RESULTS
The initial research found 49 references. After the review, 14 articles
meet the inclusion criteria set out in this review,13–25 figure 1.
In total, up to March 30, 2020, we found a total of 83 pregnant women
infected with SARS-CoV-2 who comply with information on pregnancy and
birth data, and in total 84 births were evaluated, table 1. All articles
are about patients in China.
The maternal results show that the patients were, on average, 30 years
old and a gestational age of 37 weeks; table 2. The most common symptom
was fever, and 30% of pregnant women had lymphopenia on hospital
admission. The diagnostic method used for pulmonary complication was
computed tomography in 88% of patients, chest radiography was only used
in one patient. Vaginal delivery only occurred in 11%, while the
indication for caesarean section in 70% was caused by the presence of
pulmonary disease due to the coronavirus. The most common obstetric
complication was premature rupture of membranes, with 9.6%; table 2.
The need for mechanical ventilatory support occurred in 3 patients
(3.6%), and one of them was during pregnant. In pregnant women, the use
of antivirals, corticosteroids, and drugs for the management of maternal
pathology was little, except for antibiotics.
Preterm birth was observed in one out of 4 patients; table 3. Pneumonia
was diagnosed in 13% of the newborns, possibly not associated with
SARS-CoV-2. Four newborns were to SARS-CoV-2 quantitative RT-PCR,
however, vertical transmission was not confirmed. There were two
perinatal deaths, one intrauterine and the other after 9 days
post-birth.
There were no maternal deaths among the 83 pregnant women diagnosed with
SARS-CoV-19, however the evolution of a very complicated patient is
unknown.