This dataset gathers original acquisitions associated with the following paper:
  Lajous H. et al. (2020) T2 Mapping from Super-Resolution-Reconstructed Clinical Fast Spin Echo Magnetic Resonance Acquisitions.
  In: Martel A.L. et al. (eds) Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020.
  Lecture Notes in Computer Science, vol 12262. Springer, Cham. https://doi.org/10.1007/978-3-030-59713-9_12

Copyright (c) - All rights reserved. Medical Image Analysis Laboratory - Department of Radiology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland. 2020.



This dataset provides various acquisitions for T2 mapping of the MnCl2 array of the NIST phantom [1] at 1.5T. Data were acquired on a MAGNETOM Sola (Siemens Healthcare, Erlangen, Germany), with an 18-channel body coil and a 32-channel spine coil (12 elements used).
It is composed of DICOM images from:
i) Gold-standard single-echo spin echo (SE) sequences acquired at variable TE:
 - TR: 5000 ms;
 - 25 TEs sampled from 10 to 400 ms;
 - Voxel size: 0.98 x 0.98 x 6.0 mm3;
 - Slice number: 1 slice;
 - Orientation: coronal;
 - Total acquisition time higher than 7 hours (17.47 minutes per TE).

ii) Alternative reference multi-echo spin echo (MESE) acquisitions:
 - TR: 5000 ms;
 - 32 TEs equally sampled from 13 to 416 ms;
 - Voxel size: 0.98 x 0.98 x 6.0 mm3;
 - Slice number: 1 slice;
 - Orientation: coronal;
 - Total acquisition time: 16.05 minutes.
Please note that the number 'k' at the end of the name of each MESE image corresponds to the 'k'-th echo (k = 1 <-> TE = 13 ms; k = 2 <-> TE = 26 ms; ... ; k = 32 <-> TE = 416 ms).

iii) Half-Fourier Acquisition Single-shot Turbo spin Echo (HASTE) images at variable TE in three orthogonal orientations:
 - TR: 1200 ms;
 - 6 TEs: 90 ms, 131 ms, 175 ms, 216 ms, 257 ms, 298 ms;
 - Excitation/refocusing pulse flip angles: 90°/180°;
 - Voxel size: 1.125 x 1.125 x 3.000 mm3;
 - Interslice gap: 10%;
 - Field-of-view: 360 x 360 mm2;
 - Slice number: 23 slices;
 - Total acquisition time of about 9 minutes (28 seconds per TE).
Please note that the field-of-view does not cover the entire MnCl2 array of the NIST phantom in the axial and sagittal orientations, but focuses on three regions of interest in this layer ((T2-3) T2 = 428.3 ms, T1 = 1923 ms; (T2-4) T2 = 258.4 ms, T1 = 1489 ms; (T2-5) T2 = 186.1 ms, T1 = 1245 ms) for subsequent super-resolution reconstruction of these regions while keeping the same protocol (including the field-of-view) as the one used for fetal brain examination in clinical routine.

These acquisitions were repeated independently on three different days during the month of January 2020.

The dataset is organized as follows: 3 folders (Day_1, Day_2, Day_3) and a ReadMe.txt. The images acquired on a same day are stored in one of this folder and divided into subfolders according to the sequence used (3 subfolders per day: SE, MESE and HASTE). The HASTE subfolder is again subdivided into 3 for axial, coronal and sagittal acquisitions.
The name of all images begins with 'HL-FetalBrain-T2mappingRepeat-NISTphantom-' and mentions the acquisition date (format: YYYYMMDD), the sequence name/type, the TE at which the image was acquired and the slice orientation. Additional relevant information may also be provided.

These data are made publicly available as a support for further reproducibility studies as well as for the validation of new T2 relaxometry strategies.

Works using any of these data should cite the following two references:
- Lajous H. et al. (2020) T2 Mapping from Super-Resolution-Reconstructed Clinical Fast Spin Echo Magnetic Resonance Acquisitions. In: Martel A.L. et al. (eds) Medical Image Computing and Computer Assisted Intervention – MICCAI 2020. MICCAI 2020. Lecture Notes in Computer Science, vol 12262. Springer, Cham. https://doi.org/10.1007/978-3-030-59713-9_12
- Lajous H., Ledoux J.B., Hilbert T., van Heeswijk R.B., Bach Cuadra M.: Dataset T2 Mapping from Super-Resolution-Reconstructed Clinical Fast Spin Echo Magnetic Resonance Acquisitions (2020). https://doi.org/10.5281/zenodo.3931812


Additional references:
  [1] Keenan K.E. et al.: Multi-site, multi-vendor comparison of T1 measurement using ISMRM/NIST system phantom. In: Proceedings of the 24th Annual Meeting of ISMRM, Singapore (2016). Program number 3290.