MetaDraft Gene Report

Analysis

Input fasta: test.fasta
Metaproteome used: bigg2-eco41
Report date: 20-11-02
MetaDraft version: 0.9.3

Genes (33:33)

Input genes not matched

stu0265, stu0262, stu0246, stu1886, stu1869, stu0160, stu0762, stu0763, stu1589, stu0117, stu0505, stu0507, stu0692, stu0596, stu0987

Genes selected

SourceTargetScoreModel
stu0163b37841.0bigg2-eco41
stu0264b38491.0bigg2-eco41
stu0355b24981.0bigg2-eco41
stu0501b06771.0bigg2-eco41
stu0590b37701.0bigg2-eco41
stu0603b42541.0bigg2-eco41
stu0606b08091.0bigg2-eco41
stu0697b43951.0bigg2-eco41
stu0720b39081.0bigg2-eco41
stu0761b05941.0bigg2-eco41
stu0785b38291.0bigg2-eco41
stu0846b24141.0bigg2-eco41
stu0847b39391.0bigg2-eco41
stu0848b36071.0bigg2-eco41
stu0936b03561.0bigg2-eco41
stu1012b34281.0bigg2-eco41
stu1013b34161.0bigg2-eco41
stu1164b06531.0bigg2-eco41
stu1167b31891.0bigg2-eco41
stu1169b07591.0bigg2-eco41
stu1264b24161.0bigg2-eco41
stu1265b24151.0bigg2-eco41
stu1266b11361.0bigg2-eco41
stu1267b03331.0bigg2-eco41
stu1268b12761.0bigg2-eco41
stu1460b12071.0bigg2-eco41
stu1461b25301.0bigg2-eco41
stu1492b08111.0bigg2-eco41
stu1583b03811.0bigg2-eco41
stu1588b12611.0bigg2-eco41
stu1640b09021.0bigg2-eco41
stu1648b36341.0bigg2-eco41
stu1711b02421.0bigg2-eco41

Genes not selected

SourceTargetScoreModel
stu0264b13630.219bigg2-eco41
stu0603b02730.801bigg2-eco41
stu1012b34170.186bigg2-eco41
stu1164b08100.063bigg2-eco41

Annotation


GeneMatch: 0163 --> b3784 (top)
Matching Gene Information: b3784
functionenzyme; Central intermediary metabolism: Sugar-nucleotide biosynthesis, conversions 1.6.4 metabolism; macromolecules (cellular constituent) biosynthesis; enterobacterial common antigen (surface glycolipid) 6.3 cell structure; surface antigens (ECA, O antigen of LPS)
GO_functionGO:0042280 - cell surface antigen activity, host-interacting
gene_synonymECK3776; JW3758; wecA
EC_number2.4.1.-
productUDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase
GO_processGO:0009246 - enterobacterial common antigen biosynthetic process
generfe
protein_idNP_418231.1
db_xrefGI:16131640
ASAP:ABE-0012366
UniProtKB/Swiss-Prot:P0AC78
ECOCYC:EG10840
EcoGene:EG10840
GeneID:948789
Associated reactions(s)
R_ACGAMT (bigg2-eco41)UDP-N-acetylglucosamine:undecaprenylphosphate N-acetylglucosamine -1-phosphate transferase
b3784

GeneMatch: 0264 --> b3849 (top)
Matching Gene Information: b3849
functiontransport; Transport of small molecules: Cations
GO_componentGO:0019866 - organelle inner membrane;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK3841; JW5576; sapJ
notepotassium uptake, requires TrkE
genetrkH
productpotassium transporter
protein_idYP_026273.1
db_xrefGI:49176432
ASAP:ABE-0012574
UniProtKB/Swiss-Prot:P0AFZ7
ECOCYC:EG11021
EcoGene:EG11021
GeneID:948333
Associated reactions(s)
R_Kt2r (bigg2-eco41)Potassium reversible transport via proton symport
((b1363 or b3849))

GeneMatch: 0355 --> b2498 (top)
Matching Gene Information: b2498
functionenzyme; Salvage of nucleosides and nucleotides
gene_synonymECK2494; JW2483; uraP
EC_number2.4.2.9
producturacil phosphoribosyltransferase
GO_processGO:0015949 - nucleobase, nucleoside and nucleotide interconversion
experimentN-terminus verified by Edman degradation: PMID 9298646
protein_idNP_416993.2
geneupp
db_xrefGI:90111448
ASAP:ABE-0008224
UniProtKB/Swiss-Prot:P0A8F0
ECOCYC:EG11332
EcoGene:EG11332
GeneID:946979
Associated reactions(s)
R_UPPRT (bigg2-eco41)Uracil phosphoribosyltransferase
b2498

GeneMatch: 0501 --> b0677 (top)
Matching Gene Information: b0677
functionenzyme; Central intermediary metabolism: Amino sugars
gene_synonymECK0665; JW0663
EC_number3.5.1.25
productN-acetylglucosamine-6-phosphate deacetylase
GO_processGO:0046349 - amino sugar biosynthetic process
genenagA
protein_idNP_415203.1
db_xrefGI:16128653
ASAP:ABE-0002301
UniProtKB/Swiss-Prot:P0AF18
ECOCYC:EG10632
EcoGene:EG10632
GeneID:945289
Associated reactions(s)
R_AGDC (bigg2-eco41)N-acetylglucosamine-6-phosphate deacetylase
b0677

GeneMatch: 0590 --> b3770 (top)
Matching Gene Information: b3770
functionenzyme; Amino acid biosynthesis: Isoleucine, Valine
gene_synonymECK3762; JW5606
EC_number2.6.1.42
productbranched-chain amino-acid aminotransferase
GO_processGO:0006523 - alanine biosynthetic process;
GO:0009098 - leucine biosynthetic process
geneilvE
protein_idYP_026247.1
db_xrefGI:49176403
ASAP:ABE-0012316
UniProtKB/Swiss-Prot:P0AB80
ECOCYC:EG10497
EcoGene:EG10497
GeneID:948278
Associated reactions(s)
R_VALTA (bigg2-eco41)Valine transaminase
b3770
R_ILETA (bigg2-eco41)Isoleucine transaminase
b3770
R_PHETA1 (bigg2-eco41)Phenylalanine transaminase
((b0928 or b3770 or b4054))
R_LEUTAi (bigg2-eco41)Leucine transaminase (irreversible)
((b3770 or b4054))

GeneMatch: 0603 --> b4254 (top)
Matching Gene Information: b4254
functionenzyme; Amino acid biosynthesis: Arginine
GO_componentGO:0005737 - cytoplasm
gene_synonymECK4247; JW4211
EC_number2.1.3.3
productornithine carbamoyltransferase 1
GO_processGO:0006526 - arginine biosynthetic process
geneargI
protein_idNP_418675.1
db_xrefGI:16132076
ASAP:ABE-0013927
UniProtKB/Swiss-Prot:P04391
ECOCYC:EG10069
EcoGene:EG10069
GeneID:948774
Associated reactions(s)
R_OCBT (bigg2-eco41)Ornithine carbamoyltransferase
((b4254 or b0273))

GeneMatch: 0606 --> b0809 (top)
Matching Gene Information: b0809
functiontransport; Transport of small molecules: Amino acids, amines
GO_componentGO:0005737 - cytoplasm
gene_synonymECK0798; JW0794
noteATP-binding component of glutamine high-affinity transport system
GO_processGO:0006542 - glutamine biosynthetic process
geneglnQ
productglutamine transporter subunit
protein_idNP_415330.1
db_xrefGI:16128777
ASAP:ABE-0002764
UniProtKB/Swiss-Prot:P10346
ECOCYC:EG10389
EcoGene:EG10389
GeneID:945435
Associated reactions(s)
R_GLNabc (bigg2-eco41)L-glutamine transport via ABC system
((b0810 and b0811 and b0809))

GeneMatch: 0697 --> b4395 (top)
Matching Gene Information: b4395
functionenzyme; Energy metabolism, carbon: Glycolysis
GO_componentGO:0005737 - cytoplasm
gene_synonymECK4387; JW4358; ytjC
notephosphoglyceromutase 2
GO_processGO:0006094 - gluconeogenesis;
GO:0006096 - glycolysis
geneytjC
productpredicted phosphoglyceromutase 2, co-factor independent
protein_idNP_418812.1
db_xrefGI:16132212
ASAP:ABE-0014416
UniProtKB/Swiss-Prot:P0A7A2
ECOCYC:EG12164
EcoGene:EG12164
GeneID:948918
Associated reactions(s)
R_PGM (bigg2-eco41)Phosphoglycerate mutase
((b4395 or b3612 or b0755))

GeneMatch: 0720 --> b3908 (top)
Matching Gene Information: b3908
functionenzyme; Detoxification
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3901; JW3879
EC_number1.15.1.1
notesuperoxide dismutase, manganese
GO_processGO:0006805 - xenobiotic metabolic process
genesodA
productsuperoxide dismutase, Mn
protein_idNP_418344.3
db_xrefGI:49176442
ASAP:ABE-0012761
UniProtKB/Swiss-Prot:P00448
ECOCYC:EG10953
EcoGene:EG10953
GeneID:948403
Associated reactions(s)
R_SPODM (bigg2-eco41)Superoxide dismutase
((b3908 or b1646 or b1656))

GeneMatch: 0761 --> b0594 (top)
Matching Gene Information: b0594
functionenzyme; Biosynthesis of cofactors, carriers: Enterochelin
GO_componentGO:0005737 - cytoplasm;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK0587; JW0586
EC_number2.7.7.58
note2,3-dihydroxybenzoate-AMP ligase
GO_processGO:0009239 - enterobactin biosynthetic process;
GO:0019184 - nonribosomal peptide biosynthetic process
geneentE
product2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex
protein_idNP_415126.1
db_xrefGI:16128577
ASAP:ABE-0002049
UniProtKB/Swiss-Prot:P10378
ECOCYC:EG10263
EcoGene:EG10263
GeneID:947426
Associated reactions(s)
R_DHBSr (bigg2-eco41)2,3-dihydroxybenzoate adenylate synthase
b0594

GeneMatch: 0785 --> b3829 (top)
Matching Gene Information: b3829
functionenzyme; Amino acid biosynthesis: Methionine
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3823; JW3805; metB12
EC_number2.1.1.14
notetetrahydropteroyltriglutamate methyltransferase
GO_processGO:0009086 - methionine biosynthetic process;
GO:0006556 - S-adenosylmethionine biosynthetic process
genemetE
product5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase
protein_idNP_418273.1
db_xrefGI:16131678
ASAP:ABE-0012520
UniProtKB/Swiss-Prot:P25665
ECOCYC:EG10584
EcoGene:EG10584
GeneID:948323
Associated reactions(s)
R_METS_1 (bigg2-eco41)Methionine synthase
((b3829 or b4019))

GeneMatch: 0846 --> b2414 (top)
Matching Gene Information: b2414
functionenzyme; Amino acid biosynthesis: Cysteine
GO_componentGO:0005737 - cytoplasm
gene_synonymcysZ; ECK2409; JW2407
EC_number2.5.1.47
notecysteine synthase A, O-acetylserine sulfhydrolase A
GO_processGO:0019344 - cysteine biosynthetic process
genecysK
productcysteine synthase A, O-acetylserine sulfhydrolase A subunit
protein_idNP_416909.1
db_xrefGI:16130340
ASAP:ABE-0007957
UniProtKB/Swiss-Prot:P0ABK5
ECOCYC:EG10192
EcoGene:EG10192
GeneID:946877
Associated reactions(s)
R_CYSS (bigg2-eco41)Cysteine synthase
((b2414 or b2421))

GeneMatch: 0847 --> b3939 (top)
Matching Gene Information: b3939
functionenzyme; Amino acid biosynthesis: Methionine
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3931; JW3910; met-1
EC_number2.5.1.48
notecystathionine gamma-synthase
GO_processGO:0009063 - cellular amino acid catabolic process;
GO:0009086 - methionine biosynthetic process
genemetB
productcystathionine gamma-synthase, PLP-dependent
protein_idNP_418374.1
db_xrefGI:16131777
ASAP:ABE-0012887
UniProtKB/Swiss-Prot:P00935
ECOCYC:EG10582
EcoGene:EG10582
GeneID:948434
Associated reactions(s)
R_SHSL1 (bigg2-eco41)O-succinylhomoserine lyase (L-cysteine)
b3939

GeneMatch: 0848 --> b3607 (top)
Matching Gene Information: b3607
functionenzyme; Amino acid biosynthesis: Cysteine
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3597; JW3582
EC_number2.3.1.30
productserine acetyltransferase
GO_processGO:0019344 - cysteine biosynthetic process
genecysE
protein_idNP_418064.1
db_xrefGI:16131478
ASAP:ABE-0011793
UniProtKB/Swiss-Prot:P0A9D4
ECOCYC:EG10187
EcoGene:EG10187
GeneID:948126
Associated reactions(s)
R_SERAT (bigg2-eco41)Serine O-acetyltransferase
b3607

GeneMatch: 0936 --> b0356 (top)
Matching Gene Information: b0356
functionenzyme; Energy metabolism, carbon: Fermentation
GO_componentGO:0005737 - cytoplasm
gene_synonymadhC; ECK0353; JW0347
EC_number1.1.1.1 1.1.1.284
notealcohol dehydrogenase class III; formaldehyde dehydrogenase, glutathione-dependent
GO_processGO:0006113 - fermentation
experimentN-terminus verified by Edman degradation: PMID 1731906
protein_idNP_414890.1
genefrmA
productalcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase
db_xrefGI:16128341
ASAP:ABE-0001221
UniProtKB/Swiss-Prot:P25437
ECOCYC:EG50010
EcoGene:EG50010
GeneID:944988
Associated reactions(s)
R_ALCD19 (bigg2-eco41)Alcohol dehydrogenase (glycerol)
b0356
R_LCADi_copy1 (bigg2-eco41)
((b0356 or b1415 or b1300 or b3588))

GeneMatch: 1012 --> b3428 (top)
Matching Gene Information: b3428
functionenzyme; Macromolecule synthesis, modification: Polysaccharides - (cytoplasmic)
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3414; glgY; JW3391
EC_number2.4.1.1
productglycogen phosphorylase
GO_processGO:0016052 - carbohydrate catabolic process;
GO:0000271 - polysaccharide biosynthetic process
geneglgP
protein_idNP_417886.1
db_xrefGI:16131302
ASAP:ABE-0011198
UniProtKB/Swiss-Prot:P0AC86
ECOCYC:EG10380
EcoGene:EG10380
GeneID:947931
Associated reactions(s)
R_GLCP (bigg2-eco41)Glycogen phosphorylase
((b3428 or b3417))

GeneMatch: 1013 --> b3416 (top)
Matching Gene Information: b3416
functionenzyme; Degradation of polysaccharides
GO_componentGO:0005737 - cytoplasm
gene_synonymECK3403; JW3379; malA
EC_number2.4.1.25
product4-alpha-glucanotransferase (amylomaltase)
GO_processGO:0016052 - carbohydrate catabolic process;
GO:0000272 - polysaccharide catabolic process
genemalQ
protein_idNP_417875.1
db_xrefGI:16131292
ASAP:ABE-0011151
UniProtKB/Swiss-Prot:P15977
ECOCYC:EG10561
EcoGene:EG10561
GeneID:947923
Associated reactions(s)
R_AMALT2 (bigg2-eco41)Amylomaltase (maltotetraose)
b3416
R_AMALT3 (bigg2-eco41)Amylomaltase (maltopentaose)
b3416
R_AMALT4 (bigg2-eco41)Amylomaltase (maltohexaose)
b3416
R_AMALT1 (bigg2-eco41)Amylomaltase (maltotriose)
b3416

GeneMatch: 1164 --> b0653 (top)
Matching Gene Information: b0653
functiontransport; Transport of small molecules: Amino acids, amines
GO_componentGO:0019866 - organelle inner membrane;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK0646; JW0648
noteglutamate/aspartate transport system permease; membrane component of ABC superfamily
GO_processGO:0006532 - aspartate biosynthetic process;
GO:0006537 - glutamate biosynthetic process
genegltK
productglutamate and aspartate transporter subunit
protein_idNP_415186.1
db_xrefGI:16128636
ASAP:ABE-0002234
UniProtKB/Swiss-Prot:P0AER5
ECOCYC:EG12662
EcoGene:EG12662
GeneID:947354
Associated reactions(s)
R_GLUabc (bigg2-eco41)L-glutamate transport via ABC system
((b0654 and b0655 and b0652 and b0653))
R_ASPabc (bigg2-eco41)L-aspartate transport via ABC system
((b0654 and b0655 and b0652 and b0653))

GeneMatch: 1167 --> b3189 (top)
Matching Gene Information: b3189
functionenzyme; Murein sacculus, peptidoglycan
GO_componentGO:0009274 - peptidoglycan-based cell wall
gene_synonymECK3178; JW3156; mrbA; murZ
EC_number2.5.1.7
notefirst step in murein biosynthesis;UDP-N-glucosamine 1-carboxyvinyltransferase
GO_processGO:0009252 - peptidoglycan biosynthetic process
experimentN-terminus verified by Edman degradation: PMID 1512209
protein_idNP_417656.1
genemurA
productUDP-N-acetylglucosamine 1-carboxyvinyltransferase
db_xrefGI:16131079
ASAP:ABE-0010479
UniProtKB/Swiss-Prot:P0A749
ECOCYC:EG11358
EcoGene:EG11358
GeneID:947703
Associated reactions(s)
R_UAGCVT (bigg2-eco41)UDP-N-acetylglucosamine 1-carboxyvinyltransferase
b3189

GeneMatch: 1169 --> b0759 (top)
Matching Gene Information: b0759
functionenzyme; Degradation of small molecules: Carbon compounds
GO_componentGO:0005737 - cytoplasm
GO_functionGO:0042280 - cell surface antigen activity, host-interacting
gene_synonymECK0748; galD; JW0742
EC_number5.1.3.2
productUDP-galactose-4-epimerase
GO_processGO:0016052 - carbohydrate catabolic process;
GO:0009242 - colanic acid biosynthetic process;
GO:0006012 - galactose metabolic process;
GO:0009435 - NAD biosynthetic process;
GO:0009269 - response to desiccation
experimentN-terminus verified by Edman degradation: PMID 4613352,9119048
protein_idNP_415280.3
genegalE
db_xrefGI:49176045
ASAP:ABE-0002575
UniProtKB/Swiss-Prot:P09147
ECOCYC:EG10362
EcoGene:EG10362
GeneID:945354
Associated reactions(s)
R_UDPG4E (bigg2-eco41)UDPglucose 4-epimerase
b0759

GeneMatch: 1264 --> b2416 (top)
Matching Gene Information: b2416
functionenzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols
gene_synonymctr; ECK2411; JW2409
EC_number2.7.3.9
notePEP-protein phosphotransferase system enzyme I
GO_processGO:0016052 - carbohydrate catabolic process
experimentN-terminus verified by Edman degradation: PMID 9298646
protein_idNP_416911.1
geneptsI
productPEP-protein phosphotransferase of PTS system (enzyme I)
db_xrefGI:16130342
ASAP:ABE-0007967
UniProtKB/Swiss-Prot:P08839
ECOCYC:EG10789
EcoGene:EG10789
GeneID:946879
Associated reactions(s)
R_GAMpts (bigg2-eco41)D-glucosamine transport via PEP:Pyr PTS
((b2416 and b1819 and b2415 and b1817 and b1818))
R_FRUpts2 (bigg2-eco41)Fructose transport via PEP:Pyr PTS (f6p generating)
((b2416 and b1817 and b1819 and b2415 and b1818))
R_GLCpts (bigg2-eco41)D-glucose transport via PEP:Pyr PTS
(((b2416 and b2417 and b2415 and b1101) or (b2416 and b1819 and b2415 and b1817 and b1818) or (b2416 and b2417 and b2415 and b1621)))
R_DHAPT (bigg2-eco41)Dihydroxyacetone phosphotransferase
((b2416 and b1200 and b2415 and b1198 and b1199))
R_SUCpts (bigg2-eco41)Sucrose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b2429))
R_TREpts (bigg2-eco41)Trehalose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b4240))
R_FRUpts (bigg2-eco41)D-fructose transport via PEP:Pyr PTS
((b2416 and b2169 and b2415 and b2167))
R_MANpts (bigg2-eco41)D-mannose transport via PEP:Pyr PTS
((b2416 and b1817 and b1819 and b2415 and b1818))
R_ACGApts (bigg2-eco41)N-Acetyl-D-glucosamine transport via PEP:Pyr PTS
(((b2416 and b2415 and b0679) or (b2416 and b2417 and b2415 and b1101)))
R_MALTpts (bigg2-eco41)Maltose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b1621 and b4036))
R_GALTpts (bigg2-eco41)Galactitol transport via PEP:Pyr PTS
((b2416 and b2092 and b2415 and b2094 and b2093))
R_SBTpts (bigg2-eco41)D-sorbitol transport via PEP:Pyr PTS
((b2416 and b2703 and b2415 and b2704 and b2702))
R_ACMANApts (bigg2-eco41)N-acetyl-D-mannosamine transport via PTS
((b2416 and b1819 and b2415 and b1817 and b1818))
R_MNLpts (bigg2-eco41)Mannitol transport via PEP:Pyr PTS
((b2416 and b2415 and b3599))

GeneMatch: 1265 --> b2415 (top)
Matching Gene Information: b2415
functionenzyme; Transport of small molecules: Carbohydrates, organic acids, alcohols
gene_synonymctr; ECK2410; Hpr; iex?; JW2408
notePTS system protein HPr
GO_processGO:0016052 - carbohydrate catabolic process
experimentN-terminus verified by Edman degradation: PMID 9298646,9868784,10094700
geneptsH
productphosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr)
protein_idNP_416910.1
db_xrefGI:16130341
ASAP:ABE-0007962
UniProtKB/Swiss-Prot:P0AA04
ECOCYC:EG10788
EcoGene:EG10788
GeneID:946886
Associated reactions(s)
R_GAMpts (bigg2-eco41)D-glucosamine transport via PEP:Pyr PTS
((b2416 and b1819 and b2415 and b1817 and b1818))
R_FRUpts2 (bigg2-eco41)Fructose transport via PEP:Pyr PTS (f6p generating)
((b2416 and b1817 and b1819 and b2415 and b1818))
R_GLCpts (bigg2-eco41)D-glucose transport via PEP:Pyr PTS
(((b2416 and b2417 and b2415 and b1101) or (b2416 and b1819 and b2415 and b1817 and b1818) or (b2416 and b2417 and b2415 and b1621)))
R_DHAPT (bigg2-eco41)Dihydroxyacetone phosphotransferase
((b2416 and b1200 and b2415 and b1198 and b1199))
R_SUCpts (bigg2-eco41)Sucrose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b2429))
R_TREpts (bigg2-eco41)Trehalose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b4240))
R_FRUpts (bigg2-eco41)D-fructose transport via PEP:Pyr PTS
((b2416 and b2169 and b2415 and b2167))
R_MANpts (bigg2-eco41)D-mannose transport via PEP:Pyr PTS
((b2416 and b1817 and b1819 and b2415 and b1818))
R_ACGApts (bigg2-eco41)N-Acetyl-D-glucosamine transport via PEP:Pyr PTS
(((b2416 and b2415 and b0679) or (b2416 and b2417 and b2415 and b1101)))
R_MALTpts (bigg2-eco41)Maltose transport via PEP:Pyr PTS
((b2416 and b2417 and b2415 and b1621 and b4036))
R_GALTpts (bigg2-eco41)Galactitol transport via PEP:Pyr PTS
((b2416 and b2092 and b2415 and b2094 and b2093))
R_SBTpts (bigg2-eco41)D-sorbitol transport via PEP:Pyr PTS
((b2416 and b2703 and b2415 and b2704 and b2702))
R_ACMANApts (bigg2-eco41)N-acetyl-D-mannosamine transport via PTS
((b2416 and b1819 and b2415 and b1817 and b1818))
R_MNLpts (bigg2-eco41)Mannitol transport via PEP:Pyr PTS
((b2416 and b2415 and b3599))

GeneMatch: 1266 --> b1136 (top)
Matching Gene Information: b1136
functionenzyme; Energy metabolism, carbon: TCA cycle; Phage or Prophage Related
gene_synonymECK1122; icdA; icdE; JW1122
EC_number1.1.1.42
noteisocitrate dehydrogenase, specific for NADP+
GO_processGO:0009061 - anaerobic respiration;
GO:0006099 - tricarboxylic acid cycle
experimentN-terminus verified by Edman degradation: PMID 9298646
protein_idNP_415654.1
geneicd
producte14 prophage; isocitrate dehydrogenase, specific for NADP+
db_xrefGI:16129099
ASAP:ABE-0003823
UniProtKB/Swiss-Prot:P08200
ECOCYC:EG10489
EcoGene:EG10489
GeneID:945702
Associated reactions(s)
R_ICDHyr (bigg2-eco41)Isocitrate dehydrogenase (NADP)
b1136

GeneMatch: 1267 --> b0333 (top)
Matching Gene Information: b0333
functionputative enzyme; Not classified
GO_componentGO:0005737 - cytoplasm
gene_synonymECK0330; JW0324; yahS; yzzD
EC_number2.3.3.1
noteputative citrate synthase; propionate metabolism?
GO_processGO:0019395 - fatty acid oxidation
geneprpC
product2-methylcitrate synthase
protein_idNP_414867.1
db_xrefGI:16128318
ASAP:ABE-0001148
UniProtKB/Swiss-Prot:P31660
ECOCYC:G6198
EcoGene:EG11756
GeneID:947528
Associated reactions(s)
R_MCITS (bigg2-eco41)2-methylcitrate synthase
b0333

GeneMatch: 1268 --> b1276 (top)
Matching Gene Information: b1276
functionenzyme; Energy metabolism, carbon: TCA cycle
gene_synonymacn; ECK1271; JW1268
EC_number4.2.1.3
noteaconitate hydrase 1
GO_processGO:0009061 - anaerobic respiration;
GO:0006099 - tricarboxylic acid cycle
geneacnA
productaconitate hydratase 1
protein_idNP_415792.1
db_xrefGI:16129237
ASAP:ABE-0004283
UniProtKB/Swiss-Prot:P25516
ECOCYC:EG11325
EcoGene:EG11325
GeneID:946724
Associated reactions(s)
R_MICITDr (bigg2-eco41)2-methylisocitrate dehydratase
((b1276 or b0118))
R_ACONT (bigg2-eco41)Aconitate hydratase
((b1276 or b0118))

GeneMatch: 1460 --> b1207 (top)
Matching Gene Information: b1207
functionenzyme; Purine ribonucleotide biosynthesis
gene_synonymdnaR; ECK1195; JW1198; prsA
EC_number2.7.6.1
notephosphoribosylpyrophosphate synthetase
GO_processGO:0009152 - purine ribonucleotide biosynthetic process
geneprs
productphosphoribosylpyrophosphate synthase
protein_idNP_415725.1
db_xrefGI:16129170
ASAP:ABE-0004054
UniProtKB/Swiss-Prot:P0A717
ECOCYC:EG10774
EcoGene:EG10774
GeneID:945772
Associated reactions(s)
R_PRPPS (bigg2-eco41)Phosphoribosylpyrophosphate synthetase
b1207

GeneMatch: 1461 --> b2530 (top)
Matching Gene Information: b2530
functionessential for the biosynthesis of 2-selenouridine in tRNA required for the biosynthesis of thiamin, NAD, Fe-S clusters, and thionucleosides 2.2.3 information transfer; RNA related; RNA modification
gene_synonymECK2527; JW2514; nuvC; yfhO; yzzO
EC_number2.8.1.7
notecysteine desulfurase; cysteine desulfurase (tRNA sulfurtransferase) PLP-dependent
GO_processGO:0009451 - RNA modification
experimentN-terminus verified by Edman degradation: PMID 9298646
protein_idYP_026169.1
geneiscS
productcysteine desulfurase (tRNA sulfurtransferase), PLP-dependent
db_xrefGI:49176235
ASAP:ABE-0008324
UniProtKB/Swiss-Prot:P0A6B7
ECOCYC:G7325
EcoGene:EG12677
GeneID:947004
Associated reactions(s)
R_THZPSN (bigg2-eco41)Thiazole phosphate synthesis
((b3990 and b3991 and b3992 and b2530 and b4407 and b0423))

GeneMatch: 1492 --> b0811 (top)
Matching Gene Information: b0811
functiontransport; Transport of small molecules: Amino acids, amines
GO_componentGO:0042597 - periplasmic space
gene_synonymECK0800; JW0796
noteperiplasmic glutamine-binding protein; permease
GO_processGO:0006542 - glutamine biosynthetic process
geneglnH
productglutamine transporter subunit
protein_idNP_415332.1
db_xrefGI:16128779
ASAP:ABE-0002771
UniProtKB/Swiss-Prot:P0AEQ3
ECOCYC:EG10386
EcoGene:EG10386
GeneID:944872
Associated reactions(s)
R_GLNabc (bigg2-eco41)L-glutamine transport via ABC system
((b0810 and b0811 and b0809))

GeneMatch: 1583 --> b0381 (top)
Matching Gene Information: b0381
functionenzyme; Murein sacculus, peptidoglycan
GO_componentGO:0005737 - cytoplasm;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK0376; JW0372
EC_number6.3.2.4
productD-alanine-D-alanine ligase A
GO_processGO:0009252 - peptidoglycan biosynthetic process
geneddlA
protein_idNP_414915.1
db_xrefGI:16128366
ASAP:ABE-0001309
UniProtKB/Swiss-Prot:P0A6J8
ECOCYC:EG10213
EcoGene:EG10213
GeneID:945313
Associated reactions(s)
R_ALAALAr (bigg2-eco41)D-alanine-D-alanine ligase (reversible)
((b0381 or b0092))

GeneMatch: 1588 --> b1261 (top)
Matching Gene Information: b1261
functionenzyme; Amino acid biosynthesis: Tryptophan
GO_componentGO:0005737 - cytoplasm
gene_synonymECK1255; JW1253
EC_number4.2.1.20
notetryptophan synthase, beta protein
GO_processGO:0000162 - tryptophan biosynthetic process
genetrpB
producttryptophan synthase, beta subunit
protein_idNP_415777.1
db_xrefGI:16129222
ASAP:ABE-0004234
UniProtKB/Swiss-Prot:P0A879
ECOCYC:EG11025
EcoGene:EG11025
GeneID:945768
Associated reactions(s)
R_TRPS3 (bigg2-eco41)Tryptophan synthase (indoleglycerol phosphate)
((b1260 and b1261))
R_TRPS1 (bigg2-eco41)Tryptophan synthase (indoleglycerol phosphate)
((b1260 and b1261))
R_TRPS2 (bigg2-eco41)Tryptophan synthase (indole)
((b1260 and b1261))

GeneMatch: 1640 --> b0902 (top)
Matching Gene Information: b0902
functionenzyme; Energy metabolism, carbon: Anaerobic respiration
GO_componentGO:0005737 - cytoplasm
gene_synonymact; ECK0893; JW0885
EC_number1.97.1.4
productpyruvate formate lyase activating enzyme 1
GO_processGO:0009061 - anaerobic respiration;
GO:0006464 - protein modification process
genepflA
protein_idNP_415422.1
db_xrefGI:16128869
ASAP:ABE-0003068
UniProtKB/Swiss-Prot:P0A9N4
ECOCYC:EG10028
EcoGene:EG10028
GeneID:945517
Associated reactions(s)
R_PFL (bigg2-eco41)Pyruvate formate lyase
((b3114 or (b3951 and b3952) or (b0902 and b0903)))
R_OBTFL (bigg2-eco41)2-Oxobutanoate formate lyase
(((b0902 and b0903) or b3114))

GeneMatch: 1648 --> b3634 (top)
Matching Gene Information: b3634
functionputative enzyme; Not classified
GO_functionGO:0042280 - cell surface antigen activity, host-interacting
gene_synonymECK3624; JW3609; kdtB; yicA
EC_number2.7.7.3
productpantetheine-phosphate adenylyltransferase
experimentN-terminus verified by Edman degradation: PMID 10480925
protein_idNP_418091.1
genecoaD
db_xrefGI:16131505
ASAP:ABE-0011875
UniProtKB/Swiss-Prot:P0A6I6
ECOCYC:EG11190
EcoGene:EG11190
GeneID:947386
Associated reactions(s)
R_PTPATi (bigg2-eco41)Pantetheine-phosphate adenylyltransferase
b3634

GeneMatch: 1711 --> b0242 (top)
Matching Gene Information: b0242
functionenzyme; Amino acid biosynthesis: Proline
GO_componentGO:0005737 - cytoplasm
gene_synonymECK0243; JW0232; pro
EC_number2.7.2.11
productgamma-glutamate kinase
GO_processGO:0006561 - proline biosynthetic process
experimentN-terminus verified by Edman degradation: PMID 6089111
protein_idNP_414777.1
geneproB
db_xrefGI:16128228
ASAP:ABE-0000830
UniProtKB/Swiss-Prot:P0A7B5
ECOCYC:EG10768
EcoGene:EG10768
GeneID:946425
Associated reactions(s)
R_GLU5K (bigg2-eco41)Glutamate 5-kinase
b0242

GeneMatch: 0264 --> b1363 (top)
Matching Gene Information: b1363
functiontransport; Transport of small molecules: Cations; Phage or Prophage Related
GO_componentGO:0019866 - organelle inner membrane;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK1362; JW1358
productRac prophage; potassium transporter subunit
genetrkG
protein_idNP_415881.1
db_xrefGI:16129324
ASAP:ABE-0004567
UniProtKB/Swiss-Prot:P23849
ECOCYC:EG11020
EcoGene:EG11020
GeneID:945932
Associated reactions(s)
R_Kt2r (bigg2-eco41)Potassium reversible transport via proton symport
((b1363 or b3849))

GeneMatch: 0603 --> b0273 (top)
Matching Gene Information: b0273
functionenzyme; Amino acid biosynthesis: Arginine; Phage or Prophage Related
GO_componentGO:0005737 - cytoplasm
gene_synonymArg5; argD; ECK0274; JW0266
EC_number2.1.3.3
noteornithine carbamoyltransferase 2, chain F
GO_processGO:0006526 - arginine biosynthetic process
geneargF
productornithine carbamoyltransferase 2, chain F; CP4-6 prophage
protein_idNP_414807.1
db_xrefGI:16128258
ASAP:ABE-0000939
UniProtKB/Swiss-Prot:P06960
ECOCYC:EG10067
EcoGene:EG10067
GeneID:944844
Associated reactions(s)
R_OCBT (bigg2-eco41)Ornithine carbamoyltransferase
((b4254 or b0273))

GeneMatch: 1012 --> b3417 (top)
Matching Gene Information: b3417
functionenzyme; Degradation of small molecules: Carbon compounds
gene_synonymblu; ECK3404; JW5689; malA
EC_number2.4.1.1
productmaltodextrin phosphorylase
GO_processGO:0016052 - carbohydrate catabolic process;
GO:0000272 - polysaccharide catabolic process
genemalP
protein_idYP_026218.1
db_xrefGI:49176351
ASAP:ABE-0011154
UniProtKB/Swiss-Prot:P00490
ECOCYC:EG10560
EcoGene:EG10560
GeneID:947922
Associated reactions(s)
R_GLCP (bigg2-eco41)Glycogen phosphorylase
((b3428 or b3417))
R_MLTP3 (bigg2-eco41)Maltodextrin phosphorylase (maltoheptaose)
b3417
R_MLTP1 (bigg2-eco41)Maltodextrin phosphorylase (maltopentaose)
b3417
R_MLTP2 (bigg2-eco41)Maltodextrin phosphorylase (maltohexaose)
b3417

GeneMatch: 1164 --> b0810 (top)
Matching Gene Information: b0810
functiontransport; Transport of small molecules: Amino acids, amines
GO_componentGO:0019866 - organelle inner membrane;
GO:0009274 - peptidoglycan-based cell wall
gene_synonymECK0799; JW0795
noteglutamine high-affinity transport system; membrane component
GO_processGO:0006542 - glutamine biosynthetic process
geneglnP
productglutamine transporter subunit
protein_idNP_415331.1
db_xrefGI:16128778
ASAP:ABE-0002766
UniProtKB/Swiss-Prot:P0AEQ6
ECOCYC:EG10388
EcoGene:EG10388
GeneID:945621
Associated reactions(s)
R_GLNabc (bigg2-eco41)L-glutamine transport via ABC system
((b0810 and b0811 and b0809))

 

Generated by MetaDraft 0.9.3 © MetaToolkit.