RESULTS
The initial research found 49 references. After the review, 14 articles meet the inclusion criteria set out in this review,13–25 figure 1.
In total, up to March 30, 2020, we found a total of 83 pregnant women infected with SARS-CoV-2 who comply with information on pregnancy and birth data, and in total 84 births were evaluated, table 1. All articles are about patients in China.
The maternal results show that the patients were, on average, 30 years old and a gestational age of 37 weeks; table 2. The most common symptom was fever, and 30% of pregnant women had lymphopenia on hospital admission. The diagnostic method used for pulmonary complication was computed tomography in 88% of patients, chest radiography was only used in one patient. Vaginal delivery only occurred in 11%, while the indication for caesarean section in 70% was caused by the presence of pulmonary disease due to the coronavirus. The most common obstetric complication was premature rupture of membranes, with 9.6%; table 2. The need for mechanical ventilatory support occurred in 3 patients (3.6%), and one of them was during pregnant. In pregnant women, the use of antivirals, corticosteroids, and drugs for the management of maternal pathology was little, except for antibiotics.
Preterm birth was observed in one out of 4 patients; table 3. Pneumonia was diagnosed in 13% of the newborns, possibly not associated with SARS-CoV-2. Four newborns were to SARS-CoV-2 quantitative RT-PCR, however, vertical transmission was not confirmed. There were two perinatal deaths, one intrauterine and the other after 9 days post-birth.
There were no maternal deaths among the 83 pregnant women diagnosed with SARS-CoV-19, however the evolution of a very complicated patient is unknown.