	0.34487068	0.26666667	15	4	FALSE	BATF2	BATF2	91.13333333	0	15	0	0.68339373	FALSE	0	BATF2	10104	0.09884058
792590	taxon:9606	2.65590043	1.31E-05	181755	1902	regulator of calcineurin 1	gene	biological_process-&-1&-GO:0070884-&&-regulation of calcineurin-NFAT signaling cascade-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007417-&&-central nervous system development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0033173-&&-calcineurin-NFAT signaling cascade-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008597-&&-calcium-dependent protein serine/threonine phosphatase regulator activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:RCAN1			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway	RCAN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCAN1	0.37652014	0.17142857	15	4	FALSE	RCAN1	RCAN1	209.5333333	0	15	0	0.7240166	FALSE	0	RCAN1	21732	0.09426426
792645	taxon:9606	2.8126674	3.95E-04	181645	1902	CD40 ligand	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0042100-&&-B cell proliferation-%%-GO:0031295-&&-T cell costimulation-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0045190-&&-isotype switching-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0048305-&&-immunoglobulin secretion-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0050776-&&-regulation of immune response-%%-GO:0032753-&&-positive regulation of interleukin-4 production-%%-GO:0051023-&&-regulation of immunoglobulin secretion-%%-GO:0007257-&&-activation of JUN kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0005174-&&-CD40 receptor binding	G:9606:CD40LG	CD40LG	TRUE	KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05144-&&-Malaria-%%-hsa04660-&&-T cell receptor signaling pathway	CD40LG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD40LG	0.35553439	0.19230769	15	4	FALSE	CD40LG	CD40LG	129.0769231	0	14	0	0.69788877	FALSE	1	CD40LG	318460	0.09713855
792713	taxon:9606	2.71419568	1.63E-05	181509	1902	dihydrofolate reductase	gene	biological_process-&-1&-GO:0009165-&&-nucleotide biosynthetic process-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0031103-&&-axon regeneration-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006545-&&-glycine biosynthetic process-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006729-&&-tetrahydrobiopterin biosynthetic process-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0006730-&&-one-carbon metabolic process-%%-GO:0046654-&&-tetrahydrofolate biosynthetic process-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0031427-&&-response to methotrexate-%%-GO:0046452-&&-dihydrofolate metabolic process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0033560-&&-folate reductase activity-%%-GO:0004146-&&-dihydrofolate reductase activity-%%-GO:0003729-&&-mRNA binding-%%-GO:0070402-&&-NADPH binding-%%-GO:0005542-&&-folic acid binding-%%-GO:0051870-&&-methotrexate binding	G:9606:DHFR			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis-%%-hsa01523-&&-Antifolate resistance	DHFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHFR	0.36843327	0.24358974	15	4	FALSE	DHFR	DHFR	207.6923077	0	14	0	0.71430072	FALSE	1	DHFR	23096	0.109832
792829	taxon:9606	2.71876477	1.33E-05	181293	1902	EPH receptor A3	gene	biological_process-&-1&-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0070507-&&-regulation of microtubule cytoskeleton organization-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0097155-&&-fasciculation of sensory neuron axon-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0016477-&&-cell migration-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0097156-&&-fasciculation of motor neuron axon|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0005515-&&-protein binding	G:9606:EPHA3			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA3	0.36781409	0.17948718	15	4	FALSE	EPHA3	EPHA3	214.0769231	0	14	0	0.7135392	FALSE	1	EPHA3	17632	0.11480625
792855	taxon:9606	2.73940444	1.19E-05	181261	1902	ETS2 repressor factor	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0007049-&&-cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:ERF				ERF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERF	0.36504285	0.07619048	15	4	FALSE	ERF	ERF	156.8666667	0	15	0	0.71009926	FALSE	0	ERF	19078	0.09007868
792880	taxon:9606	2.71687411	3.63E-05	181235	1902	ETS variant 5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007274-&&-neuromuscular synaptic transmission-%%-GO:0048133-&&-male germ-line stem cell asymmetric division-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0007626-&&-locomotory behavior-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0050807-&&-regulation of synapse organization-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ETV5			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer	ETV5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETV5	0.36807005	0.0952381	15	5	FALSE	ETV5	ETV5	167.1333333	0	15	0	0.71385431	FALSE	0	ETV5	34514	0.08697618
792890	taxon:9606	2.85709784	4.05E-05	181209	1902	coagulation factor V	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0006508-&&-proteolysis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0007596-&&-blood coagulation-%%-GO:0008015-&&-blood circulation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0032571-&&-response to vitamin K|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0016020-&&-membrane-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0005515-&&-protein binding	G:9606:F5	F5	TRUE	KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F5	0.35000551	0.07692308	15	4	FALSE	F5	F5	105.6153846	0	14	0	0.69048369	FALSE	1	F5	33020	0.09224022
792898	taxon:9606	2.76886718	2.30E-05	181201	1902	coagulation factor XIII A chain	gene	biological_process-&-1&-GO:0072378-&&-blood coagulation, fibrin clot formation-%%-GO:0018149-&&-peptide cross-linking-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0003810-&&-protein-glutamine gamma-glutamyltransferase activity	G:9606:F13A1	F13A1	TRUE	KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F13A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F13A1	0.36115853	0.15384615	15	5	FALSE	F13A1	F13A1	160	0	14	0	0.7051888	FALSE	1	F13A1	22592	0.10301046
792918	taxon:9606	2.90688514	9.57E-06	181158	1902	GA binding protein transcription factor beta subunit 1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000932-&&-P-body-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding	G:9606:GABPB1				GABPB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABPB1	0.34401084	0.03809524	15	5	FALSE	GABPB1	GABPB1	67.4	0	15	0	0.68218581	FALSE	0	GABPB1	9652	0.0838143
793009	taxon:9606	2.79801481	1.63E-05	164542	1902	UBX domain protein 2B	gene	biological_process-&-1&-GO:0061025-&&-membrane fusion-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0007030-&&-Golgi organization-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043130-&&-ubiquitin binding	G:9606:UBXN2B				UBXN2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBXN2B	0.35739625	0.11428571	15	4	FALSE	UBXN2B	UBXN2B	130.5333333	0	15	0	0.70033086	FALSE	0	UBXN2B	17202	0.09324743
793030	taxon:9606	2.88782102	4.79E-06	180870	1902	glutamate ionotropic receptor AMPA type subunit 4	gene	biological_process-&-1&-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0006810-&&-transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway|cellular_component-&-1&-GO:1903561-&&-extracellular vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030666-&&-endocytic vesicle membrane|molecular_function-&-1&-GO:0004970-&&-ionotropic glutamate receptor activity-%%-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0005231-&&-excitatory extracellular ligand-gated ion channel activity-%%-GO:0004971-&&-AMPA glutamate receptor activity	G:9606:GRIA4			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05031-&&-Amphetamine addiction	GRIA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIA4	0.34628185	0.21794872	15	5	FALSE	GRIA4	GRIA4	95.61538462	0	14	0	0.68536316	FALSE	1	GRIA4	8084	0.10647593
793053	taxon:9606	2.81282496	1.33E-04	180821	1902	glutathione S-transferase mu 4	gene	biological_process-&-1&-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043295-&&-glutathione binding	G:9606:GSTM4			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTM4	0.35551448	0.05128205	15	4	FALSE	GSTM4	GSTM4	147.9230769	0	14	0	0.69786251	FALSE	1	GSTM4	158238	0.10355445
793079	taxon:9606	2.60233181	1.48E-05	180798	1902	BRF1, RNA polymerase III transcription initiation factor subunit	gene	biological_process-&-1&-GO:0045945-&&-positive regulation of transcription from RNA polymerase III promoter-%%-GO:0006384-&&-transcription initiation from RNA polymerase III promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009303-&&-rRNA transcription-%%-GO:0009304-&&-tRNA transcription|cellular_component-&-1&-GO:0000126-&&-transcription factor TFIIIB complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:BRF1				BRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRF1	0.38427075	0.13333333	15	4	FALSE	BRF1	BRF1	243.2	0	15	0	0.7329447	FALSE	0	BRF1	27138	0.09481077
793118	taxon:9606	2.73483536	6.44E-06	180698	1902	growth factor independent 1 transcriptional repressor	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0010956-&&-negative regulation of calcidiol 1-monooxygenase activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0010957-&&-negative regulation of vitamin D biosynthetic process-%%-GO:0070105-&&-positive regulation of interleukin-6-mediated signaling pathway-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0034121-&&-regulation of toll-like receptor signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051569-&&-regulation of histone H3-K4 methylation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0030097-&&-hemopoiesis|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:GFI1				GFI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFI1	0.36565272	0.26666667	15	4	FALSE	GFI1	GFI1	206.3333333	0	15	0	0.71086077	FALSE	0	GFI1	12134	0.11237057
793300	taxon:9606	2.71356546	3.80E-05	180355	1902	hemoglobin subunit delta	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005833-&&-hemoglobin complex-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding	G:9606:HBD				HBD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBD	0.36851884	0.17948718	15	4	FALSE	HBD	HBD	191.5384615	0	14	0	0.71440576	FALSE	1	HBD	40644	0.10041166
793346	taxon:9606	2.66425083	1.44E-05	163878	1902	thiosulfate sulfurtransferase like domain containing 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TSTD2				TSTD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSTD2	0.37534004	0.1047619	15	4	FALSE	TSTD2	TSTD2	208	0	15	0	0.72262486	FALSE	0	TSTD2	26018	0.09400936
787045	taxon:9606	2.58610367	1.79E-05	180165	1902	isocitrate dehydrogenase (NADP(+)) 2, mitochondrial	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:1904465-&&-negative regulation of matrix metallopeptidase secretion-%%-GO:1903976-&&-negative regulation of glial cell migration-%%-GO:0006097-&&-glyoxylate cycle-%%-GO:0006102-&&-isocitrate metabolic process-%%-GO:0060253-&&-negative regulation of glial cell proliferation-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0006741-&&-NADP biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004450-&&-isocitrate dehydrogenase (NADP+) activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0051287-&&-NAD binding	G:9606:IDH2			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa00480-&&-Glutathione metabolism-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways	IDH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IDH2	0.3866821	0.1978022	14	4	FALSE	IDH2	IDH2	290	0	14	0	0.73564939	FALSE	0	IDH2	37558	0.10742094
787112	taxon:9606	2.85158343	4.71E-06	180042	1902	interleukin 7 receptor	gene	biological_process-&-1&-GO:0008361-&&-regulation of cell size-%%-GO:0048872-&&-homeostasis of number of cells-%%-GO:0038111-&&-interleukin-7-mediated signaling pathway-%%-GO:0001915-&&-negative regulation of T cell mediated cytotoxicity-%%-GO:0000018-&&-regulation of DNA recombination-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0033089-&&-positive regulation of T cell differentiation in thymus-%%-GO:0042100-&&-B cell proliferation-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0048535-&&-lymph node development-%%-GO:0016049-&&-cell growth-%%-GO:0007165-&&-signal transduction-%%-GO:0006955-&&-immune response-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0030217-&&-T cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003823-&&-antigen binding-%%-GO:0004917-&&-interleukin-7 receptor activity-%%-GO:0005515-&&-protein binding	G:9606:IL7R			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL7R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL7R	0.35068236	0.45054945	14	5	FALSE	IL7R	IL7R	132.1428571	0	14	0	0.69140276	FALSE	0	IL7R	7098	0.11898327
787154	taxon:9606	2.92736726	9.48E-06	163585	1902	family with sequence similarity 84 member B	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM84B				FAM84B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM84B	0.34160388	0.01098901	14	5	FALSE	FAM84B	FAM84B	69.42857143	0	14	0	0.67877212	FALSE	0	FAM84B	9714	0.0931677
787195	taxon:9606	2.70710572	4.46E-05	179899	1902	myelin associated glycoprotein	gene	biological_process-&-1&-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0050900-&&-leukocyte migration-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048711-&&-positive regulation of astrocyte differentiation-%%-GO:0050771-&&-negative regulation of axonogenesis-%%-GO:0022010-&&-central nervous system myelination-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0007155-&&-cell adhesion-%%-GO:0098742-&&-cell-cell adhesion via plasma-membrane adhesion molecules|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0005886-&&-plasma membrane-%%-GO:0043220-&&-Schmidt-Lanterman incisure-%%-GO:0043218-&&-compact myelin-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0097453-&&-mesaxon-%%-GO:0005737-&&-cytoplasm-%%-GO:0033270-&&-paranode region of axon-%%-GO:0035749-&&-myelin sheath adaxonal region|molecular_function-&-1&-GO:0033691-&&-sialic acid binding-%%-GO:0005102-&&-receptor binding-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:1905576-&&-ganglioside GT1b binding	G:9606:MAG			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	MAG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAG	0.36939821	0.08791209	14	5	FALSE	MAG	MAG	172.8571429	0	14	0	0.71548238	FALSE	0	MAG	33570	0.08949863
787238	taxon:9606	2.88262171	5.99E-06	179819	1902	pancreatic and duodenal homeobox 1	gene	biological_process-&-1&-GO:0043388-&&-positive regulation of DNA binding-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0034097-&&-response to cytokine-%%-GO:0035094-&&-response to nicotine-%%-GO:0070542-&&-response to fatty acid-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0048863-&&-stem cell differentiation-%%-GO:0031017-&&-exocrine pancreas development-%%-GO:0003309-&&-type B pancreatic cell differentiation-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0010157-&&-response to chlorate-%%-GO:0010260-&&-animal organ senescence-%%-GO:0010040-&&-response to iron(II) ion-%%-GO:0001889-&&-liver development-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process-%%-GO:0016331-&&-morphogenesis of embryonic epithelium-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0033273-&&-response to vitamin-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051594-&&-detection of glucose-%%-GO:0043201-&&-response to leucine-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0042493-&&-response to drug-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0030073-&&-insulin secretion-%%-GO:0009611-&&-response to wounding-%%-GO:0048565-&&-digestive tract development-%%-GO:0060290-&&-transdifferentiation-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008134-&&-transcription factor binding	G:9606:PDX1			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04911-&&-Insulin secretion-%%-hsa04950-&&-Maturity onset diabetes of the young	PDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDX1	0.34690643	0.12121212	14	5	FALSE	PDX1	PDX1	117.4166667	0	13	0	0.68622971	FALSE	1	PDX1	8428	0.12307423
787247	taxon:9606	2.98944383	5.58E-06	179801	1902	integrin subunit alpha 1	gene	biological_process-&-1&-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0042311-&&-vasodilation-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0006936-&&-muscle contraction-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0045123-&&-cellular extravasation|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0045178-&&-basal part of cell-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0043204-&&-perikaryon-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0034665-&&-integrin alpha1-beta1 complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0098639-&&-collagen binding involved in cell-matrix adhesion-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0046872-&&-metal ion binding	G:9606:ITGA1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA1	0.33451038	0.10606061	14	4	FALSE	ITGA1	ITGA1	52.33333333	0	13	0	0.66842603	FALSE	1	ITGA1	5222	0.10219816
787254	taxon:9606	2.67543721	2.88E-06	179793	1902	inositol-tetrakisphosphate 1-kinase	gene	biological_process-&-1&-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0007596-&&-blood coagulation-%%-GO:0016310-&&-phosphorylation-%%-GO:0016311-&&-dephosphorylation-%%-GO:0021915-&&-neural tube development-%%-GO:0032957-&&-inositol trisphosphate metabolic process|cellular_component-&-1&-GO:0016324-&&-apical plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0052835-&&-inositol-3,4,6-trisphosphate 1-kinase activity-%%-GO:0016853-&&-isomerase activity-%%-GO:0052725-&&-inositol-1,3,4-trisphosphate 6-kinase activity-%%-GO:0047325-&&-inositol tetrakisphosphate 1-kinase activity-%%-GO:0052825-&&-inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity-%%-GO:0052726-&&-inositol-1,3,4-trisphosphate 5-kinase activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0052659-&&-inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity-%%-GO:0052831-&&-inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity-%%-GO:0052830-&&-inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	G:9606:ITPK1			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	ITPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITPK1	0.37377068	0.3030303	14	4	FALSE	ITPK1	ITPK1	275	0	13	0	0.72076046	FALSE	1	ITPK1	7438	0.12751237
787287	taxon:9606	2.88561525	1.74E-05	179732	1902	potassium calcium-activated channel subfamily M alpha 1	gene	biological_process-&-1&-GO:0060083-&&-smooth muscle contraction involved in micturition-%%-GO:0034465-&&-response to carbon monoxide-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0006970-&&-response to osmotic stress-%%-GO:0006813-&&-potassium ion transport-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051592-&&-response to calcium ion-%%-GO:0060073-&&-micturition-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0030007-&&-cellular potassium ion homeostasis-%%-GO:0045794-&&-negative regulation of cell volume-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0060072-&&-large conductance calcium-activated potassium channel activity-%%-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0015269-&&-calcium-activated potassium channel activity	G:9606:KCNMA1	KCNMA1	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04911-&&-Insulin secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	KCNMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNMA1	0.34654655	0.01515152	14	4	FALSE	KCNMA1	KCNMA1	90	0	13	0	0.68573079	FALSE	1	KCNMA1	18556	0.09587814
787324	taxon:9606	2.69292579	3.72E-05	179666	1902	keratin 7	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005882-&&-intermediate filament-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT7				KRT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT7	0.37134332	0.08791209	14	4	FALSE	KRT7	KRT7	189.0714286	0	14	0	0.7178457	FALSE	0	KRT7	39820	0.09338755
787339	taxon:9606	2.75185127	9.27E-06	179625	1902	laminin subunit beta 2	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0072249-&&-metanephric glomerular visceral epithelial cell development-%%-GO:0072274-&&-metanephric glomerular basement membrane development-%%-GO:0007155-&&-cell adhesion-%%-GO:0014044-&&-Schwann cell development-%%-GO:0048677-&&-axon extension involved in regeneration-%%-GO:0007601-&&-visual perception-%%-GO:0007411-&&-axon guidance-%%-GO:0014002-&&-astrocyte development-%%-GO:0060041-&&-retina development in camera-type eye|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005604-&&-basement membrane-%%-GO:0005605-&&-basal lamina-%%-GO:0043083-&&-synaptic cleft-%%-GO:0005608-&&-laminin-3 complex-%%-GO:0043260-&&-laminin-11 complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0005198-&&-structural molecule activity	G:9606:LAMB2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	LAMB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMB2	0.36339173	0.07692308	14	4	FALSE	LAMB2	LAMB2	170.1428571	0	14	0	0.70802479	FALSE	0	LAMB2	16386	0.10179
787353	taxon:9606	2.82889554	1.79E-05	179603	1902	NADH dehydrogenase, subunit 4 (complex I)	gene		G:9606:ND4			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa00190-&&-Oxidative phosphorylation-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa04723-&&-Retrograde endocannabinoid signaling	ND4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ND4	0.35349485	0.17582418	14	4	FALSE	ND4	ND4	113.1428571	0	14	0	0.69518408	FALSE	0	ND4	18648	0.08969704
787374	taxon:9606	2.77138806	3.86E-06	179539	1902	growth arrest and DNA damage inducible beta	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0006950-&&-response to stress-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GADD45B			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05214-&&-Glioma-%%-hsa05213-&&-Endometrial cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05218-&&-Melanoma-%%-hsa04210-&&-Apoptosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05200-&&-Pathways in cancer-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05216-&&-Thyroid cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	GADD45B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GADD45B	0.36083002	0.31868132	14	4	FALSE	GADD45B	GADD45B	163.3571429	0	14	0	0.70476866	FALSE	0	GADD45B	8974	0.1033906
787376	taxon:9606	2.77706003	4.57E-06	179535	1902	myosin heavy chain 2	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006936-&&-muscle contraction-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0001778-&&-plasma membrane repair|cellular_component-&-1&-GO:0030017-&&-sarcomere-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005826-&&-actomyosin contractile ring-%%-GO:0005859-&&-muscle myosin complex-%%-GO:0031672-&&-A band-%%-GO:0043234-&&-protein complex-%%-GO:0030016-&&-myofibril-%%-GO:0032982-&&-myosin filament-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:MYH2			KEGG-&-1&-hsa04530-&&-Tight junction	MYH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH2	0.36009304	0.18681319	14	4	FALSE	MYH2	MYH2	157.2142857	0	14	0	0.70382333	FALSE	0	MYH2	9038	0.10124424
787440	taxon:9606	2.64376871	9.83E-06	179432	1902	DNA ligase 1	gene	biological_process-&-1&-GO:0006266-&&-DNA ligation-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0006284-&&-base-excision repair-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0051301-&&-cell division-%%-GO:0051103-&&-DNA ligation involved in DNA repair-%%-GO:0071897-&&-DNA biosynthetic process-%%-GO:1903461-&&-Okazaki fragment processing involved in mitotic DNA replication-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006297-&&-nucleotide-excision repair, DNA gap filling-%%-GO:0006298-&&-mismatch repair-%%-GO:0033151-&&-V(D)J recombination|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003909-&&-DNA ligase activity-%%-GO:0003910-&&-DNA ligase (ATP) activity-%%-GO:0046872-&&-metal ion binding	G:9606:LIG1			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03410-&&-Base excision repair-%%-hsa03030-&&-DNA replication-%%-hsa03420-&&-Nucleotide excision repair	LIG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIG1	0.37824791	0.16483516	14	4	FALSE	LIG1	LIG1	249.3571429	0	14	0	0.72603855	FALSE	0	LIG1	15554	0.10589772
787459	taxon:9606	2.90467938	1.30E-04	179398	1902	meprin A subunit alpha	gene	biological_process-&-1&-GO:0007586-&&-digestion-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0017090-&&-meprin A complex|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:MEP1A			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	MEP1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEP1A	0.34427208	0.15151515	14	5	FALSE	MEP1A	MEP1A	89.33333333	0	13	0	0.68255344	FALSE	1	MEP1A	155294	0.0981094
787512	taxon:9606	2.77674492	1.33E-05	179308	1902	mannose phosphate isomerase	gene	biological_process-&-1&-GO:0009298-&&-GDP-mannose biosynthetic process-%%-GO:0061611-&&-mannose to fructose-6-phosphate metabolic process-%%-GO:0000032-&&-cell wall mannoprotein biosynthetic process-%%-GO:0006486-&&-protein glycosylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004476-&&-mannose-6-phosphate isomerase activity	G:9606:MPI			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	MPI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPI	0.36013391	0.15384615	14	4	FALSE	MPI	MPI	142.5	0	14	0	0.70387585	FALSE	0	MPI	18038	0.09197525
787517	taxon:9606	2.93776587	1.48E-05	162916	1902	membrane associated guanylate kinase, WW and PDZ domain containing 3	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0046037-&&-GMP metabolic process-%%-GO:0046328-&&-regulation of JNK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0016032-&&-viral process-%%-GO:0046710-&&-GDP metabolic process|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0005515-&&-protein binding-%%-GO:0004385-&&-guanylate kinase activity	G:9606:MAGI3			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway	MAGI3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGI3	0.34039472	0.04395604	14	4	FALSE	MAGI3	MAGI3	58.42857143	0	14	0	0.67703902	FALSE	0	MAGI3	10062	0.08347056
787525	taxon:9606	2.73373247	1.57E-05	162879	1902	centromere protein X	gene	biological_process-&-1&-GO:0031297-&&-replication fork processing-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051382-&&-kinetochore assembly-%%-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071821-&&-FANCM-MHF complex-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:CENPX			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	CENPX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPX	0.36580024	0.30769231	14	4	FALSE	CENPX	CENPX	207.2857143	0	14	0	0.71104459	FALSE	0	CENPX	21880	0.11488789
787599	taxon:9606	2.75232393	3.26E-05	179117	1902	nuclear factor I C	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006260-&&-DNA replication-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:NFIC	NFIC	TRUE		NFIC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFIC	0.36332933	0.0989011	14	4	FALSE	NFIC	NFIC	170.2857143	0	14	0	0.70794601	FALSE	0	NFIC	31074	0.10087273
787643	taxon:9606	2.78777375	1.48E-05	179024	1902	nuclear respiratory factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding	G:9606:NRF1			KEGG-&-1&-hsa04371-&&-Apelin signaling pathway-%%-hsa05016-&&-Huntington disease	NRF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRF1	0.35870917	0.02197802	14	4	FALSE	NRF1	NRF1	141.7857143	0	14	0	0.70203771	FALSE	0	NRF1	17238	0.09350133
787656	taxon:9606	2.6385694	4.41E-05	179006	1902	receptor tyrosine kinase like orphan receptor 2	gene	biological_process-&-1&-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0030539-&&-male genitalia development-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0030282-&&-bone mineralization-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0007254-&&-JNK cascade-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051968-&&-positive regulation of synaptic transmission, glutamatergic-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0014002-&&-astrocyte development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:1900020-&&-positive regulation of protein kinase C activity-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:1905517-&&-macrophage migration-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045165-&&-cell fate commitment-%%-GO:0030538-&&-embryonic genitalia morphogenesis-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0001502-&&-cartilage condensation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0001756-&&-somitogenesis-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005874-&&-microtubule-%%-GO:0009986-&&-cell surface-%%-GO:0030425-&&-dendrite-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:1904929-&&-coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway-%%-GO:0005524-&&-ATP binding	G:9606:ROR2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	ROR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROR2	0.37899325	0.12121212	14	4	FALSE	ROR2	ROR2	260.8333333	0	13	0	0.7269051	FALSE	1	ROR2	38396	0.10953482
787667	taxon:9606	2.81912715	1.06E-05	178991	1902	serpin family A member 4	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031089-&&-platelet dense granule lumen|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINA4	SERPINA4	TRUE		SERPINA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINA4	0.35471972	0.05494505	14	5	FALSE	SERPINA4	SERPINA4	114.1428571	0	14	0	0.69681214	FALSE	0	SERPINA4	14524	0.08922956
787784	taxon:9606	2.88813613	6.67E-06	178795	1902	protein phosphatase 3 regulatory subunit B, beta	gene	molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:PPP3R2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04924-&&-Renin secretion-%%-hsa04720-&&-Long-term potentiation-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04360-&&-Axon guidance-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04022-&&-cGMP-PKG signaling pathway	PPP3R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP3R2	0.34624407	0.02197802	14	5	FALSE	PPP3R2	PPP3R2	99.42857143	0	14	0	0.68531065	FALSE	0	PPP3R2	10828	0.1049036
787791	taxon:9606	2.91334489	5.75E-05	178779	1902	serglycin	gene	biological_process-&-1&-GO:0033373-&&-maintenance of protease location in mast cell secretory granule-%%-GO:0031214-&&-biomineral tissue development-%%-GO:0033382-&&-maintenance of granzyme B location in T cell secretory granule-%%-GO:0033368-&&-protease localization to mast cell secretory granule-%%-GO:0008626-&&-granzyme-mediated apoptotic signaling pathway-%%-GO:0033371-&&-T cell secretory granule organization-%%-GO:0050710-&&-negative regulation of cytokine secretion-%%-GO:0002576-&&-platelet degranulation-%%-GO:0016485-&&-protein processing-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0033364-&&-mast cell secretory granule organization|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0042588-&&-zymogen granule-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0042629-&&-mast cell granule-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding	G:9606:SRGN				SRGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRGN	0.34324807	0.04395604	14	4	FALSE	SRGN	SRGN	73.07142857	0	14	0	0.68110919	FALSE	0	SRGN	66262	0.08972772
787858	taxon:9606	2.7994328	1.23E-05	178700	1902	legumain	gene	biological_process-&-1&-GO:0032801-&&-receptor catabolic process-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0042359-&&-vitamin D metabolic process-%%-GO:0010447-&&-response to acidic pH-%%-GO:0006508-&&-proteolysis-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0003014-&&-renal system process-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006624-&&-vacuolar protein processing-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0040015-&&-negative regulation of multicellular organism growth-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005770-&&-late endosome-%%-GO:0045177-&&-apical part of cell-%%-GO:0005764-&&-lysosome-%%-GO:0036021-&&-endolysosome lumen|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity	G:9606:LGMN			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04142-&&-Lysosome	LGMN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LGMN	0.35721522	0.04545455	14	4	FALSE	LGMN	LGMN	153.3333333	0	13	0	0.70009453	FALSE	1	LGMN	12338	0.10873694
787863	taxon:9606	2.89428076	1.76E-05	178689	1902	HtrA serine peptidase 1	gene	biological_process-&-1&-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0001890-&&-placenta development-%%-GO:0006508-&&-proteolysis-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0060718-&&-chorionic trophoblast cell differentiation-%%-GO:0097187-&&-dentinogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005520-&&-insulin-like growth factor binding-%%-GO:0008236-&&-serine-type peptidase activity	G:9606:HTRA1				HTRA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTRA1	0.34550898	0.04395604	14	4	FALSE	HTRA1	HTRA1	73.71428571	0	14	0	0.68428654	FALSE	0	HTRA1	15454	0.08379751
788438	taxon:9606	2.78225934	2.90E-06	177674	1902	signal-induced proliferation-associated 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0008283-&&-cell proliferation-%%-GO:0042631-&&-cellular response to water deprivation-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045786-&&-negative regulation of cell cycle|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0043234-&&-protein complex-%%-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SIPA1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration	SIPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIPA1	0.35942013	0.34065934	14	5	FALSE	SIPA1	SIPA1	183.0714286	0	14	0	0.70295678	FALSE	0	SIPA1	8366	0.12283986
788646	taxon:9606	2.58846699	7.07E-06	177259	1902	Rho guanine nucleotide exchange factor 5	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0002408-&&-myeloid dendritic cell chemotaxis-%%-GO:1904591-&&-positive regulation of protein import-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0071803-&&-positive regulation of podosome assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0071944-&&-cell periphery-%%-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0002102-&&-podosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005525-&&-GTP binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0008289-&&-lipid binding	G:9606:ARHGEF5				ARHGEF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF5	0.38632905	0.17582418	14	5	FALSE	ARHGEF5	ARHGEF5	282.2857143	0	14	0	0.7352555	FALSE	0	ARHGEF5	19042	0.1061747
788649	taxon:9606	2.80935875	1.47E-04	177254	1902	tissue factor pathway inhibitor	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0032355-&&-response to estradiol-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007598-&&-blood coagulation, extrinsic pathway-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0031090-&&-organelle membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity	G:9606:TFPI			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	TFPI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFPI	0.35595312	0.10989011	14	4	FALSE	TFPI	TFPI	125.9285714	0	14	0	0.69844021	FALSE	0	TFPI	159208	0.09065141
788711	taxon:9606	2.9387112	1.18E-05	160752	1902	C-type lectin domain family 4 member G	gene	biological_process-&-1&-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0002710-&&-negative regulation of T cell mediated immunity-%%-GO:0046718-&&-viral entry into host cell|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030247-&&-polysaccharide binding	G:9606:CLEC4G				CLEC4G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLEC4G	0.34028522	0.03030303	14	4	FALSE	CLEC4G	CLEC4G	68.16666667	0	13	0	0.67688147	FALSE	1	CLEC4G	10134	0.10168426
788732	taxon:9606	2.97951788	8.63E-06	177090	1902	transient receptor potential cation channel subfamily C member 1	gene	biological_process-&-1&-GO:0006828-&&-manganese ion transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0051480-&&-regulation of cytosolic calcium ion concentration-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006816-&&-calcium ion transport-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0042438-&&-melanin biosynthetic process-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0005261-&&-cation channel activity-%%-GO:0070679-&&-inositol 1,4,5 trisphosphate binding-%%-GO:0015279-&&-store-operated calcium channel activity-%%-GO:0005515-&&-protein binding	G:9606:TRPC1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04972-&&-Pancreatic secretion	TRPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPC1	0.33562477	0.1969697	14	5	FALSE	TRPC1	TRPC1	58.58333333	0	13	0	0.67008035	FALSE	1	TRPC1	7286	0.10121107
788742	taxon:9606	2.71955254	1.20E-05	177049	1902	tetratricopeptide repeat domain 3	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:TTC3				TTC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC3	0.36770755	0.10989011	14	4	FALSE	TTC3	TTC3	182.5	0	14	0	0.71340791	FALSE	0	TTC3	16766	0.0984556
788876	taxon:9606	2.91176934	9.44E-06	176714	1902	von Willebrand factor	gene	biological_process-&-1&-GO:0007596-&&-blood coagulation-%%-GO:0009611-&&-response to wounding-%%-GO:0030168-&&-platelet activation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002576-&&-platelet degranulation-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007599-&&-hemostasis-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0033093-&&-Weibel-Palade body-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0002020-&&-protease binding-%%-GO:0005178-&&-integrin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005518-&&-collagen binding-%%-GO:0019865-&&-immunoglobulin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0001948-&&-glycoprotein binding	G:9606:VWF	VWF	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa05165-&&-Human papillomavirus infection	VWF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VWF	0.3434338	0.04545455	14	4	FALSE	VWF	VWF	77.83333333	0	13	0	0.68137178	FALSE	1	VWF	9618	0.10313752
788979	taxon:9606	2.94974003	4.65E-06	176479	1902	zinc finger protein 212	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ZNF212				ZNF212	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF212	0.33901293	0.09090909	14	4	FALSE	ZNF212	ZNF212	58.91666667	0	13	0	0.67504333	FALSE	1	ZNF212	4668	0.10068847
789085	taxon:9606	2.93414211	4.69E-06	176216	1902	period circadian clock 3	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0045187-&&-regulation of circadian sleep/wake cycle, sleep-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:PER3	PER3	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04710-&&-Circadian rhythm-%%-hsa04713-&&-Circadian entrainment	PER3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PER3	0.34081512	0.34065934	14	4	FALSE	PER3	PER3	85.14285714	0	14	0	0.67764298	FALSE	0	PER3	5354	0.11189535
789162	taxon:9606	2.82574445	7.11E-06	176071	1902	protein kinase, membrane associated tyrosine/threonine 1	gene	biological_process-&-1&-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0051726-&&-regulation of cell cycle|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005730-&&-nucleolus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0016301-&&-kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PKMYT1			KEGG-&-1&-hsa04110-&&-Cell cycle-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation	PKMYT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKMYT1	0.35388904	0.16483516	14	4	FALSE	PKMYT1	PKMYT1	127.8571429	0	14	0	0.69570926	FALSE	0	PKMYT1	11880	0.10095012
789217	taxon:9606	2.7646132	5.37E-06	175976	1902	cell division cycle 14B	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0060271-&&-cilium assembly-%%-GO:0051256-&&-mitotic spindle midzone assembly-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006281-&&-DNA repair-%%-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0007096-&&-regulation of exit from mitosis|cellular_component-&-1&-GO:0005813-&&-centrosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005730-&&-nucleolus-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:CDC14B			KEGG-&-1&-hsa04110-&&-Cell cycle	CDC14B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC14B	0.36171425	0.12087912	14	4	FALSE	CDC14B	CDC14B	167.4285714	0	14	0	0.7058978	FALSE	0	CDC14B	11330	0.10185427
789285	taxon:9606	2.8074681	1.51E-05	175824	1902	leupaxin	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007165-&&-signal transduction-%%-GO:0006461-&&-protein complex assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0050859-&&-negative regulation of B cell receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0002102-&&-podosome-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0042995-&&-cell projection|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:LPXN				LPXN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPXN	0.35619283	0.06593407	14	4	FALSE	LPXN	LPXN	129.5	0	14	0	0.69875532	FALSE	0	LPXN	17344	0.09623386
789311	taxon:9606	2.69623444	5.28E-06	175769	1902	A-kinase anchoring protein 6	gene	biological_process-&-1&-GO:0010738-&&-regulation of protein kinase A signaling-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0060316-&&-positive regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:0001508-&&-action potential-%%-GO:1902261-&&-positive regulation of delayed rectifier potassium channel activity-%%-GO:0070886-&&-positive regulation of calcineurin-NFAT signaling cascade-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0061051-&&-positive regulation of cell growth involved in cardiac muscle cell development-%%-GO:0006605-&&-protein targeting-%%-GO:0051533-&&-positive regulation of NFAT protein import into nucleus|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005901-&&-caveola-%%-GO:0014704-&&-intercalated disc-%%-GO:0014701-&&-junctional sarcoplasmic reticulum membrane-%%-GO:0034704-&&-calcium channel complex-%%-GO:0005635-&&-nuclear envelope-%%-GO:0005737-&&-cytoplasm-%%-GO:0030315-&&-T-tubule|molecular_function-&-1&-GO:0051018-&&-protein kinase A binding-%%-GO:0008179-&&-adenylate cyclase binding-%%-GO:0005515-&&-protein binding-%%-GO:0034237-&&-protein kinase A regulatory subunit binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0043495-&&-protein anchor-%%-GO:0032947-&&-protein complex scaffold	G:9606:AKAP6				AKAP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKAP6	0.37088763	0.30769231	14	4	FALSE	AKAP6	AKAP6	249.6428571	0	14	0	0.71729426	FALSE	0	AKAP6	16350	0.12471429
789326	taxon:9606	2.72191587	9.62E-06	175731	1902	CASP2 and RIPK1 domain containing adaptor with death domain	gene	biological_process-&-1&-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0070513-&&-death domain binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding	G:9606:CRADD				CRADD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRADD	0.36738828	0.12087912	14	4	FALSE	CRADD	CRADD	175.3571429	0	14	0	0.71301402	FALSE	0	CRADD	17318	0.09622034
789360	taxon:9606	2.72553963	4.48E-05	175667	1902	FGF1 intracellular binding protein	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0070527-&&-platelet aggregation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0012505-&&-endomembrane system-%%-GO:0016607-&&-nuclear speck-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0017134-&&-fibroblast growth factor binding	G:9606:FIBP				FIBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FIBP	0.36689982	0.17582418	14	5	FALSE	FIBP	FIBP	168.0714286	0	14	0	0.71241006	FALSE	0	FIBP	37886	0.08974359
789374	taxon:9606	2.73735623	9.54E-06	175637	1902	zinc finger MYM-type containing 4	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ZMYM4				ZMYM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMYM4	0.36531599	0.05494505	14	4	FALSE	ZMYM4	ZMYM4	168.6428571	0	14	0	0.71044063	FALSE	0	ZMYM4	15478	0.09399968
789382	taxon:9606	2.80589255	7.37E-06	175616	1902	DLG associated protein 2	gene	biological_process-&-1&-GO:0007270-&&-neuron-neuron synaptic transmission|cellular_component-&-1&-GO:0005883-&&-neurofilament-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DLGAP2				DLGAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLGAP2	0.35639284	0.38461538	14	4	FALSE	DLGAP2	DLGAP2	179.4285714	0	14	0	0.69901791	FALSE	0	DLGAP2	11180	0.13231418
789393	taxon:9606	2.7861982	4.15E-06	175585	1902	piwi like RNA-mediated gene silencing 1	gene	biological_process-&-1&-GO:0007286-&&-spermatid development-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0006417-&&-regulation of translation-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010529-&&-negative regulation of transposition-%%-GO:0034587-&&-piRNA metabolic process-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043186-&&-P granule-%%-GO:0033391-&&-chromatoid body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005845-&&-mRNA cap binding complex-%%-GO:0005844-&&-polysome-%%-GO:0097433-&&-dense body|molecular_function-&-1&-GO:0034584-&&-piRNA binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0003729-&&-mRNA binding	G:9606:PIWIL1				PIWIL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIWIL1	0.35891201	0.10989011	14	4	FALSE	PIWIL1	PIWIL1	151.2142857	0	14	0	0.7023003	FALSE	0	PIWIL1	10244	0.10127431
789441	taxon:9606	2.63147944	2.13E-05	175461	1902	component of oligomeric golgi complex 1	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0007030-&&-Golgi organization-%%-GO:0015031-&&-protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COG1				COG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG1	0.38001437	0.28571429	14	4	FALSE	COG1	COG1	233.8571429	0	14	0	0.72808676	FALSE	0	COG1	25292	0.09683724
789621	taxon:9606	2.69355601	4.68E-06	175042	1902	polypyrimidine tract binding protein 3	gene	biological_process-&-1&-GO:0033119-&&-negative regulation of RNA splicing-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0008380-&&-RNA splicing-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006397-&&-mRNA processing-%%-GO:0043249-&&-erythrocyte maturation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:PTBP3				PTBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTBP3	0.37125643	0.23076923	14	4	FALSE	PTBP3	PTBP3	231.5	0	14	0	0.71774066	FALSE	0	PTBP3	11956	0.11331375
789623	taxon:9606	2.84197259	9.43E-06	175036	1902	AKT serine/threonine kinase 3	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045793-&&-positive regulation of cell size-%%-GO:0000002-&&-mitochondrial genome maintenance-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity	G:9606:AKT3	AKT3	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04140-&&-Autophagy - animal-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05210-&&-Colorectal cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa05222-&&-Small cell lung cancer-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05223-&&-Non-small cell lung cancer-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa01524-&&-Platinum drug resistance-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05226-&&-Gastric cancer-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04931-&&-Insulin resistance-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa05160-&&-Hepatitis C-%%-hsa05224-&&-Breast cancer-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05211-&&-Renal cell carcinoma-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa05212-&&-Pancreatic cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04210-&&-Apoptosis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa05225-&&-Hepatocellular carcinoma	AKT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKT3	0.35186828	0.06593407	14	4	FALSE	AKT3	AKT3	112.2857143	0	14	0	0.69300457	FALSE	0	AKT3	12356	0.09720497
789649	taxon:9606	2.80857098	9.13E-06	174976	1902	choline/ethanolamine phosphotransferase 1	gene	biological_process-&-1&-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006646-&&-phosphatidylethanolamine biosynthetic process-%%-GO:0006657-&&-CDP-choline pathway|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004142-&&-diacylglycerol cholinephosphotransferase activity-%%-GO:0004307-&&-ethanolaminephosphotransferase activity-%%-GO:0046872-&&-metal ion binding	G:9606:CEPT1			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00440-&&-Phosphonate and phosphinate metabolism-%%-hsa00565-&&-Ether lipid metabolism	CEPT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEPT1	0.35605296	0.09090909	14	4	FALSE	CEPT1	CEPT1	138.3333333	0	13	0	0.6985715	FALSE	1	CEPT1	12872	0.10200937
789679	taxon:9606	2.70080353	1.39E-05	174909	1902	zinc finger HIT-type containing 1	gene	biological_process-&-1&-GO:0043486-&&-histone exchange-%%-GO:0031063-&&-regulation of histone deacetylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000812-&&-Swr1 complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0031491-&&-nucleosome binding-%%-GO:0005515-&&-protein binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:ZNHIT1				ZNHIT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNHIT1	0.37026018	0.14285714	14	4	FALSE	ZNHIT1	ZNHIT1	189.9285714	0	14	0	0.71653275	FALSE	0	ZNHIT1	21056	0.09552582
789736	taxon:9606	2.71766189	9.43E-06	174793	1902	SH2 domain containing 3C	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007254-&&-JNK cascade-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:SH2D3C				SH2D3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D3C	0.36796336	0.30769231	14	5	FALSE	SH2D3C	SH2D3C	197.9285714	0	14	0	0.71372302	FALSE	0	SH2D3C	15174	0.10737552
789755	taxon:9606	2.69355601	2.35E-06	174760	1902	SGK2, serine/threonine kinase 2	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0032411-&&-positive regulation of transporter activity-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0017081-&&-chloride channel regulator activity	G:9606:SGK2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	SGK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGK2	0.37125643	0.28571429	14	5	FALSE	SGK2	SGK2	250.7857143	0	14	0	0.71774066	FALSE	0	SGK2	12344	0.12339901
789813	taxon:9606	2.65857886	2.01E-05	174602	1902	regulator of G-protein signaling 19	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0006914-&&-autophagy-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0045121-&&-membrane raft-%%-GO:0005903-&&-brush border-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RGS19				RGS19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS19	0.37614081	0.15384615	14	4	FALSE	RGS19	RGS19	201.6428571	0	14	0	0.72357019	FALSE	0	RGS19	26246	0.09057901
789962	taxon:9606	2.77390893	2.42E-05	174239	1902	beta-1,4-galactosyltransferase 7	gene	biological_process-&-1&-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0006029-&&-proteoglycan metabolic process-%%-GO:0006464-&&-cellular protein modification process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0030145-&&-manganese ion binding-%%-GO:0008378-&&-galactosyltransferase activity-%%-GO:0046525-&&-xylosylprotein 4-beta-galactosyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0003831-&&-beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	G:9606:B4GALT7			KEGG-&-1&-hsa00532-&&-Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	B4GALT7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B4GALT7	0.3605021	0.02197802	14	4	FALSE	B4GALT7	B4GALT7	138.7142857	0	14	0	0.70434851	FALSE	0	B4GALT7	26622	0.08990228
790049	taxon:9606	3.06696077	1.64E-05	174001	1902	butyrophilin subfamily 2 member A1	gene	biological_process-&-1&-GO:0006629-&&-lipid metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:BTN2A1				BTN2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTN2A1	0.32605569	0	14	5	FALSE	BTN2A1	BTN2A1	31.28571429	0	14	0	0.65550654	FALSE	0	BTN2A1	9636	0.08185328
790075	taxon:9606	2.72333386	4.65E-06	173939	1902	nischarin	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0016601-&&-Rac protein signal transduction-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0048243-&&-norepinephrine secretion-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0055037-&&-recycling endosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:NISCH				NISCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NISCH	0.36719699	0.1969697	14	4	FALSE	NISCH	NISCH	203.0833333	0	13	0	0.71277769	FALSE	1	NISCH	9184	0.10984848
790116	taxon:9606	2.84606901	1.17E-05	173845	1902	ring finger protein 139	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0036503-&&-ERAD pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0031648-&&-protein destabilization-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031396-&&-regulation of protein ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060628-&&-regulation of ER to Golgi vesicle-mediated transport-%%-GO:0070613-&&-regulation of protein processing-%%-GO:2000060-&&-positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0036513-&&-Derlin-1 retrotranslocation complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0002020-&&-protease binding-%%-GO:0019787-&&-ubiquitin-like protein transferase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0016874-&&-ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF139				RNF139	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF139	0.35136182	0.20879121	14	4	FALSE	RNF139	RNF139	111.5	0	14	0	0.69232183	FALSE	0	RNF139	15904	0.09332376
790121	taxon:9606	2.96990704	4.45E-05	173836	1902	neurexophilin 2	gene	biological_process-&-1&-GO:0007218-&&-neuropeptide signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005102-&&-receptor binding	G:9606:NXPH2				NXPH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NXPH2	0.33671088	0.01098901	14	5	FALSE	NXPH2	NXPH2	45.35714286	0	14	0	0.67168216	FALSE	0	NXPH2	50534	0.08444023
790122	taxon:9606	2.82385379	7.51E-06	173828	1902	dynactin subunit 3	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0000910-&&-cytokinesis-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030496-&&-midbody-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005819-&&-spindle-%%-GO:0005869-&&-dynactin complex-%%-GO:0032154-&&-cleavage furrow|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:DCTN3				DCTN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCTN3	0.35412598	0.08791209	14	4	FALSE	DCTN3	DCTN3	114.6428571	0	14	0	0.69602437	FALSE	0	DCTN3	10740	0.08993251
790131	taxon:9606	2.71876477	2.02E-05	173803	1902	SAC1 suppressor of actin mutations 1-like (yeast)	gene	biological_process-&-1&-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0034596-&&-phosphatidylinositol phosphate 4-phosphatase activity-%%-GO:0016791-&&-phosphatase activity-%%-GO:0043812-&&-phosphatidylinositol-4-phosphate phosphatase activity-%%-GO:0034593-&&-phosphatidylinositol bisphosphate phosphatase activity-%%-GO:0004438-&&-phosphatidylinositol-3-phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:SACM1L			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	SACM1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SACM1L	0.36781409	0.21212121	14	4	FALSE	SACM1L	SACM1L	189.4166667	0	13	0	0.7135392	FALSE	1	SACM1L	23318	0.09900471
790140	taxon:9606	2.68772648	2.71E-05	173785	1902	RAB3 GTPase activating protein catalytic subunit 1	gene	biological_process-&-1&-GO:0043010-&&-camera-type eye development-%%-GO:0060325-&&-face morphogenesis-%%-GO:0061024-&&-membrane organization-%%-GO:0007420-&&-brain development-%%-GO:0034389-&&-lipid particle organization-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0021854-&&-hypothalamus development-%%-GO:0097051-&&-establishment of protein localization to endoplasmic reticulum membrane-%%-GO:1903061-&&-positive regulation of protein lipidation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1903373-&&-positive regulation of endoplasmic reticulum tubular network organization-%%-GO:0061646-&&-positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization-%%-GO:1903233-&&-regulation of calcium ion-dependent exocytosis of neurotransmitter-%%-GO:2000786-&&-positive regulation of autophagosome assembly-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0048172-&&-regulation of short-term neuronal synaptic plasticity|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0071782-&&-endoplasmic reticulum tubular network-%%-GO:0043234-&&-protein complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0098794-&&-postsynapse-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity	G:9606:RAB3GAP1	RAB3GAP1	TRUE		RAB3GAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB3GAP1	0.37206167	0.10989011	14	4	FALSE	RAB3GAP1	RAB3GAP1	205.2857143	0	14	0	0.71871225	FALSE	0	RAB3GAP1	34834	0.09859688
790141	taxon:9606	2.76571609	3.13E-05	173784	1902	RAB18, member RAS oncogene family	gene	biological_process-&-1&-GO:0071786-&&-endoplasmic reticulum tubular network organization-%%-GO:0061024-&&-membrane organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007420-&&-brain development-%%-GO:0015031-&&-protein transport-%%-GO:0034389-&&-lipid particle organization-%%-GO:1902593-&&-single-organism nuclear import-%%-GO:0001654-&&-eye development-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071782-&&-endoplasmic reticulum tubular network-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019003-&&-GDP binding	G:9606:RAB18				RAB18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB18	0.36157001	0.06593407	14	5	FALSE	RAB18	RAB18	144.5	0	14	0	0.70571399	FALSE	0	RAB18	38146	0.08978701
790145	taxon:9606	3.01276193	7.40E-06	173779	1902	SREBF chaperone	gene	biological_process-&-1&-GO:0045541-&&-negative regulation of cholesterol biosynthetic process-%%-GO:0007568-&&-aging-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0045716-&&-positive regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0032933-&&-SREBP signaling pathway-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0032868-&&-response to insulin-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0015485-&&-cholesterol binding-%%-GO:0005515-&&-protein binding	G:9606:SCAP				SCAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAP	0.33192135	0.24242424	14	5	FALSE	SCAP	SCAP	48.33333333	0	13	0	0.66453968	FALSE	1	SCAP	6624	0.10274217
790174	taxon:9606	2.92358595	6.79E-06	173712	1902	PH domain and leucine rich repeat protein phosphatase 2	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0021766-&&-hippocampus development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0042622-&&-photoreceptor outer segment membrane-%%-GO:0001917-&&-photoreceptor inner segment|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PHLPP2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	PHLPP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLPP2	0.3420457	0.25274725	14	4	FALSE	PHLPP2	PHLPP2	64.21428571	0	14	0	0.67940234	FALSE	0	PHLPP2	6598	0.09021499
790188	taxon:9606	2.82826532	6.28E-06	173687	1902	cullin associated and neddylation dissociated 2 (putative)	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0010265-&&-SCF complex assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017025-&&-TBP-class protein binding	G:9606:CAND2				CAND2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAND2	0.35357362	0.03296703	14	5	FALSE	CAND2	CAND2	116.1428571	0	14	0	0.69528911	FALSE	0	CAND2	9774	0.09078667
790217	taxon:9606	2.64046006	1.71E-06	173610	1902	WD repeat domain 43	gene	biological_process-&-1&-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0001650-&&-fibrillar center-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:WDR43			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	WDR43	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR43	0.37872188	0.3956044	14	4	FALSE	WDR43	WDR43	339.8571429	0	14	0	0.72658999	FALSE	0	WDR43	6024	0.14394627
790270	taxon:9606	2.66425083	8.69E-06	173469	1902	FRAT2, WNT signaling pathway regulator	gene	biological_process-&-1&-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:FRAT2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	FRAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FRAT2	0.37534004	0.14285714	14	4	FALSE	FRAT2	FRAT2	229	0	14	0	0.72262486	FALSE	0	FRAT2	21738	0.10318176
790290	taxon:9606	2.65416732	1.60E-05	173415	1902	translocation associated membrane protein 1	gene	biological_process-&-1&-GO:0006613-&&-cotranslational protein targeting to membrane-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:TRAM1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	TRAM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAM1	0.376766	0.17582418	14	4	FALSE	TRAM1	TRAM1	214.7142857	0	14	0	0.72430545	FALSE	0	TRAM1	27982	0.09506931
790476	taxon:9606	2.86261226	1.77E-06	172736	1902	enhancer of polycomb homolog 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006281-&&-DNA repair-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0032777-&&-Piccolo NuA4 histone acetyltransferase complex	G:9606:EPC2				EPC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPC2	0.34933128	0.67032967	14	4	FALSE	EPC2	EPC2	115.4285714	0	14	0	0.68956462	FALSE	0	EPC2	4584	0.10136832
790514	taxon:9606	2.61493619	1.19E-05	172650	1902	F-box protein 3	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXO3				FBXO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO3	0.38241851	0.34065934	14	4	FALSE	FBXO3	FBXO3	363.1428571	0	14	0	0.73084397	FALSE	0	FBXO3	15482	0.14488086
790568	taxon:9606	3.02174256	6.36E-06	172109	1902	forkhead box D3	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:FOXD3				FOXD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXD3	0.33093488	0.04395604	14	5	FALSE	FOXD3	FOXD3	75.92857143	0	14	0	0.66304291	FALSE	0	FOXD3	8610	0.15490888
790735	taxon:9606	2.76256499	3.71E-05	171353	1902	COMM domain containing 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COMMD2				COMMD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD2	0.36198243	0.41758242	14	4	FALSE	COMMD2	COMMD2	159	0	14	0	0.70623917	FALSE	0	COMMD2	25382	0.09649579
790760	taxon:9606	2.80022058	1.13E-05	171307	1902	pleckstrin homology domain containing O1	gene	biological_process-&-1&-GO:0051451-&&-myoblast migration-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007520-&&-myoblast fusion-%%-GO:0072673-&&-lamellipodium morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0036195-&&-muscle cell projection membrane-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PLEKHO1				PLEKHO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLEKHO1	0.35711472	0.13636364	14	4	FALSE	PLEKHO1	PLEKHO1	160.5	0	13	0	0.69996324	FALSE	1	PLEKHO1	11764	0.11553713
790831	taxon:9606	2.94296518	4.47E-06	171036	1902	SH3 and multiple ankyrin repeat domains 1	gene	biological_process-&-1&-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0071625-&&-vocalization behavior-%%-GO:0060013-&&-righting reflex-%%-GO:0035418-&&-protein localization to synapse-%%-GO:0060997-&&-dendritic spine morphogenesis-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0006461-&&-protein complex assembly-%%-GO:0050894-&&-determination of affect-%%-GO:0060074-&&-synapse maturation-%%-GO:0035176-&&-social behavior-%%-GO:0032232-&&-negative regulation of actin filament bundle assembly-%%-GO:0046959-&&-habituation-%%-GO:0042048-&&-olfactory behavior-%%-GO:0030534-&&-adult behavior-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0007616-&&-long-term memory-%%-GO:0008306-&&-associative learning|cellular_component-&-1&-GO:0060076-&&-excitatory synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0017146-&&-NMDA selective glutamate receptor complex-%%-GO:0043197-&&-dendritic spine-%%-GO:0030425-&&-dendrite-%%-GO:0005829-&&-cytosol-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005622-&&-intracellular-%%-GO:0008328-&&-ionotropic glutamate receptor complex-%%-GO:0016020-&&-membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0097110-&&-scaffold protein binding-%%-GO:0031877-&&-somatostatin receptor binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0071532-&&-ankyrin repeat binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0030160-&&-GKAP/Homer scaffold activity-%%-GO:0032403-&&-protein complex binding	G:9606:SHANK1			KEGG-&-1&-hsa04724-&&-Glutamatergic synapse	SHANK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHANK1	0.33979335	0.07575758	14	4	FALSE	SHANK1	SHANK1	63.33333333	0	13	0	0.67617247	FALSE	1	SHANK1	4670	0.1031746
790938	taxon:9606	2.91822908	3.60E-06	170661	1902	GINS complex subunit 2	gene	biological_process-&-1&-GO:0032508-&&-DNA duplex unwinding-%%-GO:0006271-&&-DNA strand elongation involved in DNA replication-%%-GO:1902975-&&-mitotic DNA replication initiation-%%-GO:0000727-&&-double-strand break repair via break-induced replication|cellular_component-&-1&-GO:0000811-&&-GINS complex-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043138-&&-3'-5' DNA helicase activity-%%-GO:0005515-&&-protein binding	G:9606:GINS2				GINS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GINS2	0.34267358	0.35164835	14	5	FALSE	GINS2	GINS2	76.5	0	14	0	0.68029515	FALSE	0	GINS2	4682	0.09878026
790972	taxon:9606	3.08161336	1.93E-05	170547	1902	sushi domain containing 4	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0030449-&&-regulation of complement activation-%%-GO:0006958-&&-complement activation, classical pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region	G:9606:SUSD4				SUSD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUSD4	0.32450534	0	14	5	FALSE	SUSD4	SUSD4	24.78571429	0	14	0	0.65306444	FALSE	0	SUSD4	12680	0.07981783
790986	taxon:9606	2.83929415	4.33E-05	170494	1902	tripartite motif containing 68	gene	biological_process-&-1&-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0051865-&&-protein autoubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0050681-&&-androgen receptor binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0035035-&&-histone acetyltransferase binding	G:9606:TRIM68				TRIM68	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM68	0.35220021	0.02197802	14	4	FALSE	TRIM68	TRIM68	101.0714286	0	14	0	0.69345097	FALSE	0	TRIM68	45512	0.08914286
791003	taxon:9606	2.72743028	2.99E-05	170441	1902	LDL receptor related protein 1B	gene	biological_process-&-1&-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:LRP1B				LRP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRP1B	0.36664549	0.07692308	14	4	FALSE	LRP1B	LRP1B	162.0714286	0	14	0	0.71209495	FALSE	0	LRP1B	32696	0.08807968
791016	taxon:9606	2.58657634	2.11E-05	170369	1902	glutaminyl-peptide cyclotransferase like	gene	biological_process-&-1&-GO:0017186-&&-peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016603-&&-glutaminyl-peptide cyclotransferase activity	G:9606:QPCTL				QPCTL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QPCTL	0.38661144	0.15384615	14	4	FALSE	QPCTL	QPCTL	297.5714286	0	14	0	0.73557061	FALSE	0	QPCTL	30178	0.11076219
791048	taxon:9606	2.79517882	2.76E-05	170252	1902	COMM domain containing 8	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COMMD8				COMMD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD8	0.35775886	0.36263736	14	4	FALSE	COMMD8	COMMD8	158.7857143	0	14	0	0.70080353	FALSE	0	COMMD8	26638	0.10809232
791072	taxon:9606	2.97431858	8.47E-06	170145	1902	DnaJ heat shock protein family (Hsp40) member C17	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:DNAJC17				DNAJC17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC17	0.33621146	0.0989011	14	5	FALSE	DNAJC17	DNAJC17	101.1428571	0	14	0	0.6709469	FALSE	0	DNAJC17	10180	0.18566176
791096	taxon:9606	2.73688357	9.57E-06	170063	1902	RNA binding motif protein 41	gene	biological_process-&-1&-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0032502-&&-developmental process|cellular_component-&-1&-GO:0005689-&&-U12-type spliceosomal complex|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0097157-&&-pre-mRNA intronic binding-%%-GO:0005515-&&-protein binding-%%-GO:0030626-&&-U12 snRNA binding	G:9606:RBM41				RBM41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM41	0.36537908	0.06593407	14	5	FALSE	RBM41	RBM41	179.2857143	0	14	0	0.71051941	FALSE	0	RBM41	16972	0.10140993
791100	taxon:9606	2.71088703	2.58E-05	170054	1902	kelch like family member 26	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0007286-&&-spermatid development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0008584-&&-male gonad development|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL26				KLHL26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL26	0.36888295	0.15384615	14	4	FALSE	KLHL26	KLHL26	212.5	0	14	0	0.71485216	FALSE	0	KLHL26	27994	0.10940838
791168	taxon:9606	2.7148259	6.98E-06	169836	1902	NOP2/Sun RNA methyltransferase family member 5	gene	biological_process-&-1&-GO:0070475-&&-rRNA base methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0008173-&&-RNA methyltransferase activity	G:9606:NSUN5				NSUN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSUN5	0.36834775	0.13186813	14	5	FALSE	NSUN5	NSUN5	231.7857143	0	14	0	0.71419568	FALSE	0	NSUN5	15886	0.1201973
791213	taxon:9606	2.65747597	5.16E-06	169716	1902	methylcrotonoyl-CoA carboxylase 1	gene	biological_process-&-1&-GO:0006552-&&-leucine catabolic process-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0009083-&&-branched-chain amino acid catabolic process|cellular_component-&-1&-GO:0002169-&&-3-methylcrotonyl-CoA carboxylase complex, mitochondrial-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:1905202-&&-methylcrotonoyl-CoA carboxylase complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0009374-&&-biotin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004485-&&-methylcrotonoyl-CoA carboxylase activity-%%-GO:0004075-&&-biotin carboxylase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:MCCC1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	MCCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCCC1	0.37629691	0.2967033	14	4	FALSE	MCCC1	MCCC1	260	0	14	0	0.723754	FALSE	0	MCCC1	13902	0.11473963
791223	taxon:9606	2.85883094	1.13E-05	169678	1902	brain expressed X-linked 1	gene	biological_process-&-1&-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:BEX1				BEX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BEX1	0.34979333	0.03296703	14	4	FALSE	BEX1	BEX1	105.5	0	14	0	0.69019484	FALSE	0	BEX1	14610	0.09765677
791232	taxon:9606	2.77595715	7.82E-06	169598	1902	protocadherin alpha 4	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007399-&&-nervous system development-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:PCDHA4				PCDHA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCDHA4	0.36023611	0.12087912	14	4	FALSE	PCDHA4	PCDHA4	167.4285714	0	14	0	0.70400714	FALSE	0	PCDHA4	18732	0.10860485
791264	taxon:9606	2.97274303	2.45E-06	169444	1902	CCR4-NOT transcription complex subunit 6	gene	biological_process-&-1&-GO:0035195-&&-gene silencing by miRNA-%%-GO:0000289-&&-nuclear-transcribed mRNA poly(A) tail shortening-%%-GO:0010606-&&-positive regulation of cytoplasmic mRNA processing body assembly-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2000327-&&-positive regulation of ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0070966-&&-nuclear-transcribed mRNA catabolic process, no-go decay-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043928-&&-exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030014-&&-CCR4-NOT complex|molecular_function-&-1&-GO:0004532-&&-exoribonuclease activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004535-&&-poly(A)-specific ribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0003723-&&-RNA binding	G:9606:CNOT6			KEGG-&-1&-hsa03018-&&-RNA degradation	CNOT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNOT6	0.33638965	0.36363636	14	5	FALSE	CNOT6	CNOT6	62.83333333	0	13	0	0.6712095	FALSE	1	CNOT6	3268	0.11291291
791298	taxon:9606	2.76051678	2.69E-05	169303	1902	DEAH-box helicase 37	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003676-&&-nucleic acid binding	G:9606:DHX37				DHX37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX37	0.36225101	0.10989011	14	4	FALSE	DHX37	DHX37	176.5714286	0	14	0	0.70658054	FALSE	0	DHX37	26876	0.10507709
791320	taxon:9606	2.81455806	1.00E-05	169187	1902	UTP3, small subunit processome component homolog (S. cerevisiae)	gene	biological_process-&-1&-GO:0007420-&&-brain development-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0000462-&&-maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0032040-&&-small-subunit processome-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:UTP3				UTP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UTP3	0.35529557	0.08791209	14	5	FALSE	UTP3	UTP3	131.9285714	0	14	0	0.69757366	FALSE	0	UTP3	12816	0.09747961
791338	taxon:9606	2.72301875	4.44E-06	169103	1902	ARP3 actin related protein 3 homolog B	gene	biological_process-&-1&-GO:0008150-&&-biological_process-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation|cellular_component-&-1&-GO:0005885-&&-Arp2/3 protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0042995-&&-cell projection-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function	G:9606:ACTR3B			KEGG-&-1&-hsa04530-&&-Tight junction	ACTR3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTR3B	0.36723948	0.20879121	14	5	FALSE	ACTR3B	ACTR3B	196.3571429	0	14	0	0.71283021	FALSE	0	ACTR3B	8892	0.10325393
791350	taxon:9606	2.91901686	1.05E-05	169053	1902	FK506 binding protein 10	gene	biological_process-&-1&-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0005528-&&-FK506 binding-%%-GO:0005509-&&-calcium ion binding	G:9606:FKBP10				FKBP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FKBP10	0.3425811	0.18681319	14	4	FALSE	FKBP10	FKBP10	76.71428571	0	14	0	0.68016386	FALSE	0	FKBP10	10404	0.0923913
791384	taxon:9606	2.82842288	8.70E-06	168854	1902	CREB/ATF bZIP transcription factor	gene	biological_process-&-1&-GO:0045814-&&-negative regulation of gene expression, epigenetic-%%-GO:0009615-&&-response to virus-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:CREBZF				CREBZF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREBZF	0.35355392	0.09090909	14	4	FALSE	CREBZF	CREBZF	135.5	0	13	0	0.69526285	FALSE	1	CREBZF	12880	0.10416667
791442	taxon:9606	2.93997164	6.23E-06	168627	1902	FUN14 domain containing 2	gene	biological_process-&-1&-GO:0000422-&&-mitophagy|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion	G:9606:FUNDC2				FUNDC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FUNDC2	0.34013934	0.03030303	14	4	FALSE	FUNDC2	FUNDC2	80	0	13	0	0.67667139	FALSE	1	FUNDC2	7750	0.10249785
791464	taxon:9606	2.81770915	6.24E-06	168532	1902	methyltransferase like 22	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0018022-&&-peptidyl-lysine methylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016279-&&-protein-lysine N-methyltransferase activity	G:9606:METTL22				METTL22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL22	0.35489823	0.04395604	14	4	FALSE	METTL22	METTL22	138.0714286	0	14	0	0.69704847	FALSE	0	METTL22	10400	0.10631486
791547	taxon:9606	2.55506539	1.39E-05	168113	1902	PAXIP1 associated glutamate rich protein 1	gene	biological_process-&-1&-GO:1902808-&&-positive regulation of cell cycle G1/S phase transition-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006310-&&-DNA recombination-%%-GO:0006281-&&-DNA repair-%%-GO:0033148-&&-positive regulation of intracellular estrogen receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0035097-&&-histone methyltransferase complex-%%-GO:0044666-&&-MLL3/4 complex|molecular_function-&-1&-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding	G:9606:PAGR1				PAGR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAGR1	0.39137942	0.50549451	14	4	FALSE	PAGR1	PAGR1	330.3571429	0	14	0	0.74082244	FALSE	0	PAGR1	23346	0.11428571
791554	taxon:9606	2.75421459	7.99E-06	168055	1902	ring finger protein 128, E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0031647-&&-regulation of protein stability-%%-GO:1904352-&&-positive regulation of protein catabolic process in the vacuole-%%-GO:0061462-&&-protein localization to lysosome-%%-GO:0042036-&&-negative regulation of cytokine biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005770-&&-late endosome-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:RNF128				RNF128	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF128	0.36307992	0.16666667	14	4	FALSE	RNF128	RNF128	198	0	13	0	0.7076309	FALSE	1	RNF128	13150	0.11730959
791566	taxon:9606	2.67559477	8.75E-06	167988	1902	mitotic spindle organizing protein 2B	gene	cellular_component-&-1&-GO:0008274-&&-gamma-tubulin ring complex-%%-GO:0005819-&&-spindle-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MZT2B				MZT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MZT2B	0.37374868	0.26373626	14	4	FALSE	MZT2B	MZT2B	231.2142857	0	14	0	0.72073421	FALSE	0	MZT2B	17450	0.10638648
791602	taxon:9606	2.7778478	3.30E-05	167864	1902	NLR family member X1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0032688-&&-negative regulation of interferon-beta production-%%-GO:0016032-&&-viral process-%%-GO:0050728-&&-negative regulation of inflammatory response|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:NLRX1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A	NLRX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRX1	0.35999093	0.10989011	14	4	FALSE	NLRX1	NLRX1	144.8571429	0	14	0	0.70369203	FALSE	0	NLRX1	38042	0.09668931
791604	taxon:9606	2.78210178	9.08E-06	167856	1902	Bardet-Biedl syndrome 10	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0051131-&&-chaperone-mediated protein complex assembly-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0001895-&&-retina homeostasis-%%-GO:0050896-&&-response to stimulus-%%-GO:0045494-&&-photoreceptor cell maintenance|cellular_component-&-1&-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0001103-&&-RNA polymerase II repressing transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:BBS10				BBS10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BBS10	0.35944048	0.10989011	14	4	FALSE	BBS10	BBS10	142.8571429	0	14	0	0.70298304	FALSE	0	BBS10	12970	0.09589502
791608	taxon:9606	2.73656846	6.43E-06	167839	1902	zinc finger protein 668	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF668				ZNF668	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF668	0.36542115	0.14285714	14	4	FALSE	ZNF668	ZNF668	217.6428571	0	14	0	0.71057192	FALSE	0	ZNF668	13326	0.12130886
791715	taxon:9606	2.72695762	9.04E-06	167227	1902	tripartite motif containing 56	gene	biological_process-&-1&-GO:0034340-&&-response to type I interferon-%%-GO:0051607-&&-defense response to virus-%%-GO:0032608-&&-interferon-beta production-%%-GO:0070534-&&-protein K63-linked ubiquitination-%%-GO:0032479-&&-regulation of type I interferon production|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:TRIM56				TRIM56	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM56	0.36670904	0.0989011	14	5	FALSE	TRIM56	TRIM56	199.1428571	0	14	0	0.71217373	FALSE	0	TRIM56	16250	0.10626526
791831	taxon:9606	2.86308492	9.44E-06	166630	1902	zinc finger protein 496	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0003677-&&-DNA binding	G:9606:ZNF496				ZNF496	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF496	0.34927361	0.07692308	14	5	FALSE	ZNF496	ZNF496	107.7142857	0	14	0	0.68948585	FALSE	0	ZNF496	11280	0.1002401
791906	taxon:9606	2.72522452	1.12E-04	182895	1902	angiotensinogen	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0010873-&&-positive regulation of cholesterol esterification-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0010535-&&-positive regulation of activation of JAK2 kinase activity-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0051387-&&-negative regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0003331-&&-positive regulation of extracellular matrix constituent secretion-%%-GO:1901201-&&-regulation of extracellular matrix assembly-%%-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:0002016-&&-regulation of blood volume by renin-angiotensin-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0002003-&&-angiotensin maturation-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0002018-&&-renin-angiotensin regulation of aldosterone production-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0070471-&&-uterine smooth muscle contraction-%%-GO:1903598-&&-positive regulation of gap junction assembly-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0050663-&&-cytokine secretion-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:1905010-&&-positive regulation of L-lysine import into cell-%%-GO:0002034-&&-regulation of blood vessel diameter by renin-angiotensin-%%-GO:0014061-&&-regulation of norepinephrine secretion-%%-GO:0048659-&&-smooth muscle cell proliferation-%%-GO:0003014-&&-renal system process-%%-GO:0007568-&&-aging-%%-GO:0051403-&&-stress-activated MAPK cascade-%%-GO:0007199-&&-G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger-%%-GO:0048144-&&-fibroblast proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0014824-&&-artery smooth muscle contraction-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0001822-&&-kidney development-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0034104-&&-negative regulation of tissue remodeling-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0035411-&&-catenin import into nucleus-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0035813-&&-regulation of renal sodium excretion-%%-GO:0002019-&&-regulation of renal output by angiotensin-%%-GO:0042311-&&-vasodilation-%%-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:1902828-&&-positive regulation of L-arginine import into cell-%%-GO:0010613-&&-positive regulation of cardiac muscle hypertrophy-%%-GO:0014873-&&-response to muscle activity involved in regulation of muscle adaptation-%%-GO:0003051-&&-angiotensin-mediated drinking behavior-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0051969-&&-regulation of transmission of nerve impulse|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031703-&&-type 2 angiotensin receptor binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:AGT	AGT	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04931-&&-Insulin resistance-%%-hsa04614-&&-Renin-angiotensin system-%%-hsa04934-&&-Cushing syndrome-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	AGT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGT	0.36694224	0.01515152	14	4	FALSE	AGT	AGT	180.1666667	0	13	0	0.71246258	FALSE	1	AGT	82216	0.0985348
791913	taxon:9606	2.7729636	2.27E-05	182886	1902	alpha 2-HS glycoprotein	gene	biological_process-&-1&-GO:0006953-&&-acute-phase response-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0001501-&&-skeletal system development-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0001503-&&-ossification-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006907-&&-pinocytosis-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0070168-&&-negative regulation of biomineral tissue development|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity-%%-GO:0019210-&&-kinase inhibitor activity	G:9606:AHSG	AHSG	TRUE		AHSG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHSG	0.360625	0.06593407	14	4	FALSE	AHSG	AHSG	150.1428571	0	14	0	0.70450607	FALSE	0	AHSG	23226	0.09791647
792041	taxon:9606	2.84307547	9.46E-06	182693	1902	bisphosphoglycerate mutase	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0006096-&&-glycolytic process-%%-GO:0043456-&&-regulation of pentose-phosphate shunt|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004082-&&-bisphosphoglycerate mutase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0046538-&&-2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	G:9606:BPGM			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00260-&&-Glycine, serine and threonine metabolism	BPGM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BPGM	0.35173178	0.04545455	14	4	FALSE	BPGM	BPGM	117.6666667	0	13	0	0.69282076	FALSE	1	BPGM	13042	0.10281195
792108	taxon:9606	2.86670868	1.96E-05	182596	1902	collagen type V alpha 1 chain	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0043588-&&-skin development-%%-GO:0051128-&&-regulation of cellular component organization-%%-GO:0001568-&&-blood vessel development-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:1903225-&&-negative regulation of endodermal cell differentiation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0016477-&&-cell migration-%%-GO:0045112-&&-integrin biosynthetic process-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0035989-&&-tendon development-%%-GO:0048592-&&-eye morphogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0032964-&&-collagen biosynthetic process|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005588-&&-collagen type V trimer|molecular_function-&-1&-GO:0005178-&&-integrin binding-%%-GO:0048407-&&-platelet-derived growth factor binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0046872-&&-metal ion binding-%%-GO:0043394-&&-proteoglycan binding-%%-GO:0008201-&&-heparin binding	G:9606:COL5A1			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	COL5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL5A1	0.3488321	0.12087912	14	5	FALSE	COL5A1	COL5A1	89.64285714	0	14	0	0.68888189	FALSE	0	COL5A1	19234	0.08511508
792252	taxon:9606	2.88277927	1.76E-05	165961	1902	synaptonemal complex central element protein 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007130-&&-synaptonemal complex assembly|cellular_component-&-1&-GO:0000801-&&-central element|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SYCE1				SYCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYCE1	0.34688747	0.12087912	14	4	FALSE	SYCE1	SYCE1	88.92857143	0	14	0	0.68620346	FALSE	0	SYCE1	14468	0.0908226
792261	taxon:9606	2.95226091	3.97E-05	182331	1902	CD68 molecule	gene	biological_process-&-1&-GO:0071310-&&-cellular response to organic substance-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane	G:9606:CD68			KEGG-&-1&-hsa04142-&&-Lysosome	CD68	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD68	0.33872345	0.01098901	14	4	FALSE	CD68	CD68	55.92857143	0	14	0	0.67462318	FALSE	0	CD68	50962	0.08472527
792317	taxon:9606	2.73089649	9.71E-06	165859	1902	epithelial stromal interaction 1	gene		G:9606:EPSTI1				EPSTI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPSTI1	0.36618012	0.07692308	14	4	FALSE	EPSTI1	EPSTI1	189.2142857	0	14	0	0.71151725	FALSE	0	EPSTI1	19310	0.1051731
792444	taxon:9606	2.72301875	7.90E-06	165624	1902	Williams-Beuren syndrome chromosome region 22	gene	biological_process-&-1&-GO:0070476-&&-rRNA (guanine-N7)-methylation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0031167-&&-rRNA methylation-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0016435-&&-rRNA (guanine) methyltransferase activity-%%-GO:0008168-&&-methyltransferase activity	G:9606:WBSCR22				WBSCR22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WBSCR22	0.36723948	0.06593407	14	4	FALSE	WBSCR22	WBSCR22	198.8571429	0	14	0	0.71283021	FALSE	0	WBSCR22	14260	0.10660522
792460	taxon:9606	2.86324248	1.65E-05	181982	1902	cytochrome b-245 alpha chain	gene	biological_process-&-1&-GO:0070555-&&-response to interleukin-1-%%-GO:1900426-&&-positive regulation of defense response to bacterium-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0032930-&&-positive regulation of superoxide anion generation-%%-GO:0045087-&&-innate immune response-%%-GO:0070257-&&-positive regulation of mucus secretion-%%-GO:0042554-&&-superoxide anion generation-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0006954-&&-inflammatory response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045730-&&-respiratory burst-%%-GO:1904385-&&-cellular response to angiotensin-%%-GO:0051279-&&-regulation of release of sequestered calcium ion into cytosol-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0017004-&&-cytochrome complex assembly-%%-GO:0042493-&&-response to drug-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0034137-&&-positive regulation of toll-like receptor 2 signaling pathway-%%-GO:1904044-&&-response to aldosterone-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0071480-&&-cellular response to gamma radiation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0001666-&&-response to hypoxia-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:1904845-&&-cellular response to L-glutamine-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0003106-&&-negative regulation of glomerular filtration by angiotensin-%%-GO:0014895-&&-smooth muscle hypertrophy-%%-GO:0050665-&&-hydrogen peroxide biosynthetic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0014823-&&-response to activity-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0043020-&&-NADPH oxidase complex-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005739-&&-mitochondrion-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0097038-&&-perinuclear endoplasmic reticulum-%%-GO:0001725-&&-stress fiber-%%-GO:0030425-&&-dendrite-%%-GO:0030141-&&-secretory granule-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0020037-&&-heme binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CYBA	CYBA	TRUE	KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04145-&&-Phagosome-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation	CYBA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYBA	0.34925439	0.1978022	14	4	FALSE	CYBA	CYBA	94.28571429	0	14	0	0.68945959	FALSE	0	CYBA	18818	0.09055877
792464	taxon:9606	2.7099417	6.66E-06	181978	1902	cylicin 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0033150-&&-cytoskeletal calyx|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton	G:9606:CYLC2				CYLC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYLC2	0.36901163	0.07692308	14	4	FALSE	CYLC2	CYLC2	199.9285714	0	14	0	0.71500972	FALSE	0	CYLC2	18200	0.10290869
792488	taxon:9606	2.79754215	5.63E-05	181940	1902	complement C1q B chain	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0048839-&&-inner ear development-%%-GO:0006956-&&-complement activation-%%-GO:0006508-&&-proteolysis-%%-GO:0006958-&&-complement activation, classical pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005602-&&-complement component C1 complex-%%-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:C1QB			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05020-&&-Prion diseases-%%-hsa05133-&&-Pertussis-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	C1QB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QB	0.35745663	0.05494505	14	4	FALSE	C1QB	C1QB	138.0714286	0	14	0	0.70040964	FALSE	0	C1QB	45700	0.0985151
792494	taxon:9606	2.64408382	1.00E-05	181918	1902	VPS51, GARP complex subunit	gene	biological_process-&-1&-GO:0048193-&&-Golgi vesicle transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0015031-&&-protein transport-%%-GO:0007030-&&-Golgi organization-%%-GO:0007041-&&-lysosomal transport-%%-GO:0006869-&&-lipid transport-%%-GO:0032456-&&-endocytic recycling-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:1990745-&&-EARP complex-%%-GO:0005730-&&-nucleolus-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0016020-&&-membrane-%%-GO:0000938-&&-GARP complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0055037-&&-recycling endosome-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003674-&&-molecular_function	G:9606:VPS51				VPS51	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS51	0.37820284	0.12087912	14	4	FALSE	VPS51	VPS51	237.0714286	0	14	0	0.72598603	FALSE	0	VPS51	20476	0.10132037
792498	taxon:9606	2.90263116	1.45E-05	181905	1902	metallophosphoesterase domain containing 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0016787-&&-hydrolase activity	G:9606:MPPED1				MPPED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPPED1	0.34451501	0.07692308	14	5	FALSE	MPPED1	MPPED1	78.28571429	0	14	0	0.68289481	FALSE	0	MPPED1	14224	0.09072011
792506	taxon:9606	2.72191587	8.36E-06	181889	1902	calcium voltage-gated channel subunit alpha1 C	gene	biological_process-&-1&-GO:0002520-&&-immune system development-%%-GO:0043010-&&-camera-type eye development-%%-GO:0086012-&&-membrane depolarization during cardiac muscle cell action potential-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007507-&&-heart development-%%-GO:0035585-&&-calcium-mediated signaling using extracellular calcium source-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0061577-&&-calcium ion transmembrane transport via high voltage-gated calcium channel-%%-GO:0060402-&&-calcium ion transport into cytosol-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:0098911-&&-regulation of ventricular cardiac muscle cell action potential-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0061337-&&-cardiac conduction-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0086045-&&-membrane depolarization during AV node cell action potential-%%-GO:0098912-&&-membrane depolarization during atrial cardiac muscle cell action potential-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:1990454-&&-L-type voltage-gated calcium channel complex-%%-GO:0005891-&&-voltage-gated calcium channel complex-%%-GO:0030018-&&-Z disc|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0008331-&&-high voltage-gated calcium channel activity-%%-GO:0086007-&&-voltage-gated calcium channel activity involved in cardiac muscle cell action potential-%%-GO:0005245-&&-voltage-gated calcium channel activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0051393-&&-alpha-actinin binding-%%-GO:0086056-&&-voltage-gated calcium channel activity involved in AV node cell action potential	G:9606:CACNA1C			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa05010-&&-Alzheimer disease-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04930-&&-Type II diabetes mellitus-%%-hsa04924-&&-Renin secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04720-&&-Long-term potentiation-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04911-&&-Insulin secretion-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04713-&&-Circadian entrainment-%%-hsa04022-&&-cGMP-PKG signaling pathway	CACNA1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACNA1C	0.36738828	0.12087912	14	4	FALSE	CACNA1C	CACNA1C	220.2857143	0	14	0	0.71301402	FALSE	0	CACNA1C	15608	0.11969532
792519	taxon:9606	2.77532693	8.27E-06	181856	1902	calcium/calmodulin dependent protein kinase IV	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006954-&&-inflammatory response-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0007616-&&-long-term memory-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0045670-&&-regulation of osteoclast differentiation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033081-&&-regulation of T cell differentiation in thymus-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0002372-&&-myeloid dendritic cell cytokine production|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004683-&&-calmodulin-dependent protein kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0009931-&&-calcium-dependent protein serine/threonine kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:CAMK4			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04720-&&-Long-term potentiation-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05034-&&-Alcoholism-%%-hsa04921-&&-Oxytocin signaling pathway	CAMK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK4	0.36031791	0.10606061	14	4	FALSE	CAMK4	CAMK4	179.1666667	0	13	0	0.70411218	FALSE	1	CAMK4	10862	0.11543011
792566	taxon:9606	2.76130455	7.55E-06	181806	1902	carbonyl reductase 3	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0042376-&&-phylloquinone catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0050890-&&-cognition|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0070402-&&-NADPH binding-%%-GO:0004090-&&-carbonyl reductase (NADPH) activity-%%-GO:0005515-&&-protein binding-%%-GO:0000253-&&-3-keto sterol reductase activity	G:9606:CBR3			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	CBR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBR3	0.36214767	0.14285714	14	4	FALSE	CBR3	CBR3	156.6428571	0	14	0	0.70644924	FALSE	0	CBR3	11580	0.09554335
792594	taxon:9606	2.82322357	1.47E-05	181744	1902	heparin binding EGF like growth factor	gene	biological_process-&-1&-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0051549-&&-positive regulation of keratinocyte migration-%%-GO:0035313-&&-wound healing, spreading of epidermal cells-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0090303-&&-positive regulation of wound healing-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0051545-&&-negative regulation of elastin biosynthetic process-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0007517-&&-muscle organ development-%%-GO:0060326-&&-cell chemotaxis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0008201-&&-heparin binding	G:9606:HBEGF			KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa01522-&&-Endocrine resistance-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa04915-&&-Estrogen signaling pathway	HBEGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBEGF	0.35420503	0.15151515	14	5	FALSE	HBEGF	HBEGF	123.25	0	13	0	0.6961294	FALSE	1	HBEGF	14708	0.09729908
792641	taxon:9606	2.70253663	1.95E-05	181656	1902	CD36 molecule	gene	biological_process-&-1&-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0071726-&&-cellular response to diacyl bacterial lipopeptide-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0034197-&&-triglyceride transport-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0034381-&&-plasma lipoprotein particle clearance-%%-GO:0007155-&&-cell adhesion-%%-GO:0050909-&&-sensory perception of taste-%%-GO:0030299-&&-intestinal cholesterol absorption-%%-GO:1900227-&&-positive regulation of NLRP3 inflammasome complex assembly-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0030194-&&-positive regulation of blood coagulation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0044539-&&-long-chain fatty acid import-%%-GO:0010886-&&-positive regulation of cholesterol storage-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0050702-&&-interleukin-1 beta secretion-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0038124-&&-toll-like receptor TLR6:TLR2 signaling pathway-%%-GO:1990000-&&-amyloid fibril formation-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:0033993-&&-response to lipid-%%-GO:0035634-&&-response to stilbenoid-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0007596-&&-blood coagulation-%%-GO:0070508-&&-cholesterol import-%%-GO:0002576-&&-platelet degranulation-%%-GO:0050892-&&-intestinal absorption-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0070542-&&-response to fatty acid-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:2000121-&&-regulation of removal of superoxide radicals-%%-GO:0031623-&&-receptor internalization-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0042953-&&-lipoprotein transport-%%-GO:0019934-&&-cGMP-mediated signaling-%%-GO:0070543-&&-response to linoleic acid-%%-GO:2000334-&&-positive regulation of blood microparticle formation-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0030301-&&-cholesterol transport-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0060907-&&-positive regulation of macrophage cytokine production-%%-GO:0042992-&&-negative regulation of transcription factor import into nucleus-%%-GO:0055096-&&-low-density lipoprotein particle mediated signaling-%%-GO:0019915-&&-lipid storage-%%-GO:0071223-&&-cellular response to lipoteichoic acid|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0031526-&&-brush border membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0031092-&&-platelet alpha granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0071813-&&-lipoprotein particle binding-%%-GO:0070053-&&-thrombospondin receptor activity-%%-GO:0008035-&&-high-density lipoprotein particle binding-%%-GO:0070892-&&-lipoteichoic acid receptor activity-%%-GO:0008289-&&-lipid binding-%%-GO:0050431-&&-transforming growth factor beta binding	G:9606:CD36	CD36	TRUE	KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa04979-&&-Cholesterol metabolism-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04145-&&-Phagosome-%%-hsa04931-&&-Insulin resistance-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa05144-&&-Malaria	CD36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD36	0.37002274	0.1978022	14	5	FALSE	CD36	CD36	193.8571429	0	14	0	0.71624389	FALSE	0	CD36	25786	0.09838206
792649	taxon:9606	2.73215692	3.75E-05	165258	1902	suppressor of cytokine signaling 4	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0040008-&&-regulation of growth-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:SOCS4			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS4	0.36601119	0.12087912	14	4	FALSE	SOCS4	SOCS4	173.3571429	0	14	0	0.71130718	FALSE	0	SOCS4	34778	0.09654018
792815	taxon:9606	3.00252088	2.41E-05	181326	1902	elastin	gene	biological_process-&-1&-GO:0007585-&&-respiratory gaseous exchange-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0008283-&&-cell proliferation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0071953-&&-elastic fiber|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding	G:9606:ELN			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	ELN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELN	0.33305347	0.03296703	14	4	FALSE	ELN	ELN	34.42857143	0	14	0	0.66624652	FALSE	0	ELN	17924	0.08178054
792896	taxon:9606	2.97904522	3.44E-05	181206	1902	coagulation factor VIII	gene	biological_process-&-1&-GO:0006953-&&-acute-phase response-%%-GO:0030168-&&-platelet activation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006508-&&-proteolysis-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0007597-&&-blood coagulation, intrinsic pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0005515-&&-protein binding	G:9606:F8			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F8	0.33567802	0.13186813	14	4	FALSE	F8	F8	49.57142857	0	14	0	0.67015913	FALSE	0	F8	33618	0.0903977
792932	taxon:9606	2.95005514	3.32E-06	181117	1902	Fanconi anemia complementation group E	gene	biological_process-&-1&-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:FANCE			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCE	0.33897671	0.36363636	14	4	FALSE	FANCE	FANCE	69.25	0	13	0	0.67499081	FALSE	1	FANCE	4366	0.11241883
792947	taxon:9606	2.83976682	2.95E-05	181097	1902	EGF containing fibulin like extracellular matrix protein 1	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043010-&&-camera-type eye development-%%-GO:0048050-&&-post-embryonic eye morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0048048-&&-embryonic eye morphogenesis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005006-&&-epidermal growth factor-activated receptor activity-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:EFEMP1				EFEMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFEMP1	0.35214159	0.03296703	14	4	FALSE	EFEMP1	EFEMP1	99	0	14	0	0.6933722	FALSE	0	EFEMP1	36892	0.08917239
793010	taxon:9606	2.77375138	1.73E-05	164530	1902	carnosine N-methyltransferase 1	gene	biological_process-&-1&-GO:0006548-&&-histidine catabolic process-%%-GO:0032259-&&-methylation-%%-GO:0035498-&&-carnosine metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0030735-&&-carnosine N-methyltransferase activity	G:9606:CARNMT1			KEGG-&-1&-hsa00340-&&-Histidine metabolism	CARNMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARNMT1	0.36052258	0.06593407	14	5	FALSE	CARNMT1	CARNMT1	135.4285714	0	14	0	0.70437477	FALSE	0	CARNMT1	18608	0.08681672
793041	taxon:9606	2.89223255	6.97E-06	180848	1902	glutamate metabotropic receptor 5	gene	biological_process-&-1&-GO:0007196-&&-adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0060078-&&-regulation of postsynaptic membrane potential-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007612-&&-learning-%%-GO:0007206-&&-phospholipase C-activating G-protein coupled glutamate receptor signaling pathway-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0007626-&&-locomotory behavior-%%-GO:0099566-&&-regulation of postsynaptic cytosolic calcium ion concentration-%%-GO:0050890-&&-cognition-%%-GO:0007216-&&-G-protein coupled glutamate receptor signaling pathway-%%-GO:0099565-&&-chemical synaptic transmission, postsynaptic|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0042734-&&-presynaptic membrane|molecular_function-&-1&-GO:0099530-&&-G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential-%%-GO:0008066-&&-glutamate receptor activity-%%-GO:0099583-&&-neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:GRM5			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRM5	0.34575366	0.10606061	14	4	FALSE	GRM5	GRM5	104.25	0	13	0	0.68462791	FALSE	1	GRM5	9376	0.1214425
793071	taxon:9606	2.69465889	9.06E-06	164421	1902	transcription elongation factor A like 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:TCEAL2				TCEAL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEAL2	0.37110448	0.12087912	14	5	FALSE	TCEAL2	TCEAL2	196.5714286	0	14	0	0.71755685	FALSE	0	TCEAL2	14266	0.0964549
793101	taxon:9606	2.85221364	6.76E-06	180731	1902	guanylate binding protein 1	gene	biological_process-&-1&-GO:1903077-&&-negative regulation of protein localization to plasma membrane-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0051607-&&-defense response to virus-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:1900041-&&-negative regulation of interleukin-2 secretion-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:1903076-&&-regulation of protein localization to plasma membrane-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0030507-&&-spectrin binding-%%-GO:0003779-&&-actin binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019955-&&-cytokine binding-%%-GO:0051879-&&-Hsp90 protein binding	G:9606:GBP1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	GBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBP1	0.35060487	0.13636364	14	4	FALSE	GBP1	GBP1	122.6666667	0	13	0	0.69129773	FALSE	1	GBP1	7742	0.11223242
793112	taxon:9606	2.66236017	6.23E-06	180718	1902	biogenesis of lysosomal organelles complex 1 subunit 1	gene	biological_process-&-1&-GO:0032438-&&-melanosome organization-%%-GO:0048490-&&-anterograde synaptic vesicle transport-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0009060-&&-aerobic respiration-%%-GO:0060155-&&-platelet dense granule organization-%%-GO:0016197-&&-endosomal transport-%%-GO:0018394-&&-peptidyl-lysine acetylation-%%-GO:0032418-&&-lysosome localization-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0099078-&&-BORC complex-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BLOC1S1				BLOC1S1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLOC1S1	0.37560658	0.15151515	14	4	FALSE	BLOC1S1	BLOC1S1	251.4166667	0	13	0	0.72293997	FALSE	1	BLOC1S1	13710	0.11408685
793137	taxon:9606	2.90956357	1.73E-05	180670	1902	gap junction protein beta 2	gene	biological_process-&-1&-GO:0002931-&&-response to ischemia-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0055085-&&-transmembrane transport-%%-GO:0044752-&&-response to human chorionic gonadotropin-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0048839-&&-inner ear development-%%-GO:0030539-&&-male genitalia development-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0034599-&&-cellular response to oxidative stress-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0046677-&&-response to antibiotic-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0046697-&&-decidualization-%%-GO:0016264-&&-gap junction assembly-%%-GO:0006810-&&-transport-%%-GO:0032570-&&-response to progesterone|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0097449-&&-astrocyte projection-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005922-&&-connexin complex-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0044297-&&-cell body|molecular_function-&-1&-GO:0005243-&&-gap junction channel activity	G:9606:GJB2				GJB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJB2	0.34369416	0.04395604	14	5	FALSE	GJB2	GJB2	67.92857143	0	14	0	0.6817394	FALSE	0	GJB2	14008	0.08430181
793138	taxon:9606	2.95052781	2.31E-05	180667	1902	glycerol kinase	gene	biological_process-&-1&-GO:0046167-&&-glycerol-3-phosphate biosynthetic process-%%-GO:0006071-&&-glycerol metabolic process-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0019563-&&-glycerol catabolic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0019432-&&-triglyceride biosynthetic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0004370-&&-glycerol kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:GK			KEGG-&-1&-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa03320-&&-PPAR signaling pathway	GK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GK	0.33892241	0.02197802	14	4	FALSE	GK	GK	46.71428571	0	14	0	0.67491203	FALSE	0	GK	14820	0.07944732
793139	taxon:9606	2.72522452	5.70E-06	180661	1902	galactosidase beta 1	gene	biological_process-&-1&-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0042340-&&-keratan sulfate catabolic process-%%-GO:0044262-&&-cellular carbohydrate metabolic process-%%-GO:0019388-&&-galactose catabolic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005773-&&-vacuole-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0016936-&&-galactoside binding-%%-GO:0004565-&&-beta-galactosidase activity-%%-GO:0004308-&&-exo-alpha-sialidase activity-%%-GO:0005515-&&-protein binding	G:9606:GLB1			KEGG-&-1&-hsa00604-&&-Glycosphingolipid biosynthesis - ganglio series-%%-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00511-&&-Other glycan degradation-%%-hsa00600-&&-Sphingolipid metabolism-%%-hsa04142-&&-Lysosome-%%-hsa00531-&&-Glycosaminoglycan degradation	GLB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLB1	0.36694224	0.15384615	14	4	FALSE	GLB1	GLB1	187.2142857	0	14	0	0.71246258	FALSE	0	GLB1	12418	0.10299095
793142	taxon:9606	2.68079408	1.54E-05	180654	1902	glutamate-cysteine ligase modifier subunit	gene	biological_process-&-1&-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0014823-&&-response to activity-%%-GO:0035229-&&-positive regulation of glutamate-cysteine ligase activity-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0006534-&&-cysteine metabolic process-%%-GO:0035733-&&-hepatic stellate cell activation-%%-GO:0044752-&&-response to human chorionic gonadotropin-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0006536-&&-glutamate metabolic process-%%-GO:0051409-&&-response to nitrosative stress-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0097069-&&-cellular response to thyroxine stimulus-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0006750-&&-glutathione biosynthetic process-%%-GO:0007568-&&-aging-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0051900-&&-regulation of mitochondrial depolarization-%%-GO:0042493-&&-response to drug-%%-GO:0007584-&&-response to nutrient-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0000096-&&-sulfur amino acid metabolic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0017109-&&-glutamate-cysteine ligase complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0030234-&&-enzyme regulator activity-%%-GO:0004357-&&-glutamate-cysteine ligase activity-%%-GO:0035226-&&-glutamate-cysteine ligase catalytic subunit binding	G:9606:GCLM			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00480-&&-Glutathione metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04216-&&-Ferroptosis	GCLM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCLM	0.3730238	0.04395604	14	4	FALSE	GCLM	GCLM	206.2142857	0	14	0	0.71986765	FALSE	0	GCLM	23910	0.09786598
793144	taxon:9606	2.65684575	3.66E-05	180650	1902	golgi glycoprotein 1	gene	biological_process-&-1&-GO:0032330-&&-regulation of chondrocyte differentiation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0010955-&&-negative regulation of protein processing-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060349-&&-bone morphogenesis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0017134-&&-fibroblast growth factor binding	G:9606:GLG1			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	GLG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLG1	0.37638617	0.04395604	14	4	FALSE	GLG1	GLG1	256.7857143	0	14	0	0.72385904	FALSE	0	GLG1	40468	0.11247335
793149	taxon:9606	2.81061919	1.34E-05	180639	1902	glutaredoxin	gene	biological_process-&-1&-GO:0080058-&&-protein deglutathionylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0045838-&&-positive regulation of membrane potential-%%-GO:2000651-&&-positive regulation of sodium ion transmembrane transporter activity-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015038-&&-glutathione disulfide oxidoreductase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0097573-&&-glutathione oxidoreductase activity-%%-GO:0047485-&&-protein N-terminus binding	G:9606:GLRX				GLRX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLRX	0.35579349	0.10989011	14	4	FALSE	GLRX	GLRX	124.6428571	0	14	0	0.69823013	FALSE	0	GLRX	17598	0.09294256
793165	taxon:9606	2.85694029	3.13E-06	180610	1902	GNAS complex locus	gene	biological_process-&-1&-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0060348-&&-bone development-%%-GO:0007606-&&-sensory perception of chemical stimulus-%%-GO:0070527-&&-platelet aggregation-%%-GO:0050890-&&-cognition-%%-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:2000828-&&-regulation of parathyroid hormone secretion-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0071514-&&-genetic imprinting-%%-GO:0006306-&&-DNA methylation-%%-GO:0040032-&&-post-embryonic body morphogenesis-%%-GO:0048589-&&-developmental growth-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0051216-&&-cartilage development-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0060789-&&-hair follicle placode formation-%%-GO:0001958-&&-endochondral ossification-%%-GO:0042493-&&-response to drug-%%-GO:0001894-&&-tissue homeostasis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0051430-&&-corticotropin-releasing hormone receptor 1 binding-%%-GO:0005515-&&-protein binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031698-&&-beta-2 adrenergic receptor binding-%%-GO:0031852-&&-mu-type opioid receptor binding-%%-GO:0031748-&&-D1 dopamine receptor binding-%%-GO:0035255-&&-ionotropic glutamate receptor binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005159-&&-insulin-like growth factor receptor binding	G:9606:GNAS	GNAS	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04730-&&-Long-term depression-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa05146-&&-Amoebiasis-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04976-&&-Bile secretion-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04540-&&-Gap junction-%%-hsa04911-&&-Insulin secretion-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04970-&&-Salivary secretion	GNAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAS	0.35002482	0.01515152	14	4	FALSE	GNAS	GNAS	112.6666667	0	13	0	0.69050995	FALSE	1	GNAS	6004	0.10510652
793372	taxon:9606	2.94784938	1.66E-05	180226	1902	integrin subunit alpha M	gene	biological_process-&-1&-GO:0010668-&&-ectodermal cell differentiation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0007155-&&-cell adhesion-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0034142-&&-toll-like receptor 4 signaling pathway|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0070821-&&-tertiary granule membrane|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ITGAM			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04145-&&-Phagosome-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05134-&&-Legionellosis-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05146-&&-Amoebiasis-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05133-&&-Pertussis	ITGAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGAM	0.33923036	0.06593407	14	4	FALSE	ITGAM	ITGAM	57.21428571	0	14	0	0.67535844	FALSE	0	ITGAM	12824	0.08490163
787055	taxon:9606	2.86324248	5.46E-06	180153	1902	SP110 nuclear body protein	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016032-&&-viral process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004871-&&-signal transducer activity	G:9606:SP110				SP110	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP110	0.34925439	0.06410256	13	5	FALSE	SP110	SP110	134.9230769	0	13	0	0.68945959	FALSE	0	SP110	9586	0.12431509
787122	taxon:9606	2.88041594	3.98E-05	180024	1902	interleukin 13 receptor subunit alpha 2	gene	biological_process-&-1&-GO:0002638-&&-negative regulation of immunoglobulin production-%%-GO:0016064-&&-immunoglobulin mediated immune response-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0043305-&&-negative regulation of mast cell degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004896-&&-cytokine receptor activity-%%-GO:0004871-&&-signal transducer activity	G:9606:IL13RA2			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL13RA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL13RA2	0.34717208	0.03846154	13	4	FALSE	IL13RA2	IL13RA2	95.61538462	0	13	0	0.68659734	FALSE	0	IL13RA2	48018	0.10248112
787144	taxon:9606	2.8290531	1.39E-05	163606	1902	anterior gradient 3, protein disulphide isomerase family member	gene	biological_process-&-1&-GO:0030154-&&-cell differentiation-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0002162-&&-dystroglycan binding-%%-GO:0005515-&&-protein binding	G:9606:AGR3				AGR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGR3	0.35347516	0.06410256	13	4	FALSE	AGR3	AGR3	115.0769231	0	13	0	0.69515782	FALSE	0	AGR3	20658	0.09599278
787232	taxon:9606	2.99763668	3.85E-06	163443	1902	death effector domain containing 2	gene	biological_process-&-1&-GO:0019725-&&-cellular homeostasis-%%-GO:0016075-&&-rRNA catabolic process-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0006396-&&-RNA processing-%%-GO:0008625-&&-extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0030262-&&-apoptotic nuclear changes-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:DEDD2				DEDD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEDD2	0.33359613	0.16363636	13	4	FALSE	DEDD2	DEDD2	58.54545455	0	12	0	0.66706055	FALSE	1	DEDD2	3712	0.11493635
787234	taxon:9606	2.84858988	9.73E-06	163439	1902	zinc finger protein 579	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF579				ZNF579	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF579	0.35105088	0.01282051	13	5	FALSE	ZNF579	ZNF579	101	0	13	0	0.69190169	FALSE	0	ZNF579	11328	0.09063696
787255	taxon:9606	2.6584213	3.51E-05	179795	1902	STT3A, catalytic subunit of the oligosaccharyltransferase complex	gene	biological_process-&-1&-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0043686-&&-co-translational protein modification-%%-GO:0043687-&&-post-translational protein modification|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0005515-&&-protein binding	G:9606:STT3A			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	STT3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STT3A	0.3761631	0.1025641	13	4	FALSE	STT3A	STT3A	256.4615385	0	13	0	0.72359645	FALSE	0	STT3A	39164	0.1125951
787295	taxon:9606	2.84291791	5.03E-06	179718	1902	ketohexokinase	gene	biological_process-&-1&-GO:0010043-&&-response to zinc ion-%%-GO:0061624-&&-fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0009750-&&-response to fructose-%%-GO:0009749-&&-response to glucose-%%-GO:0009744-&&-response to sucrose-%%-GO:0032868-&&-response to insulin|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004454-&&-ketohexokinase activity	G:9606:KHK			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01100-&&-Metabolic pathways	KHK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KHK	0.35175127	0.10909091	13	4	FALSE	KHK	KHK	136	0	12	0	0.69284701	FALSE	1	KHK	6738	0.11680488
787406	taxon:9606	2.8408697	3.98E-05	163098	1902	Fanconi anemia core complex associated protein 20	gene	biological_process-&-1&-GO:0019985-&&-translesion synthesis-%%-GO:0036297-&&-interstrand cross-link repair-%%-GO:0006974-&&-cellular response to DNA damage stimulus|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005694-&&-chromosome-%%-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0043130-&&-ubiquitin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0031593-&&-polyubiquitin binding-%%-GO:0070530-&&-K63-linked polyubiquitin binding-%%-GO:0005515-&&-protein binding	G:9606:FAAP20				FAAP20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAAP20	0.35200488	0.26923077	13	4	FALSE	FAAP20	FAAP20	114.9230769	0	13	0	0.69318838	FALSE	0	FAAP20	47126	0.09732725
787433	taxon:9606	2.68426028	6.35E-06	179447	1902	leucine zipper and EF-hand containing transmembrane protein 1	gene	biological_process-&-1&-GO:0042407-&&-cristae formation-%%-GO:0006875-&&-cellular metal ion homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0043022-&&-ribosome binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:LETM1				LETM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LETM1	0.37254211	0.12820513	13	4	FALSE	LETM1	LETM1	240.6923077	0	13	0	0.71928995	FALSE	0	LETM1	18058	0.11326497
787457	taxon:9606	2.85835828	2.49E-04	179397	1902	meprin A subunit beta	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0007586-&&-digestion-%%-GO:0006954-&&-inflammatory response-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:MEP1B			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	MEP1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEP1B	0.34985117	0.10909091	13	4	FALSE	MEP1B	MEP1B	109.3636364	0	12	0	0.69027362	FALSE	1	MEP1B	261492	0.1017842
787522	taxon:9606	2.76807941	5.11E-06	162895	1902	F-box protein 45	gene	biological_process-&-1&-GO:0021960-&&-anterior commissure morphogenesis-%%-GO:0001764-&&-neuron migration-%%-GO:0021799-&&-cerebral cortex radially oriented cell migration-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0021800-&&-cerebral cortex tangential migration-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0060386-&&-synapse assembly involved in innervation-%%-GO:0021957-&&-corticospinal tract morphogenesis|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBXO45				FBXO45	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO45	0.36126131	0.17948718	13	5	FALSE	FBXO45	FBXO45	169.3076923	0	13	0	0.7053201	FALSE	0	FBXO45	9528	0.1062041
787531	taxon:9606	2.99747912	4.09E-05	179242	1902	opioid receptor kappa 1	gene	biological_process-&-1&-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0044849-&&-estrous cycle-%%-GO:2000505-&&-regulation of energy homeostasis-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:1903937-&&-response to acrylamide-%%-GO:0043627-&&-response to estrogen-%%-GO:1990708-&&-conditioned place preference-%%-GO:0032868-&&-response to insulin-%%-GO:0033603-&&-positive regulation of dopamine secretion-%%-GO:0050951-&&-sensory perception of temperature stimulus-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0009314-&&-response to radiation-%%-GO:0043278-&&-response to morphine-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0046877-&&-regulation of saliva secretion-%%-GO:0045471-&&-response to ethanol-%%-GO:0007626-&&-locomotory behavior-%%-GO:0033685-&&-negative regulation of luteinizing hormone secretion-%%-GO:0040017-&&-positive regulation of locomotion-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0006955-&&-immune response-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0042755-&&-eating behavior-%%-GO:0051607-&&-defense response to virus-%%-GO:0038003-&&-opioid receptor signaling pathway-%%-GO:0007600-&&-sensory perception-%%-GO:0048148-&&-behavioral response to cocaine-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:1903715-&&-regulation of aerobic respiration-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0042711-&&-maternal behavior-%%-GO:0007610-&&-behavior-%%-GO:0031635-&&-adenylate cyclase-inhibiting opioid receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0043204-&&-perikaryon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030425-&&-dendrite-%%-GO:0043679-&&-axon terminus|molecular_function-&-1&-GO:0042923-&&-neuropeptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0004985-&&-opioid receptor activity-%%-GO:0038048-&&-dynorphin receptor activity	G:9606:OPRK1			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	OPRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPRK1	0.33361367	0.14102564	13	4	FALSE	OPRK1	OPRK1	53.23076923	0	13	0	0.66708681	FALSE	0	OPRK1	65282	0.09717339
787691	taxon:9606	2.72207342	1.30E-07	178937	1902	PLAG1 like zinc finger 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0030154-&&-cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest|cellular_component-&-1&-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:PLAGL1				PLAGL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLAGL1	0.36736702	0.76363636	13	4	FALSE	PLAGL1	PLAGL1	326.9090909	0	12	0	0.71298776	FALSE	1	PLAGL1	622	0.174073
787710	taxon:9606	2.97715456	1.79E-05	178904	1902	phospholipid transfer protein	gene	biological_process-&-1&-GO:0010189-&&-vitamin E biosynthetic process-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0006869-&&-lipid transport-%%-GO:0034375-&&-high-density lipoprotein particle remodeling|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008289-&&-lipid binding	G:9606:PLTP			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa03320-&&-PPAR signaling pathway	PLTP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLTP	0.33589119	0.03846154	13	4	FALSE	PLTP	PLTP	46.84615385	0	13	0	0.67047424	FALSE	0	PLTP	13324	0.08910009
787829	taxon:9606	2.84039704	4.97E-06	178740	1902	mitogen-activated protein kinase 4	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0007049-&&-cell cycle-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004707-&&-MAP kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAPK4			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	MAPK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAPK4	0.35206346	0.09090909	13	5	FALSE	MAPK4	MAPK4	135.1818182	0	12	0	0.69326716	FALSE	1	MAPK4	7240	0.11446667
787864	taxon:9606	2.92090752	2.62E-05	178687	1902	proteinase 3	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006508-&&-proteolysis-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:0007596-&&-blood coagulation-%%-GO:0097029-&&-mature conventional dendritic cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0031012-&&-extracellular matrix-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008236-&&-serine-type peptidase activity	G:9606:PRTN3				PRTN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRTN3	0.34235935	0.03636364	13	5	FALSE	PRTN3	PRTN3	79.54545455	0	12	0	0.67984875	FALSE	1	PRTN3	21438	0.10535259
787915	taxon:9606	2.9453285	1.76E-05	178616	1902	prostaglandin I2 (prostacyclin) receptor (IP)	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0016501-&&-prostacyclin receptor activity	G:9606:PTGIR			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04611-&&-Platelet activation-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	PTGIR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGIR	0.3395207	0.12727273	13	5	FALSE	PTGIR	PTGIR	74.27272727	0	12	0	0.67577858	FALSE	1	PTGIR	15806	0.1085044
787952	taxon:9606	2.96139909	2.27E-05	178516	1902	peptidylglycine alpha-amidating monooxygenase	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0018032-&&-protein amidation-%%-GO:0007595-&&-lactation-%%-GO:0009268-&&-response to pH-%%-GO:0007417-&&-central nervous system development-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009404-&&-toxin metabolic process-%%-GO:0001519-&&-peptide amidation-%%-GO:0022602-&&-ovulation cycle process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0032355-&&-response to estradiol-%%-GO:0042476-&&-odontogenesis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0060173-&&-limb development-%%-GO:0046688-&&-response to copper ion-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043204-&&-perikaryon-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0016020-&&-membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0004504-&&-peptidylglycine monooxygenase activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004598-&&-peptidylamidoglycolate lyase activity	G:9606:PAM				PAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAM	0.33767823	0.03846154	13	4	FALSE	PAM	PAM	52	0	13	0	0.67310015	FALSE	0	PAM	17134	0.09014845
787967	taxon:9606	2.84339058	6.81E-06	178489	1902	propionyl-CoA carboxylase beta subunit	gene	biological_process-&-1&-GO:0019626-&&-short-chain fatty acid catabolic process-%%-GO:0006768-&&-biotin metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004658-&&-propionyl-CoA carboxylase activity	G:9606:PCCB			KEGG-&-1&-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	PCCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCCB	0.3516928	0.10909091	13	4	FALSE	PCCB	PCCB	140.6363636	0	12	0	0.69276824	FALSE	1	PCCB	8410	0.11991601
787975	taxon:9606	3.03797069	3.52E-05	178476	1902	procollagen C-endopeptidase enhancer	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010952-&&-positive regulation of peptidase activity|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0016504-&&-peptidase activator activity-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0008201-&&-heparin binding	G:9606:PCOLCE	PCOLCE	TRUE		PCOLCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCOLCE	0.3291671	0.08974359	13	4	FALSE	PCOLCE	PCOLCE	36	0	13	0	0.66033822	FALSE	0	PCOLCE	35924	0.0913215
787981	taxon:9606	3.04190956	3.79E-06	162079	1902	SH3 and cysteine rich domain 3	gene	biological_process-&-1&-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0007274-&&-neuromuscular synaptic transmission|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:STAC3				STAC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAC3	0.32874087	0.03636364	13	5	FALSE	STAC3	STAC3	56.09090909	0	12	0	0.65968174	FALSE	1	STAC3	3952	0.13558569
788029	taxon:9606	2.84906255	1.45E-05	178333	1902	roundabout guidance receptor 2	gene	biological_process-&-1&-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0051964-&&-negative regulation of synapse assembly-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0001656-&&-metanephros development-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0007417-&&-central nervous system development-%%-GO:0021891-&&-olfactory bulb interneuron development-%%-GO:0061364-&&-apoptotic process involved in luteolysis-%%-GO:0001657-&&-ureteric bud development-%%-GO:0007411-&&-axon guidance-%%-GO:0021510-&&-spinal cord development-%%-GO:0007420-&&-brain development-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0050925-&&-negative regulation of negative chemotaxis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030673-&&-axolemma-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0008046-&&-axon guidance receptor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding	G:9606:ROBO2			KEGG-&-1&-hsa04360-&&-Axon guidance	ROBO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROBO2	0.35099265	0.06410256	13	4	FALSE	ROBO2	ROBO2	102.3076923	0	13	0	0.69182291	FALSE	0	ROBO2	14226	0.09028914
788083	taxon:9606	2.70710572	3.80E-06	178270	1902	ribosomal protein L36a	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0002181-&&-cytoplasmic translation-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005840-&&-ribosome|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome-%%-GO:0005515-&&-protein binding	G:9606:RPL36A			KEGG-&-1&-hsa03010-&&-Ribosome	RPL36A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL36A	0.36939821	0.12820513	13	4	FALSE	RPL36A	RPL36A	239	0	13	0	0.71548238	FALSE	0	RPL36A	11546	0.12215574
788121	taxon:9606	2.81912715	6.27E-06	178204	1902	protein tyrosine phosphatase, receptor type E	gene	biological_process-&-1&-GO:0033003-&&-regulation of mast cell activation-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PTPRE				PTPRE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRE	0.35471972	0.29090909	13	5	FALSE	PTPRE	PTPRE	190.2727273	0	12	0	0.69681214	FALSE	1	PTPRE	7858	0.14911656
788123	taxon:9606	2.7928155	1.28E-05	178206	1902	protein tyrosine phosphatase, receptor type D	gene	biological_process-&-1&-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0007185-&&-transmembrane receptor protein tyrosine phosphatase signaling pathway-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0097105-&&-presynaptic membrane assembly-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity-%%-GO:0005102-&&-receptor binding	G:9606:PTPRD				PTPRD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRD	0.3580616	0.14545455	13	5	FALSE	PTPRD	PTPRD	153.3636364	0	12	0	0.70119742	FALSE	1	PTPRD	16722	0.10668356
788124	taxon:9606	2.89585631	6.05E-06	178201	1902	protein tyrosine phosphatase, receptor type H	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0031528-&&-microvillus membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRH				PTPRH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRH	0.345321	0.18181818	13	4	FALSE	PTPRH	PTPRH	111.6363636	0	12	0	0.68402395	FALSE	1	PTPRH	9238	0.12597696
788326	taxon:9606	2.64030251	2.88E-05	177876	1902	SET binding factor 1	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0019208-&&-phosphatase regulator activity	G:9606:SBF1				SBF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SBF1	0.37874448	0.03846154	13	4	FALSE	SBF1	SBF1	265.5384615	0	13	0	0.72661625	FALSE	0	SBF1	39384	0.11168764
788533	taxon:9606	2.86828423	9.54E-06	177490	1902	sialophorin	gene	biological_process-&-1&-GO:0001808-&&-negative regulation of type IV hypersensitivity-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0031295-&&-T cell costimulation-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0050900-&&-leukocyte migration-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0006935-&&-chemotaxis-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0050688-&&-regulation of defense response to virus-%%-GO:0045060-&&-negative thymic T cell selection-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0001562-&&-response to protozoan-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006968-&&-cellular defense response-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0001931-&&-uropod|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:SPN			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	SPN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPN	0.34864048	0.15384615	13	4	FALSE	SPN	SPN	102.6923077	0	13	0	0.6886193	FALSE	0	SPN	11172	0.10207838
788583	taxon:9606	2.87175043	6.45E-06	177399	1902	TAR (HIV-1) RNA binding protein 1	gene	biological_process-&-1&-GO:0000453-&&-enzyme-directed rRNA 2'-O-methylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0030488-&&-tRNA methylation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0016423-&&-tRNA (guanine) methyltransferase activity-%%-GO:0070039-&&-rRNA (guanosine-2'-O-)-methyltransferase activity	G:9606:TARBP1				TARBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARBP1	0.34821967	0.06410256	13	4	FALSE	TARBP1	TARBP1	104.4615385	0	13	0	0.68804159	FALSE	0	TARBP1	8360	0.10434044
788645	taxon:9606	2.85678273	1.40E-05	177257	1902	trefoil factor 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042060-&&-wound healing-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0010039-&&-response to iron ion-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0007586-&&-digestion-%%-GO:0030154-&&-cell differentiation-%%-GO:0030277-&&-maintenance of gastrointestinal epithelium|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding	G:9606:TFF1			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	TFF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFF1	0.35004412	0.05454545	13	5	FALSE	TFF1	TFF1	117.7272727	0	12	0	0.69053621	FALSE	1	TFF1	14438	0.1124379
788664	taxon:9606	2.79832992	1.19E-05	177235	1902	tyrosine hydroxylase	gene	biological_process-&-1&-GO:0051412-&&-response to corticosterone-%%-GO:0006631-&&-fatty acid metabolic process-%%-GO:0006665-&&-sphingolipid metabolic process-%%-GO:0042418-&&-epinephrine biosynthetic process-%%-GO:0033076-&&-isoquinoline alkaloid metabolic process-%%-GO:0009635-&&-response to herbicide-%%-GO:0007612-&&-learning-%%-GO:0046684-&&-response to pyrethroid-%%-GO:0045472-&&-response to ether-%%-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0001975-&&-response to amphetamine-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0007626-&&-locomotory behavior-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007617-&&-mating behavior-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0052314-&&-phytoalexin metabolic process-%%-GO:0015842-&&-aminergic neurotransmitter loading into synaptic vesicle-%%-GO:0035176-&&-social behavior-%%-GO:0007601-&&-visual perception-%%-GO:0007613-&&-memory-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0018963-&&-phthalate metabolic process-%%-GO:0003007-&&-heart morphogenesis-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0009414-&&-response to water deprivation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0042423-&&-catecholamine biosynthetic process-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0001963-&&-synaptic transmission, dopaminergic-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0007507-&&-heart development-%%-GO:0009416-&&-response to light stimulus-%%-GO:0042421-&&-norepinephrine biosynthetic process-%%-GO:0043473-&&-pigmentation-%%-GO:0071287-&&-cellular response to manganese ion-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0071316-&&-cellular response to nicotine-%%-GO:0032355-&&-response to estradiol-%%-GO:0045471-&&-response to ethanol-%%-GO:0042214-&&-terpene metabolic process-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0016137-&&-glycoside metabolic process-%%-GO:0042755-&&-eating behavior-%%-GO:0009651-&&-response to salt stress-%%-GO:0035900-&&-response to isolation stress-%%-GO:0006585-&&-dopamine biosynthetic process from tyrosine-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0014823-&&-response to activity-%%-GO:0042745-&&-circadian sleep/wake cycle-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0010043-&&-response to zinc ion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005790-&&-smooth endoplasmic reticulum-%%-GO:0033162-&&-melanosome membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0043005-&&-neuron projection-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0043195-&&-terminal bouton-%%-GO:0030425-&&-dendrite-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0004511-&&-tyrosine 3-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0005515-&&-protein binding-%%-GO:0034617-&&-tetrahydrobiopterin binding-%%-GO:0016597-&&-amino acid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0035240-&&-dopamine binding-%%-GO:0008199-&&-ferric iron binding	G:9606:TH	TH	TRUE	KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05012-&&-Parkinson disease-%%-hsa01100-&&-Metabolic pathways-%%-hsa05034-&&-Alcoholism-%%-hsa00790-&&-Folate biosynthesis-%%-hsa05030-&&-Cocaine addiction-%%-hsa05031-&&-Amphetamine addiction	TH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TH	0.357356	0.25641026	13	4	FALSE	TH	TH	206.0769231	0	13	0	0.70027835	FALSE	0	TH	12296	0.14583787
788679	taxon:9606	2.85473452	1.31E-05	177211	1902	intercellular adhesion molecule 5	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0050776-&&-regulation of immune response-%%-GO:0006909-&&-phagocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding	G:9606:ICAM5				ICAM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICAM5	0.35029527	0.06410256	13	5	FALSE	ICAM5	ICAM5	105.5384615	0	13	0	0.69087758	FALSE	0	ICAM5	13354	0.09578571
788686	taxon:9606	2.81692138	8.55E-06	177188	1902	TATA element modulatory factor 1	gene	biological_process-&-1&-GO:0033327-&&-Leydig cell differentiation-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0032275-&&-luteinizing hormone secretion-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:2000845-&&-positive regulation of testosterone secretion-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0007289-&&-spermatid nucleus differentiation-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0001675-&&-acrosome assembly-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003712-&&-transcription cofactor activity	G:9606:TMF1				TMF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMF1	0.35499748	0.06410256	13	4	FALSE	TMF1	TMF1	134.5384615	0	13	0	0.69717977	FALSE	0	TMF1	12742	0.10278057
788731	taxon:9606	2.96644084	7.95E-06	177088	1902	transient receptor potential cation channel subfamily C member 3	gene	biological_process-&-1&-GO:0006828-&&-manganese ion transport-%%-GO:0007338-&&-single fertilization-%%-GO:0030168-&&-platelet activation-%%-GO:1903244-&&-positive regulation of cardiac muscle hypertrophy in response to stress-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0007602-&&-phototransduction-%%-GO:0010524-&&-positive regulation of calcium ion transport into cytosol-%%-GO:0051592-&&-response to calcium ion-%%-GO:0006816-&&-calcium ion transport-%%-GO:0033198-&&-response to ATP|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0070679-&&-inositol 1,4,5 trisphosphate binding-%%-GO:0015279-&&-store-operated calcium channel activity-%%-GO:0005515-&&-protein binding	G:9606:TRPC3			KEGG-&-1&-hsa04360-&&-Axon guidance	TRPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPC3	0.33710431	0.14545455	13	5	FALSE	TRPC3	TRPC3	61.45454545	0	12	0	0.67225986	FALSE	1	TRPC3	7382	0.10696122
788805	taxon:9606	2.91681109	4.38E-06	176837	1902	TXK tyrosine kinase	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0010543-&&-regulation of platelet activation-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0001816-&&-cytokine production-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042246-&&-tissue regeneration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060335-&&-positive regulation of interferon-gamma-mediated signaling pathway-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001012-&&-RNA polymerase II regulatory region DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:TXK			KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration	TXK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXK	0.34284017	0.30909091	13	5	FALSE	TXK	TXK	120.4545455	0	12	0	0.68053148	FALSE	1	TXK	7178	0.1475739
788927	taxon:9606	2.90011029	1.80E-05	176583	1902	reversion inducing cysteine rich protein with kazal motifs	gene	biological_process-&-1&-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:1904684-&&-negative regulation of metalloendopeptidase activity-%%-GO:0007566-&&-embryo implantation-%%-GO:0001955-&&-blood vessel maturation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:RECK			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	RECK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RECK	0.34481447	0	13	4	FALSE	RECK	RECK	99.61538462	0	13	0	0.68331495	FALSE	0	RECK	25474	0.11206294
788939	taxon:9606	2.74019222	4.23E-06	176559	1902	Kruppel like factor 11	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0000083-&&-regulation of transcription involved in G1/S transition of mitotic cell cycle-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding	G:9606:KLF11				KLF11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF11	0.3649379	0.14102564	13	4	FALSE	KLF11	KLF11	210.7692308	0	13	0	0.70996796	FALSE	0	KLF11	11252	0.12111293
788961	taxon:9606	2.68363006	5.39E-06	176525	1902	poly(ADP-ribose) glycohydrolase	gene	biological_process-&-1&-GO:0005975-&&-carbohydrate metabolic process-%%-GO:1990966-&&-ATP generation from poly-ADP-D-ribose|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004649-&&-poly(ADP-ribose) glycohydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:PARG				PARG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARG	0.3726296	0.24358974	13	4	FALSE	PARG	PARG	271.9230769	0	13	0	0.71939499	FALSE	0	PARG	12540	0.12828983
789106	taxon:9606	3.03623759	4.68E-06	176187	1902	myotubularin related protein 2	gene	biological_process-&-1&-GO:2000643-&&-positive regulation of early endosome to late endosome transport-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0090394-&&-negative regulation of excitatory postsynaptic potential-%%-GO:0097062-&&-dendritic spine maintenance-%%-GO:2000645-&&-negative regulation of receptor catabolic process-%%-GO:0032288-&&-myelin assembly-%%-GO:0031642-&&-negative regulation of myelination-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0046856-&&-phosphatidylinositol dephosphorylation-%%-GO:0051262-&&-protein tetramerization-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0002091-&&-negative regulation of receptor internalization-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0046855-&&-inositol phosphate dephosphorylation-%%-GO:0048666-&&-neuron development|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0043197-&&-dendritic spine-%%-GO:0005634-&&-nucleus-%%-GO:0097060-&&-synaptic membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005774-&&-vacuolar membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0030425-&&-dendrite-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0052629-&&-phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0004438-&&-phosphatidylinositol-3-phosphatase activity	G:9606:MTMR2			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	MTMR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTMR2	0.32935499	0.14545455	13	5	FALSE	MTMR2	MTMR2	41.27272727	0	12	0	0.66062707	FALSE	1	MTMR2	3620	0.1091884
789141	taxon:9606	2.7876162	1.50E-05	176121	1902	myelin protein zero like 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:MPZL1			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	MPZL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPZL1	0.35872944	0.08974359	13	4	FALSE	MPZL1	MPZL1	148.8461539	0	13	0	0.70206397	FALSE	0	MPZL1	19224	0.10012457
789158	taxon:9606	3.01102883	1.56E-05	176082	1902	claudin 1	gene	biological_process-&-1&-GO:0061772-&&-drug transport across blood-nerve barrier-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0097421-&&-liver regeneration-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0061436-&&-establishment of skin barrier-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0009636-&&-response to toxic substance-%%-GO:0071548-&&-response to dexamethasone-%%-GO:0007568-&&-aging-%%-GO:0008065-&&-establishment of blood-nerve barrier-%%-GO:0045471-&&-response to ethanol-%%-GO:0016338-&&-calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0070673-&&-response to interleukin-18-%%-GO:0071284-&&-cellular response to lead ion-%%-GO:1903348-&&-positive regulation of bicellular tight junction assembly-%%-GO:0051260-&&-protein homooligomerization-%%-GO:1903545-&&-cellular response to butyrate-%%-GO:0042538-&&-hyperosmotic salinity response-%%-GO:0070830-&&-bicellular tight junction assembly|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity	G:9606:CLDN1			KEGG-&-1&-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction	CLDN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLDN1	0.3321124	0.05454545	13	4	FALSE	CLDN1	CLDN1	46.27272727	0	12	0	0.66482853	FALSE	1	CLDN1	12684	0.10609576
789182	taxon:9606	2.75925634	2.23E-06	176042	1902	histone cluster 1 H2B family member n	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BN			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BN	0.36241649	0.19230769	13	4	FALSE	HIST1H2BN	HIST1H2BN	288.6153846	0	13	0	0.70679061	FALSE	0	HIST1H2BN	10752	0.17105684
789246	taxon:9606	2.6681897	5.32E-06	175897	1902	DEAD-box helicase 3, Y-linked	gene	biological_process-&-1&-GO:0006413-&&-translational initiation-%%-GO:0010501-&&-RNA secondary structure unwinding-%%-GO:0010468-&&-regulation of gene expression|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0036464-&&-cytoplasmic ribonucleoprotein granule-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity-%%-GO:0003723-&&-RNA binding	G:9606:DDX3Y				DDX3Y	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX3Y	0.37478595	0.07692308	13	4	FALSE	DDX3Y	DDX3Y	295	0	13	0	0.72196838	FALSE	0	DDX3Y	17132	0.13489715
789362	taxon:9606	2.82858043	1.03E-05	175661	1902	thymosin beta 10	gene	biological_process-&-1&-GO:0007015-&&-actin filament organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0005515-&&-protein binding	G:9606:TMSB10				TMSB10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMSB10	0.35353423	0.14102564	13	5	FALSE	TMSB10	TMSB10	134.6923077	0	13	0	0.69523659	FALSE	0	TMSB10	12184	0.10373321
789375	taxon:9606	2.70395462	8.57E-06	175638	1902	doublecortin like kinase 1	gene	biological_process-&-1&-GO:0001764-&&-neuron migration-%%-GO:0030900-&&-forebrain development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0048675-&&-axon extension-%%-GO:0009615-&&-response to virus-%%-GO:0007399-&&-nervous system development-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016197-&&-endosomal transport-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0021952-&&-central nervous system projection neuron axonogenesis-%%-GO:0007417-&&-central nervous system development-%%-GO:0018107-&&-peptidyl-threonine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0014069-&&-postsynaptic density|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:DCLK1				DCLK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCLK1	0.36982869	0.15384615	13	4	FALSE	DCLK1	DCLK1	199.4615385	0	13	0	0.71600756	FALSE	0	DCLK1	17176	0.10136483
789434	taxon:9606	2.79738459	7.85E-06	175481	1902	copine 6	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0046474-&&-glycerophospholipid biosynthetic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0007399-&&-nervous system development-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0030425-&&-dendrite-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0001786-&&-phosphatidylserine binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:CPNE6				CPNE6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPNE6	0.35747677	0.03846154	13	4	FALSE	CPNE6	CPNE6	165	0	13	0	0.7004359	FALSE	0	CPNE6	14572	0.11900256
789474	taxon:9606	2.94879471	4.78E-06	175381	1902	nuclear factor, erythroid 2 like 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:NFE2L3				NFE2L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFE2L3	0.33912161	0.45454545	13	4	FALSE	NFE2L3	NFE2L3	86.18181818	0	12	0	0.67520088	FALSE	1	NFE2L3	6118	0.11887147
789520	taxon:9606	2.82495667	1.06E-05	175269	1902	ATP binding cassette subfamily B member 6 (Langereis blood group)	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006779-&&-porphyrin-containing compound biosynthetic process-%%-GO:0007420-&&-brain development-%%-GO:0043588-&&-skin development-%%-GO:0006810-&&-transport-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0015886-&&-heme transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005768-&&-endosome-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043190-&&-ATP-binding cassette (ABC) transporter complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005740-&&-mitochondrial envelope-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0015439-&&-heme-transporting ATPase activity-%%-GO:0015562-&&-efflux transmembrane transporter activity-%%-GO:0015232-&&-heme transporter activity-%%-GO:0020037-&&-heme binding	G:9606:ABCB6			KEGG-&-1&-hsa02010-&&-ABC transporters	ABCB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCB6	0.35398773	0.07692308	13	4	FALSE	ABCB6	ABCB6	156.3846154	0	13	0	0.69584055	FALSE	0	ABCB6	20672	0.11746988
789730	taxon:9606	2.75027572	1.71E-06	174811	1902	SH2B adaptor protein 3	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0030154-&&-cell differentiation-%%-GO:0007596-&&-blood coagulation-%%-GO:0035162-&&-embryonic hemopoiesis|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0035591-&&-signaling adaptor activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:SH2B3	SH2B3	TRUE	KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	SH2B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2B3	0.36359991	0.6	13	5	FALSE	SH2B3	SH2B3	245.5454546	0	12	0	0.70828738	FALSE	1	SH2B3	5000	0.1444385
789754	taxon:9606	2.82070269	1.04E-05	174767	1902	Ts translation elongation factor, mitochondrial	gene	biological_process-&-1&-GO:0006414-&&-translational elongation-%%-GO:0032784-&&-regulation of DNA-templated transcription, elongation-%%-GO:0070125-&&-mitochondrial translational elongation-%%-GO:0070129-&&-regulation of mitochondrial translation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding	G:9606:TSFM				TSFM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSFM	0.35452159	0.03846154	13	5	FALSE	TSFM	TSFM	132.4615385	0	13	0	0.69654955	FALSE	0	TSFM	12888	0.10011097
789757	taxon:9606	2.78147156	1.15E-05	174757	1902	prolactin regulatory element binding	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0003400-&&-regulation of COPII vesicle coating-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0032527-&&-protein exit from endoplasmic reticulum-%%-GO:0009306-&&-protein secretion-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070971-&&-endoplasmic reticulum exit site-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0005090-&&-Sar guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity	G:9606:PREB			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	PREB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PREB	0.35952192	0.03846154	13	4	FALSE	PREB	PREB	161.7692308	0	13	0	0.70308807	FALSE	0	PREB	22286	0.10623194
789815	taxon:9606	2.78714353	6.67E-06	174593	1902	AT-rich interaction domain 5A	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding	G:9606:ARID5A				ARID5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARID5A	0.35879028	0.12820513	13	5	FALSE	ARID5A	ARID5A	169.6153846	0	13	0	0.70214274	FALSE	0	ARID5A	13468	0.11330075
789870	taxon:9606	2.84118481	1.48E-05	174474	1902	solute carrier family 27 member 2	gene	biological_process-&-1&-GO:0044539-&&-long-chain fatty acid import-%%-GO:0001561-&&-fatty acid alpha-oxidation-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0042760-&&-very long-chain fatty acid catabolic process-%%-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097089-&&-methyl-branched fatty acid metabolic process-%%-GO:0006635-&&-fatty acid beta-oxidation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005779-&&-integral component of peroxisomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004467-&&-long-chain fatty acid-CoA ligase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005102-&&-receptor binding-%%-GO:0102391-&&-decanoate--CoA ligase activity-%%-GO:0015245-&&-fatty acid transporter activity-%%-GO:0050197-&&-phytanate-CoA ligase activity-%%-GO:0070251-&&-pristanate-CoA ligase activity-%%-GO:0031957-&&-very long-chain fatty acid-CoA ligase activity	G:9606:SLC27A2			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa04931-&&-Insulin resistance-%%-hsa03320-&&-PPAR signaling pathway	SLC27A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC27A2	0.35196584	0.05128205	13	4	FALSE	SLC27A2	SLC27A2	127.6923077	0	13	0	0.69313586	FALSE	0	SLC27A2	15754	0.10889196
789873	taxon:9606	2.9335119	1.61E-05	174466	1902	kallikrein related peptidase 11	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:KLK11				KLK11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK11	0.34088834	0.03846154	13	5	FALSE	KLK11	KLK11	68.23076923	0	13	0	0.67774802	FALSE	0	KLK11	15296	0.09596236
789882	taxon:9606	2.54025524	1.26E-05	174443	1902	LanC like 1	gene	biological_process-&-1&-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0043295-&&-glutathione binding-%%-GO:0017124-&&-SH3 domain binding-%%-GO:0003824-&&-catalytic activity	G:9606:LANCL1				LANCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LANCL1	0.39366123	0.17948718	13	4	FALSE	LANCL1	LANCL1	436.0769231	0	13	0	0.74329079	FALSE	0	LANCL1	24712	0.14662734
789958	taxon:9606	2.64881046	1.26E-05	174245	1902	Kruppel like factor 8	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:KLF8				KLF8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF8	0.37752796	0.20512821	13	4	FALSE	KLF8	KLF8	263.2307692	0	13	0	0.72519826	FALSE	0	KLF8	18854	0.11504812
790006	taxon:9606	2.72758784	5.46E-06	174129	1902	forkhead box J3	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXJ3				FOXJ3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXJ3	0.36662431	0.12820513	13	4	FALSE	FOXJ3	FOXJ3	203.4615385	0	13	0	0.71206869	FALSE	0	FOXJ3	11074	0.10944037
790068	taxon:9606	2.92516149	2.28E-05	173959	1902	follistatin like 1	gene	biological_process-&-1&-GO:0042594-&&-response to starvation-%%-GO:0030509-&&-BMP signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:FSTL1				FSTL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FSTL1	0.34186147	0.15384615	13	5	FALSE	FSTL1	FSTL1	68	0	13	0	0.67913975	FALSE	0	FSTL1	18262	0.09098428
790082	taxon:9606	2.82842288	1.48E-05	173922	1902	interleukin 1 receptor associated kinase 3	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0009615-&&-response to virus-%%-GO:0010933-&&-positive regulation of macrophage tolerance induction-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045824-&&-negative regulation of innate immune response-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0043242-&&-negative regulation of protein complex disassembly-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0043244-&&-regulation of protein complex disassembly-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0032494-&&-response to peptidoglycan-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010936-&&-negative regulation of macrophage cytokine production-%%-GO:0034122-&&-negative regulation of toll-like receptor signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:IRAK3			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway	IRAK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRAK3	0.35355392	0.10909091	13	5	FALSE	IRAK3	IRAK3	138	0	12	0	0.69526285	FALSE	1	IRAK3	11130	0.10874568
790109	taxon:9606	2.69907043	1.12E-05	173861	1902	vacuolar protein sorting 13 homolog A	gene	biological_process-&-1&-GO:0006895-&&-Golgi to endosome transport-%%-GO:0006914-&&-autophagy-%%-GO:0008104-&&-protein localization-%%-GO:0015031-&&-protein transport-%%-GO:0007399-&&-nervous system development-%%-GO:0007626-&&-locomotory behavior-%%-GO:0035176-&&-social behavior|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0031045-&&-dense core granule|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:VPS13A				VPS13A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS13A	0.37049793	0.23076923	13	4	FALSE	VPS13A	VPS13A	242.1538462	0	13	0	0.7168216	FALSE	0	VPS13A	13970	0.12236878
790184	taxon:9606	2.587049	8.71E-06	173697	1902	zinc finger SWIM-type containing 8	gene	molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:ZSWIM8				ZSWIM8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZSWIM8	0.3865408	0.19230769	13	4	FALSE	ZSWIM8	ZSWIM8	371.6153846	0	13	0	0.73549183	FALSE	0	ZSWIM8	23640	0.13739719
790251	taxon:9606	2.6831574	1.33E-05	173518	1902	VPS39, HOPS complex subunit	gene	biological_process-&-1&-GO:1902774-&&-late endosome to lysosome transport-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0006914-&&-autophagy-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0034058-&&-endosomal vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0097576-&&-vacuole fusion|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0030897-&&-HOPS complex-%%-GO:0030123-&&-AP-3 adaptor complex	G:9606:VPS39				VPS39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS39	0.37269524	0.09090909	13	4	FALSE	VPS39	VPS39	253.9090909	0	12	0	0.71947377	FALSE	1	VPS39	18006	0.11980934
790261	taxon:9606	2.63478809	7.34E-06	173486	1902	SMG5, nonsense mediated mRNA decay factor	gene	biological_process-&-1&-GO:0043487-&&-regulation of RNA stability-%%-GO:0090501-&&-RNA phosphodiester bond hydrolysis-%%-GO:0032210-&&-regulation of telomere maintenance via telomerase-%%-GO:0035303-&&-regulation of dephosphorylation-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0032204-&&-regulation of telomere maintenance-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005697-&&-telomerase holoenzyme complex-%%-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0004540-&&-ribonuclease activity-%%-GO:0005515-&&-protein binding-%%-GO:0042162-&&-telomeric DNA binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0070182-&&-DNA polymerase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0051721-&&-protein phosphatase 2A binding	G:9606:SMG5			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	SMG5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMG5	0.37953716	0.20512821	13	4	FALSE	SMG5	SMG5	244.2307692	0	13	0	0.72753532	FALSE	0	SMG5	16322	0.10296407
790273	taxon:9606	2.66724437	1.70E-05	173464	1902	sirtuin 5	gene	biological_process-&-1&-GO:0036049-&&-peptidyl-lysine desuccinylation-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0036047-&&-peptidyl-lysine demalonylation-%%-GO:0006342-&&-chromatin silencing-%%-GO:0006476-&&-protein deacetylation-%%-GO:0010566-&&-regulation of ketone biosynthetic process-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process-%%-GO:0036046-&&-protein demalonylation-%%-GO:0061698-&&-protein deglutarylation-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0006471-&&-protein ADP-ribosylation-%%-GO:0036048-&&-protein desuccinylation-%%-GO:0061699-&&-peptidyl-lysine deglutarylation|cellular_component-&-1&-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0061697-&&-protein-glutaryllysine deglutarylase activity-%%-GO:0070403-&&-NAD+ binding-%%-GO:0036054-&&-protein-malonyllysine demalonylase activity-%%-GO:0036055-&&-protein-succinyllysine desuccinylase activity-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:SIRT5				SIRT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIRT5	0.37491878	0.07692308	13	4	FALSE	SIRT5	SIRT5	217.0769231	0	13	0	0.72212594	FALSE	0	SIRT5	25332	0.09926354
790318	taxon:9606	2.79817236	7.49E-06	173331	1902	ring finger protein 19A, RBR E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008134-&&-transcription factor binding	G:9606:RNF19A				RNF19A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF19A	0.35737613	0.05128205	13	4	FALSE	RNF19A	RNF19A	140.2307692	0	13	0	0.70030461	FALSE	0	RNF19A	9910	0.10133779
790337	taxon:9606	2.69087758	6.74E-06	173288	1902	PNN interacting serine and arginine rich protein	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:PNISR				PNISR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNISR	0.37162597	0.16666667	13	4	FALSE	PNISR	PNISR	227.1538462	0	13	0	0.71818707	FALSE	0	PNISR	14386	0.10962467
790342	taxon:9606	2.65810619	1.18E-05	173273	1902	dehydrogenase/reductase 7B	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0003674-&&-molecular_function	G:9606:DHRS7B				DHRS7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHRS7B	0.37620769	0.1025641	13	4	FALSE	DHRS7B	DHRS7B	236.8461539	0	13	0	0.72364897	FALSE	0	DHRS7B	28850	0.10517495
790376	taxon:9606	2.61146999	4.79E-06	173180	1902	peptidyl arginine deiminase 4	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006325-&&-chromatin organization-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0036413-&&-histone H3-R26 citrullination-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0018101-&&-protein citrullination-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0036414-&&-histone citrullination-%%-GO:0006464-&&-cellular protein modification process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004668-&&-protein-arginine deiminase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0016990-&&-arginine deiminase activity	G:9606:PADI4				PADI4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PADI4	0.38292609	0.21794872	13	4	FALSE	PADI4	PADI4	326	0	13	0	0.73142167	FALSE	0	PADI4	14946	0.12821522
790415	taxon:9606	2.61572396	9.28E-06	173065	1902	stromal cell derived factor 2 like 1	gene	biological_process-&-1&-GO:0035269-&&-protein O-linked mannosylation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0051787-&&-misfolded protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0004169-&&-dolichyl-phosphate-mannose-protein mannosyltransferase activity	G:9606:SDF2L1				SDF2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDF2L1	0.38230334	0.21794872	13	4	FALSE	SDF2L1	SDF2L1	329.3076923	0	13	0	0.73071267	FALSE	0	SDF2L1	22980	0.131377
790457	taxon:9606	2.82306602	2.08E-05	172799	1902	glucuronic acid epimerase	gene	biological_process-&-1&-GO:0015012-&&-heparan sulfate proteoglycan biosynthetic process-%%-GO:0030210-&&-heparin biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016857-&&-racemase and epimerase activity, acting on carbohydrates and derivatives-%%-GO:0047464-&&-heparosan-N-sulfate-glucuronate 5-epimerase activity-%%-GO:0050379-&&-UDP-glucuronate 5'-epimerase activity	G:9606:GLCE			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	GLCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLCE	0.3542248	0.02564103	13	4	FALSE	GLCE	GLCE	119.6923077	0	13	0	0.69615566	FALSE	0	GLCE	22020	0.09312692
790504	taxon:9606	2.76477076	4.54E-06	172660	1902	F-box protein 24	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO24				FBXO24	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO24	0.36169364	0.15384615	13	4	FALSE	FBXO24	FBXO24	187.6153846	0	13	0	0.70587154	FALSE	0	FBXO24	9572	0.11317685
790513	taxon:9606	2.6751221	1.52E-06	172651	1902	F-box protein 4	gene	biological_process-&-1&-GO:0010608-&&-posttranscriptional regulation of gene expression-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0031648-&&-protein destabilization-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0035726-&&-common myeloid progenitor cell proliferation-%%-GO:0071479-&&-cellular response to ionizing radiation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:1902916-&&-positive regulation of protein polyubiquitination-%%-GO:2000001-&&-regulation of DNA damage checkpoint-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:FBXO4			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	FBXO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO4	0.37381471	0.43636364	13	4	FALSE	FBXO4	FBXO4	311.0909091	0	12	0	0.72081298	FALSE	1	FBXO4	4690	0.14263682
790553	taxon:9606	2.80951631	1.47E-05	172255	1902	family with sequence similarity 162 member A	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0051402-&&-neuron apoptotic process-%%-GO:0071456-&&-cellular response to hypoxia|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM162A				FAM162A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM162A	0.35593315	0.07692308	13	4	FALSE	FAM162A	FAM162A	134.3846154	0	13	0	0.69841395	FALSE	0	FAM162A	18022	0.0979686
790561	taxon:9606	2.91082401	8.50E-06	139367	1902	alpha-crystallin A chain	gene		G:9606:LOC102724652			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	LOC102724652	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC102724652	0.34354533	0.38181818	13	4	FALSE	LOC102724652	LOC102724652	91.36363636	0	12	0	0.68152933	FALSE	1	LOC102724652	10470	0.10968024
790583	taxon:9606	2.66204506	2.46E-05	172072	1902	trafficking protein particle complex 3	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030008-&&-TRAPP complex-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:TRAPPC3				TRAPPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAPPC3	0.37565104	0.1025641	13	4	FALSE	TRAPPC3	TRAPPC3	221.1538462	0	13	0	0.72299249	FALSE	0	TRAPPC3	25846	0.09979492
790687	taxon:9606	2.9153931	3.11E-05	171472	1902	protease, serine 50	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004298-&&-threonine-type endopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:PRSS50				PRSS50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRSS50	0.34300692	0.02564103	13	4	FALSE	PRSS50	PRSS50	67.15384615	0	13	0	0.68076782	FALSE	0	PRSS50	25742	0.08851282
790767	taxon:9606	2.9502127	4.33E-06	171284	1902	glycoprotein VI platelet	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0030168-&&-platelet activation-%%-GO:0007167-&&-enzyme linked receptor protein signaling pathway-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0097197-&&-tetraspanin-enriched microdomain|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:GP6			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction-%%-hsa04611-&&-Platelet activation	GP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GP6	0.33895861	0.26923077	13	5	FALSE	GP6	GP6	83.30769231	0	13	0	0.67496455	FALSE	0	GP6	6514	0.13160773
790844	taxon:9606	2.72254608	1.60E-05	170970	1902	casein kinase 1 gamma 1	gene	biological_process-&-1&-GO:0016055-&&-Wnt signaling pathway-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:CSNK1G1			KEGG-&-1&-hsa04340-&&-Hedgehog signaling pathway	CSNK1G1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSNK1G1	0.36730324	0.11538462	13	5	FALSE	CSNK1G1	CSNK1G1	180.1538462	0	13	0	0.71290899	FALSE	0	CSNK1G1	21120	0.0959793
791026	taxon:9606	2.88451237	6.16E-06	170319	1902	formin binding protein 1 like	gene	biological_process-&-1&-GO:0016050-&&-vesicle organization-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0061024-&&-membrane organization-%%-GO:0097320-&&-plasma membrane tubulation-%%-GO:0030050-&&-vesicle transport along actin filament-%%-GO:0006914-&&-autophagy-%%-GO:0060271-&&-cilium assembly-%%-GO:0010324-&&-membrane invagination-%%-GO:0006900-&&-membrane budding-%%-GO:0072583-&&-clathrin-dependent endocytosis|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051020-&&-GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0008289-&&-lipid binding	G:9606:FNBP1L				FNBP1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FNBP1L	0.34667905	0.1025641	13	5	FALSE	FNBP1L	FNBP1L	93.23076923	0	13	0	0.68591461	FALSE	0	FNBP1L	7458	0.09860884
791090	taxon:9606	2.73845911	2.58E-05	170094	1902	YY1 associated protein 1	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:YY1AP1				YY1AP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YY1AP1	0.36516886	0.03846154	13	4	FALSE	YY1AP1	YY1AP1	185	0	13	0	0.71025681	FALSE	0	YY1AP1	25400	0.10415671
791093	taxon:9606	2.68615094	1.26E-05	170072	1902	phosphoglucomutase 2	gene	biological_process-&-1&-GO:0006098-&&-pentose-phosphate shunt-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0019388-&&-galactose catabolic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0046386-&&-deoxyribose phosphate catabolic process-%%-GO:0006006-&&-glucose metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008973-&&-phosphopentomutase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004614-&&-phosphoglucomutase activity	G:9606:PGM2			KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00230-&&-Purine metabolism-%%-hsa00030-&&-Pentose phosphate pathway	PGM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGM2	0.3722799	0.35897436	13	4	FALSE	PGM2	PGM2	226.3076923	0	13	0	0.71897484	FALSE	0	PGM2	19070	0.1063476
791111	taxon:9606	2.804317	5.61E-06	170004	1902	lysosomal protein transmembrane 4 beta	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:LAPTM4B			KEGG-&-1&-hsa04142-&&-Lysosome	LAPTM4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAPTM4B	0.35659307	0.25641026	13	4	FALSE	LAPTM4B	LAPTM4B	140	0	13	0	0.6992805	FALSE	0	LAPTM4B	7382	0.10051945
791141	taxon:9606	2.73751379	3.37E-06	169896	1902	signal transducing adaptor family member 2	gene	biological_process-&-1&-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:STAP2				STAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAP2	0.36529496	0.3974359	13	4	FALSE	STAP2	STAP2	204.5384615	0	13	0	0.71041437	FALSE	0	STAP2	7348	0.11818586
791246	taxon:9606	2.85694029	6.92E-06	169546	1902	methyltransferase like 3	gene	biological_process-&-1&-GO:0031053-&&-primary miRNA processing-%%-GO:0001510-&&-RNA methylation-%%-GO:0010467-&&-gene expression-%%-GO:0007623-&&-circadian rhythm-%%-GO:0061157-&&-mRNA destabilization-%%-GO:1903679-&&-positive regulation of cap-independent translational initiation-%%-GO:0006382-&&-adenosine to inosine editing-%%-GO:0080009-&&-mRNA methylation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:1990744-&&-primary miRNA methylation-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0036396-&&-MIS complex-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016422-&&-mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:1904047-&&-S-adenosyl-L-methionine binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0008173-&&-RNA methyltransferase activity	G:9606:METTL3				METTL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL3	0.35002482	0.03846154	13	4	FALSE	METTL3	METTL3	167.4615385	0	13	0	0.69050995	FALSE	0	METTL3	10358	0.14241608
791305	taxon:9606	2.63699386	2.62E-05	169277	1902	ankyrin repeat and sterile alpha motif domain containing 1B	gene	biological_process-&-1&-GO:1900383-&&-regulation of synaptic plasticity by receptor localization to synapse|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0015030-&&-Cajal body-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046875-&&-ephrin receptor binding	G:9606:ANKS1B				ANKS1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKS1B	0.37921969	0.14102564	13	4	FALSE	ANKS1B	ANKS1B	243.6153846	0	13	0	0.72716769	FALSE	0	ANKS1B	30580	0.10318392
791437	taxon:9606	2.70757838	6.05E-05	168645	1902	WNK lysine deficient protein kinase 4	gene	biological_process-&-1&-GO:0006821-&&-chloride transport-%%-GO:0010766-&&-negative regulation of sodium ion transport-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0008104-&&-protein localization-%%-GO:0072156-&&-distal tubule morphogenesis-%%-GO:0090188-&&-negative regulation of pancreatic juice secretion-%%-GO:0070294-&&-renal sodium ion absorption-%%-GO:0006811-&&-ion transport-%%-GO:0050794-&&-regulation of cellular process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050801-&&-ion homeostasis-%%-GO:0065009-&&-regulation of molecular function|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019869-&&-chloride channel inhibitor activity	G:9606:WNK4				WNK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNK4	0.36933372	0.14102564	13	4	FALSE	WNK4	WNK4	201.4615385	0	13	0	0.7154036	FALSE	0	WNK4	56802	0.1025249
791461	taxon:9606	2.99133449	2.29E-06	168551	1902	FTO, alpha-ketoglutarate dependent dioxygenase	gene	biological_process-&-1&-GO:0010883-&&-regulation of lipid storage-%%-GO:0035552-&&-oxidative single-stranded DNA demethylation-%%-GO:0035553-&&-oxidative single-stranded RNA demethylation-%%-GO:0044065-&&-regulation of respiratory system process-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0040014-&&-regulation of multicellular organism growth-%%-GO:0042245-&&-RNA repair-%%-GO:0080111-&&-DNA demethylation-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006307-&&-DNA dealkylation involved in DNA repair-%%-GO:0070350-&&-regulation of white fat cell proliferation-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0070989-&&-oxidative demethylation|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0035515-&&-oxidative RNA demethylase activity-%%-GO:0008198-&&-ferrous iron binding-%%-GO:1990931-&&-RNA N6-methyladenosine dioxygenase activity-%%-GO:0035516-&&-oxidative DNA demethylase activity-%%-GO:0043734-&&-DNA-N1-methyladenine dioxygenase activity	G:9606:FTO	FTO	TRUE		FTO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FTO	0.33429896	0.37179487	13	5	FALSE	FTO	FTO	66.84615385	0	13	0	0.66811092	FALSE	0	FTO	3218	0.1285503
791492	taxon:9606	2.85252875	8.76E-06	168400	1902	rabenosyn, RAB effector	gene	biological_process-&-1&-GO:1903358-&&-regulation of Golgi organization-%%-GO:0000011-&&-vacuole inheritance-%%-GO:0015031-&&-protein transport-%%-GO:0034058-&&-endosomal vesicle fusion-%%-GO:0007596-&&-blood coagulation-%%-GO:0006897-&&-endocytosis-%%-GO:0016197-&&-endosomal transport-%%-GO:0034498-&&-early endosome to Golgi transport-%%-GO:0090160-&&-Golgi to lysosome transport-%%-GO:0006895-&&-Golgi to endosome transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0010008-&&-endosome membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0010009-&&-cytoplasmic side of endosome membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:RBSN			KEGG-&-1&-hsa04144-&&-Endocytosis	RBSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBSN	0.35056614	0.07692308	13	4	FALSE	RBSN	RBSN	102.9230769	0	13	0	0.69124521	FALSE	0	RBSN	10778	0.09649822
791497	taxon:9606	3.02347566	2.01E-05	168376	1902	torsin family 3 member A	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity	G:9606:TOR3A				TOR3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOR3A	0.33074518	0.14102564	13	4	FALSE	TOR3A	TOR3A	86.61538462	0	13	0	0.66275406	FALSE	0	TOR3A	19972	0.17459822
791500	taxon:9606	2.90657003	8.12E-06	168370	1902	PDZ and LIM domain 2	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PDLIM2				PDLIM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDLIM2	0.34404814	0.03636364	13	5	FALSE	PDLIM2	PDLIM2	97.27272727	0	12	0	0.68223833	FALSE	1	PDLIM2	10442	0.11305088
791578	taxon:9606	2.73373247	4.34E-06	167942	1902	TELO2 interacting protein 2	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome	G:9606:TTI2				TTI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTI2	0.36580024	0.38461538	13	4	FALSE	TTI2	TTI2	197.4615385	0	13	0	0.71104459	FALSE	0	TTI2	9794	0.11166253
791634	taxon:9606	2.95793288	2.42E-05	167718	1902	butyrophilin like 8	gene	biological_process-&-1&-GO:0002250-&&-adaptive immune response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BTNL8				BTNL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTNL8	0.33807393	0	13	5	FALSE	BTNL8	BTNL8	62.07692308	0	13	0	0.67367785	FALSE	0	BTNL8	22332	0.08412799
791758	taxon:9606	2.75957145	7.67E-06	166992	1902	serine/threonine kinase 40	gene	biological_process-&-1&-GO:0060425-&&-lung morphogenesis-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0003016-&&-respiratory system process-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0048286-&&-lung alveolus development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:STK40				STK40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK40	0.36237511	0.20512821	13	5	FALSE	STK40	STK40	160	0	13	0	0.70673809	FALSE	0	STK40	12476	0.09547646
791832	taxon:9606	2.58893966	1.99E-06	166617	1902	kelch like family member 22	gene	biological_process-&-1&-GO:0006513-&&-protein monoubiquitination-%%-GO:0000070-&&-mitotic sister chromatid segregation-%%-GO:0051301-&&-cell division-%%-GO:0007094-&&-mitotic spindle assembly checkpoint|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005827-&&-polar microtubule-%%-GO:0005813-&&-centrosome-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL22				KLHL22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL22	0.38625852	0.47435897	13	4	FALSE	KLHL22	KLHL22	371.9230769	0	13	0	0.73517672	FALSE	0	KLHL22	6742	0.1387255
791868	taxon:9606	2.80715299	5.23E-04	182958	1902	acetylcholinesterase (Cartwright blood group)	gene	biological_process-&-1&-GO:0006581-&&-acetylcholine catabolic process-%%-GO:0001919-&&-regulation of receptor recycling-%%-GO:0009611-&&-response to wounding-%%-GO:0006260-&&-DNA replication-%%-GO:0007416-&&-synapse assembly-%%-GO:0007399-&&-nervous system development-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0031623-&&-receptor internalization-%%-GO:0008283-&&-cell proliferation-%%-GO:0002076-&&-osteoblast development-%%-GO:0007155-&&-cell adhesion-%%-GO:0045212-&&-neurotransmitter receptor biosynthetic process-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0051262-&&-protein tetramerization-%%-GO:0032223-&&-negative regulation of synaptic transmission, cholinergic-%%-GO:0001507-&&-acetylcholine catabolic process in synaptic cleft-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005605-&&-basal lamina-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0045202-&&-synapse-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030054-&&-cell junction-%%-GO:0043083-&&-synaptic cleft|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043621-&&-protein self-association-%%-GO:0003990-&&-acetylcholinesterase activity-%%-GO:0005518-&&-collagen binding-%%-GO:0042166-&&-acetylcholine binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043236-&&-laminin binding-%%-GO:0004104-&&-cholinesterase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0017171-&&-serine hydrolase activity	G:9606:ACHE	ACHE	TRUE	KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04725-&&-Cholinergic synapse	ACHE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACHE	0.35623281	0.03636364	13	4	FALSE	ACHE	ACHE	138.0909091	0	12	0	0.69880784	FALSE	1	ACHE	416866	0.101077
791880	taxon:9606	2.89506854	1.29E-05	166551	1902	hematopoietic SH2 domain containing	gene	biological_process-&-1&-GO:0042110-&&-T cell activation-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0051902-&&-negative regulation of mitochondrial depolarization-%%-GO:0002903-&&-negative regulation of B cell apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:HSH2D				HSH2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSH2D	0.34541497	0.21794872	13	4	FALSE	HSH2D	HSH2D	97.46153846	0	13	0	0.68415524	FALSE	0	HSH2D	11930	0.11192839
791937	taxon:9606	2.98550496	4.10E-06	166456	1902	ALG2, alpha-1,3/1,6-mannosyltransferase	gene	biological_process-&-1&-GO:0006488-&&-dolichol-linked oligosaccharide biosynthetic process-%%-GO:0033577-&&-protein glycosylation in endoplasmic reticulum-%%-GO:0051592-&&-response to calcium ion-%%-GO:0097502-&&-mannosylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0000033-&&-alpha-1,3-mannosyltransferase activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0004378-&&-GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity-%%-GO:0102704-&&-GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:ALG2			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways	ALG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALG2	0.33495171	0.12727273	13	5	FALSE	ALG2	ALG2	56.63636364	0	12	0	0.66908251	FALSE	1	ALG2	4192	0.11232081
791939	taxon:9606	2.75169371	1.31E-05	182837	1902	alpha-1-microglobulin/bikunin precursor	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0007155-&&-cell adhesion-%%-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0007565-&&-female pregnancy-%%-GO:0016032-&&-viral process-%%-GO:0030163-&&-protein catabolic process-%%-GO:0042167-&&-heme catabolic process-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0019862-&&-IgA binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0020037-&&-heme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046904-&&-calcium oxalate binding-%%-GO:0019855-&&-calcium channel inhibitor activity-%%-GO:0036094-&&-small molecule binding	G:9606:AMBP				AMBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMBP	0.36341254	0.21818182	13	4	FALSE	AMBP	AMBP	196.2727273	0	12	0	0.70805105	FALSE	1	AMBP	16708	0.11733362
792010	taxon:9606	2.72601229	1.77E-05	182733	1902	brain derived neurotrophic factor	gene	biological_process-&-1&-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048668-&&-collateral sprouting-%%-GO:0031547-&&-brain-derived neurotrophic factor receptor signaling pathway-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007399-&&-nervous system development-%%-GO:0048672-&&-positive regulation of collateral sprouting-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0007416-&&-synapse assembly-%%-GO:0031550-&&-positive regulation of brain-derived neurotrophic factor receptor signaling pathway-%%-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:1900122-&&-positive regulation of receptor binding-%%-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016607-&&-nuclear speck-%%-GO:0005576-&&-extracellular region-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005169-&&-neurotrophin TRKB receptor binding-%%-GO:0008083-&&-growth factor activity	G:9606:BDNF	BDNF	TRUE	KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa05030-&&-Cocaine addiction	BDNF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BDNF	0.3668362	0.07272727	13	5	FALSE	BDNF	BDNF	195.2727273	0	12	0	0.71233129	FALSE	1	BDNF	19164	0.1057071
792039	taxon:9606	2.95667244	9.45E-06	182699	1902	BCL2 interacting protein 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0051149-&&-positive regulation of muscle cell differentiation-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:BNIP2				BNIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNIP2	0.33821805	0.07272727	13	5	FALSE	BNIP2	BNIP2	59.18181818	0	12	0	0.67388793	FALSE	1	BNIP2	7436	0.10109718
792090	taxon:9606	2.89002678	2.82E-04	182636	1902	atypical chemokine receptor 2	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006935-&&-chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005884-&&-actin filament-%%-GO:0055037-&&-recycling endosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005769-&&-early endosome|molecular_function-&-1&-GO:0004950-&&-chemokine receptor activity-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0019957-&&-C-C chemokine binding	G:9606:ACKR2				ACKR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACKR2	0.34601755	0.05128205	13	5	FALSE	ACKR2	ACKR2	87.92307692	0	13	0	0.68499554	FALSE	0	ACKR2	251494	0.08307107
792093	taxon:9606	2.75689302	7.05E-06	182619	1902	polo like kinase 3	gene	biological_process-&-1&-GO:0006970-&&-response to osmotic stress-%%-GO:0007113-&&-endomitotic cell cycle-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0051302-&&-regulation of cell division-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0090166-&&-Golgi disassembly-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0044819-&&-mitotic G1/S transition checkpoint-%%-GO:1904716-&&-positive regulation of chaperone-mediated autophagy-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0032465-&&-regulation of cytokinesis-%%-GO:0009314-&&-response to radiation-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:2000777-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005795-&&-Golgi stack-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding	G:9606:PLK3			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway	PLK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLK3	0.36272717	0.15384615	13	4	FALSE	PLK3	PLK3	168.4615385	0	13	0	0.7071845	FALSE	0	PLK3	11180	0.10178804
792101	taxon:9606	2.97904522	8.30E-06	166220	1902	LIM homeobox 4	gene	biological_process-&-1&-GO:0001890-&&-placenta development-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0021526-&&-medial motor column neuron differentiation-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:LHX4				LHX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LHX4	0.33567802	0.02564103	13	5	FALSE	LHX4	LHX4	48.15384615	0	13	0	0.67015913	FALSE	0	LHX4	7034	0.08598105
792113	taxon:9606	2.80935875	1.78E-05	182591	1902	collagen type VII alpha 1 chain	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0008544-&&-epidermis development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005590-&&-collagen type VII trimer-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:COL7A1			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	COL7A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL7A1	0.35595312	0.17948718	13	4	FALSE	COL7A1	COL7A1	126.9230769	0	13	0	0.69844021	FALSE	0	COL7A1	19906	0.09669659
792117	taxon:9606	2.82668977	2.10E-06	182578	1902	collagen type XVII alpha 1 chain	gene	biological_process-&-1&-GO:0031581-&&-hemidesmosome assembly-%%-GO:0008544-&&-epidermis development-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007160-&&-cell-matrix adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005604-&&-basement membrane-%%-GO:0005581-&&-collagen trimer-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030056-&&-hemidesmosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COL17A1			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	COL17A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL17A1	0.35377069	0.2	13	5	FALSE	COL17A1	COL17A1	155.6363636	0	12	0	0.6955517	FALSE	1	COL17A1	3636	0.12142502
792138	taxon:9606	2.87836773	4.51E-05	166144	1902	Bcl2 modifying factor	gene	biological_process-&-1&-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0043276-&&-anoikis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0016459-&&-myosin complex-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BMF			KEGG-&-1&-hsa05206-&&-MicroRNAs in cancer	BMF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMF	0.34741913	0.14102564	13	5	FALSE	BMF	BMF	94.84615385	0	13	0	0.68693871	FALSE	0	BMF	54754	0.09901629
792154	taxon:9606	2.84985032	5.08E-05	166130	1902	mitochondrial calcium uniporter	gene	biological_process-&-1&-GO:0035786-&&-protein complex oligomerization-%%-GO:0036444-&&-mitochondrial calcium uptake-%%-GO:0051561-&&-positive regulation of mitochondrial calcium ion concentration-%%-GO:0006851-&&-mitochondrial calcium ion transport-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0032024-&&-positive regulation of insulin secretion|cellular_component-&-1&-GO:0034704-&&-calcium channel complex-%%-GO:1990246-&&-uniplex complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0031305-&&-integral component of mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0015292-&&-uniporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MCU			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence	MCU	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCU	0.35089562	0.11538462	13	4	FALSE	MCU	MCU	119.1538462	0	13	0	0.69169161	FALSE	0	MCU	46740	0.10303152
792172	taxon:9606	2.68284229	4.30E-05	182476	1902	amphiregulin	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0060598-&&-dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0060744-&&-mammary gland branching involved in thelarche-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0032355-&&-response to estradiol-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0014009-&&-glial cell proliferation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051591-&&-response to cAMP-%%-GO:0060750-&&-epithelial cell proliferation involved in mammary gland duct elongation-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005634-&&-nucleus-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005154-&&-epidermal growth factor receptor binding	G:9606:AREG			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05210-&&-Colorectal cancer	AREG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AREG	0.37273902	0.09090909	13	4	FALSE	AREG	AREG	226.1818182	0	12	0	0.71952629	FALSE	1	AREG	47262	0.1080987
792183	taxon:9606	3.10713723	5.26E-06	166081	1902	cAMP responsive element binding protein 3 like 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1990440-&&-positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0070278-&&-extracellular matrix constituent secretion-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0007275-&&-multicellular organism development-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0035497-&&-cAMP response element binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:CREB3L1			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04916-&&-Melanogenesis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05031-&&-Amphetamine addiction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04934-&&-Cushing syndrome-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05016-&&-Huntington disease-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	CREB3L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREB3L1	0.32183966	0.2	13	5	FALSE	CREB3L1	CREB3L1	39	0	12	0	0.64881046	FALSE	1	CREB3L1	4246	0.11707989
792198	taxon:9606	2.8342524	7.55E-06	182447	1902	arrestin 3	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0006897-&&-endocytosis-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0005515-&&-protein binding-%%-GO:0002046-&&-opsin binding	G:9606:ARR3				ARR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARR3	0.35282673	0.29090909	13	4	FALSE	ARR3	ARR3	151.2727273	0	12	0	0.69429127	FALSE	1	ARR3	7720	0.12346688
792206	taxon:9606	2.66582637	8.53E-05	182416	1902	aspartate beta-hydroxylase	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0097202-&&-activation of cysteine-type endopeptidase activity-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0035108-&&-limb morphogenesis-%%-GO:0045862-&&-positive regulation of proteolysis-%%-GO:0007389-&&-pattern specification process-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0060325-&&-face morphogenesis-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0042264-&&-peptidyl-aspartic acid hydroxylation-%%-GO:0006936-&&-muscle contraction-%%-GO:1901879-&&-regulation of protein depolymerization-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0060021-&&-palate development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0032541-&&-cortical endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004597-&&-peptide-aspartate beta-dioxygenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008307-&&-structural constituent of muscle-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0009055-&&-electron carrier activity	G:9606:ASPH				ASPH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASPH	0.3751182	0.1025641	13	4	FALSE	ASPH	ASPH	234.0769231	0	13	0	0.72236227	FALSE	0	ASPH	83156	0.10638223
792281	taxon:9606	2.80857098	1.91E-05	165919	1902	forkhead box P2	gene	biological_process-&-1&-GO:0021757-&&-caudate nucleus development-%%-GO:0021549-&&-cerebellum development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033574-&&-response to testosterone-%%-GO:0098582-&&-innate vocalization behavior-%%-GO:0043010-&&-camera-type eye development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048286-&&-lung alveolus development-%%-GO:0060013-&&-righting reflex-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0040007-&&-growth-%%-GO:0042297-&&-vocal learning-%%-GO:0009791-&&-post-embryonic development-%%-GO:0002053-&&-positive regulation of mesenchymal cell proliferation-%%-GO:0021758-&&-putamen development-%%-GO:0048745-&&-smooth muscle tissue development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:FOXP2				FOXP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXP2	0.35605296	0.09090909	13	4	FALSE	FOXP2	FOXP2	151.9090909	0	12	0	0.6985715	FALSE	1	FOXP2	18052	0.11079338
792344	taxon:9606	3.00535686	7.53E-06	182193	1902	cholinergic receptor muscarinic 2	gene	biological_process-&-1&-GO:0008016-&&-regulation of heart contraction-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007399-&&-nervous system development-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007207-&&-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007197-&&-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0009615-&&-response to virus|cellular_component-&-1&-GO:0032279-&&-asymmetric synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0032280-&&-symmetric synapse-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043679-&&-axon terminus-%%-GO:0045202-&&-synapse-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0016907-&&-G-protein coupled acetylcholine receptor activity	G:9606:CHRM2	CHRM2	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CHRM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHRM2	0.33273919	0.05454545	13	5	FALSE	CHRM2	CHRM2	53.27272727	0	12	0	0.66577386	FALSE	1	CHRM2	7484	0.10984848
792377	taxon:9606	2.68268473	1.57E-05	182130	1902	carboxypeptidase D	gene	biological_process-&-1&-GO:0016485-&&-protein processing-%%-GO:0006518-&&-peptide metabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004181-&&-metallocarboxypeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0004185-&&-serine-type carboxypeptidase activity	G:9606:CPD				CPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPD	0.37276091	0.02564103	13	4	FALSE	CPD	CPD	243.3076923	0	13	0	0.71955254	FALSE	0	CPD	38020	0.11390394
792400	taxon:9606	2.91082401	8.50E-06	182091	1902	crystallin alpha A	gene	biological_process-&-1&-GO:0042026-&&-protein refolding-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032387-&&-negative regulation of intracellular transport-%%-GO:0007601-&&-visual perception-%%-GO:0050896-&&-response to stimulus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0042802-&&-identical protein binding	G:9606:CRYAA			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	CRYAA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRYAA	0.34354533	0.38181818	13	4	FALSE	CRYAA	CRYAA	91.36363636	0	12	0	0.68152933	FALSE	1	CRYAA	10470	0.10968024
792407	taxon:9606	2.92516149	1.21E-05	182068	1902	colony stimulating factor 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:1904141-&&-positive regulation of microglial cell migration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0038145-&&-macrophage colony-stimulating factor signaling pathway-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0010743-&&-regulation of macrophage derived foam cell differentiation-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0010759-&&-positive regulation of macrophage chemotaxis-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0030278-&&-regulation of ossification-%%-GO:0032946-&&-positive regulation of mononuclear cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0060763-&&-mammary duct terminal end bud growth-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0042488-&&-positive regulation of odontogenesis of dentin-containing tooth-%%-GO:0045651-&&-positive regulation of macrophage differentiation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0060611-&&-mammary gland fat development-%%-GO:0030154-&&-cell differentiation-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1902228-&&-positive regulation of macrophage colony-stimulating factor signaling pathway-%%-GO:0042117-&&-monocyte activation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0008283-&&-cell proliferation-%%-GO:0003006-&&-developmental process involved in reproduction-%%-GO:0002158-&&-osteoclast proliferation-%%-GO:0045657-&&-positive regulation of monocyte differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0016020-&&-membrane-%%-GO:1990682-&&-CSF1-CSF1R complex-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005157-&&-macrophage colony-stimulating factor receptor binding-%%-GO:0005125-&&-cytokine activity	G:9606:CSF1	CSF1	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSF1	0.34186147	0.09090909	13	5	FALSE	CSF1	CSF1	103.5454546	0	12	0	0.67913975	FALSE	1	CSF1	15578	0.1248074
792423	taxon:9606	2.82464156	2.32E-05	165661	1902	serum amyloid A like 1	gene	cellular_component-&-1&-GO:0005615-&&-extracellular space	G:9606:SAAL1				SAAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAAL1	0.35402722	0.02564103	13	5	FALSE	SAAL1	SAAL1	124.7692308	0	13	0	0.69589307	FALSE	0	SAAL1	24756	0.09465649
792491	taxon:9606	2.84937766	1.53E-05	181931	1902	complement component 4 binding protein alpha	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0045959-&&-negative regulation of complement activation, classical pathway-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0030449-&&-regulation of complement activation-%%-GO:1903027-&&-regulation of opsonization|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0044216-&&-other organism cell|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:C4BPA			KEGG-&-1&-hsa05133-&&-Pertussis-%%-hsa04610-&&-Complement and coagulation cascades	C4BPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C4BPA	0.35095383	0.01282051	13	4	FALSE	C4BPA	C4BPA	101.6923077	0	13	0	0.69177039	FALSE	0	C4BPA	14616	0.08924438
792580	taxon:9606	2.8938081	4.25E-06	181783	1902	cyclin T2	gene	biological_process-&-1&-GO:0045737-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:1901409-&&-positive regulation of phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051301-&&-cell division-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007049-&&-cell cycle-%%-GO:0019085-&&-early viral transcription-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019086-&&-late viral transcription|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0008024-&&-cyclin/CDK positive transcription elongation factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0001223-&&-transcription coactivator binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0070063-&&-RNA polymerase binding	G:9606:CCNT2			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	CCNT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNT2	0.34556542	0.25641026	13	5	FALSE	CCNT2	CCNT2	99.30769231	0	13	0	0.68436532	FALSE	0	CCNT2	6300	0.10556465
792616	taxon:9606	2.83267686	8.47E-06	165331	1902	Ras homolog enriched in brain like 1	gene	biological_process-&-1&-GO:0031929-&&-TOR signaling-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0012505-&&-endomembrane system-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:RHEBL1				RHEBL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHEBL1	0.35302297	0.25641026	13	4	FALSE	RHEBL1	RHEBL1	132.4615385	0	13	0	0.69455386	FALSE	0	RHEBL1	10498	0.11181133
792660	taxon:9606	2.84386324	2.77E-04	181618	1902	cytochrome P450 family 3 subfamily A member 4	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0036378-&&-calcitriol biosynthetic process from calciol-%%-GO:0009822-&&-alkaloid catabolic process-%%-GO:0002933-&&-lipid hydroxylation-%%-GO:0042737-&&-drug catabolic process-%%-GO:0070989-&&-oxidative demethylation-%%-GO:0017144-&&-drug metabolic process-%%-GO:0006706-&&-steroid catabolic process-%%-GO:0042738-&&-exogenous drug catabolic process-%%-GO:0042359-&&-vitamin D metabolic process-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0006629-&&-lipid metabolic process|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0050591-&&-quinine 3-monooxygenase activity-%%-GO:0070576-&&-vitamin D 24-hydroxylase activity-%%-GO:0101020-&&-estrogen 16-alpha-hydroxylase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0005496-&&-steroid binding-%%-GO:0102320-&&-1,8-cineole 2-exo-monooxygenase activity-%%-GO:0030343-&&-vitamin D3 25-hydroxylase activity-%%-GO:0070330-&&-aromatase activity-%%-GO:0033780-&&-taurochenodeoxycholate 6alpha-hydroxylase activity-%%-GO:0050649-&&-testosterone 6-beta-hydroxylase activity-%%-GO:0008395-&&-steroid hydroxylase activity-%%-GO:0034875-&&-caffeine oxidase activity-%%-GO:0020037-&&-heme binding-%%-GO:0047638-&&-albendazole monooxygenase activity-%%-GO:0019825-&&-oxygen binding	G:9606:CYP3A4	CYP3A4	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa04976-&&-Bile secretion-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00830-&&-Retinol metabolism	CYP3A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP3A4	0.35163435	0.09090909	13	4	FALSE	CYP3A4	CYP3A4	130.8181818	0	12	0	0.69268946	FALSE	1	CYP3A4	250904	0.11606276
792669	taxon:9606	2.82700488	5.99E-06	165205	1902	SLX4 interacting protein	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SLX4IP				SLX4IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLX4IP	0.35373126	0.01282051	13	4	FALSE	SLX4IP	SLX4IP	124.4615385	0	13	0	0.69549919	FALSE	0	SLX4IP	8416	0.09501567
792688	taxon:9606	3.00645974	1.44E-05	181557	1902	aldo-keto reductase family 1 member C2	gene	biological_process-&-1&-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0071799-&&-cellular response to prostaglandin D stimulus-%%-GO:0007586-&&-digestion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0044598-&&-doxorubicin metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0071395-&&-cellular response to jasmonic acid stimulus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006693-&&-prostaglandin metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0047086-&&-ketosteroid monooxygenase activity-%%-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0018636-&&-phenanthrene 9,10-monooxygenase activity-%%-GO:0047115-&&-trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity-%%-GO:0032052-&&-bile acid binding-%%-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0031406-&&-carboxylic acid binding	G:9606:AKR1C2			KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa05204-&&-Chemical carcinogenesis	AKR1C2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1C2	0.33261713	0.18181818	13	5	FALSE	AKR1C2	AKR1C2	59.45454545	0	12	0	0.66559004	FALSE	1	AKR1C2	14676	0.12893642
792718	taxon:9606	2.73262959	2.32E-05	165123	1902	trafficking protein particle complex 5	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030008-&&-TRAPP complex-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:TRAPPC5				TRAPPC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAPPC5	0.36594788	0.08974359	13	4	FALSE	TRAPPC5	TRAPPC5	211.8461539	0	13	0	0.7112284	FALSE	0	TRAPPC5	30864	0.11553166
792730	taxon:9606	2.87852529	1.29E-05	181486	1902	distal-less homeobox 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0021766-&&-hippocampus development-%%-GO:0021882-&&-regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0046533-&&-negative regulation of photoreceptor cell differentiation-%%-GO:0048755-&&-branching morphogenesis of a nerve-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007420-&&-brain development-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0021893-&&-cerebral cortex GABAergic interneuron fate commitment-%%-GO:0045746-&&-negative regulation of Notch signaling pathway-%%-GO:0021544-&&-subpallium development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:1902871-&&-positive regulation of amacrine cell differentiation-%%-GO:0051216-&&-cartilage development-%%-GO:0021772-&&-olfactory bulb development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:DLX2				DLX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLX2	0.34740011	0.14545455	13	4	FALSE	DLX2	DLX2	105.2727273	0	12	0	0.68691245	FALSE	1	DLX2	13794	0.10726901
792772	taxon:9606	2.72002521	1.90E-05	181399	1902	diphthamide biosynthesis 1	gene	biological_process-&-1&-GO:0017183-&&-peptidyl-diphthamide biosynthetic process from peptidyl-histidine-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DPH1				DPH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPH1	0.36764365	0.08974359	13	4	FALSE	DPH1	DPH1	198.7692308	0	13	0	0.71332913	FALSE	0	DPH1	19520	0.10638825
792790	taxon:9606	2.80226879	6.09E-06	164979	1902	LSM11, U7 small nuclear RNA associated	gene	biological_process-&-1&-GO:0006398-&&-mRNA 3'-end processing by stem-loop binding and cleavage-%%-GO:0008334-&&-histone mRNA metabolic process-%%-GO:0006369-&&-termination of RNA polymerase II transcription-%%-GO:1900087-&&-positive regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005683-&&-U7 snRNP-%%-GO:0071204-&&-histone pre-mRNA 3'end processing complex-%%-GO:0016604-&&-nuclear body-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005697-&&-telomerase holoenzyme complex|molecular_function-&-1&-GO:0071209-&&-U7 snRNA binding-%%-GO:0005515-&&-protein binding	G:9606:LSM11				LSM11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LSM11	0.35685371	0.21794872	13	4	FALSE	LSM11	LSM11	162	0	13	0	0.69962187	FALSE	0	LSM11	10784	0.11402843
792810	taxon:9606	2.65857886	4.77E-06	181328	1902	ELK3, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007165-&&-signal transduction-%%-GO:0042060-&&-wound healing-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0032422-&&-purine-rich negative regulatory element binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ELK3				ELK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELK3	0.37614081	0.19230769	13	5	FALSE	ELK3	ELK3	253.7692308	0	13	0	0.72357019	FALSE	0	ELK3	15272	0.11305361
792811	taxon:9606	2.58988499	1.54E-05	164944	1902	IQ motif containing GTPase activating protein 3	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0008361-&&-regulation of cell size-%%-GO:0071310-&&-cellular response to organic substance-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0070371-&&-ERK1 and ERK2 cascade|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0070856-&&-myosin VI light chain binding-%%-GO:0017048-&&-Rho GTPase binding-%%-GO:0005516-&&-calmodulin binding	G:9606:IQGAP3			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	IQGAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQGAP3	0.38611753	0.02564103	13	4	FALSE	IQGAP3	IQGAP3	313.9230769	0	13	0	0.73501917	FALSE	0	IQGAP3	32114	0.11839465
792833	taxon:9606	2.92626438	8.63E-06	181289	1902	EPH receptor A8	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0007155-&&-cell adhesion-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0006929-&&-substrate-dependent cell migration-%%-GO:0007411-&&-axon guidance-%%-GO:0016322-&&-neuron remodeling-%%-GO:0033628-&&-regulation of cell adhesion mediated by integrin-%%-GO:0031175-&&-neuron projection development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005004-&&-GPI-linked ephrin receptor activity	G:9606:EPHA8			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHA8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA8	0.34173262	0.05454545	13	5	FALSE	EPHA8	EPHA8	80	0	12	0	0.67895594	FALSE	1	EPHA8	7492	0.1097699
792877	taxon:9606	2.68678116	6.66E-06	181236	1902	ETS variant 4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0030154-&&-cell differentiation-%%-GO:0060762-&&-regulation of branching involved in mammary gland duct morphogenesis-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0048863-&&-stem cell differentiation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:ETV4			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	ETV4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETV4	0.37219258	0.14102564	13	4	FALSE	ETV4	ETV4	220.6153846	0	13	0	0.71886981	FALSE	0	ETV4	15530	0.10642884
792892	taxon:9606	2.97542146	2.57E-05	181210	1902	coagulation factor III, tissue factor	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0002541-&&-activation of plasma proteins involved in acute inflammatory response-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007596-&&-blood coagulation-%%-GO:0016485-&&-protein processing-%%-GO:0007598-&&-blood coagulation, extrinsic pathway-%%-GO:0002543-&&-activation of blood coagulation via clotting cascade-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0010641-&&-positive regulation of platelet-derived growth factor receptor signaling pathway|cellular_component-&-1&-GO:1905286-&&-serine-type peptidase complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0031233-&&-intrinsic component of external side of plasma membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0002020-&&-protease binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0004896-&&-cytokine receptor activity	G:9606:F3	F3	TRUE	KEGG-&-1&-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04610-&&-Complement and coagulation cascades	F3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F3	0.33608684	0.07272727	13	5	FALSE	F3	F3	53.90909091	0	12	0	0.67076309	FALSE	1	F3	28236	0.10143178
792920	taxon:9606	2.90987868	9.67E-06	164757	1902	lin-54 DREAM MuvB core complex component	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:LIN54			KEGG-&-1&-hsa04218-&&-Cellular senescence	LIN54	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIN54	0.34365694	0.19230769	13	4	FALSE	LIN54	LIN54	89.84615385	0	13	0	0.68168689	FALSE	0	LIN54	10736	0.10282935
792949	taxon:9606	2.80384434	2.23E-05	181098	1902	fibrillin 2	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0043010-&&-camera-type eye development-%%-GO:0035583-&&-sequestering of TGFbeta in extracellular matrix-%%-GO:0090287-&&-regulation of cellular response to growth factor stimulus-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0048048-&&-embryonic eye morphogenesis-%%-GO:0060346-&&-bone trabecula formation|cellular_component-&-1&-GO:0001527-&&-microfibril-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0030023-&&-extracellular matrix constituent conferring elasticity	G:9606:FBN2				FBN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBN2	0.35665318	0.09090909	13	4	FALSE	FBN2	FBN2	166.3636364	0	12	0	0.69935928	FALSE	1	FBN2	21602	0.11840228
793037	taxon:9606	2.86938711	8.97E-06	180852	1902	glutamate metabotropic receptor 1	gene	biological_process-&-1&-GO:0007196-&&-adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0071257-&&-cellular response to electrical stimulus-%%-GO:0007216-&&-G-protein coupled glutamate receptor signaling pathway-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0038042-&&-dimeric G-protein coupled receptor signaling pathway-%%-GO:0000187-&&-activation of MAPK activity|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0038037-&&-G-protein coupled receptor dimeric complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0038038-&&-G-protein coupled receptor homodimeric complex-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0008066-&&-glutamate receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:GRM1			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04720-&&-Long-term potentiation-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04915-&&-Estrogen signaling pathway	GRM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRM1	0.34850648	0.14545455	13	4	FALSE	GRM1	GRM1	114.8181818	0	12	0	0.68843548	FALSE	1	GRM1	10974	0.11709537
793099	taxon:9606	2.98771073	9.19E-06	180732	1902	1,4-alpha-glucan branching enzyme 1	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0005978-&&-glycogen biosynthetic process-%%-GO:0006091-&&-generation of precursor metabolites and energy|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0004553-&&-hydrolase activity, hydrolyzing O-glycosyl compounds-%%-GO:0003844-&&-1,4-alpha-glucan branching enzyme activity-%%-GO:0043169-&&-cation binding-%%-GO:0005515-&&-protein binding	G:9606:GBE1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00500-&&-Starch and sucrose metabolism	GBE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GBE1	0.33470442	0.03846154	13	4	FALSE	GBE1	GBE1	50.61538462	0	13	0	0.66871488	FALSE	0	GBE1	7818	0.08741259
793225	taxon:9606	2.9418623	5.25E-06	180500	1902	heat shock protein 90 alpha family class B member 3, pseudogene	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006950-&&-response to stress-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function-%%-GO:0051082-&&-unfolded protein binding	G:9606:HSP90AB3P				HSP90AB3P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSP90AB3P	0.33992074	0.06410256	13	4	FALSE	HSP90AB3P	HSP90AB3P	75.53846154	0	13	0	0.67635628	FALSE	0	HSP90AB3P	7224	0.1
793299	taxon:9606	2.70537262	6.86E-06	180352	1902	hemoglobin subunit gamma 2	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005833-&&-hemoglobin complex-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0020037-&&-heme binding	G:9606:HBG2	HBG2	TRUE		HBG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBG2	0.36963485	0.36363636	13	4	FALSE	HBG2	HBG2	289.8181818	0	12	0	0.71577123	FALSE	1	HBG2	12932	0.14654895
793323	taxon:9606	2.89806208	1.01E-05	180319	1902	hematopoietically expressed homeobox	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0007492-&&-endoderm development-%%-GO:0061010-&&-gall bladder development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030878-&&-thyroid gland development-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0048853-&&-forebrain morphogenesis-%%-GO:0090009-&&-primitive streak formation-%%-GO:0030154-&&-cell differentiation-%%-GO:0060431-&&-primary lung bud formation-%%-GO:0034504-&&-protein localization to nucleus-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0002573-&&-myeloid leukocyte differentiation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0006406-&&-mRNA export from nucleus-%%-GO:0061017-&&-hepatoblast differentiation-%%-GO:0030948-&&-negative regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045736-&&-negative regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0009611-&&-response to wounding-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0010621-&&-negative regulation of transcription by transcription factor localization-%%-GO:0061011-&&-hepatic duct development-%%-GO:0031016-&&-pancreas development-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0016973-&&-poly(A)+ mRNA export from nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071103-&&-DNA conformation change-%%-GO:0070365-&&-hepatocyte differentiation-%%-GO:0008283-&&-cell proliferation-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0022027-&&-interkinetic nuclear migration-%%-GO:0010944-&&-negative regulation of transcription by competitive promoter binding-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008190-&&-eukaryotic initiation factor 4E binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0017025-&&-TBP-class protein binding-%%-GO:0071837-&&-HMG box domain binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0008301-&&-DNA binding, bending-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0070491-&&-repressing transcription factor binding	G:9606:HHEX	HHEX	TRUE	KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04950-&&-Maturity onset diabetes of the young	HHEX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HHEX	0.34505817	0.16666667	13	5	FALSE	HHEX	HHEX	92.46153846	0	13	0	0.68365632	FALSE	0	HHEX	12994	0.1055272
793326	taxon:9606	2.97825744	5.71E-06	163929	1902	BCL2 interacting protein like	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0040009-&&-regulation of growth rate|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:BNIPL				BNIPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNIPL	0.33576681	0.10909091	13	5	FALSE	BNIPL	BNIPL	71.90909091	0	12	0	0.67029043	FALSE	1	BNIPL	5912	0.12844785
793340	taxon:9606	3.00472664	2.56E-06	180282	1902	HLF, PAR bZIP transcription factor	gene	biological_process-&-1&-GO:0048511-&&-rhythmic process-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:HLF				HLF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLF	0.33280898	0.45454545	13	5	FALSE	HLF	HLF	80.27272727	0	12	0	0.66587889	FALSE	1	HLF	3366	0.13682904
793356	taxon:9606	2.83661572	1.04E-05	180247	1902	hepatocyte nuclear factor 4 gamma	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:HNF4G			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young	HNF4G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HNF4G	0.35253277	0.03846154	13	4	FALSE	HNF4G	HNF4G	121.6153846	0	13	0	0.69389738	FALSE	0	HNF4G	14372	0.1017871
787030	taxon:9606	2.91019379	1.55E-05	180200	1902	homeobox A5	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016477-&&-cell migration-%%-GO:0060764-&&-cell-cell signaling involved in mammary gland development-%%-GO:0045639-&&-positive regulation of myeloid cell differentiation-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030878-&&-thyroid gland development-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0010870-&&-positive regulation of receptor biosynthetic process-%%-GO:0060749-&&-mammary gland alveolus development-%%-GO:0003016-&&-respiratory system process-%%-GO:0033599-&&-regulation of mammary gland epithelial cell proliferation-%%-GO:0048286-&&-lung alveolus development-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0060441-&&-epithelial tube branching involved in lung morphogenesis-%%-GO:0060574-&&-intestinal epithelial cell maturation-%%-GO:0060435-&&-bronchiole development-%%-GO:0060644-&&-mammary gland epithelial cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0060480-&&-lung goblet cell differentiation-%%-GO:0060638-&&-mesenchymal-epithelial cell signaling-%%-GO:0060535-&&-trachea cartilage morphogenesis-%%-GO:0060484-&&-lung-associated mesenchyme development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:HOXA5				HOXA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXA5	0.34361973	0.06060606	12	5	FALSE	HOXA5	HOXA5	90	0	12	0	0.68163437	FALSE	0	HOXA5	14244	0.09977703
787031	taxon:9606	2.75720813	1.91E-06	180197	1902	homeobox A9	gene	biological_process-&-1&-GO:0045638-&&-negative regulation of myeloid cell differentiation-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXA9			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	HOXA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXA9	0.36268571	0.1969697	12	4	FALSE	HOXA9	HOXA9	218.5	0	12	0	0.70713198	FALSE	0	HOXA9	6048	0.13187311
787037	taxon:9606	2.70616039	1.29E-05	180185	1902	homeobox B7	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HOXB7				HOXB7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB7	0.36952725	0.24242424	12	5	FALSE	HOXB7	HOXB7	249.75	0	12	0	0.71563993	FALSE	0	HOXB7	14860	0.13015128
787083	taxon:9606	2.8889239	1.01E-05	180106	1902	immunoglobulin heavy constant alpha 1	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0060267-&&-positive regulation of respiratory burst-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0006955-&&-immune response-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0003094-&&-glomerular filtration-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0050871-&&-positive regulation of B cell activation-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0071748-&&-monomeric IgA immunoglobulin complex-%%-GO:0071752-&&-secretory dimeric IgA immunoglobulin complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0071751-&&-secretory IgA immunoglobulin complex-%%-GO:0072562-&&-blood microparticle-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0034987-&&-immunoglobulin receptor binding-%%-GO:0003823-&&-antigen binding	G:9606:IGHA1				IGHA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGHA1	0.34614965	0	12	5	FALSE	IGHA1	IGHA1	91.5	0	12	0	0.68517935	FALSE	0	IGHA1	9960	0.09617428
787086	taxon:9606	2.94328029	9.53E-06	180098	1902	immunoglobulin heavy constant gamma 2 (G2m marker)	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0006956-&&-complement activation-%%-GO:0045087-&&-innate immune response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006508-&&-proteolysis-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0050871-&&-positive regulation of B cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042571-&&-immunoglobulin complex, circulating-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0003823-&&-antigen binding-%%-GO:0005515-&&-protein binding-%%-GO:0034987-&&-immunoglobulin receptor binding	G:9606:IGHG2				IGHG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGHG2	0.33975697	0.03030303	12	4	FALSE	IGHG2	IGHG2	77	0	12	0	0.67611995	FALSE	0	IGHG2	9924	0.09954308
787097	taxon:9606	3.04931464	2.97E-05	180062	1902	interleukin 1 alpha	gene	biological_process-&-1&-GO:0002248-&&-connective tissue replacement involved in inflammatory response wound healing-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0071639-&&-positive regulation of monocyte chemotactic protein-1 production-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0034605-&&-cellular response to heat-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0001660-&&-fever generation-%%-GO:2000391-&&-positive regulation of neutrophil extravasation-%%-GO:0008283-&&-cell proliferation-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0006954-&&-inflammatory response-%%-GO:0035234-&&-ectopic germ cell programmed cell death-%%-GO:0046688-&&-response to copper ion-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0006955-&&-immune response-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0005149-&&-interleukin-1 receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005507-&&-copper ion binding	G:9606:IL1A	IL1A	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05132-&&-Salmonella infection-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05020-&&-Prion diseases-%%-hsa04218-&&-Cellular senescence-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05133-&&-Pertussis-%%-hsa04217-&&-Necroptosis-%%-hsa05323-&&-Rheumatoid arthritis	IL1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1A	0.32794254	0.04444444	12	5	FALSE	IL1A	IL1A	38	0	11	0	0.65844756	FALSE	1	IL1A	33376	0.11134328
787098	taxon:9606	3.0330865	3.92E-05	180057	1902	interleukin 2	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045822-&&-negative regulation of heart contraction-%%-GO:0046013-&&-regulation of T cell homeostatic proliferation-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0045591-&&-positive regulation of regulatory T cell differentiation-%%-GO:0050672-&&-negative regulation of lymphocyte proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030217-&&-T cell differentiation-%%-GO:0051024-&&-positive regulation of immunoglobulin secretion-%%-GO:0045471-&&-response to ethanol-%%-GO:0030101-&&-natural killer cell activation-%%-GO:0034105-&&-positive regulation of tissue remodeling-%%-GO:0007155-&&-cell adhesion-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0002250-&&-adaptive immune response-%%-GO:0002903-&&-negative regulation of B cell apoptotic process-%%-GO:0000165-&&-MAPK cascade|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0019209-&&-kinase activator activity-%%-GO:0043208-&&-glycosphingolipid binding-%%-GO:0005134-&&-interleukin-2 receptor binding-%%-GO:0031851-&&-kappa-type opioid receptor binding-%%-GO:0005125-&&-cytokine activity	G:9606:IL2	IL2	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04660-&&-T cell receptor signaling pathway	IL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL2	0.32969716	0.11111111	12	5	FALSE	IL2	IL2	44.4	0	11	0	0.66115225	FALSE	1	IL2	55848	0.11402597
787099	taxon:9606	2.89758941	1.03E-05	180056	1902	interleukin 2 receptor subunit alpha	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0050687-&&-negative regulation of defense response to virus-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0046013-&&-regulation of T cell homeostatic proliferation-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0006955-&&-immune response-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0050777-&&-negative regulation of immune response-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0038110-&&-interleukin-2-mediated signaling pathway-%%-GO:0002664-&&-regulation of T cell tolerance induction-%%-GO:0006924-&&-activation-induced cell death of T cells-%%-GO:0008283-&&-cell proliferation-%%-GO:0002437-&&-inflammatory response to antigenic stimulus-%%-GO:0007166-&&-cell surface receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0019976-&&-interleukin-2 binding-%%-GO:0004911-&&-interleukin-2 receptor activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:IL2RA	IL2RA	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04144-&&-Endocytosis-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL2RA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL2RA	0.34511446	0.15555556	12	5	FALSE	IL2RA	IL2RA	106.4	0	11	0	0.6837351	FALSE	1	IL2RA	10418	0.12015855
787222	taxon:9606	2.87694974	2.30E-06	179838	1902	MCF.2 cell line derived transforming sequence	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0016358-&&-dendrite development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:MCF2				MCF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MCF2	0.34759036	0.11111111	12	4	FALSE	MCF2	MCF2	121.6	0	11	0	0.68717504	FALSE	1	MCF2	4266	0.12835979
787272	taxon:9606	2.93745076	9.20E-06	179769	1902	potassium voltage-gated channel subfamily A member 3	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0030424-&&-axon-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0015271-&&-outward rectifier potassium channel activity-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005251-&&-delayed rectifier potassium channel activity	G:9606:KCNA3				KCNA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNA3	0.34043124	0.07575758	12	5	FALSE	KCNA3	KCNA3	68.58333333	0	12	0	0.67709154	FALSE	0	KCNA3	7424	0.10381679
787288	taxon:9606	2.90326138	7.39E-06	163351	1902	cell division cycle 20B	gene	biological_process-&-1&-GO:1904668-&&-positive regulation of ubiquitin protein ligase activity|molecular_function-&-1&-GO:0010997-&&-anaphase-promoting complex binding-%%-GO:0097027-&&-ubiquitin-protein transferase activator activity-%%-GO:0005515-&&-protein binding	G:9606:CDC20B				CDC20B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC20B	0.34444022	0.03030303	12	4	FALSE	CDC20B	CDC20B	103.1666667	0	12	0	0.68278977	FALSE	0	CDC20B	9332	0.11822376
787408	taxon:9606	2.90121317	5.58E-06	179477	1902	neutrophil cytosolic factor 4	gene	biological_process-&-1&-GO:0016192-&&-vesicle-mediated transport-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0006955-&&-immune response-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0043020-&&-NADPH oxidase complex-%%-GO:0005829-&&-cytosol-%%-GO:0032010-&&-phagolysosome-%%-GO:0016020-&&-membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0016176-&&-superoxide-generating NADPH oxidase activator activity-%%-GO:0005515-&&-protein binding	G:9606:NCF4			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation	NCF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCF4	0.34468339	0.33333333	12	5	FALSE	NCF4	NCF4	94	0	12	0	0.68313114	FALSE	0	NCF4	7636	0.11637753
787507	taxon:9606	2.84118481	2.28E-06	179317	1902	MAX network transcriptional repressor	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007569-&&-cell aging-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003713-&&-transcription coactivator activity	G:9606:MNT				MNT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MNT	0.35196584	0.31111111	12	4	FALSE	MNT	MNT	176.5	0	11	0	0.69313586	FALSE	1	MNT	4076	0.13827451
787509	taxon:9606	2.70096108	1.59E-05	179318	1902	myeloid cell nuclear differentiation antigen	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006968-&&-cellular defense response-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:MNDA				MNDA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MNDA	0.37023858	0.13636364	12	4	FALSE	MNDA	MNDA	241.8333333	0	12	0	0.71650649	FALSE	0	MNDA	26008	0.12155925
787632	taxon:9606	2.74728218	3.74E-06	179059	1902	notch 4	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0030879-&&-mammary gland development-%%-GO:0007221-&&-positive regulation of transcription of Notch receptor target-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0030097-&&-hemopoiesis-%%-GO:0009790-&&-embryo development-%%-GO:0001569-&&-branching involved in blood vessel morphogenesis-%%-GO:0001709-&&-cell fate determination-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0045602-&&-negative regulation of endothelial cell differentiation-%%-GO:0001886-&&-endothelial cell morphogenesis-%%-GO:0001763-&&-morphogenesis of a branching structure|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:NOTCH4			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04330-&&-Notch signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05165-&&-Human papillomavirus infection	NOTCH4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOTCH4	0.3639961	0.17777778	12	4	FALSE	NOTCH4	NOTCH4	260.9	0	11	0	0.7087863	FALSE	1	NOTCH4	11488	0.15025937
787639	taxon:9606	2.8871908	2.66E-05	179040	1902	natriuretic peptide B	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007589-&&-body fluid secretion-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0097746-&&-regulation of blood vessel diameter-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0007168-&&-receptor guanylyl cyclase signaling pathway-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0035815-&&-positive regulation of renal sodium excretion|cellular_component-&-1&-GO:0043234-&&-protein complex-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0008613-&&-diuretic hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005179-&&-hormone activity	G:9606:NPPB	NPPB	TRUE	KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04714-&&-Thermogenesis-%%-hsa04022-&&-cGMP-PKG signaling pathway	NPPB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPPB	0.34635744	0.21212121	12	4	FALSE	NPPB	NPPB	121	0	12	0	0.6854682	FALSE	0	NPPB	35438	0.128683
787653	taxon:9606	2.62628013	1.76E-05	179005	1902	discoidin domain receptor tyrosine kinase 2	gene	biological_process-&-1&-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0090091-&&-positive regulation of extracellular matrix disassembly-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007165-&&-signal transduction-%%-GO:0001503-&&-ossification-%%-GO:0031214-&&-biomineral tissue development-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035988-&&-chondrocyte proliferation-%%-GO:0003416-&&-endochondral bone growth-%%-GO:0010763-&&-positive regulation of fibroblast migration-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0007155-&&-cell adhesion-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0010715-&&-regulation of extracellular matrix disassembly|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0038062-&&-protein tyrosine kinase collagen receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005518-&&-collagen binding	G:9606:DDR2	DDR2	TRUE		DDR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDR2	0.38076669	0.22727273	12	4	FALSE	DDR2	DDR2	282.3333333	0	12	0	0.72895331	FALSE	0	DDR2	21296	0.11541871
787790	taxon:9606	2.9087758	1.75E-05	178782	1902	proline and arginine rich end leucine rich repeat protein	gene	biological_process-&-1&-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0001501-&&-skeletal system development-%%-GO:0007409-&&-axonogenesis-%%-GO:0007569-&&-cell aging-%%-GO:0042340-&&-keratan sulfate catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005796-&&-Golgi lumen|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:PRELP				PRELP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRELP	0.34378724	0.09090909	12	5	FALSE	PRELP	PRELP	84.75	0	12	0	0.6818707	FALSE	0	PRELP	13484	0.09561602
787886	taxon:9606	2.79297306	3.22E-06	162275	1902	kinase suppressor of ras 2	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0019722-&&-calcium-mediated signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:KSR2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	KSR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KSR2	0.35804141	0.43939394	12	5	FALSE	KSR2	KSR2	187.0833333	0	12	0	0.70117116	FALSE	0	KSR2	8908	0.1287566
787949	taxon:9606	2.7761147	1.47E-05	178521	1902	serpin family B member 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042730-&&-fibrinolysis-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINB2			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	SERPINB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB2	0.36021566	0.06666667	12	5	FALSE	SERPINB2	SERPINB2	178.3	0	11	0	0.70398088	FALSE	1	SERPINB2	15764	0.11620915
787985	taxon:9606	2.84276036	4.79E-06	178449	1902	phosphodiesterase 6G	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0016056-&&-rhodopsin mediated signaling pathway-%%-GO:0045742-&&-positive regulation of epidermal growth factor receptor signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway-%%-GO:0045745-&&-positive regulation of G-protein coupled receptor protein signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0097381-&&-photoreceptor disc membrane|molecular_function-&-1&-GO:0047555-&&-3',5'-cyclic-GMP phosphodiesterase activity-%%-GO:0030507-&&-spectrin binding-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0030553-&&-cGMP binding	G:9606:PDE6G			KEGG-&-1&-hsa04744-&&-Phototransduction-%%-hsa00230-&&-Purine metabolism	PDE6G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE6G	0.35177077	0.24444444	12	5	FALSE	PDE6G	PDE6G	153	0	11	0	0.69287327	FALSE	1	PDE6G	7148	0.13161068
788009	taxon:9606	3.38931779	2.61E-05	178404	1902	platelet factor 4	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0045653-&&-negative regulation of megakaryocyte differentiation-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0030816-&&-positive regulation of cAMP metabolic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006954-&&-inflammatory response-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045347-&&-negative regulation of MHC class II biosynthetic process-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045918-&&-negative regulation of cytolysis-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0045651-&&-positive regulation of macrophage differentiation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0048248-&&-CXCR3 chemokine receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008201-&&-heparin binding-%%-GO:0008009-&&-chemokine activity	G:9606:PF4			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	PF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PF4	0.29504463	0.11111111	12	5	FALSE	PF4	PF4	17.4	0	11	0	0.60178037	FALSE	1	PF4	16676	0.11793103
788101	taxon:9606	2.90641248	1.18E-05	178237	1902	phosphorylase kinase regulatory subunit alpha 1	gene	biological_process-&-1&-GO:0005977-&&-glycogen metabolic process-%%-GO:0005980-&&-glycogen catabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005964-&&-phosphorylase kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004689-&&-phosphorylase kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:PHKA1			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04020-&&-Calcium signaling pathway	PHKA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHKA1	0.34406679	0.06666667	12	5	FALSE	PHKA1	PHKA1	97.8	0	11	0	0.68226459	FALSE	1	PHKA1	10140	0.11626794
788232	taxon:9606	2.77343627	8.03E-06	178038	1902	SH3 domain binding glutamate rich protein like	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:SH3BGRL				SH3BGRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3BGRL	0.36056354	0.10606061	12	4	FALSE	SH3BGRL	SH3BGRL	169.8333333	0	12	0	0.70442729	FALSE	0	SH3BGRL	12106	0.10900322
788341	taxon:9606	3.08886088	2.55E-05	177840	1902	C-C motif chemokine ligand 3	gene	biological_process-&-1&-GO:0001775-&&-cell activation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0071621-&&-granulocyte chemotaxis-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:2000503-&&-positive regulation of natural killer cell chemotaxis-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0070723-&&-response to cholesterol-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0043308-&&-eosinophil degranulation-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006887-&&-exocytosis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0014808-&&-release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0006816-&&-calcium ion transport-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0007610-&&-behavior-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0006935-&&-chemotaxis-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006954-&&-inflammatory response-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0023052-&&-signaling-%%-GO:0007267-&&-cell-cell signaling|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016004-&&-phospholipase activator activity-%%-GO:0016301-&&-kinase activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0031726-&&-CCR1 chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0031730-&&-CCR5 chemokine receptor binding-%%-GO:0004698-&&-calcium-dependent protein kinase C activity	G:9606:CCL3	CCL3	TRUE	KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CCL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL3	0.32374394	0.24444444	12	5	FALSE	CCL3	CCL3	34	0	11	0	0.65185652	FALSE	1	CCL3	25906	0.12210145
788358	taxon:9606	2.92500394	4.17E-05	177808	1902	C-X-C motif chemokine ligand 12	gene	biological_process-&-1&-GO:0060326-&&-cell chemotaxis-%%-GO:0001764-&&-neuron migration-%%-GO:1903237-&&-negative regulation of leukocyte tethering or rolling-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0033603-&&-positive regulation of dopamine secretion-%%-GO:0009314-&&-response to radiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:2000107-&&-negative regulation of leukocyte apoptotic process-%%-GO:0006952-&&-defense response-%%-GO:0006935-&&-chemotaxis-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0048842-&&-positive regulation of axon extension involved in axon guidance-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0050918-&&-positive chemotaxis-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0007411-&&-axon guidance-%%-GO:0008015-&&-blood circulation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0008064-&&-regulation of actin polymerization or depolymerization-%%-GO:0009615-&&-response to virus-%%-GO:0009408-&&-response to heat-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:1990478-&&-response to ultrasound-%%-GO:0022029-&&-telencephalon cell migration-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0042379-&&-chemokine receptor binding-%%-GO:0045236-&&-CXCR chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0008083-&&-growth factor activity	G:9606:CXCL12			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05323-&&-Rheumatoid arthritis	CXCL12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL12	0.34187988	0.13333333	12	4	FALSE	CXCL12	CXCL12	98.2	0	11	0	0.67916601	FALSE	1	CXCL12	53932	0.11252874
788367	taxon:9606	2.86828423	1.96E-05	177795	1902	selectin L	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0033198-&&-response to ATP-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0002020-&&-protease binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0043208-&&-glycosphingolipid binding	G:9606:SELL	SELL	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	SELL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELL	0.34864048	0.13636364	12	5	FALSE	SELL	SELL	104.5	0	12	0	0.6886193	FALSE	0	SELL	18166	0.10400066
788418	taxon:9606	2.83582795	1.72E-05	177710	1902	semenogelin I	gene	biological_process-&-1&-GO:0019731-&&-antibacterial humoral response-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0090281-&&-negative regulation of calcium ion import-%%-GO:1901318-&&-negative regulation of flagellated sperm motility-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0050817-&&-coagulation-%%-GO:1900005-&&-positive regulation of serine-type endopeptidase activity-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007320-&&-insemination|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043234-&&-protein complex-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:SEMG1				SEMG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEMG1	0.3526307	0.07575758	12	4	FALSE	SEMG1	SEMG1	113.8333333	0	12	0	0.69402867	FALSE	0	SEMG1	16184	0.09580163
788431	taxon:9606	2.89664408	3.66E-05	177682	1902	surfactant protein C	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007585-&&-respiratory gaseous exchange|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0097486-&&-multivesicular body lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0045334-&&-clathrin-coated endocytic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042599-&&-lamellar body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SFTPC				SFTPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFTPC	0.34522709	0.06666667	12	4	FALSE	SFTPC	SFTPC	99.6	0	11	0	0.68389265	FALSE	1	SFTPC	46336	0.11783591
788432	taxon:9606	2.7743816	9.99E-06	161293	1902	RAB, member of RAS oncogene family like 3	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005525-&&-GTP binding	G:9606:RABL3				RABL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABL3	0.36044068	0.10606061	12	4	FALSE	RABL3	RABL3	178.25	0	12	0	0.70426973	FALSE	0	RABL3	19646	0.1117567
788450	taxon:9606	3.02253033	2.07E-05	177648	1902	solute carrier family 4 member 2	gene	biological_process-&-1&-GO:0015701-&&-bicarbonate transport-%%-GO:0006820-&&-anion transport-%%-GO:0007283-&&-spermatogenesis-%%-GO:0015698-&&-inorganic anion transport-%%-GO:0048565-&&-digestive tract development-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0098656-&&-anion transmembrane transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0015301-&&-anion:anion antiporter activity-%%-GO:0005452-&&-inorganic anion exchanger activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0008509-&&-anion transmembrane transporter activity	G:9606:SLC4A2			KEGG-&-1&-hsa04971-&&-Gastric acid secretion-%%-hsa04976-&&-Bile secretion-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion	SLC4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC4A2	0.33084862	0.01515152	12	5	FALSE	SLC4A2	SLC4A2	44.58333333	0	12	0	0.66291161	FALSE	0	SLC4A2	12946	0.09368308
788466	taxon:9606	3.00677485	1.88E-05	177587	1902	secretory leukocyte peptidase inhibitor	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0006955-&&-immune response-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0045087-&&-innate immune response-%%-GO:0045071-&&-negative regulation of viral genome replication|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding	G:9606:SLPI	SLPI	TRUE		SLPI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLPI	0.33258227	0.04545455	12	5	FALSE	SLPI	SLPI	44.08333333	0	12	0	0.66553752	FALSE	0	SLPI	15006	0.0935704
788544	taxon:9606	2.70946904	1.52E-05	144693	1902	PHOSPHO2-KLHL23 readthrough	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:PHOSPHO2-KLHL23				PHOSPHO2-KLHL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHOSPHO2-KLHL23	0.369076	0.12121212	12	4	FALSE	PHOSPHO2-KLHL23	PHOSPHO2-KLHL23	258.0833333	0	12	0	0.71508849	FALSE	0	PHOSPHO2-KLHL23	21800	0.13240836
788589	taxon:9606	2.86891445	6.10E-06	177391	1902	tubulin folding cofactor A	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0007021-&&-tubulin complex assembly-%%-GO:0007023-&&-post-chaperonin tubulin folding pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding	G:9606:TBCA				TBCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBCA	0.3485639	0	12	4	FALSE	TBCA	TBCA	104	0	12	0	0.68851426	FALSE	0	TBCA	9370	0.1031031
788617	taxon:9606	2.85662518	3.19E-06	177299	1902	TEA domain transcription factor 3	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0048568-&&-embryonic organ development-%%-GO:0055059-&&-asymmetric neuroblast division-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007565-&&-female pregnancy-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0035329-&&-hippo signaling|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding	G:9606:TEAD3			KEGG-&-1&-hsa04392-&&-Hippo signaling pathway - multiple species-%%-hsa04390-&&-Hippo signaling pathway	TEAD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEAD3	0.35006343	0.07575758	12	4	FALSE	TEAD3	TEAD3	119.5	0	12	0	0.69056247	FALSE	0	TEAD3	5422	0.10939896
788624	taxon:9606	2.84953521	1.24E-05	177288	1902	testis-specific kinase 1	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:TESK1				TESK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TESK1	0.35093442	0.13333333	12	4	FALSE	TESK1	TESK1	141.5	0	11	0	0.69174413	FALSE	1	TESK1	9762	0.12246314
788672	taxon:9606	2.83850638	6.15E-06	177222	1902	tyrosine kinase with immunoglobulin like and EGF like domains 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0045026-&&-plasma membrane fusion-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0007498-&&-mesoderm development-%%-GO:0001525-&&-angiogenesis-%%-GO:0032526-&&-response to retinoic acid|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:TIE1				TIE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIE1	0.35229796	0.15555556	12	5	FALSE	TIE1	TIE1	163.5	0	11	0	0.69358227	FALSE	1	TIE1	9980	0.13574397
788675	taxon:9606	3.17661888	3.46E-05	177219	1902	TIMP metallopeptidase inhibitor 3	gene	biological_process-&-1&-GO:0071310-&&-cellular response to organic substance-%%-GO:1904684-&&-negative regulation of metalloendopeptidase activity-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:0002576-&&-platelet degranulation-%%-GO:0010033-&&-response to organic substance-%%-GO:0007601-&&-visual perception-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:1903984-&&-positive regulation of TRAIL-activated apoptotic signaling pathway|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0002020-&&-protease binding	G:9606:TIMP3	TIMP3	TRUE	KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa05206-&&-MicroRNAs in cancer	TIMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMP3	0.31480012	0.04545455	12	5	FALSE	TIMP3	TIMP3	25.33333333	0	12	0	0.63723019	FALSE	0	TIMP3	17940	0.09755291
788769	taxon:9606	2.73357492	7.42E-06	176946	1902	mitogen-activated protein kinase kinase kinase 12	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0007254-&&-JNK cascade-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0000186-&&-activation of MAPKK activity-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016572-&&-histone phosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:2000672-&&-negative regulation of motor neuron apoptotic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K12			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP3K12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K12	0.36582133	0.24242424	12	5	FALSE	MAP3K12	MAP3K12	190.6666667	0	12	0	0.71107085	FALSE	0	MAP3K12	12424	0.10537724
788780	taxon:9606	2.90436427	1.31E-05	176913	1902	frizzled class receptor 5	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0031077-&&-post-embryonic camera-type eye development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0000578-&&-embryonic axis specification-%%-GO:2000810-&&-regulation of bicellular tight junction assembly-%%-GO:0007416-&&-synapse assembly-%%-GO:0008595-&&-anterior/posterior axis specification, embryo-%%-GO:1901382-&&-regulation of chorionic trophoblast cell proliferation-%%-GO:0060718-&&-chorionic trophoblast cell differentiation-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0044332-&&-Wnt signaling pathway involved in dorsal/ventral axis specification-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0048596-&&-embryonic camera-type eye morphogenesis-%%-GO:0002726-&&-positive regulation of T cell cytokine production-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060561-&&-apoptotic process involved in morphogenesis-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0048469-&&-cell maturation-%%-GO:0060061-&&-Spemann organizer formation-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0071219-&&-cellular response to molecule of bacterial origin-%%-GO:1903146-&&-regulation of mitophagy-%%-GO:0001525-&&-angiogenesis-%%-GO:0033077-&&-T cell differentiation in thymus-%%-GO:0060715-&&-syncytiotrophoblast cell differentiation involved in labyrinthine layer development-%%-GO:0060828-&&-regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0031901-&&-early endosome membrane|molecular_function-&-1&-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0017147-&&-Wnt-protein binding	G:9606:FZD5			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	FZD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FZD5	0.34430943	0.15151515	12	4	FALSE	FZD5	FZD5	88.75	0	12	0	0.68260596	FALSE	0	FZD5	10778	0.09820769
788846	taxon:9606	2.77501182	1.58E-05	176762	1902	uroporphyrinogen decarboxylase	gene	biological_process-&-1&-GO:0006783-&&-heme biosynthetic process-%%-GO:0006782-&&-protoporphyrinogen IX biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004853-&&-uroporphyrinogen decarboxylase activity-%%-GO:0005515-&&-protein binding	G:9606:UROD			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism	UROD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UROD	0.36035883	0.06666667	12	4	FALSE	UROD	UROD	184.2	0	11	0	0.7041647	FALSE	1	UROD	16102	0.11859264
788892	taxon:9606	2.72175831	5.42E-06	160282	1902	interferon regulatory factor 2 binding protein 2	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:IRF2BP2				IRF2BP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IRF2BP2	0.36740955	0.07575758	12	4	FALSE	IRF2BP2	IRF2BP2	200.75	0	12	0	0.71304028	FALSE	0	IRF2BP2	12422	0.10612083
788963	taxon:9606	2.69182291	1.48E-06	176523	1902	ectodermal-neural cortex 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0007399-&&-nervous system development-%%-GO:0007275-&&-multicellular organism development-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0010499-&&-proteasomal ubiquitin-independent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:ENC1				ENC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENC1	0.37149546	0.31111111	12	4	FALSE	ENC1	ENC1	285.1	0	11	0	0.71802952	FALSE	1	ENC1	5430	0.13909224
788984	taxon:9606	2.59130298	5.59E-06	176457	1902	SHOC2, leucine rich repeat scaffold protein	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0000164-&&-protein phosphatase type 1 complex|molecular_function-&-1&-GO:0008157-&&-protein phosphatase 1 binding-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0019903-&&-protein phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:SHOC2			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	SHOC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHOC2	0.38590624	0.36363636	12	4	FALSE	SHOC2	SHOC2	338.8333333	0	12	0	0.73478284	FALSE	0	SHOC2	13096	0.12733308
789009	taxon:9606	2.74192532	4.83E-06	176399	1902	solute carrier family 7 member 5	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:1902475-&&-L-alpha-amino acid transmembrane transport-%%-GO:0007399-&&-nervous system development-%%-GO:0015804-&&-neutral amino acid transport-%%-GO:0006810-&&-transport-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0006569-&&-tryptophan catabolic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0006865-&&-amino acid transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0015297-&&-antiporter activity-%%-GO:0015175-&&-neutral amino acid transmembrane transporter activity-%%-GO:0042605-&&-peptide antigen binding-%%-GO:0015179-&&-L-amino acid transmembrane transporter activity-%%-GO:0015171-&&-amino acid transmembrane transporter activity	G:9606:SLC7A5			KEGG-&-1&-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa04150-&&-mTOR signaling pathway	SLC7A5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC7A5	0.36470723	0.12121212	12	4	FALSE	SLC7A5	SLC7A5	205.25	0	12	0	0.70967911	FALSE	0	SLC7A5	15766	0.11654349
789017	taxon:9606	2.77595715	9.98E-06	176375	1902	caseinolytic mitochondrial matrix peptidase proteolytic subunit	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0009368-&&-endopeptidase Clp complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CLPP				CLPP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLPP	0.36023611	0.06666667	12	5	FALSE	CLPP	CLPP	182.9	0	11	0	0.70400714	FALSE	1	CLPP	12758	0.11791721
789070	taxon:9606	2.98802584	5.55E-06	176244	1902	synaptic Ras GTPase activating protein 1	gene	biological_process-&-1&-GO:0008542-&&-visual learning-%%-GO:0016358-&&-dendrite development-%%-GO:0048169-&&-regulation of long-term neuronal synaptic plasticity-%%-GO:0050803-&&-regulation of synapse structure or activity-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0046580-&&-negative regulation of Ras protein signal transduction-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007389-&&-pattern specification process-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043113-&&-receptor clustering-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0050771-&&-negative regulation of axonogenesis|cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031235-&&-intrinsic component of the cytoplasmic side of the plasma membrane|molecular_function-&-1&-GO:0017124-&&-SH3 domain binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:SYNGAP1			KEGG-&-1&-hsa04014-&&-Ras signaling pathway	SYNGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SYNGAP1	0.33466913	0.21212121	12	5	FALSE	SYNGAP1	SYNGAP1	55.58333333	0	12	0	0.66866236	FALSE	0	SYNGAP1	5160	0.11039177
789322	taxon:9606	2.62549236	1.75E-06	175736	1902	RNA guanylyltransferase and 5'-phosphatase	gene	biological_process-&-1&-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0006396-&&-RNA processing-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0098507-&&-polynucleotide 5' dephosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008192-&&-RNA guanylyltransferase activity-%%-GO:0004484-&&-mRNA guanylyltransferase activity-%%-GO:0004651-&&-polynucleotide 5'-phosphatase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0050355-&&-triphosphatase activity	G:9606:RNGTT			KEGG-&-1&-hsa03015-&&-mRNA surveillance pathway	RNGTT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNGTT	0.38088094	0.15555556	12	4	FALSE	RNGTT	RNGTT	378.2	0	11	0	0.72908461	FALSE	1	RNGTT	8650	0.15266559
789350	taxon:9606	2.69623444	6.11E-06	175687	1902	cyclin E2	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:1903827-&&-regulation of cellular protein localization-%%-GO:0000723-&&-telomere maintenance-%%-GO:0051301-&&-cell division-%%-GO:0000075-&&-cell cycle checkpoint-%%-GO:0007129-&&-synapsis-%%-GO:0000079-&&-regulation of cyclin-dependent protein serine/threonine kinase activity-%%-GO:0006270-&&-DNA replication initiation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0097135-&&-cyclin E2-CDK2 complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0016538-&&-cyclin-dependent protein serine/threonine kinase regulator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CCNE2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05215-&&-Prostate cancer-%%-hsa04110-&&-Cell cycle-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05161-&&-Hepatitis B-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04115-&&-p53 signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04218-&&-Cellular senescence-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer	CCNE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNE2	0.37088763	0.3030303	12	5	FALSE	CCNE2	CCNE2	235.75	0	12	0	0.71729426	FALSE	0	CCNE2	10610	0.11417959
789385	taxon:9606	2.60910666	1.16E-05	175609	1902	transforming growth factor beta regulator 4	gene	biological_process-&-1&-GO:0045333-&&-cellular respiration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity	G:9606:TBRG4				TBRG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBRG4	0.38327295	0.09090909	12	4	FALSE	TBRG4	TBRG4	332.4166667	0	12	0	0.73181556	FALSE	0	TBRG4	33956	0.13041487
789406	taxon:9606	2.80841342	5.09E-06	175547	1902	thyroid hormone receptor interactor 11	gene	biological_process-&-1&-GO:0000042-&&-protein targeting to Golgi-%%-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0006486-&&-protein glycosylation-%%-GO:0007030-&&-Golgi organization-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0060122-&&-inner ear receptor stereocilium organization-%%-GO:0003413-&&-chondrocyte differentiation involved in endochondral bone morphogenesis-%%-GO:0003281-&&-ventricular septum development|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0002081-&&-outer acrosomal membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0016607-&&-nuclear speck-%%-GO:0002079-&&-inner acrosomal membrane-%%-GO:0005929-&&-cilium-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus-%%-GO:0030133-&&-transport vesicle-%%-GO:0005801-&&-cis-Golgi network|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:TRIP11				TRIP11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIP11	0.35607293	0.09090909	12	4	FALSE	TRIP11	TRIP11	146.5	0	12	0	0.69859776	FALSE	0	TRIP11	10010	0.10599468
789573	taxon:9606	2.89333543	1.12E-05	175154	1902	membrane associated guanylate kinase, WW and PDZ domain containing 2	gene	biological_process-&-1&-GO:0003402-&&-planar cell polarity pathway involved in axis elongation-%%-GO:0043113-&&-receptor clustering-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0032926-&&-negative regulation of activin receptor signaling pathway-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0038180-&&-nerve growth factor signaling pathway-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0097118-&&-neuroligin clustering involved in postsynaptic membrane assembly-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:2000809-&&-positive regulation of synaptic vesicle clustering|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045202-&&-synapse-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0030425-&&-dendrite-%%-GO:0036057-&&-slit diaphragm-%%-GO:0005770-&&-late endosome|molecular_function-&-1&-GO:0070699-&&-type II activin receptor binding-%%-GO:0046332-&&-SMAD binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0031697-&&-beta-1 adrenergic receptor binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity	G:9606:MAGI2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway	MAGI2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGI2	0.34562187	0.06666667	12	5	FALSE	MAGI2	MAGI2	112.1	0	11	0	0.68444409	FALSE	1	MAGI2	12194	0.12638732
789575	taxon:9606	2.78651331	7.11E-06	175148	1902	apoptosis resistant E3 ubiquitin protein ligase 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:AREL1				AREL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AREL1	0.35887142	0.17777778	12	4	FALSE	AREL1	AREL1	217.6	0	11	0	0.70224778	FALSE	1	AREL1	10554	0.14649596
789587	taxon:9606	2.82007248	9.85E-06	175120	1902	mannose receptor C type 2	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0006897-&&-endocytosis-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:MRC2			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis	MRC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRC2	0.35460082	0.04545455	12	4	FALSE	MRC2	MRC2	132.5	0	12	0	0.69665459	FALSE	0	MRC2	14512	0.10538236
789615	taxon:9606	2.89569876	6.35E-06	175055	1902	copper chaperone for superoxide dismutase	gene	biological_process-&-1&-GO:0051353-&&-positive regulation of oxidoreductase activity-%%-GO:0015680-&&-intracellular copper ion transport-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0006801-&&-superoxide metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004784-&&-superoxide dismutase activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005507-&&-copper ion binding	G:9606:CCS			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	CCS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCS	0.34533979	0.2	12	4	FALSE	CCS	CCS	117.9	0	11	0	0.68405021	FALSE	1	CCS	9504	0.12497343
789753	taxon:9606	2.92153773	9.02E-06	174764	1902	CTD small phosphatase 2	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008420-&&-CTD phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:CTDSP2				CTDSP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTDSP2	0.3422855	0.03030303	12	5	FALSE	CTDSP2	CTDSP2	82.58333333	0	12	0	0.67974371	FALSE	0	CTDSP2	8932	0.10214048
789825	taxon:9606	2.71923744	2.38E-05	174553	1902	patatin like phospholipase domain containing 6	gene	biological_process-&-1&-GO:0046470-&&-phosphatidylcholine metabolic process-%%-GO:0032502-&&-developmental process-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0001525-&&-angiogenesis-%%-GO:0046475-&&-glycerophospholipid catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004622-&&-lysophospholipase activity	G:9606:PNPLA6	PNPLA6	TRUE	KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism	PNPLA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNPLA6	0.36775016	0.04545455	12	4	FALSE	PNPLA6	PNPLA6	202.4166667	0	12	0	0.71346043	FALSE	0	PNPLA6	30434	0.10652059
789877	taxon:9606	2.77312116	3.01E-05	174459	1902	branched chain ketoacid dehydrogenase kinase	gene	biological_process-&-1&-GO:0016310-&&-phosphorylation-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0009063-&&-cellular amino acid catabolic process|cellular_component-&-1&-GO:0005947-&&-mitochondrial alpha-ketoglutarate dehydrogenase complex-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0016301-&&-kinase activity-%%-GO:0047323-&&-[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:BCKDK				BCKDK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCKDK	0.36060451	0	12	5	FALSE	BCKDK	BCKDK	144.6666667	0	12	0	0.70447981	FALSE	0	BCKDK	26620	0.09256873
789883	taxon:9606	2.96754372	1.25E-05	174439	1902	laminin subunit gamma 3	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0000904-&&-cell morphogenesis involved in differentiation-%%-GO:0014002-&&-astrocyte development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005604-&&-basement membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:LAMC3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer	LAMC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMC3	0.33697903	0	12	5	FALSE	LAMC3	LAMC3	56.25	0	12	0	0.67207605	FALSE	0	LAMC3	9216	0.09117162
789886	taxon:9606	2.95336379	4.99E-06	174429	1902	thioredoxin reductase 2	gene	biological_process-&-1&-GO:0045454-&&-cell redox homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0000305-&&-response to oxygen radical|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004791-&&-thioredoxin-disulfide reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:TXNRD2			KEGG-&-1&-hsa05200-&&-Pathways in cancer-%%-hsa00450-&&-Selenocompound metabolism-%%-hsa05225-&&-Hepatocellular carcinoma	TXNRD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TXNRD2	0.33859696	0.07575758	12	5	FALSE	TXNRD2	TXNRD2	79.5	0	12	0	0.67443937	FALSE	0	TXNRD2	5812	0.10730439
789947	taxon:9606	2.96628328	2.29E-06	157894	1902	aldo-keto reductase family 1 member B15	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006703-&&-estrogen biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004303-&&-estradiol 17-beta-dehydrogenase activity	G:9606:AKR1B15				AKR1B15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1B15	0.33712222	0.65151515	12	4	FALSE	AKR1B15	AKR1B15	96	0	12	0	0.67228612	FALSE	0	AKR1B15	2202	0.15660685
789954	taxon:9606	2.78178667	6.28E-06	174252	1902	NADPH oxidase activator 1	gene	biological_process-&-1&-GO:0006801-&&-superoxide metabolic process-%%-GO:0060263-&&-regulation of respiratory burst-%%-GO:0010310-&&-regulation of hydrogen peroxide metabolic process-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0043020-&&-NADPH oxidase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016176-&&-superoxide-generating NADPH oxidase activator activity-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:NOXA1				NOXA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOXA1	0.3594812	0.16666667	12	4	FALSE	NOXA1	NOXA1	179.6666667	0	12	0	0.70303555	FALSE	0	NOXA1	12266	0.12035794
789975	taxon:9606	3.03009296	1.72E-05	174204	1902	nidogen 2	gene	biological_process-&-1&-GO:0071711-&&-basement membrane organization-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0007160-&&-cell-matrix adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005604-&&-basement membrane|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NID2				NID2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NID2	0.33002288	0.04545455	12	5	FALSE	NID2	NID2	43.75	0	12	0	0.66165117	FALSE	0	NID2	11954	0.09900612
789979	taxon:9606	2.72601229	1.11E-05	174203	1902	component of oligomeric golgi complex 2	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0007030-&&-Golgi organization-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000139-&&-Golgi membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0005795-&&-Golgi stack-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0008565-&&-protein transporter activity	G:9606:COG2	COG2	TRUE		COG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG2	0.3668362	0.33333333	12	4	FALSE	COG2	COG2	183.75	0	12	0	0.71233129	FALSE	0	COG2	12016	0.09892183
789982	taxon:9606	2.8624547	9.44E-06	157806	1902	BH3-like motif containing, cell death inducer	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion	G:9606:BLID				BLID	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLID	0.34935051	0.13636364	12	4	FALSE	BLID	BLID	117.9166667	0	12	0	0.68959088	FALSE	0	BLID	13832	0.11349743
789988	taxon:9606	2.61367575	1.00E-05	174183	1902	pleckstrin homology like domain family A member 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0045210-&&-FasL biosynthetic process-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PHLDA1				PHLDA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHLDA1	0.38260293	0.18181818	12	4	FALSE	PHLDA1	PHLDA1	286	0	12	0	0.73105404	FALSE	0	PHLDA1	21230	0.11389
789995	taxon:9606	2.56672444	7.31E-06	174162	1902	AP2 associated kinase 1	gene	biological_process-&-1&-GO:2000369-&&-regulation of clathrin-dependent endocytosis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0061024-&&-membrane organization-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0050821-&&-protein stabilization-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0005905-&&-clathrin-coated pit-%%-GO:0005737-&&-cytoplasm-%%-GO:0019897-&&-extrinsic component of plasma membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0031252-&&-cell leading edge-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005112-&&-Notch binding-%%-GO:0035612-&&-AP-2 adaptor complex binding-%%-GO:0005515-&&-protein binding	G:9606:AAK1				AAK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AAK1	0.38960162	0.46969697	12	4	FALSE	AAK1	AAK1	346.6666667	0	12	0	0.73887926	FALSE	0	AAK1	15942	0.12341284
790198	taxon:9606	2.76918229	1.03E-05	173667	1902	tubulin tyrosine ligase like 5	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0018095-&&-protein polyglutamylation-%%-GO:0007288-&&-sperm axoneme assembly-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060041-&&-retina development in camera-type eye|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005929-&&-cilium-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016874-&&-ligase activity	G:9606:TTLL5				TTLL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTLL5	0.36111743	0.31818182	12	4	FALSE	TTLL5	TTLL5	191.5833333	0	12	0	0.70513628	FALSE	0	TTLL5	16092	0.11608045
790201	taxon:9606	2.67622499	3.04E-06	173652	1902	cullin 9	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031461-&&-cullin-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CUL9				CUL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUL9	0.37366066	0.22222222	12	4	FALSE	CUL9	CUL9	308.1	0	11	0	0.72062917	FALSE	1	CUL9	7490	0.1430562
790249	taxon:9606	2.75200882	2.96E-06	173527	1902	SAM and SH3 domain containing 1	gene	biological_process-&-1&-GO:1901224-&&-positive regulation of NIK/NF-kappaB signaling-%%-GO:1900044-&&-regulation of protein K63-linked ubiquitination-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:1902498-&&-regulation of protein autoubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0031666-&&-positive regulation of lipopolysaccharide-mediated signaling pathway-%%-GO:1900745-&&-positive regulation of p38MAPK cascade|cellular_component-&-1&-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0019901-&&-protein kinase binding	G:9606:SASH1				SASH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SASH1	0.36337093	0.3030303	12	5	FALSE	SASH1	SASH1	204.0833333	0	12	0	0.70799853	FALSE	0	SASH1	6476	0.12097412
790288	taxon:9606	2.74161021	2.46E-06	173416	1902	PHD finger protein 3	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function	G:9606:PHF3				PHF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF3	0.36474915	0.04545455	12	5	FALSE	PHF3	PHF3	230.8333333	0	12	0	0.70973163	FALSE	0	PHF3	7394	0.13116932
790336	taxon:9606	2.82495667	4.69E-06	173289	1902	SEC31 homolog B, COPII coat complex component	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0016192-&&-vesicle-mediated transport|cellular_component-&-1&-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030120-&&-vesicle coat	G:9606:SEC31B			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC31B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC31B	0.35398773	0.48484848	12	4	FALSE	SEC31B	SEC31B	220.75	0	12	0	0.69584055	FALSE	0	SEC31B	6180	0.16424671
790353	taxon:9606	2.74838506	4.41E-06	173247	1902	leucine rich repeats and immunoglobulin like domains 1	gene	biological_process-&-1&-GO:0032474-&&-otolith morphogenesis-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0060384-&&-innervation-%%-GO:0022405-&&-hair cycle process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:LRIG1				LRIG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRIG1	0.36385003	0.33333333	12	4	FALSE	LRIG1	LRIG1	207.9166667	0	12	0	0.70860249	FALSE	0	LRIG1	7340	0.12156232
790448	taxon:9606	2.63951473	5.71E-06	172834	1902	SHC adaptor protein 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005515-&&-protein binding	G:9606:SHC2			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa01522-&&-Endocrine resistance-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa05034-&&-Alcoholism-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SHC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHC2	0.37885752	0.3030303	12	4	FALSE	SHC2	SHC2	301.25	0	12	0	0.72674754	FALSE	0	SHC2	17710	0.12609879
790485	taxon:9606	2.80006302	4.66E-06	172727	1902	zinc finger and BTB domain containing 20	gene	biological_process-&-1&-GO:0032728-&&-positive regulation of interferon-beta production-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZBTB20				ZBTB20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB20	0.35713482	0.42424242	12	5	FALSE	ZBTB20	ZBTB20	206.5833333	0	12	0	0.6999895	FALSE	0	ZBTB20	7568	0.14707977
790497	taxon:9606	3.00252088	3.19E-06	172685	1902	beta-1,3-glucuronyltransferase 3	gene	biological_process-&-1&-GO:0050651-&&-dermatan sulfate proteoglycan biosynthetic process-%%-GO:0006486-&&-protein glycosylation-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0015012-&&-heparan sulfate proteoglycan biosynthetic process-%%-GO:0030204-&&-chondroitin sulfate metabolic process-%%-GO:0050650-&&-chondroitin sulfate proteoglycan biosynthetic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0030203-&&-glycosaminoglycan metabolic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005801-&&-cis-Golgi network|molecular_function-&-1&-GO:0015020-&&-glucuronosyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0072542-&&-protein phosphatase activator activity-%%-GO:0015018-&&-galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity-%%-GO:0046872-&&-metal ion binding	G:9606:B3GAT3			KEGG-&-1&-hsa00532-&&-Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	B3GAT3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B3GAT3	0.33305347	0.06666667	12	5	FALSE	B3GAT3	B3GAT3	53.3	0	11	0	0.66624652	FALSE	1	B3GAT3	3382	0.11604396
790570	taxon:9606	2.91570821	1.02E-05	172104	1902	zinc finger and BTB domain containing 32	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0042769-&&-DNA damage response, detection of DNA damage-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ZBTB32				ZBTB32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB32	0.34296985	0.10606061	12	5	FALSE	ZBTB32	ZBTB32	85.33333333	0	12	0	0.6807153	FALSE	0	ZBTB32	9626	0.10401385
790591	taxon:9606	2.63620608	1.01E-05	172048	1902	copine 7	gene	biological_process-&-1&-GO:0046474-&&-glycerophospholipid biosynthetic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006810-&&-transport-%%-GO:0071277-&&-cellular response to calcium ion|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:CPNE7				CPNE7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPNE7	0.37933301	0.10606061	12	4	FALSE	CPNE7	CPNE7	385.6666667	0	12	0	0.72729899	FALSE	0	CPNE7	19638	0.16078881
790619	taxon:9606	2.87899795	4.22E-06	171737	1902	cysteine sulfinic acid decarboxylase	gene	biological_process-&-1&-GO:0019752-&&-carboxylic acid metabolic process-%%-GO:0042412-&&-taurine biosynthetic process|molecular_function-&-1&-GO:0004782-&&-sulfinoalanine decarboxylase activity-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:CSAD			KEGG-&-1&-hsa00430-&&-Taurine and hypotaurine metabolism-%%-hsa01100-&&-Metabolic pathways	CSAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSAD	0.34734307	0.07575758	12	4	FALSE	CSAD	CSAD	144.75	0	12	0	0.68683367	FALSE	0	CSAD	7334	0.14570707
790641	taxon:9606	2.73042382	1.01E-05	171685	1902	family with sequence similarity 193 member B	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm	G:9606:FAM193B				FAM193B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM193B	0.36624351	0.04545455	12	4	FALSE	FAM193B	FAM193B	201	0	12	0	0.71159603	FALSE	0	FAM193B	16830	0.10905462
790713	taxon:9606	2.93918387	3.05E-06	171407	1902	host cell factor C2	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity	G:9606:HCFC2			KEGG-&-1&-hsa05168-&&-Herpes simplex infection	HCFC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HCFC2	0.3402305	0.33333333	12	5	FALSE	HCFC2	HCFC2	98.33333333	0	12	0	0.67680269	FALSE	0	HCFC2	4890	0.12893701
790787	taxon:9606	2.75374193	4.27E-06	171201	1902	replication protein A4	gene	biological_process-&-1&-GO:0000082-&&-G1/S transition of mitotic cell cycle-%%-GO:0033260-&&-nuclear DNA replication-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006270-&&-DNA replication initiation-%%-GO:0006310-&&-DNA recombination-%%-GO:0000077-&&-DNA damage checkpoint|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005662-&&-DNA replication factor A complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding	G:9606:RPA4			KEGG-&-1&-hsa03430-&&-Mismatch repair-%%-hsa03030-&&-DNA replication-%%-hsa03440-&&-Homologous recombination-%%-hsa03460-&&-Fanconi anemia pathway-%%-hsa03420-&&-Nucleotide excision repair	RPA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPA4	0.36314224	0.42424242	12	5	FALSE	RPA4	RPA4	239.6666667	0	12	0	0.70770968	FALSE	0	RPA4	9052	0.14147973
790846	taxon:9606	2.61887506	6.78E-06	170966	1902	bromodomain and WD repeat domain containing 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006325-&&-chromatin organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:BRWD1				BRWD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRWD1	0.38184334	0.25757576	12	4	FALSE	BRWD1	BRWD1	317.4166667	0	12	0	0.73018749	FALSE	0	BRWD1	17360	0.12799301
790973	taxon:9606	2.81424295	5.34E-06	170546	1902	WD repeat domain, phosphoinositide interacting 1	gene	biological_process-&-1&-GO:0006914-&&-autophagy-%%-GO:0016236-&&-macroautophagy-%%-GO:0048203-&&-vesicle targeting, trans-Golgi to endosome-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0000421-&&-autophagosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0034045-&&-pre-autophagosomal structure membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0080025-&&-phosphatidylinositol-3,5-bisphosphate binding-%%-GO:0030331-&&-estrogen receptor binding	G:9606:WIPI1			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04136-&&-Autophagy - other	WIPI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WIPI1	0.35533535	0.12121212	12	5	FALSE	WIPI1	WIPI1	150.25	0	12	0	0.69762618	FALSE	0	WIPI1	7678	0.1147269
791008	taxon:9606	2.80400189	2.91E-05	170418	1902	FXYD domain containing ion transport regulator 6	gene	biological_process-&-1&-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity-%%-GO:0008150-&&-biological_process-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005216-&&-ion channel activity	G:9606:FXYD6				FXYD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FXYD6	0.35663314	0.04545455	12	4	FALSE	FXYD6	FXYD6	149.6666667	0	12	0	0.69933302	FALSE	0	FXYD6	28784	0.10447325
791076	taxon:9606	2.61162754	1.42E-05	170125	1902	RCC1 and BTB domain containing protein 1	gene	biological_process-&-1&-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:RCBTB1				RCBTB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCBTB1	0.38290299	0.3030303	12	4	FALSE	RCBTB1	RCBTB1	387.75	0	12	0	0.73139541	FALSE	0	RCBTB1	24732	0.15370885
791128	taxon:9606	2.60768867	1.76E-05	169951	1902	LanC like 2	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009789-&&-positive regulation of abscisic acid-activated signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0010314-&&-phosphatidylinositol-5-phosphate binding-%%-GO:0070273-&&-phosphatidylinositol-4-phosphate binding-%%-GO:0003824-&&-catalytic activity	G:9606:LANCL2				LANCL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LANCL2	0.38348136	0.09090909	12	4	FALSE	LANCL2	LANCL2	294.3333333	0	12	0	0.73205189	FALSE	0	LANCL2	27456	0.11485606
791147	taxon:9606	2.6051678	8.66E-06	169885	1902	leucine rich repeat containing 40	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane	G:9606:LRRC40				LRRC40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRC40	0.38385243	0.16666667	12	4	FALSE	LRRC40	LRRC40	387.5	0	12	0	0.73247203	FALSE	0	LRRC40	16528	0.14980005
791303	taxon:9606	2.76634631	7.91E-06	169280	1902	dihydropyrimidinase like 5	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0016810-&&-hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:DPYSL5			KEGG-&-1&-hsa04360-&&-Axon guidance	DPYSL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPYSL5	0.36148764	0.17777778	12	4	FALSE	DPYSL5	DPYSL5	190.3	0	11	0	0.70560895	FALSE	1	DPYSL5	12260	0.11383234
791341	taxon:9606	2.71246258	5.07E-05	169081	1902	VANGL planar cell polarity protein 2	gene	biological_process-&-1&-GO:0045176-&&-apical protein localization-%%-GO:0060489-&&-planar dichotomous subdivision of terminal units involved in lung branching morphogenesis-%%-GO:0001947-&&-heart looping-%%-GO:0032835-&&-glomerulus development-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:1904938-&&-planar cell polarity pathway involved in axon guidance-%%-GO:0003150-&&-muscular septum morphogenesis-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0015012-&&-heparan sulfate proteoglycan biosynthetic process-%%-GO:0060488-&&-orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis-%%-GO:0035787-&&-cell migration involved in kidney development-%%-GO:0001736-&&-establishment of planar polarity-%%-GO:0048103-&&-somatic stem cell division-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0048105-&&-establishment of body hair planar orientation-%%-GO:0001843-&&-neural tube closure-%%-GO:0003402-&&-planar cell polarity pathway involved in axis elongation-%%-GO:0036515-&&-serotonergic neuron axon guidance-%%-GO:0060993-&&-kidney morphogenesis-%%-GO:0001942-&&-hair follicle development-%%-GO:0042060-&&-wound healing-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0060028-&&-convergent extension involved in axis elongation-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0048546-&&-digestive tract morphogenesis-%%-GO:0060122-&&-inner ear receptor stereocilium organization-%%-GO:0060490-&&-lateral sprouting involved in lung morphogenesis-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0022007-&&-convergent extension involved in neural plate elongation-%%-GO:0061346-&&-planar cell polarity pathway involved in heart morphogenesis-%%-GO:0090177-&&-establishment of planar polarity involved in neural tube closure-%%-GO:0036514-&&-dopaminergic neuron axon guidance-%%-GO:0045197-&&-establishment or maintenance of epithelial cell apical/basal polarity-%%-GO:0030111-&&-regulation of Wnt signaling pathway-%%-GO:0036342-&&-post-anal tail morphogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0001725-&&-stress fiber-%%-GO:0030134-&&-ER to Golgi transport vesicle-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0060187-&&-cell pole|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:VANGL2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	VANGL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VANGL2	0.36866868	0.07575758	12	4	FALSE	VANGL2	VANGL2	205.25	0	12	0	0.71458957	FALSE	0	VANGL2	59312	0.1043257
791467	taxon:9606	2.7677643	4.46E-06	168520	1902	DExH-box helicase 58	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0045088-&&-regulation of innate immune response-%%-GO:1900246-&&-positive regulation of RIG-I signaling pathway-%%-GO:0039536-&&-negative regulation of RIG-I signaling pathway-%%-GO:1900245-&&-positive regulation of MDA-5 signaling pathway-%%-GO:0039534-&&-negative regulation of MDA-5 signaling pathway-%%-GO:0009615-&&-response to virus-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0051607-&&-defense response to virus-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0045824-&&-negative regulation of innate immune response|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004386-&&-helicase activity	G:9606:DHX58			KEGG-&-1&-hsa04622-&&-RIG-I-like receptor signaling pathway	DHX58	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX58	0.36130244	0.1969697	12	5	FALSE	DHX58	DHX58	167.9166667	0	12	0	0.70537262	FALSE	0	DHX58	8606	0.10556954
791592	taxon:9606	3.09106665	4.93E-06	167900	1902	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0035754-&&-B cell chemotaxis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003854-&&-3-beta-hydroxy-delta5-steroid dehydrogenase activity-%%-GO:0047016-&&-cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity-%%-GO:0005515-&&-protein binding	G:9606:HSD3B7	HSD3B7	TRUE	KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis	HSD3B7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD3B7	0.32351292	0.43939394	12	5	FALSE	HSD3B7	HSD3B7	78.25	0	12	0	0.65148889	FALSE	0	HSD3B7	5268	0.18352941
791794	taxon:9606	2.74602174	1.20E-05	166844	1902	ubiquinol-cytochrome c reductase complex assembly factor 2	gene	biological_process-&-1&-GO:0070131-&&-positive regulation of mitochondrial translation-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0034551-&&-mitochondrial respiratory chain complex III assembly-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0002082-&&-regulation of oxidative phosphorylation-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0016604-&&-nuclear body-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:UQCC2				UQCC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UQCC2	0.36416318	0.09090909	12	4	FALSE	UQCC2	UQCC2	201.75	0	12	0	0.70899638	FALSE	0	UQCC2	23170	0.11672457
791800	taxon:9606	2.66220262	8.84E-06	166806	1902	ADP ribosylation factor GTPase activating protein 2	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARFGAP2			KEGG-&-1&-hsa04144-&&-Endocytosis	ARFGAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGAP2	0.37562881	0.15151515	12	4	FALSE	ARFGAP2	ARFGAP2	263.9166667	0	12	0	0.72296623	FALSE	0	ARFGAP2	18468	0.11846442
791810	taxon:9606	2.77800536	4.71E-06	166771	1902	fibrillin 3	gene	biological_process-&-1&-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0090287-&&-regulation of cellular response to growth factor stimulus|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:FBN3	FBN3	TRUE		FBN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBN3	0.35997051	0.07575758	12	4	FALSE	FBN3	FBN3	176.1666667	0	12	0	0.70366577	FALSE	0	FBN3	12262	0.11708861
791857	taxon:9606	2.62564991	3.46E-06	182971	1902	active BCR-related	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0007420-&&-brain development-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0002692-&&-negative regulation of cellular extravasation-%%-GO:0043314-&&-negative regulation of neutrophil degranulation-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060313-&&-negative regulation of blood vessel remodeling|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity	G:9606:ABR				ABR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABR	0.38085809	0.21212121	12	4	FALSE	ABR	ABR	292.3333333	0	12	0	0.72905835	FALSE	0	ABR	12164	0.1192517
791877	taxon:9606	2.98881361	2.53E-06	182941	1902	adenosine kinase	gene	biological_process-&-1&-GO:0044209-&&-AMP salvage-%%-GO:0009156-&&-ribonucleoside monophosphate biosynthetic process-%%-GO:0006169-&&-adenosine salvage-%%-GO:0043101-&&-purine-containing compound salvage-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0006175-&&-dATP biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004001-&&-adenosine kinase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019200-&&-carbohydrate kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ADK			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	ADK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADK	0.33458092	0.25757576	12	4	FALSE	ADK	ADK	69.25	0	12	0	0.66853106	FALSE	0	ADK	3088	0.12575758
791881	taxon:9606	2.91665354	1.05E-05	166550	1902	WD repeat domain 73	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000922-&&-spindle pole-%%-GO:0032154-&&-cleavage furrow	G:9606:WDR73				WDR73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR73	0.34285869	0.03030303	12	5	FALSE	WDR73	WDR73	113.4166667	0	12	0	0.68055774	FALSE	0	WDR73	11878	0.14076155
791882	taxon:9606	2.89191744	7.48E-06	182928	1902	adrenoceptor alpha 1B	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0001994-&&-norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004937-&&-alpha1-adrenergic receptor activity	G:9606:ADRA1B	ADRA1B	TRUE	KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRA1B	0.34579134	0.04545455	12	4	FALSE	ADRA1B	ADRA1B	92.58333333	0	12	0	0.68468043	FALSE	0	ADRA1B	8954	0.1043322
791903	taxon:9606	2.6483378	1.84E-05	182900	1902	advanced glycosylation end-product specific receptor	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0072657-&&-protein localization to membrane-%%-GO:0009611-&&-response to wounding-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0071639-&&-positive regulation of monocyte chemotactic protein-1 production-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:1904597-&&-negative regulation of connective tissue replacement involved in inflammatory response wound healing-%%-GO:0031175-&&-neuron projection development-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0014002-&&-astrocyte development-%%-GO:1904604-&&-negative regulation of advanced glycation end-product receptor activity-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0001914-&&-regulation of T cell mediated cytotoxicity-%%-GO:2000514-&&-regulation of CD4-positive, alpha-beta T cell activation-%%-GO:0006954-&&-inflammatory response-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:2001200-&&-positive regulation of dendritic cell differentiation-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0051101-&&-regulation of DNA binding|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0001650-&&-fibrillar center-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0044548-&&-S100 protein binding-%%-GO:1904599-&&-advanced glycation end-product binding-%%-GO:0008201-&&-heparin binding-%%-GO:0042802-&&-identical protein binding	G:9606:AGER	AGER	TRUE	KEGG-&-1&-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications	AGER	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGER	0.37759534	0.15151515	12	5	FALSE	AGER	AGER	257.25	0	12	0	0.72527703	FALSE	0	AGER	23950	0.11206771
792012	taxon:9606	2.92090752	8.97E-06	182734	1902	bradykinin receptor B2	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0008015-&&-blood circulation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:0042311-&&-vasodilation-%%-GO:0009651-&&-response to salt stress-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:1902239-&&-negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator-%%-GO:0042310-&&-vasoconstriction-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:0019229-&&-regulation of vasoconstriction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0004947-&&-bradykinin receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:BDKRB2			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04610-&&-Complement and coagulation cascades	BDKRB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BDKRB2	0.34235935	0.09090909	12	4	FALSE	BDKRB2	BDKRB2	77.58333333	0	12	0	0.67984875	FALSE	0	BDKRB2	8628	0.10155907
792075	taxon:9606	2.674807	5.87E-06	182656	1902	tripeptidyl peptidase 1	gene	biological_process-&-1&-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0007399-&&-nervous system development-%%-GO:0006508-&&-proteolysis-%%-GO:0030163-&&-protein catabolic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0007040-&&-lysosome organization-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0043171-&&-peptide catabolic process-%%-GO:0045453-&&-bone resorption-%%-GO:0007417-&&-central nervous system development|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005764-&&-lysosome-%%-GO:0042470-&&-melanosome-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008240-&&-tripeptidyl-peptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008233-&&-peptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0046872-&&-metal ion binding	G:9606:TPP1			KEGG-&-1&-hsa04142-&&-Lysosome	TPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPP1	0.37385875	0.1969697	12	4	FALSE	TPP1	TPP1	265.9166667	0	12	0	0.7208655	FALSE	0	TPP1	12222	0.12326067
792127	taxon:9606	2.80809831	2.23E-05	182548	1902	acid phosphatase 2, lysosomal	gene	biological_process-&-1&-GO:0007040-&&-lysosome organization-%%-GO:0001501-&&-skeletal system development-%%-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005764-&&-lysosome-%%-GO:0016020-&&-membrane-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0003993-&&-acid phosphatase activity	G:9606:ACP2			KEGG-&-1&-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04142-&&-Lysosome	ACP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACP2	0.35611289	0.07575758	12	4	FALSE	ACP2	ACP2	140.9166667	0	12	0	0.69865028	FALSE	0	ACP2	22584	0.10291606
792171	taxon:9606	2.82810777	6.49E-06	166092	1902	hematological and neurological expressed 1 like	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus	G:9606:HN1L				HN1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HN1L	0.35359331	0.12121212	12	5	FALSE	HN1L	HN1L	144.6666667	0	12	0	0.69531537	FALSE	0	HN1L	8866	0.11284858
792191	taxon:9606	2.78667087	4.78E-06	182459	1902	Rho GTPase activating protein 5	gene	biological_process-&-1&-GO:0030879-&&-mammary gland development-%%-GO:0007155-&&-cell adhesion-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0042169-&&-SH2 domain binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARHGAP5			KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion	ARHGAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP5	0.35885113	0.16666667	12	4	FALSE	ARHGAP5	ARHGAP5	169.75	0	12	0	0.70222152	FALSE	0	ARHGAP5	9414	0.11673554
792216	taxon:9606	2.65983929	5.54E-06	166012	1902	schlafen family member 11	gene	biological_process-&-1&-GO:0051607-&&-defense response to virus-%%-GO:2000134-&&-negative regulation of G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000049-&&-tRNA binding	G:9606:SLFN11				SLFN11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLFN11	0.37596256	0.1969697	12	4	FALSE	SLFN11	SLFN11	302.25	0	12	0	0.72336012	FALSE	0	SLFN11	12856	0.13449837
792274	taxon:9606	2.87868284	4.16E-06	165926	1902	ATPase inhibitory factor 1	gene	biological_process-&-1&-GO:1901030-&&-positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway-%%-GO:1903578-&&-regulation of ATP metabolic process-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0009396-&&-folic acid-containing compound biosynthetic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006783-&&-heme biosynthetic process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0051882-&&-mitochondrial depolarization-%%-GO:1903052-&&-positive regulation of proteolysis involved in cellular protein catabolic process-%%-GO:1903214-&&-regulation of protein targeting to mitochondrion-%%-GO:0051346-&&-negative regulation of hydrolase activity-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:1904925-&&-positive regulation of mitophagy in response to mitochondrial depolarization-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0032780-&&-negative regulation of ATPase activity|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005739-&&-mitochondrion-%%-GO:0005753-&&-mitochondrial proton-transporting ATP synthase complex|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0030272-&&-5-formyltetrahydrofolate cyclo-ligase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042030-&&-ATPase inhibitor activity-%%-GO:0043532-&&-angiostatin binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:ATPIF1				ATPIF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATPIF1	0.3473811	0.08888889	12	4	FALSE	ATPIF1	ATPIF1	126.1	0	11	0	0.68688619	FALSE	1	ATPIF1	6914	0.12497512
792323	taxon:9606	2.83094375	3.31E-06	165847	1902	folliculin interacting protein 1	gene	biological_process-&-1&-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0031929-&&-TOR signaling-%%-GO:2000973-&&-regulation of pro-B cell differentiation-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0002327-&&-immature B cell differentiation-%%-GO:0002904-&&-positive regulation of B cell apoptotic process-%%-GO:0009267-&&-cellular response to starvation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0042030-&&-ATPase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:FNIP1			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	FNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FNIP1	0.35323909	0.22727273	12	4	FALSE	FNIP1	FNIP1	153.4166667	0	12	0	0.69484271	FALSE	0	FNIP1	7146	0.12322624
792345	taxon:9606	2.90452182	5.19E-05	182191	1902	cholinergic receptor muscarinic 3	gene	biological_process-&-1&-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0003056-&&-regulation of vascular smooth muscle contraction-%%-GO:0045987-&&-positive regulation of smooth muscle contraction-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006939-&&-smooth muscle contraction-%%-GO:0007197-&&-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0007207-&&-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0046541-&&-saliva secretion|cellular_component-&-1&-GO:0032279-&&-asymmetric synapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043679-&&-axon terminus-%%-GO:0045202-&&-synapse-%%-GO:0030425-&&-dendrite-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0016907-&&-G-protein coupled acetylcholine receptor activity-%%-GO:0042166-&&-acetylcholine binding-%%-GO:0008144-&&-drug binding-%%-GO:0005515-&&-protein binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0004872-&&-receptor activity	G:9606:CHRM3	CHRM3	TRUE	KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04911-&&-Insulin secretion-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion	CHRM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHRM3	0.34429075	0.06060606	12	5	FALSE	CHRM3	CHRM3	83.25	0	12	0	0.6825797	FALSE	0	CHRM3	72142	0.09689696
792455	taxon:9606	2.82306602	8.82E-06	181989	1902	coxsackie virus and adenovirus receptor	gene	biological_process-&-1&-GO:0048739-&&-cardiac muscle fiber development-%%-GO:0050900-&&-leukocyte migration-%%-GO:0086067-&&-AV node cell to bundle of His cell communication-%%-GO:0086072-&&-AV node cell-bundle of His cell adhesion involved in cell communication-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0008354-&&-germ cell migration-%%-GO:0070633-&&-transepithelial transport-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0098904-&&-regulation of AV node cell action potential-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007005-&&-mitochondrion organization-%%-GO:0045216-&&-cell-cell junction organization-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007507-&&-heart development-%%-GO:0010669-&&-epithelial structure maintenance-%%-GO:0046629-&&-gamma-delta T cell activation-%%-GO:0046718-&&-viral entry into host cell|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0016327-&&-apicolateral plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0044297-&&-cell body-%%-GO:0043234-&&-protein complex-%%-GO:0030426-&&-growth cone-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005911-&&-cell-cell junction-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043005-&&-neuron projection-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0030175-&&-filopodium|molecular_function-&-1&-GO:0071253-&&-connexin binding-%%-GO:0001618-&&-virus receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0086082-&&-cell adhesive protein binding involved in AV node cell-bundle of His cell communication-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005178-&&-integrin binding	G:9606:CXADR			KEGG-&-1&-hsa05416-&&-Viral myocarditis	CXADR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXADR	0.3542248	0.08888889	12	4	FALSE	CXADR	CXADR	169	0	11	0	0.69615566	FALSE	1	CXADR	13074	0.12657658
792470	taxon:9606	2.8356704	5.67E-06	181971	1902	alpha-2-glycoprotein 1, zinc-binding	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0071806-&&-protein transmembrane transport-%%-GO:0001895-&&-retina homeostasis-%%-GO:0090501-&&-RNA phosphodiester bond hydrolysis-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0007155-&&-cell adhesion-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001580-&&-detection of chemical stimulus involved in sensory perception of bitter taste|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008320-&&-protein transmembrane transporter activity-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0004540-&&-ribonuclease activity-%%-GO:0003823-&&-antigen binding-%%-GO:0005515-&&-protein binding	G:9606:AZGP1	AZGP1	TRUE		AZGP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AZGP1	0.35265029	0.04444444	12	4	FALSE	AZGP1	AZGP1	185.5	0	11	0	0.69405493	FALSE	1	AZGP1	10340	0.14460094
792499	taxon:9606	2.89617142	5.27E-06	165523	1902	F-box protein 32	gene	biological_process-&-1&-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0014894-&&-response to denervation involved in regulation of muscle adaptation-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO32			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FBXO32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO32	0.34528343	0.09090909	12	4	FALSE	FBXO32	FBXO32	98.33333333	0	12	0	0.68397143	FALSE	0	FBXO32	6990	0.10368217
792508	taxon:9606	2.95178825	3.00E-06	181890	1902	calcium voltage-gated channel subunit alpha1 B	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0007626-&&-locomotory behavior-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006810-&&-transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0048265-&&-response to pain-%%-GO:0051899-&&-membrane depolarization|cellular_component-&-1&-GO:0098793-&&-presynapse-%%-GO:0005886-&&-plasma membrane-%%-GO:0005891-&&-voltage-gated calcium channel complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0008331-&&-high voltage-gated calcium channel activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005245-&&-voltage-gated calcium channel activity	G:9606:CACNA1B			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04721-&&-Synaptic vesicle cycle	CACNA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACNA1B	0.33877769	0.06666667	12	4	FALSE	CACNA1B	CACNA1B	70	0	11	0	0.67470196	FALSE	1	CACNA1B	3452	0.12003454
792661	taxon:9606	2.81912715	2.51E-05	181608	1902	cytochrome P450 family 17 subfamily A member 1	gene	biological_process-&-1&-GO:0007548-&&-sex differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0016125-&&-sterol metabolic process-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0006694-&&-steroid biosynthetic process-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0042446-&&-hormone biosynthetic process-%%-GO:0006704-&&-glucocorticoid biosynthetic process|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030424-&&-axon-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0004508-&&-steroid 17-alpha-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0047442-&&-17-alpha-hydroxyprogesterone aldolase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0020037-&&-heme binding	G:9606:CYP17A1	CYP17A1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	CYP17A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP17A1	0.35471972	0.09090909	12	5	FALSE	CYP17A1	CYP17A1	139.4166667	0	12	0	0.69681214	FALSE	0	CYP17A1	22962	0.10833983
792674	taxon:9606	2.87789507	7.28E-06	181577	1902	diazepam binding inhibitor, acyl-CoA binding protein	gene	biological_process-&-1&-GO:0018345-&&-protein palmitoylation-%%-GO:0006810-&&-transport-%%-GO:0036151-&&-phosphatidylcholine acyl-chain remodeling-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0036042-&&-long-chain fatty acyl-CoA binding-%%-GO:0008289-&&-lipid binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0030156-&&-benzodiazepine receptor binding	G:9606:DBI			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	DBI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBI	0.34747619	0.12121212	12	4	FALSE	DBI	DBI	102.25	0	12	0	0.68701749	FALSE	0	DBI	9622	0.10633681
792784	taxon:9606	2.88372459	1.55E-05	181371	1902	cadherin EGF LAG seven-pass G-type receptor 2	gene	biological_process-&-1&-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0021999-&&-neural plate anterior/posterior regionalization-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0022407-&&-regulation of cell-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005509-&&-calcium ion binding	G:9606:CELSR2				CELSR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CELSR2	0.34677375	0.03030303	12	5	FALSE	CELSR2	CELSR2	101.4166667	0	12	0	0.6860459	FALSE	0	CELSR2	16962	0.10918294
792814	taxon:9606	2.78320466	4.57E-06	181327	1902	ELK4, ETS transcription factor	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030154-&&-cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070932-&&-histone H3 deacetylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003712-&&-transcription cofactor activity-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ELK4			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04010-&&-MAPK signaling pathway	ELK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELK4	0.35929805	0.15151515	12	5	FALSE	ELK4	ELK4	189.25	0	12	0	0.70279922	FALSE	0	ELK4	9712	0.12073743
792902	taxon:9606	2.90011029	8.91E-06	181198	1902	fatty acid binding protein 4	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0001816-&&-cytokine production-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0006810-&&-transport-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0071285-&&-cellular response to lithium ion-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0005811-&&-lipid particle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005504-&&-fatty acid binding	G:9606:FABP4	FABP4	TRUE	KEGG-&-1&-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa03320-&&-PPAR signaling pathway	FABP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FABP4	0.34481447	0.04545455	12	5	FALSE	FABP4	FABP4	83.91666667	0	12	0	0.68331495	FALSE	0	FABP4	9494	0.10401081
792921	taxon:9606	2.79691193	2.24E-05	181140	1902	glutamate decarboxylase 1	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0035176-&&-social behavior-%%-GO:0006538-&&-glutamate catabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0009449-&&-gamma-aminobutyric acid biosynthetic process-%%-GO:0018352-&&-protein-pyridoxal-5-phosphate linkage-%%-GO:0035641-&&-locomotory exploration behavior-%%-GO:0006540-&&-glutamate decarboxylation to succinate|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0060077-&&-inhibitory synapse-%%-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005622-&&-intracellular-%%-GO:0043679-&&-axon terminus-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0012506-&&-vesicle membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0016595-&&-glutamate binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0004351-&&-glutamate decarboxylase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:GAD1	GAD1	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00430-&&-Taurine and hypotaurine metabolism-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04727-&&-GABAergic synapse-%%-hsa00650-&&-Butanoate metabolism	GAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAD1	0.35753718	0.21212121	12	4	FALSE	GAD1	GAD1	179.6666667	0	12	0	0.70051468	FALSE	0	GAD1	22384	0.12781732
792922	taxon:9606	2.88120372	4.45E-06	181142	1902	gamma-aminobutyric acid type A receptor rho1 subunit	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0006810-&&-transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0034707-&&-chloride channel complex-%%-GO:1902711-&&-GABA-A receptor complex|molecular_function-&-1&-GO:0005254-&&-chloride channel activity-%%-GO:0004890-&&-GABA-A receptor activity-%%-GO:0005230-&&-extracellular ligand-gated ion channel activity	G:9606:GABRR1			KEGG-&-1&-hsa05032-&&-Morphine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GABRR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABRR1	0.34707716	0.04444444	12	4	FALSE	GABRR1	GABRR1	121.7	0	11	0	0.68646605	FALSE	1	GABRR1	5824	0.12938034
793029	taxon:9606	2.88088861	9.29E-06	180871	1902	glutamate ionotropic receptor AMPA type subunit 3	gene	biological_process-&-1&-GO:0007215-&&-glutamate receptor signaling pathway-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0006810-&&-transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0035235-&&-ionotropic glutamate receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030666-&&-endocytic vesicle membrane|molecular_function-&-1&-GO:0005234-&&-extracellular-glutamate-gated ion channel activity-%%-GO:0005231-&&-excitatory extracellular ligand-gated ion channel activity-%%-GO:0004971-&&-AMPA glutamate receptor activity	G:9606:GRIA3			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04730-&&-Long-term depression-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05031-&&-Amphetamine addiction	GRIA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIA3	0.34711512	0.15151515	12	4	FALSE	GRIA3	GRIA3	92.5	0	12	0	0.68651857	FALSE	0	GRIA3	10218	0.09864672
793044	taxon:9606	2.88293682	6.72E-06	180846	1902	glutamate metabotropic receptor 7	gene	biological_process-&-1&-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0030818-&&-negative regulation of cAMP biosynthetic process-%%-GO:0001661-&&-conditioned taste aversion-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0031279-&&-regulation of cyclase activity-%%-GO:0007196-&&-adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway-%%-GO:0030534-&&-adult behavior-%%-GO:0007614-&&-short-term memory-%%-GO:0001662-&&-behavioral fear response-%%-GO:0014050-&&-negative regulation of glutamate secretion-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0043198-&&-dendritic shaft-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0032279-&&-asymmetric synapse-%%-GO:0030425-&&-dendrite-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0008066-&&-glutamate receptor activity-%%-GO:0010855-&&-adenylate cyclase inhibitor activity-%%-GO:0005245-&&-voltage-gated calcium channel activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0001642-&&-group III metabotropic glutamate receptor activity-%%-GO:0070905-&&-serine binding	G:9606:GRM7			KEGG-&-1&-hsa04724-&&-Glutamatergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRM7	0.34686851	0.09090909	12	5	FALSE	GRM7	GRM7	107.0833333	0	12	0	0.6861772	FALSE	0	GRM7	9440	0.11565547
793076	taxon:9606	2.90074051	3.74E-06	180803	1902	general transcription factor IIH subunit 3	gene	biological_process-&-1&-GO:0000717-&&-nucleotide-excision repair, DNA duplex unwinding-%%-GO:0006362-&&-transcription elongation from RNA polymerase I promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006296-&&-nucleotide-excision repair, DNA incision, 5'-to lesion-%%-GO:0033683-&&-nucleotide-excision repair, DNA incision-%%-GO:0006293-&&-nucleotide-excision repair, preincision complex stabilization-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006295-&&-nucleotide-excision repair, DNA incision, 3'-to lesion-%%-GO:0006370-&&-7-methylguanosine mRNA capping-%%-GO:0070816-&&-phosphorylation of RNA polymerase II C-terminal domain-%%-GO:0006361-&&-transcription initiation from RNA polymerase I promoter-%%-GO:0006294-&&-nucleotide-excision repair, preincision complex assembly-%%-GO:0070911-&&-global genome nucleotide-excision repair-%%-GO:0006363-&&-termination of RNA polymerase I transcription-%%-GO:0006281-&&-DNA repair-%%-GO:0006283-&&-transcription-coupled nucleotide-excision repair-%%-GO:0006412-&&-translation-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter|cellular_component-&-1&-GO:0005669-&&-transcription factor TFIID complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000438-&&-core TFIIH complex portion of holo TFIIH complex-%%-GO:0005634-&&-nucleus-%%-GO:0097550-&&-transcriptional preinitiation complex-%%-GO:0005675-&&-holo TFIIH complex|molecular_function-&-1&-GO:0008353-&&-RNA polymerase II carboxy-terminal domain kinase activity-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0008094-&&-DNA-dependent ATPase activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003684-&&-damaged DNA binding	G:9606:GTF2H3			KEGG-&-1&-hsa03022-&&-Basal transcription factors-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa03420-&&-Nucleotide excision repair	GTF2H3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2H3	0.34473956	0.60606061	12	5	FALSE	GTF2H3	GTF2H3	142.9166667	0	12	0	0.68320992	FALSE	0	GTF2H3	8364	0.16022048
793122	taxon:9606	2.92516149	1.38E-05	180689	1902	beta-1,4-galactosyltransferase 1	gene	biological_process-&-1&-GO:0051270-&&-regulation of cellular component movement-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0002064-&&-epithelial cell development-%%-GO:0005989-&&-lactose biosynthetic process-%%-GO:0030879-&&-mammary gland development-%%-GO:0045136-&&-development of secondary sexual characteristics-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0060046-&&-regulation of acrosome reaction-%%-GO:0006012-&&-galactose metabolic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0007341-&&-penetration of zona pellucida-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0009312-&&-oligosaccharide biosynthetic process-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0060055-&&-angiogenesis involved in wound healing-%%-GO:0060054-&&-positive regulation of epithelial cell proliferation involved in wound healing-%%-GO:0060058-&&-positive regulation of apoptotic process involved in mammary gland involution|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030175-&&-filopodium-%%-GO:0030112-&&-glycocalyx-%%-GO:0030057-&&-desmosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0031526-&&-brush border membrane-%%-GO:0000138-&&-Golgi trans cisterna|molecular_function-&-1&-GO:0008378-&&-galactosyltransferase activity-%%-GO:0008092-&&-cytoskeletal protein binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0003945-&&-N-acetyllactosamine synthase activity-%%-GO:0035250-&&-UDP-galactosyltransferase activity-%%-GO:0003831-&&-beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity-%%-GO:0004461-&&-lactose synthase activity	G:9606:B4GALT1			KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa00510-&&-N-Glycan biosynthesis-%%-hsa00533-&&-Glycosaminoglycan biosynthesis - keratan sulfate-%%-hsa00515-&&-Mannose type O-glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00601-&&-Glycosphingolipid biosynthesis - lacto and neolacto series-%%-hsa00514-&&-Other types of O-glycan biosynthesis	B4GALT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B4GALT1	0.34186147	0.06666667	12	5	FALSE	B4GALT1	B4GALT1	98.1	0	11	0	0.67913975	FALSE	1	B4GALT1	19636	0.14323529
793148	taxon:9606	2.73578068	3.87E-06	180637	1902	glutamate dehydrogenase 2	gene	biological_process-&-1&-GO:0006536-&&-glutamate metabolic process-%%-GO:0006538-&&-glutamate catabolic process-%%-GO:0006537-&&-glutamate biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004353-&&-glutamate dehydrogenase [NAD(P)+] activity-%%-GO:0005525-&&-GTP binding-%%-GO:0043531-&&-ADP binding-%%-GO:0070728-&&-leucine binding-%%-GO:0004352-&&-glutamate dehydrogenase (NAD+) activity	G:9606:GLUD2			KEGG-&-1&-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa00471-&&-D-Glutamine and D-glutamate metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00910-&&-Nitrogen metabolism-%%-hsa04217-&&-Necroptosis	GLUD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLUD2	0.36552638	0.08888889	12	4	FALSE	GLUD2	GLUD2	258.4	0	11	0	0.71070322	FALSE	1	GLUD2	9184	0.14023926
793154	taxon:9606	2.74775484	5.07E-06	180624	1902	glia maturation factor beta	gene	biological_process-&-1&-GO:0007612-&&-learning-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0034316-&&-negative regulation of Arp2/3 complex-mediated actin nucleation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006469-&&-negative regulation of protein kinase activity|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0071933-&&-Arp2/3 complex binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:GMFB				GMFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMFB	0.36393349	0.10606061	12	5	FALSE	GMFB	GMFB	212.6666667	0	12	0	0.70870753	FALSE	0	GMFB	10566	0.12648987
793180	taxon:9606	2.96265952	1.14E-05	180578	1902	homeobox C9	gene	biological_process-&-1&-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016235-&&-aggresome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXC9				HOXC9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXC9	0.33753457	0.01515152	12	4	FALSE	HOXC9	HOXC9	55.33333333	0	12	0	0.67289008	FALSE	0	HOXC9	8862	0.09206081
793198	taxon:9606	2.70946904	1.52E-05	164162	1902	kelch like family member 23	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL23				KLHL23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL23	0.369076	0.12121212	12	4	FALSE	KLHL23	KLHL23	258.0833333	0	12	0	0.71508849	FALSE	0	KLHL23	21800	0.13240836
793231	taxon:9606	2.76540098	3.70E-06	164110	1902	ring finger protein 38	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0036126-&&-sperm flagellum|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:RNF38				RNF38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF38	0.36161121	0.28888889	12	4	FALSE	RNF38	RNF38	251.5	0	11	0	0.7057665	FALSE	1	RNF38	7210	0.15432781
793237	taxon:9606	2.66220262	3.31E-06	164098	1902	coiled-coil domain containing 50	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0005515-&&-protein binding	G:9606:CCDC50				CCDC50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC50	0.37562881	0.21212121	12	4	FALSE	CCDC50	CCDC50	270.9166667	0	12	0	0.72296623	FALSE	0	CCDC50	6836	0.12256677
793315	taxon:9606	2.79880258	5.91E-05	180327	1902	complement factor H	gene	biological_process-&-1&-GO:0006957-&&-complement activation, alternative pathway-%%-GO:0006956-&&-complement activation-%%-GO:0030449-&&-regulation of complement activation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0043395-&&-heparan sulfate proteoglycan binding-%%-GO:0005515-&&-protein binding-%%-GO:0008201-&&-heparin binding	G:9606:CFH	CFH	TRUE	KEGG-&-1&-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04610-&&-Complement and coagulation cascades	CFH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFH	0.35729565	0.13636364	12	4	FALSE	CFH	CFH	147.1666667	0	12	0	0.70019957	FALSE	0	CFH	56080	0.10536398
787095	taxon:9606	2.91444777	1.56E-05	180060	1902	interleukin 1 receptor type 1	gene	biological_process-&-1&-GO:0070555-&&-response to interleukin-1-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0070498-&&-interleukin-1-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:2000661-&&-positive regulation of interleukin-1-mediated signaling pathway-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:2000391-&&-positive regulation of neutrophil extravasation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009986-&&-cell surface-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0004909-&&-interleukin-1, Type I, activating receptor activity-%%-GO:0002020-&&-protease binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0004908-&&-interleukin-1 receptor activity-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:IL1R1	IL1R1	TRUE	KEGG-&-1&-hsa05146-&&-Amoebiasis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05163-&&-Human cytomegalovirus infection	IL1R1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1R1	0.34311817	0.29090909	11	5	FALSE	IL1R1	IL1R1	92.72727273	0	11	0	0.68092537	FALSE	0	IL1R1	14092	0.11394387
787109	taxon:9606	2.88214905	1.83E-05	180046	1902	interleukin 6 receptor	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0006953-&&-acute-phase response-%%-GO:0034097-&&-response to cytokine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0070120-&&-ciliary neurotrophic factor-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0002384-&&-hepatic immune response-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070110-&&-ciliary neurotrophic factor receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface-%%-GO:0005896-&&-interleukin-6 receptor complex|molecular_function-&-1&-GO:0004897-&&-ciliary neurotrophic factor receptor activity-%%-GO:0070119-&&-ciliary neurotrophic factor binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0005138-&&-interleukin-6 receptor binding-%%-GO:0004915-&&-interleukin-6 receptor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0019981-&&-interleukin-6 binding	G:9606:IL6R	IL6R	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04066-&&-HIF-1 signaling pathway	IL6R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL6R	0.34696332	0.19444444	11	5	FALSE	IL6R	IL6R	130.6666667	0	10	0	0.68630849	FALSE	1	IL6R	17096	0.13850514
787119	taxon:9606	2.98093588	3.92E-05	180028	1902	interleukin 12 receptor subunit beta 1	gene	biological_process-&-1&-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0002827-&&-positive regulation of T-helper 1 type immune response-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:2000330-&&-positive regulation of T-helper 17 cell lineage commitment-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:0007165-&&-signal transduction-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0035722-&&-interleukin-12-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043382-&&-positive regulation of memory T cell differentiation-%%-GO:0038155-&&-interleukin-23-mediated signaling pathway-%%-GO:2000318-&&-positive regulation of T-helper 17 type immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042022-&&-interleukin-12 receptor complex-%%-GO:0072536-&&-interleukin-23 receptor complex|molecular_function-&-1&-GO:0042020-&&-interleukin-23 receptor activity-%%-GO:0016517-&&-interleukin-12 receptor activity-%%-GO:0005143-&&-interleukin-12 receptor binding-%%-GO:0004896-&&-cytokine receptor activity-%%-GO:0042019-&&-interleukin-23 binding	G:9606:IL12RB1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL12RB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL12RB1	0.33546512	0.07272727	11	5	FALSE	IL12RB1	IL12RB1	66.81818182	0	11	0	0.66984402	FALSE	0	IL12RB1	64390	0.13589696
787137	taxon:9606	2.87017489	9.39E-06	163617	1902	zinc finger protein 746	gene	biological_process-&-1&-GO:1901216-&&-positive regulation of neuron death-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZNF746				ZNF746	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF746	0.34841083	0.01818182	11	4	FALSE	ZNF746	ZNF746	112.2727273	0	11	0	0.68830419	FALSE	0	ZNF746	9348	0.10894872
787164	taxon:9606	2.93004569	2.67E-06	179944	1902	lymphotoxin alpha	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0048535-&&-lymph node development-%%-GO:0007584-&&-response to nutrient-%%-GO:0007165-&&-signal transduction-%%-GO:0060252-&&-positive regulation of glial cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002876-&&-positive regulation of chronic inflammatory response to antigenic stimulus-%%-GO:0006959-&&-humoral immune response-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0002925-&&-positive regulation of humoral immune response mediated by circulating immunoglobulin|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005164-&&-tumor necrosis factor receptor binding	G:9606:LTA	LTA	TRUE	KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	LTA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTA	0.34129161	0.16666667	11	5	FALSE	LTA	LTA	107.6666667	0	10	0	0.67832572	FALSE	1	LTA	3852	0.15459632
787312	taxon:9606	2.97100993	2.86E-06	163298	1902	aristaless related homeobox	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0072148-&&-epithelial cell fate commitment-%%-GO:0021853-&&-cerebral cortex GABAergic interneuron migration-%%-GO:0021759-&&-globus pallidus development-%%-GO:0021800-&&-cerebral cortex tangential migration-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0044241-&&-lipid digestion-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0046622-&&-positive regulation of organ growth-%%-GO:0021846-&&-cell proliferation in forebrain-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0021831-&&-embryonic olfactory bulb interneuron precursor migration|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding-%%-GO:0001206-&&-transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding	G:9606:ARX				ARX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARX	0.33658588	0.32727273	11	5	FALSE	ARX	ARX	78.72727273	0	11	0	0.67149835	FALSE	0	ARX	3088	0.1391038
787337	taxon:9606	2.91555065	1.08E-05	179629	1902	laminin subunit alpha 3	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0008544-&&-epidermis development-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0031581-&&-hemidesmosome assembly-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0045995-&&-regulation of embryonic development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005604-&&-basement membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005610-&&-laminin-5 complex|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005198-&&-structural molecule activity	G:9606:LAMA3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04510-&&-Focal adhesion-%%-hsa05200-&&-Pathways in cancer-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	LAMA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LAMA3	0.34298838	0.05454545	11	4	FALSE	LAMA3	LAMA3	78.45454545	0	11	0	0.68074156	FALSE	0	LAMA3	9970	0.10499877
787377	taxon:9606	2.88041594	5.24E-06	179534	1902	myosin heavy chain 3	gene	biological_process-&-1&-GO:0045214-&&-sarcomere organization-%%-GO:0007517-&&-muscle organ development-%%-GO:0003009-&&-skeletal muscle contraction-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0060325-&&-face morphogenesis-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0030049-&&-muscle filament sliding|cellular_component-&-1&-GO:0030017-&&-sarcomere-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005859-&&-muscle myosin complex-%%-GO:0032982-&&-myosin filament-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0000146-&&-microfilament motor activity-%%-GO:0051015-&&-actin filament binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0017018-&&-myosin phosphatase activity	G:9606:MYH3			KEGG-&-1&-hsa04530-&&-Tight junction	MYH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYH3	0.34717208	0.10909091	11	4	FALSE	MYH3	MYH3	123.8181818	0	11	0	0.68659734	FALSE	0	MYH3	8924	0.12238456
787387	taxon:9606	2.85694029	7.68E-06	163134	1902	mixed lineage kinase domain like pseudokinase	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0070266-&&-necroptotic process-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:MLKL			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04217-&&-Necroptosis	MLKL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLKL	0.35002482	0.09090909	11	4	FALSE	MLKL	MLKL	120.2727273	0	11	0	0.69050995	FALSE	0	MLKL	8436	0.109423
787389	taxon:9606	2.90152828	4.11E-06	179512	1902	myosin VIIA	gene	biological_process-&-1&-GO:0042462-&&-eye photoreceptor cell development-%%-GO:0030048-&&-actin filament-based movement-%%-GO:0001845-&&-phagolysosome assembly-%%-GO:0007040-&&-lysosome organization-%%-GO:0051904-&&-pigment granule transport-%%-GO:0050953-&&-sensory perception of light stimulus-%%-GO:0050957-&&-equilibrioception-%%-GO:0060088-&&-auditory receptor cell stereocilium organization-%%-GO:0007601-&&-visual perception-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0048563-&&-post-embryonic animal organ morphogenesis-%%-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0032420-&&-stereocilium-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005938-&&-cell cortex-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0005902-&&-microvillus-%%-GO:0016324-&&-apical plasma membrane-%%-GO:1990435-&&-upper tip-link density-%%-GO:0031477-&&-myosin VII complex-%%-GO:0042470-&&-melanosome-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0000146-&&-microfilament motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0030507-&&-spectrin binding-%%-GO:0043531-&&-ADP binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0030898-&&-actin-dependent ATPase activity-%%-GO:0047485-&&-protein N-terminus binding-%%-GO:0005524-&&-ATP binding-%%-GO:0051015-&&-actin filament binding	G:9606:MYO7A				MYO7A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO7A	0.34464596	0.07272727	11	5	FALSE	MYO7A	MYO7A	102.7272727	0	11	0	0.68307862	FALSE	0	MYO7A	5230	0.11816077
787401	taxon:9606	2.99369781	5.00E-06	179492	1902	NLR family apoptosis inhibitory protein	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006915-&&-apoptotic process-%%-GO:0090307-&&-mitotic spindle assembly-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006954-&&-inflammatory response-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0007399-&&-nervous system development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043200-&&-response to amino acid-%%-GO:0048678-&&-response to axon injury-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:NAIP			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05134-&&-Legionellosis	NAIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAIP	0.33403505	0.05555556	11	5	FALSE	NAIP	NAIP	61.22222222	0	10	0	0.66771703	FALSE	1	NAIP	4458	0.12990721
787439	taxon:9606	2.79896014	8.34E-06	179433	1902	leukemia inhibitory factor receptor alpha	gene	biological_process-&-1&-GO:0038165-&&-oncostatin-M-mediated signaling pathway-%%-GO:0070120-&&-ciliary neurotrophic factor-mediated signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048861-&&-leukemia inhibitory factor signaling pathway-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005127-&&-ciliary neurotrophic factor receptor binding-%%-GO:0004924-&&-oncostatin-M receptor activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0004923-&&-leukemia inhibitory factor receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004897-&&-ciliary neurotrophic factor receptor activity	G:9606:LIFR			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	LIFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIFR	0.35727554	0.10909091	11	4	FALSE	LIFR	LIFR	160	0	11	0	0.70017331	FALSE	0	LIFR	12180	0.11603306
787469	taxon:9606	2.86009138	1.22E-05	179373	1902	microsomal glutathione S-transferase 3	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005635-&&-nuclear envelope-%%-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0004601-&&-peroxidase activity-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0005515-&&-protein binding	G:9606:MGST3			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05204-&&-Chemical carcinogenesis	MGST3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGST3	0.34963918	0.09090909	11	5	FALSE	MGST3	MGST3	127.8181818	0	11	0	0.68998477	FALSE	0	MGST3	13860	0.11009751
787520	taxon:9606	2.89160233	7.96E-06	162900	1902	ADP ribosylation factor like GTPase 13B	gene	biological_process-&-1&-GO:0007224-&&-smoothened signaling pathway-%%-GO:0021532-&&-neural tube patterning-%%-GO:1905515-&&-non-motile cilium assembly-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0001947-&&-heart looping-%%-GO:0010226-&&-response to lithium ion-%%-GO:0021830-&&-interneuron migration from the subpallium to the cortex-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0021943-&&-formation of radial glial scaffolds-%%-GO:0070986-&&-left/right axis specification-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0005929-&&-cilium-%%-GO:0060170-&&-ciliary membrane-%%-GO:0031514-&&-motile cilium|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:ARL13B				ARL13B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARL13B	0.34582902	0.03636364	11	4	FALSE	ARL13B	ARL13B	96.81818182	0	11	0	0.68473294	FALSE	0	ARL13B	8798	0.10321258
787526	taxon:9606	2.71325035	4.17E-06	179257	1902	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1	gene	biological_process-&-1&-GO:0001570-&&-vasculogenesis-%%-GO:0043473-&&-pigmentation-%%-GO:0003340-&&-negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0006915-&&-apoptotic process-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0070741-&&-response to interleukin-6-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0051591-&&-response to cAMP-%%-GO:0001890-&&-placenta development-%%-GO:0071105-&&-response to interleukin-11-%%-GO:0006913-&&-nucleocytoplasmic transport-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060712-&&-spongiotrophoblast layer development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071104-&&-response to interleukin-9-%%-GO:0000578-&&-embryonic axis specification-%%-GO:0032868-&&-response to insulin-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0007420-&&-brain development-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0043627-&&-response to estrogen-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0070669-&&-response to interleukin-2-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0001656-&&-metanephros development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0060711-&&-labyrinthine layer development-%%-GO:0071107-&&-response to parathyroid hormone-%%-GO:0008283-&&-cell proliferation-%%-GO:0042438-&&-melanin biosynthetic process-%%-GO:0070670-&&-response to interleukin-4|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0070410-&&-co-SMAD binding-%%-GO:0050693-&&-LBD domain binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:CITED1				CITED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CITED1	0.36856164	0.41818182	11	4	FALSE	CITED1	CITED1	278	0	11	0	0.71445827	FALSE	0	CITED1	7652	0.14537843
787549	taxon:9606	3.05025997	1.38E-05	179205	1902	macrophage stimulating 1	gene	biological_process-&-1&-GO:0045721-&&-negative regulation of gluconeogenesis-%%-GO:0006508-&&-proteolysis-%%-GO:2000479-&&-regulation of cAMP-dependent protein kinase activity-%%-GO:0008150-&&-biological_process-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005515-&&-protein binding	G:9606:MST1				MST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MST1	0.32784091	0.08333333	11	5	FALSE	MST1	MST1	39.55555556	0	10	0	0.65829001	FALSE	1	MST1	19790	0.12871287
787585	taxon:9606	2.85631007	6.61E-06	179143	1902	neurofilament heavy	gene	biological_process-&-1&-GO:0030031-&&-cell projection assembly-%%-GO:0061564-&&-axon development-%%-GO:1902513-&&-regulation of organelle transport along microtubule-%%-GO:0007409-&&-axonogenesis-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0033693-&&-neurofilament bundle assembly-%%-GO:0048936-&&-peripheral nervous system neuron axonogenesis|cellular_component-&-1&-GO:0043209-&&-myelin sheath-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0005739-&&-mitochondrion-%%-GO:0097418-&&-neurofibrillary tangle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005883-&&-neurofilament|molecular_function-&-1&-GO:0070840-&&-dynein complex binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0008017-&&-microtubule binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0019894-&&-kinesin binding	G:9606:NEFH			KEGG-&-1&-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)	NEFH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEFH	0.35010205	0.10909091	11	5	FALSE	NEFH	NEFH	119	0	11	0	0.69061499	FALSE	0	NEFH	8510	0.10882426
787665	taxon:9606	2.68583583	5.47E-05	178989	1902	serpin family B member 6	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0071470-&&-cellular response to osmotic stress-%%-GO:0007605-&&-sensory perception of sound|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0043234-&&-protein complex-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding	G:9606:SERPINB6			KEGG-&-1&-hsa05146-&&-Amoebiasis	SERPINB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB6	0.37232358	0.14545455	11	4	FALSE	SERPINB6	SERPINB6	246.8181818	0	11	0	0.71902736	FALSE	0	SERPINB6	50692	0.1170557
787715	taxon:9606	2.84622656	5.42E-06	178899	1902	phorbol-12-myristate-13-acetate-induced protein 1	gene	biological_process-&-1&-GO:0071456-&&-cellular response to hypoxia-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0043331-&&-response to dsRNA-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:1902237-&&-positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process-%%-GO:0032461-&&-positive regulation of protein oligomerization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001836-&&-release of cytochrome c from mitochondria-%%-GO:0001844-&&-protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0010917-&&-negative regulation of mitochondrial membrane potential-%%-GO:1900740-&&-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0046902-&&-regulation of mitochondrial membrane permeability-%%-GO:0051607-&&-defense response to virus-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:1902043-&&-positive regulation of extrinsic apoptotic signaling pathway via death domain receptors-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0043029-&&-T cell homeostasis|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PMAIP1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis-%%-hsa05203-&&-Viral carcinogenesis-%%-hsa05210-&&-Colorectal cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance	PMAIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMAIP1	0.35134237	0.21818182	11	4	FALSE	PMAIP1	PMAIP1	134.8181818	0	11	0	0.69229557	FALSE	0	PMAIP1	8586	0.11738131
787856	taxon:9606	2.86718135	2.52E-05	178711	1902	protein S (alpha)	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006465-&&-signal peptide processing-%%-GO:0042730-&&-fibrinolysis-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0030449-&&-regulation of complement activation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0005509-&&-calcium ion binding	G:9606:PROS1			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	PROS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PROS1	0.34877459	0.16363636	11	5	FALSE	PROS1	PROS1	125.2727273	0	11	0	0.68880311	FALSE	0	PROS1	28124	0.11803588
787861	taxon:9606	2.79250039	1.42E-05	178693	1902	kallikrein related peptidase 7	gene	biological_process-&-1&-GO:0002803-&&-positive regulation of antibacterial peptide production-%%-GO:0008544-&&-epidermis development-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0097209-&&-epidermal lamellar body-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0008233-&&-peptidase activity	G:9606:KLK7				KLK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK7	0.35810201	0.07272727	11	5	FALSE	KLK7	KLK7	158.8181818	0	11	0	0.70124993	FALSE	0	KLK7	15826	0.10759533
787962	taxon:9606	2.83803372	4.47E-06	178502	1902	paired box 7	gene	biological_process-&-1&-GO:2000288-&&-positive regulation of myoblast proliferation-%%-GO:0048706-&&-embryonic skeletal system development-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0014813-&&-skeletal muscle satellite cell commitment-%%-GO:0021527-&&-spinal cord association neuron differentiation-%%-GO:0031062-&&-positive regulation of histone methylation-%%-GO:0048663-&&-neuron fate commitment-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0021904-&&-dorsal/ventral neural tube patterning-%%-GO:0043403-&&-skeletal muscle tissue regeneration-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060415-&&-muscle tissue morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010453-&&-regulation of cell fate commitment-%%-GO:0051216-&&-cartilage development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:PAX7			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	PAX7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAX7	0.35235663	0.16363636	11	4	FALSE	PAX7	PAX7	165.4545455	0	11	0	0.69366105	FALSE	0	PAX7	9220	0.13784214
787982	taxon:9606	2.84890499	1.73E-05	178457	1902	phosphodiesterase 3B	gene	biological_process-&-1&-GO:0006198-&&-cAMP catabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0032869-&&-cellular response to insulin stimulus|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane-%%-GO:0032045-&&-guanyl-nucleotide exchange factor complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0004114-&&-3',5'-cyclic-nucleotide phosphodiesterase activity-%%-GO:0004119-&&-cGMP-inhibited cyclic-nucleotide phosphodiesterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004115-&&-3',5'-cyclic-AMP phosphodiesterase activity-%%-GO:0047555-&&-3',5'-cyclic-GMP phosphodiesterase activity	G:9606:PDE3B			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa00230-&&-Purine metabolism-%%-hsa04022-&&-cGMP-PKG signaling pathway	PDE3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDE3B	0.35101206	0.01818182	11	5	FALSE	PDE3B	PDE3B	136	0	11	0	0.69184917	FALSE	0	PDE3B	19182	0.1200549
787996	taxon:9606	2.9404443	3.32E-06	178433	1902	pyruvate dehydrogenase kinase 2	gene	biological_process-&-1&-GO:0006885-&&-regulation of pH-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0031670-&&-cellular response to nutrient-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0006111-&&-regulation of gluconeogenesis-%%-GO:0010510-&&-regulation of acetyl-CoA biosynthetic process from pyruvate-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0010565-&&-regulation of cellular ketone metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0005967-&&-mitochondrial pyruvate dehydrogenase complex-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004740-&&-pyruvate dehydrogenase (acetyl-transferring) kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004672-&&-protein kinase activity	G:9606:PDK2				PDK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDK2	0.34008466	0.36111111	11	5	FALSE	PDK2	PDK2	91.77777778	0	10	0	0.67659262	FALSE	1	PDK2	3708	0.13460597
788132	taxon:9606	2.68583583	2.32E-06	178194	1902	protein tyrosine phosphatase, receptor type R	gene	biological_process-&-1&-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:1903385-&&-regulation of homophilic cell adhesion-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0010633-&&-negative regulation of epithelial cell migration|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005001-&&-transmembrane receptor protein tyrosine phosphatase activity	G:9606:PTPRR			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PTPRR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRR	0.37232358	0.22222222	11	4	FALSE	PTPRR	PTPRR	306.5555556	0	10	0	0.71902736	FALSE	1	PTPRR	6082	0.1461514
788151	taxon:9606	2.80825587	7.11E-06	178153	1902	mitogen-activated protein kinase kinase kinase kinase 2	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0000185-&&-activation of MAPKKK activity-%%-GO:0006903-&&-vesicle targeting-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006955-&&-immune response-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0007254-&&-JNK cascade-%%-GO:0046330-&&-positive regulation of JNK cascade|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0031435-&&-mitogen-activated protein kinase kinase kinase binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0008349-&&-MAP kinase kinase kinase kinase activity	G:9606:MAP4K2			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP4K2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP4K2	0.35609291	0.16363636	11	5	FALSE	MAP4K2	MAP4K2	157.2727273	0	11	0	0.69862402	FALSE	0	MAP4K2	8488	0.11771125
788170	taxon:9606	2.77012762	5.76E-06	178134	1902	MOK protein kinase	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0097546-&&-ciliary base-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity	G:9606:MOK				MOK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOK	0.3609942	0.05454545	11	4	FALSE	MOK	MOK	181.5454546	0	11	0	0.70497873	FALSE	0	MOK	9526	0.11471724
788185	taxon:9606	2.8457539	8.66E-06	178115	1902	RAP2B, member of RAS oncogene family	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0070527-&&-platelet aggregation-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0030033-&&-microvillus assembly-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0007165-&&-signal transduction-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0061097-&&-regulation of protein tyrosine kinase activity-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0045121-&&-membrane raft-%%-GO:0016020-&&-membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:RAP2B				RAP2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP2B	0.35140073	0.12727273	11	5	FALSE	RAP2B	RAP2B	201.8181818	0	11	0	0.69237435	FALSE	0	RAP2B	13248	0.16566986
788234	taxon:9606	2.69623444	1.07E-05	161648	1902	kallikrein related peptidase 9	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity	G:9606:KLK9				KLK9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLK9	0.37088763	0.10909091	11	4	FALSE	KLK9	KLK9	233.9090909	0	11	0	0.71729426	FALSE	0	KLK9	20586	0.11699367
788257	taxon:9606	2.79706948	1.09E-05	177995	1902	regulator of G-protein signaling 16	gene	biological_process-&-1&-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0007601-&&-visual perception-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0031224-&&-intrinsic component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:RGS16				RGS16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS16	0.35751704	0.25454545	11	4	FALSE	RGS16	RGS16	170.3636364	0	11	0	0.70048842	FALSE	0	RGS16	12536	0.12112585
788318	taxon:9606	3.03072318	7.28E-06	177896	1902	S100 calcium binding protein A13	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0050663-&&-cytokine secretion-%%-GO:0043303-&&-mast cell degranulation-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0046688-&&-response to copper ion-%%-GO:0050703-&&-interleukin-1 alpha secretion-%%-GO:0051602-&&-response to electrical stimulus|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0042629-&&-mast cell granule-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0050786-&&-RAGE receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005507-&&-copper ion binding-%%-GO:0008289-&&-lipid binding-%%-GO:0008270-&&-zinc ion binding	G:9606:S100A13				S100A13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S100A13	0.32995425	0	11	5	FALSE	S100A13	S100A13	49.77777778	0	10	0	0.66154614	FALSE	1	S100A13	5960	0.11613757
788382	taxon:9606	2.79801481	1.34E-05	177770	1902	somatostatin receptor 3	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0008628-&&-hormone-mediated apoptotic signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0021549-&&-cerebellum development-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0038170-&&-somatostatin signaling pathway-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0042594-&&-response to starvation-%%-GO:0030900-&&-forebrain development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0097730-&&-non-motile cilium-%%-GO:0043005-&&-neuron projection-%%-GO:0005737-&&-cytoplasm-%%-GO:0060170-&&-ciliary membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0042923-&&-neuropeptide binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004994-&&-somatostatin receptor activity	G:9606:SSTR3			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	SSTR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSTR3	0.35739625	0.09090909	11	4	FALSE	SSTR3	SSTR3	153.8181818	0	11	0	0.70033086	FALSE	0	SSTR3	16092	0.10783875
788414	taxon:9606	2.97542146	6.70E-06	177712	1902	selectin P ligand	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0007155-&&-cell adhesion-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0050902-&&-leukocyte adhesive activation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0001931-&&-uropod|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:SELPLG			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05150-&&-Staphylococcus aureus infection	SELPLG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELPLG	0.33608684	0.16666667	11	5	FALSE	SELPLG	SELPLG	73.11111111	0	10	0	0.67076309	FALSE	1	SELPLG	6486	0.13300892
788434	taxon:9606	2.9700646	6.34E-06	144910	1902	MSANTD3-TMEFF1 readthrough	gene		G:9606:MSANTD3-TMEFF1				MSANTD3-TMEFF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSANTD3-TMEFF1	0.33669301	0.01818182	11	5	FALSE	MSANTD3-TMEFF1	MSANTD3-TMEFF1	62.45454545	0	11	0	0.6716559	FALSE	0	MSANTD3-TMEFF1	7722	0.1199151
788435	taxon:9606	2.71072948	5.57E-05	144905	1902	APITD1-CORT readthrough	gene		G:9606:APITD1-CORT			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	APITD1-CORT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APITD1-CORT	0.36890439	0.36363636	11	4	FALSE	APITD1-CORT	APITD1-CORT	247.2727273	0	11	0	0.71487842	FALSE	0	APITD1-CORT	71110	0.12787471
788460	taxon:9606	2.8523712	3.24E-06	177614	1902	solute carrier family 12 member 3	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0006814-&&-sodium ion transport-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0015378-&&-sodium:chloride symporter activity-%%-GO:0005515-&&-protein binding	G:9606:SLC12A3				SLC12A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC12A3	0.35058551	0.29090909	11	4	FALSE	SLC12A3	SLC12A3	170.1818182	0	11	0	0.69127147	FALSE	0	SLC12A3	4954	0.15691043
788521	taxon:9606	2.67638254	6.63E-06	177514	1902	Sp2 transcription factor	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006955-&&-immune response-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:SP2				SP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP2	0.37363866	0.14545455	11	4	FALSE	SP2	SP2	251.0909091	0	11	0	0.72060291	FALSE	0	SP2	14316	0.11716228
788669	taxon:9606	2.89884985	2.56E-05	177221	1902	TIMP metallopeptidase inhibitor 1	gene	biological_process-&-1&-GO:1901164-&&-negative regulation of trophoblast cell migration-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:2001044-&&-regulation of integrin-mediated signaling pathway-%%-GO:0001775-&&-cell activation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0034097-&&-response to cytokine-%%-GO:0002576-&&-platelet degranulation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:1905049-&&-negative regulation of metallopeptidase activity-%%-GO:0007568-&&-aging-%%-GO:0051216-&&-cartilage development-%%-GO:0009725-&&-response to hormone-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0002020-&&-protease binding-%%-GO:0046872-&&-metal ion binding	G:9606:TIMP1	TIMP1	TRUE	KEGG-&-1&-hsa04066-&&-HIF-1 signaling pathway	TIMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMP1	0.3449644	0.01818182	11	5	FALSE	TIMP1	TIMP1	96	0	11	0	0.68352502	FALSE	0	TIMP1	29448	0.10670607
788777	taxon:9606	2.81487317	6.07E-05	176917	1902	paired box 8	gene	biological_process-&-1&-GO:0030878-&&-thyroid gland development-%%-GO:0072221-&&-metanephric distal convoluted tubule development-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0001655-&&-urogenital system development-%%-GO:0001823-&&-mesonephros development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1900212-&&-negative regulation of mesenchymal cell apoptotic process involved in metanephros development-%%-GO:0007417-&&-central nervous system development-%%-GO:0071371-&&-cellular response to gonadotropin stimulus-%%-GO:2000611-&&-positive regulation of thyroid hormone generation-%%-GO:0001822-&&-kidney development-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:2000612-&&-regulation of thyroid-stimulating hormone secretion-%%-GO:0038194-&&-thyroid-stimulating hormone signaling pathway-%%-GO:0072307-&&-regulation of metanephric nephron tubule epithelial cell differentiation-%%-GO:0072305-&&-negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0003337-&&-mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1900215-&&-negative regulation of apoptotic process involved in metanephric collecting duct development-%%-GO:1900218-&&-negative regulation of apoptotic process involved in metanephric nephron tubule development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0072278-&&-metanephric comma-shaped body morphogenesis-%%-GO:0048793-&&-pronephros development-%%-GO:0071599-&&-otic vesicle development-%%-GO:2000594-&&-positive regulation of metanephric DCT cell differentiation-%%-GO:0072289-&&-metanephric nephron tubule formation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006790-&&-sulfur compound metabolic process-%%-GO:0072108-&&-positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0039003-&&-pronephric field specification-%%-GO:0072284-&&-metanephric S-shaped body morphogenesis-%%-GO:0072207-&&-metanephric epithelium development-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding-%%-GO:0004996-&&-thyroid-stimulating hormone receptor activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:PAX8			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05216-&&-Thyroid cancer	PAX8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAX8	0.35525579	0.14545455	11	5	FALSE	PAX8	PAX8	171.4545455	0	11	0	0.69752114	FALSE	0	PAX8	92036	0.13087295
788836	taxon:9606	3.02095478	1.03E-05	160392	1902	zinc activated ion channel	gene	biological_process-&-1&-GO:0098664-&&-G-protein coupled serotonin receptor signaling pathway-%%-GO:0007210-&&-serotonin receptor signaling pathway-%%-GO:0010043-&&-response to zinc ion-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004993-&&-G-protein coupled serotonin receptor activity-%%-GO:0005230-&&-extracellular ligand-gated ion channel activity-%%-GO:0015276-&&-ligand-gated ion channel activity	G:9606:ZACN				ZACN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZACN	0.33102117	0	11	4	FALSE	ZACN	ZACN	38.90909091	0	11	0	0.6631742	FALSE	0	ZACN	9900	0.10329453
788879	taxon:9606	2.87631952	5.25E-06	176701	1902	wolframin ER transmembrane glycoprotein	gene	biological_process-&-1&-GO:0022417-&&-protein maturation by protein folding-%%-GO:1903892-&&-negative regulation of ATF6-mediated unfolded protein response-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0050821-&&-protein stabilization-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0050877-&&-neurological system process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045927-&&-positive regulation of growth-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:2000675-&&-negative regulation of type B pancreatic cell apoptotic process-%%-GO:0045762-&&-positive regulation of adenylate cyclase activity-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0042048-&&-olfactory behavior-%%-GO:0007601-&&-visual perception-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0001822-&&-kidney development-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0031016-&&-pancreas development-%%-GO:0006983-&&-ER overload response-%%-GO:0043069-&&-negative regulation of programmed cell death|cellular_component-&-1&-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0000502-&&-proteasome complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0033613-&&-activating transcription factor binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:WFS1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	WFS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WFS1	0.34766652	0.05454545	11	4	FALSE	WFS1	WFS1	122.3636364	0	11	0	0.68728008	FALSE	0	WFS1	8808	0.11206824
788922	taxon:9606	2.8854577	1.03E-05	176588	1902	latent transforming growth factor beta binding protein 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007275-&&-multicellular organism development-%%-GO:0030162-&&-regulation of proteolysis-%%-GO:0030252-&&-growth hormone secretion-%%-GO:0045595-&&-regulation of cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005539-&&-glycosaminoglycan binding-%%-GO:0005024-&&-transforming growth factor beta-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005509-&&-calcium ion binding	G:9606:LTBP4				LTBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTBP4	0.34656547	0.01818182	11	4	FALSE	LTBP4	LTBP4	108	0	11	0	0.68575705	FALSE	0	LTBP4	11406	0.10633117
788930	taxon:9606	2.63778163	2.67E-05	176576	1902	glyceronephosphate O-acyltransferase	gene	biological_process-&-1&-GO:0070542-&&-response to fatty acid-%%-GO:0042594-&&-response to starvation-%%-GO:0061024-&&-membrane organization-%%-GO:0007584-&&-response to nutrient-%%-GO:0030913-&&-paranodal junction assembly-%%-GO:0007416-&&-synapse assembly-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0021587-&&-cerebellum morphogenesis-%%-GO:0042493-&&-response to drug-%%-GO:0008611-&&-ether lipid biosynthetic process|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016290-&&-palmitoyl-CoA hydrolase activity-%%-GO:0016287-&&-glycerone-phosphate O-acyltransferase activity-%%-GO:0005102-&&-receptor binding	G:9606:GNPAT			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04146-&&-Peroxisome	GNPAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNPAT	0.37910644	0.09090909	11	4	FALSE	GNPAT	GNPAT	296.4545455	0	11	0	0.7270364	FALSE	0	GNPAT	30764	0.12242825
789040	taxon:9606	2.71072948	5.57E-05	159924	1902	centromere protein S	gene	biological_process-&-1&-GO:0006312-&&-mitotic recombination-%%-GO:0031297-&&-replication fork processing-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0051382-&&-kinetochore assembly-%%-GO:0006281-&&-DNA repair-%%-GO:0051301-&&-cell division-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000712-&&-resolution of meiotic recombination intermediates-%%-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007062-&&-sister chromatid cohesion-%%-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0071821-&&-FANCM-MHF complex-%%-GO:0000777-&&-condensed chromosome kinetochore-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003682-&&-chromatin binding	G:9606:CENPS			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	CENPS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPS	0.36890439	0.36363636	11	4	FALSE	CENPS	CENPS	247.2727273	0	11	0	0.71487842	FALSE	0	CENPS	71110	0.12787471
789097	taxon:9606	2.93099102	5.38E-06	159813	1902	MAF bZIP transcription factor A	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0030073-&&-insulin secretion-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009749-&&-response to glucose|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:MAFA			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04950-&&-Maturity onset diabetes of the young	MAFA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAFA	0.34118153	0.12727273	11	5	FALSE	MAFA	MAFA	95.45454545	0	11	0	0.67816816	FALSE	0	MAFA	6338	0.12234167
789179	taxon:9606	2.68725382	3.48E-06	176041	1902	histone cluster 1 H2B family member m	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BM			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BM	0.37212711	0.2	11	4	FALSE	HIST1H2BM	HIST1H2BM	326.0909091	0	11	0	0.71879103	FALSE	0	HIST1H2BM	13072	0.156977
789230	taxon:9606	2.9700646	6.34E-06	175956	1902	transmembrane protein with EGF like and two follistatin like domains 1	gene	biological_process-&-1&-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:TMEFF1				TMEFF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEFF1	0.33669301	0.01818182	11	5	FALSE	TMEFF1	TMEFF1	62.45454545	0	11	0	0.6716559	FALSE	0	TMEFF1	7722	0.1199151
789243	taxon:9606	3.03261383	1.75E-05	175905	1902	aldo-keto reductase family 1 member C3	gene	biological_process-&-1&-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0044259-&&-multicellular organismal macromolecule metabolic process-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0044597-&&-daunorubicin metabolic process-%%-GO:2000224-&&-regulation of testosterone biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008584-&&-male gonad development-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0070293-&&-renal absorption-%%-GO:0071379-&&-cellular response to prostaglandin stimulus-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0071799-&&-cellular response to prostaglandin D stimulus-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0016488-&&-farnesol catabolic process-%%-GO:1900053-&&-negative regulation of retinoic acid biosynthetic process-%%-GO:0007584-&&-response to nutrient-%%-GO:0071384-&&-cellular response to corticosteroid stimulus-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0042572-&&-retinol metabolic process-%%-GO:0010942-&&-positive regulation of cell death-%%-GO:0042574-&&-retinal metabolic process-%%-GO:0006693-&&-prostaglandin metabolic process-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0071395-&&-cellular response to jasmonic acid stimulus-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0048385-&&-regulation of retinoic acid receptor signaling pathway-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0044598-&&-doxorubicin metabolic process-%%-GO:0061370-&&-testosterone biosynthetic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0047086-&&-ketosteroid monooxygenase activity-%%-GO:0035410-&&-dihydrotestosterone 17-beta-dehydrogenase activity-%%-GO:0047020-&&-15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity-%%-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0047115-&&-trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity-%%-GO:0047718-&&-indanol dehydrogenase activity-%%-GO:0047035-&&-testosterone dehydrogenase (NAD+) activity-%%-GO:0045703-&&-ketoreductase activity-%%-GO:0004745-&&-retinol dehydrogenase activity-%%-GO:0047023-&&-androsterone dehydrogenase activity-%%-GO:0047045-&&-testosterone 17-beta-dehydrogenase (NADP+) activity-%%-GO:0047787-&&-delta4-3-oxosteroid 5beta-reductase activity-%%-GO:0052650-&&-NADP-retinol dehydrogenase activity-%%-GO:0047017-&&-prostaglandin-F synthase activity-%%-GO:0036130-&&-prostaglandin H2 endoperoxidase reductase activity-%%-GO:0036131-&&-prostaglandin D2 11-ketoreductase activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0018636-&&-phenanthrene 9,10-monooxygenase activity-%%-GO:0045550-&&-geranylgeranyl reductase activity-%%-GO:0001758-&&-retinal dehydrogenase activity	G:9606:AKR1C3	AKR1C3	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis-%%-hsa00590-&&-Arachidonic acid metabolism	AKR1C3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1C3	0.32974855	0.05454545	11	5	FALSE	AKR1C3	AKR1C3	52.54545455	0	11	0	0.66123103	FALSE	0	AKR1C3	16502	0.11824394
789268	taxon:9606	2.85378919	2.35E-06	159483	1902	GTF2I repeat domain containing 2B	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:GTF2IRD2B				GTF2IRD2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2IRD2B	0.35041131	0.30555556	11	5	FALSE	GTF2IRD2B	GTF2IRD2B	167.2222222	0	10	0	0.69103513	FALSE	1	GTF2IRD2B	4460	0.14775518
789273	taxon:9606	2.9056247	1.85E-06	175845	1902	TNF receptor superfamily member 25	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006915-&&-apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005031-&&-tumor necrosis factor-activated receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:TNFRSF25			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF25	0.34416007	0.30555556	11	5	FALSE	TNFRSF25	TNFRSF25	126.6666667	0	10	0	0.68239588	FALSE	1	TNFRSF25	2962	0.14819152
789321	taxon:9606	3.08129825	2.76E-05	175740	1902	ADAM metallopeptidase with thrombospondin type 1 motif 1	gene	biological_process-&-1&-GO:0060347-&&-heart trabecula formation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0001822-&&-kidney development-%%-GO:0006508-&&-proteolysis-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0007229-&&-integrin-mediated signaling pathway|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:ADAMTS1				ADAMTS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAMTS1	0.32453853	0.01818182	11	5	FALSE	ADAMTS1	ADAMTS1	40.09090909	0	11	0	0.65311696	FALSE	0	ADAMTS1	22556	0.09602134
789432	taxon:9606	2.78178667	2.47E-05	175488	1902	slit guidance ligand 2	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0090260-&&-negative regulation of retinal ganglion cell axon guidance-%%-GO:0021836-&&-chemorepulsion involved in postnatal olfactory bulb interneuron migration-%%-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0071676-&&-negative regulation of mononuclear cell migration-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0090027-&&-negative regulation of monocyte chemotaxis-%%-GO:0048846-&&-axon extension involved in axon guidance-%%-GO:0061364-&&-apoptotic process involved in luteolysis-%%-GO:0071504-&&-cellular response to heparin-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0090288-&&-negative regulation of cellular response to growth factor stimulus-%%-GO:0021972-&&-corticospinal neuron axon guidance through spinal cord-%%-GO:0002689-&&-negative regulation of leukocyte chemotaxis-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:0051058-&&-negative regulation of small GTPase mediated signal transduction-%%-GO:0090024-&&-negative regulation of neutrophil chemotaxis-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0001657-&&-ureteric bud development-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0010596-&&-negative regulation of endothelial cell migration-%%-GO:0070100-&&-negative regulation of chemokine-mediated signaling pathway-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0010593-&&-negative regulation of lamellipodium assembly-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0071672-&&-negative regulation of smooth muscle cell chemotaxis-%%-GO:0051414-&&-response to cortisol-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0007411-&&-axon guidance-%%-GO:0021834-&&-chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration-%%-GO:0050929-&&-induction of negative chemotaxis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005095-&&-GTPase inhibitor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0048495-&&-Roundabout binding-%%-GO:0043394-&&-proteoglycan binding-%%-GO:0008201-&&-heparin binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043237-&&-laminin-1 binding	G:9606:SLIT2			KEGG-&-1&-hsa04360-&&-Axon guidance	SLIT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLIT2	0.3594812	0.13888889	11	4	FALSE	SLIT2	SLIT2	212.8888889	0	10	0	0.70303555	FALSE	1	SLIT2	20216	0.13983918
789514	taxon:9606	2.79265795	1.43E-05	175299	1902	regulating synaptic membrane exocytosis 2	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0048791-&&-calcium ion-regulated exocytosis of neurotransmitter-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:1903861-&&-positive regulation of dendrite extension-%%-GO:0017157-&&-regulation of exocytosis-%%-GO:0042391-&&-regulation of membrane potential-%%-GO:0097151-&&-positive regulation of inhibitory postsynaptic potential-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0061669-&&-spontaneous neurotransmitter secretion-%%-GO:0030073-&&-insulin secretion-%%-GO:0017156-&&-calcium ion regulated exocytosis|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005622-&&-intracellular-%%-GO:0048786-&&-presynaptic active zone|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:RIMS2			KEGG-&-1&-hsa04911-&&-Insulin secretion	RIMS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIMS2	0.35808181	0.09090909	11	4	FALSE	RIMS2	RIMS2	182.1818182	0	11	0	0.70122368	FALSE	0	RIMS2	16304	0.12602446
789538	taxon:9606	2.58956988	3.22E-06	175235	1902	dedicator of cytokinesis 4	gene	biological_process-&-1&-GO:1904754-&&-positive regulation of vascular associated smooth muscle cell migration-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:1904694-&&-negative regulation of vascular smooth muscle contraction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0032420-&&-stereocilium-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0032421-&&-stereocilium bundle|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0048365-&&-Rac GTPase binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0017124-&&-SH3 domain binding	G:9606:DOCK4			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway	DOCK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOCK4	0.38616452	0.32727273	11	4	FALSE	DOCK4	DOCK4	411.1818182	0	11	0	0.73507169	FALSE	0	DOCK4	10992	0.15371283
789640	taxon:9606	2.82338112	2.54E-06	174989	1902	Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2	gene	biological_process-&-1&-GO:1900164-&&-nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0022409-&&-positive regulation of cell-cell adhesion-%%-GO:0035802-&&-adrenal cortex formation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007507-&&-heart development-%%-GO:0035360-&&-positive regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0007530-&&-sex determination-%%-GO:0061428-&&-negative regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0001666-&&-response to hypoxia-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0003156-&&-regulation of animal organ formation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001889-&&-liver development-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0034405-&&-response to fluid shear stress-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:2000020-&&-positive regulation of male gonad development-%%-GO:0060971-&&-embryonic heart tube left/right pattern formation-%%-GO:0030511-&&-positive regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043627-&&-response to estrogen-%%-GO:0060972-&&-left/right pattern formation-%%-GO:0070986-&&-left/right axis specification-%%-GO:0008283-&&-cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0048536-&&-spleen development|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0050693-&&-LBD domain binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0035035-&&-histone acetyltransferase binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity	G:9606:CITED2			KEGG-&-1&-hsa04137-&&-Mitophagy - animal	CITED2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CITED2	0.35418527	0.45454545	11	4	FALSE	CITED2	CITED2	198.4545455	0	11	0	0.69610315	FALSE	0	CITED2	4524	0.15336518
789678	taxon:9606	2.77564204	4.11E-06	174915	1902	MER proto-oncogene, tyrosine kinase	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0097350-&&-neutrophil clearance-%%-GO:0050900-&&-leukocyte migration-%%-GO:0030168-&&-platelet activation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0006909-&&-phagocytosis-%%-GO:0043277-&&-apoptotic cell clearance-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0060068-&&-vagina development-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0032940-&&-secretion by cell-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0051250-&&-negative regulation of lymphocyte activation-%%-GO:2000107-&&-negative regulation of leukocyte apoptotic process-%%-GO:0001779-&&-natural killer cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016028-&&-rhabdomere-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MERTK				MERTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MERTK	0.36027701	0.19444444	11	5	FALSE	MERTK	MERTK	219.4444444	0	10	0	0.70405966	FALSE	1	MERTK	6394	0.1427228
789711	taxon:9606	2.96250197	1.55E-05	174844	1902	protein C receptor	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0050819-&&-negative regulation of coagulation-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:PROCR			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	PROCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PROCR	0.33755252	0.01818182	11	5	FALSE	PROCR	PROCR	63.09090909	0	11	0	0.67291634	FALSE	0	PROCR	12458	0.10396115
789726	taxon:9606	2.96092642	2.57E-06	174813	1902	BCL2 like 10	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007292-&&-female gamete generation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0089720-&&-caspase binding-%%-GO:0005515-&&-protein binding	G:9606:BCL2L10				BCL2L10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L10	0.33773213	0.41666667	11	4	FALSE	BCL2L10	BCL2L10	90.88888889	0	10	0	0.67317893	FALSE	1	BCL2L10	3554	0.15205658
789779	taxon:9606	2.81676383	5.77E-06	174698	1902	RNA binding motif protein 6	gene	biological_process-&-1&-GO:0006396-&&-RNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:RBM6				RBM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBM6	0.35501734	0.09090909	11	5	FALSE	RBM6	RBM6	173.9090909	0	11	0	0.69720603	FALSE	0	RBM6	9920	0.12587413
789827	taxon:9606	2.65243422	4.57E-06	174555	1902	TRAF-type zinc finger domain containing 1	gene	biological_process-&-1&-GO:0045824-&&-negative regulation of innate immune response|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:TRAFD1				TRAFD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAFD1	0.37701218	0.09090909	11	4	FALSE	TRAFD1	TRAFD1	321.0909091	0	11	0	0.7245943	FALSE	0	TRAFD1	9832	0.1413296
790000	taxon:9606	2.69008981	2.92E-06	174147	1902	FAST kinase domains 2	gene	biological_process-&-1&-GO:0045333-&&-cellular respiration-%%-GO:1902775-&&-mitochondrial large ribosomal subunit assembly-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0035770-&&-ribonucleoprotein granule-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0004672-&&-protein kinase activity	G:9606:FASTKD2				FASTKD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASTKD2	0.3717348	0.12727273	11	4	FALSE	FASTKD2	FASTKD2	290.1818182	0	11	0	0.71831837	FALSE	0	FASTKD2	9926	0.13940268
790019	taxon:9606	2.71624389	4.68E-06	157706	1902	coiled-coil domain containing 88C	gene	biological_process-&-1&-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0031648-&&-protein destabilization-%%-GO:0031098-&&-stress-activated protein kinase signaling cascade-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030705-&&-cytoskeleton-dependent intracellular transport-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0043621-&&-protein self-association-%%-GO:0008017-&&-microtubule binding-%%-GO:0051959-&&-dynein light intermediate chain binding-%%-GO:0030165-&&-PDZ domain binding	G:9606:CCDC88C				CCDC88C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC88C	0.36815545	0.12727273	11	4	FALSE	CCDC88C	CCDC88C	215.2727273	0	11	0	0.71395935	FALSE	0	CCDC88C	9234	0.11448349
790052	taxon:9606	2.91838664	6.77E-06	173999	1902	RCAN family member 3	gene	biological_process-&-1&-GO:0070884-&&-regulation of calcineurin-NFAT signaling cascade-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0009653-&&-anatomical structure morphogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008597-&&-calcium-dependent protein serine/threonine phosphatase regulator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0031013-&&-troponin I binding	G:9606:RCAN3				RCAN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCAN3	0.34265508	0.09090909	11	5	FALSE	RCAN3	RCAN3	83	0	11	0	0.68026889	FALSE	0	RCAN3	8106	0.10217416
790086	taxon:9606	2.77816291	3.34E-06	173915	1902	dual specificity phosphatase 10	gene	biological_process-&-1&-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0002819-&&-regulation of adaptive immune response-%%-GO:0016311-&&-dephosphorylation-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007254-&&-JNK cascade-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0043508-&&-negative regulation of JUN kinase activity-%%-GO:0060266-&&-negative regulation of respiratory burst involved in inflammatory response-%%-GO:0006950-&&-response to stress|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0016791-&&-phosphatase activity-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0033549-&&-MAP kinase phosphatase activity	G:9606:DUSP10			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP10	0.35995009	0.14545455	11	5	FALSE	DUSP10	DUSP10	189.7272727	0	11	0	0.70363951	FALSE	0	DUSP10	8012	0.12421065
790087	taxon:9606	2.84654167	3.97E-06	157530	1902	POTE ankyrin domain family member E	gene	biological_process-&-1&-GO:0001895-&&-retina homeostasis-%%-GO:0021762-&&-substantia nigra development|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:POTEE				POTEE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POTEE	0.35130348	0.09090909	11	4	FALSE	POTEE	POTEE	168.3636364	0	11	0	0.69224305	FALSE	0	POTEE	8676	0.14517144
790259	taxon:9606	2.76571609	6.50E-07	173489	1902	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	gene	biological_process-&-1&-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0046015-&&-regulation of transcription by glucose-%%-GO:0000183-&&-chromatin silencing at rDNA-%%-GO:0006364-&&-rRNA processing-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0032259-&&-methylation-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005677-&&-chromatin silencing complex-%%-GO:0033553-&&-rDNA heterochromatin|molecular_function-&-1&-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0035064-&&-methylated histone binding-%%-GO:0003723-&&-RNA binding	G:9606:RRP8				RRP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRP8	0.36157001	0.21818182	11	5	FALSE	RRP8	RRP8	282.2727273	0	11	0	0.70571399	FALSE	0	RRP8	3048	0.16957306
790289	taxon:9606	2.65432488	2.15E-05	173413	1902	ETHE1, persulfide dioxygenase	gene	biological_process-&-1&-GO:0070813-&&-hydrogen sulfide metabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0070221-&&-sulfide oxidation, using sulfide:quinone oxidoreductase|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0050313-&&-sulfur dioxygenase activity-%%-GO:0005506-&&-iron ion binding	G:9606:ETHE1			KEGG-&-1&-hsa00920-&&-Sulfur metabolism	ETHE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETHE1	0.37674363	0.05454545	11	4	FALSE	ETHE1	ETHE1	281.0909091	0	11	0	0.72427919	FALSE	0	ETHE1	29474	0.1233452
790347	taxon:9606	2.89191744	4.05E-06	173263	1902	RNA exonuclease 2	gene	biological_process-&-1&-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0009117-&&-nucleotide metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005925-&&-focal adhesion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005730-&&-nucleolus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0003676-&&-nucleic acid binding	G:9606:REXO2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes	REXO2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REXO2	0.34579134	0	11	4	FALSE	REXO2	REXO2	116	0	11	0	0.68468043	FALSE	0	REXO2	6742	0.12472885
790474	taxon:9606	2.87049	5.23E-06	172740	1902	WD repeat and SOCS box containing 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:WSB1				WSB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WSB1	0.34837258	0.21818182	11	5	FALSE	WSB1	WSB1	155.8181818	0	11	0	0.68825167	FALSE	0	WSB1	8722	0.13937765
790499	taxon:9606	2.9237435	3.01E-06	172686	1902	signal transducing adaptor family member 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1904140-&&-negative regulation of microglial cell migration-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:2000251-&&-positive regulation of actin cytoskeleton reorganization-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1903997-&&-positive regulation of non-membrane spanning protein tyrosine kinase activity-%%-GO:0060100-&&-positive regulation of phagocytosis, engulfment-%%-GO:1903980-&&-positive regulation of microglial cell activation-%%-GO:0010760-&&-negative regulation of macrophage chemotaxis-%%-GO:1900028-&&-negative regulation of ruffle assembly-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:1904151-&&-positive regulation of microglial cell mediated cytotoxicity-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:1902227-&&-negative regulation of macrophage colony-stimulating factor signaling pathway|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005068-&&-transmembrane receptor protein tyrosine kinase adaptor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005157-&&-macrophage colony-stimulating factor receptor binding-%%-GO:0005543-&&-phospholipid binding	G:9606:STAP1				STAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAP1	0.34202727	0.18181818	11	4	FALSE	STAP1	STAP1	100.6363636	0	11	0	0.67937608	FALSE	0	STAP1	4906	0.1322314
790517	taxon:9606	2.81471561	3.12E-06	172646	1902	sacsin molecular chaperone	gene	biological_process-&-1&-GO:0090084-&&-negative regulation of inclusion body assembly-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm-%%-GO:0070852-&&-cell body fiber-%%-GO:0030424-&&-axon-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0070628-&&-proteasome binding	G:9606:SACS				SACS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SACS	0.35527568	0.10909091	11	4	FALSE	SACS	SACS	159.5454546	0	11	0	0.6975474	FALSE	0	SACS	5850	0.11925855
790532	taxon:9606	2.75059083	6.72E-06	172568	1902	apurinic/apyrimidinic endodeoxyribonuclease 2	gene	biological_process-&-1&-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0006284-&&-base-excision repair-%%-GO:0006310-&&-DNA recombination-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0008311-&&-double-stranded DNA 3'-5' exodeoxyribonuclease activity	G:9606:APEX2			KEGG-&-1&-hsa03410-&&-Base excision repair	APEX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APEX2	0.36355825	0.05454545	11	5	FALSE	APEX2	APEX2	194.1818182	0	11	0	0.70823486	FALSE	0	APEX2	13260	0.11337024
790544	taxon:9606	2.7148259	5.65E-06	172532	1902	small G protein signaling modulator 3	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0032483-&&-regulation of Rab protein signal transduction-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0032486-&&-Rap protein signal transduction|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:SGSM3				SGSM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGSM3	0.36834775	0.12727273	11	4	FALSE	SGSM3	SGSM3	234.8181818	0	11	0	0.71419568	FALSE	0	SGSM3	12176	0.12054218
790559	taxon:9606	2.81849693	6.50E-06	172136	1902	neurobeachin	gene	biological_process-&-1&-GO:0008104-&&-protein localization|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0012505-&&-endomembrane system-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019901-&&-protein kinase binding	G:9606:NBEA				NBEA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBEA	0.35479904	0.07272727	11	4	FALSE	NBEA	NBEA	147.8181818	0	11	0	0.69691718	FALSE	0	NBEA	10370	0.1154695
790595	taxon:9606	2.68378762	2.33E-05	172019	1902	XIAP associated factor 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0035456-&&-response to interferon-beta|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:XAF1				XAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XAF1	0.37260773	0.16363636	11	4	FALSE	XAF1	XAF1	249.4545455	0	11	0	0.71936873	FALSE	0	XAF1	23012	0.1189412
790599	taxon:9606	3.0299354	5.38E-06	171995	1902	solute carrier family 39 member 1	gene	biological_process-&-1&-GO:0006812-&&-cation transport-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0060173-&&-limb development-%%-GO:0071577-&&-zinc II ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity-%%-GO:0022890-&&-inorganic cation transmembrane transporter activity-%%-GO:0005102-&&-receptor binding	G:9606:SLC39A1				SLC39A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A1	0.33004004	0.02777778	11	5	FALSE	SLC39A1	SLC39A1	45	0	10	0	0.66167743	FALSE	1	SLC39A1	4378	0.12148962
790604	taxon:9606	2.89254766	1.30E-05	171796	1902	ras homolog family member D	gene	biological_process-&-1&-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0048041-&&-focal adhesion assembly-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0006605-&&-protein targeting-%%-GO:2000249-&&-regulation of actin cytoskeleton reorganization-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0051017-&&-actin filament bundle assembly-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0003924-&&-GTPase activity	G:9606:RHOD			KEGG-&-1&-hsa04360-&&-Axon guidance	RHOD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOD	0.345716	0.16363636	11	4	FALSE	RHOD	RHOD	106	0	11	0	0.68457539	FALSE	0	RHOD	11736	0.12000826
790610	taxon:9606	2.66645659	2.21E-05	171766	1902	thioesterase superfamily member 6	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region	G:9606:THEM6				THEM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THEM6	0.37502954	0.10909091	11	4	FALSE	THEM6	THEM6	286.7272727	0	11	0	0.72225723	FALSE	0	THEM6	32124	0.1295177
790643	taxon:9606	3.03119584	3.48E-06	171687	1902	roundabout guidance receptor 4	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004872-&&-receptor activity	G:9606:ROBO4				ROBO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROBO4	0.3299028	0.11111111	11	5	FALSE	ROBO4	ROBO4	64.55555556	0	10	0	0.66146736	FALSE	1	ROBO4	3052	0.17293907
790652	taxon:9606	2.73483536	3.75E-06	171645	1902	Nedd4 family interacting protein 2	gene	biological_process-&-1&-GO:0032410-&&-negative regulation of transporter activity-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0007165-&&-signal transduction-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0051224-&&-negative regulation of protein transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0032585-&&-multivesicular body membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding	G:9606:NDFIP2				NDFIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDFIP2	0.36565272	0.2	11	4	FALSE	NDFIP2	NDFIP2	244.2727273	0	11	0	0.71086077	FALSE	0	NDFIP2	8692	0.13746479
790731	taxon:9606	2.97904522	4.19E-06	171363	1902	lactamase beta 2	gene	biological_process-&-1&-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:LACTB2				LACTB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LACTB2	0.33567802	0.09090909	11	4	FALSE	LACTB2	LACTB2	64.18181818	0	11	0	0.67015913	FALSE	0	LACTB2	4210	0.11022138
790738	taxon:9606	2.93225146	3.78E-06	171349	1902	N(alpha)-acetyltransferase 20, NatB catalytic subunit	gene	biological_process-&-1&-GO:0017196-&&-N-terminal peptidyl-methionine acetylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031416-&&-NatB complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004596-&&-peptide alpha-N-acetyltransferase activity	G:9606:NAA20				NAA20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAA20	0.34103487	0.08333333	11	5	FALSE	NAA20	NAA20	92.66666667	0	10	0	0.67795809	FALSE	1	NAA20	3696	0.12775466
790742	taxon:9606	2.83866394	2.99E-06	171341	1902	centrosomal protein 83	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0048278-&&-vesicle docking-%%-GO:0071539-&&-protein localization to centrosome-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0097539-&&-ciliary transition fiber|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:CEP83				CEP83	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP83	0.3522784	0.05555556	11	4	FALSE	CEP83	CEP83	163.4444444	0	10	0	0.69355601	FALSE	1	CEP83	5726	0.13596735
790811	taxon:9606	2.97053726	5.24E-06	171139	1902	CD209 molecule	gene	biological_process-&-1&-GO:0019079-&&-viral genome replication-%%-GO:0009988-&&-cell-cell recognition-%%-GO:0045087-&&-innate immune response-%%-GO:0075733-&&-intracellular transport of virus-%%-GO:0046968-&&-peptide antigen transport-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway-%%-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0042129-&&-regulation of T cell proliferation-%%-GO:0006897-&&-endocytosis-%%-GO:0019048-&&-modulation by virus of host morphology or physiology-%%-GO:0019062-&&-virion attachment to host cell-%%-GO:0035556-&&-intracellular signal transduction|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005537-&&-mannose binding-%%-GO:0005515-&&-protein binding-%%-GO:0042605-&&-peptide antigen binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0046790-&&-virion binding-%%-GO:0030246-&&-carbohydrate binding	G:9606:CD209			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04625-&&-C-type lectin receptor signaling pathway	CD209	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD209	0.33663944	0.05555556	11	4	FALSE	CD209	CD209	74.33333333	0	10	0	0.67157712	FALSE	1	CD209	4744	0.12380952
790930	taxon:9606	2.86781156	2.65E-06	170683	1902	Kruppel like factor 13	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045647-&&-negative regulation of erythrocyte differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:KLF13				KLF13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF13	0.34869795	0.18181818	11	4	FALSE	KLF13	KLF13	146.9090909	0	11	0	0.68869807	FALSE	0	KLF13	4546	0.1414044
790974	taxon:9606	2.88703324	4.73E-06	170541	1902	ecto-NOX disulfide-thiol exchanger 1	gene	biological_process-&-1&-GO:0048511-&&-rhythmic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005515-&&-protein binding	G:9606:ENOX1				ENOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENOX1	0.34637634	0.05454545	11	5	FALSE	ENOX1	ENOX1	133.9090909	0	11	0	0.68549446	FALSE	0	ENOX1	7510	0.13701833
790981	taxon:9606	2.62691035	2.58E-06	170517	1902	WD repeat domain 70	gene	molecular_function-&-1&-GO:0019899-&&-enzyme binding	G:9606:WDR70				WDR70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR70	0.38067534	0.21818182	11	4	FALSE	WDR70	WDR70	319.4545455	0	11	0	0.72884827	FALSE	0	WDR70	7058	0.12893163
791012	taxon:9606	2.70489995	9.97E-06	170389	1902	DnaJ heat shock protein family (Hsp40) member B12	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane	G:9606:DNAJB12			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJB12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJB12	0.36969944	0.29090909	11	4	FALSE	DNAJB12	DNAJB12	240.5454546	0	11	0	0.71585001	FALSE	0	DNAJB12	16910	0.12421893
791039	taxon:9606	2.85961872	7.47E-06	170272	1902	transmembrane protein 161A	gene	biological_process-&-1&-GO:0034644-&&-cellular response to UV-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:1902230-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0034599-&&-cellular response to oxidative stress|cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMEM161A				TMEM161A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM161A	0.34969697	0.03636364	11	4	FALSE	TMEM161A	TMEM161A	122.3636364	0	11	0	0.69006355	FALSE	0	TMEM161A	10840	0.11098208
791068	taxon:9606	2.88797857	3.63E-06	170153	1902	ring finger protein 220	gene	biological_process-&-1&-GO:0051865-&&-protein autoubiquitination-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:RNF220				RNF220	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF220	0.34626296	0.07272727	11	5	FALSE	RNF220	RNF220	133.6363636	0	11	0	0.6853369	FALSE	0	RNF220	6046	0.13753635
791071	taxon:9606	2.83992437	1.27E-05	170148	1902	RIC8 guanine nucleotide exchange factor B	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005938-&&-cell cortex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0001965-&&-G-protein alpha-subunit binding	G:9606:RIC8B				RIC8B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIC8B	0.35212205	0.01818182	11	4	FALSE	RIC8B	RIC8B	123.2727273	0	11	0	0.69334594	FALSE	0	RIC8B	17124	0.10359945
791084	taxon:9606	2.71718922	6.44E-06	170112	1902	leucine rich repeat containing 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane	G:9606:LRRC1				LRRC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRC1	0.36802737	0.2	11	5	FALSE	LRRC1	LRRC1	223	0	11	0	0.7138018	FALSE	0	LRRC1	12780	0.11764424
791085	taxon:9606	2.84228769	5.82E-06	170108	1902	coiled-coil domain containing 87	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC87				CCDC87	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC87	0.35182927	0.16363636	11	5	FALSE	CCDC87	CCDC87	154.1818182	0	11	0	0.69295205	FALSE	0	CCDC87	8474	0.129914
791117	taxon:9606	2.78493777	1.65E-05	169998	1902	phosphatidylinositol 4-kinase type 2 alpha	gene	biological_process-&-1&-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0007030-&&-Golgi organization-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0007032-&&-endosome organization|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0030054-&&-cell junction-%%-GO:0044231-&&-host cell presynaptic membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0031224-&&-intrinsic component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031083-&&-BLOC-1 complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005739-&&-mitochondrion-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0030425-&&-dendrite-%%-GO:0016020-&&-membrane-%%-GO:0035838-&&-growing cell tip|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004430-&&-1-phosphatidylinositol 4-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0035651-&&-AP-3 adaptor complex binding	G:9606:PI4K2A			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PI4K2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PI4K2A	0.35907445	0.07272727	11	5	FALSE	PI4K2A	PI4K2A	159.5454546	0	11	0	0.70251037	FALSE	0	PI4K2A	12542	0.10529801
791139	taxon:9606	2.77800536	4.60E-06	169910	1902	tripartite motif containing 36	gene	biological_process-&-1&-GO:0007340-&&-acrosome reaction-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001669-&&-acrosomal vesicle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:TRIM36				TRIM36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM36	0.35997051	0.05555556	11	4	FALSE	TRIM36	TRIM36	218.1111111	0	10	0	0.70366577	FALSE	1	TRIM36	9316	0.13974579
791165	taxon:9606	2.69875532	8.16E-06	169840	1902	phosphofurin acidic cluster sorting protein 1	gene	biological_process-&-1&-GO:0000042-&&-protein targeting to Golgi-%%-GO:0050690-&&-regulation of defense response to virus by virus-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0030137-&&-COPI-coated vesicle-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding	G:9606:PACS1				PACS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PACS1	0.37054119	0.2	11	4	FALSE	PACS1	PACS1	234.1818182	0	11	0	0.71687411	FALSE	0	PACS1	12194	0.11646314
791196	taxon:9606	2.87521664	1.44E-06	169767	1902	tyrosyl-DNA phosphodiesterase 1	gene	biological_process-&-1&-GO:0006302-&&-double-strand break repair-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0000012-&&-single strand break repair-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0017005-&&-3'-tyrosyl-DNA phosphodiesterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004527-&&-exonuclease activity	G:9606:TDP1				TDP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TDP1	0.34779988	0.30555556	11	4	FALSE	TDP1	TDP1	143.4444444	0	10	0	0.68746389	FALSE	1	TDP1	2978	0.14566396
791317	taxon:9606	2.90688514	1.66E-05	169203	1902	aldo-keto reductase family 1 member B10	gene	biological_process-&-1&-GO:0007586-&&-digestion-%%-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0016488-&&-farnesol catabolic process-%%-GO:0044598-&&-doxorubicin metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0047718-&&-indanol dehydrogenase activity-%%-GO:0005515-&&-protein binding-%%-GO:0045550-&&-geranylgeranyl reductase activity-%%-GO:0001758-&&-retinal dehydrogenase activity	G:9606:AKR1B10			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	AKR1B10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1B10	0.34401084	0.05454545	11	4	FALSE	AKR1B10	AKR1B10	94.36363636	0	11	0	0.68218581	FALSE	0	AKR1B10	17196	0.10697626
791343	taxon:9606	2.70143375	9.84E-06	169079	1902	ARFGEF family member 3	gene	biological_process-&-1&-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030658-&&-transport vesicle membrane|molecular_function-&-1&-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity	G:9606:ARFGEF3				ARFGEF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARFGEF3	0.3701738	0.10909091	11	5	FALSE	ARFGEF3	ARFGEF3	272.3636364	0	11	0	0.71642771	FALSE	0	ARFGEF3	16918	0.13550258
791378	taxon:9606	2.74885773	2.96E-06	168891	1902	cyclin B1 interacting protein 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0007131-&&-reciprocal meiotic recombination-%%-GO:0051026-&&-chiasma assembly-%%-GO:0001825-&&-blastocyst formation-%%-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0000795-&&-synaptonemal complex|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:CCNB1IP1				CCNB1IP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNB1IP1	0.36378747	0.11111111	11	4	FALSE	CCNB1IP1	CCNB1IP1	228.5555556	0	10	0	0.70852371	FALSE	1	CCNB1IP1	7390	0.13497699
791388	taxon:9606	2.80557744	4.50E-06	168837	1902	SR-related CTD associated factor 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008380-&&-RNA splicing-%%-GO:0006397-&&-mRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:SCAF1				SCAF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAF1	0.35643286	0.12727273	11	4	FALSE	SCAF1	SCAF1	200.6363636	0	11	0	0.69907043	FALSE	0	SCAF1	9302	0.13988946
791401	taxon:9606	2.87584686	6.40E-06	168776	1902	PC-esterase domain containing 1A	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PCED1A				PCED1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCED1A	0.34772366	0.27272727	11	5	FALSE	PCED1A	PCED1A	137.8181818	0	11	0	0.68735886	FALSE	0	PCED1A	13752	0.13179643
791407	taxon:9606	2.67386167	3.91E-06	168767	1902	CREB regulated transcription coactivator 3	gene	biological_process-&-1&-GO:0042116-&&-macrophage activation-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043951-&&-negative regulation of cAMP-mediated signaling-%%-GO:0097009-&&-energy homeostasis-%%-GO:0016032-&&-viral process-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008140-&&-cAMP response element binding protein binding	G:9606:CRTC3			KEGG-&-1&-hsa05166-&&-Human T-cell leukemia virus 1 infection	CRTC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRTC3	0.37399093	0.27272727	11	4	FALSE	CRTC3	CRTC3	297.8181818	0	11	0	0.72102306	FALSE	0	CRTC3	7846	0.13764553
791474	taxon:9606	2.85804317	8.55E-06	168490	1902	ectodysplasin A2 receptor	gene	biological_process-&-1&-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0009888-&&-tissue development-%%-GO:0010668-&&-ectodermal cell differentiation-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0008544-&&-epidermis development-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity	G:9606:EDA2R			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	EDA2R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EDA2R	0.34988975	0.18181818	11	4	FALSE	EDA2R	EDA2R	133.5454546	0	11	0	0.69032614	FALSE	0	EDA2R	9710	0.12255148
791496	taxon:9606	2.88829368	8.42E-06	168382	1902	DnaJ heat shock protein family (Hsp40) member C1	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0006417-&&-regulation of translation-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0045861-&&-negative regulation of proteolysis|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:DNAJC1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	DNAJC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC1	0.34622518	0.03636364	11	4	FALSE	DNAJC1	DNAJC1	119.1818182	0	11	0	0.68528439	FALSE	0	DNAJC1	9850	0.13142512
791518	taxon:9606	2.75972901	1.44E-05	168299	1902	testis specific protein, Y-linked 2	gene	biological_process-&-1&-GO:0007506-&&-gonadal mesoderm development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:TSPY2				TSPY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPY2	0.36235442	0.55555556	11	5	FALSE	TSPY2	TSPY2	228.3333333	0	10	0	0.70671183	FALSE	1	TSPY2	9456	0.14059934
791549	taxon:9606	2.89002678	1.77E-06	151721	1902	forkhead box O6	gene	biological_process-&-1&-GO:0060999-&&-positive regulation of dendritic spine development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:FOXO6			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway	FOXO6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXO6	0.34601755	0.4	11	4	FALSE	FOXO6	FOXO6	118	0	11	0	0.68499554	FALSE	0	FOXO6	2750	0.11967546
791779	taxon:9606	2.68142429	9.96E-06	166929	1902	fatty acyl-CoA reductase 1	gene	biological_process-&-1&-GO:0046474-&&-glycerophospholipid biosynthetic process-%%-GO:0010025-&&-wax biosynthetic process-%%-GO:0035336-&&-long-chain fatty-acyl-CoA metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008611-&&-ether lipid biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005777-&&-peroxisome-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0050062-&&-long-chain-fatty-acyl-CoA reductase activity-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0080019-&&-fatty-acyl-CoA reductase (alcohol-forming) activity	G:9606:FAR1			KEGG-&-1&-hsa04146-&&-Peroxisome	FAR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAR1	0.37293613	0.03636364	11	4	FALSE	FAR1	FAR1	295.9090909	0	11	0	0.71976262	FALSE	0	FAR1	24110	0.13817161
791815	taxon:9606	2.92327084	5.65E-06	166738	1902	ubiquitin specific peptidase 38	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|molecular_function-&-1&-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity	G:9606:USP38				USP38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP38	0.34208257	0.03636364	11	5	FALSE	USP38	USP38	95.18181818	0	11	0	0.67945486	FALSE	0	USP38	6066	0.11759385
791825	taxon:9606	2.74161021	8.21E-06	166678	1902	splA/ryanodine receptor domain and SOCS box containing 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:SPSB2				SPSB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPSB2	0.36474915	0.12727273	11	5	FALSE	SPSB2	SPSB2	197.8181818	0	11	0	0.70973163	FALSE	0	SPSB2	20258	0.11481305
791835	taxon:9606	2.72427919	9.58E-05	166613	1902	protein tyrosine phosphatase, non-receptor type 5	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0001784-&&-phosphotyrosine binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PTPN5			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PTPN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN5	0.36706957	0.07272727	11	4	FALSE	PTPN5	PTPN5	230.7272727	0	11	0	0.71262014	FALSE	0	PTPN5	109180	0.12710205
791870	taxon:9606	3.26626753	1.18E-05	166569	1902	ALG10, alpha-1,2-glucosyltransferase	gene	biological_process-&-1&-GO:0006486-&&-protein glycosylation-%%-GO:0006488-&&-dolichol-linked oligosaccharide biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004583-&&-dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity	G:9606:ALG10			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways	ALG10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALG10	0.30615986	0	11	5	FALSE	ALG10	ALG10	20.18181818	0	11	0	0.62228875	FALSE	0	ALG10	6654	0.10961039
791884	taxon:9606	2.6866236	1.03E-05	166543	1902	tensin 4	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008104-&&-protein localization|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding	G:9606:TNS4				TNS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNS4	0.3722144	0.30909091	11	4	FALSE	TNS4	TNS4	277.8181818	0	11	0	0.71889607	FALSE	0	TNS4	13070	0.13392975
791935	taxon:9606	2.96124153	1.18E-05	182845	1902	alkaline phosphatase, intestinal	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation-%%-GO:0007586-&&-digestion-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0006654-&&-phosphatidic acid biosynthetic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004035-&&-alkaline phosphatase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ALPI			KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00790-&&-Folate biosynthesis	ALPI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALPI	0.3376962	0.34545455	11	5	FALSE	ALPI	ALPI	100.2727273	0	11	0	0.67312641	FALSE	0	ALPI	14280	0.15422328
791951	taxon:9606	2.77579959	1.55E-05	182812	1902	ankyrin 1	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006887-&&-exocytosis-%%-GO:0007165-&&-signal transduction-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0045199-&&-maintenance of epithelial cell apical/basal polarity-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0010638-&&-positive regulation of organelle organization|cellular_component-&-1&-GO:0031430-&&-M band-%%-GO:0005886-&&-plasma membrane-%%-GO:0014731-&&-spectrin-associated cytoskeleton-%%-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030673-&&-axolemma-%%-GO:0030018-&&-Z disc-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0030507-&&-spectrin binding-%%-GO:0008093-&&-cytoskeletal adaptor activity-%%-GO:0005198-&&-structural molecule activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0051117-&&-ATPase binding	G:9606:ANK1			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	ANK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANK1	0.36025656	0.2	11	4	FALSE	ANK1	ANK1	177.1818182	0	11	0	0.7040334	FALSE	0	ANK1	13130	0.11351981
791965	taxon:9606	2.82007248	9.73E-06	182799	1902	annexin A3	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006909-&&-phagocytosis-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0070848-&&-response to growth factor-%%-GO:0051054-&&-positive regulation of DNA metabolic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0030424-&&-axon-%%-GO:0042581-&&-specific granule-%%-GO:0016020-&&-membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0019834-&&-phospholipase A2 inhibitor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0048306-&&-calcium-dependent protein binding	G:9606:ANXA3				ANXA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANXA3	0.35460082	0.05454545	11	4	FALSE	ANXA3	ANXA3	147.0909091	0	11	0	0.69665459	FALSE	0	ANXA3	13908	0.11053173
792022	taxon:9606	2.78336222	8.71E-06	182723	1902	BCL2 interacting killer	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008584-&&-male gonad development-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0007283-&&-spermatogenesis-%%-GO:0032464-&&-positive regulation of protein homooligomerization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0051400-&&-BH domain binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding	G:9606:BIK			KEGG-&-1&-hsa01522-&&-Endocrine resistance	BIK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BIK	0.35927771	0.16363636	11	4	FALSE	BIK	BIK	170.0909091	0	11	0	0.70277296	FALSE	0	BIK	13784	0.11054593
792105	taxon:9606	2.73672601	3.05E-05	182600	1902	collagen type IV alpha 3 chain	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032836-&&-glomerular basement membrane development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0038063-&&-collagen-activated tyrosine kinase receptor signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0008015-&&-blood circulation-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0072577-&&-endothelial cell apoptotic process|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005587-&&-collagen type IV trimer-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL4A3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer	COL4A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A3	0.36540012	0.12727273	11	4	FALSE	COL4A3	COL4A3	204.3636364	0	11	0	0.71054566	FALSE	0	COL4A3	35820	0.11472226
792124	taxon:9606	2.75642036	6.82E-06	166173	1902	OTU deubiquitinase with linear linkage specificity	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0070431-&&-nucleotide-binding oligomerization domain containing 2 signaling pathway-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:1990108-&&-protein linear deubiquitination-%%-GO:0050728-&&-negative regulation of inflammatory response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0071797-&&-LUBAC complex|molecular_function-&-1&-GO:0008234-&&-cysteine-type peptidase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity-%%-GO:0005515-&&-protein binding	G:9606:OTULIN				OTULIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTULIN	0.36278937	0.25454545	11	4	FALSE	OTULIN	OTULIN	207.2727273	0	11	0	0.70726327	FALSE	0	OTULIN	12486	0.1242497
792428	taxon:9606	3.04175201	1.22E-05	182037	1902	cystatin C	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0009743-&&-response to carbohydrate-%%-GO:0060548-&&-negative regulation of cell death-%%-GO:0006915-&&-apoptotic process-%%-GO:0007431-&&-salivary gland development-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0006952-&&-defense response-%%-GO:0042747-&&-circadian sleep/wake cycle, REM sleep-%%-GO:0060311-&&-negative regulation of elastin catabolic process-%%-GO:0010716-&&-negative regulation of extracellular matrix disassembly-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0007566-&&-embryo implantation-%%-GO:0010711-&&-negative regulation of collagen catabolic process-%%-GO:0045861-&&-negative regulation of proteolysis-%%-GO:0060009-&&-Sertoli cell development-%%-GO:0048678-&&-response to axon injury-%%-GO:0042493-&&-response to drug-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043067-&&-regulation of programmed cell death-%%-GO:0007420-&&-brain development-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0034103-&&-regulation of tissue remodeling-%%-GO:0060313-&&-negative regulation of blood vessel remodeling-%%-GO:0009636-&&-response to toxic substance-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001654-&&-eye development-%%-GO:0032355-&&-response to estradiol|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005771-&&-multivesicular body-%%-GO:0005764-&&-lysosome-%%-GO:0005576-&&-extracellular region-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005604-&&-basement membrane-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0030424-&&-axon-%%-GO:0043292-&&-contractile fiber-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0005515-&&-protein binding-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity	G:9606:CST3			KEGG-&-1&-hsa04970-&&-Salivary secretion	CST3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CST3	0.3287579	0.13888889	11	4	FALSE	CST3	CST3	54.66666667	0	10	0	0.659708	FALSE	1	CST3	11474	0.12609819
792442	taxon:9606	2.58153458	8.15E-06	182014	1902	catenin alpha 2	gene	biological_process-&-1&-GO:0048813-&&-dendrite morphogenesis-%%-GO:0060134-&&-prepulse inhibition-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0048854-&&-brain morphogenesis-%%-GO:0051823-&&-regulation of synapse structural plasticity-%%-GO:0021942-&&-radial glia guided migration of Purkinje cell-%%-GO:0007409-&&-axonogenesis-%%-GO:0051149-&&-positive regulation of muscle cell differentiation|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005912-&&-adherens junction-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0014069-&&-postsynaptic density-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0051015-&&-actin filament binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005515-&&-protein binding-%%-GO:0045296-&&-cadherin binding	G:9606:CTNNA2			KEGG-&-1&-hsa04390-&&-Hippo signaling pathway-%%-hsa05213-&&-Endometrial cancer-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa05200-&&-Pathways in cancer-%%-hsa04520-&&-Adherens junction-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05226-&&-Gastric cancer	CTNNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTNNA2	0.38736649	0.30909091	11	4	FALSE	CTNNA2	CTNNA2	411.2727273	0	11	0	0.7364109	FALSE	0	CTNNA2	13184	0.15124758
792458	taxon:9606	2.9202773	3.20E-06	181981	1902	cytochrome b-245 beta chain	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0006811-&&-ion transport-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0045087-&&-innate immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045730-&&-respiratory burst-%%-GO:1990776-&&-response to angiotensin-%%-GO:0050665-&&-hydrogen peroxide biosynthetic process-%%-GO:0007584-&&-response to nutrient-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0097411-&&-hypoxia-inducible factor-1alpha signaling pathway-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0042493-&&-response to drug-%%-GO:0042554-&&-superoxide anion generation-%%-GO:1904044-&&-response to aldosterone-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:1904845-&&-cellular response to L-glutamine-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005635-&&-nuclear envelope-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0043020-&&-NADPH oxidase complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CYBB			KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04145-&&-Phagosome-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05140-&&-Leishmaniasis-%%-hsa04217-&&-Necroptosis-%%-hsa04216-&&-Ferroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	CYBB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYBB	0.34243323	0.50909091	11	4	FALSE	CYBB	CYBB	102.7272727	0	11	0	0.67995378	FALSE	0	CYBB	4944	0.13570313
792468	taxon:9606	2.7861982	6.89E-06	181974	1902	arginine vasopressin receptor 2	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0035811-&&-negative regulation of urine volume-%%-GO:0034097-&&-response to cytokine-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0061024-&&-membrane organization-%%-GO:0001992-&&-regulation of systemic arterial blood pressure by vasopressin-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0032609-&&-interferon-gamma production-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0021537-&&-telencephalon development-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1901652-&&-response to peptide-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0035814-&&-negative regulation of renal sodium excretion-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007599-&&-hemostasis-%%-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007588-&&-excretion-%%-GO:0003084-&&-positive regulation of systemic arterial blood pressure|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0005000-&&-vasopressin receptor activity	G:9606:AVPR2			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	AVPR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AVPR2	0.35891201	0.2	11	4	FALSE	AVPR2	AVPR2	181.7272727	0	11	0	0.7023003	FALSE	0	AVPR2	10304	0.12339427
792481	taxon:9606	2.8374035	3.21E-05	181951	1902	branched chain amino acid transaminase 2	gene	biological_process-&-1&-GO:0009099-&&-valine biosynthetic process-%%-GO:0010817-&&-regulation of hormone levels-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0006550-&&-isoleucine catabolic process-%%-GO:0009082-&&-branched-chain amino acid biosynthetic process-%%-GO:0009098-&&-leucine biosynthetic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004084-&&-branched-chain-amino-acid transaminase activity-%%-GO:0052654-&&-L-leucine transaminase activity-%%-GO:0052655-&&-L-valine transaminase activity-%%-GO:0052656-&&-L-isoleucine transaminase activity	G:9606:BCAT2			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00770-&&-Pantothenate and CoA biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00290-&&-Valine, leucine and isoleucine biosynthesis	BCAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAT2	0.35243489	0.05555556	11	4	FALSE	BCAT2	BCAT2	155.4444444	0	10	0	0.69376608	FALSE	1	BCAT2	19620	0.12168064
792489	taxon:9606	2.8972743	1.32E-05	181943	1902	serpin family G member 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0045087-&&-innate immune response-%%-GO:0001869-&&-negative regulation of complement activation, lectin pathway-%%-GO:0007568-&&-aging-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0042730-&&-fibrinolysis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0008015-&&-blood circulation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:SERPING1			KEGG-&-1&-hsa05133-&&-Pertussis-%%-hsa04610-&&-Complement and coagulation cascades	SERPING1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPING1	0.34515199	0.07272727	11	4	FALSE	SERPING1	SERPING1	93	0	11	0	0.68378762	FALSE	0	SERPING1	12378	0.10626959
792548	taxon:9606	2.86639357	8.78E-06	181824	1902	calcium sensing receptor	gene	biological_process-&-1&-GO:0005513-&&-detection of calcium ion-%%-GO:0070509-&&-calcium ion import-%%-GO:0007635-&&-chemosensory behavior-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0001503-&&-ossification|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity	G:9606:CASR	CASR	TRUE	KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04621-&&-NOD-like receptor signaling pathway	CASR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASR	0.34887044	0.05555556	11	4	FALSE	CASR	CASR	139.6666667	0	10	0	0.6889344	FALSE	1	CASR	7496	0.14023297
792552	taxon:9606	2.77942335	2.81E-05	181820	1902	caveolin 2	gene	biological_process-&-1&-GO:0016050-&&-vesicle organization-%%-GO:0070836-&&-caveola assembly-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0044794-&&-positive regulation by host of viral process-%%-GO:0048278-&&-vesicle docking-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0006906-&&-vesicle fusion-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0051259-&&-protein oligomerization-%%-GO:0044791-&&-positive regulation by host of viral release from host cell-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0060161-&&-positive regulation of dopamine receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0019065-&&-receptor-mediated endocytosis of virus by host cell-%%-GO:0007005-&&-mitochondrion organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030133-&&-transport vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0005901-&&-caveola-%%-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005515-&&-protein binding-%%-GO:0032947-&&-protein complex scaffold-%%-GO:0097110-&&-scaffold protein binding	G:9606:CAV2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells	CAV2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAV2	0.35978686	0.32727273	11	5	FALSE	CAV2	CAV2	183.4545455	0	11	0	0.70342944	FALSE	0	CAV2	22946	0.12069378
792602	taxon:9606	2.7809989	7.18E-06	181732	1902	dual specificity phosphatase 9	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007254-&&-JNK cascade|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:DUSP9			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	DUSP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP9	0.35958303	0.21818182	11	4	FALSE	DUSP9	DUSP9	189.3636364	0	11	0	0.70316685	FALSE	0	DUSP9	10974	0.1256791
792658	taxon:9606	2.92327084	1.28E-05	181621	1902	cytochrome P450 family 2 subfamily E member 1	gene	biological_process-&-1&-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0042197-&&-halogenated hydrocarbon metabolic process-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0010193-&&-response to ozone-%%-GO:0017144-&&-drug metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0018910-&&-benzene metabolic process-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0018885-&&-carbon tetrachloride metabolic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0006641-&&-triglyceride metabolic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0031227-&&-intrinsic component of endoplasmic reticulum membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0008392-&&-arachidonic acid epoxygenase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0016709-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen-%%-GO:0016712-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-%%-GO:0020037-&&-heme binding	G:9606:CYP2E1			KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CYP2E1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP2E1	0.34208257	0.01818182	11	4	FALSE	CYP2E1	CYP2E1	71.81818182	0	11	0	0.67945486	FALSE	0	CYP2E1	11808	0.10289855
792742	taxon:9606	2.98708051	1.87E-06	181456	1902	Fc fragment of IgG receptor Ia	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0050776-&&-regulation of immune response-%%-GO:0007165-&&-signal transduction-%%-GO:0006955-&&-immune response-%%-GO:0002479-&&-antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0005515-&&-protein binding-%%-GO:0019864-&&-IgG binding	G:9606:FCGR1A			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05150-&&-Staphylococcus aureus infection	FCGR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCGR1A	0.33477504	0.44444444	11	5	FALSE	FCGR1A	FCGR1A	95.77777778	0	10	0	0.66881991	FALSE	1	FCGR1A	2080	0.17902388
792747	taxon:9606	3.17015913	1.59E-05	181447	1902	ficolin 1	gene	biological_process-&-1&-GO:0034394-&&-protein localization to cell surface-%%-GO:0006956-&&-complement activation-%%-GO:0006508-&&-proteolysis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0002752-&&-cell surface pattern recognition receptor signaling pathway-%%-GO:0043654-&&-recognition of apoptotic cell-%%-GO:0001867-&&-complement activation, lectin pathway-%%-GO:2000484-&&-positive regulation of interleukin-8 secretion-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005581-&&-collagen trimer-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0031232-&&-extrinsic component of external side of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008329-&&-signaling pattern recognition receptor activity-%%-GO:0030246-&&-carbohydrate binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0033691-&&-sialic acid binding-%%-GO:0005515-&&-protein binding	G:9606:FCN1				FCN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCN1	0.31544158	0	11	5	FALSE	FCN1	FCN1	23.22222222	0	10	0	0.63830681	FALSE	1	FCN1	9678	0.11820331
792762	taxon:9606	3.06286435	9.82E-06	181419	1902	fibroblast growth factor 7	gene	biological_process-&-1&-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0009611-&&-response to wounding-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0061033-&&-secretion by lung epithelial cell involved in lung growth-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0060501-&&-positive regulation of epithelial cell proliferation involved in lung morphogenesis-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis-%%-GO:0010463-&&-mesenchymal cell proliferation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0060665-&&-regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling-%%-GO:0008544-&&-epidermis development-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0051549-&&-positive regulation of keratinocyte migration|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0005104-&&-fibroblast growth factor receptor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0008201-&&-heparin binding-%%-GO:0008083-&&-growth factor activity	G:9606:FGF7			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer	FGF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGF7	0.32649177	0.03636364	11	5	FALSE	FGF7	FGF7	41	0	11	0	0.65618928	FALSE	0	FGF7	6460	0.11402157
792806	taxon:9606	2.87474397	7.68E-06	164956	1902	nuclear receptor coactivator 7	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0035257-&&-nuclear hormone receptor binding-%%-GO:0005515-&&-protein binding	G:9606:NCOA7				NCOA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCOA7	0.34785706	0.2	11	5	FALSE	NCOA7	NCOA7	126.4545455	0	11	0	0.68754267	FALSE	0	NCOA7	9034	0.12200264
792826	taxon:9606	2.9484796	1.39E-05	181297	1902	erythrocyte membrane protein band 4.2	gene	biological_process-&-1&-GO:0018149-&&-peptide cross-linking-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0020027-&&-hemoglobin metabolic process-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:0048536-&&-spleen development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005856-&&-cytoskeleton-%%-GO:0030863-&&-cortical cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0003810-&&-protein-glutamine gamma-glutamyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:EPB42				EPB42	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPB42	0.33915785	0.07272727	11	4	FALSE	EPB42	EPB42	72.18181818	0	11	0	0.6752534	FALSE	0	EPB42	10144	0.11023953
793008	taxon:9606	2.66897747	1.58E-05	180930	1902	fyn related Src family tyrosine kinase	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030154-&&-cell differentiation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:FRK				FRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FRK	0.37467532	0.25454545	11	4	FALSE	FRK	FRK	271.0909091	0	11	0	0.72183709	FALSE	0	FRK	15076	0.12488479
793039	taxon:9606	2.65101623	6.22E-06	180854	1902	Rho GTPase activating protein 35	gene	biological_process-&-1&-GO:0007413-&&-axonal fasciculation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030879-&&-mammary gland development-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0016477-&&-cell migration-%%-GO:0031668-&&-cellular response to extracellular stimulus-%%-GO:0043116-&&-negative regulation of vascular permeability-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008064-&&-regulation of actin polymerization or depolymerization-%%-GO:0043010-&&-camera-type eye development-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0021955-&&-central nervous system neuron axonogenesis-%%-GO:0001843-&&-neural tube closure-%%-GO:0030900-&&-forebrain development-%%-GO:0030950-&&-establishment or maintenance of actin cytoskeleton polarity-%%-GO:0007411-&&-axon guidance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045724-&&-positive regulation of cilium assembly-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:0097485-&&-neuron projection guidance-%%-GO:0035024-&&-negative regulation of Rho protein signal transduction-%%-GO:0044319-&&-wound healing, spreading of cells|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003714-&&-transcription corepressor activity-%%-GO:0005525-&&-GTP binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005543-&&-phospholipid binding	G:9606:ARHGAP35			KEGG-&-1&-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa04510-&&-Focal adhesion-%%-hsa04611-&&-Platelet activation-%%-hsa04810-&&-Regulation of actin cytoskeleton	ARHGAP35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP35	0.37721384	0.16363636	11	4	FALSE	ARHGAP35	ARHGAP35	288.2727273	0	11	0	0.72483063	FALSE	0	ARHGAP35	11164	0.12530178
793064	taxon:9606	2.81361273	1.20E-05	180815	1902	glutathione S-transferase zeta 1	gene	biological_process-&-1&-GO:0006572-&&-tyrosine catabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0006559-&&-L-phenylalanine catabolic process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0016034-&&-maleylacetoacetate isomerase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:GSTZ1			KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa01100-&&-Metabolic pathways	GSTZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTZ1	0.35541494	0.25	11	4	FALSE	GSTZ1	GSTZ1	214.2222222	0	10	0	0.69773121	FALSE	1	GSTZ1	12230	0.16138763
793084	taxon:9606	2.75909879	4.75E-05	164390	1902	BRI3 binding protein	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane	G:9606:BRI3BP				BRI3BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BRI3BP	0.36243719	0.01818182	11	4	FALSE	BRI3BP	BRI3BP	204.0909091	0	11	0	0.70681687	FALSE	0	BRI3BP	46512	0.12186614
793087	taxon:9606	2.88466992	6.64E-06	180760	1902	polypeptide N-acetylgalactosaminyltransferase 2	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0018242-&&-protein O-linked glycosylation via serine-%%-GO:0018243-&&-protein O-linked glycosylation via threonine-%%-GO:0002378-&&-immunoglobulin biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005795-&&-Golgi stack-%%-GO:0030173-&&-integral component of Golgi membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0030145-&&-manganese ion binding-%%-GO:0004653-&&-polypeptide N-acetylgalactosaminyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:GALNT2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00512-&&-Mucin type O-glycan biosynthesis	GALNT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GALNT2	0.34666011	0.03636364	11	4	FALSE	GALNT2	GALNT2	104.9090909	0	11	0	0.68588835	FALSE	0	GALNT2	7998	0.10966507
793191	taxon:9606	2.74665196	3.96E-06	164174	1902	septin 10	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:SEPT10				SEPT10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEPT10	0.36407962	0.36363636	11	4	FALSE	SEPT10	SEPT10	208.0909091	0	11	0	0.70889134	FALSE	0	SEPT10	8472	0.11654097
793256	taxon:9606	3.52780841	1.14E-05	180431	1902	C-X-C motif chemokine receptor 3	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006915-&&-apoptotic process-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0002685-&&-regulation of leukocyte migration-%%-GO:0001525-&&-angiogenesis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004950-&&-chemokine receptor activity-%%-GO:0016494-&&-C-X-C chemokine receptor activity-%%-GO:0019956-&&-chemokine binding	G:9606:CXCR3			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCR3	0.28346211	0.02777778	11	5	FALSE	CXCR3	CXCR3	11.22222222	0	10	0	0.5786986	FALSE	1	CXCR3	13358	0.17407407
793371	taxon:9606	2.94627383	5.59E-06	180227	1902	integrin subunit alpha L	gene	biological_process-&-1&-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0043113-&&-receptor clustering-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0050900-&&-leukocyte migration-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0002291-&&-T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0006909-&&-phagocytosis-%%-GO:0007159-&&-leukocyte cell-cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0050776-&&-regulation of immune response|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0009986-&&-cell surface-%%-GO:0034687-&&-integrin alphaL-beta2 complex|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0030369-&&-ICAM-3 receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0046872-&&-metal ion binding	G:9606:ITGAL			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05144-&&-Malaria-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05323-&&-Rheumatoid arthritis	ITGAL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGAL	0.33941176	0.13888889	11	5	FALSE	ITGAL	ITGAL	90.88888889	0	10	0	0.67562103	FALSE	1	ITGAL	5874	0.12790333
787130	taxon:9606	2.75389948	2.52E-06	180013	1902	inositol monophosphatase 1	gene	biological_process-&-1&-GO:0006020-&&-inositol metabolic process-%%-GO:0046855-&&-inositol phosphate dephosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0006021-&&-inositol biosynthetic process-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0052832-&&-inositol monophosphate 3-phosphatase activity-%%-GO:0030145-&&-manganese ion binding-%%-GO:0052834-&&-inositol monophosphate phosphatase activity-%%-GO:0008934-&&-inositol monophosphate 1-phosphatase activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0052833-&&-inositol monophosphate 4-phosphatase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031403-&&-lithium ion binding	G:9606:IMPA1			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	IMPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IMPA1	0.36312146	0.21428571	10	4	FALSE	IMPA1	IMPA1	250.5	0	9	0	0.70768342	FALSE	1	IMPA1	4940	0.14498841
787167	taxon:9606	2.8739562	8.57E-06	179939	1902	latent transforming growth factor beta binding protein 3	gene	biological_process-&-1&-GO:1902462-&&-positive regulation of mesenchymal stem cell proliferation-%%-GO:0036363-&&-transforming growth factor beta activation-%%-GO:2000741-&&-positive regulation of mesenchymal stem cell differentiation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0050431-&&-transforming growth factor beta binding-%%-GO:0005509-&&-calcium ion binding	G:9606:LTBP3				LTBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTBP3	0.34795241	0.04444444	10	4	FALSE	LTBP3	LTBP3	113.6	0	10	0	0.68767397	FALSE	0	LTBP3	9150	0.11520408
787193	taxon:9606	2.761147	2.98E-06	179897	1902	MAGE family member A2	gene	biological_process-&-1&-GO:0090398-&&-cellular senescence-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0072331-&&-signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:MAGEA2				MAGEA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA2	0.36216833	0.31111111	10	4	FALSE	MAGEA2	MAGEA2	254	0	10	0	0.7064755	FALSE	0	MAGEA2	5666	0.15522936
787200	taxon:9606	2.76508587	5.79E-06	179881	1902	male germ cell associated kinase	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045494-&&-photoreceptor cell maintenance-%%-GO:0042073-&&-intraciliary transport-%%-GO:0060271-&&-cilium assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:1902856-&&-negative regulation of non-motile cilium assembly-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005930-&&-axoneme-%%-GO:0030496-&&-midbody-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0005929-&&-cilium-%%-GO:0072686-&&-mitotic spindle-%%-GO:0031514-&&-motile cilium-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005634-&&-nucleus-%%-GO:0005813-&&-centrosome-%%-GO:0005737-&&-cytoplasm-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0097542-&&-ciliary tip|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:MAK				MAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAK	0.36165242	0.14285714	10	5	FALSE	MAK	MAK	242.875	0	9	0	0.70581902	FALSE	1	MAK	8224	0.14767194
787285	taxon:9606	2.78588309	6.59E-06	163357	1902	zinc finger and BTB domain containing 49	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001223-&&-transcription coactivator binding	G:9606:ZBTB49				ZBTB49	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB49	0.35895261	0.26666667	10	5	FALSE	ZBTB49	ZBTB49	183.5	0	10	0	0.70235282	FALSE	0	ZBTB49	7772	0.12440678
787321	taxon:9606	2.83362218	1.26E-05	163284	1902	tripartite motif containing 65	gene	biological_process-&-1&-GO:0010508-&&-positive regulation of autophagy|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:TRIM65				TRIM65	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM65	0.3529052	0.04444444	10	4	FALSE	TRIM65	TRIM65	145.3	0	10	0	0.6943963	FALSE	0	TRIM65	12862	0.11376869
787350	taxon:9606	2.8840397	1.10E-05	179609	1902	mitochondrial translational initiation factor 2	gene	biological_process-&-1&-GO:0070124-&&-mitochondrial translational initiation-%%-GO:0006446-&&-regulation of translational initiation-%%-GO:0032790-&&-ribosome disassembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008135-&&-translation factor activity, RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0003743-&&-translation initiation factor activity	G:9606:MTIF2				MTIF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTIF2	0.34673586	0.02222222	10	4	FALSE	MTIF2	MTIF2	110.5	0	10	0	0.68599338	FALSE	0	MTIF2	10852	0.11438999
787586	taxon:9606	2.78052623	6.18E-06	179142	1902	neural EGFL like 1	gene	biological_process-&-1&-GO:1903363-&&-negative regulation of cellular protein catabolic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0007399-&&-nervous system development-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NELL1				NELL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NELL1	0.35964415	0.06666667	10	5	FALSE	NELL1	NELL1	186.6	0	10	0	0.70324563	FALSE	0	NELL1	9644	0.12174198
787657	taxon:9606	2.91476288	1.37E-06	162617	1902	electron transfer flavoprotein beta subunit lysine methyltransferase	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:1904736-&&-negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase-%%-GO:0018023-&&-peptidyl-lysine trimethylation-%%-GO:0018022-&&-peptidyl-lysine methylation-%%-GO:1904733-&&-negative regulation of electron carrier activity|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0016279-&&-protein-lysine N-methyltransferase activity	G:9606:ETFBKMT				ETFBKMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETFBKMT	0.34308108	0.11111111	10	4	FALSE	ETFBKMT	ETFBKMT	128.8	0	10	0	0.68087285	FALSE	0	ETFBKMT	3098	0.17361299
787705	taxon:9606	2.83960926	3.05E-06	162530	1902	ring finger protein 144B	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0006915-&&-apoptotic process-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031966-&&-mitochondrial membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF144B				RNF144B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF144B	0.35216113	0.11111111	10	4	FALSE	RNF144B	RNF144B	159.1	0	10	0	0.69339846	FALSE	0	RNF144B	6138	0.12976288
787877	taxon:9606	2.86340003	3.68E-06	162282	1902	growth arrest specific 2 like 3	gene	biological_process-&-1&-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0000226-&&-microtubule cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding	G:9606:GAS2L3				GAS2L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAS2L3	0.34923517	0.26666667	10	5	FALSE	GAS2L3	GAS2L3	163.3	0	10	0	0.68943333	FALSE	0	GAS2L3	5248	0.14489796
787969	taxon:9606	2.88482748	7.50E-06	178490	1902	propionyl-CoA carboxylase alpha subunit	gene	biological_process-&-1&-GO:0019626-&&-short-chain fatty acid catabolic process-%%-GO:0006768-&&-biotin metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004658-&&-propionyl-CoA carboxylase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0009374-&&-biotin binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004075-&&-biotin carboxylase activity	G:9606:PCCA			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	PCCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCCA	0.34664118	0.11111111	10	5	FALSE	PCCA	PCCA	123.4	0	10	0	0.68586209	FALSE	0	PCCA	8638	0.12414141
788007	taxon:9606	2.761147	2.98E-06	162025	1902	MAGE family member A2B	gene	biological_process-&-1&-GO:0090398-&&-cellular senescence-%%-GO:0044257-&&-cellular protein catabolic process-%%-GO:1901984-&&-negative regulation of protein acetylation-%%-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity-%%-GO:0072331-&&-signal transduction by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0033234-&&-negative regulation of protein sumoylation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0042826-&&-histone deacetylase binding-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0070491-&&-repressing transcription factor binding-%%-GO:0005515-&&-protein binding	G:9606:MAGEA2B				MAGEA2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA2B	0.36216833	0.31111111	10	4	FALSE	MAGEA2B	MAGEA2B	254	0	10	0	0.7064755	FALSE	0	MAGEA2B	5666	0.15522936
788031	taxon:9606	2.85331653	1.52E-05	178334	1902	roundabout guidance receptor 1	gene	biological_process-&-1&-GO:0050772-&&-positive regulation of axonogenesis-%%-GO:0070100-&&-negative regulation of chemokine-mediated signaling pathway-%%-GO:0021836-&&-chemorepulsion involved in postnatal olfactory bulb interneuron migration-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0007507-&&-heart development-%%-GO:0035385-&&-Roundabout signaling pathway-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0007399-&&-nervous system development-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0033600-&&-negative regulation of mammary gland epithelial cell proliferation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0007411-&&-axon guidance-%%-GO:0016199-&&-axon midline choice point recognition-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0050925-&&-negative regulation of negative chemotaxis-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0030275-&&-LRR domain binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0008046-&&-axon guidance receptor activity	G:9606:ROBO1			KEGG-&-1&-hsa04360-&&-Axon guidance	ROBO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROBO1	0.35046935	0.04444444	10	4	FALSE	ROBO1	ROBO1	137.5	0	10	0	0.69111391	FALSE	0	ROBO1	13990	0.11885317
788210	taxon:9606	2.88782102	9.00E-06	178075	1902	recoverin	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0051924-&&-regulation of calcium ion transport-%%-GO:0007602-&&-phototransduction-%%-GO:0007165-&&-signal transduction-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity|cellular_component-&-1&-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0008048-&&-calcium sensitive guanylate cyclase activator activity	G:9606:RCVRN			KEGG-&-1&-hsa04744-&&-Phototransduction	RCVRN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCVRN	0.34628185	0.13333333	10	5	FALSE	RCVRN	RCVRN	105.4	0	10	0	0.68536316	FALSE	0	RCVRN	9018	0.11729911
788218	taxon:9606	2.93177879	2.46E-06	178056	1902	REV3 like, DNA directed polymerase zeta catalytic subunit	gene	biological_process-&-1&-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0042276-&&-error-prone translesion synthesis-%%-GO:0006261-&&-DNA-dependent DNA replication|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016035-&&-zeta DNA polymerase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003677-&&-DNA binding-%%-GO:0008408-&&-3'-5' exonuclease activity-%%-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003887-&&-DNA-directed DNA polymerase activity	G:9606:REV3L			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway-%%-hsa01524-&&-Platinum drug resistance	REV3L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REV3L	0.34108985	0.06666667	10	5	FALSE	REV3L	REV3L	94.2	0	10	0	0.67803687	FALSE	0	REV3L	3484	0.11654229
788252	taxon:9606	2.84149992	1.25E-05	178000	1902	regulator of G-protein signaling 4	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0045744-&&-negative regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005516-&&-calmodulin binding	G:9606:RGS4				RGS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS4	0.35192681	0.17777778	10	4	FALSE	RGS4	RGS4	147	0	10	0	0.69308335	FALSE	0	RGS4	12428	0.1202946
788255	taxon:9606	2.74885773	6.38E-06	177998	1902	regulator of G-protein signaling 10	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0043197-&&-dendritic spine-%%-GO:0043679-&&-axon terminus-%%-GO:0005886-&&-plasma membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0001965-&&-G-protein alpha-subunit binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS10				RGS10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS10	0.36378747	0.2	10	4	FALSE	RGS10	RGS10	207.4	0	10	0	0.70852371	FALSE	0	RGS10	14748	0.12202591
788299	taxon:9606	2.84465102	9.50E-06	177935	1902	RRAD, Ras related glycolysis inhibitor and calcium channel regulator	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:RRAD				RRAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RRAD	0.35153697	0.04444444	10	4	FALSE	RRAD	RRAD	151.2	0	10	0	0.69255816	FALSE	0	RRAD	12482	0.13178634
788345	taxon:9606	3.33118009	2.62E-06	177838	1902	C-C motif chemokine ligand 4	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007163-&&-establishment or maintenance of cell polarity-%%-GO:0009615-&&-response to virus-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0050850-&&-positive regulation of calcium-mediated signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0043922-&&-negative regulation by host of viral transcription-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:2000503-&&-positive regulation of natural killer cell chemotaxis-%%-GO:0051928-&&-positive regulation of calcium ion transport-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0009636-&&-response to toxic substance-%%-GO:0007155-&&-cell adhesion-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0031726-&&-CCR1 chemokine receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0031730-&&-CCR5 chemokine receptor binding	G:9606:CCL4			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL4	0.30019392	0.42857143	10	5	FALSE	CCL4	CCL4	21.125	0	9	0	0.61146999	FALSE	1	CCL4	3712	0.18530702
788346	taxon:9606	2.8624547	1.43E-04	177833	1902	C-C motif chemokine ligand 13	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048245-&&-eosinophil chemotaxis|cellular_component-&-1&-GO:0005623-&&-cell-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL13			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL13	0.34935051	0.04444444	10	4	FALSE	CCL13	CCL13	122.1	0	10	0	0.68959088	FALSE	0	CCL13	121582	0.10780834
788348	taxon:9606	3.23349614	1.73E-05	177834	1902	C-C motif chemokine ligand 11	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002551-&&-mast cell chemotaxis-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0006935-&&-chemotaxis-%%-GO:0009314-&&-response to radiation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0035962-&&-response to interleukin-13-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0007155-&&-cell adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0070670-&&-response to interleukin-4-%%-GO:0007015-&&-actin filament organization-%%-GO:0060763-&&-mammary duct terminal end bud growth-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0060444-&&-branching involved in mammary gland duct morphogenesis-%%-GO:0009615-&&-response to virus-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0030335-&&-positive regulation of cell migration|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0048020-&&-CCR chemokine receptor binding-%%-GO:0008009-&&-chemokine activity	G:9606:CCL11			KEGG-&-1&-hsa05310-&&-Asthma-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL11	0.30926278	0.03571429	10	5	FALSE	CCL11	CCL11	25.25	0	9	0	0.62775064	FALSE	1	CCL11	23760	0.16780822
788652	taxon:9606	3.01197416	3.32E-06	177251	1902	thyroglobulin	gene	biological_process-&-1&-GO:0015705-&&-iodide transport-%%-GO:0042403-&&-thyroid hormone metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0042446-&&-hormone biosynthetic process-%%-GO:0030878-&&-thyroid gland development-%%-GO:0031641-&&-regulation of myelination|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005179-&&-hormone activity	G:9606:TG			KEGG-&-1&-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04918-&&-Thyroid hormone synthesis	TG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TG	0.33200816	0.17857143	10	5	FALSE	TG	TG	70.125	0	9	0	0.66467097	FALSE	1	TG	2832	0.16296729
788654	taxon:9606	2.92847014	5.10E-06	177244	1902	transforming growth factor beta induced	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0001525-&&-angiogenesis-%%-GO:0008283-&&-cell proliferation-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0050896-&&-response to stimulus-%%-GO:0007601-&&-visual perception-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0050840-&&-extracellular matrix binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding	G:9606:TGFBI				TGFBI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TGFBI	0.34147522	0.2	10	5	FALSE	TGFBI	TGFBI	101	0	10	0	0.67858831	FALSE	0	TGFBI	4880	0.11693735
788684	taxon:9606	2.58247991	1.26E-05	160818	1902	ankyrin repeat domain 13D	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005770-&&-late endosome	G:9606:ANKRD13D				ANKRD13D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD13D	0.3872247	0.28888889	10	4	FALSE	ANKRD13D	ANKRD13D	389.2	0	10	0	0.73625335	FALSE	0	ANKRD13D	22830	0.14441558
788740	taxon:9606	2.91003624	2.10E-07	177057	1902	testis specific protein, Y-linked 1	gene	biological_process-&-1&-GO:0007506-&&-gonadal mesoderm development-%%-GO:0007548-&&-sex differentiation-%%-GO:0008283-&&-cell proliferation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TSPY1				TSPY1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPY1	0.34363833	0.67857143	10	5	FALSE	TSPY1	TSPY1	131.375	0	9	0	0.68166063	FALSE	1	TSPY1	878	0.16380923
788866	taxon:9606	3.09106665	1.70E-05	176735	1902	vascular endothelial growth factor B	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0042493-&&-response to drug-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0001666-&&-response to hypoxia|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0043183-&&-vascular endothelial growth factor receptor 1 binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding	G:9606:VEGFB			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway	VEGFB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VEGFB	0.32351292	0.14285714	10	5	FALSE	VEGFB	VEGFB	52.5	0	9	0	0.65148889	FALSE	1	VEGFB	14436	0.13402062
789038	taxon:9606	2.79580904	5.40E-06	159931	1902	tripartite motif containing 74	gene	cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:TRIM74				TRIM74	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM74	0.35767822	0.08888889	10	5	FALSE	TRIM74	TRIM74	175.7	0	10	0	0.70069849	FALSE	0	TRIM74	8822	0.12209059
789059	taxon:9606	2.90231605	4.50E-06	176271	1902	succinate-CoA ligase alpha subunit	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004775-&&-succinate-CoA ligase (ADP-forming) activity-%%-GO:0004776-&&-succinate-CoA ligase (GDP-forming) activity-%%-GO:0048037-&&-cofactor binding	G:9606:SUCLG1	SUCLG1	TRUE	KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism	SUCLG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUCLG1	0.34455241	0.24444444	10	4	FALSE	SUCLG1	SUCLG1	111.3	0	10	0	0.68294732	FALSE	0	SUCLG1	5204	0.11790254
789072	taxon:9606	3.10808256	1.54E-05	176247	1902	neuropilin 2	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0038084-&&-vascular endothelial growth factor signaling pathway-%%-GO:0048846-&&-axon extension involved in axon guidance-%%-GO:0007411-&&-axon guidance-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0097490-&&-sympathetic neuron projection extension-%%-GO:0021675-&&-nerve development-%%-GO:1902285-&&-semaphorin-plexin signaling pathway involved in neuron projection guidance-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0097491-&&-sympathetic neuron projection guidance|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0002116-&&-semaphorin receptor complex|molecular_function-&-1&-GO:0019955-&&-cytokine binding-%%-GO:0008201-&&-heparin binding-%%-GO:0004872-&&-receptor activity-%%-GO:0017154-&&-semaphorin receptor activity-%%-GO:0005021-&&-vascular endothelial growth factor-activated receptor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0019838-&&-growth factor binding	G:9606:NRP2				NRP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRP2	0.32174178	0.2	10	5	FALSE	NRP2	NRP2	34.1	0	10	0	0.64865291	FALSE	0	NRP2	16568	0.1162069
789091	taxon:9606	2.79659682	4.20E-06	176210	1902	cell division cycle 123	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0051301-&&-cell division-%%-GO:0007050-&&-cell cycle arrest-%%-GO:1905143-&&-eukaryotic translation initiation factor 2 complex assembly-%%-GO:0045948-&&-positive regulation of translational initiation-%%-GO:0006417-&&-regulation of translation|cellular_component-&-1&-GO:0005737-&&-cytoplasm	G:9606:CDC123				CDC123	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC123	0.35757746	0.13333333	10	4	FALSE	CDC123	CDC123	191.4	0	10	0	0.7005672	FALSE	0	CDC123	7902	0.12748499
789135	taxon:9606	3.33118009	2.62E-06	159754	1902	C-C motif chemokine ligand 4 like 1	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL4L1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05132-&&-Salmonella infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	CCL4L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL4L1	0.30019392	0.42857143	10	5	FALSE	CCL4L1	CCL4L1	21.125	0	9	0	0.61146999	FALSE	1	CCL4L1	3712	0.18530702
789189	taxon:9606	2.84023948	6.40E-07	176035	1902	histone cluster 1 H2B family member o	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BO			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BO	0.35208299	0.26666667	10	4	FALSE	HIST1H2BO	HIST1H2BO	228.8	0	10	0	0.69329342	FALSE	0	HIST1H2BO	3546	0.18963516
789391	taxon:9606	3.01859146	6.03E-06	175589	1902	cytohesin 3	gene	biological_process-&-1&-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0048193-&&-Golgi vesicle transport-%%-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0001726-&&-ruffle|molecular_function-&-1&-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:CYTH3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04072-&&-Phospholipase D signaling pathway	CYTH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYTH3	0.33128034	0.04444444	10	5	FALSE	CYTH3	CYTH3	48.8	0	10	0	0.66356809	FALSE	0	CYTH3	5166	0.11394799
789437	taxon:9606	3.25807468	4.70E-05	175473	1902	adiponectin, C1Q and collagen domain containing	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0032270-&&-positive regulation of cellular protein metabolic process-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:2000481-&&-positive regulation of cAMP-dependent protein kinase activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032757-&&-positive regulation of interleukin-8 production-%%-GO:0050765-&&-negative regulation of phagocytosis-%%-GO:2000590-&&-negative regulation of metanephric mesenchymal cell migration-%%-GO:0010739-&&-positive regulation of protein kinase A signaling-%%-GO:0045650-&&-negative regulation of macrophage differentiation-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0070208-&&-protein heterotrimerization-%%-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0007584-&&-response to nutrient-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:2000534-&&-positive regulation of renal albumin absorption-%%-GO:0010875-&&-positive regulation of cholesterol efflux-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0046888-&&-negative regulation of hormone secretion-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0060081-&&-membrane hyperpolarization-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045721-&&-negative regulation of gluconeogenesis-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:1900121-&&-negative regulation of receptor binding-%%-GO:0071639-&&-positive regulation of monocyte chemotactic protein-1 production-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0010745-&&-negative regulation of macrophage derived foam cell differentiation-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:2000478-&&-positive regulation of metanephric glomerular visceral epithelial cell development-%%-GO:0033034-&&-positive regulation of myeloid cell apoptotic process-%%-GO:0070994-&&-detection of oxidative stress-%%-GO:0009744-&&-response to sucrose-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0001666-&&-response to hypoxia-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:2000584-&&-negative regulation of platelet-derived growth factor receptor-alpha signaling pathway-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0034612-&&-response to tumor necrosis factor-%%-GO:0007623-&&-circadian rhythm-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0010642-&&-negative regulation of platelet-derived growth factor receptor signaling pathway-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0009749-&&-response to glucose-%%-GO:0010804-&&-negative regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:2000467-&&-positive regulation of glycogen (starch) synthase activity-%%-GO:0050805-&&-negative regulation of synaptic transmission-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0014823-&&-response to activity-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0030853-&&-negative regulation of granulocyte differentiation-%%-GO:0035690-&&-cellular response to drug-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0045715-&&-negative regulation of low-density lipoprotein particle receptor biosynthetic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0045923-&&-positive regulation of fatty acid metabolic process-%%-GO:0051899-&&-membrane depolarization-%%-GO:0090317-&&-negative regulation of intracellular protein transport-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0070543-&&-response to linoleic acid-%%-GO:0045471-&&-response to ethanol-%%-GO:0014912-&&-negative regulation of smooth muscle cell migration|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0033691-&&-sialic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0005179-&&-hormone activity	G:9606:ADIPOQ	ADIPOQ	TRUE	KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	ADIPOQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADIPOQ	0.30692974	0.07142857	10	5	FALSE	ADIPOQ	ADIPOQ	26	0	9	0	0.62365422	FALSE	1	ADIPOQ	29080	0.13492063
789456	taxon:9606	2.80100835	1.36E-05	175425	1902	RAB3D, member RAS oncogene family	gene	biological_process-&-1&-GO:0018125-&&-peptidyl-cysteine methylation-%%-GO:0045453-&&-bone resorption-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0015031-&&-protein transport-%%-GO:1903307-&&-positive regulation of regulated secretory pathway-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0035577-&&-azurophil granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0099503-&&-secretory vesicle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0042588-&&-zymogen granule-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0005525-&&-GTP binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0003924-&&-GTPase activity	G:9606:RAB3D			KEGG-&-1&-hsa04972-&&-Pancreatic secretion	RAB3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB3D	0.35701429	0.26666667	10	4	FALSE	RAB3D	RAB3D	161.2	0	10	0	0.69983194	FALSE	0	RAB3D	12012	0.11548387
789457	taxon:9606	2.62139594	3.74E-06	175424	1902	amyloid beta precursor protein binding family A member 3	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0004857-&&-enzyme inhibitor activity	G:9606:APBA3				APBA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBA3	0.38147614	0.26666667	10	4	FALSE	APBA3	APBA3	328.4	0	10	0	0.72976734	FALSE	0	APBA3	8274	0.13313058
789494	taxon:9606	2.61603907	9.39E-06	175337	1902	suppressor of cytokine signaling 5	gene	biological_process-&-1&-GO:0016049-&&-cell growth-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0097699-&&-vascular endothelial cell response to fluid shear stress-%%-GO:0071638-&&-negative regulation of monocyte chemotactic protein-1 production-%%-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0071404-&&-cellular response to low-density lipoprotein particle stimulus-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0045629-&&-negative regulation of T-helper 2 cell differentiation-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0045627-&&-positive regulation of T-helper 1 cell differentiation-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0040008-&&-regulation of growth-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:SOCS5			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway	SOCS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOCS5	0.38225729	0.15555556	10	4	FALSE	SOCS5	SOCS5	336.9	0	10	0	0.73066015	FALSE	0	SOCS5	23186	0.13578056
789518	taxon:9606	2.69339846	4.20E-06	175287	1902	USP6 N-terminal like	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0019068-&&-virion assembly-%%-GO:0048227-&&-plasma membrane to endosome transport-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0035526-&&-retrograde transport, plasma membrane to Golgi-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:1903358-&&-regulation of Golgi organization-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:USP6NL				USP6NL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP6NL	0.37127815	0.08888889	10	4	FALSE	USP6NL	USP6NL	249.2	0	10	0	0.71776692	FALSE	0	USP6NL	10810	0.12330193
789530	taxon:9606	2.8541043	1.60E-05	175251	1902	ATPase phospholipid transporting 9A (putative)	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0045332-&&-phospholipid translocation-%%-GO:0006897-&&-endocytosis|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0055037-&&-recycling endosome-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004012-&&-phospholipid-translocating ATPase activity	G:9606:ATP9A				ATP9A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATP9A	0.35037262	0.02222222	10	4	FALSE	ATP9A	ATP9A	128.3	0	10	0	0.69098262	FALSE	0	ATP9A	15020	0.11125654
789878	taxon:9606	2.86087916	4.74E-06	174455	1902	membrane associated ring-CH-type finger 6	gene	biological_process-&-1&-GO:1904380-&&-endoplasmic reticulum mannose trimming-%%-GO:0010498-&&-proteasomal protein catabolic process-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0036503-&&-ERAD pathway-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0044322-&&-endoplasmic reticulum quality control compartment-%%-GO:0030176-&&-integral component of endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0000835-&&-ER ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:1990381-&&-ubiquitin-specific protease binding-%%-GO:0019899-&&-enzyme binding-%%-GO:1904264-&&-ubiquitin protein ligase activity involved in ERAD pathway	G:9606:MARCH6			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	6-Mar	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCH6	0.3495429	0.14285714	10	4	FALSE	6-Mar	6-Mar	164.25	0	9	0	0.68985347	FALSE	1	6-Mar	5012	0.15173611
789885	taxon:9606	2.87458642	5.77E-06	174435	1902	kelch like family member 41	gene	biological_process-&-1&-GO:0031275-&&-regulation of lateral pseudopodium assembly-%%-GO:0045661-&&-regulation of myoblast differentiation-%%-GO:0006941-&&-striated muscle contraction-%%-GO:2000291-&&-regulation of myoblast proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:2001014-&&-regulation of skeletal muscle cell differentiation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0030239-&&-myofibril assembly-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0048741-&&-skeletal muscle fiber development|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031430-&&-M band-%%-GO:0005856-&&-cytoskeleton-%%-GO:0033017-&&-sarcoplasmic reticulum membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0001726-&&-ruffle-%%-GO:0031143-&&-pseudopodium|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:KLHL41				KLHL41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL41	0.34787613	0.03571429	10	4	FALSE	KLHL41	KLHL41	157.625	0	9	0	0.68756893	FALSE	1	KLHL41	8966	0.13882743
789896	taxon:9606	2.96959193	2.57E-05	174411	1902	prolyl 3-hydroxylase family member 4 (non-enzymatic)	gene	biological_process-&-1&-GO:0007130-&&-synaptonemal complex assembly|cellular_component-&-1&-GO:0000794-&&-condensed nuclear chromosome-%%-GO:0000795-&&-synaptonemal complex-%%-GO:0005730-&&-nucleolus	G:9606:P3H4				P3H4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P3H4	0.3367466	0.02222222	10	4	FALSE	P3H4	P3H4	66	0	10	0	0.67173468	FALSE	0	P3H4	21264	0.10516129
789900	taxon:9606	2.78698598	5.10E-07	158017	1902	histone cluster 2 H2B family member f	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000786-&&-nucleosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST2H2BF			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST2H2BF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST2H2BF	0.35881056	0.31111111	10	4	FALSE	HIST2H2BF	HIST2H2BF	295.4	0	10	0	0.702169	FALSE	0	HIST2H2BF	3892	0.19243807
789903	taxon:9606	2.75846857	4.42E-06	174396	1902	tripartite motif containing 16	gene	biological_process-&-1&-GO:0046683-&&-response to organophosphorus-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0048386-&&-positive regulation of retinoic acid receptor signaling pathway-%%-GO:0043967-&&-histone H4 acetylation-%%-GO:0060416-&&-response to growth hormone|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016605-&&-PML body|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003677-&&-DNA binding-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0032089-&&-NACHT domain binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM16				TRIM16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM16	0.36251999	0.28888889	10	5	FALSE	TRIM16	TRIM16	211.2	0	10	0	0.70692191	FALSE	0	TRIM16	8394	0.12716867
789923	taxon:9606	3.0282023	7.45E-06	174348	1902	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing-%%-GO:0007411-&&-axon guidance-%%-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0030311-&&-poly-N-acetyllactosamine biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008532-&&-N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity-%%-GO:0008499-&&-UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	G:9606:B3GNT2			KEGG-&-1&-hsa00533-&&-Glycosaminoglycan biosynthesis - keratan sulfate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00601-&&-Glycosphingolipid biosynthesis - lacto and neolacto series	B3GNT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B3GNT2	0.33022893	0	10	5	FALSE	B3GNT2	B3GNT2	39.2	0	10	0	0.66196628	FALSE	0	B3GNT2	6294	0.11646341
789953	taxon:9606	2.79502127	2.83E-06	174253	1902	WAS protein family member 3	gene	biological_process-&-1&-GO:0014003-&&-oligodendrocyte development-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0031643-&&-positive regulation of myelination-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0006461-&&-protein complex assembly|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030027-&&-lamellipodium-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003779-&&-actin binding	G:9606:WASF3			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04520-&&-Adherens junction	WASF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WASF3	0.35777903	0.28888889	10	5	FALSE	WASF3	WASF3	189	0	10	0	0.70082979	FALSE	0	WASF3	5206	0.13147632
790040	taxon:9606	2.74854262	5.60E-06	174034	1902	tubulin polymerization promoting protein	gene	biological_process-&-1&-GO:0046785-&&-microtubule polymerization-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0032273-&&-positive regulation of protein polymerization-%%-GO:0031334-&&-positive regulation of protein complex assembly|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0043209-&&-myelin sheath-%%-GO:0005829-&&-cytosol-%%-GO:0005874-&&-microtubule-%%-GO:0005739-&&-mitochondrion-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008017-&&-microtubule binding-%%-GO:0015631-&&-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:TPPP				TPPP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TPPP	0.36382918	0.28571429	10	4	FALSE	TPPP	TPPP	262.25	0	9	0	0.70857623	FALSE	1	TPPP	6124	0.15366569
790084	taxon:9606	2.84795967	1.85E-06	157534	1902	TRIM6-TRIM34 readthrough	gene		G:9606:TRIM6-TRIM34				TRIM6-TRIM34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM6-TRIM34	0.35112857	0.28571429	10	4	FALSE	TRIM6-TRIM34	TRIM6-TRIM34	179.375	0	9	0	0.69200672	FALSE	1	TRIM6-TRIM34	3226	0.15035624
790100	taxon:9606	2.8060501	5.27E-06	173872	1902	TBC1 domain family member 1	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0061024-&&-membrane organization-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005829-&&-cytosol-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D1			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway	TBC1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D1	0.35637282	0.15555556	10	4	FALSE	TBC1D1	TBC1D1	207.1	0	10	0	0.69899165	FALSE	0	TBC1D1	7614	0.14831541
790180	taxon:9606	2.66945013	6.87E-06	173706	1902	MON2 homolog, regulator of endosome-to-Golgi trafficking	gene	biological_process-&-1&-GO:0006895-&&-Golgi to endosome transport-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MON2				MON2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MON2	0.37460898	0.15555556	10	4	FALSE	MON2	MON2	304.7	0	10	0	0.72175831	FALSE	0	MON2	14738	0.13765823
790213	taxon:9606	2.69954309	6.06E-06	173619	1902	NAC alpha domain containing	gene	biological_process-&-1&-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:NACAD				NACAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NACAD	0.37043306	0.15555556	10	4	FALSE	NACAD	NACAD	248.1	0	10	0	0.71674282	FALSE	0	NACAD	9740	0.12347956
790291	taxon:9606	2.65148889	1.16E-05	173414	1902	calpain 7	gene	biological_process-&-1&-GO:0097264-&&-self proteolysis-%%-GO:0010634-&&-positive regulation of epithelial cell migration|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0090541-&&-MIT domain binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004198-&&-calcium-dependent cysteine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:CAPN7				CAPN7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAPN7	0.37714659	0.08888889	10	4	FALSE	CAPN7	CAPN7	304.6	0	10	0	0.72475185	FALSE	0	CAPN7	18320	0.13254902
790294	taxon:9606	2.90798803	1.47E-05	173401	1902	SAM pointed domain containing ETS transcription factor	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010454-&&-negative regulation of cell fate commitment-%%-GO:0030154-&&-cell differentiation-%%-GO:0060576-&&-intestinal epithelial cell development-%%-GO:0060480-&&-lung goblet cell differentiation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0010455-&&-positive regulation of cell fate commitment|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:SPDEF				SPDEF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPDEF	0.34388037	0	10	4	FALSE	SPDEF	SPDEF	97	0	10	0	0.682002	FALSE	0	SPDEF	11914	0.11034483
790477	taxon:9606	2.75059083	7.36E-06	172739	1902	low density lipoprotein receptor adaptor protein 1	gene	biological_process-&-1&-GO:0008203-&&-cholesterol metabolic process-%%-GO:0061024-&&-membrane organization-%%-GO:0090003-&&-regulation of establishment of protein localization to plasma membrane-%%-GO:0090118-&&-receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0034383-&&-low-density lipoprotein particle clearance-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0043393-&&-regulation of protein binding-%%-GO:0090205-&&-positive regulation of cholesterol metabolic process-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0031623-&&-receptor internalization-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:1905602-&&-positive regulation of receptor-mediated endocytosis involved in cholesterol transport-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0030121-&&-AP-1 adaptor complex-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0030665-&&-clathrin-coated vesicle membrane-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0030122-&&-AP-2 adaptor complex-%%-GO:0055037-&&-recycling endosome-%%-GO:0005883-&&-neurofilament|molecular_function-&-1&-GO:0030276-&&-clathrin binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0001784-&&-phosphotyrosine binding-%%-GO:0035612-&&-AP-2 adaptor complex binding-%%-GO:0005515-&&-protein binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0030159-&&-receptor signaling complex scaffold activity-%%-GO:0005546-&&-phosphatidylinositol-4,5-bisphosphate binding-%%-GO:0035591-&&-signaling adaptor activity-%%-GO:0035615-&&-clathrin adaptor activity	G:9606:LDLRAP1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04979-&&-Cholesterol metabolism	LDLRAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LDLRAP1	0.36355825	0.17777778	10	5	FALSE	LDLRAP1	LDLRAP1	204.4	0	10	0	0.70823486	FALSE	0	LDLRAP1	10100	0.12095915
790488	taxon:9606	2.93004569	2.67E-06	172719	1902	N-acetyltransferase 9 (putative)	gene	cellular_component-&-1&-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008080-&&-N-acetyltransferase activity	G:9606:NAT9				NAT9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAT9	0.34129161	0.14285714	10	5	FALSE	NAT9	NAT9	116.125	0	9	0	0.67832572	FALSE	1	NAT9	3320	0.13979469
790509	taxon:9606	2.71120214	2.42E-06	172655	1902	F-box protein 9	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO9				FBXO9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO9	0.36884007	0.46666667	10	4	FALSE	FBXO9	FBXO9	307.7	0	10	0	0.71479964	FALSE	0	FBXO9	5632	0.15731084
790552	taxon:9606	2.76067433	4.27E-06	172253	1902	protein tyrosine phosphatase, non-receptor type 18	gene	biological_process-&-1&-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004726-&&-non-membrane spanning protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:PTPN18				PTPN18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN18	0.36223034	0.46666667	10	4	FALSE	PTPN18	PTPN18	255.6	0	10	0	0.70655428	FALSE	0	PTPN18	6654	0.15560292
790612	taxon:9606	2.80463211	4.44E-06	171760	1902	TAO kinase 3	gene	biological_process-&-1&-GO:0046329-&&-negative regulation of JNK cascade-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007095-&&-mitotic G2 DNA damage checkpoint-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0043507-&&-positive regulation of JUN kinase activity-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0032874-&&-positive regulation of stress-activated MAPK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006281-&&-DNA repair-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016740-&&-transferase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity	G:9606:TAOK3			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	TAOK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAOK3	0.356553	0.14285714	10	5	FALSE	TAOK3	TAOK3	211.25	0	9	0	0.69922798	FALSE	1	TAOK3	5974	0.15249638
790634	taxon:9606	2.87411375	4.32E-06	171701	1902	leucine carboxyl methyltransferase 1	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0031333-&&-negative regulation of protein complex assembly-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006481-&&-C-terminal protein methylation-%%-GO:0090266-&&-regulation of mitotic cell cycle spindle assembly checkpoint-%%-GO:0006479-&&-protein methylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0018423-&&-protein C-terminal leucine carboxyl O-methyltransferase activity-%%-GO:0003880-&&-protein C-terminal carboxyl O-methyltransferase activity-%%-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:LCMT1				LCMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCMT1	0.34793334	0.15555556	10	4	FALSE	LCMT1	LCMT1	124.3	0	10	0	0.68764771	FALSE	0	LCMT1	5586	0.12889813
790673	taxon:9606	2.8506381	5.21E-06	171531	1902	Kruppel like factor 15	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:1901653-&&-cellular response to peptide-%%-GO:0010001-&&-glial cell differentiation-%%-GO:0072112-&&-glomerular visceral epithelial cell differentiation-%%-GO:2000757-&&-negative regulation of peptidyl-lysine acetylation-%%-GO:0015758-&&-glucose transport-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:KLF15				KLF15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF15	0.35079865	0.15555556	10	5	FALSE	KLF15	KLF15	158.1	0	10	0	0.69156032	FALSE	0	KLF15	8468	0.13985828
790697	taxon:9606	2.91003624	2.10E-07	155053	1902	testis specific protein, Y-linked 3	gene	biological_process-&-1&-GO:0007506-&&-gonadal mesoderm development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:TSPY3				TSPY3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPY3	0.34363833	0.67857143	10	5	FALSE	TSPY3	TSPY3	131.375	0	9	0	0.68166063	FALSE	1	TSPY3	878	0.16380923
790717	taxon:9606	2.86655113	9.98E-06	171399	1902	GDP-mannose pyrophosphorylase A	gene	biological_process-&-1&-GO:0009058-&&-biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0016779-&&-nucleotidyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:GMPPA			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	GMPPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMPPA	0.34885127	0.03571429	10	5	FALSE	GMPPA	GMPPA	156.5	0	9	0	0.68890815	FALSE	1	GMPPA	10000	0.13449914
790726	taxon:9606	2.86796912	1.03E-05	171379	1902	adiponectin receptor 1	gene	biological_process-&-1&-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0019395-&&-fatty acid oxidation-%%-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:1901223-&&-negative regulation of NIK/NF-kappaB signaling-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0019216-&&-regulation of lipid metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0097003-&&-adipokinetic hormone receptor activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0055100-&&-adiponectin binding-%%-GO:0046872-&&-metal ion binding	G:9606:ADIPOR1	ADIPOR1	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	ADIPOR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADIPOR1	0.34867879	0.03571429	10	4	FALSE	ADIPOR1	ADIPOR1	148	0	9	0	0.68867181	FALSE	1	ADIPOR1	11088	0.13997148
790755	taxon:9606	2.8722231	3.70E-06	171324	1902	hematological and neurological expressed 1	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005730-&&-nucleolus	G:9606:HN1				HN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HN1	0.34816237	0.06666667	10	4	FALSE	HN1	HN1	129.6	0	10	0	0.68796282	FALSE	0	HN1	4728	0.12884232
790849	taxon:9606	2.91161179	3.93E-06	170913	1902	receptor interacting serine/threonine kinase 4	gene	biological_process-&-1&-GO:0002009-&&-morphogenesis of an epithelium-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:RIPK4				RIPK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIPK4	0.34345238	0.15555556	10	5	FALSE	RIPK4	RIPK4	105.5	0	10	0	0.68139804	FALSE	0	RIPK4	5646	0.13504493
790857	taxon:9606	2.82117536	2.83E-05	170877	1902	Wnt family member 4	gene	biological_process-&-1&-GO:0072034-&&-renal vesicle induction-%%-GO:0030182-&&-neuron differentiation-%%-GO:2000225-&&-negative regulation of testosterone biosynthetic process-%%-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0008584-&&-male gonad development-%%-GO:0010894-&&-negative regulation of steroid biosynthetic process-%%-GO:0001822-&&-kidney development-%%-GO:0030325-&&-adrenal gland development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0001838-&&-embryonic epithelial tube formation-%%-GO:0001837-&&-epithelial to mesenchymal transition-%%-GO:0045836-&&-positive regulation of meiotic nuclear division-%%-GO:0072033-&&-renal vesicle formation-%%-GO:0038030-&&-non-canonical Wnt signaling pathway via MAPK cascade-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0060748-&&-tertiary branching involved in mammary gland duct morphogenesis-%%-GO:0072174-&&-metanephric tubule formation-%%-GO:0032349-&&-positive regulation of aldosterone biosynthetic process-%%-GO:0061180-&&-mammary gland epithelium development-%%-GO:0061045-&&-negative regulation of wound healing-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0072162-&&-metanephric mesenchymal cell differentiation-%%-GO:0022407-&&-regulation of cell-cell adhesion-%%-GO:0048599-&&-oocyte development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0061184-&&-positive regulation of dermatome development-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:2000019-&&-negative regulation of male gonad development-%%-GO:0008585-&&-female gonad development-%%-GO:0030237-&&-female sex determination-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:2000066-&&-positive regulation of cortisol biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0033080-&&-immature T cell proliferation in thymus-%%-GO:0051894-&&-positive regulation of focal adhesion assembly-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0045165-&&-cell fate commitment-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0072273-&&-metanephric nephron morphogenesis-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0060126-&&-somatotropin secreting cell differentiation-%%-GO:0061369-&&-negative regulation of testicular blood vessel morphogenesis-%%-GO:0060231-&&-mesenchymal to epithelial transition-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0061205-&&-paramesonephric duct development-%%-GO:0060129-&&-thyroid-stimulating hormone-secreting cell differentiation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0048018-&&-receptor agonist activity	G:9606:WNT4	WNT4	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	WNT4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNT4	0.35446219	0.02222222	10	5	FALSE	WNT4	WNT4	142	0	10	0	0.69647077	FALSE	0	WNT4	29134	0.1078686
790879	taxon:9606	2.79706948	5.32E-06	170794	1902	chymotrypsin like elastase family member 2B	gene	biological_process-&-1&-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity	G:9606:CELA2B			KEGG-&-1&-hsa04972-&&-Pancreatic secretion-%%-hsa04974-&&-Protein digestion and absorption	CELA2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CELA2B	0.35751704	0.06666667	10	4	FALSE	CELA2B	CELA2B	177.6	0	10	0	0.70048842	FALSE	0	CELA2B	9472	0.12273042
791011	taxon:9606	2.87490153	1.46E-05	170392	1902	NSE4 homolog A, SMC5-SMC6 complex component	gene	biological_process-&-1&-GO:2001022-&&-positive regulation of response to DNA damage stimulus-%%-GO:0006310-&&-DNA recombination-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0000781-&&-chromosome, telomeric region-%%-GO:0030915-&&-Smc5-Smc6 complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NSMCE4A				NSMCE4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSMCE4A	0.347838	0.04444444	10	4	FALSE	NSMCE4A	NSMCE4A	125.2	0	10	0	0.68751641	FALSE	0	NSMCE4A	12044	0.11868446
791032	taxon:9606	2.74775484	7.20E-06	170298	1902	castor zinc finger 1	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:CASZ1				CASZ1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASZ1	0.36393349	0.02222222	10	5	FALSE	CASZ1	CASZ1	208.5	0	10	0	0.70870753	FALSE	0	CASZ1	13138	0.12012724
791088	taxon:9606	2.82259335	3.13E-06	170096	1902	nei like DNA glycosylase 3	gene	biological_process-&-1&-GO:0006289-&&-nucleotide-excision repair-%%-GO:0006284-&&-base-excision repair|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000405-&&-bubble DNA binding-%%-GO:0003684-&&-damaged DNA binding-%%-GO:0019104-&&-DNA N-glycosylase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003906-&&-DNA-(apurinic or apyrimidinic site) lyase activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003690-&&-double-stranded DNA binding	G:9606:NEIL3			KEGG-&-1&-hsa03410-&&-Base excision repair	NEIL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEIL3	0.35428412	0.11111111	10	4	FALSE	NEIL3	NEIL3	164.4	0	10	0	0.69623444	FALSE	0	NEIL3	5254	0.12644564
791103	taxon:9606	3.03040807	4.90E-06	170043	1902	riboflavin kinase	gene	biological_process-&-1&-GO:0033864-&&-positive regulation of NAD(P)H oxidase activity-%%-GO:0006771-&&-riboflavin metabolic process-%%-GO:0009398-&&-FMN biosynthetic process-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0009231-&&-riboflavin biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0008531-&&-riboflavin kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding	G:9606:RFK			KEGG-&-1&-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways	RFK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFK	0.32998856	0.13333333	10	4	FALSE	RFK	RFK	58.1	0	10	0	0.66159866	FALSE	0	RFK	4606	0.11330724
791122	taxon:9606	2.72112809	5.91E-06	169962	1902	zinc finger protein 302	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF302				ZNF302	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF302	0.36749464	0.04444444	10	4	FALSE	ZNF302	ZNF302	270.3	0	10	0	0.71314532	FALSE	0	ZNF302	12024	0.14502421
791129	taxon:9606	2.72160076	5.45E-06	169950	1902	nuclear transport factor 2 like export factor 2	gene	biological_process-&-1&-GO:0051028-&&-mRNA transport-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NXT2			KEGG-&-1&-hsa03008-&&-Ribosome biogenesis in eukaryotes-%%-hsa03013-&&-RNA transport-%%-hsa05164-&&-Influenza A-%%-hsa03015-&&-mRNA surveillance pathway	NXT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NXT2	0.36743082	0.13333333	10	5	FALSE	NXT2	NXT2	235.6	0	10	0	0.71306654	FALSE	0	NXT2	12964	0.12694384
791138	taxon:9606	2.84606901	5.13E-06	169913	1902	sphingomyelin phosphodiesterase 3	gene	biological_process-&-1&-GO:0006685-&&-sphingomyelin catabolic process-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0007049-&&-cell cycle-%%-GO:0030072-&&-peptide hormone secretion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0000137-&&-Golgi cis cisterna-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004767-&&-sphingomyelin phosphodiesterase activity-%%-GO:0046872-&&-metal ion binding	G:9606:SMPD3			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	SMPD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMPD3	0.35136182	0.13333333	10	5	FALSE	SMPD3	SMPD3	161.8	0	10	0	0.69232183	FALSE	0	SMPD3	9674	0.1394987
791327	taxon:9606	2.69276824	9.50E-07	169157	1902	REX4 homolog, 3'-5' exonuclease	gene	biological_process-&-1&-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0004527-&&-exonuclease activity	G:9606:REXO4				REXO4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-REXO4	0.37136505	0.46666667	10	4	FALSE	REXO4	REXO4	371.1	0	10	0	0.71787196	FALSE	0	REXO4	4062	0.18067186
791541	taxon:9606	2.90972113	5.13E-06	168175	1902	zinc finger protein 557	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF557				ZNF557	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF557	0.34367555	0.11111111	10	5	FALSE	ZNF557	ZNF557	105.3	0	10	0	0.68171315	FALSE	0	ZNF557	7400	0.12297773
791545	taxon:9606	2.84480857	7.48E-06	168126	1902	BCL2 like 14	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0012505-&&-endomembrane system-%%-GO:0016020-&&-membrane-%%-GO:0043229-&&-intracellular organelle|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:BCL2L14				BCL2L14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L14	0.3515175	0.11111111	10	4	FALSE	BCL2L14	BCL2L14	147.6	0	10	0	0.6925319	FALSE	0	BCL2L14	8826	0.12641509
791565	taxon:9606	2.93146368	2.57E-05	168001	1902	post-GPI attachment to proteins 1	gene	biological_process-&-1&-GO:0015798-&&-myo-inositol transport-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0015031-&&-protein transport-%%-GO:0021871-&&-forebrain regionalization-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0016255-&&-attachment of GPI anchor to protein|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0042578-&&-phosphoric ester hydrolase activity-%%-GO:0016788-&&-hydrolase activity, acting on ester bonds-%%-GO:0004518-&&-nuclease activity	G:9606:PGAP1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00563-&&-Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	PGAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGAP1	0.34112652	0	10	4	FALSE	PGAP1	PGAP1	84.4	0	10	0	0.67808939	FALSE	0	PGAP1	21028	0.10651341
791569	taxon:9606	2.86497558	2.82E-06	167969	1902	prostaglandin E synthase 2	gene	biological_process-&-1&-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005739-&&-mitochondrion-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016829-&&-lyase activity-%%-GO:0003677-&&-DNA binding-%%-GO:0043295-&&-glutathione binding-%%-GO:0050220-&&-prostaglandin-E synthase activity-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity	G:9606:PTGES2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	PTGES2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGES2	0.34904311	0.07142857	10	4	FALSE	PTGES2	PTGES2	174.125	0	9	0	0.68917074	FALSE	1	PTGES2	6606	0.15856164
791574	taxon:9606	2.86056405	3.70E-06	167949	1902	DBF4 zinc finger B	gene	biological_process-&-1&-GO:0010571-&&-positive regulation of nuclear cell cycle DNA replication-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007049-&&-cell cycle-%%-GO:0010971-&&-positive regulation of G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016235-&&-aggresome-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:DBF4B				DBF4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBF4B	0.34958141	0.11111111	10	4	FALSE	DBF4B	DBF4B	138.5	0	10	0	0.68990599	FALSE	0	DBF4B	5804	0.12165493
791585	taxon:9606	2.61367575	5.25E-06	167920	1902	threonyl-tRNA synthetase 2, mitochondrial (putative)	gene	biological_process-&-1&-GO:0070159-&&-mitochondrial threonyl-tRNA aminoacylation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004829-&&-threonine-tRNA ligase activity-%%-GO:0003674-&&-molecular_function-%%-GO:0002161-&&-aminoacyl-tRNA editing activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:TARS2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	TARS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TARS2	0.38260293	0.28888889	10	4	FALSE	TARS2	TARS2	408.6	0	10	0	0.73105404	FALSE	0	TARS2	15642	0.15974178
791599	taxon:9606	2.95163069	3.59E-06	167874	1902	protein phosphatase 1 regulatory subunit 3B	gene	biological_process-&-1&-GO:0050790-&&-regulation of catalytic activity-%%-GO:0005977-&&-glycogen metabolic process-%%-GO:0005981-&&-regulation of glycogen catabolic process-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0005979-&&-regulation of glycogen biosynthetic process|cellular_component-&-1&-GO:0000164-&&-protein phosphatase type 1 complex-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042587-&&-glycogen granule|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0019899-&&-enzyme binding	G:9606:PPP1R3B			KEGG-&-1&-hsa04910-&&-Insulin signaling pathway-%%-hsa04931-&&-Insulin resistance	PPP1R3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R3B	0.33879577	0.2	10	5	FALSE	PPP1R3B	PPP1R3B	100.7	0	10	0	0.67472822	FALSE	0	PPP1R3B	4502	0.14607558
791601	taxon:9606	2.7444462	8.86E-06	167865	1902	zinc finger CCHC-type containing 6	gene	biological_process-&-1&-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0031123-&&-RNA 3'-end processing|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050265-&&-RNA uridylyltransferase activity	G:9606:ZCCHC6				ZCCHC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZCCHC6	0.36437224	0.06666667	10	4	FALSE	ZCCHC6	ZCCHC6	205.9	0	10	0	0.70925897	FALSE	0	ZCCHC6	13234	0.11566197
791626	taxon:9606	2.70127619	1.80E-06	167748	1902	Cbl proto-oncogene like 1	gene	biological_process-&-1&-GO:0035635-&&-entry of bacterium into host cell-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0016337-&&-single organismal cell-cell adhesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:CBLL1				CBLL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CBLL1	0.37019539	0.2	10	4	FALSE	CBLL1	CBLL1	315.5	0	10	0	0.71645397	FALSE	0	CBLL1	5716	0.15822467
791650	taxon:9606	2.63084922	1.69E-05	167576	1902	sorting nexin family member 27	gene	biological_process-&-1&-GO:0006886-&&-intracellular protein transport-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0001770-&&-establishment of natural killer cell polarity-%%-GO:0007165-&&-signal transduction-%%-GO:0016197-&&-endosomal transport-%%-GO:0008333-&&-endosome to lysosome transport|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0030904-&&-retromer complex-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005768-&&-endosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0071203-&&-WASH complex|molecular_function-&-1&-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding	G:9606:SNX27				SNX27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNX27	0.3801054	0.08888889	10	4	FALSE	SNX27	SNX27	297.2	0	10	0	0.7281918	FALSE	0	SNX27	21062	0.12293996
791662	taxon:9606	2.88388215	2.38E-06	167544	1902	tripartite motif containing 7	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM7				TRIM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM7	0.34675481	0.14285714	10	5	FALSE	TRIM7	TRIM7	181	0	9	0	0.68601964	FALSE	1	TRIM7	5194	0.1785361
791663	taxon:9606	2.66425083	3.92E-06	167542	1902	NUAK family kinase 2	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0042149-&&-cellular response to glucose starvation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:NUAK2				NUAK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUAK2	0.37534004	0.26666667	10	4	FALSE	NUAK2	NUAK2	299.9	0	10	0	0.72262486	FALSE	0	NUAK2	11138	0.13619437
791710	taxon:9606	3.06412478	2.84E-06	167270	1902	transketolase like 2	gene	biological_process-&-1&-GO:0008152-&&-metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004802-&&-transketolase activity-%%-GO:0046872-&&-metal ion binding	G:9606:TKTL2			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00030-&&-Pentose phosphate pathway	TKTL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TKTL2	0.32635747	0.22222222	10	5	FALSE	TKTL2	TKTL2	54.6	0	10	0	0.6559792	FALSE	0	TKTL2	2770	0.14650538
791714	taxon:9606	2.87364109	4.07E-06	167224	1902	sprouty RTK signaling antagonist 4	gene	biological_process-&-1&-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPRY4				SPRY4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRY4	0.34799057	0.25	10	4	FALSE	SPRY4	SPRY4	164.875	0	9	0	0.68772648	FALSE	1	SPRY4	5484	0.15705434
791740	taxon:9606	2.62832834	2.52E-05	167103	1902	trafficking protein particle complex 9	gene	biological_process-&-1&-GO:0021987-&&-cerebral cortex development-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0061024-&&-membrane organization-%%-GO:0048208-&&-COPII vesicle coating-%%-GO:0030182-&&-neuron differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005802-&&-trans-Golgi network-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity	G:9606:TRAPPC9				TRAPPC9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAPPC9	0.38046997	0.11111111	10	4	FALSE	TRAPPC9	TRAPPC9	295.5	0	10	0	0.72861194	FALSE	0	TRAPPC9	25418	0.12239735
791753	taxon:9606	3.03907358	6.50E-07	167036	1902	GON7, KEOPS complex subunit homolog	gene		G:9606:GON7				GON7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GON7	0.32904764	0.46666667	10	5	FALSE	GON7	GON7	54.3	0	10	0	0.6601544	FALSE	0	GON7	1138	0.13958869
791863	taxon:9606	2.81061919	5.60E-06	166579	1902	chromosome 9 open reading frame 3	gene	biological_process-&-1&-GO:0002003-&&-angiotensin maturation-%%-GO:0043171-&&-peptide catabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042277-&&-peptide binding-%%-GO:0008237-&&-metallopeptidase activity	G:9606:C9orf3				C9orf3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C9orf3	0.35579349	0.04444444	10	5	FALSE	C9orf3	C9orf3	167.8	0	10	0	0.69823013	FALSE	0	C9orf3	10598	0.12412769
791876	taxon:9606	2.91476288	3.46E-06	182947	1902	alcohol dehydrogenase 1B (class I), beta polypeptide	gene	biological_process-&-1&-GO:0006069-&&-ethanol oxidation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004024-&&-alcohol dehydrogenase activity, zinc-dependent	G:9606:ADH1B	ADH1B	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00071-&&-Fatty acid degradation	ADH1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADH1B	0.34308108	0	10	5	FALSE	ADH1B	ADH1B	118.625	0	9	0	0.68087285	FALSE	1	ADH1B	4388	0.16135117
791893	taxon:9606	2.70600284	2.88E-05	182919	1902	G protein-coupled receptor kinase 3	gene	biological_process-&-1&-GO:0031623-&&-receptor internalization-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0047696-&&-beta-adrenergic receptor kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:GRK3			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04340-&&-Hedgehog signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04740-&&-Olfactory transduction	GRK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK3	0.36954876	0.17777778	10	4	FALSE	GRK3	GRK3	244.9	0	10	0	0.71566619	FALSE	0	GRK3	32300	0.12210579
791929	taxon:9606	2.63384276	2.31E-06	166479	1902	peptidylprolyl isomerase like 4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:PPIL4				PPIL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPIL4	0.37967339	0.26666667	10	4	FALSE	PPIL4	PPIL4	371	0	10	0	0.72769287	FALSE	0	PPIL4	7368	0.15232033
792005	taxon:9606	2.81172207	7.59E-06	166359	1902	Cdk5 and Abl enzyme substrate 1	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CABLES1				CABLES1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CABLES1	0.35565393	0.22222222	10	4	FALSE	CABLES1	CABLES1	174.7	0	10	0	0.69804632	FALSE	0	CABLES1	9324	0.12674419
792131	taxon:9606	2.92122262	8.71E-06	182547	1902	acid phosphatase 5, tartrate resistant	gene	biological_process-&-1&-GO:0006771-&&-riboflavin metabolic process-%%-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0008199-&&-ferric iron binding-%%-GO:0008198-&&-ferrous iron binding-%%-GO:0003993-&&-acid phosphatase activity	G:9606:ACP5			KEGG-&-1&-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04142-&&-Lysosome-%%-hsa05323-&&-Rheumatoid arthritis	ACP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACP5	0.34232242	0.02222222	10	5	FALSE	ACP5	ACP5	85.6	0	10	0	0.67979623	FALSE	0	ACP5	9192	0.11012987
792157	taxon:9606	2.85520718	6.58E-06	166120	1902	StAR related lipid transfer domain containing 13	gene	biological_process-&-1&-GO:0043542-&&-endothelial cell migration-%%-GO:0090051-&&-negative regulation of cell migration involved in sprouting angiogenesis-%%-GO:0097498-&&-endothelial tube lumen extension-%%-GO:0007165-&&-signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005811-&&-lipid particle-%%-GO:0031966-&&-mitochondrial membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:STARD13				STARD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STARD13	0.35023728	0.11111111	10	5	FALSE	STARD13	STARD13	140.6	0	10	0	0.6907988	FALSE	0	STARD13	9256	0.12754545
792218	taxon:9606	3.05545927	2.24E-06	182393	1902	antioxidant 1 copper chaperone	gene	biological_process-&-1&-GO:0006979-&&-response to oxidative stress-%%-GO:0035434-&&-copper ion transmembrane transport-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0006825-&&-copper ion transport-%%-GO:0006878-&&-cellular copper ion homeostasis-%%-GO:0015680-&&-intracellular copper ion transport|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0032767-&&-copper-dependent protein binding-%%-GO:0016530-&&-metallochaperone activity-%%-GO:0016531-&&-copper chaperone activity-%%-GO:0051117-&&-ATPase binding-%%-GO:0005375-&&-copper ion transmembrane transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005507-&&-copper ion binding	G:9606:ATOX1	ATOX1	TRUE	KEGG-&-1&-hsa04978-&&-Mineral absorption	ATOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATOX1	0.32728304	0.25	10	5	FALSE	ATOX1	ATOX1	64	0	9	0	0.65742345	FALSE	1	ATOX1	2082	0.16483161
792221	taxon:9606	2.74271309	1.35E-05	166011	1902	RAS like family 10 member B	gene	biological_process-&-1&-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0003050-&&-regulation of systemic arterial blood pressure by atrial natriuretic peptide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005525-&&-GTP binding	G:9606:RASL10B				RASL10B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RASL10B	0.36460248	0.04444444	10	5	FALSE	RASL10B	RASL10B	207.4	0	10	0	0.70954782	FALSE	0	RASL10B	14934	0.12144536
792328	taxon:9606	2.73893178	2.12E-06	182216	1902	RCC1 and BTB domain containing protein 2	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity|molecular_function-&-1&-GO:0005087-&&-Ran guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:RCBTB2				RCBTB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCBTB2	0.36510584	0.25	10	4	FALSE	RCBTB2	RCBTB2	291.125	0	9	0	0.71017804	FALSE	1	RCBTB2	4896	0.16177697
792332	taxon:9606	2.94784938	1.65E-06	182215	1902	choline O-acetyltransferase	gene	biological_process-&-1&-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0007269-&&-neurotransmitter secretion-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0098793-&&-presynapse-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004102-&&-choline O-acetyltransferase activity	G:9606:CHAT			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04725-&&-Cholinergic synapse	CHAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHAT	0.33923036	0.11111111	10	4	FALSE	CHAT	CHAT	92.1	0	10	0	0.67535844	FALSE	0	CHAT	3044	0.15480607
792341	taxon:9606	2.890657	2.48E-06	182197	1902	chimerin 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0050770-&&-regulation of axonogenesis-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046875-&&-ephrin receptor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:CHN1	CHN1	TRUE		CHN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHN1	0.34594212	0.08888889	10	4	FALSE	CHN1	CHN1	110.2	0	10	0	0.6848905	FALSE	0	CHN1	4048	0.1215708
792343	taxon:9606	2.83125886	3.45E-06	182196	1902	chimerin 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:CHN2	CHN2	TRUE		CHN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHN2	0.35319978	0.11111111	10	4	FALSE	CHN2	CHN2	143.9	0	10	0	0.69479019	FALSE	0	CHN2	6266	0.11946755
792366	taxon:9606	2.91775642	6.22E-06	182151	1902	chloride voltage-gated channel 3	gene	biological_process-&-1&-GO:0006885-&&-regulation of pH-%%-GO:1903959-&&-regulation of anion transmembrane transport-%%-GO:0048388-&&-endosomal lumen acidification-%%-GO:0045794-&&-negative regulation of cell volume-%%-GO:0006810-&&-transport-%%-GO:1902476-&&-chloride transmembrane transport|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0009986-&&-cell surface-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0005770-&&-late endosome-%%-GO:0042581-&&-specific granule-%%-GO:0016021-&&-integral component of membrane-%%-GO:0012506-&&-vesicle membrane-%%-GO:0005769-&&-early endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0030141-&&-secretory granule-%%-GO:0016020-&&-membrane-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045335-&&-phagocytic vesicle-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005247-&&-voltage-gated chloride channel activity-%%-GO:0015297-&&-antiporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005254-&&-chloride channel activity-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0072320-&&-volume-sensitive chloride channel activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:CLCN3				CLCN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLCN3	0.34272909	0.21428571	10	4	FALSE	CLCN3	CLCN3	115.5	0	9	0	0.68037393	FALSE	1	CLCN3	8116	0.14158477
792382	taxon:9606	2.85331653	5.81E-06	165728	1902	inositol hexakisphosphate kinase 3	gene	biological_process-&-1&-GO:0032958-&&-inositol phosphate biosynthetic process-%%-GO:0046488-&&-phosphatidylinositol metabolic process-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0052723-&&-inositol hexakisphosphate 1-kinase activity-%%-GO:0052724-&&-inositol hexakisphosphate 3-kinase activity-%%-GO:0052836-&&-inositol 5-diphosphate pentakisphosphate 5-kinase activity-%%-GO:0052839-&&-inositol diphosphate tetrakisphosphate kinase activity-%%-GO:0000828-&&-inositol hexakisphosphate kinase activity-%%-GO:0008440-&&-inositol-1,4,5-trisphosphate 3-kinase activity-%%-GO:0000829-&&-inositol heptakisphosphate kinase activity-%%-GO:0000827-&&-inositol-1,3,4,5,6-pentakisphosphate kinase activity-%%-GO:0000831-&&-inositol hexakisphosphate 6-kinase activity-%%-GO:0000832-&&-inositol hexakisphosphate 5-kinase activity	G:9606:IP6K3			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system	IP6K3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IP6K3	0.35046935	0.15555556	10	4	FALSE	IP6K3	IP6K3	138.5	0	10	0	0.69111391	FALSE	0	IP6K3	6648	0.12808156
792383	taxon:9606	2.81912715	1.34E-04	182115	1902	complement C3d receptor 2	gene	biological_process-&-1&-GO:0042100-&&-B cell proliferation-%%-GO:0045087-&&-innate immune response-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006955-&&-immune response-%%-GO:0002430-&&-complement receptor mediated signaling pathway-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0006958-&&-complement activation, classical pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001848-&&-complement binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004875-&&-complement receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:CR2			KEGG-&-1&-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04610-&&-Complement and coagulation cascades	CR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CR2	0.35471972	0.10714286	10	4	FALSE	CR2	CR2	208.25	0	9	0	0.69681214	FALSE	1	CR2	172296	0.15032562
792409	taxon:9606	2.92169529	1.66E-06	182065	1902	colony stimulating factor 2 receptor alpha subunit	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0004896-&&-cytokine receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0004872-&&-receptor activity	G:9606:CSF2RA			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CSF2RA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSF2RA	0.34226704	0.21428571	10	5	FALSE	CSF2RA	CSF2RA	127.875	0	9	0	0.67971745	FALSE	1	CSF2RA	3340	0.17176985
792512	taxon:9606	2.81660627	1.03E-05	181877	1902	solute carrier family 25 member 20	gene	biological_process-&-1&-GO:1902603-&&-carnitine transmembrane transport-%%-GO:1902616-&&-acyl carnitine transmembrane transport-%%-GO:0006839-&&-mitochondrial transport-%%-GO:0015879-&&-carnitine transport-%%-GO:0006853-&&-carnitine shuttle|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005476-&&-carnitine:acyl carnitine antiporter activity-%%-GO:0015227-&&-acyl carnitine transmembrane transporter activity-%%-GO:0015226-&&-carnitine transmembrane transporter activity	G:9606:SLC25A20			KEGG-&-1&-hsa04714-&&-Thermogenesis	SLC25A20	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC25A20	0.3550372	0.13333333	10	5	FALSE	SLC25A20	SLC25A20	171.6	0	10	0	0.69723229	FALSE	0	SLC25A20	11108	0.13016717
792517	taxon:9606	2.91239956	4.13E-06	165477	1902	nitric oxide synthase trafficking	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006897-&&-endocytosis-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005856-&&-cytoskeleton-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030666-&&-endocytic vesicle membrane|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:NOSTRIN				NOSTRIN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOSTRIN	0.34335948	0.06666667	10	4	FALSE	NOSTRIN	NOSTRIN	102.3	0	10	0	0.68126674	FALSE	0	NOSTRIN	5956	0.12518428
792528	taxon:9606	2.83377974	8.19E-06	181851	1902	calcium modulating ligand	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0016032-&&-viral process-%%-GO:0001881-&&-receptor recycling|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050839-&&-cell adhesion molecule binding	G:9606:CAMLG				CAMLG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMLG	0.35288558	0.02222222	10	4	FALSE	CAMLG	CAMLG	171	0	10	0	0.69437004	FALSE	0	CAMLG	15150	0.13422713
792569	taxon:9606	2.85378919	3.65E-06	181798	1902	cholecystokinin B receptor	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0048732-&&-gland development-%%-GO:0001696-&&-gastric acid secretion-%%-GO:0038188-&&-cholecystokinin signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0008283-&&-cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0048565-&&-digestive tract development-%%-GO:0007600-&&-sensory perception-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007631-&&-feeding behavior-%%-GO:0007586-&&-digestion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0031741-&&-type B gastrin/cholecystokinin receptor binding-%%-GO:0015054-&&-gastrin receptor activity-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0004951-&&-cholecystokinin receptor activity-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity	G:9606:CCKBR			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CCKBR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCKBR	0.35041131	0.32142857	10	4	FALSE	CCKBR	CCKBR	210.125	0	9	0	0.69103513	FALSE	1	CCKBR	5074	0.1882287
792604	taxon:9606	2.76729163	8.42E-06	181734	1902	dual specificity phosphatase 7	gene	biological_process-&-1&-GO:0043407-&&-negative regulation of MAP kinase activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:DUSP7			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP7	0.36136415	0.15555556	10	4	FALSE	DUSP7	DUSP7	204.5	0	10	0	0.70545139	FALSE	0	DUSP7	11212	0.12876972
792625	taxon:9606	2.7231763	9.55E-06	181699	1902	sphingosine-1-phosphate receptor 1	gene	biological_process-&-1&-GO:0030335-&&-positive regulation of cell migration-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0007420-&&-brain development-%%-GO:0001525-&&-angiogenesis-%%-GO:0016477-&&-cell migration-%%-GO:0030182-&&-neuron differentiation-%%-GO:0001955-&&-blood vessel maturation-%%-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050927-&&-positive regulation of positive chemotaxis-%%-GO:0003245-&&-cardiac muscle tissue growth involved in heart morphogenesis-%%-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0003376-&&-sphingosine-1-phosphate signaling pathway-%%-GO:0007155-&&-cell adhesion-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0061384-&&-heart trabecula morphogenesis-%%-GO:0072678-&&-T cell migration-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0006935-&&-chemotaxis-%%-GO:0030032-&&-lamellipodium assembly-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045446-&&-endothelial cell differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005768-&&-endosome-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0045121-&&-membrane raft-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0046625-&&-sphingolipid binding-%%-GO:0038036-&&-sphingosine-1-phosphate receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:S1PR1			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	S1PR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-S1PR1	0.36721824	0.11111111	10	4	FALSE	S1PR1	S1PR1	218.7	0	10	0	0.71280395	FALSE	0	S1PR1	14022	0.12072968
792668	taxon:9606	2.78793131	1.06E-05	181594	1902	defender against cell death 1	gene	biological_process-&-1&-GO:0001824-&&-blastocyst development-%%-GO:0006915-&&-apoptotic process-%%-GO:0018279-&&-protein N-linked glycosylation via asparagine-%%-GO:0007584-&&-response to nutrient-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0006486-&&-protein glycosylation-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0008250-&&-oligosaccharyltransferase complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004579-&&-dolichyl-diphosphooligosaccharide-protein glycotransferase activity-%%-GO:0004576-&&-oligosaccharyl transferase activity	G:9606:DAD1			KEGG-&-1&-hsa00510-&&-N-Glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	DAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DAD1	0.3586889	0.04444444	10	4	FALSE	DAD1	DAD1	230.6	0	10	0	0.70201145	FALSE	0	DAD1	15978	0.15003262
792691	taxon:9606	2.88608792	3.63E-05	181558	1902	aldo-keto reductase family 1 member C1	gene	biological_process-&-1&-GO:0046683-&&-response to organophosphorus-%%-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0042574-&&-retinal metabolic process-%%-GO:0071395-&&-cellular response to jasmonic acid stimulus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0030299-&&-intestinal cholesterol absorption-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0007586-&&-digestion-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0008206-&&-bile acid metabolic process-%%-GO:0042448-&&-progesterone metabolic process-%%-GO:0044598-&&-doxorubicin metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0047086-&&-ketosteroid monooxygenase activity-%%-GO:0047006-&&-17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity-%%-GO:0047042-&&-androsterone dehydrogenase (B-specific) activity-%%-GO:0005515-&&-protein binding-%%-GO:0032052-&&-bile acid binding-%%-GO:0004032-&&-alditol:NADP+ 1-oxidoreductase activity-%%-GO:0031406-&&-carboxylic acid binding-%%-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0018636-&&-phenanthrene 9,10-monooxygenase activity-%%-GO:0047115-&&-trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity-%%-GO:0047718-&&-indanol dehydrogenase activity	G:9606:AKR1C1	AKR1C1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00140-&&-Steroid hormone biosynthesis	AKR1C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1C1	0.34648979	0.07142857	10	4	FALSE	AKR1C1	AKR1C1	129.125	0	9	0	0.68565201	FALSE	1	AKR1C1	28896	0.13343718
792721	taxon:9606	2.91003624	2.10E-07	148734	1902	testis specific protein, Y-linked 10	gene	biological_process-&-1&-GO:0007506-&&-gonadal mesoderm development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:TSPY10				TSPY10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPY10	0.34363833	0.67857143	10	5	FALSE	TSPY10	TSPY10	131.375	0	9	0	0.68166063	FALSE	1	TSPY10	878	0.16380923
792752	taxon:9606	2.97542146	8.81E-06	181439	1902	ferredoxin 1	gene	biological_process-&-1&-GO:0042446-&&-hormone biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0016125-&&-sterol metabolic process-%%-GO:0006700-&&-C21-steroid hormone biosynthetic process-%%-GO:1904322-&&-cellular response to forskolin-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0044281-&&-small molecule metabolic process-%%-GO:0071320-&&-cellular response to cAMP|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0009055-&&-electron carrier activity-%%-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0005506-&&-iron ion binding	G:9606:FDX1				FDX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FDX1	0.33608684	0.03571429	10	5	FALSE	FDX1	FDX1	75.25	0	9	0	0.67076309	FALSE	1	FDX1	9506	0.15050505
792764	taxon:9606	2.75515992	6.97E-06	181414	1902	fibroblast growth factor 12	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0050905-&&-neuromuscular process-%%-GO:0007507-&&-heart development-%%-GO:0010765-&&-positive regulation of sodium ion transport-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:2000649-&&-regulation of sodium ion transmembrane transporter activity-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:1905150-&&-regulation of voltage-gated sodium channel activity-%%-GO:0003254-&&-regulation of membrane depolarization-%%-GO:2001258-&&-negative regulation of cation channel activity-%%-GO:1902305-&&-regulation of sodium ion transmembrane transport-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0098908-&&-regulation of neuronal action potential|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0017080-&&-sodium channel regulator activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding	G:9606:FGF12				FGF12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGF12	0.36295534	0.17777778	10	5	FALSE	FGF12	FGF12	227.5	0	10	0	0.70747335	FALSE	0	FGF12	10638	0.1328271
792910	taxon:9606	3.0100835	2.65E-05	181170	1902	frizzled class receptor 2	gene	biological_process-&-1&-GO:0030182-&&-neuron differentiation-%%-GO:0060022-&&-hard palate development-%%-GO:0060119-&&-inner ear receptor cell development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0003150-&&-muscular septum morphogenesis-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0030825-&&-positive regulation of cGMP metabolic process-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:FZD2			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	FZD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FZD2	0.3322167	0.02222222	10	4	FALSE	FZD2	FZD2	49.6	0	10	0	0.66498608	FALSE	0	FZD2	18104	0.10917226
792916	taxon:9606	2.87238065	4.10E-06	181157	1902	gamma-aminobutyric acid type A receptor alpha1 subunit	gene	biological_process-&-1&-GO:0060078-&&-regulation of postsynaptic membrane potential-%%-GO:0051932-&&-synaptic transmission, GABAergic-%%-GO:0006810-&&-transport-%%-GO:0071420-&&-cellular response to histamine-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1902476-&&-chloride transmembrane transport|cellular_component-&-1&-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0034707-&&-chloride channel complex-%%-GO:1902710-&&-GABA receptor complex-%%-GO:1902711-&&-GABA-A receptor complex|molecular_function-&-1&-GO:0022851-&&-GABA-gated chloride ion channel activity-%%-GO:1904315-&&-transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential-%%-GO:0004890-&&-GABA-A receptor activity-%%-GO:0008144-&&-drug binding-%%-GO:0016917-&&-GABA receptor activity	G:9606:GABRA1	GABRA1	TRUE	KEGG-&-1&-hsa05032-&&-Morphine addiction-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa05033-&&-Nicotine addiction-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GABRA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABRA1	0.34814327	0.22222222	10	4	FALSE	GABRA1	GABRA1	128.1	0	10	0	0.68793656	FALSE	0	GABRA1	5082	0.1305102
792923	taxon:9606	3.02268788	3.61E-06	164752	1902	glucosamine-6-phosphate deaminase 2	gene	biological_process-&-1&-GO:0006006-&&-glucose metabolic process-%%-GO:0006044-&&-N-acetylglucosamine metabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004342-&&-glucosamine-6-phosphate deaminase activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:GNPDA2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	GNPDA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNPDA2	0.33083138	0.2	10	4	FALSE	GNPDA2	GNPDA2	64	0	10	0	0.66288535	FALSE	0	GNPDA2	3914	0.12349515
792950	taxon:9606	2.7096266	1.82E-06	181093	1902	membrane spanning 4-domains A2	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0032998-&&-Fc-epsilon receptor I complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0019863-&&-IgE binding	G:9606:MS4A2			KEGG-&-1&-hsa05310-&&-Asthma-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway	MS4A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MS4A2	0.36905454	0.44444444	10	5	FALSE	MS4A2	MS4A2	267.6	0	10	0	0.71506223	FALSE	0	MS4A2	5520	0.14010471
792963	taxon:9606	3.09595084	4.71E-06	181077	1902	vascular endothelial growth factor D	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0002576-&&-platelet degranulation-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0008283-&&-cell proliferation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0050918-&&-positive chemotaxis|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005172-&&-vascular endothelial growth factor receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0043185-&&-vascular endothelial growth factor receptor 3 binding	G:9606:VEGFD			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway	VEGFD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VEGFD	0.32300254	0.07142857	10	4	FALSE	VEGFD	VEGFD	37.375	0	9	0	0.65067486	FALSE	1	VEGFD	3902	0.14237452
792999	taxon:9606	2.86213959	1.76E-06	181016	1902	FosB proto-oncogene, AP-1 transcription factor subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0043278-&&-response to morphine-%%-GO:0051412-&&-response to corticosterone-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding	G:9606:FOSB			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa05030-&&-Cocaine addiction-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05031-&&-Amphetamine addiction	FOSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOSB	0.34938897	0.46666667	10	4	FALSE	FOSB	FOSB	174.9	0	10	0	0.6896434	FALSE	0	FOSB	3758	0.16185185
793047	taxon:9606	2.89018434	2.63E-05	180843	1902	C-X-C motif chemokine ligand 2	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006935-&&-chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0045236-&&-CXCR chemokine receptor binding	G:9606:CXCL2	CXCL2	TRUE	KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa05134-&&-Legionellosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL2	0.34599869	0.03571429	10	4	FALSE	CXCL2	CXCL2	126	0	9	0	0.68496928	FALSE	1	CXCL2	23608	0.13282078
793104	taxon:9606	3.02694186	1.28E-05	180724	1902	glucagon	gene	biological_process-&-1&-GO:0010737-&&-protein kinase A signaling-%%-GO:0035948-&&-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007165-&&-signal transduction-%%-GO:1900118-&&-negative regulation of execution phase of apoptosis-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0051571-&&-positive regulation of histone H3-K4 methylation-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007631-&&-feeding behavior-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0090280-&&-positive regulation of calcium ion import-%%-GO:0008283-&&-cell proliferation-%%-GO:0032092-&&-positive regulation of protein binding|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:GCG	GCG	TRUE	KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GCG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCG	0.33036644	0.07142857	10	5	FALSE	GCG	GCG	56.625	0	9	0	0.66217636	FALSE	1	GCG	10250	0.13331354
793119	taxon:9606	2.94170474	4.59E-05	180693	1902	gamma-glutamyl carboxylase	gene	biological_process-&-1&-GO:0006464-&&-cellular protein modification process-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008488-&&-gamma-glutamyl carboxylase activity	G:9606:GGCX			KEGG-&-1&-hsa00130-&&-Ubiquinone and other terpenoid-quinone biosynthesis-%%-hsa01100-&&-Metabolic pathways	GGCX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GGCX	0.33993894	0.08888889	10	5	FALSE	GGCX	GGCX	94.1	0	10	0	0.67638254	FALSE	0	GGCX	48126	0.11050767
793136	taxon:9606	2.72601229	1.89E-05	180671	1902	gap junction protein beta 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0051259-&&-protein oligomerization-%%-GO:0055085-&&-transmembrane transport-%%-GO:0015868-&&-purine ribonucleotide transport-%%-GO:0016264-&&-gap junction assembly-%%-GO:0006810-&&-transport-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005922-&&-connexin complex-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0005243-&&-gap junction channel activity-%%-GO:0042803-&&-protein homodimerization activity	G:9606:GJB1				GJB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJB1	0.3668362	0.22222222	10	5	FALSE	GJB1	GJB1	226.4	0	10	0	0.71233129	FALSE	0	GJB1	19144	0.12420417
793164	taxon:9606	2.79864503	1.11E-05	180608	1902	G protein subunit alpha transducin 2	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0006457-&&-protein folding-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007601-&&-visual perception-%%-GO:0007223-&&-Wnt signaling pathway, calcium modulating pathway-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0001580-&&-detection of chemical stimulus involved in sensory perception of bitter taste-%%-GO:0007602-&&-phototransduction-%%-GO:0046549-&&-retinal cone cell development-%%-GO:0050908-&&-detection of light stimulus involved in visual perception-%%-GO:0009642-&&-response to light intensity|cellular_component-&-1&-GO:0001917-&&-photoreceptor inner segment-%%-GO:0005886-&&-plasma membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0042622-&&-photoreceptor outer segment membrane-%%-GO:0001750-&&-photoreceptor outer segment|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0008020-&&-G-protein coupled photoreceptor activity-%%-GO:0005525-&&-GTP binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding	G:9606:GNAT2			KEGG-&-1&-hsa04744-&&-Phototransduction	GNAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNAT2	0.35731577	0.08888889	10	4	FALSE	GNAT2	GNAT2	160.3	0	10	0	0.70022583	FALSE	0	GNAT2	16264	0.11174004
793193	taxon:9606	2.84008193	4.10E-05	164165	1902	ADP ribosylation factor like GTPase 6 interacting protein 6	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:ARL6IP6				ARL6IP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARL6IP6	0.35210252	0.04444444	10	4	FALSE	ARL6IP6	ARL6IP6	139.6	0	10	0	0.69331968	FALSE	0	ARL6IP6	33516	0.10826189
793267	taxon:9606	2.92626438	8.16E-06	180402	1902	glucuronidase beta	gene	biological_process-&-1&-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006027-&&-glycosaminoglycan catabolic process|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0004566-&&-beta-glucuronidase activity	G:9606:GUSB			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa04142-&&-Lysosome-%%-hsa00531-&&-Glycosaminoglycan degradation	GUSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUSB	0.34173262	0.07142857	10	4	FALSE	GUSB	GUSB	116.25	0	9	0	0.67895594	FALSE	1	GUSB	8130	0.13847305
793298	taxon:9606	2.68032141	8.06E-06	180353	1902	hemoglobin subunit gamma 1	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005833-&&-hemoglobin complex|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0020037-&&-heme binding	G:9606:HBG1				HBG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBG1	0.37308958	0.22222222	10	4	FALSE	HBG1	HBG1	344.6	0	10	0	0.71994643	FALSE	0	HBG1	24494	0.16123596
793339	taxon:9606	2.7976997	2.46E-06	180286	1902	major histocompatibility complex, class II, DR beta 5	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0042613-&&-MHC class II protein complex-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane|molecular_function-&-1&-GO:0042605-&&-peptide antigen binding	G:9606:HLA-DRB5			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05310-&&-Asthma-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05323-&&-Rheumatoid arthritis	HLA-DRB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-DRB5	0.3574365	0.28888889	10	4	FALSE	HLA-DRB5	HLA-DRB5	194.4	0	10	0	0.70038338	FALSE	0	HLA-DRB5	4854	0.1370945
793355	taxon:9606	3.0779896	4.43E-06	180250	1902	forkhead box A2	gene	biological_process-&-1&-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0033132-&&-negative regulation of glucokinase activity-%%-GO:0070741-&&-response to interleukin-6-%%-GO:0000432-&&-positive regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0001708-&&-cell fate specification-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:2000543-&&-positive regulation of gastrulation-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:2000049-&&-positive regulation of cell-cell adhesion mediated by cadherin-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0000433-&&-negative regulation of transcription from RNA polymerase II promoter by glucose-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0090009-&&-primitive streak formation-%%-GO:2000971-&&-negative regulation of detection of glucose-%%-GO:0040019-&&-positive regulation of embryonic development|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding	G:9606:FOXA2			KEGG-&-1&-hsa04950-&&-Maturity onset diabetes of the young-%%-hsa04213-&&-Longevity regulating pathway - multiple species	FOXA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXA2	0.32488739	0	10	5	FALSE	FOXA2	FOXA2	40.6	0	10	0	0.6536684	FALSE	0	FOXA2	4050	0.12184615
787024	taxon:9606	2.76098944	3.07E-05	180213	1902	inter-alpha-trypsin inhibitor heavy chain 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030212-&&-hyaluronan metabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity	G:9606:ITIH2				ITIH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITIH2	0.362189	0.14285714	9	5	FALSE	ITIH2	ITIH2	269.5714286	0	8	0	0.70650176	FALSE	1	ITIH2	25484	0.16263603
787039	taxon:9606	2.86859934	2.82E-06	180186	1902	homeobox B6	gene	biological_process-&-1&-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0034101-&&-erythrocyte homeostasis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXB6				HOXB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB6	0.34860219	0.22222222	9	5	FALSE	HOXB6	HOXB6	160.1111111	0	9	0	0.68856678	FALSE	0	HOXB6	4166	0.15429122
787041	taxon:9606	2.79344572	2.93E-06	180179	1902	homeobox C6	gene	biological_process-&-1&-GO:0048706-&&-embryonic skeletal system development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXC6				HOXC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXC6	0.35798082	0.16666667	9	5	FALSE	HOXC6	HOXC6	189.5555556	0	9	0	0.70109238	FALSE	0	HOXC6	5634	0.12906158
787044	taxon:9606	2.82180558	3.11E-06	163786	1902	dyslexia susceptibility 1 candidate 1	gene	biological_process-&-1&-GO:0007368-&&-determination of left/right symmetry-%%-GO:0036158-&&-outer dynein arm assembly-%%-GO:0033146-&&-regulation of intracellular estrogen receptor signaling pathway-%%-GO:0001764-&&-neuron migration-%%-GO:0036159-&&-inner dynein arm assembly-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0003341-&&-cilium movement|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0097730-&&-non-motile cilium-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0030331-&&-estrogen receptor binding-%%-GO:0005515-&&-protein binding	G:9606:DYX1C1				DYX1C1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYX1C1	0.35438303	0.25	9	4	FALSE	DYX1C1	DYX1C1	185.3333333	0	9	0	0.69636574	FALSE	0	DYX1C1	6022	0.13989594
787047	taxon:9606	2.89412321	4.72E-06	163783	1902	sprouty related EVH1 domain containing 1	gene	biological_process-&-1&-GO:0010801-&&-negative regulation of peptidyl-threonine phosphorylation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0010923-&&-negative regulation of phosphatase activity-%%-GO:0043517-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:0090311-&&-regulation of protein deacetylation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0019902-&&-phosphatase binding-%%-GO:0030291-&&-protein serine/threonine kinase inhibitor activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005173-&&-stem cell factor receptor binding	G:9606:SPRED1				SPRED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRED1	0.34552779	0	9	5	FALSE	SPRED1	SPRED1	121.2222222	0	9	0	0.6843128	FALSE	0	SPRED1	5888	0.13358025
787147	taxon:9606	2.91649598	1.05E-05	179984	1902	lipase E, hormone sensitive type	gene	biological_process-&-1&-GO:0019433-&&-triglyceride catabolic process-%%-GO:0042758-&&-long-chain fatty acid catabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0046340-&&-diacylglycerol catabolic process-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005811-&&-lipid particle-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0033878-&&-hormone-sensitive lipase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0004806-&&-triglyceride lipase activity-%%-GO:0005515-&&-protein binding	G:9606:LIPE	LIPE	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04371-&&-Apelin signaling pathway	LIPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIPE	0.34287721	0.05555556	9	4	FALSE	LIPE	LIPE	114.8888889	0	9	0	0.680584	FALSE	0	LIPE	9716	0.14550602
787169	taxon:9606	2.91113912	6.50E-07	179935	1902	leukocyte receptor tyrosine kinase	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:LTK				LTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTK	0.34350815	0.25	9	5	FALSE	LTK	LTK	144	0	9	0	0.68147681	FALSE	0	LTK	1628	0.17671177
787215	taxon:9606	2.82196313	2.61E-06	179854	1902	MYC associated zinc finger protein	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006369-&&-termination of RNA polymerase II transcription|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:MAZ				MAZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAZ	0.35436324	0.13888889	9	4	FALSE	MAZ	MAZ	182.5555556	0	9	0	0.69633948	FALSE	0	MAZ	6196	0.13834092
787381	taxon:9606	2.71356546	2.00E-06	179526	1902	myosin light chain 1	gene	biological_process-&-1&-GO:0030049-&&-muscle filament sliding-%%-GO:0006936-&&-muscle contraction-%%-GO:0060048-&&-cardiac muscle contraction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030017-&&-sarcomere-%%-GO:0005859-&&-muscle myosin complex-%%-GO:0030016-&&-myofibril|molecular_function-&-1&-GO:0008307-&&-structural constituent of muscle-%%-GO:0005509-&&-calcium ion binding	G:9606:MYL1				MYL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL1	0.36851884	0.19444444	9	5	FALSE	MYL1	MYL1	314.6666667	0	9	0	0.71440576	FALSE	0	MYL1	6442	0.16420075
787460	taxon:9606	2.91933197	2.69E-06	163009	1902	NUT midline carcinoma family member 1	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NUTM1				NUTM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NUTM1	0.34254412	0.05555556	9	5	FALSE	NUTM1	NUTM1	109.5555556	0	9	0	0.68011134	FALSE	0	NUTM1	4400	0.13377013
787466	taxon:9606	3.03907358	1.07E-05	179390	1902	microfibrillar associated protein 3	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:MFAP3				MFAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MFAP3	0.32904764	0.05555556	9	4	FALSE	MFAP3	MFAP3	68.55555556	0	9	0	0.6601544	FALSE	0	MFAP3	8836	0.13259549
787474	taxon:9606	3.37088388	2.00E-05	179360	1902	C-X-C motif chemokine ligand 9	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0030816-&&-positive regulation of cAMP metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0006968-&&-cellular defense response-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0051607-&&-defense response to virus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0006952-&&-defense response-%%-GO:0006954-&&-inflammatory response-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0006955-&&-immune response-%%-GO:0006935-&&-chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0048248-&&-CXCR3 chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:CXCL9			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL9	0.2966581	0.02777778	9	5	FALSE	CXCL9	CXCL9	17.22222222	0	9	0	0.60485269	FALSE	0	CXCL9	13240	0.12747631
787521	taxon:9606	2.7778478	1.22E-06	162897	1902	ribosomal protein L22 like 1	gene	biological_process-&-1&-GO:0002181-&&-cytoplasmic translation|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit|molecular_function-&-1&-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL22L1			KEGG-&-1&-hsa03010-&&-Ribosome	RPL22L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL22L1	0.35999093	0.13888889	9	4	FALSE	RPL22L1	RPL22L1	272.8888889	0	9	0	0.70369203	FALSE	0	RPL22L1	3866	0.17034722
787597	taxon:9606	2.9056247	1.65E-06	179123	1902	nuclear factor of activated T-cells 3	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1902894-&&-negative regulation of pri-miRNA transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:NFATC3			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04662-&&-B cell receptor signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04360-&&-Axon guidance-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway	NFATC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFATC3	0.34416007	0.16666667	9	5	FALSE	NFATC3	NFATC3	126.3333333	0	9	0	0.68239588	FALSE	0	NFATC3	3322	0.14249843
787638	taxon:9606	2.85772806	2.13E-05	179041	1902	natriuretic peptide A	gene	biological_process-&-1&-GO:1903815-&&-negative regulation of collecting lymphatic vessel constriction-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:1903766-&&-positive regulation of potassium ion export across plasma membrane-%%-GO:0003085-&&-negative regulation of systemic arterial blood pressure-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0032868-&&-response to insulin-%%-GO:0050880-&&-regulation of blood vessel size-%%-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060452-&&-positive regulation of cardiac muscle contraction-%%-GO:1901841-&&-regulation of high voltage-gated calcium channel activity-%%-GO:1902261-&&-positive regulation of delayed rectifier potassium channel activity-%%-GO:0007168-&&-receptor guanylyl cyclase signaling pathway-%%-GO:0007565-&&-female pregnancy-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:0035994-&&-response to muscle stretch-%%-GO:0014898-&&-cardiac muscle hypertrophy in response to stress-%%-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:0060372-&&-regulation of atrial cardiac muscle cell membrane repolarization-%%-GO:1902514-&&-regulation of calcium ion transmembrane transport via high voltage-gated calcium channel|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0042629-&&-mast cell granule|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0071855-&&-neuropeptide receptor binding-%%-GO:0005184-&&-neuropeptide hormone activity-%%-GO:0051428-&&-peptide hormone receptor binding	G:9606:NPPA	NPPA	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa05143-&&-African trypanosomiasis-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04714-&&-Thermogenesis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	NPPA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPPA	0.34992833	0.05555556	9	5	FALSE	NPPA	NPPA	145.4444444	0	9	0	0.69037866	FALSE	0	NPPA	23394	0.13076615
787670	taxon:9606	2.87852529	6.38E-06	162603	1902	testis specific 10 interacting protein	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TSGA10IP				TSGA10IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSGA10IP	0.34740011	0.02777778	9	4	FALSE	TSGA10IP	TSGA10IP	145.5555556	0	9	0	0.68691245	FALSE	0	TSGA10IP	8010	0.13697046
787714	taxon:9606	3.03592248	1.14E-05	178902	1902	plexin A2	gene	biological_process-&-1&-GO:0021785-&&-branchiomotor neuron axon guidance-%%-GO:0051642-&&-centrosome localization-%%-GO:0021935-&&-cerebellar granule cell precursor tangential migration-%%-GO:0071526-&&-semaphorin-plexin signaling pathway-%%-GO:0060174-&&-limb bud formation-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0001756-&&-somitogenesis-%%-GO:0021915-&&-neural tube development-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0048841-&&-regulation of axon extension involved in axon guidance|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0002116-&&-semaphorin receptor complex|molecular_function-&-1&-GO:0017154-&&-semaphorin receptor activity-%%-GO:0005515-&&-protein binding	G:9606:PLXNA2			KEGG-&-1&-hsa04360-&&-Axon guidance	PLXNA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLXNA2	0.32938917	0.02777778	9	4	FALSE	PLXNA2	PLXNA2	52.77777778	0	9	0	0.66067959	FALSE	0	PLXNA2	8916	0.12264151
787725	taxon:9606	2.8739562	2.35E-05	178871	1902	podocalyxin like	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0033634-&&-positive regulation of cell-cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0016477-&&-cell migration-%%-GO:0022408-&&-negative regulation of cell-cell adhesion-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0072175-&&-epithelial tube formation-%%-GO:0072015-&&-glomerular visceral epithelial cell development-%%-GO:0032534-&&-regulation of microvillus assembly|cellular_component-&-1&-GO:0030175-&&-filopodium-%%-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0044297-&&-cell body-%%-GO:0031528-&&-microvillus membrane-%%-GO:0036057-&&-slit diaphragm-%%-GO:0001726-&&-ruffle-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005615-&&-extracellular space-%%-GO:0030027-&&-lamellipodium-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005815-&&-microtubule organizing center|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PODXL				PODXL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PODXL	0.34795241	0.05555556	9	5	FALSE	PODXL	PODXL	140.2222222	0	9	0	0.68767397	FALSE	0	PODXL	24268	0.13114241
787771	taxon:9606	2.93760832	3.94E-06	178804	1902	protein phosphatase 2 regulatory subunit B'beta	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0031952-&&-regulation of protein autophosphorylation-%%-GO:0051388-&&-positive regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0010469-&&-regulation of receptor activity-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0070317-&&-negative regulation of G0 to G1 transition-%%-GO:0031334-&&-positive regulation of protein complex assembly-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0000159-&&-protein phosphatase type 2A complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PPP2R5B			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa03015-&&-mRNA surveillance pathway-%%-hsa05165-&&-Human papillomavirus infection	PPP2R5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP2R5B	0.34041298	0.27777778	9	5	FALSE	PPP2R5B	PPP2R5B	95.22222222	0	9	0	0.67706528	FALSE	0	PPP2R5B	4236	0.13982705
787804	taxon:9606	2.72097054	6.28E-06	178766	1902	cAMP-dependent protein kinase inhibitor alpha	gene	biological_process-&-1&-GO:0010389-&&-regulation of G2/M transition of mitotic cell cycle-%%-GO:2000480-&&-negative regulation of cAMP-dependent protein kinase activity-%%-GO:0042308-&&-negative regulation of protein import into nucleus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004862-&&-cAMP-dependent protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0034236-&&-protein kinase A catalytic subunit binding	G:9606:PKIA	PKIA	TRUE	KEGG-&-1&-hsa05034-&&-Alcoholism	PKIA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKIA	0.36751592	0.27777778	9	4	FALSE	PKIA	PKIA	251.3333333	0	9	0	0.71317158	FALSE	0	PKIA	8226	0.13334513
787850	taxon:9606	2.78541043	6.36E-06	178723	1902	protein kinase, X-linked	gene	biological_process-&-1&-GO:0001525-&&-angiogenesis-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0030334-&&-regulation of cell migration-%%-GO:2000696-&&-regulation of epithelial cell differentiation involved in kidney development-%%-GO:0007155-&&-cell adhesion-%%-GO:0060562-&&-epithelial tube morphogenesis-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0060993-&&-kidney morphogenesis-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0030099-&&-myeloid cell differentiation-%%-GO:0031589-&&-cell-substrate adhesion-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004691-&&-cAMP-dependent protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PRKX				PRKX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKX	0.35901352	0.22222222	9	4	FALSE	PRKX	PRKX	218.2222222	0	9	0	0.70243159	FALSE	0	PRKX	7854	0.14024564
787935	taxon:9606	3.00567197	1.31E-05	178563	1902	orosomucoid 1	gene	biological_process-&-1&-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006953-&&-acute-phase response-%%-GO:0002682-&&-regulation of immune system process-%%-GO:0006954-&&-inflammatory response-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0035580-&&-specific granule lumen|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ORM1				ORM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ORM1	0.3327043	0.02777778	9	4	FALSE	ORM1	ORM1	58.33333333	0	9	0	0.66572134	FALSE	0	ORM1	11644	0.12790123
788095	taxon:9606	3.04096424	1.39E-06	178251	1902	phosphoglycerate kinase 2	gene	biological_process-&-1&-GO:0030317-&&-flagellated sperm motility-%%-GO:0016310-&&-phosphorylation-%%-GO:0006096-&&-glycolytic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0035686-&&-sperm fibrous sheath-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004618-&&-phosphoglycerate kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:PGK2			KEGG-&-1&-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis	PGK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGK2	0.32884307	0.25	9	5	FALSE	PGK2	PGK2	67.44444444	0	9	0	0.65983929	FALSE	0	PGK2	1816	0.15978836
788258	taxon:9606	3.01307704	2.90E-06	177988	1902	G protein-coupled receptor kinase 1	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0016056-&&-rhodopsin mediated signaling pathway-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0097381-&&-photoreceptor disc membrane|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0050254-&&-rhodopsin kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity	G:9606:GRK1			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04744-&&-Phototransduction-%%-hsa04062-&&-Chemokine signaling pathway	GRK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK1	0.33188663	0.14285714	9	5	FALSE	GRK1	GRK1	68	0	8	0	0.66448716	FALSE	1	GRK1	2604	0.16050221
788298	taxon:9606	2.84559634	2.20E-06	177932	1902	ras responsive element binding protein 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903691-&&-positive regulation of wound healing, spreading of epidermal cells-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:0033601-&&-positive regulation of mammary gland epithelial cell proliferation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0001650-&&-fibrillar center-%%-GO:0016607-&&-nuclear speck-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:RREB1				RREB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RREB1	0.35142019	0.44444444	9	5	FALSE	RREB1	RREB1	219.7777778	0	9	0	0.69240061	FALSE	0	RREB1	3404	0.1841909
788347	taxon:9606	3.50118166	6.67E-06	177835	1902	C-C motif chemokine ligand 8	gene	biological_process-&-1&-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0009615-&&-response to virus-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0006816-&&-calcium ion transport-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0006887-&&-exocytosis-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0045663-&&-positive regulation of myoblast differentiation-%%-GO:0002548-&&-monocyte chemotaxis|cellular_component-&-1&-GO:0005623-&&-cell-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0048020-&&-CCR chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0016004-&&-phospholipase activator activity-%%-GO:0008201-&&-heparin binding-%%-GO:0004672-&&-protein kinase activity	G:9606:CCL8			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL8	0.28561786	0.02777778	9	5	FALSE	CCL8	CCL8	17.11111111	0	9	0	0.58313639	FALSE	0	CCL8	8386	0.18148148
788351	taxon:9606	3.02363321	1.90E-05	177824	1902	C-C motif chemokine ligand 21	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:2000147-&&-positive regulation of cell motility-%%-GO:0030838-&&-positive regulation of actin filament polymerization-%%-GO:0060326-&&-cell chemotaxis-%%-GO:2000529-&&-positive regulation of myeloid dendritic cell chemotaxis-%%-GO:1903237-&&-negative regulation of leukocyte tethering or rolling-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:2000548-&&-negative regulation of dendritic cell dendrite assembly-%%-GO:0031529-&&-ruffle organization-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001768-&&-establishment of T cell polarity-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0048469-&&-cell maturation-%%-GO:0006954-&&-inflammatory response-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:2000107-&&-negative regulation of leukocyte apoptotic process-%%-GO:0033630-&&-positive regulation of cell adhesion mediated by integrin-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0010560-&&-positive regulation of glycoprotein biosynthetic process-%%-GO:0097026-&&-dendritic cell dendrite assembly-%%-GO:0043552-&&-positive regulation of phosphatidylinositol 3-kinase activity-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0006955-&&-immune response-%%-GO:0050921-&&-positive regulation of chemotaxis-%%-GO:0002606-&&-positive regulation of dendritic cell antigen processing and presentation-%%-GO:0034695-&&-response to prostaglandin E-%%-GO:0035759-&&-mesangial cell-matrix adhesion-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0051491-&&-positive regulation of filopodium assembly-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0031295-&&-T cell costimulation-%%-GO:0031274-&&-positive regulation of pseudopodium assembly-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005623-&&-cell-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0048020-&&-CCR chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0042379-&&-chemokine receptor binding-%%-GO:0031732-&&-CCR7 chemokine receptor binding	G:9606:CCL21			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04064-&&-NF-kappa B signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL21	0.33072795	0.05555556	9	5	FALSE	CCL21	CCL21	57.55555556	0	9	0	0.6627278	FALSE	0	CCL21	14374	0.1223176
788519	taxon:9606	3.02237277	3.76E-06	177512	1902	Sp4 transcription factor	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:SP4				SP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP4	0.33086587	0.11111111	9	5	FALSE	SP4	SP4	60	0	9	0	0.66293787	FALSE	0	SP4	3324	0.13722478
788524	taxon:9606	2.88624547	5.80E-06	177504	1902	spastin	gene	biological_process-&-1&-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0051013-&&-microtubule severing-%%-GO:0000281-&&-mitotic cytokinesis-%%-GO:0090148-&&-membrane fission-%%-GO:0001578-&&-microtubule bundle formation-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0010458-&&-exit from mitosis-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0031468-&&-nuclear envelope reassembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0051228-&&-mitotic spindle disassembly-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0034214-&&-protein hexamerization-%%-GO:0008152-&&-metabolic process-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030496-&&-midbody-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005768-&&-endosome-%%-GO:0005874-&&-microtubule-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005819-&&-spindle-%%-GO:0005737-&&-cytoplasm-%%-GO:1904115-&&-axon cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005811-&&-lipid particle-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0008568-&&-microtubule-severing ATPase activity-%%-GO:0005524-&&-ATP binding	G:9606:SPAST				SPAST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPAST	0.34647088	0.08333333	9	4	FALSE	SPAST	SPAST	125	0	9	0	0.68562575	FALSE	0	SPAST	6964	0.12880616
788588	taxon:9606	2.72900583	1.43E-06	177388	1902	tubulin folding cofactor E	gene	biological_process-&-1&-GO:0008344-&&-adult locomotory behavior-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0006457-&&-protein folding-%%-GO:0009791-&&-post-embryonic development-%%-GO:0014889-&&-muscle atrophy-%%-GO:0007023-&&-post-chaperonin tubulin folding pathway-%%-GO:0007052-&&-mitotic spindle organization-%%-GO:0048589-&&-developmental growth-%%-GO:0048936-&&-peripheral nervous system neuron axonogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0051087-&&-chaperone binding	G:9606:TBCE	TBCE	TRUE		TBCE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBCE	0.36643381	0.16666667	9	4	FALSE	TBCE	TBCE	267.6666667	0	9	0	0.71183236	FALSE	0	TBCE	4164	0.14409722
788619	taxon:9606	2.80069324	6.30E-06	177293	1902	telomerase associated protein 1	gene	biological_process-&-1&-GO:0000722-&&-telomere maintenance via recombination-%%-GO:0006278-&&-RNA-dependent DNA biosynthetic process-%%-GO:0008380-&&-RNA splicing|cellular_component-&-1&-GO:0071011-&&-precatalytic spliceosome-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0005737-&&-cytoplasm-%%-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005682-&&-U5 snRNP-%%-GO:0005697-&&-telomerase holoenzyme complex|molecular_function-&-1&-GO:0003720-&&-telomerase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0002039-&&-p53 binding-%%-GO:0070034-&&-telomerase RNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0019899-&&-enzyme binding	G:9606:TEP1				TEP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEP1	0.35705446	0.22222222	9	4	FALSE	TEP1	TEP1	187.2222222	0	9	0	0.69988446	FALSE	0	TEP1	7652	0.13121396
788628	taxon:9606	2.74948795	5.63E-06	177284	1902	transcription factor AP-2 beta	gene	biological_process-&-1&-GO:0097276-&&-cellular creatinine homeostasis-%%-GO:0006915-&&-apoptotic process-%%-GO:0097277-&&-cellular urea homeostasis-%%-GO:0043588-&&-skin development-%%-GO:0055078-&&-sodium ion homeostasis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0097070-&&-ductus arteriosus closure-%%-GO:0010226-&&-response to lithium ion-%%-GO:0030510-&&-regulation of BMP signaling pathway-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0048485-&&-sympathetic nervous system development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0010842-&&-retina layer formation-%%-GO:0072017-&&-distal tubule development-%%-GO:0097275-&&-cellular ammonia homeostasis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0035137-&&-hindlimb morphogenesis-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0010960-&&-magnesium ion homeostasis-%%-GO:0055075-&&-potassium ion homeostasis-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0001822-&&-kidney development-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0042493-&&-response to drug-%%-GO:0072044-&&-collecting duct development-%%-GO:0072210-&&-metanephric nephron development-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0055062-&&-phosphate ion homeostasis-%%-GO:0055074-&&-calcium ion homeostasis-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0035136-&&-forelimb morphogenesis-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043027-&&-cysteine-type endopeptidase inhibitor activity involved in apoptotic process-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0001158-&&-enhancer sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001106-&&-RNA polymerase II transcription corepressor activity-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0000983-&&-transcription factor activity, RNA polymerase II core promoter sequence-specific-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:TFAP2B				TFAP2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFAP2B	0.36370409	0.33333333	9	4	FALSE	TFAP2B	TFAP2B	270.7777778	0	9	0	0.70841868	FALSE	0	TFAP2B	8192	0.15037037
788796	taxon:9606	3.15550654	5.97E-06	160482	1902	C-type lectin domain family 18 member A	gene	cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0030247-&&-polysaccharide binding-%%-GO:0005515-&&-protein binding	G:9606:CLEC18A				CLEC18A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLEC18A	0.31690633	0	9	5	FALSE	CLEC18A	CLEC18A	64.66666667	0	9	0	0.64074891	FALSE	0	CLEC18A	5960	0.20340788
788871	taxon:9606	2.82842288	1.79E-06	176720	1902	transient receptor potential cation channel subfamily V member 1	gene	biological_process-&-1&-GO:0051209-&&-release of sequestered calcium ion into cytosol-%%-GO:1901594-&&-response to capsazepine-%%-GO:0050954-&&-sensory perception of mechanical stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0001660-&&-fever generation-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:0050955-&&-thermoception-%%-GO:0050968-&&-detection of chemical stimulus involved in sensory perception of pain-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0060454-&&-positive regulation of gastric acid secretion-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0048266-&&-behavioral response to pain-%%-GO:0050960-&&-detection of temperature stimulus involved in thermoception-%%-GO:1990035-&&-calcium ion import into cell-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0071468-&&-cellular response to acidic pH-%%-GO:0002790-&&-peptide secretion-%%-GO:0014047-&&-glutamate secretion-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0060083-&&-smooth muscle contraction involved in micturition-%%-GO:0007635-&&-chemosensory behavior-%%-GO:0090212-&&-negative regulation of establishment of blood-brain barrier-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0034605-&&-cellular response to heat-%%-GO:0050965-&&-detection of temperature stimulus involved in sensory perception of pain-%%-GO:0071502-&&-cellular response to temperature stimulus-%%-GO:0001774-&&-microglial cell activation-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071318-&&-cellular response to ATP-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0032591-&&-dendritic spine membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0051219-&&-phosphoprotein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005262-&&-calcium channel activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0015278-&&-calcium-release channel activity-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0005231-&&-excitatory extracellular ligand-gated ion channel activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0005230-&&-extracellular ligand-gated ion channel activity-%%-GO:0097603-&&-temperature-gated ion channel activity	G:9606:TRPV1	TRPV1	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	TRPV1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRPV1	0.35355392	0.23809524	9	5	FALSE	TRPV1	TRPV1	215.1428571	0	8	0	0.69526285	FALSE	1	TRPV1	3570	0.17079264
788967	taxon:9606	2.81597605	2.17E-06	176512	1902	Zic family member 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0001947-&&-heart looping-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0035469-&&-determination of pancreatic left/right asymmetry-%%-GO:0035545-&&-determination of left/right asymmetry in nervous system-%%-GO:0071910-&&-determination of liver left/right asymmetry-%%-GO:0071907-&&-determination of digestive tract left/right asymmetry-%%-GO:0030324-&&-lung development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZIC3			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	ZIC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZIC3	0.35511666	0.22222222	9	4	FALSE	ZIC3	ZIC3	239.8888889	0	9	0	0.69733732	FALSE	0	ZIC3	6558	0.17596672
788985	taxon:9606	2.86954467	6.71E-06	176456	1902	ADAM metallopeptidase domain 12	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007155-&&-cell adhesion-%%-GO:0007520-&&-myoblast fusion|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0017124-&&-SH3 domain binding	G:9606:ADAM12				ADAM12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAM12	0.34848734	0.11111111	9	5	FALSE	ADAM12	ADAM12	157.2222222	0	9	0	0.68840922	FALSE	0	ADAM12	7810	0.15921409
789168	taxon:9606	2.80825587	3.14E-06	176059	1902	Fc fragment of IgG receptor IIc (gene/pseudogene)	gene	biological_process-&-1&-GO:0006955-&&-immune response-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0019864-&&-IgG binding	G:9606:FCGR2C			KEGG-&-1&-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05150-&&-Staphylococcus aureus infection	FCGR2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCGR2C	0.35609291	0.47222222	9	5	FALSE	FCGR2C	FCGR2C	257.5555556	0	9	0	0.69862402	FALSE	0	FCGR2C	5436	0.18772271
789219	taxon:9606	2.76508587	1.75E-06	175975	1902	cell division cycle 14A	gene	biological_process-&-1&-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:0060271-&&-cilium assembly-%%-GO:0051301-&&-cell division-%%-GO:0051256-&&-mitotic spindle midzone assembly-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007096-&&-regulation of exit from mitosis-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0072686-&&-mitotic spindle-%%-GO:0005813-&&-centrosome-%%-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0060091-&&-kinocilium-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity	G:9606:CDC14A			KEGG-&-1&-hsa04110-&&-Cell cycle	CDC14A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDC14A	0.36165242	0.27777778	9	4	FALSE	CDC14A	CDC14A	243.6666667	0	9	0	0.70581902	FALSE	0	CDC14A	4358	0.147923
789242	taxon:9606	2.84071215	1.24E-06	175911	1902	eukaryotic translation initiation factor 4E binding protein 3	gene	biological_process-&-1&-GO:0045947-&&-negative regulation of translational initiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016281-&&-eukaryotic translation initiation factor 4F complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0030371-&&-translation repressor activity-%%-GO:0005515-&&-protein binding-%%-GO:0008190-&&-eukaryotic initiation factor 4E binding	G:9606:EIF4EBP3			KEGG-&-1&-hsa03013-&&-RNA transport	EIF4EBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF4EBP3	0.3520244	0	9	5	FALSE	EIF4EBP3	EIF4EBP3	197.6666667	0	9	0	0.69321464	FALSE	0	EIF4EBP3	3556	0.15733333
789364	taxon:9606	2.95714511	3.33E-06	175656	1902	mitogen-activated protein kinase kinase kinase 13	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0007254-&&-JNK cascade-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0008385-&&-IkappaB kinase complex|molecular_function-&-1&-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:MAP3K13			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP3K13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K13	0.33816399	0.0952381	9	5	FALSE	MAP3K13	MAP3K13	86	0	8	0	0.67380915	FALSE	1	MAP3K13	3038	0.16145553
789365	taxon:9606	2.75232393	7.28E-06	175653	1902	oncostatin M receptor	gene	biological_process-&-1&-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0038165-&&-oncostatin-M-mediated signaling pathway-%%-GO:0034097-&&-response to cytokine-%%-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005900-&&-oncostatin-M receptor complex-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0004924-&&-oncostatin-M receptor activity-%%-GO:0019838-&&-growth factor binding	G:9606:OSMR			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	OSMR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OSMR	0.36332933	0.33333333	9	4	FALSE	OSMR	OSMR	244.6666667	0	9	0	0.70794601	FALSE	0	OSMR	8346	0.1459162
789486	taxon:9606	2.87427131	5.60E-06	175362	1902	regulator of G-protein signaling 6	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RGS6				RGS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS6	0.34791427	0.08333333	9	5	FALSE	RGS6	RGS6	137.3333333	0	9	0	0.68762145	FALSE	0	RGS6	6410	0.13473316
789517	taxon:9606	2.82275091	5.11E-06	175288	1902	RUN and cysteine rich domain containing beclin 1 interacting protein	gene	biological_process-&-1&-GO:1901097-&&-negative regulation of autophagosome maturation-%%-GO:0002376-&&-immune system process-%%-GO:0043553-&&-negative regulation of phosphatidylinositol 3-kinase activity-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0006909-&&-phagocytosis-%%-GO:0006914-&&-autophagy-%%-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0071985-&&-multivesicular body sorting pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0005764-&&-lysosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RUBCN			KEGG-&-1&-hsa04140-&&-Autophagy - animal	RUBCN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RUBCN	0.35426434	0.36111111	9	5	FALSE	RUBCN	RUBCN	169.1111111	0	9	0	0.69620818	FALSE	0	RUBCN	5974	0.12890923
789559	taxon:9606	2.81392784	8.40E-07	175185	1902	Rho guanine nucleotide exchange factor 17	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:ARHGEF17				ARHGEF17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF17	0.35537514	0.38095238	9	4	FALSE	ARHGEF17	ARHGEF17	272.4285714	0	8	0	0.69767869	FALSE	1	ARHGEF17	3206	0.19659618
789628	taxon:9606	2.804317	9.59E-06	175031	1902	acyl-CoA thioesterase 8	gene	biological_process-&-1&-GO:0033540-&&-fatty acid beta-oxidation using acyl-CoA oxidase-%%-GO:0006637-&&-acyl-CoA metabolic process-%%-GO:0009062-&&-fatty acid catabolic process-%%-GO:0045225-&&-negative regulation of CD4 biosynthetic process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0016032-&&-viral process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0016559-&&-peroxisome fission-%%-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0043649-&&-dicarboxylic acid catabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005782-&&-peroxisomal matrix|molecular_function-&-1&-GO:0052815-&&-medium-chain acyl-CoA hydrolase activity-%%-GO:0052689-&&-carboxylic ester hydrolase activity-%%-GO:0003986-&&-acetyl-CoA hydrolase activity-%%-GO:0016289-&&-CoA hydrolase activity-%%-GO:0005515-&&-protein binding-%%-GO:0033882-&&-choloyl-CoA hydrolase activity-%%-GO:0016290-&&-palmitoyl-CoA hydrolase activity-%%-GO:0047617-&&-acyl-CoA hydrolase activity-%%-GO:0052816-&&-long-chain acyl-CoA hydrolase activity-%%-GO:0005102-&&-receptor binding	G:9606:ACOT8			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis	ACOT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACOT8	0.35659307	0.02777778	9	4	FALSE	ACOT8	ACOT8	193.6666667	0	9	0	0.6992805	FALSE	0	ACOT8	10042	0.13555087
789737	taxon:9606	2.81802426	1.95E-06	174792	1902	SH2 domain containing 3A	gene	biological_process-&-1&-GO:0009967-&&-positive regulation of signal transduction-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007254-&&-JNK cascade-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding	G:9606:SH2D3A				SH2D3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D3A	0.35485855	0.23809524	9	5	FALSE	SH2D3A	SH2D3A	235.8571429	0	8	0	0.69699596	FALSE	1	SH2D3A	3084	0.17886973
789794	taxon:9606	3.00157555	7.24E-06	174653	1902	regulator of calcineurin 2	gene	biological_process-&-1&-GO:0070884-&&-regulation of calcineurin-NFAT signaling cascade-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:0019722-&&-calcium-mediated signaling|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0008597-&&-calcium-dependent protein serine/threonine phosphatase regulator activity-%%-GO:0003676-&&-nucleic acid binding	G:9606:RCAN2			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	RCAN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RCAN2	0.33315836	0.19444444	9	5	FALSE	RCAN2	RCAN2	69.11111111	0	9	0	0.66640408	FALSE	0	RCAN2	5600	0.13402508
789811	taxon:9606	2.83645817	1.90E-06	174606	1902	CWC27 spliceosome associated protein homolog	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0071013-&&-catalytic step 2 spliceosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity	G:9606:CWC27				CWC27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CWC27	0.35255235	0.11111111	9	5	FALSE	CWC27	CWC27	182.3333333	0	9	0	0.69392364	FALSE	0	CWC27	3432	0.14736842
789936	taxon:9606	2.92626438	4.75E-06	174312	1902	ret finger protein like 2	gene	molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:RFPL2				RFPL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFPL2	0.34173262	0.08333333	9	5	FALSE	RFPL2	RFPL2	103.1111111	0	9	0	0.67895594	FALSE	0	RFPL2	5282	0.13061917
789950	taxon:9606	2.80163857	6.14E-06	174265	1902	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	gene	biological_process-&-1&-GO:0009396-&&-folic acid-containing compound biosynthetic process-%%-GO:0046655-&&-folic acid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0046653-&&-tetrahydrofolate metabolic process-%%-GO:0006730-&&-one-carbon metabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005615-&&-extracellular space-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0042301-&&-phosphate ion binding-%%-GO:0004487-&&-methylenetetrahydrofolate dehydrogenase (NAD+) activity-%%-GO:0004488-&&-methylenetetrahydrofolate dehydrogenase (NADP+) activity-%%-GO:0004477-&&-methenyltetrahydrofolate cyclohydrolase activity	G:9606:MTHFD2			KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01100-&&-Metabolic pathways	MTHFD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFD2	0.35693398	0.13888889	9	5	FALSE	MTHFD2	MTHFD2	219.5555556	0	9	0	0.69972691	FALSE	0	MTHFD2	9114	0.15033128
790003	taxon:9606	2.87001733	4.31E-06	174142	1902	DAZ interacting zinc finger protein 1	gene	biological_process-&-1&-GO:0007281-&&-germ cell development-%%-GO:0007283-&&-spermatogenesis-%%-GO:0045184-&&-establishment of protein localization-%%-GO:0051220-&&-cytoplasmic sequestering of protein-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0007275-&&-multicellular organism development-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0097539-&&-ciliary transition fiber-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005634-&&-nucleus-%%-GO:0005814-&&-centriole|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:DZIP1				DZIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DZIP1	0.34842995	0.30555556	9	4	FALSE	DZIP1	DZIP1	139.7777778	0	9	0	0.68833044	FALSE	0	DZIP1	5486	0.13586252
790229	taxon:9606	2.83519773	4.24E-06	173576	1902	zinc finger CCCH-type containing 7B	gene	biological_process-&-1&-GO:0016032-&&-viral process|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZC3H7B				ZC3H7B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZC3H7B	0.35270909	0.08333333	9	5	FALSE	ZC3H7B	ZC3H7B	163.1111111	0	9	0	0.69413371	FALSE	0	ZC3H7B	7662	0.12848868
790277	taxon:9606	2.8788404	8.91E-06	173459	1902	neuronal calcium sensor 1	gene	biological_process-&-1&-GO:0010975-&&-regulation of neuron projection development-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0045921-&&-positive regulation of exocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0031045-&&-dense core granule-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030424-&&-axon-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005245-&&-voltage-gated calcium channel activity-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:NCS1				NCS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCS1	0.34736208	0.05555556	9	5	FALSE	NCS1	NCS1	129.6666667	0	9	0	0.68685993	FALSE	0	NCS1	9550	0.12181303
790344	taxon:9606	2.88577281	2.58E-06	173264	1902	HIG1 hypoxia inducible domain family member 1A	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070469-&&-respiratory chain-%%-GO:0043234-&&-protein complex-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane	G:9606:HIGD1A				HIGD1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIGD1A	0.34652763	0.02777778	9	4	FALSE	HIGD1A	HIGD1A	138.4444444	0	9	0	0.68570453	FALSE	0	HIGD1A	4690	0.1344401
790434	taxon:9606	2.96880416	7.09E-06	173002	1902	regulator of G-protein signaling 17	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0043005-&&-neuron projection-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RGS17				RGS17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS17	0.33683596	0.05555556	9	4	FALSE	RGS17	RGS17	82.88888889	0	9	0	0.67186597	FALSE	0	RGS17	6044	0.12747631
790496	taxon:9606	2.7910824	1.99E-06	172690	1902	F-box and leucine rich repeat protein 3	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0043153-&&-entrainment of circadian clock by photoperiod-%%-GO:0031648-&&-protein destabilization-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0031146-&&-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0042752-&&-regulation of circadian rhythm-%%-GO:0048511-&&-rhythmic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016604-&&-nuclear body-%%-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005634-&&-nucleus-%%-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXL3			KEGG-&-1&-hsa04710-&&-Circadian rhythm	FBXL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL3	0.35828394	0.44444444	9	4	FALSE	FBXL3	FBXL3	266.1111111	0	9	0	0.70148627	FALSE	0	FBXL3	3844	0.17340287
790587	taxon:9606	2.83220419	2.14E-06	172067	1902	eukaryotic translation initiation factor 2 alpha kinase 1	gene	biological_process-&-1&-GO:0046501-&&-protoporphyrinogen IX metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0010999-&&-regulation of eIF2 alpha phosphorylation by heme-%%-GO:0009605-&&-response to external stimulus-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0045993-&&-negative regulation of translational initiation by iron-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0010998-&&-regulation of translational initiation by eIF2 alpha phosphorylation-%%-GO:0006909-&&-phagocytosis-%%-GO:0006950-&&-response to stress-%%-GO:0030225-&&-macrophage differentiation-%%-GO:0046986-&&-negative regulation of hemoglobin biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004694-&&-eukaryotic translation initiation factor 2alpha kinase activity-%%-GO:0020037-&&-heme binding	G:9606:EIF2AK1			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05164-&&-Influenza A-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	EIF2AK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EIF2AK1	0.35308189	0.19047619	9	4	FALSE	EIF2AK1	EIF2AK1	224.5714286	0	8	0	0.69463263	FALSE	1	EIF2AK1	4410	0.18017915
790632	taxon:9606	2.72585473	1.15E-05	171704	1902	inositol hexakisphosphate kinase 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0006817-&&-phosphate ion transport-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0052836-&&-inositol 5-diphosphate pentakisphosphate 5-kinase activity-%%-GO:0052839-&&-inositol diphosphate tetrakisphosphate kinase activity-%%-GO:0000828-&&-inositol hexakisphosphate kinase activity-%%-GO:0008440-&&-inositol-1,4,5-trisphosphate 3-kinase activity-%%-GO:0000829-&&-inositol heptakisphosphate kinase activity-%%-GO:0000827-&&-inositol-1,3,4,5,6-pentakisphosphate kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0000832-&&-inositol hexakisphosphate 5-kinase activity-%%-GO:0052723-&&-inositol hexakisphosphate 1-kinase activity-%%-GO:0052724-&&-inositol hexakisphosphate 3-kinase activity	G:9606:IP6K2			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system	IP6K2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IP6K2	0.36685741	0.13888889	9	4	FALSE	IP6K2	IP6K2	260.1111111	0	9	0	0.71235754	FALSE	0	IP6K2	14384	0.1420496
790655	taxon:9606	2.9021585	4.15E-06	171620	1902	zinc finger HIT-type containing 6	gene	biological_process-&-1&-GO:0000492-&&-box C/D snoRNP assembly-%%-GO:0042254-&&-ribosome biogenesis-%%-GO:0048254-&&-snoRNA localization-%%-GO:0051259-&&-protein oligomerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0070761-&&-pre-snoRNP complex|molecular_function-&-1&-GO:0001094-&&-TFIID-class transcription factor binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:ZNHIT6				ZNHIT6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNHIT6	0.34457112	0	9	4	FALSE	ZNHIT6	ZNHIT6	160.4285714	0	8	0	0.68297358	FALSE	1	ZNHIT6	5342	0.1688862
790757	taxon:9606	2.57759571	3.43E-06	171318	1902	debranching RNA lariats 1	gene	biological_process-&-1&-GO:0000375-&&-RNA splicing, via transesterification reactions-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0008419-&&-RNA lariat debranching enzyme activity	G:9606:DBR1				DBR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DBR1	0.38795844	0.30555556	9	4	FALSE	DBR1	DBR1	478.2222222	0	9	0	0.73706738	FALSE	0	DBR1	8712	0.17335428
790776	taxon:9606	2.94832204	1.02E-05	171251	1902	membrane associated ring-CH-type finger 2	gene	biological_process-&-1&-GO:0006897-&&-endocytosis-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0010008-&&-endosome membrane-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:MARCH2				2-Mar	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCH2	0.33917597	0.02777778	9	5	FALSE	2-Mar	2-Mar	96.55555556	0	9	0	0.67527966	FALSE	0	2-Mar	9324	0.12890683
790827	taxon:9606	2.99590358	3.22E-06	171059	1902	taste 2 receptor member 7	gene	biological_process-&-1&-GO:0001580-&&-detection of chemical stimulus involved in sensory perception of bitter taste-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0008527-&&-taste receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0033038-&&-bitter taste receptor activity	G:9606:TAS2R7			KEGG-&-1&-hsa04742-&&-Taste transduction	TAS2R7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAS2R7	0.33378911	0.02777778	9	5	FALSE	TAS2R7	TAS2R7	70	0	9	0	0.6673494	FALSE	0	TAS2R7	3844	0.13185185
790862	taxon:9606	2.82180558	2.27E-06	170856	1902	Ras and Rab interactor 2	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0061024-&&-membrane organization-%%-GO:0006897-&&-endocytosis-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0030695-&&-GTPase regulator activity-%%-GO:0005096-&&-GTPase activator activity	G:9606:RIN2				RIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIN2	0.35438303	0.0952381	9	4	FALSE	RIN2	RIN2	226.2857143	0	8	0	0.69636574	FALSE	1	RIN2	4988	0.17549118
790909	taxon:9606	2.98534741	5.31E-05	170720	1902	atypical chemokine receptor 4	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006955-&&-immune response-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0055037-&&-recycling endosome|molecular_function-&-1&-GO:0004950-&&-chemokine receptor activity-%%-GO:0019956-&&-chemokine binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding	G:9606:ACKR4			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	ACKR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACKR4	0.33496939	0.02777778	9	5	FALSE	ACKR4	ACKR4	79.55555556	0	9	0	0.66910877	FALSE	0	ACKR4	71574	0.12063978
790967	taxon:9606	2.78257444	4.47E-06	170567	1902	F-box protein 34	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBXO34				FBXO34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO34	0.35937942	0.16666667	9	5	FALSE	FBXO34	FBXO34	224.5555556	0	9	0	0.70290426	FALSE	0	FBXO34	10150	0.14512765
790970	taxon:9606	2.88498503	1.19E-05	170563	1902	molybdenum cofactor sulfurase	gene	biological_process-&-1&-GO:0006777-&&-Mo-molybdopterin cofactor biosynthetic process-%%-GO:0043545-&&-molybdopterin cofactor metabolic process-%%-GO:0032324-&&-molybdopterin cofactor biosynthetic process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008265-&&-Mo-molybdopterin cofactor sulfurase activity-%%-GO:0102867-&&-molybdenum cofactor sulfurtransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0030151-&&-molybdenum ion binding-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:MOCOS			KEGG-&-1&-hsa00790-&&-Folate biosynthesis	MOCOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOCOS	0.34662225	0.02777778	9	4	FALSE	MOCOS	MOCOS	115.7777778	0	9	0	0.68583583	FALSE	0	MOCOS	10664	0.11734694
791015	taxon:9606	3.04364267	3.06E-06	170373	1902	GIPC PDZ domain containing family member 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:GIPC2				GIPC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIPC2	0.32855368	0	9	5	FALSE	GIPC2	GIPC2	66	0	8	0	0.65939289	FALSE	1	GIPC2	3186	0.16927083
791056	taxon:9606	2.77312116	3.41E-06	170210	1902	ubiquitin conjugating enzyme E2 Q1	gene	biological_process-&-1&-GO:0061458-&&-reproductive system development-%%-GO:0070459-&&-prolactin secretion-%%-GO:0007617-&&-mating behavior-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0001967-&&-suckling behavior-%%-GO:0007566-&&-embryo implantation-%%-GO:0009566-&&-fertilization|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0030175-&&-filopodium|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0061631-&&-ubiquitin conjugating enzyme activity	G:9606:UBE2Q1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	UBE2Q1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBE2Q1	0.36060451	0.22222222	9	4	FALSE	UBE2Q1	UBE2Q1	223.1111111	0	9	0	0.70447981	FALSE	0	UBE2Q1	6606	0.13857833
791067	taxon:9606	2.87316843	1.94E-06	170156	1902	HECT and RLD domain containing E3 ubiquitin protein ligase family member 6	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:HERC6				HERC6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HERC6	0.34804782	0.33333333	9	4	FALSE	HERC6	HERC6	188.2857143	0	8	0	0.68780526	FALSE	1	HERC6	3342	0.17746062
791236	taxon:9606	2.92484638	4.79E-06	169564	1902	SERTA domain containing 4	gene	cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:SERTAD4				SERTAD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERTAD4	0.3418983	0.58333333	9	5	FALSE	SERTAD4	SERTAD4	122	0	9	0	0.67919227	FALSE	0	SERTAD4	5130	0.16905532
791250	taxon:9606	2.81377029	2.50E-05	169535	1902	DnaJ heat shock protein family (Hsp40) member C12	gene		G:9606:DNAJC12				DNAJC12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC12	0.35539504	0.02777778	9	4	FALSE	DNAJC12	DNAJC12	164.4444444	0	9	0	0.69770495	FALSE	0	DNAJC12	19158	0.12096576
791275	taxon:9606	2.88340948	9.09E-06	169412	1902	component of oligomeric golgi complex 6	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0015031-&&-protein transport-%%-GO:0070085-&&-glycosylation-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0017119-&&-Golgi transport complex-%%-GO:0032588-&&-trans-Golgi network membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COG6				COG6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COG6	0.34681165	0.44444444	9	5	FALSE	COG6	COG6	123.7777778	0	9	0	0.68609842	FALSE	0	COG6	7834	0.11937735
791310	taxon:9606	2.83519773	4.80E-07	169244	1902	matrix extracellular phosphoglycoprotein	gene	biological_process-&-1&-GO:0001501-&&-skeletal system development-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0031214-&&-biomineral tissue development-%%-GO:0046850-&&-regulation of bone remodeling|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:1990430-&&-extracellular matrix protein binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005515-&&-protein binding	G:9606:MEPE				MEPE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEPE	0.35270909	0.72222222	9	4	FALSE	MEPE	MEPE	258.5555556	0	9	0	0.69413371	FALSE	0	MEPE	1338	0.21736286
791324	taxon:9606	2.77406649	3.22E-06	169166	1902	apoptosis and caspase activation inhibitor	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AVEN				AVEN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AVEN	0.36048163	0.22222222	9	4	FALSE	AVEN	AVEN	253.8888889	0	9	0	0.70432225	FALSE	0	AVEN	7802	0.15967855
791339	taxon:9606	2.89853474	1.41E-05	169102	1902	solute carrier family 39 member 10	gene	biological_process-&-1&-GO:1903615-&&-positive regulation of protein tyrosine phosphatase activity-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0071578-&&-zinc II ion transmembrane import-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway-%%-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0002903-&&-negative regulation of B cell apoptotic process|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity	G:9606:SLC39A10				SLC39A10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A10	0.3450019	0	9	4	FALSE	SLC39A10	SLC39A10	137.3333333	0	9	0	0.68357754	FALSE	0	SLC39A10	14570	0.13729439
791347	taxon:9606	2.92295573	3.99E-06	169065	1902	short coiled-coil protein	gene	biological_process-&-1&-GO:0061635-&&-regulation of protein complex stability-%%-GO:0016239-&&-positive regulation of macroautophagy|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005768-&&-endosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SCOC				SCOC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCOC	0.34211945	0.02777778	9	5	FALSE	SCOC	SCOC	99.88888889	0	9	0	0.67950738	FALSE	0	SCOC	4568	0.1278853
791351	taxon:9606	2.6535371	4.28E-06	169051	1902	trafficking protein particle complex 11	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity	G:9606:TRAPPC11				TRAPPC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRAPPC11	0.37685548	0.19047619	9	4	FALSE	TRAPPC11	TRAPPC11	429.2857143	0	8	0	0.72441048	FALSE	1	TRAPPC11	7766	0.18565244
791353	taxon:9606	3.26674019	3.16E-05	169044	1902	brevican	gene	biological_process-&-1&-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0021766-&&-hippocampus development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0030206-&&-chondroitin sulfate biosynthetic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007417-&&-central nervous system development-%%-GO:0030208-&&-dermatan sulfate biosynthetic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0043202-&&-lysosomal lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0005540-&&-hyaluronic acid binding	G:9606:BCAN				BCAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCAN	0.30611556	0.05555556	9	5	FALSE	BCAN	BCAN	24.55555556	0	9	0	0.62220997	FALSE	0	BCAN	29302	0.13714286
791397	taxon:9606	2.82605956	1.76E-06	168811	1902	human immunodeficiency virus type I enhancer binding protein 3	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007275-&&-multicellular organism development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0035914-&&-skeletal muscle cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:HIVEP3				HIVEP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIVEP3	0.35384958	0.27777778	9	4	FALSE	HIVEP3	HIVEP3	183.7777778	0	9	0	0.69565674	FALSE	0	HIVEP3	3294	0.14623142
791416	taxon:9606	2.70931149	4.45E-06	168729	1902	nucleic acid binding protein 1	gene	biological_process-&-1&-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0007093-&&-mitotic cell cycle checkpoint-%%-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006281-&&-DNA repair-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0000724-&&-double-strand break repair via homologous recombination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000784-&&-nuclear chromosome, telomeric region-%%-GO:0005829-&&-cytosol-%%-GO:0070876-&&-SOSS complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:NABP1				NABP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NABP1	0.36909746	0.25	9	4	FALSE	NABP1	NABP1	279.1111111	0	9	0	0.71511475	FALSE	0	NABP1	8282	0.14169629
791508	taxon:9606	2.94343784	8.38E-05	168347	1902	SIL1 nucleotide exchange factor	gene	biological_process-&-1&-GO:0006886-&&-intracellular protein transport-%%-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:SIL1			KEGG-&-1&-hsa04141-&&-Protein processing in endoplasmic reticulum	SIL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIL1	0.33973879	0.08333333	9	5	FALSE	SIL1	SIL1	102.8888889	0	9	0	0.67609369	FALSE	0	SIL1	80822	0.12694479
791519	taxon:9606	2.93130613	2.57E-06	168278	1902	chromosome 22 open reading frame 29	gene	biological_process-&-1&-GO:0051881-&&-regulation of mitochondrial membrane potential-%%-GO:0097345-&&-mitochondrial outer membrane permeabilization|cellular_component-&-1&-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C22orf29				C22orf29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C22orf29	0.34114485	0.41666667	9	4	FALSE	C22orf29	C22orf29	104.4444444	0	9	0	0.67811565	FALSE	0	C22orf29	3590	0.13746157
791520	taxon:9606	2.8008508	1.24E-06	168265	1902	ribosomal oxygenase 1	gene	biological_process-&-1&-GO:0030961-&&-peptidyl-arginine hydroxylation-%%-GO:0070544-&&-histone H3-K36 demethylation-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0034720-&&-histone H3-K4 demethylation|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0051864-&&-histone demethylase activity (H3-K36 specific)-%%-GO:0032453-&&-histone demethylase activity (H3-K4 specific)-%%-GO:0016706-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding	G:9606:RIOX1				RIOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIOX1	0.35703437	0.30555556	9	4	FALSE	RIOX1	RIOX1	243.3333333	0	9	0	0.6998582	FALSE	0	RIOX1	2588	0.16988897
791532	taxon:9606	2.74885773	5.74E-06	168223	1902	small ArfGAP2	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:SMAP2			KEGG-&-1&-hsa04144-&&-Endocytosis	SMAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMAP2	0.36378747	0.11111111	9	4	FALSE	SMAP2	SMAP2	274.4444444	0	9	0	0.70852371	FALSE	0	SMAP2	12782	0.15798911
791582	taxon:9606	2.77012762	8.67E-06	167934	1902	chromodomain helicase DNA binding protein 9	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding	G:9606:CHD9				CHD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHD9	0.3609942	0.13888889	9	4	FALSE	CHD9	CHD9	240.1111111	0	9	0	0.70497873	FALSE	0	CHD9	11296	0.14902286
791624	taxon:9606	2.88309438	2.49E-06	167759	1902	tubulin alpha like 3	gene	biological_process-&-1&-GO:0007017-&&-microtubule-based process-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBAL3			KEGG-&-1&-hsa04540-&&-Gap junction-%%-hsa05130-&&-Pathogenic Escherichia coli infection-%%-hsa04145-&&-Phagosome-%%-hsa04210-&&-Apoptosis-%%-hsa04530-&&-Tight junction	TUBAL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBAL3	0.34684955	0.36111111	9	5	FALSE	TUBAL3	TUBAL3	178.2222222	0	9	0	0.68615094	FALSE	0	TUBAL3	4222	0.17365854
791642	taxon:9606	2.70805105	7.94E-06	167608	1902	F-box protein 38	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus	G:9606:FBXO38				FBXO38	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO38	0.36926926	0.19444444	9	4	FALSE	FBXO38	FBXO38	276.6666667	0	9	0	0.71532483	FALSE	0	FBXO38	12990	0.14220393
791689	taxon:9606	2.94485584	2.17E-06	167426	1902	inter-alpha-trypsin inhibitor heavy chain family member 5	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030212-&&-hyaluronan metabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:ITIH5				ITIH5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITIH5	0.3395752	0.08333333	9	5	FALSE	ITIH5	ITIH5	107.1111111	0	9	0	0.67585736	FALSE	0	ITIH5	4080	0.13892511
791702	taxon:9606	2.83834883	2.80E-06	167314	1902	testis specific serine kinase 1B	gene	biological_process-&-1&-GO:0007286-&&-spermatid development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0031514-&&-motile cilium-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding	G:9606:TSSK1B				TSSK1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSSK1B	0.35231751	0.11111111	9	4	FALSE	TSSK1B	TSSK1B	179.8888889	0	9	0	0.69360853	FALSE	0	TSSK1B	6148	0.15372907
791748	taxon:9606	3.08208602	4.11E-06	167072	1902	potassium two pore domain channel subfamily K member 16	gene	biological_process-&-1&-GO:0006813-&&-potassium ion transport-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005267-&&-potassium channel activity-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005515-&&-protein binding	G:9606:KCNK16				KCNK16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNK16	0.32445558	0.08333333	9	5	FALSE	KCNK16	KCNK16	41.77777778	0	9	0	0.65298566	FALSE	0	KCNK16	3492	0.1393597
791766	taxon:9606	2.77564204	4.64E-06	166961	1902	centrosomal protein 78	gene	biological_process-&-1&-GO:0097711-&&-ciliary basal body docking-%%-GO:0000086-&&-G2/M transition of mitotic cell cycle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005814-&&-centriole-%%-GO:0005813-&&-centrosome	G:9606:CEP78				CEP78	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEP78	0.36027701	0.16666667	9	4	FALSE	CEP78	CEP78	227.8888889	0	9	0	0.70405966	FALSE	0	CEP78	7184	0.14295691
791776	taxon:9606	2.83519773	6.53E-06	166936	1902	Src like adaptor 2	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0050776-&&-regulation of immune response-%%-GO:0050849-&&-negative regulation of calcium-mediated signaling-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0050869-&&-negative regulation of B cell activation-%%-GO:0019724-&&-B cell mediated immunity-%%-GO:0030154-&&-cell differentiation-%%-GO:0042110-&&-T cell activation-%%-GO:0050851-&&-antigen receptor-mediated signaling pathway-%%-GO:0009967-&&-positive regulation of signal transduction|cellular_component-&-1&-GO:0010008-&&-endosome membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:SLA2				SLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLA2	0.35270909	0.36111111	9	4	FALSE	SLA2	SLA2	203.3333333	0	9	0	0.69413371	FALSE	0	SLA2	7178	0.16090437
791789	taxon:9606	2.75484481	1.45E-06	166862	1902	BTB domain containing 10	gene	biological_process-&-1&-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0044342-&&-type B pancreatic cell proliferation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center-%%-GO:0005737-&&-cytoplasm	G:9606:BTBD10				BTBD10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTBD10	0.36299685	0.19444444	9	4	FALSE	BTBD10	BTBD10	250.4444444	0	9	0	0.70752587	FALSE	0	BTBD10	4548	0.14742835
791838	taxon:9606	2.93571766	1.77E-06	182994	1902	alpha-1-B glycoprotein	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0008150-&&-biological_process-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0034774-&&-secretory granule lumen-%%-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:A1BG				A1BG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-A1BG	0.34063221	0.05555556	9	5	FALSE	A1BG	A1BG	138.4444444	0	9	0	0.67738039	FALSE	0	A1BG	4514	0.19531004
791847	taxon:9606	2.87757996	5.60E-06	182980	1902	ATP binding cassette subfamily A member 2	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0055085-&&-transmembrane transport-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0032383-&&-regulation of intracellular cholesterol transport-%%-GO:0042493-&&-response to drug-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006629-&&-lipid metabolic process|cellular_component-&-1&-GO:0043190-&&-ATP-binding cassette (ABC) transporter complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0010008-&&-endosome membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0016020-&&-membrane-%%-GO:0005768-&&-endosome-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0042626-&&-ATPase activity, coupled to transmembrane movement of substances-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0000166-&&-nucleotide binding	G:9606:ABCA2			KEGG-&-1&-hsa02010-&&-ABC transporters-%%-hsa04142-&&-Lysosome	ABCA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABCA2	0.34751424	0.02777778	9	4	FALSE	ABCA2	ABCA2	139	0	9	0	0.68707001	FALSE	0	ABCA2	7408	0.13406617
791856	taxon:9606	2.95415157	7.80E-07	182968	1902	acetyl-CoA carboxylase beta	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0031325-&&-positive regulation of cellular metabolic process-%%-GO:0006084-&&-acetyl-CoA metabolic process-%%-GO:0010884-&&-positive regulation of lipid storage-%%-GO:0006768-&&-biotin metabolic process-%%-GO:0006853-&&-carnitine shuttle-%%-GO:0042493-&&-response to drug-%%-GO:0060421-&&-positive regulation of heart growth-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:2001295-&&-malonyl-CoA biosynthetic process-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0031999-&&-negative regulation of fatty acid beta-oxidation-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0097009-&&-energy homeostasis|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004075-&&-biotin carboxylase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0003989-&&-acetyl-CoA carboxylase activity-%%-GO:0009374-&&-biotin binding	G:9606:ACACB			KEGG-&-1&-hsa00620-&&-Pyruvate metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00640-&&-Propanoate metabolism-%%-hsa04931-&&-Insulin resistance-%%-hsa04920-&&-Adipocytokine signaling pathway	ACACB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACACB	0.33850667	0.47222222	9	5	FALSE	ACACB	ACACB	161.4444444	0	9	0	0.67430807	FALSE	0	ACACB	2176	0.21061793
791902	taxon:9606	3.37056877	1.43E-05	182901	1902	aggrecan	gene	biological_process-&-1&-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0007417-&&-central nervous system development-%%-GO:0042340-&&-keratan sulfate catabolic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0001501-&&-skeletal system development-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0005201-&&-extracellular matrix structural constituent-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005540-&&-hyaluronic acid binding	G:9606:ACAN	ACAN	TRUE		ACAN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAN	0.29668583	0.08333333	9	5	FALSE	ACAN	ACAN	21.11111111	0	9	0	0.6049052	FALSE	0	ACAN	10442	0.14475743
791905	taxon:9606	2.98408697	1.37E-05	182893	1902	angiotensin II receptor type 2	gene	biological_process-&-1&-GO:0035566-&&-regulation of metanephros size-%%-GO:0042990-&&-regulation of transcription factor import into nucleus-%%-GO:0010700-&&-negative regulation of norepinephrine secretion-%%-GO:0002033-&&-angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0072300-&&-positive regulation of metanephric glomerulus development-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0038166-&&-angiotensin-activated signaling pathway-%%-GO:0007420-&&-brain development-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:1900116-&&-extracellular negative regulation of signal transduction-%%-GO:0032304-&&-negative regulation of icosanoid secretion-%%-GO:0006954-&&-inflammatory response-%%-GO:0051000-&&-positive regulation of nitric-oxide synthase activity-%%-GO:0006883-&&-cellular sodium ion homeostasis-%%-GO:0007199-&&-G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger-%%-GO:0061049-&&-cell growth involved in cardiac muscle cell development-%%-GO:0002035-&&-brain renin-angiotensin system-%%-GO:0002018-&&-renin-angiotensin regulation of aldosterone production-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0035932-&&-aldosterone secretion-%%-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010459-&&-negative regulation of heart rate-%%-GO:0001991-&&-regulation of systemic arterial blood pressure by circulatory renin-angiotensin-%%-GO:0051387-&&-negative regulation of neurotrophin TRK receptor signaling pathway-%%-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0035640-&&-exploration behavior-%%-GO:0021695-&&-cerebellar cortex development-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:0042311-&&-vasodilation-%%-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0032516-&&-positive regulation of phosphoprotein phosphatase activity-%%-GO:0071549-&&-cellular response to dexamethasone stimulus|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0048019-&&-receptor antagonist activity-%%-GO:0005515-&&-protein binding-%%-GO:0017046-&&-peptide hormone binding-%%-GO:0004945-&&-angiotensin type II receptor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:AGTR2	AGTR2	TRUE	KEGG-&-1&-hsa04614-&&-Renin-angiotensin system-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	AGTR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGTR2	0.33511088	0.05555556	9	4	FALSE	AGTR2	AGTR2	62.88888889	0	9	0	0.66931884	FALSE	0	AGTR2	15136	0.12773224
791941	taxon:9606	2.96959193	2.89E-05	182835	1902	adenosylmethionine decarboxylase 1	gene	biological_process-&-1&-GO:0006557-&&-S-adenosylmethioninamine biosynthetic process-%%-GO:0006597-&&-spermine biosynthetic process-%%-GO:0006595-&&-polyamine metabolic process-%%-GO:0046500-&&-S-adenosylmethionine metabolic process-%%-GO:0008295-&&-spermidine biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004014-&&-adenosylmethionine decarboxylase activity-%%-GO:0019810-&&-putrescine binding	G:9606:AMD1			KEGG-&-1&-hsa00270-&&-Cysteine and methionine metabolism-%%-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways	AMD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMD1	0.3367466	0	9	5	FALSE	AMD1	AMD1	100.5714286	0	8	0	0.67173468	FALSE	1	AMD1	15136	0.14973147
791971	taxon:9606	2.7197101	2.65E-06	166403	1902	G elongation factor mitochondrial 1	gene	biological_process-&-1&-GO:0070125-&&-mitochondrial translational elongation|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005525-&&-GTP binding-%%-GO:0003746-&&-translation elongation factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity	G:9606:GFM1				GFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFM1	0.36768625	0.19444444	9	4	FALSE	GFM1	GFM1	271.3333333	0	9	0	0.71338165	FALSE	0	GFM1	8984	0.1410412
791988	taxon:9606	3.01449504	5.75E-06	182770	1902	apolipoprotein A2	gene	biological_process-&-1&-GO:0031100-&&-animal organ regeneration-%%-GO:0010873-&&-positive regulation of cholesterol esterification-%%-GO:0043627-&&-response to estrogen-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0046340-&&-diacylglycerol catabolic process-%%-GO:0050996-&&-positive regulation of lipid catabolic process-%%-GO:0002526-&&-acute inflammatory response-%%-GO:0034380-&&-high-density lipoprotein particle assembly-%%-GO:0002740-&&-negative regulation of cytokine secretion involved in immune response-%%-GO:0060192-&&-negative regulation of lipase activity-%%-GO:0006641-&&-triglyceride metabolic process-%%-GO:0016032-&&-viral process-%%-GO:0042493-&&-response to drug-%%-GO:0031647-&&-regulation of protein stability-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0034370-&&-triglyceride-rich lipoprotein particle remodeling-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0030300-&&-regulation of intestinal cholesterol absorption-%%-GO:0060695-&&-negative regulation of cholesterol transporter activity-%%-GO:0033344-&&-cholesterol efflux-%%-GO:0010903-&&-negative regulation of very-low-density lipoprotein particle remodeling-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0060621-&&-negative regulation of cholesterol import-%%-GO:0034375-&&-high-density lipoprotein particle remodeling-%%-GO:0034384-&&-high-density lipoprotein particle clearance-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0050995-&&-negative regulation of lipid catabolic process-%%-GO:0045416-&&-positive regulation of interleukin-8 biosynthetic process-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:0018158-&&-protein oxidation-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0018206-&&-peptidyl-methionine modification-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0033700-&&-phospholipid efflux-%%-GO:0032375-&&-negative regulation of cholesterol transport-%%-GO:0009749-&&-response to glucose|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0042627-&&-chylomicron-%%-GO:0034361-&&-very-low-density lipoprotein particle-%%-GO:0034364-&&-high-density lipoprotein particle-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0034366-&&-spherical high-density lipoprotein particle|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005319-&&-lipid transporter activity-%%-GO:0060228-&&-phosphatidylcholine-sterol O-acyltransferase activator activity-%%-GO:0055102-&&-lipase inhibitor activity-%%-GO:0017127-&&-cholesterol transporter activity-%%-GO:0070653-&&-high-density lipoprotein particle receptor binding-%%-GO:0008035-&&-high-density lipoprotein particle binding-%%-GO:0005543-&&-phospholipid binding-%%-GO:0031210-&&-phosphatidylcholine binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008289-&&-lipid binding-%%-GO:0034190-&&-apolipoprotein receptor binding	G:9606:APOA2			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa03320-&&-PPAR signaling pathway	APOA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APOA2	0.33173052	0.33333333	9	5	FALSE	APOA2	APOA2	79.71428571	0	8	0	0.66425083	FALSE	1	APOA2	4516	0.15691789
792024	taxon:9606	2.70285174	9.63E-06	182717	1902	biliverdin reductase A	gene	biological_process-&-1&-GO:0042167-&&-heme catabolic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004074-&&-biliverdin reductase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:BLVRA			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism	BLVRA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLVRA	0.3699796	0.16666667	9	4	FALSE	BLVRA	BLVRA	276	0	9	0	0.71619138	FALSE	0	BLVRA	14572	0.1383311
792094	taxon:9606	2.87253821	1.71E-06	182618	1902	calponin 1	gene	biological_process-&-1&-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0031032-&&-actomyosin structure organization|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:CNN1				CNN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNN1	0.34812418	0.19444444	9	5	FALSE	CNN1	CNN1	136.4444444	0	9	0	0.6879103	FALSE	0	CNN1	2892	0.14124684
792107	taxon:9606	2.74003466	2.18E-05	182597	1902	collagen type IV alpha 6 chain	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005587-&&-collagen type IV trimer|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL4A6			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05222-&&-Small cell lung cancer	COL4A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A6	0.36495889	0.16666667	9	4	FALSE	COL4A6	COL4A6	245.1111111	0	9	0	0.70999422	FALSE	0	COL4A6	27804	0.1390624
792112	taxon:9606	2.91523554	8.39E-06	182589	1902	collagen type VIII alpha 2 chain	gene	biological_process-&-1&-GO:0048593-&&-camera-type eye morphogenesis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0016337-&&-single organismal cell-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005581-&&-collagen trimer-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005604-&&-basement membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0030674-&&-protein binding, bridging-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL8A2				COL8A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL8A2	0.34302546	0.05555556	9	5	FALSE	COL8A2	COL8A2	108.5555556	0	9	0	0.68079408	FALSE	0	COL8A2	8666	0.12204625
792176	taxon:9606	2.82716244	9.42E-06	166091	1902	splA/ryanodine receptor domain and SOCS box containing 3	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPSB3				SPSB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPSB3	0.35371155	0.11111111	9	5	FALSE	SPSB3	SPSB3	171.1111111	0	9	0	0.69547293	FALSE	0	SPSB3	10672	0.13427747
792201	taxon:9606	2.99322515	1.99E-05	166055	1902	transmembrane protein 259	gene	biological_process-&-1&-GO:1901215-&&-negative regulation of neuron death-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:1904294-&&-positive regulation of ERAD pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane	G:9606:TMEM259				TMEM259	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM259	0.3340878	0.11111111	9	4	FALSE	TMEM259	TMEM259	75.66666667	0	9	0	0.66779581	FALSE	0	TMEM259	14240	0.12394573
792371	taxon:9606	2.9335119	2.19E-05	182136	1902	ceruloplasmin	gene	biological_process-&-1&-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006825-&&-copper ion transport|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0004322-&&-ferroxidase activity-%%-GO:0005507-&&-copper ion binding	G:9606:CP	CP	TRUE	KEGG-&-1&-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa04216-&&-Ferroptosis	CP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CP	0.34088834	0.05555556	9	5	FALSE	CP	CP	101.4444444	0	9	0	0.67774802	FALSE	0	CP	21024	0.12868481
792388	taxon:9606	2.82558689	2.33E-06	165721	1902	twist family bHLH transcription factor 2	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045668-&&-negative regulation of osteoblast differentiation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding	G:9606:TWIST2			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	TWIST2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TWIST2	0.35390878	0.22222222	9	4	FALSE	TWIST2	TWIST2	176.6666667	0	9	0	0.69573552	FALSE	0	TWIST2	4210	0.13296492
792490	taxon:9606	2.88703324	5.76E-06	165549	1902	kelch like family member 29	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL29				KLHL29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL29	0.34637634	0.05555556	9	4	FALSE	KLHL29	KLHL29	130.5555556	0	9	0	0.68549446	FALSE	0	KLHL29	6806	0.1371308
792618	taxon:9606	2.97857255	1.42E-06	181705	1902	thymidine phosphorylase	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0043097-&&-pyrimidine nucleoside salvage-%%-GO:0001525-&&-angiogenesis-%%-GO:0006206-&&-pyrimidine nucleobase metabolic process-%%-GO:0046135-&&-pyrimidine nucleoside catabolic process-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004645-&&-phosphorylase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0009032-&&-thymidine phosphorylase activity-%%-GO:0016154-&&-pyrimidine-nucleoside phosphorylase activity-%%-GO:0016763-&&-transferase activity, transferring pentosyl groups	G:9606:TYMP			KEGG-&-1&-hsa05219-&&-Bladder cancer-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	TYMP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYMP	0.33573129	0.28571429	9	4	FALSE	TYMP	TYMP	85.28571429	0	8	0	0.67023791	FALSE	1	TYMP	2150	0.17091326
792648	taxon:9606	2.94485584	3.25E-05	181641	1902	CD53 molecule	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:1901741-&&-positive regulation of myoblast fusion|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0001772-&&-immunological synapse|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CD53				CD53	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD53	0.3395752	0.22222222	9	5	FALSE	CD53	CD53	96.88888889	0	9	0	0.67585736	FALSE	0	CD53	34550	0.13065704
792657	taxon:9606	3.01055617	3.64E-05	181627	1902	cytochrome P450 family 2 subfamily C member 9	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0032787-&&-monocarboxylic acid metabolic process-%%-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043603-&&-cellular amide metabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0042737-&&-drug catabolic process-%%-GO:0070989-&&-oxidative demethylation-%%-GO:0097267-&&-omega-hydroxylase P450 pathway-%%-GO:0019627-&&-urea metabolic process-%%-GO:0042738-&&-exogenous drug catabolic process|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0018675-&&-(S)-limonene 6-monooxygenase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0008392-&&-arachidonic acid epoxygenase activity-%%-GO:0001567-&&-cholesterol 25-hydroxylase activity-%%-GO:0018676-&&-(S)-limonene 7-monooxygenase activity-%%-GO:0008395-&&-steroid hydroxylase activity-%%-GO:0034875-&&-caffeine oxidase activity-%%-GO:0020037-&&-heme binding-%%-GO:0052741-&&-(R)-limonene 6-monooxygenase activity-%%-GO:0008144-&&-drug binding	G:9606:CYP2C9			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa01100-&&-Metabolic pathways-%%-hsa04726-&&-Serotonergic synapse-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00830-&&-Retinol metabolism	CYP2C9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP2C9	0.33216454	0.22222222	9	5	FALSE	CYP2C9	CYP2C9	61.55555556	0	9	0	0.66490731	FALSE	0	CYP2C9	34482	0.13479853
792757	taxon:9606	2.87553175	8.38E-06	181431	1902	glypican 4	gene	biological_process-&-1&-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005634-&&-nucleus-%%-GO:0031225-&&-anchored component of membrane|molecular_function-&-1&-GO:1904929-&&-coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway-%%-GO:0043395-&&-heparan sulfate proteoglycan binding	G:9606:GPC4	GPC4	TRUE	KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	GPC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPC4	0.34776177	0.11111111	9	5	FALSE	GPC4	GPC4	135.4444444	0	9	0	0.68741138	FALSE	0	GPC4	7000	0.13070629
792763	taxon:9606	2.86639357	1.01E-05	181413	1902	fibroblast growth factor 13	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006814-&&-sodium ion transport-%%-GO:0007612-&&-learning-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0021795-&&-cerebral cortex cell migration-%%-GO:0045200-&&-establishment of neuroblast polarity-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:1990834-&&-response to odorant-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0098909-&&-regulation of cardiac muscle cell action potential involved in regulation of contraction-%%-GO:0007613-&&-memory-%%-GO:0046785-&&-microtubule polymerization-%%-GO:0048671-&&-negative regulation of collateral sprouting-%%-GO:0001764-&&-neuron migration-%%-GO:0021766-&&-hippocampus development-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005874-&&-microtubule-%%-GO:0005737-&&-cytoplasm-%%-GO:0030424-&&-axon-%%-GO:0005886-&&-plasma membrane-%%-GO:0030175-&&-filopodium-%%-GO:0005634-&&-nucleus-%%-GO:0014704-&&-intercalated disc-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0030426-&&-growth cone-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0048487-&&-beta-tubulin binding-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0005515-&&-protein binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0008017-&&-microtubule binding-%%-GO:0044325-&&-ion channel binding	G:9606:FGF13	FGF13	TRUE		FGF13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGF13	0.34887044	0.19047619	9	5	FALSE	FGF13	FGF13	177.4285714	0	8	0	0.6889344	FALSE	1	FGF13	6004	0.15417133
792783	taxon:9606	2.77595715	2.38E-06	164984	1902	DnaJ heat shock protein family (Hsp40) member C21	gene	biological_process-&-1&-GO:0006457-&&-protein folding|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJC21				DNAJC21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC21	0.36023611	0.13888889	9	5	FALSE	DNAJC21	DNAJC21	264.3333333	0	9	0	0.70400714	FALSE	0	DNAJC21	5570	0.16333402
792807	taxon:9606	2.6932409	4.35E-06	181337	1902	ELAV like RNA binding protein 3	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0030154-&&-cell differentiation|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:ELAVL3				ELAVL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ELAVL3	0.37129987	0.47222222	9	4	FALSE	ELAVL3	ELAVL3	296.7777778	0	9	0	0.71779318	FALSE	0	ELAVL3	10792	0.14357899
792876	taxon:9606	2.62895856	6.72E-06	181237	1902	ETS variant 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0097011-&&-cellular response to granulocyte macrophage colony-stimulating factor stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0090571-&&-RNA polymerase II transcription repressor complex-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003674-&&-molecular_function-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:ETV3				ETV3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ETV3	0.38037876	0.16666667	9	4	FALSE	ETV3	ETV3	360	0	9	0	0.72850691	FALSE	0	ETV3	12146	0.1469827
792929	taxon:9606	3.05435639	2.56E-06	181121	1902	fatty acid binding protein 7	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0006810-&&-transport-%%-GO:0007399-&&-nervous system development-%%-GO:0060134-&&-prepulse inhibition-%%-GO:0021846-&&-cell proliferation in forebrain-%%-GO:0022008-&&-neurogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0042995-&&-cell projection-%%-GO:0071944-&&-cell periphery-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0008289-&&-lipid binding	G:9606:FABP7			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	FABP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FABP7	0.32740122	0.38888889	9	5	FALSE	FABP7	FABP7	72	0	9	0	0.65760727	FALSE	0	FABP7	2912	0.17619826
792937	taxon:9606	2.82464156	1.36E-05	181113	1902	fumarylacetoacetate hydrolase	gene	biological_process-&-1&-GO:0006527-&&-arginine catabolic process-%%-GO:0006572-&&-tyrosine catabolic process-%%-GO:0006559-&&-L-phenylalanine catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004334-&&-fumarylacetoacetase activity	G:9606:FAH			KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa01100-&&-Metabolic pathways	FAH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAH	0.35402722	0.19444444	9	4	FALSE	FAH	FAH	159.7777778	0	9	0	0.69589307	FALSE	0	FAH	15442	0.12446873
793043	taxon:9606	2.89034189	5.93E-05	180844	1902	C-X-C motif chemokine ligand 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0006954-&&-inflammatory response-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006935-&&-chemotaxis-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006955-&&-immune response-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0035580-&&-specific granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0045236-&&-CXCR chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0008047-&&-enzyme activator activity	G:9606:CXCL1			KEGG-&-1&-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05120-&&-Epithelial cell signaling in Helicobacter pylori infection-%%-hsa05134-&&-Legionellosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CXCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL1	0.34597983	0.04761905	9	4	FALSE	CXCL1	CXCL1	141.5714286	0	8	0	0.68494302	FALSE	1	CXCL1	63292	0.15081065
793052	taxon:9606	3.11533008	5.17E-05	180824	1902	glutathione S-transferase mu 1	gene	biological_process-&-1&-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0018916-&&-nitrobenzene metabolic process-%%-GO:0070458-&&-cellular detoxification of nitrogen compound-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043295-&&-glutathione binding	G:9606:GSTM1	GSTM1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05204-&&-Chemical carcinogenesis	GSTM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTM1	0.32099327	0.04761905	9	5	FALSE	GSTM1	GSTM1	45.85714286	0	8	0	0.64744499	FALSE	1	GSTM1	57136	0.1514861
793135	taxon:9606	2.91318733	1.46E-06	164284	1902	prostaglandin reductase 2	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006693-&&-prostaglandin metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0047522-&&-15-oxoprostaglandin 13-oxidase activity-%%-GO:0036132-&&-13-prostaglandin reductase activity	G:9606:PTGR2				PTGR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGR2	0.34326663	0.05555556	9	5	FALSE	PTGR2	PTGR2	121.8888889	0	9	0	0.68113544	FALSE	0	PTGR2	2754	0.1500275
793170	taxon:9606	2.98219631	1.91E-06	180602	1902	G protein subunit gamma 4	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:GNG4			KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04014-&&-Ras signaling pathway-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNG4	0.33532333	0.36111111	9	4	FALSE	GNG4	GNG4	77	0	9	0	0.66963395	FALSE	0	GNG4	2626	0.15233686
793172	taxon:9606	2.92957303	4.08E-06	180597	1902	G protein subunit gamma 11	gene	biological_process-&-1&-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0003924-&&-GTPase activity	G:9606:GNG11			KEGG-&-1&-hsa04014-&&-Ras signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa04713-&&-Circadian entrainment-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	GNG11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNG11	0.34134667	0.05555556	9	5	FALSE	GNG11	GNG11	104.3333333	0	9	0	0.6784045	FALSE	0	GNG11	6074	0.12719836
793179	taxon:9606	2.84449346	3.81E-06	180576	1902	homeobox C11	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007492-&&-endoderm development-%%-GO:0001759-&&-organ induction-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0001656-&&-metanephros development-%%-GO:0042733-&&-embryonic digit morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0060272-&&-embryonic skeletal joint morphogenesis|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:HOXC11				HOXC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXC11	0.35155644	0.16666667	9	5	FALSE	HOXC11	HOXC11	172.8888889	0	9	0	0.69258442	FALSE	0	HOXC11	6096	0.14509804
793183	taxon:9606	2.88293682	1.92E-06	164184	1902	family with sequence similarity 117 member B	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FAM117B				FAM117B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM117B	0.34686851	0.11111111	9	4	FALSE	FAM117B	FAM117B	127.6666667	0	9	0	0.6861772	FALSE	0	FAM117B	3968	0.12953544
793243	taxon:9606	2.91413266	4.81E-06	180463	1902	islet cell autoantigen 1	gene	biological_process-&-1&-GO:0006836-&&-neurotransmitter transport-%%-GO:0050796-&&-regulation of insulin secretion|cellular_component-&-1&-GO:0030667-&&-secretory granule membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005515-&&-protein binding	G:9606:ICA1			KEGG-&-1&-hsa04940-&&-Type I diabetes mellitus	ICA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICA1	0.34315528	0.05555556	9	4	FALSE	ICA1	ICA1	111.3333333	0	9	0	0.68097789	FALSE	0	ICA1	6074	0.12363591
793261	taxon:9606	2.95887821	4.75E-06	180414	1902	guanylate cyclase 1 soluble subunit alpha 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007165-&&-signal transduction-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process-%%-GO:0006182-&&-cGMP biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008074-&&-guanylate cyclase complex, soluble|molecular_function-&-1&-GO:0004016-&&-adenylate cyclase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0004383-&&-guanylate cyclase activity	G:9606:GUCY1A2			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04713-&&-Circadian entrainment-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	GUCY1A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUCY1A2	0.33796592	0.19444444	9	4	FALSE	GUCY1A2	GUCY1A2	91.33333333	0	9	0	0.6735203	FALSE	0	GUCY1A2	5606	0.15203704
793266	taxon:9606	2.74239798	1.19E-06	164023	1902	zinc finger protein 420	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF420				ZNF420	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF420	0.36464438	0.36111111	9	4	FALSE	ZNF420	ZNF420	276.4444444	0	9	0	0.70960034	FALSE	0	ZNF420	3354	0.158149
787020	taxon:9606	2.80242634	3.24E-06	180217	1902	integrin subunit beta 6	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0033627-&&-cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0006954-&&-inflammatory response-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0007229-&&-integrin-mediated signaling pathway|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0043235-&&-receptor complex-%%-GO:0008305-&&-integrin complex|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding	G:9606:ITGB6			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB6	0.35683364	0.28571429	8	5	FALSE	ITGB6	ITGB6	208.875	0	8	0	0.69959561	FALSE	0	ITGB6	7146	0.15403761
787033	taxon:9606	2.8708051	1.14E-05	180194	1902	hippocalcin	gene	biological_process-&-1&-GO:0019722-&&-calcium-mediated signaling-%%-GO:0045762-&&-positive regulation of adenylate cyclase activity-%%-GO:0048839-&&-inner ear development-%%-GO:1901986-&&-response to ketamine-%%-GO:0031584-&&-activation of phospholipase D activity-%%-GO:0090314-&&-positive regulation of protein targeting to membrane-%%-GO:0007420-&&-brain development-%%-GO:0071257-&&-cellular response to electrical stimulus-%%-GO:1902065-&&-response to L-glutamate-%%-GO:1904009-&&-cellular response to monosodium glutamate-%%-GO:1904010-&&-response to Aroclor 1254-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0031283-&&-negative regulation of guanylate cyclase activity|cellular_component-&-1&-GO:0032809-&&-neuronal cell body membrane-%%-GO:0044327-&&-dendritic spine head-%%-GO:0030424-&&-axon-%%-GO:0032590-&&-dendrite membrane-%%-GO:0043204-&&-perikaryon-%%-GO:0032839-&&-dendrite cytoplasm|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0019900-&&-kinase binding	G:9606:HPCA				HPCA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPCA	0.34833434	0.03571429	8	4	FALSE	HPCA	HPCA	159.5	0	8	0	0.68819915	FALSE	0	HPCA	10298	0.1434056
787050	taxon:9606	2.93949898	1.67E-06	163777	1902	zinc finger protein, FOG family member 1	gene	biological_process-&-1&-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0030219-&&-megakaryocyte differentiation-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0055008-&&-cardiac muscle tissue morphogenesis-%%-GO:0030851-&&-granulocyte differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010724-&&-regulation of definitive erythrocyte differentiation-%%-GO:0002295-&&-T-helper cell lineage commitment-%%-GO:0007507-&&-heart development-%%-GO:0007596-&&-blood coagulation-%%-GO:0060319-&&-primitive erythrocyte differentiation-%%-GO:0035855-&&-megakaryocyte development-%%-GO:0045078-&&-positive regulation of interferon-gamma biosynthetic process-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0032642-&&-regulation of chemokine production-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0030220-&&-platelet formation-%%-GO:0045403-&&-negative regulation of interleukin-4 biosynthetic process-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0003195-&&-tricuspid valve formation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060318-&&-definitive erythrocyte differentiation-%%-GO:0035162-&&-embryonic hemopoiesis-%%-GO:0071733-&&-transcriptional activation by promoter-enhancer looping-%%-GO:0003192-&&-mitral valve formation-%%-GO:0060377-&&-negative regulation of mast cell differentiation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding-%%-GO:0001085-&&-RNA polymerase II transcription factor binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding	G:9606:ZFPM1				ZFPM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFPM1	0.34019403	0.07142857	8	5	FALSE	ZFPM1	ZFPM1	109.625	0	8	0	0.67675017	FALSE	0	ZFPM1	2416	0.15219665
787065	taxon:9606	2.97037971	6.03E-06	180129	1902	interferon gamma receptor 2	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004906-&&-interferon-gamma receptor activity-%%-GO:0004920-&&-interleukin-10 receptor activity	G:9606:IFNGR2			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05132-&&-Salmonella infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04217-&&-Necroptosis-%%-hsa04066-&&-HIF-1 signaling pathway	IFNGR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNGR2	0.3366573	0.10714286	8	5	FALSE	IFNGR2	IFNGR2	77.75	0	8	0	0.67160338	FALSE	0	IFNGR2	6898	0.13893885
787101	taxon:9606	3.01449504	1.01E-04	180058	1902	interleukin 1 receptor antagonist	gene	biological_process-&-1&-GO:0030073-&&-insulin secretion-%%-GO:0006955-&&-immune response-%%-GO:0006954-&&-inflammatory response-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0006629-&&-lipid metabolic process-%%-GO:2000660-&&-negative regulation of interleukin-1-mediated signaling pathway-%%-GO:0051384-&&-response to glucocorticoid|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0045352-&&-interleukin-1 Type I receptor antagonist activity-%%-GO:0045353-&&-interleukin-1 Type II receptor antagonist activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005151-&&-interleukin-1, Type II receptor binding-%%-GO:0005152-&&-interleukin-1 receptor antagonist activity-%%-GO:0005515-&&-protein binding-%%-GO:0005150-&&-interleukin-1, Type I receptor binding	G:9606:IL1RN	IL1RN	TRUE	KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	IL1RN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1RN	0.33173052	0.06666667	8	5	FALSE	IL1RN	IL1RN	90.33333333	0	7	0	0.66425083	FALSE	1	IL1RN	99962	0.17755776
787138	taxon:9606	3.73152671	5.53E-06	180000	1902	C-X-C motif chemokine ligand 10	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0009409-&&-response to cold-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0034605-&&-cellular response to heat-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0010819-&&-regulation of T cell chemotaxis-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0006954-&&-inflammatory response-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006955-&&-immune response-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0006935-&&-chemotaxis-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:1901509-&&-regulation of endothelial tube morphogenesis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:2000406-&&-positive regulation of T cell migration-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0008015-&&-blood circulation-%%-GO:0042118-&&-endothelial cell activation-%%-GO:0051607-&&-defense response to virus-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0007517-&&-muscle organ development-%%-GO:0030816-&&-positive regulation of cAMP metabolic process-%%-GO:0033280-&&-response to vitamin D-%%-GO:1901740-&&-negative regulation of myoblast fusion-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0008603-&&-cAMP-dependent protein kinase regulator activity-%%-GO:0008201-&&-heparin binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0048248-&&-CXCR3 chemokine receptor binding	G:9606:CXCL10	CXCL10	TRUE	KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL10	0.26798683	0	8	5	FALSE	CXCL10	CXCL10	17	0	7	0	0.54474555	FALSE	1	CXCL10	4030	0.21333333
787257	taxon:9606	2.86544824	6.62E-06	163404	1902	consortin, connexin sorting protein	gene	biological_process-&-1&-GO:0042998-&&-positive regulation of Golgi to plasma membrane protein transport-%%-GO:0010923-&&-negative regulation of phosphatase activity|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030133-&&-transport vesicle-%%-GO:0043234-&&-protein complex-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0071253-&&-connexin binding-%%-GO:0019902-&&-phosphatase binding-%%-GO:0005515-&&-protein binding	G:9606:CNST				CNST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNST	0.34898554	0.14285714	8	4	FALSE	CNST	CNST	165.75	0	8	0	0.68909196	FALSE	0	CNST	7212	0.15639754
787265	taxon:9606	3.07861982	3.16E-06	163392	1902	coiled-coil domain containing 116	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC116				CCDC116	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC116	0.32482088	0	8	5	FALSE	CCDC116	CCDC116	69.625	0	8	0	0.65356336	FALSE	0	CCDC116	4124	0.14663462
787282	taxon:9606	3.12635891	3.73E-06	179745	1902	potassium voltage-gated channel subfamily J member 6	gene	biological_process-&-1&-GO:0010107-&&-potassium ion import-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0015467-&&-G-protein activated inward rectifier potassium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0005242-&&-inward rectifier potassium channel activity	G:9606:KCNJ6			KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa05032-&&-Morphine addiction-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04727-&&-GABAergic synapse-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	KCNJ6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNJ6	0.31986091	0.33333333	8	5	FALSE	KCNJ6	KCNJ6	64	0	7	0	0.64560685	FALSE	1	KCNJ6	4364	0.17984934
787299	taxon:9606	2.96328974	1.94E-06	163324	1902	zinc finger protein 467	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF467				ZNF467	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF467	0.33746278	0.28571429	8	5	FALSE	ZNF467	ZNF467	163.25	0	8	0	0.67278504	FALSE	0	ZNF467	3760	0.24274554
787357	taxon:9606	2.87962817	1.86E-06	163215	1902	RNA polymerase III subunit H	gene	biological_process-&-1&-GO:0006139-&&-nucleobase-containing compound metabolic process-%%-GO:0032481-&&-positive regulation of type I interferon production-%%-GO:0045087-&&-innate immune response-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0006384-&&-transcription initiation from RNA polymerase III promoter-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0005666-&&-DNA-directed RNA polymerase III complex-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0001056-&&-RNA polymerase III activity-%%-GO:0003899-&&-DNA-directed 5'-3' RNA polymerase activity	G:9606:POLR3H			KEGG-&-1&-hsa03020-&&-RNA polymerase-%%-hsa04623-&&-Cytosolic DNA-sensing pathway	POLR3H	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POLR3H	0.34726706	0.17857143	8	4	FALSE	POLR3H	POLR3H	161.125	0	8	0	0.68672864	FALSE	0	POLR3H	3248	0.15483638
787392	taxon:9606	2.79045218	1.73E-06	179510	1902	myosin IXA	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007601-&&-visual perception-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016461-&&-unconventional myosin complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003774-&&-motor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:MYO9A				MYO9A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO9A	0.35836486	0.10714286	8	4	FALSE	MYO9A	MYO9A	236.5	0	8	0	0.7015913	FALSE	0	MYO9A	4896	0.15534539
787399	taxon:9606	2.81881204	3.56E-06	163114	1902	THAP domain containing 8	gene	molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:THAP8				THAP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THAP8	0.35475938	0.07142857	8	4	FALSE	THAP8	THAP8	198.875	0	8	0	0.69686466	FALSE	0	THAP8	6414	0.1452381
787421	taxon:9606	2.9818812	7.84E-06	179460	1902	lipocalin 2	gene	biological_process-&-1&-GO:0009615-&&-response to virus-%%-GO:0010046-&&-response to mycotoxin-%%-GO:0006811-&&-ion transport-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0009635-&&-response to herbicide-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0031346-&&-positive regulation of cell projection organization-%%-GO:0045087-&&-innate immune response-%%-GO:0042493-&&-response to drug-%%-GO:0015891-&&-siderophore transport-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0031669-&&-cellular response to nutrient levels|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0035580-&&-specific granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0005215-&&-transporter activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0036094-&&-small molecule binding-%%-GO:0002020-&&-protease binding	G:9606:LCN2	LCN2	TRUE	KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway	LCN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCN2	0.33535877	0	8	4	FALSE	LCN2	LCN2	100.8333333	0	7	0	0.66968647	FALSE	1	LCN2	8096	0.1760729
787479	taxon:9606	2.76744919	4.58E-06	179358	1902	mitochondrial intermediate peptidase	gene	biological_process-&-1&-GO:0006627-&&-protein processing involved in protein targeting to mitochondrion-%%-GO:0006518-&&-peptide metabolic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0046872-&&-metal ion binding	G:9606:MIPEP				MIPEP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MIPEP	0.36134358	0.07142857	8	4	FALSE	MIPEP	MIPEP	265.625	0	8	0	0.70542514	FALSE	0	MIPEP	8586	0.1609745
787631	taxon:9606	3.05593194	1.84E-05	179062	1902	neuropeptide Y	gene	biological_process-&-1&-GO:0032098-&&-regulation of appetite-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0008015-&&-blood circulation-%%-GO:0031175-&&-neuron projection development-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0007586-&&-digestion-%%-GO:0007610-&&-behavior-%%-GO:0006816-&&-calcium ion transport-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0007631-&&-feeding behavior-%%-GO:0032100-&&-positive regulation of appetite-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0021987-&&-cerebral cortex development-%%-GO:0008283-&&-cell proliferation-%%-GO:0008343-&&-adult feeding behavior|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005623-&&-cell-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005184-&&-neuropeptide hormone activity	G:9606:NPY	NPY	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa05034-&&-Alcoholism-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	NPY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPY	0.32723242	0.14285714	8	5	FALSE	NPY	NPY	60.375	0	8	0	0.65734468	FALSE	0	NPY	15220	0.14239387
787640	taxon:9606	2.84874744	8.10E-07	162655	1902	proline rich 14 like	gene		G:9606:PRR14L				PRR14L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRR14L	0.35103147	0.10714286	8	4	FALSE	PRR14L	PRR14L	192.5	0	8	0	0.69187543	FALSE	0	PRR14L	2434	0.16845917
787849	taxon:9606	2.847487	1.48E-06	178721	1902	protein kinase, Y-linked, pseudogene	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:PRKY				PRKY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKY	0.35118685	0.21428571	8	4	FALSE	PRKY	PRKY	210.75	0	8	0	0.6920855	FALSE	0	PRKY	4674	0.18331158
787916	taxon:9606	2.95919332	3.45E-06	178613	1902	prostaglandin-endoperoxide synthase 1	gene	biological_process-&-1&-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004601-&&-peroxidase activity-%%-GO:0004666-&&-prostaglandin-endoperoxide synthase activity-%%-GO:0020037-&&-heme binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity	G:9606:PTGS1	PTGS1	TRUE	KEGG-&-1&-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04726-&&-Serotonergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa04611-&&-Platelet activation-%%-hsa00590-&&-Arachidonic acid metabolism	PTGS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGS1	0.33792993	0.33333333	8	5	FALSE	PTGS1	PTGS1	119.3333333	0	7	0	0.67346778	FALSE	1	PTGS1	3110	0.17839321
787980	taxon:9606	2.91287222	6.51E-06	178466	1902	phosphate cytidylyltransferase 1, choline, alpha	gene	biological_process-&-1&-GO:0006657-&&-CDP-choline pathway-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0042587-&&-glycogen granule-%%-GO:0005635-&&-nuclear envelope|molecular_function-&-1&-GO:0004105-&&-choline-phosphate cytidylyltransferase activity-%%-GO:0005516-&&-calmodulin binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0031210-&&-phosphatidylcholine binding	G:9606:PCYT1A			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00440-&&-Phosphonate and phosphinate metabolism	PCYT1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCYT1A	0.34330376	0.10714286	8	4	FALSE	PCYT1A	PCYT1A	118.25	0	8	0	0.68118796	FALSE	0	PCYT1A	6408	0.14357491
788016	taxon:9606	2.74113755	2.01E-06	178395	1902	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1	gene	biological_process-&-1&-GO:0006003-&&-fructose 2,6-bisphosphate metabolic process-%%-GO:0006094-&&-gluconeogenesis-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0051591-&&-response to cAMP-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0006096-&&-glycolytic process-%%-GO:0033762-&&-response to glucagon-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0016311-&&-dephosphorylation-%%-GO:0032868-&&-response to insulin-%%-GO:0033133-&&-positive regulation of glucokinase activity-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0042594-&&-response to starvation-%%-GO:0051384-&&-response to glucocorticoid|cellular_component-&-1&-GO:0043540-&&-6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004331-&&-fructose-2,6-bisphosphate 2-phosphatase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003873-&&-6-phosphofructo-2-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0019900-&&-kinase binding-%%-GO:0070095-&&-fructose-6-phosphate binding	G:9606:PFKFB1			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04922-&&-Glucagon signaling pathway-%%-hsa04152-&&-AMPK signaling pathway	PFKFB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKFB1	0.36481205	0.06666667	8	5	FALSE	PFKFB1	PFKFB1	352.6666667	0	7	0	0.70981041	FALSE	1	PFKFB1	7544	0.20417633
788152	taxon:9606	3.00141799	3.00E-07	145385	1902	caspase 12 (gene/pseudogene)	gene	biological_process-&-1&-GO:0097194-&&-execution phase of apoptosis-%%-GO:0097264-&&-self proteolysis-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress|cellular_component-&-1&-GO:0097169-&&-AIM2 inflammasome complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0072559-&&-NLRP3 inflammasome complex-%%-GO:0072557-&&-IPAF inflammasome complex|molecular_function-&-1&-GO:0097153-&&-cysteine-type endopeptidase activity involved in apoptotic process	G:9606:CASP12			KEGG-&-1&-hsa05010-&&-Alzheimer disease-%%-hsa04210-&&-Apoptosis-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05014-&&-Amyotrophic lateral sclerosis (ALS)-%%-hsa05020-&&-Prion diseases-%%-hsa05161-&&-Hepatitis B-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	CASP12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CASP12	0.33317585	0.4	8	5	FALSE	CASP12	CASP12	99.33333333	0	7	0	0.66643033	FALSE	1	CASP12	596	0.21054494
788190	taxon:9606	2.89175989	3.66E-06	178107	1902	retinoic acid receptor responder 3	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0036152-&&-phosphatidylethanolamine acyl-chain remodeling-%%-GO:0006644-&&-phospholipid metabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004623-&&-phospholipase A2 activity-%%-GO:0005515-&&-protein binding-%%-GO:0016746-&&-transferase activity, transferring acyl groups	G:9606:RARRES3				RARRES3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RARRES3	0.34581018	0.03571429	8	5	FALSE	RARRES3	RARRES3	130.25	0	8	0	0.68470669	FALSE	0	RARRES3	4718	0.14599775
788203	taxon:9606	2.69733732	1.00E-06	178088	1902	RNA binding motif single stranded interacting protein 2	gene	biological_process-&-1&-GO:0006396-&&-RNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:RBMS2				RBMS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBMS2	0.37073598	0.32142857	8	4	FALSE	RBMS2	RBMS2	369.75	0	8	0	0.71711045	FALSE	0	RBMS2	3390	0.17853694
788256	taxon:9606	2.71892233	6.79E-06	145227	1902	C8orf44-SGK3 readthrough	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0006950-&&-response to stress-%%-GO:0032411-&&-positive regulation of transporter activity|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:C8orf44-SGK3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	C8orf44-SGK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C8orf44-SGK3	0.36779278	0.07142857	8	5	FALSE	C8orf44-SGK3	C8orf44-SGK3	292.375	0	8	0	0.71351295	FALSE	0	C8orf44-SGK3	14524	0.15525266
788371	taxon:9606	2.82716244	1.14E-06	177785	1902	sex determining region Y	gene	biological_process-&-1&-GO:2000020-&&-positive regulation of male gonad development-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007548-&&-sex differentiation-%%-GO:0030238-&&-male sex determination-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0008134-&&-transcription factor binding	G:9606:SRY				SRY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRY	0.35371155	0.46428571	8	5	FALSE	SRY	SRY	238.875	0	8	0	0.69547293	FALSE	0	SRY	1960	0.18838722
788416	taxon:9606	2.99432803	5.45E-06	177709	1902	semenogelin II	gene	biological_process-&-1&-GO:1900005-&&-positive regulation of serine-type endopeptidase activity-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0050817-&&-coagulation-%%-GO:1901318-&&-negative regulation of flagellated sperm motility-%%-GO:0019731-&&-antibacterial humoral response|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:SEMG2				SEMG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEMG2	0.33396475	0.25	8	5	FALSE	SEMG2	SEMG2	61.375	0	8	0	0.667612	FALSE	0	SEMG2	4676	0.13550885
788461	taxon:9606	2.90452182	5.90E-06	177605	1902	solute carrier family 34 member 1	gene	biological_process-&-1&-GO:0044341-&&-sodium-dependent phosphate transport-%%-GO:0030643-&&-cellular phosphate ion homeostasis-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0045838-&&-positive regulation of membrane potential-%%-GO:1901684-&&-arsenate ion transmembrane transport-%%-GO:0006817-&&-phosphate ion transport-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0060416-&&-response to growth hormone-%%-GO:0046689-&&-response to mercury ion-%%-GO:0071374-&&-cellular response to parathyroid hormone stimulus-%%-GO:0035435-&&-phosphate ion transmembrane transport-%%-GO:0035864-&&-response to potassium ion-%%-GO:0046686-&&-response to cadmium ion-%%-GO:0097187-&&-dentinogenesis-%%-GO:2000187-&&-positive regulation of phosphate transmembrane transport-%%-GO:0072350-&&-tricarboxylic acid metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0032026-&&-response to magnesium ion-%%-GO:0033189-&&-response to vitamin A-%%-GO:0071248-&&-cellular response to metal ion-%%-GO:0042431-&&-indole metabolic process-%%-GO:2000120-&&-positive regulation of sodium-dependent phosphate transport-%%-GO:0010288-&&-response to lead ion-%%-GO:0097066-&&-response to thyroid hormone-%%-GO:0055062-&&-phosphate ion homeostasis-%%-GO:0001503-&&-ossification-%%-GO:0072734-&&-cellular response to staurosporine-%%-GO:0001822-&&-kidney development-%%-GO:0032355-&&-response to estradiol-%%-GO:0009100-&&-glycoprotein metabolic process-%%-GO:1901128-&&-gentamycin metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005768-&&-endosome-%%-GO:0009986-&&-cell surface-%%-GO:0031526-&&-brush border membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005903-&&-brush border-%%-GO:0031982-&&-vesicle-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0030165-&&-PDZ domain binding-%%-GO:0005436-&&-sodium:phosphate symporter activity-%%-GO:0015321-&&-sodium-dependent phosphate transmembrane transporter activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0032403-&&-protein complex binding	G:9606:SLC34A1			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	SLC34A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC34A1	0.34429075	0.10714286	8	5	FALSE	SLC34A1	SLC34A1	118.375	0	8	0	0.6825797	FALSE	0	SLC34A1	5888	0.13736903
788479	taxon:9606	2.9700646	3.94E-06	177571	1902	sphingomyelin phosphodiesterase 1	gene	biological_process-&-1&-GO:0046513-&&-ceramide biosynthetic process-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0042220-&&-response to cocaine-%%-GO:0042493-&&-response to drug-%%-GO:0035307-&&-positive regulation of protein dephosphorylation-%%-GO:0023021-&&-termination of signal transduction-%%-GO:0006684-&&-sphingomyelin metabolic process-%%-GO:0006685-&&-sphingomyelin catabolic process-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043407-&&-negative regulation of MAP kinase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005768-&&-endosome-%%-GO:0042599-&&-lamellar body-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004767-&&-sphingomyelin phosphodiesterase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0016798-&&-hydrolase activity, acting on glycosyl bonds-%%-GO:0061750-&&-acid sphingomyelin phosphodiesterase activity	G:9606:SMPD1			KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism-%%-hsa04142-&&-Lysosome-%%-hsa04217-&&-Necroptosis	SMPD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMPD1	0.33669301	0.10714286	8	4	FALSE	SMPD1	SMPD1	90.125	0	8	0	0.6716559	FALSE	0	SMPD1	3936	0.14793388
788501	taxon:9606	3.15613676	1.91E-06	177541	1902	syntrophin beta 1	gene	biological_process-&-1&-GO:0006936-&&-muscle contraction|cellular_component-&-1&-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0045202-&&-synapse-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043234-&&-protein complex-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0003779-&&-actin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:SNTB1				SNTB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNTB1	0.31684305	0.07142857	8	5	FALSE	SNTB1	SNTB1	31.25	0	8	0	0.64064387	FALSE	0	SNTB1	1664	0.14377934
788563	taxon:9606	2.85520718	1.66E-05	177429	1902	tachykinin precursor 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:2000854-&&-positive regulation of corticosterone secretion-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0008306-&&-associative learning-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0009582-&&-detection of abiotic stimulus-%%-GO:0007616-&&-long-term memory-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:0007217-&&-tachykinin receptor signaling pathway-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0045760-&&-positive regulation of action potential-%%-GO:0046878-&&-positive regulation of saliva secretion-%%-GO:0007320-&&-insemination-%%-GO:0010459-&&-negative regulation of heart rate-%%-GO:0032230-&&-positive regulation of synaptic transmission, GABAergic-%%-GO:0043278-&&-response to morphine-%%-GO:0048265-&&-response to pain-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0050671-&&-positive regulation of lymphocyte proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0032224-&&-positive regulation of synaptic transmission, cholinergic-%%-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0009725-&&-response to hormone-%%-GO:0019233-&&-sensory perception of pain|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0031835-&&-substance P receptor binding	G:9606:TAC1			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	TAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAC1	0.35023728	0.14285714	8	5	FALSE	TAC1	TAC1	159.5	0	8	0	0.6907988	FALSE	0	TAC1	22504	0.14256938
788580	taxon:9606	2.98708051	2.00E-06	177406	1902	TAL bHLH transcription factor 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0009791-&&-post-embryonic development-%%-GO:0030901-&&-midbrain development-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0021794-&&-thalamus development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:TAL2				TAL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAL2	0.33477504	0.35714286	8	5	FALSE	TAL2	TAL2	91	0	8	0	0.66881991	FALSE	0	TAL2	2368	0.15171119
788601	taxon:9606	3.09642351	6.85E-06	160982	1902	FRAS1 related extracellular matrix protein 2	gene	biological_process-&-1&-GO:0007154-&&-cell communication-%%-GO:0007507-&&-heart development-%%-GO:0048839-&&-inner ear development-%%-GO:0007155-&&-cell adhesion-%%-GO:0002009-&&-morphogenesis of an epithelium|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:FREM2				FREM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FREM2	0.32295324	0	8	5	FALSE	FREM2	FREM2	44.75	0	8	0	0.65059608	FALSE	0	FREM2	5450	0.13888889
788697	taxon:9606	2.77485426	8.29E-06	177161	1902	troponin T2, cardiac type	gene	biological_process-&-1&-GO:0051592-&&-response to calcium ion-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0055010-&&-ventricular cardiac muscle tissue morphogenesis-%%-GO:0008016-&&-regulation of heart contraction-%%-GO:0030049-&&-muscle filament sliding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0051764-&&-actin crosslink formation-%%-GO:0032972-&&-regulation of muscle filament sliding speed-%%-GO:0032780-&&-negative regulation of ATPase activity|cellular_component-&-1&-GO:0005861-&&-troponin complex-%%-GO:0030017-&&-sarcomere-%%-GO:0005865-&&-striated muscle thin filament-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0030172-&&-troponin C binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0005523-&&-tropomyosin binding-%%-GO:0005515-&&-protein binding-%%-GO:0031013-&&-troponin I binding	G:9606:TNNT2			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	TNNT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNNT2	0.36037929	0.07142857	8	5	FALSE	TNNT2	TNNT2	220.125	0	8	0	0.70419096	FALSE	0	TNNT2	10154	0.13988854
788753	taxon:9606	2.8426028	2.36E-06	177009	1902	zinc finger protein 133	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF133				ZNF133	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF133	0.35179027	0.07142857	8	5	FALSE	ZNF133	ZNF133	178.375	0	8	0	0.69289953	FALSE	0	ZNF133	4740	0.15218322
788795	taxon:9606	2.98298409	2.05E-06	160481	1902	cytosolic thiouridylase subunit 2	gene	biological_process-&-1&-GO:0006400-&&-tRNA modification-%%-GO:0002143-&&-tRNA wobble position uridine thiolation-%%-GO:0034227-&&-tRNA thio-modification-%%-GO:0002098-&&-tRNA wobble uridine modification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016783-&&-sulfurtransferase activity-%%-GO:0000049-&&-tRNA binding	G:9606:CTU2			KEGG-&-1&-hsa04122-&&-Sulfur relay system	CTU2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTU2	0.33523478	0.10714286	8	5	FALSE	CTU2	CTU2	80	0	8	0	0.66950265	FALSE	0	CTU2	2778	0.14537546
788837	taxon:9606	2.70348196	9.60E-07	176776	1902	uridine-cytidine kinase 2	gene	biological_process-&-1&-GO:0044211-&&-CTP salvage-%%-GO:0043097-&&-pyrimidine nucleoside salvage-%%-GO:0006206-&&-pyrimidine nucleobase metabolic process-%%-GO:0044206-&&-UMP salvage-%%-GO:0006238-&&-CMP salvage-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004849-&&-uridine kinase activity-%%-GO:0019206-&&-nucleoside kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:UCK2			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	UCK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UCK2	0.36989335	0.2	8	4	FALSE	UCK2	UCK2	459	0	7	0	0.71608634	FALSE	1	UCK2	4182	0.2311828
788838	taxon:9606	2.98109343	6.48E-06	176778	1902	UDP glycosyltransferase 8	gene	biological_process-&-1&-GO:0007422-&&-peripheral nervous system development-%%-GO:0048812-&&-neuron projection morphogenesis-%%-GO:0007417-&&-central nervous system development-%%-GO:0006682-&&-galactosylceramide biosynthetic process-%%-GO:0002175-&&-protein localization to paranode region of axon-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0030913-&&-paranodal junction assembly|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015020-&&-glucuronosyltransferase activity-%%-GO:0047263-&&-N-acylsphingosine galactosyltransferase activity-%%-GO:0008489-&&-UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	G:9606:UGT8			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism-%%-hsa00565-&&-Ether lipid metabolism	UGT8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UGT8	0.33544739	0.14285714	8	4	FALSE	UGT8	UGT8	109.25	0	8	0	0.66981776	FALSE	0	UGT8	6380	0.15017241
789006	taxon:9606	2.86576335	1.03E-05	176404	1902	NPR3 like, GATOR1 complex subunit	gene	biological_process-&-1&-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0003281-&&-ventricular septum development-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0060021-&&-palate development-%%-GO:0008150-&&-biological_process-%%-GO:0038202-&&-TORC1 signaling-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048738-&&-cardiac muscle tissue development|cellular_component-&-1&-GO:0005773-&&-vacuole-%%-GO:0005575-&&-cellular_component-%%-GO:1990130-&&-Iml1 complex|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005096-&&-GTPase activator activity	G:9606:NPRL3			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	NPRL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPRL3	0.34894717	0.10714286	8	4	FALSE	NPRL3	NPRL3	168.5	0	8	0	0.68903944	FALSE	0	NPRL3	9806	0.14803792
789044	taxon:9606	2.94595872	8.00E-06	176306	1902	frizzled class receptor 1	gene	biological_process-&-1&-GO:0060022-&&-hard palate development-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0003150-&&-muscular septum morphogenesis-%%-GO:0099054-&&-presynapse assembly-%%-GO:0044339-&&-canonical Wnt signaling pathway involved in osteoblast differentiation-%%-GO:1904953-&&-Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1904886-&&-beta-catenin destruction complex disassembly-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0042493-&&-response to drug-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0035425-&&-autocrine signaling-%%-GO:1903204-&&-negative regulation of oxidative stress-induced neuron death-%%-GO:0003149-&&-membranous septum morphogenesis-%%-GO:0090179-&&-planar cell polarity pathway involved in neural tube closure-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0035414-&&-negative regulation of catenin import into nucleus-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0030182-&&-neuron differentiation-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0044338-&&-canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation|cellular_component-&-1&-GO:1990909-&&-Wnt signalosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005925-&&-focal adhesion-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0042813-&&-Wnt-activated receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0005109-&&-frizzled binding-%%-GO:0005102-&&-receptor binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0030165-&&-PDZ domain binding	G:9606:FZD1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04916-&&-Melanogenesis-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	FZD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FZD1	0.33944807	0.10714286	8	5	FALSE	FZD1	FZD1	95.75	0	8	0	0.67567355	FALSE	0	FZD1	6770	0.13947947
789155	taxon:9606	2.84985032	9.20E-07	176091	1902	mitogen-activated protein kinase kinase kinase 6	gene	biological_process-&-1&-GO:0000186-&&-activation of MAPKK activity-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004709-&&-MAP kinase kinase kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:MAP3K6			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	MAP3K6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K6	0.35089562	0.4	8	5	FALSE	MAP3K6	MAP3K6	231.5	0	7	0	0.69169161	FALSE	1	MAP3K6	2106	0.19788993
789292	taxon:9606	2.6848905	6.38E-06	175815	1902	fatty acid desaturase 2	gene	biological_process-&-1&-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0006636-&&-unsaturated fatty acid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0043651-&&-linoleic acid metabolic process|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0016213-&&-linoleoyl-CoA desaturase activity-%%-GO:0004768-&&-stearoyl-CoA 9-desaturase activity	G:9606:FADS2	FADS2	TRUE	KEGG-&-1&-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01040-&&-Biosynthesis of unsaturated fatty acids-%%-hsa01212-&&-Fatty acid metabolism	FADS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FADS2	0.37245467	0.10714286	8	4	FALSE	FADS2	FADS2	356.625	0	8	0	0.71918492	FALSE	0	FADS2	15266	0.16701828
789376	taxon:9606	2.99700646	5.28E-06	175635	1902	zinc finger MYM-type containing 6	gene	biological_process-&-1&-GO:0007010-&&-cytoskeleton organization-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding	G:9606:ZMYM6				ZMYM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMYM6	0.33366628	0	8	5	FALSE	ZMYM6	ZMYM6	72.625	0	8	0	0.66716559	FALSE	0	ZMYM6	4668	0.13539698
789509	taxon:9606	2.96502285	3.30E-06	175310	1902	growth regulation by estrogen in breast cancer 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:GREB1				GREB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GREB1	0.33726553	0.03571429	8	4	FALSE	GREB1	GREB1	94.875	0	8	0	0.67249619	FALSE	0	GREB1	5972	0.15132637
789589	taxon:9606	2.80904364	5.05E-06	175117	1902	small G protein signaling modulator 2	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0034499-&&-late endosome to Golgi transport-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005737-&&-cytoplasm-%%-GO:0042470-&&-melanosome|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding	G:9606:SGSM2				SGSM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGSM2	0.35599305	0.07142857	8	5	FALSE	SGSM2	SGSM2	198.75	0	8	0	0.69849273	FALSE	0	SGSM2	6682	0.14491959
789597	taxon:9606	2.96911927	3.63E-06	175098	1902	zinc finger and BTB domain containing 5	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZBTB5				ZBTB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB5	0.33680021	0	8	5	FALSE	ZBTB5	ZBTB5	87.5	0	8	0	0.67181346	FALSE	0	ZBTB5	4194	0.13600629
789638	taxon:9606	2.8276351	8.20E-07	174993	1902	Kruppel like factor 2	gene	biological_process-&-1&-GO:1901653-&&-cellular response to peptide-%%-GO:0040029-&&-regulation of gene expression, epigenetic-%%-GO:0071499-&&-cellular response to laminar fluid shear stress-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0060509-&&-Type I pneumocyte differentiation-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0043249-&&-erythrocyte maturation-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0071409-&&-cellular response to cycloheximide-%%-GO:0036003-&&-positive regulation of transcription from RNA polymerase II promoter in response to stress-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0000902-&&-cell morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:KLF2			KEGG-&-1&-hsa04068-&&-FoxO signaling pathway-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04371-&&-Apelin signaling pathway	KLF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF2	0.35365242	0.21428571	8	5	FALSE	KLF2	KLF2	242.25	0	8	0	0.69539415	FALSE	0	KLF2	2674	0.18582118
789687	taxon:9606	2.92232551	5.65E-06	174895	1902	homeobox B13	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0008544-&&-epidermis development-%%-GO:0009611-&&-response to wounding-%%-GO:0001525-&&-angiogenesis-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0060743-&&-epithelial cell maturation involved in prostate gland development-%%-GO:0033574-&&-response to testosterone-%%-GO:0060527-&&-prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005667-&&-transcription factor complex|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXB13				HOXB13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB13	0.34219323	0.10714286	8	5	FALSE	HOXB13	HOXB13	160.5	0	8	0	0.67961242	FALSE	0	HOXB13	10012	0.16541839
789724	taxon:9606	3.12872223	3.27E-04	174817	1902	collectin subfamily member 10	gene	biological_process-&-1&-GO:0006956-&&-complement activation-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005581-&&-collagen trimer-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:COLEC10				COLEC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COLEC10	0.3196193	0	8	5	FALSE	COLEC10	COLEC10	37.25	0	8	0	0.64521296	FALSE	0	COLEC10	313716	0.1285461
789879	taxon:9606	2.71876477	1.10E-05	174449	1902	amyloid beta precursor protein binding family B member 3	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008134-&&-transcription factor binding-%%-GO:0001540-&&-beta-amyloid binding-%%-GO:0005515-&&-protein binding	G:9606:APBB3				APBB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBB3	0.36781409	0.10714286	8	5	FALSE	APBB3	APBB3	288.625	0	8	0	0.7135392	FALSE	0	APBB3	15332	0.15219113
789880	taxon:9606	2.85284386	1.27E-06	174447	1902	cyclin O	gene	biological_process-&-1&-GO:1903251-&&-multi-ciliated epithelial cell differentiation-%%-GO:0060271-&&-cilium assembly-%%-GO:0006284-&&-base-excision repair-%%-GO:0007049-&&-cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004844-&&-uracil DNA N-glycosylase activity	G:9606:CCNO				CCNO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNO	0.35052742	0.33333333	8	5	FALSE	CCNO	CCNO	239.1666667	0	7	0	0.69119269	FALSE	1	CCNO	2930	0.20375107
789917	taxon:9606	2.87301087	7.80E-07	157981	1902	POTE ankyrin domain family member K, pseudogene	gene	biological_process-&-1&-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:POTEKP				POTEKP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POTEKP	0.3480669	0.07142857	8	5	FALSE	POTEKP	POTEKP	160.375	0	8	0	0.68783152	FALSE	0	POTEKP	2656	0.15863952
789994	taxon:9606	3.05734993	2.12E-06	174171	1902	cordon-bleu WH2 repeat protein like 1	gene	biological_process-&-1&-GO:0051639-&&-actin filament network formation-%%-GO:0030041-&&-actin filament polymerization|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0045296-&&-cadherin binding	G:9606:COBLL1				COBLL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COBLL1	0.32708065	0.03571429	8	5	FALSE	COBLL1	COBLL1	54.125	0	8	0	0.65710835	FALSE	0	COBLL1	2190	0.13685897
790048	taxon:9606	2.95525445	1.16E-06	174007	1902	3-hydroxyisobutyrate dehydrogenase	gene	biological_process-&-1&-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006574-&&-valine catabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0051287-&&-NAD binding-%%-GO:0008442-&&-3-hydroxyisobutyrate dehydrogenase activity-%%-GO:0004616-&&-phosphogluconate dehydrogenase (decarboxylating) activity	G:9606:HIBADH			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation	HIBADH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIBADH	0.33838034	0.13333333	8	5	FALSE	HIBADH	HIBADH	124.8333333	0	7	0	0.67412426	FALSE	1	HIBADH	2070	0.1833825
790097	taxon:9606	2.96817394	5.39E-06	173879	1902	megalencephalic leukoencephalopathy with subcortical cysts 1	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0006811-&&-ion transport-%%-GO:0015031-&&-protein transport-%%-GO:0071397-&&-cellular response to cholesterol-%%-GO:0032388-&&-positive regulation of intracellular transport-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0051259-&&-protein oligomerization-%%-GO:0072584-&&-caveolin-mediated endocytosis-%%-GO:0047484-&&-regulation of response to osmotic stress|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005769-&&-early endosome-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0045121-&&-membrane raft-%%-GO:0005768-&&-endosome-%%-GO:0005901-&&-caveola-%%-GO:0005764-&&-lysosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0055037-&&-recycling endosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0005215-&&-transporter activity-%%-GO:0032403-&&-protein complex binding	G:9606:MLC1				MLC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MLC1	0.33690748	0.03571429	8	5	FALSE	MLC1	MLC1	84	0	8	0	0.67197101	FALSE	0	MLC1	5586	0.13921405
790127	taxon:9606	2.85000788	3.37E-06	173812	1902	Rho guanine nucleotide exchange factor 15	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0050790-&&-regulation of catalytic activity-%%-GO:2000297-&&-negative regulation of synapse maturation-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0061299-&&-retina vasculature morphogenesis in camera-type eye-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0030425-&&-dendrite-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ARHGEF15				ARHGEF15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGEF15	0.35087622	0.07142857	8	4	FALSE	ARHGEF15	ARHGEF15	165.375	0	8	0	0.69166535	FALSE	0	ARHGEF15	4892	0.14287262
790144	taxon:9606	2.95147314	9.83E-06	173776	1902	dickkopf WNT signaling pathway inhibitor 1	gene	biological_process-&-1&-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0090244-&&-Wnt signaling pathway involved in somitogenesis-%%-GO:0001707-&&-mesoderm formation-%%-GO:1904723-&&-negative regulation of Wnt-Frizzled-LRP5/6 complex assembly-%%-GO:0042663-&&-regulation of endodermal cell fate specification-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0050807-&&-regulation of synapse organization-%%-GO:0060325-&&-face morphogenesis-%%-GO:2000726-&&-negative regulation of cardiac muscle cell differentiation-%%-GO:0000904-&&-cell morphogenesis involved in differentiation-%%-GO:0001706-&&-endoderm formation-%%-GO:0042662-&&-negative regulation of mesodermal cell fate specification-%%-GO:0098883-&&-synapse disassembly-%%-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0002090-&&-regulation of receptor internalization-%%-GO:0090082-&&-positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0061743-&&-motor learning-%%-GO:0030900-&&-forebrain development-%%-GO:1900116-&&-extracellular negative regulation of signal transduction-%%-GO:1904958-&&-positive regulation of midbrain dopaminergic neuron differentiation-%%-GO:0001942-&&-hair follicle development-%%-GO:0033137-&&-negative regulation of peptidyl-serine phosphorylation-%%-GO:1901296-&&-negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0048642-&&-negative regulation of skeletal muscle tissue development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:1904338-&&-regulation of dopaminergic neuron differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0031901-&&-early endosome membrane|molecular_function-&-1&-GO:0048019-&&-receptor antagonist activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0039706-&&-co-receptor binding-%%-GO:0050750-&&-low-density lipoprotein particle receptor binding-%%-GO:0004871-&&-signal transducer activity	G:9606:DKK1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	DKK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DKK1	0.33881386	0.07142857	8	5	FALSE	DKK1	DKK1	87.375	0	8	0	0.67475448	FALSE	0	DKK1	10028	0.14650084
790177	taxon:9606	2.890657	8.89E-06	173710	1902	PDZ domain containing 2	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region	G:9606:PDZD2				PDZD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDZD2	0.34594212	0.10714286	8	4	FALSE	PDZD2	PDZD2	147	0	8	0	0.6848905	FALSE	0	PDZD2	8880	0.1450495
790246	taxon:9606	2.77060028	1.40E-07	173534	1902	zinc finger CCHC-type containing 11	gene	biological_process-&-1&-GO:0010586-&&-miRNA metabolic process-%%-GO:0071044-&&-histone mRNA catabolic process-%%-GO:0010587-&&-miRNA catabolic process-%%-GO:0031123-&&-RNA 3'-end processing-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0031054-&&-pre-miRNA processing|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0050265-&&-RNA uridylyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:ZCCHC11				ZCCHC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZCCHC11	0.36093261	0.71428571	8	4	FALSE	ZCCHC11	ZCCHC11	430.125	0	8	0	0.70489995	FALSE	0	ZCCHC11	1158	0.26782379
790314	taxon:9606	2.83031353	3.52E-06	173347	1902	mitochondrial pyruvate carrier 2	gene	biological_process-&-1&-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:1902361-&&-mitochondrial pyruvate transmembrane transport-%%-GO:0061732-&&-mitochondrial acetyl-CoA biosynthetic process from pyruvate|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031305-&&-integral component of mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0050833-&&-pyruvate transmembrane transporter activity	G:9606:MPC2				MPC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPC2	0.35331775	0.14285714	8	4	FALSE	MPC2	MPC2	204.125	0	8	0	0.69494774	FALSE	0	MPC2	9738	0.15670638
790316	taxon:9606	2.91239956	6.51E-06	173337	1902	ABI family member 3 binding protein	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005614-&&-interstitial matrix-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0008201-&&-heparin binding	G:9606:ABI3BP				ABI3BP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ABI3BP	0.34335948	0.07142857	8	5	FALSE	ABI3BP	ABI3BP	121.875	0	8	0	0.68126674	FALSE	0	ABI3BP	6226	0.13904817
790405	taxon:9606	2.71892233	6.79E-06	173101	1902	serum/glucocorticoid regulated kinase family member 3	gene	biological_process-&-1&-GO:0042127-&&-regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0006950-&&-response to stress-%%-GO:0032411-&&-positive regulation of transporter activity|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0005769-&&-early endosome-%%-GO:0005829-&&-cytosol-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0017081-&&-chloride channel regulator activity-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0035091-&&-phosphatidylinositol binding	G:9606:SGK3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04068-&&-FoxO signaling pathway	SGK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SGK3	0.36779278	0.07142857	8	5	FALSE	SGK3	SGK3	292.375	0	8	0	0.71351295	FALSE	0	SGK3	14524	0.15525266
790455	taxon:9606	2.87301087	7.80E-07	156416	1902	POTE ankyrin domain family member M	gene		G:9606:POTEM				POTEM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POTEM	0.3480669	0.07142857	8	5	FALSE	POTEM	POTEM	160.375	0	8	0	0.68783152	FALSE	0	POTEM	2656	0.15863952
790589	taxon:9606	2.91933197	1.94E-06	172057	1902	dickkopf WNT signaling pathway inhibitor 3	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:2000065-&&-negative regulation of cortisol biosynthetic process-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030325-&&-adrenal gland development-%%-GO:0032348-&&-negative regulation of aldosterone biosynthetic process-%%-GO:1902613-&&-negative regulation of anti-Mullerian hormone signaling pathway-%%-GO:0017015-&&-regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space	G:9606:DKK3				DKK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DKK3	0.34254412	0.03571429	8	5	FALSE	DKK3	DKK3	129.625	0	8	0	0.68011134	FALSE	0	DKK3	4282	0.15659174
790622	taxon:9606	3.00945329	0	171728	1902	COMM domain containing 10	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COMMD10				COMMD10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD10	0.33228627	1	8	4	FALSE	COMMD10	COMMD10	84	0	8	0	0.66509112	FALSE	0	COMMD10	0	0.1826087
790669	taxon:9606	3.00945329	0	171537	1902	COMM domain containing 5	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COMMD5				COMMD5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COMMD5	0.33228627	1	8	4	FALSE	COMMD5	COMMD5	84	0	8	0	0.66509112	FALSE	0	COMMD5	0	0.1826087
790723	taxon:9606	2.77343627	9.50E-07	171384	1902	kelch like family member 5	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL5				KLHL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL5	0.36056354	0.25	8	4	FALSE	KLHL5	KLHL5	314	0	8	0	0.70442729	FALSE	0	KLHL5	4080	0.19415223
790729	taxon:9606	2.95541201	2.55E-06	171371	1902	mitochondrial trans-2-enoyl-CoA reductase	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0019166-&&-trans-2-enoyl-CoA reductase (NADPH) activity	G:9606:MECR			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00062-&&-Fatty acid elongation-%%-hsa01212-&&-Fatty acid metabolism	MECR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MECR	0.3383623	0.14285714	8	4	FALSE	MECR	MECR	105.75	0	8	0	0.674098	FALSE	0	MECR	3216	0.16445313
790783	taxon:9606	2.97274303	2.59E-06	171221	1902	guanosine monophosphate reductase 2	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006144-&&-purine nucleobase metabolic process-%%-GO:0043101-&&-purine-containing compound salvage-%%-GO:0046037-&&-GMP metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:1902560-&&-GMP reductase complex|molecular_function-&-1&-GO:0003920-&&-GMP reductase activity-%%-GO:0046872-&&-metal ion binding	G:9606:GMPR2			KEGG-&-1&-hsa00230-&&-Purine metabolism	GMPR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GMPR2	0.33638965	0.06666667	8	5	FALSE	GMPR2	GMPR2	115	0	7	0	0.6712095	FALSE	1	GMPR2	3364	0.1844086
790863	taxon:9606	2.77154561	2.12E-06	170854	1902	F-box protein 42	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FBXO42				FBXO42	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO42	0.3608095	0.42857143	8	4	FALSE	FBXO42	FBXO42	305.875	0	8	0	0.7047424	FALSE	0	FBXO42	3278	0.18415111
790892	taxon:9606	2.76697652	5.31E-06	170753	1902	TP53 regulated inhibitor of apoptosis 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:2001140-&&-positive regulation of phospholipid transport-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0015914-&&-phospholipid transport-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0090201-&&-negative regulation of release of cytochrome c from mitochondria-%%-GO:0030330-&&-DNA damage response, signal transduction by p53 class mediator-%%-GO:0097035-&&-regulation of membrane lipid distribution-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0034644-&&-cellular response to UV-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:1990050-&&-phosphatidic acid transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0002039-&&-p53 binding	G:9606:TRIAP1				TRIAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIAP1	0.36140531	0.17857143	8	4	FALSE	TRIAP1	TRIAP1	247.25	0	8	0	0.70550391	FALSE	0	TRIAP1	10084	0.15389408
790994	taxon:9606	2.71986765	1.42E-05	170471	1902	misato 1, mitochondrial distribution and morphology regulator	gene	biological_process-&-1&-GO:0007005-&&-mitochondrion organization-%%-GO:0048311-&&-mitochondrion distribution|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0003924-&&-GTPase activity	G:9606:MSTO1				MSTO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MSTO1	0.36766495	0.03571429	8	4	FALSE	MSTO1	MSTO1	261.375	0	8	0	0.71335539	FALSE	0	MSTO1	18304	0.13702681
791058	taxon:9606	3.01386482	3.74E-06	170201	1902	intelectin 1	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0009624-&&-response to nematode|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031526-&&-brush border membrane-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043235-&&-receptor complex-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0070492-&&-oligosaccharide binding	G:9606:ITLN1				ITLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITLN1	0.33179988	0	8	5	FALSE	ITLN1	ITLN1	76.83333333	0	7	0	0.66435586	FALSE	1	ITLN1	2504	0.17473118
791082	taxon:9606	2.95163069	5.97E-06	170119	1902	transmembrane protein 57	gene	biological_process-&-1&-GO:0007420-&&-brain development-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0044306-&&-neuron projection terminus-%%-GO:0045202-&&-synapse-%%-GO:0030424-&&-axon-%%-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TMEM57				TMEM57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM57	0.33879577	0.03571429	8	5	FALSE	TMEM57	TMEM57	104.125	0	8	0	0.67472822	FALSE	0	TMEM57	7034	0.13875839
791109	taxon:9606	2.84433591	5.12E-06	170016	1902	GTPase, IMAP family member 5	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005764-&&-lysosome-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:GIMAP5				GIMAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIMAP5	0.35157592	0.5	8	4	FALSE	GIMAP5	GIMAP5	182.75	0	8	0	0.69261068	FALSE	0	GIMAP5	8534	0.14727823
791178	taxon:9606	2.81676383	3.33E-05	169805	1902	chromosome 1 open reading frame 112	gene		G:9606:C1orf112				C1orf112	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1orf112	0.35501734	0.03571429	8	5	FALSE	C1orf112	C1orf112	187.875	0	8	0	0.69720603	FALSE	0	C1orf112	28862	0.13433238
791229	taxon:9606	2.78556798	1.18E-06	169653	1902	myeloid derived growth factor	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0001525-&&-angiogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MYDGF				MYDGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYDGF	0.35899321	0.10714286	8	5	FALSE	MYDGF	MYDGF	252.125	0	8	0	0.70240534	FALSE	0	MYDGF	4642	0.16990209
791231	taxon:9606	2.94769182	7.15E-06	169650	1902	platelet derived growth factor C	gene	biological_process-&-1&-GO:0009790-&&-embryo development-%%-GO:0007596-&&-blood coagulation-%%-GO:0071230-&&-cellular response to amino acid stimulus-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0060348-&&-bone development-%%-GO:0048565-&&-digestive tract development-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0007417-&&-central nervous system development-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0048008-&&-platelet-derived growth factor receptor signaling pathway-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0051781-&&-positive regulation of cell division|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005161-&&-platelet-derived growth factor receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity	G:9606:PDGFC			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05215-&&-Prostate cancer-%%-hsa05231-&&-Choline metabolism in cancer-%%-hsa04540-&&-Gap junction-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04510-&&-Focal adhesion-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	PDGFC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDGFC	0.33924849	0.10714286	8	4	FALSE	PDGFC	PDGFC	90.625	0	8	0	0.6753847	FALSE	0	PDGFC	6496	0.13927469
791262	taxon:9606	2.82637467	2.61E-06	169466	1902	NDRG family member 2	gene	biological_process-&-1&-GO:0001818-&&-negative regulation of cytokine production-%%-GO:0010574-&&-regulation of vascular endothelial growth factor production-%%-GO:0021762-&&-substantia nigra development-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0090361-&&-regulation of platelet-derived growth factor production-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030154-&&-cell differentiation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030426-&&-growth cone-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:NDRG2				NDRG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NDRG2	0.35381013	0.03571429	8	4	FALSE	NDRG2	NDRG2	186.875	0	8	0	0.69560422	FALSE	0	NDRG2	4988	0.14878098
791325	taxon:9606	2.77343627	2.25E-06	169163	1902	TP53 induced glycolysis regulatory phosphatase	gene	biological_process-&-1&-GO:0006003-&&-fructose 2,6-bisphosphate metabolic process-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0006915-&&-apoptotic process-%%-GO:2000378-&&-negative regulation of reactive oxygen species metabolic process-%%-GO:0030388-&&-fructose 1,6-bisphosphate metabolic process-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:0060576-&&-intestinal epithelial cell development-%%-GO:0071279-&&-cellular response to cobalt ion-%%-GO:0002931-&&-response to ischemia-%%-GO:0010332-&&-response to gamma radiation-%%-GO:0009410-&&-response to xenobiotic stimulus-%%-GO:0016311-&&-dephosphorylation-%%-GO:0043456-&&-regulation of pentose-phosphate shunt-%%-GO:1903301-&&-positive regulation of hexokinase activity-%%-GO:1902153-&&-regulation of response to DNA damage checkpoint signaling-%%-GO:0045820-&&-negative regulation of glycolytic process-%%-GO:0010666-&&-positive regulation of cardiac muscle cell apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:1904024-&&-negative regulation of glucose catabolic process to lactate via pyruvate-%%-GO:0006914-&&-autophagy-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1901525-&&-negative regulation of macromitophagy|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004331-&&-fructose-2,6-bisphosphate 2-phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004083-&&-bisphosphoglycerate 2-phosphatase activity	G:9606:TIGAR			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa05230-&&-Central carbon metabolism in cancer	TIGAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIGAR	0.36056354	0.10714286	8	4	FALSE	TIGAR	TIGAR	230.75	0	8	0	0.70442729	FALSE	0	TIGAR	4972	0.14816602
791326	taxon:9606	2.83661572	3.63E-06	169162	1902	patatin like phospholipase domain containing 2	gene	biological_process-&-1&-GO:0010891-&&-negative regulation of sequestering of triglyceride-%%-GO:0010898-&&-positive regulation of triglyceride catabolic process-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0034389-&&-lipid particle organization-%%-GO:0019915-&&-lipid storage-%%-GO:0036155-&&-acylglycerol acyl-chain remodeling-%%-GO:0055088-&&-lipid homeostasis|cellular_component-&-1&-GO:0005811-&&-lipid particle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004806-&&-triglyceride lipase activity-%%-GO:0016411-&&-acylglycerol O-acyltransferase activity-%%-GO:0004465-&&-lipoprotein lipase activity	G:9606:PNPLA2	PNPLA2	TRUE	KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways	PNPLA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PNPLA2	0.35253277	0.14285714	8	5	FALSE	PNPLA2	PNPLA2	176.75	0	8	0	0.69389738	FALSE	0	PNPLA2	4622	0.13964766
791372	taxon:9606	2.93540255	3.40E-06	168917	1902	spectrin beta, non-erythrocytic 4	gene	biological_process-&-1&-GO:0090002-&&-establishment of protein localization to plasma membrane-%%-GO:0007411-&&-axon guidance-%%-GO:0007409-&&-axonogenesis-%%-GO:0051693-&&-actin filament capping-%%-GO:0061337-&&-cardiac conduction-%%-GO:0019226-&&-transmission of nerve impulse-%%-GO:0033135-&&-regulation of peptidyl-serine phosphorylation-%%-GO:0009566-&&-fertilization-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0010459-&&-negative regulation of heart rate-%%-GO:0021952-&&-central nervous system projection neuron axonogenesis-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0002028-&&-regulation of sodium ion transport-%%-GO:0007628-&&-adult walking behavior-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045162-&&-clustering of voltage-gated sodium channels-%%-GO:0007016-&&-cytoskeletal anchoring at plasma membrane-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport|cellular_component-&-1&-GO:0008091-&&-spectrin-%%-GO:0016605-&&-PML body-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016363-&&-nuclear matrix-%%-GO:0043194-&&-axon initial segment-%%-GO:0033270-&&-paranode region of axon-%%-GO:0005829-&&-cytosol-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0033268-&&-node of Ranvier-%%-GO:0070852-&&-cell body fiber-%%-GO:0016020-&&-membrane-%%-GO:0043203-&&-axon hillock-%%-GO:0005912-&&-adherens junction|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0030506-&&-ankyrin binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0030507-&&-spectrin binding-%%-GO:0003779-&&-actin binding-%%-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0019902-&&-phosphatase binding	G:9606:SPTBN4				SPTBN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPTBN4	0.34066878	0.07142857	8	4	FALSE	SPTBN4	SPTBN4	113.625	0	8	0	0.67743291	FALSE	0	SPTBN4	4448	0.15046605
791412	taxon:9606	3.01733102	2.33E-05	168747	1902	fibronectin type III domain containing 4	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane	G:9606:FNDC4				FNDC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FNDC4	0.33141872	0.07142857	8	5	FALSE	FNDC4	FNDC4	68.5	0	8	0	0.66377816	FALSE	0	FNDC4	34292	0.14723427
791417	taxon:9606	2.79439105	4.56E-06	168731	1902	pleckstrin homology and RhoGEF domain containing G2	gene	biological_process-&-1&-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:PLEKHG2				PLEKHG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLEKHG2	0.35785972	0.03571429	8	4	FALSE	PLEKHG2	PLEKHG2	214.625	0	8	0	0.70093482	FALSE	0	PLEKHG2	8596	0.14539429
791450	taxon:9606	2.69607689	6.13E-06	168589	1902	CaM kinase like vesicle associated	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0030659-&&-cytoplasmic vesicle membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity	G:9606:CAMKV				CAMKV	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMKV	0.3709093	0.17857143	8	4	FALSE	CAMKV	CAMKV	319.375	0	8	0	0.71732052	FALSE	0	CAMKV	11148	0.15820119
791505	taxon:9606	2.70316685	4.17E-06	168352	1902	Rho GTPase activating protein 9	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0007165-&&-signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0034774-&&-secretory granule lumen|molecular_function-&-1&-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:ARHGAP9				ARHGAP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP9	0.36993647	0.25	8	4	FALSE	ARHGAP9	ARHGAP9	306	0	8	0	0.71613886	FALSE	0	ARHGAP9	10580	0.15481013
791563	taxon:9606	3.01512526	2.10E-06	168016	1902	transmembrane protein 62	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0016787-&&-hydrolase activity	G:9606:TMEM62				TMEM62	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM62	0.33166118	0.03571429	8	5	FALSE	TMEM62	TMEM62	64.625	0	8	0	0.66414579	FALSE	0	TMEM62	2130	0.1478588
791584	taxon:9606	3.04868442	1.25E-05	167927	1902	TM2 domain containing 3	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TM2D3				TM2D3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TM2D3	0.32801034	0	8	5	FALSE	TM2D3	TM2D3	59	0	8	0	0.6585526	FALSE	0	TM2D3	8892	0.13092551
791610	taxon:9606	2.76067433	6.25E-06	167821	1902	kelch like family member 36	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL36				KLHL36	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL36	0.36223034	0.14285714	8	4	FALSE	KLHL36	KLHL36	296.25	0	8	0	0.70655428	FALSE	0	KLHL36	8726	0.17611607
791614	taxon:9606	2.84181503	6.94E-06	167805	1902	glutathione S-transferase C-terminal domain containing	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:GSTCD				GSTCD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTCD	0.35188779	0.03571429	8	4	FALSE	GSTCD	GSTCD	178.625	0	8	0	0.69303083	FALSE	0	GSTCD	9920	0.14252804
791623	taxon:9606	2.68552072	3.75E-06	167761	1902	NIMA related kinase 11	gene	biological_process-&-1&-GO:0031573-&&-intra-S DNA damage checkpoint-%%-GO:1901990-&&-regulation of mitotic cell cycle phase transition-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0044772-&&-mitotic cell cycle phase transition-%%-GO:0031572-&&-G2 DNA damage checkpoint-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0016572-&&-histone phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:NEK11				NEK11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK11	0.37236726	0.06666667	8	4	FALSE	NEK11	NEK11	412.6666667	0	7	0	0.71907988	FALSE	1	NEK11	9938	0.19703491
791639	taxon:9606	3.02851741	2.02E-05	167702	1902	KIAA0319 like	gene	cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KIAA0319L				KIAA0319L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA0319L	0.33019457	0	8	5	FALSE	KIAA0319L	KIAA0319L	83.125	0	8	0	0.66191377	FALSE	0	KIAA0319L	16386	0.16071429
791646	taxon:9606	2.83992437	2.46E-06	167592	1902	actin like 8	gene	biological_process-&-1&-GO:0030855-&&-epithelial cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ACTL8				ACTL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACTL8	0.35212205	0.21428571	8	4	FALSE	ACTL8	ACTL8	207.75	0	8	0	0.69334594	FALSE	0	ACTL8	4530	0.15587462
791666	taxon:9606	3.18087285	8.58E-06	167528	1902	wntless Wnt ligand secretion mediator	gene	biological_process-&-1&-GO:0030902-&&-hindbrain development-%%-GO:0001707-&&-mesoderm formation-%%-GO:0061355-&&-Wnt protein secretion-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0031017-&&-exocrine pancreas development-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0030177-&&-positive regulation of Wnt signaling pathway-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0030901-&&-midbrain development-%%-GO:0061357-&&-positive regulation of Wnt protein secretion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0031901-&&-early endosome membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0032839-&&-dendrite cytoplasm-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005769-&&-early endosome-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0032590-&&-dendrite membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding-%%-GO:0031852-&&-mu-type opioid receptor binding	G:9606:WLS				WLS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WLS	0.31437912	0.10714286	8	5	FALSE	WLS	WLS	54.875	0	8	0	0.63652119	FALSE	0	WLS	7354	0.16978193
791668	taxon:9606	2.78367733	9.13E-06	167520	1902	premature ovarian failure, 1B	gene	cellular_component-&-1&-GO:0030057-&&-desmosome-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0003779-&&-actin binding	G:9606:POF1B				POF1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POF1B	0.35923704	0.14285714	8	4	FALSE	POF1B	POF1B	261.375	0	8	0	0.70272045	FALSE	0	POF1B	12416	0.17219472
791694	taxon:9606	2.94265007	1.05E-06	167402	1902	dual specificity phosphatase 16	gene	biological_process-&-1&-GO:0045204-&&-MAPK export from nucleus-%%-GO:0045209-&&-MAPK phosphatase export from nucleus, leptomycin B sensitive-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0016311-&&-dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0016791-&&-phosphatase activity	G:9606:DUSP16			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP16	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP16	0.33982974	0.42857143	8	5	FALSE	DUSP16	DUSP16	129.5	0	8	0	0.67622499	FALSE	0	DUSP16	2054	0.18086592
791708	taxon:9606	2.85757051	3.57E-06	167283	1902	kin of IRRE like 2 (Drosophila)	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0001933-&&-negative regulation of protein phosphorylation|cellular_component-&-1&-GO:0036057-&&-slit diaphragm-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:KIRREL2				KIRREL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIRREL2	0.34994762	0.03571429	8	5	FALSE	KIRREL2	KIRREL2	157.75	0	8	0	0.69040492	FALSE	0	KIRREL2	4948	0.14741784
791734	taxon:9606	2.87947062	5.69E-06	167130	1902	AMMECR1 like	gene		G:9606:AMMECR1L				AMMECR1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMMECR1L	0.34728606	0.14285714	8	5	FALSE	AMMECR1L	AMMECR1L	152.125	0	8	0	0.6867549	FALSE	0	AMMECR1L	6178	0.15054563
791754	taxon:9606	2.95147314	2.77E-06	167033	1902	HOP homeobox	gene	biological_process-&-1&-GO:0001829-&&-trophectodermal cell differentiation-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:HOPX				HOPX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOPX	0.33881386	0.07142857	8	4	FALSE	HOPX	HOPX	95.625	0	8	0	0.67475448	FALSE	0	HOPX	3550	0.14412879
791772	taxon:9606	2.86749646	1.80E-06	166944	1902	GTF2I repeat domain containing 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:GTF2IRD2				GTF2IRD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTF2IRD2	0.34873626	0.39285714	8	5	FALSE	GTF2IRD2	GTF2IRD2	175.125	0	8	0	0.68875059	FALSE	0	GTF2IRD2	3554	0.16459117
791809	taxon:9606	2.9683315	6.32E-06	166778	1902	phytanoyl-CoA 2-hydroxylase interacting protein like	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005739-&&-mitochondrion	G:9606:PHYHIPL				PHYHIPL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHYHIPL	0.3368896	0.2	8	5	FALSE	PHYHIPL	PHYHIPL	113.5	0	7	0	0.67194475	FALSE	1	PHYHIPL	4334	0.18646865
791822	taxon:9606	2.71829211	4.41E-06	166688	1902	glutamic--pyruvic transaminase 2	gene	biological_process-&-1&-GO:0042853-&&-L-alanine catabolic process-%%-GO:0006103-&&-2-oxoglutarate metabolic process-%%-GO:0008652-&&-cellular amino acid biosynthetic process-%%-GO:0042851-&&-L-alanine metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0004021-&&-L-alanine:2-oxoglutarate aminotransferase activity-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:GPT2			KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00220-&&-Arginine biosynthesis-%%-hsa01230-&&-Biosynthesis of amino acids-%%-hsa01210-&&-2-Oxocarboxylic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism	GPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPT2	0.36787805	0.14285714	8	4	FALSE	GPT2	GPT2	288.125	0	8	0	0.71361798	FALSE	0	GPT2	7906	0.15010433
791851	taxon:9606	2.83897905	3.80E-06	166589	1902	ATPase family, AAA domain containing 1	gene	biological_process-&-1&-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0051967-&&-negative regulation of synaptic transmission, glutamatergic-%%-GO:0007612-&&-learning-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0007613-&&-memory|cellular_component-&-1&-GO:0045211-&&-postsynaptic membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005739-&&-mitochondrion-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008568-&&-microtubule-severing ATPase activity	G:9606:ATAD1				ATAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATAD1	0.3522393	0.17857143	8	4	FALSE	ATAD1	ATAD1	194.25	0	8	0	0.69350349	FALSE	0	ATAD1	7684	0.15480463
791853	taxon:9606	2.7976997	6.48E-06	166591	1902	leucine rich repeat and Ig domain containing 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007409-&&-axonogenesis-%%-GO:0050771-&&-negative regulation of axonogenesis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005515-&&-protein binding	G:9606:LINGO1				LINGO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LINGO1	0.3574365	0.03571429	8	5	FALSE	LINGO1	LINGO1	199	0	8	0	0.70038338	FALSE	0	LINGO1	8384	0.13990826
791860	taxon:9606	2.81786671	2.13E-06	182964	1902	acyl-CoA dehydrogenase, short/branched chain	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003995-&&-acyl-CoA dehydrogenase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:ACADSB			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	ACADSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACADSB	0.35487839	0.10714286	8	4	FALSE	ACADSB	ACADSB	201	0	8	0	0.69702222	FALSE	0	ACADSB	5654	0.15029985
791871	taxon:9606	2.87852529	4.93E-06	166570	1902	protein phosphatase 1 regulatory subunit 15B	gene	biological_process-&-1&-GO:0042542-&&-response to hydrogen peroxide-%%-GO:1903912-&&-negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation-%%-GO:0070262-&&-peptidyl-serine dephosphorylation-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:1903898-&&-negative regulation of PERK-mediated unfolded protein response-%%-GO:0006983-&&-ER overload response|cellular_component-&-1&-GO:0000164-&&-protein phosphatase type 1 complex|molecular_function-&-1&-GO:0004722-&&-protein serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PPP1R15B				PPP1R15B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP1R15B	0.34740011	0.17857143	8	4	FALSE	PPP1R15B	PPP1R15B	180.375	0	8	0	0.68691245	FALSE	0	PPP1R15B	6698	0.17964072
791879	taxon:9606	2.85552229	2.35E-06	182932	1902	poly(ADP-ribose) polymerase family member 4	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0008219-&&-cell death-%%-GO:0006281-&&-DNA repair-%%-GO:0006954-&&-inflammatory response-%%-GO:0042493-&&-response to drug-%%-GO:0006464-&&-cellular protein modification process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006471-&&-protein ADP-ribosylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus-%%-GO:0030529-&&-intracellular ribonucleoprotein complex-%%-GO:0005876-&&-spindle microtubule|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003950-&&-NAD+ ADP-ribosyltransferase activity-%%-GO:0019899-&&-enzyme binding	G:9606:PARP4			KEGG-&-1&-hsa03410-&&-Base excision repair-%%-hsa04210-&&-Apoptosis-%%-hsa04217-&&-Necroptosis	PARP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PARP4	0.35019863	0.28571429	8	4	FALSE	PARP4	PARP4	180.25	0	8	0	0.69074628	FALSE	0	PARP4	3594	0.16011111
791886	taxon:9606	2.96092642	2.53E-06	182921	1902	adrenoceptor beta 3	gene	biological_process-&-1&-GO:0009409-&&-response to cold-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0002032-&&-desensitization of G-protein coupled receptor protein signaling pathway by arrestin-%%-GO:0031649-&&-heat generation-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0007568-&&-aging-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0002025-&&-vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure-%%-GO:0042755-&&-eating behavior-%%-GO:0001659-&&-temperature homeostasis-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0046677-&&-response to antibiotic-%%-GO:0040015-&&-negative regulation of multicellular organism growth|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0015052-&&-beta3-adrenergic receptor activity-%%-GO:0051379-&&-epinephrine binding-%%-GO:0004939-&&-beta-adrenergic receptor activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0031699-&&-beta-3 adrenergic receptor binding-%%-GO:0051380-&&-norepinephrine binding	G:9606:ADRB3	ADRB3	TRUE	KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	ADRB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADRB3	0.33773213	0.33333333	8	5	FALSE	ADRB3	ADRB3	130.5	0	7	0	0.67317893	FALSE	1	ADRB3	2954	0.18995633
791920	taxon:9606	2.69182291	7.11E-06	182872	1902	activated leukocyte cell adhesion molecule	gene	biological_process-&-1&-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0008045-&&-motor neuron axon guidance-%%-GO:0048846-&&-axon extension involved in axon guidance-%%-GO:0007155-&&-cell adhesion-%%-GO:0002250-&&-adaptive immune response-%%-GO:0007165-&&-signal transduction-%%-GO:1990138-&&-neuron projection extension|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0001772-&&-immunological synapse-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0042101-&&-T cell receptor complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:ALCAM			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	ALCAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALCAM	0.37149546	0.46666667	8	4	FALSE	ALCAM	ALCAM	438.5	0	7	0	0.71802952	FALSE	1	ALCAM	7240	0.20970827
791949	taxon:9606	2.9171262	1.19E-06	182813	1902	angiopoietin 2	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0014823-&&-response to activity-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0050900-&&-leukocyte migration-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0072012-&&-glomerulus vasculature development-%%-GO:0007165-&&-signal transduction-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0001525-&&-angiogenesis-%%-GO:0007281-&&-germ cell development-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0009314-&&-response to radiation-%%-GO:0001666-&&-response to hypoxia-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0050928-&&-negative regulation of positive chemotaxis-%%-GO:0009749-&&-response to glucose-%%-GO:0048014-&&-Tie signaling pathway-%%-GO:0060135-&&-maternal process involved in female pregnancy|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0046872-&&-metal ion binding	G:9606:ANGPT2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04066-&&-HIF-1 signaling pathway	ANGPT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANGPT2	0.34280313	0.13333333	8	5	FALSE	ANGPT2	ANGPT2	160	0	7	0	0.68047897	FALSE	1	ANGPT2	2398	0.20292621
791957	taxon:9606	2.87253821	1.11E-06	166426	1902	helicase with zinc finger 2	gene	biological_process-&-1&-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:HELZ2				HELZ2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HELZ2	0.34812418	0.03571429	8	5	FALSE	HELZ2	HELZ2	228.125	0	8	0	0.6879103	FALSE	0	HELZ2	3838	0.20139504
791969	taxon:9606	2.79187017	3.84E-06	182785	1902	amyloid beta precursor protein binding family A member 2	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0015031-&&-protein transport-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007399-&&-nervous system development-%%-GO:0035264-&&-multicellular organism growth|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0005515-&&-protein binding	G:9606:APBA2				APBA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APBA2	0.35818284	0.14285714	8	5	FALSE	APBA2	APBA2	207.375	0	8	0	0.70135497	FALSE	0	APBA2	6560	0.14246387
791976	taxon:9606	2.87679219	4.09E-06	166398	1902	protein serine kinase H2	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:PSKH2				PSKH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSKH2	0.3476094	0.17857143	8	5	FALSE	PSKH2	PSKH2	170.375	0	8	0	0.6872013	FALSE	0	PSKH2	4948	0.16662586
792008	taxon:9606	2.79297306	1.88E-05	182736	1902	3-hydroxybutyrate dehydrogenase 1	gene	biological_process-&-1&-GO:0046952-&&-ketone body catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0046951-&&-ketone body biosynthetic process|cellular_component-&-1&-GO:0099617-&&-matrix side of mitochondrial inner membrane-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003858-&&-3-hydroxybutyrate dehydrogenase activity	G:9606:BDH1			KEGG-&-1&-hsa00072-&&-Synthesis and degradation of ketone bodies-%%-hsa01100-&&-Metabolic pathways-%%-hsa00650-&&-Butanoate metabolism	BDH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BDH1	0.35804141	0.03571429	8	4	FALSE	BDH1	BDH1	203.375	0	8	0	0.70117116	FALSE	0	BDH1	24782	0.13831058
792028	taxon:9606	2.86623602	1.41E-05	182713	1902	bone morphogenetic protein 1	gene	biological_process-&-1&-GO:0001502-&&-cartilage condensation-%%-GO:0061036-&&-positive regulation of cartilage development-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0042157-&&-lipoprotein metabolic process-%%-GO:0001501-&&-skeletal system development-%%-GO:0007275-&&-multicellular organism development-%%-GO:0001503-&&-ossification-%%-GO:0006508-&&-proteolysis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0031982-&&-vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008233-&&-peptidase activity	G:9606:BMP1				BMP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMP1	0.34888962	0.10714286	8	4	FALSE	BMP1	BMP1	144.875	0	8	0	0.68896066	FALSE	0	BMP1	12958	0.13209058
792071	taxon:9606	3.00677485	2.33E-06	166276	1902	D-tyrosyl-tRNA deacylase 1	gene	biological_process-&-1&-GO:0006399-&&-tRNA metabolic process-%%-GO:0006260-&&-DNA replication-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0051500-&&-D-tyrosyl-tRNA(Tyr) deacylase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0002161-&&-aminoacyl-tRNA editing activity	G:9606:DTD1				DTD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTD1	0.33258227	0.10714286	8	5	FALSE	DTD1	DTD1	87.375	0	8	0	0.66553752	FALSE	0	DTD1	3152	0.16194238
792109	taxon:9606	2.95572712	4.26E-06	182599	1902	collagen type IV alpha 4 chain	gene	biological_process-&-1&-GO:0032836-&&-glomerular basement membrane development-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005587-&&-collagen type IV trimer-%%-GO:0005605-&&-basal lamina|molecular_function-&-1&-GO:0005201-&&-extracellular matrix structural constituent	G:9606:COL4A4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05146-&&-Amoebiasis-%%-hsa04510-&&-Focal adhesion-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05222-&&-Small cell lung cancer-%%-hsa05165-&&-Human papillomavirus infection	COL4A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL4A4	0.33832623	0.14285714	8	5	FALSE	COL4A4	COL4A4	103.5	0	8	0	0.67404548	FALSE	0	COL4A4	6238	0.13695219
792160	taxon:9606	2.93823854	1.29E-06	182500	1902	adenylate cyclase 5	gene	biological_process-&-1&-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0006171-&&-cAMP biosynthetic process-%%-GO:0007191-&&-adenylate cyclase-activating dopamine receptor signaling pathway-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0001973-&&-adenosine receptor signaling pathway-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:1904322-&&-cellular response to forskolin-%%-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007195-&&-adenylate cyclase-inhibiting dopamine receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005929-&&-cilium-%%-GO:0045111-&&-intermediate filament cytoskeleton|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004016-&&-adenylate cyclase activity-%%-GO:0008179-&&-adenylate cyclase binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004383-&&-guanylate cyclase activity-%%-GO:0097110-&&-scaffold protein binding	G:9606:ADCY5			KEGG-&-1&-hsa05012-&&-Parkinson disease-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa05031-&&-Amphetamine addiction-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04924-&&-Renin secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05030-&&-Cocaine addiction-%%-hsa00230-&&-Purine metabolism-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa05034-&&-Alcoholism-%%-hsa04970-&&-Salivary secretion	ADCY5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADCY5	0.34033996	0.2	8	4	FALSE	ADCY5	ADCY5	142	0	7	0	0.67696024	FALSE	1	ADCY5	2526	0.20705596
792162	taxon:9606	2.9470616	8.02E-06	182499	1902	adenylate cyclase 6	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:1904117-&&-cellular response to vasopressin-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0006171-&&-cAMP biosynthetic process-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0035811-&&-negative regulation of urine volume-%%-GO:0097746-&&-regulation of blood vessel diameter-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0071870-&&-cellular response to catecholamine stimulus-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:1904322-&&-cellular response to forskolin|cellular_component-&-1&-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005929-&&-cilium-%%-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding-%%-GO:0004016-&&-adenylate cyclase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004383-&&-guanylate cyclase activity	G:9606:ADCY6			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04742-&&-Taste transduction-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa01522-&&-Endocrine resistance-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04924-&&-Renin secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa04970-&&-Salivary secretion	ADCY6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADCY6	0.33932104	0.03571429	8	4	FALSE	ADCY6	ADCY6	95.875	0	8	0	0.67548973	FALSE	0	ADCY6	8182	0.14240269
792329	taxon:9606	2.91318733	6.60E-07	165832	1902	spermidine/spermine N1-acetyltransferase family member 2	gene	biological_process-&-1&-GO:0032919-&&-spermine acetylation-%%-GO:0046204-&&-nor-spermidine metabolic process-%%-GO:0032920-&&-putrescine acetylation-%%-GO:0009447-&&-putrescine catabolic process-%%-GO:0032918-&&-spermidine acetylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004145-&&-diamine N-acetyltransferase activity-%%-GO:0042802-&&-identical protein binding	G:9606:SAT2			KEGG-&-1&-hsa00330-&&-Arginine and proline metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04216-&&-Ferroptosis	SAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SAT2	0.34326663	0.4	8	5	FALSE	SAT2	SAT2	172.6666667	0	7	0	0.68113544	FALSE	1	SAT2	1806	0.19965278
792346	taxon:9606	2.94595872	2.90E-06	182190	1902	cholinergic receptor muscarinic 4	gene	biological_process-&-1&-GO:0040012-&&-regulation of locomotion-%%-GO:0007197-&&-adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007207-&&-phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0016907-&&-G-protein coupled acetylcholine receptor activity	G:9606:CHRM4	CHRM4	TRUE	KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CHRM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHRM4	0.33944807	0.2	8	5	FALSE	CHRM4	CHRM4	140	0	7	0	0.67567355	FALSE	1	CHRM4	4652	0.18825911
792399	taxon:9606	2.88293682	1.49E-04	182095	1902	hyaluronan and proteoglycan link protein 1	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0007417-&&-central nervous system development-%%-GO:0007155-&&-cell adhesion-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0005540-&&-hyaluronic acid binding-%%-GO:0005201-&&-extracellular matrix structural constituent	G:9606:HAPLN1				HAPLN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAPLN1	0.34686851	0.21428571	8	4	FALSE	HAPLN1	HAPLN1	145.25	0	8	0	0.6861772	FALSE	0	HAPLN1	124044	0.13326446
792403	taxon:9606	2.99968489	5.40E-07	182080	1902	crystallin gamma C	gene	biological_process-&-1&-GO:0007601-&&-visual perception|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005212-&&-structural constituent of eye lens-%%-GO:0005515-&&-protein binding	G:9606:CRYGC				CRYGC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRYGC	0.33336835	0.86666667	8	5	FALSE	CRYGC	CRYGC	96.66666667	0	7	0	0.66671918	FALSE	1	CRYGC	780	0.18554063
792432	taxon:9606	2.97053726	1.39E-05	182034	1902	cystatin E/M	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0008544-&&-epidermis development-%%-GO:0009653-&&-anatomical structure morphogenesis|cellular_component-&-1&-GO:0001533-&&-cornified envelope-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity	G:9606:CST6				CST6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CST6	0.33663944	0.03571429	8	5	FALSE	CST6	CST6	87.25	0	8	0	0.67157712	FALSE	0	CST6	9640	0.1384
792471	taxon:9606	2.95226091	6.58E-06	181970	1902	azurocidin 1	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0070528-&&-protein kinase C signaling-%%-GO:0001774-&&-microglial cell activation-%%-GO:0008347-&&-glial cell migration-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0006508-&&-proteolysis-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0051607-&&-defense response to virus-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0050766-&&-positive regulation of phagocytosis-%%-GO:0016485-&&-protein processing-%%-GO:0042117-&&-monocyte activation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0050725-&&-positive regulation of interleukin-1 beta biosynthetic process-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0070944-&&-neutrophil mediated killing of bacterium-%%-GO:0050754-&&-positive regulation of fractalkine biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0045123-&&-cellular extravasation-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0035584-&&-calcium-mediated signaling using intracellular calcium source|cellular_component-&-1&-GO:0042582-&&-azurophil granule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0019898-&&-extrinsic component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0015643-&&-toxic substance binding-%%-GO:0008201-&&-heparin binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0043395-&&-heparan sulfate proteoglycan binding	G:9606:AZU1				AZU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AZU1	0.33872345	0.07142857	8	5	FALSE	AZU1	AZU1	91.125	0	8	0	0.67462318	FALSE	0	AZU1	5408	0.13566617
792479	taxon:9606	2.8440208	5.93E-06	181949	1902	branched chain keto acid dehydrogenase E1, alpha polypeptide	gene	biological_process-&-1&-GO:0046487-&&-glyoxylate metabolic process-%%-GO:0009083-&&-branched-chain amino acid catabolic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005947-&&-mitochondrial alpha-ketoglutarate dehydrogenase complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003863-&&-3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003826-&&-alpha-ketoacid dehydrogenase activity-%%-GO:0016831-&&-carboxy-lyase activity	G:9606:BCKDHA			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism	BCKDHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCKDHA	0.35161487	0.17857143	8	4	FALSE	BCKDHA	BCKDHA	182.875	0	8	0	0.6926632	FALSE	0	BCKDHA	7402	0.1498358
792584	taxon:9606	2.86749646	7.03E-06	181767	1902	CD6 molecule	gene	biological_process-&-1&-GO:0007157-&&-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-%%-GO:0045087-&&-innate immune response-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:1900017-&&-positive regulation of cytokine production involved in inflammatory response-%%-GO:0002438-&&-acute inflammatory response to antigenic stimulus-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0002250-&&-adaptive immune response-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0001771-&&-immunological synapse formation-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0001772-&&-immunological synapse-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0042101-&&-T cell receptor complex|molecular_function-&-1&-GO:0070891-&&-lipoteichoic acid binding-%%-GO:0001530-&&-lipopolysaccharide binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding	G:9606:CD6			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	CD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD6	0.34873626	0.14285714	8	4	FALSE	CD6	CD6	151.625	0	8	0	0.68875059	FALSE	0	CD6	7106	0.14032033
792597	taxon:9606	2.7694974	4.45E-06	181737	1902	dual specificity phosphatase 4	gene	biological_process-&-1&-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0001706-&&-endoderm formation-%%-GO:0016311-&&-dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0000188-&&-inactivation of MAPK activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008330-&&-protein tyrosine/threonine phosphatase activity-%%-GO:1990439-&&-MAP kinase threonine phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0016791-&&-phosphatase activity	G:9606:DUSP4			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP4	0.36107635	0.32142857	8	5	FALSE	DUSP4	DUSP4	275.375	0	8	0	0.70508377	FALSE	0	DUSP4	9262	0.16956589
792603	taxon:9606	2.84197259	9.63E-06	181735	1902	dual specificity phosphatase 6	gene	biological_process-&-1&-GO:0014070-&&-response to organic cyclic compound-%%-GO:0060420-&&-regulation of heart growth-%%-GO:0040036-&&-regulation of fibroblast growth factor receptor signaling pathway-%%-GO:0042663-&&-regulation of endodermal cell fate specification-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0042493-&&-response to drug-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0051409-&&-response to nitrosative stress-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0070848-&&-response to growth factor|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:DUSP6			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05221-&&-Acute myeloid leukemia-%%-hsa04010-&&-MAPK signaling pathway	DUSP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP6	0.35186828	0.17857143	8	5	FALSE	DUSP6	DUSP6	199.375	0	8	0	0.69300457	FALSE	0	DUSP6	8940	0.16351684
792710	taxon:9606	2.99543091	8.25E-06	181522	1902	cochlin	gene	biological_process-&-1&-GO:0042742-&&-defense response to bacterium-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0008360-&&-regulation of cell shape|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0005515-&&-protein binding	G:9606:COCH				COCH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COCH	0.33384178	0	8	5	FALSE	COCH	COCH	92.5	0	8	0	0.66742818	FALSE	0	COCH	6408	0.13905775
792737	taxon:9606	2.86544824	3.42E-06	165081	1902	heat shock protein family B (small) member 6	gene	biological_process-&-1&-GO:0006937-&&-regulation of muscle contraction-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0061077-&&-chaperone-mediated protein folding-%%-GO:0010667-&&-negative regulation of cardiac muscle cell apoptotic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0051087-&&-chaperone binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0005212-&&-structural constituent of eye lens	G:9606:HSPB6				HSPB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPB6	0.34898554	0.25	8	4	FALSE	HSPB6	HSPB6	166.75	0	8	0	0.68909196	FALSE	0	HSPB6	4050	0.15445269
792856	taxon:9606	2.68221207	9.80E-07	164876	1902	DIS3 like 3'-5' exoribonuclease 2	gene	biological_process-&-1&-GO:0010587-&&-miRNA catabolic process-%%-GO:0006364-&&-rRNA processing-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0000291-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic-%%-GO:0034427-&&-nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'-%%-GO:0051301-&&-cell division-%%-GO:1990074-&&-polyuridylation-dependent mRNA catabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0019827-&&-stem cell population maintenance-%%-GO:0051306-&&-mitotic sister chromatid separation-%%-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0005737-&&-cytoplasm-%%-GO:0000178-&&-exosome (RNase complex)-%%-GO:0005844-&&-polysome|molecular_function-&-1&-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0004540-&&-ribonuclease activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0008266-&&-poly(U) RNA binding	G:9606:DIS3L2				DIS3L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DIS3L2	0.3728266	0.25	8	4	FALSE	DIS3L2	DIS3L2	370.375	0	8	0	0.71963132	FALSE	0	DIS3L2	4224	0.17456388
792903	taxon:9606	2.80289901	9.98E-06	164809	1902	DnaJ heat shock protein family (Hsp40) member C19	gene	biological_process-&-1&-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0006457-&&-protein folding-%%-GO:0007601-&&-visual perception-%%-GO:0048806-&&-genitalia development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0043234-&&-protein complex-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DNAJC19				DNAJC19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC19	0.35677347	0.07142857	8	4	FALSE	DNAJC19	DNAJC19	215.5	0	8	0	0.69951683	FALSE	0	DNAJC19	9814	0.15100141
792908	taxon:9606	3.47817867	8.18E-06	181173	1902	atypical chemokine receptor 1 (Duffy blood group)	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006952-&&-defense response-%%-GO:0032642-&&-regulation of chemokine production-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0055037-&&-recycling endosome|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0019957-&&-C-C chemokine binding-%%-GO:0004872-&&-receptor activity	G:9606:ACKR1			KEGG-&-1&-hsa05144-&&-Malaria	ACKR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACKR1	0.28750679	0.03571429	8	5	FALSE	ACKR1	ACKR1	13.625	0	8	0	0.58697022	FALSE	0	ACKR1	10468	0.18933824
792912	taxon:9606	3.14495037	4.12E-06	164780	1902	TAM41 mitochondrial translocator assembly and maintenance homolog	gene	biological_process-&-1&-GO:0016024-&&-CDP-diacylglycerol biosynthetic process-%%-GO:0032049-&&-cardiolipin biosynthetic process|cellular_component-&-1&-GO:0031314-&&-extrinsic component of mitochondrial inner membrane|molecular_function-&-1&-GO:0004605-&&-phosphatidate cytidylyltransferase activity	G:9606:TAMM41				TAMM41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TAMM41	0.31797004	0.26666667	8	5	FALSE	TAMM41	TAMM41	75.16666667	0	7	0	0.64250827	FALSE	1	TAMM41	3650	0.23240166
792933	taxon:9606	2.74350087	5.55E-06	181116	1902	acyl-CoA synthetase long-chain family member 1	gene	biological_process-&-1&-GO:0044539-&&-long-chain fatty acid import-%%-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0007584-&&-response to nutrient-%%-GO:0043651-&&-linoleic acid metabolic process-%%-GO:0008610-&&-lipid biosynthetic process-%%-GO:0034201-&&-response to oleic acid-%%-GO:0042493-&&-response to drug-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process-%%-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0036109-&&-alpha-linolenic acid metabolic process-%%-GO:0006641-&&-triglyceride metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004467-&&-long-chain fatty acid-CoA ligase activity-%%-GO:0102391-&&-decanoate--CoA ligase activity	G:9606:ACSL1			KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00061-&&-Fatty acid biosynthesis-%%-hsa04714-&&-Thermogenesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa04216-&&-Ferroptosis-%%-hsa00071-&&-Fatty acid degradation	ACSL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACSL1	0.36449779	0.03571429	8	4	FALSE	ACSL1	ACSL1	287.375	0	8	0	0.70941652	FALSE	0	ACSL1	14988	0.15905938
792988	taxon:9606	2.84764456	1.39E-05	164655	1902	RAB40A, member RAS oncogene family	gene	biological_process-&-1&-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0009306-&&-protein secretion-%%-GO:0006904-&&-vesicle docking involved in exocytosis|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding	G:9606:RAB40A				RAB40A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB40A	0.35116742	0.25	8	5	FALSE	RAB40A	RAB40A	190	0	8	0	0.69205924	FALSE	0	RAB40A	10536	0.15681818
793020	taxon:9606	2.90830314	1.70E-06	180880	1902	glutathione peroxidase 7	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004601-&&-peroxidase activity-%%-GO:0004096-&&-catalase activity	G:9606:GPX7			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa00590-&&-Arachidonic acid metabolism	GPX7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPX7	0.34384311	0.14285714	8	5	FALSE	GPX7	GPX7	123.875	0	8	0	0.68194948	FALSE	0	GPX7	2794	0.15418227
793058	taxon:9606	2.87805262	1.04E-05	180817	1902	glutathione S-transferase theta 1	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity-%%-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0005515-&&-protein binding	G:9606:GSTT1	GSTT1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTT1	0.34745716	0.06666667	8	4	FALSE	GSTT1	GSTT1	188	0	7	0	0.68699123	FALSE	1	GSTT1	9082	0.17739899
793091	taxon:9606	2.94123208	1.12E-06	164364	1902	piwi like RNA-mediated gene silencing 4	gene	biological_process-&-1&-GO:0034587-&&-piRNA metabolic process-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0007283-&&-spermatogenesis-%%-GO:0006417-&&-regulation of translation-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0030154-&&-cell differentiation-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010529-&&-negative regulation of transposition|cellular_component-&-1&-GO:0043186-&&-P granule-%%-GO:0071547-&&-piP-body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0034584-&&-piRNA binding-%%-GO:0004521-&&-endoribonuclease activity	G:9606:PIWIL4				PIWIL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIWIL4	0.33999357	0.17857143	8	4	FALSE	PIWIL4	PIWIL4	108.875	0	8	0	0.67646132	FALSE	0	PIWIL4	2260	0.16433434
793109	taxon:9606	3.08618245	6.80E-07	180716	1902	nuclear receptor subfamily 6 group A member 1	gene	biological_process-&-1&-GO:0006367-&&-transcription initiation from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007276-&&-gamete generation-%%-GO:0030518-&&-intracellular steroid hormone receptor signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005667-&&-transcription factor complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0004879-&&-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0003707-&&-steroid hormone receptor activity	G:9606:NR6A1				NR6A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NR6A1	0.32402491	0.06666667	8	5	FALSE	NR6A1	NR6A1	83.33333333	0	7	0	0.65230293	FALSE	1	NR6A1	912	0.21811785
793120	taxon:9606	3.10146526	2.22E-06	180692	1902	gamma-glutamyltransferase 1	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0006749-&&-glutathione metabolic process-%%-GO:0019344-&&-cysteine biosynthetic process-%%-GO:0006536-&&-glutamate metabolic process-%%-GO:0006751-&&-glutathione catabolic process-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0006750-&&-glutathione biosynthetic process-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0019370-&&-leukotriene biosynthetic process-%%-GO:0031638-&&-zymogen activation-%%-GO:0006691-&&-leukotriene metabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0002682-&&-regulation of immune system process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031362-&&-anchored component of external side of plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0003840-&&-gamma-glutamyltransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0036374-&&-glutathione hydrolase activity	G:9606:GGT1	GGT1	TRUE	KEGG-&-1&-hsa00430-&&-Taurine and hypotaurine metabolism-%%-hsa00480-&&-Glutathione metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	GGT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GGT1	0.32242824	0.33333333	8	5	FALSE	GGT1	GGT1	68	0	7	0	0.64975579	FALSE	1	GGT1	1762	0.18333333
793128	taxon:9606	3.20560895	1.19E-05	180679	1902	gastric inhibitory polypeptide	gene	biological_process-&-1&-GO:0033993-&&-response to lipid-%%-GO:0035640-&&-exploration behavior-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0010447-&&-response to acidic pH-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0007165-&&-signal transduction-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0007613-&&-memory-%%-GO:0010269-&&-response to selenium ion-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0007565-&&-female pregnancy-%%-GO:0042594-&&-response to starvation-%%-GO:0070094-&&-positive regulation of glucagon secretion-%%-GO:0010828-&&-positive regulation of glucose transport-%%-GO:0009749-&&-response to glucose-%%-GO:0043200-&&-response to amino acid-%%-GO:0048678-&&-response to axon injury-%%-GO:0055123-&&-digestive system development-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0042493-&&-response to drug-%%-GO:0019233-&&-sensory perception of pain|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding	G:9606:GIP	GIP	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04911-&&-Insulin secretion-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GIP	0.31195321	0.17857143	8	5	FALSE	GIP	GIP	72.125	0	8	0	0.63239851	FALSE	0	GIP	12108	0.25174825
793197	taxon:9606	3.0048842	7.35E-06	180546	1902	hemopexin	gene	biological_process-&-1&-GO:0042168-&&-heme metabolic process-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0002925-&&-positive regulation of humoral immune response mediated by circulating immunoglobulin-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0020027-&&-hemoglobin metabolic process-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0015886-&&-heme transport-%%-GO:0016032-&&-viral process-%%-GO:0002639-&&-positive regulation of immunoglobulin production-%%-GO:0060335-&&-positive regulation of interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0071682-&&-endocytic vesicle lumen|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0015232-&&-heme transporter activity-%%-GO:0005515-&&-protein binding	G:9606:HPX				HPX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPX	0.33279153	0.07142857	8	5	FALSE	HPX	HPX	73.375	0	8	0	0.66585263	FALSE	0	HPX	7330	0.14123062
793255	taxon:9606	2.92279817	2.54E-05	180438	1902	C-C motif chemokine receptor 10	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0016493-&&-C-C chemokine receptor activity	G:9606:CCR10			KEGG-&-1&-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCR10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCR10	0.34213789	0.14285714	8	5	FALSE	CCR10	CCR10	134.875	0	8	0	0.67953364	FALSE	0	CCR10	20106	0.17183504
793336	taxon:9606	2.83015598	8.39E-06	180288	1902	major histocompatibility complex, class II, DR beta 3	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0042613-&&-MHC class II protein complex-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0016020-&&-membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0032395-&&-MHC class II receptor activity-%%-GO:0042605-&&-peptide antigen binding	G:9606:HLA-DRB3			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05310-&&-Asthma-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04145-&&-Phagosome-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05323-&&-Rheumatoid arthritis	HLA-DRB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-DRB3	0.35333742	0.14285714	8	4	FALSE	HLA-DRB3	HLA-DRB3	205.125	0	8	0	0.694974	FALSE	0	HLA-DRB3	7790	0.16383106
787025	taxon:9606	3.03812825	5.12E-06	180215	1902	integrin subunit beta 8	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0001573-&&-ganglioside metabolic process-%%-GO:0060674-&&-placenta blood vessel development-%%-GO:0007160-&&-cell-matrix adhesion-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0051216-&&-cartilage development-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0007229-&&-integrin-mediated signaling pathway|cellular_component-&-1&-GO:0034686-&&-integrin alphav-beta8 complex-%%-GO:0009986-&&-cell surface-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:1990430-&&-extracellular matrix protein binding-%%-GO:0004872-&&-receptor activity	G:9606:ITGB8			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGB8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGB8	0.32915003	0.0952381	7	5	FALSE	ITGB8	ITGB8	67.85714286	0	7	0	0.66031196	FALSE	0	ITGB8	3570	0.15503621
787057	taxon:9606	2.96644084	6.40E-06	180154	1902	interferon induced protein 35	gene	biological_process-&-1&-GO:0060337-&&-type I interferon signaling pathway|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:IFI35				IFI35	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFI35	0.33710431	0.14285714	7	5	FALSE	IFI35	IFI35	101.4285714	0	7	0	0.67225986	FALSE	0	IFI35	4626	0.15562404
787066	taxon:9606	3.10020482	4.02E-06	180131	1902	interferon gamma	gene	biological_process-&-1&-GO:0051712-&&-positive regulation of killing of cells of other organism-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0030857-&&-negative regulation of epithelial cell differentiation-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0033141-&&-positive regulation of peptidyl-serine phosphorylation of STAT protein-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002026-&&-regulation of the force of heart contraction-%%-GO:1903543-&&-positive regulation of exosomal secretion-%%-GO:0006959-&&-humoral immune response-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0060550-&&-positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity-%%-GO:0060552-&&-positive regulation of fructose 1,6-bisphosphate metabolic process-%%-GO:0071351-&&-cellular response to interleukin-18-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0032834-&&-positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response-%%-GO:0050718-&&-positive regulation of interleukin-1 beta secretion-%%-GO:0032747-&&-positive regulation of interleukin-23 production-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0045084-&&-positive regulation of interleukin-12 biosynthetic process-%%-GO:0001781-&&-neutrophil apoptotic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0060559-&&-positive regulation of calcidiol 1-monooxygenase activity-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0009615-&&-response to virus-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0002250-&&-adaptive immune response-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0072125-&&-negative regulation of glomerular mesangial cell proliferation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0031642-&&-negative regulation of myelination-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0060334-&&-regulation of interferon-gamma-mediated signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0002302-&&-CD8-positive, alpha-beta T cell differentiation involved in immune response-%%-GO:0060557-&&-positive regulation of vitamin D biosynthetic process-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0032224-&&-positive regulation of synaptic transmission, cholinergic-%%-GO:0098908-&&-regulation of neuronal action potential-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:0042511-&&-positive regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0051607-&&-defense response to virus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0060251-&&-regulation of glial cell proliferation-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0050954-&&-sensory perception of mechanical stimulus-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:2000309-&&-positive regulation of tumor necrosis factor (ligand) superfamily member 11 production-%%-GO:2000345-&&-regulation of hepatocyte proliferation-%%-GO:0030968-&&-endoplasmic reticulum unfolded protein response-%%-GO:0032735-&&-positive regulation of interleukin-12 production|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0043204-&&-perikaryon-%%-GO:0005615-&&-extracellular space-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0005133-&&-interferon-gamma receptor binding	G:9606:IFNG	IFNG	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa03050-&&-Proteasome-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05164-&&-Influenza A-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04350-&&-TGF-beta signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa04660-&&-T cell receptor signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05330-&&-Allograft rejection-%%-hsa05132-&&-Salmonella infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05160-&&-Hepatitis C-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04380-&&-Osteoclast differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04217-&&-Necroptosis-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	IFNG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNG	0.32255933	0.1	7	5	FALSE	IFNG	IFNG	58.4	0	6	0	0.64996586	FALSE	1	IFNG	1920	0.2125
787076	taxon:9606	3.05073263	7.66E-06	180112	1902	insulin like growth factor binding protein 4	gene	biological_process-&-1&-GO:0010906-&&-regulation of glucose metabolic process-%%-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0001501-&&-skeletal system development-%%-GO:0006259-&&-DNA metabolic process-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008283-&&-cell proliferation-%%-GO:0044342-&&-type B pancreatic cell proliferation-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006954-&&-inflammatory response-%%-GO:0007165-&&-signal transduction-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0031995-&&-insulin-like growth factor II binding	G:9606:IGFBP4	IGFBP4	TRUE		IGFBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP4	0.32779012	0.14285714	7	5	FALSE	IGFBP4	IGFBP4	69.85714286	0	7	0	0.65821123	FALSE	0	IGFBP4	6552	0.17220651
787080	taxon:9606	2.80699543	2.18E-06	180108	1902	cysteine rich angiogenic inducer 61	gene	biological_process-&-1&-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0033690-&&-positive regulation of osteoblast proliferation-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0072593-&&-reactive oxygen species metabolic process-%%-GO:0044319-&&-wound healing, spreading of cells-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0060591-&&-chondroblast differentiation-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0006935-&&-chemotaxis-%%-GO:0010518-&&-positive regulation of phospholipase activity-%%-GO:0003281-&&-ventricular septum development-%%-GO:0008283-&&-cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0003278-&&-apoptotic process involved in heart morphogenesis-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010811-&&-positive regulation of cell-substrate adhesion-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process-%%-GO:0002041-&&-intussusceptive angiogenesis-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0003181-&&-atrioventricular valve morphogenesis-%%-GO:0060716-&&-labyrinthine layer blood vessel development-%%-GO:0060710-&&-chorio-allantoic fusion-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0061036-&&-positive regulation of cartilage development|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0050840-&&-extracellular matrix binding-%%-GO:0005178-&&-integrin binding-%%-GO:0008201-&&-heparin binding-%%-GO:0005520-&&-insulin-like growth factor binding	G:9606:CYR61				CYR61	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYR61	0.35625281	0.0952381	7	4	FALSE	CYR61	CYR61	254	0	7	0	0.69883409	FALSE	0	CYR61	5198	0.17782008
787084	taxon:9606	2.73987711	8.83E-06	180097	1902	immunoglobulin heavy constant gamma 3 (G3m marker)	gene	biological_process-&-1&-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0006956-&&-complement activation-%%-GO:0045087-&&-innate immune response-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006508-&&-proteolysis-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0050871-&&-positive regulation of B cell activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042571-&&-immunoglobulin complex, circulating-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0003823-&&-antigen binding-%%-GO:0034987-&&-immunoglobulin receptor binding	G:9606:IGHG3				IGHG3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGHG3	0.36497987	0.0952381	7	4	FALSE	IGHG3	IGHG3	306.1428571	0	7	0	0.71002048	FALSE	0	IGHG3	9376	0.17371883
787092	taxon:9606	2.99669135	2.01E-06	163686	1902	serum response factor binding protein 1	gene	biological_process-&-1&-GO:0030490-&&-maturation of SSU-rRNA-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0030686-&&-90S preribosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding	G:9606:SRFBP1				SRFBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRFBP1	0.33370137	0.04761905	7	5	FALSE	SRFBP1	SRFBP1	95.71428571	0	7	0	0.66721811	FALSE	0	SRFBP1	2802	0.1637931
787105	taxon:9606	3.27965968	5.26E-06	180051	1902	interleukin 4	gene	biological_process-&-1&-GO:0002674-&&-negative regulation of acute inflammatory response-%%-GO:0045064-&&-T-helper 2 cell differentiation-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0048304-&&-positive regulation of isotype switching to IgG isotypes-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:2000424-&&-positive regulation of eosinophil chemotaxis-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045189-&&-connective tissue growth factor biosynthetic process-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0071677-&&-positive regulation of mononuclear cell migration-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0030183-&&-B cell differentiation-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:2000320-&&-negative regulation of T-helper 17 cell differentiation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0045471-&&-response to ethanol-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0007565-&&-female pregnancy-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0050776-&&-regulation of immune response-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:1903428-&&-positive regulation of reactive oxygen species biosynthetic process-%%-GO:0071288-&&-cellular response to mercury ion-%%-GO:0045671-&&-negative regulation of osteoclast differentiation-%%-GO:0007584-&&-response to nutrient-%%-GO:0006968-&&-cellular defense response-%%-GO:0006955-&&-immune response-%%-GO:0097192-&&-extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0042493-&&-response to drug-%%-GO:0010155-&&-regulation of proton transport-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0097028-&&-dendritic cell differentiation-%%-GO:0045080-&&-positive regulation of chemokine biosynthetic process-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0032733-&&-positive regulation of interleukin-10 production-%%-GO:0070351-&&-negative regulation of white fat cell proliferation-%%-GO:0001774-&&-microglial cell activation-%%-GO:0006935-&&-chemotaxis-%%-GO:0043031-&&-negative regulation of macrophage activation-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0002296-&&-T-helper 1 cell lineage commitment-%%-GO:0032736-&&-positive regulation of interleukin-13 production-%%-GO:0031296-&&-B cell costimulation-%%-GO:0045191-&&-regulation of isotype switching-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0002677-&&-negative regulation of chronic inflammatory response-%%-GO:0042092-&&-type 2 immune response-%%-GO:0042325-&&-regulation of phosphorylation-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0048295-&&-positive regulation of isotype switching to IgE isotypes-%%-GO:0034097-&&-response to cytokine-%%-GO:1903660-&&-negative regulation of complement-dependent cytotoxicity-%%-GO:0035745-&&-T-helper 2 cell cytokine production|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005136-&&-interleukin-4 receptor binding-%%-GO:0008083-&&-growth factor activity	G:9606:IL4	IL4	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05140-&&-Leishmaniasis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04660-&&-T cell receptor signaling pathway	IL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL4	0.30490968	0.14285714	7	5	FALSE	IL4	IL4	25.42857143	0	7	0	0.62005672	FALSE	0	IL4	3306	0.15633423
787108	taxon:9606	3.14951946	7.00E-06	180047	1902	interleukin 6	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2000553-&&-positive regulation of T-helper 2 cell cytokine production-%%-GO:0001781-&&-neutrophil apoptotic process-%%-GO:0031000-&&-response to caffeine-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0070102-&&-interleukin-6-mediated signaling pathway-%%-GO:0072540-&&-T-helper 17 cell lineage commitment-%%-GO:1990646-&&-cellular response to prolactin-%%-GO:0032722-&&-positive regulation of chemokine production-%%-GO:0032966-&&-negative regulation of collagen biosynthetic process-%%-GO:0032868-&&-response to insulin-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:2000660-&&-negative regulation of interleukin-1-mediated signaling pathway-%%-GO:0045079-&&-negative regulation of chemokine biosynthetic process-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0045429-&&-positive regulation of nitric oxide biosynthetic process-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0010996-&&-response to auditory stimulus-%%-GO:0001878-&&-response to yeast-%%-GO:0051607-&&-defense response to virus-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0051971-&&-positive regulation of transmission of nerve impulse-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0043200-&&-response to amino acid-%%-GO:0046677-&&-response to antibiotic-%%-GO:0046849-&&-bone remodeling-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0009408-&&-response to heat-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0006953-&&-acute-phase response-%%-GO:0030168-&&-platelet activation-%%-GO:0002675-&&-positive regulation of acute inflammatory response-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0002384-&&-hepatic immune response-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0032494-&&-response to peptidoglycan-%%-GO:0051592-&&-response to calcium ion-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0045454-&&-cell redox homeostasis-%%-GO:0045669-&&-positive regulation of osteoblast differentiation-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006959-&&-humoral immune response-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0060445-&&-branching involved in salivary gland morphogenesis-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0031669-&&-cellular response to nutrient levels-%%-GO:0050871-&&-positive regulation of B cell activation-%%-GO:0006954-&&-inflammatory response-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0048635-&&-negative regulation of muscle organ development-%%-GO:0070091-&&-glucagon secretion-%%-GO:0009409-&&-response to cold-%%-GO:0042832-&&-defense response to protozoan-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0071864-&&-positive regulation of cell proliferation in bone marrow-%%-GO:0046716-&&-muscle cell cellular homeostasis-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0045779-&&-negative regulation of bone resorption-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0032755-&&-positive regulation of interleukin-6 production-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0016049-&&-cell growth-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0046888-&&-negative regulation of hormone secretion-%%-GO:2000676-&&-positive regulation of type B pancreatic cell apoptotic process-%%-GO:0042493-&&-response to drug-%%-GO:0031294-&&-lymphocyte costimulation-%%-GO:0033160-&&-positive regulation of protein import into nucleus, translocation-%%-GO:1901215-&&-negative regulation of neuron death-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0010574-&&-regulation of vascular endothelial growth factor production-%%-GO:0045837-&&-negative regulation of membrane potential-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0031175-&&-neuron projection development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0045188-&&-regulation of circadian sleep/wake cycle, non-REM sleep-%%-GO:0007568-&&-aging-%%-GO:0045721-&&-negative regulation of gluconeogenesis-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:2000366-&&-positive regulation of STAT protein import into nucleus-%%-GO:0051024-&&-positive regulation of immunoglobulin secretion-%%-GO:0050710-&&-negative regulation of cytokine secretion|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005896-&&-interleukin-6 receptor complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005138-&&-interleukin-6 receptor binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0008083-&&-growth factor activity	G:9606:IL6	IL6	TRUE	KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05152-&&-Tuberculosis-%%-hsa04931-&&-Insulin resistance-%%-hsa05161-&&-Hepatitis B-%%-hsa05134-&&-Legionellosis-%%-hsa05164-&&-Influenza A-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05146-&&-Amoebiasis-%%-hsa05020-&&-Prion diseases-%%-hsa05200-&&-Pathways in cancer-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04066-&&-HIF-1 signaling pathway-%%-hsa01523-&&-Antifolate resistance-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05132-&&-Salmonella infection-%%-hsa04668-&&-TNF signaling pathway-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa04218-&&-Cellular senescence-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05133-&&-Pertussis-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	IL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL6	0.31750875	0.14285714	7	5	FALSE	IL6	IL6	31.85714286	0	7	0	0.64174676	FALSE	0	IL6	7946	0.1547619
787121	taxon:9606	3.1723649	5.26E-06	180025	1902	interleukin 13 receptor subunit alpha 1	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005898-&&-interleukin-13 receptor complex|molecular_function-&-1&-GO:0004896-&&-cytokine receptor activity-%%-GO:0005515-&&-protein binding	G:9606:IL13RA1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL13RA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL13RA1	0.31522225	0.19047619	7	5	FALSE	IL13RA1	IL13RA1	35.57142857	0	7	0	0.63793918	FALSE	0	IL13RA1	5998	0.16194865
787128	taxon:9606	3.04380022	5.80E-06	180019	1902	interleukin 17A	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:1900017-&&-positive regulation of cytokine production involved in inflammatory response-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:0072537-&&-fibroblast activation-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006954-&&-inflammatory response-%%-GO:0050832-&&-defense response to fungus-%%-GO:0006955-&&-immune response-%%-GO:0008219-&&-cell death-%%-GO:0032747-&&-positive regulation of interleukin-23 production|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:IL17A	IL17A	TRUE	KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	IL17A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL17A	0.32853667	0.1	7	5	FALSE	IL17A	IL17A	101.6	0	6	0	0.65936663	FALSE	1	IL17A	5424	0.20910973
787148	taxon:9606	2.84149992	2.47E-06	163602	1902	PEAK1 related kinase activating pseudokinase 1	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity	G:9606:PRAG1				PRAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRAG1	0.35192681	0.19047619	7	4	FALSE	PRAG1	PRAG1	210.7142857	0	7	0	0.69308335	FALSE	0	PRAG1	3990	0.17538425
787275	taxon:9606	2.92453127	1.29E-05	179766	1902	potassium voltage-gated channel subfamily A member 6	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0034705-&&-potassium channel complex-%%-GO:0030424-&&-axon-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0043679-&&-axon terminus|molecular_function-&-1&-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0005249-&&-voltage-gated potassium channel activity	G:9606:KCNA6				KCNA6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNA6	0.34193514	0.04761905	7	5	FALSE	KCNA6	KCNA6	117.7142857	0	7	0	0.67924479	FALSE	0	KCNA6	8924	0.15214564
787280	taxon:9606	3.12478336	2.59E-06	179748	1902	potassium voltage-gated channel subfamily J member 3	gene	biological_process-&-1&-GO:0098914-&&-membrane repolarization during atrial cardiac muscle cell action potential-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:0099625-&&-ventricular cardiac muscle cell membrane repolarization|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0030315-&&-T-tubule|molecular_function-&-1&-GO:0086089-&&-voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization-%%-GO:0015467-&&-G-protein activated inward rectifier potassium channel activity-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0005242-&&-inward rectifier potassium channel activity-%%-GO:0005515-&&-protein binding	G:9606:KCNJ3			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04725-&&-Cholinergic synapse-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	KCNJ3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNJ3	0.32002219	0.47619048	7	5	FALSE	KCNJ3	KCNJ3	53.71428571	0	7	0	0.64586944	FALSE	0	KCNJ3	4676	0.15891801
787286	taxon:9606	3.21269891	7.40E-07	179743	1902	potassium voltage-gated channel subfamily J member 9	gene	biological_process-&-1&-GO:0010107-&&-potassium ion import-%%-GO:0034765-&&-regulation of ion transmembrane transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015467-&&-G-protein activated inward rectifier potassium channel activity-%%-GO:0005242-&&-inward rectifier potassium channel activity-%%-GO:0005515-&&-protein binding	G:9606:KCNJ9			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05032-&&-Morphine addiction-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	KCNJ9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNJ9	0.31126477	0.6	7	5	FALSE	KCNJ9	KCNJ9	60.6	0	6	0	0.63121685	FALSE	1	KCNJ9	826	0.21798561
787366	taxon:9606	2.79376083	1.65E-06	179559	1902	methylmalonyl-CoA mutase	gene	biological_process-&-1&-GO:0009791-&&-post-embryonic development-%%-GO:0050667-&&-homocysteine metabolic process-%%-GO:0009235-&&-cobalamin metabolic process-%%-GO:0019626-&&-short-chain fatty acid catabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0004494-&&-methylmalonyl-CoA mutase activity-%%-GO:0072341-&&-modified amino acid binding-%%-GO:0031419-&&-cobalamin binding-%%-GO:0046872-&&-metal ion binding	G:9606:MUT			KEGG-&-1&-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00280-&&-Valine, leucine and isoleucine degradation-%%-hsa00640-&&-Propanoate metabolism-%%-hsa00630-&&-Glyoxylate and dicarboxylate metabolism	MUT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MUT	0.35794045	0.1	7	5	FALSE	MUT	MUT	350.6	0	6	0	0.70103986	FALSE	1	MUT	4390	0.2188868
787471	taxon:9606	2.86607846	1.23E-06	179375	1902	microsomal glutathione S-transferase 1	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0033327-&&-Leydig cell differentiation-%%-GO:0071449-&&-cellular response to lipid hydroperoxide-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0070207-&&-protein homotrimerization-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0042493-&&-response to drug-%%-GO:0010243-&&-response to organonitrogen compound-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0098869-&&-cellular oxidant detoxification|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005886-&&-plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0005778-&&-peroxisomal membrane-%%-GO:0035577-&&-azurophil granule membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0043295-&&-glutathione binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004364-&&-glutathione transferase activity	G:9606:MGST1			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	MGST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGST1	0.3489088	0.1	7	4	FALSE	MGST1	MGST1	259	0	6	0	0.68898692	FALSE	1	MGST1	4020	0.22646801
787563	taxon:9606	2.82747755	5.33E-06	162786	1902	SUMO1/sentrin specific peptidase 5	gene	biological_process-&-1&-GO:0016926-&&-protein desumoylation-%%-GO:0016925-&&-protein sumoylation-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0070139-&&-SUMO-specific endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0016929-&&-SUMO-specific protease activity	G:9606:SENP5				SENP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SENP5	0.35367213	0.14285714	7	4	FALSE	SENP5	SENP5	230.2857143	0	7	0	0.69542041	FALSE	0	SENP5	6206	0.17873806
787605	taxon:9606	2.9237435	2.30E-06	162725	1902	trypsin domain containing 1	gene	biological_process-&-1&-GO:0016485-&&-protein processing-%%-GO:0031998-&&-regulation of fatty acid beta-oxidation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005777-&&-peroxisome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0002020-&&-protease binding-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:TYSND1				TYSND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TYSND1	0.34202727	0.4	7	5	FALSE	TYSND1	TYSND1	181.6	0	6	0	0.67937608	FALSE	1	TYSND1	2968	0.20755149
787655	taxon:9606	2.6782732	7.39E-06	179007	1902	receptor tyrosine kinase like orphan receptor 1	gene	biological_process-&-1&-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0014002-&&-astrocyte development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0009986-&&-cell surface-%%-GO:0001725-&&-stress fiber-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:1904929-&&-coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway-%%-GO:0005515-&&-protein binding-%%-GO:0017147-&&-Wnt-protein binding	G:9606:ROR1			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	ROR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROR1	0.3733749	0.14285714	7	4	FALSE	ROR1	ROR1	374.8571429	0	7	0	0.7202878	FALSE	0	ROR1	10356	0.17630038
787707	taxon:9606	2.93445722	2.80E-06	178910	1902	proteolipid protein 1	gene	biological_process-&-1&-GO:0048469-&&-cell maturation-%%-GO:0014002-&&-astrocyte development-%%-GO:0042759-&&-long-chain fatty acid biosynthetic process-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0006954-&&-inflammatory response-%%-GO:0021762-&&-substantia nigra development-%%-GO:0061564-&&-axon development-%%-GO:0007229-&&-integrin-mediated signaling pathway-%%-GO:0008366-&&-axon ensheathment-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0022010-&&-central nervous system myelination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0019911-&&-structural constituent of myelin sheath-%%-GO:0005515-&&-protein binding	G:9606:PLP1				PLP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLP1	0.34077852	0.19047619	7	5	FALSE	PLP1	PLP1	108.8571429	0	7	0	0.67759046	FALSE	0	PLP1	3310	0.16397328
787718	taxon:9606	3.02741453	1.11E-06	178891	1902	peripheral myelin protein 2	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0006810-&&-transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0005504-&&-fatty acid binding	G:9606:PMP2				PMP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMP2	0.33031486	0.61904762	7	4	FALSE	PMP2	PMP2	99.28571429	0	7	0	0.66209758	FALSE	0	PMP2	1022	0.22843976
787788	taxon:9606	2.96738617	2.21E-06	146020	1902	MT-RNR2-like 1	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region	G:9606:MTRNR2L1				MTRNR2L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTRNR2L1	0.33699692	0	7	5	FALSE	MTRNR2L1	MTRNR2L1	99.28571429	0	7	0	0.67210231	FALSE	0	MTRNR2L1	2882	0.16829746
787830	taxon:9606	2.87033244	2.37E-06	178743	1902	protein kinase, cGMP-dependent, type II	gene	biological_process-&-1&-GO:0036289-&&-peptidyl-serine autophosphorylation-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004692-&&-cGMP-dependent protein kinase activity-%%-GO:0030553-&&-cGMP binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0004672-&&-protein kinase activity	G:9606:PRKG2			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04714-&&-Thermogenesis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04611-&&-Platelet activation-%%-hsa04740-&&-Olfactory transduction-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	PRKG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRKG2	0.3483917	0.04761905	7	5	FALSE	PRKG2	PRKG2	177.8571429	0	7	0	0.68827793	FALSE	0	PRKG2	3750	0.16601955
787920	taxon:9606	2.8722231	1.91E-05	178611	1902	parathyroid hormone like hormone	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0008544-&&-epidermis development-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0007565-&&-female pregnancy-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0002076-&&-osteoblast development-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0046058-&&-cAMP metabolic process-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0001501-&&-skeletal system development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0051428-&&-peptide hormone receptor binding	G:9606:PTHLH			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	PTHLH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTHLH	0.34816237	0.0952381	7	4	FALSE	PTHLH	PTHLH	178	0	7	0	0.68796282	FALSE	0	PTHLH	19402	0.16847384
787938	taxon:9606	2.79896014	3.73E-06	178542	1902	purinergic receptor P2Y2	gene	biological_process-&-1&-GO:0006873-&&-cellular ion homeostasis-%%-GO:0035589-&&-G-protein coupled purinergic nucleotide receptor signaling pathway-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0070257-&&-positive regulation of mucus secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0045028-&&-G-protein coupled purinergic nucleotide receptor activity-%%-GO:0004872-&&-receptor activity	G:9606:P2RY2			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	P2RY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P2RY2	0.35727554	0.28571429	7	4	FALSE	P2RY2	P2RY2	233	0	7	0	0.70017331	FALSE	0	P2RY2	8126	0.16306523
788008	taxon:9606	2.87978573	2.13E-06	178411	1902	peroxisomal biogenesis factor 1	gene	biological_process-&-1&-GO:0006625-&&-protein targeting to peroxisome-%%-GO:0016558-&&-protein import into peroxisome matrix-%%-GO:0060152-&&-microtubule-based peroxisome localization-%%-GO:0007031-&&-peroxisome organization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005777-&&-peroxisome-%%-GO:0005778-&&-peroxisomal membrane|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0042623-&&-ATPase activity, coupled-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:PEX1			KEGG-&-1&-hsa04146-&&-Peroxisome	PEX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEX1	0.34724806	0.0952381	7	5	FALSE	PEX1	PEX1	163.8571429	0	7	0	0.68670238	FALSE	0	PEX1	4298	0.16610958
788037	taxon:9606	2.85804317	4.80E-07	178327	1902	ROS proto-oncogene 1, receptor tyrosine kinase	gene	biological_process-&-1&-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0002066-&&-columnar/cuboidal epithelial cell development-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0016049-&&-cell growth-%%-GO:0010966-&&-regulation of phosphate transport-%%-GO:0030154-&&-cell differentiation-%%-GO:0032006-&&-regulation of TOR signaling-%%-GO:0007283-&&-spermatogenesis-%%-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0019903-&&-protein phosphatase binding	G:9606:ROS1				ROS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ROS1	0.34988975	0.38095238	7	4	FALSE	ROS1	ROS1	215.4285714	0	7	0	0.69032614	FALSE	0	ROS1	1188	0.19750983
788078	taxon:9606	2.70915393	1.36E-06	178272	1902	ribosomal protein L41	gene	biological_process-&-1&-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006412-&&-translation-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0022625-&&-cytosolic large ribosomal subunit-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPL41			KEGG-&-1&-hsa03010-&&-Ribosome	RPL41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPL41	0.36911893	0.28571429	7	5	FALSE	RPL41	RPL41	345.5714286	0	7	0	0.71514101	FALSE	0	RPL41	4614	0.17687075
788116	taxon:9606	2.76540098	5.16E-06	178215	1902	protein tyrosine phosphatase, non-receptor type 7	gene	biological_process-&-1&-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0009898-&&-cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:PTPN7			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	PTPN7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPN7	0.36161121	0.14285714	7	5	FALSE	PTPN7	PTPN7	302.5714286	0	7	0	0.7057665	FALSE	0	PTPN7	10120	0.18607517
788186	taxon:9606	2.79832992	8.06E-06	178114	1902	receptor associated protein of the synapse	gene	biological_process-&-1&-GO:0043525-&&-positive regulation of neuron apoptotic process-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:1901626-&&-regulation of postsynaptic membrane organization-%%-GO:0007271-&&-synaptic transmission, cholinergic-%%-GO:1900075-&&-positive regulation of neuromuscular synaptic transmission-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030054-&&-cell junction-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005813-&&-centrosome-%%-GO:0099634-&&-postsynaptic specialization membrane-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0033130-&&-acetylcholine receptor binding-%%-GO:0043495-&&-protein anchor-%%-GO:0035255-&&-ionotropic glutamate receptor binding	G:9606:RAPSN				RAPSN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAPSN	0.357356	0.28571429	7	4	FALSE	RAPSN	RAPSN	242	0	7	0	0.70027835	FALSE	0	RAPSN	7754	0.17044196
788251	taxon:9606	2.84985032	4.89E-06	161617	1902	outer dense fiber of sperm tails 3 like 2	gene	cellular_component-&-1&-GO:0005881-&&-cytoplasmic microtubule	G:9606:ODF3L2				ODF3L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ODF3L2	0.35089562	0	7	5	FALSE	ODF3L2	ODF3L2	182.7142857	0	7	0	0.69169161	FALSE	0	ODF3L2	5612	0.15491414
788353	taxon:9606	3.47061604	1.38E-05	177817	1902	C-X-C motif chemokine ligand 5	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006954-&&-inflammatory response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006935-&&-chemotaxis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0045236-&&-CXCR chemokine receptor binding	G:9606:CXCL5			KEGG-&-1&-hsa04668-&&-TNF signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CXCL5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL5	0.28813328	0.04761905	7	5	FALSE	CXCL5	CXCL5	52.14285714	0	7	0	0.58823066	FALSE	0	CXCL5	14622	0.33834586
788397	taxon:9606	2.89317788	4.26E-06	177743	1902	heat shock protein family A (Hsp70) member 13	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:HSPA13				HSPA13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA13	0.34564069	0.19047619	7	5	FALSE	HSPA13	HSPA13	168.5714286	0	7	0	0.68447035	FALSE	0	HSPA13	8950	0.17274725
788417	taxon:9606	2.9153931	5.20E-05	177711	1902	semaphorin 3F	gene	biological_process-&-1&-GO:0021612-&&-facial nerve structural organization-%%-GO:0021675-&&-nerve development-%%-GO:1902285-&&-semaphorin-plexin signaling pathway involved in neuron projection guidance-%%-GO:0007411-&&-axon guidance-%%-GO:0048846-&&-axon extension involved in axon guidance-%%-GO:0097491-&&-sympathetic neuron projection guidance-%%-GO:1902287-&&-semaphorin-plexin signaling pathway involved in axon guidance-%%-GO:0021785-&&-branchiomotor neuron axon guidance-%%-GO:0021637-&&-trigeminal nerve structural organization-%%-GO:0048843-&&-negative regulation of axon extension involved in axon guidance-%%-GO:0050919-&&-negative chemotaxis-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:1901166-&&-neural crest cell migration involved in autonomic nervous system development-%%-GO:0036486-&&-ventral trunk neural crest cell migration-%%-GO:0097490-&&-sympathetic neuron projection extension|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0045499-&&-chemorepellent activity	G:9606:SEMA3F			KEGG-&-1&-hsa04360-&&-Axon guidance	SEMA3F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEMA3F	0.34300692	0.19047619	7	4	FALSE	SEMA3F	SEMA3F	130	0	7	0	0.68076782	FALSE	0	SEMA3F	55712	0.15553272
788423	taxon:9606	3.00866551	2.40E-07	177699	1902	SET domain and mariner transposase fusion gene	gene	biological_process-&-1&-GO:0010452-&&-histone H3-K36 methylation-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0097676-&&-histone H3-K36 dimethylation-%%-GO:2001251-&&-negative regulation of chromosome organization-%%-GO:0000729-&&-DNA double-strand break processing-%%-GO:0015074-&&-DNA integration-%%-GO:0000737-&&-DNA catabolic process, endonucleolytic-%%-GO:0006303-&&-double-strand break repair via nonhomologous end joining-%%-GO:0051568-&&-histone H3-K4 methylation-%%-GO:2000373-&&-positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity-%%-GO:0008283-&&-cell proliferation-%%-GO:0044774-&&-mitotic DNA integrity checkpoint-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:2001034-&&-positive regulation of double-strand break repair via nonhomologous end joining-%%-GO:0031297-&&-replication fork processing|cellular_component-&-1&-GO:0000793-&&-condensed chromosome-%%-GO:0005634-&&-nucleus-%%-GO:0035861-&&-site of double-strand break-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003697-&&-single-stranded DNA binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0000014-&&-single-stranded DNA endodeoxyribonuclease activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0046975-&&-histone methyltransferase activity (H3-K36 specific)-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0044547-&&-DNA topoisomerase binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042800-&&-histone methyltransferase activity (H3-K4 specific)	G:9606:SETMAR			KEGG-&-1&-hsa00310-&&-Lysine degradation	SETMAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SETMAR	0.33237327	0.2	7	5	FALSE	SETMAR	SETMAR	109.8	0	6	0	0.66522241	FALSE	1	SETMAR	420	0.23782609
788458	taxon:9606	2.92358595	3.00E-08	177623	1902	solute carrier family 9 member A2	gene	biological_process-&-1&-GO:0006811-&&-ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0008104-&&-protein localization-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0098719-&&-sodium ion import across plasma membrane-%%-GO:1902600-&&-hydrogen ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015386-&&-potassium:proton antiporter activity-%%-GO:0015385-&&-sodium:proton antiporter activity	G:9606:SLC9A2				SLC9A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC9A2	0.3420457	0.8	7	4	FALSE	SLC9A2	SLC9A2	215.8	0	6	0	0.67940234	FALSE	1	SLC9A2	82	0.28098958
788620	taxon:9606	2.81849693	4.95E-06	160911	1902	MAGE family member B18	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MAGEB18				MAGEB18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEB18	0.35479904	0.04761905	7	4	FALSE	MAGEB18	MAGEB18	222.2857143	0	7	0	0.69691718	FALSE	0	MAGEB18	6848	0.16412698
788621	taxon:9606	2.98534741	1.73E-06	177295	1902	transmembrane BAX inhibitor motif containing 6	gene	biological_process-&-1&-GO:0010523-&&-negative regulation of calcium ion transport into cytosol-%%-GO:1902065-&&-response to L-glutamate-%%-GO:0006986-&&-response to unfolded protein-%%-GO:0070059-&&-intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress-%%-GO:0006914-&&-autophagy-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1990441-&&-negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress-%%-GO:1902236-&&-negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway-%%-GO:0032469-&&-endoplasmic reticulum calcium ion homeostasis-%%-GO:1903298-&&-negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway-%%-GO:0060702-&&-negative regulation of endoribonuclease activity-%%-GO:2001234-&&-negative regulation of apoptotic signaling pathway-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0051025-&&-negative regulation of immunoglobulin secretion-%%-GO:1904721-&&-negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0060698-&&-endoribonuclease inhibitor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:TMBIM6				TMBIM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMBIM6	0.33496939	0.3	7	4	FALSE	TMBIM6	TMBIM6	135.8	0	6	0	0.66910877	FALSE	1	TMBIM6	2072	0.23344828
788729	taxon:9606	2.80352923	1.43E-06	144329	1902	putative inactive beta-glucuronidase-like protein SMA3	gene		G:9606:LOC100653061				LOC100653061	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC100653061	0.35669327	0.28571429	7	4	FALSE	LOC100653061	LOC100653061	257.1428571	0	7	0	0.6994118	FALSE	0	LOC100653061	4046	0.18201133
788767	taxon:9606	2.98219631	3.26E-06	176958	1902	zinc finger protein 227	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF227				ZNF227	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF227	0.33532333	0.04761905	7	5	FALSE	ZNF227	ZNF227	115.8571429	0	7	0	0.66963395	FALSE	0	ZNF227	4128	0.18571429
788781	taxon:9606	2.91334489	4.12E-06	176912	1902	secretogranin II	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0009306-&&-protein secretion-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0043542-&&-endothelial cell migration-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0006954-&&-inflammatory response-%%-GO:0001525-&&-angiogenesis-%%-GO:2001237-&&-negative regulation of extrinsic apoptotic signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0098992-&&-neuronal dense core vesicle|molecular_function-&-1&-GO:0042056-&&-chemoattractant activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005515-&&-protein binding	G:9606:SCG2				SCG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCG2	0.34324807	0.0952381	7	5	FALSE	SCG2	SCG2	138.5714286	0	7	0	0.68110919	FALSE	0	SCG2	6922	0.16484828
788869	taxon:9606	3.11674807	1.20E-05	176728	1902	vasoactive intestinal peptide	gene	biological_process-&-1&-GO:0007589-&&-body fluid secretion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0048255-&&-mRNA stabilization-%%-GO:0010579-&&-positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway-%%-GO:0070459-&&-prolactin secretion-%%-GO:0032880-&&-regulation of protein localization-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0045732-&&-positive regulation of protein catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005184-&&-neuropeptide hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005179-&&-hormone activity	G:9606:VIP			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	VIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VIP	0.32084723	0.04761905	7	5	FALSE	VIP	VIP	59.85714286	0	7	0	0.64720866	FALSE	0	VIP	9398	0.16474333
788921	taxon:9606	2.85662518	1.03E-05	160208	1902	chromosome 6 open reading frame 120	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0035578-&&-azurophil granule lumen	G:9606:C6orf120				C6orf120	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C6orf120	0.35006343	0.0952381	7	4	FALSE	C6orf120	C6orf120	189.7142857	0	7	0	0.69056247	FALSE	0	C6orf120	9092	0.16166056
788926	taxon:9606	2.89396565	9.20E-07	176581	1902	serum deprivation response	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005901-&&-caveola-%%-GO:0045121-&&-membrane raft-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0001786-&&-phosphatidylserine binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0005515-&&-protein binding	G:9606:SDPR				SDPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDPR	0.3455466	0.5	7	5	FALSE	SDPR	SDPR	206.2	0	6	0	0.68433906	FALSE	1	SDPR	1686	0.22936596
788955	taxon:9606	2.81061919	4.89E-06	176539	1902	regulator of G-protein signaling 5	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity	G:9606:RGS5				RGS5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS5	0.35579349	0.42857143	7	4	FALSE	RGS5	RGS5	223.4285714	0	7	0	0.69823013	FALSE	0	RGS5	10692	0.1625078
789008	taxon:9606	2.91507799	8.50E-07	160015	1902	zinc finger protein 829	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF829				ZNF829	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF829	0.343044	0.42857143	7	5	FALSE	ZNF829	ZNF829	160.5714286	0	7	0	0.68082034	FALSE	0	ZNF829	2114	0.1907593
789057	taxon:9606	2.90483693	1.54E-06	176269	1902	cellular repressor of E1A stimulated genes 1	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0008283-&&-cell proliferation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005667-&&-transcription factor complex-%%-GO:0035578-&&-azurophil granule lumen|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0010181-&&-FMN binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0008134-&&-transcription factor binding	G:9606:CREG1				CREG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CREG1	0.3442534	0.14285714	7	5	FALSE	CREG1	CREG1	157.1428571	0	7	0	0.68252718	FALSE	0	CREG1	2696	0.17367257
789186	taxon:9606	2.87915551	2.20E-07	176038	1902	histone cluster 1 H2B family member h	gene	biological_process-&-1&-GO:0006334-&&-nucleosome assembly-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:HIST1H2BH			KEGG-&-1&-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05034-&&-Alcoholism-%%-hsa05203-&&-Viral carcinogenesis	HIST1H2BH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H2BH	0.34732407	0.33333333	7	4	FALSE	HIST1H2BH	HIST1H2BH	300.4285714	0	7	0	0.68680742	FALSE	0	HIST1H2BH	2044	0.26703101
789317	taxon:9606	2.94249252	4.56E-06	175758	1902	carbohydrate sulfotransferase 10	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0016051-&&-carbohydrate biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016232-&&-HNK-1 sulfotransferase activity-%%-GO:0008146-&&-sulfotransferase activity	G:9606:CHST10			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00515-&&-Mannose type O-glycan biosynthesis	CHST10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHST10	0.33984793	0.04761905	7	4	FALSE	CHST10	CHST10	116.8571429	0	7	0	0.67625125	FALSE	0	CHST10	4028	0.15866511
789327	taxon:9606	3.02914763	7.60E-07	175730	1902	harakiri, BCL2 interacting protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0032464-&&-positive regulation of protein homooligomerization-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:HRK			KEGG-&-1&-hsa04210-&&-Apoptosis	HRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HRK	0.33012587	0.38095238	7	5	FALSE	HRK	HRK	72	0	7	0	0.66180873	FALSE	0	HRK	1178	0.19850039
789328	taxon:9606	3.02552387	3.25E-06	175725	1902	tumor necrosis factor superfamily member 9	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006915-&&-apoptotic process-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0045585-&&-positive regulation of cytotoxic T cell differentiation-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0008283-&&-cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005164-&&-tumor necrosis factor receptor binding-%%-GO:0032813-&&-tumor necrosis factor receptor superfamily binding-%%-GO:0005125-&&-cytokine activity	G:9606:TNFSF9			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFSF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFSF9	0.33052127	0.23809524	7	5	FALSE	TNFSF9	TNFSF9	86	0	7	0	0.66241269	FALSE	0	TNFSF9	3360	0.1870526
789373	taxon:9606	2.78887663	5.76E-06	175641	1902	potassium voltage-gated channel subfamily A regulatory beta subunit 3	gene	biological_process-&-1&-GO:0065009-&&-regulation of molecular function-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005249-&&-voltage-gated potassium channel activity	G:9606:KCNAB3				KCNAB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNAB3	0.35856731	0.0952381	7	4	FALSE	KCNAB3	KCNAB3	235.7142857	0	7	0	0.70185389	FALSE	0	KCNAB3	7316	0.16193098
789399	taxon:9606	3.10099259	1.17E-05	175571	1902	G protein-coupled receptor 52	gene	biological_process-&-1&-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0001588-&&-dopamine neurotransmitter receptor activity, coupled via Gs	G:9606:GPR52				GPR52	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPR52	0.32247739	0.04761905	7	5	FALSE	GPR52	GPR52	48.42857143	0	7	0	0.64983457	FALSE	0	GPR52	10182	0.15391705
789444	taxon:9606	3.03781314	1.82E-06	175449	1902	growth differentiation factor 15	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0048468-&&-cell development-%%-GO:0007165-&&-signal transduction-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005515-&&-protein binding	G:9606:GDF15	GDF15	TRUE	KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	GDF15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GDF15	0.32918417	0	7	5	FALSE	GDF15	GDF15	85	0	6	0	0.66036448	FALSE	1	GDF15	1698	0.21052632
789462	taxon:9606	2.93540255	3.02E-06	175412	1902	multiple inositol-polyphosphate phosphatase 1	gene	biological_process-&-1&-GO:0030282-&&-bone mineralization-%%-GO:0001503-&&-ossification-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0006797-&&-polyphosphate metabolic process-%%-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0034417-&&-bisphosphoglycerate 3-phosphatase activity-%%-GO:0052826-&&-inositol hexakisphosphate 2-phosphatase activity-%%-GO:0003993-&&-acid phosphatase activity-%%-GO:0008969-&&-phosphohistidine phosphatase activity-%%-GO:0051717-&&-inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity-%%-GO:0052745-&&-inositol phosphate phosphatase activity-%%-GO:0030351-&&-inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	G:9606:MINPP1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa00562-&&-Inositol phosphate metabolism	MINPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MINPP1	0.34066878	0	7	4	FALSE	MINPP1	MINPP1	125.5714286	0	7	0	0.67743291	FALSE	0	MINPP1	4284	0.15768535
789484	taxon:9606	2.95698755	1.40E-05	175360	1902	G protein subunit alpha 14	gene	biological_process-&-1&-GO:0030168-&&-platelet activation-%%-GO:0060158-&&-phospholipase C-activating dopamine receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0004871-&&-signal transducer activity-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:GNA14			KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05146-&&-Amoebiasis	GNA14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNA14	0.33818201	0.04761905	7	5	FALSE	GNA14	GNA14	114.7142857	0	7	0	0.67383541	FALSE	0	GNA14	15164	0.15405405
789544	taxon:9606	2.83188908	7.00E-07	175224	1902	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0055038-&&-recycling endosome membrane-%%-GO:0016020-&&-membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ACAP1			KEGG-&-1&-hsa04144-&&-Endocytosis	ACAP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAP1	0.35312118	0.28571429	7	4	FALSE	ACAP1	ACAP1	260.4285714	0	7	0	0.69468515	FALSE	0	ACAP1	2176	0.2187913
789567	taxon:9606	2.9502127	1.70E-06	175167	1902	zinc finger protein 518A	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF518A				ZNF518A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF518A	0.33895861	0.04761905	7	4	FALSE	ZNF518A	ZNF518A	103.8571429	0	7	0	0.67496455	FALSE	0	ZNF518A	2416	0.1666282
789582	taxon:9606	2.89270522	1.48E-06	175132	1902	zinc finger BED-type containing 4	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:ZBED4				ZBED4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBED4	0.34569717	0.1	7	5	FALSE	ZBED4	ZBED4	206.8	0	6	0	0.68454913	FALSE	1	ZBED4	3498	0.22609649
789618	taxon:9606	2.86859934	3.02E-06	175045	1902	cyclin D binding myb like transcription factor 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0030154-&&-cell differentiation-%%-GO:0007049-&&-cell cycle-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0044212-&&-transcription regulatory region DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0001135-&&-transcription factor activity, RNA polymerase II transcription factor recruiting-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:DMTF1				DMTF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMTF1	0.34860219	0.0952381	7	4	FALSE	DMTF1	DMTF1	184.7142857	0	7	0	0.68856678	FALSE	0	DMTF1	4578	0.16252679
789627	taxon:9606	2.92720971	1.25E-06	175028	1902	potassium voltage-gated channel subfamily E regulatory subunit 3	gene	biological_process-&-1&-GO:1901387-&&-positive regulation of voltage-gated calcium channel activity-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:1903817-&&-negative regulation of voltage-gated potassium channel activity-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:1905025-&&-negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:1903765-&&-negative regulation of potassium ion export across plasma membrane-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0032809-&&-neuronal cell body membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0043204-&&-perikaryon-%%-GO:0031982-&&-vesicle-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005249-&&-voltage-gated potassium channel activity	G:9606:KCNE3			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	KCNE3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNE3	0.34162226	0.04761905	7	4	FALSE	KCNE3	KCNE3	132.1428571	0	7	0	0.67879838	FALSE	0	KCNE3	2406	0.18103109
789677	taxon:9606	2.80226879	7.40E-06	174913	1902	solute carrier family 30 member 9	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006289-&&-nucleotide-excision repair-%%-GO:0098655-&&-cation transmembrane transport-%%-GO:0006829-&&-zinc II ion transport-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0008324-&&-cation transmembrane transporter activity-%%-GO:0016922-&&-ligand-dependent nuclear receptor binding-%%-GO:0030374-&&-ligand-dependent nuclear receptor transcription coactivator activity-%%-GO:0003682-&&-chromatin binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SLC30A9				SLC30A9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC30A9	0.35685371	0.19047619	7	4	FALSE	SLC30A9	SLC30A9	258.4285714	0	7	0	0.69962187	FALSE	0	SLC30A9	7560	0.18092567
789776	taxon:9606	2.88041594	4.20E-06	174707	1902	zinc finger protein 197	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF197				ZNF197	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF197	0.34717208	0.3	7	5	FALSE	ZNF197	ZNF197	241.2	0	6	0	0.68659734	FALSE	1	ZNF197	4502	0.23747535
790027	taxon:9606	2.80352923	1.43E-06	174066	1902	glucuronidase beta pseudogene	gene		G:9606:SMA4				SMA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMA4	0.35669327	0.28571429	7	4	FALSE	SMA4	SMA4	257.1428571	0	7	0	0.6994118	FALSE	0	SMA4	4046	0.18201133
790112	taxon:9606	2.69576178	1.19E-06	173858	1902	exocyst complex component 6B	gene	biological_process-&-1&-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0015031-&&-protein transport|cellular_component-&-1&-GO:0000145-&&-exocyst|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:EXOC6B				EXOC6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EXOC6B	0.37095266	0.76190476	7	4	FALSE	EXOC6B	EXOC6B	372.5714286	0	7	0	0.71737304	FALSE	0	EXOC6B	3128	0.17852009
790133	taxon:9606	3.03907358	4.13E-06	173798	1902	multimerin 1	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007596-&&-blood coagulation-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031012-&&-extracellular matrix-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MMRN1				MMRN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMRN1	0.32904764	0.04761905	7	5	FALSE	MMRN1	MMRN1	54	0	7	0	0.6601544	FALSE	0	MMRN1	3236	0.14967897
790192	taxon:9606	2.74539152	6.74E-06	173677	1902	AVL9 cell migration associated	gene	biological_process-&-1&-GO:0016477-&&-cell migration|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0055037-&&-recycling endosome	G:9606:AVL9				AVL9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AVL9	0.36424677	0.04761905	7	4	FALSE	AVL9	AVL9	288.5714286	0	7	0	0.70910141	FALSE	0	AVL9	9056	0.16063457
790224	taxon:9606	2.6800063	3.54E-06	173595	1902	lipin 1	gene	biological_process-&-1&-GO:0006642-&&-triglyceride mobilization-%%-GO:0009062-&&-fatty acid catabolic process-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0016311-&&-dephosphorylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0019432-&&-triglyceride biosynthetic process-%%-GO:0007077-&&-mitotic nuclear envelope disassembly-%%-GO:0006646-&&-phosphatidylethanolamine biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005635-&&-nuclear envelope-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0008195-&&-phosphatidate phosphatase activity	G:9606:LPIN1	LPIN1	TRUE	KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04150-&&-mTOR signaling pathway	LPIN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LPIN1	0.37313345	0.19047619	7	4	FALSE	LPIN1	LPIN1	390.7142857	0	7	0	0.71999895	FALSE	0	LPIN1	7090	0.18108932
790293	taxon:9606	3.00409642	5.36E-06	173404	1902	solute carrier family 39 member 6	gene	biological_process-&-1&-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0071578-&&-zinc II ion transmembrane import-%%-GO:0071577-&&-zinc II ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0031258-&&-lamellipodium membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity	G:9606:SLC39A6				SLC39A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A6	0.3328788	0.04761905	7	5	FALSE	SLC39A6	SLC39A6	97.42857143	0	7	0	0.66598393	FALSE	0	SLC39A6	7950	0.17552502
790346	taxon:9606	2.93429967	5.70E-07	173261	1902	CAP-Gly domain containing linker protein 3	gene	biological_process-&-1&-GO:0031115-&&-negative regulation of microtubule polymerization-%%-GO:0018230-&&-peptidyl-L-cysteine S-palmitoylation-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0072321-&&-chaperone-mediated protein transport-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0044091-&&-membrane biogenesis-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:0010803-&&-regulation of tumor necrosis factor-mediated signaling pathway-%%-GO:0010828-&&-positive regulation of glucose transport-%%-GO:0090004-&&-positive regulation of establishment of protein localization to plasma membrane|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0045121-&&-membrane raft-%%-GO:0031901-&&-early endosome membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0005795-&&-Golgi stack-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0035594-&&-ganglioside binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005515-&&-protein binding	G:9606:CLIP3				CLIP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLIP3	0.34079682	0.47619048	7	4	FALSE	CLIP3	CLIP3	136.2857143	0	7	0	0.67761672	FALSE	0	CLIP3	1244	0.19722969
790389	taxon:9606	2.7677643	2.62E-06	173143	1902	testis specific serine kinase 2	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0007286-&&-spermatid development-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007275-&&-multicellular organism development-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005814-&&-centriole-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000287-&&-magnesium ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005524-&&-ATP binding	G:9606:TSSK2				TSSK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSSK2	0.36130244	0.1	7	5	FALSE	TSSK2	TSSK2	362.6	0	6	0	0.70537262	FALSE	1	TSSK2	5772	0.22540473
790414	taxon:9606	2.93146368	1.53E-06	173069	1902	aryl hydrocarbon receptor interacting protein like 1	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0018343-&&-protein farnesylation-%%-GO:0007603-&&-phototransduction, visible light-%%-GO:0030823-&&-regulation of cGMP metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0001895-&&-retina homeostasis|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0001917-&&-photoreceptor inner segment-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0001918-&&-farnesylated protein binding-%%-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:AIPL1			KEGG-&-1&-hsa04934-&&-Cushing syndrome	AIPL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIPL1	0.34112652	0.23809524	7	5	FALSE	AIPL1	AIPL1	134.5714286	0	7	0	0.67808939	FALSE	0	AIPL1	2208	0.18409224
790520	taxon:9606	2.83787616	3.71E-06	172639	1902	ankyrin repeat domain 2	gene	biological_process-&-1&-GO:0001817-&&-regulation of cytokine production-%%-GO:0010832-&&-negative regulation of myotube differentiation-%%-GO:2000291-&&-regulation of myoblast proliferation-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0006936-&&-muscle contraction-%%-GO:1902253-&&-regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0035914-&&-skeletal muscle cell differentiation-%%-GO:0043619-&&-regulation of transcription from RNA polymerase II promoter in response to oxidative stress|cellular_component-&-1&-GO:0030017-&&-sarcomere-%%-GO:0005829-&&-cytosol-%%-GO:0031674-&&-I band-%%-GO:0016605-&&-PML body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus-%%-GO:0000791-&&-euchromatin|molecular_function-&-1&-GO:0008307-&&-structural constituent of muscle-%%-GO:0031432-&&-titin binding-%%-GO:0043422-&&-protein kinase B binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0061629-&&-RNA polymerase II sequence-specific DNA binding transcription factor binding	G:9606:ANKRD2				ANKRD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD2	0.35237619	0.14285714	7	4	FALSE	ANKRD2	ANKRD2	208.8571429	0	7	0	0.69368731	FALSE	0	ANKRD2	4576	0.17068038
790584	taxon:9606	3.06759099	1.72E-05	172075	1902	calcium voltage-gated channel auxiliary subunit gamma 4	gene	biological_process-&-1&-GO:0019226-&&-transmission of nerve impulse-%%-GO:0051899-&&-membrane depolarization-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:2000311-&&-regulation of AMPA receptor activity-%%-GO:0006810-&&-transport-%%-GO:0061337-&&-cardiac conduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0032281-&&-AMPA glutamate receptor complex-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0005891-&&-voltage-gated calcium channel complex|molecular_function-&-1&-GO:0005262-&&-calcium channel activity-%%-GO:0016247-&&-channel regulator activity-%%-GO:0005245-&&-voltage-gated calcium channel activity	G:9606:CACNG4			KEGG-&-1&-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04260-&&-Cardiac muscle contraction-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	CACNG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACNG4	0.3259887	0.14285714	7	5	FALSE	CACNG4	CACNG4	65.85714286	0	7	0	0.6554015	FALSE	0	CACNG4	26772	0.21617786
790588	taxon:9606	3.06428234	1.44E-06	172061	1902	BCL2 binding component 3	gene	biological_process-&-1&-GO:0090200-&&-positive regulation of release of cytochrome c from mitochondria-%%-GO:0097193-&&-intrinsic apoptotic signaling pathway-%%-GO:0006915-&&-apoptotic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0001948-&&-glycoprotein binding-%%-GO:0051117-&&-ATPase binding-%%-GO:0005515-&&-protein binding	G:9606:BBC3			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04115-&&-p53 signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04210-&&-Apoptosis-%%-hsa05200-&&-Pathways in cancer-%%-hsa05210-&&-Colorectal cancer-%%-hsa05016-&&-Huntington disease-%%-hsa01524-&&-Platinum drug resistance	BBC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BBC3	0.32634069	0.38095238	7	5	FALSE	BBC3	BBC3	71	0	7	0	0.65595294	FALSE	0	BBC3	1832	0.20244898
790645	taxon:9606	2.80352923	1.43E-06	155298	1902	glucuronidase, beta pseudogene 3	gene		G:9606:GUSBP3				GUSBP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUSBP3	0.35669327	0.28571429	7	4	FALSE	GUSBP3	GUSBP3	257.1428571	0	7	0	0.6994118	FALSE	0	GUSBP3	4046	0.18201133
790666	taxon:9606	2.87096266	7.16E-06	171544	1902	regulator of cell cycle	gene	biological_process-&-1&-GO:0043537-&&-negative regulation of blood vessel endothelial cell migration-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0071850-&&-mitotic cell cycle arrest-%%-GO:2000573-&&-positive regulation of DNA biosynthetic process-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:1901991-&&-negative regulation of mitotic cell cycle phase transition-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0032967-&&-positive regulation of collagen biosynthetic process-%%-GO:0090272-&&-negative regulation of fibroblast growth factor production-%%-GO:0001100-&&-negative regulation of exit from mitosis-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:1901203-&&-positive regulation of extracellular matrix assembly-%%-GO:0050710-&&-negative regulation of cytokine secretion-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0003331-&&-positive regulation of extracellular matrix constituent secretion-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0072537-&&-fibroblast activation-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:2000048-&&-negative regulation of cell-cell adhesion mediated by cadherin-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0006956-&&-complement activation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:RGCC				RGCC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGCC	0.34831522	0.14285714	7	4	FALSE	RGCC	RGCC	184.8571429	0	7	0	0.68817289	FALSE	0	RGCC	5468	0.18690235
790781	taxon:9606	2.97936033	4.86E-06	171230	1902	SCAN domain containing 1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0042802-&&-identical protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity	G:9606:SCAND1				SCAND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAND1	0.33564252	0.28571429	7	5	FALSE	SCAND1	SCAND1	92.71428571	0	7	0	0.67010661	FALSE	0	SCAND1	3734	0.16180504
790835	taxon:9606	3.07089964	2.73E-06	171004	1902	fumarylacetoacetate hydrolase domain containing 2A	gene	biological_process-&-1&-GO:0008152-&&-metabolic process|molecular_function-&-1&-GO:0016787-&&-hydrolase activity-%%-GO:0046872-&&-metal ion binding	G:9606:FAHD2A				FAHD2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAHD2A	0.32563747	0.14285714	7	5	FALSE	FAHD2A	FAHD2A	70.42857143	0	7	0	0.65485006	FALSE	0	FAHD2A	2802	0.15421003
790855	taxon:9606	2.90798803	4.73E-06	170887	1902	syntrophin gamma 1	gene	biological_process-&-1&-GO:0007154-&&-cell communication|cellular_component-&-1&-GO:0005856-&&-cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0032587-&&-ruffle membrane-%%-GO:0016013-&&-syntrophin complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0008022-&&-protein C-terminus binding	G:9606:SNTG1				SNTG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNTG1	0.34388037	0.04761905	7	4	FALSE	SNTG1	SNTG1	134	0	7	0	0.682002	FALSE	0	SNTG1	5668	0.15516381
790900	taxon:9606	2.90184339	1.27E-06	170736	1902	JNK1/MAPK8-associated membrane protein	gene	biological_process-&-1&-GO:0006986-&&-response to unfolded protein-%%-GO:0030433-&&-ER-associated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:JKAMP				JKAMP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JKAMP	0.34460854	0.38095238	7	5	FALSE	JKAMP	JKAMP	158.4285714	0	7	0	0.6830261	FALSE	0	JKAMP	2586	0.18726781
790922	taxon:9606	2.73609579	1.15E-05	170698	1902	neuroblastoma amplified sequence	gene	biological_process-&-1&-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0015031-&&-protein transport-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:2000623-&&-negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070939-&&-Dsl1/NZR complex-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0000149-&&-SNARE binding	G:9606:NBAS	NBAS	TRUE		NBAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBAS	0.36548428	0.38095238	7	4	FALSE	NBAS	NBAS	300.8571429	0	7	0	0.7106507	FALSE	0	NBAS	10582	0.16201246
790936	taxon:9606	3.21569245	6.84E-06	154286	1902	C-C motif chemokine receptor 2	gene	biological_process-&-1&-GO:0043310-&&-negative regulation of eosinophil degranulation-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0090265-&&-positive regulation of immune complex clearance by monocytes and macrophages-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0009611-&&-response to wounding-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0019725-&&-cellular homeostasis-%%-GO:0002407-&&-dendritic cell chemotaxis-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:2000473-&&-positive regulation of hematopoietic stem cell migration-%%-GO:0002827-&&-positive regulation of T-helper 1 type immune response-%%-GO:0032743-&&-positive regulation of interleukin-2 production-%%-GO:0006935-&&-chemotaxis-%%-GO:2000439-&&-positive regulation of monocyte extravasation-%%-GO:0042535-&&-positive regulation of tumor necrosis factor biosynthetic process-%%-GO:0006954-&&-inflammatory response-%%-GO:0007259-&&-JAK-STAT cascade-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006968-&&-cellular defense response-%%-GO:0046641-&&-positive regulation of alpha-beta T cell proliferation-%%-GO:2000451-&&-positive regulation of CD8-positive, alpha-beta T cell extravasation-%%-GO:0016032-&&-viral process-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0050870-&&-positive regulation of T cell activation-%%-GO:0006955-&&-immune response-%%-GO:0035705-&&-T-helper 17 cell chemotaxis-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0090026-&&-positive regulation of monocyte chemotaxis-%%-GO:2000464-&&-positive regulation of astrocyte chemotaxis-%%-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0002829-&&-negative regulation of type 2 immune response-%%-GO:0010574-&&-regulation of vascular endothelial growth factor production|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005829-&&-cytosol-%%-GO:0043204-&&-perikaryon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0004950-&&-chemokine receptor activity-%%-GO:0016493-&&-C-C chemokine receptor activity-%%-GO:0031727-&&-CCR2 chemokine receptor binding	G:9606:CCR2			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCR2	0.31097501	0.28571429	7	5	FALSE	CCR2	CCR2	30	0	7	0	0.63071792	FALSE	0	CCR2	13660	0.18072289
790952	taxon:9606	2.87757996	4.50E-07	170626	1902	cytidine/uridine monophosphate kinase 1	gene	biological_process-&-1&-GO:0046940-&&-nucleoside monophosphate phosphorylation-%%-GO:0006222-&&-UMP biosynthetic process-%%-GO:0006207-&&-'de novo' pyrimidine nucleobase biosynthetic process-%%-GO:0009142-&&-nucleoside triphosphate biosynthetic process-%%-GO:0009220-&&-pyrimidine ribonucleotide biosynthetic process-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0050145-&&-nucleoside phosphate kinase activity-%%-GO:0004127-&&-cytidylate kinase activity-%%-GO:0004849-&&-uridine kinase activity-%%-GO:0004550-&&-nucleoside diphosphate kinase activity-%%-GO:0009041-&&-uridylate kinase activity	G:9606:CMPK1			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways	CMPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMPK1	0.34751424	0.19047619	7	5	FALSE	CMPK1	CMPK1	188.5714286	0	7	0	0.68707001	FALSE	0	CMPK1	1660	0.18427312
790953	taxon:9606	3.15960296	1.72E-05	170620	1902	ghrelin and obestatin prepropeptide	gene	biological_process-&-1&-GO:0042536-&&-negative regulation of tumor necrosis factor biosynthetic process-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0001696-&&-gastric acid secretion-%%-GO:0060399-&&-positive regulation of growth hormone receptor signaling pathway-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0045409-&&-negative regulation of interleukin-6 biosynthetic process-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0042322-&&-negative regulation of circadian sleep/wake cycle, REM sleep-%%-GO:0032095-&&-regulation of response to food-%%-GO:0032691-&&-negative regulation of interleukin-1 beta production-%%-GO:0016358-&&-dendrite development-%%-GO:0032100-&&-positive regulation of appetite-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0009725-&&-response to hormone-%%-GO:0008343-&&-adult feeding behavior-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0051464-&&-positive regulation of cortisol secretion-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0051461-&&-positive regulation of corticotropin secretion-%%-GO:2000507-&&-positive regulation of energy homeostasis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0008154-&&-actin polymerization or depolymerization-%%-GO:0046010-&&-positive regulation of circadian sleep/wake cycle, non-REM sleep-%%-GO:2000506-&&-negative regulation of energy homeostasis-%%-GO:0040013-&&-negative regulation of locomotion-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0043627-&&-response to estrogen-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0043400-&&-cortisol secretion-%%-GO:0051216-&&-cartilage development-%%-GO:0030252-&&-growth hormone secretion-%%-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0046697-&&-decidualization-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0060079-&&-excitatory postsynaptic potential|cellular_component-&-1&-GO:0034774-&&-secretory granule lumen-%%-GO:0030424-&&-axon-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0098794-&&-postsynapse-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0031768-&&-ghrelin receptor binding-%%-GO:0030296-&&-protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0016608-&&-growth hormone-releasing hormone activity	G:9606:GHRL	GHRL	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GHRL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GHRL	0.31649546	0.0952381	7	5	FALSE	GHRL	GHRL	40.57142857	0	7	0	0.64006617	FALSE	0	GHRL	9700	0.15034778
791043	taxon:9606	2.94375295	3.56E-06	170265	1902	ADP-ribosylhydrolase like 2	gene	biological_process-&-1&-GO:0071451-&&-cellular response to superoxide|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0004649-&&-poly(ADP-ribose) glycohydrolase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ADPRHL2				ADPRHL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADPRHL2	0.33970242	0	7	5	FALSE	ADPRHL2	ADPRHL2	117.2857143	0	7	0	0.67604117	FALSE	0	ADPRHL2	3566	0.15587897
791049	taxon:9606	2.97479124	5.14E-06	170237	1902	cancer/testis antigen 55	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CT55				CT55	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CT55	0.33615804	0.0952381	7	5	FALSE	CT55	CT55	96.28571429	0	7	0	0.67086813	FALSE	0	CT55	3732	0.15460829
791077	taxon:9606	3.00708996	1.70E-06	170124	1902	prolyl 3-hydroxylase 2	gene	biological_process-&-1&-GO:0019511-&&-peptidyl-proline hydroxylation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032963-&&-collagen metabolic process|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005604-&&-basement membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0031418-&&-L-ascorbic acid binding-%%-GO:0019797-&&-procollagen-proline 3-dioxygenase activity-%%-GO:0005506-&&-iron ion binding	G:9606:P3H2				P3H2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P3H2	0.33254742	0.04761905	7	5	FALSE	P3H2	P3H2	97.57142857	0	7	0	0.66548501	FALSE	0	P3H2	2180	0.16786333
791142	taxon:9606	2.93099102	8.56E-06	169892	1902	protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)	gene	biological_process-&-1&-GO:0006493-&&-protein O-linked glycosylation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0047223-&&-beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity-%%-GO:0008375-&&-acetylglucosaminyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:POMGNT1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00515-&&-Mannose type O-glycan biosynthesis	POMGNT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POMGNT1	0.34118153	0	7	4	FALSE	POMGNT1	POMGNT1	108	0	7	0	0.67816816	FALSE	0	POMGNT1	7840	0.15091678
791167	taxon:9606	2.78777375	1.50E-07	169837	1902	lysine demethylase 4D	gene	biological_process-&-1&-GO:0033169-&&-histone H3-K9 demethylation-%%-GO:0000724-&&-double-strand break repair via homologous recombination-%%-GO:0035563-&&-positive regulation of chromatin binding-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:2001034-&&-positive regulation of double-strand break repair via nonhomologous end joining-%%-GO:1900113-&&-negative regulation of histone H3-K9 trimethylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0071479-&&-cellular response to ionizing radiation|cellular_component-&-1&-GO:0072562-&&-blood microparticle-%%-GO:0005721-&&-pericentric heterochromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0035861-&&-site of double-strand break|molecular_function-&-1&-GO:0003684-&&-damaged DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0032454-&&-histone demethylase activity (H3-K9 specific)-%%-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity-%%-GO:0032452-&&-histone demethylase activity	G:9606:KDM4D				KDM4D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KDM4D	0.35870917	0.5	7	4	FALSE	KDM4D	KDM4D	384.6	0	6	0	0.70203771	FALSE	1	KDM4D	558	0.25071708
791266	taxon:9606	2.80463211	1.61E-06	169437	1902	proline rich 12	gene	cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005634-&&-nucleus-%%-GO:0030054-&&-cell junction-%%-GO:0014069-&&-postsynaptic density-%%-GO:0045211-&&-postsynaptic membrane	G:9606:PRR12				PRR12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRR12	0.356553	0.19047619	7	4	FALSE	PRR12	PRR12	243.4285714	0	7	0	0.69922798	FALSE	0	PRR12	3652	0.17231953
791267	taxon:9606	2.81881204	5.13E-06	169432	1902	neurolysin	gene	biological_process-&-1&-GO:0006111-&&-regulation of gluconeogenesis-%%-GO:0006518-&&-peptide metabolic process-%%-GO:0006508-&&-proteolysis-%%-GO:1902809-&&-regulation of skeletal muscle fiber differentiation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0005758-&&-mitochondrial intermembrane space|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0046872-&&-metal ion binding	G:9606:NLN			KEGG-&-1&-hsa04614-&&-Renin-angiotensin system	NLN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLN	0.35475938	0.04761905	7	4	FALSE	NLN	NLN	207	0	7	0	0.69686466	FALSE	0	NLN	7304	0.15475297
791379	taxon:9606	2.94170474	1.22E-06	168886	1902	RAP2C, member of RAS oncogene family	gene	biological_process-&-1&-GO:0030336-&&-negative regulation of cell migration-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0090557-&&-establishment of endothelial intestinal barrier-%%-GO:0030033-&&-microvillus assembly-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:1903506-&&-regulation of nucleic acid-templated transcription-%%-GO:0032486-&&-Rap protein signal transduction-%%-GO:0061097-&&-regulation of protein tyrosine kinase activity|cellular_component-&-1&-GO:0044291-&&-cell-cell contact zone-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003713-&&-transcription coactivator activity-%%-GO:0005525-&&-GTP binding-%%-GO:0019003-&&-GDP binding	G:9606:RAP2C			KEGG-&-1&-hsa04530-&&-Tight junction	RAP2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAP2C	0.33993894	0.0952381	7	5	FALSE	RAP2C	RAP2C	135	0	7	0	0.67638254	FALSE	0	RAP2C	2210	0.17480959
791439	taxon:9606	2.71340791	1.23E-06	168641	1902	serine/threonine kinase 33	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:STK33				STK33	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK33	0.36854024	0.33333333	7	4	FALSE	STK33	STK33	359	0	7	0	0.71443202	FALSE	0	STK33	6380	0.18717414
791459	taxon:9606	2.95163069	2.82E-06	168557	1902	proline rich and Gla domain 4	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005509-&&-calcium ion binding	G:9606:PRRG4				PRRG4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRRG4	0.33879577	0	7	5	FALSE	PRRG4	PRRG4	115.2857143	0	7	0	0.67472822	FALSE	0	PRRG4	4534	0.15807153
791487	taxon:9606	3.23113282	2.53E-06	168431	1902	popeye domain containing 2	gene	biological_process-&-1&-GO:0002027-&&-regulation of heart rate-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:POPDC2				POPDC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POPDC2	0.30948898	0	7	5	FALSE	POPDC2	POPDC2	15.71428571	0	7	0	0.62814453	FALSE	0	POPDC2	2008	0.15014577
791507	taxon:9606	2.98487474	9.10E-07	168349	1902	hypoxia inducible factor 3 alpha subunit	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006915-&&-apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0061418-&&-regulation of transcription from RNA polymerase II promoter in response to hypoxia-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:HIF3A				HIF3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIF3A	0.33502243	0.76190476	7	5	FALSE	HIF3A	HIF3A	107.8571429	0	7	0	0.66918754	FALSE	0	HIF3A	1470	0.17857143
791537	taxon:9606	2.79470616	3.87E-05	168203	1902	N-acetylglucosamine-1-phosphate transferase alpha and beta subunits	gene	biological_process-&-1&-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0033299-&&-secretion of lysosomal enzymes-%%-GO:0016256-&&-N-glycan processing to lysosome-%%-GO:0007040-&&-lysosome organization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0003976-&&-UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:GNPTAB			KEGG-&-1&-hsa04142-&&-Lysosome	GNPTAB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GNPTAB	0.35781937	0.0952381	7	5	FALSE	GNPTAB	GNPTAB	231	0	7	0	0.70088231	FALSE	0	GNPTAB	27106	0.1566382
791603	taxon:9606	2.59886561	1.29E-05	167863	1902	fructosamine 3 kinase related protein	gene	biological_process-&-1&-GO:0043687-&&-post-translational protein modification-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016301-&&-kinase activity	G:9606:FN3KRP				FN3KRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FN3KRP	0.38478327	0.33333333	7	4	FALSE	FN3KRP	FN3KRP	552.4285714	0	7	0	0.7335224	FALSE	0	FN3KRP	10928	0.21026004
791619	taxon:9606	2.92437372	1.50E-06	167786	1902	zinc finger MYM-type containing 1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0003677-&&-DNA binding	G:9606:ZMYM1				ZMYM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZMYM1	0.34195356	0.04761905	7	4	FALSE	ZMYM1	ZMYM1	117.5714286	0	7	0	0.67927105	FALSE	0	ZMYM1	2286	0.15727745
791653	taxon:9606	2.92894281	3.83E-06	167569	1902	integral membrane protein 2C	gene	biological_process-&-1&-GO:2001238-&&-positive regulation of extrinsic apoptotic signaling pathway-%%-GO:0030182-&&-neuron differentiation-%%-GO:0010977-&&-negative regulation of neuron projection development|cellular_component-&-1&-GO:0005764-&&-lysosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0001540-&&-beta-amyloid binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:ITM2C				ITM2C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITM2C	0.34142012	0	7	5	FALSE	ITM2C	ITM2C	151	0	7	0	0.67850953	FALSE	0	ITM2C	5594	0.16910936
791685	taxon:9606	2.95163069	6.79E-06	167441	1902	tweety family member 3	gene	biological_process-&-1&-GO:0006821-&&-chloride transport-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0034707-&&-chloride channel complex|molecular_function-&-1&-GO:0005254-&&-chloride channel activity-%%-GO:0005229-&&-intracellular calcium activated chloride channel activity	G:9606:TTYH3				TTYH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTYH3	0.33879577	0.0952381	7	4	FALSE	TTYH3	TTYH3	105.5714286	0	7	0	0.67472822	FALSE	0	TTYH3	5872	0.15692964
791695	taxon:9606	2.90105562	4.70E-06	167393	1902	glutamate receptor interacting protein 2	gene	cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0030159-&&-receptor signaling complex scaffold activity	G:9606:GRIP2				GRIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRIP2	0.34470211	0.28571429	7	5	FALSE	GRIP2	GRIP2	173.8571429	0	7	0	0.6831574	FALSE	0	GRIP2	4488	0.1960058
791719	taxon:9606	2.81235229	1.85E-06	167205	1902	interferon stimulated exonuclease gene 20 like 2	gene	biological_process-&-1&-GO:0090503-&&-RNA phosphodiester bond hydrolysis, exonucleolytic-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0000175-&&-3'-5'-exoribonuclease activity-%%-GO:0005515-&&-protein binding	G:9606:ISG20L2				ISG20L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISG20L2	0.35557423	0.66666667	7	5	FALSE	ISG20L2	ISG20L2	310.1428571	0	7	0	0.69794128	FALSE	0	ISG20L2	7586	0.23162275
791724	taxon:9606	2.847487	1.61E-06	167195	1902	Cdk5 and Abl enzyme substrate 2	gene	biological_process-&-1&-GO:0051726-&&-regulation of cell cycle-%%-GO:0051301-&&-cell division-%%-GO:0007049-&&-cell cycle	G:9606:CABLES2				CABLES2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CABLES2	0.35118685	0.5	7	4	FALSE	CABLES2	CABLES2	270.6	0	6	0	0.6920855	FALSE	1	CABLES2	2244	0.22512479
791829	taxon:9606	2.83724594	1.54E-06	166646	1902	BUD13 homolog	gene	biological_process-&-1&-GO:0006406-&&-mRNA export from nucleus-%%-GO:0000398-&&-mRNA splicing, via spliceosome|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070274-&&-RES complex|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005515-&&-protein binding	G:9606:BUD13				BUD13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BUD13	0.35245446	0.14285714	7	5	FALSE	BUD13	BUD13	219.7142857	0	7	0	0.69379234	FALSE	0	BUD13	2862	0.1772722
792018	taxon:9606	2.92799748	1.26E-06	166343	1902	arrestin domain containing 4	gene	biological_process-&-1&-GO:0051443-&&-positive regulation of ubiquitin-protein transferase activity|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ARRDC4				ARRDC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRDC4	0.34153035	0.33333333	7	4	FALSE	ARRDC4	ARRDC4	161.8571429	0	7	0	0.67866709	FALSE	0	ARRDC4	1758	0.1980042
792032	taxon:9606	3.07357807	2.20E-05	182711	1902	bone morphogenetic protein 3	gene	biological_process-&-1&-GO:0001649-&&-osteoblast differentiation-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0051216-&&-cartilage development-%%-GO:0001501-&&-skeletal system development-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0048468-&&-cell development-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0070700-&&-BMP receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity	G:9606:BMP3			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	BMP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BMP3	0.3253537	0.14285714	7	5	FALSE	BMP3	BMP3	63.28571429	0	7	0	0.65440366	FALSE	0	BMP3	26306	0.1627907
792048	taxon:9606	2.9585631	2.59E-06	166307	1902	secretoglobin family 3A member 1	gene	biological_process-&-1&-GO:1901741-&&-positive regulation of myoblast fusion-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005125-&&-cytokine activity	G:9606:SCGB3A1				SCGB3A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCGB3A1	0.33800192	0.14285714	7	5	FALSE	SCGB3A1	SCGB3A1	106	0	7	0	0.67357282	FALSE	0	SCGB3A1	3440	0.16868571
792054	taxon:9606	2.84417835	1.86E-05	182680	1902	betacellulin	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:BTC			KEGG-&-1&-hsa04012-&&-ErbB signaling pathway	BTC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTC	0.35159539	0.19047619	7	4	FALSE	BTC	BTC	199.1428571	0	7	0	0.69263694	FALSE	0	BTC	16130	0.16684659
792128	taxon:9606	2.92973058	8.30E-07	166164	1902	coiled-coil domain containing 97	gene	cellular_component-&-1&-GO:0005686-&&-U2 snRNP	G:9606:CCDC97				CCDC97	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC97	0.34132831	0.33333333	7	5	FALSE	CCDC97	CCDC97	147.1428571	0	7	0	0.67837824	FALSE	0	CCDC97	1730	0.19047619
792161	taxon:9606	2.93902631	2.64E-05	182496	1902	adenylate cyclase 9	gene	biological_process-&-1&-GO:0034199-&&-activation of protein kinase A activity-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0006171-&&-cAMP biosynthetic process-%%-GO:0071880-&&-adenylate cyclase-activating adrenergic receptor signaling pathway-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007165-&&-signal transduction-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0003091-&&-renal water homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004016-&&-adenylate cyclase activity-%%-GO:0004383-&&-guanylate cyclase activity	G:9606:ADCY9			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04961-&&-Endocrine and other factor-regulated calcium reabsorption-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa04970-&&-Salivary secretion	ADCY9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADCY9	0.34024874	0	7	4	FALSE	ADCY9	ADCY9	116.7142857	0	7	0	0.67682895	FALSE	0	ADCY9	20758	0.15679443
792210	taxon:9606	2.9404443	1.33E-06	182404	1902	zinc finger homeobox 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0007517-&&-muscle organ development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007420-&&-brain development-%%-GO:0032922-&&-circadian regulation of gene expression-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071559-&&-response to transforming growth factor beta-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:1904059-&&-regulation of locomotor rhythm|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005667-&&-transcription factor complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ZFHX3			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	ZFHX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFHX3	0.34008466	0.0952381	7	5	FALSE	ZFHX3	ZFHX3	117.7142857	0	7	0	0.67659262	FALSE	0	ZFHX3	2616	0.15937804
792318	taxon:9606	2.82086025	1.20E-06	165858	1902	tumor protein p53 inducible nuclear protein 1	gene	biological_process-&-1&-GO:0000045-&&-autophagosome assembly-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0006915-&&-apoptotic process-%%-GO:0009408-&&-response to heat-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048102-&&-autophagic cell death-%%-GO:0071447-&&-cellular response to hydroperoxide-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0072703-&&-cellular response to methyl methanesulfonate-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:1904761-&&-negative regulation of myofibroblast differentiation-%%-GO:2001235-&&-positive regulation of apoptotic signaling pathway-%%-GO:0048147-&&-negative regulation of fibroblast proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0034644-&&-cellular response to UV-%%-GO:0006950-&&-response to stress-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0098869-&&-cellular oxidant detoxification|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016605-&&-PML body-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005634-&&-nucleus-%%-GO:0005776-&&-autophagosome-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0016209-&&-antioxidant activity	G:9606:TP53INP1				TP53INP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53INP1	0.35450179	0.38095238	7	4	FALSE	TP53INP1	TP53INP1	224.5714286	0	7	0	0.69652329	FALSE	0	TP53INP1	2642	0.17314682
792349	taxon:9606	2.82999842	2.38E-06	165792	1902	family with sequence similarity 129 member A	gene	biological_process-&-1&-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045727-&&-positive regulation of translation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:FAM129A				FAM129A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM129A	0.35335709	0.14285714	7	4	FALSE	FAM129A	FAM129A	218	0	7	0	0.69500026	FALSE	0	FAM129A	4152	0.17183448
792365	taxon:9606	2.90058295	1.37E-06	165770	1902	mediator complex subunit 12 like	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0016592-&&-mediator complex|molecular_function-&-1&-GO:0001105-&&-RNA polymerase II transcription coactivator activity-%%-GO:0008013-&&-beta-catenin binding	G:9606:MED12L			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway	MED12L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MED12L	0.34475828	0.19047619	7	5	FALSE	MED12L	MED12L	155.4285714	0	7	0	0.68323617	FALSE	0	MED12L	2636	0.16881704
792402	taxon:9606	3.01528281	0	182085	1902	crystallin beta B2	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0050896-&&-response to stimulus-%%-GO:0043010-&&-camera-type eye development|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005212-&&-structural constituent of eye lens-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0042802-&&-identical protein binding	G:9606:CRYBB2				CRYBB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRYBB2	0.33164385	1	7	5	FALSE	CRYBB2	CRYBB2	102.4	0	6	0	0.66411953	FALSE	1	CRYBB2	0	0.21694915
792454	taxon:9606	3.14920435	1.04E-05	181994	1902	cathepsin S	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus-%%-GO:2001259-&&-positive regulation of cation channel activity-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0010447-&&-response to acidic pH-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0006508-&&-proteolysis-%%-GO:0034769-&&-basement membrane disassembly-%%-GO:0002250-&&-adaptive immune response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0048002-&&-antigen processing and presentation of peptide antigen-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0016485-&&-protein processing-%%-GO:0051603-&&-proteolysis involved in cellular protein catabolic process-%%-GO:0006955-&&-immune response-%%-GO:0019882-&&-antigen processing and presentation|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0036021-&&-endolysosome lumen-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005764-&&-lysosome-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004197-&&-cysteine-type endopeptidase activity-%%-GO:0005518-&&-collagen binding-%%-GO:0001968-&&-fibronectin binding-%%-GO:0043236-&&-laminin binding-%%-GO:0043394-&&-proteoglycan binding	G:9606:CTSS			KEGG-&-1&-hsa04612-&&-Antigen processing and presentation-%%-hsa04210-&&-Apoptosis-%%-hsa04145-&&-Phagosome-%%-hsa05152-&&-Tuberculosis-%%-hsa04142-&&-Lysosome	CTSS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTSS	0.31754052	0.04761905	7	5	FALSE	CTSS	CTSS	38.71428571	0	7	0	0.64179928	FALSE	0	CTSS	9254	0.15322581
792480	taxon:9606	2.73089649	2.78E-06	165564	1902	kelch like family member 32	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0007286-&&-spermatid development-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0008584-&&-male gonad development|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL32				KLHL32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL32	0.36618012	0.0952381	7	5	FALSE	KLHL32	KLHL32	310.7142857	0	7	0	0.71151725	FALSE	0	KLHL32	9168	0.17153919
792482	taxon:9606	2.70946904	5.08E-06	165566	1902	serine/threonine kinase 11 interacting protein	gene	biological_process-&-1&-GO:0043312-&&-neutrophil degranulation-%%-GO:0008104-&&-protein localization|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0019901-&&-protein kinase binding	G:9606:STK11IP				STK11IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK11IP	0.369076	0	7	4	FALSE	STK11IP	STK11IP	326.4285714	0	7	0	0.71508849	FALSE	0	STK11IP	8752	0.16628951
792514	taxon:9606	3.00126044	4.18E-06	181868	1902	calcitonin receptor	gene	biological_process-&-1&-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0072659-&&-protein localization to plasma membrane-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0015031-&&-protein transport-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0045762-&&-positive regulation of adenylate cyclase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0032841-&&-calcitonin binding-%%-GO:0008565-&&-protein transporter activity-%%-GO:0004872-&&-receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004948-&&-calcitonin receptor activity	G:9606:CALCR			KEGG-&-1&-hsa04380-&&-Osteoclast differentiation-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CALCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CALCR	0.33319334	0.14285714	7	5	FALSE	CALCR	CALCR	74.71428571	0	7	0	0.66645659	FALSE	0	CALCR	4416	0.16801032
792585	taxon:9606	2.97242792	3.89E-06	181766	1902	CD7 molecule	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0042110-&&-T cell activation-%%-GO:0002250-&&-adaptive immune response-%%-GO:0048873-&&-homeostasis of number of cells within a tissue-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004872-&&-receptor activity	G:9606:CD7			KEGG-&-1&-hsa04640-&&-Hematopoietic cell lineage	CD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD7	0.33642532	0.04761905	7	4	FALSE	CD7	CD7	79.42857143	0	7	0	0.67126201	FALSE	0	CD7	3212	0.15284327
792628	taxon:9606	2.88372459	3.69E-06	181692	1902	endothelin receptor type B	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0048484-&&-enteric nervous system development-%%-GO:0086100-&&-endothelin receptor signaling pathway-%%-GO:0030318-&&-melanocyte differentiation-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0060406-&&-positive regulation of penile erection-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0007399-&&-nervous system development-%%-GO:0001755-&&-neural crest cell migration-%%-GO:0042311-&&-vasodilation-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0048265-&&-response to pain-%%-GO:0007568-&&-aging-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042310-&&-vasoconstriction-%%-GO:0014826-&&-vein smooth muscle contraction-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:0019934-&&-cGMP-mediated signaling-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007497-&&-posterior midgut development-%%-GO:0032269-&&-negative regulation of cellular protein metabolic process-%%-GO:0014043-&&-negative regulation of neuron maturation-%%-GO:0042045-&&-epithelial fluid transport-%%-GO:0048246-&&-macrophage chemotaxis-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0035645-&&-enteric smooth muscle cell differentiation-%%-GO:0031620-&&-regulation of fever generation-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0006885-&&-regulation of pH-%%-GO:0035815-&&-positive regulation of renal sodium excretion|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0031702-&&-type 1 angiotensin receptor binding-%%-GO:0004962-&&-endothelin receptor activity-%%-GO:0017046-&&-peptide hormone binding	G:9606:EDNRB	EDNRB	TRUE	KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04022-&&-cGMP-PKG signaling pathway	EDNRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EDNRB	0.34677375	0.0952381	7	4	FALSE	EDNRB	EDNRB	146	0	7	0	0.6860459	FALSE	0	EDNRB	4892	0.15504112
792644	taxon:9606	2.9735308	2.17E-05	181649	1902	ectonucleoside triphosphate diphosphohydrolase 6 (putative)	gene	biological_process-&-1&-GO:0032026-&&-response to magnesium ion-%%-GO:0055086-&&-nucleobase-containing small molecule metabolic process-%%-GO:0051592-&&-response to calcium ion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0017110-&&-nucleoside-diphosphatase activity-%%-GO:0017111-&&-nucleoside-triphosphatase activity-%%-GO:0008894-&&-guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity-%%-GO:0045134-&&-uridine-diphosphatase activity	G:9606:ENTPD6			KEGG-&-1&-hsa00240-&&-Pyrimidine metabolism-%%-hsa00230-&&-Purine metabolism	ENTPD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENTPD6	0.33630054	0	7	5	FALSE	ENTPD6	ENTPD6	95.14285714	0	7	0	0.6710782	FALSE	0	ENTPD6	15732	0.15233472
792697	taxon:9606	2.67401922	1.14E-06	165166	1902	ankyrin repeat domain 13B	gene	cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005770-&&-late endosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle	G:9606:ANKRD13B				ANKRD13B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD13B	0.37396889	0.23809524	7	4	FALSE	ANKRD13B	ANKRD13B	411	0	7	0	0.7209968	FALSE	0	ANKRD13B	3874	0.19158723
792739	taxon:9606	2.81896959	2.43E-06	165077	1902	F-box protein 27	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0019005-&&-SCF ubiquitin ligase complex|molecular_function-&-1&-GO:0001948-&&-glycoprotein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO27				FBXO27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO27	0.35473955	0.33333333	7	4	FALSE	FBXO27	FBXO27	263.8571429	0	7	0	0.6968384	FALSE	0	FBXO27	3394	0.19390756
792884	taxon:9606	2.91523554	3.62E-06	181220	1902	EYA transcriptional coactivator and phosphatase 1	gene	biological_process-&-1&-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0034613-&&-cellular protein localization-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0072513-&&-positive regulation of secondary heart field cardioblast proliferation-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0016576-&&-histone dephosphorylation-%%-GO:0060487-&&-lung epithelial cell differentiation-%%-GO:0045664-&&-regulation of neuron differentiation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0030154-&&-cell differentiation-%%-GO:0014706-&&-striated muscle tissue development-%%-GO:0035909-&&-aorta morphogenesis-%%-GO:0001656-&&-metanephros development-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0016925-&&-protein sumoylation-%%-GO:0042473-&&-outer ear morphogenesis-%%-GO:0007501-&&-mesodermal cell fate specification-%%-GO:0060037-&&-pharyngeal system development-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0048665-&&-neuron fate specification-%%-GO:0071600-&&-otic vesicle morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0042474-&&-middle ear morphogenesis-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0048752-&&-semicircular canal morphogenesis-%%-GO:0006302-&&-double-strand break repair-%%-GO:0007389-&&-pattern specification process-%%-GO:0035088-&&-establishment or maintenance of apical/basal cell polarity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0032993-&&-protein-DNA complex-%%-GO:0043234-&&-protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:EYA1			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	EYA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EYA1	0.34302546	0.04761905	7	4	FALSE	EYA1	EYA1	133	0	7	0	0.68079408	FALSE	0	EYA1	4372	0.15842601
792893	taxon:9606	3.32204191	1.36E-06	181205	1902	coagulation factor IX	gene	biological_process-&-1&-GO:0007596-&&-blood coagulation-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0006465-&&-signal peptide processing-%%-GO:0007598-&&-blood coagulation, extrinsic pathway-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0006508-&&-proteolysis-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0031638-&&-zymogen activation|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005796-&&-Golgi lumen|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:F9			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	F9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-F9	0.30101968	0.4	7	5	FALSE	F9	F9	26.6	0	6	0	0.61299302	FALSE	1	F9	764	0.23539823
792906	taxon:9606	2.79045218	6.64E-06	164796	1902	discoidin, CUB and LCCL domain containing 2	gene	biological_process-&-1&-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030522-&&-intracellular receptor signaling pathway-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DCBLD2				DCBLD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCBLD2	0.35836486	0.14285714	7	4	FALSE	DCBLD2	DCBLD2	257.1428571	0	7	0	0.7015913	FALSE	0	DCBLD2	7078	0.17215626
792977	taxon:9606	3.06412478	2.78E-06	181059	1902	forkhead box D4	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0008301-&&-DNA binding, bending-%%-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:FOXD4				FOXD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FOXD4	0.32635747	0	7	5	FALSE	FOXD4	FOXD4	52.71428571	0	7	0	0.6559792	FALSE	0	FOXD4	2462	0.15529816
793113	taxon:9606	2.78966441	1.30E-06	164320	1902	F-box and leucine rich repeat protein 14	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXL14				FBXL14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL14	0.35846606	0.23809524	7	4	FALSE	FBXL14	FBXL14	323.5714286	0	7	0	0.7017226	FALSE	0	FBXL14	3426	0.21784752
793250	taxon:9606	2.86938711	1.65E-05	180446	1902	glypican 1	gene	biological_process-&-1&-GO:2001016-&&-positive regulation of skeletal muscle cell differentiation-%%-GO:0050900-&&-leukocyte migration-%%-GO:0032288-&&-myelin assembly-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0014037-&&-Schwann cell differentiation-%%-GO:0030200-&&-heparan sulfate proteoglycan catabolic process-%%-GO:0007411-&&-axon guidance-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0040037-&&-negative regulation of fibroblast growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005768-&&-endosome-%%-GO:0005796-&&-Golgi lumen-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005829-&&-cytosol-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0043395-&&-heparan sulfate proteoglycan binding-%%-GO:0043236-&&-laminin binding	G:9606:GPC1			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer-%%-hsa05418-&&-Fluid shear stress and atherosclerosis	GPC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPC1	0.34850648	0	7	5	FALSE	GPC1	GPC1	166.8571429	0	7	0	0.68843548	FALSE	0	GPC1	13896	0.14742857
793252	taxon:9606	2.86639357	4.07E-06	180440	1902	glycoprotein M6B	gene	biological_process-&-1&-GO:0085029-&&-extracellular matrix assembly-%%-GO:0007399-&&-nervous system development-%%-GO:0015031-&&-protein transport-%%-GO:2000009-&&-negative regulation of protein localization to cell surface-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0030501-&&-positive regulation of bone mineralization-%%-GO:0001503-&&-ossification-%%-GO:0030154-&&-cell differentiation-%%-GO:0051612-&&-negative regulation of serotonin uptake-%%-GO:0051893-&&-regulation of focal adhesion assembly|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:GPM6B				GPM6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPM6B	0.34887044	0	7	5	FALSE	GPM6B	GPM6B	186.4285714	0	7	0	0.6889344	FALSE	0	GPM6B	8418	0.16735431
793262	taxon:9606	2.73231448	6.77E-06	180409	1902	guanylate cyclase 1 soluble subunit alpha	gene	biological_process-&-1&-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0052565-&&-response to defense-related host nitric oxide production-%%-GO:0060087-&&-relaxation of vascular smooth muscle-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0030828-&&-positive regulation of cGMP biosynthetic process-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004016-&&-adenylate cyclase activity-%%-GO:0004383-&&-guanylate cyclase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0004872-&&-receptor activity	G:9606:GUCY1A3			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04713-&&-Circadian entrainment-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	GUCY1A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUCY1A3	0.36599008	0.28571429	7	4	FALSE	GUCY1A3	GUCY1A3	343.7142857	0	7	0	0.71128092	FALSE	0	GUCY1A3	5292	0.18805223
793271	taxon:9606	2.96644084	1.44E-06	164008	1902	family with sequence similarity 187 member B	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:FAM187B				FAM187B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM187B	0.33710431	0	7	5	FALSE	FAM187B	FAM187B	98.14285714	0	7	0	0.67225986	FALSE	0	FAM187B	2130	0.1756652
793280	taxon:9606	2.79076729	4.36E-06	180383	1902	histone cluster 1 H1 family member t	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0006334-&&-nucleosome assembly-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0000786-&&-nucleosome|molecular_function-&-1&-GO:0003677-&&-DNA binding	G:9606:HIST1H1T				HIST1H1T	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HIST1H1T	0.35832439	0.14285714	7	4	FALSE	HIST1H1T	HIST1H1T	264.4285714	0	7	0	0.70153878	FALSE	0	HIST1H1T	5600	0.17703945
793316	taxon:9606	3.02032456	8.60E-07	180326	1902	hemochromatosis	gene	biological_process-&-1&-GO:2000008-&&-regulation of protein localization to cell surface-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0006953-&&-acute-phase response-%%-GO:0097421-&&-liver regeneration-%%-GO:0060586-&&-multicellular organismal iron ion homeostasis-%%-GO:0048260-&&-positive regulation of receptor-mediated endocytosis-%%-GO:2000059-&&-negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0071281-&&-cellular response to iron ion-%%-GO:0090277-&&-positive regulation of peptide hormone secretion-%%-GO:0007565-&&-female pregnancy-%%-GO:0002626-&&-negative regulation of T cell antigen processing and presentation-%%-GO:1990641-&&-response to iron ion starvation-%%-GO:0006461-&&-protein complex assembly-%%-GO:0010039-&&-response to iron ion-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0019882-&&-antigen processing and presentation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:1900122-&&-positive regulation of receptor binding-%%-GO:1900121-&&-negative regulation of receptor binding-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0002474-&&-antigen processing and presentation of peptide antigen via MHC class I-%%-GO:0010106-&&-cellular response to iron ion starvation-%%-GO:1904437-&&-positive regulation of transferrin receptor binding-%%-GO:2000272-&&-negative regulation of receptor activity-%%-GO:1903991-&&-positive regulation of ferrous iron import into cell-%%-GO:0032092-&&-positive regulation of protein binding-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0002725-&&-negative regulation of T cell cytokine production-%%-GO:1904283-&&-negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I-%%-GO:0042446-&&-hormone biosynthetic process-%%-GO:1904434-&&-positive regulation of ferrous iron binding-%%-GO:0097459-&&-iron ion import into cell-%%-GO:0032435-&&-negative regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:2001186-&&-negative regulation of CD8-positive, alpha-beta T cell activation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:1990712-&&-HFE-transferrin receptor complex-%%-GO:0005886-&&-plasma membrane-%%-GO:1990357-&&-terminal web-%%-GO:0005769-&&-early endosome-%%-GO:0045177-&&-apical part of cell-%%-GO:0055037-&&-recycling endosome-%%-GO:0045178-&&-basal part of cell-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0042612-&&-MHC class I protein complex-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005102-&&-receptor binding-%%-GO:0042605-&&-peptide antigen binding-%%-GO:0030881-&&-beta-2-microglobulin binding-%%-GO:0039706-&&-co-receptor binding-%%-GO:0003823-&&-antigen binding-%%-GO:1990459-&&-transferrin receptor binding	G:9606:HFE	HFE	TRUE		HFE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HFE	0.33109025	0.2	7	5	FALSE	HFE	HFE	89	0	6	0	0.66327924	FALSE	1	HFE	1378	0.21715686
793338	taxon:9606	2.82952576	2.53E-06	180287	1902	major histocompatibility complex, class II, DR beta 4	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0050852-&&-T cell receptor signaling pathway-%%-GO:0060333-&&-interferon-gamma-mediated signaling pathway|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0012507-&&-ER to Golgi transport vesicle membrane-%%-GO:0031902-&&-late endosome membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030658-&&-transport vesicle membrane-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0030669-&&-clathrin-coated endocytic vesicle membrane-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0071556-&&-integral component of lumenal side of endoplasmic reticulum membrane-%%-GO:0042613-&&-MHC class II protein complex	G:9606:HLA-DRB4			KEGG-&-1&-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04612-&&-Antigen processing and presentation-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa04145-&&-Phagosome-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa05416-&&-Viral myocarditis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa05323-&&-Rheumatoid arthritis	HLA-DRB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HLA-DRB4	0.35341611	0.19047619	7	4	FALSE	HLA-DRB4	HLA-DRB4	233.5714286	0	7	0	0.69507904	FALSE	0	HLA-DRB4	3752	0.18547562
793369	taxon:9606	3.04742398	4.86E-06	180230	1902	integrin subunit alpha 9	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0042060-&&-wound healing-%%-GO:0007155-&&-cell adhesion-%%-GO:0007229-&&-integrin-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0034679-&&-integrin alpha9-beta1 complex-%%-GO:0008305-&&-integrin complex-%%-GO:0009925-&&-basal plasma membrane|molecular_function-&-1&-GO:0005518-&&-collagen binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0043236-&&-laminin binding	G:9606:ITGA9			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa05410-&&-Hypertrophic cardiomyopathy (HCM)-%%-hsa04510-&&-Focal adhesion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05412-&&-Arrhythmogenic right ventricular cardiomyopathy (ARVC)-%%-hsa05165-&&-Human papillomavirus infection	ITGA9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGA9	0.328146	0.2	7	5	FALSE	ITGA9	ITGA9	84.4	0	6	0	0.65876267	FALSE	1	ITGA9	4458	0.21932115
787060	taxon:9606	2.78997952	1.10E-07	163766	1902	coiled-coil domain containing 117	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC117				CCDC117	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC117	0.35842557	0.46666667	6	4	FALSE	CCDC117	CCDC117	348.8333333	0	6	0	0.70167008	FALSE	0	CCDC117	636	0.23244444
787120	taxon:9606	3.44714038	1.10E-06	180030	1902	interleukin 12A	gene	biological_process-&-1&-GO:0042832-&&-defense response to protozoan-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:0016477-&&-cell migration-%%-GO:0098586-&&-cellular response to virus-%%-GO:0097191-&&-extrinsic apoptotic signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0050671-&&-positive regulation of lymphocyte proliferation-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0051135-&&-positive regulation of NK T cell activation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:2000510-&&-positive regulation of dendritic cell chemotaxis-%%-GO:0009615-&&-response to virus-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0006955-&&-immune response-%%-GO:0010224-&&-response to UV-B-%%-GO:0032946-&&-positive regulation of mononuclear cell proliferation-%%-GO:0034393-&&-positive regulation of smooth muscle cell apoptotic process-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042520-&&-positive regulation of tyrosine phosphorylation of Stat4 protein-%%-GO:0045582-&&-positive regulation of T cell differentiation-%%-GO:0045954-&&-positive regulation of natural killer cell mediated cytotoxicity-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0032816-&&-positive regulation of natural killer cell activation-%%-GO:0032700-&&-negative regulation of interleukin-17 production-%%-GO:0002860-&&-positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target-%%-GO:0032729-&&-positive regulation of interferon-gamma production|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0043514-&&-interleukin-12 complex|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0045513-&&-interleukin-27 binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005143-&&-interleukin-12 receptor binding-%%-GO:0042163-&&-interleukin-12 beta subunit binding	G:9606:IL12A			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05330-&&-Allograft rejection-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05168-&&-Herpes simplex infection-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05146-&&-Amoebiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa05144-&&-Malaria	IL12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL12A	0.29009553	0.16666667	6	5	FALSE	IL12A	IL12A	20.5	0	5	0	0.59214327	FALSE	1	IL12A	552	0.26315789
787135	taxon:9606	2.94548606	7.31E-06	180004	1902	inhibin alpha subunit	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030509-&&-BMP signaling pathway-%%-GO:0046882-&&-negative regulation of follicle-stimulating hormone secretion-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0030218-&&-erythrocyte differentiation-%%-GO:0009605-&&-response to external stimulus-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007399-&&-nervous system development-%%-GO:0008584-&&-male gonad development-%%-GO:0001501-&&-skeletal system development-%%-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0045650-&&-negative regulation of macrophage differentiation-%%-GO:0045077-&&-negative regulation of interferon-gamma biosynthetic process-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0042541-&&-hemoglobin biosynthetic process-%%-GO:0030154-&&-cell differentiation-%%-GO:0042326-&&-negative regulation of phosphorylation-%%-GO:0046881-&&-positive regulation of follicle-stimulating hormone secretion-%%-GO:0045578-&&-negative regulation of B cell differentiation-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0048468-&&-cell development-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0043513-&&-inhibin B complex-%%-GO:0043512-&&-inhibin A complex-%%-GO:0034673-&&-inhibin-betaglycan-ActRII complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0001917-&&-photoreceptor inner segment|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0034711-&&-inhibin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005102-&&-receptor binding	G:9606:INHA	INHA	TRUE	KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	INHA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INHA	0.33950254	0.13333333	6	5	FALSE	INHA	INHA	116	0	6	0	0.67575232	FALSE	0	INHA	5716	0.18301688
787230	taxon:9606	2.9550969	4.70E-07	179824	1902	INSM transcriptional repressor 1	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0003310-&&-pancreatic A cell differentiation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0003358-&&-noradrenergic neuron development-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0042421-&&-norepinephrine biosynthetic process-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0060290-&&-transdifferentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0043254-&&-regulation of protein complex assembly-%%-GO:0003309-&&-type B pancreatic cell differentiation-%%-GO:0031018-&&-endocrine pancreas development-%%-GO:0007049-&&-cell cycle-%%-GO:0061549-&&-sympathetic ganglion development-%%-GO:0003323-&&-type B pancreatic cell development-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0061104-&&-adrenal chromaffin cell differentiation-%%-GO:0071158-&&-positive regulation of cell cycle arrest|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0017053-&&-transcriptional repressor complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0031490-&&-chromatin DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042826-&&-histone deacetylase binding-%%-GO:0001047-&&-core promoter binding-%%-GO:0030332-&&-cyclin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:INSM1				INSM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSM1	0.33839838	0.2	6	5	FALSE	INSM1	INSM1	162.3333333	0	6	0	0.67415052	FALSE	0	INSM1	1132	0.22761369
787284	taxon:9606	3.2138018	6.70E-07	179746	1902	potassium voltage-gated channel subfamily J member 5	gene	biological_process-&-1&-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:1990573-&&-potassium ion import across plasma membrane-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0010107-&&-potassium ion import-%%-GO:0006813-&&-potassium ion transport-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:0098914-&&-membrane repolarization during atrial cardiac muscle cell action potential-%%-GO:0099625-&&-ventricular cardiac muscle cell membrane repolarization|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0030315-&&-T-tubule|molecular_function-&-1&-GO:0015467-&&-G-protein activated inward rectifier potassium channel activity-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0005242-&&-inward rectifier potassium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0086089-&&-voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	G:9606:KCNJ5	KCNJ5	TRUE	KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05032-&&-Morphine addiction-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04713-&&-Circadian entrainment-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04915-&&-Estrogen signaling pathway	KCNJ5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNJ5	0.31115796	0.5	6	5	FALSE	KCNJ5	KCNJ5	74.25	0	5	0	0.63103303	FALSE	1	KCNJ5	698	0.26902174
787334	taxon:9606	2.81109185	1.13E-06	179646	1902	keratin 81	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT81				KRT81	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT81	0.35573366	0.2	6	5	FALSE	KRT81	KRT81	281.8333333	0	6	0	0.69815136	FALSE	0	KRT81	3610	0.20295602
787352	taxon:9606	3.18150307	6.04E-06	179610	1902	methylenetetrahydrofolate reductase	gene	biological_process-&-1&-GO:0046655-&&-folic acid metabolic process-%%-GO:0070555-&&-response to interleukin-1-%%-GO:0006555-&&-methionine metabolic process-%%-GO:0046500-&&-S-adenosylmethionine metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0035999-&&-tetrahydrofolate interconversion-%%-GO:0051593-&&-response to folic acid-%%-GO:0042493-&&-response to drug-%%-GO:0001666-&&-response to hypoxia-%%-GO:0033274-&&-response to vitamin B2-%%-GO:0070829-&&-heterochromatin maintenance-%%-GO:0031060-&&-regulation of histone methylation-%%-GO:0050667-&&-homocysteine metabolic process-%%-GO:0043200-&&-response to amino acid-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0045202-&&-synapse-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0072341-&&-modified amino acid binding-%%-GO:0004489-&&-methylenetetrahydrofolate reductase (NAD(P)H) activity-%%-GO:0032403-&&-protein complex binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0050661-&&-NADP binding	G:9606:MTHFR	MTHFR	TRUE	KEGG-&-1&-hsa00670-&&-One carbon pool by folate-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa01523-&&-Antifolate resistance	MTHFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFR	0.31431684	0	6	5	FALSE	MTHFR	MTHFR	41.33333333	0	6	0	0.63641615	FALSE	0	MTHFR	6170	0.18005952
787428	taxon:9606	3.07688672	6.84E-06	179449	1902	leptin	gene	biological_process-&-1&-GO:0045639-&&-positive regulation of myeloid cell differentiation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0046850-&&-regulation of bone remodeling-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0001525-&&-angiogenesis-%%-GO:0032760-&&-positive regulation of tumor necrosis factor production-%%-GO:0019953-&&-sexual reproduction-%%-GO:0033210-&&-leptin-mediated signaling pathway-%%-GO:0060612-&&-adipose tissue development-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007565-&&-female pregnancy-%%-GO:0038108-&&-negative regulation of appetite by leptin-mediated signaling pathway-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:1900015-&&-regulation of cytokine production involved in inflammatory response-%%-GO:0050901-&&-leukocyte tethering or rolling-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0008343-&&-adult feeding behavior-%%-GO:0006909-&&-phagocytosis-%%-GO:0061037-&&-negative regulation of cartilage development-%%-GO:0030300-&&-regulation of intestinal cholesterol absorption-%%-GO:2000491-&&-positive regulation of hepatic stellate cell activation-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0032817-&&-regulation of natural killer cell proliferation-%%-GO:0010507-&&-negative regulation of autophagy-%%-GO:0070093-&&-negative regulation of glucagon secretion-%%-GO:0072606-&&-interleukin-8 secretion-%%-GO:0007260-&&-tyrosine phosphorylation of STAT protein-%%-GO:0032008-&&-positive regulation of TOR signaling-%%-GO:0033686-&&-positive regulation of luteinizing hormone secretion-%%-GO:1904651-&&-positive regulation of fat cell apoptotic process-%%-GO:0090335-&&-regulation of brown fat cell differentiation-%%-GO:0001542-&&-ovulation from ovarian follicle-%%-GO:0060587-&&-regulation of lipoprotein lipid oxidation-%%-GO:0071298-&&-cellular response to L-ascorbic acid-%%-GO:0043270-&&-positive regulation of ion transport-%%-GO:0045906-&&-negative regulation of vasoconstriction-%%-GO:0050810-&&-regulation of steroid biosynthetic process-%%-GO:0001666-&&-response to hypoxia-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0006111-&&-regulation of gluconeogenesis-%%-GO:0001890-&&-placenta development-%%-GO:0033197-&&-response to vitamin E-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0032355-&&-response to estradiol-%%-GO:0046628-&&-positive regulation of insulin receptor signaling pathway-%%-GO:0048639-&&-positive regulation of developmental growth-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0042269-&&-regulation of natural killer cell mediated cytotoxicity-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0007623-&&-circadian rhythm-%%-GO:0035360-&&-positive regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:1990051-&&-activation of protein kinase C activity-%%-GO:0003300-&&-cardiac muscle hypertrophy-%%-GO:0021954-&&-central nervous system neuron development-%%-GO:0006635-&&-fatty acid beta-oxidation-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042755-&&-eating behavior-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0042445-&&-hormone metabolic process-%%-GO:0008206-&&-bile acid metabolic process-%%-GO:0030217-&&-T cell differentiation-%%-GO:0035630-&&-bone mineralization involved in bone maturation-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0002021-&&-response to dietary excess-%%-GO:0014823-&&-response to activity-%%-GO:0032310-&&-prostaglandin secretion-%%-GO:0010888-&&-negative regulation of lipid storage-%%-GO:0046881-&&-positive regulation of follicle-stimulating hormone secretion-%%-GO:0030073-&&-insulin secretion-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0006114-&&-glycerol biosynthetic process-%%-GO:0032868-&&-response to insulin-%%-GO:0032814-&&-regulation of natural killer cell activation-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0032615-&&-interleukin-12 production-%%-GO:0098868-&&-bone growth-%%-GO:0045471-&&-response to ethanol-%%-GO:0001936-&&-regulation of endothelial cell proliferation-%%-GO:0044320-&&-cellular response to leptin stimulus-%%-GO:0032099-&&-negative regulation of appetite-%%-GO:2000366-&&-positive regulation of STAT protein import into nucleus-%%-GO:0072604-&&-interleukin-6 secretion-%%-GO:2000486-&&-negative regulation of glutamine transport-%%-GO:0050892-&&-intestinal absorption|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0051428-&&-peptide hormone receptor binding	G:9606:LEP	LEP	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	LEP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LEP	0.32500384	0.06666667	6	5	FALSE	LEP	LEP	48.66666667	0	6	0	0.65385221	FALSE	0	LEP	5830	0.17518248
787491	taxon:9606	2.8972743	2.50E-06	162962	1902	heat shock protein family A (Hsp70) member 12A	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003674-&&-molecular_function	G:9606:HSPA12A				HSPA12A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSPA12A	0.34515199	0.13333333	6	4	FALSE	HSPA12A	HSPA12A	227.5	0	6	0	0.68378762	FALSE	0	HSPA12A	7354	0.22587065
787504	taxon:9606	3.6601544	4.70E-07	179330	1902	matrix metallopeptidase 10	gene	biological_process-&-1&-GO:0030334-&&-regulation of cell migration-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:MMP10				MMP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP10	0.27321252	0.5	6	5	FALSE	MMP10	MMP10	20	0	5	0	0.55664093	FALSE	1	MMP10	336	0.30769231
787590	taxon:9606	2.98865606	1.09E-06	179131	1902	neurogenin 1	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0031536-&&-positive regulation of exit from mitosis-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0007399-&&-nervous system development-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045165-&&-cell fate commitment-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030182-&&-neuron differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045666-&&-positive regulation of neuron differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0000989-&&-transcription factor activity, transcription factor binding-%%-GO:0005515-&&-protein binding-%%-GO:0070888-&&-E-box binding-%%-GO:0003677-&&-DNA binding	G:9606:NEUROG1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	NEUROG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEUROG1	0.33459856	0.26666667	6	5	FALSE	NEUROG1	NEUROG1	118.3333333	0	6	0	0.66855732	FALSE	0	NEUROG1	1634	0.19403394
787801	taxon:9606	2.79911769	1.97E-06	162381	1902	sidekick cell adhesion molecule 1	gene	biological_process-&-1&-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0007416-&&-synapse assembly-%%-GO:0060998-&&-regulation of dendritic spine development-%%-GO:0010842-&&-retina layer formation-%%-GO:0048148-&&-behavioral response to cocaine|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030054-&&-cell junction-%%-GO:0045202-&&-synapse|molecular_function-&-1&-GO:0042802-&&-identical protein binding	G:9606:SDK1				SDK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDK1	0.35725543	0.06666667	6	4	FALSE	SDK1	SDK1	284	0	6	0	0.70014705	FALSE	0	SDK1	4908	0.19703292
787988	taxon:9606	2.78793131	1.10E-06	162060	1902	orofacial cleft 1 candidate 1	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:OFCC1				OFCC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OFCC1	0.3586889	0.2	6	4	FALSE	OFCC1	OFCC1	306.8333333	0	6	0	0.70201145	FALSE	0	OFCC1	3256	0.20135697
788001	taxon:9606	2.99889712	1.30E-06	178430	1902	ectonucleotide pyrophosphatase/phosphodiesterase 1	gene	biological_process-&-1&-GO:0031214-&&-biomineral tissue development-%%-GO:0009143-&&-nucleoside triphosphate catabolic process-%%-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0046325-&&-negative regulation of glucose import-%%-GO:0045599-&&-negative regulation of fat cell differentiation-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0045719-&&-negative regulation of glycogen biosynthetic process-%%-GO:0006771-&&-riboflavin metabolic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0030505-&&-inorganic diphosphate transport-%%-GO:0046627-&&-negative regulation of insulin receptor signaling pathway-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0006955-&&-immune response-%%-GO:0030730-&&-sequestering of triglyceride-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0030643-&&-cellular phosphate ion homeostasis|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0009986-&&-cell surface-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004528-&&-phosphodiesterase I activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005158-&&-insulin receptor binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0050656-&&-3'-phosphoadenosine 5'-phosphosulfate binding-%%-GO:0005515-&&-protein binding-%%-GO:0047429-&&-nucleoside-triphosphate diphosphatase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0004551-&&-nucleotide diphosphatase activity-%%-GO:0030247-&&-polysaccharide binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0035529-&&-NADH pyrophosphatase activity-%%-GO:0005044-&&-scavenger receptor activity	G:9606:ENPP1	ENPP1	TRUE	KEGG-&-1&-hsa00770-&&-Pantothenate and CoA biosynthesis-%%-hsa00740-&&-Riboflavin metabolism-%%-hsa00240-&&-Pyrimidine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	ENPP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENPP1	0.33345592	0.13333333	6	4	FALSE	ENPP1	ENPP1	88.66666667	0	6	0	0.66685048	FALSE	0	ENPP1	1588	0.18104038
788034	taxon:9606	2.81818182	2.99E-06	161944	1902	serine/threonine kinase 32C	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:STK32C				STK32C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK32C	0.35483871	0.26666667	6	5	FALSE	STK32C	STK32C	286.5	0	6	0	0.6969697	FALSE	0	STK32C	3162	0.21131611
788042	taxon:9606	2.85079565	1.85E-06	161929	1902	mohawk homeobox	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007517-&&-muscle organ development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding	G:9606:MKX				MKX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MKX	0.35077926	0.33333333	6	5	FALSE	MKX	MKX	246.3333333	0	6	0	0.69153406	FALSE	0	MKX	3460	0.2041183
788089	taxon:9606	2.9056247	1.47E-06	178257	1902	progastricsin	gene	biological_process-&-1&-GO:0007586-&&-digestion-%%-GO:0002803-&&-positive regulation of antibacterial peptide production-%%-GO:0030163-&&-protein catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004190-&&-aspartic-type endopeptidase activity	G:9606:PGC				PGC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGC	0.34416007	0.33333333	6	5	FALSE	PGC	PGC	260	0	5	0	0.68239588	FALSE	1	PGC	3074	0.27900107
788093	taxon:9606	3.4857413	0	178255	1902	placental growth factor	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0001525-&&-angiogenesis-%%-GO:0002040-&&-sprouting angiogenesis-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0060688-&&-regulation of morphogenesis of a branching structure-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030154-&&-cell differentiation-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0001666-&&-response to hypoxia-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046982-&&-protein heterodimerization activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005172-&&-vascular endothelial growth factor receptor binding-%%-GO:0008201-&&-heparin binding	G:9606:PGF	PGF	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer	PGF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGF	0.28688302	1	6	5	FALSE	PGF	PGF	24.75	0	5	0	0.58570978	FALSE	1	PGF	0	0.309375
788097	taxon:9606	3.06412478	6.30E-07	178247	1902	phosphoglucomutase 5	gene	biological_process-&-1&-GO:0019388-&&-galactose catabolic process-%%-GO:0006006-&&-glucose metabolic process-%%-GO:0007155-&&-cell adhesion-%%-GO:0005978-&&-glycogen biosynthetic process|cellular_component-&-1&-GO:0005914-&&-spot adherens junction-%%-GO:0042383-&&-sarcolemma-%%-GO:0005829-&&-cytosol-%%-GO:0009898-&&-cytoplasmic side of plasma membrane-%%-GO:0014704-&&-intercalated disc-%%-GO:0016010-&&-dystrophin-associated glycoprotein complex-%%-GO:0005913-&&-cell-cell adherens junction-%%-GO:0030018-&&-Z disc-%%-GO:0043034-&&-costamere-%%-GO:0001725-&&-stress fiber-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0004614-&&-phosphoglucomutase activity	G:9606:PGM5				PGM5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PGM5	0.32635747	0.2	6	5	FALSE	PGM5	PGM5	94.66666667	0	6	0	0.6559792	FALSE	0	PGM5	1034	0.21537291
788105	taxon:9606	2.81833937	2.40E-07	161844	1902	cysteine rich PAK1 inhibitor	gene	biological_process-&-1&-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0043627-&&-response to estrogen-%%-GO:0051493-&&-regulation of cytoskeleton organization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CRIPAK				CRIPAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CRIPAK	0.35481887	0.26666667	6	4	FALSE	CRIPAK	CRIPAK	312	0	6	0	0.69694344	FALSE	0	CRIPAK	1296	0.22984267
788145	taxon:9606	3.22010399	3.96E-06	178166	1902	PZP, alpha-2-macroglobulin like	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0007565-&&-female pregnancy|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity	G:9606:PZP				PZP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PZP	0.31054898	0.2	6	5	FALSE	PZP	PZP	45.33333333	0	6	0	0.62998267	FALSE	0	PZP	2532	0.19067797
788164	taxon:9606	2.92421617	2.92E-06	161758	1902	cyclin dependent kinase like 4	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0051726-&&-regulation of cell cycle|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity	G:9606:CDKL4				CDKL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKL4	0.34197198	0.13333333	6	5	FALSE	CDKL4	CDKL4	156	0	6	0	0.67929731	FALSE	0	CDKL4	4128	0.19413233
788355	taxon:9606	3.15534898	3.10E-05	177818	1902	C-X-C motif chemokine ligand 11	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0043950-&&-positive regulation of cAMP-mediated signaling-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0030816-&&-positive regulation of cAMP metabolic process-%%-GO:0006935-&&-chemotaxis-%%-GO:0007165-&&-signal transduction-%%-GO:0010818-&&-T cell chemotaxis-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0002690-&&-positive regulation of leukocyte chemotaxis-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0006954-&&-inflammatory response|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0048248-&&-CXCR3 chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding	G:9606:CXCL11	CXCL11	TRUE	KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCL11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL11	0.31692216	0	6	5	FALSE	CXCL11	CXCL11	62.16666667	0	6	0	0.64077517	FALSE	0	CXCL11	36206	0.17426401
788361	taxon:9606	2.8359855	3.38E-06	177807	1902	stromal cell derived factor 2	gene	biological_process-&-1&-GO:0006486-&&-protein glycosylation-%%-GO:0035269-&&-protein O-linked mannosylation-%%-GO:0071712-&&-ER-associated misfolded protein catabolic process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004169-&&-dolichyl-phosphate-mannose-protein mannosyltransferase activity	G:9606:SDF2				SDF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SDF2	0.35261111	0.13333333	6	4	FALSE	SDF2	SDF2	222.1666667	0	6	0	0.69400242	FALSE	0	SDF2	4758	0.18153301
788412	taxon:9606	3.24074366	9.30E-07	177716	1902	sulfotransferase family 2B member 1	gene	biological_process-&-1&-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0000103-&&-sulfate assimilation-%%-GO:0008202-&&-steroid metabolic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0004027-&&-alcohol sulfotransferase activity-%%-GO:0050294-&&-steroid sulfotransferase activity-%%-GO:0005515-&&-protein binding	G:9606:SULT2B1			KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis	SULT2B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SULT2B1	0.30857115	0	6	5	FALSE	SULT2B1	SULT2B1	37	0	5	0	0.62654272	FALSE	1	SULT2B1	612	0.26086957
788415	taxon:9606	3.03497715	1.49E-06	177714	1902	sulfotransferase family 2A member 1	gene	biological_process-&-1&-GO:0030573-&&-bile acid catabolic process-%%-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0007586-&&-digestion-%%-GO:0051923-&&-sulfation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0047704-&&-bile-salt sulfotransferase activity-%%-GO:0050294-&&-steroid sulfotransferase activity-%%-GO:0004062-&&-aryl sulfotransferase activity-%%-GO:0004304-&&-estrone sulfotransferase activity-%%-GO:0008146-&&-sulfotransferase activity-%%-GO:0005515-&&-protein binding	G:9606:SULT2A1	SULT2A1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa04976-&&-Bile secretion-%%-hsa05204-&&-Chemical carcinogenesis	SULT2A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SULT2A1	0.32949177	0	6	5	FALSE	SULT2A1	SULT2A1	101.75	0	5	0	0.66083714	FALSE	1	SULT2A1	1420	0.25899743
788452	taxon:9606	2.84165748	9.90E-07	177645	1902	smoothelin	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0006939-&&-smooth muscle contraction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0008307-&&-structural constituent of muscle	G:9606:SMTN				SMTN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMTN	0.3519073	0.06666667	6	4	FALSE	SMTN	SMTN	231.1666667	0	6	0	0.69305709	FALSE	0	SMTN	2482	0.19096935
788485	taxon:9606	2.76130455	2.01E-06	177561	1902	small nuclear RNA activating complex polypeptide 3	gene	biological_process-&-1&-GO:0042795-&&-snRNA transcription from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006383-&&-transcription from RNA polymerase III promoter-%%-GO:0009301-&&-snRNA transcription-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:SNAPC3				SNAPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNAPC3	0.36214767	0.13333333	6	4	FALSE	SNAPC3	SNAPC3	319.1666667	0	6	0	0.70644924	FALSE	0	SNAPC3	4002	0.19395415
788539	taxon:9606	2.83850638	6.15E-06	161090	1902	myosin light chain kinase family member 4	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004687-&&-myosin light chain kinase activity	G:9606:MYLK4			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MYLK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYLK4	0.35229796	0.13333333	6	4	FALSE	MYLK4	MYLK4	259.6666667	0	6	0	0.69358227	FALSE	0	MYLK4	7478	0.208166
788550	taxon:9606	3.05766504	8.80E-07	144691	1902	FPGT-TNNI3K readthrough	gene		G:9606:FPGT-TNNI3K				FPGT-TNNI3K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FPGT-TNNI3K	0.32704694	0.06666667	6	5	FALSE	FPGT-TNNI3K	FPGT-TNNI3K	54.5	0	6	0	0.65705583	FALSE	0	FPGT-TNNI3K	1044	0.1922619
788585	taxon:9606	2.80384434	1.49E-06	177393	1902	contactin 2	gene	biological_process-&-1&-GO:0010954-&&-positive regulation of protein processing-%%-GO:0097090-&&-presynaptic membrane organization-%%-GO:0031133-&&-regulation of axon diameter-%%-GO:0007612-&&-learning-%%-GO:0021853-&&-cerebral cortex GABAergic interneuron migration-%%-GO:0071205-&&-protein localization to juxtaparanode region of axon-%%-GO:0007628-&&-adult walking behavior-%%-GO:0048710-&&-regulation of astrocyte differentiation-%%-GO:0071206-&&-establishment of protein localization to juxtaparanode region of axon-%%-GO:0007413-&&-axonal fasciculation-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0045163-&&-clustering of voltage-gated potassium channels-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0060168-&&-positive regulation of adenosine receptor signaling pathway-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0007411-&&-axon guidance-%%-GO:0031623-&&-receptor internalization-%%-GO:0007155-&&-cell adhesion-%%-GO:0022010-&&-central nervous system myelination|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0043209-&&-myelin sheath-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0044224-&&-juxtaparanode region of axon-%%-GO:0033268-&&-node of Ranvier-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0043621-&&-protein self-association	G:9606:CNTN2			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)	CNTN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNTN2	0.35665318	0.33333333	6	5	FALSE	CNTN2	CNTN2	275	0	6	0	0.69935928	FALSE	0	CNTN2	2080	0.1961694
788648	taxon:9606	3.14558059	1.90E-06	177255	1902	trefoil factor 3	gene	biological_process-&-1&-GO:0006952-&&-defense response-%%-GO:0042060-&&-wound healing-%%-GO:0007586-&&-digestion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:TFF3				TFF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TFF3	0.31790634	0	6	5	FALSE	TFF3	TFF3	68.5	0	5	0	0.64240324	FALSE	1	TFF3	1218	0.25471698
788701	taxon:9606	2.9683315	8.70E-07	177159	1902	transition protein 1	gene	biological_process-&-1&-GO:0006338-&&-chromatin remodeling-%%-GO:0035042-&&-fertilization, exchange of chromosomal proteins-%%-GO:0007289-&&-spermatid nucleus differentiation-%%-GO:0007290-&&-spermatid nucleus elongation-%%-GO:0006337-&&-nucleosome disassembly-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0000012-&&-single strand break repair-%%-GO:0007286-&&-spermatid development-%%-GO:0006342-&&-chromatin silencing-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0019953-&&-sexual reproduction-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0000786-&&-nucleosome-%%-GO:0001673-&&-male germ cell nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003677-&&-DNA binding	G:9606:TNP1				TNP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNP1	0.3368896	0.2	6	5	FALSE	TNP1	TNP1	124.3333333	0	6	0	0.67194475	FALSE	0	TNP1	1588	0.2093873
788755	taxon:9606	2.96139909	6.80E-07	177007	1902	zinc finger protein 135	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0022604-&&-regulation of cell morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF135				ZNF135	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF135	0.33767823	0.06666667	6	5	FALSE	ZNF135	ZNF135	160.6666667	0	6	0	0.67310015	FALSE	0	ZNF135	2152	0.22824536
789066	taxon:9606	2.96313219	1.68E-06	176254	1902	HESX homeobox 1	gene	biological_process-&-1&-GO:0043584-&&-nose development-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007420-&&-brain development-%%-GO:0048853-&&-forebrain morphogenesis-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0047485-&&-protein N-terminus binding	G:9606:HESX1			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells	HESX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HESX1	0.33748073	0.06666667	6	5	FALSE	HESX1	HESX1	139.1666667	0	6	0	0.6728113	FALSE	0	HESX1	2714	0.20610119
789267	taxon:9606	3.01165905	8.20E-07	175874	1902	JMJD7-PLA2G4B readthrough	gene		G:9606:JMJD7-PLA2G4B			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa04726-&&-Serotonergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04730-&&-Long-term depression-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa04217-&&-Necroptosis	JMJD7-PLA2G4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JMJD7-PLA2G4B	0.3320429	0.26666667	6	5	FALSE	JMJD7-PLA2G4B	JMJD7-PLA2G4B	103.3333333	0	6	0	0.66472349	FALSE	0	JMJD7-PLA2G4B	1436	0.22637363
789270	taxon:9606	3.20844493	2.68E-06	175853	1902	beta-1,3-galactosyltransferase 2	gene	biological_process-&-1&-GO:0006486-&&-protein glycosylation-%%-GO:0009312-&&-oligosaccharide biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0047275-&&-glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity-%%-GO:0008499-&&-UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	G:9606:B3GALT2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00601-&&-Glycosphingolipid biosynthesis - lacto and neolacto series	B3GALT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B3GALT2	0.31167747	0	6	5	FALSE	B3GALT2	B3GALT2	32.33333333	0	6	0	0.63192584	FALSE	0	B3GALT2	1472	0.17904762
789361	taxon:9606	3.01449504	0	175666	1902	proprotein convertase subtilisin/kexin type 7	gene	biological_process-&-1&-GO:0016486-&&-peptide hormone processing-%%-GO:0016485-&&-protein processing|cellular_component-&-1&-GO:0030173-&&-integral component of Golgi membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0008233-&&-peptidase activity	G:9606:PCSK7				PCSK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCSK7	0.33173052	1	6	5	FALSE	PCSK7	PCSK7	170	0	5	0	0.66425083	FALSE	1	PCSK7	0	0.33464567
789402	taxon:9606	2.93760832	1.23E-06	175552	1902	neuronal regeneration related protein	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NREP				NREP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NREP	0.34041298	0	6	5	FALSE	NREP	NREP	144.6666667	0	6	0	0.67706528	FALSE	0	NREP	2266	0.19336025
789516	taxon:9606	3.02725697	2.26E-06	175294	1902	DExH-box helicase 34	gene	biological_process-&-1&-GO:0006396-&&-RNA processing-%%-GO:0000956-&&-nuclear-transcribed mRNA catabolic process-%%-GO:2000623-&&-negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0004004-&&-ATP-dependent RNA helicase activity	G:9606:DHX34				DHX34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DHX34	0.33033205	0	6	5	FALSE	DHX34	DHX34	78.16666667	0	6	0	0.66212384	FALSE	0	DHX34	1992	0.18373016
789533	taxon:9606	3.01890657	3.76E-05	175241	1902	C-X-C motif chemokine ligand 13	gene	biological_process-&-1&-GO:0002518-&&-lymphocyte chemotaxis across high endothelial venule-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0033625-&&-positive regulation of integrin activation-%%-GO:0048535-&&-lymph node development-%%-GO:0035768-&&-endothelial cell chemotaxis to fibroblast growth factor-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:2000545-&&-negative regulation of endothelial cell chemotaxis to fibroblast growth factor-%%-GO:0002544-&&-chronic inflammatory response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0033634-&&-positive regulation of cell-cell adhesion mediated by integrin-%%-GO:0006954-&&-inflammatory response-%%-GO:0035754-&&-B cell chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0035769-&&-B cell chemotaxis across high endothelial venule-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0002467-&&-germinal center formation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0002920-&&-regulation of humoral immune response-%%-GO:0010820-&&-positive regulation of T cell chemotaxis-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005623-&&-cell-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0017134-&&-fibroblast growth factor binding-%%-GO:0048018-&&-receptor agonist activity-%%-GO:0031735-&&-CCR10 chemokine receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0048248-&&-CXCR3 chemokine receptor binding-%%-GO:0008201-&&-heparin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0031724-&&-CXCR5 chemokine receptor binding	G:9606:CXCL13			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CXCL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL13	0.33124576	0.06666667	6	5	FALSE	CXCL13	CXCL13	73.16666667	0	6	0	0.66351557	FALSE	0	CXCL13	44148	0.17597087
789564	taxon:9606	2.86954467	9.00E-07	158785	1902	mex-3 RNA binding family member D	gene	biological_process-&-1&-GO:0010609-&&-mRNA localization resulting in posttranscriptional regulation of gene expression-%%-GO:0061157-&&-mRNA destabilization|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0017091-&&-AU-rich element binding	G:9606:MEX3D				MEX3D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEX3D	0.34848734	0.33333333	6	5	FALSE	MEX3D	MEX3D	204.1666667	0	6	0	0.68840922	FALSE	0	MEX3D	2180	0.19370651
789588	taxon:9606	2.72711517	2.70E-06	175122	1902	synaptic vesicle glycoprotein 2A	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0006836-&&-neurotransmitter transport|cellular_component-&-1&-GO:0030285-&&-integral component of synaptic vesicle membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0008021-&&-synaptic vesicle-%%-GO:0043195-&&-terminal bouton-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0022857-&&-transmembrane transporter activity-%%-GO:0004872-&&-receptor activity	G:9606:SV2A			KEGG-&-1&-hsa04512-&&-ECM-receptor interaction	SV2A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SV2A	0.36668785	0	6	4	FALSE	SV2A	SV2A	360.8333333	0	6	0	0.71214747	FALSE	0	SV2A	9110	0.19180881
789661	taxon:9606	2.87647708	1.35E-06	174949	1902	testis-specific kinase 2	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0048041-&&-focal adhesion assembly|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0016604-&&-nuclear body-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004712-&&-protein serine/threonine/tyrosine kinase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:TESK2				TESK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TESK2	0.34764748	0.06666667	6	4	FALSE	TESK2	TESK2	211.6666667	0	6	0	0.68725382	FALSE	0	TESK2	2950	0.20037987
789773	taxon:9606	2.89302032	1.12E-06	174718	1902	aminoadipate-semialdehyde synthase	gene	biological_process-&-1&-GO:0006554-&&-lysine catabolic process-%%-GO:0033512-&&-L-lysine catabolic process to acetyl-CoA via saccharopine-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0051262-&&-protein tetramerization|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0047131-&&-saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity-%%-GO:0047130-&&-saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	G:9606:AASS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00310-&&-Lysine degradation	AASS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AASS	0.34565951	0	6	4	FALSE	AASS	AASS	197.5	0	6	0	0.68449661	FALSE	0	AASS	2826	0.18985507
789834	taxon:9606	2.8854577	3.15E-06	174541	1902	Fas activated serine/threonine kinase	gene	biological_process-&-1&-GO:0043484-&&-regulation of RNA splicing-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003723-&&-RNA binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0033867-&&-Fas-activated serine/threonine kinase activity	G:9606:FASTK				FASTK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FASTK	0.34656547	0.06666667	6	5	FALSE	FASTK	FASTK	190.3333333	0	6	0	0.68575705	FALSE	0	FASTK	3878	0.18872305
789862	taxon:9606	2.96013865	2.09E-06	174489	1902	cyclin I	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0051726-&&-regulation of cell cycle	G:9606:CCNI				CCNI	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCNI	0.33782201	0	6	5	FALSE	CCNI	CCNI	110.6666667	0	6	0	0.67331023	FALSE	0	CCNI	2404	0.1855612
789909	taxon:9606	2.98550496	2.16E-06	174381	1902	NPR2-like, GATOR1 complex subunit	gene	biological_process-&-1&-GO:0034198-&&-cellular response to amino acid starvation-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:0010508-&&-positive regulation of autophagy-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:2000785-&&-regulation of autophagosome assembly-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0033673-&&-negative regulation of kinase activity-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005773-&&-vacuole-%%-GO:1990130-&&-Iml1 complex|molecular_function-&-1&-GO:0004672-&&-protein kinase activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:NPRL2			KEGG-&-1&-hsa04150-&&-mTOR signaling pathway	NPRL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPRL2	0.33495171	0.06666667	6	5	FALSE	NPRL2	NPRL2	114.5	0	6	0	0.66908251	FALSE	0	NPRL2	2260	0.20363745
790004	taxon:9606	3.01039861	1.64E-06	157758	1902	transmembrane protein 41B	gene	biological_process-&-1&-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMEM41B				TMEM41B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM41B	0.33218192	0.06666667	6	5	FALSE	TMEM41B	TMEM41B	168.1666667	0	6	0	0.66493356	FALSE	0	TMEM41B	4510	0.2518797
790020	taxon:9606	2.89160233	1.30E-06	174084	1902	transmembrane p24 trafficking protein 1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0015031-&&-protein transport-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0033116-&&-endoplasmic reticulum-Golgi intermediate compartment membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005793-&&-endoplasmic reticulum-Golgi intermediate compartment-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:TMED1				TMED1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMED1	0.34582902	0.2	6	4	FALSE	TMED1	TMED1	171.5	0	6	0	0.68473294	FALSE	0	TMED1	2288	0.19186264
790050	taxon:9606	2.77501182	2.40E-07	174000	1902	protein tyrosine phosphatase, receptor type T	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0007165-&&-signal transduction-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0007156-&&-homophilic cell adhesion via plasma membrane adhesion molecules-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0006470-&&-protein dephosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0045294-&&-alpha-catenin binding-%%-GO:0045296-&&-cadherin binding-%%-GO:0005515-&&-protein binding-%%-GO:0008013-&&-beta-catenin binding-%%-GO:0045295-&&-gamma-catenin binding-%%-GO:0070097-&&-delta-catenin binding	G:9606:PTPRT				PTPRT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTPRT	0.36035883	0.33333333	6	5	FALSE	PTPRT	PTPRT	477.25	0	5	0	0.7041647	FALSE	1	PTPRT	1496	0.29924718
790156	taxon:9606	2.97605168	8.00E-08	173745	1902	HMG-box containing 3	gene	biological_process-&-1&-GO:0008150-&&-biological_process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0016301-&&-kinase activity	G:9606:HMGXB3				HMGXB3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGXB3	0.33601567	0.33333333	6	5	FALSE	HMGXB3	HMGXB3	174.8333333	0	6	0	0.67065805	FALSE	0	HMGXB3	566	0.30780516
790196	taxon:9606	2.96013865	4.60E-07	173668	1902	Rho GTPase activating protein 26	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0007165-&&-signal transduction-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005829-&&-cytosol-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005925-&&-focal adhesion|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding	G:9606:ARHGAP26				ARHGAP26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP26	0.33782201	0.2	6	5	FALSE	ARHGAP26	ARHGAP26	120.5	0	6	0	0.67331023	FALSE	0	ARHGAP26	1032	0.19662309
790304	taxon:9606	2.95714511	1.40E-06	173378	1902	sulfotransferase family 4A member 1	gene	biological_process-&-1&-GO:0050427-&&-3'-phosphoadenosine 5'-phosphosulfate metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008146-&&-sulfotransferase activity-%%-GO:0004062-&&-aryl sulfotransferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0042802-&&-identical protein binding	G:9606:SULT4A1				SULT4A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SULT4A1	0.33816399	0	6	5	FALSE	SULT4A1	SULT4A1	170	0	5	0	0.67380915	FALSE	1	SULT4A1	1312	0.27258065
790324	taxon:9606	2.9153931	4.63E-06	173312	1902	myosin VIIA and Rab interacting protein	gene	biological_process-&-1&-GO:0032024-&&-positive regulation of insulin secretion-%%-GO:0006886-&&-intracellular protein transport|cellular_component-&-1&-GO:0030133-&&-transport vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0001750-&&-photoreceptor outer segment-%%-GO:0045202-&&-synapse-%%-GO:0031045-&&-dense core granule-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0000145-&&-exocyst-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0017022-&&-myosin binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0051018-&&-protein kinase A binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:MYRIP				MYRIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYRIP	0.34300692	0.2	6	5	FALSE	MYRIP	MYRIP	197.3333333	0	6	0	0.68076782	FALSE	0	MYRIP	4654	0.23321485
790362	taxon:9606	2.96265952	5.40E-07	173216	1902	lysine acetyltransferase 6B	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0016573-&&-histone acetylation-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043966-&&-histone H3 acetylation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006334-&&-nucleosome assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070776-&&-MOZ/MORF histone acetyltransferase complex-%%-GO:0000786-&&-nucleosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0032403-&&-protein complex binding-%%-GO:0016407-&&-acetyltransferase activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0004402-&&-histone acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:KAT6B				KAT6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KAT6B	0.33753457	0	6	5	FALSE	KAT6B	KAT6B	139.1666667	0	6	0	0.67289008	FALSE	0	KAT6B	1422	0.2022938
790443	taxon:9606	2.90278872	5.90E-07	172938	1902	ribosomal protein S6 kinase C1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005769-&&-early endosome-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0035091-&&-phosphatidylinositol binding-%%-GO:0005515-&&-protein binding	G:9606:RPS6KC1				RPS6KC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KC1	0.34449631	0.16666667	6	5	FALSE	RPS6KC1	RPS6KC1	246.5	0	5	0	0.68286855	FALSE	1	RPS6KC1	1178	0.27640449
790549	taxon:9606	3.00441153	8.60E-07	172410	1902	NFKB inhibitor interacting Ras like 2	gene	biological_process-&-1&-GO:0007249-&&-I-kappaB kinase/NF-kappaB signaling-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0005525-&&-GTP binding	G:9606:NKIRAS2				NKIRAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKIRAS2	0.33284388	0.13333333	6	5	FALSE	NKIRAS2	NKIRAS2	132.6666667	0	6	0	0.66593141	FALSE	0	NKIRAS2	1540	0.28096249
790629	taxon:9606	3.09232708	1.65E-06	171708	1902	hippocalcin like 4	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0007165-&&-signal transduction|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005246-&&-calcium channel regulator activity	G:9606:HPCAL4				HPCAL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPCAL4	0.32338106	0	6	5	FALSE	HPCAL4	HPCAL4	63	0	6	0	0.65127882	FALSE	0	HPCAL4	1864	0.21088435
790644	taxon:9606	2.94217741	4.28E-06	171680	1902	myotubularin related protein 12	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0050790-&&-regulation of catalytic activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0019208-&&-phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:MTMR12				MTMR12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTMR12	0.33988433	0.13333333	6	5	FALSE	MTMR12	MTMR12	131	0	6	0	0.67630377	FALSE	0	MTMR12	4842	0.19051095
790724	taxon:9606	3.05766504	8.80E-07	171386	1902	TNNI3 interacting kinase	gene	biological_process-&-1&-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0086069-&&-bundle of His cell to Purkinje myocyte communication-%%-GO:0006468-&&-protein phosphorylation-%%-GO:1903779-&&-regulation of cardiac conduction|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008022-&&-protein C-terminus binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0031013-&&-troponin I binding	G:9606:TNNI3K				TNNI3K	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNNI3K	0.32704694	0.06666667	6	5	FALSE	TNNI3K	TNNI3K	54.5	0	6	0	0.65705583	FALSE	0	TNNI3K	1044	0.1922619
790773	taxon:9606	2.78147156	8.25E-06	171261	1902	shisa family member 5	gene	biological_process-&-1&-GO:0042771-&&-intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding	G:9606:SHISA5			KEGG-&-1&-hsa04115-&&-p53 signaling pathway	SHISA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHISA5	0.35952192	0.26666667	6	4	FALSE	SHISA5	SHISA5	336.6666667	0	6	0	0.70308807	FALSE	0	SHISA5	7386	0.21433121
790848	taxon:9606	2.83614306	6.89E-06	170931	1902	ybeY metallopeptidase (putative)	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0006364-&&-rRNA processing|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:YBEY				YBEY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBEY	0.35259152	0.13333333	6	5	FALSE	YBEY	YBEY	233.3333333	0	6	0	0.69397616	FALSE	0	YBEY	6044	0.18626667
790899	taxon:9606	2.95556956	3.81E-06	170737	1902	GSK3B interacting protein	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm	G:9606:GSKIP				GSKIP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSKIP	0.33834426	0.06666667	6	5	FALSE	GSKIP	GSKIP	122.3333333	0	6	0	0.67407174	FALSE	0	GSKIP	3930	0.18833849
790929	taxon:9606	3.03938869	4.01E-06	170681	1902	dynein cytoplasmic 2 light intermediate chain 1	gene	biological_process-&-1&-GO:0035735-&&-intraciliary transport involved in cilium assembly-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0060271-&&-cilium assembly|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0031514-&&-motile cilium-%%-GO:0036064-&&-ciliary basal body-%%-GO:0030990-&&-intraciliary transport particle-%%-GO:0005881-&&-cytoplasmic microtubule-%%-GO:0005930-&&-axoneme-%%-GO:0005813-&&-centrosome-%%-GO:0035869-&&-ciliary transition zone-%%-GO:0005868-&&-cytoplasmic dynein complex-%%-GO:0045177-&&-apical part of cell-%%-GO:0005737-&&-cytoplasm-%%-GO:0097542-&&-ciliary tip|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0045504-&&-dynein heavy chain binding-%%-GO:0008569-&&-ATP-dependent microtubule motor activity, minus-end-directed	G:9606:DYNC2LI1			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption	DYNC2LI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DYNC2LI1	0.32901353	0	6	5	FALSE	DYNC2LI1	DYNC2LI1	92	0	6	0	0.66010189	FALSE	0	DYNC2LI1	3638	0.1743295
790942	taxon:9606	3.06774854	1.88E-06	170648	1902	ornithine decarboxylase antizyme 3	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006595-&&-polyamine metabolic process-%%-GO:0006596-&&-polyamine biosynthetic process-%%-GO:0015847-&&-putrescine transport-%%-GO:1902268-&&-negative regulation of polyamine transmembrane transport-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0072562-&&-blood microparticle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0015489-&&-putrescine transmembrane transporter activity-%%-GO:0008073-&&-ornithine decarboxylase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:OAZ3				OAZ3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OAZ3	0.32597196	0.13333333	6	5	FALSE	OAZ3	OAZ3	66.66666667	0	6	0	0.65537524	FALSE	0	OAZ3	2058	0.1837963
791054	taxon:9606	2.92642193	1.26E-06	170215	1902	stabilin 2	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0001525-&&-angiogenesis-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006897-&&-endocytosis-%%-GO:0030193-&&-regulation of blood coagulation-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0030214-&&-hyaluronan catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0030666-&&-endocytic vesicle membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0005041-&&-low-density lipoprotein receptor activity-%%-GO:0005540-&&-hyaluronic acid binding	G:9606:STAB2				STAB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAB2	0.34171422	0.4	6	5	FALSE	STAB2	STAB2	193.6666667	0	6	0	0.67892968	FALSE	0	STAB2	1562	0.24196913
791065	taxon:9606	2.98455963	2.20E-06	170174	1902	chromosome 1 open reading frame 123	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:C1orf123				C1orf123	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1orf123	0.3350578	0.06666667	6	5	FALSE	C1orf123	C1orf123	99	0	6	0	0.66924006	FALSE	0	C1orf123	2100	0.18483709
791101	taxon:9606	2.94816449	5.39E-06	170049	1902	phosphatidylinositol 4-kinase type 2 beta	gene	biological_process-&-1&-GO:0007032-&&-endosome organization-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0007030-&&-Golgi organization-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005765-&&-lysosomal membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004430-&&-1-phosphatidylinositol 4-kinase activity	G:9606:PI4K2B			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PI4K2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PI4K2B	0.3391941	0.06666667	6	4	FALSE	PI4K2B	PI4K2B	117.6666667	0	6	0	0.67530592	FALSE	0	PI4K2B	4276	0.17862595
791222	taxon:9606	3.11139121	3.75E-05	169686	1902	presenilin enhancer gamma-secretase subunit	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0034205-&&-beta-amyloid formation-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0042987-&&-amyloid precursor protein catabolic process-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0016485-&&-protein processing-%%-GO:0042982-&&-amyloid precursor protein metabolic process-%%-GO:0006509-&&-membrane protein ectodomain proteolysis-%%-GO:0007220-&&-Notch receptor processing-%%-GO:0031293-&&-membrane protein intracellular domain proteolysis-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0070765-&&-gamma-secretase complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PSENEN			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05010-&&-Alzheimer disease	PSENEN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSENEN	0.32139964	0.33333333	6	5	FALSE	PSENEN	PSENEN	65.33333333	0	6	0	0.64810147	FALSE	0	PSENEN	34482	0.19287834
791284	taxon:9606	2.93934142	6.60E-07	169354	1902	phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0030833-&&-regulation of actin filament polymerization-%%-GO:0042119-&&-neutrophil activation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0032007-&&-negative regulation of TOR signaling-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0006801-&&-superoxide metabolic process-%%-GO:0050773-&&-regulation of dendrite development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading-%%-GO:0030217-&&-T cell differentiation-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0035023-&&-regulation of Rho protein signal transduction-%%-GO:0043065-&&-positive regulation of apoptotic process|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0043198-&&-dendritic shaft-%%-GO:0005829-&&-cytosol-%%-GO:0030426-&&-growth cone|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0005089-&&-Rho guanyl-nucleotide exchange factor activity-%%-GO:0030676-&&-Rac guanyl-nucleotide exchange factor activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity	G:9606:PREX1			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection	PREX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PREX1	0.34021226	0.46666667	6	5	FALSE	PREX1	PREX1	140.5	0	6	0	0.67677643	FALSE	0	PREX1	932	0.21359716
791290	taxon:9606	2.90404916	1.06E-06	169316	1902	kelch like family member 1	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination-%%-GO:0007628-&&-adult walking behavior-%%-GO:0021680-&&-cerebellar Purkinje cell layer development-%%-GO:0030036-&&-actin cytoskeleton organization-%%-GO:0016358-&&-dendrite development|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0003779-&&-actin binding	G:9606:KLHL1				KLHL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL1	0.34434679	0.26666667	6	5	FALSE	KLHL1	KLHL1	183.8333333	0	6	0	0.68265847	FALSE	0	KLHL1	2322	0.21091954
791373	taxon:9606	2.85914605	2.75E-06	168916	1902	zinc finger FYVE-type containing 28	gene	biological_process-&-1&-GO:0042059-&&-negative regulation of epidermal growth factor receptor signaling pathway-%%-GO:0007175-&&-negative regulation of epidermal growth factor-activated receptor activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0031901-&&-early endosome membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0032266-&&-phosphatidylinositol-3-phosphate binding-%%-GO:0005515-&&-protein binding	G:9606:ZFYVE28				ZFYVE28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFYVE28	0.34975478	0.33333333	6	4	FALSE	ZFYVE28	ZFYVE28	206.8333333	0	6	0	0.69014232	FALSE	0	ZFYVE28	3874	0.1833777
791386	taxon:9606	2.77012762	6.90E-07	168845	1902	lymphocyte antigen 6 family member G5B	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:LY6G5B				LY6G5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LY6G5B	0.3609942	0.06666667	6	4	FALSE	LY6G5B	LY6G5B	399.8333333	0	6	0	0.70497873	FALSE	0	LY6G5B	5170	0.24670375
791387	taxon:9606	2.7562628	2.69E-06	168844	1902	prune exopolyphosphatase 1	gene	cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004427-&&-inorganic diphosphatase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:PRUNE1			KEGG-&-1&-hsa00230-&&-Purine metabolism	PRUNE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRUNE1	0.36281011	0	6	4	FALSE	PRUNE1	PRUNE1	465.75	0	5	0	0.70728953	FALSE	1	PRUNE1	5498	0.26802191
791396	taxon:9606	3.26138333	2.06E-06	168809	1902	angiotensin I converting enzyme 2	gene	biological_process-&-1&-GO:1903779-&&-regulation of cardiac conduction-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0002005-&&-angiotensin catabolic process in blood-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:0001817-&&-regulation of cytokine production-%%-GO:0046813-&&-receptor-mediated virion attachment to host cell-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:1903598-&&-positive regulation of gap junction assembly-%%-GO:0003081-&&-regulation of systemic arterial blood pressure by renin-angiotensin-%%-GO:0032800-&&-receptor biosynthetic process-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0060452-&&-positive regulation of cardiac muscle contraction-%%-GO:0003051-&&-angiotensin-mediated drinking behavior-%%-GO:0015827-&&-tryptophan transport-%%-GO:0097746-&&-regulation of blood vessel diameter-%%-GO:0002003-&&-angiotensin maturation|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0004175-&&-endopeptidase activity-%%-GO:0004180-&&-carboxypeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008237-&&-metallopeptidase activity-%%-GO:0008241-&&-peptidyl-dipeptidase activity-%%-GO:0001618-&&-virus receptor activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0001948-&&-glycoprotein binding-%%-GO:0004181-&&-metallocarboxypeptidase activity	G:9606:ACE2	ACE2	TRUE	KEGG-&-1&-hsa04614-&&-Renin-angiotensin system-%%-hsa04974-&&-Protein digestion and absorption	ACE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACE2	0.30661836	0	6	5	FALSE	ACE2	ACE2	23.75	0	5	0	0.62310278	FALSE	1	ACE2	1840	0.25277778
791440	taxon:9606	2.80226879	1.67E-06	168628	1902	family with sequence similarity 173 member A	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:FAM173A				FAM173A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM173A	0.35685371	0.13333333	6	4	FALSE	FAM173A	FAM173A	274.1666667	0	6	0	0.69962187	FALSE	0	FAM173A	3728	0.19559524
791468	taxon:9606	2.96770128	1.31E-06	168512	1902	PHD finger protein 23	gene	biological_process-&-1&-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1901097-&&-negative regulation of autophagosome maturation-%%-GO:1902902-&&-negative regulation of autophagosome assembly-%%-GO:0006914-&&-autophagy|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:PHF23				PHF23	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PHF23	0.33696114	0	6	4	FALSE	PHF23	PHF23	97.5	0	6	0	0.67204979	FALSE	0	PHF23	1800	0.18241966
791488	taxon:9606	2.97290058	4.11E-06	168421	1902	centromere protein K	gene	biological_process-&-1&-GO:0034080-&&-CENP-A containing nucleosome assembly-%%-GO:0007062-&&-sister chromatid cohesion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000777-&&-condensed chromosome kinetochore|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CENPK				CENPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CENPK	0.33637183	0	6	5	FALSE	CENPK	CENPK	109.3333333	0	6	0	0.67118324	FALSE	0	CENPK	3498	0.17416935
791523	taxon:9606	2.94832204	1.52E-06	168256	1902	MORC family CW-type zinc finger 4	gene	cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:MORC4				MORC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MORC4	0.33917597	0	6	5	FALSE	MORC4	MORC4	122	0	6	0	0.67527966	FALSE	0	MORC4	2344	0.18032787
791559	taxon:9606	3.08586734	1.57E-05	168047	1902	adiponectin receptor 2	gene	biological_process-&-1&-GO:0019395-&&-fatty acid oxidation-%%-GO:0033211-&&-adiponectin-activated signaling pathway-%%-GO:0007507-&&-heart development-%%-GO:0061042-&&-vascular wound healing-%%-GO:0007565-&&-female pregnancy-%%-GO:0007584-&&-response to nutrient-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0042304-&&-regulation of fatty acid biosynthetic process-%%-GO:0009755-&&-hormone-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031226-&&-intrinsic component of plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0097003-&&-adipokinetic hormone receptor activity-%%-GO:0055100-&&-adiponectin binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0042802-&&-identical protein binding	G:9606:ADIPOR2	ADIPOR2	TRUE	KEGG-&-1&-hsa04932-&&-Non-alcoholic fatty liver disease (NAFLD)-%%-hsa04152-&&-AMPK signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa04211-&&-Longevity regulating pathway	ADIPOR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADIPOR2	0.324058	0	6	5	FALSE	ADIPOR2	ADIPOR2	87.33333333	0	6	0	0.65235544	FALSE	0	ADIPOR2	12352	0.20077519
791609	taxon:9606	2.92925792	1.88E-06	167828	1902	MICAL like 2	gene	biological_process-&-1&-GO:0070830-&&-bicellular tight junction assembly-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0032456-&&-endocytic recycling-%%-GO:0031175-&&-neuron projection development|cellular_component-&-1&-GO:0055037-&&-recycling endosome-%%-GO:0032432-&&-actin filament bundle-%%-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0001725-&&-stress fiber-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005829-&&-cytosol-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0031005-&&-filamin binding-%%-GO:0042805-&&-actinin binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:MICALL2			KEGG-&-1&-hsa04530-&&-Tight junction	MICALL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MICALL2	0.34138339	0.13333333	6	4	FALSE	MICALL2	MICALL2	143.5	0	6	0	0.67845701	FALSE	0	MICALL2	2572	0.18214589
791629	taxon:9606	2.78194423	5.70E-07	167739	1902	microtubule associated protein 9	gene	biological_process-&-1&-GO:0000910-&&-cytokinesis-%%-GO:0007088-&&-regulation of mitotic nuclear division-%%-GO:0090307-&&-mitotic spindle assembly|cellular_component-&-1&-GO:0000235-&&-astral microtubule-%%-GO:1990023-&&-mitotic spindle midzone	G:9606:MAP9				MAP9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP9	0.35946084	0.33333333	6	4	FALSE	MAP9	MAP9	324.5	0	6	0	0.7030093	FALSE	0	MAP9	2166	0.20844045
791664	taxon:9606	3.00645974	6.60E-07	167537	1902	ADAM metallopeptidase with thrombospondin type 1 motif 10	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0001527-&&-microfibril-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:ADAMTS10				ADAMTS10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADAMTS10	0.33261713	0.13333333	6	5	FALSE	ADAMTS10	ADAMTS10	160.8333333	0	6	0	0.66559004	FALSE	0	ADAMTS10	1656	0.31165049
791665	taxon:9606	2.99070427	1.20E-06	167538	1902	toll like receptor 10	gene	biological_process-&-1&-GO:0034166-&&-toll-like receptor 10 signaling pathway-%%-GO:0002755-&&-MyD88-dependent toll-like receptor signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0006955-&&-immune response-%%-GO:0002224-&&-toll-like receptor signaling pathway-%%-GO:0050707-&&-regulation of cytokine secretion-%%-GO:0006954-&&-inflammatory response-%%-GO:0050729-&&-positive regulation of inflammatory response|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:TLR10				TLR10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TLR10	0.3343694	0	6	4	FALSE	TLR10	TLR10	87.66666667	0	6	0	0.66821596	FALSE	0	TLR10	1580	0.18018018
791699	taxon:9606	3.01165905	8.20E-07	150945	1902	phospholipase A2 group IVB	gene	biological_process-&-1&-GO:0036152-&&-phosphatidylethanolamine acyl-chain remodeling-%%-GO:0006954-&&-inflammatory response-%%-GO:0007567-&&-parturition-%%-GO:0046475-&&-glycerophospholipid catabolic process-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0036151-&&-phosphatidylcholine acyl-chain remodeling-%%-GO:0036498-&&-IRE1-mediated unfolded protein response-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0036148-&&-phosphatidylglycerol acyl-chain remodeling-%%-GO:0036150-&&-phosphatidylserine acyl-chain remodeling-%%-GO:0019369-&&-arachidonic acid metabolic process|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008970-&&-phosphatidylcholine 1-acylhydrolase activity-%%-GO:0004623-&&-phospholipase A2 activity-%%-GO:0005544-&&-calcium-dependent phospholipid binding-%%-GO:0004622-&&-lysophospholipase activity-%%-GO:0047498-&&-calcium-dependent phospholipase A2 activity-%%-GO:0005509-&&-calcium ion binding	G:9606:PLA2G4B			KEGG-&-1&-hsa05231-&&-Choline metabolism in cancer-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04370-&&-VEGF signaling pathway-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04730-&&-Long-term depression-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04666-&&-Fc gamma R-mediated phagocytosis-%%-hsa04611-&&-Platelet activation-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04217-&&-Necroptosis	PLA2G4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLA2G4B	0.3320429	0.26666667	6	5	FALSE	PLA2G4B	PLA2G4B	103.3333333	0	6	0	0.66472349	FALSE	0	PLA2G4B	1436	0.22637363
791703	taxon:9606	3.13061289	3.01E-06	167305	1902	sphingolipid transporter 1 (putative)	gene	biological_process-&-1&-GO:0040011-&&-locomotion-%%-GO:0055085-&&-transmembrane transport-%%-GO:0003376-&&-sphingosine-1-phosphate signaling pathway-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0046624-&&-sphingolipid transporter activity-%%-GO:0005515-&&-protein binding	G:9606:SPNS1				SPNS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPNS1	0.31942627	0.2	6	5	FALSE	SPNS1	SPNS1	53.83333333	0	6	0	0.64489785	FALSE	0	SPNS1	2472	0.2124834
791711	taxon:9606	3.02457854	2.17E-06	167267	1902	ankyrin repeat domain 27	gene	biological_process-&-1&-GO:0048812-&&-neuron projection morphogenesis-%%-GO:1990126-&&-retrograde transport, endosome to plasma membrane-%%-GO:0061024-&&-membrane organization-%%-GO:0015031-&&-protein transport-%%-GO:0045022-&&-early endosome to late endosome transport-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0035544-&&-negative regulation of SNARE complex assembly-%%-GO:0035646-&&-endosome to melanosome transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0005764-&&-lysosome-%%-GO:0005770-&&-late endosome-%%-GO:0016020-&&-membrane-%%-GO:0097422-&&-tubular endosome-%%-GO:0042470-&&-melanosome-%%-GO:0005829-&&-cytosol-%%-GO:0005769-&&-early endosome-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0017137-&&-Rab GTPase binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0000149-&&-SNARE binding-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity	G:9606:ANKRD27				ANKRD27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD27	0.33062458	0.06666667	6	5	FALSE	ANKRD27	ANKRD27	71.33333333	0	6	0	0.66257024	FALSE	0	ANKRD27	1936	0.17935702
791733	taxon:9606	2.75437214	4.16E-06	167129	1902	chromosome 18 open reading frame 21	gene		G:9606:C18orf21				C18orf21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C18orf21	0.36305915	0.06666667	6	5	FALSE	C18orf21	C18orf21	333.1666667	0	6	0	0.70760464	FALSE	0	C18orf21	6178	0.19662921
791834	taxon:9606	3.10965811	2.06E-06	166619	1902	zinc finger protein 503	gene	biological_process-&-1&-GO:0061351-&&-neural precursor cell proliferation-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0070315-&&-G1 to G0 transition involved in cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF503				ZNF503	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF503	0.32157876	0	6	5	FALSE	ZNF503	ZNF503	56.66666667	0	6	0	0.64839032	FALSE	0	ZNF503	1984	0.17395833
791924	taxon:9606	2.94784938	6.00E-07	182870	1902	aldehyde dehydrogenase 1 family member A1	gene	biological_process-&-1&-GO:0042572-&&-retinol metabolic process-%%-GO:0061624-&&-fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0006081-&&-cellular aldehyde metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006069-&&-ethanol oxidation-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004029-&&-aldehyde dehydrogenase (NAD) activity-%%-GO:0001758-&&-retinal dehydrogenase activity-%%-GO:0005497-&&-androgen binding-%%-GO:0018479-&&-benzaldehyde dehydrogenase (NAD+) activity-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0000166-&&-nucleotide binding	G:9606:ALDH1A1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00830-&&-Retinol metabolism	ALDH1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALDH1A1	0.33923036	0	6	5	FALSE	ALDH1A1	ALDH1A1	189.25	0	5	0	0.67535844	FALSE	1	ALDH1A1	1260	0.26588983
791952	taxon:9606	2.84055459	4.62E-06	182815	1902	angiogenin	gene	biological_process-&-1&-GO:0090501-&&-RNA phosphodiester bond hydrolysis-%%-GO:0030041-&&-actin filament polymerization-%%-GO:0017148-&&-negative regulation of translation-%%-GO:0001525-&&-angiogenesis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0006651-&&-diacylglycerol biosynthetic process-%%-GO:0009725-&&-response to hormone-%%-GO:0007154-&&-cell communication-%%-GO:0034332-&&-adherens junction organization-%%-GO:0032431-&&-activation of phospholipase A2 activity-%%-GO:0009303-&&-rRNA transcription-%%-GO:0001878-&&-response to yeast-%%-GO:0048662-&&-negative regulation of smooth muscle cell proliferation-%%-GO:0019732-&&-antifungal humoral response-%%-GO:0042592-&&-homeostatic process-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0045087-&&-innate immune response-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0001556-&&-oocyte maturation-%%-GO:0016477-&&-cell migration-%%-GO:0001890-&&-placenta development-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0032148-&&-activation of protein kinase B activity|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005605-&&-basal lamina-%%-GO:0005730-&&-nucleolus-%%-GO:0030426-&&-growth cone-%%-GO:0032311-&&-angiogenin-PRI complex-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0004519-&&-endonuclease activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0005507-&&-copper ion binding-%%-GO:0004540-&&-ribonuclease activity-%%-GO:0019843-&&-rRNA binding-%%-GO:0008201-&&-heparin binding-%%-GO:0003677-&&-DNA binding-%%-GO:0042277-&&-peptide binding-%%-GO:0003779-&&-actin binding	G:9606:ANG				ANG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANG	0.35204393	0.06666667	6	4	FALSE	ANG	ANG	248.3333333	0	6	0	0.6932409	FALSE	0	ANG	5868	0.20201196
791974	taxon:9606	2.78525288	5.69E-06	166399	1902	thymic stromal lymphopoietin	gene	cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005125-&&-cytokine activity	G:9606:TSLP			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	TSLP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSLP	0.35903383	0.26666667	6	5	FALSE	TSLP	TSLP	290	0	6	0	0.70245785	FALSE	0	TSLP	7170	0.19156202
792025	taxon:9606	3.13565464	2.79E-06	182716	1902	biliverdin reductase B	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0042167-&&-heme catabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043195-&&-terminal bouton|molecular_function-&-1&-GO:0004074-&&-biliverdin reductase activity-%%-GO:0042602-&&-riboflavin reductase (NADPH) activity	G:9606:BLVRB			KEGG-&-1&-hsa00740-&&-Riboflavin metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism	BLVRB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLVRB	0.31891267	0	6	5	FALSE	BLVRB	BLVRB	48	0	6	0	0.64405756	FALSE	0	BLVRB	2564	0.16967509
792053	taxon:9606	2.98314164	7.00E-07	166297	1902	splA/ryanodine receptor domain and SOCS box containing 4	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPSB4				SPSB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPSB4	0.33521707	0.4	6	5	FALSE	SPSB4	SPSB4	135.5	0	6	0	0.66947639	FALSE	0	SPSB4	1816	0.20636132
792059	taxon:9606	2.84433591	2.86E-06	182679	1902	biotinidase	gene	biological_process-&-1&-GO:0007417-&&-central nervous system development-%%-GO:0006768-&&-biotin metabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0047708-&&-biotinidase activity-%%-GO:0016810-&&-hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	G:9606:BTD			KEGG-&-1&-hsa00780-&&-Biotin metabolism-%%-hsa04977-&&-Vitamin digestion and absorption-%%-hsa01100-&&-Metabolic pathways	BTD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTD	0.35157592	0.06666667	6	4	FALSE	BTD	BTD	230.6666667	0	6	0	0.69261068	FALSE	0	BTD	5622	0.19591141
792084	taxon:9606	3.05230818	4.35E-06	182646	1902	chymase 1	gene	biological_process-&-1&-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0002003-&&-angiotensin maturation-%%-GO:0016485-&&-protein processing-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0030901-&&-midbrain development-%%-GO:0050720-&&-interleukin-1 beta biosynthetic process|cellular_component-&-1&-GO:0031012-&&-extracellular matrix-%%-GO:0005623-&&-cell-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0042277-&&-peptide binding-%%-GO:0008236-&&-serine-type peptidase activity	G:9606:CMA1			KEGG-&-1&-hsa04614-&&-Renin-angiotensin system	CMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMA1	0.32762092	0.13333333	6	5	FALSE	CMA1	CMA1	61	0	6	0	0.65794864	FALSE	0	CMA1	4112	0.17382999
792097	taxon:9606	3.10855522	1.39E-06	182614	1902	cannabinoid receptor 1	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0035094-&&-response to nicotine-%%-GO:0060405-&&-regulation of penile erection-%%-GO:0033004-&&-negative regulation of mast cell activation-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0007413-&&-axonal fasciculation-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0099553-&&-trans-synaptic signaling by endocannabinoid, modulating synaptic transmission-%%-GO:0042220-&&-response to cocaine-%%-GO:0032228-&&-regulation of synaptic transmission, GABAergic-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0043278-&&-response to morphine-%%-GO:0007568-&&-aging-%%-GO:0007613-&&-memory-%%-GO:0038171-&&-cannabinoid signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0002866-&&-positive regulation of acute inflammatory response to antigenic stimulus-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051001-&&-negative regulation of nitric-oxide synthase activity-%%-GO:0007283-&&-spermatogenesis-%%-GO:0007584-&&-response to nutrient-%%-GO:0031999-&&-negative regulation of fatty acid beta-oxidation-%%-GO:0033602-&&-negative regulation of dopamine secretion-%%-GO:0060135-&&-maternal process involved in female pregnancy-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0019233-&&-sensory perception of pain-%%-GO:0060259-&&-regulation of feeding behavior-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0031622-&&-positive regulation of fever generation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0045759-&&-negative regulation of action potential|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030426-&&-growth cone-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0004949-&&-cannabinoid receptor activity	G:9606:CNR1	CNR1	TRUE	KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04714-&&-Thermogenesis-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	CNR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNR1	0.32169285	0.26666667	6	5	FALSE	CNR1	CNR1	62	0	6	0	0.64857413	FALSE	0	CNR1	1380	0.21191294
792159	taxon:9606	3.03450449	1.38E-05	182501	1902	adenylate cyclase 3	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0007338-&&-single fertilization-%%-GO:0007608-&&-sensory perception of smell-%%-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0006171-&&-cAMP biosynthetic process-%%-GO:0007165-&&-signal transduction-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0007190-&&-activation of adenylate cyclase activity-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0008355-&&-olfactory learning-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:1904322-&&-cellular response to forskolin-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007340-&&-acrosome reaction-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0034199-&&-activation of protein kinase A activity|cellular_component-&-1&-GO:0005929-&&-cilium-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0005737-&&-cytoplasm-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004016-&&-adenylate cyclase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004383-&&-guanylate cyclase activity	G:9606:ADCY3			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa04740-&&-Olfactory transduction-%%-hsa04914-&&-Progesterone-mediated oocyte maturation-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05200-&&-Pathways in cancer-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04927-&&-Cortisol synthesis and secretion-%%-hsa04976-&&-Bile secretion-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04934-&&-Cushing syndrome-%%-hsa04211-&&-Longevity regulating pathway-%%-hsa04540-&&-Gap junction-%%-hsa04114-&&-Oocyte meiosis-%%-hsa04923-&&-Regulation of lipolysis in adipocytes-%%-hsa04713-&&-Circadian entrainment-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa04928-&&-Parathyroid hormone synthesis, secretion and action-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa04912-&&-GnRH signaling pathway-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04714-&&-Thermogenesis-%%-hsa05032-&&-Morphine addiction-%%-hsa04724-&&-Glutamatergic synapse-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa05414-&&-Dilated cardiomyopathy (DCM)-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04213-&&-Longevity regulating pathway - multiple species-%%-hsa04911-&&-Insulin secretion-%%-hsa04970-&&-Salivary secretion	ADCY3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADCY3	0.32954309	0	6	4	FALSE	ADCY3	ADCY3	84.83333333	0	6	0	0.66091592	FALSE	0	ADCY3	11292	0.17761299
792226	taxon:9606	3.03198361	2.39E-06	166002	1902	myeloid associated differentiation marker	gene	biological_process-&-1&-GO:0045217-&&-cell-cell junction maintenance-%%-GO:0090038-&&-negative regulation of protein kinase C signaling-%%-GO:0072661-&&-protein targeting to plasma membrane-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0030837-&&-negative regulation of actin filament polymerization-%%-GO:0031579-&&-membrane raft organization-%%-GO:0010810-&&-regulation of cell-substrate adhesion-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0061028-&&-establishment of endothelial barrier-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0030864-&&-cortical actin cytoskeleton-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045121-&&-membrane raft-%%-GO:0001726-&&-ruffle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:MYADM				MYADM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYADM	0.32981709	0	6	5	FALSE	MYADM	MYADM	100.1666667	0	6	0	0.66133606	FALSE	0	MYADM	4016	0.18030303
792309	taxon:9606	2.9056247	9.30E-07	182244	1902	centrin 1	gene	biological_process-&-1&-GO:0051301-&&-cell division-%%-GO:0007067-&&-mitotic nuclear division-%%-GO:0034605-&&-cellular response to heat|cellular_component-&-1&-GO:0005813-&&-centrosome-%%-GO:0005814-&&-centriole-%%-GO:0000922-&&-spindle pole-%%-GO:0032391-&&-photoreceptor connecting cilium|molecular_function-&-1&-GO:0031683-&&-G-protein beta/gamma-subunit complex binding-%%-GO:0008017-&&-microtubule binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0032795-&&-heterotrimeric G-protein binding	G:9606:CETN1				CETN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CETN1	0.34416007	0.2	6	5	FALSE	CETN1	CETN1	173.3333333	0	6	0	0.68239588	FALSE	0	CETN1	1926	0.19611174
792369	taxon:9606	2.98392942	8.40E-07	165759	1902	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	gene	biological_process-&-1&-GO:0042177-&&-negative regulation of protein catabolic process-%%-GO:0015031-&&-protein transport-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005730-&&-nucleolus-%%-GO:0016020-&&-membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGAP2			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04068-&&-FoxO signaling pathway	AGAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGAP2	0.33512857	0.2	6	5	FALSE	AGAP2	AGAP2	125.3333333	0	6	0	0.6693451	FALSE	0	AGAP2	1552	0.21086712
792392	taxon:9606	2.89081456	2.00E-08	165716	1902	tripartite motif containing 6	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0070206-&&-protein trimerization-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway-%%-GO:0098586-&&-cellular response to virus-%%-GO:0010800-&&-positive regulation of peptidyl-threonine phosphorylation-%%-GO:0010994-&&-free ubiquitin chain polymerization-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0035458-&&-cellular response to interferon-beta-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0033138-&&-positive regulation of peptidyl-serine phosphorylation-%%-GO:0002741-&&-positive regulation of cytokine secretion involved in immune response-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:1901222-&&-regulation of NIK/NF-kappaB signaling|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:1990782-&&-protein tyrosine kinase binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0019901-&&-protein kinase binding	G:9606:TRIM6				TRIM6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM6	0.34592326	0.83333333	6	4	FALSE	TRIM6	TRIM6	284.75	0	5	0	0.68486424	FALSE	1	TRIM6	202	0.278348
792449	taxon:9606	2.87773751	9.04E-06	182007	1902	chymotrypsinogen B1	gene	biological_process-&-1&-GO:0007586-&&-digestion-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0009235-&&-cobalamin metabolic process-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008236-&&-serine-type peptidase activity-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:CTRB1	CTRB1	TRUE	KEGG-&-1&-hsa04974-&&-Protein digestion and absorption-%%-hsa04972-&&-Pancreatic secretion	CTRB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CTRB1	0.34749521	0.06666667	6	4	FALSE	CTRB1	CTRB1	194.6666667	0	6	0	0.68704375	FALSE	0	CTRB1	8692	0.17259786
792456	taxon:9606	3.01039861	8.30E-07	181991	1902	cut like homeobox 1	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0050775-&&-positive regulation of dendrite morphogenesis-%%-GO:0048193-&&-Golgi vesicle transport-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0000301-&&-retrograde transport, vesicle recycling within Golgi-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0030674-&&-protein binding, bridging-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:CUX1				CUX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CUX1	0.33218192	0	6	5	FALSE	CUX1	CUX1	97.83333333	0	6	0	0.66493356	FALSE	0	CUX1	1504	0.18621795
792529	taxon:9606	3.02505121	4.66E-06	181850	1902	cathelicidin antimicrobial peptide	gene	biological_process-&-1&-GO:0044140-&&-negative regulation of growth of symbiont on or near host surface-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0051873-&&-killing by host of symbiont cells-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0042581-&&-specific granule-%%-GO:0035580-&&-specific granule lumen	G:9606:CAMP			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa04970-&&-Salivary secretion-%%-hsa05150-&&-Staphylococcus aureus infection	CAMP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMP	0.33057292	0	6	5	FALSE	CAMP	CAMP	62.5	0	6	0	0.66249147	FALSE	0	CAMP	3430	0.18524096
792572	taxon:9606	2.9404443	1.87E-06	165410	1902	transmembrane 4 L six family member 19	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TM4SF19				TM4SF19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TM4SF19	0.34008466	0.06666667	6	5	FALSE	TM4SF19	TM4SF19	137.5	0	6	0	0.67659262	FALSE	0	TM4SF19	2724	0.19631755
792676	taxon:9606	2.80116591	7.68E-06	165194	1902	CKLF like MARVEL transmembrane domain containing 3	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0050861-&&-positive regulation of B cell receptor signaling pathway|cellular_component-&-1&-GO:0031965-&&-nuclear membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:CMTM3				CMTM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMTM3	0.35699421	0.13333333	6	5	FALSE	CMTM3	CMTM3	262.1666667	0	6	0	0.69980568	FALSE	0	CMTM3	14180	0.18571091
792708	taxon:9606	2.65794864	2.21E-06	181524	1902	DFNA5, deafness associated tumor suppressor	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:2001244-&&-positive regulation of intrinsic apoptotic signaling pathway-%%-GO:0060113-&&-inner ear receptor cell differentiation-%%-GO:0012501-&&-programmed cell death|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol	G:9606:DFNA5				DFNA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DFNA5	0.37622999	0.26666667	6	4	FALSE	DFNA5	DFNA5	563.6666667	0	6	0	0.72367523	FALSE	0	DFNA5	6304	0.24805519
792731	taxon:9606	2.96565306	2.91E-06	181481	1902	deleted in malignant brain tumors 1	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0043152-&&-induction of bacterial agglutination-%%-GO:0002221-&&-pattern recognition receptor signaling pathway-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0015031-&&-protein transport-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0051607-&&-defense response to virus-%%-GO:0007275-&&-multicellular organism development-%%-GO:0044267-&&-cellular protein metabolic process|cellular_component-&-1&-GO:0042589-&&-zymogen granule membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:0005515-&&-protein binding-%%-GO:0035375-&&-zymogen binding-%%-GO:0008329-&&-signaling pattern recognition receptor activity	G:9606:DMBT1			KEGG-&-1&-hsa04970-&&-Salivary secretion	DMBT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMBT1	0.33719386	0	6	5	FALSE	DMBT1	DMBT1	102.8333333	0	6	0	0.67239116	FALSE	0	DMBT1	3380	0.17679398
792760	taxon:9606	3.00708996	1.85E-06	181421	1902	fibroblast growth factor 5	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0023019-&&-signal transduction involved in regulation of gene expression-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007399-&&-nervous system development-%%-GO:0000165-&&-MAPK cascade-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0008283-&&-cell proliferation-%%-GO:0010001-&&-glial cell differentiation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0051781-&&-positive regulation of cell division|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005104-&&-fibroblast growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:FGF5			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa05224-&&-Breast cancer-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05226-&&-Gastric cancer	FGF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGF5	0.33254742	0.06666667	6	5	FALSE	FGF5	FGF5	82.5	0	6	0	0.66548501	FALSE	0	FGF5	2040	0.1864085
792761	taxon:9606	3.03907358	2.34E-06	181416	1902	fibroblast growth factor 10	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0045931-&&-positive regulation of mitotic cell cycle-%%-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0001759-&&-organ induction-%%-GO:0034394-&&-protein localization to cell surface-%%-GO:0042246-&&-tissue regeneration-%%-GO:0048538-&&-thymus development-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0042693-&&-muscle cell fate commitment-%%-GO:0060428-&&-lung epithelium development-%%-GO:0060510-&&-Type II pneumocyte differentiation-%%-GO:0045739-&&-positive regulation of DNA repair-%%-GO:0060430-&&-lung saccule development-%%-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0030878-&&-thyroid gland development-%%-GO:0048807-&&-female genitalia morphogenesis-%%-GO:0060664-&&-epithelial cell proliferation involved in salivary gland morphogenesis-%%-GO:0007431-&&-salivary gland development-%%-GO:0008543-&&-fibroblast growth factor receptor signaling pathway-%%-GO:0060513-&&-prostatic bud formation-%%-GO:0071338-&&-positive regulation of hair follicle cell proliferation-%%-GO:0001823-&&-mesonephros development-%%-GO:0032808-&&-lacrimal gland development-%%-GO:0010631-&&-epithelial cell migration-%%-GO:0030949-&&-positive regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0060915-&&-mesenchymal cell differentiation involved in lung development-%%-GO:0048557-&&-embryonic digestive tract morphogenesis-%%-GO:0008589-&&-regulation of smoothened signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0061115-&&-lung proximal/distal axis specification-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0050677-&&-positive regulation of urothelial cell proliferation-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0061033-&&-secretion by lung epithelial cell involved in lung growth-%%-GO:0000165-&&-MAPK cascade-%%-GO:0031016-&&-pancreas development-%%-GO:0001525-&&-angiogenesis-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0001656-&&-metanephros development-%%-GO:0060661-&&-submandibular salivary gland formation-%%-GO:0060436-&&-bronchiole morphogenesis-%%-GO:0032355-&&-response to estradiol-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0060449-&&-bud elongation involved in lung branching-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0070075-&&-tear secretion-%%-GO:0048808-&&-male genitalia morphogenesis-%%-GO:0042060-&&-wound healing-%%-GO:0030538-&&-embryonic genitalia morphogenesis-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0031659-&&-positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle-%%-GO:0050918-&&-positive chemotaxis-%%-GO:0060019-&&-radial glial cell differentiation-%%-GO:0036092-&&-phosphatidylinositol-3-phosphate biosynthetic process-%%-GO:0000132-&&-establishment of mitotic spindle orientation-%%-GO:0050872-&&-white fat cell differentiation-%%-GO:0060595-&&-fibroblast growth factor receptor signaling pathway involved in mammary gland specification-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060667-&&-branch elongation involved in salivary gland morphogenesis-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0050671-&&-positive regulation of lymphocyte proliferation-%%-GO:0050673-&&-epithelial cell proliferation-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0046877-&&-regulation of saliva secretion-%%-GO:0032925-&&-regulation of activin receptor signaling pathway-%%-GO:0060054-&&-positive regulation of epithelial cell proliferation involved in wound healing-%%-GO:0030916-&&-otic vesicle formation-%%-GO:0070371-&&-ERK1 and ERK2 cascade-%%-GO:0050674-&&-urothelial cell proliferation-%%-GO:2001240-&&-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand-%%-GO:0046579-&&-positive regulation of Ras protein signal transduction-%%-GO:0031076-&&-embryonic camera-type eye development-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0048536-&&-spleen development-%%-GO:0060615-&&-mammary gland bud formation-%%-GO:0060665-&&-regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0051549-&&-positive regulation of keratinocyte migration-%%-GO:0060496-&&-mesenchymal-epithelial cell signaling involved in lung development-%%-GO:0070384-&&-Harderian gland development-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:0003338-&&-metanephros morphogenesis-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0001974-&&-blood vessel remodeling-%%-GO:0021983-&&-pituitary gland development-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0048754-&&-branching morphogenesis of an epithelial tube-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0051145-&&-smooth muscle cell differentiation-%%-GO:0070352-&&-positive regulation of white fat cell proliferation-%%-GO:0009880-&&-embryonic pattern specification-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0060174-&&-limb bud formation-%%-GO:0060447-&&-bud outgrowth involved in lung branching-%%-GO:0060879-&&-semicircular canal fusion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008201-&&-heparin binding-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0016303-&&-1-phosphatidylinositol-3-kinase activity-%%-GO:0005104-&&-fibroblast growth factor receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0005111-&&-type 2 fibroblast growth factor receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:FGF10			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05218-&&-Melanoma-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa05200-&&-Pathways in cancer-%%-hsa05226-&&-Gastric cancer	FGF10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FGF10	0.32904764	0	6	5	FALSE	FGF10	FGF10	80.5	0	6	0	0.6601544	FALSE	0	FGF10	2060	0.18233945
792775	taxon:9606	2.78320466	3.80E-06	165011	1902	ring finger protein 19B	gene	biological_process-&-1&-GO:0032436-&&-positive regulation of proteasomal ubiquitin-dependent protein catabolic process-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0002250-&&-adaptive immune response|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0044194-&&-cytolytic granule|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031624-&&-ubiquitin conjugating enzyme binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:RNF19B				RNF19B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF19B	0.35929805	0.2	6	4	FALSE	RNF19B	RNF19B	307.6666667	0	6	0	0.70279922	FALSE	0	RNF19B	4208	0.20166229
792832	taxon:9606	2.86340003	4.20E-07	181294	1902	EPH receptor A1	gene	biological_process-&-1&-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0051496-&&-positive regulation of stress fiber assembly-%%-GO:0001525-&&-angiogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0035019-&&-somatic stem cell population maintenance-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005005-&&-transmembrane-ephrin receptor activity-%%-GO:0019901-&&-protein kinase binding	G:9606:EPHA1			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA1	0.34923517	0.33333333	6	5	FALSE	EPHA1	EPHA1	233	0	6	0	0.68943333	FALSE	0	EPHA1	1098	0.20953237
792941	taxon:9606	3.30297778	2.02E-06	181110	1902	Fanconi anemia complementation group B	gene	biological_process-&-1&-GO:0036297-&&-interstrand cross-link repair|cellular_component-&-1&-GO:0043240-&&-Fanconi anaemia nuclear complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:FANCB			KEGG-&-1&-hsa03460-&&-Fanconi anemia pathway	FANCB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FANCB	0.30275711	0.33333333	6	5	FALSE	FANCB	FANCB	23.66666667	0	6	0	0.61617037	FALSE	0	FANCB	956	0.20289855
792958	taxon:9606	2.93492989	1.89E-06	164703	1902	keratin 72	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:KRT72				KRT72	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT72	0.34072364	0.06666667	6	5	FALSE	KRT72	KRT72	148.5	0	6	0	0.67751169	FALSE	0	KRT72	3622	0.18433084
793000	taxon:9606	2.91318733	5.30E-07	181013	1902	formyl peptide receptor 1	gene	biological_process-&-1&-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0050900-&&-leukocyte migration-%%-GO:0007165-&&-signal transduction-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0002430-&&-complement receptor mediated signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030667-&&-secretory granule membrane-%%-GO:0035577-&&-azurophil granule membrane|molecular_function-&-1&-GO:0004875-&&-complement receptor activity-%%-GO:0050786-&&-RAGE receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004982-&&-N-formyl peptide receptor activity	G:9606:FPR1			KEGG-&-1&-hsa04015-&&-Rap1 signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05150-&&-Staphylococcus aureus infection	FPR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FPR1	0.34326663	0.13333333	6	5	FALSE	FPR1	FPR1	151.1666667	0	6	0	0.68113544	FALSE	0	FPR1	1424	0.20300583
793003	taxon:9606	2.75783835	7.30E-07	164615	1902	junction mediating and regulatory protein, p53 cofactor	gene	biological_process-&-1&-GO:0070358-&&-actin polymerization-dependent cell motility-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0070060-&&-'de novo' actin filament nucleation-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0006281-&&-DNA repair-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0034314-&&-Arp2/3 complex-mediated actin nucleation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0031252-&&-cell leading edge-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005856-&&-cytoskeleton|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0005515-&&-protein binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0071933-&&-Arp2/3 complex binding	G:9606:JMY				JMY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JMY	0.36260283	0.4	6	4	FALSE	JMY	JMY	374.6666667	0	6	0	0.70702694	FALSE	0	JMY	1638	0.2264208
793042	taxon:9606	3.08429179	2.98E-06	180851	1902	glutamate metabotropic receptor 2	gene	biological_process-&-1&-GO:0051966-&&-regulation of synaptic transmission, glutamatergic-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0014047-&&-glutamate secretion-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0007196-&&-adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway-%%-GO:0007216-&&-G-protein coupled glutamate receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030425-&&-dendrite-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030424-&&-axon-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008066-&&-glutamate receptor activity-%%-GO:0005246-&&-calcium channel regulator activity-%%-GO:0001641-&&-group II metabotropic glutamate receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:GRM2			KEGG-&-1&-hsa04724-&&-Glutamatergic synapse-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05030-&&-Cocaine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GRM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRM2	0.32422354	0.06666667	6	5	FALSE	GRM2	GRM2	66.33333333	0	6	0	0.65261803	FALSE	0	GRM2	2712	0.17795845
793106	taxon:9606	2.95746022	5.52E-06	180723	1902	glucagon receptor	gene	biological_process-&-1&-GO:0071377-&&-cellular response to glucagon stimulus-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0006887-&&-exocytosis-%%-GO:0070873-&&-regulation of glycogen metabolic process-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007584-&&-response to nutrient-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0042594-&&-response to starvation-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0009755-&&-hormone-mediated signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0004967-&&-glucagon receptor activity-%%-GO:0017046-&&-peptide hormone binding	G:9606:GCGR			KEGG-&-1&-hsa04922-&&-Glucagon signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GCGR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCGR	0.33812796	0.13333333	6	5	FALSE	GCGR	GCGR	120.3333333	0	6	0	0.67375663	FALSE	0	GCGR	4392	0.18435897
793130	taxon:9606	2.9867654	2.34E-06	180673	1902	gap junction protein alpha 5	gene	biological_process-&-1&-GO:0010652-&&-positive regulation of cell communication by chemical coupling-%%-GO:0098905-&&-regulation of bundle of His cell action potential-%%-GO:0055085-&&-transmembrane transport-%%-GO:0098906-&&-regulation of Purkinje myocyte action potential-%%-GO:0003174-&&-mitral valve development-%%-GO:0035050-&&-embryonic heart tube development-%%-GO:0098910-&&-regulation of atrial cardiac muscle cell action potential-%%-GO:0003284-&&-septum primum development-%%-GO:0086044-&&-atrial cardiac muscle cell to AV node cell communication by electrical coupling-%%-GO:1990029-&&-vasomotion-%%-GO:0016264-&&-gap junction assembly-%%-GO:0051259-&&-protein oligomerization-%%-GO:0001525-&&-angiogenesis-%%-GO:0086015-&&-SA node cell action potential-%%-GO:1900825-&&-regulation of membrane depolarization during cardiac muscle cell action potential-%%-GO:0003281-&&-ventricular septum development-%%-GO:0003158-&&-endothelium development-%%-GO:0010643-&&-cell communication by chemical coupling-%%-GO:0086064-&&-cell communication by electrical coupling involved in cardiac conduction-%%-GO:0003193-&&-pulmonary valve formation-%%-GO:0003161-&&-cardiac conduction system development-%%-GO:0086021-&&-SA node cell to atrial cardiac muscle cell communication by electrical coupling-%%-GO:0086055-&&-Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling-%%-GO:0003283-&&-atrial septum development-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0086054-&&-bundle of His cell to Purkinje myocyte communication by electrical coupling-%%-GO:0003294-&&-atrial ventricular junction remodeling-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0006813-&&-potassium ion transport-%%-GO:0048844-&&-artery morphogenesis-%%-GO:0060412-&&-ventricular septum morphogenesis-%%-GO:0060413-&&-atrial septum morphogenesis-%%-GO:0098904-&&-regulation of AV node cell action potential-%%-GO:0060371-&&-regulation of atrial cardiac muscle cell membrane depolarization-%%-GO:0001501-&&-skeletal system development-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:1900133-&&-regulation of renin secretion into blood stream-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0003105-&&-negative regulation of glomerular filtration-%%-GO:0035922-&&-foramen ovale closure-%%-GO:0003151-&&-outflow tract morphogenesis-%%-GO:0060373-&&-regulation of ventricular cardiac muscle cell membrane depolarization-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0086053-&&-AV node cell to bundle of His cell communication by electrical coupling-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction|cellular_component-&-1&-GO:0005922-&&-connexin complex-%%-GO:0005921-&&-gap junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0042995-&&-cell projection-%%-GO:0014704-&&-intercalated disc|molecular_function-&-1&-GO:0086020-&&-gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling-%%-GO:0086076-&&-gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling-%%-GO:0086075-&&-gap junction channel activity involved in cardiac conduction electrical coupling-%%-GO:0086078-&&-gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling-%%-GO:0071253-&&-connexin binding-%%-GO:0055077-&&-gap junction hemi-channel activity-%%-GO:0086077-&&-gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling-%%-GO:0086079-&&-gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling	G:9606:GJA5				GJA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJA5	0.33481036	0.2	6	5	FALSE	GJA5	GJA5	96	0	6	0	0.66887243	FALSE	0	GJA5	2250	0.17951128
793141	taxon:9606	3.152513	5.79E-06	180662	1902	glypican 3	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0072180-&&-mesonephric duct morphogenesis-%%-GO:0035116-&&-embryonic hindlimb morphogenesis-%%-GO:0072138-&&-mesenchymal cell proliferation involved in ureteric bud development-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0006027-&&-glycosaminoglycan catabolic process-%%-GO:0030282-&&-bone mineralization-%%-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process-%%-GO:0010466-&&-negative regulation of peptidase activity-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:0072203-&&-cell proliferation involved in metanephros development-%%-GO:0045879-&&-negative regulation of smoothened signaling pathway-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0010171-&&-body morphogenesis-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway-%%-GO:0060976-&&-coronary vasculature development-%%-GO:0030324-&&-lung development-%%-GO:0009948-&&-anterior/posterior axis specification-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0046326-&&-positive regulation of glucose import-%%-GO:0030316-&&-osteoclast differentiation-%%-GO:0045807-&&-positive regulation of endocytosis-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0046658-&&-anchored component of plasma membrane-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0043395-&&-heparan sulfate proteoglycan binding-%%-GO:0060422-&&-peptidyl-dipeptidase inhibitor activity	G:9606:GPC3			KEGG-&-1&-hsa05205-&&-Proteoglycans in cancer	GPC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPC3	0.31720726	0	6	5	FALSE	GPC3	GPC3	32.33333333	0	6	0	0.64124783	FALSE	0	GPC3	2600	0.17028986
793178	taxon:9606	2.73436269	4.46E-06	180577	1902	homeobox C10	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0050905-&&-neuromuscular process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0001501-&&-skeletal system development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0021520-&&-spinal cord motor neuron cell fate specification-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0030326-&&-embryonic limb morphogenesis|cellular_component-&-1&-GO:0019907-&&-cyclin-dependent protein kinase activating kinase holoenzyme complex-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:HOXC10				HOXC10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXC10	0.36571593	0.06666667	6	5	FALSE	HOXC10	HOXC10	359.3333333	0	6	0	0.71093955	FALSE	0	HOXC10	4864	0.19652968
793254	taxon:9606	2.9735308	4.65E-06	180442	1902	glycosylphosphatidylinositol specific phospholipase D1	gene	biological_process-&-1&-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0001503-&&-ossification-%%-GO:0035690-&&-cellular response to drug-%%-GO:0010595-&&-positive regulation of endothelial cell migration-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0010897-&&-negative regulation of triglyceride catabolic process-%%-GO:0002430-&&-complement receptor mediated signaling pathway-%%-GO:0010694-&&-positive regulation of alkaline phosphatase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0010983-&&-positive regulation of high-density lipoprotein particle clearance-%%-GO:0046470-&&-phosphatidylcholine metabolic process-%%-GO:0070633-&&-transepithelial transport-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0071467-&&-cellular response to pH-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0006507-&&-GPI anchor release-%%-GO:0035701-&&-hematopoietic stem cell migration-%%-GO:0051044-&&-positive regulation of membrane protein ectodomain proteolysis-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:1900076-&&-regulation of cellular response to insulin stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0045919-&&-positive regulation of cytolysis-%%-GO:0071401-&&-cellular response to triglyceride-%%-GO:0009749-&&-response to glucose-%%-GO:0035774-&&-positive regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0051047-&&-positive regulation of secretion-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0097241-&&-hematopoietic stem cell migration to bone marrow-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0071397-&&-cellular response to cholesterol|cellular_component-&-1&-GO:0005765-&&-lysosomal membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004621-&&-glycosylphosphatidylinositol phospholipase D activity-%%-GO:0004630-&&-phospholipase D activity-%%-GO:0017080-&&-sodium channel regulator activity	G:9606:GPLD1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00563-&&-Glycosylphosphatidylinositol (GPI)-anchor biosynthesis	GPLD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPLD1	0.33630054	0.2	6	5	FALSE	GPLD1	GPLD1	114	0	6	0	0.6710782	FALSE	0	GPLD1	4234	0.18791391
793301	taxon:9606	2.96328974	2.40E-07	180354	1902	hemoglobin subunit epsilon 1	gene	biological_process-&-1&-GO:0015671-&&-oxygen transport-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0007596-&&-blood coagulation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005833-&&-hemoglobin complex-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0019825-&&-oxygen binding-%%-GO:0005344-&&-oxygen transporter activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0020037-&&-heme binding-%%-GO:0031721-&&-hemoglobin alpha binding	G:9606:HBE1				HBE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HBE1	0.33746278	0.66666667	6	5	FALSE	HBE1	HBE1	200.3333333	0	6	0	0.67278504	FALSE	0	HBE1	692	0.27367942
787027	taxon:9606	2.82164802	3.00E-06	180211	1902	inter-alpha-trypsin inhibitor heavy chain family member 4	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030212-&&-hyaluronan metabolic process-%%-GO:0034097-&&-response to cytokine-%%-GO:0006953-&&-acute-phase response-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031089-&&-platelet dense granule lumen-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004866-&&-endopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:ITIH4				ITIH4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITIH4	0.35440281	0.2	5	5	FALSE	ITIH4	ITIH4	331.6	0	5	0	0.696392	FALSE	0	ITIH4	3558	0.25321101
787036	taxon:9606	2.96250197	2.57E-06	180190	1902	homeobox B2	gene	biological_process-&-1&-GO:0021612-&&-facial nerve structural organization-%%-GO:0002011-&&-morphogenesis of an epithelial sheet-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0021570-&&-rhombomere 4 development-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0007275-&&-multicellular organism development-%%-GO:0021569-&&-rhombomere 3 development-%%-GO:0008015-&&-blood circulation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0048857-&&-neural nucleus development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:HOXB2				HOXB2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXB2	0.33755252	0.1	5	4	FALSE	HOXB2	HOXB2	194	0	5	0	0.67291634	FALSE	0	HOXB2	3268	0.26277174
787058	taxon:9606	3.50023633	6.10E-07	180148	1902	interferon alpha 1	gene	biological_process-&-1&-GO:0002250-&&-adaptive immune response-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0002323-&&-natural killer cell activation involved in immune response-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006959-&&-humoral immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0007596-&&-blood coagulation-%%-GO:0033141-&&-positive regulation of peptidyl-serine phosphorylation of STAT protein-%%-GO:0042100-&&-B cell proliferation-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0005132-&&-type I interferon receptor binding	G:9606:IFNA1			KEGG-&-1&-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05162-&&-Measles-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	IFNA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNA1	0.28569499	0.2	5	5	FALSE	IFNA1	IFNA1	15.8	0	5	0	0.58329394	FALSE	0	IFNA1	480	0.26101695
787061	taxon:9606	3.50023633	6.10E-07	180140	1902	interferon alpha 13	gene	biological_process-&-1&-GO:0002250-&&-adaptive immune response-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0002323-&&-natural killer cell activation involved in immune response-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006959-&&-humoral immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0007596-&&-blood coagulation-%%-GO:0033141-&&-positive regulation of peptidyl-serine phosphorylation of STAT protein-%%-GO:0042100-&&-B cell proliferation-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0005132-&&-type I interferon receptor binding	G:9606:IFNA13			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05164-&&-Influenza A-%%-hsa05161-&&-Hepatitis B-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	IFNA13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNA13	0.28569499	0.2	5	5	FALSE	IFNA13	IFNA13	15.8	0	5	0	0.58329394	FALSE	0	IFNA13	480	0.26101695
787072	taxon:9606	3.02284544	2.19E-06	180116	1902	insulin like growth factor binding protein acid labile subunit	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0042567-&&-insulin-like growth factor ternary complex|molecular_function-&-1&-GO:0005520-&&-insulin-like growth factor binding	G:9606:IGFALS				IGFALS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFALS	0.33081414	0.2	5	5	FALSE	IGFALS	IGFALS	91.8	0	5	0	0.66285909	FALSE	0	IGFALS	2704	0.21658768
787089	taxon:9606	3.03261383	3.34E-06	180090	1902	immunoglobulin kappa constant	gene	biological_process-&-1&-GO:0038095-&&-Fc-epsilon receptor signaling pathway-%%-GO:0038096-&&-Fc-gamma receptor signaling pathway involved in phagocytosis-%%-GO:0001895-&&-retina homeostasis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006955-&&-immune response-%%-GO:0006958-&&-complement activation, classical pathway-%%-GO:0006956-&&-complement activation-%%-GO:0045087-&&-innate immune response-%%-GO:0006508-&&-proteolysis-%%-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0006910-&&-phagocytosis, recognition-%%-GO:0002377-&&-immunoglobulin production-%%-GO:0050871-&&-positive regulation of B cell activation-%%-GO:0006911-&&-phagocytosis, engulfment-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0050776-&&-regulation of immune response|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0042571-&&-immunoglobulin complex, circulating-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0003823-&&-antigen binding-%%-GO:0034987-&&-immunoglobulin receptor binding	G:9606:IGKC				IGKC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGKC	0.32974855	0.1	5	5	FALSE	IGKC	IGKC	79.6	0	5	0	0.66123103	FALSE	0	IGKC	2342	0.20680628
787117	taxon:9606	3.42256184	4.11E-05	180035	1902	interleukin 10	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:1903034-&&-regulation of response to wounding-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:0032689-&&-negative regulation of interferon-gamma production-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:1904706-&&-negative regulation of vascular smooth muscle cell proliferation-%%-GO:0007253-&&-cytoplasmic sequestering of NF-kappaB-%%-GO:0030183-&&-B cell differentiation-%%-GO:0030886-&&-negative regulation of myeloid dendritic cell activation-%%-GO:0032868-&&-response to insulin-%%-GO:0050807-&&-regulation of synapse organization-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0045355-&&-negative regulation of interferon-alpha biosynthetic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0030595-&&-leukocyte chemotaxis-%%-GO:0035729-&&-cellular response to hepatocyte growth factor stimulus-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0002740-&&-negative regulation of cytokine secretion involved in immune response-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0032717-&&-negative regulation of interleukin-8 production-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0002237-&&-response to molecule of bacterial origin-%%-GO:0014854-&&-response to inactivity-%%-GO:0045930-&&-negative regulation of mitotic cell cycle-%%-GO:0045787-&&-positive regulation of cell cycle-%%-GO:0002904-&&-positive regulation of B cell apoptotic process-%%-GO:0030097-&&-hemopoiesis-%%-GO:0032800-&&-receptor biosynthetic process-%%-GO:0042100-&&-B cell proliferation-%%-GO:0045347-&&-negative regulation of MHC class II biosynthetic process-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:0042493-&&-response to drug-%%-GO:0032695-&&-negative regulation of interleukin-12 production-%%-GO:0045191-&&-regulation of isotype switching-%%-GO:0032701-&&-negative regulation of interleukin-18 production-%%-GO:0032715-&&-negative regulation of interleukin-6 production-%%-GO:0034115-&&-negative regulation of heterotypic cell-cell adhesion-%%-GO:0034465-&&-response to carbon monoxide-%%-GO:0071650-&&-negative regulation of chemokine (C-C motif) ligand 5 production-%%-GO:0030889-&&-negative regulation of B cell proliferation-%%-GO:0042536-&&-negative regulation of tumor necrosis factor biosynthetic process-%%-GO:0034116-&&-positive regulation of heterotypic cell-cell adhesion-%%-GO:0060670-&&-branching involved in labyrinthine layer morphogenesis-%%-GO:0050715-&&-positive regulation of cytokine secretion-%%-GO:1904057-&&-negative regulation of sensory perception of pain-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:1904707-&&-positive regulation of vascular smooth muscle cell proliferation-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0051091-&&-positive regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0060302-&&-negative regulation of cytokine activity-%%-GO:0007568-&&-aging-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0002875-&&-negative regulation of chronic inflammatory response to antigenic stimulus-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0072577-&&-endothelial cell apoptotic process-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0032692-&&-negative regulation of interleukin-1 production-%%-GO:0006954-&&-inflammatory response-%%-GO:0042092-&&-type 2 immune response-%%-GO:0045348-&&-positive regulation of MHC class II biosynthetic process-%%-GO:0042832-&&-defense response to protozoan-%%-GO:1903659-&&-regulation of complement-dependent cytotoxicity-%%-GO:0014823-&&-response to activity-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0097421-&&-liver regeneration|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005141-&&-interleukin-10 receptor binding	G:9606:IL10	IL10	TRUE	KEGG-&-1&-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05330-&&-Allograft rejection-%%-hsa05310-&&-Asthma-%%-hsa04068-&&-FoxO signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05140-&&-Leishmaniasis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05150-&&-Staphylococcus aureus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05143-&&-African trypanosomiasis-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05146-&&-Amoebiasis-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa05144-&&-Malaria-%%-hsa04660-&&-T cell receptor signaling pathway	IL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL10	0.2921788	0.33333333	5	5	FALSE	IL10	IL10	29.66666667	0	4	0	0.59623969	FALSE	1	IL10	18590	0.34108527
787123	taxon:9606	2.97164014	8.39E-06	180026	1902	interleukin 13	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0035094-&&-response to nicotine-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:1903660-&&-negative regulation of complement-dependent cytotoxicity-%%-GO:0030890-&&-positive regulation of B cell proliferation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0051281-&&-positive regulation of release of sequestered calcium ion into cytosol-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0033861-&&-negative regulation of NAD(P)H oxidase activity-%%-GO:0043306-&&-positive regulation of mast cell degranulation-%%-GO:0043032-&&-positive regulation of macrophage activation-%%-GO:1901247-&&-negative regulation of lung ciliated cell differentiation-%%-GO:0001774-&&-microglial cell activation-%%-GO:0007165-&&-signal transduction-%%-GO:0045471-&&-response to ethanol-%%-GO:0032723-&&-positive regulation of connective tissue growth factor production-%%-GO:0006954-&&-inflammatory response-%%-GO:0071635-&&-negative regulation of transforming growth factor beta production-%%-GO:2000231-&&-positive regulation of pancreatic stellate cell proliferation-%%-GO:1901251-&&-positive regulation of lung goblet cell differentiation-%%-GO:2000352-&&-negative regulation of endothelial cell apoptotic process-%%-GO:0042526-&&-positive regulation of tyrosine phosphorylation of Stat6 protein-%%-GO:0002639-&&-positive regulation of immunoglobulin production-%%-GO:0006955-&&-immune response-%%-GO:0010155-&&-regulation of proton transport-%%-GO:0071260-&&-cellular response to mechanical stimulus-%%-GO:1901215-&&-negative regulation of neuron death|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0005144-&&-interleukin-13 receptor binding	G:9606:IL13			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa05310-&&-Asthma-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04664-&&-Fc epsilon RI signaling pathway-%%-hsa04657-&&-IL-17 signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa05200-&&-Pathways in cancer-%%-hsa04658-&&-Th1 and Th2 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL13	0.3365145	0.1	5	5	FALSE	IL13	IL13	145	0	5	0	0.67139331	FALSE	0	IL13	10600	0.21297935
787175	taxon:9606	3.09689617	5.85E-06	179923	1902	tumor-associated calcium signal transducer 2	gene	biological_process-&-1&-GO:0090191-&&-negative regulation of branching involved in ureteric bud morphogenesis-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:2000738-&&-positive regulation of stem cell differentiation-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0060675-&&-ureteric bud morphogenesis-%%-GO:1900028-&&-negative regulation of ruffle assembly-%%-GO:0010633-&&-negative regulation of epithelial cell migration-%%-GO:0007601-&&-visual perception-%%-GO:1900025-&&-negative regulation of substrate adhesion-dependent cell spreading-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:2000146-&&-negative regulation of cell motility-%%-GO:0008283-&&-cell proliferation-%%-GO:0098609-&&-cell-cell adhesion|cellular_component-&-1&-GO:0016328-&&-lateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005634-&&-nucleus-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:TACSTD2				TACSTD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TACSTD2	0.32290395	0.2	5	5	FALSE	TACSTD2	TACSTD2	69.6	0	5	0	0.6505173	FALSE	0	TACSTD2	5222	0.2116208
787182	taxon:9606	3.02095478	6.00E-08	163524	1902	zinc finger protein 431	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001046-&&-core promoter sequence-specific DNA binding	G:9606:ZNF431				ZNF431	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF431	0.33102117	0.2	5	5	FALSE	ZNF431	ZNF431	183.8	0	5	0	0.6631742	FALSE	0	ZNF431	514	0.38571429
787199	taxon:9606	3.17378289	1.35E-06	179887	1902	MAGE family member A12	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:MAGEA12				MAGEA12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAGEA12	0.31508141	0	5	5	FALSE	MAGEA12	MAGEA12	38.2	0	5	0	0.63770285	FALSE	0	MAGEA12	1020	0.20552486
787278	taxon:9606	2.9700646	2.01E-06	179755	1902	potassium voltage-gated channel subfamily E regulatory subunit 1	gene	biological_process-&-1&-GO:0006487-&&-protein N-linked glycosylation-%%-GO:0086011-&&-membrane repolarization during action potential-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:1901381-&&-positive regulation of potassium ion transmembrane transport-%%-GO:1902259-&&-regulation of delayed rectifier potassium channel activity-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:0006493-&&-protein O-linked glycosylation-%%-GO:0086013-&&-membrane repolarization during cardiac muscle cell action potential-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:0090315-&&-negative regulation of protein targeting to membrane-%%-GO:0061337-&&-cardiac conduction-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0071435-&&-potassium ion export-%%-GO:0086009-&&-membrane repolarization-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005764-&&-lysosome-%%-GO:0030018-&&-Z disc-%%-GO:0045121-&&-membrane raft|molecular_function-&-1&-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0031433-&&-telethonin binding-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0086008-&&-voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0015459-&&-potassium channel regulator activity	G:9606:KCNE1			KEGG-&-1&-hsa04261-&&-Adrenergic signaling in cardiomyocytes	KCNE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNE1	0.33669301	0	5	5	FALSE	KCNE1	KCNE1	130.6	0	5	0	0.6716559	FALSE	0	KCNE1	2958	0.2156406
787289	taxon:9606	2.87364109	4.90E-07	163344	1902	zinc finger protein 366	gene	biological_process-&-1&-GO:0033147-&&-negative regulation of intracellular estrogen receptor signaling pathway-%%-GO:0043627-&&-response to estrogen-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0030331-&&-estrogen receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0005515-&&-protein binding	G:9606:ZNF366				ZNF366	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF366	0.34799057	0.3	5	5	FALSE	ZNF366	ZNF366	243.2	0	5	0	0.68772648	FALSE	0	ZNF366	1470	0.22731525
787302	taxon:9606	3.36836301	1.95E-06	179696	1902	kallikrein B1	gene	biological_process-&-1&-GO:0051919-&&-positive regulation of fibrinolysis-%%-GO:0007597-&&-blood coagulation, intrinsic pathway-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0031639-&&-plasminogen activation-%%-GO:0006508-&&-proteolysis-%%-GO:0042730-&&-fibrinolysis-%%-GO:0031638-&&-zymogen activation-%%-GO:0002542-&&-Factor XII activation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:KLKB1			KEGG-&-1&-hsa04610-&&-Complement and coagulation cascades	KLKB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLKB1	0.29688012	0	5	5	FALSE	KLKB1	KLKB1	19.8	0	5	0	0.60527283	FALSE	0	KLKB1	1092	0.21363636
787335	taxon:9606	2.73940444	1.47E-06	179641	1902	keratin 86	gene	biological_process-&-1&-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0045095-&&-keratin filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding	G:9606:KRT86				KRT86	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT86	0.36504285	0.3	5	4	FALSE	KRT86	KRT86	444.8	0	5	0	0.71009926	FALSE	0	KRT86	4072	0.25008441
787356	taxon:9606	3.02599653	5.90E-07	179596	1902	microsomal triglyceride transfer protein	gene	biological_process-&-1&-GO:0042158-&&-lipoprotein biosynthetic process-%%-GO:0034377-&&-plasma lipoprotein particle assembly-%%-GO:0015914-&&-phospholipid transport-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0034197-&&-triglyceride transport|cellular_component-&-1&-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0005548-&&-phospholipid transporter activity-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005319-&&-lipid transporter activity-%%-GO:0005515-&&-protein binding-%%-GO:0008289-&&-lipid binding	G:9606:MTTP	MTTP	TRUE	KEGG-&-1&-hsa04975-&&-Fat digestion and absorption	MTTP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTTP	0.33046964	0.3	5	5	FALSE	MTTP	MTTP	96	0	5	0	0.66233391	FALSE	0	MTTP	840	0.22973621
787364	taxon:9606	2.93288168	1.21E-04	179560	1902	muscle associated receptor tyrosine kinase	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:2000541-&&-positive regulation of protein geranylgeranylation-%%-GO:0007528-&&-neuromuscular junction development-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0008582-&&-regulation of synaptic growth at neuromuscular junction-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007613-&&-memory-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043235-&&-receptor complex-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0045211-&&-postsynaptic membrane|molecular_function-&-1&-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding	G:9606:MUSK				MUSK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MUSK	0.34096159	0.4	5	5	FALSE	MUSK	MUSK	198.6	0	5	0	0.67785305	FALSE	0	MUSK	114784	0.25501285
787410	taxon:9606	3.03103829	1.81E-06	163095	1902	coiled-coil and C2 domain containing 1B	gene	biological_process-&-1&-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0005515-&&-protein binding	G:9606:CC2D1B				CC2D1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CC2D1B	0.32991995	0	5	5	FALSE	CC2D1B	CC2D1B	98	0	5	0	0.66149362	FALSE	0	CC2D1B	2342	0.21086957
787463	taxon:9606	3.00472664	2.11E-06	163011	1902	LysM domain containing 2	gene		G:9606:LYSMD2				LYSMD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYSMD2	0.33280898	0	5	5	FALSE	LYSMD2	LYSMD2	92.8	0	5	0	0.66587889	FALSE	0	LYSMD2	1870	0.21549296
787485	taxon:9606	2.91066646	9.30E-07	179351	1902	mitogen-activated protein kinase kinase kinase 9	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007256-&&-activation of JNKK activity-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0046777-&&-protein autophosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004706-&&-JUN kinase kinase kinase activity-%%-GO:0004708-&&-MAP kinase kinase activity-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MAP3K9				MAP3K9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K9	0.34356393	0	5	5	FALSE	MAP3K9	MAP3K9	321.6666667	0	4	0	0.68155559	FALSE	1	MAP3K9	1300	0.36192626
787500	taxon:9606	3.56215535	2.07E-06	179332	1902	matrix metallopeptidase 8	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0035987-&&-endodermal cell differentiation-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:1904724-&&-tertiary granule lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0035580-&&-specific granule lumen|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:MMP8	MMP8	TRUE		MMP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP8	0.28072891	0	5	5	FALSE	MMP8	MMP8	15	0	5	0	0.57297411	FALSE	0	MMP8	2540	0.23333333
787515	taxon:9606	3.25051205	3.40E-07	179306	1902	myeloperoxidase	gene	biological_process-&-1&-GO:0042744-&&-hydrogen peroxide catabolic process-%%-GO:0002679-&&-respiratory burst involved in defense response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0050832-&&-defense response to fungus-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0002149-&&-hypochlorous acid biosynthetic process-%%-GO:0006952-&&-defense response-%%-GO:0007568-&&-aging-%%-GO:0044130-&&-negative regulation of growth of symbiont in host-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0019430-&&-removal of superoxide radicals-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0042742-&&-defense response to bacterium-%%-GO:0001878-&&-response to yeast-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:1990268-&&-response to gold nanoparticle-%%-GO:0032094-&&-response to food-%%-GO:0034374-&&-low-density lipoprotein particle remodeling|cellular_component-&-1&-GO:0042582-&&-azurophil granule-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005634-&&-nucleus-%%-GO:0005615-&&-extracellular space-%%-GO:0005739-&&-mitochondrion-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0030141-&&-secretory granule-%%-GO:0005764-&&-lysosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0004601-&&-peroxidase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0020037-&&-heme binding-%%-GO:0008201-&&-heparin binding	G:9606:MPO	MPO	TRUE	KEGG-&-1&-hsa05221-&&-Acute myeloid leukemia-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa04145-&&-Phagosome	MPO	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MPO	0.30764384	0.33333333	5	5	FALSE	MPO	MPO	78.66666667	0	4	0	0.62491466	FALSE	1	MPO	386	0.34057971
787524	taxon:9606	2.89963762	9.98E-06	162876	1902	solute carrier family 39 member 11	gene	biological_process-&-1&-GO:0071577-&&-zinc II ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity	G:9606:SLC39A11				SLC39A11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A11	0.34487068	0.1	5	5	FALSE	SLC39A11	SLC39A11	200.2	0	5	0	0.68339373	FALSE	0	SLC39A11	6968	0.20598555
787587	taxon:9606	3.03261383	5.21E-06	179136	1902	neogenin 1	gene	biological_process-&-1&-GO:0055072-&&-iron ion homeostasis-%%-GO:0007411-&&-axon guidance-%%-GO:0007155-&&-cell adhesion-%%-GO:0030513-&&-positive regulation of BMP signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0098797-&&-plasma membrane protein complex-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0039706-&&-co-receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:NEO1			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04350-&&-TGF-beta signaling pathway	NEO1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEO1	0.32974855	0	5	5	FALSE	NEO1	NEO1	69.8	0	5	0	0.66123103	FALSE	0	NEO1	3686	0.2097561
787617	taxon:9606	2.93760832	4.30E-07	179087	1902	natural killer cell triggering receptor	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0000413-&&-protein peptidyl-prolyl isomerization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003755-&&-peptidyl-prolyl cis-trans isomerase activity-%%-GO:0016018-&&-cyclosporin A binding	G:9606:NKTR				NKTR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NKTR	0.34041298	0.4	5	5	FALSE	NKTR	NKTR	186.2	0	5	0	0.67706528	FALSE	0	NKTR	980	0.23659466
787646	taxon:9606	3.03986135	1.38E-06	179023	1902	neurogranin	gene	biological_process-&-1&-GO:0008306-&&-associative learning-%%-GO:1900273-&&-positive regulation of long-term synaptic potentiation-%%-GO:0007165-&&-signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0021537-&&-telencephalon development|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0012510-&&-trans-Golgi network transport vesicle membrane-%%-GO:0044327-&&-dendritic spine head-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0014069-&&-postsynaptic density-%%-GO:0030424-&&-axon-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005547-&&-phosphatidylinositol-3,4,5-trisphosphate binding-%%-GO:0070300-&&-phosphatidic acid binding-%%-GO:0005516-&&-calmodulin binding	G:9606:NRGN				NRGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRGN	0.32896237	0	5	5	FALSE	NRGN	NRGN	95.8	0	5	0	0.66002311	FALSE	0	NRGN	1384	0.26480447
787796	taxon:9606	3.04458799	3.20E-07	162385	1902	JAZF zinc finger 1	gene	biological_process-&-1&-GO:0006629-&&-lipid metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0001650-&&-fibrillar center-%%-GO:0017053-&&-transcriptional repressor complex|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:JAZF1				JAZF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-JAZF1	0.32845167	0.2	5	5	FALSE	JAZF1	JAZF1	96.6	0	5	0	0.65923533	FALSE	0	JAZF1	578	0.25169713
787846	taxon:9606	3.34520246	1.12E-06	162343	1902	signal peptide, CUB domain and EGF like domain containing 3	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0051291-&&-protein heterooligomerization-%%-GO:0030154-&&-cell differentiation-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0045880-&&-positive regulation of smoothened signaling pathway|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:SCUBE3				SCUBE3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCUBE3	0.29893557	0	5	5	FALSE	SCUBE3	SCUBE3	54.66666667	0	4	0	0.60913292	FALSE	1	SCUBE3	1372	0.36507937
788022	taxon:9606	2.79533638	6.30E-07	178375	1902	ribonuclease L	gene	biological_process-&-1&-GO:0055085-&&-transmembrane transport-%%-GO:0006468-&&-protein phosphorylation-%%-GO:2001275-&&-positive regulation of glucose import in response to insulin stimulus-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0045444-&&-fat cell differentiation-%%-GO:0051607-&&-defense response to virus-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0006397-&&-mRNA processing-%%-GO:0006364-&&-rRNA processing-%%-GO:0045071-&&-negative regulation of viral genome replication-%%-GO:0043488-&&-regulation of mRNA stability-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0016363-&&-nuclear matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004521-&&-endoribonuclease activity-%%-GO:0019843-&&-rRNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0004672-&&-protein kinase activity-%%-GO:0043021-&&-ribonucleoprotein complex binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:RNASEL			KEGG-&-1&-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05164-&&-Influenza A	RNASEL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNASEL	0.3577387	0.4	5	4	FALSE	RNASEL	RNASEL	349.6	0	5	0	0.70077727	FALSE	0	RNASEL	1382	0.23704206
788269	taxon:9606	2.96391996	2.40E-07	177971	1902	ribosomal protein S4, Y-linked 1	gene	biological_process-&-1&-GO:0006412-&&-translation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000184-&&-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-%%-GO:0006413-&&-translational initiation-%%-GO:0019083-&&-viral transcription-%%-GO:0006364-&&-rRNA processing-%%-GO:0006614-&&-SRP-dependent cotranslational protein targeting to membrane|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005844-&&-polysome-%%-GO:0022627-&&-cytosolic small ribosomal subunit-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003723-&&-RNA binding-%%-GO:0019843-&&-rRNA binding-%%-GO:0003735-&&-structural constituent of ribosome	G:9606:RPS4Y1			KEGG-&-1&-hsa03010-&&-Ribosome	RPS4Y1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS4Y1	0.33739103	0.1	5	5	FALSE	RPS4Y1	RPS4Y1	245	0	5	0	0.67268001	FALSE	0	RPS4Y1	1562	0.28991696
788337	taxon:9606	2.96754372	3.64E-06	177854	1902	sodium voltage-gated channel alpha subunit 8	gene	biological_process-&-1&-GO:0060078-&&-regulation of postsynaptic membrane potential-%%-GO:0006814-&&-sodium ion transport-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0019228-&&-neuronal action potential-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0007399-&&-nervous system development-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:0007422-&&-peripheral nervous system development-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0033268-&&-node of Ranvier-%%-GO:0005886-&&-plasma membrane-%%-GO:0030018-&&-Z disc-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0001518-&&-voltage-gated sodium channel complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043194-&&-axon initial segment|molecular_function-&-1&-GO:0005248-&&-voltage-gated sodium channel activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:SCN8A				SCN8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCN8A	0.33697903	0	5	5	FALSE	SCN8A	SCN8A	124.6	0	5	0	0.67207605	FALSE	0	SCN8A	2676	0.21164384
788344	taxon:9606	3.58295258	1.68E-06	177839	1902	C-C motif chemokine ligand 3 like 1	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL3L1			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CCL3L1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL3L1	0.27909942	0	5	5	FALSE	CCL3L1	CCL3L1	24	0	5	0	0.5695079	FALSE	0	CCL3L1	2124	0.30666667
788350	taxon:9606	2.83677328	8.90E-07	177828	1902	C-C motif chemokine ligand 18	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007154-&&-cell communication-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0009607-&&-response to biotic stimulus-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0005515-&&-protein binding-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL18			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL18	0.35251319	0.1	5	4	FALSE	CCL18	CCL18	302	0	5	0	0.69387112	FALSE	0	CCL18	3216	0.24189406
788389	taxon:9606	3.05671971	1.75E-06	177755	1902	steroidogenic acute regulatory protein	gene	biological_process-&-1&-GO:0035457-&&-cellular response to interferon-alpha-%%-GO:0042542-&&-response to hydrogen peroxide-%%-GO:0071373-&&-cellular response to luteinizing hormone stimulus-%%-GO:0071333-&&-cellular response to glucose stimulus-%%-GO:0014823-&&-response to activity-%%-GO:0035094-&&-response to nicotine-%%-GO:0051412-&&-response to corticosterone-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0016101-&&-diterpenoid metabolic process-%%-GO:0009635-&&-response to herbicide-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0010288-&&-response to lead ion-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0043627-&&-response to estrogen-%%-GO:0060992-&&-response to fungicide-%%-GO:0006694-&&-steroid biosynthetic process-%%-GO:0071320-&&-cellular response to cAMP-%%-GO:0042747-&&-circadian sleep/wake cycle, REM sleep-%%-GO:0044321-&&-response to leptin-%%-GO:0045471-&&-response to ethanol-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0007584-&&-response to nutrient-%%-GO:0071372-&&-cellular response to follicle-stimulating hormone stimulus-%%-GO:0006700-&&-C21-steroid hormone biosynthetic process-%%-GO:0071236-&&-cellular response to antibiotic-%%-GO:0017143-&&-insecticide metabolic process-%%-GO:0071378-&&-cellular response to growth hormone stimulus-%%-GO:0032869-&&-cellular response to insulin stimulus-%%-GO:0006703-&&-estrogen biosynthetic process-%%-GO:0042493-&&-response to drug-%%-GO:0018963-&&-phthalate metabolic process-%%-GO:0044344-&&-cellular response to fibroblast growth factor stimulus-%%-GO:0071560-&&-cellular response to transforming growth factor beta stimulus-%%-GO:0018894-&&-dibenzo-p-dioxin metabolic process-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071872-&&-cellular response to epinephrine stimulus-%%-GO:0050769-&&-positive regulation of neurogenesis-%%-GO:0007420-&&-brain development-%%-GO:0010212-&&-response to ionizing radiation-%%-GO:0018958-&&-phenol-containing compound metabolic process-%%-GO:0070859-&&-positive regulation of bile acid biosynthetic process-%%-GO:0048168-&&-regulation of neuronal synaptic plasticity-%%-GO:0061370-&&-testosterone biosynthetic process-%%-GO:0032367-&&-intracellular cholesterol transport-%%-GO:0008584-&&-male gonad development-%%-GO:0071549-&&-cellular response to dexamethasone stimulus-%%-GO:0008211-&&-glucocorticoid metabolic process-%%-GO:0018879-&&-biphenyl metabolic process-%%-GO:0008203-&&-cholesterol metabolic process|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0030061-&&-mitochondrial crista-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0005515-&&-protein binding-%%-GO:0017127-&&-cholesterol transporter activity	G:9606:STAR	STAR	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	STAR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STAR	0.32714809	0.2	5	5	FALSE	STAR	STAR	80	0	5	0	0.65721338	FALSE	0	STAR	1406	0.20621762
788454	taxon:9606	2.95588467	8.30E-07	177640	1902	solute carrier family 6 member 2	gene	biological_process-&-1&-GO:0015874-&&-norepinephrine transport-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0055085-&&-transmembrane transport-%%-GO:0015844-&&-monoamine transport-%%-GO:0006810-&&-transport-%%-GO:0051583-&&-dopamine uptake involved in synaptic transmission-%%-GO:0042493-&&-response to drug-%%-GO:0048265-&&-response to pain|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0043005-&&-neuron projection-%%-GO:0009986-&&-cell surface|molecular_function-&-1&-GO:0005330-&&-dopamine:sodium symporter activity-%%-GO:0008504-&&-monoamine transmembrane transporter activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0048487-&&-beta-tubulin binding-%%-GO:0005334-&&-norepinephrine:sodium symporter activity-%%-GO:0043014-&&-alpha-tubulin binding-%%-GO:0005333-&&-norepinephrine transmembrane transporter activity	G:9606:SLC6A2	SLC6A2	TRUE	KEGG-&-1&-hsa04721-&&-Synaptic vesicle cycle	SLC6A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC6A2	0.33830819	0.1	5	5	FALSE	SLC6A2	SLC6A2	142.8	0	5	0	0.67401922	FALSE	0	SLC6A2	1352	0.22571429
788462	taxon:9606	3.33448873	7.51E-06	177604	1902	solute carrier family 18 member A1	gene	biological_process-&-1&-GO:0015842-&&-aminergic neurotransmitter loading into synaptic vesicle-%%-GO:0015844-&&-monoamine transport-%%-GO:0006837-&&-serotonin transport-%%-GO:0006855-&&-drug transmembrane transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0098793-&&-presynapse-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0070083-&&-clathrin-sculpted monoamine transport vesicle membrane|molecular_function-&-1&-GO:0008504-&&-monoamine transmembrane transporter activity-%%-GO:0015222-&&-serotonin transmembrane transporter activity-%%-GO:0015238-&&-drug transmembrane transporter activity	G:9606:SLC18A1			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa05012-&&-Parkinson disease-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa05030-&&-Cocaine addiction-%%-hsa04721-&&-Synaptic vesicle cycle-%%-hsa05031-&&-Amphetamine addiction	SLC18A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC18A1	0.29989605	0	5	5	FALSE	SLC18A1	SLC18A1	23.8	0	5	0	0.61091854	FALSE	0	SLC18A1	7354	0.20917431
788480	taxon:9606	3.21002048	5.12E-06	177570	1902	sphingomyelin phosphodiesterase 2	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006684-&&-sphingomyelin metabolic process-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0046513-&&-ceramide biosynthetic process-%%-GO:2000304-&&-positive regulation of ceramide biosynthetic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0004767-&&-sphingomyelin phosphodiesterase activity-%%-GO:0046872-&&-metal ion binding	G:9606:SMPD2			KEGG-&-1&-hsa04071-&&-Sphingolipid signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00600-&&-Sphingolipid metabolism	SMPD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SMPD2	0.31152449	0	5	5	FALSE	SMPD2	SMPD2	36.4	0	5	0	0.63166325	FALSE	0	SMPD2	4232	0.20344828
788523	taxon:9606	2.84622656	8.10E-07	177510	1902	sperm associated antigen 1	gene	biological_process-&-1&-GO:0070286-&&-axonemal dynein complex assembly-%%-GO:0007338-&&-single fertilization|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016787-&&-hydrolase activity-%%-GO:0005525-&&-GTP binding	G:9606:SPAG1				SPAG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPAG1	0.35134237	0.1	5	4	FALSE	SPAG1	SPAG1	263.4	0	5	0	0.69229557	FALSE	0	SPAG1	1892	0.22891986
788542	taxon:9606	3.11848117	3.48E-06	177465	1902	aldo-keto reductase family 1 member D1	gene	biological_process-&-1&-GO:0030573-&&-bile acid catabolic process-%%-GO:0008207-&&-C21-steroid hormone metabolic process-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0006707-&&-cholesterol catabolic process-%%-GO:0007586-&&-digestion-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005496-&&-steroid binding-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0047787-&&-delta4-3-oxosteroid 5beta-reductase activity	G:9606:AKR1D1			KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis	AKR1D1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1D1	0.32066892	0.1	5	5	FALSE	AKR1D1	AKR1D1	66	0	5	0	0.6469198	FALSE	0	AKR1D1	2492	0.20501567
788638	taxon:9606	2.77832047	2.41E-06	160891	1902	tripartite motif containing 59	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0043124-&&-negative regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0060271-&&-cilium assembly-%%-GO:0046597-&&-negative regulation of viral entry into host cell-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0030992-&&-intraciliary transport particle B-%%-GO:0005929-&&-cilium-%%-GO:0005813-&&-centrosome-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:TRIM59				TRIM59	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM59	0.35992968	0.2	5	4	FALSE	TRIM59	TRIM59	389.2	0	5	0	0.70361326	FALSE	0	TRIM59	4320	0.24483627
788662	taxon:9606	3.63730896	2.50E-06	177233	1902	thrombomodulin	gene	biological_process-&-1&-GO:0051918-&&-negative regulation of fibrinolysis-%%-GO:0050900-&&-leukocyte migration-%%-GO:0010544-&&-negative regulation of platelet activation-%%-GO:0007565-&&-female pregnancy-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007165-&&-signal transduction-%%-GO:0051591-&&-response to cAMP-%%-GO:0007596-&&-blood coagulation-%%-GO:0030195-&&-negative regulation of blood coagulation-%%-GO:0010165-&&-response to X-ray|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005774-&&-vacuolar membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016327-&&-apicolateral plasma membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:THBD	THBD	TRUE	KEGG-&-1&-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa04610-&&-Complement and coagulation cascades	THBD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THBD	0.27492853	0.4	5	5	FALSE	THBD	THBD	15.4	0	5	0	0.56044851	FALSE	0	THBD	1486	0.25762712
788665	taxon:9606	3.60753112	1.51E-06	177231	1902	thrombospondin 2	gene	biological_process-&-1&-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0007155-&&-cell adhesion-%%-GO:0051965-&&-positive regulation of synapse assembly|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005604-&&-basement membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0031091-&&-platelet alpha granule|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:THBS2			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04145-&&-Phagosome-%%-hsa04510-&&-Focal adhesion-%%-hsa05144-&&-Malaria-%%-hsa05165-&&-Human papillomavirus infection	THBS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THBS2	0.27719789	0	5	5	FALSE	THBS2	THBS2	39	0	4	0	0.56541148	FALSE	1	THBS2	1030	0.37254902
788703	taxon:9606	3.27824169	3.34E-06	177154	1902	tenascin XB	gene	biological_process-&-1&-GO:0032963-&&-collagen metabolic process-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0048251-&&-elastic fiber assembly-%%-GO:0030036-&&-actin cytoskeleton organization|cellular_component-&-1&-GO:0005583-&&-fibrillar collagen trimer-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0005178-&&-integrin binding-%%-GO:0005515-&&-protein binding	G:9606:TNXB	TNXB	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04510-&&-Focal adhesion-%%-hsa05165-&&-Human papillomavirus infection	TNXB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNXB	0.30504157	0.1	5	5	FALSE	TNXB	TNXB	31.2	0	5	0	0.62029305	FALSE	0	TNXB	2708	0.2125
788764	taxon:9606	3.39766819	7.33E-06	160603	1902	metaxin 3	gene	biological_process-&-1&-GO:0006626-&&-protein targeting to mitochondrion|cellular_component-&-1&-GO:0005741-&&-mitochondrial outer membrane	G:9606:MTX3				MTX3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTX3	0.2943195	0	5	5	FALSE	MTX3	MTX3	32	0	5	0	0.60038864	FALSE	0	MTX3	4878	0.20805369
788782	taxon:9606	3.10414369	3.83E-06	176915	1902	mal, T-cell differentiation protein like	gene	biological_process-&-1&-GO:0008104-&&-protein localization-%%-GO:0001766-&&-membrane raft polarization-%%-GO:0042552-&&-myelination-%%-GO:0042632-&&-cholesterol homeostasis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0030136-&&-clathrin-coated vesicle-%%-GO:0045121-&&-membrane raft-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0019911-&&-structural constituent of myelin sheath-%%-GO:0005515-&&-protein binding	G:9606:MALL				MALL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MALL	0.32215004	0.1	5	5	FALSE	MALL	MALL	66.2	0	5	0	0.64930939	FALSE	0	MALL	3038	0.21437908
788888	taxon:9606	3.04962975	3.28E-06	176668	1902	X-linked Kx blood group	gene	biological_process-&-1&-GO:0048741-&&-skeletal muscle fiber development-%%-GO:0008361-&&-regulation of cell size-%%-GO:0010961-&&-cellular magnesium ion homeostasis-%%-GO:0031133-&&-regulation of axon diameter-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0006865-&&-amino acid transport-%%-GO:0006810-&&-transport-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005515-&&-protein binding	G:9606:XK				XK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XK	0.32790866	0.1	5	5	FALSE	XK	XK	83.8	0	5	0	0.65839504	FALSE	0	XK	2226	0.21278772
788914	taxon:9606	2.86418781	7.21E-06	176604	1902	SPARC like 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0048856-&&-anatomical structure development|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005518-&&-collagen binding-%%-GO:0050840-&&-extracellular matrix binding	G:9606:SPARCL1				SPARCL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPARCL1	0.34913912	0	5	4	FALSE	SPARCL1	SPARCL1	233.2	0	5	0	0.68930203	FALSE	0	SPARCL1	9914	0.20862534
788970	taxon:9606	2.99464314	1.55E-06	176508	1902	zinc finger protein 7	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF7				ZNF7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF7	0.3339296	0	5	5	FALSE	ZNF7	ZNF7	110.8	0	5	0	0.66755948	FALSE	0	ZNF7	1660	0.20874525
789051	taxon:9606	2.87915551	4.18E-06	176286	1902	regulator of G-protein signaling 11	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0031681-&&-G-protein beta-subunit binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005096-&&-GTPase activator activity	G:9606:RGS11				RGS11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS11	0.34732407	0.1	5	5	FALSE	RGS11	RGS11	241	0	5	0	0.68680742	FALSE	0	RGS11	7558	0.23708087
789153	taxon:9606	2.96470774	8.00E-08	159705	1902	ring finger protein 207	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:1901207-&&-regulation of heart looping-%%-GO:0055117-&&-regulation of cardiac muscle contraction-%%-GO:1902261-&&-positive regulation of delayed rectifier potassium channel activity-%%-GO:1903954-&&-positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization-%%-GO:1903762-&&-positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0086019-&&-cell-cell signaling involved in cardiac conduction|cellular_component-&-1&-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0051087-&&-chaperone binding-%%-GO:0044325-&&-ion channel binding-%%-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005515-&&-protein binding	G:9606:RNF207				RNF207	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF207	0.33730138	0.7	5	5	FALSE	RNF207	RNF207	195.2	0	5	0	0.67254871	FALSE	0	RNF207	206	0.36691729
789169	taxon:9606	3.07846227	4.60E-07	176058	1902	regucalcin	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0097421-&&-liver regeneration-%%-GO:1903011-&&-negative regulation of bone development-%%-GO:2000279-&&-negative regulation of DNA biosynthetic process-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:1901318-&&-negative regulation of flagellated sperm motility-%%-GO:1901671-&&-positive regulation of superoxide dismutase activity-%%-GO:0010907-&&-positive regulation of glucose metabolic process-%%-GO:0010867-&&-positive regulation of triglyceride biosynthetic process-%%-GO:0045723-&&-positive regulation of fatty acid biosynthetic process-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0010922-&&-positive regulation of phosphatase activity-%%-GO:0019853-&&-L-ascorbic acid biosynthetic process-%%-GO:0001822-&&-kidney development-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0051344-&&-negative regulation of cyclic-nucleotide phosphodiesterase activity-%%-GO:0007568-&&-aging-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:1903611-&&-negative regulation of calcium-dependent ATPase activity-%%-GO:1902679-&&-negative regulation of RNA biosynthetic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0034260-&&-negative regulation of GTPase activity-%%-GO:1903629-&&-positive regulation of dUTP diphosphatase activity-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:1903052-&&-positive regulation of proteolysis involved in cellular protein catabolic process-%%-GO:1903625-&&-negative regulation of DNA catabolic process-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:1903634-&&-negative regulation of leucine-tRNA ligase activity-%%-GO:1901896-&&-positive regulation of calcium-transporting ATPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0030234-&&-enzyme regulator activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004341-&&-gluconolactonase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:RGN			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa01200-&&-Carbon metabolism-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00030-&&-Pentose phosphate pathway	RGN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGN	0.3248375	0.3	5	5	FALSE	RGN	RGN	98.8	0	5	0	0.65358962	FALSE	0	RGN	762	0.25811518
789313	taxon:9606	2.96045376	7.17E-06	175765	1902	napsin A aspartic peptidase	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0030163-&&-protein catabolic process-%%-GO:0006914-&&-autophagy-%%-GO:0033619-&&-membrane protein proteolysis-%%-GO:0043129-&&-surfactant homeostasis|cellular_component-&-1&-GO:0097486-&&-multivesicular body lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0097208-&&-alveolar lamellar body-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0008233-&&-peptidase activity-%%-GO:0004175-&&-endopeptidase activity-%%-GO:0004190-&&-aspartic-type endopeptidase activity	G:9606:NAPSA			KEGG-&-1&-hsa04142-&&-Lysosome	NAPSA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAPSA	0.33778606	0	5	5	FALSE	NAPSA	NAPSA	130.8	0	5	0	0.67325771	FALSE	0	NAPSA	7688	0.20768
789346	taxon:9606	2.9220104	6.00E-08	175689	1902	potassium voltage-gated channel subfamily Q member 4	gene	biological_process-&-1&-GO:0007605-&&-sensory perception of sound-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009925-&&-basal plasma membrane|molecular_function-&-1&-GO:0005267-&&-potassium channel activity-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0005515-&&-protein binding	G:9606:KCNQ4			KEGG-&-1&-hsa04725-&&-Cholinergic synapse	KCNQ4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNQ4	0.34223013	0.3	5	5	FALSE	KCNQ4	KCNQ4	209	0	5	0	0.67966493	FALSE	0	KCNQ4	258	0.27765957
789412	taxon:9606	3.36678746	3.36E-06	175536	1902	beta-1,4-galactosyltransferase 5	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing-%%-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032580-&&-Golgi cisterna membrane|molecular_function-&-1&-GO:0003831-&&-beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0008378-&&-galactosyltransferase activity	G:9606:B4GALT5			KEGG-&-1&-hsa00512-&&-Mucin type O-glycan biosynthesis-%%-hsa01100-&&-Metabolic pathways	B4GALT5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-B4GALT5	0.29701905	0	5	5	FALSE	B4GALT5	B4GALT5	42.2	0	5	0	0.60553542	FALSE	0	B4GALT5	2452	0.22391304
789413	taxon:9606	2.94627383	3.01E-06	175538	1902	CD163 molecule	gene	biological_process-&-1&-GO:0006953-&&-acute-phase response-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0030666-&&-endocytic vesicle membrane|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity-%%-GO:0005515-&&-protein binding	G:9606:CD163				CD163	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD163	0.33941176	0	5	5	FALSE	CD163	CD163	160.2	0	5	0	0.67562103	FALSE	0	CD163	3410	0.21958621
789569	taxon:9606	2.77233339	3.20E-07	158776	1902	SHC adaptor protein 4	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0006915-&&-apoptotic process-%%-GO:0048863-&&-stem cell differentiation|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0019904-&&-protein domain specific binding-%%-GO:0030971-&&-receptor tyrosine kinase binding-%%-GO:0005515-&&-protein binding	G:9606:SHC4			KEGG-&-1&-hsa04722-&&-Neurotrophin signaling pathway-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa05214-&&-Glioma-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa01522-&&-Endocrine resistance-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05220-&&-Chronic myeloid leukemia-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance-%%-hsa04926-&&-Relaxin signaling pathway-%%-hsa04917-&&-Prolactin signaling pathway-%%-hsa05034-&&-Alcoholism-%%-hsa04510-&&-Focal adhesion-%%-hsa05100-&&-Bacterial invasion of epithelial cells-%%-hsa04915-&&-Estrogen signaling pathway-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	SHC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHC4	0.36070698	0.6	5	5	FALSE	SHC4	SHC4	407.4	0	5	0	0.7046111	FALSE	0	SHC4	1570	0.25833862
789583	taxon:9606	2.75547503	1.20E-07	175134	1902	Rho related BTB domain containing 1	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding	G:9606:RHOBTB1			KEGG-&-1&-hsa04120-&&-Ubiquitin mediated proteolysis	RHOBTB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHOBTB1	0.36291383	0.8	5	4	FALSE	RHOBTB1	RHOBTB1	543.8	0	5	0	0.70742083	FALSE	0	RHOBTB1	874	0.3167152
789669	taxon:9606	2.73735623	4.61E-06	174933	1902	olfactomedin 1	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition-%%-GO:0030516-&&-regulation of axon extension-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:0023041-&&-neuronal signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0003190-&&-atrioventricular valve formation-%%-GO:0060317-&&-cardiac epithelial to mesenchymal transition|cellular_component-&-1&-GO:0005623-&&-cell-%%-GO:0044295-&&-axonal growth cone-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0043025-&&-neuronal cell body-%%-GO:0045202-&&-synapse-%%-GO:0030424-&&-axon-%%-GO:0030054-&&-cell junction-%%-GO:0005615-&&-extracellular space-%%-GO:0043204-&&-perikaryon|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:OLFM1				OLFM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OLFM1	0.36531599	0.3	5	5	FALSE	OLFM1	OLFM1	405.8	0	5	0	0.71044063	FALSE	0	OLFM1	5736	0.22508324
789798	taxon:9606	3.14542303	1.60E-06	174640	1902	Rab9 effector protein with kelch motifs	gene	biological_process-&-1&-GO:0006904-&&-vesicle docking involved in exocytosis-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0030133-&&-transport vesicle-%%-GO:0005829-&&-cytosol-%%-GO:0010008-&&-endosome membrane-%%-GO:0005768-&&-endosome-%%-GO:0032588-&&-trans-Golgi network membrane	G:9606:RABEPK				RABEPK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RABEPK	0.31792226	0	5	5	FALSE	RABEPK	RABEPK	45.8	0	5	0	0.64242949	FALSE	0	RABEPK	1078	0.20645161
789897	taxon:9606	2.89160233	1.08E-06	158020	1902	TBC1 domain family member 3B	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0006886-&&-intracellular protein transport-%%-GO:0090630-&&-activation of GTPase activity|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D3B				TBC1D3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D3B	0.34582902	0.1	5	5	FALSE	TBC1D3B	TBC1D3B	227	0	5	0	0.68473294	FALSE	0	TBC1D3B	2618	0.23881857
789956	taxon:9606	3.58295258	1.68E-06	157864	1902	C-C motif chemokine ligand 3 like 3	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL3L3			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05142-&&-Chagas disease (American trypanosomiasis)-%%-hsa05132-&&-Salmonella infection-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05323-&&-Rheumatoid arthritis	CCL3L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL3L3	0.27909942	0	5	5	FALSE	CCL3L3	CCL3L3	24	0	5	0	0.5695079	FALSE	0	CCL3L3	2124	0.30666667
790005	taxon:9606	3.03765559	1.52E-06	174134	1902	ankyrin repeat domain 6	gene	biological_process-&-1&-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:2000096-&&-positive regulation of Wnt signaling pathway, planar cell polarity pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0043231-&&-intracellular membrane-bounded organelle	G:9606:ANKRD6				ANKRD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD6	0.32920124	0.4	5	5	FALSE	ANKRD6	ANKRD6	125.2	0	5	0	0.66039074	FALSE	0	ANKRD6	1618	0.26709402
790034	taxon:9606	2.96754372	7.79E-06	174048	1902	chondromodulin	gene	biological_process-&-1&-GO:0006029-&&-proteoglycan metabolic process-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0051216-&&-cartilage development-%%-GO:0001501-&&-skeletal system development-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0012505-&&-endomembrane system	G:9606:CNMD				CNMD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CNMD	0.33697903	0	5	4	FALSE	CNMD	CNMD	137.6	0	5	0	0.67207605	FALSE	0	CNMD	4704	0.20297177
790046	taxon:9606	2.93288168	8.20E-07	174014	1902	arginyltransferase 1	gene	biological_process-&-1&-GO:0016598-&&-protein arginylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004057-&&-arginyltransferase activity	G:9606:ATE1				ATE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATE1	0.34096159	0	5	5	FALSE	ATE1	ATE1	167.2	0	5	0	0.67785305	FALSE	0	ATE1	1524	0.21612484
790076	taxon:9606	2.97857255	2.70E-07	173938	1902	CUGBP Elav-like family member 3	gene	biological_process-&-1&-GO:0048026-&&-positive regulation of mRNA splicing, via spliceosome-%%-GO:0030317-&&-flagellated sperm motility-%%-GO:0000381-&&-regulation of alternative mRNA splicing, via spliceosome-%%-GO:0000398-&&-mRNA splicing, via spliceosome-%%-GO:0007283-&&-spermatogenesis-%%-GO:0008380-&&-RNA splicing-%%-GO:0030575-&&-nuclear body organization-%%-GO:0098781-&&-ncRNA transcription|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0016604-&&-nuclear body|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0097322-&&-7SK snRNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0003729-&&-mRNA binding	G:9606:CELF3				CELF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CELF3	0.33573129	0.4	5	5	FALSE	CELF3	CELF3	139.4	0	5	0	0.67023791	FALSE	0	CELF3	648	0.24672566
790338	taxon:9606	2.88860879	1.00E-07	173291	1902	RWD domain containing 3	gene	biological_process-&-1&-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0033235-&&-positive regulation of protein sumoylation-%%-GO:1902073-&&-positive regulation of hypoxia-inducible factor-1alpha signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RWDD3				RWDD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RWDD3	0.34618741	0.6	5	5	FALSE	RWDD3	RWDD3	253	0	5	0	0.68523187	FALSE	0	RWDD3	450	0.25975359
790495	taxon:9606	2.95320624	3.50E-07	156310	1902	family with sequence similarity 110 member C	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060491-&&-regulation of cell projection assembly|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005938-&&-cell cortex-%%-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0043014-&&-alpha-tubulin binding-%%-GO:0005515-&&-protein binding	G:9606:FAM110C				FAM110C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM110C	0.33861502	0.3	5	5	FALSE	FAM110C	FAM110C	162.2	0	5	0	0.67446563	FALSE	0	FAM110C	960	0.25910543
790523	taxon:9606	2.81377029	1.08E-05	172611	1902	nicotinamide riboside kinase 2	gene	biological_process-&-1&-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0009435-&&-NAD biosynthetic process-%%-GO:0016310-&&-phosphorylation-%%-GO:0019674-&&-NAD metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0061769-&&-ribosylnicotinate kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0050262-&&-ribosylnicotinamide kinase activity-%%-GO:0005515-&&-protein binding	G:9606:NMRK2			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	NMRK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NMRK2	0.35539504	0.1	5	5	FALSE	NMRK2	NMRK2	290.8	0	5	0	0.69770495	FALSE	0	NMRK2	10636	0.21640567
790576	taxon:9606	3.27446037	2.87E-06	172089	1902	growth hormone inducible transmembrane protein	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:GHITM				GHITM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GHITM	0.30539383	0.1	5	5	FALSE	GHITM	GHITM	51	0	5	0	0.62092327	FALSE	0	GHITM	1754	0.22300885
790711	taxon:9606	3.15645187	2.80E-06	171408	1902	UbiA prenyltransferase domain containing 1	gene	biological_process-&-1&-GO:0042371-&&-vitamin K biosynthetic process-%%-GO:0042373-&&-vitamin K metabolic process-%%-GO:0032194-&&-ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0006744-&&-ubiquinone biosynthetic process-%%-GO:0009234-&&-menaquinone biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0030173-&&-integral component of Golgi membrane-%%-GO:0016020-&&-membrane-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004659-&&-prenyltransferase activity-%%-GO:0016209-&&-antioxidant activity	G:9606:UBIAD1				UBIAD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UBIAD1	0.31681142	0	5	5	FALSE	UBIAD1	UBIAD1	84.8	0	5	0	0.64059136	FALSE	0	UBIAD1	2664	0.26024845
790719	taxon:9606	2.761147	3.91E-06	171393	1902	THAP domain containing 4	gene	molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:THAP4				THAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THAP4	0.36216833	0.1	5	5	FALSE	THAP4	THAP4	370.2	0	5	0	0.7064755	FALSE	0	THAP4	7702	0.22427184
790721	taxon:9606	3.02253033	9.00E-08	171385	1902	Y-box binding protein 2	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0009386-&&-translational attenuation-%%-GO:0048599-&&-oocyte development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007283-&&-spermatogenesis|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0001650-&&-fibrillar center|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding	G:9606:YBX2				YBX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YBX2	0.33084862	0.4	5	5	FALSE	YBX2	YBX2	162.8	0	5	0	0.66291161	FALSE	0	YBX2	412	0.29509982
790763	taxon:9606	3.00724752	9.40E-07	171293	1902	phospholipase C epsilon 1	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0006940-&&-regulation of smooth muscle contraction-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0032835-&&-glomerulus development-%%-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0048016-&&-inositol phosphate-mediated signaling-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0008283-&&-cell proliferation-%%-GO:0016042-&&-lipid catabolic process-%%-GO:0046578-&&-regulation of Ras protein signal transduction-%%-GO:0045859-&&-regulation of protein kinase activity-%%-GO:0006651-&&-diacylglycerol biosynthetic process-%%-GO:0007205-&&-protein kinase C-activating G-protein coupled receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0007265-&&-Ras protein signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0007010-&&-cytoskeleton organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005057-&&-signal transducer activity, downstream of receptor-%%-GO:0017016-&&-Ras GTPase binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity-%%-GO:0005085-&&-guanyl-nucleotide exchange factor activity-%%-GO:0004629-&&-phospholipase C activity	G:9606:PLCE1			KEGG-&-1&-hsa04919-&&-Thyroid hormone signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04024-&&-cAMP signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa00562-&&-Inositol phosphate metabolism	PLCE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCE1	0.33252999	0.1	5	5	FALSE	PLCE1	PLCE1	122.8	0	5	0	0.66545875	FALSE	0	PLCE1	1450	0.22463235
790845	taxon:9606	3.06664566	4.16E-06	154580	1902	defensin alpha 1B	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045087-&&-innate immune response-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0050832-&&-defense response to fungus-%%-GO:0006955-&&-immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0031640-&&-killing of cells of other organism-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region	G:9606:DEFA1B			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05150-&&-Staphylococcus aureus infection	DEFA1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEFA1B	0.32608919	0	5	5	FALSE	DEFA1B	DEFA1B	82	0	5	0	0.65555906	FALSE	0	DEFA1B	2836	0.20716113
791000	taxon:9606	3.02142745	5.50E-07	170453	1902	Sec61 translocon alpha 2 subunit	gene	biological_process-&-1&-GO:0015031-&&-protein transport-%%-GO:0008150-&&-biological_process-%%-GO:0036498-&&-IRE1-mediated unfolded protein response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0043022-&&-ribosome binding	G:9606:SEC61A2			KEGG-&-1&-hsa03060-&&-Protein export-%%-hsa04145-&&-Phagosome-%%-hsa05110-&&-Vibrio cholerae infection-%%-hsa04141-&&-Protein processing in endoplasmic reticulum	SEC61A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC61A2	0.33096939	0.2	5	5	FALSE	SEC61A2	SEC61A2	97.2	0	5	0	0.66309543	FALSE	0	SEC61A2	958	0.22716628
791025	taxon:9606	2.85520718	1.22E-06	170330	1902	SNF related kinase	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0030099-&&-myeloid cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0000287-&&-magnesium ion binding	G:9606:SNRK				SNRK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SNRK	0.35023728	0.1	5	4	FALSE	SNRK	SNRK	257.2	0	5	0	0.6907988	FALSE	0	SNRK	2642	0.2212069
791145	taxon:9606	2.75957145	2.70E-05	169891	1902	zinc finger DHHC-type containing 7	gene	biological_process-&-1&-GO:0018230-&&-peptidyl-L-cysteine S-palmitoylation-%%-GO:0018345-&&-protein palmitoylation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016409-&&-palmitoyltransferase activity-%%-GO:0019706-&&-protein-cysteine S-palmitoyltransferase activity	G:9606:ZDHHC7				ZDHHC7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZDHHC7	0.36237511	0	5	5	FALSE	ZDHHC7	ZDHHC7	359.2	0	5	0	0.70673809	FALSE	0	ZDHHC7	14496	0.21841463
791166	taxon:9606	3.08760044	8.60E-07	169843	1902	melanoregulin	gene	biological_process-&-1&-GO:0032402-&&-melanosome transport-%%-GO:0030318-&&-melanocyte differentiation|cellular_component-&-1&-GO:0042470-&&-melanosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0043234-&&-protein complex	G:9606:MREG				MREG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MREG	0.3238761	0	5	5	FALSE	MREG	MREG	60.8	0	5	0	0.65206659	FALSE	0	MREG	964	0.21205674
791191	taxon:9606	2.91019379	6.20E-07	169786	1902	oxoglutarate dehydrogenase-like	gene	biological_process-&-1&-GO:0006099-&&-tricarboxylic acid cycle-%%-GO:0006096-&&-glycolytic process|cellular_component-&-1&-GO:0005739-&&-mitochondrion-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0045252-&&-oxoglutarate dehydrogenase complex|molecular_function-&-1&-GO:0004591-&&-oxoglutarate dehydrogenase (succinyl-transferring) activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0030976-&&-thiamine pyrophosphate binding-%%-GO:0005515-&&-protein binding	G:9606:OGDHL			KEGG-&-1&-hsa00020-&&-Citrate cycle (TCA cycle)-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00310-&&-Lysine degradation	OGDHL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OGDHL	0.34361973	0.2	5	5	FALSE	OGDHL	OGDHL	187.6	0	5	0	0.68163437	FALSE	0	OGDHL	1560	0.23111111
791202	taxon:9606	2.90499449	9.70E-07	169733	1902	B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB	gene	biological_process-&-1&-GO:0070898-&&-RNA polymerase III transcriptional preinitiation complex assembly-%%-GO:0006359-&&-regulation of transcription from RNA polymerase III promoter|cellular_component-&-1&-GO:0000126-&&-transcription factor TFIIIB complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0001026-&&-TFIIIB-type transcription factor activity-%%-GO:0003677-&&-DNA binding-%%-GO:0001156-&&-TFIIIC-class transcription factor binding	G:9606:BDP1				BDP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BDP1	0.34423473	0.1	5	5	FALSE	BDP1	BDP1	192.6	0	5	0	0.68250092	FALSE	0	BDP1	1652	0.22668241
791234	taxon:9606	3.03214117	9.00E-07	169588	1902	NSE3 homolog, SMC5-SMC6 complex component	gene	biological_process-&-1&-GO:0040008-&&-regulation of growth-%%-GO:0006310-&&-DNA recombination-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:0006281-&&-DNA repair|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0000781-&&-chromosome, telomeric region-%%-GO:0030915-&&-Smc5-Smc6 complex-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:NSMCE3				NSMCE3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NSMCE3	0.32979995	0.1	5	5	FALSE	NSMCE3	NSMCE3	85.4	0	5	0	0.66130981	FALSE	0	NSMCE3	1108	0.22315789
791280	taxon:9606	2.90798803	9.70E-07	169387	1902	zinc finger protein 398	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF398				ZNF398	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF398	0.34388037	0	5	5	FALSE	ZNF398	ZNF398	191.4	0	5	0	0.682002	FALSE	0	ZNF398	2074	0.21297539
791294	taxon:9606	2.7726485	4.77E-06	169305	1902	pogo transposable element with KRAB domain	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0005515-&&-protein binding	G:9606:POGK				POGK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POGK	0.36066598	0.1	5	5	FALSE	POGK	POGK	352	0	5	0	0.70455858	FALSE	0	POGK	7562	0.22268695
791302	taxon:9606	2.83409485	5.25E-06	169287	1902	transmembrane 9 superfamily member 3	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TM9SF3				TM9SF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TM9SF3	0.35284634	0.2	5	4	FALSE	TM9SF3	TM9SF3	305.4	0	5	0	0.69431753	FALSE	0	TM9SF3	9448	0.23787997
791323	taxon:9606	2.8523712	9.40E-07	169171	1902	tripartite motif containing 49	gene	cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:TRIM49				TRIM49	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM49	0.35058551	0.5	5	5	FALSE	TRIM49	TRIM49	279.8	0	5	0	0.69127147	FALSE	0	TRIM49	1198	0.233
791349	taxon:9606	3.08854577	1.27E-06	169057	1902	pappalysin 2	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0006508-&&-proteolysis-%%-GO:0060349-&&-bone morphogenesis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008237-&&-metallopeptidase activity	G:9606:PAPPA2				PAPPA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAPPA2	0.32377697	0.1	5	5	FALSE	PAPPA2	PAPPA2	77	0	5	0	0.65190904	FALSE	0	PAPPA2	1376	0.21766382
791352	taxon:9606	2.8290531	1.01E-06	169045	1902	serine racemase	gene	biological_process-&-1&-GO:0070179-&&-D-serine biosynthetic process-%%-GO:0042866-&&-pyruvate biosynthetic process-%%-GO:0007420-&&-brain development-%%-GO:0006563-&&-L-serine metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0051289-&&-protein homotetramerization-%%-GO:0043278-&&-response to morphine-%%-GO:0007568-&&-aging-%%-GO:0009069-&&-serine family amino acid metabolic process-%%-GO:0070178-&&-D-serine metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0045177-&&-apical part of cell-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0030165-&&-PDZ domain binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0005524-&&-ATP binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0000287-&&-magnesium ion binding-%%-GO:0030378-&&-serine racemase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0018114-&&-threonine racemase activity-%%-GO:0016594-&&-glycine binding-%%-GO:0008721-&&-D-serine ammonia-lyase activity-%%-GO:0003941-&&-L-serine ammonia-lyase activity	G:9606:SRR			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00260-&&-Glycine, serine and threonine metabolism	SRR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRR	0.35347516	0.33333333	5	5	FALSE	SRR	SRR	454.6666667	0	4	0	0.69515782	FALSE	1	SRR	1376	0.35494792
791398	taxon:9606	3.04395778	5.19E-06	168807	1902	netrin 4	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:0016322-&&-neuron remodeling-%%-GO:0060668-&&-regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0043237-&&-laminin-1 binding-%%-GO:0005515-&&-protein binding	G:9606:NTN4			KEGG-&-1&-hsa04360-&&-Axon guidance	NTN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NTN4	0.32851967	0.1	5	5	FALSE	NTN4	NTN4	87.8	0	5	0	0.65934037	FALSE	0	NTN4	3326	0.21165049
791403	taxon:9606	2.83756105	2.20E-07	168772	1902	methenyltetrahydrofolate synthetase domain containing	gene	biological_process-&-1&-GO:0008298-&&-intracellular mRNA localization|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:MTHFSD				MTHFSD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTHFSD	0.35241532	0.3	5	4	FALSE	MTHFSD	MTHFSD	335.2	0	5	0	0.69373982	FALSE	0	MTHFSD	1006	0.25674847
791430	taxon:9606	2.90940602	1.42E-06	168679	1902	neurobeachin like 1	gene		G:9606:NBEAL1				NBEAL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBEAL1	0.34371277	0.1	5	5	FALSE	NBEAL1	NBEAL1	218.2	0	5	0	0.68176566	FALSE	0	NBEAL1	1874	0.24421998
791444	taxon:9606	3.12525603	4.17E-06	168608	1902	collectin subfamily member 11	gene	biological_process-&-1&-GO:0032502-&&-developmental process-%%-GO:0006956-&&-complement activation-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006508-&&-proteolysis-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005581-&&-collagen trimer|molecular_function-&-1&-GO:0005537-&&-mannose binding-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:COLEC11	COLEC11	TRUE	KEGG-&-1&-hsa04145-&&-Phagosome	COLEC11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COLEC11	0.31997379	0	5	5	FALSE	COLEC11	COLEC11	54.4	0	5	0	0.64579066	FALSE	0	COLEC11	6132	0.21190476
791476	taxon:9606	2.8756893	1.16E-06	168479	1902	tRNA methyltransferase 11 homolog	gene	biological_process-&-1&-GO:0030488-&&-tRNA methylation|molecular_function-&-1&-GO:0004809-&&-tRNA (guanine-N2-)-methyltransferase activity-%%-GO:0000049-&&-tRNA binding	G:9606:TRMT11				TRMT11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRMT11	0.34774271	0.4	5	4	FALSE	TRMT11	TRMT11	258.2	0	5	0	0.68738512	FALSE	0	TRMT11	1714	0.23561644
791572	taxon:9606	2.9933827	1.12E-06	167962	1902	asparaginase like 1	gene	biological_process-&-1&-GO:0033345-&&-asparagine catabolic process via L-aspartate-%%-GO:0006508-&&-proteolysis-%%-GO:0006559-&&-L-phenylalanine catabolic process|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004067-&&-asparaginase activity-%%-GO:0008798-&&-beta-aspartyl-peptidase activity-%%-GO:0003948-&&-N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	G:9606:ASRGL1				ASRGL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASRGL1	0.33407021	0.1	5	5	FALSE	ASRGL1	ASRGL1	106.4	0	5	0	0.66776955	FALSE	0	ASRGL1	1306	0.21547862
791725	taxon:9606	2.71876477	2.78E-06	167181	1902	SH3 domain binding glutamate rich protein like 3	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0043535-&&-regulation of blood vessel endothelial cell migration-%%-GO:0030834-&&-regulation of actin filament depolymerization-%%-GO:0045454-&&-cell redox homeostasis|cellular_component-&-1&-GO:0030027-&&-lamellipodium-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016604-&&-nuclear body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0015035-&&-protein disulfide oxidoreductase activity-%%-GO:0030215-&&-semaphorin receptor binding	G:9606:SH3BGRL3				SH3BGRL3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3BGRL3	0.36781409	0.2	5	4	FALSE	SH3BGRL3	SH3BGRL3	454.6	0	5	0	0.7135392	FALSE	0	SH3BGRL3	4296	0.23880126
791769	taxon:9606	2.94501339	2.94E-06	166959	1902	zinc and ring finger 3	gene	biological_process-&-1&-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0072089-&&-stem cell proliferation-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:2000051-&&-negative regulation of non-canonical Wnt signaling pathway-%%-GO:0038018-&&-Wnt receptor catabolic process-%%-GO:0060070-&&-canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005109-&&-frizzled binding	G:9606:ZNRF3			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway	ZNRF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNRF3	0.33955703	0.2	5	5	FALSE	ZNRF3	ZNRF3	159.4	0	5	0	0.6758311	FALSE	0	ZNRF3	1976	0.21689373
791782	taxon:9606	2.92468883	4.90E-07	166885	1902	FLYWCH-type zinc finger 1	gene	cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:FLYWCH1				FLYWCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FLYWCH1	0.34191672	0	5	5	FALSE	FLYWCH1	FLYWCH1	189.4	0	5	0	0.67921853	FALSE	0	FLYWCH1	1650	0.23059976
791806	taxon:9606	2.96880416	5.00E-07	166781	1902	mitogen-activated protein kinase kinase kinase 21	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation-%%-GO:0007257-&&-activation of JUN kinase activity-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007256-&&-activation of JNKK activity|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0005524-&&-ATP binding-%%-GO:0004706-&&-JUN kinase kinase kinase activity-%%-GO:0005515-&&-protein binding	G:9606:MAP3K21				MAP3K21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K21	0.33683596	0.2	5	5	FALSE	MAP3K21	MAP3K21	144.2	0	5	0	0.67186597	FALSE	0	MAP3K21	916	0.2513986
792013	taxon:9606	3.19662833	4.59E-06	182729	1902	bone gamma-carboxyglutamate protein	gene	biological_process-&-1&-GO:0014823-&&-response to activity-%%-GO:0060348-&&-bone development-%%-GO:0033574-&&-response to testosterone-%%-GO:0043627-&&-response to estrogen-%%-GO:0002076-&&-osteoblast development-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0010043-&&-response to zinc ion-%%-GO:0033280-&&-response to vitamin D-%%-GO:0032571-&&-response to vitamin K-%%-GO:0030282-&&-bone mineralization-%%-GO:0071305-&&-cellular response to vitamin D-%%-GO:0042476-&&-odontogenesis-%%-GO:0045471-&&-response to ethanol-%%-GO:0001501-&&-skeletal system development-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007569-&&-cell aging-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0006465-&&-signal peptide processing-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0009629-&&-response to gravity-%%-GO:0030500-&&-regulation of bone mineralization-%%-GO:0017187-&&-peptidyl-glutamic acid carboxylation-%%-GO:0042493-&&-response to drug-%%-GO:0045124-&&-regulation of bone resorption-%%-GO:0007155-&&-cell adhesion-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0033594-&&-response to hydroxyisoflavone-%%-GO:0045670-&&-regulation of osteoclast differentiation|cellular_component-&-1&-GO:0031982-&&-vesicle-%%-GO:0005796-&&-Golgi lumen-%%-GO:0043204-&&-perikaryon-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005615-&&-extracellular space-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005791-&&-rough endoplasmic reticulum|molecular_function-&-1&-GO:0008147-&&-structural constituent of bone-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0046848-&&-hydroxyapatite binding	G:9606:BGLAP	BGLAP	TRUE	KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	BGLAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BGLAP	0.31282961	0.1	5	5	FALSE	BGLAP	BGLAP	51.8	0	5	0	0.63389528	FALSE	0	BGLAP	5432	0.21157025
792121	taxon:9606	2.95100047	5.96E-06	166186	1902	heparan sulfate 6-O-sulfotransferase 2	gene	biological_process-&-1&-GO:0015015-&&-heparan sulfate proteoglycan biosynthetic process, enzymatic modification-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0017095-&&-heparan sulfate 6-O-sulfotransferase activity	G:9606:HS6ST2			KEGG-&-1&-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	HS6ST2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HS6ST2	0.33886813	0	5	5	FALSE	HS6ST2	HS6ST2	138	0	5	0	0.67483325	FALSE	0	HS6ST2	6230	0.20789074
792347	taxon:9606	2.7910824	1.47E-06	165796	1902	topoisomerase (DNA) I, mitochondrial	gene	biological_process-&-1&-GO:0006265-&&-DNA topological change-%%-GO:0007059-&&-chromosome segregation-%%-GO:0006338-&&-chromatin remodeling-%%-GO:0006260-&&-DNA replication|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005730-&&-nucleolus-%%-GO:0042645-&&-mitochondrial nucleoid-%%-GO:0031298-&&-replication fork protection complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003917-&&-DNA topoisomerase type I activity-%%-GO:0003677-&&-DNA binding	G:9606:TOP1MT				TOP1MT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOP1MT	0.35828394	0.1	5	4	FALSE	TOP1MT	TOP1MT	380.6	0	5	0	0.70148627	FALSE	0	TOP1MT	2758	0.24707412
792348	taxon:9606	2.79628171	7.04E-06	182183	1902	cholinergic receptor nicotinic alpha 7 subunit	gene	biological_process-&-1&-GO:0050808-&&-synapse organization-%%-GO:0006816-&&-calcium ion transport-%%-GO:1901214-&&-regulation of neuron death-%%-GO:0095500-&&-acetylcholine receptor signaling pathway-%%-GO:0050893-&&-sensory processing-%%-GO:0007613-&&-memory-%%-GO:1904645-&&-response to beta-amyloid-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0007614-&&-short-term memory-%%-GO:0032720-&&-negative regulation of tumor necrosis factor production-%%-GO:1905144-&&-response to acetylcholine-%%-GO:0050890-&&-cognition-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0060291-&&-long-term synaptic potentiation-%%-GO:1902430-&&-negative regulation of beta-amyloid formation-%%-GO:1905906-&&-regulation of amyloid fibril formation-%%-GO:2000463-&&-positive regulation of excitatory postsynaptic potential-%%-GO:0048813-&&-dendrite morphogenesis-%%-GO:0035094-&&-response to nicotine-%%-GO:0006874-&&-cellular calcium ion homeostasis-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0007611-&&-learning or memory-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:1902004-&&-positive regulation of beta-amyloid formation-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:1902991-&&-regulation of amyloid precursor protein catabolic process-%%-GO:0051247-&&-positive regulation of protein metabolic process-%%-GO:0060079-&&-excitatory postsynaptic potential-%%-GO:0006811-&&-ion transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0097061-&&-dendritic spine organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005892-&&-acetylcholine-gated channel complex-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030054-&&-cell junction|molecular_function-&-1&-GO:0017081-&&-chloride channel regulator activity-%%-GO:0015276-&&-ligand-gated ion channel activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0015464-&&-acetylcholine receptor activity-%%-GO:0015643-&&-toxic substance binding-%%-GO:0022848-&&-acetylcholine-gated cation-selective channel activity-%%-GO:0005216-&&-ion channel activity-%%-GO:0005262-&&-calcium channel activity-%%-GO:0042166-&&-acetylcholine binding-%%-GO:0001540-&&-beta-amyloid binding	G:9606:CHRNA7	CHRNA7	TRUE	KEGG-&-1&-hsa04725-&&-Cholinergic synapse-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa05033-&&-Nicotine addiction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05204-&&-Chemical carcinogenesis	CHRNA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CHRNA7	0.35761776	0.3	5	5	FALSE	CHRNA7	CHRNA7	331.8	0	5	0	0.70061972	FALSE	0	CHRNA7	6190	0.22696783
792368	taxon:9606	2.71466835	2.29E-06	165757	1902	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGAP3			KEGG-&-1&-hsa04144-&&-Endocytosis	AGAP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGAP3	0.36836912	0.3	5	4	FALSE	AGAP3	AGAP3	468.2	0	5	0	0.71422194	FALSE	0	AGAP3	4090	0.2354303
792375	taxon:9606	3.18969592	1.85E-06	182128	1902	claudin 4	gene	biological_process-&-1&-GO:0007623-&&-circadian rhythm-%%-GO:0016338-&&-calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules-%%-GO:0007565-&&-female pregnancy-%%-GO:0007165-&&-signal transduction-%%-GO:0032570-&&-response to progesterone-%%-GO:0061436-&&-establishment of skin barrier|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0009925-&&-basal plasma membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0016327-&&-apicolateral plasma membrane|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0042802-&&-identical protein binding-%%-GO:0004888-&&-transmembrane signaling receptor activity	G:9606:CLDN4	CLDN4	TRUE	KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04670-&&-Leukocyte transendothelial migration-%%-hsa05160-&&-Hepatitis C-%%-hsa04530-&&-Tight junction	CLDN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CLDN4	0.31350951	0.1	5	5	FALSE	CLDN4	CLDN4	36.8	0	5	0	0.63505068	FALSE	0	CLDN4	1718	0.21294118
792495	taxon:9606	2.90909091	5.00E-08	181908	1902	pituitary tumor-transforming 1 interacting protein	gene	biological_process-&-1&-GO:0043518-&&-negative regulation of DNA damage response, signal transduction by p53 class mediator-%%-GO:1902254-&&-negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0031398-&&-positive regulation of protein ubiquitination-%%-GO:1903364-&&-positive regulation of cellular protein catabolic process-%%-GO:0006606-&&-protein import into nucleus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0002039-&&-p53 binding-%%-GO:0005515-&&-protein binding	G:9606:PTTG1IP				PTTG1IP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTTG1IP	0.34375	0.66666667	5	5	FALSE	PTTG1IP	PTTG1IP	335.6666667	0	4	0	0.68181818	FALSE	1	PTTG1IP	60	0.34043272
792642	taxon:9606	3.07168741	4.60E-07	181653	1902	CD37 molecule	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0001772-&&-immunological synapse-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CD37			KEGG-&-1&-hsa04640-&&-Hematopoietic cell lineage	CD37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD37	0.32555396	0.6	5	5	FALSE	CD37	CD37	81.2	0	5	0	0.65471876	FALSE	0	CD37	544	0.26363636
792656	taxon:9606	3.49787301	9.00E-08	181624	1902	cytochrome P450 family 2 subfamily D member 6	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0033076-&&-isoquinoline alkaloid metabolic process-%%-GO:0090350-&&-negative regulation of cellular organofluorine metabolic process-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0009804-&&-coumarin metabolic process-%%-GO:0009820-&&-alkaloid metabolic process-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0051100-&&-negative regulation of binding-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0042737-&&-drug catabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0009822-&&-alkaloid catabolic process-%%-GO:0070989-&&-oxidative demethylation|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0008144-&&-drug binding-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0070330-&&-aromatase activity-%%-GO:0016712-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-%%-GO:0020037-&&-heme binding	G:9606:CYP2D6			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa01522-&&-Endocrine resistance-%%-hsa04726-&&-Serotonergic synapse-%%-hsa00982-&&-Drug metabolism - cytochrome P450	CYP2D6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP2D6	0.28588802	0.66666667	5	5	FALSE	CYP2D6	CYP2D6	20.33333333	0	4	0	0.58368783	FALSE	1	CYP2D6	40	0.39869281
792662	taxon:9606	3.04584843	1.30E-07	181601	1902	cytochrome P450 family 27 subfamily A member 1	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0016125-&&-sterol metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0008395-&&-steroid hydroxylase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0016705-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen-%%-GO:0020037-&&-heme binding	G:9606:CYP27A1			KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa00120-&&-Primary bile acid biosynthesis	CYP27A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP27A1	0.32831575	0.4	5	5	FALSE	CYP27A1	CYP27A1	91.2	0	5	0	0.65902526	FALSE	0	CYP27A1	282	0.24728261
792703	taxon:9606	3.06664566	4.16E-06	181539	1902	defensin alpha 1	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0019731-&&-antibacterial humoral response-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0045087-&&-innate immune response-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0002227-&&-innate immune response in mucosa-%%-GO:0050832-&&-defense response to fungus-%%-GO:0006955-&&-immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0031640-&&-killing of cells of other organism-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0005796-&&-Golgi lumen-%%-GO:0005576-&&-extracellular region	G:9606:DEFA1			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05150-&&-Staphylococcus aureus infection	DEFA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DEFA1	0.32608919	0	5	5	FALSE	DEFA1	DEFA1	82	0	5	0	0.65555906	FALSE	0	DEFA1	2836	0.20716113
792729	taxon:9606	2.95840555	2.10E-07	165103	1902	zinc finger protein 787	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF787				ZNF787	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF787	0.33801992	0.5	5	5	FALSE	ZNF787	ZNF787	296	0	5	0	0.67359908	FALSE	0	ZNF787	970	0.32434211
792751	taxon:9606	3.12178982	2.90E-06	181437	1902	ferredoxin reductase	gene	biological_process-&-1&-GO:0008203-&&-cholesterol metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0016125-&&-sterol metabolic process-%%-GO:0006700-&&-C21-steroid hormone biosynthetic process-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0006694-&&-steroid biosynthetic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0015039-&&-NADPH-adrenodoxin reductase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004324-&&-ferredoxin-NADP+ reductase activity	G:9606:FDXR				FDXR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FDXR	0.32032906	0	5	5	FALSE	FDXR	FDXR	58.2	0	5	0	0.64636836	FALSE	0	FDXR	1948	0.20212014
792897	taxon:9606	2.71876477	8.70E-07	164817	1902	mitochondrial transcription termination factor 4	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0032502-&&-developmental process-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006390-&&-transcription from mitochondrial promoter-%%-GO:0031167-&&-rRNA methylation-%%-GO:0042255-&&-ribosome assembly-%%-GO:0043010-&&-camera-type eye development-%%-GO:0008380-&&-RNA splicing-%%-GO:0006626-&&-protein targeting to mitochondrion|cellular_component-&-1&-GO:0005762-&&-mitochondrial large ribosomal subunit-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0019843-&&-rRNA binding	G:9606:MTERF4				MTERF4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTERF4	0.36781409	0.2	5	4	FALSE	MTERF4	MTERF4	440.8	0	5	0	0.7135392	FALSE	0	MTERF4	3924	0.23264659
792901	taxon:9606	2.89522609	9.90E-07	181197	1902	fatty acid binding protein 1	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0044255-&&-cellular lipid metabolic process-%%-GO:0050892-&&-intestinal absorption-%%-GO:0019433-&&-triglyceride catabolic process-%%-GO:0051345-&&-positive regulation of hydrolase activity-%%-GO:0043154-&&-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0015909-&&-long-chain fatty acid transport-%%-GO:0032000-&&-positive regulation of fatty acid beta-oxidation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005829-&&-cytosol-%%-GO:0005782-&&-peroxisomal matrix-%%-GO:0045179-&&-apical cortex|molecular_function-&-1&-GO:0005543-&&-phospholipid binding-%%-GO:0008144-&&-drug binding-%%-GO:0032052-&&-bile acid binding-%%-GO:0005504-&&-fatty acid binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0016209-&&-antioxidant activity-%%-GO:0005324-&&-long-chain fatty acid transporter activity	G:9606:FABP1			KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa03320-&&-PPAR signaling pathway	FABP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FABP1	0.34539617	0.3	5	5	FALSE	FABP1	FABP1	211.6	0	5	0	0.68412898	FALSE	0	FABP1	1590	0.22804746
792924	taxon:9606	3.09059398	3.30E-06	181139	1902	glutamate decarboxylase 2	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0006540-&&-glutamate decarboxylation to succinate-%%-GO:0042493-&&-response to drug-%%-GO:0042136-&&-neurotransmitter biosynthetic process-%%-GO:0007269-&&-neurotransmitter secretion|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0060077-&&-inhibitory synapse-%%-GO:0061202-&&-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0030424-&&-axon-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0030672-&&-synaptic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0031225-&&-anchored component of membrane|molecular_function-&-1&-GO:0016595-&&-glutamate binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005515-&&-protein binding-%%-GO:0004351-&&-glutamate decarboxylase activity-%%-GO:0030170-&&-pyridoxal phosphate binding	G:9606:GAD2	GAD2	TRUE	KEGG-&-1&-hsa00250-&&-Alanine, aspartate and glutamate metabolism-%%-hsa00430-&&-Taurine and hypotaurine metabolism-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa00410-&&-beta-Alanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04727-&&-GABAergic synapse-%%-hsa00650-&&-Butanoate metabolism	GAD2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GAD2	0.3235624	0.3	5	5	FALSE	GAD2	GAD2	63.4	0	5	0	0.65156767	FALSE	0	GAD2	2752	0.21279461
792993	taxon:9606	2.9021585	8.16E-06	181028	1902	fibromodulin	gene	biological_process-&-1&-GO:0007181-&&-transforming growth factor beta receptor complex assembly-%%-GO:0018146-&&-keratan sulfate biosynthetic process-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0007409-&&-axonogenesis-%%-GO:0042340-&&-keratan sulfate catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0043202-&&-lysosomal lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005796-&&-Golgi lumen	G:9606:FMOD			KEGG-&-1&-hsa04350-&&-TGF-beta signaling pathway	FMOD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FMOD	0.34457112	0.2	5	5	FALSE	FMOD	FMOD	208.6	0	5	0	0.68297358	FALSE	0	FMOD	7670	0.20613254
793013	taxon:9606	2.87175043	4.88E-06	180893	1902	G protein-coupled receptor kinase 4	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0031623-&&-receptor internalization-%%-GO:0002031-&&-G-protein coupled receptor internalization-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005938-&&-cell cortex-%%-GO:0030425-&&-dendrite-%%-GO:0097381-&&-photoreceptor disc membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0050254-&&-rhodopsin kinase activity	G:9606:GRK4			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa05032-&&-Morphine addiction-%%-hsa04062-&&-Chemokine signaling pathway	GRK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK4	0.34821967	0.1	5	5	FALSE	GRK4	GRK4	240.6	0	5	0	0.68804159	FALSE	0	GRK4	4364	0.23166023
793018	taxon:9606	2.82432645	3.00E-07	180884	1902	glutathione peroxidase 2	gene	biological_process-&-1&-GO:0055114-&&-oxidation-reduction process-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:0000302-&&-response to reactive oxygen species|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0009055-&&-electron carrier activity	G:9606:GPX2			KEGG-&-1&-hsa00480-&&-Glutathione metabolism-%%-hsa04918-&&-Thyroid hormone synthesis-%%-hsa00590-&&-Arachidonic acid metabolism	GPX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPX2	0.35406672	0.33333333	5	4	FALSE	GPX2	GPX2	537	0	4	0	0.69594559	FALSE	1	GPX2	964	0.38305972
793056	taxon:9606	3.62123838	1.80E-07	180823	1902	glutathione S-transferase mu 2	gene	biological_process-&-1&-GO:0006749-&&-glutathione metabolic process-%%-GO:0060316-&&-positive regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0018916-&&-nitrobenzene metabolic process-%%-GO:0071313-&&-cellular response to caffeine-%%-GO:0098869-&&-cellular oxidant detoxification-%%-GO:1901687-&&-glutathione derivative biosynthetic process-%%-GO:0010881-&&-regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion-%%-GO:0014809-&&-regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion-%%-GO:0043651-&&-linoleic acid metabolic process-%%-GO:0055119-&&-relaxation of cardiac muscle-%%-GO:0010880-&&-regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum-%%-GO:0060315-&&-negative regulation of ryanodine-sensitive calcium-release channel activity-%%-GO:0042178-&&-xenobiotic catabolic process-%%-GO:0070458-&&-cellular detoxification of nitrogen compound|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004602-&&-glutathione peroxidase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043295-&&-glutathione binding-%%-GO:0004364-&&-glutathione transferase activity-%%-GO:0005102-&&-receptor binding	G:9606:GSTM2	GSTM2	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTM2	0.27614863	0.66666667	5	5	FALSE	GSTM2	GSTM2	12.33333333	0	4	0	0.56312694	FALSE	1	GSTM2	298	0.38541667
793131	taxon:9606	3.18922326	3.72E-06	164289	1902	solute carrier family 38 member 6	gene	biological_process-&-1&-GO:0003333-&&-amino acid transmembrane transport-%%-GO:0006814-&&-sodium ion transport|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0015171-&&-amino acid transmembrane transporter activity	G:9606:SLC38A6				SLC38A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC38A6	0.31355597	0	5	5	FALSE	SLC38A6	SLC38A6	44.4	0	5	0	0.63512946	FALSE	0	SLC38A6	2042	0.2137931
793132	taxon:9606	2.88498503	1.13E-06	180675	1902	gap junction protein alpha 3	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0006810-&&-transport-%%-GO:0007601-&&-visual perception-%%-GO:0055085-&&-transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005922-&&-connexin complex|molecular_function-&-1&-GO:0005243-&&-gap junction channel activity	G:9606:GJA3				GJA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJA3	0.34662225	0.3	5	4	FALSE	GJA3	GJA3	219.8	0	5	0	0.68583583	FALSE	0	GJA3	3332	0.2127907
793134	taxon:9606	2.95462423	2.44E-06	180668	1902	gap junction protein beta 5	gene	biological_process-&-1&-GO:0060713-&&-labyrinthine layer morphogenesis-%%-GO:0007154-&&-cell communication-%%-GO:0008544-&&-epidermis development-%%-GO:0060708-&&-spongiotrophoblast differentiation-%%-GO:0060707-&&-trophoblast giant cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005922-&&-connexin complex	G:9606:GJB5				GJB5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJB5	0.33845251	0	5	5	FALSE	GJB5	GJB5	141.8	0	5	0	0.67422929	FALSE	0	GJB5	2270	0.21204819
793152	taxon:9606	2.85615251	1.06E-06	164248	1902	tau tubulin kinase 2	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0097711-&&-ciliary basal body docking|cellular_component-&-1&-GO:0035869-&&-ciliary transition zone-%%-GO:0005814-&&-centriole-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:TTBK2				TTBK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTBK2	0.35012136	0.1	5	4	FALSE	TTBK2	TTBK2	299.8	0	5	0	0.69064125	FALSE	0	TTBK2	2834	0.24891847
793240	taxon:9606	2.87332598	3.30E-07	164088	1902	unc-45 myosin chaperone B	gene	biological_process-&-1&-GO:0007517-&&-muscle organ development-%%-GO:0002088-&&-lens development in camera-type eye-%%-GO:0030154-&&-cell differentiation-%%-GO:0061077-&&-chaperone-mediated protein folding|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0051879-&&-Hsp90 protein binding-%%-GO:0005515-&&-protein binding	G:9606:UNC45B				UNC45B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UNC45B	0.34802873	0.2	5	5	FALSE	UNC45B	UNC45B	242.2	0	5	0	0.687779	FALSE	0	UNC45B	894	0.2325
793263	taxon:9606	2.83645817	6.46E-06	180408	1902	guanylate cyclase 1 soluble subunit beta	gene	biological_process-&-1&-GO:0007263-&&-nitric oxide mediated signal transduction-%%-GO:0071732-&&-cellular response to nitric oxide-%%-GO:0006182-&&-cGMP biosynthetic process-%%-GO:0038060-&&-nitric oxide-cGMP-mediated signaling pathway-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0008074-&&-guanylate cyclase complex, soluble-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0020037-&&-heme binding-%%-GO:0004016-&&-adenylate cyclase activity-%%-GO:0004383-&&-guanylate cyclase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:GUCY1B3			KEGG-&-1&-hsa04924-&&-Renin secretion-%%-hsa04540-&&-Gap junction-%%-hsa04730-&&-Long-term depression-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04713-&&-Circadian entrainment-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa00230-&&-Purine metabolism-%%-hsa04970-&&-Salivary secretion-%%-hsa04022-&&-cGMP-PKG signaling pathway	GUCY1B3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUCY1B3	0.35255235	0.4	5	4	FALSE	GUCY1B3	GUCY1B3	262.8	0	5	0	0.69392364	FALSE	0	GUCY1B3	4664	0.21210654
793265	taxon:9606	3.04931464	1.47E-06	164021	1902	NLR family pyrin domain containing 4	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0032479-&&-regulation of type I interferon production|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:NLRP4				NLRP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP4	0.32794254	0.1	5	5	FALSE	NLRP4	NLRP4	72	0	5	0	0.65844756	FALSE	0	NLRP4	1502	0.23106796
793291	taxon:9606	2.81991492	8.00E-08	180364	1902	hyaluronan synthase 1	gene	biological_process-&-1&-GO:0085029-&&-extracellular matrix assembly-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0030213-&&-hyaluronan biosynthetic process-%%-GO:0044849-&&-estrous cycle-%%-GO:0007155-&&-cell adhesion-%%-GO:0045226-&&-extracellular polysaccharide biosynthetic process-%%-GO:0010764-&&-negative regulation of fibroblast migration-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0050501-&&-hyaluronan synthase activity	G:9606:HAS1	HAS1	TRUE		HAS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAS1	0.35462063	0.2	5	5	FALSE	HAS1	HAS1	369.2	0	5	0	0.69668085	FALSE	0	HAS1	606	0.26880466
787062	taxon:9606	3.20261541	1.08E-06	180139	1902	interferon alpha 14	gene	biological_process-&-1&-GO:0002250-&&-adaptive immune response-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0045087-&&-innate immune response-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0043330-&&-response to exogenous dsRNA-%%-GO:0002323-&&-natural killer cell activation involved in immune response-%%-GO:0030183-&&-B cell differentiation-%%-GO:0006959-&&-humoral immune response-%%-GO:0051607-&&-defense response to virus-%%-GO:0002286-&&-T cell activation involved in immune response-%%-GO:0007596-&&-blood coagulation-%%-GO:0033141-&&-positive regulation of peptidyl-serine phosphorylation of STAT protein-%%-GO:0042100-&&-B cell proliferation-%%-GO:0060338-&&-regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005125-&&-cytokine activity-%%-GO:0005132-&&-type I interferon receptor binding-%%-GO:0005126-&&-cytokine receptor binding	G:9606:IFNA14			KEGG-&-1&-hsa05162-&&-Measles-%%-hsa04650-&&-Natural killer cell mediated cytotoxicity-%%-hsa05170-&&-Human immunodeficiency virus 1 infection-%%-hsa05168-&&-Herpes simplex infection-%%-hsa05160-&&-Hepatitis C-%%-hsa05152-&&-Tuberculosis-%%-hsa05161-&&-Hepatitis B-%%-hsa05164-&&-Influenza A-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05169-&&-Epstein-Barr virus infection-%%-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04622-&&-RIG-I-like receptor signaling pathway-%%-hsa04217-&&-Necroptosis	IFNA14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFNA14	0.3122448	0.16666667	4	5	FALSE	IFNA14	IFNA14	59.75	0	4	0	0.63289743	FALSE	0	IFNA14	822	0.25538793
787077	taxon:9606	3.52639042	4.67E-06	180115	1902	insulin like growth factor binding protein 1	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007568-&&-aging-%%-GO:0036499-&&-PERK-mediated unfolded protein response-%%-GO:0008286-&&-insulin receptor signaling pathway-%%-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0042246-&&-tissue regeneration-%%-GO:0007165-&&-signal transduction-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0005520-&&-insulin-like growth factor binding	G:9606:IGFBP1	IGFBP1	TRUE		IGFBP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP1	0.28357609	0.33333333	4	5	FALSE	IGFBP1	IGFBP1	18.5	0	4	0	0.57893493	FALSE	0	IGFBP1	4620	0.33796296
787078	taxon:9606	3.40412793	7.40E-07	180114	1902	insulin like growth factor binding protein 2	gene	biological_process-&-1&-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0010226-&&-response to lithium ion-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0043627-&&-response to estrogen-%%-GO:0042493-&&-response to drug-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0044267-&&-cellular protein metabolic process-%%-GO:0007568-&&-aging-%%-GO:0032355-&&-response to estradiol-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0007565-&&-female pregnancy-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0007584-&&-response to nutrient-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0031995-&&-insulin-like growth factor II binding-%%-GO:0005515-&&-protein binding-%%-GO:0031994-&&-insulin-like growth factor I binding	G:9606:IGFBP2	IGFBP2	TRUE		IGFBP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP2	0.29376099	0.33333333	4	5	FALSE	IGFBP2	IGFBP2	22.5	0	4	0	0.59931201	FALSE	0	IGFBP2	340	0.31785714
787082	taxon:9606	3.29242162	1.99E-06	180110	1902	insulin like growth factor binding protein 6	gene	biological_process-&-1&-GO:0044267-&&-cellular protein metabolic process-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007165-&&-signal transduction-%%-GO:0043567-&&-regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0031994-&&-insulin-like growth factor I binding-%%-GO:0031995-&&-insulin-like growth factor II binding	G:9606:IGFBP6	IGFBP6	TRUE		IGFBP6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IGFBP6	0.30372781	0.33333333	4	5	FALSE	IGFBP6	IGFBP6	45.25	0	4	0	0.61792973	FALSE	0	IGFBP6	1564	0.28481013
787118	taxon:9606	3.04947219	1.85E-04	180034	1902	interleukin 10 receptor subunit alpha	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0050807-&&-regulation of synapse organization|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0019969-&&-interleukin-10 binding-%%-GO:0004871-&&-signal transducer activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0004920-&&-interleukin-10 receptor activity	G:9606:IL10RA			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	IL10RA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL10RA	0.3279256	0.16666667	4	5	FALSE	IL10RA	IL10RA	88	0	4	0	0.6584213	FALSE	0	IL10RA	111202	0.25584795
787129	taxon:9606	3.11611785	3.20E-07	180018	1902	interleukin 18	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032819-&&-positive regulation of natural killer cell proliferation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0042231-&&-interleukin-13 biosynthetic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0042095-&&-interferon-gamma biosynthetic process-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0001525-&&-angiogenesis-%%-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0035655-&&-interleukin-18-mediated signaling pathway-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0042088-&&-T-helper 1 type immune response-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0051142-&&-positive regulation of NK T cell proliferation-%%-GO:0042033-&&-chemokine biosynthetic process-%%-GO:0042253-&&-granulocyte macrophage colony-stimulating factor biosynthetic process-%%-GO:0034105-&&-positive regulation of tissue remodeling-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0031663-&&-lipopolysaccharide-mediated signaling pathway-%%-GO:0042094-&&-interleukin-2 biosynthetic process-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0006955-&&-immune response-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:0006954-&&-inflammatory response-%%-GO:0032148-&&-activation of protein kinase B activity-%%-GO:0042092-&&-type 2 immune response-%%-GO:0030155-&&-regulation of cell adhesion-%%-GO:0032725-&&-positive regulation of granulocyte macrophage colony-stimulating factor production-%%-GO:0014068-&&-positive regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0030431-&&-sleep-%%-GO:0032729-&&-positive regulation of interferon-gamma production|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity	G:9606:IL18	IL18	TRUE	KEGG-&-1&-hsa05143-&&-African trypanosomiasis-%%-hsa05132-&&-Salmonella infection-%%-hsa04623-&&-Cytosolic DNA-sensing pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04621-&&-NOD-like receptor signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05164-&&-Influenza A-%%-hsa05134-&&-Legionellosis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05144-&&-Malaria-%%-hsa05323-&&-Rheumatoid arthritis	IL18	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL18	0.32091212	0.16666667	4	5	FALSE	IL18	IL18	76.75	0	4	0	0.64731369	FALSE	0	IL18	384	0.28992395
787290	taxon:9606	2.83346463	6.50E-07	179728	1902	potassium calcium-activated channel subfamily N member 3	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005516-&&-calmodulin binding-%%-GO:0016286-&&-small conductance calcium-activated potassium channel activity	G:9606:KCNN3	KCNN3	TRUE	KEGG-&-1&-hsa04911-&&-Insulin secretion	KCNN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNN3	0.35292482	0.33333333	4	5	FALSE	KCNN3	KCNN3	344.75	0	4	0	0.69442256	FALSE	0	KCNN3	1424	0.26893052
787300	taxon:9606	2.88955412	1.11E-05	179700	1902	KiSS-1 metastasis-suppressor	gene	biological_process-&-1&-GO:0051482-&&-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0046697-&&-decidualization-%%-GO:0043410-&&-positive regulation of MAPK cascade-%%-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0033686-&&-positive regulation of luteinizing hormone secretion-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:0060112-&&-generation of ovulation cycle rhythm|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0043005-&&-neuron projection-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0031773-&&-kisspeptin receptor binding-%%-GO:0005515-&&-protein binding	G:9606:KISS1	KISS1	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	KISS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KISS1	0.34607415	0.16666667	4	4	FALSE	KISS1	KISS1	277.25	0	4	0	0.68507431	FALSE	0	KISS1	15754	0.26010338
787362	taxon:9606	3.12951	1.96E-06	163187	1902	secretory carrier membrane protein 5	gene	biological_process-&-1&-GO:0045806-&&-negative regulation of endocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0006887-&&-exocytosis-%%-GO:0045956-&&-positive regulation of calcium ion-dependent exocytosis-%%-GO:0034976-&&-response to endoplasmic reticulum stress-%%-GO:0050715-&&-positive regulation of cytokine secretion|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0031201-&&-SNARE complex-%%-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030054-&&-cell junction-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0055038-&&-recycling endosome membrane-%%-GO:0030672-&&-synaptic vesicle membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SCAMP5				SCAMP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAMP5	0.31953884	0	4	5	FALSE	SCAMP5	SCAMP5	91.5	0	4	0	0.64508167	FALSE	0	SCAMP5	1774	0.25492958
787384	taxon:9606	2.91870175	8.00E-08	179523	1902	myosin light chain 4	gene	biological_process-&-1&-GO:0030049-&&-muscle filament sliding-%%-GO:0032781-&&-positive regulation of ATPase activity-%%-GO:0060048-&&-cardiac muscle contraction-%%-GO:0002026-&&-regulation of the force of heart contraction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016459-&&-myosin complex-%%-GO:0031672-&&-A band|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0032038-&&-myosin II heavy chain binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0005509-&&-calcium ion binding	G:9606:MYL4			KEGG-&-1&-hsa04260-&&-Cardiac muscle contraction-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes	MYL4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYL4	0.34261808	0.5	4	5	FALSE	MYL4	MYL4	438.75	0	4	0	0.68021638	FALSE	0	MYL4	476	0.46184211
787465	taxon:9606	2.78021112	7.10E-07	179389	1902	microfibrillar associated protein 4	gene	biological_process-&-1&-GO:0009650-&&-UV protection-%%-GO:0097435-&&-supramolecular fiber organization-%%-GO:0007155-&&-cell adhesion-%%-GO:0071493-&&-cellular response to UV-B-%%-GO:0010712-&&-regulation of collagen metabolic process-%%-GO:0048251-&&-elastic fiber assembly|cellular_component-&-1&-GO:0001527-&&-microfibril-%%-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix-%%-GO:0071953-&&-elastic fiber|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:MFAP4				MFAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MFAP4	0.35968491	0.16666667	4	4	FALSE	MFAP4	MFAP4	443.75	0	4	0	0.70329815	FALSE	0	MFAP4	2102	0.28819896
787557	taxon:9606	2.76760674	1.40E-07	179181	1902	mature T-cell proliferation 1	gene	biological_process-&-1&-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0005739-&&-mitochondrion	G:9606:MTCP1			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway	MTCP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTCP1	0.36132301	0.5	4	4	FALSE	MTCP1	MTCP1	455.25	0	4	0	0.70539888	FALSE	0	MTCP1	748	0.284375
787669	taxon:9606	3.23822278	7.20E-07	178984	1902	serpin family I member 1	gene	biological_process-&-1&-GO:0007422-&&-peripheral nervous system development-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0007417-&&-central nervous system development-%%-GO:0030155-&&-regulation of cell adhesion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINI1				SERPINI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINI1	0.30881137	0.16666667	4	5	FALSE	SERPINI1	SERPINI1	37.75	0	4	0	0.62696287	FALSE	0	SERPINI1	484	0.27798507
787737	taxon:9606	2.869072	9.10E-07	162474	1902	docking protein 6	gene	biological_process-&-1&-GO:0007411-&&-axon guidance|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005158-&&-insulin receptor binding	G:9606:DOK6				DOK6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOK6	0.34854476	0.33333333	4	5	FALSE	DOK6	DOK6	321.25	0	4	0	0.688488	FALSE	0	DOK6	1672	0.2899729
787754	taxon:9606	3.10319836	2.91E-06	178838	1902	POU class 3 homeobox 3	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0021799-&&-cerebral cortex radially oriented cell migration-%%-GO:0021869-&&-forebrain ventricular zone progenitor cell division-%%-GO:0072233-&&-metanephric thick ascending limb development-%%-GO:0007588-&&-excretion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048878-&&-chemical homeostasis-%%-GO:0072236-&&-metanephric loop of Henle development-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0072227-&&-metanephric macula densa development-%%-GO:0072240-&&-metanephric DCT cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072218-&&-metanephric ascending thin limb development-%%-GO:0007417-&&-central nervous system development-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0071837-&&-HMG box domain binding	G:9606:POU3F3	POU3F3	TRUE		POU3F3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU3F3	0.32224817	0	4	5	FALSE	POU3F3	POU3F3	64.5	0	4	0	0.64946694	FALSE	0	POU3F3	1628	0.2602459
787859	taxon:9606	2.89018434	1.16E-05	178697	1902	protease, serine 2	gene	biological_process-&-1&-GO:0030574-&&-collagen catabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0019730-&&-antimicrobial humoral response-%%-GO:0007586-&&-digestion-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0006508-&&-proteolysis-%%-GO:0045785-&&-positive regulation of cell adhesion|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0008236-&&-serine-type peptidase activity	G:9606:PRSS2			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05164-&&-Influenza A-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04974-&&-Protein digestion and absorption	PRSS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRSS2	0.34599869	0	4	4	FALSE	PRSS2	PRSS2	271.75	0	4	0	0.68496928	FALSE	0	PRSS2	13270	0.25639205
787868	taxon:9606	2.94485584	4.32E-06	178672	1902	protein serine kinase H1	gene	biological_process-&-1&-GO:0007507-&&-heart development-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0007368-&&-determination of left/right symmetry-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PSKH1				PSKH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PSKH1	0.3395752	0	4	5	FALSE	PSKH1	PSKH1	184.5	0	4	0	0.67585736	FALSE	0	PSKH1	3440	0.25521558
787883	taxon:9606	3.17378289	5.80E-07	162273	1902	glutamyl-tRNA amidotransferase subunit C	gene	biological_process-&-1&-GO:0032543-&&-mitochondrial translation-%%-GO:0070681-&&-glutaminyl-tRNAGln biosynthesis via transamidation-%%-GO:0006450-&&-regulation of translational fidelity|cellular_component-&-1&-GO:0030956-&&-glutamyl-tRNA(Gln) amidotransferase complex-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0050567-&&-glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity-%%-GO:0005515-&&-protein binding	G:9606:GATC			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis-%%-hsa01100-&&-Metabolic pathways	GATC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GATC	0.31508141	0	4	5	FALSE	GATC	GATC	53.25	0	4	0	0.63770285	FALSE	0	GATC	476	0.25866337
787913	taxon:9606	2.82275091	3.11E-06	178626	1902	prostaglandin D2 receptor	gene	biological_process-&-1&-GO:0071799-&&-cellular response to prostaglandin D stimulus-%%-GO:0046085-&&-adenosine metabolic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0071380-&&-cellular response to prostaglandin E stimulus-%%-GO:0006954-&&-inflammatory response-%%-GO:0030431-&&-sleep-%%-GO:0030238-&&-male sex determination|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004957-&&-prostaglandin E receptor activity-%%-GO:0004956-&&-prostaglandin D receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0001785-&&-prostaglandin J receptor activity	G:9606:PTGDR			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	PTGDR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGDR	0.35426434	0.16666667	4	5	FALSE	PTGDR	PTGDR	402.75	0	4	0	0.69620818	FALSE	0	PTGDR	4520	0.29996271
787918	taxon:9606	2.85473452	5.26E-06	178615	1902	prostaglandin I2 synthase	gene	biological_process-&-1&-GO:0071354-&&-cellular response to interleukin-6-%%-GO:0019371-&&-cyclooxygenase pathway-%%-GO:1900119-&&-positive regulation of execution phase of apoptosis-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0001516-&&-prostaglandin biosynthetic process-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0045019-&&-negative regulation of nitric oxide biosynthetic process-%%-GO:0035360-&&-positive regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0046697-&&-decidualization-%%-GO:0006690-&&-icosanoid metabolic process-%%-GO:0007566-&&-embryo implantation-%%-GO:0034356-&&-NAD biosynthesis via nicotinamide riboside salvage pathway-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0097190-&&-apoptotic signaling pathway|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005901-&&-caveola|molecular_function-&-1&-GO:0004497-&&-monooxygenase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0016705-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen-%%-GO:0005515-&&-protein binding-%%-GO:0008116-&&-prostaglandin-I synthase activity-%%-GO:0020037-&&-heme binding	G:9606:PTGIS			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00590-&&-Arachidonic acid metabolism	PTGIS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGIS	0.35029527	0.83333333	4	5	FALSE	PTGIS	PTGIS	307.5	0	4	0	0.69087758	FALSE	0	PTGIS	2712	0.26214834
788024	taxon:9606	2.99401292	7.40E-07	178368	1902	ring finger protein 6	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0060765-&&-regulation of androgen receptor signaling pathway-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process-%%-GO:0030517-&&-negative regulation of axon extension-%%-GO:0085020-&&-protein K6-linked ubiquitination-%%-GO:0070936-&&-protein K48-linked ubiquitination-%%-GO:0044314-&&-protein K27-linked ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0030424-&&-axon-%%-GO:0031965-&&-nuclear membrane-%%-GO:0016605-&&-PML body-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0050681-&&-androgen receptor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RNF6				RNF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF6	0.33399989	0	4	5	FALSE	RNF6	RNF6	154.25	0	4	0	0.66766451	FALSE	0	RNF6	1198	0.27415027
788158	taxon:9606	3.15172522	4.40E-07	178150	1902	RAB27B, member RAS oncogene family	gene	biological_process-&-1&-GO:0032402-&&-melanosome transport-%%-GO:0045921-&&-positive regulation of exocytosis-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0002576-&&-platelet degranulation-%%-GO:0071985-&&-multivesicular body sorting pathway|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005795-&&-Golgi stack-%%-GO:0030140-&&-trans-Golgi network transport vesicle-%%-GO:0042470-&&-melanosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031088-&&-platelet dense granule membrane-%%-GO:0042589-&&-zymogen granule membrane-%%-GO:0030141-&&-secretory granule-%%-GO:0032585-&&-multivesicular body membrane|molecular_function-&-1&-GO:0003924-&&-GTPase activity-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0031489-&&-myosin V binding-%%-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0019003-&&-GDP binding	G:9606:RAB27B			KEGG-&-1&-hsa04972-&&-Pancreatic secretion	RAB27B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB27B	0.31728654	0	4	5	FALSE	RAB27B	RAB27B	115	0	3	0	0.64137913	FALSE	1	RAB27B	412	0.50442478
788327	taxon:9606	2.96155664	1.30E-07	161494	1902	kelch like family member 10	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0007286-&&-spermatid development-%%-GO:0000902-&&-cell morphogenesis-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0008584-&&-male gonad development-%%-GO:0048808-&&-male genitalia morphogenesis-%%-GO:0048873-&&-homeostasis of number of cells within a tissue|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL10				KLHL10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL10	0.33766026	0	4	5	FALSE	KLHL10	KLHL10	358.5	0	3	0	0.67307389	FALSE	1	KLHL10	428	0.53199405
788349	taxon:9606	3.10634946	1.79E-05	177829	1902	C-C motif chemokine ligand 17	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0045662-&&-negative regulation of myoblast differentiation-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0007275-&&-multicellular organism development-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0008009-&&-chemokine activity-%%-GO:0031729-&&-CCR4 chemokine receptor binding-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL17			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL17	0.32192128	0	4	5	FALSE	CCL17	CCL17	228.5	0	3	0	0.64894176	FALSE	1	CCL17	24086	0.5
788352	taxon:9606	3.01370726	5.85E-06	177823	1902	C-C motif chemokine ligand 22	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0009615-&&-response to virus-%%-GO:0030593-&&-neutrophil chemotaxis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0002548-&&-monocyte chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0048247-&&-lymphocyte chemotaxis-%%-GO:0071346-&&-cellular response to interferon-gamma-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0006954-&&-inflammatory response-%%-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0048020-&&-CCR chemokine receptor binding	G:9606:CCL22			KEGG-&-1&-hsa04062-&&-Chemokine signaling pathway-%%-hsa04625-&&-C-type lectin receptor signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	CCL22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCL22	0.33181723	0	4	5	FALSE	CCL22	CCL22	144.75	0	4	0	0.66438212	FALSE	0	CCL22	5692	0.25442478
788421	taxon:9606	2.79533638	1.58E-06	177703	1902	selenoprotein P	gene	biological_process-&-1&-GO:0019953-&&-sexual reproduction-%%-GO:0040007-&&-growth-%%-GO:0001887-&&-selenium compound metabolic process-%%-GO:0009791-&&-post-embryonic development-%%-GO:0007626-&&-locomotory behavior-%%-GO:0007420-&&-brain development-%%-GO:0006979-&&-response to oxidative stress-%%-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031089-&&-platelet dense granule lumen|molecular_function-&-1&-GO:0008430-&&-selenium binding	G:9606:SELENOP				SELENOP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SELENOP	0.3577387	0.16666667	4	5	FALSE	SELENOP	SELENOP	388.5	0	4	0	0.70077727	FALSE	0	SELENOP	4140	0.27189909
788453	taxon:9606	2.85694029	8.30E-07	177647	1902	solute carrier family 5 member 1	gene	biological_process-&-1&-GO:0015758-&&-glucose transport-%%-GO:0001951-&&-intestinal D-glucose absorption-%%-GO:0006814-&&-sodium ion transport-%%-GO:1904659-&&-glucose transmembrane transport-%%-GO:0008645-&&-hexose transport|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0031526-&&-brush border membrane|molecular_function-&-1&-GO:0005412-&&-glucose:sodium symporter activity-%%-GO:0005515-&&-protein binding	G:9606:SLC5A1			KEGG-&-1&-hsa04978-&&-Mineral absorption-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa04976-&&-Bile secretion	SLC5A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC5A1	0.35002482	0.33333333	4	5	FALSE	SLC5A1	SLC5A1	352	0	4	0	0.69050995	FALSE	0	SLC5A1	1290	0.31603774
788532	taxon:9606	3.37135655	3.81E-06	177488	1902	SPARC/osteonectin, cwcv and kazal like domains proteoglycan 1	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0022008-&&-neurogenesis-%%-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0001764-&&-neuron migration-%%-GO:0007165-&&-signal transduction-%%-GO:0010812-&&-negative regulation of cell-substrate adhesion-%%-GO:0010977-&&-negative regulation of neuron projection development-%%-GO:0021953-&&-central nervous system neuron differentiation-%%-GO:0007399-&&-nervous system development|cellular_component-&-1&-GO:0016528-&&-sarcoplasm-%%-GO:0033268-&&-node of Ranvier-%%-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0014069-&&-postsynaptic density-%%-GO:0031594-&&-neuromuscular junction-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0004869-&&-cysteine-type endopeptidase inhibitor activity	G:9606:SPOCK1				SPOCK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPOCK1	0.29661651	0.16666667	4	5	FALSE	SPOCK1	SPOCK1	50.5	0	4	0	0.60477391	FALSE	0	SPOCK1	3078	0.28248588
788549	taxon:9606	2.96013865	1.48E-06	177459	1902	src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites	gene	biological_process-&-1&-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0030154-&&-cell differentiation-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:SRMS				SRMS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SRMS	0.33782201	0	4	5	FALSE	SRMS	SRMS	195	0	4	0	0.67331023	FALSE	0	SRMS	2578	0.28238719
788609	taxon:9606	3.13990862	4.90E-07	160952	1902	keratin 27	gene	biological_process-&-1&-GO:0031069-&&-hair follicle morphogenesis-%%-GO:0031424-&&-keratinization-%%-GO:0070268-&&-cornification-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005882-&&-intermediate filament|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0003674-&&-molecular_function	G:9606:KRT27			KEGG-&-1&-hsa04915-&&-Estrogen signaling pathway	KRT27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRT27	0.31848061	0.33333333	4	5	FALSE	KRT27	KRT27	51.5	0	4	0	0.64334856	FALSE	0	KRT27	316	0.3125
788610	taxon:9606	2.78320466	1.60E-07	160940	1902	non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)	gene	biological_process-&-1&-GO:0008284-&&-positive regulation of cell proliferation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome	G:9606:NCCRP1				NCCRP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCCRP1	0.35929805	0.33333333	4	4	FALSE	NCCRP1	NCCRP1	508.75	0	4	0	0.70279922	FALSE	0	NCCRP1	850	0.32512788
788693	taxon:9606	2.99558847	2.80E-07	177171	1902	TNF alpha induced protein 2	gene	biological_process-&-1&-GO:0006887-&&-exocytosis-%%-GO:0051601-&&-exocyst localization-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0000145-&&-exocyst-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0000149-&&-SNARE binding	G:9606:TNFAIP2				TNFAIP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFAIP2	0.33382423	0	4	5	FALSE	TNFAIP2	TNFAIP2	187.25	0	4	0	0.66740192	FALSE	0	TNFAIP2	886	0.28435115
788751	taxon:9606	2.91649598	3.80E-07	177017	1902	zinc finger protein 121	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF121				ZNF121	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF121	0.34287721	0	4	4	FALSE	ZNF121	ZNF121	261.75	0	4	0	0.680584	FALSE	0	ZNF121	1382	0.27887701
788778	taxon:9606	3.51126516	6.20E-07	176916	1902	interleukin 1 receptor type 2	gene	biological_process-&-1&-GO:0010955-&&-negative regulation of protein processing-%%-GO:0050712-&&-negative regulation of interleukin-1 alpha secretion-%%-GO:1900016-&&-negative regulation of cytokine production involved in inflammatory response-%%-GO:0006955-&&-immune response-%%-GO:2000660-&&-negative regulation of interleukin-1-mediated signaling pathway-%%-GO:0019221-&&-cytokine-mediated signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004908-&&-interleukin-1 receptor activity-%%-GO:0019966-&&-interleukin-1 binding-%%-GO:0005515-&&-protein binding-%%-GO:0004910-&&-interleukin-1, Type II, blocking receptor activity	G:9606:IL1R2			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa05146-&&-Amoebiasis-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa05166-&&-Human T-cell leukemia virus 1 infection-%%-hsa04640-&&-Hematopoietic cell lineage-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL1R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL1R2	0.28479763	0.33333333	4	5	FALSE	IL1R2	IL1R2	12.25	0	4	0	0.58145581	FALSE	0	IL1R2	792	0.3
788867	taxon:9606	3.42744604	0	176734	1902	vascular endothelial growth factor C	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0043536-&&-positive regulation of blood vessel endothelial cell migration-%%-GO:0048010-&&-vascular endothelial growth factor receptor signaling pathway-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0050714-&&-positive regulation of protein secretion-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0007165-&&-signal transduction-%%-GO:0002576-&&-platelet degranulation-%%-GO:0050930-&&-induction of positive chemotaxis-%%-GO:0001954-&&-positive regulation of cell-matrix adhesion-%%-GO:0006929-&&-substrate-dependent cell migration-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:0060754-&&-positive regulation of mast cell chemotaxis-%%-GO:0001666-&&-response to hypoxia-%%-GO:0002052-&&-positive regulation of neuroblast proliferation-%%-GO:0050918-&&-positive chemotaxis-%%-GO:1901492-&&-positive regulation of lymphangiogenesis-%%-GO:0031954-&&-positive regulation of protein autophosphorylation-%%-GO:0016331-&&-morphogenesis of embryonic epithelium-%%-GO:0030947-&&-regulation of vascular endothelial growth factor receptor signaling pathway-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0001938-&&-positive regulation of endothelial cell proliferation-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0031093-&&-platelet alpha granule lumen-%%-GO:0005576-&&-extracellular region-%%-GO:0016020-&&-membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0042056-&&-chemoattractant activity-%%-GO:0043185-&&-vascular endothelial growth factor receptor 3 binding	G:9606:VEGFC			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04015-&&-Rap1 signaling pathway-%%-hsa04668-&&-TNF signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa04933-&&-AGE-RAGE signaling pathway in diabetic complications-%%-hsa05200-&&-Pathways in cancer-%%-hsa04926-&&-Relaxin signaling pathway	VEGFC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VEGFC	0.29176243	1	4	5	FALSE	VEGFC	VEGFC	46.5	0	3	0	0.59542566	FALSE	1	VEGFC	0	0.54069767
788956	taxon:9606	3.10524657	2.50E-07	176533	1902	PTPRF interacting protein alpha 4	gene	biological_process-&-1&-GO:0014047-&&-glutamate secretion-%%-GO:0007269-&&-neurotransmitter secretion|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005829-&&-cytosol-%%-GO:0045202-&&-synapse-%%-GO:0048786-&&-presynaptic active zone-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PPFIA4				PPFIA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPFIA4	0.32203562	0.33333333	4	5	FALSE	PPFIA4	PPFIA4	90.25	0	4	0	0.64912557	FALSE	0	PPFIA4	432	0.26706231
789001	taxon:9606	3.20245785	1.17E-06	160039	1902	natural killer cell cytotoxicity receptor 3 ligand 1	gene	biological_process-&-1&-GO:0050776-&&-regulation of immune response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0019028-&&-viral capsid|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:NCR3LG1				NCR3LG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NCR3LG1	0.31226016	0	4	5	FALSE	NCR3LG1	NCR3LG1	60.25	0	4	0	0.63292369	FALSE	0	NCR3LG1	1498	0.27054795
789050	taxon:9606	2.90058295	2.49E-06	176285	1902	regulator of G-protein signaling 9	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0006457-&&-protein folding-%%-GO:0007212-&&-dopamine receptor signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0043627-&&-response to estrogen-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0007601-&&-visual perception|cellular_component-&-1&-GO:0001917-&&-photoreceptor inner segment-%%-GO:0005834-&&-heterotrimeric G-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0097381-&&-photoreceptor disc membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0005096-&&-GTPase activator activity-%%-GO:0004871-&&-signal transducer activity	G:9606:RGS9			KEGG-&-1&-hsa04744-&&-Phototransduction-%%-hsa05030-&&-Cocaine addiction	RGS9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS9	0.34475828	0	4	5	FALSE	RGS9	RGS9	240	0	4	0	0.68323617	FALSE	0	RGS9	5144	0.26674107
789137	taxon:9606	2.81818182	1.59E-06	176128	1902	cyclin dependent kinase like 2	gene	biological_process-&-1&-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0007548-&&-sex differentiation-%%-GO:0051726-&&-regulation of cell cycle-%%-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004693-&&-cyclin-dependent protein serine/threonine kinase activity-%%-GO:0004672-&&-protein kinase activity	G:9606:CDKL2				CDKL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CDKL2	0.35483871	0.16666667	4	5	FALSE	CDKL2	CDKL2	375.5	0	4	0	0.6969697	FALSE	0	CDKL2	2688	0.2755327
789282	taxon:9606	2.76933985	3.60E-07	175829	1902	stomatin like 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:STOML1				STOML1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STOML1	0.36109689	0.33333333	4	5	FALSE	STOML1	STOML1	472.75	0	4	0	0.70511003	FALSE	0	STOML1	1302	0.28601695
789334	taxon:9606	3.38175516	1.90E-07	175709	1902	TNF receptor superfamily member 6b	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0033209-&&-tumor necrosis factor-mediated signaling pathway-%%-GO:0006955-&&-immune response-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0005031-&&-tumor necrosis factor-activated receptor activity	G:9606:TNFRSF6B			KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction	TNFRSF6B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNFRSF6B	0.29570444	0.5	4	5	FALSE	TNFRSF6B	TNFRSF6B	72	0	4	0	0.60304081	FALSE	0	TNFRSF6B	336	0.42455621
789421	taxon:9606	3.13470931	8.30E-07	175517	1902	transmembrane protein 94	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMEM94				TMEM94	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM94	0.31900885	0.16666667	4	5	FALSE	TMEM94	TMEM94	69.25	0	4	0	0.64421511	FALSE	0	TMEM94	994	0.26750973
789750	taxon:9606	2.93240901	1.39E-06	174769	1902	tetraspanin 2	gene	biological_process-&-1&-GO:0014002-&&-astrocyte development-%%-GO:0014005-&&-microglia development-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0006954-&&-inflammatory response-%%-GO:0007420-&&-brain development-%%-GO:0048709-&&-oligodendrocyte differentiation-%%-GO:0061564-&&-axon development-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043209-&&-myelin sheath|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TSPAN2				TSPAN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSPAN2	0.34101655	0.16666667	4	5	FALSE	TSPAN2	TSPAN2	227.5	0	4	0	0.67793183	FALSE	0	TSPAN2	2798	0.27448609
789816	taxon:9606	2.82684733	1.60E-07	158210	1902	YY2 transcription factor	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:YY2				YY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YY2	0.35375098	0.66666667	4	4	FALSE	YY2	YY2	402.5	0	4	0	0.69552545	FALSE	0	YY2	528	0.28936017
789821	taxon:9606	3.48479597	2.77E-06	174567	1902	lymphatic vessel endothelial hyaluronan receptor 1	gene	biological_process-&-1&-GO:0030214-&&-hyaluronan catabolic process-%%-GO:0009611-&&-response to wounding-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007165-&&-signal transduction-%%-GO:0006810-&&-transport-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0007160-&&-cell-matrix adhesion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0005540-&&-hyaluronic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:LYVE1				LYVE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LYVE1	0.28696085	0.16666667	4	5	FALSE	LYVE1	LYVE1	52	0	4	0	0.58586734	FALSE	0	LYVE1	1594	0.35034014
789823	taxon:9606	2.92437372	1.17E-06	174557	1902	bladder cancer associated protein	gene	biological_process-&-1&-GO:0007049-&&-cell cycle-%%-GO:0030262-&&-apoptotic nuclear changes|cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:BLCAP				BLCAP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BLCAP	0.34195356	0	4	5	FALSE	BLCAP	BLCAP	262.5	0	4	0	0.67927105	FALSE	0	BLCAP	5088	0.30946746
789875	taxon:9606	2.73625335	1.80E-07	174463	1902	SPEG complex locus	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007517-&&-muscle organ development-%%-GO:0042692-&&-muscle cell differentiation-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:SPEG				SPEG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPEG	0.36546323	0.33333333	4	4	FALSE	SPEG	SPEG	530	0	4	0	0.71062444	FALSE	0	SPEG	842	0.29075192
790012	taxon:9606	2.94170474	4.28E-06	174112	1902	neuraminidase 3	gene	biological_process-&-1&-GO:0006689-&&-ganglioside catabolic process-%%-GO:0009313-&&-oligosaccharide catabolic process-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0052796-&&-exo-alpha-(2->8)-sialidase activity-%%-GO:0052795-&&-exo-alpha-(2->6)-sialidase activity-%%-GO:0016997-&&-alpha-sialidase activity-%%-GO:0052794-&&-exo-alpha-(2->3)-sialidase activity-%%-GO:0004308-&&-exo-alpha-sialidase activity	G:9606:NEU3			KEGG-&-1&-hsa00511-&&-Other glycan degradation-%%-hsa00600-&&-Sphingolipid metabolism	NEU3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEU3	0.33993894	0	4	5	FALSE	NEU3	NEU3	199.75	0	4	0	0.67638254	FALSE	0	NEU3	3598	0.26821862
790211	taxon:9606	2.92043485	1.34E-06	173629	1902	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	gene	biological_process-&-1&-GO:1990090-&&-cellular response to nerve growth factor stimulus-%%-GO:0036010-&&-protein localization to endosome-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0010008-&&-endosome membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:ACAP2			KEGG-&-1&-hsa04144-&&-Endocytosis	ACAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACAP2	0.34241476	0	4	5	FALSE	ACAP2	ACAP2	243	0	4	0	0.67992752	FALSE	0	ACAP2	1876	0.27594071
790227	taxon:9606	2.95667244	2.40E-07	173581	1902	DENN domain containing 5A	gene	biological_process-&-1&-GO:0061024-&&-membrane organization-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0030904-&&-retromer complex-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0017112-&&-Rab guanyl-nucleotide exchange factor activity-%%-GO:0017137-&&-Rab GTPase binding-%%-GO:0005262-&&-calcium channel activity	G:9606:DENND5A				DENND5A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DENND5A	0.33821805	0.16666667	4	4	FALSE	DENND5A	DENND5A	181.25	0	4	0	0.67388793	FALSE	0	DENND5A	604	0.27850539
790360	taxon:9606	3.08980621	1.26E-06	173222	1902	solute carrier family 39 member 14	gene	biological_process-&-1&-GO:1903874-&&-ferrous iron transmembrane transport-%%-GO:0006882-&&-cellular zinc ion homeostasis-%%-GO:0071577-&&-zinc II ion transmembrane transport-%%-GO:0071578-&&-zinc II ion transmembrane import|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030027-&&-lamellipodium-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005385-&&-zinc ion transmembrane transporter activity-%%-GO:0015093-&&-ferrous iron transmembrane transporter activity	G:9606:SLC39A14	SLC39A14	TRUE	KEGG-&-1&-hsa04216-&&-Ferroptosis	SLC39A14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC39A14	0.32364489	0	4	5	FALSE	SLC39A14	SLC39A14	153	0	4	0	0.65169897	FALSE	0	SLC39A14	2550	0.30769231
790408	taxon:9606	2.89144478	4.20E-07	173090	1902	potassium voltage-gated channel subfamily E regulatory subunit 4	gene	biological_process-&-1&-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005515-&&-protein binding-%%-GO:0005249-&&-voltage-gated potassium channel activity	G:9606:KCNE4				KCNE4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNE4	0.34584786	0.33333333	4	4	FALSE	KCNE4	KCNE4	272.75	0	4	0	0.6847592	FALSE	0	KCNE4	808	0.28179938
790510	taxon:9606	2.85883094	1.20E-07	172654	1902	F-box protein 8	gene	biological_process-&-1&-GO:0032012-&&-regulation of ARF protein signal transduction-%%-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex|molecular_function-&-1&-GO:0005086-&&-ARF guanyl-nucleotide exchange factor activity	G:9606:FBXO8				FBXO8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO8	0.34979333	0.5	4	4	FALSE	FBXO8	FBXO8	357	0	4	0	0.69019484	FALSE	0	FBXO8	558	0.30258694
790526	taxon:9606	3.02253033	1.61E-06	172596	1902	NFU1 iron-sulfur cluster scaffold	gene	biological_process-&-1&-GO:0016226-&&-iron-sulfur cluster assembly|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0051539-&&-4 iron, 4 sulfur cluster binding-%%-GO:0005515-&&-protein binding-%%-GO:0005506-&&-iron ion binding	G:9606:NFU1	NFU1	TRUE		NFU1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFU1	0.33084862	0	4	5	FALSE	NFU1	NFU1	140.5	0	4	0	0.66291161	FALSE	0	NFU1	1886	0.26026119
790543	taxon:9606	2.74176776	4.58E-06	172538	1902	transmembrane protein 97	gene	biological_process-&-1&-GO:0042632-&&-cholesterol homeostasis-%%-GO:0001558-&&-regulation of cell growth|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005764-&&-lysosome-%%-GO:0005791-&&-rough endoplasmic reticulum|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TMEM97				TMEM97	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM97	0.36472819	0.16666667	4	5	FALSE	TMEM97	TMEM97	495.5	0	4	0	0.70970537	FALSE	0	TMEM97	4698	0.2784027
790581	taxon:9606	2.97809989	2.80E-07	172081	1902	MDM2 binding protein	gene	biological_process-&-1&-GO:0007089-&&-traversing start control point of mitotic cell cycle-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0045839-&&-negative regulation of mitotic nuclear division-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0034501-&&-protein localization to kinetochore|cellular_component-&-1&-GO:0000776-&&-kinetochore-%%-GO:0000785-&&-chromatin	G:9606:MTBP				MTBP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTBP	0.33578457	0	4	5	FALSE	MTBP	MTBP	175.75	0	4	0	0.67031669	FALSE	0	MTBP	782	0.26967593
790664	taxon:9606	2.70805105	4.50E-07	171554	1902	adipogenesis associated Mth938 domain containing	gene	biological_process-&-1&-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0045600-&&-positive regulation of fat cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:AAMDC				AAMDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AAMDC	0.36926926	0.5	4	4	FALSE	AAMDC	AAMDC	571.5	0	4	0	0.71532483	FALSE	0	AAMDC	1954	0.29113602
790698	taxon:9606	3.37167166	9.10E-07	171432	1902	inducible T-cell costimulator	gene	biological_process-&-1&-GO:0031295-&&-T cell costimulation-%%-GO:0002517-&&-T cell tolerance induction-%%-GO:0006955-&&-immune response-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0016337-&&-single organismal cell-cell adhesion-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005886-&&-plasma membrane-%%-GO:0009897-&&-external side of plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity	G:9606:ICOS			KEGG-&-1&-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05340-&&-Primary immunodeficiency-%%-hsa04660-&&-T cell receptor signaling pathway	ICOS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ICOS	0.29658879	0	4	5	FALSE	ICOS	ICOS	63	0	3	0	0.60472139	FALSE	1	ICOS	254	0.5
790758	taxon:9606	3.21411691	9.70E-07	171309	1902	tubulin epsilon 1	gene	biological_process-&-1&-GO:0007098-&&-centrosome cycle|cellular_component-&-1&-GO:0000242-&&-pericentriolar material-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005200-&&-structural constituent of cytoskeleton-%%-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:TUBE1				TUBE1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TUBE1	0.31112745	0.16666667	4	5	FALSE	TUBE1	TUBE1	146.25	0	4	0	0.63098052	FALSE	0	TUBE1	1168	0.4810231
790815	taxon:9606	3.10477391	1.01E-06	171124	1902	S-phase cyclin A associated protein in the ER	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003676-&&-nucleic acid binding	G:9606:SCAPER				SCAPER	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCAPER	0.32208464	0	4	5	FALSE	SCAPER	SCAPER	95	0	4	0	0.64920435	FALSE	0	SCAPER	1276	0.26478873
790984	taxon:9606	3.07011186	7.00E-08	170497	1902	piwi like RNA-mediated gene silencing 2	gene	biological_process-&-1&-GO:0000966-&&-RNA 5'-end processing-%%-GO:0031047-&&-gene silencing by RNA-%%-GO:0043046-&&-DNA methylation involved in gamete generation-%%-GO:0090502-&&-RNA phosphodiester bond hydrolysis, endonucleolytic-%%-GO:0060903-&&-positive regulation of meiosis I-%%-GO:0051321-&&-meiotic cell cycle-%%-GO:0007275-&&-multicellular organism development-%%-GO:0010529-&&-negative regulation of transposition-%%-GO:0045727-&&-positive regulation of translation-%%-GO:0030718-&&-germ-line stem cell population maintenance-%%-GO:0071442-&&-positive regulation of histone H3-K14 acetylation-%%-GO:0034587-&&-piRNA metabolic process-%%-GO:0007283-&&-spermatogenesis-%%-GO:0048477-&&-oogenesis-%%-GO:2000617-&&-positive regulation of histone H3-K9 acetylation|cellular_component-&-1&-GO:1990923-&&-PET complex-%%-GO:0043186-&&-P granule-%%-GO:0033391-&&-chromatoid body-%%-GO:0005737-&&-cytoplasm-%%-GO:0010370-&&-perinucleolar chromocenter-%%-GO:0005844-&&-polysome-%%-GO:0097433-&&-dense body-%%-GO:0071546-&&-pi-body|molecular_function-&-1&-GO:0034584-&&-piRNA binding-%%-GO:0003729-&&-mRNA binding-%%-GO:0004521-&&-endoribonuclease activity	G:9606:PIWIL2				PIWIL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIWIL2	0.32572103	0.5	4	5	FALSE	PIWIL2	PIWIL2	105	0	4	0	0.65498136	FALSE	0	PIWIL2	196	0.31268657
791061	taxon:9606	2.97683945	3.60E-07	170193	1902	zinc finger protein 280C	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZNF280C				ZNF280C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF280C	0.33592675	0	4	5	FALSE	ZNF280C	ZNF280C	153.25	0	4	0	0.67052676	FALSE	0	ZNF280C	748	0.26114923
791106	taxon:9606	2.86087916	4.60E-07	170020	1902	F-box and leucine rich repeat protein 8	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXL8				FBXL8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL8	0.3495429	0.5	4	5	FALSE	FBXL8	FBXL8	348.75	0	4	0	0.68985347	FALSE	0	FBXL8	900	0.30410122
791175	taxon:9606	2.76870963	5.70E-07	169823	1902	kelch repeat and BTB domain containing 4	gene	biological_process-&-1&-GO:0030162-&&-regulation of proteolysis-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0043161-&&-proteasome-mediated ubiquitin-dependent protein catabolic process|cellular_component-&-1&-GO:0019005-&&-SCF ubiquitin ligase complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0031625-&&-ubiquitin protein ligase binding	G:9606:KBTBD4				KBTBD4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KBTBD4	0.36117908	0.33333333	4	4	FALSE	KBTBD4	KBTBD4	560.5	0	4	0	0.70521506	FALSE	0	KBTBD4	1632	0.3403706
791199	taxon:9606	2.83551284	4.80E-07	169747	1902	methyltransferase like 2B	gene	biological_process-&-1&-GO:0030488-&&-tRNA methylation|molecular_function-&-1&-GO:0016427-&&-tRNA (cytosine) methyltransferase activity	G:9606:METTL2B				METTL2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL2B	0.35266989	0.5	4	5	FALSE	METTL2B	METTL2B	354.75	0	4	0	0.69408119	FALSE	0	METTL2B	1714	0.27673692
791203	taxon:9606	2.79454861	2.14E-06	169732	1902	translin associated factor X interacting protein 1	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0008150-&&-biological_process-%%-GO:0030154-&&-cell differentiation-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TSNAXIP1				TSNAXIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TSNAXIP1	0.35783954	0	4	4	FALSE	TSNAXIP1	TSNAXIP1	399.25	0	4	0	0.70090857	FALSE	0	TSNAXIP1	8072	0.271843
791217	taxon:9606	2.86466047	3.90E-07	169704	1902	prostate transmembrane protein, androgen induced 1	gene	biological_process-&-1&-GO:0030521-&&-androgen receptor signaling pathway-%%-GO:0030512-&&-negative regulation of transforming growth factor beta receptor signaling pathway-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0010991-&&-negative regulation of SMAD protein complex assembly|cellular_component-&-1&-GO:0031901-&&-early endosome membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0010008-&&-endosome membrane|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0050699-&&-WW domain binding-%%-GO:0070412-&&-R-SMAD binding	G:9606:PMEPA1				PMEPA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PMEPA1	0.34908151	0	4	5	FALSE	PMEPA1	PMEPA1	299.75	0	4	0	0.68922326	FALSE	0	PMEPA1	1478	0.27060688
791219	taxon:9606	3.01417993	0	169702	1902	dual specificity phosphatase 22	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0008283-&&-cell proliferation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0050860-&&-negative regulation of T cell receptor signaling pathway-%%-GO:0002710-&&-negative regulation of T cell mediated immunity-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0046330-&&-positive regulation of JNK cascade-%%-GO:0050868-&&-negative regulation of T cell activation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity	G:9606:DUSP22				DUSP22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP22	0.3317652	1	4	5	FALSE	DUSP22	DUSP22	132.25	0	4	0	0.66430335	FALSE	0	DUSP22	0	0.30827506
791248	taxon:9606	3.01339215	4.00E-08	169542	1902	leukotriene B4 receptor 2	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0051546-&&-keratinocyte migration-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0061737-&&-leukotriene signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0008528-&&-G-protein coupled peptide receptor activity-%%-GO:0001632-&&-leukotriene B4 receptor activity-%%-GO:0004974-&&-leukotriene receptor activity	G:9606:LTB4R2			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	LTB4R2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LTB4R2	0.33185193	0	4	5	FALSE	LTB4R2	LTB4R2	215	0	3	0	0.66443464	FALSE	1	LTB4R2	104	0.5245098
791268	taxon:9606	2.87679219	1.60E-07	169429	1902	aryl-hydrocarbon receptor repressor	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0009410-&&-response to xenobiotic stimulus-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0034753-&&-nuclear aryl hydrocarbon receptor complex|molecular_function-&-1&-GO:0001191-&&-transcriptional repressor activity, RNA polymerase II transcription factor binding-%%-GO:0003677-&&-DNA binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:AHRR				AHRR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHRR	0.3476094	0.66666667	4	5	FALSE	AHRR	AHRR	321	0	4	0	0.6872013	FALSE	0	AHRR	424	0.30571429
791281	taxon:9606	2.94989759	3.45E-06	169368	1902	kelch like family member 14	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016235-&&-aggresome-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL14				KLHL14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL14	0.33899482	0.33333333	4	5	FALSE	KLHL14	KLHL14	187.5	0	4	0	0.67501707	FALSE	0	KLHL14	1658	0.2671184
791344	taxon:9606	3.14888924	1.32E-06	169074	1902	nyctalopin	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005622-&&-intracellular-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0004860-&&-protein kinase inhibitor activity	G:9606:NYX				NYX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NYX	0.3175723	0	4	5	FALSE	NYX	NYX	44.25	0	4	0	0.64185179	FALSE	0	NYX	1168	0.25744048
791391	taxon:9606	3.05104774	1.31E-06	168825	1902	MID1 interacting protein 1	gene	biological_process-&-1&-GO:0045723-&&-positive regulation of fatty acid biosynthetic process-%%-GO:0046890-&&-regulation of lipid biosynthetic process-%%-GO:0051258-&&-protein polymerization-%%-GO:0051351-&&-positive regulation of ligase activity-%%-GO:0007026-&&-negative regulation of microtubule depolymerization-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0006853-&&-carnitine shuttle|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005634-&&-nucleus-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0008022-&&-protein C-terminus binding-%%-GO:0005515-&&-protein binding	G:9606:MID1IP1				MID1IP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MID1IP1	0.32775626	0.16666667	4	5	FALSE	MID1IP1	MID1IP1	117.25	0	4	0	0.65815871	FALSE	0	MID1IP1	1364	0.26716247
791410	taxon:9606	2.94075941	1.00E-08	168755	1902	EF-hand calcium binding domain 6	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:EFCAB6				EFCAB6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EFCAB6	0.34004822	0.83333333	4	5	FALSE	EFCAB6	EFCAB6	251.75	0	4	0	0.6765401	FALSE	0	EFCAB6	26	0.32358612
791447	taxon:9606	3.18749015	1.50E-06	168605	1902	Yip1 domain family member 2	gene	cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:YIPF2				YIPF2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-YIPF2	0.31372646	0	4	5	FALSE	YIPF2	YIPF2	56.75	0	4	0	0.63541831	FALSE	0	YIPF2	1170	0.25456621
791482	taxon:9606	3.14841657	4.20E-07	168454	1902	anoctamin 3	gene	biological_process-&-1&-GO:0061591-&&-calcium activated galactosylceramide scrambling-%%-GO:0050982-&&-detection of mechanical stimulus-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0016048-&&-detection of temperature stimulus-%%-GO:0061590-&&-calcium activated phosphatidylcholine scrambling-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0006869-&&-lipid transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0046983-&&-protein dimerization activity-%%-GO:0005229-&&-intracellular calcium activated chloride channel activity-%%-GO:0017128-&&-phospholipid scramblase activity	G:9606:ANO3				ANO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANO3	0.31761998	0	4	5	FALSE	ANO3	ANO3	62	0	4	0	0.64193057	FALSE	0	ANO3	468	0.25311203
791513	taxon:9606	2.80163857	4.20E-07	168330	1902	kelch like family member 25	gene	biological_process-&-1&-GO:0006446-&&-regulation of translational initiation-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0031463-&&-Cul3-RING ubiquitin ligase complex	G:9606:KLHL25				KLHL25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL25	0.35693398	0.5	4	4	FALSE	KLHL25	KLHL25	416.5	0	4	0	0.69972691	FALSE	0	KLHL25	1212	0.28449454
791514	taxon:9606	2.8307862	9.40E-07	168324	1902	sushi domain containing 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005509-&&-calcium ion binding	G:9606:SUSD1				SUSD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SUSD1	0.35325875	0.33333333	4	4	FALSE	SUSD1	SUSD1	373.75	0	4	0	0.69486897	FALSE	0	SUSD1	1912	0.28381459
791570	taxon:9606	2.97069482	1.82E-06	167965	1902	UDP-glucuronate decarboxylase 1	gene	biological_process-&-1&-GO:0033320-&&-UDP-D-xylose biosynthetic process-%%-GO:0051262-&&-protein tetramerization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity-%%-GO:0070403-&&-NAD+ binding-%%-GO:0048040-&&-UDP-glucuronate decarboxylase activity	G:9606:UXS1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism	UXS1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UXS1	0.33662159	0	4	5	FALSE	UXS1	UXS1	168.75	0	4	0	0.67155086	FALSE	0	UXS1	2358	0.2633438
791616	taxon:9606	3.03686781	1.46E-06	167796	1902	MOB kinase activator 3B	gene	molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005515-&&-protein binding	G:9606:MOB3B				MOB3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MOB3B	0.32928664	0.16666667	4	5	FALSE	MOB3B	MOB3B	108.25	0	4	0	0.66052203	FALSE	0	MOB3B	1088	0.27987013
791731	taxon:9606	2.99606113	3.70E-07	167136	1902	BCL2 like 12	gene	biological_process-&-1&-GO:2000773-&&-negative regulation of cellular senescence-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006915-&&-apoptotic process-%%-GO:1990001-&&-inhibition of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0002039-&&-p53 binding	G:9606:BCL2L12				BCL2L12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BCL2L12	0.33377156	0.5	4	5	FALSE	BCL2L12	BCL2L12	140.75	0	4	0	0.66732314	FALSE	0	BCL2L12	666	0.2872449
791814	taxon:9606	3.00425398	5.80E-07	166748	1902	KRAB-A domain containing 1	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:KRBA1				KRBA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KRBA1	0.33286134	0	4	5	FALSE	KRBA1	KRBA1	145.25	0	4	0	0.66595767	FALSE	0	KRBA1	956	0.29024145
791858	taxon:9606	3.29021585	1.27E-06	166586	1902	transmembrane and tetratricopeptide repeat containing 4	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMTC4				TMTC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMTC4	0.30393143	0	4	5	FALSE	TMTC4	TMTC4	37.5	0	4	0	0.61829736	FALSE	0	TMTC4	806	0.25524476
791900	taxon:9606	3.03734048	3.00E-07	166526	1902	autophagy related 4D cysteine peptidase	gene	biological_process-&-1&-GO:0044804-&&-nucleophagy-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0006915-&&-apoptotic process-%%-GO:0000422-&&-mitophagy-%%-GO:0051697-&&-protein delipidation-%%-GO:0006508-&&-proteolysis-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0006612-&&-protein targeting to membrane|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004197-&&-cysteine-type endopeptidase activity	G:9606:ATG4D			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04136-&&-Autophagy - other	ATG4D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATG4D	0.3292354	0.33333333	4	5	FALSE	ATG4D	ATG4D	128.25	0	4	0	0.66044325	FALSE	0	ATG4D	618	0.31823821
791916	taxon:9606	2.7346778	7.03E-06	182880	1902	adenylate kinase 4	gene	biological_process-&-1&-GO:0046940-&&-nucleoside monophosphate phosphorylation-%%-GO:0046034-&&-ATP metabolic process-%%-GO:0009142-&&-nucleoside triphosphate biosynthetic process-%%-GO:0001889-&&-liver development-%%-GO:0007420-&&-brain development-%%-GO:0046033-&&-AMP metabolic process-%%-GO:0006165-&&-nucleoside diphosphate phosphorylation-%%-GO:0015949-&&-nucleobase-containing small molecule interconversion-%%-GO:0046039-&&-GTP metabolic process-%%-GO:0042493-&&-response to drug|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046899-&&-nucleoside triphosphate adenylate kinase activity-%%-GO:0005525-&&-GTP binding-%%-GO:0050145-&&-nucleoside phosphate kinase activity-%%-GO:0004017-&&-adenylate kinase activity-%%-GO:0004550-&&-nucleoside diphosphate kinase activity	G:9606:AK4			KEGG-&-1&-hsa00730-&&-Thiamine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00230-&&-Purine metabolism	AK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AK4	0.36567379	0.33333333	4	5	FALSE	AK4	AK4	507.25	0	4	0	0.71088703	FALSE	0	AK4	4774	0.27995583
791942	taxon:9606	2.91066646	3.48E-06	182829	1902	anti-Mullerian hormone receptor type 2	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:1990262-&&-anti-Mullerian hormone signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0007548-&&-sex differentiation-%%-GO:0008585-&&-female gonad development-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:1902613-&&-negative regulation of anti-Mullerian hormone signaling pathway-%%-GO:0001880-&&-Mullerian duct regression|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004872-&&-receptor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0042562-&&-hormone binding-%%-GO:1990272-&&-anti-Mullerian hormone receptor activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005026-&&-transforming growth factor beta receptor activity, type II	G:9606:AMHR2	AMHR2	TRUE	KEGG-&-1&-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	AMHR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMHR2	0.34356393	0.16666667	4	5	FALSE	AMHR2	AMHR2	252.5	0	4	0	0.68155559	FALSE	0	AMHR2	2060	0.29893238
791944	taxon:9606	2.79706948	7.46E-06	182830	1902	anti-Mullerian hormone	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0001880-&&-Mullerian duct regression-%%-GO:0007548-&&-sex differentiation-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:2000355-&&-negative regulation of ovarian follicle development-%%-GO:0007530-&&-sex determination-%%-GO:0001546-&&-preantral ovarian follicle growth-%%-GO:0001655-&&-urogenital system development-%%-GO:0042493-&&-response to drug-%%-GO:0007506-&&-gonadal mesoderm development-%%-GO:0007568-&&-aging|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008083-&&-growth factor activity-%%-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0005179-&&-hormone activity-%%-GO:0005102-&&-receptor binding	G:9606:AMH	AMH	TRUE	KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	AMH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AMH	0.35751704	0	4	4	FALSE	AMH	AMH	392.25	0	4	0	0.70048842	FALSE	0	AMH	5638	0.26742994
792009	taxon:9606	2.88813613	2.15E-06	166355	1902	myosin light chain kinase 3	gene	biological_process-&-1&-GO:0055003-&&-cardiac myofibril assembly-%%-GO:0048769-&&-sarcomerogenesis-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0045214-&&-sarcomere organization-%%-GO:0060298-&&-positive regulation of sarcomere organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0018105-&&-peptidyl-serine phosphorylation-%%-GO:0002528-&&-regulation of vascular permeability involved in acute inflammatory response-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005829-&&-cytosol-%%-GO:0015629-&&-actin cytoskeleton-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004687-&&-myosin light chain kinase activity-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity	G:9606:MYLK3			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04510-&&-Focal adhesion-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04971-&&-Gastric acid secretion-%%-hsa04810-&&-Regulation of actin cytoskeleton-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04022-&&-cGMP-PKG signaling pathway	MYLK3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYLK3	0.34624407	0	4	4	FALSE	MYLK3	MYLK3	255	0	4	0	0.68531065	FALSE	0	MYLK3	4812	0.26849894
792056	taxon:9606	3.15014968	1.14E-06	182682	1902	bone marrow stromal cell antigen 1	gene	biological_process-&-1&-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0090322-&&-regulation of superoxide metabolic process-%%-GO:0007165-&&-signal transduction-%%-GO:2001044-&&-regulation of integrin-mediated signaling pathway-%%-GO:0050730-&&-regulation of peptidyl-tyrosine phosphorylation-%%-GO:0019674-&&-NAD metabolic process-%%-GO:0006959-&&-humoral immune response-%%-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0050727-&&-regulation of inflammatory response-%%-GO:0050848-&&-regulation of calcium-mediated signaling-%%-GO:0002691-&&-regulation of cellular extravasation-%%-GO:0090022-&&-regulation of neutrophil chemotaxis-%%-GO:0001952-&&-regulation of cell-matrix adhesion|cellular_component-&-1&-GO:0035579-&&-specific granule membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex-%%-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0001931-&&-uropod|molecular_function-&-1&-GO:0061809-&&-NAD+ nucleotidase, cyclic ADP-ribose generating-%%-GO:0016740-&&-transferase activity-%%-GO:0061811-&&-ADP-ribosyl cyclase activity-%%-GO:0003953-&&-NAD+ nucleosidase activity-%%-GO:0061812-&&-cyclic ADP-ribose hydrolase-%%-GO:0050135-&&-NAD(P)+ nucleosidase activity	G:9606:BST1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04972-&&-Pancreatic secretion-%%-hsa04970-&&-Salivary secretion-%%-hsa00760-&&-Nicotinate and nicotinamide metabolism	BST1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BST1	0.31744523	0	4	5	FALSE	BST1	BST1	107	0	3	0	0.64164172	FALSE	1	BST1	482	0.5
792064	taxon:9606	2.78698598	1.42E-05	182671	1902	butyrophilin subfamily 1 member A1	gene	cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004872-&&-receptor activity	G:9606:BTN1A1				BTN1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BTN1A1	0.35881056	0.16666667	4	4	FALSE	BTN1A1	BTN1A1	414	0	4	0	0.702169	FALSE	0	BTN1A1	9152	0.26055451
792146	taxon:9606	3.23916811	7.20E-07	166139	1902	transmembrane protein 263	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMEM263				TMEM263	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM263	0.30872124	0	4	5	FALSE	TMEM263	TMEM263	47.75	0	4	0	0.62680531	FALSE	0	TMEM263	610	0.25407609
792200	taxon:9606	2.9153931	1.04E-05	182443	1902	arylsulfatase B	gene	biological_process-&-1&-GO:0030207-&&-chondroitin sulfate catabolic process-%%-GO:0007040-&&-lysosome organization-%%-GO:0007041-&&-lysosomal transport-%%-GO:0043687-&&-post-translational protein modification-%%-GO:0061580-&&-colon epithelial cell migration-%%-GO:0010632-&&-regulation of epithelial cell migration-%%-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0043627-&&-response to estrogen-%%-GO:0006914-&&-autophagy-%%-GO:0009268-&&-response to pH-%%-GO:0007417-&&-central nervous system development-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0006687-&&-glycosphingolipid metabolic process-%%-GO:0007584-&&-response to nutrient-%%-GO:0051597-&&-response to methylmercury|cellular_component-&-1&-GO:1904813-&&-ficolin-1-rich granule lumen-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome-%%-GO:0009986-&&-cell surface-%%-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005739-&&-mitochondrion-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0035578-&&-azurophil granule lumen-%%-GO:0043202-&&-lysosomal lumen|molecular_function-&-1&-GO:0003943-&&-N-acetylgalactosamine-4-sulfatase activity-%%-GO:0004065-&&-arylsulfatase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ARSB			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04142-&&-Lysosome-%%-hsa00531-&&-Glycosaminoglycan degradation	ARSB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARSB	0.34300692	0	4	4	FALSE	ARSB	ARSB	218.75	0	4	0	0.68076782	FALSE	0	ARSB	7998	0.25587544
792229	taxon:9606	2.95147314	5.20E-07	165992	1902	membrane associated ring-CH-type finger 9	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005765-&&-lysosomal membrane-%%-GO:0005795-&&-Golgi stack-%%-GO:0005802-&&-trans-Golgi network|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0016740-&&-transferase activity	G:9606:MARCH9				9-Mar	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MARCH9	0.33881386	0	4	5	FALSE	9-Mar	9-Mar	348	0	3	0	0.67475448	FALSE	1	9-Mar	1130	0.50805271
792292	taxon:9606	3.24247676	5.44E-06	165892	1902	sideroflexin 5	gene	biological_process-&-1&-GO:0015746-&&-citrate transport-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0015137-&&-citrate transmembrane transporter activity	G:9606:SFXN5				SFXN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SFXN5	0.30840622	0.16666667	4	5	FALSE	SFXN5	SFXN5	56.25	0	4	0	0.62625387	FALSE	0	SFXN5	5744	0.26932367
792337	taxon:9606	2.85111076	7.80E-07	165827	1902	melanocortin 2 receptor accessory protein 2	gene	biological_process-&-1&-GO:0034394-&&-protein localization to cell surface-%%-GO:0097009-&&-energy homeostasis-%%-GO:0006112-&&-energy reserve metabolic process-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0007631-&&-feeding behavior|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0031780-&&-corticotropin hormone receptor binding-%%-GO:0070996-&&-type 1 melanocortin receptor binding-%%-GO:0031783-&&-type 5 melanocortin receptor binding-%%-GO:0005515-&&-protein binding-%%-GO:0031781-&&-type 3 melanocortin receptor binding-%%-GO:0042802-&&-identical protein binding-%%-GO:0031782-&&-type 4 melanocortin receptor binding	G:9606:MRAP2				MRAP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MRAP2	0.3507405	0	4	5	FALSE	MRAP2	MRAP2	631	0	3	0	0.69148154	FALSE	1	MRAP2	4754	0.51597052
792378	taxon:9606	3.08381913	4.53E-06	165746	1902	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0001501-&&-skeletal system development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0060021-&&-palate development-%%-GO:0048747-&&-muscle fiber development|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:WFIKKN1				WFIKKN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WFIKKN1	0.32427323	0.33333333	4	5	FALSE	WFIKKN1	WFIKKN1	83.25	0	4	0	0.65269681	FALSE	0	WFIKKN1	4442	0.26265823
792620	taxon:9606	2.93146368	5.90E-07	165323	1902	Sp7 transcription factor	gene	biological_process-&-1&-GO:2000738-&&-positive regulation of stem cell differentiation-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0060218-&&-hematopoietic stem cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0017151-&&-DEAD/H-box RNA helicase binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003677-&&-DNA binding	G:9606:SP7				SP7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SP7	0.34112652	0.16666667	4	4	FALSE	SP7	SP7	209.75	0	4	0	0.67808939	FALSE	0	SP7	1302	0.29347826
792640	taxon:9606	3.1361273	5.60E-07	181662	1902	CD86 molecule	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0034138-&&-toll-like receptor 3 signaling pathway-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0002309-&&-T cell proliferation involved in immune response-%%-GO:0002250-&&-adaptive immune response-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:0045086-&&-positive regulation of interleukin-2 biosynthetic process-%%-GO:0007568-&&-aging-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0042110-&&-T cell activation-%%-GO:0042113-&&-B cell activation-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0071222-&&-cellular response to lipopolysaccharide-%%-GO:0043011-&&-myeloid dendritic cell differentiation-%%-GO:0045630-&&-positive regulation of T-helper 2 cell differentiation-%%-GO:0001878-&&-response to yeast-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0043017-&&-positive regulation of lymphotoxin A biosynthetic process-%%-GO:0006955-&&-immune response-%%-GO:0042104-&&-positive regulation of activated T cell proliferation-%%-GO:0051607-&&-defense response to virus-%%-GO:0042493-&&-response to drug-%%-GO:0045404-&&-positive regulation of interleukin-4 biosynthetic process-%%-GO:0002668-&&-negative regulation of T cell anergy-%%-GO:0031295-&&-T cell costimulation-%%-GO:0071248-&&-cellular response to metal ion|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009897-&&-external side of plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity-%%-GO:0015026-&&-coreceptor activity-%%-GO:0005102-&&-receptor binding	G:9606:CD86			KEGG-&-1&-hsa04620-&&-Toll-like receptor signaling pathway-%%-hsa05320-&&-Autoimmune thyroid disease-%%-hsa05330-&&-Allograft rejection-%%-hsa04514-&&-Cell adhesion molecules (CAMs)-%%-hsa04672-&&-Intestinal immune network for IgA production-%%-hsa05416-&&-Viral myocarditis-%%-hsa05202-&&-Transcriptional misregulation in cancer-%%-hsa04940-&&-Type I diabetes mellitus-%%-hsa05322-&&-Systemic lupus erythematosus-%%-hsa05332-&&-Graft-versus-host disease-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05323-&&-Rheumatoid arthritis	CD86	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD86	0.31886461	0	4	5	FALSE	CD86	CD86	138	0	3	0	0.64397878	FALSE	1	CD86	744	0.5
792653	taxon:9606	3.52434221	0	181638	1902	cytochrome P450 family 1 subfamily A member 2	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0032787-&&-monocarboxylic acid metabolic process-%%-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0009403-&&-toxin biosynthetic process-%%-GO:0010468-&&-regulation of gene expression-%%-GO:0032355-&&-response to estradiol-%%-GO:0042737-&&-drug catabolic process-%%-GO:0070989-&&-oxidative demethylation-%%-GO:0009791-&&-post-embryonic development-%%-GO:0050665-&&-hydrogen peroxide biosynthetic process-%%-GO:0097267-&&-omega-hydroxylase P450 pathway-%%-GO:0006778-&&-porphyrin-containing compound metabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0030324-&&-lung development-%%-GO:0006706-&&-steroid catabolic process-%%-GO:0009820-&&-alkaloid metabolic process-%%-GO:0071280-&&-cellular response to copper ion-%%-GO:0032259-&&-methylation-%%-GO:0045333-&&-cellular respiration-%%-GO:0042738-&&-exogenous drug catabolic process-%%-GO:0071615-&&-oxidative deethylation-%%-GO:0018894-&&-dibenzo-p-dioxin metabolic process-%%-GO:0035902-&&-response to immobilization stress-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0016491-&&-oxidoreductase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0070330-&&-aromatase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0016712-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-%%-GO:0032451-&&-demethylase activity-%%-GO:0034875-&&-caffeine oxidase activity-%%-GO:0020037-&&-heme binding-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding	G:9606:CYP1A2	CYP1A2	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa00232-&&-Caffeine metabolism-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CYP1A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP1A2	0.28374089	1	4	5	FALSE	CYP1A2	CYP1A2	26	0	3	0	0.5792763	FALSE	1	CYP1A2	0	0.59090909
792690	taxon:9606	2.94753427	9.20E-07	181559	1902	dopa decarboxylase	gene	biological_process-&-1&-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0035690-&&-cellular response to drug-%%-GO:0042423-&&-catecholamine biosynthetic process-%%-GO:0046219-&&-indolalkylamine biosynthetic process-%%-GO:0071312-&&-cellular response to alkaloid-%%-GO:0010259-&&-multicellular organism aging-%%-GO:0033076-&&-isoquinoline alkaloid metabolic process-%%-GO:0042416-&&-dopamine biosynthetic process-%%-GO:0046684-&&-response to pyrethroid-%%-GO:0042427-&&-serotonin biosynthetic process-%%-GO:0006520-&&-cellular amino acid metabolic process-%%-GO:0007623-&&-circadian rhythm-%%-GO:0052314-&&-phytoalexin metabolic process-%%-GO:0015842-&&-aminergic neurotransmitter loading into synaptic vesicle|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0030424-&&-axon-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005829-&&-cytosol-%%-GO:0008021-&&-synaptic vesicle|molecular_function-&-1&-GO:0004058-&&-aromatic-L-amino-acid decarboxylase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0005515-&&-protein binding-%%-GO:0030170-&&-pyridoxal phosphate binding-%%-GO:0016597-&&-amino acid binding-%%-GO:0019904-&&-protein domain specific binding-%%-GO:0036468-&&-L-dopa decarboxylase activity	G:9606:DDC			KEGG-&-1&-hsa04728-&&-Dopaminergic synapse-%%-hsa00350-&&-Tyrosine metabolism-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00360-&&-Phenylalanine metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04726-&&-Serotonergic synapse-%%-hsa05034-&&-Alcoholism-%%-hsa05030-&&-Cocaine addiction-%%-hsa05031-&&-Amphetamine addiction	DDC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDC	0.33926662	0.16666667	4	5	FALSE	DDC	DDC	188	0	4	0	0.67541096	FALSE	0	DDC	1374	0.28195489
792749	taxon:9606	3.30219001	2.41E-06	181446	1902	ficolin 2	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0008228-&&-opsonization-%%-GO:0006956-&&-complement activation-%%-GO:0006508-&&-proteolysis-%%-GO:0001867-&&-complement activation, lectin pathway-%%-GO:0043654-&&-recognition of apoptotic cell-%%-GO:0050830-&&-defense response to Gram-positive bacterium|cellular_component-&-1&-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0003823-&&-antigen binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0048306-&&-calcium-dependent protein binding-%%-GO:2001065-&&-mannan binding-%%-GO:0043394-&&-proteoglycan binding-%%-GO:0005515-&&-protein binding	G:9606:FCN2				FCN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCN2	0.30282933	0	4	5	FALSE	FCN2	FCN2	29.75	0	4	0	0.61630166	FALSE	0	FCN2	1380	0.25669643
792769	taxon:9606	2.80841342	1.04E-06	165017	1902	transcription elongation factor A N-terminal and central domain containing 2	gene	biological_process-&-1&-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:TCEANC2				TCEANC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEANC2	0.35607293	0.16666667	4	5	FALSE	TCEANC2	TCEANC2	379.5	0	4	0	0.69859776	FALSE	0	TCEANC2	2936	0.27148997
792774	taxon:9606	3.08996376	1.58E-06	181395	1902	dermatopontin	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0031012-&&-extracellular matrix-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome	G:9606:DPT				DPT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DPT	0.32362839	0.16666667	4	5	FALSE	DPT	DPT	90.25	0	4	0	0.65167271	FALSE	0	DPT	1834	0.2624269
792850	taxon:9606	2.87600441	1.00E-06	181268	1902	epiregulin	gene	biological_process-&-1&-GO:0001550-&&-ovarian cumulus expansion-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0009887-&&-animal organ morphogenesis-%%-GO:0009299-&&-mRNA transcription-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007143-&&-female meiotic division-%%-GO:0042700-&&-luteinizing hormone signaling pathway-%%-GO:0043616-&&-keratinocyte proliferation-%%-GO:0051781-&&-positive regulation of cell division-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0001556-&&-oocyte maturation-%%-GO:0045840-&&-positive regulation of mitotic nuclear division-%%-GO:0042108-&&-positive regulation of cytokine biosynthetic process-%%-GO:0045089-&&-positive regulation of innate immune response-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0030728-&&-ovulation-%%-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0051151-&&-negative regulation of smooth muscle cell differentiation-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0045740-&&-positive regulation of DNA replication-%%-GO:0048160-&&-primary follicle stage-%%-GO:0030216-&&-keratinocyte differentiation-%%-GO:0045741-&&-positive regulation of epidermal growth factor-activated receptor activity-%%-GO:0000165-&&-MAPK cascade-%%-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0001525-&&-angiogenesis-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0001819-&&-positive regulation of cytokine production-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0042327-&&-positive regulation of phosphorylation-%%-GO:0045410-&&-positive regulation of interleukin-6 biosynthetic process-%%-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:0048146-&&-positive regulation of fibroblast proliferation-%%-GO:0042060-&&-wound healing-%%-GO:0009653-&&-anatomical structure morphogenesis|cellular_component-&-1&-GO:0005622-&&-intracellular-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0005515-&&-protein binding-%%-GO:0005154-&&-epidermal growth factor receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:EREG			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04012-&&-ErbB signaling pathway-%%-hsa04010-&&-MAPK signaling pathway-%%-hsa05210-&&-Colorectal cancer	EREG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EREG	0.34770461	0.33333333	4	4	FALSE	EREG	EREG	272.5	0	4	0	0.6873326	FALSE	0	EREG	1466	0.26457726
792934	taxon:9606	2.8342524	3.75E-06	164735	1902	regulating synaptic membrane exocytosis 4	gene	biological_process-&-1&-GO:2000300-&&-regulation of synaptic vesicle exocytosis-%%-GO:0048791-&&-calcium ion-regulated exocytosis of neurotransmitter-%%-GO:0042391-&&-regulation of membrane potential|cellular_component-&-1&-GO:0097060-&&-synaptic membrane-%%-GO:0030054-&&-cell junction-%%-GO:0048786-&&-presynaptic active zone|molecular_function-&-1&-GO:0044325-&&-ion channel binding	G:9606:RIMS4				RIMS4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RIMS4	0.35282673	0.16666667	4	5	FALSE	RIMS4	RIMS4	329.5	0	4	0	0.69429127	FALSE	0	RIMS4	9266	0.26661264
793078	taxon:9606	3.09248464	1.47E-06	164415	1902	NIMA related kinase 7	gene	biological_process-&-1&-GO:0000910-&&-cytokinesis-%%-GO:0051225-&&-spindle assembly-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:1904355-&&-positive regulation of telomere capping-%%-GO:0032212-&&-positive regulation of telomere maintenance via telomerase-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0000922-&&-spindle pole-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:NEK7			KEGG-&-1&-hsa04621-&&-NOD-like receptor signaling pathway	NEK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK7	0.32336458	0.33333333	4	5	FALSE	NEK7	NEK7	82.5	0	4	0	0.65125256	FALSE	0	NEK7	1210	0.25946372
793105	taxon:9606	3.0115015	1.35E-06	180721	1902	GTP cyclohydrolase I feedback regulator	gene	biological_process-&-1&-GO:0051291-&&-protein heterooligomerization-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0043105-&&-negative regulation of GTP cyclohydrolase I activity-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0009890-&&-negative regulation of biosynthetic process-%%-GO:0042133-&&-neurotransmitter metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0031965-&&-nuclear membrane-%%-GO:0042470-&&-melanosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0043234-&&-protein complex-%%-GO:0005634-&&-nucleus-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0030742-&&-GTP-dependent protein binding-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0005515-&&-protein binding-%%-GO:0016597-&&-amino acid binding-%%-GO:0044549-&&-GTP cyclohydrolase binding	G:9606:GCHFR				GCHFR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCHFR	0.33206027	0	4	4	FALSE	GCHFR	GCHFR	307.5	0	3	0	0.66474975	FALSE	1	GCHFR	810	0.5
793111	taxon:9606	2.90593981	2.30E-07	180719	1902	glucokinase regulator	gene	biological_process-&-1&-GO:0033132-&&-negative regulation of glucokinase activity-%%-GO:0046415-&&-urate metabolic process-%%-GO:0000060-&&-protein import into nucleus, translocation-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:1901135-&&-carbohydrate derivative metabolic process-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0010827-&&-regulation of glucose transport-%%-GO:0009750-&&-response to fructose|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070095-&&-fructose-6-phosphate binding-%%-GO:0005515-&&-protein binding	G:9606:GCKR				GCKR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GCKR	0.34412275	0.5	4	5	FALSE	GCKR	GCKR	250.75	0	4	0	0.68234336	FALSE	0	GCKR	496	0.28559226
793182	taxon:9606	3.03025051	1.40E-07	180569	1902	homeobox D8	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0008595-&&-anterior/posterior axis specification, embryo-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048705-&&-skeletal system morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001228-&&-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:HOXD8				HOXD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXD8	0.33000572	0	4	5	FALSE	HOXD8	HOXD8	150.25	0	4	0	0.66162491	FALSE	0	HOXD8	536	0.31891026
793184	taxon:9606	2.91633843	3.32E-06	180568	1902	homeobox D9	gene	biological_process-&-1&-GO:0008344-&&-adult locomotory behavior-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0035137-&&-hindlimb morphogenesis-%%-GO:0030879-&&-mammary gland development-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0048704-&&-embryonic skeletal system morphogenesis-%%-GO:0007338-&&-single fertilization-%%-GO:0009952-&&-anterior/posterior pattern specification-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005730-&&-nucleolus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	G:9606:HOXD9				HOXD9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HOXD9	0.34289573	0	4	5	FALSE	HOXD9	HOXD9	220.25	0	4	0	0.68061026	FALSE	0	HOXD9	3242	0.26039192
793186	taxon:9606	2.9418623	3.70E-07	180561	1902	4-hydroxyphenylpyruvate dioxygenase	gene	biological_process-&-1&-GO:0006559-&&-L-phenylalanine catabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006572-&&-tyrosine catabolic process|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0003868-&&-4-hydroxyphenylpyruvate dioxygenase activity-%%-GO:0046872-&&-metal ion binding	G:9606:HPD			KEGG-&-1&-hsa00350-&&-Tyrosine metabolism-%%-hsa00360-&&-Phenylalanine metabolism-%%-hsa00130-&&-Ubiquinone and other terpenoid-quinone biosynthesis-%%-hsa01100-&&-Metabolic pathways	HPD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPD	0.33992074	0.16666667	4	4	FALSE	HPD	HPD	189	0	4	0	0.67635628	FALSE	0	HPD	758	0.27083333
793196	taxon:9606	3.04506066	9.40E-07	180544	1902	ES cell expressed Ras	gene	biological_process-&-1&-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005525-&&-GTP binding	G:9606:ERAS				ERAS	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERAS	0.32840068	0.33333333	4	5	FALSE	ERAS	ERAS	114	0	4	0	0.65915656	FALSE	0	ERAS	1138	0.27948403
793199	taxon:9606	3.3415787	6.10E-07	180541	1902	histamine receptor H1	gene	biological_process-&-1&-GO:0048016-&&-inositol phosphate-mediated signaling-%%-GO:0032962-&&-positive regulation of inositol trisphosphate biosynthetic process-%%-GO:0050804-&&-modulation of synaptic transmission-%%-GO:0008542-&&-visual learning-%%-GO:0048167-&&-regulation of synaptic plasticity-%%-GO:0071420-&&-cellular response to histamine-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:0006954-&&-inflammatory response-%%-GO:0043114-&&-regulation of vascular permeability-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0048245-&&-eosinophil chemotaxis-%%-GO:0019229-&&-regulation of vasoconstriction-%%-GO:0007613-&&-memory|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004969-&&-histamine receptor activity-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:HRH1			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa04750-&&-Inflammatory mediator regulation of TRP channels	HRH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HRH1	0.29925975	0.66666667	4	5	FALSE	HRH1	HRH1	40.25	0	4	0	0.60973688	FALSE	0	HRH1	620	0.33823529
793229	taxon:9606	3.04506066	1.03E-06	164109	1902	GLI pathogenesis related 2	gene	biological_process-&-1&-GO:0070374-&&-positive regulation of ERK1 and ERK2 cascade-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:0010718-&&-positive regulation of epithelial to mesenchymal transition|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0042803-&&-protein homodimerization activity	G:9606:GLIPR2				GLIPR2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLIPR2	0.32840068	0	4	5	FALSE	GLIPR2	GLIPR2	110	0	4	0	0.65915656	FALSE	0	GLIPR2	1712	0.26520681
793230	taxon:9606	2.72018276	1.84E-06	180495	1902	DnaJ heat shock protein family (Hsp40) member C4	gene	biological_process-&-1&-GO:0006457-&&-protein folding-%%-GO:0006986-&&-response to unfolded protein|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0051082-&&-unfolded protein binding-%%-GO:0005515-&&-protein binding	G:9606:DNAJC4				DNAJC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAJC4	0.36762236	0.33333333	4	5	FALSE	DNAJC4	DNAJC4	544.75	0	4	0	0.71330287	FALSE	0	DNAJC4	3690	0.2877907
793241	taxon:9606	2.7910824	3.70E-07	180469	1902	tenascin C	gene	biological_process-&-1&-GO:0007528-&&-neuromuscular junction development-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0071774-&&-response to fibroblast growth factor-%%-GO:0060739-&&-mesenchymal-epithelial cell signaling involved in prostate gland development-%%-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0001649-&&-osteoblast differentiation-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0042475-&&-odontogenesis of dentin-containing tooth-%%-GO:0060740-&&-prostate gland epithelium morphogenesis-%%-GO:0009611-&&-response to wounding-%%-GO:0060447-&&-bud outgrowth involved in lung branching-%%-GO:0071799-&&-cellular response to prostaglandin D stimulus-%%-GO:0071305-&&-cellular response to vitamin D-%%-GO:0045471-&&-response to ethanol-%%-GO:0009612-&&-response to mechanical stimulus-%%-GO:0014012-&&-peripheral nervous system axon regeneration-%%-GO:0007155-&&-cell adhesion-%%-GO:0042060-&&-wound healing|cellular_component-&-1&-GO:0005604-&&-basement membrane-%%-GO:0031012-&&-extracellular matrix-%%-GO:0016020-&&-membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005925-&&-focal adhesion-%%-GO:0005615-&&-extracellular space-%%-GO:0005614-&&-interstitial matrix|molecular_function-&-1&-GO:0045545-&&-syndecan binding	G:9606:TNC	TNC	TRUE	KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05165-&&-Human papillomavirus infection	TNC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TNC	0.35828394	0.66666667	4	5	FALSE	TNC	TNC	422.25	0	4	0	0.70148627	FALSE	0	TNC	398	0.27926587
793314	taxon:9606	3.25649913	5.80E-07	180325	1902	complement factor H related 1	gene	biological_process-&-1&-GO:0006956-&&-complement activation|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0072562-&&-blood microparticle	G:9606:CFHR1				CFHR1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CFHR1	0.30707823	0.33333333	4	5	FALSE	CFHR1	CFHR1	31.75	0	4	0	0.62391681	FALSE	0	CFHR1	368	0.26470588
787034	taxon:9606	2.85867339	1.13E-05	163805	1902	stomatin like 3	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0008150-&&-biological_process-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005575-&&-cellular_component-%%-GO:0005886-&&-plasma membrane-%%-GO:0005929-&&-cilium|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:STOML3				STOML3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STOML3	0.34981261	0.33333333	3	5	FALSE	STOML3	STOML3	402.3333333	0	3	0	0.6902211	FALSE	0	STOML3	6460	0.34536082
787056	taxon:9606	3.08507957	1.30E-07	180155	1902	interferon alpha inducible protein 27	gene	biological_process-&-1&-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0060337-&&-type I interferon signaling pathway-%%-GO:0046825-&&-regulation of protein export from nucleus-%%-GO:0097190-&&-apoptotic signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005637-&&-nuclear inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005741-&&-mitochondrial outer membrane|molecular_function-&-1&-GO:0001102-&&-RNA polymerase II activating transcription factor binding-%%-GO:0003674-&&-molecular_function-%%-GO:0005521-&&-lamin binding	G:9606:IFI27	IFI27	TRUE		IFI27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IFI27	0.32414075	0.33333333	3	5	FALSE	IFI27	IFI27	97.33333333	0	3	0	0.65248674	FALSE	0	IFI27	216	0.37164751
787115	taxon:9606	3.9387112	3.00E-07	180033	1902	interleukin 10 receptor subunit beta	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006954-&&-inflammatory response-%%-GO:0006955-&&-immune response-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0032002-&&-interleukin-28 receptor complex|molecular_function-&-1&-GO:0004920-&&-interleukin-10 receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0004872-&&-receptor activity	G:9606:IL10RB			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05152-&&-Tuberculosis-%%-hsa05145-&&-Toxoplasmosis-%%-hsa05163-&&-Human cytomegalovirus infection-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL10RB	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL10RB	0.25389016	0.33333333	3	6	FALSE	IL10RB	IL10RB	3	0	3	0	0.5102148	FALSE	0	IL10RB	214	0.44444444
787146	taxon:9606	2.98771073	3.00E-08	163601	1902	phosphatidylethanolamine binding protein 4	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:PEBP4				PEBP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEBP4	0.33470442	0.66666667	3	5	FALSE	PEBP4	PEBP4	201	0	3	0	0.66871488	FALSE	0	PEBP4	134	0.39105058
787236	taxon:9606	2.93997164	7.74E-06	179822	1902	insulin receptor related receptor	gene	biological_process-&-1&-GO:0018108-&&-peptidyl-tyrosine phosphorylation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0031532-&&-actin cytoskeleton reorganization-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0071469-&&-cellular response to alkaline pH-%%-GO:0030238-&&-male sex determination|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0004714-&&-transmembrane receptor protein tyrosine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0043560-&&-insulin receptor substrate binding-%%-GO:0043548-&&-phosphatidylinositol 3-kinase binding	G:9606:INSRR			KEGG-&-1&-hsa05215-&&-Prostate cancer-%%-hsa04810-&&-Regulation of actin cytoskeleton	INSRR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INSRR	0.34013934	0.33333333	3	5	FALSE	INSRR	INSRR	248	0	3	0	0.67667139	FALSE	0	INSRR	6186	0.34208103
787271	taxon:9606	2.97037971	3.00E-07	163390	1902	transmembrane protease, serine 6	gene	biological_process-&-1&-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0022617-&&-extracellular matrix disassembly-%%-GO:0006879-&&-cellular iron ion homeostasis-%%-GO:0097264-&&-self proteolysis-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0055072-&&-iron ion homeostasis-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006508-&&-proteolysis-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0042730-&&-fibrinolysis-%%-GO:0033619-&&-membrane protein proteolysis-%%-GO:0001525-&&-angiogenesis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005615-&&-extracellular space-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:TMPRSS6				TMPRSS6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMPRSS6	0.3366573	0.33333333	3	5	FALSE	TMPRSS6	TMPRSS6	256	0	3	0	0.67160338	FALSE	0	TMPRSS6	608	0.3492714
787283	taxon:9606	2.92783992	9.60E-07	163362	1902	doublecortin like kinase 2	gene	biological_process-&-1&-GO:0021766-&&-hippocampus development-%%-GO:0030182-&&-neuron differentiation-%%-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0021860-&&-pyramidal neuron development-%%-GO:0000226-&&-microtubule cytoskeleton organization-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:1900181-&&-negative regulation of protein localization to nucleus-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:DCLK2				DCLK2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DCLK2	0.34154873	0	3	5	FALSE	DCLK2	DCLK2	274	0	3	0	0.67869335	FALSE	0	DCLK2	1458	0.34382872
787467	taxon:9606	3.12399559	3.00E-07	179380	1902	secretoglobin family 2A member 2	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005515-&&-protein binding	G:9606:SCGB2A2				SCGB2A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SCGB2A2	0.32010288	0	3	5	FALSE	SCGB2A2	SCGB2A2	91	0	3	0	0.64600074	FALSE	0	SCGB2A2	394	0.34351145
787472	taxon:9606	2.9470616	2.80E-07	162977	1902	kelch like family member 34	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0031463-&&-Cul3-RING ubiquitin ligase complex-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:KLHL34				KLHL34	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL34	0.33932104	0	3	4	FALSE	KLHL34	KLHL34	273.3333333	0	3	0	0.67548973	FALSE	0	KLHL34	954	0.37305936
787506	taxon:9606	3.22624862	2.29E-06	179323	1902	matrix metallopeptidase 17	gene	biological_process-&-1&-GO:0001822-&&-kidney development-%%-GO:0006508-&&-proteolysis-%%-GO:0042756-&&-drinking behavior-%%-GO:0043085-&&-positive regulation of catalytic activity|cellular_component-&-1&-GO:0031225-&&-anchored component of membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0008047-&&-enzyme activator activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:MMP17			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	MMP17	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP17	0.30995751	0	3	5	FALSE	MMP17	MMP17	72	0	3	0	0.62895856	FALSE	0	MMP17	1940	0.34299517
787551	taxon:9606	2.86324248	9.00E-07	179201	1902	metallothionein 1A	gene	biological_process-&-1&-GO:0045926-&&-negative regulation of growth-%%-GO:0071276-&&-cellular response to cadmium ion-%%-GO:0010038-&&-response to metal ion-%%-GO:0071294-&&-cellular response to zinc ion|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0048471-&&-perinuclear region of cytoplasm|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008270-&&-zinc ion binding	G:9606:MT1A			KEGG-&-1&-hsa04978-&&-Mineral absorption	MT1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MT1A	0.34925439	0.33333333	3	5	FALSE	MT1A	MT1A	412	0	3	0	0.68945959	FALSE	0	MT1A	1846	0.36047869
787555	taxon:9606	3.11154876	9.60E-07	162807	1902	integrator complex subunit 6 like	gene		G:9606:INTS6L				INTS6L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INTS6L	0.32138336	0	3	5	FALSE	INTS6L	INTS6L	103.6666667	0	3	0	0.64807521	FALSE	0	INTS6L	698	0.33661202
787579	taxon:9606	2.9766819	1.60E-07	162766	1902	mitochondrial translational initiation factor 3	gene	biological_process-&-1&-GO:0032790-&&-ribosome disassembly-%%-GO:0070124-&&-mitochondrial translational initiation|cellular_component-&-1&-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003743-&&-translation initiation factor activity-%%-GO:0043024-&&-ribosomal small subunit binding-%%-GO:0005515-&&-protein binding-%%-GO:0008135-&&-translation factor activity, RNA binding	G:9606:MTIF3				MTIF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MTIF3	0.33594453	0	3	5	FALSE	MTIF3	MTIF3	215	0	3	0	0.67055302	FALSE	0	MTIF3	640	0.3572621
787647	taxon:9606	3.10162281	2.60E-07	162633	1902	early B-cell factor 3	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding	G:9606:EBF3				EBF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EBF3	0.32241187	0	3	5	FALSE	EBF3	EBF3	121	0	3	0	0.64972953	FALSE	0	EBF3	352	0.34782609
787743	taxon:9606	3.13691508	8.00E-08	178848	1902	paraoxonase 1	gene	biological_process-&-1&-GO:0046434-&&-organophosphate catabolic process-%%-GO:0070542-&&-response to fatty acid-%%-GO:0034445-&&-negative regulation of plasma lipoprotein particle oxidation-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:0016311-&&-dephosphorylation-%%-GO:1902617-&&-response to fluoride-%%-GO:0031667-&&-response to nutrient levels-%%-GO:0051099-&&-positive regulation of binding-%%-GO:0046395-&&-carboxylic acid catabolic process-%%-GO:0009605-&&-response to external stimulus-%%-GO:0046470-&&-phosphatidylcholine metabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0009636-&&-response to toxic substance-%%-GO:0032411-&&-positive regulation of transporter activity-%%-GO:0019439-&&-aromatic compound catabolic process-%%-GO:0010875-&&-positive regulation of cholesterol efflux|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0034366-&&-spherical high-density lipoprotein particle-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0034364-&&-high-density lipoprotein particle|molecular_function-&-1&-GO:0004064-&&-arylesterase activity-%%-GO:0102007-&&-acyl-L-homoserine-lactone lactonohydrolase activity-%%-GO:0004063-&&-aryldialkylphosphatase activity-%%-GO:0005543-&&-phospholipid binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005509-&&-calcium ion binding	G:9606:PON1	PON1	TRUE		PON1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PON1	0.31878453	0.66666667	3	5	FALSE	PON1	PON1	83.33333333	0	3	0	0.64384749	FALSE	0	PON1	152	0.36231884
787884	taxon:9606	3.68126674	2.70E-07	178656	1902	peptide YY	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0007631-&&-feeding behavior-%%-GO:0032098-&&-regulation of appetite-%%-GO:0007586-&&-digestion-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0008283-&&-cell proliferation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0007010-&&-cytoskeleton organization-%%-GO:0042755-&&-eating behavior-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005179-&&-hormone activity-%%-GO:0005515-&&-protein binding-%%-GO:0005184-&&-neuropeptide hormone activity-%%-GO:0001664-&&-G-protein coupled receptor binding	G:9606:PYY	PYY	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	PYY	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PYY	0.27164562	0.33333333	3	5	FALSE	PYY	PYY	21	0	3	0	0.55312221	FALSE	0	PYY	178	0.43055556
787912	taxon:9606	3.14668347	1.37E-06	178624	1902	prostaglandin E receptor 1	gene	biological_process-&-1&-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004957-&&-prostaglandin E receptor activity	G:9606:PTGER1			KEGG-&-1&-hsa04020-&&-Calcium signaling pathway-%%-hsa05200-&&-Pathways in cancer-%%-hsa04080-&&-Neuroactive ligand-receptor interaction-%%-hsa05163-&&-Human cytomegalovirus infection	PTGER1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PTGER1	0.31779491	0	3	5	FALSE	PTGER1	PTGER1	120.3333333	0	3	0	0.64221942	FALSE	0	PTGER1	1338	0.34192932
787937	taxon:9606	3.11217898	2.50E-07	178550	1902	oxytocin/neurophysin I prepropeptide	gene	biological_process-&-1&-GO:0035811-&&-negative regulation of urine volume-%%-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0014823-&&-response to activity-%%-GO:0007507-&&-heart development-%%-GO:0060406-&&-positive regulation of penile erection-%%-GO:0030431-&&-sleep-%%-GO:0045472-&&-response to ether-%%-GO:0002125-&&-maternal aggressive behavior-%%-GO:0050806-&&-positive regulation of synaptic transmission-%%-GO:0001975-&&-response to amphetamine-%%-GO:0007613-&&-memory-%%-GO:0032355-&&-response to estradiol-%%-GO:0045778-&&-positive regulation of ossification-%%-GO:0045925-&&-positive regulation of female receptivity-%%-GO:0007565-&&-female pregnancy-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0051602-&&-response to electrical stimulus-%%-GO:0034695-&&-response to prostaglandin E-%%-GO:0042755-&&-eating behavior-%%-GO:0035176-&&-social behavior-%%-GO:0051591-&&-response to cAMP-%%-GO:0032570-&&-response to progesterone-%%-GO:0060455-&&-negative regulation of gastric acid secretion-%%-GO:0045776-&&-negative regulation of blood pressure-%%-GO:0060179-&&-male mating behavior-%%-GO:0010701-&&-positive regulation of norepinephrine secretion-%%-GO:0051930-&&-regulation of sensory perception of pain-%%-GO:0032094-&&-response to food-%%-GO:0042538-&&-hyperosmotic salinity response-%%-GO:0007625-&&-grooming behavior-%%-GO:0070474-&&-positive regulation of uterine smooth muscle contraction-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0042756-&&-drinking behavior-%%-GO:0007165-&&-signal transduction-%%-GO:0032308-&&-positive regulation of prostaglandin secretion-%%-GO:0042711-&&-maternal behavior-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0042713-&&-sperm ejaculation-%%-GO:0051965-&&-positive regulation of synapse assembly-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:0009744-&&-response to sucrose-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0045777-&&-positive regulation of blood pressure-%%-GO:0042220-&&-response to cocaine-%%-GO:0060450-&&-positive regulation of hindgut contraction|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0030141-&&-secretory granule-%%-GO:0043195-&&-terminal bouton-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005185-&&-neurohypophyseal hormone activity-%%-GO:0031855-&&-oxytocin receptor binding	G:9606:OXT			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	OXT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OXT	0.32131828	0	3	5	FALSE	OXT	OXT	138.3333333	0	3	0	0.64797017	FALSE	0	OXT	536	0.33660131
788000	taxon:9606	3.02000945	3.76E-06	178429	1902	ectonucleotide pyrophosphatase/phosphodiesterase 2	gene	biological_process-&-1&-GO:0034638-&&-phosphatidylcholine catabolic process-%%-GO:0050731-&&-positive regulation of peptidyl-tyrosine phosphorylation-%%-GO:0006928-&&-movement of cell or subcellular component-%%-GO:0006935-&&-chemotaxis-%%-GO:0009395-&&-phospholipid catabolic process-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0010634-&&-positive regulation of epithelial cell migration-%%-GO:2000394-&&-positive regulation of lamellipodium morphogenesis-%%-GO:0006955-&&-immune response-%%-GO:0090305-&&-nucleic acid phosphodiester bond hydrolysis-%%-GO:0045765-&&-regulation of angiogenesis-%%-GO:0030334-&&-regulation of cell migration-%%-GO:0006796-&&-phosphate-containing compound metabolic process-%%-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004528-&&-phosphodiesterase I activity-%%-GO:0016787-&&-hydrolase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005044-&&-scavenger receptor activity-%%-GO:0008134-&&-transcription factor binding-%%-GO:0030247-&&-polysaccharide binding-%%-GO:0004551-&&-nucleotide diphosphatase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0047391-&&-alkylglycerophosphoethanolamine phosphodiesterase activity-%%-GO:0004622-&&-lysophospholipase activity-%%-GO:0003676-&&-nucleic acid binding	G:9606:ENPP2			KEGG-&-1&-hsa00565-&&-Ether lipid metabolism	ENPP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ENPP2	0.33112479	0.33333333	3	5	FALSE	ENPP2	ENPP2	160.6666667	0	3	0	0.66333176	FALSE	0	ENPP2	1884	0.34259259
788015	taxon:9606	3.00945329	6.00E-08	178392	1902	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4	gene	biological_process-&-1&-GO:0006003-&&-fructose 2,6-bisphosphate metabolic process-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0006000-&&-fructose metabolic process-%%-GO:0061621-&&-canonical glycolysis-%%-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0003873-&&-6-phosphofructo-2-kinase activity-%%-GO:0004331-&&-fructose-2,6-bisphosphate 2-phosphatase activity	G:9606:PFKFB4			KEGG-&-1&-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04152-&&-AMPK signaling pathway	PFKFB4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PFKFB4	0.33228627	0.33333333	3	4	FALSE	PFKFB4	PFKFB4	208	0	3	0	0.66509112	FALSE	0	PFKFB4	238	0.38816199
788207	taxon:9606	3.1559792	4.00E-08	178076	1902	opsin 1, long wave sensitive	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0018298-&&-protein-chromophore linkage-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0007602-&&-phototransduction-%%-GO:0007165-&&-signal transduction-%%-GO:0032467-&&-positive regulation of cytokinesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0042622-&&-photoreceptor outer segment membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0001750-&&-photoreceptor outer segment|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0009881-&&-photoreceptor activity	G:9606:OPN1LW				OPN1LW	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OPN1LW	0.31685887	0.33333333	3	5	FALSE	OPN1LW	OPN1LW	87.33333333	0	3	0	0.64067013	FALSE	0	OPN1LW	94	0.36099585
788248	taxon:9606	2.94910982	0	178007	1902	regulatory factor X4	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0021696-&&-cerebellar cortex morphogenesis-%%-GO:0060271-&&-cilium assembly-%%-GO:0021516-&&-dorsal spinal cord development-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0030901-&&-midbrain development-%%-GO:0021914-&&-negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning-%%-GO:0021537-&&-telencephalon development-%%-GO:0070613-&&-regulation of protein processing|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0005515-&&-protein binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:RFX4				RFX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RFX4	0.33908537	0	3	5	FALSE	RFX4	RFX4	759	0	2	0	0.67514836	FALSE	1	RFX4	0	0
788317	taxon:9606	3.14495037	7.40E-07	161512	1902	glutamate rich 2	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ERICH2				ERICH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERICH2	0.31797004	0	3	5	FALSE	ERICH2	ERICH2	107.3333333	0	3	0	0.64250827	FALSE	0	ERICH2	1276	0.34190782
788354	taxon:9606	3.71388057	6.40E-07	177819	1902	C-X-C motif chemokine ligand 6	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0006935-&&-chemotaxis-%%-GO:0002446-&&-neutrophil mediated immunity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060326-&&-cell chemotaxis-%%-GO:0090023-&&-positive regulation of neutrophil chemotaxis-%%-GO:0006955-&&-immune response-%%-GO:0070098-&&-chemokine-mediated signaling pathway-%%-GO:0007165-&&-signal transduction-%%-GO:0006954-&&-inflammatory response-%%-GO:0042127-&&-regulation of cell proliferation-%%-GO:0042742-&&-defense response to bacterium|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0008009-&&-chemokine activity-%%-GO:0008201-&&-heparin binding-%%-GO:0045236-&&-CXCR chemokine receptor binding	G:9606:CXCL6			KEGG-&-1&-hsa04657-&&-IL-17 signaling pathway-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa05133-&&-Pertussis-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa05323-&&-Rheumatoid arthritis	CXCL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CXCL6	0.26926014	0.33333333	3	5	FALSE	CXCL6	CXCL6	22	0	3	0	0.54768657	FALSE	0	CXCL6	374	0.40880503
788383	taxon:9606	3.15156767	1.60E-07	177764	1902	SSX family member 4	gene	biological_process-&-1&-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:SSX4				SSX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSX4	0.3173024	0.33333333	3	5	FALSE	SSX4	SSX4	77.33333333	0	3	0	0.64140539	FALSE	0	SSX4	162	0.34841629
788535	taxon:9606	2.79801481	6.00E-08	177485	1902	small proline rich protein 1A	gene	biological_process-&-1&-GO:0018149-&&-peptide cross-linking-%%-GO:0008544-&&-epidermis development-%%-GO:0070268-&&-cornification-%%-GO:0030216-&&-keratinocyte differentiation|cellular_component-&-1&-GO:0001533-&&-cornified envelope-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005198-&&-structural molecule activity-%%-GO:0005515-&&-protein binding-%%-GO:0030674-&&-protein binding, bridging	G:9606:SPRR1A				SPRR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPRR1A	0.35739625	0.33333333	3	5	FALSE	SPRR1A	SPRR1A	550	0	3	0	0.70033086	FALSE	0	SPRR1A	624	0.36915156
788694	taxon:9606	2.80541988	1.02E-06	160787	1902	RAB43, member RAS oncogene family	gene	biological_process-&-1&-GO:1901998-&&-toxin transport-%%-GO:0019068-&&-virion assembly-%%-GO:0035526-&&-retrograde transport, plasma membrane to Golgi-%%-GO:0090382-&&-phagosome maturation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0007030-&&-Golgi organization|cellular_component-&-1&-GO:0005768-&&-endosome-%%-GO:0030670-&&-phagocytic vesicle membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0032588-&&-trans-Golgi network membrane-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0045335-&&-phagocytic vesicle|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding-%%-GO:0003924-&&-GTPase activity	G:9606:RAB43				RAB43	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB43	0.35645288	0.33333333	3	4	FALSE	RAB43	RAB43	507.6666667	0	3	0	0.69909669	FALSE	0	RAB43	5668	0.35702557
788750	taxon:9606	2.89790452	1.50E-07	177032	1902	zinc finger protein 74	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005654-&&-nucleoplasm-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF74				ZNF74	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF74	0.34507693	0	3	5	FALSE	ZNF74	ZNF74	355	0	3	0	0.68368258	FALSE	0	ZNF74	560	0.36951983
788774	taxon:9606	2.97620923	5.40E-07	160540	1902	RAB41, member RAS oncogene family	gene	biological_process-&-1&-GO:0006891-&&-intra-Golgi vesicle-mediated transport-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER-%%-GO:0042147-&&-retrograde transport, endosome to Golgi-%%-GO:0007264-&&-small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0005515-&&-protein binding	G:9606:RAB41				RAB41	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RAB41	0.33599788	0	3	5	FALSE	RAB41	RAB41	222.6666667	0	3	0	0.67063179	FALSE	0	RAB41	1096	0.36102063
788924	taxon:9606	3.26800063	4.60E-07	176587	1902	zinc finger protein 282	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ZNF282				ZNF282	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF282	0.30599749	0	3	5	FALSE	ZNF282	ZNF282	40	0	3	0	0.62199989	FALSE	0	ZNF282	446	0.35135135
788949	taxon:9606	3.14053884	7.20E-07	176544	1902	cartilage intermediate layer protein	gene	biological_process-&-1&-GO:0043569-&&-negative regulation of insulin-like growth factor receptor signaling pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031012-&&-extracellular matrix|molecular_function-&-1&-GO:0004551-&&-nucleotide diphosphatase activity-%%-GO:0004035-&&-alkaline phosphatase activity	G:9606:CILP				CILP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CILP	0.3184167	0	3	5	FALSE	CILP	CILP	107	0	3	0	0.64324353	FALSE	0	CILP	1034	0.36805556
789263	taxon:9606	3.09988971	5.60E-07	175882	1902	solute carrier family 4 member 4	gene	biological_process-&-1&-GO:0015698-&&-inorganic anion transport-%%-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0006810-&&-transport-%%-GO:0015701-&&-bicarbonate transport-%%-GO:0051453-&&-regulation of intracellular pH-%%-GO:0006814-&&-sodium ion transport-%%-GO:0098656-&&-anion transmembrane transport|cellular_component-&-1&-GO:0016323-&&-basolateral plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0008510-&&-sodium:bicarbonate symporter activity-%%-GO:0005452-&&-inorganic anion exchanger activity-%%-GO:0005515-&&-protein binding	G:9606:SLC4A4			KEGG-&-1&-hsa04964-&&-Proximal tubule bicarbonate reclamation-%%-hsa04976-&&-Bile secretion-%%-hsa04972-&&-Pancreatic secretion	SLC4A4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC4A4	0.32259212	0	3	5	FALSE	SLC4A4	SLC4A4	90	0	3	0	0.65001838	FALSE	0	SLC4A4	578	0.33840304
789271	taxon:9606	2.92500394	7.20E-07	159465	1902	mitogen-activated protein kinase kinase kinase 15	gene	biological_process-&-1&-GO:0000165-&&-MAPK cascade-%%-GO:0000186-&&-activation of MAPKK activity|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004709-&&-MAP kinase kinase kinase activity	G:9606:MAP3K15				MAP3K15	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MAP3K15	0.34187988	0.33333333	3	5	FALSE	MAP3K15	MAP3K15	313.3333333	0	3	0	0.67916601	FALSE	0	MAP3K15	1098	0.39027431
789310	taxon:9606	3.01402237	9.00E-08	175774	1902	interleukin 27 receptor subunit alpha	gene	biological_process-&-1&-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0002827-&&-positive regulation of T-helper 1 type immune response-%%-GO:0002829-&&-negative regulation of type 2 immune response-%%-GO:0048302-&&-regulation of isotype switching to IgG isotypes-%%-GO:0050830-&&-defense response to Gram-positive bacterium-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0070106-&&-interleukin-27-mediated signaling pathway-%%-GO:0006955-&&-immune response|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004888-&&-transmembrane signaling receptor activity-%%-GO:0045509-&&-interleukin-27 receptor activity	G:9606:IL27RA			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL27RA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL27RA	0.33178254	0.33333333	3	5	FALSE	IL27RA	IL27RA	159	0	3	0	0.6643296	FALSE	0	IL27RA	266	0.37598736
789984	taxon:9606	2.88388215	3.30E-07	157800	1902	Pim-3 proto-oncogene, serine/threonine kinase	gene	biological_process-&-1&-GO:0046777-&&-protein autophosphorylation-%%-GO:0006915-&&-apoptotic process-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0007346-&&-regulation of mitotic cell cycle-%%-GO:0007049-&&-cell cycle-%%-GO:0061179-&&-negative regulation of insulin secretion involved in cellular response to glucose stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005515-&&-protein binding	G:9606:PIM3				PIM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIM3	0.34675481	0.33333333	3	5	FALSE	PIM3	PIM3	362	0	3	0	0.68601964	FALSE	0	PIM3	980	0.36942458
789991	taxon:9606	3.05766504	1.93E-06	157795	1902	astacin like metalloendopeptidase	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0060468-&&-prevention of polyspermy-%%-GO:0007155-&&-cell adhesion-%%-GO:2000360-&&-negative regulation of binding of sperm to zona pellucida-%%-GO:0006508-&&-proteolysis-%%-GO:0010954-&&-positive regulation of protein processing|cellular_component-&-1&-GO:0030133-&&-transport vesicle-%%-GO:0060473-&&-cortical granule-%%-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070002-&&-glutamic-type peptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0008233-&&-peptidase activity-%%-GO:0004222-&&-metalloendopeptidase activity-%%-GO:0070001-&&-aspartic-type peptidase activity	G:9606:ASTL				ASTL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ASTL	0.32704694	0	3	5	FALSE	ASTL	ASTL	142.3333333	0	3	0	0.65705583	FALSE	0	ASTL	1696	0.33650794
790055	taxon:9606	2.90247361	2.60E-07	173988	1902	solute carrier family 7 member 9	gene	biological_process-&-1&-GO:0015811-&&-L-cystine transport-%%-GO:0050900-&&-leukocyte migration-%%-GO:0006865-&&-amino acid transport-%%-GO:0015804-&&-neutral amino acid transport-%%-GO:0006461-&&-protein complex assembly-%%-GO:0003333-&&-amino acid transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0031526-&&-brush border membrane-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0015297-&&-antiporter activity-%%-GO:0015184-&&-L-cystine transmembrane transporter activity-%%-GO:0042605-&&-peptide antigen binding-%%-GO:0015175-&&-neutral amino acid transmembrane transporter activity-%%-GO:0005515-&&-protein binding	G:9606:SLC7A9			KEGG-&-1&-hsa04974-&&-Protein digestion and absorption	SLC7A9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC7A9	0.34453371	0	3	5	FALSE	SLC7A9	SLC7A9	356	0	3	0	0.68292107	FALSE	0	SLC7A9	984	0.36410256
790058	taxon:9606	3.2023003	6.10E-07	173986	1902	TBC1 domain family member 8	gene	biological_process-&-1&-GO:0031338-&&-regulation of vesicle fusion-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006886-&&-intracellular protein transport-%%-GO:1902017-&&-regulation of cilium assembly-%%-GO:0090630-&&-activation of GTPase activity-%%-GO:0008015-&&-blood circulation|cellular_component-&-1&-GO:0012505-&&-endomembrane system-%%-GO:0005622-&&-intracellular-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0017137-&&-Rab GTPase binding	G:9606:TBC1D8				TBC1D8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBC1D8	0.31227552	0	3	5	FALSE	TBC1D8	TBC1D8	76	0	3	0	0.63294995	FALSE	0	TBC1D8	734	0.34090909
790103	taxon:9606	2.94075941	3.05E-06	173868	1902	deltex E3 ubiquitin ligase 4	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0032479-&&-regulation of type I interferon production|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:DTX4			KEGG-&-1&-hsa04330-&&-Notch signaling pathway	DTX4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DTX4	0.34004822	0.66666667	3	5	FALSE	DTX4	DTX4	254.3333333	0	3	0	0.6765401	FALSE	0	DTX4	2480	0.3508046
790104	taxon:9606	2.82070269	4.60E-07	173870	1902	neurobeachin like 2	gene	biological_process-&-1&-GO:0030220-&&-platelet formation-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane	G:9606:NBEAL2				NBEAL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NBEAL2	0.35452159	0.33333333	3	5	FALSE	NBEAL2	NBEAL2	495.6666667	0	3	0	0.69654955	FALSE	0	NBEAL2	1288	0.37048118
790226	taxon:9606	2.95809044	0	173586	1902	OTU deubiquitinase 3	gene	biological_process-&-1&-GO:0016579-&&-protein deubiquitination-%%-GO:0051898-&&-negative regulation of protein kinase B signaling-%%-GO:0050821-&&-protein stabilization-%%-GO:0071108-&&-protein K48-linked deubiquitination-%%-GO:0044313-&&-protein K6-linked deubiquitination-%%-GO:1990167-&&-protein K27-linked deubiquitination-%%-GO:0035871-&&-protein K11-linked deubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0004843-&&-thiol-dependent ubiquitin-specific protease activity	G:9606:OTUD3				OTUD3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OTUD3	0.33805593	0	3	4	FALSE	OTUD3	OTUD3	692	0	2	0	0.67365159	FALSE	1	OTUD3	0	0
790335	taxon:9606	2.86513313	9.00E-08	173294	1902	zinc finger protein 385A	gene	biological_process-&-1&-GO:2000765-&&-regulation of cytoplasmic translation-%%-GO:0007611-&&-learning or memory-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:1902164-&&-positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0030220-&&-platelet formation-%%-GO:0006915-&&-apoptotic process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006977-&&-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-%%-GO:0010609-&&-mRNA localization resulting in posttranscriptional regulation of gene expression-%%-GO:0007599-&&-hemostasis-%%-GO:0070889-&&-platelet alpha granule organization-%%-GO:0007626-&&-locomotory behavior-%%-GO:0035855-&&-megakaryocyte development-%%-GO:1902166-&&-negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0000790-&&-nuclear chromatin-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030425-&&-dendrite-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003723-&&-RNA binding-%%-GO:0008270-&&-zinc ion binding-%%-GO:0002039-&&-p53 binding-%%-GO:0003730-&&-mRNA 3'-UTR binding	G:9606:ZNF385A				ZNF385A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF385A	0.34902392	0.66666667	3	4	FALSE	ZNF385A	ZNF385A	399	0	3	0	0.68914448	FALSE	0	ZNF385A	510	0.36206897
790363	taxon:9606	2.89538365	8.36E-06	173212	1902	phosphoinositide-3-kinase regulatory subunit 5	gene	biological_process-&-1&-GO:0051897-&&-positive regulation of protein kinase B signaling-%%-GO:0030168-&&-platelet activation-%%-GO:0006661-&&-phosphatidylinositol biosynthetic process-%%-GO:0043551-&&-regulation of phosphatidylinositol 3-kinase activity-%%-GO:0014065-&&-phosphatidylinositol 3-kinase signaling-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0046854-&&-phosphatidylinositol phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005942-&&-phosphatidylinositol 3-kinase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0005815-&&-microtubule organizing center-%%-GO:0005944-&&-phosphatidylinositol 3-kinase complex, class IB-%%-GO:0005737-&&-cytoplasm-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0046935-&&-1-phosphatidylinositol-3-kinase regulator activity-%%-GO:0031683-&&-G-protein beta/gamma-subunit complex binding	G:9606:PIK3R5			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04725-&&-Cholinergic synapse-%%-hsa04062-&&-Chemokine signaling pathway-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04611-&&-Platelet activation-%%-hsa04921-&&-Oxytocin signaling pathway-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa05145-&&-Toxoplasmosis-%%-hsa04261-&&-Adrenergic signaling in cardiomyocytes-%%-hsa04022-&&-cGMP-PKG signaling pathway	PIK3R5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PIK3R5	0.34537737	0	3	5	FALSE	PIK3R5	PIK3R5	348.6666667	0	3	0	0.68410273	FALSE	0	PIK3R5	6136	0.33590982
790403	taxon:9606	3.15156767	1.60E-07	156727	1902	SSX family member 4B	gene	biological_process-&-1&-GO:1903507-&&-negative regulation of nucleic acid-templated transcription-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0003714-&&-transcription corepressor activity	G:9606:SSX4B				SSX4B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SSX4B	0.3173024	0.33333333	3	5	FALSE	SSX4B	SSX4B	77.33333333	0	3	0	0.64140539	FALSE	0	SSX4B	162	0.34841629
790436	taxon:9606	3.14069639	2.43E-06	172992	1902	gremlin 1, DAN family BMP antagonist	gene	biological_process-&-1&-GO:0072331-&&-signal transduction by p53 class mediator-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0051092-&&-positive regulation of NF-kappaB transcription factor activity-%%-GO:0006915-&&-apoptotic process-%%-GO:0030514-&&-negative regulation of BMP signaling pathway-%%-GO:0032872-&&-regulation of stress-activated MAPK cascade-%%-GO:0090027-&&-negative regulation of monocyte chemotaxis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0090291-&&-negative regulation of osteoclast proliferation-%%-GO:0003337-&&-mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0030308-&&-negative regulation of cell growth-%%-GO:0000902-&&-cell morphogenesis-%%-GO:1900086-&&-positive regulation of peptidyl-tyrosine autophosphorylation-%%-GO:1900155-&&-negative regulation of bone trabecula formation-%%-GO:0060173-&&-limb development-%%-GO:0030502-&&-negative regulation of bone mineralization-%%-GO:0051973-&&-positive regulation of telomerase activity-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:2000727-&&-positive regulation of cardiac muscle cell differentiation-%%-GO:0002042-&&-cell migration involved in sprouting angiogenesis-%%-GO:0003257-&&-positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation-%%-GO:0033689-&&-negative regulation of osteoblast proliferation-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0090090-&&-negative regulation of canonical Wnt signaling pathway-%%-GO:0060676-&&-ureteric bud formation-%%-GO:2000273-&&-positive regulation of receptor activity-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0007165-&&-signal transduction-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0046851-&&-negative regulation of bone remodeling-%%-GO:0060394-&&-negative regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:1900158-&&-negative regulation of bone mineralization involved in bone maturation-%%-GO:0010717-&&-regulation of epithelial to mesenchymal transition-%%-GO:0002092-&&-positive regulation of receptor internalization-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0042346-&&-positive regulation of NF-kappaB import into nucleus-%%-GO:0090190-&&-positive regulation of branching involved in ureteric bud morphogenesis-%%-GO:0090191-&&-negative regulation of branching involved in ureteric bud morphogenesis-%%-GO:0007171-&&-activation of transmembrane receptor protein tyrosine kinase activity-%%-GO:0032331-&&-negative regulation of chondrocyte differentiation-%%-GO:0048263-&&-determination of dorsal identity-%%-GO:0051893-&&-regulation of focal adhesion assembly-%%-GO:0043066-&&-negative regulation of apoptotic process|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0030297-&&-transmembrane receptor protein tyrosine kinase activator activity-%%-GO:0005515-&&-protein binding-%%-GO:0005125-&&-cytokine activity-%%-GO:0043184-&&-vascular endothelial growth factor receptor 2 binding-%%-GO:0036122-&&-BMP binding-%%-GO:0016015-&&-morphogen activity-%%-GO:0048018-&&-receptor agonist activity	G:9606:GREM1	GREM1	TRUE		GREM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GREM1	0.31840072	0	3	5	FALSE	GREM1	GREM1	82	0	3	0	0.64321727	FALSE	0	GREM1	1960	0.33891213
790444	taxon:9606	2.89758941	0	156529	1902	nuclear pore complex interacting protein family, member B13	gene		G:9606:NPIPB13				NPIPB13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPIPB13	0.34511446	1	3	4	FALSE	NPIPB13	NPIPB13	395	0	3	0	0.6837351	FALSE	0	NPIPB13	0	0.38763494
790487	taxon:9606	2.93571766	2.60E-07	172717	1902	kinesin family member 26A	gene	biological_process-&-1&-GO:0048484-&&-enteric nervous system development-%%-GO:0001560-&&-regulation of cell growth by extracellular stimulus-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0019886-&&-antigen processing and presentation of exogenous peptide antigen via MHC class II-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0006890-&&-retrograde vesicle-mediated transport, Golgi to ER|cellular_component-&-1&-GO:0005871-&&-kinesin complex-%%-GO:0005829-&&-cytosol-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0003777-&&-microtubule motor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity-%%-GO:0008017-&&-microtubule binding	G:9606:KIF26A				KIF26A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF26A	0.34063221	0.33333333	3	4	FALSE	KIF26A	KIF26A	279.3333333	0	3	0	0.67738039	FALSE	0	KIF26A	692	0.37051793
790502	taxon:9606	2.93745076	1.80E-07	172665	1902	calcium binding tyrosine phosphorylation regulated	gene	biological_process-&-1&-GO:0048240-&&-sperm capacitation-%%-GO:0003351-&&-epithelial cilium movement|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0097229-&&-sperm end piece-%%-GO:0035686-&&-sperm fibrous sheath-%%-GO:0005737-&&-cytoplasm-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0031514-&&-motile cilium-%%-GO:0097228-&&-sperm principal piece|molecular_function-&-1&-GO:0017124-&&-SH3 domain binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0005509-&&-calcium ion binding	G:9606:CABYR				CABYR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CABYR	0.34043124	0	3	5	FALSE	CABYR	CABYR	317.3333333	0	3	0	0.67709154	FALSE	0	CABYR	730	0.37303459
790506	taxon:9606	2.82401134	5.00E-08	172656	1902	F-box protein 10	gene	biological_process-&-1&-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0006915-&&-apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0000209-&&-protein polyubiquitination-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0000151-&&-ubiquitin ligase complex-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0005515-&&-protein binding	G:9606:FBXO10				FBXO10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO10	0.35410623	0.66666667	3	4	FALSE	FBXO10	FBXO10	605	0	3	0	0.69599811	FALSE	0	FBXO10	480	0.45763994
790654	taxon:9606	3.30975264	1.00E-07	171632	1902	UDP glucuronosyltransferase family 1 member A1	gene	biological_process-&-1&-GO:0008210-&&-estrogen metabolic process-%%-GO:0006953-&&-acute-phase response-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0042167-&&-heme catabolic process-%%-GO:0042573-&&-retinoic acid metabolic process-%%-GO:0007586-&&-digestion-%%-GO:0052695-&&-cellular glucuronidation-%%-GO:0052696-&&-flavonoid glucuronidation-%%-GO:0031100-&&-animal organ regeneration-%%-GO:0071361-&&-cellular response to ethanol-%%-GO:0071385-&&-cellular response to glucocorticoid stimulus-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0001889-&&-liver development-%%-GO:0042594-&&-response to starvation-%%-GO:0045939-&&-negative regulation of steroid metabolic process-%%-GO:0006789-&&-bilirubin conjugation-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:0007584-&&-response to nutrient-%%-GO:0070980-&&-biphenyl catabolic process-%%-GO:0052697-&&-xenobiotic glucuronidation-%%-GO:0017144-&&-drug metabolic process-%%-GO:0042493-&&-response to drug-%%-GO:0051552-&&-flavone metabolic process|cellular_component-&-1&-GO:0070069-&&-cytochrome complex-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015020-&&-glucuronosyltransferase activity-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0005496-&&-steroid binding-%%-GO:0019899-&&-enzyme binding-%%-GO:0004857-&&-enzyme inhibitor activity-%%-GO:0001972-&&-retinoic acid binding-%%-GO:0046982-&&-protein heterodimerization activity	G:9606:UGT1A1	UGT1A1	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis	UGT1A1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UGT1A1	0.30213738	0	3	5	FALSE	UGT1A1	UGT1A1	27.66666667	0	3	0	0.61504123	FALSE	0	UGT1A1	66	0.35087719
790772	taxon:9606	3.20954782	2.00E-07	171265	1902	marginal zone B and B1 cell specific protein	gene	biological_process-&-1&-GO:0002642-&&-positive regulation of immunoglobulin biosynthetic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006915-&&-apoptotic process-%%-GO:0030888-&&-regulation of B cell proliferation-%%-GO:2001274-&&-negative regulation of glucose import in response to insulin stimulus-%%-GO:0033622-&&-integrin activation-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0034663-&&-endoplasmic reticulum chaperone complex-%%-GO:0005788-&&-endoplasmic reticulum lumen	G:9606:MZB1				MZB1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MZB1	0.31157037	0	3	5	FALSE	MZB1	MZB1	66.33333333	0	3	0	0.63174203	FALSE	0	MZB1	240	0.35701275
790779	taxon:9606	3.04222467	1.50E-06	171233	1902	complement C1r subcomponent like	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0006508-&&-proteolysis-%%-GO:0006958-&&-complement activation, classical pathway|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity	G:9606:C1RL				C1RL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1RL	0.32870682	0	3	5	FALSE	C1RL	C1RL	190	0	3	0	0.65962922	FALSE	0	C1RL	2500	0.34115523
790829	taxon:9606	3.21017804	1.21E-06	171046	1902	stathmin 3	gene	biological_process-&-1&-GO:0031122-&&-cytoplasmic microtubule organization-%%-GO:0031175-&&-neuron projection development-%%-GO:0051493-&&-regulation of cytoskeleton organization-%%-GO:0007019-&&-microtubule depolymerization-%%-GO:0035021-&&-negative regulation of Rac protein signal transduction-%%-GO:0007399-&&-nervous system development-%%-GO:0031110-&&-regulation of microtubule polymerization or depolymerization-%%-GO:0043087-&&-regulation of GTPase activity|cellular_component-&-1&-GO:0030426-&&-growth cone-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0030424-&&-axon-%%-GO:0005737-&&-cytoplasm-%%-GO:0043005-&&-neuron projection|molecular_function-&-1&-GO:0015631-&&-tubulin binding-%%-GO:0019904-&&-protein domain specific binding	G:9606:STMN3				STMN3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STMN3	0.3115092	0	3	5	FALSE	STMN3	STMN3	60.33333333	0	3	0	0.63163699	FALSE	0	STMN3	544	0.33333333
790832	taxon:9606	2.77406649	2.60E-07	171035	1902	T-box 22	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0007275-&&-multicellular organism development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0005515-&&-protein binding	G:9606:TBX22				TBX22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TBX22	0.36048163	0.66666667	3	4	FALSE	TBX22	TBX22	598.3333333	0	3	0	0.70432225	FALSE	0	TBX22	2606	0.38013554
791059	taxon:9606	2.89286277	9.00E-07	170200	1902	DExD/H-box helicase 60	gene	biological_process-&-1&-GO:0045087-&&-innate immune response-%%-GO:0009615-&&-response to virus-%%-GO:1900246-&&-positive regulation of RIG-I signaling pathway-%%-GO:1900245-&&-positive regulation of MDA-5 signaling pathway-%%-GO:0051607-&&-defense response to virus|cellular_component-&-1&-GO:0045111-&&-intermediate filament cytoskeleton-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004386-&&-helicase activity-%%-GO:0003690-&&-double-stranded DNA binding-%%-GO:0005524-&&-ATP binding-%%-GO:0003725-&&-double-stranded RNA binding-%%-GO:0003727-&&-single-stranded RNA binding-%%-GO:0005515-&&-protein binding	G:9606:DDX60				DDX60	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DDX60	0.34567834	0	3	5	FALSE	DDX60	DDX60	347.6666667	0	3	0	0.68452287	FALSE	0	DDX60	1704	0.34221783
791070	taxon:9606	2.88498503	7.00E-08	170149	1902	vacuolar protein sorting 13 homolog D	gene	cellular_component-&-1&-GO:0070062-&&-extracellular exosome	G:9606:VPS13D				VPS13D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VPS13D	0.34662225	0.33333333	3	5	FALSE	VPS13D	VPS13D	362	0	3	0	0.68583583	FALSE	0	VPS13D	226	0.36166667
791148	taxon:9606	2.95052781	4.60E-07	169884	1902	G2/M-phase specific E3 ubiquitin protein ligase	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0016567-&&-protein ubiquitination-%%-GO:0007275-&&-multicellular organism development|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding-%%-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:G2E3				G2E3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-G2E3	0.33892241	0	3	5	FALSE	G2E3	G2E3	257.6666667	0	3	0	0.67491203	FALSE	0	G2E3	828	0.35451197
791218	taxon:9606	2.89538365	1.50E-06	169701	1902	ubiquitin specific peptidase 29	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity	G:9606:USP29				USP29	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP29	0.34537737	0	3	4	FALSE	USP29	USP29	338.3333333	0	3	0	0.68410273	FALSE	0	USP29	2834	0.34005376
791251	taxon:9606	3.67937608	3.11E-06	169534	1902	matrix metallopeptidase 26	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0050728-&&-negative regulation of inflammatory response-%%-GO:0030574-&&-collagen catabolic process|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:MMP26				MMP26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP26	0.27178521	0	3	5	FALSE	MMP26	MMP26	24.66666667	0	3	0	0.55343732	FALSE	0	MMP26	1600	0.34803922
791279	taxon:9606	3.32093903	4.10E-07	169388	1902	dispatched RND transporter family member 3	gene	biological_process-&-1&-GO:0045834-&&-positive regulation of lipid metabolic process-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0032368-&&-regulation of lipid transport-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation|cellular_component-&-1&-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005737-&&-cytoplasm-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:DISP3				DISP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DISP3	0.30111965	0	3	5	FALSE	DISP3	DISP3	45.33333333	0	3	0	0.61317683	FALSE	0	DISP3	286	0.33585859
791291	taxon:9606	3.03749803	3.25E-06	169318	1902	zinc finger and AT-hook domain containing	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0060712-&&-spongiotrophoblast layer development|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:ZFAT				ZFAT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZFAT	0.32921832	0	3	5	FALSE	ZFAT	ZFAT	153.3333333	0	3	0	0.66041699	FALSE	0	ZFAT	1424	0.33627667
791370	taxon:9606	3.31117063	4.10E-07	168926	1902	protein phosphatase 4 regulatory subunit 4	gene	biological_process-&-1&-GO:0032515-&&-negative regulation of phosphoprotein phosphatase activity-%%-GO:0080163-&&-regulation of protein serine/threonine phosphatase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0008287-&&-protein serine/threonine phosphatase complex-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0019888-&&-protein phosphatase regulator activity-%%-GO:0005515-&&-protein binding	G:9606:PPP4R4				PPP4R4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PPP4R4	0.30200799	0	3	5	FALSE	PPP4R4	PPP4R4	46.66666667	0	3	0	0.61480489	FALSE	0	PPP4R4	318	0.3382716
791375	taxon:9606	2.9818812	8.00E-08	168909	1902	RB associated KRAB zinc finger	gene	biological_process-&-1&-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0008270-&&-zinc ion binding	G:9606:RBAK				RBAK	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RBAK	0.33535877	0.33333333	3	5	FALSE	RBAK	RBAK	237	0	3	0	0.66968647	FALSE	0	RBAK	250	0.38357645
791462	taxon:9606	2.99984245	3.30E-07	168541	1902	LBH domain containing 1	gene		G:9606:LBHD1				LBHD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LBHD1	0.33335084	0.33333333	3	5	FALSE	LBHD1	LBHD1	237	0	3	0	0.66669293	FALSE	0	LBHD1	492	0.37153323
791478	taxon:9606	2.94249252	7.40E-07	168464	1902	DMRT like family A1	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001541-&&-ovarian follicle development-%%-GO:0060179-&&-male mating behavior-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:DMRTA1				DMRTA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMRTA1	0.33984793	0	3	5	FALSE	DMRTA1	DMRTA1	249	0	3	0	0.67625125	FALSE	0	DMRTA1	1082	0.34396671
791489	taxon:9606	3.51126516	0	168423	1902	leucine rich repeat containing 4	gene	biological_process-&-1&-GO:0046426-&&-negative regulation of JAK-STAT cascade-%%-GO:0019221-&&-cytokine-mediated signaling pathway-%%-GO:0097119-&&-postsynaptic density protein 95 clustering-%%-GO:0006469-&&-negative regulation of protein kinase activity-%%-GO:0050807-&&-regulation of synapse organization|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030054-&&-cell junction-%%-GO:0043197-&&-dendritic spine-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0060076-&&-excitatory synapse|molecular_function-&-1&-GO:0004860-&&-protein kinase inhibitor activity-%%-GO:0005515-&&-protein binding	G:9606:LRRC4			KEGG-&-1&-hsa04360-&&-Axon guidance-%%-hsa04514-&&-Cell adhesion molecules (CAMs)	LRRC4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRC4	0.28479763	0	3	5	FALSE	LRRC4	LRRC4	90	0	2	0	0.58145581	FALSE	1	LRRC4	0	0
791501	taxon:9606	3.12651646	1.30E-06	168363	1902	rhomboid 5 homolog 1	gene	biological_process-&-1&-GO:0042058-&&-regulation of epidermal growth factor receptor signaling pathway-%%-GO:0016485-&&-protein processing-%%-GO:0015031-&&-protein transport-%%-GO:0008283-&&-cell proliferation-%%-GO:0050708-&&-regulation of protein secretion-%%-GO:0061136-&&-regulation of proteasomal protein catabolic process-%%-GO:0016477-&&-cell migration-%%-GO:0050709-&&-negative regulation of protein secretion|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0000139-&&-Golgi membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0019838-&&-growth factor binding	G:9606:RHBDF1				RHBDF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RHBDF1	0.31984479	0	3	5	FALSE	RHBDF1	RHBDF1	92	0	3	0	0.64558059	FALSE	0	RHBDF1	856	0.33579336
791504	taxon:9606	3.01087128	0	168353	1902	NFKB inhibitor zeta	gene	biological_process-&-1&-GO:0006954-&&-inflammatory response-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000932-&&-P-body-%%-GO:0016607-&&-nuclear speck-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003712-&&-transcription cofactor activity-%%-GO:0005515-&&-protein binding	G:9606:NFKBIZ			KEGG-&-1&-hsa05202-&&-Transcriptional misregulation in cancer	NFKBIZ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NFKBIZ	0.33212977	1	3	5	FALSE	NFKBIZ	NFKBIZ	195	0	3	0	0.66485479	FALSE	0	NFKBIZ	0	0.39156627
791517	taxon:9606	3.06443989	3.30E-07	168309	1902	CUB and Sushi multiple domains 1	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:CSMD1				CSMD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CSMD1	0.32632391	0	3	4	FALSE	CSMD1	CSMD1	124.6666667	0	3	0	0.65592668	FALSE	0	CSMD1	606	0.34256694
791530	taxon:9606	3.00582953	2.90E-07	168235	1902	transmembrane protease, serine 3	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006883-&&-cellular sodium ion homeostasis|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity-%%-GO:0017080-&&-sodium channel regulator activity-%%-GO:0004252-&&-serine-type endopeptidase activity	G:9606:TMPRSS3				TMPRSS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMPRSS3	0.33268686	0	3	5	FALSE	TMPRSS3	TMPRSS3	174.3333333	0	3	0	0.66569508	FALSE	0	TMPRSS3	506	0.3480589
791544	taxon:9606	2.9268946	1.00E-08	168125	1902	NADPH oxidase 5	gene	biological_process-&-1&-GO:0042554-&&-superoxide anion generation-%%-GO:0001935-&&-endothelial cell proliferation-%%-GO:0010155-&&-regulation of proton transport-%%-GO:0006915-&&-apoptotic process-%%-GO:0000910-&&-cytokinesis-%%-GO:0001525-&&-angiogenesis-%%-GO:0000302-&&-response to reactive oxygen species-%%-GO:0043012-&&-regulation of fusion of sperm to egg plasma membrane-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008283-&&-cell proliferation-%%-GO:0015992-&&-proton transport-%%-GO:0050663-&&-cytokine secretion|cellular_component-&-1&-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0016175-&&-superoxide-generating NADPH oxidase activity-%%-GO:0050661-&&-NADP binding-%%-GO:0015252-&&-hydrogen ion channel activity-%%-GO:0020037-&&-heme binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0005509-&&-calcium ion binding	G:9606:NOX5				NOX5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NOX5	0.34165904	0.33333333	3	5	FALSE	NOX5	NOX5	306.6666667	0	3	0	0.6788509	FALSE	0	NOX5	104	0.38874788
791552	taxon:9606	2.88624547	2.98E-06	168056	1902	cysteinyl-tRNA synthetase 2, mitochondrial (putative)	gene	biological_process-&-1&-GO:0006423-&&-cysteinyl-tRNA aminoacylation|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004817-&&-cysteine-tRNA ligase activity-%%-GO:0046872-&&-metal ion binding-%%-GO:0005524-&&-ATP binding	G:9606:CARS2			KEGG-&-1&-hsa00970-&&-Aminoacyl-tRNA biosynthesis	CARS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CARS2	0.34647088	0	3	5	FALSE	CARS2	CARS2	342	0	3	0	0.68562575	FALSE	0	CARS2	2350	0.34031936
791594	taxon:9606	2.86922956	1.32E-06	167899	1902	inositol-trisphosphate 3-kinase C	gene	biological_process-&-1&-GO:0043647-&&-inositol phosphate metabolic process-%%-GO:0016310-&&-phosphorylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0016607-&&-nuclear speck|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008440-&&-inositol-1,4,5-trisphosphate 3-kinase activity-%%-GO:0005516-&&-calmodulin binding	G:9606:ITPKC			KEGG-&-1&-hsa04070-&&-Phosphatidylinositol signaling system-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	ITPKC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITPKC	0.34852562	0.33333333	3	4	FALSE	ITPKC	ITPKC	402.6666667	0	3	0	0.68846174	FALSE	0	ITPKC	1460	0.36311673
791613	taxon:9606	2.79785726	1.00E-08	167813	1902	armadillo repeat containing 5	gene	cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm	G:9606:ARMC5			KEGG-&-1&-hsa04934-&&-Cushing syndrome	ARMC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARMC5	0.35741638	0.66666667	3	4	FALSE	ARMC5	ARMC5	585.3333333	0	3	0	0.70035712	FALSE	0	ARMC5	70	0.39074321
791617	taxon:9606	3.00598708	7.30E-07	167792	1902	Rho GTPase activating protein 28	gene	biological_process-&-1&-GO:1904425-&&-negative regulation of GTP binding-%%-GO:0007165-&&-signal transduction-%%-GO:0051497-&&-negative regulation of stress fiber assembly-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0051056-&&-regulation of small GTPase mediated signal transduction|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity	G:9606:ARHGAP28				ARHGAP28	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARHGAP28	0.33266943	0.33333333	3	5	FALSE	ARHGAP28	ARHGAP28	197.3333333	0	3	0	0.66566882	FALSE	0	ARHGAP28	1346	0.36014625
791621	taxon:9606	2.89758941	0	167776	1902	ATP/GTP binding protein like 2	gene	biological_process-&-1&-GO:0035610-&&-protein side chain deglutamylation-%%-GO:0006508-&&-proteolysis|cellular_component-&-1&-GO:0005814-&&-centriole-%%-GO:0036064-&&-ciliary basal body-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0004181-&&-metallocarboxypeptidase activity	G:9606:AGBL2				AGBL2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGBL2	0.34511446	1	3	4	FALSE	AGBL2	AGBL2	395	0	3	0	0.6837351	FALSE	0	AGBL2	0	0.38763494
791726	taxon:9606	2.9965338	7.70E-07	167177	1902	coiled-coil domain containing 70	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:CCDC70				CCDC70	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CCDC70	0.33371891	0	3	5	FALSE	CCDC70	CCDC70	210.6666667	0	3	0	0.66724437	FALSE	0	CCDC70	1568	0.35238095
791727	taxon:9606	3.49771546	3.50E-07	167166	1902	glycosyltransferase 8 domain containing 2	gene	biological_process-&-1&-GO:0000271-&&-polysaccharide biosynthetic process|cellular_component-&-1&-GO:0005794-&&-Golgi apparatus-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0016757-&&-transferase activity, transferring glycosyl groups	G:9606:GLT8D2				GLT8D2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLT8D2	0.2859009	0	3	5	FALSE	GLT8D2	GLT8D2	17.66666667	0	3	0	0.58371409	FALSE	0	GLT8D2	132	0.33333333
791735	taxon:9606	3.03938869	1.14E-06	167125	1902	testis expressed 101	gene	biological_process-&-1&-GO:0006501-&&-C-terminal protein lipidation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0002080-&&-acrosomal membrane-%%-GO:0005886-&&-plasma membrane	G:9606:TEX101				TEX101	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TEX101	0.32901353	0.33333333	3	4	FALSE	TEX101	TEX101	172	0	3	0	0.66010189	FALSE	0	TEX101	1400	0.33993399
791742	taxon:9606	4.12856468	0	167091	1902	inhibin beta E subunit	gene	biological_process-&-1&-GO:0010862-&&-positive regulation of pathway-restricted SMAD protein phosphorylation-%%-GO:0043408-&&-regulation of MAPK cascade-%%-GO:0060395-&&-SMAD protein signal transduction-%%-GO:0048468-&&-cell development-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005160-&&-transforming growth factor beta receptor binding-%%-GO:0008083-&&-growth factor activity-%%-GO:0005125-&&-cytokine activity-%%-GO:0005179-&&-hormone activity	G:9606:INHBE			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	INHBE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-INHBE	0.24221493	0	3	6	FALSE	INHBE	INHBE	8	0	2	0	0.47857255	FALSE	1	INHBE	0	0
791750	taxon:9606	2.97447613	1.00E-07	167071	1902	ubiquitin specific peptidase 26	gene	biological_process-&-1&-GO:0006511-&&-ubiquitin-dependent protein catabolic process-%%-GO:0016579-&&-protein deubiquitination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0036459-&&-thiol-dependent ubiquitinyl hydrolase activity-%%-GO:0005515-&&-protein binding	G:9606:USP26				USP26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-USP26	0.33619365	0	3	5	FALSE	USP26	USP26	207.3333333	0	3	0	0.67092064	FALSE	0	USP26	352	0.36135435
791752	taxon:9606	2.77579959	9.70E-07	167059	1902	radial spoke 3 homolog	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:RSPH3				RSPH3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RSPH3	0.36025656	0.33333333	3	5	FALSE	RSPH3	RSPH3	572.6666667	0	3	0	0.7040334	FALSE	0	RSPH3	6316	0.3657082
791775	taxon:9606	3.09169686	6.00E-08	166942	1902	NLR family CARD domain containing 5	gene	biological_process-&-1&-GO:0043549-&&-regulation of kinase activity-%%-GO:0060335-&&-positive regulation of interferon-gamma-mediated signaling pathway-%%-GO:0051607-&&-defense response to virus-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0060339-&&-negative regulation of type I interferon-mediated signaling pathway-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0032480-&&-negative regulation of type I interferon production-%%-GO:0045345-&&-positive regulation of MHC class I biosynthetic process-%%-GO:0045087-&&-innate immune response-%%-GO:0060340-&&-positive regulation of type I interferon-mediated signaling pathway|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding-%%-GO:0000979-&&-RNA polymerase II core promoter sequence-specific DNA binding	G:9606:NLRC5				NLRC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRC5	0.32344698	0.33333333	3	5	FALSE	NLRC5	NLRC5	117.6666667	0	3	0	0.65138386	FALSE	0	NLRC5	120	0.46560847
791795	taxon:9606	2.77706003	9.60E-07	166825	1902	acyl-CoA binding domain containing 6	gene	biological_process-&-1&-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0000062-&&-fatty-acyl-CoA binding-%%-GO:0008289-&&-lipid binding	G:9606:ACBD6				ACBD6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACBD6	0.36009304	0	3	5	FALSE	ACBD6	ACBD6	582.3333333	0	3	0	0.70382333	FALSE	0	ACBD6	6274	0.3709849
791812	taxon:9606	3.02946274	1.48E-06	166757	1902	zinc finger and BTB domain containing 37	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZBTB37				ZBTB37	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB37	0.33009153	0	3	5	FALSE	ZBTB37	ZBTB37	166.6666667	0	3	0	0.66175621	FALSE	0	ZBTB37	1160	0.34158076
791841	taxon:9606	3.24389475	3.50E-07	182991	1902	N-acetyltransferase 1	gene	biological_process-&-1&-GO:0006805-&&-xenobiotic metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004060-&&-arylamine N-acetyltransferase activity	G:9606:NAT1			KEGG-&-1&-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00232-&&-Caffeine metabolism-%%-hsa05204-&&-Chemical carcinogenesis	NAT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAT1	0.30827141	0	3	5	FALSE	NAT1	NAT1	81.66666667	0	3	0	0.62601754	FALSE	0	NAT1	526	0.34180791
791872	taxon:9606	3.20214274	5.20E-07	182949	1902	perilipin 2	gene	biological_process-&-1&-GO:0015909-&&-long-chain fatty acid transport-%%-GO:0014070-&&-response to organic cyclic compound-%%-GO:0042493-&&-response to drug-%%-GO:0019915-&&-lipid storage|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005829-&&-cytosol-%%-GO:0005811-&&-lipid particle-%%-GO:0005886-&&-plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005783-&&-endoplasmic reticulum	G:9606:PLIN2			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	PLIN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLIN2	0.31229089	0	3	5	FALSE	PLIN2	PLIN2	54.33333333	0	3	0	0.63297621	FALSE	0	PLIN2	438	0.33970276
791883	taxon:9606	2.74271309	3.90E-07	166546	1902	serine active site containing 1	gene	biological_process-&-1&-GO:0030198-&&-extracellular matrix organization-%%-GO:0008654-&&-phospholipid biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005739-&&-mitochondrion-%%-GO:0005783-&&-endoplasmic reticulum	G:9606:SERAC1				SERAC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERAC1	0.36460248	0.66666667	3	5	FALSE	SERAC1	SERAC1	660.3333333	0	3	0	0.70954782	FALSE	0	SERAC1	686	0.37160008
791936	taxon:9606	3.10209548	4.00E-07	182846	1902	arachidonate 15-lipoxygenase, type B	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0010744-&&-positive regulation of macrophage derived foam cell differentiation-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019372-&&-lipoxygenase pathway-%%-GO:0043651-&&-linoleic acid metabolic process-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0045786-&&-negative regulation of cell cycle-%%-GO:0030856-&&-regulation of epithelial cell differentiation-%%-GO:0051122-&&-hepoxilin biosynthetic process-%%-GO:0090197-&&-positive regulation of chemokine secretion-%%-GO:0035360-&&-positive regulation of peroxisome proliferator activated receptor signaling pathway-%%-GO:0030850-&&-prostate gland development-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0045926-&&-negative regulation of growth-%%-GO:0006915-&&-apoptotic process-%%-GO:0045618-&&-positive regulation of keratinocyte differentiation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0019898-&&-extrinsic component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005622-&&-intracellular-%%-GO:0005856-&&-cytoskeleton-%%-GO:0005829-&&-cytosol-%%-GO:0005634-&&-nucleus-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0050473-&&-arachidonate 15-lipoxygenase activity-%%-GO:0016165-&&-linoleate 13S-lipoxygenase activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0036403-&&-arachidonate 8(S)-lipoxygenase activity-%%-GO:0008289-&&-lipid binding	G:9606:ALOX15B			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa04726-&&-Serotonergic synapse-%%-hsa00590-&&-Arachidonic acid metabolism	ALOX15B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALOX15B	0.32236274	0.33333333	3	5	FALSE	ALOX15B	ALOX15B	101.3333333	0	3	0	0.64965075	FALSE	0	ALOX15B	414	0.40239044
791953	taxon:9606	2.74034977	3.00E-08	166425	1902	kinase non-catalytic C-lobe domain containing 1	gene	biological_process-&-1&-GO:0048814-&&-regulation of dendrite morphogenesis-%%-GO:0001934-&&-positive regulation of protein phosphorylation-%%-GO:0021707-&&-cerebellar granule cell differentiation-%%-GO:0007264-&&-small GTPase mediated signal transduction-%%-GO:0008150-&&-biological_process-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0030425-&&-dendrite-%%-GO:0032045-&&-guanyl-nucleotide exchange factor complex-%%-GO:0043025-&&-neuronal cell body|molecular_function-&-1&-GO:0003674-&&-molecular_function-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity	G:9606:KNDC1				KNDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KNDC1	0.36491692	0.33333333	3	4	FALSE	KNDC1	KNDC1	763.3333333	0	3	0	0.7099417	FALSE	0	KNDC1	464	0.41444867
792046	taxon:9606	2.92248306	5.60E-07	166304	1902	STE20-related kinase adaptor alpha	gene	biological_process-&-1&-GO:0071902-&&-positive regulation of protein serine/threonine kinase activity-%%-GO:0006611-&&-protein export from nucleus-%%-GO:0007050-&&-cell cycle arrest-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0032147-&&-activation of protein kinase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0019900-&&-kinase binding-%%-GO:0005524-&&-ATP binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0043539-&&-protein serine/threonine kinase activator activity-%%-GO:0004672-&&-protein kinase activity-%%-GO:0005515-&&-protein binding	G:9606:STRADA			KEGG-&-1&-hsa04152-&&-AMPK signaling pathway-%%-hsa04150-&&-mTOR signaling pathway	STRADA	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STRADA	0.34217478	0.33333333	3	5	FALSE	STRADA	STRADA	306.3333333	0	3	0	0.67958616	FALSE	0	STRADA	1172	0.34459459
792060	taxon:9606	3.07767449	2.00E-08	182678	1902	Kruppel like factor 9	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter-%%-GO:0010839-&&-negative regulation of keratinocyte proliferation-%%-GO:0071387-&&-cellular response to cortisol stimulus-%%-GO:0007623-&&-circadian rhythm-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0097067-&&-cellular response to thyroid hormone stimulus|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:KLF9				KLF9	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLF9	0.32492065	0.66666667	3	5	FALSE	KLF9	KLF9	155.6666667	0	3	0	0.65372092	FALSE	0	KLF9	44	0.38436214
792095	taxon:9606	2.9470616	2.80E-07	166231	1902	kelch like family member 6	gene	biological_process-&-1&-GO:0050853-&&-B cell receptor signaling pathway-%%-GO:0002467-&&-germinal center formation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0000976-&&-transcription regulatory region sequence-specific DNA binding	G:9606:KLHL6				KLHL6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KLHL6	0.33932104	0	3	4	FALSE	KLHL6	KLHL6	273.3333333	0	3	0	0.67548973	FALSE	0	KLHL6	954	0.37305936
792111	taxon:9606	3.12998267	9.10E-07	182592	1902	collagen type VI alpha 3 chain	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0030574-&&-collagen catabolic process-%%-GO:0007517-&&-muscle organ development-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0031012-&&-extracellular matrix-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005589-&&-collagen type VI trimer-%%-GO:1903561-&&-extracellular vesicle-%%-GO:0042383-&&-sarcolemma|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:COL6A3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection	COL6A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL6A3	0.31949059	0	3	5	FALSE	COL6A3	COL6A3	92	0	3	0	0.64500289	FALSE	0	COL6A3	1146	0.34082397
792115	taxon:9606	2.90263116	4.47E-06	182586	1902	collagen type IX alpha 3 chain	gene	biological_process-&-1&-GO:0008584-&&-male gonad development-%%-GO:0008585-&&-female gonad development-%%-GO:0030198-&&-extracellular matrix organization|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005788-&&-endoplasmic reticulum lumen-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005594-&&-collagen type IX trimer|molecular_function-&-1&-GO:0030020-&&-extracellular matrix structural constituent conferring tensile strength	G:9606:COL9A3			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa04512-&&-ECM-receptor interaction-%%-hsa04510-&&-Focal adhesion-%%-hsa04974-&&-Protein digestion and absorption-%%-hsa05165-&&-Human papillomavirus infection	COL9A3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COL9A3	0.34451501	0.33333333	3	5	FALSE	COL9A3	COL9A3	323.6666667	0	3	0	0.68289481	FALSE	0	COL9A3	2920	0.33540802
792334	taxon:9606	3.14999212	2.91E-06	182209	1902	aldo-keto reductase family 1 member C4	gene	biological_process-&-1&-GO:0044597-&&-daunorubicin metabolic process-%%-GO:0015721-&&-bile acid and bile salt transport-%%-GO:0008209-&&-androgen metabolic process-%%-GO:0001523-&&-retinoid metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0006699-&&-bile acid biosynthetic process-%%-GO:0044598-&&-doxorubicin metabolic process-%%-GO:0071395-&&-cellular response to jasmonic acid stimulus|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0047023-&&-androsterone dehydrogenase activity-%%-GO:0009055-&&-electron carrier activity-%%-GO:0016655-&&-oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor-%%-GO:0047743-&&-chlordecone reductase activity-%%-GO:0004033-&&-aldo-keto reductase (NADP) activity-%%-GO:0001758-&&-retinal dehydrogenase activity-%%-GO:0015125-&&-bile acid transmembrane transporter activity	G:9606:AKR1C4			KEGG-&-1&-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa00120-&&-Primary bile acid biosynthesis	AKR1C4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AKR1C4	0.31746111	0.33333333	3	5	FALSE	AKR1C4	AKR1C4	101.3333333	0	3	0	0.64166798	FALSE	0	AKR1C4	2154	0.33779264
792404	taxon:9606	2.79060974	2.80E-07	165698	1902	chromosome 10 open reading frame 90	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005813-&&-centrosome-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0051393-&&-alpha-actinin binding-%%-GO:0042826-&&-histone deacetylase binding	G:9606:C10orf90				C10orf90	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C10orf90	0.35834463	0.33333333	3	4	FALSE	C10orf90	C10orf90	576.6666667	0	3	0	0.70156504	FALSE	0	C10orf90	928	0.38654147
792496	taxon:9606	3.72522452	0	165526	1902	C1q and tumor necrosis factor related protein 5	gene	biological_process-&-1&-GO:0009306-&&-protein secretion-%%-GO:0070206-&&-protein trimerization-%%-GO:0048839-&&-inner ear development|cellular_component-&-1&-GO:0030133-&&-transport vesicle-%%-GO:0005581-&&-collagen trimer-%%-GO:0005615-&&-extracellular space-%%-GO:0042995-&&-cell projection-%%-GO:0070062-&&-extracellular exosome-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005923-&&-bicellular tight junction-%%-GO:0016328-&&-lateral plasma membrane|molecular_function-&-1&-GO:0042802-&&-identical protein binding	G:9606:C1QTNF5				C1QTNF5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QTNF5	0.2684402	0	3	5	FALSE	C1QTNF5	C1QTNF5	47	0	2	0	0.54579591	FALSE	1	C1QTNF5	0	0
792549	taxon:9606	3.43721443	9.00E-08	165443	1902	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0032091-&&-negative regulation of protein binding-%%-GO:0001501-&&-skeletal system development-%%-GO:0043392-&&-negative regulation of DNA binding-%%-GO:0007179-&&-transforming growth factor beta receptor signaling pathway-%%-GO:0060021-&&-palate development-%%-GO:0048747-&&-muscle fiber development|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity	G:9606:WFIKKN2				WFIKKN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WFIKKN2	0.29093326	0.66666667	3	5	FALSE	WFIKKN2	WFIKKN2	38.66666667	0	3	0	0.59379759	FALSE	0	WFIKKN2	64	0.37179487
792599	taxon:9606	2.98818339	0	181739	1902	dual specificity phosphatase 2	gene	biological_process-&-1&-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0001706-&&-endoderm formation-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0031965-&&-nuclear membrane|molecular_function-&-1&-GO:0051019-&&-mitogen-activated protein kinase binding-%%-GO:0008330-&&-protein tyrosine/threonine phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0005515-&&-protein binding	G:9606:DUSP2			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP2	0.33465148	1	3	5	FALSE	DUSP2	DUSP2	275	0	3	0	0.6686361	FALSE	0	DUSP2	0	0.46610169
792601	taxon:9606	3.07861982	6.00E-08	181733	1902	dual specificity phosphatase 8	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0016791-&&-phosphatase activity-%%-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity	G:9606:DUSP8			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP8	0.32482088	0.33333333	3	5	FALSE	DUSP8	DUSP8	116	0	3	0	0.65356336	FALSE	0	DUSP8	96	0.40584795
792705	taxon:9606	3.02615409	2.00E-08	165148	1902	zinc finger SWIM-type containing 7	gene	biological_process-&-1&-GO:0050821-&&-protein stabilization-%%-GO:0000724-&&-double-strand break repair via homologous recombination|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0097196-&&-Shu complex|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005515-&&-protein binding	G:9606:ZSWIM7				ZSWIM7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZSWIM7	0.33045244	0	3	5	FALSE	ZSWIM7	ZSWIM7	161	0	3	0	0.66230765	FALSE	0	ZSWIM7	138	0.38369305
792709	taxon:9606	3.03544982	7.30E-07	165138	1902	tetratricopeptide repeat domain 39C	gene		G:9606:TTC39C				TTC39C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TTC39C	0.32944047	0	3	5	FALSE	TTC39C	TTC39C	162.6666667	0	3	0	0.66075836	FALSE	0	TTC39C	660	0.3454416
792748	taxon:9606	2.98062077	2.60E-07	165063	1902	Src homology 2 domain containing E	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0009967-&&-positive regulation of signal transduction|molecular_function-&-1&-GO:0005070-&&-SH3/SH2 adaptor activity-%%-GO:0005515-&&-protein binding	G:9606:SHE				SHE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SHE	0.33550058	0.66666667	3	4	FALSE	SHE	SHE	207	0	3	0	0.66989654	FALSE	0	SHE	430	0.37163375
792785	taxon:9606	2.88419726	5.30E-07	181370	1902	multiple EGF like domains 6	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0005509-&&-calcium ion binding-%%-GO:0005515-&&-protein binding	G:9606:MEGF6				MEGF6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MEGF6	0.34671692	0.33333333	3	5	FALSE	MEGF6	MEGF6	367.3333333	0	3	0	0.68596712	FALSE	0	MEGF6	1132	0.35288462
792819	taxon:9606	3.10051993	1.60E-07	181315	1902	engrailed homeobox 1	gene	biological_process-&-1&-GO:1990403-&&-embryonic brain development-%%-GO:0009954-&&-proximal/distal pattern formation-%%-GO:0021549-&&-cerebellum development-%%-GO:0048666-&&-neuron development-%%-GO:0030917-&&-midbrain-hindbrain boundary development-%%-GO:0035115-&&-embryonic forelimb morphogenesis-%%-GO:0009953-&&-dorsal/ventral pattern formation-%%-GO:0030901-&&-midbrain development-%%-GO:0009653-&&-anatomical structure morphogenesis-%%-GO:0042756-&&-drinking behavior-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0035176-&&-social behavior-%%-GO:0035264-&&-multicellular organism growth-%%-GO:0043473-&&-pigmentation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0071542-&&-dopaminergic neuron differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0008344-&&-adult locomotory behavior-%%-GO:0001501-&&-skeletal system development-%%-GO:0061743-&&-motor learning|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:EN1	EN1	TRUE		EN1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EN1	0.32252655	0	3	5	FALSE	EN1	EN1	129	0	3	0	0.64991334	FALSE	0	EN1	352	0.35555556
792861	taxon:9606	3.305026	2.10E-07	164868	1902	fibulin 7	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005925-&&-focal adhesion-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0008201-&&-heparin binding-%%-GO:0005509-&&-calcium ion binding	G:9606:FBLN7				FBLN7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBLN7	0.30256948	0	3	5	FALSE	FBLN7	FBLN7	36.66666667	0	3	0	0.615829	FALSE	0	FBLN7	188	0.34627832
792865	taxon:9606	3.04616354	1.27E-06	164864	1902	chromosome 2 open reading frame 73	gene		G:9606:C2orf73				C2orf73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C2orf73	0.32828178	0	3	5	FALSE	C2orf73	C2orf73	155	0	3	0	0.65897274	FALSE	0	C2orf73	1266	0.34451902
792899	taxon:9606	3.13738774	2.40E-07	164819	1902	activator of HSP90 ATPase homolog 2	gene	biological_process-&-1&-GO:0032781-&&-positive regulation of ATPase activity|molecular_function-&-1&-GO:0051087-&&-chaperone binding-%%-GO:0001671-&&-ATPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:AHSA2				AHSA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AHSA2	0.3187365	0.33333333	3	5	FALSE	AHSA2	AHSA2	84	0	3	0	0.64376871	FALSE	0	AHSA2	232	0.35602837
792911	taxon:9606	2.9268946	2.34E-06	164786	1902	G protein-coupled receptor kinase 7	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0046777-&&-protein autophosphorylation-%%-GO:0007165-&&-signal transduction-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0097381-&&-photoreceptor disc membrane|molecular_function-&-1&-GO:0004703-&&-G-protein coupled receptor kinase activity-%%-GO:0050254-&&-rhodopsin kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:GRK7			KEGG-&-1&-hsa04144-&&-Endocytosis-%%-hsa04744-&&-Phototransduction-%%-hsa04062-&&-Chemokine signaling pathway	GRK7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRK7	0.34165904	0	3	5	FALSE	GRK7	GRK7	288.6666667	0	3	0	0.6788509	FALSE	0	GRK7	1530	0.3560231
792919	taxon:9606	3.07846227	5.87E-05	181155	1902	gamma-aminobutyric acid type A receptor alpha3 subunit	gene	biological_process-&-1&-GO:1902476-&&-chloride transmembrane transport-%%-GO:0006810-&&-transport-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0034707-&&-chloride channel complex-%%-GO:1902711-&&-GABA-A receptor complex|molecular_function-&-1&-GO:0005254-&&-chloride channel activity-%%-GO:0004890-&&-GABA-A receptor activity-%%-GO:0005230-&&-extracellular ligand-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0008503-&&-benzodiazepine receptor activity	G:9606:GABRA3	GABRA3	TRUE	KEGG-&-1&-hsa05032-&&-Morphine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GABRA3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABRA3	0.3248375	0	3	5	FALSE	GABRA3	GABRA3	122	0	3	0	0.65358962	FALSE	0	GABRA3	48888	0.3427762
793045	taxon:9606	3.75594769	3.90E-07	180841	1902	gastrin releasing peptide	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0007218-&&-neuropeptide signaling pathway|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005184-&&-neuropeptide hormone activity-%%-GO:0005102-&&-receptor binding	G:9606:GRP	GRP	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	GRP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GRP	0.26624439	0.33333333	3	5	FALSE	GRP	GRP	18	0	3	0	0.54067538	FALSE	0	GRP	266	0.42063492
793133	taxon:9606	3.59792028	3.00E-08	180674	1902	gap junction protein alpha 4	gene	biological_process-&-1&-GO:0048265-&&-response to pain-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0003158-&&-endothelium development-%%-GO:0006810-&&-transport-%%-GO:0001568-&&-blood vessel development-%%-GO:0007043-&&-cell-cell junction assembly-%%-GO:0006816-&&-calcium ion transport|cellular_component-&-1&-GO:0005921-&&-gap junction-%%-GO:0005922-&&-connexin complex-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:GJA4	GJA4	TRUE		GJA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GJA4	0.27793834	0.66666667	3	5	FALSE	GJA4	GJA4	21.66666667	0	3	0	0.56701329	FALSE	0	GJA4	50	0.51587302
793190	taxon:9606	3.3979833	3.10E-07	180556	1902	haptoglobin-related protein	gene	biological_process-&-1&-GO:0006898-&&-receptor-mediated endocytosis|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0034366-&&-spherical high-density lipoprotein particle-%%-GO:0070062-&&-extracellular exosome-%%-GO:0072562-&&-blood microparticle|molecular_function-&-1&-GO:0030492-&&-hemoglobin binding	G:9606:HPR			KEGG-&-1&-hsa05143-&&-African trypanosomiasis	HPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPR	0.29429221	0.33333333	3	5	FALSE	HPR	HPR	27.66666667	0	3	0	0.60033612	FALSE	0	HPR	130	0.34599156
793239	taxon:9606	3.23869545	0	180476	1902	5-hydroxytryptamine receptor 4	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0098664-&&-G-protein coupled serotonin receptor signaling pathway-%%-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0032098-&&-regulation of appetite-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005768-&&-endosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0001594-&&-trace-amine receptor activity-%%-GO:0004993-&&-G-protein coupled serotonin receptor activity	G:9606:HTR4			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	HTR4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTR4	0.3087663	0	3	5	FALSE	HTR4	HTR4	257	0	2	0	0.62688409	FALSE	1	HTR4	0	0
793295	taxon:9606	1	0	180363	1902	hyaluronan synthase 2	gene	biological_process-&-1&-GO:0085029-&&-extracellular matrix assembly-%%-GO:0036120-&&-cellular response to platelet-derived growth factor stimulus-%%-GO:0051549-&&-positive regulation of keratinocyte migration-%%-GO:1900127-&&-positive regulation of hyaluronan biosynthetic process-%%-GO:0044849-&&-estrous cycle-%%-GO:0090500-&&-endocardial cushion to mesenchymal transition-%%-GO:0045226-&&-extracellular polysaccharide biosynthetic process-%%-GO:0001570-&&-vasculogenesis-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030335-&&-positive regulation of cell migration-%%-GO:0060349-&&-bone morphogenesis-%%-GO:0071347-&&-cellular response to interleukin-1-%%-GO:0036302-&&-atrioventricular canal development-%%-GO:0030213-&&-hyaluronan biosynthetic process-%%-GO:0070295-&&-renal water absorption-%%-GO:0071498-&&-cellular response to fluid shear stress-%%-GO:0010838-&&-positive regulation of keratinocyte proliferation-%%-GO:0014911-&&-positive regulation of smooth muscle cell migration-%%-GO:0071356-&&-cellular response to tumor necrosis factor-%%-GO:0035810-&&-positive regulation of urine volume-%%-GO:1900625-&&-positive regulation of monocyte aggregation-%%-GO:0001822-&&-kidney development-%%-GO:1900026-&&-positive regulation of substrate adhesion-dependent cell spreading|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0050501-&&-hyaluronan synthase activity	G:9606:HAS2	HAS2	TRUE		HAS2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAS2	1	0	3	1	FALSE	HAS2	HAS2	1	0	2	0	1	FALSE	1	HAS2	0	0
793318	taxon:9606	3.07641405	1.92E-06	163938	1902	interleukin 23 receptor	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0042523-&&-positive regulation of tyrosine phosphorylation of Stat5 protein-%%-GO:0002827-&&-positive regulation of T-helper 1 type immune response-%%-GO:0032725-&&-positive regulation of granulocyte macrophage colony-stimulating factor production-%%-GO:0032729-&&-positive regulation of interferon-gamma production-%%-GO:0032819-&&-positive regulation of natural killer cell proliferation-%%-GO:0002230-&&-positive regulation of defense response to virus by host-%%-GO:0034341-&&-response to interferon-gamma-%%-GO:2000330-&&-positive regulation of T-helper 17 cell lineage commitment-%%-GO:0001916-&&-positive regulation of T cell mediated cytotoxicity-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0032735-&&-positive regulation of interleukin-12 production-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0043382-&&-positive regulation of memory T cell differentiation-%%-GO:0042510-&&-regulation of tyrosine phosphorylation of Stat1 protein-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0051135-&&-positive regulation of NK T cell activation-%%-GO:0006954-&&-inflammatory response-%%-GO:0038155-&&-interleukin-23-mediated signaling pathway-%%-GO:2000318-&&-positive regulation of T-helper 17 type immune response-%%-GO:0042520-&&-positive regulation of tyrosine phosphorylation of Stat4 protein-%%-GO:0010535-&&-positive regulation of activation of JAK2 kinase activity-%%-GO:0042102-&&-positive regulation of T cell proliferation-%%-GO:0032740-&&-positive regulation of interleukin-17 production-%%-GO:0032693-&&-negative regulation of interleukin-10 production-%%-GO:0042104-&&-positive regulation of activated T cell proliferation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0072536-&&-interleukin-23 receptor complex-%%-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0042020-&&-interleukin-23 receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0005143-&&-interleukin-12 receptor binding-%%-GO:0042019-&&-interleukin-23 binding	G:9606:IL23R			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa05321-&&-Inflammatory bowel disease (IBD)-%%-hsa04659-&&-Th17 cell differentiation-%%-hsa05200-&&-Pathways in cancer-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL23R	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL23R	0.32505377	0.33333333	3	5	FALSE	IL23R	IL23R	129.6666667	0	3	0	0.65393099	FALSE	0	IL23R	1384	0.37487923
793328	taxon:9606	2.91444777	2.42E-06	163930	1902	PDLIM1 interacting kinase 1 like	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:PDIK1L				PDIK1L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PDIK1L	0.34311817	0.33333333	3	5	FALSE	PDIK1L	PDIK1L	328.6666667	0	3	0	0.68092537	FALSE	0	PDIK1L	6954	0.39087302
793368	taxon:9606	3.05656216	4.20E-07	180229	1902	integrin subunit alpha D	gene	biological_process-&-1&-GO:0006955-&&-immune response-%%-GO:0030198-&&-extracellular matrix organization-%%-GO:0034113-&&-heterotypic cell-cell adhesion-%%-GO:0007229-&&-integrin-mediated signaling pathway|cellular_component-&-1&-GO:0009986-&&-cell surface-%%-GO:0005886-&&-plasma membrane-%%-GO:0008305-&&-integrin complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:ITGAD			KEGG-&-1&-hsa04810-&&-Regulation of actin cytoskeleton	ITGAD	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ITGAD	0.32716495	0.33333333	3	5	FALSE	ITGAD	ITGAD	174	0	3	0	0.65723964	FALSE	0	ITGAD	728	0.34052288
787145	taxon:9606	3.33543406	2.10E-07	179985	1902	lipase C, hepatic type	gene	biological_process-&-1&-GO:0019433-&&-triglyceride catabolic process-%%-GO:0006633-&&-fatty acid biosynthetic process-%%-GO:0034375-&&-high-density lipoprotein particle remodeling-%%-GO:0034638-&&-phosphatidylcholine catabolic process-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0044241-&&-lipid digestion-%%-GO:0070328-&&-triglyceride homeostasis-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0034374-&&-low-density lipoprotein particle remodeling-%%-GO:0034372-&&-very-low-density lipoprotein particle remodeling-%%-GO:0043691-&&-reverse cholesterol transport-%%-GO:0034373-&&-intermediate-density lipoprotein particle remodeling-%%-GO:0034382-&&-chylomicron remnant clearance|cellular_component-&-1&-GO:0034364-&&-high-density lipoprotein particle-%%-GO:0005576-&&-extracellular region-%%-GO:0005615-&&-extracellular space-%%-GO:0005788-&&-endoplasmic reticulum lumen|molecular_function-&-1&-GO:0004806-&&-triglyceride lipase activity-%%-GO:0008201-&&-heparin binding-%%-GO:0004620-&&-phospholipase activity-%%-GO:0030169-&&-low-density lipoprotein particle binding-%%-GO:0034185-&&-apolipoprotein binding	G:9606:LIPC	LIPC	TRUE	KEGG-&-1&-hsa04979-&&-Cholesterol metabolism-%%-hsa00561-&&-Glycerolipid metabolism-%%-hsa01100-&&-Metabolic pathways	LIPC	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LIPC	0.29981105	0	2	5	FALSE	LIPC	LIPC	55	0	2	0	0.61076099	FALSE	0	LIPC	222	0.52427184
787194	taxon:9606	3.28470143	8.00E-08	163512	1902	sperm acrosome associated 4	gene	biological_process-&-1&-GO:0006501-&&-C-terminal protein lipidation-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0001669-&&-acrosomal vesicle	G:9606:SPACA4				SPACA4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPACA4	0.30444167	0	2	5	FALSE	SPACA4	SPACA4	62.5	0	2	0	0.61921643	FALSE	0	SPACA4	86	0.50409836
787225	taxon:9606	3.40318261	0	163451	1902	transcription elongation factor B subunit 3C	gene	biological_process-&-1&-GO:0006368-&&-transcription elongation from RNA polymerase II promoter-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005654-&&-nucleoplasm-%%-GO:0070449-&&-elongin complex	G:9606:TCEB3C				TCEB3C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TCEB3C	0.29384259	1	2	5	FALSE	TCEB3C	TCEB3C	88	0	2	0	0.59946957	FALSE	0	TCEB3C	0	0.70967742
787277	taxon:9606	2.96391996	9.00E-07	179753	1902	potassium voltage-gated channel modifier subfamily G member 1	gene	biological_process-&-1&-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0051260-&&-protein homooligomerization-%%-GO:0006813-&&-potassium ion transport-%%-GO:1902259-&&-regulation of delayed rectifier potassium channel activity|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0005267-&&-potassium channel activity	G:9606:KCNG1				KCNG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNG1	0.33739103	0	2	5	FALSE	KCNG1	KCNG1	335.5	0	2	0	0.67268001	FALSE	0	KCNG1	912	0.50300752
787291	taxon:9606	3.11737829	1.80E-07	179725	1902	potassium voltage-gated channel subfamily Q member 2	gene	biological_process-&-1&-GO:0007268-&&-chemical synaptic transmission-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0007399-&&-nervous system development-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0043194-&&-axon initial segment-%%-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0033268-&&-node of Ranvier-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005267-&&-potassium channel activity-%%-GO:0005249-&&-voltage-gated potassium channel activity-%%-GO:0030506-&&-ankyrin binding	G:9606:KCNQ2			KEGG-&-1&-hsa04725-&&-Cholinergic synapse	KCNQ2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNQ2	0.32078237	0	2	5	FALSE	KCNQ2	KCNQ2	149.5	0	2	0	0.64710362	FALSE	0	KCNQ2	204	0.50510204
787325	taxon:9606	3.05798015	7.00E-08	163277	1902	zinc finger and BTB domain containing 7C	gene	biological_process-&-1&-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:1903025-&&-regulation of RNA polymerase II regulatory region sequence-specific DNA binding-%%-GO:0045600-&&-positive regulation of fat cell differentiation|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003676-&&-nucleic acid binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZBTB7C				ZBTB7C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZBTB7C	0.32701324	0	2	5	FALSE	ZBTB7C	ZBTB7C	255.5	0	2	0	0.65700331	FALSE	0	ZBTB7C	270	0.50496032
787373	taxon:9606	3.14983457	2.50E-07	163159	1902	eukaryotic elongation factor 2 lysine methyltransferase	gene	biological_process-&-1&-GO:0006479-&&-protein methylation-%%-GO:0018023-&&-peptidyl-lysine trimethylation|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0016279-&&-protein-lysine N-methyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:EEF2KMT				EEF2KMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EEF2KMT	0.31747699	0	2	5	FALSE	EEF2KMT	EEF2KMT	87.5	0	2	0	0.64169424	FALSE	0	EEF2KMT	294	0.5
787423	taxon:9606	3.00094533	6.00E-08	179457	1902	lactase	gene	biological_process-&-1&-GO:1901657-&&-glycosyl compound metabolic process-%%-GO:0044245-&&-polysaccharide digestion-%%-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0016020-&&-membrane-%%-GO:0016324-&&-apical plasma membrane|molecular_function-&-1&-GO:0017042-&&-glycosylceramidase activity-%%-GO:0000016-&&-lactase activity-%%-GO:0008422-&&-beta-glucosidase activity	G:9606:LCT			KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04973-&&-Carbohydrate digestion and absorption	LCT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCT	0.33322833	0	2	5	FALSE	LCT	LCT	249	0	2	0	0.66650911	FALSE	0	LCT	286	0.51666667
787488	taxon:9606	3.47817867	4.90E-07	162960	1902	sodium leak channel, non-selective	gene	biological_process-&-1&-GO:0035725-&&-sodium ion transmembrane transport-%%-GO:0006816-&&-calcium ion transport-%%-GO:0070588-&&-calcium ion transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0060075-&&-regulation of resting membrane potential-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0086010-&&-membrane depolarization during action potential-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005272-&&-sodium channel activity-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005261-&&-cation channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0022840-&&-leak channel activity	G:9606:NALCN				NALCN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NALCN	0.28750679	0	2	5	FALSE	NALCN	NALCN	52	0	2	0	0.58697022	FALSE	0	NALCN	282	0.5049505
787753	taxon:9606	2.87096266	0	178836	1902	POU class 4 homeobox 1	gene	biological_process-&-1&-GO:2001208-&&-negative regulation of transcription elongation from RNA polymerase I promoter-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0060384-&&-innervation-%%-GO:0007416-&&-synapse assembly-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0021559-&&-trigeminal nerve development-%%-GO:0043069-&&-negative regulation of programmed cell death-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0031175-&&-neuron projection development-%%-GO:0021953-&&-central nervous system neuron differentiation-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071158-&&-positive regulation of cell cycle arrest-%%-GO:0048665-&&-neuron fate specification-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0051355-&&-proprioception involved in equilibrioception-%%-GO:0001967-&&-suckling behavior-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0003223-&&-ventricular compact myocardium morphogenesis-%%-GO:0007409-&&-axonogenesis-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0010628-&&-positive regulation of gene expression-%%-GO:0048935-&&-peripheral nervous system neuron development-%%-GO:0021986-&&-habenula development-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0021535-&&-cell migration in hindbrain-%%-GO:0043524-&&-negative regulation of neuron apoptotic process-%%-GO:0071345-&&-cellular response to cytokine stimulus-%%-GO:0007498-&&-mesoderm development-%%-GO:0048880-&&-sensory system development|cellular_component-&-1&-GO:0043005-&&-neuron projection-%%-GO:0000790-&&-nuclear chromatin-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0043565-&&-sequence-specific DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0051020-&&-GTPase binding-%%-GO:0003705-&&-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0003697-&&-single-stranded DNA binding-%%-GO:0001205-&&-transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding-%%-GO:0003682-&&-chromatin binding-%%-GO:0000980-&&-RNA polymerase II distal enhancer sequence-specific DNA binding	G:9606:POU4F1				POU4F1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU4F1	0.34831522	1	2	4	FALSE	POU4F1	POU4F1	588.5	0	2	0	0.68817289	FALSE	0	POU4F1	0	0.54897388
787820	taxon:9606	2.96281708	9.80E-07	162361	1902	F-box and leucine rich repeat protein 13	gene	biological_process-&-1&-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004842-&&-ubiquitin-protein transferase activity	G:9606:FBXL13				FBXL13	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXL13	0.33751662	0	2	5	FALSE	FBXL13	FBXL13	337.5	0	2	0	0.67286382	FALSE	0	FBXL13	822	0.50223881
787911	taxon:9606	2.94312274	3.90E-07	162240	1902	transmembrane p24 trafficking protein family member 8	gene	biological_process-&-1&-GO:0006810-&&-transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:TMED8				TMED8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMED8	0.33977516	0	2	5	FALSE	TMED8	TMED8	439.5	0	2	0	0.67614621	FALSE	0	TMED8	1592	0.51226636
787926	taxon:9606	3.65070112	0	178590	1902	ornithine decarboxylase antizyme 2	gene	biological_process-&-1&-GO:0045732-&&-positive regulation of protein catabolic process-%%-GO:0006596-&&-polyamine biosynthetic process-%%-GO:0006595-&&-polyamine metabolic process-%%-GO:0043086-&&-negative regulation of catalytic activity-%%-GO:1902268-&&-negative regulation of polyamine transmembrane transport-%%-GO:0090316-&&-positive regulation of intracellular protein transport-%%-GO:0006521-&&-regulation of cellular amino acid metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0008073-&&-ornithine decarboxylase inhibitor activity	G:9606:OAZ2				OAZ2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-OAZ2	0.27391999	1	2	5	FALSE	OAZ2	OAZ2	18	0	2	0	0.55821648	FALSE	0	OAZ2	0	0.54545455
788514	taxon:9606	2.97463369	3.00E-08	177526	1902	SRY-box 1	gene	biological_process-&-1&-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0001764-&&-neuron migration-%%-GO:0021521-&&-ventral spinal cord interneuron specification-%%-GO:0002089-&&-lens morphogenesis in camera-type eye-%%-GO:0021884-&&-forebrain neuron development-%%-GO:0006325-&&-chromatin organization|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001046-&&-core promoter sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003677-&&-DNA binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0005515-&&-protein binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SOX1				SOX1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOX1	0.33617585	0	2	5	FALSE	SOX1	SOX1	297	0	2	0	0.67089439	FALSE	0	SOX1	188	0.54014599
788558	taxon:9606	2.93303923	4.10E-07	161056	1902	zinc finger DHHC-type containing 21	gene	biological_process-&-1&-GO:0018230-&&-peptidyl-L-cysteine S-palmitoylation-%%-GO:0048733-&&-sebaceous gland development-%%-GO:0018345-&&-protein palmitoylation-%%-GO:0050999-&&-regulation of nitric-oxide synthase activity-%%-GO:0001942-&&-hair follicle development|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0016409-&&-palmitoyltransferase activity-%%-GO:0019706-&&-protein-cysteine S-palmitoyltransferase activity	G:9606:ZDHHC21				ZDHHC21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZDHHC21	0.34094327	0	2	5	FALSE	ZDHHC21	ZDHHC21	414.5	0	2	0	0.67782679	FALSE	0	ZDHHC21	1298	0.5067402
788644	taxon:9606	2.8440208	0	160873	1902	NLR family pyrin domain containing 10	gene	biological_process-&-1&-GO:0050832-&&-defense response to fungus-%%-GO:0045087-&&-innate immune response-%%-GO:0035397-&&-helper T cell enhancement of adaptive immune response-%%-GO:2000778-&&-positive regulation of interleukin-6 secretion-%%-GO:2000318-&&-positive regulation of T-helper 17 type immune response-%%-GO:0002250-&&-adaptive immune response-%%-GO:0002827-&&-positive regulation of T-helper 1 type immune response-%%-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0036336-&&-dendritic cell migration-%%-GO:2000484-&&-positive regulation of interleukin-8 secretion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0019897-&&-extrinsic component of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:NLRP10				NLRP10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NLRP10	0.35161487	1	2	5	FALSE	NLRP10	NLRP10	637	0	2	0	0.6926632	FALSE	0	NLRP10	0	0.53216374
788676	taxon:9606	3.71230503	0	177218	1902	TIMP metallopeptidase inhibitor 4	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity-%%-GO:0007219-&&-Notch signaling pathway-%%-GO:0043434-&&-response to peptide hormone-%%-GO:0009725-&&-response to hormone-%%-GO:0032496-&&-response to lipopolysaccharide-%%-GO:0034097-&&-response to cytokine-%%-GO:0008150-&&-biological_process-%%-GO:0051045-&&-negative regulation of membrane protein ectodomain proteolysis-%%-GO:0042698-&&-ovulation cycle-%%-GO:0042493-&&-response to drug-%%-GO:0007417-&&-central nervous system development-%%-GO:0043086-&&-negative regulation of catalytic activity|cellular_component-&-1&-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space-%%-GO:0030017-&&-sarcomere|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008191-&&-metalloendopeptidase inhibitor activity-%%-GO:0002020-&&-protease binding	G:9606:TIMP4	TIMP4	TRUE		TIMP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TIMP4	0.26937442	1	2	5	FALSE	TIMP4	TIMP4	33	0	2	0	0.54794916	FALSE	0	TIMP4	0	0.58928571
788756	taxon:9606	2.90893335	7.00E-08	177001	1902	zinc finger protein 142	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0008150-&&-biological_process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0003674-&&-molecular_function-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF142				ZNF142	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF142	0.34376862	0	2	4	FALSE	ZNF142	ZNF142	482	0	2	0	0.68184444	FALSE	0	ZNF142	498	0.51388889
788766	taxon:9606	2.96754372	2.87E-06	176965	1902	zinc finger protein 215	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF215				ZNF215	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF215	0.33697903	0	2	5	FALSE	ZNF215	ZNF215	330.5	0	2	0	0.67207605	FALSE	0	ZNF215	1554	0.50075988
788831	taxon:9606	3.64802269	4.40E-07	176793	1902	uncoupling protein 1	gene	biological_process-&-1&-GO:0071398-&&-cellular response to fatty acid-%%-GO:0050873-&&-brown fat cell differentiation-%%-GO:1903426-&&-regulation of reactive oxygen species biosynthetic process-%%-GO:0034614-&&-cellular response to reactive oxygen species-%%-GO:0009409-&&-response to cold-%%-GO:0009266-&&-response to temperature stimulus-%%-GO:0031667-&&-response to nutrient levels-%%-GO:1990845-&&-adaptive thermogenesis-%%-GO:0002024-&&-diet induced thermogenesis-%%-GO:1990542-&&-mitochondrial transmembrane transport-%%-GO:0015992-&&-proton transport-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0017077-&&-oxidative phosphorylation uncoupler activity-%%-GO:1901612-&&-cardiolipin binding-%%-GO:0036041-&&-long-chain fatty acid binding-%%-GO:0032555-&&-purine ribonucleotide binding-%%-GO:0022857-&&-transmembrane transporter activity	G:9606:UCP1			KEGG-&-1&-hsa04714-&&-Thermogenesis-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa05016-&&-Huntington disease-%%-hsa03320-&&-PPAR signaling pathway	UCP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UCP1	0.2741211	0	2	5	FALSE	UCP1	UCP1	21.5	0	2	0	0.55866289	FALSE	0	UCP1	420	0.5
788835	taxon:9606	3.80226879	2.70E-07	176782	1902	UDP glucuronosyltransferase family 2 member B7	gene	biological_process-&-1&-GO:0008209-&&-androgen metabolic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0052695-&&-cellular glucuronidation|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031090-&&-organelle membrane-%%-GO:0016020-&&-membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015020-&&-glucuronosyltransferase activity-%%-GO:0001972-&&-retinoic acid binding	G:9606:UGT2B7	UGT2B7	TRUE	KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa00830-&&-Retinol metabolism-%%-hsa05204-&&-Chemical carcinogenesis	UGT2B7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UGT2B7	0.26300087	0	2	5	FALSE	UGT2B7	UGT2B7	7	0	2	0	0.5329552	FALSE	0	UGT2B7	182	0.5
788883	taxon:9606	3.28816764	4.00E-08	176684	1902	Wnt family member 9B	gene	biological_process-&-1&-GO:0072181-&&-mesonephric duct formation-%%-GO:1902455-&&-negative regulation of stem cell population maintenance-%%-GO:0001932-&&-regulation of protein phosphorylation-%%-GO:0007275-&&-multicellular organism development-%%-GO:0061303-&&-cornea development in camera-type eye-%%-GO:0001701-&&-in utero embryonic development-%%-GO:0030539-&&-male genitalia development-%%-GO:0071300-&&-cellular response to retinoic acid-%%-GO:0001658-&&-branching involved in ureteric bud morphogenesis-%%-GO:0072046-&&-establishment of planar polarity involved in nephron morphogenesis-%%-GO:0043085-&&-positive regulation of catalytic activity-%%-GO:0060070-&&-canonical Wnt signaling pathway-%%-GO:1905438-&&-non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation-%%-GO:0060071-&&-Wnt signaling pathway, planar cell polarity pathway-%%-GO:0072003-&&-kidney rudiment formation-%%-GO:0048701-&&-embryonic cranial skeleton morphogenesis-%%-GO:0072038-&&-mesenchymal stem cell maintenance involved in nephron morphogenesis-%%-GO:0072044-&&-collecting duct development-%%-GO:0003339-&&-regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis-%%-GO:0045165-&&-cell fate commitment-%%-GO:1904948-&&-midbrain dopaminergic neuron differentiation-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0016055-&&-Wnt signaling pathway-%%-GO:0007267-&&-cell-cell signaling-%%-GO:0060021-&&-palate development-%%-GO:0009786-&&-regulation of asymmetric cell division-%%-GO:0072174-&&-metanephric tubule formation-%%-GO:0061038-&&-uterus morphogenesis-%%-GO:0009267-&&-cellular response to starvation-%%-GO:0030182-&&-neuron differentiation-%%-GO:0035150-&&-regulation of tube size|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0005578-&&-proteinaceous extracellular matrix-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0005109-&&-frizzled binding-%%-GO:0039706-&&-co-receptor binding	G:9606:WNT9B			KEGG-&-1&-hsa04310-&&-Wnt signaling pathway-%%-hsa04390-&&-Hippo signaling pathway-%%-hsa04916-&&-Melanogenesis-%%-hsa05224-&&-Breast cancer-%%-hsa04934-&&-Cushing syndrome-%%-hsa05165-&&-Human papillomavirus infection-%%-hsa05205-&&-Proteoglycans in cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04150-&&-mTOR signaling pathway-%%-hsa05217-&&-Basal cell carcinoma-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05226-&&-Gastric cancer	WNT9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WNT9B	0.30412075	0	2	5	FALSE	WNT9B	WNT9B	49.5	0	2	0	0.61863873	FALSE	0	WNT9B	38	0.50520833
788887	taxon:9606	3.01764613	1.45E-06	176674	1902	xanthine dehydrogenase	gene	biological_process-&-1&-GO:0001933-&&-negative regulation of protein phosphorylation-%%-GO:0006919-&&-activation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:2000379-&&-positive regulation of reactive oxygen species metabolic process-%%-GO:1900745-&&-positive regulation of p38MAPK cascade-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0001937-&&-negative regulation of endothelial cell proliferation-%%-GO:0007595-&&-lactation-%%-GO:0045602-&&-negative regulation of endothelial cell differentiation-%%-GO:0006195-&&-purine nucleotide catabolic process-%%-GO:0009115-&&-xanthine catabolic process-%%-GO:1900747-&&-negative regulation of vascular endothelial growth factor signaling pathway-%%-GO:0010629-&&-negative regulation of gene expression-%%-GO:2001213-&&-negative regulation of vasculogenesis-%%-GO:0051898-&&-negative regulation of protein kinase B signaling|cellular_component-&-1&-GO:0016529-&&-sarcoplasmic reticulum-%%-GO:0005777-&&-peroxisome-%%-GO:0005829-&&-cytosol-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0051537-&&-2 iron, 2 sulfur cluster binding-%%-GO:0005506-&&-iron ion binding-%%-GO:0050660-&&-flavin adenine dinucleotide binding-%%-GO:0004854-&&-xanthine dehydrogenase activity-%%-GO:0004855-&&-xanthine oxidase activity-%%-GO:0043546-&&-molybdopterin cofactor binding-%%-GO:0009055-&&-electron carrier activity-%%-GO:0016614-&&-oxidoreductase activity, acting on CH-OH group of donors-%%-GO:0016903-&&-oxidoreductase activity, acting on the aldehyde or oxo group of donors-%%-GO:0042803-&&-protein homodimerization activity	G:9606:XDH	XDH	TRUE	KEGG-&-1&-hsa04146-&&-Peroxisome-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00232-&&-Caffeine metabolism-%%-hsa00230-&&-Purine metabolism	XDH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XDH	0.33138412	0	2	4	FALSE	XDH	XDH	298.5	0	2	0	0.66372564	FALSE	0	XDH	768	0.50084175
788928	taxon:9606	2.97936033	5.00E-08	176582	1902	sterol O-acyltransferase 2	gene	biological_process-&-1&-GO:0010742-&&-macrophage derived foam cell differentiation-%%-GO:0030299-&&-intestinal cholesterol absorption-%%-GO:0033344-&&-cholesterol efflux-%%-GO:0034379-&&-very-low-density lipoprotein particle assembly-%%-GO:0042632-&&-cholesterol homeostasis-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0008203-&&-cholesterol metabolic process-%%-GO:0034435-&&-cholesterol esterification|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005903-&&-brush border-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015485-&&-cholesterol binding-%%-GO:0000062-&&-fatty-acyl-CoA binding-%%-GO:0034736-&&-cholesterol O-acyltransferase activity-%%-GO:0016746-&&-transferase activity, transferring acyl groups	G:9606:SOAT2	SOAT2	TRUE	KEGG-&-1&-hsa00100-&&-Steroid biosynthesis-%%-hsa04979-&&-Cholesterol metabolism	SOAT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SOAT2	0.33564252	0	2	5	FALSE	SOAT2	SOAT2	308.5	0	2	0	0.67010661	FALSE	0	SOAT2	236	0.5265411
788980	taxon:9606	3.89002678	0	160094	1902	C1q and tumor necrosis factor related protein 9B	gene	cellular_component-&-1&-GO:0005581-&&-collagen trimer-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C1QTNF9B				C1QTNF9B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C1QTNF9B	0.25706764	1	2	5	FALSE	C1QTNF9B	C1QTNF9B	15	0	2	0	0.51832887	FALSE	0	C1QTNF9B	0	0.53571429
789033	taxon:9606	3.71262014	1.80E-07	176322	1902	collagen like tail subunit of asymmetric acetylcholinesterase	gene	biological_process-&-1&-GO:0008582-&&-regulation of synaptic growth at neuromuscular junction-%%-GO:0090150-&&-establishment of protein localization to membrane-%%-GO:0001507-&&-acetylcholine catabolic process in synaptic cleft-%%-GO:0071340-&&-skeletal muscle acetylcholine-gated channel clustering-%%-GO:0008105-&&-asymmetric protein localization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0005581-&&-collagen trimer-%%-GO:0005615-&&-extracellular space-%%-GO:0005605-&&-basal lamina-%%-GO:0043083-&&-synaptic cleft-%%-GO:0031594-&&-neuromuscular junction|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:COLQ				COLQ	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-COLQ	0.26935155	0	2	5	FALSE	COLQ	COLQ	8	0	2	0	0.54789664	FALSE	0	COLQ	26	0.5
789128	taxon:9606	3.63415787	0	176145	1902	maltase-glucoamylase	gene	biological_process-&-1&-GO:0005983-&&-starch catabolic process-%%-GO:0000023-&&-maltose metabolic process-%%-GO:0043312-&&-neutrophil degranulation-%%-GO:0044245-&&-polysaccharide digestion|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005886-&&-plasma membrane-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0070821-&&-tertiary granule membrane-%%-GO:0101003-&&-ficolin-1-rich granule membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding-%%-GO:0032450-&&-maltose alpha-glucosidase activity-%%-GO:0016160-&&-amylase activity-%%-GO:0004339-&&-glucan 1,4-alpha-glucosidase activity-%%-GO:0003824-&&-catalytic activity-%%-GO:0004558-&&-alpha-1,4-glucosidase activity	G:9606:MGAM	MGAM	TRUE	KEGG-&-1&-hsa00052-&&-Galactose metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00500-&&-Starch and sucrose metabolism	MGAM	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGAM	0.27516691	1	2	5	FALSE	MGAM	MGAM	45	0	2	0	0.56097369	FALSE	0	MGAM	0	1
789154	taxon:9606	3.08066803	0	159707	1902	hes family bHLH transcription factor 5	gene	biological_process-&-1&-GO:0007219-&&-Notch signaling pathway-%%-GO:0090162-&&-establishment of epithelial cell polarity-%%-GO:0072282-&&-metanephric nephron tubule morphogenesis-%%-GO:0042668-&&-auditory receptor cell fate determination-%%-GO:0007420-&&-brain development-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0048715-&&-negative regulation of oligodendrocyte differentiation-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0048469-&&-cell maturation-%%-GO:0050678-&&-regulation of epithelial cell proliferation-%%-GO:0045607-&&-regulation of auditory receptor cell differentiation-%%-GO:0045747-&&-positive regulation of Notch signaling pathway-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0042491-&&-auditory receptor cell differentiation-%%-GO:0021915-&&-neural tube development-%%-GO:0007224-&&-smoothened signaling pathway-%%-GO:0022010-&&-central nervous system myelination-%%-GO:0072049-&&-comma-shaped body morphogenesis-%%-GO:0006461-&&-protein complex assembly-%%-GO:0002062-&&-chondrocyte differentiation-%%-GO:0007155-&&-cell adhesion-%%-GO:0042517-&&-positive regulation of tyrosine phosphorylation of Stat3 protein-%%-GO:0014003-&&-oligodendrocyte development-%%-GO:0060122-&&-inner ear receptor stereocilium organization-%%-GO:0045595-&&-regulation of cell differentiation-%%-GO:0097150-&&-neuronal stem cell population maintenance-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0030513-&&-positive regulation of BMP signaling pathway-%%-GO:2000974-&&-negative regulation of pro-B cell differentiation-%%-GO:0021537-&&-telencephalon development-%%-GO:0031641-&&-regulation of myelination-%%-GO:0043010-&&-camera-type eye development-%%-GO:0045665-&&-negative regulation of neuron differentiation-%%-GO:2000737-&&-negative regulation of stem cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0048708-&&-astrocyte differentiation-%%-GO:0050767-&&-regulation of neurogenesis-%%-GO:0072050-&&-S-shaped body morphogenesis-%%-GO:0072086-&&-specification of loop of Henle identity-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:2000981-&&-negative regulation of inner ear receptor cell differentiation-%%-GO:0021861-&&-forebrain radial glial cell differentiation-%%-GO:0051216-&&-cartilage development-%%-GO:0048712-&&-negative regulation of astrocyte differentiation-%%-GO:0021781-&&-glial cell fate commitment-%%-GO:0048661-&&-positive regulation of smooth muscle cell proliferation-%%-GO:2000978-&&-negative regulation of forebrain neuron differentiation|cellular_component-&-1&-GO:0005575-&&-cellular_component-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003690-&&-double-stranded DNA binding-%%-GO:0008134-&&-transcription factor binding-%%-GO:0046983-&&-protein dimerization activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003682-&&-chromatin binding	G:9606:HES5			KEGG-&-1&-hsa04330-&&-Notch signaling pathway-%%-hsa05224-&&-Breast cancer-%%-hsa05200-&&-Pathways in cancer-%%-hsa05165-&&-Human papillomavirus infection	HES5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HES5	0.32460492	1	2	5	FALSE	HES5	HES5	189	0	2	0	0.65322199	FALSE	0	HES5	0	0.5625
789339	taxon:9606	3.74854262	3.00E-07	175704	1902	SEC22 homolog C, vesicle trafficking protein	gene	biological_process-&-1&-GO:0006887-&&-exocytosis-%%-GO:0015031-&&-protein transport-%%-GO:0006888-&&-ER to Golgi vesicle-mediated transport-%%-GO:0048280-&&-vesicle fusion with Golgi apparatus|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031201-&&-SNARE complex|molecular_function-&-1&-GO:0005484-&&-SNAP receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0000149-&&-SNARE binding	G:9606:SEC22C				SEC22C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC22C	0.26677034	0	2	5	FALSE	SEC22C	SEC22C	17.5	0	2	0	0.54190956	FALSE	0	SEC22C	98	0.5
789396	taxon:9606	3.03718292	0	175574	1902	adhesion G protein-coupled receptor G1	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0010573-&&-vascular endothelial growth factor production-%%-GO:0070528-&&-protein kinase C signaling-%%-GO:0035025-&&-positive regulation of Rho protein signal transduction-%%-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:0007420-&&-brain development-%%-GO:0016477-&&-cell migration-%%-GO:0021796-&&-cerebral cortex regionalization-%%-GO:0007266-&&-Rho protein signal transduction-%%-GO:2000179-&&-positive regulation of neural precursor cell proliferation-%%-GO:0001525-&&-angiogenesis-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0021819-&&-layer formation in cerebral cortex-%%-GO:2001223-&&-negative regulation of neuron migration-%%-GO:0072520-&&-seminiferous tubule development-%%-GO:0045785-&&-positive regulation of cell adhesion-%%-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0021801-&&-cerebral cortex radial glia guided migration-%%-GO:0007155-&&-cell adhesion|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0016021-&&-integral component of membrane-%%-GO:0097451-&&-glial limiting end-foot|molecular_function-&-1&-GO:0050840-&&-extracellular matrix binding-%%-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0005518-&&-collagen binding-%%-GO:0008201-&&-heparin binding	G:9606:ADGRG1				ADGRG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADGRG1	0.32925248	1	2	5	FALSE	ADGRG1	ADGRG1	279.5	0	2	0	0.66046951	FALSE	0	ADGRG1	0	0.53339695
789407	taxon:9606	3.14447771	8.00E-08	159163	1902	von Hippel-Lindau tumor suppressor like	gene	biological_process-&-1&-GO:0016567-&&-protein ubiquitination|cellular_component-&-1&-GO:0030891-&&-VCB complex-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0005515-&&-protein binding	G:9606:VHLL				VHLL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-VHLL	0.31801784	0	2	5	FALSE	VHLL	VHLL	127	0	2	0	0.64258705	FALSE	0	VHLL	102	0.50806452
789458	taxon:9606	3.24405231	0	175427	1902	neuregulin 2	gene	biological_process-&-1&-GO:0014066-&&-regulation of phosphatidylinositol 3-kinase signaling-%%-GO:0046854-&&-phosphatidylinositol phosphorylation-%%-GO:2000145-&&-regulation of cell motility-%%-GO:0007165-&&-signal transduction-%%-GO:0038128-&&-ERBB2 signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:1901185-&&-negative regulation of ERBB signaling pathway-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005102-&&-receptor binding-%%-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0046934-&&-phosphatidylinositol-4,5-bisphosphate 3-kinase activity-%%-GO:0008083-&&-growth factor activity-%%-GO:0004713-&&-protein tyrosine kinase activity	G:9606:NRG2			KEGG-&-1&-hsa04012-&&-ErbB signaling pathway-%%-hsa01521-&&-EGFR tyrosine kinase inhibitor resistance	NRG2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NRG2	0.30825644	1	2	5	FALSE	NRG2	NRG2	105.5	0	2	0	0.62599128	FALSE	0	NRG2	0	0.5672043
789495	taxon:9606	2.96124153	0	158952	1902	SH2 domain containing 5	gene	cellular_component-&-1&-GO:0014069-&&-postsynaptic density-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane	G:9606:SH2D5				SH2D5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH2D5	0.3376962	1	2	5	FALSE	SH2D5	SH2D5	383.5	0	2	0	0.67312641	FALSE	0	SH2D5	0	0.55259366
789528	taxon:9606	3.07688672	6.00E-08	175258	1902	mucin 12, cell surface associated	gene	biological_process-&-1&-GO:0016266-&&-O-glycan processing-%%-GO:0001558-&&-regulation of cell growth-%%-GO:0002223-&&-stimulatory C-type lectin receptor signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005796-&&-Golgi lumen|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:MUC12				MUC12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MUC12	0.32500384	0	2	5	FALSE	MUC12	MUC12	193.5	0	2	0	0.65385221	FALSE	0	MUC12	228	0.52027027
789550	taxon:9606	2.87757996	8.00E-08	175203	1902	KIAA0087 lncRNA	gene		G:9606:KIAA0087				KIAA0087	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIAA0087	0.34751424	0	2	5	FALSE	KIAA0087	KIAA0087	541.5	0	2	0	0.68707001	FALSE	0	KIAA0087	294	0.51378327
789600	taxon:9606	3.48322042	3.20E-07	175091	1902	purinergic receptor P2Y14	gene	biological_process-&-1&-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0035589-&&-G-protein coupled purinergic nucleotide receptor signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0045028-&&-G-protein coupled purinergic nucleotide receptor activity-%%-GO:0045029-&&-UDP-activated nucleotide receptor activity	G:9606:P2RY14			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	P2RY14	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-P2RY14	0.28709065	0	2	5	FALSE	P2RY14	P2RY14	36.5	0	2	0	0.58612993	FALSE	0	P2RY14	118	0.5
789620	taxon:9606	3.44083819	1.00E-07	175041	1902	potassium voltage-gated channel subfamily E regulatory subunit 2	gene	biological_process-&-1&-GO:0035690-&&-cellular response to drug-%%-GO:1901387-&&-positive regulation of voltage-gated calcium channel activity-%%-GO:0060306-&&-regulation of membrane repolarization-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0043586-&&-tongue development-%%-GO:0086005-&&-ventricular cardiac muscle cell action potential-%%-GO:0086011-&&-membrane repolarization during action potential-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0086002-&&-cardiac muscle cell action potential involved in contraction-%%-GO:1902259-&&-regulation of delayed rectifier potassium channel activity-%%-GO:0010107-&&-potassium ion import-%%-GO:0007568-&&-aging-%%-GO:0086091-&&-regulation of heart rate by cardiac conduction-%%-GO:1901979-&&-regulation of inward rectifier potassium channel activity-%%-GO:1902260-&&-negative regulation of delayed rectifier potassium channel activity-%%-GO:0061337-&&-cardiac conduction-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:0071435-&&-potassium ion export-%%-GO:0086009-&&-membrane repolarization-%%-GO:0060307-&&-regulation of ventricular cardiac muscle cell membrane repolarization-%%-GO:0098915-&&-membrane repolarization during ventricular cardiac muscle cell action potential-%%-GO:1902159-&&-regulation of cyclic nucleotide-gated ion channel activity|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005886-&&-plasma membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005764-&&-lysosome|molecular_function-&-1&-GO:0044325-&&-ion channel binding-%%-GO:0005251-&&-delayed rectifier potassium channel activity-%%-GO:0005242-&&-inward rectifier potassium channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0042803-&&-protein homodimerization activity-%%-GO:1902282-&&-voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization-%%-GO:0015459-&&-potassium channel regulator activity	G:9606:KCNE2			KEGG-&-1&-hsa04971-&&-Gastric acid secretion	KCNE2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNE2	0.29062686	0	2	5	FALSE	KCNE2	KCNE2	41	0	2	0	0.59319363	FALSE	0	KCNE2	90	0.51282051
789745	taxon:9606	2.84023948	2.00E-08	174778	1902	uronyl 2-sulfotransferase	gene	biological_process-&-1&-GO:0006477-&&-protein sulfation-%%-GO:0030010-&&-establishment of cell polarity-%%-GO:0030208-&&-dermatan sulfate biosynthetic process-%%-GO:0050770-&&-regulation of axonogenesis|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0008146-&&-sulfotransferase activity	G:9606:UST			KEGG-&-1&-hsa00532-&&-Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate	UST	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UST	0.35208299	0	2	4	FALSE	UST	UST	750.5	0	2	0	0.69329342	FALSE	0	UST	376	0.57039574
789858	taxon:9606	3.09941705	1.20E-07	174496	1902	adipogenesis regulatory factor	gene	biological_process-&-1&-GO:0045600-&&-positive regulation of fat cell differentiation-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0072719-&&-cellular response to cisplatin-%%-GO:2001023-&&-regulation of response to drug-%%-GO:0030154-&&-cell differentiation-%%-GO:0071478-&&-cellular response to radiation-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:ADIRF				ADIRF	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADIRF	0.32264132	0	2	5	FALSE	ADIRF	ADIRF	172.5	0	2	0	0.65009716	FALSE	0	ADIRF	268	0.53761755
790096	taxon:9606	2.84717189	0	173882	1902	acyl-CoA synthetase bubblegum family member 1	gene	biological_process-&-1&-GO:0001676-&&-long-chain fatty acid metabolic process-%%-GO:0042552-&&-myelination-%%-GO:0051384-&&-response to glucocorticoid-%%-GO:0000038-&&-very long-chain fatty acid metabolic process-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0031410-&&-cytoplasmic vesicle|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0102391-&&-decanoate--CoA ligase activity-%%-GO:0004467-&&-long-chain fatty acid-CoA ligase activity-%%-GO:0031957-&&-very long-chain fatty acid-CoA ligase activity	G:9606:ACSBG1			KEGG-&-1&-hsa00061-&&-Fatty acid biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa03320-&&-PPAR signaling pathway-%%-hsa04920-&&-Adipocytokine signaling pathway-%%-hsa01212-&&-Fatty acid metabolism-%%-hsa00071-&&-Fatty acid degradation	ACSBG1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACSBG1	0.35122572	1	2	5	FALSE	ACSBG1	ACSBG1	657.5	0	2	0	0.69213802	FALSE	0	ACSBG1	0	0.52474062
790162	taxon:9606	2.85268631	7.00E-08	173735	1902	phospholipase C eta 1	gene	biological_process-&-1&-GO:0016042-&&-lipid catabolic process-%%-GO:0048015-&&-phosphatidylinositol-mediated signaling-%%-GO:0043647-&&-inositol phosphate metabolic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004871-&&-signal transducer activity-%%-GO:0050429-&&-calcium-dependent phospholipase C activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004435-&&-phosphatidylinositol phospholipase C activity	G:9606:PLCH1			KEGG-&-1&-hsa01100-&&-Metabolic pathways-%%-hsa00562-&&-Inositol phosphate metabolism	PLCH1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLCH1	0.35054678	0	2	5	FALSE	PLCH1	PLCH1	598	0	2	0	0.69121895	FALSE	0	PLCH1	348	0.51688312
790163	taxon:9606	3.03466205	6.60E-07	173729	1902	golgin A8 family member A	gene	cellular_component-&-1&-GO:0032580-&&-Golgi cisterna membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005794-&&-Golgi apparatus	G:9606:GOLGA8A				GOLGA8A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GOLGA8A	0.32952599	0	2	5	FALSE	GOLGA8A	GOLGA8A	238.5	0	2	0	0.66088966	FALSE	0	GOLGA8A	484	0.50211416
790173	taxon:9606	3.27477548	6.30E-07	157328	1902	beclin 2	gene	biological_process-&-1&-GO:0032258-&&-CVT pathway-%%-GO:0044804-&&-nucleophagy-%%-GO:0000045-&&-autophagosome assembly-%%-GO:0008333-&&-endosome to lysosome transport-%%-GO:0006914-&&-autophagy-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0006995-&&-cellular response to nitrogen starvation-%%-GO:1990172-&&-G-protein coupled receptor catabolic process-%%-GO:0045324-&&-late endosome to vacuole transport|cellular_component-&-1&-GO:0034271-&&-phosphatidylinositol 3-kinase complex, class III, type I-%%-GO:0000407-&&-pre-autophagosomal structure-%%-GO:0031410-&&-cytoplasmic vesicle-%%-GO:0034272-&&-phosphatidylinositol 3-kinase complex, class III, type II|molecular_function-&-1&-GO:0032403-&&-protein complex binding-%%-GO:0005515-&&-protein binding	G:9606:BECN2			KEGG-&-1&-hsa04140-&&-Autophagy - animal-%%-hsa04215-&&-Apoptosis - multiple species-%%-hsa04371-&&-Apelin signaling pathway-%%-hsa04137-&&-Mitophagy - animal-%%-hsa05167-&&-Kaposi sarcoma-associated herpesvirus infection-%%-hsa04136-&&-Autophagy - other	BECN2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BECN2	0.30536445	0	2	5	FALSE	BECN2	BECN2	75.5	0	2	0	0.62087075	FALSE	0	BECN2	336	0.5
790333	taxon:9606	2.96785883	8.20E-07	173296	1902	chromosome 20 open reading frame 194	gene		G:9606:C20orf194				C20orf194	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C20orf194	0.33694325	0	2	5	FALSE	C20orf194	C20orf194	327.5	0	2	0	0.67202353	FALSE	0	C20orf194	648	0.50308166
790409	taxon:9606	2.90121317	1.00E-06	156706	1902	ataxin 7 like 3B	gene		G:9606:ATXN7L3B				ATXN7L3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATXN7L3B	0.34468339	0	2	5	FALSE	ATXN7L3B	ATXN7L3B	485.5	0	2	0	0.68313114	FALSE	0	ATXN7L3B	1240	0.50259336
790435	taxon:9606	3.40318261	0	140225	1902	RNA polymerase II transcription factor SIII subunit A3-like	gene		G:9606:LOC101930165				LOC101930165	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC101930165	0.29384259	1	2	5	FALSE	LOC101930165	LOC101930165	88	0	2	0	0.59946957	FALSE	0	LOC101930165	0	0.70967742
790463	taxon:9606	2.96139909	0	156397	1902	endothelial cell surface expressed chemotaxis and apoptosis regulator	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis-%%-GO:2000353-&&-positive regulation of endothelial cell apoptotic process-%%-GO:0006915-&&-apoptotic process-%%-GO:1901800-&&-positive regulation of proteasomal protein catabolic process-%%-GO:0016525-&&-negative regulation of angiogenesis-%%-GO:0001525-&&-angiogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol	G:9606:ECSCR				ECSCR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ECSCR	0.33767823	1	2	5	FALSE	ECSCR	ECSCR	364.5	0	2	0	0.67310015	FALSE	0	ECSCR	0	0.51338028
790596	taxon:9606	3.87064755	0	172009	1902	C3 and PZP like, alpha-2-macroglobulin domain containing 8	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:CPAMD8				CPAMD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPAMD8	0.2583547	1	2	5	FALSE	CPAMD8	CPAMD8	23.5	0	2	0	0.52155874	FALSE	0	CPAMD8	0	0.53409091
790782	taxon:9606	2.88782102	3.70E-07	171226	1902	cell cycle exit and neuronal differentiation 1	gene	biological_process-&-1&-GO:0021941-&&-negative regulation of cerebellar granule cell precursor proliferation-%%-GO:0021933-&&-radial glia guided migration of cerebellar granule cell-%%-GO:0021702-&&-cerebellar Purkinje cell differentiation-%%-GO:0007628-&&-adult walking behavior-%%-GO:0021686-&&-cerebellar granular layer maturation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane	G:9606:CEND1				CEND1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CEND1	0.34628185	0	2	5	FALSE	CEND1	CEND1	520	0	2	0	0.68536316	FALSE	0	CEND1	1436	0.51082677
790786	taxon:9606	2.91854419	0	171204	1902	long intergenic non-protein coding RNA 312	gene		G:9606:LINC00312				LINC00312	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LINC00312	0.34263658	1	2	5	FALSE	LINC00312	LINC00312	458	0	2	0	0.68024263	FALSE	0	LINC00312	0	0.53070684
790788	taxon:9606	2.84496613	0	171196	1902	peptidyl arginine deiminase 1	gene	biological_process-&-1&-GO:0006325-&&-chromatin organization-%%-GO:0036414-&&-histone citrullination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005737-&&-cytoplasm-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004668-&&-protein-arginine deiminase activity-%%-GO:0005509-&&-calcium ion binding	G:9606:PADI1				PADI1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PADI1	0.35149803	1	2	5	FALSE	PADI1	PADI1	680	0	2	0	0.69250565	FALSE	0	PADI1	0	0.54269753
790801	taxon:9606	3.40318261	0	138399	1902	RNA polymerase II transcription factor SIII subunit A3-like	gene		G:9606:LOC105369241				LOC105369241	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LOC105369241	0.29384259	1	2	5	FALSE	LOC105369241	LOC105369241	88	0	2	0	0.59946957	FALSE	0	LOC105369241	0	0.70967742
790806	taxon:9606	3.40853947	5.30E-07	171145	1902	potassium voltage-gated channel interacting protein 1	gene	biological_process-&-1&-GO:0065009-&&-regulation of molecular function-%%-GO:1901379-&&-regulation of potassium ion transmembrane transport-%%-GO:0061337-&&-cardiac conduction-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0030425-&&-dendrite-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005267-&&-potassium channel activity-%%-GO:0005244-&&-voltage-gated ion channel activity-%%-GO:0005515-&&-protein binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0015459-&&-potassium channel regulator activity	G:9606:KCNIP1				KCNIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNIP1	0.29338079	0	2	5	FALSE	KCNIP1	KCNIP1	56.5	0	2	0	0.59857676	FALSE	0	KCNIP1	154	0.5
790911	taxon:9606	3.23633213	3.30E-07	170717	1902	5'-nucleotidase domain containing 3	gene	biological_process-&-1&-GO:0016311-&&-dephosphorylation|cellular_component-&-1&-GO:0043235-&&-receptor complex|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0008253-&&-5'-nucleotidase activity	G:9606:NT5DC3				NT5DC3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NT5DC3	0.30899177	0	2	5	FALSE	NT5DC3	NT5DC3	104.5	0	2	0	0.62727798	FALSE	0	NT5DC3	498	0.50242718
790946	taxon:9606	3.21947377	7.50E-07	170637	1902	G protein-coupled receptor class C group 5 member B	gene	biological_process-&-1&-GO:0010976-&&-positive regulation of neuron projection development-%%-GO:0050729-&&-positive regulation of inflammatory response-%%-GO:0032147-&&-activation of protein kinase activity-%%-GO:0043123-&&-positive regulation of I-kappaB kinase/NF-kappaB signaling-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0060907-&&-positive regulation of macrophage cytokine production-%%-GO:0090263-&&-positive regulation of canonical Wnt signaling pathway-%%-GO:0045666-&&-positive regulation of neuron differentiation-%%-GO:0042593-&&-glucose homeostasis-%%-GO:0061098-&&-positive regulation of protein tyrosine kinase activity-%%-GO:0007626-&&-locomotory behavior|cellular_component-&-1&-GO:0045121-&&-membrane raft-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0009986-&&-cell surface-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0030659-&&-cytoplasmic vesicle membrane-%%-GO:0005829-&&-cytosol-%%-GO:0005730-&&-nucleolus|molecular_function-&-1&-GO:0019901-&&-protein kinase binding-%%-GO:0030295-&&-protein kinase activator activity-%%-GO:0001664-&&-G-protein coupled receptor binding-%%-GO:0004930-&&-G-protein coupled receptor activity	G:9606:GPRC5B				GPRC5B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPRC5B	0.31060977	0	2	5	FALSE	GPRC5B	GPRC5B	142	0	2	0	0.63008771	FALSE	0	GPRC5B	698	0.50357143
791019	taxon:9606	3.08476446	4.00E-08	153973	1902	perilipin 4	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005811-&&-lipid particle-%%-GO:0005829-&&-cytosol-%%-GO:0043231-&&-intracellular membrane-bounded organelle	G:9606:PLIN4			KEGG-&-1&-hsa03320-&&-PPAR signaling pathway	PLIN4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLIN4	0.32417386	0	2	5	FALSE	PLIN4	PLIN4	151	0	2	0	0.65253926	FALSE	0	PLIN4	74	0.50675676
791024	taxon:9606	2.88955412	1.10E-07	170328	1902	torsin family 4 member A	gene	biological_process-&-1&-GO:0002576-&&-platelet degranulation|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031093-&&-platelet alpha granule lumen|molecular_function-&-1&-GO:0005524-&&-ATP binding	G:9606:TOR4A				TOR4A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TOR4A	0.34607415	0	2	5	FALSE	TOR4A	TOR4A	536	0	2	0	0.68507431	FALSE	0	TOR4A	558	0.51841085
791053	taxon:9606	2.9651804	4.00E-08	170212	1902	kinesin family member 27	gene	biological_process-&-1&-GO:0060271-&&-cilium assembly-%%-GO:0003351-&&-epithelial cilium movement-%%-GO:0007018-&&-microtubule-based movement-%%-GO:0021591-&&-ventricular system development|cellular_component-&-1&-GO:0005871-&&-kinesin complex-%%-GO:0005929-&&-cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005874-&&-microtubule|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0008574-&&-ATP-dependent microtubule motor activity, plus-end-directed-%%-GO:0008017-&&-microtubule binding	G:9606:KIF27				KIF27	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KIF27	0.33724761	0	2	5	FALSE	KIF27	KIF27	349	0	2	0	0.67246993	FALSE	0	KIF27	230	0.51708767
791066	taxon:9606	2.8342524	0	170162	1902	transmembrane and coiled-coil domains 3	gene	biological_process-&-1&-GO:1902600-&&-hydrogen ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0015299-&&-solute:proton antiporter activity-%%-GO:0022890-&&-inorganic cation transmembrane transporter activity	G:9606:TMCO3				TMCO3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMCO3	0.35282673	1	2	5	FALSE	TMCO3	TMCO3	671.5	0	2	0	0.69429127	FALSE	0	TMCO3	0	0.52749411
791116	taxon:9606	2.90278872	4.60E-07	169999	1902	serine/threonine/tyrosine kinase 1	gene	biological_process-&-1&-GO:0007155-&&-cell adhesion-%%-GO:0030154-&&-cell differentiation-%%-GO:0043304-&&-regulation of mast cell degranulation-%%-GO:0016477-&&-cell migration-%%-GO:0038083-&&-peptidyl-tyrosine autophosphorylation-%%-GO:0045087-&&-innate immune response-%%-GO:0006935-&&-chemotaxis-%%-GO:0007173-&&-epidermal growth factor receptor signaling pathway-%%-GO:0042127-&&-regulation of cell proliferation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004715-&&-non-membrane spanning protein tyrosine kinase activity-%%-GO:0005102-&&-receptor binding-%%-GO:0005515-&&-protein binding	G:9606:STYK1				STYK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STYK1	0.34449631	0	2	5	FALSE	STYK1	STYK1	473	0	2	0	0.68286855	FALSE	0	STYK1	2382	0.5273743
791204	taxon:9606	2.81959981	8.10E-07	169735	1902	spermatogenesis associated 7	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:1903621-&&-protein localization to photoreceptor connecting cilium-%%-GO:1903546-&&-protein localization to photoreceptor outer segment-%%-GO:0050896-&&-response to stimulus-%%-GO:0045494-&&-photoreceptor cell maintenance|cellular_component-&-1&-GO:0036064-&&-ciliary basal body-%%-GO:0005930-&&-axoneme-%%-GO:0005829-&&-cytosol-%%-GO:0032391-&&-photoreceptor connecting cilium-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005739-&&-mitochondrion-%%-GO:0015630-&&-microtubule cytoskeleton|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:SPATA7				SPATA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPATA7	0.35466026	0	2	5	FALSE	SPATA7	SPATA7	709	0	2	0	0.69673336	FALSE	0	SPATA7	5356	0.52600297
791235	taxon:9606	3.43374823	2.70E-07	169574	1902	zinc finger protein 253	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0045892-&&-negative regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0008270-&&-zinc ion binding	G:9606:ZNF253				ZNF253	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF253	0.29122694	0	2	5	FALSE	ZNF253	ZNF253	45	0	2	0	0.5943753	FALSE	0	ZNF253	146	0.5
791245	taxon:9606	3.04301245	3.10E-07	169547	1902	ankyrin repeat domain 7	gene	biological_process-&-1&-GO:0008584-&&-male gonad development	G:9606:ANKRD7				ANKRD7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD7	0.32862173	0	2	5	FALSE	ANKRD7	ANKRD7	229	0	2	0	0.65949793	FALSE	0	ANKRD7	384	0.50892857
791334	taxon:9606	2.96218686	3.60E-07	169108	1902	calcium/calmodulin dependent protein kinase IG	gene	biological_process-&-1&-GO:0018107-&&-peptidyl-threonine phosphorylation-%%-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular-%%-GO:0043005-&&-neuron projection-%%-GO:0005954-&&-calcium- and calmodulin-dependent protein kinase complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005516-&&-calmodulin binding-%%-GO:0004683-&&-calmodulin-dependent protein kinase activity	G:9606:CAMK1G			KEGG-&-1&-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa05214-&&-Glioma-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04921-&&-Oxytocin signaling pathway	CAMK1G	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CAMK1G	0.33758843	0	2	5	FALSE	CAMK1G	CAMK1G	340.5	0	2	0	0.67296886	FALSE	0	CAMK1G	596	0.50747384
791394	taxon:9606	3.12415314	1.08E-04	168817	1902	interleukin 22 receptor subunit alpha 1	gene	biological_process-&-1&-GO:0050829-&&-defense response to Gram-negative bacterium-%%-GO:0008150-&&-biological_process-%%-GO:0019221-&&-cytokine-mediated signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0042015-&&-interleukin-20 binding-%%-GO:0005515-&&-protein binding-%%-GO:0004904-&&-interferon receptor activity	G:9606:IL22RA1			KEGG-&-1&-hsa04630-&&-JAK-STAT signaling pathway-%%-hsa04060-&&-Cytokine-cytokine receptor interaction	IL22RA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IL22RA1	0.32008674	0	2	5	FALSE	IL22RA1	IL22RA1	136.5	0	2	0	0.64597448	FALSE	0	IL22RA1	56464	0.5
791445	taxon:9606	2.91901686	1.19E-06	168611	1902	dual specificity phosphatase 26	gene	biological_process-&-1&-GO:1902310-&&-positive regulation of peptidyl-serine dephosphorylation-%%-GO:0044387-&&-negative regulation of protein kinase activity by regulation of protein phosphorylation-%%-GO:0070373-&&-negative regulation of ERK1 and ERK2 cascade-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0045785-&&-positive regulation of cell adhesion|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005739-&&-mitochondrion-%%-GO:0005794-&&-Golgi apparatus-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0004647-&&-phosphoserine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0002039-&&-p53 binding-%%-GO:0004721-&&-phosphoprotein phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0001102-&&-RNA polymerase II activating transcription factor binding	G:9606:DUSP26				DUSP26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP26	0.3425811	0	2	5	FALSE	DUSP26	DUSP26	478.5	0	2	0	0.68016386	FALSE	0	DUSP26	1400	0.50316122
791485	taxon:9606	2.90515204	5.30E-07	168444	1902	neuronal PAS domain protein 3	gene	biological_process-&-1&-GO:0032502-&&-developmental process-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046983-&&-protein dimerization activity	G:9606:NPAS3				NPAS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NPAS3	0.34421606	0	2	4	FALSE	NPAS3	NPAS3	493.5	0	2	0	0.68247466	FALSE	0	NPAS3	978	0.50461066
791491	taxon:9606	3.00693241	1.80E-07	168404	1902	xylosyltransferase 1	gene	biological_process-&-1&-GO:0015012-&&-heparan sulfate proteoglycan biosynthetic process-%%-GO:0030203-&&-glycosaminoglycan metabolic process-%%-GO:0030206-&&-chondroitin sulfate biosynthetic process-%%-GO:0006024-&&-glycosaminoglycan biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005576-&&-extracellular region-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0030158-&&-protein xylosyltransferase activity-%%-GO:0008375-&&-acetylglucosaminyltransferase activity	G:9606:XYLT1			KEGG-&-1&-hsa00532-&&-Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate-%%-hsa01100-&&-Metabolic pathways-%%-hsa00534-&&-Glycosaminoglycan biosynthesis - heparan sulfate / heparin	XYLT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-XYLT1	0.33256484	0	2	4	FALSE	XYLT1	XYLT1	324	0	2	0	0.66551127	FALSE	0	XYLT1	416	0.50786164
791511	taxon:9606	3.21947377	4.90E-07	168343	1902	matrix metallopeptidase 25	gene	biological_process-&-1&-GO:0006508-&&-proteolysis-%%-GO:0060022-&&-hard palate development-%%-GO:0006954-&&-inflammatory response-%%-GO:0043312-&&-neutrophil degranulation|cellular_component-&-1&-GO:0016020-&&-membrane-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0035579-&&-specific granule membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005578-&&-proteinaceous extracellular matrix|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0004222-&&-metalloendopeptidase activity	G:9606:MMP25			KEGG-&-1&-hsa04928-&&-Parathyroid hormone synthesis, secretion and action	MMP25	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MMP25	0.31060977	0	2	5	FALSE	MMP25	MMP25	63.5	0	2	0	0.63008771	FALSE	0	MMP25	314	0.5
791515	taxon:9606	3.22908461	4.00E-07	168326	1902	transmembrane protein 168	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030133-&&-transport vesicle	G:9606:TMEM168				TMEM168	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM168	0.30968529	0	2	5	FALSE	TMEM168	TMEM168	96	0	2	0	0.6284859	FALSE	0	TMEM168	568	0.5026455
791542	taxon:9606	3.05025997	3.60E-07	168129	1902	high mobility group nucleosome binding domain 5	gene	biological_process-&-1&-GO:0010628-&&-positive regulation of gene expression-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0016569-&&-covalent chromatin modification-%%-GO:0071157-&&-negative regulation of cell cycle arrest-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0000785-&&-chromatin-%%-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003682-&&-chromatin binding-%%-GO:0003723-&&-RNA binding-%%-GO:0031492-&&-nucleosomal DNA binding	G:9606:HMGN5				HMGN5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HMGN5	0.32784091	0	2	5	FALSE	HMGN5	HMGN5	223	0	2	0	0.65829001	FALSE	0	HMGN5	400	0.50917431
791550	taxon:9606	3.14305971	6.00E-07	168061	1902	solute carrier family 52 member 2	gene	biological_process-&-1&-GO:0006771-&&-riboflavin metabolic process-%%-GO:0046718-&&-viral entry into host cell-%%-GO:0032218-&&-riboflavin transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0001618-&&-virus receptor activity-%%-GO:0032217-&&-riboflavin transporter activity-%%-GO:0005515-&&-protein binding	G:9606:SLC52A2				SLC52A2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC52A2	0.31816131	0	2	5	FALSE	SLC52A2	SLC52A2	160	0	2	0	0.64282338	FALSE	0	SLC52A2	366	0.5
791583	taxon:9606	2.8359855	0	167925	1902	alpha kinase 1	gene	biological_process-&-1&-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:ALPK1				ALPK1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALPK1	0.35261111	1	2	4	FALSE	ALPK1	ALPK1	712.5	0	2	0	0.69400242	FALSE	0	ALPK1	0	0.54389313
791684	taxon:9606	3.41878053	1.22E-06	167445	1902	solute carrier family 35 member G2	gene	cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005794-&&-Golgi apparatus	G:9606:SLC35G2				SLC35G2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC35G2	0.29250196	0	2	5	FALSE	SLC35G2	SLC35G2	50.5	0	2	0	0.59686991	FALSE	0	SLC35G2	340	0.5
791780	taxon:9606	3.01748858	0	166909	1902	IQ motif containing G	gene	biological_process-&-1&-GO:0007288-&&-sperm axoneme assembly-%%-GO:0007286-&&-spermatid development|cellular_component-&-1&-GO:0031514-&&-motile cilium-%%-GO:0005737-&&-cytoplasm-%%-GO:0036126-&&-sperm flagellum-%%-GO:0070062-&&-extracellular exosome-%%-GO:0002177-&&-manchette|molecular_function-&-1&-GO:0030544-&&-Hsp70 protein binding-%%-GO:0005516-&&-calmodulin binding	G:9606:IQCG				IQCG	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-IQCG	0.33140142	1	2	5	FALSE	IQCG	IQCG	262.5	0	2	0	0.6637519	FALSE	0	IQCG	0	0.51571709
791786	taxon:9606	2.76839452	7.00E-08	166876	1902	alkB homolog 7	gene	biological_process-&-1&-GO:0010883-&&-regulation of lipid storage-%%-GO:1902445-&&-regulation of mitochondrial membrane permeability involved in programmed necrotic cell death-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006974-&&-cellular response to DNA damage stimulus-%%-GO:0006631-&&-fatty acid metabolic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0051213-&&-dioxygenase activity	G:9606:ALKBH7				ALKBH7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ALKBH7	0.36122019	0	2	5	FALSE	ALKBH7	ALKBH7	882	0	2	0	0.70526758	FALSE	0	ALKBH7	724	0.54517327
791823	taxon:9606	2.91035135	9.70E-07	166685	1902	mitochondria localized glutamic acid rich protein	gene	biological_process-&-1&-GO:0010822-&&-positive regulation of mitochondrion organization-%%-GO:0008089-&&-anterograde axonal transport-%%-GO:0019896-&&-axonal transport of mitochondrion-%%-GO:0071456-&&-cellular response to hypoxia-%%-GO:0010821-&&-regulation of mitochondrion organization-%%-GO:0008090-&&-retrograde axonal transport-%%-GO:0071383-&&-cellular response to steroid hormone stimulus-%%-GO:0006626-&&-protein targeting to mitochondrion-%%-GO:0097211-&&-cellular response to gonadotropin-releasing hormone|cellular_component-&-1&-GO:1904115-&&-axon cytoplasm-%%-GO:0031307-&&-integral component of mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:MGARP				MGARP	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MGARP	0.34360113	0	2	5	FALSE	MGARP	MGARP	476	0	2	0	0.68160811	FALSE	0	MGARP	1298	0.50531915
791827	taxon:9606	3.14321727	1.40E-07	166660	1902	N(alpha)-acetyltransferase 11, NatA catalytic subunit	gene	biological_process-&-1&-GO:0018002-&&-N-terminal peptidyl-glutamic acid acetylation-%%-GO:0006475-&&-internal protein amino acid acetylation-%%-GO:0017198-&&-N-terminal peptidyl-serine acetylation-%%-GO:0006474-&&-N-terminal protein amino acid acetylation|cellular_component-&-1&-GO:0022626-&&-cytosolic ribosome-%%-GO:0005634-&&-nucleus-%%-GO:0031415-&&-NatA complex|molecular_function-&-1&-GO:0004596-&&-peptide alpha-N-acetyltransferase activity-%%-GO:1990190-&&-peptide-glutamate-N-acetyltransferase activity-%%-GO:1990189-&&-peptide-serine-N-acetyltransferase activity-%%-GO:0005515-&&-protein binding	G:9606:NAA11				NAA11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NAA11	0.31814536	0	2	5	FALSE	NAA11	NAA11	104.5	0	2	0	0.64279712	FALSE	0	NAA11	174	0.50735294
791843	taxon:9606	2.89302032	4.20E-07	166600	1902	apoptosis inducing factor, mitochondria associated 2	gene	biological_process-&-1&-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0008637-&&-apoptotic mitochondrial changes-%%-GO:0042981-&&-regulation of apoptotic process-%%-GO:0055114-&&-oxidation-reduction process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005615-&&-extracellular space-%%-GO:0005811-&&-lipid particle-%%-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol-%%-GO:0005741-&&-mitochondrial outer membrane-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0004174-&&-electron-transferring-flavoprotein dehydrogenase activity-%%-GO:0050660-&&-flavin adenine dinucleotide binding	G:9606:AIFM2			KEGG-&-1&-hsa04115-&&-p53 signaling pathway	AIFM2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AIFM2	0.34565951	0	2	4	FALSE	AIFM2	AIFM2	521	0	2	0	0.68449661	FALSE	0	AIFM2	1392	0.50682261
791946	taxon:9606	3.08570978	3.20E-07	166440	1902	regulator of G-protein signaling 8	gene	biological_process-&-1&-GO:0007213-&&-G-protein coupled acetylcholine receptor signaling pathway-%%-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity-%%-GO:0060159-&&-regulation of dopamine receptor signaling pathway|cellular_component-&-1&-GO:0043204-&&-perikaryon-%%-GO:0031234-&&-extrinsic component of cytoplasmic side of plasma membrane-%%-GO:0032809-&&-neuronal cell body membrane-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0030425-&&-dendrite-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity-%%-GO:0005515-&&-protein binding	G:9606:RGS8				RGS8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS8	0.32407455	0	2	5	FALSE	RGS8	RGS8	211	0	2	0	0.6523817	FALSE	0	RGS8	574	0.50119332
792003	taxon:9606	3.23018749	6.00E-07	166361	1902	zinc finger protein 804A	gene	molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:ZNF804A				ZNF804A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF804A	0.30957955	0	2	5	FALSE	ZNF804A	ZNF804A	130	0	2	0	0.62830208	FALSE	0	ZNF804A	1238	0.50390625
792089	taxon:9606	3.10776745	1.20E-07	166252	1902	serpin family B member 11 (gene/pseudogene)	gene	biological_process-&-1&-GO:0010951-&&-negative regulation of endopeptidase activity|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004867-&&-serine-type endopeptidase inhibitor activity	G:9606:SERPINB11				SERPINB11	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SERPINB11	0.3217744	0	2	5	FALSE	SERPINB11	SERPINB11	112	0	2	0	0.64870543	FALSE	0	SERPINB11	148	0.50454545
792139	taxon:9606	3.02174256	2.40E-07	166147	1902	chromosome 15 open reading frame 57	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C15orf57				C15orf57	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C15orf57	0.33093488	0	2	5	FALSE	C15orf57	C15orf57	272	0	2	0	0.66304291	FALSE	0	C15orf57	776	0.52015355
792169	taxon:9606	3.12824957	0	182487	1902	aquaporin 3 (Gill blood group)	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0045616-&&-regulation of keratinocyte differentiation-%%-GO:0007588-&&-excretion-%%-GO:0070295-&&-renal water absorption-%%-GO:0032526-&&-response to retinoic acid-%%-GO:0033280-&&-response to vitamin D-%%-GO:0003091-&&-renal water homeostasis-%%-GO:0006833-&&-water transport-%%-GO:0015793-&&-glycerol transport-%%-GO:0042476-&&-odontogenesis-%%-GO:0051592-&&-response to calcium ion-%%-GO:0015840-&&-urea transport-%%-GO:0002684-&&-positive regulation of immune system process|cellular_component-&-1&-GO:0005911-&&-cell-cell junction-%%-GO:0005886-&&-plasma membrane-%%-GO:0016323-&&-basolateral plasma membrane-%%-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0015250-&&-water channel activity-%%-GO:0005215-&&-transporter activity-%%-GO:0015254-&&-glycerol channel activity	G:9606:AQP3			KEGG-&-1&-hsa04962-&&-Vasopressin-regulated water reabsorption	AQP3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AQP3	0.31966759	1	2	5	FALSE	AQP3	AQP3	119.5	0	2	0	0.64529174	FALSE	0	AQP3	0	0.52183406
792209	taxon:9606	2.84307547	0	166024	1902	intestine specific homeobox	gene	biological_process-&-1&-GO:1904479-&&-negative regulation of intestinal absorption-%%-GO:1901738-&&-regulation of vitamin A metabolic process-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0001227-&&-transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:ISX				ISX	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ISX	0.35173178	1	2	4	FALSE	ISX	ISX	664	0	2	0	0.69282076	FALSE	0	ISX	0	0.54650206
792236	taxon:9606	2.90467938	8.57E-06	165984	1902	dermokine	gene	biological_process-&-1&-GO:1903575-&&-cornified envelope assembly|cellular_component-&-1&-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:DMKN				DMKN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DMKN	0.34427208	0	2	5	FALSE	DMKN	DMKN	506	0	2	0	0.68255344	FALSE	0	DMKN	4532	0.50049554
792411	taxon:9606	3.03434694	2.70E-07	165683	1902	ArfGAP with GTPase domain, ankyrin repeat and PH domain 4	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGAP4				AGAP4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGAP4	0.32956021	0	2	5	FALSE	AGAP4	AGAP4	246.5	0	2	0	0.66094218	FALSE	0	AGAP4	398	0.5093361
792415	taxon:9606	3.64786513	1.50E-07	165673	1902	galactosidase beta 1 like 3	gene	biological_process-&-1&-GO:0005975-&&-carbohydrate metabolic process|cellular_component-&-1&-GO:0005773-&&-vacuole|molecular_function-&-1&-GO:0004565-&&-beta-galactosidase activity	G:9606:GLB1L3				GLB1L3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GLB1L3	0.27413294	0	2	5	FALSE	GLB1L3	GLB1L3	15	0	2	0	0.55868914	FALSE	0	GLB1L3	64	0.5
792462	taxon:9606	3.07925004	6.00E-08	181976	1902	arginine vasopressin receptor 1A	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0032849-&&-positive regulation of cellular pH reduction-%%-GO:0051412-&&-response to corticosterone-%%-GO:0001992-&&-regulation of systemic arterial blood pressure by vasopressin-%%-GO:0042631-&&-cellular response to water deprivation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0002125-&&-maternal aggressive behavior-%%-GO:0042713-&&-sperm ejaculation-%%-GO:0035815-&&-positive regulation of renal sodium excretion-%%-GO:0010460-&&-positive regulation of heart rate-%%-GO:0021537-&&-telencephalon development-%%-GO:0051970-&&-negative regulation of transmission of nerve impulse-%%-GO:0031394-&&-positive regulation of prostaglandin biosynthetic process-%%-GO:0014049-&&-positive regulation of glutamate secretion-%%-GO:0043084-&&-penile erection-%%-GO:0007621-&&-negative regulation of female receptivity-%%-GO:0019722-&&-calcium-mediated signaling-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0014902-&&-myotube differentiation-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0035176-&&-social behavior-%%-GO:0006091-&&-generation of precursor metabolites and energy-%%-GO:0003084-&&-positive regulation of systemic arterial blood pressure-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0008015-&&-blood circulation-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1901652-&&-response to peptide-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0007625-&&-grooming behavior-%%-GO:0042711-&&-maternal behavior|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0042277-&&-peptide binding-%%-GO:0005515-&&-protein binding-%%-GO:0005080-&&-protein kinase C binding-%%-GO:0017046-&&-peptide hormone binding-%%-GO:0005000-&&-vasopressin receptor activity-%%-GO:0031894-&&-V1A vasopressin receptor binding	G:9606:AVPR1A			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	AVPR1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AVPR1A	0.3247544	0	2	5	FALSE	AVPR1A	AVPR1A	196	0	2	0	0.65345833	FALSE	0	AVPR1A	164	0.51181102
792467	taxon:9606	3.07925004	6.00E-08	181975	1902	arginine vasopressin receptor 1B	gene	biological_process-&-1&-GO:0007204-&&-positive regulation of cytosolic calcium ion concentration-%%-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0001992-&&-regulation of systemic arterial blood pressure by vasopressin-%%-GO:0007202-&&-activation of phospholipase C activity-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0045907-&&-positive regulation of vasoconstriction-%%-GO:1901652-&&-response to peptide|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005768-&&-endosome|molecular_function-&-1&-GO:0005080-&&-protein kinase C binding-%%-GO:0042277-&&-peptide binding-%%-GO:0005000-&&-vasopressin receptor activity	G:9606:AVPR1B			KEGG-&-1&-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa04020-&&-Calcium signaling pathway-%%-hsa04072-&&-Phospholipase D signaling pathway-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	AVPR1B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AVPR1B	0.3247544	0	2	5	FALSE	AVPR1B	AVPR1B	196	0	2	0	0.65345833	FALSE	0	AVPR1B	164	0.51181102
792598	taxon:9606	3.04569088	0	181736	1902	dual specificity phosphatase 5	gene	biological_process-&-1&-GO:0035970-&&-peptidyl-threonine dephosphorylation-%%-GO:0001706-&&-endoderm formation-%%-GO:0016311-&&-dephosphorylation-%%-GO:0000165-&&-MAPK cascade-%%-GO:0000187-&&-activation of MAPK activity-%%-GO:0000188-&&-inactivation of MAPK activity-%%-GO:0006470-&&-protein dephosphorylation-%%-GO:0035335-&&-peptidyl-tyrosine dephosphorylation|cellular_component-&-1&-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0017017-&&-MAP kinase tyrosine/serine/threonine phosphatase activity-%%-GO:0004725-&&-protein tyrosine phosphatase activity-%%-GO:0008138-&&-protein tyrosine/serine/threonine phosphatase activity-%%-GO:0005515-&&-protein binding-%%-GO:0016791-&&-phosphatase activity	G:9606:DUSP5			KEGG-&-1&-hsa04010-&&-MAPK signaling pathway	DUSP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DUSP5	0.32833273	1	2	5	FALSE	DUSP5	DUSP5	296	0	2	0	0.65905152	FALSE	0	DUSP5	0	0.68837209
792650	taxon:9606	3.2768237	5.00E-08	181637	1902	cytochrome P450 family 1 subfamily B member 1	gene	biological_process-&-1&-GO:0046466-&&-membrane lipid catabolic process-%%-GO:0032088-&&-negative regulation of NF-kappaB transcription factor activity-%%-GO:0042572-&&-retinol metabolic process-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0008210-&&-estrogen metabolic process-%%-GO:0002930-&&-trabecular meshwork development-%%-GO:0046427-&&-positive regulation of JAK-STAT cascade-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0061304-&&-retinal blood vessel morphogenesis-%%-GO:0009636-&&-response to toxic substance-%%-GO:0009404-&&-toxin metabolic process-%%-GO:0007601-&&-visual perception-%%-GO:0048514-&&-blood vessel morphogenesis-%%-GO:0030336-&&-negative regulation of cell migration-%%-GO:0033629-&&-negative regulation of cell adhesion mediated by integrin-%%-GO:0007155-&&-cell adhesion-%%-GO:0097267-&&-omega-hydroxylase P450 pathway-%%-GO:0008631-&&-intrinsic apoptotic signaling pathway in response to oxidative stress-%%-GO:0043542-&&-endothelial cell migration-%%-GO:0006809-&&-nitric oxide biosynthetic process-%%-GO:0030199-&&-collagen fibril organization-%%-GO:0043065-&&-positive regulation of apoptotic process-%%-GO:0071407-&&-cellular response to organic cyclic compound-%%-GO:2000377-&&-regulation of reactive oxygen species metabolic process-%%-GO:0042574-&&-retinal metabolic process-%%-GO:0070301-&&-cellular response to hydrogen peroxide-%%-GO:0071603-&&-endothelial cell-cell adhesion-%%-GO:0006725-&&-cellular aromatic compound metabolic process-%%-GO:0010575-&&-positive regulation of vascular endothelial growth factor production-%%-GO:0016125-&&-sterol metabolic process-%%-GO:0019369-&&-arachidonic acid metabolic process-%%-GO:0001525-&&-angiogenesis-%%-GO:0045766-&&-positive regulation of angiogenesis-%%-GO:0008285-&&-negative regulation of cell proliferation|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0005739-&&-mitochondrion-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0005506-&&-iron ion binding-%%-GO:0070330-&&-aromatase activity-%%-GO:0020037-&&-heme binding-%%-GO:0016712-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-%%-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding	G:9606:CYP1B1	CYP1B1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00380-&&-Tryptophan metabolism-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa05206-&&-MicroRNAs in cancer-%%-hsa05204-&&-Chemical carcinogenesis	CYP1B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP1B1	0.30517357	0	2	5	FALSE	CYP1B1	CYP1B1	59.5	0	2	0	0.62052938	FALSE	0	CYP1B1	58	0.50869565
792651	taxon:9606	3.52434221	0	181636	1902	cytochrome P450 family 2 subfamily A member 6	gene	biological_process-&-1&-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0046226-&&-coumarin catabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0009804-&&-coumarin metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0042738-&&-exogenous drug catabolic process|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0005881-&&-cytoplasmic microtubule|molecular_function-&-1&-GO:0008389-&&-coumarin 7-hydroxylase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0008392-&&-arachidonic acid epoxygenase activity-%%-GO:0016712-&&-oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding	G:9606:CYP2A6			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00232-&&-Caffeine metabolism-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00830-&&-Retinol metabolism	CYP2A6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP2A6	0.28374089	1	2	5	FALSE	CYP2A6	CYP2A6	26	0	2	0	0.5792763	FALSE	0	CYP2A6	0	0.59090909
792678	taxon:9606	3.09169686	3.50E-07	165188	1902	ankyrin repeat domain 26 pseudogene 1	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:ANKRD26P1				ANKRD26P1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANKRD26P1	0.32344698	0	2	5	FALSE	ANKRD26P1	ANKRD26P1	159.5	0	2	0	0.65138386	FALSE	0	ANKRD26P1	374	0.50477707
792835	taxon:9606	3.03025051	6.00E-08	181291	1902	EPH receptor A5	gene	biological_process-&-1&-GO:0061178-&&-regulation of insulin secretion involved in cellular response to glucose stimulus-%%-GO:0048013-&&-ephrin receptor signaling pathway-%%-GO:0032793-&&-positive regulation of CREB transcription factor activity-%%-GO:0021766-&&-hippocampus development-%%-GO:0032956-&&-regulation of actin cytoskeleton organization-%%-GO:0019933-&&-cAMP-mediated signaling-%%-GO:0048666-&&-neuron development-%%-GO:0007411-&&-axon guidance-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0018108-&&-peptidyl-tyrosine phosphorylation|cellular_component-&-1&-GO:0009897-&&-external side of plasma membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0043025-&&-neuronal cell body-%%-GO:0030424-&&-axon-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005791-&&-rough endoplasmic reticulum-%%-GO:0030425-&&-dendrite|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005004-&&-GPI-linked ephrin receptor activity-%%-GO:0005003-&&-ephrin receptor activity-%%-GO:0005005-&&-transmembrane-ephrin receptor activity	G:9606:EPHA5			KEGG-&-1&-hsa04360-&&-Axon guidance	EPHA5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-EPHA5	0.33000572	0	2	5	FALSE	EPHA5	EPHA5	239.5	0	2	0	0.66162491	FALSE	0	EPHA5	204	0.52074236
792917	taxon:9606	3.01165905	7.00E-08	181156	1902	gamma-aminobutyric acid type A receptor alpha2 subunit	gene	biological_process-&-1&-GO:0007214-&&-gamma-aminobutyric acid signaling pathway-%%-GO:0001505-&&-regulation of neurotransmitter levels-%%-GO:0006836-&&-neurotransmitter transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:1902476-&&-chloride transmembrane transport|cellular_component-&-1&-GO:1902711-&&-GABA-A receptor complex-%%-GO:0030285-&&-integral component of synaptic vesicle membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0034707-&&-chloride channel complex|molecular_function-&-1&-GO:0008503-&&-benzodiazepine receptor activity-%%-GO:0022851-&&-GABA-gated chloride ion channel activity-%%-GO:0004890-&&-GABA-A receptor activity	G:9606:GABRA2	GABRA2	TRUE	KEGG-&-1&-hsa05032-&&-Morphine addiction-%%-hsa04727-&&-GABAergic synapse-%%-hsa04723-&&-Retrograde endocannabinoid signaling-%%-hsa05033-&&-Nicotine addiction-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	GABRA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GABRA2	0.3320429	0	2	5	FALSE	GABRA2	GABRA2	262.5	0	2	0	0.66472349	FALSE	0	GABRA2	338	0.52721774
793063	taxon:9606	2.95840555	1.23E-06	164428	1902	myosin IIIB	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0050896-&&-response to stimulus|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0016459-&&-myosin complex|molecular_function-&-1&-GO:0003779-&&-actin binding-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0003774-&&-motor activity	G:9606:MYO3B				MYO3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-MYO3B	0.33801992	0	2	5	FALSE	MYO3B	MYO3B	346.5	0	2	0	0.67359908	FALSE	0	MYO3B	958	0.50145138
793086	taxon:9606	2.91129668	0	164381	1902	CDK2 associated cullin domain 1	gene	biological_process-&-1&-GO:0045860-&&-positive regulation of protein kinase activity-%%-GO:0042787-&&-protein ubiquitination involved in ubiquitin-dependent protein catabolic process-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0000082-&&-G1/S transition of mitotic cell cycle|cellular_component-&-1&-GO:0031461-&&-cullin-RING ubiquitin ligase complex|molecular_function-&-1&-GO:0061630-&&-ubiquitin protein ligase activity-%%-GO:0031625-&&-ubiquitin protein ligase binding-%%-GO:0019901-&&-protein kinase binding-%%-GO:0005515-&&-protein binding	G:9606:CACUL1				CACUL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CACUL1	0.34348956	1	2	5	FALSE	CACUL1	CACUL1	486	0	2	0	0.68145055	FALSE	0	CACUL1	0	0.52483801
793110	taxon:9606	3.03056562	2.90E-07	164335	1902	WD repeat domain 66	gene		G:9606:WDR66				WDR66	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-WDR66	0.32997141	0	2	5	FALSE	WDR66	WDR66	253.5	0	2	0	0.6615724	FALSE	0	WDR66	666	0.5111336
793126	taxon:9606	3.7861982	0	180683	1902	growth hormone releasing hormone	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0060124-&&-positive regulation of growth hormone secretion-%%-GO:0043568-&&-positive regulation of insulin-like growth factor receptor signaling pathway-%%-GO:0046005-&&-positive regulation of circadian sleep/wake cycle, REM sleep-%%-GO:0040018-&&-positive regulation of multicellular organism growth-%%-GO:0008284-&&-positive regulation of cell proliferation-%%-GO:0030819-&&-positive regulation of cAMP biosynthetic process-%%-GO:0007189-&&-adenylate cyclase-activating G-protein coupled receptor signaling pathway-%%-GO:0032094-&&-response to food-%%-GO:0021984-&&-adenohypophysis development-%%-GO:0030252-&&-growth hormone secretion-%%-GO:0019933-&&-cAMP-mediated signaling|cellular_component-&-1&-GO:0043195-&&-terminal bouton-%%-GO:0005615-&&-extracellular space-%%-GO:0005576-&&-extracellular region-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0016608-&&-growth hormone-releasing hormone activity-%%-GO:0031770-&&-growth hormone-releasing hormone receptor binding	G:9606:GHRH	GHRH	TRUE	KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	GHRH	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GHRH	0.26411718	1	2	5	FALSE	GHRH	GHRH	26	0	2	0	0.53563363	FALSE	0	GHRH	0	0.63414634
793157	taxon:9606	3.26169844	1.90E-07	164239	1902	CKLF like MARVEL transmembrane domain containing 4	gene	biological_process-&-1&-GO:0006935-&&-chemotaxis|cellular_component-&-1&-GO:0005615-&&-extracellular space-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005125-&&-cytokine activity	G:9606:CMTM4				CMTM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMTM4	0.30658874	0	2	5	FALSE	CMTM4	CMTM4	78.5	0	2	0	0.62305026	FALSE	0	CMTM4	298	0.50653595
793173	taxon:9606	2.85315897	0	164208	1902	dynein axonemal heavy chain 2	gene	biological_process-&-1&-GO:0007018-&&-microtubule-based movement-%%-GO:0060285-&&-cilium-dependent cell motility|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005874-&&-microtubule-%%-GO:0005858-&&-axonemal dynein complex|molecular_function-&-1&-GO:0003777-&&-microtubule motor activity-%%-GO:0005524-&&-ATP binding-%%-GO:0016887-&&-ATPase activity	G:9606:DNAH2			KEGG-&-1&-hsa05016-&&-Huntington disease	DNAH2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DNAH2	0.35048871	1	2	4	FALSE	DNAH2	DNAH2	689.5	0	2	0	0.69114017	FALSE	0	DNAH2	0	0.58680851
793189	taxon:9606	3.65385221	1.50E-07	180557	1902	hepsin	gene	biological_process-&-1&-GO:0050680-&&-negative regulation of epithelial cell proliferation-%%-GO:0097195-&&-pilomotor reflex-%%-GO:0050910-&&-detection of mechanical stimulus involved in sensory perception of sound-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0090103-&&-cochlea morphogenesis-%%-GO:0097066-&&-response to thyroid hormone-%%-GO:2000611-&&-positive regulation of thyroid hormone generation-%%-GO:0043923-&&-positive regulation by host of viral transcription-%%-GO:0010756-&&-positive regulation of plasminogen activation-%%-GO:0006508-&&-proteolysis-%%-GO:0034769-&&-basement membrane disassembly-%%-GO:0071805-&&-potassium ion transmembrane transport-%%-GO:2000347-&&-positive regulation of hepatocyte proliferation-%%-GO:0048012-&&-hepatocyte growth factor receptor signaling pathway-%%-GO:0043066-&&-negative regulation of apoptotic process-%%-GO:0010719-&&-negative regulation of epithelial to mesenchymal transition-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0031965-&&-nuclear membrane-%%-GO:0005911-&&-cell-cell junction-%%-GO:0016324-&&-apical plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0043025-&&-neuronal cell body-%%-GO:0016021-&&-integral component of membrane-%%-GO:0009986-&&-cell surface-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding-%%-GO:0070008-&&-serine-type exopeptidase activity-%%-GO:0015269-&&-calcium-activated potassium channel activity-%%-GO:0008236-&&-serine-type peptidase activity-%%-GO:0008233-&&-peptidase activity	G:9606:HPN			KEGG-&-1&-hsa05203-&&-Viral carcinogenesis	HPN	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HPN	0.27368376	0	2	5	FALSE	HPN	HPN	15.5	0	2	0	0.5576913	FALSE	0	HPN	50	0.5
793205	taxon:9606	0	0	180528	1902	hydroxysteroid 17-beta dehydrogenase 1	gene	biological_process-&-1&-GO:0008210-&&-estrogen metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006703-&&-estrogen biosynthetic process-%%-GO:0006694-&&-steroid biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0004303-&&-estradiol 17-beta-dehydrogenase activity-%%-GO:0003824-&&-catalytic activity	G:9606:HSD17B1	HSD17B1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways	HSD17B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD17B1	0	0	2	0	TRUE	HSD17B1	HSD17B1	0	0	1	0	9.22E+10	FALSE	1	HSD17B1	0	0
793233	taxon:9606	2.99117693	9.00E-08	164100	1902	NIMA related kinase 10	gene	biological_process-&-1&-GO:0043406-&&-positive regulation of MAP kinase activity-%%-GO:0070372-&&-regulation of ERK1 and ERK2 cascade-%%-GO:1902749-&&-regulation of cell cycle G2/M phase transition-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0031954-&&-positive regulation of protein autophosphorylation|cellular_component-&-1&-GO:1902911-&&-protein kinase complex|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004672-&&-protein kinase activity	G:9606:NEK10				NEK10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-NEK10	0.33431657	0	2	5	FALSE	NEK10	NEK10	302	0	2	0	0.66813718	FALSE	0	NEK10	254	0.52256944
793238	taxon:9606	3.26658264	1.63E-06	180477	1902	5-hydroxytryptamine receptor 3A	gene	biological_process-&-1&-GO:0098664-&&-G-protein coupled serotonin receptor signaling pathway-%%-GO:0071363-&&-cellular response to growth factor stimulus-%%-GO:0007210-&&-serotonin receptor signaling pathway-%%-GO:0045471-&&-response to ethanol-%%-GO:0098655-&&-cation transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport-%%-GO:0032414-&&-positive regulation of ion transmembrane transporter activity-%%-GO:0042220-&&-response to cocaine|cellular_component-&-1&-GO:1904602-&&-serotonin-activated cation-selective channel complex-%%-GO:0032154-&&-cleavage furrow-%%-GO:0005886-&&-plasma membrane-%%-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0030424-&&-axon-%%-GO:0043025-&&-neuronal cell body-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004993-&&-G-protein coupled serotonin receptor activity-%%-GO:0005515-&&-protein binding-%%-GO:0051378-&&-serotonin binding-%%-GO:0022850-&&-serotonin-gated cation-selective channel activity	G:9606:HTR3A	HTR3A	TRUE	KEGG-&-1&-hsa04726-&&-Serotonergic synapse-%%-hsa04742-&&-Taste transduction	HTR3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTR3A	0.30613032	0	2	5	FALSE	HTR3A	HTR3A	81.5	0	2	0	0.62223623	FALSE	0	HTR3A	1540	0.5
793251	taxon:9606	3.61194265	4.10E-07	164057	1902	APC down-regulated 1	gene	biological_process-&-1&-GO:0030178-&&-negative regulation of Wnt signaling pathway-%%-GO:0043615-&&-astrocyte cell migration-%%-GO:0001942-&&-hair follicle development-%%-GO:0016055-&&-Wnt signaling pathway|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0017147-&&-Wnt-protein binding	G:9606:APCDD1				APCDD1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-APCDD1	0.27685932	0	2	5	FALSE	APCDD1	APCDD1	36.5	0	2	0	0.56467622	FALSE	0	APCDD1	180	0.5
787035	taxon:9606	3.06065858	0	163804	1902	family with sequence similarity 71 member D	gene	cellular_component-&-1&-GO:0005634-&&-nucleus	G:9606:FAM71D				FAM71D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FAM71D	0.32672707	0	1	5	FALSE	FAM71D	FAM71D	413	0	1	0	0.6565569	FALSE	0	FAM71D	0	0
787070	taxon:9606	2.91302978	0	163738	1902	CKLF like MARVEL transmembrane domain containing 8	gene	biological_process-&-1&-GO:0008104-&&-protein localization-%%-GO:0006935-&&-chemotaxis-%%-GO:0001766-&&-membrane raft polarization-%%-GO:0042552-&&-myelination|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005615-&&-extracellular space-%%-GO:0005654-&&-nucleoplasm-%%-GO:0045121-&&-membrane raft-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0019911-&&-structural constituent of myelin sheath-%%-GO:0005125-&&-cytokine activity	G:9606:CMTM8				CMTM8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CMTM8	0.3432852	0	1	5	FALSE	CMTM8	CMTM8	930	0	1	0	0.6811617	FALSE	0	CMTM8	0	0
787113	taxon:9606	2.92106507	0	163653	1902	solute carrier family 2 member 12	gene	biological_process-&-1&-GO:0015992-&&-proton transport-%%-GO:0046323-&&-glucose import-%%-GO:0035428-&&-hexose transmembrane transport-%%-GO:1904659-&&-glucose transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0048471-&&-perinuclear region of cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0012505-&&-endomembrane system|molecular_function-&-1&-GO:0055056-&&-D-glucose transmembrane transporter activity-%%-GO:0005351-&&-sugar:proton symporter activity-%%-GO:0005355-&&-glucose transmembrane transporter activity	G:9606:SLC2A12				SLC2A12	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SLC2A12	0.34234088	0	1	5	FALSE	SLC2A12	SLC2A12	942	0	1	0	0.67982249	FALSE	0	SLC2A12	0	0
787260	taxon:9606	3.12494092	0	163401	1902	progestin and adipoQ receptor family member 7	gene	biological_process-&-1&-GO:0048477-&&-oogenesis-%%-GO:0048545-&&-response to steroid hormone-%%-GO:0007275-&&-multicellular organism development-%%-GO:0043401-&&-steroid hormone mediated signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0003707-&&-steroid hormone receptor activity-%%-GO:0005496-&&-steroid binding	G:9606:PAQR7				PAQR7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PAQR7	0.32000605	0	1	5	FALSE	PAQR7	PAQR7	270	0	1	0	0.64584318	FALSE	0	PAQR7	0	0
787279	taxon:9606	3.71545612	0	179754	1902	potassium voltage-gated channel modifier subfamily F member 1	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0005267-&&-potassium channel activity-%%-GO:0005249-&&-voltage-gated potassium channel activity	G:9606:KCNF1				KCNF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNF1	0.26914596	0	1	5	FALSE	KCNF1	KCNF1	25	0	1	0	0.54742398	FALSE	0	KCNF1	0	0
787292	taxon:9606	2.97274303	0	179721	1902	potassium voltage-gated channel modifier subfamily S member 3	gene	biological_process-&-1&-GO:0051260-&&-protein homooligomerization-%%-GO:0065009-&&-regulation of molecular function-%%-GO:0050796-&&-regulation of insulin secretion-%%-GO:0034765-&&-regulation of ion transmembrane transport-%%-GO:0006813-&&-potassium ion transport-%%-GO:0071805-&&-potassium ion transmembrane transport|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol-%%-GO:0008076-&&-voltage-gated potassium channel complex-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005794-&&-Golgi apparatus|molecular_function-&-1&-GO:0015459-&&-potassium channel regulator activity-%%-GO:0005251-&&-delayed rectifier potassium channel activity	G:9606:KCNS3				KCNS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCNS3	0.33638965	0	1	5	FALSE	KCNS3	KCNS3	636	0	1	0	0.6712095	FALSE	0	KCNS3	0	0
787556	taxon:9606	2.91302978	0	162801	1902	anoctamin 5	gene	biological_process-&-1&-GO:0006821-&&-chloride transport-%%-GO:1902476-&&-chloride transmembrane transport-%%-GO:0034220-&&-ion transmembrane transport|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031982-&&-vesicle-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0046983-&&-protein dimerization activity-%%-GO:0005229-&&-intracellular calcium activated chloride channel activity	G:9606:ANO5				ANO5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ANO5	0.3432852	0	1	5	FALSE	ANO5	ANO5	930	0	1	0	0.6811617	FALSE	0	ANO5	0	0
787757	taxon:9606	2.94910982	0	178835	1902	POU class 4 homeobox 2	gene	biological_process-&-1&-GO:1990791-&&-dorsal root ganglion development-%%-GO:0045596-&&-negative regulation of cell differentiation-%%-GO:1902870-&&-negative regulation of amacrine cell differentiation-%%-GO:0031290-&&-retinal ganglion cell axon guidance-%%-GO:0043068-&&-positive regulation of programmed cell death-%%-GO:0048675-&&-axon extension-%%-GO:2000679-&&-positive regulation of transcription regulatory region DNA binding-%%-GO:0050885-&&-neuromuscular process controlling balance-%%-GO:1901796-&&-regulation of signal transduction by p53 class mediator-%%-GO:0000165-&&-MAPK cascade-%%-GO:0007605-&&-sensory perception of sound-%%-GO:0051090-&&-regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0045773-&&-positive regulation of axon extension-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007283-&&-spermatogenesis-%%-GO:0030520-&&-intracellular estrogen receptor signaling pathway-%%-GO:0007411-&&-axon guidance-%%-GO:0072332-&&-intrinsic apoptotic signaling pathway by p53 class mediator-%%-GO:0045672-&&-positive regulation of osteoclast differentiation-%%-GO:0060041-&&-retina development in camera-type eye-%%-GO:0071392-&&-cellular response to estradiol stimulus-%%-GO:0090259-&&-regulation of retinal ganglion cell axon guidance-%%-GO:0006366-&&-transcription from RNA polymerase II promoter-%%-GO:0030182-&&-neuron differentiation-%%-GO:0045597-&&-positive regulation of cell differentiation-%%-GO:0000122-&&-negative regulation of transcription from RNA polymerase II promoter-%%-GO:0043433-&&-negative regulation of sequence-specific DNA binding transcription factor activity-%%-GO:0071345-&&-cellular response to cytokine stimulus|cellular_component-&-1&-GO:0016607-&&-nuclear speck-%%-GO:0005654-&&-nucleoplasm-%%-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0003713-&&-transcription coactivator activity-%%-GO:1990841-&&-promoter-specific chromatin binding-%%-GO:0000978-&&-RNA polymerase II core promoter proximal region sequence-specific DNA binding-%%-GO:0001077-&&-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-%%-GO:0003714-&&-transcription corepressor activity-%%-GO:0001078-&&-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	G:9606:POU4F2				POU4F2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-POU4F2	0.33908537	0	1	5	FALSE	POU4F2	POU4F2	759	0	1	0	0.67514836	FALSE	0	POU4F2	0	0
788433	taxon:9606	3.61005199	0	177676	1902	single-minded family bHLH transcription factor 1	gene	biological_process-&-1&-GO:0007399-&&-nervous system development-%%-GO:0001657-&&-ureteric bud development-%%-GO:0030154-&&-cell differentiation-%%-GO:0006351-&&-transcription, DNA-templated-%%-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0000981-&&-RNA polymerase II transcription factor activity, sequence-specific DNA binding-%%-GO:0046982-&&-protein heterodimerization activity-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:SIM1				SIM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SIM1	0.27700432	0	1	5	FALSE	SIM1	SIM1	38	0	1	0	0.56499133	FALSE	0	SIM1	0	0
788611	taxon:9606	3.06065858	0	160929	1902	paralemmin 3	gene	biological_process-&-1&-GO:0008063-&&-Toll signaling pathway-%%-GO:0001960-&&-negative regulation of cytokine-mediated signaling pathway-%%-GO:0032496-&&-response to lipopolysaccharide|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0005515-&&-protein binding	G:9606:PALM3				PALM3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PALM3	0.32672707	0	1	5	FALSE	PALM3	PALM3	413	0	1	0	0.6565569	FALSE	0	PALM3	0	0
788746	taxon:9606	3.06065858	0	160661	1902	late cornified envelope 3A	gene	biological_process-&-1&-GO:0030216-&&-keratinocyte differentiation-%%-GO:0031424-&&-keratinization-%%-GO:0018149-&&-peptide cross-linking|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0001533-&&-cornified envelope|molecular_function-&-1&-GO:0005198-&&-structural molecule activity	G:9606:LCE3A				LCE3A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LCE3A	0.32672707	0	1	5	FALSE	LCE3A	LCE3A	413	0	1	0	0.6565569	FALSE	0	LCE3A	0	0
788834	taxon:9606	3.17000158	0	176781	1902	UDP glucuronosyltransferase family 2 member B10	gene	biological_process-&-1&-GO:0006629-&&-lipid metabolic process|cellular_component-&-1&-GO:0043231-&&-intracellular membrane-bounded organelle-%%-GO:0016021-&&-integral component of membrane-%%-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0015020-&&-glucuronosyltransferase activity	G:9606:UGT2B10			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa00040-&&-Pentose and glucuronate interconversions-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00860-&&-Porphyrin and chlorophyll metabolism-%%-hsa00053-&&-Ascorbate and aldarate metabolism-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa00830-&&-Retinol metabolism	UGT2B10	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UGT2B10	0.31545726	0	1	5	FALSE	UGT2B10	UGT2B10	233	0	1	0	0.63833307	FALSE	0	UGT2B10	0	0
788952	taxon:9606	3.02394832	0	176543	1902	galanin receptor 3	gene	biological_process-&-1&-GO:0007631-&&-feeding behavior-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007611-&&-learning or memory-%%-GO:0007200-&&-phospholipase C-activating G-protein coupled receptor signaling pathway-%%-GO:0007194-&&-negative regulation of adenylate cyclase activity-%%-GO:0045944-&&-positive regulation of transcription from RNA polymerase II promoter-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:0007188-&&-adenylate cyclase-modulating G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0017046-&&-peptide hormone binding-%%-GO:0004966-&&-galanin receptor activity	G:9606:GALR3			KEGG-&-1&-hsa04080-&&-Neuroactive ligand-receptor interaction	GALR3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GALR3	0.33069348	0	1	4	FALSE	GALR3	GALR3	593	0	1	0	0.66267528	FALSE	0	GALR3	0	0
788973	taxon:9606	2.94910982	0	176496	1902	zinc finger protein 182	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF182				ZNF182	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF182	0.33908537	0	1	5	FALSE	ZNF182	ZNF182	759	0	1	0	0.67514836	FALSE	0	ZNF182	0	0
789021	taxon:9606	2.97274303	0	159972	1902	tripartite motif containing 73	gene	cellular_component-&-1&-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:TRIM73				TRIM73	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRIM73	0.33638965	0	1	5	FALSE	TRIM73	TRIM73	636	0	1	0	0.6712095	FALSE	0	TRIM73	0	0
789065	taxon:9606	2.97274303	0	159875	1902	potassium channel tetramerization domain containing 8	gene	biological_process-&-1&-GO:0008277-&&-regulation of G-protein coupled receptor protein signaling pathway-%%-GO:0051260-&&-protein homooligomerization|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0045211-&&-postsynaptic membrane-%%-GO:0042734-&&-presynaptic membrane-%%-GO:0043235-&&-receptor complex	G:9606:KCTD8				KCTD8	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-KCTD8	0.33638965	0	1	5	FALSE	KCTD8	KCTD8	636	0	1	0	0.6712095	FALSE	0	KCTD8	0	0
789617	taxon:9606	2.91302978	0	175051	1902	dopey family member 2	gene	biological_process-&-1&-GO:0006895-&&-Golgi to endosome transport-%%-GO:0007275-&&-multicellular organism development-%%-GO:0015031-&&-protein transport-%%-GO:0007029-&&-endoplasmic reticulum organization-%%-GO:0050890-&&-cognition|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005768-&&-endosome-%%-GO:0005802-&&-trans-Golgi network-%%-GO:0070062-&&-extracellular exosome-%%-GO:0000139-&&-Golgi membrane|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:DOPEY2				DOPEY2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DOPEY2	0.3432852	0	1	5	FALSE	DOPEY2	DOPEY2	930	0	1	0	0.6811617	FALSE	0	DOPEY2	0	0
789641	taxon:9606	3.46005987	0	158604	1902	chromosome 4 open reading frame 48	gene	cellular_component-&-1&-GO:0005576-&&-extracellular region	G:9606:C4orf48				C4orf48	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C4orf48	0.28901234	0	1	5	FALSE	C4orf48	C4orf48	94	0	1	0	0.58999002	FALSE	0	C4orf48	0	0
789657	taxon:9606	3.51126516	0	174966	1902	phosphatidylethanolamine N-methyltransferase	gene	biological_process-&-1&-GO:0008285-&&-negative regulation of cell proliferation-%%-GO:1903955-&&-positive regulation of protein targeting to mitochondrion-%%-GO:0006656-&&-phosphatidylcholine biosynthetic process-%%-GO:0006629-&&-lipid metabolic process-%%-GO:0046500-&&-S-adenosylmethionine metabolic process-%%-GO:0046498-&&-S-adenosylhomocysteine metabolic process-%%-GO:0033273-&&-response to vitamin-%%-GO:0043200-&&-response to amino acid-%%-GO:0032259-&&-methylation-%%-GO:0050747-&&-positive regulation of lipoprotein metabolic process-%%-GO:0006686-&&-sphingomyelin biosynthetic process-%%-GO:0042493-&&-response to drug-%%-GO:0045471-&&-response to ethanol-%%-GO:0008283-&&-cell proliferation|cellular_component-&-1&-GO:0031966-&&-mitochondrial membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0031526-&&-brush border membrane-%%-GO:0042383-&&-sarcolemma-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0000773-&&-phosphatidyl-N-methylethanolamine N-methyltransferase activity-%%-GO:0004608-&&-phosphatidylethanolamine N-methyltransferase activity-%%-GO:0008429-&&-phosphatidylethanolamine binding-%%-GO:0080101-&&-phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	G:9606:PEMT			KEGG-&-1&-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa01100-&&-Metabolic pathways	PEMT	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PEMT	0.28479763	0	1	5	FALSE	PEMT	PEMT	90	0	1	0	0.58145581	FALSE	0	PEMT	0	0
790060	taxon:9606	3.06065858	0	173976	1902	blood vessel epicardial substance	gene	biological_process-&-1&-GO:0042391-&&-regulation of membrane potential-%%-GO:0008360-&&-regulation of cell shape-%%-GO:0002244-&&-hematopoietic progenitor cell differentiation-%%-GO:0007507-&&-heart development-%%-GO:0001921-&&-positive regulation of receptor recycling-%%-GO:0002027-&&-regulation of heart rate-%%-GO:0048278-&&-vesicle docking-%%-GO:0002931-&&-response to ischemia-%%-GO:0007517-&&-muscle organ development-%%-GO:0007519-&&-skeletal muscle tissue development-%%-GO:0060931-&&-sinoatrial node cell development-%%-GO:0016192-&&-vesicle-mediated transport-%%-GO:0043087-&&-regulation of GTPase activity-%%-GO:0090136-&&-epithelial cell-cell adhesion-%%-GO:0060973-&&-cell migration involved in heart development-%%-GO:0034446-&&-substrate adhesion-dependent cell spreading-%%-GO:0040017-&&-positive regulation of locomotion-%%-GO:2001135-&&-regulation of endocytic recycling|cellular_component-&-1&-GO:0030054-&&-cell junction-%%-GO:0031253-&&-cell projection membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0016021-&&-integral component of membrane-%%-GO:0016328-&&-lateral plasma membrane-%%-GO:0005901-&&-caveola-%%-GO:0042383-&&-sarcolemma-%%-GO:0005923-&&-bicellular tight junction|molecular_function-&-1&-GO:0005515-&&-protein binding-%%-GO:0005198-&&-structural molecule activity-%%-GO:0030552-&&-cAMP binding	G:9606:BVES			KEGG-&-1&-hsa04530-&&-Tight junction	BVES	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BVES	0.32672707	0	1	5	FALSE	BVES	BVES	413	0	1	0	0.6565569	FALSE	0	BVES	0	0
790369	taxon:9606	3.782732	0	173206	1902	SEC14 like lipid binding 2	gene	biological_process-&-1&-GO:0006810-&&-transport-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0045540-&&-regulation of cholesterol biosynthetic process-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0016021-&&-integral component of membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0005215-&&-transporter activity-%%-GO:0005543-&&-phospholipid binding-%%-GO:0008431-&&-vitamin E binding	G:9606:SEC14L2				SEC14L2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SEC14L2	0.2643592	0	1	6	FALSE	SEC14L2	SEC14L2	33	0	1	0	0.53621133	FALSE	0	SEC14L2	0	0
790442	taxon:9606	3.06065858	0	140170	1902	chromosome 11 open reading frame 98	gene		G:9606:C11orf98				C11orf98	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C11orf98	0.32672707	0	1	5	FALSE	C11orf98	C11orf98	413	0	1	0	0.6565569	FALSE	0	C11orf98	0	0
790454	taxon:9606	3.24562786	0	172801	1902	attractin like 1	gene	biological_process-&-1&-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0030246-&&-carbohydrate binding	G:9606:ATRNL1				ATRNL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ATRNL1	0.3081068	0	1	5	FALSE	ATRNL1	ATRNL1	188	0	1	0	0.62572869	FALSE	0	ATRNL1	0	0
790491	taxon:9606	3.12210493	0	172709	1902	regulator of G-protein signaling 22	gene	biological_process-&-1&-GO:0009968-&&-negative regulation of signal transduction-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0005096-&&-GTPase activator activity	G:9606:RGS22				RGS22	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RGS22	0.32029673	0	1	5	FALSE	RGS22	RGS22	310	0	1	0	0.64631584	FALSE	0	RGS22	0	0
790515	taxon:9606	3.23869545	0	172645	1902	phospholipase A2 group IID	gene	biological_process-&-1&-GO:0036150-&&-phosphatidylserine acyl-chain remodeling-%%-GO:0036152-&&-phosphatidylethanolamine acyl-chain remodeling-%%-GO:0050482-&&-arachidonic acid secretion-%%-GO:0006954-&&-inflammatory response-%%-GO:0042130-&&-negative regulation of T cell proliferation-%%-GO:0002361-&&-CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation-%%-GO:0006654-&&-phosphatidic acid biosynthetic process-%%-GO:0036151-&&-phosphatidylcholine acyl-chain remodeling-%%-GO:0006644-&&-phospholipid metabolic process-%%-GO:0036148-&&-phosphatidylglycerol acyl-chain remodeling-%%-GO:0036149-&&-phosphatidylinositol acyl-chain remodeling-%%-GO:0016042-&&-lipid catabolic process|cellular_component-&-1&-GO:0005576-&&-extracellular region|molecular_function-&-1&-GO:0004623-&&-phospholipase A2 activity-%%-GO:0008201-&&-heparin binding-%%-GO:0005509-&&-calcium ion binding-%%-GO:0043395-&&-heparan sulfate proteoglycan binding	G:9606:PLA2G2D			KEGG-&-1&-hsa04975-&&-Fat digestion and absorption-%%-hsa00564-&&-Glycerophospholipid metabolism-%%-hsa04014-&&-Ras signaling pathway-%%-hsa04270-&&-Vascular smooth muscle contraction-%%-hsa00592-&&-alpha-Linolenic acid metabolism-%%-hsa01100-&&-Metabolic pathways-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa00565-&&-Ether lipid metabolism-%%-hsa04972-&&-Pancreatic secretion	PLA2G2D	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PLA2G2D	0.3087663	0	1	5	FALSE	PLA2G2D	PLA2G2D	257	0	1	0	0.62688409	FALSE	0	PLA2G2D	0	0
790600	taxon:9606	3.06065858	0	155521	1902	arrestin domain containing 5	gene	biological_process-&-1&-GO:0007165-&&-signal transduction	G:9606:ARRDC5				ARRDC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ARRDC5	0.32672707	0	1	5	FALSE	ARRDC5	ARRDC5	413	0	1	0	0.6565569	FALSE	0	ARRDC5	0	0
790725	taxon:9606	3.06065858	0	154993	1902	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7, pseudogene	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGAP7P				AGAP7P	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGAP7P	0.32672707	0	1	5	FALSE	AGAP7P	AGAP7P	413	0	1	0	0.6565569	FALSE	0	AGAP7P	0	0
790761	taxon:9606	3.41011501	0	154914	1902	glutathione S-transferase theta 2B (gene/pseudogene)	gene	biological_process-&-1&-GO:1901687-&&-glutathione derivative biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity	G:9606:GSTT2B			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05225-&&-Hepatocellular carcinoma-%%-hsa05204-&&-Chemical carcinogenesis	GSTT2B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTT2B	0.29324524	0	1	5	FALSE	GSTT2B	GSTT2B	52	0	1	0	0.59831416	FALSE	0	GSTT2B	0	0
790794	taxon:9606	3.06774854	0	171186	1902	thyrotropin releasing hormone degrading enzyme	gene	biological_process-&-1&-GO:0007267-&&-cell-cell signaling-%%-GO:0008217-&&-regulation of blood pressure-%%-GO:0007165-&&-signal transduction-%%-GO:0006508-&&-proteolysis-%%-GO:0043171-&&-peptide catabolic process|cellular_component-&-1&-GO:0070062-&&-extracellular exosome-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0070006-&&-metalloaminopeptidase activity-%%-GO:0004177-&&-aminopeptidase activity-%%-GO:0008270-&&-zinc ion binding-%%-GO:0042277-&&-peptide binding	G:9606:TRHDE				TRHDE	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TRHDE	0.32597196	0	1	5	FALSE	TRHDE	TRHDE	335	0	1	0	0.65537524	FALSE	0	TRHDE	0	0
790884	taxon:9606	3.06774854	0	170783	1902	zinc finger protein 691	gene	cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:ZNF691				ZNF691	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF691	0.32597196	0	1	5	FALSE	ZNF691	ZNF691	335	0	1	0	0.65537524	FALSE	0	ZNF691	0	0
790913	taxon:9606	3.06065858	0	154328	1902	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5	gene	biological_process-&-1&-GO:0043547-&&-positive regulation of GTPase activity|molecular_function-&-1&-GO:0046872-&&-metal ion binding-%%-GO:0005096-&&-GTPase activator activity	G:9606:AGAP5				AGAP5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-AGAP5	0.32672707	0	1	5	FALSE	AGAP5	AGAP5	413	0	1	0	0.6565569	FALSE	0	AGAP5	0	0
790948	taxon:9606	2.97274303	0	170628	1902	F-box protein 40	gene	biological_process-&-1&-GO:0042692-&&-muscle cell differentiation-%%-GO:0000209-&&-protein polyubiquitination|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008270-&&-zinc ion binding-%%-GO:0003674-&&-molecular_function-%%-GO:0004842-&&-ubiquitin-protein transferase activity-%%-GO:0061630-&&-ubiquitin protein ligase activity	G:9606:FBXO40				FBXO40	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FBXO40	0.33638965	0	1	5	FALSE	FBXO40	FBXO40	636	0	1	0	0.6712095	FALSE	0	FBXO40	0	0
791009	taxon:9606	3.89821963	0	170403	1902	proprotein convertase subtilisin/kexin type 4	gene	biological_process-&-1&-GO:0009566-&&-fertilization-%%-GO:0007339-&&-binding of sperm to zona pellucida-%%-GO:0016485-&&-protein processing-%%-GO:0007340-&&-acrosome reaction-%%-GO:0022414-&&-reproductive process-%%-GO:0048240-&&-sperm capacitation|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0001669-&&-acrosomal vesicle-%%-GO:0002080-&&-acrosomal membrane|molecular_function-&-1&-GO:0004252-&&-serine-type endopeptidase activity-%%-GO:0005515-&&-protein binding	G:9606:PCSK4				PCSK4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PCSK4	0.25652736	0	1	6	FALSE	PCSK4	PCSK4	23	0	1	0	0.51696339	FALSE	0	PCSK4	0	0
791013	taxon:9606	3.15928785	0	170385	1902	basonuclin 2	gene	biological_process-&-1&-GO:0060485-&&-mesenchyme development-%%-GO:0003416-&&-endochondral bone growth-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0043586-&&-tongue development-%%-GO:0060021-&&-palate development-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0005829-&&-cytosol|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding	G:9606:BNC2				BNC2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BNC2	0.31652703	0	1	5	FALSE	BNC2	BNC2	263	0	1	0	0.64011869	FALSE	0	BNC2	0	0
791112	taxon:9606	2.97274303	0	170006	1902	serine/threonine kinase 32B	gene	biological_process-&-1&-GO:0035556-&&-intracellular signal transduction-%%-GO:0018105-&&-peptidyl-serine phosphorylation|cellular_component-&-1&-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0004674-&&-protein serine/threonine kinase activity	G:9606:STK32B				STK32B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-STK32B	0.33638965	0	1	5	FALSE	STK32B	STK32B	636	0	1	0	0.6712095	FALSE	0	STK32B	0	0
791240	taxon:9606	3.14573814	0	169558	1902	carboxypeptidase X, M14 family member 1	gene	biological_process-&-1&-GO:0016485-&&-protein processing-%%-GO:0006518-&&-peptide metabolic process|cellular_component-&-1&-GO:0005615-&&-extracellular space|molecular_function-&-1&-GO:0004181-&&-metallocarboxypeptidase activity-%%-GO:0008270-&&-zinc ion binding	G:9606:CPXM1				CPXM1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CPXM1	0.31789041	0	1	5	FALSE	CPXM1	CPXM1	271	0	1	0	0.64237698	FALSE	0	CPXM1	0	0
791345	taxon:9606	3.48873484	0	169069	1902	GUF1 homolog, GTPase	gene	biological_process-&-1&-GO:0006412-&&-translation|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane|molecular_function-&-1&-GO:0005525-&&-GTP binding-%%-GO:0003924-&&-GTPase activity	G:9606:GUF1				GUF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUF1	0.28663686	0	1	5	FALSE	GUF1	GUF1	111	0	1	0	0.58521086	FALSE	0	GUF1	0	0
791356	taxon:9606	3.24562786	0	169039	1902	PBX/knotted 1 homeobox 2	gene	biological_process-&-1&-GO:0006357-&&-regulation of transcription from RNA polymerase II promoter|cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0045171-&&-intercellular bridge-%%-GO:0005737-&&-cytoplasm-%%-GO:0005654-&&-nucleoplasm-%%-GO:0015630-&&-microtubule cytoskeleton-%%-GO:0015629-&&-actin cytoskeleton|molecular_function-&-1&-GO:0003785-&&-actin monomer binding-%%-GO:0051015-&&-actin filament binding-%%-GO:0000977-&&-RNA polymerase II regulatory region sequence-specific DNA binding	G:9606:PKNOX2				PKNOX2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PKNOX2	0.3081068	0	1	5	FALSE	PKNOX2	PKNOX2	188	0	1	0	0.62572869	FALSE	0	PKNOX2	0	0
791480	taxon:9606	3.31763038	0	168462	1902	tumor protein p53 regulated apoptosis inducing protein 1	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0042981-&&-regulation of apoptotic process|cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0003674-&&-molecular_function	G:9606:TP53AIP1			KEGG-&-1&-hsa04115-&&-p53 signaling pathway-%%-hsa04210-&&-Apoptosis	TP53AIP1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TP53AIP1	0.30141996	0	1	5	FALSE	TP53AIP1	TP53AIP1	117	0	1	0	0.61372827	FALSE	0	TP53AIP1	0	0
791528	taxon:9606	2.91302978	0	168239	1902	SH3 domain containing 21	gene	cellular_component-&-1&-GO:0005634-&&-nucleus-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005654-&&-nucleoplasm	G:9606:SH3D21				SH3D21	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SH3D21	0.3432852	0	1	5	FALSE	SH3D21	SH3D21	930	0	1	0	0.6811617	FALSE	0	SH3D21	0	0
791579	taxon:9606	3.3248779	0	167936	1902	hexokinase domain containing 1	gene	biological_process-&-1&-GO:0051156-&&-glucose 6-phosphate metabolic process-%%-GO:0001678-&&-cellular glucose homeostasis-%%-GO:0019318-&&-hexose metabolic process-%%-GO:0046835-&&-carbohydrate phosphorylation-%%-GO:0006096-&&-glycolytic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005739-&&-mitochondrion|molecular_function-&-1&-GO:0019158-&&-mannokinase activity-%%-GO:0005524-&&-ATP binding-%%-GO:0008865-&&-fructokinase activity-%%-GO:0005536-&&-glucose binding-%%-GO:0004340-&&-glucokinase activity	G:9606:HKDC1			KEGG-&-1&-hsa04930-&&-Type II diabetes mellitus-%%-hsa00051-&&-Fructose and mannose metabolism-%%-hsa04910-&&-Insulin signaling pathway-%%-hsa01100-&&-Metabolic pathways-%%-hsa05230-&&-Central carbon metabolism in cancer-%%-hsa00520-&&-Amino sugar and nucleotide sugar metabolism-%%-hsa00052-&&-Galactose metabolism-%%-hsa01200-&&-Carbon metabolism-%%-hsa00010-&&-Glycolysis / Gluconeogenesis-%%-hsa04973-&&-Carbohydrate digestion and absorption-%%-hsa00500-&&-Starch and sucrose metabolism-%%-hsa00524-&&-Neomycin, kanamycin and gentamicin biosynthesis-%%-hsa04066-&&-HIF-1 signaling pathway	HKDC1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HKDC1	0.30076292	0	1	5	FALSE	HKDC1	HKDC1	150	0	1	0	0.61252035	FALSE	0	HKDC1	0	0
791680	taxon:9606	2.92106507	0	167456	1902	ring finger protein 39	gene	biological_process-&-1&-GO:0008150-&&-biological_process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005575-&&-cellular_component|molecular_function-&-1&-GO:0008270-&&-zinc ion binding	G:9606:RNF39				RNF39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RNF39	0.34234088	0	1	5	FALSE	RNF39	RNF39	942	0	1	0	0.67982249	FALSE	0	RNF39	0	0
791701	taxon:9606	2.92106507	0	167312	1902	Fc fragment of IgA and IgM receptor	gene	biological_process-&-1&-GO:0050900-&&-leukocyte migration-%%-GO:0002250-&&-adaptive immune response|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane	G:9606:FCAMR				FCAMR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-FCAMR	0.34234088	0	1	5	FALSE	FCAMR	FCAMR	942	0	1	0	0.67982249	FALSE	0	FCAMR	0	0
791739	taxon:9606	2.97274303	0	167105	1902	ribosomal protein S6 kinase like 1	gene	biological_process-&-1&-GO:0007165-&&-signal transduction-%%-GO:0006468-&&-protein phosphorylation|cellular_component-&-1&-GO:0005840-&&-ribosome-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0005524-&&-ATP binding	G:9606:RPS6KL1				RPS6KL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-RPS6KL1	0.33638965	0	1	5	FALSE	RPS6KL1	RPS6KL1	636	0	1	0	0.6712095	FALSE	0	RPS6KL1	0	0
791797	taxon:9606	3.61194265	0	166821	1902	methyltransferase like 26	gene		G:9606:METTL26				METTL26	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-METTL26	0.27685932	0	1	5	FALSE	METTL26	METTL26	47	0	1	0	0.56467622	FALSE	0	METTL26	0	0
792033	taxon:9606	3.51126516	0	166327	1902	dermatan sulfate epimerase-like	gene	biological_process-&-1&-GO:0030204-&&-chondroitin sulfate metabolic process-%%-GO:0030208-&&-dermatan sulfate biosynthetic process|cellular_component-&-1&-GO:0000139-&&-Golgi membrane-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0047757-&&-chondroitin-glucuronate 5-epimerase activity-%%-GO:0008146-&&-sulfotransferase activity	G:9606:DSEL				DSEL	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DSEL	0.28479763	0	1	5	FALSE	DSEL	DSEL	90	0	1	0	0.58145581	FALSE	0	DSEL	0	0
792065	taxon:9606	3.06065858	0	166286	1902	BICD family like cargo adaptor 1	gene	biological_process-&-1&-GO:0031175-&&-neuron projection development-%%-GO:0055107-&&-Golgi to secretory granule transport|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005813-&&-centrosome|molecular_function-&-1&-GO:0034452-&&-dynactin binding-%%-GO:0017137-&&-Rab GTPase binding	G:9606:BICDL1				BICDL1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-BICDL1	0.32672707	0	1	5	FALSE	BICDL1	BICDL1	413	0	1	0	0.6565569	FALSE	0	BICDL1	0	0
792238	taxon:9606	3.12210493	0	165981	1902	transmembrane protein 44	gene	cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005765-&&-lysosomal membrane|molecular_function-&-1&-GO:0015189-&&-L-lysine transmembrane transporter activity-%%-GO:0015174-&&-basic amino acid transmembrane transporter activity-%%-GO:0015181-&&-arginine transmembrane transporter activity	G:9606:TMEM44				TMEM44	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-TMEM44	0.32029673	0	1	5	FALSE	TMEM44	TMEM44	310	0	1	0	0.64631584	FALSE	0	TMEM44	0	0
792370	taxon:9606	3.06774854	0	165753	1902	thioesterase superfamily member 4	gene	biological_process-&-1&-GO:0006631-&&-fatty acid metabolic process-%%-GO:1902108-&&-regulation of mitochondrial membrane permeability involved in apoptotic process-%%-GO:0043491-&&-protein kinase B signaling-%%-GO:0035338-&&-long-chain fatty-acyl-CoA biosynthetic process|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0005759-&&-mitochondrial matrix-%%-GO:0005886-&&-plasma membrane-%%-GO:0005739-&&-mitochondrion-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0032587-&&-ruffle membrane|molecular_function-&-1&-GO:0047617-&&-acyl-CoA hydrolase activity-%%-GO:0102991-&&-myristoyl-CoA hydrolase activity-%%-GO:0016290-&&-palmitoyl-CoA hydrolase activity	G:9606:THEM4			KEGG-&-1&-hsa04151-&&-PI3K-Akt signaling pathway-%%-hsa00062-&&-Fatty acid elongation	THEM4	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-THEM4	0.32597196	0	1	5	FALSE	THEM4	THEM4	335	0	1	0	0.65537524	FALSE	0	THEM4	0	0
792582	taxon:9606	3.81250985	0	181768	1902	CD5 molecule like	gene	biological_process-&-1&-GO:0006915-&&-apoptotic process-%%-GO:0002376-&&-immune system process-%%-GO:0006954-&&-inflammatory response-%%-GO:0006898-&&-receptor-mediated endocytosis-%%-GO:0006968-&&-cellular defense response|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome-%%-GO:0005615-&&-extracellular space-%%-GO:0072562-&&-blood microparticle-%%-GO:0005576-&&-extracellular region-%%-GO:0016020-&&-membrane|molecular_function-&-1&-GO:0005044-&&-scavenger receptor activity	G:9606:CD5L				CD5L	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CD5L	0.2622944	0	1	5	FALSE	CD5L	CD5L	13	0	1	0	0.53124836	FALSE	0	CD5L	0	0
792621	taxon:9606	3.06065858	0	165322	1902	gametocyte specific factor 1	gene	biological_process-&-1&-GO:0007283-&&-spermatogenesis-%%-GO:0030154-&&-cell differentiation|cellular_component-&-1&-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0046872-&&-metal ion binding	G:9606:GTSF1				GTSF1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GTSF1	0.32672707	0	1	5	FALSE	GTSF1	GTSF1	413	0	1	0	0.6565569	FALSE	0	GTSF1	0	0
792638	taxon:9606	3.06065858	0	165286	1902	sperm acrosome associated 7	gene	biological_process-&-1&-GO:0007162-&&-negative regulation of cell adhesion-%%-GO:0007338-&&-single fertilization|cellular_component-&-1&-GO:0005576-&&-extracellular region-%%-GO:0043160-&&-acrosomal lumen-%%-GO:0001669-&&-acrosomal vesicle	G:9606:SPACA7				SPACA7	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-SPACA7	0.32672707	0	1	5	FALSE	SPACA7	SPACA7	413	0	1	0	0.6565569	FALSE	0	SPACA7	0	0
792655	taxon:9606	3.5720813	0	181629	1902	cytochrome P450 family 2 subfamily C member 19	gene	biological_process-&-1&-GO:0019373-&&-epoxygenase P450 pathway-%%-GO:0006805-&&-xenobiotic metabolic process-%%-GO:0016098-&&-monoterpenoid metabolic process-%%-GO:0008202-&&-steroid metabolic process-%%-GO:0017144-&&-drug metabolic process-%%-GO:0046483-&&-heterocycle metabolic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0042738-&&-exogenous drug catabolic process-%%-GO:0097267-&&-omega-hydroxylase P450 pathway|cellular_component-&-1&-GO:0031090-&&-organelle membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane-%%-GO:0043231-&&-intracellular membrane-bounded organelle|molecular_function-&-1&-GO:0004497-&&-monooxygenase activity-%%-GO:0019825-&&-oxygen binding-%%-GO:0016491-&&-oxidoreductase activity-%%-GO:0018675-&&-(S)-limonene 6-monooxygenase activity-%%-GO:0008395-&&-steroid hydroxylase activity-%%-GO:0005506-&&-iron ion binding-%%-GO:0008392-&&-arachidonic acid epoxygenase activity-%%-GO:0019899-&&-enzyme binding-%%-GO:0020037-&&-heme binding-%%-GO:0052741-&&-(R)-limonene 6-monooxygenase activity-%%-GO:0018676-&&-(S)-limonene 7-monooxygenase activity	G:9606:CYP2C19			KEGG-&-1&-hsa04726-&&-Serotonergic synapse-%%-hsa01100-&&-Metabolic pathways-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa00591-&&-Linoleic acid metabolism-%%-hsa00590-&&-Arachidonic acid metabolism-%%-hsa05204-&&-Chemical carcinogenesis	CYP2C19	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-CYP2C19	0.27994884	0	1	5	FALSE	CYP2C19	CYP2C19	37	0	1	0	0.57131978	FALSE	0	CYP2C19	0	0
792733	taxon:9606	2.97274303	0	181482	1902	distal-less homeobox 6	gene	biological_process-&-1&-GO:0050679-&&-positive regulation of epithelial cell proliferation-%%-GO:0030855-&&-epithelial cell differentiation-%%-GO:0001501-&&-skeletal system development-%%-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0042472-&&-inner ear morphogenesis-%%-GO:0007399-&&-nervous system development-%%-GO:0060021-&&-palate development-%%-GO:0060322-&&-head development-%%-GO:0030326-&&-embryonic limb morphogenesis-%%-GO:0048646-&&-anatomical structure formation involved in morphogenesis|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding-%%-GO:0043565-&&-sequence-specific DNA binding	G:9606:DLX6				DLX6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-DLX6	0.33638965	0	1	5	FALSE	DLX6	DLX6	636	0	1	0	0.6712095	FALSE	0	DLX6	0	0
792776	taxon:9606	3.15723964	0	148621	1902	zinc finger protein 605	gene	biological_process-&-1&-GO:0006355-&&-regulation of transcription, DNA-templated-%%-GO:0006351-&&-transcription, DNA-templated|cellular_component-&-1&-GO:0005634-&&-nucleus|molecular_function-&-1&-GO:0003677-&&-DNA binding-%%-GO:0046872-&&-metal ion binding-%%-GO:0003700-&&-transcription factor activity, sequence-specific DNA binding	G:9606:ZNF605				ZNF605	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ZNF605	0.31673237	0	1	5	FALSE	ZNF605	ZNF605	202	0	1	0	0.64046006	FALSE	0	ZNF605	0	0
792881	taxon:9606	2.97274303	0	164846	1902	activin A receptor type 1C	gene	biological_process-&-1&-GO:0002021-&&-response to dietary excess-%%-GO:0043280-&&-positive regulation of cysteine-type endopeptidase activity involved in apoptotic process-%%-GO:0046676-&&-negative regulation of insulin secretion-%%-GO:0030154-&&-cell differentiation-%%-GO:1901164-&&-negative regulation of trophoblast cell migration-%%-GO:1901383-&&-negative regulation of chorionic trophoblast cell proliferation-%%-GO:0009749-&&-response to glucose-%%-GO:0023014-&&-signal transduction by protein phosphorylation-%%-GO:0038092-&&-nodal signaling pathway-%%-GO:0030262-&&-apoptotic nuclear changes-%%-GO:0032868-&&-response to insulin-%%-GO:0006468-&&-protein phosphorylation-%%-GO:0019915-&&-lipid storage|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0048179-&&-activin receptor complex|molecular_function-&-1&-GO:0005524-&&-ATP binding-%%-GO:0004702-&&-signal transducer, downstream of receptor, with serine/threonine kinase activity-%%-GO:0019838-&&-growth factor binding-%%-GO:0038100-&&-nodal binding-%%-GO:0016361-&&-activin receptor activity, type I-%%-GO:0004674-&&-protein serine/threonine kinase activity-%%-GO:0046872-&&-metal ion binding	G:9606:ACVR1C			KEGG-&-1&-hsa04550-&&-Signaling pathways regulating pluripotency of stem cells-%%-hsa04060-&&-Cytokine-cytokine receptor interaction-%%-hsa04350-&&-TGF-beta signaling pathway	ACVR1C	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ACVR1C	0.33638965	0	1	5	FALSE	ACVR1C	ACVR1C	636	0	1	0	0.6712095	FALSE	0	ACVR1C	0	0
792895	taxon:9606	3.51126516	0	164823	1902	chromosome 2 open reading frame 50	gene	molecular_function-&-1&-GO:0005515-&&-protein binding	G:9606:C2orf50				C2orf50	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-C2orf50	0.28479763	0	1	5	FALSE	C2orf50	C2orf50	90	0	1	0	0.58145581	FALSE	0	C2orf50	0	0
792907	taxon:9606	3.06065858	0	164789	1902	glutamate rich 6	gene		G:9606:ERICH6				ERICH6	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ERICH6	0.32672707	0	1	5	FALSE	ERICH6	ERICH6	413	0	1	0	0.6565569	FALSE	0	ERICH6	0	0
792975	taxon:9606	3.40176461	0	164673	1902	poly(A) binding protein cytoplasmic 5	gene	cellular_component-&-1&-GO:0005759-&&-mitochondrial matrix|molecular_function-&-1&-GO:0000166-&&-nucleotide binding-%%-GO:0003723-&&-RNA binding	G:9606:PABPC5			KEGG-&-1&-hsa03013-&&-RNA transport-%%-hsa03018-&&-RNA degradation-%%-hsa03015-&&-mRNA surveillance pathway	PABPC5	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PABPC5	0.29396508	0	1	5	FALSE	PABPC5	PABPC5	122	0	1	0	0.5997059	FALSE	0	PABPC5	0	0
793012	taxon:9606	3.12210493	0	180898	1902	G protein-coupled receptor 39	gene	biological_process-&-1&-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0046872-&&-metal ion binding	G:9606:GPR39				GPR39	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GPR39	0.32029673	0	1	5	FALSE	GPR39	GPR39	310	0	1	0	0.64631584	FALSE	0	GPR39	0	0
793060	taxon:9606	3.41011501	0	180816	1902	glutathione S-transferase theta 2 (gene/pseudogene)	gene	cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0070062-&&-extracellular exosome|molecular_function-&-1&-GO:0004364-&&-glutathione transferase activity	G:9606:GSTT2			KEGG-&-1&-hsa00980-&&-Metabolism of xenobiotics by cytochrome P450-%%-hsa00480-&&-Glutathione metabolism-%%-hsa00983-&&-Drug metabolism - other enzymes-%%-hsa05418-&&-Fluid shear stress and atherosclerosis-%%-hsa00982-&&-Drug metabolism - cytochrome P450-%%-hsa05200-&&-Pathways in cancer-%%-hsa01524-&&-Platinum drug resistance-%%-hsa05204-&&-Chemical carcinogenesis-%%-hsa05225-&&-Hepatocellular carcinoma	GSTT2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GSTT2	0.29324524	0	1	5	FALSE	GSTT2	GSTT2	52	0	1	0	0.59831416	FALSE	0	GSTT2	0	0
793090	taxon:9606	3.46005987	0	180749	1902	leucine rich repeat containing 32	gene	biological_process-&-1&-GO:0050710-&&-negative regulation of cytokine secretion-%%-GO:0046007-&&-negative regulation of activated T cell proliferation-%%-GO:0010628-&&-positive regulation of gene expression|cellular_component-&-1&-GO:0005887-&&-integral component of plasma membrane	G:9606:LRRC32				LRRC32	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-LRRC32	0.28901234	0	1	5	FALSE	LRRC32	LRRC32	94	0	1	0	0.58999002	FALSE	0	LRRC32	0	0
793129	taxon:9606	3.80699543	0	164294	1902	proline rich membrane anchor 1	gene	biological_process-&-1&-GO:0042135-&&-neurotransmitter catabolic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0045202-&&-synapse-%%-GO:0030054-&&-cell junction	G:9606:PRIMA1				PRIMA1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-PRIMA1	0.26267434	0	1	5	FALSE	PRIMA1	PRIMA1	11	0	1	0	0.53216743	FALSE	0	PRIMA1	0	0
793206	taxon:9606	3.68945959	0	180531	1902	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2	gene	biological_process-&-1&-GO:0006702-&&-androgen biosynthetic process-%%-GO:0006704-&&-glucocorticoid biosynthetic process-%%-GO:0006705-&&-mineralocorticoid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006694-&&-steroid biosynthetic process|cellular_component-&-1&-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0031966-&&-mitochondrial membrane-%%-GO:0030868-&&-smooth endoplasmic reticulum membrane-%%-GO:0005783-&&-endoplasmic reticulum-%%-GO:0016021-&&-integral component of membrane-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0003854-&&-3-beta-hydroxy-delta5-steroid dehydrogenase activity-%%-GO:0004769-&&-steroid delta-isomerase activity	G:9606:HSD3B2	HSD3B2	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	HSD3B2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD3B2	0.27104241	0	1	5	FALSE	HSD3B2	HSD3B2	57	0	1	0	0.55175674	FALSE	0	HSD3B2	0	0
793234	taxon:9606	3.17961242	0	180481	1902	5-hydroxytryptamine receptor 1F	gene	biological_process-&-1&-GO:0098664-&&-G-protein coupled serotonin receptor signaling pathway-%%-GO:0007268-&&-chemical synaptic transmission-%%-GO:0007193-&&-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-%%-GO:0007187-&&-G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger|cellular_component-&-1&-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane|molecular_function-&-1&-GO:0004993-&&-G-protein coupled serotonin receptor activity-%%-GO:0030594-&&-neurotransmitter receptor activity-%%-GO:0051378-&&-serotonin binding	G:9606:HTR1F			KEGG-&-1&-hsa04024-&&-cAMP signaling pathway-%%-hsa04726-&&-Serotonergic synapse-%%-hsa04742-&&-Taste transduction-%%-hsa04080-&&-Neuroactive ligand-receptor interaction	HTR1F	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HTR1F	0.31450374	0	1	5	FALSE	HTR1F	HTR1F	196	0	1	0	0.63673126	FALSE	0	HTR1F	0	0
793259	taxon:9606	3.06065858	0	180413	1902	guanylate cyclase activator 1A	gene	biological_process-&-1&-GO:0007601-&&-visual perception-%%-GO:0071277-&&-cellular response to calcium ion-%%-GO:0007165-&&-signal transduction-%%-GO:0031284-&&-positive regulation of guanylate cyclase activity-%%-GO:0007602-&&-phototransduction-%%-GO:0000272-&&-polysaccharide catabolic process-%%-GO:0022400-&&-regulation of rhodopsin mediated signaling pathway|cellular_component-&-1&-GO:0001917-&&-photoreceptor inner segment-%%-GO:0097381-&&-photoreceptor disc membrane|molecular_function-&-1&-GO:0008048-&&-calcium sensitive guanylate cyclase activator activity-%%-GO:0005509-&&-calcium ion binding-%%-GO:0030249-&&-guanylate cyclase regulator activity	G:9606:GUCA1A			KEGG-&-1&-hsa04744-&&-Phototransduction	GUCA1A	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GUCA1A	0.32672707	0	1	5	FALSE	GUCA1A	GUCA1A	413	0	1	0	0.6565569	FALSE	0	GUCA1A	0	0
793296	taxon:9606	1	0	180362	1902	hyaluronan synthase 3	gene	biological_process-&-1&-GO:0085029-&&-extracellular matrix assembly-%%-GO:0007155-&&-cell adhesion-%%-GO:0030213-&&-hyaluronan biosynthetic process-%%-GO:1900106-&&-positive regulation of hyaluranon cable assembly-%%-GO:0045893-&&-positive regulation of transcription, DNA-templated-%%-GO:0005975-&&-carbohydrate metabolic process-%%-GO:0045226-&&-extracellular polysaccharide biosynthetic process|cellular_component-&-1&-GO:0005737-&&-cytoplasm-%%-GO:0005886-&&-plasma membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0036117-&&-hyaluranon cable-%%-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0050501-&&-hyaluronan synthase activity	G:9606:HAS3				HAS3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HAS3	1	0	1	1	FALSE	HAS3	HAS3	1	0	1	0	1	FALSE	0	HAS3	0	0
787274	taxon:9606	0	0	163382	1902	adhesion G protein-coupled receptor F3	gene	biological_process-&-1&-GO:0007166-&&-cell surface receptor signaling pathway-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway|cellular_component-&-1&-GO:0016021-&&-integral component of membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity	G:9606:ADGRF3				ADGRF3	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-ADGRF3	0	0	0	0	TRUE	ADGRF3	ADGRF3	0	0	0	0	9.22E+10	FALSE	0	ADGRF3	0	0
790680	taxon:9606	0	0	171487	1902	N-6 adenine-specific DNA methyltransferase 1 (putative)	gene	biological_process-&-1&-GO:0006415-&&-translational termination-%%-GO:0006479-&&-protein methylation-%%-GO:0030307-&&-positive regulation of cell growth-%%-GO:0032259-&&-methylation|cellular_component-&-1&-GO:0005829-&&-cytosol-%%-GO:0043234-&&-protein complex-%%-GO:0005737-&&-cytoplasm|molecular_function-&-1&-GO:0008757-&&-S-adenosylmethionine-dependent methyltransferase activity-%%-GO:0003676-&&-nucleic acid binding-%%-GO:0005515-&&-protein binding-%%-GO:0008276-&&-protein methyltransferase activity	G:9606:N6AMT1				N6AMT1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-N6AMT1	0	0	0	0	TRUE	N6AMT1	N6AMT1	0	0	0	0	9.22E+10	FALSE	0	N6AMT1	0	0
791765	taxon:9606	0	0	166967	1902	pyroglutamylated RFamide peptide receptor	gene	biological_process-&-1&-GO:0032870-&&-cellular response to hormone stimulus-%%-GO:0007186-&&-G-protein coupled receptor signaling pathway-%%-GO:0007218-&&-neuropeptide signaling pathway-%%-GO:1901652-&&-response to peptide|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005887-&&-integral component of plasma membrane-%%-GO:0005886-&&-plasma membrane|molecular_function-&-1&-GO:0004930-&&-G-protein coupled receptor activity-%%-GO:0004983-&&-neuropeptide Y receptor activity-%%-GO:0042277-&&-peptide binding	G:9606:QRFPR				QRFPR	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-QRFPR	0	0	0	0	TRUE	QRFPR	QRFPR	0	0	0	0	9.22E+10	FALSE	0	QRFPR	0	0
791874	taxon:9606	0	0	133798	1902	uroplakin 3B	gene	biological_process-&-1&-GO:0010629-&&-negative regulation of gene expression|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0070062-&&-extracellular exosome	G:9606:UPK3B				UPK3B	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-UPK3B	0	0	0	0	TRUE	UPK3B	UPK3B	0	0	0	0	9.22E+10	FALSE	0	UPK3B	0	0
793121	taxon:9606	0	0	180695	1902	GDNF family receptor alpha 2	gene	biological_process-&-1&-GO:0007411-&&-axon guidance-%%-GO:1903263-&&-positive regulation of serine phosphorylation of STAT3 protein-%%-GO:0031953-&&-negative regulation of protein autophosphorylation-%%-GO:0007169-&&-transmembrane receptor protein tyrosine kinase signaling pathway-%%-GO:0000165-&&-MAPK cascade-%%-GO:0035860-&&-glial cell-derived neurotrophic factor receptor signaling pathway-%%-GO:0043547-&&-positive regulation of GTPase activity|cellular_component-&-1&-GO:0019898-&&-extrinsic component of membrane-%%-GO:0031225-&&-anchored component of membrane-%%-GO:0005886-&&-plasma membrane-%%-GO:0005622-&&-intracellular|molecular_function-&-1&-GO:0005088-&&-Ras guanyl-nucleotide exchange factor activity-%%-GO:0016167-&&-glial cell-derived neurotrophic factor receptor activity	G:9606:GFRA2				GFRA2	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-GFRA2	0	0	0	0	TRUE	GFRA2	GFRA2	0	0	0	0	9.22E+10	FALSE	0	GFRA2	0	0
793202	taxon:9606	0	0	180532	1902	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1	gene	biological_process-&-1&-GO:0006694-&&-steroid biosynthetic process-%%-GO:0006702-&&-androgen biosynthetic process-%%-GO:0006704-&&-glucocorticoid biosynthetic process-%%-GO:0006705-&&-mineralocorticoid biosynthetic process-%%-GO:0055114-&&-oxidation-reduction process-%%-GO:0006703-&&-estrogen biosynthetic process|cellular_component-&-1&-GO:0016021-&&-integral component of membrane-%%-GO:0030868-&&-smooth endoplasmic reticulum membrane-%%-GO:0005743-&&-mitochondrial inner membrane-%%-GO:0005758-&&-mitochondrial intermembrane space-%%-GO:0005789-&&-endoplasmic reticulum membrane|molecular_function-&-1&-GO:0004769-&&-steroid delta-isomerase activity-%%-GO:0003854-&&-3-beta-hydroxy-delta5-steroid dehydrogenase activity	G:9606:HSD3B1	HSD3B1	TRUE	KEGG-&-1&-hsa04913-&&-Ovarian steroidogenesis-%%-hsa04925-&&-Aldosterone synthesis and secretion-%%-hsa00140-&&-Steroid hormone biosynthesis-%%-hsa01100-&&-Metabolic pathways-%%-hsa04934-&&-Cushing syndrome-%%-hsa04927-&&-Cortisol synthesis and secretion	HSD3B1	Homo sapiens (Human)-&&-9606	Gene Symbol-&-1&-HSD3B1	0	0	0	0	TRUE	HSD3B1	HSD3B1	0	0	0	0	9.22E+10	FALSE	0	HSD3B1	0	0
																		29