Data from: Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release
Creators
- 1. The University of Texas Health Science Center at San Antonio
- 2. Heidelberg University
- 3. Johns Hopkins University
Description
This collection of data sets was obtained during a study of the effect of acute ethanol intoxication on vigilance-dependent astroglia network activation in mice. The main findings have been that ethanol inhibits astroglia activation by inhibiting vigilance-dependent norepinephrine release. This leads to a failure of activation of alpha1A-adrenergic receptors on astroglia. Further, this study has revealed that ethanol inhibition of cerebellar Bergmann glia Ca2+ activation does not account for ataxic motor behavior, but may rather contribute to cognitive deficits.
Notes
All data are contained in one Excel file. The data of individual figures or supplementary figures have been organized into corresponding tabs. Within each tab the data are organized according to figure sub-panels. Annotations allow clear association of raw data with individual figure sub-panels (each dot within data plots is accounted for by its value in the Excel file). Statistical test results have been included with a mentioning of the type of test used.
Funding provided by: National Institute on Alcohol Abuse and Alcoholism
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000027
Award Number: R01AA025128
Funding provided by: National Institute of Mental Health
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000025
Award Number: R01MH113780
Funding provided by: National Institute of Mental Health
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100000025
Award Number: R01MH083728
Funding provided by: The Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/100012394
Award Number:
Funding provided by: Deutsche Forschungsgemeinschaft
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100001659
Award Number: A09N/SFB1158
Funding provided by: Chica and Heinz Schaller Research Foundation
Crossref Funder Registry ID: http://dx.doi.org/10.13039/501100012284
Award Number:
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