hgnc_symbol,gene_name,ensembl_gene,entrez,uniprot,sources,n_sources,conserved_in_mouse,mouse_ortholog,mouse_perc_identity,conserved_in_zebrafish,gtex_top_tissue,gtex_top_tpm,gtex_max_tpm,hpa_rna_tissue_specificity,hpa_single_cell_specificity,string_degree,string_top_partners
A2M,alpha-2-macroglobulin,ENSG00000175899,2,P01023,GenAge,1,TRUE,A2m,72.3881,FALSE,Lung,3455.95,3455.95,Tissue enhanced,Cell type enhanced,19,IL1B(0.984)|APOE(0.975)|HSPA5(0.972)|MMP2(0.953)|IL6(0.95)
AAK1,AP2 associated kinase 1,ENSG00000115977,22848,Q2M2I8,CellAge,1,TRUE,Aak1,89.5942,TRUE,Brain_Cerebellar_Hemisphere,29,29,Tissue enhanced,Low cell type specificity,0,
ABCB1,ATP binding cassette subfamily B member 1,ENSG00000085563,5243,P08183,CellAge,1,TRUE,Abcb1a,87.2656,FALSE,Adrenal_Gland,155.95,155.95,Tissue enhanced,Cell type enhanced,2,STAT3(0.8)|MVP(0.76)
ABCC6,ATP binding cassette subfamily C member 6,ENSG00000275331,368,O95255,CellAge,1,FALSE,,,FALSE,,,,,,0,
ABI3,ABI family member 3,ENSG00000108798,51225,Q9P2A4,CellAge,1,TRUE,Abi3,84.9727,TRUE,Spleen,90.23,90.23,Tissue enhanced,Cell type enhanced,1,ABI3BP(0.998)
ABI3BP,ABI family member 3 binding protein,ENSG00000154175,25890,Q7Z7G0,CellAge,1,TRUE,Abi3bp,68.813,TRUE,Cells_Cultured_fibroblasts,98.37,98.37,Low tissue specificity,Cell type enhanced,1,ABI3(0.998)
ABL1,"ABL proto-oncogene 1, non-receptor tyrosine kinase",ENSG00000097007,25,P00519,GenAge,1,TRUE,Abl1,86.4602,TRUE,Colon_Sigmoid,166.08,166.08,Low tissue specificity,Low cell type specificity,54,GRB2(0.999)|SHC1(0.991)|ATM(0.988)|HSP90AA1(0.983)|STAT5B(0.983)
ACD,ACD shelterin complex subunit and telomerase recruitment factor,ENSG00000102977,65057,Q96AP0,Reactome,1,TRUE,Acd,59.1703,TRUE,Brain_Cerebellum,85.2,85.2,Low tissue specificity,Cell type enhanced,13,POT1(0.999)|TERF1(0.999)|TERF2(0.999)|TERF2IP(0.999)|TINF2(0.999)
ACER2,alkaline ceramidase 2,ENSG00000177076,340485,Q5QJU3,CellAge,1,TRUE,Acer2,93.0909,TRUE,Adipose_Subcutaneous,12.26,12.26,Group enriched,Cell type enhanced,2,ASAH1(0.978)|SPHK1(0.968)
ACKR1,atypical chemokine receptor 1 (Duffy blood group),ENSG00000213088,2532,Q16570,CellAge,1,TRUE,Ackr1,58.9286,FALSE,Adipose_Subcutaneous,321.95,321.95,Tissue enhanced,Cell type enriched,5,CXCL8(0.999)|CCL2(0.994)|CCL5(0.993)|CXCL1(0.993)|CD82(0.973)
ACLY,ATP citrate lyase,ENSG00000131473,47,P53396,CellAge,1,TRUE,Acly,97.1844,TRUE,Cells_Cultured_fibroblasts,160.69,160.69,Low tissue specificity,Cell type enhanced,10,FASN(0.994)|PCK1(0.959)|SDHC(0.95)|SREBF1(0.795)|G6PD(0.785)
ACVR1B,activin A receptor type 1B,ENSG00000135503,91,P36896,SenMayo,1,TRUE,Acvr1b,98.2178,TRUE,Skin_Sun_Exposed_Lower_leg,65.21,65.21,Low tissue specificity,Cell type enhanced,8,TGFBR1(0.988)|SMAD2(0.972)|SMAD3(0.936)|GDF11(0.932)|BMP4(0.865)
ADCK5,aarF domain containing kinase 5,ENSG00000285451,203054,Q3MIX3,CellAge,1,FALSE,,,FALSE,,,,,,0,
ADCY5,adenylate cyclase 5,ENSG00000173175,111,O95622,GenAge,1,TRUE,Adcy5,94.7661,TRUE,Esophagus_Gastroesophageal_Junction,129.67,129.67,Tissue enhanced,Cell type enhanced,7,RAPGEF4(0.955)|CNR1(0.922)|PRKCD(0.913)|PRKCA(0.878)|AKT1(0.737)
AGO1,argonaute RISC component 1,ENSG00000092847,26523,Q9UL18,Reactome,1,TRUE,Ago1,100,TRUE,Brain_Cerebellar_Hemisphere,18.14,18.14,Low tissue specificity,Cell type enhanced,27,AGO2(0.999)|DICER1(0.999)|TNRC6A(0.999)|TNRC6B(0.994)|AGO4(0.993)
AGO2,argonaute RISC catalytic component 2,ENSG00000123908,27161,Q9UKV8,CellAge,1,TRUE,Ago2,98.8359,TRUE,Uterus,21.8,21.8,Low tissue specificity,Cell type enhanced,43,AGO1(0.999)|DHX9(0.999)|DICER1(0.999)|TNRC6A(0.999)|TNRC6B(0.998)
AGO3,argonaute RISC catalytic component 3,ENSG00000126070,192669,Q9H9G7,Reactome,1,TRUE,Ago3,98.9535,TRUE,Pituitary,10.88,10.88,Low tissue specificity,Cell type enhanced,11,AGO2(0.997)|DICER1(0.991)|AGO1(0.988)|TNRC6A(0.987)|TNRC6C(0.972)
AGO4,argonaute RISC component 4,ENSG00000134698,192670,Q9HCK5,Reactome,1,TRUE,Ago4,98.8386,TRUE,Spleen,27.62,27.62,Low tissue specificity,Cell type enhanced,12,AGO1(0.993)|DICER1(0.99)|TNRC6A(0.99)|AGO2(0.988)|AGO3(0.966)
AGPAT2,1-acylglycerol-3-phosphate O-acyltransferase 2,ENSG00000169692,10555,O15120,GenAge,1,TRUE,Agpat2,76.9784,TRUE,Adipose_Visceral_Omentum,493.67,493.67,Tissue enhanced,Cell type enhanced,6,BSCL2(0.988)|CAV1(0.844)|CAVIN1(0.841)|ZMPSTE24(0.801)|LMNA(0.742)
AGR2,"anterior gradient 2, protein disulphide isomerase family member",ENSG00000106541,10551,O95994,CellAge,1,TRUE,Agr2,91.4286,TRUE,Stomach,255.5,255.5,Tissue enhanced,Cell type enhanced,2,FOXA1(0.85)|ESR1(0.772)
AGT,angiotensinogen,ENSG00000135744,183,P01019,CellAge,1,TRUE,Agt,60.5042,TRUE,Liver,1007.43,1007.43,Tissue enriched,Group enriched,34,AGTR1(0.999)|MME(0.957)|EDN1(0.953)|LPAR1(0.92)|LPAR3(0.91)
AGTR1,angiotensin II receptor type 1,ENSG00000144891,185,P30556,GenAge,1,TRUE,Agtr1a,94.429,TRUE,Adipose_Subcutaneous,70.24,70.24,Tissue enhanced,Cell type enhanced,9,AGT(0.999)|SERPINE1(0.953)|ARRB1(0.948)|EDN1(0.898)|CXCL8(0.782)
AHR,aryl hydrocarbon receptor,ENSG00000106546,196,P35869,CellAge,1,TRUE,Ahr,69.4576,TRUE,Nerve_Tibial,133.72,133.72,Low tissue specificity,Cell type enhanced,5,HSP90AB1(0.995)|HSP90AA1(0.992)|ESR1(0.906)|ARNTL(0.792)|RB1(0.727)
AIFM1,apoptosis inducing factor mitochondria associated 1,ENSG00000156709,9131,O95831,GenAge,1,TRUE,Aifm1,88.0914,TRUE,Adrenal_Gland,62.82,62.82,Low tissue specificity,Cell type enhanced,4,ENDOG(0.946)|BAX(0.929)|GSR(0.78)|H2AX(0.78)
AKAP4,A-kinase anchoring protein 4,ENSG00000147081,8852,Q5JQC9,CellAge,1,TRUE,Akap4,77.6347,FALSE,Testis,478.02,478.02,Tissue enriched,Cell type enriched,0,
AKR1B1,aldo-keto reductase family 1 member B,ENSG00000085662,231,P15121,CellAge,1,TRUE,Akr1b1,85.443,TRUE,Adrenal_Gland,3174.59,3174.59,Tissue enriched,Cell type enhanced,2,ALDH2(0.944)|HK3(0.83)
AKT1,AKT serine/threonine kinase 1,ENSG00000142208,207,P31749,CellAge|GenAge,2,TRUE,Akt1,98.3333,TRUE,Artery_Aorta,88.76,88.76,Low tissue specificity,Cell type enhanced,202,CDC42(0.999)|FOXO1(0.999)|HSP90AA1(0.999)|HSP90AB1(0.999)|MDM2(0.999)
AKT1S1,AKT1 substrate 1,ENSG00000204673,84335,Q96B36,CellAge,1,TRUE,Akt1s1,92.9688,TRUE,Cells_Cultured_fibroblasts,41.31,41.31,Low tissue specificity,Cell type enhanced,15,DEPTOR(0.999)|MTOR(0.999)|RPTOR(0.999)|AKT1(0.995)|RICTOR(0.993)
AKT3,AKT serine/threonine kinase 3,ENSG00000275199,10000,Q9Y243,CellAge,1,FALSE,,,FALSE,,,,,,45,PIK3CA(0.984)|PIK3R1(0.977)|FOXO1(0.966)|FOXO3(0.966)|MDM2(0.966)
AKTIP,AKT interacting protein,ENSG00000166971,64400,Q9H8T0,CellAge,1,TRUE,Aktip,96.2329,TRUE,Brain_Frontal_Cortex_BA9,54.4,54.4,Low tissue specificity,Cell type enhanced,2,TERF1(0.909)|AKT1(0.775)
ALDH2,aldehyde dehydrogenase 2 family member,ENSG00000111275,217,P05091,CellAge,1,TRUE,Aldh2,95.3578,TRUE,Liver,183.3,183.3,Tissue enhanced,Cell type enhanced,2,AKR1B1(0.944)|HMGA2(0.78)
ALDOA,"aldolase, fructose-bisphosphate A",ENSG00000149925,226,P04075,CellAge,1,TRUE,Aldoa,85.1675,TRUE,Muscle_Skeletal,3137.24,3137.24,Group enriched,Cell type enhanced,4,GAPDH(0.999)|ENO1(0.988)|G6PD(0.894)|HK3(0.858)
ALKBH3,"alkB homolog 3, alpha-ketoglutarate dependent dioxygenase",ENSG00000166199,221120,Q96Q83,CellAge,1,TRUE,Alkbh3,77.2727,TRUE,Cervix_Ectocervix,30.41,30.41,Low tissue specificity,Cell type enhanced,0,
ALOX15B,arachidonate 15-lipoxygenase type B,ENSG00000179593,247,O15296,CellAge,1,TRUE,Alox8,77.9586,FALSE,Vagina,70.08,70.08,Tissue enhanced,Cell type enhanced,3,PTGS2(0.941)|LOX(0.826)|PLA2G2A(0.747)
ANAPC1,anaphase promoting complex subunit 1,ENSG00000153107,64682,Q9H1A4,CellAge|Reactome,2,TRUE,Anapc1,92.3868,TRUE,Cells_EBV-transformed_lymphocytes,20.02,20.02,Low tissue specificity,Cell type enhanced,48,ANAPC10(0.999)|ANAPC11(0.999)|ANAPC16(0.999)|ANAPC2(0.999)|ANAPC4(0.999)
ANAPC10,anaphase promoting complex subunit 10,ENSG00000164162,10393,Q9UM13,Reactome,1,TRUE,Anapc10,99.4595,TRUE,Testis,12.14,12.14,Low tissue specificity,Cell type enhanced,49,ANAPC1(0.999)|ANAPC11(0.999)|ANAPC15(0.999)|ANAPC16(0.999)|ANAPC2(0.999)
ANAPC11,anaphase promoting complex subunit 11,ENSG00000141552,51529,Q9NYG5,Reactome,1,TRUE,Anapc11,98.8095,TRUE,Testis,109.38,109.38,Low tissue specificity,Cell type enhanced,41,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC2(0.999)|ANAPC4(0.999)|ANAPC5(0.999)
ANAPC15,anaphase promoting complex subunit 15,ENSG00000110200,25906,P60006,Reactome,1,TRUE,Anapc15,100,TRUE,Testis,22.56,22.56,Low tissue specificity,Cell type enhanced,41,ANAPC10(0.999)|ANAPC16(0.999)|ANAPC4(0.999)|ANAPC5(0.999)|CDC23(0.999)
ANAPC16,anaphase promoting complex subunit 16,ENSG00000166295,119504,Q96DE5,Reactome,1,TRUE,Anapc16,100,TRUE,Artery_Tibial,111.97,111.97,Low tissue specificity,Low cell type specificity,40,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC15(0.999)|ANAPC5(0.999)|ANAPC7(0.999)
ANAPC2,anaphase promoting complex subunit 2,ENSG00000176248,29882,Q9UJX6,Reactome,1,TRUE,Anapc2,94.4039,TRUE,Testis,83.05,83.05,Low tissue specificity,Cell type enhanced,47,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC4(0.999)|ANAPC5(0.999)
ANAPC4,anaphase promoting complex subunit 4,ENSG00000053900,29945,Q9UJX5,Reactome,1,TRUE,Anapc4,93.4406,TRUE,Fallopian_Tube,55.44,55.44,Low tissue specificity,Group enriched,48,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC15(0.999)|ANAPC2(0.999)
ANAPC5,anaphase promoting complex subunit 5,ENSG00000089053,51433,Q9UJX4,Reactome,1,TRUE,Anapc5,92.8477,TRUE,Cervix_Ectocervix,113.5,113.5,Low tissue specificity,Low cell type specificity,48,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC15(0.999)|ANAPC16(0.999)
ANAPC7,anaphase promoting complex subunit 7,ENSG00000196510,51434,Q9UJX3,Reactome,1,TRUE,Anapc7,98.2301,TRUE,Testis,52.16,52.16,Low tissue specificity,Cell type enhanced,42,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC16(0.999)|ANAPC2(0.999)|ANAPC4(0.999)
ANG,angiogenin,ENSG00000214274,283,P03950,SenMayo,1,TRUE,Ang,72.7891,FALSE,Liver,726.8,726.8,Tissue enriched,Cell type enriched,2,CXCL8(0.767)|RNASEL(0.74)
ANGPT1,angiopoietin 1,ENSG00000154188,284,Q15389,SenMayo,1,TRUE,Angpt1,97.3896,TRUE,Cells_Cultured_fibroblasts,49.2,49.2,Tissue enhanced,Cell type enhanced,20,KDR(0.994)|FLT1(0.984)|PDGFRB(0.916)|EGFR(0.85)|FGFR1(0.848)
ANGPTL4,angiopoietin like 4,ENSG00000167772,51129,Q9BY76,SenMayo,1,TRUE,Angptl4,75.8621,TRUE,Adipose_Subcutaneous,221.29,221.29,Tissue enhanced,Cell type enhanced,7,PPARG(0.875)|FSCN1(0.844)|PPARA(0.843)|EREG(0.764)|AREG(0.734)
ANLN,"anillin, actin binding protein",ENSG00000011426,54443,Q9NQW6,CellAge,1,TRUE,Anln,80.1601,TRUE,Brain_Spinal_cord_cervical_c-1,238.59,238.59,Tissue enriched,Cell type enhanced,24,RHOA(0.999)|RACGAP1(0.997)|ECT2(0.994)|KIF20A(0.949)|KIF11(0.947)
ANXA5,annexin A5,ENSG00000164111,308,P08758,CellAge,1,TRUE,Anxa5,92.8125,TRUE,Cells_Cultured_fibroblasts,1717.11,1717.11,Low tissue specificity,Cell type enhanced,21,GAPDH(0.943)|BCL2(0.899)|PARP1(0.874)|SOD1(0.846)|AKT1(0.821)
APEX1,apurinic/apyrimidinic endodeoxyribonuclease 1,ENSG00000100823,328,P27695,CellAge|GenAge,2,TRUE,Apex1,94.3396,TRUE,Cells_EBV-transformed_lymphocytes,271.61,271.61,Low tissue specificity,Low cell type specificity,29,FEN1(0.998)|POLB(0.998)|OGG1(0.986)|TXN(0.983)|PARP1(0.967)
APOC3,apolipoprotein C3,ENSG00000110245,345,P02656,GenAge,1,TRUE,Apoc3,61.6162,FALSE,Liver,7599.74,7599.74,Tissue enriched,Cell type enriched,8,APOE(0.999)|CETP(0.977)|TLR2(0.963)|PON1(0.933)|CLU(0.921)
APOE,apolipoprotein E,ENSG00000130203,348,P02649,GenAge,1,TRUE,Apoe,70.6625,TRUE,Adrenal_Gland,3543.25,3543.25,Tissue enhanced,Cell type enhanced,40,APOC3(0.999)|APP(0.999)|CLU(0.999)|LRP2(0.999)|MAPT(0.991)
APP,amyloid beta precursor protein,ENSG00000142192,351,P05067,GenAge,1,TRUE,App,94.8052,TRUE,Brain_Frontal_Cortex_BA9,561.14,561.14,Low tissue specificity,Cell type enhanced,63,APOE(0.999)|PSEN1(0.999)|CLU(0.998)|MAPT(0.995)|KAT5(0.993)
APTX,aprataxin,ENSG00000137074,54840,Q7Z2E3,GenAge,1,TRUE,Aptx,84.2105,TRUE,Testis,28.72,28.72,Low tissue specificity,Low cell type specificity,12,PARP1(0.917)|POLB(0.9)|APEX1(0.881)|OGG1(0.865)|FXN(0.841)
AR,androgen receptor,ENSG00000169083,367,P10275,CellAge|GenAge,2,TRUE,Ar,85.6522,TRUE,Cervix_Endocervix,41.07,41.07,Tissue enhanced,Cell type enhanced,61,HSP90AA1(0.999)|HSP90AB1(0.999)|MDM2(0.998)|CTNNB1(0.996)|FOXA1(0.996)
AREG,amphiregulin,ENSG00000109321,374,P15514,SenMayo,1,TRUE,Areg,69.0476,FALSE,Adipose_Visceral_Omentum,53.38,53.38,Tissue enhanced,Cell type enhanced,16,EGFR(0.999)|EGF(0.998)|EREG(0.998)|ERBB2(0.959)|ICAM1(0.947)
ARF1,ARF GTPase 1,ENSG00000143761,375,P84077,CellAge,1,TRUE,Arf1,100,TRUE,Artery_Aorta,423.29,423.29,Low tissue specificity,Cell type enhanced,6,PLD2(0.991)|PI4KB(0.981)|CDKN2A(0.94)|CDC42(0.849)|PRKD1(0.836)
ARG2,arginase 2,ENSG00000081181,384,P78540,CellAge,1,TRUE,Arg2,84.7458,TRUE,Prostate,55.88,55.88,Tissue enhanced,Cell type enhanced,2,IL10(0.811)|H3-4(0.747)
ARHGAP1,Rho GTPase activating protein 1,ENSG00000175220,392,Q07960,GenAge,1,TRUE,Arhgap1,96.5831,TRUE,Artery_Tibial,232.36,232.36,Low tissue specificity,Cell type enhanced,2,CDC42(0.999)|RHOA(0.999)
ARID1A,AT-rich interaction domain 1A,ENSG00000117713,8289,O14497,CellAge,1,TRUE,Arid1a,96.3239,TRUE,Cells_EBV-transformed_lymphocytes,51.54,51.54,Low tissue specificity,Low cell type specificity,34,ARID1B(0.999)|PBRM1(0.999)|SMARCA2(0.999)|SMARCA4(0.999)|SMARCB1(0.999)
ARID1B,AT-rich interaction domain 1B,ENSG00000049618,57492,Q8NFD5,CellAge,1,TRUE,Arid1b,88.027,TRUE,Ovary,15.67,15.67,Low tissue specificity,Low cell type specificity,11,ARID1A(0.999)|SMARCA2(0.999)|SMARCA4(0.999)|SMARCB1(0.999)|PBRM1(0.998)
ARID3A,AT-rich interaction domain 3A,ENSG00000116017,1820,Q99856,CellAge,1,TRUE,Arid3a,79.9325,TRUE,Cells_EBV-transformed_lymphocytes,44.16,44.16,Tissue enhanced,Cell type enhanced,1,TP53(0.929)
ARID4B,AT-rich interaction domain 4B,ENSG00000054267,51742,Q4LE39,CellAge,1,TRUE,Arid4b,89.6341,TRUE,Testis,33.59,33.59,Low tissue specificity,Cell type enhanced,16,SIN3A(0.997)|SIN3B(0.993)|HDAC1(0.99)|HDAC2(0.988)|RBBP4(0.987)
ARPC1B,actin related protein 2/3 complex subunit 1B,ENSG00000130429,10095,O15143,CellAge,1,TRUE,Arpc1b,87.6344,TRUE,Cells_EBV-transformed_lymphocytes,341.96,341.96,Tissue enhanced,Cell type enhanced,2,GMFG(0.927)|CDC42(0.792)
ARRB1,arrestin beta 1,ENSG00000137486,408,P49407,CellAge,1,TRUE,Arrb1,98.5646,TRUE,Lung,49.83,49.83,Low tissue specificity,Cell type enhanced,30,SRC(0.999)|MAPK3(0.991)|AKT1(0.99)|MDM2(0.99)|MAPK1(0.989)
ASAH1,N-acylsphingosine amidohydrolase 1,ENSG00000104763,427,Q13510,CellAge,1,TRUE,Asah1,79.2405,TRUE,Thyroid,183.93,183.93,Tissue enhanced,Cell type enhanced,2,SPHK1(0.98)|ACER2(0.978)
ASF1A,anti-silencing function 1A histone chaperone,ENSG00000111875,25842,Q9Y294,CellAge|Reactome,2,TRUE,Asf1a,99.5098,FALSE,Brain_Cerebellar_Hemisphere,27.02,27.02,Low tissue specificity,Cell type enhanced,18,HIRA(0.999)|UBN1(0.999)|CABIN1(0.998)|H3-4(0.997)|H3C1(0.991)
ASPH,aspartate beta-hydroxylase,ENSG00000198363,444,Q12797,CellAge,1,TRUE,Asph,81.5303,TRUE,Cells_Cultured_fibroblasts,90.68,90.68,Tissue enhanced,Cell type enhanced,0,
ASXL2,ASXL transcriptional regulator 2,ENSG00000143970,55252,Q76L83,CellAge,1,TRUE,Asxl2,77.561,TRUE,Testis,15.2,15.2,Low tissue specificity,Low cell type specificity,9,BAP1(0.999)|OGT(0.937)|EZH2(0.857)|SUZ12(0.756)|DNMT3A(0.735)
ATF2,activating transcription factor 2,ENSG00000115966,1386,P15336,GenAge,1,TRUE,Atf2,95.6436,TRUE,Brain_Cerebellar_Hemisphere,48.25,48.25,Low tissue specificity,Low cell type specificity,37,JUN(0.999)|MAPK14(0.998)|MAPK8(0.998)|MAPK11(0.993)|CREBBP(0.992)
ATF3,activating transcription factor 3,ENSG00000162772,467,P18847,CellAge,1,TRUE,Atf3,95.0276,TRUE,Adipose_Visceral_Omentum,139.79,139.79,Low tissue specificity,Cell type enhanced,28,JUN(0.999)|FOS(0.994)|JUND(0.994)|DDIT3(0.988)|SMAD3(0.988)
ATF6,activating transcription factor 6,ENSG00000118217,22926,P18850,CellAge,1,TRUE,Atf6,85.0746,TRUE,Artery_Tibial,24.33,24.33,Low tissue specificity,Cell type enhanced,13,HSPA5(0.999)|DDIT3(0.989)|EIF2AK3(0.978)|CALR(0.933)|CEBPB(0.929)
ATF7IP,activating transcription factor 7 interacting protein,ENSG00000171681,55729,Q6VMQ6,CellAge,1,TRUE,Atf7ip,75.2756,TRUE,Testis,23.2,23.2,Low tissue specificity,Cell type enhanced,4,SUMO2(0.979)|SP1(0.799)|H3-4(0.741)|SUMO1(0.741)
ATG10,autophagy related 10,ENSG00000152348,83734,Q9H0Y0,CellAge,1,TRUE,Atg10,78.6364,TRUE,Testis,7.22,7.22,Low tissue specificity,Cell type enhanced,8,ATG12(0.999)|ATG7(0.999)|ATG5(0.998)|ATG16L1(0.973)|ATG4D(0.848)
ATG12,autophagy related 12,ENSG00000145782,9140,O94817,CellAge,1,TRUE,Atg12,88.5714,TRUE,Cells_Cultured_fibroblasts,26.43,26.43,Low tissue specificity,Low cell type specificity,20,ATG10(0.999)|ATG16L1(0.999)|ATG5(0.999)|ATG7(0.999)|MAVS(0.999)
ATG16L1,autophagy related 16 like 1,ENSG00000281089,55054,Q676U5,CellAge,1,FALSE,,,FALSE,,,,,,14,ATG12(0.999)|ATG5(0.999)|ATG7(0.995)|WIPI1(0.99)|ATG10(0.973)
ATG4D,autophagy related 4D cysteine peptidase,ENSG00000130734,84971,Q86TL0,CellAge,1,TRUE,Atg4d,86.2869,TRUE,Testis,129.09,129.09,Low tissue specificity,Cell type enhanced,7,ATG7(0.916)|ATG5(0.898)|ATG12(0.885)|ATG10(0.848)|ATG16L1(0.806)
ATG5,autophagy related 5,ENSG00000057663,9474,Q9H1Y0,CellAge,1,TRUE,Atg5,96.7273,TRUE,Cervix_Ectocervix,19.52,19.52,Low tissue specificity,Cell type enhanced,28,ATG12(0.999)|ATG16L1(0.999)|ATG7(0.999)|MAVS(0.999)|ATG10(0.998)
ATG7,autophagy related 7,ENSG00000197548,10533,O95352,CellAge,1,TRUE,Atg7,91.8919,TRUE,Cells_Cultured_fibroblasts,17.21,17.21,Low tissue specificity,Cell type enhanced,25,ATG10(0.999)|ATG12(0.999)|ATG5(0.999)|FOXO1(0.998)|ATG16L1(0.995)
ATM,ATM serine/threonine kinase,ENSG00000149311,472,Q13315,CellAge|GenAge|Reactome,3,TRUE,Atm,83.7696,TRUE,Cells_EBV-transformed_lymphocytes,21.03,21.03,Low tissue specificity,Cell type enhanced,112,ATR(0.999)|BRCA1(0.999)|CHEK2(0.999)|MDC1(0.999)|MRE11(0.999)
ATP5PO,ATP synthase peripheral stalk subunit OSCP,ENSG00000241837,539,P48047,GenAge,1,TRUE,Atp5po,82.1596,TRUE,Heart_Left_Ventricle,374.97,374.97,Tissue enhanced,Cell type enhanced,8,COX5B(0.974)|ATP6V0C(0.971)|RPL11(0.872)|RPS9(0.8)|KDM6B(0.788)
ATP6V0A2,ATPase H+ transporting V0 subunit a2,ENSG00000185344,23545,Q9Y487,CellAge,1,TRUE,Atp6v0a2,91.5888,TRUE,Cells_EBV-transformed_lymphocytes,12.54,12.54,Low tissue specificity,Cell type enhanced,3,ATP6V0C(0.999)|PYCR1(0.809)|LOX(0.708)
ATP6V0C,ATPase H+ transporting V0 subunit c,ENSG00000185883,527,P27449,CellAge,1,TRUE,Atp6v0c,90.9677,TRUE,Brain_Cerebellar_Hemisphere,612.99,612.99,Low tissue specificity,Cell type enhanced,3,ATP6V0A2(0.999)|ATP5PO(0.971)|KDM6B(0.709)
ATR,ATR checkpoint kinase,ENSG00000175054,545,Q13535,CellAge|GenAge,2,TRUE,Atr,90.4312,TRUE,Adrenal_Gland,15.73,15.73,Low tissue specificity,Cell type enhanced,48,ATM(0.999)|CHEK1(0.999)|CHEK2(0.998)|BRCA1(0.996)|TOPBP1(0.996)
ATRAID,all-trans retinoic acid induced differentiation factor,ENSG00000138085,51374,Q6UW56,CellAge,1,TRUE,Atraid,77.2926,TRUE,Ovary,217.97,217.97,Low tissue specificity,Cell type enhanced,0,
ATRX,ATRX chromatin remodeler,ENSG00000085224,546,P46100,CellAge,1,TRUE,Atrx,83.7881,TRUE,Cells_EBV-transformed_lymphocytes,22.62,22.62,Low tissue specificity,Low cell type specificity,52,RAD51(0.999)|H3-4(0.995)|RAD52(0.993)|MECP2(0.981)|TP53(0.981)
ATXN10,ataxin 10,ENSG00000130638,25814,Q9UBB4,CellAge,1,TRUE,Atxn10,82.7368,TRUE,Cells_Cultured_fibroblasts,82.2,82.2,Low tissue specificity,Low cell type specificity,1,CACNA1A(0.899)
AURKA,aurora kinase A,ENSG00000087586,6790,O14965,CellAge,1,TRUE,Aurka,82.134,TRUE,Cells_EBV-transformed_lymphocytes,51.32,51.32,Tissue enhanced,Cell type enhanced,62,TPX2(0.999)|MYCN(0.998)|TACC3(0.998)|TP53(0.998)|PLK1(0.997)
AURKB,aurora kinase B,ENSG00000178999,9212,Q96GD4,CellAge,1,TRUE,Aurkb,84.3023,TRUE,Cells_EBV-transformed_lymphocytes,146.04,146.04,Tissue enhanced,Cell type enhanced,63,BIRC5(0.999)|BUB1B(0.999)|INCENP(0.999)|BUB1(0.997)|CDK1(0.997)
AXL,AXL receptor tyrosine kinase,ENSG00000167601,558,P30530,CellAge|SenMayo,2,TRUE,Axl,87.5839,TRUE,Cells_Cultured_fibroblasts,218.55,218.55,Low tissue specificity,Cell type enhanced,13,SRC(0.983)|SHC1(0.957)|GRB2(0.931)|PLCG2(0.918)|JAK2(0.915)
BAG3,BAG cochaperone 3,ENSG00000151929,9531,O95817,CellAge,1,TRUE,Bag3,84.8696,TRUE,Muscle_Skeletal,370.37,370.37,Tissue enhanced,Cell type enhanced,15,HSPA8(0.999)|STUB1(0.999)|BCL2(0.986)|HSPA1B(0.983)|HSPB1(0.98)
BAK1,BCL2 antagonist/killer 1,ENSG00000030110,578,Q16611,GenAge,1,TRUE,Bak1,76.7773,FALSE,Cells_EBV-transformed_lymphocytes,56.68,56.68,Low tissue specificity,Cell type enhanced,9,BCL2(0.999)|BCL2L1(0.999)|MCL1(0.998)|TP53(0.997)|BAX(0.996)
BAP1,BRCA1 associated deubiquitinase 1,ENSG00000163930,8314,Q92560,CellAge,1,TRUE,Bap1,93.4156,TRUE,Testis,230.6,230.6,Low tissue specificity,Cell type enhanced,29,ASXL2(0.999)|BRCA1(0.995)|OGT(0.978)|RBBP7(0.969)|EZH2(0.937)
BAX,"BCL2 associated X, apoptosis regulator",ENSG00000087088,581,Q07812,GenAge,1,TRUE,Bax,92.1875,TRUE,Cells_EBV-transformed_lymphocytes,212.86,212.86,Low tissue specificity,Cell type enhanced,19,BCL2(0.999)|BCL2L1(0.999)|MCL1(0.999)|BAK1(0.996)|TP53(0.994)
BAZ1A,bromodomain adjacent to zinc finger domain 1A,ENSG00000198604,11177,Q9NRL2,CellAge,1,TRUE,Baz1a,87.2751,TRUE,Cells_EBV-transformed_lymphocytes,53.03,53.03,Tissue enhanced,Cell type enhanced,5,RBBP4(0.943)|SMARCA2(0.862)|XRCC6(0.782)|SMARCA4(0.776)|H2BC21(0.707)
BCL11B,BCL11 transcription factor B,ENSG00000127152,64919,Q9C0K0,CellAge,1,TRUE,Bcl11b,85.906,TRUE,Skin_Sun_Exposed_Lower_leg,22.27,22.27,Group enriched,Cell type enhanced,14,SMARCA4(0.967)|ARID1B(0.966)|SMARCA2(0.951)|SUV39H1(0.948)|HDAC1(0.947)
BCL2,BCL2 apoptosis regulator,ENSG00000171791,596,P10415,CellAge|GenAge,2,TRUE,Bcl2,90.3766,TRUE,Cells_EBV-transformed_lymphocytes,49.69,49.69,Low tissue specificity,Cell type enhanced,130,BAK1(0.999)|BAX(0.999)|BCL2L1(0.999)|BECN1(0.999)|TP53(0.999)
BCL2L1,BCL2 like 1,ENSG00000171552,598,Q07817,CellAge,1,TRUE,Bcl2l1,97.8541,TRUE,Artery_Aorta,185.28,185.28,Low tissue specificity,Cell type enhanced,64,BAK1(0.999)|BAX(0.999)|BCL2(0.999)|BECN1(0.999)|TP53(0.999)
BCL2L2,BCL2 like 2,ENSG00000129473,599,Q92843,CellAge,1,TRUE,Bcl2l2,98.4456,FALSE,Colon_Sigmoid,158.09,158.09,Low tissue specificity,Cell type enriched,7,MCL1(0.988)|BECN1(0.987)|BAK1(0.959)|BCL2L1(0.933)|BAX(0.93)
BCL3,BCL3 transcription coactivator,ENSG00000069399,602,P20749,CellAge,1,TRUE,Bcl3,80.1762,TRUE,Lung,119.96,119.96,Tissue enhanced,Cell type enhanced,15,NFKB1(0.999)|NFKB2(0.999)|PIR(0.983)|RELB(0.959)|RELA(0.951)
BCL6,BCL6 transcription repressor,ENSG00000113916,604,P41182,CellAge,1,TRUE,Bcl6,94.7592,TRUE,Whole_Blood,333.82,333.82,Tissue enhanced,Cell type enriched,28,NCOR1(0.999)|NCOR2(0.999)|HDAC4(0.966)|TP53(0.957)|HDAC1(0.935)
BCLAF1,BCL2 associated transcription factor 1,ENSG00000029363,9774,Q9NYF8,CellAge,1,TRUE,Bclaf1,83.3696,FALSE,Ovary,74.47,74.47,Tissue enhanced,Low cell type specificity,7,EMD(0.971)|BCL2(0.945)|CCNB1(0.94)|H2AX(0.924)|BRCA1(0.79)
BDNF,brain derived neurotrophic factor,ENSG00000176697,627,P23560,GenAge,1,TRUE,Bdnf,97.5708,TRUE,Brain_Cerebellar_Hemisphere,5.85,5.85,Tissue enhanced,Cell type enhanced,49,NGFR(0.999)|MECP2(0.965)|CREB1(0.956)|MAPK3(0.942)|IGF1R(0.907)
BECN1,beclin 1,ENSG00000126581,8678,Q14457,CellAge,1,TRUE,Becn1,98,TRUE,Cells_Cultured_fibroblasts,70.45,70.45,Low tissue specificity,Low cell type specificity,52,BCL2(0.999)|BCL2L1(0.999)|HMGB1(0.999)|ITPR1(0.998)|MCL1(0.998)
BEX3,brain expressed X-linked 3,ENSG00000166681,27018,Q00994,SenMayo,1,TRUE,Bex3,93.0693,FALSE,Ovary,727.03,727.03,Tissue enhanced,Cell type enhanced,3,NGFR(0.991)|NGF(0.791)|CASP2(0.764)
BHLHE40,basic helix-loop-helix family member e40,ENSG00000134107,8553,O14503,CellAge,1,TRUE,Bhlhe40,90.2913,TRUE,Vagina,503.65,503.65,Low tissue specificity,Cell type enhanced,6,ARNTL(0.985)|CLOCK(0.939)|CSNK1E(0.865)|HDAC1(0.825)|CEBPB(0.78)
BIN1,bridging integrator 1,ENSG00000136717,274,O00499,CellAge,1,TRUE,Bin1,77.2344,TRUE,Muscle_Skeletal,953.18,953.18,Group enriched,Cell type enhanced,8,MYC(0.999)|CLU(0.955)|MAPT(0.941)|APOE(0.908)|GRB2(0.899)
BIRC5,baculoviral IAP repeat containing 5,ENSG00000089685,332,O15392,CellAge,1,TRUE,Birc5,82.3944,TRUE,Cells_EBV-transformed_lymphocytes,58.58,58.58,Tissue enhanced,Cell type enhanced,49,AURKB(0.999)|INCENP(0.999)|CDK1(0.997)|AURKA(0.993)|CCNB1(0.993)
BLK,"BLK proto-oncogene, Src family tyrosine kinase",ENSG00000136573,640,P51451,CellAge,1,TRUE,Blk,85.9406,TRUE,Cells_EBV-transformed_lymphocytes,103.76,103.76,Group enriched,Cell type enriched,2,STAT3(0.821)|EGFR(0.807)
BLM,BLM RecQ like helicase,ENSG00000197299,641,P54132,GenAge,1,TRUE,Blm,76.4291,TRUE,Cells_EBV-transformed_lymphocytes,20.08,20.08,Tissue enhanced,Cell type enhanced,42,MLH1(0.999)|RPA1(0.999)|TOP3A(0.999)|RAD51(0.998)|ATM(0.991)
BLVRA,biliverdin reductase A,ENSG00000106605,644,P53004,CellAge,1,TRUE,Blvra,82.0946,TRUE,Spleen,106.82,106.82,Low tissue specificity,Cell type enhanced,0,
BMAL1,basic helix-loop-helix ARNT like 1,ENSG00000133794,406,O00327,GenAge,1,TRUE,Bmal1,98.4026,TRUE,Ovary,35.51,35.51,Low tissue specificity,Cell type enhanced,0,
BMI1,"BMI1 proto-oncogene, polycomb ring finger",ENSG00000168283,648,P35226,CellAge|GenAge|Reactome,3,TRUE,Bmi1,96.6258,TRUE,Artery_Aorta,55.27,55.27,Low tissue specificity,Group enriched,71,CBX2(0.999)|CBX4(0.999)|CBX7(0.999)|CBX8(0.999)|EZH2(0.999)
BMP2,bone morphogenetic protein 2,ENSG00000125845,650,P12643,SenMayo,1,TRUE,Bmp2,91.1616,TRUE,Lung,24.11,24.11,Low tissue specificity,Cell type enhanced,21,BMPR2(0.999)|NOG(0.999)|BMP4(0.97)|BMP6(0.947)|FGF2(0.937)
BMP4,bone morphogenetic protein 4,ENSG00000125378,652,P12644,CellAge,1,TRUE,Bmp4,97.3039,TRUE,Vagina,25.9,25.9,Tissue enhanced,Cell type enriched,20,BMPR2(0.999)|NOG(0.999)|BMP2(0.97)|BMP6(0.966)|GATA4(0.925)
BMP6,bone morphogenetic protein 6,ENSG00000153162,654,P22004,SenMayo,1,TRUE,Bmp6,90.4483,TRUE,Adipose_Subcutaneous,29.74,29.74,Tissue enhanced,Cell type enhanced,6,BMPR2(0.999)|NOG(0.99)|BMP4(0.966)|BMP2(0.947)|SMAD5(0.798)
BMPR2,bone morphogenetic protein receptor type 2,ENSG00000204217,659,Q13873,CellAge,1,TRUE,Bmpr2,96.6281,TRUE,Lung,45.11,45.11,Low tissue specificity,Cell type enhanced,14,BMP2(0.999)|BMP4(0.999)|BMP6(0.999)|LIMK1(0.989)|SMAD5(0.984)
BMS1,BMS1 ribosome biogenesis factor,ENSG00000165733,9790,Q14692,CellAge,1,TRUE,Bms1,86.6615,TRUE,Cells_EBV-transformed_lymphocytes,34.16,34.16,Low tissue specificity,Low cell type specificity,10,PDCD11(0.999)|UTP6(0.999)|RPS9(0.994)|RPS14(0.989)|PES1(0.947)
BNIP3L,BCL2 interacting protein 3 like,ENSG00000104765,665,O60238,CellAge,1,TRUE,Bnip3l,96.8036,TRUE,Ovary,152.81,152.81,Low tissue specificity,Cell type enhanced,11,BCL2(0.995)|BCL2L1(0.951)|PINK1(0.876)|BECN1(0.873)|TP53(0.855)
BRAF,"B-Raf proto-oncogene, serine/threonine kinase",ENSG00000157764,673,P15056,CellAge,1,TRUE,Braf,92.0366,TRUE,Brain_Cerebellar_Hemisphere,27.58,27.58,Low tissue specificity,Cell type enhanced,41,HRAS(0.999)|MAP2K1(0.999)|NRAS(0.999)|RAF1(0.999)|YWHAZ(0.999)
BRCA1,BRCA1 DNA repair associated,ENSG00000012048,672,P38398,CellAge|GenAge,2,TRUE,Brca1,56.0923,FALSE,Cells_EBV-transformed_lymphocytes,19.77,19.77,Low tissue specificity,Cell type enhanced,191,ATM(0.999)|BRCA2(0.999)|BRIP1(0.999)|CHEK2(0.999)|ESR1(0.999)
BRCA2,BRCA2 DNA repair associated,ENSG00000139618,675,P51587,GenAge,1,TRUE,Brca2,57.1094,TRUE,Cells_EBV-transformed_lymphocytes,11.2,11.2,Tissue enhanced,Cell type enhanced,89,BRCA1(0.999)|FANCD2(0.999)|RAD51(0.999)|RAD51C(0.999)|BRIP1(0.998)
BRD4,bromodomain containing 4,ENSG00000141867,23476,O60885,CellAge,1,FALSE,,,FALSE,Uterus,39.4,39.4,Low tissue specificity,Cell type enhanced,47,RELA(0.999)|H3-4(0.991)|TP53(0.99)|EP300(0.988)|AR(0.969)
BRD7,bromodomain containing 7,ENSG00000166164,29117,Q9NPI1,CellAge,1,TRUE,Brd7,88.172,TRUE,Testis,41.93,41.93,Low tissue specificity,Low cell type specificity,16,PBRM1(0.999)|SMARCA4(0.999)|SMARCD1(0.999)|SMARCB1(0.998)|TP53(0.99)
BRIP1,BRCA1 interacting DNA helicase 1,ENSG00000136492,83990,Q9BX63,CellAge,1,TRUE,Brip1,69.8959,TRUE,Cells_EBV-transformed_lymphocytes,9.26,9.26,Tissue enhanced,Cell type enhanced,25,BRCA1(0.999)|MLH1(0.999)|TOPBP1(0.999)|BRCA2(0.998)|MRE11(0.998)
BSCL2,"BSCL2 lipid droplet biogenesis associated, seipin",ENSG00000168000,26580,Q96G97,GenAge,1,TRUE,Bscl2,82.0346,TRUE,Pituitary,297.66,297.66,Tissue enhanced,Cell type enhanced,5,AGPAT2(0.988)|CAVIN1(0.858)|CAV1(0.843)|LMNA(0.806)|ZMPSTE24(0.803)
BTG1,BTG anti-proliferation factor 1,ENSG00000133639,694,P62324,CellAge,1,TRUE,Btg1,100,TRUE,Skin_Sun_Exposed_Lower_leg,249.17,249.17,Tissue enhanced,Cell type enhanced,2,FOXO3(0.77)|PRMT1(0.712)
BTG2,BTG anti-proliferation factor 2,ENSG00000159388,7832,P78543,CellAge,1,TRUE,Btg2,93.6709,TRUE,Artery_Tibial,446.76,446.76,Low tissue specificity,Cell type enhanced,4,PRMT1(0.992)|TP53(0.888)|CNOT6L(0.84)|DUSP1(0.739)
BTG3,BTG anti-proliferation factor 3,ENSG00000154640,10950,Q14201,CellAge,1,TRUE,Btg3,93.6508,TRUE,Testis,69.48,69.48,Low tissue specificity,Cell type enriched,1,CNOT6L(0.719)
BUB1,BUB1 mitotic checkpoint serine/threonine kinase,ENSG00000169679,699,O43683,CellAge,1,TRUE,Bub1,71.9816,TRUE,Cells_EBV-transformed_lymphocytes,88.96,88.96,Group enriched,Cell type enhanced,63,BUB1B(0.999)|BUB3(0.999)|MAD2L1(0.999)|TTK(0.999)|CDK1(0.998)
BUB1B,BUB1 mitotic checkpoint serine/threonine kinase B,ENSG00000156970,701,O60566,CellAge|GenAge,2,TRUE,Bub1b,75.0476,TRUE,Cells_EBV-transformed_lymphocytes,71.08,71.08,Tissue enhanced,Cell type enhanced,76,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC2(0.999)|ANAPC4(0.999)|ANAPC7(0.999)
BUB3,BUB3 mitotic checkpoint protein,ENSG00000154473,9184,O43684,GenAge,1,TRUE,Bub3,99.0854,TRUE,Cells_EBV-transformed_lymphocytes,57.52,57.52,Low tissue specificity,Cell type enhanced,37,BUB1(0.999)|BUB1B(0.999)|CDC27(0.999)|MAD2L1(0.999)|ANAPC4(0.998)
C1QA,complement C1q A chain,ENSG00000173372,712,P02745,GenAge,1,TRUE,C1qa,71.0204,TRUE,Spleen,1383.12,1383.12,Tissue enhanced,Group enriched,1,CALR(0.943)
C3,complement C3,ENSG00000125730,718,P01024,SenMayo,1,TRUE,C3,77.0295,TRUE,Liver,1605.02,1605.02,Tissue enriched,Cell type enhanced,12,CD55(0.999)|ATG16L1(0.961)|APP(0.887)|CLU(0.803)|CXCL8(0.783)
CABIN1,calcineurin binding protein 1,ENSG00000099991,23523,Q9Y6J0,Reactome,1,TRUE,Cabin1,88.6937,TRUE,Brain_Cerebellum,71.75,71.75,Low tissue specificity,Low cell type specificity,5,HIRA(0.999)|UBN1(0.999)|ASF1A(0.998)|MEF2A(0.77)|TP53(0.721)
CACNA1A,calcium voltage-gated channel subunit alpha1 A,ENSG00000141837,773,O00555,GenAge,1,TRUE,Cacna1a,87.0311,TRUE,Brain_Cerebellum,304.84,304.84,Tissue enriched,Cell type enhanced,7,INS(0.926)|PRKCA(0.915)|ATXN10(0.899)|KCNA1(0.892)|TBP(0.777)
CALR,calreticulin,ENSG00000179218,811,P27797,CellAge,1,TRUE,Calr,94.2446,FALSE,Cells_Cultured_fibroblasts,2150.47,2150.47,Low tissue specificity,Cell type enhanced,22,HSPA5(0.995)|PPIB(0.987)|HSP90AB1(0.975)|HSP90AA1(0.968)|TLR4(0.953)
CAPNS1,calpain small subunit 1,ENSG00000126247,826,P04632,CellAge,1,TRUE,Capns1,94.7761,TRUE,Esophagus_Mucosa,381.85,381.85,Low tissue specificity,Cell type enhanced,0,
CARF,calcium responsive transcription factor,ENSG00000138380,79800,Q8N187,CellAge,1,TRUE,Carf,70.3448,TRUE,Nerve_Tibial,10.7,10.7,Low tissue specificity,Cell type enhanced,0,
CARM1,coactivator associated arginine methyltransferase 1,ENSG00000142453,10498,Q86X55,CellAge,1,TRUE,Carm1,97.8618,TRUE,Cells_EBV-transformed_lymphocytes,101.4,101.4,Tissue enhanced,Low cell type specificity,30,EP300(0.999)|H3C1(0.982)|PRMT1(0.982)|CREBBP(0.981)|ESR1(0.972)
CASP2,caspase 2,ENSG00000106144,835,P42575,CellAge,1,TRUE,Casp2,89.6018,TRUE,Cells_EBV-transformed_lymphocytes,37.19,37.19,Low tissue specificity,Cell type enhanced,7,TNFRSF1A(0.84)|TP53(0.794)|BCL2(0.78)|XIAP(0.775)|BCL2L1(0.77)
CAT,catalase,ENSG00000121691,847,P04040,GenAge,1,TRUE,Cat,89.3738,TRUE,Adipose_Subcutaneous,188.01,188.01,Tissue enhanced,Cell type enhanced,4,SOD1(0.92)|SOD2(0.908)|RGN(0.86)|PEX5(0.794)
CAV1,caveolin 1,ENSG00000105974,857,Q03135,CellAge,1,TRUE,Cav1,94.9438,TRUE,Cells_Cultured_fibroblasts,889.86,889.86,Low tissue specificity,Cell type enhanced,56,CAVIN1(0.999)|EGFR(0.999)|SRC(0.999)|ESR1(0.998)|DPP4(0.991)
CAVIN1,caveolae associated protein 1,ENSG00000177469,284119,Q6NZI2,CellAge,1,TRUE,Cavin1,93.0769,TRUE,Artery_Tibial,1136.09,1136.09,Low tissue specificity,Cell type enhanced,4,CAV1(0.999)|EGFR(0.885)|BSCL2(0.858)|AGPAT2(0.841)
CBS,cystathionine beta-synthase,ENSG00000160200,875,P35520,CellAge,1,TRUE,Cbs,84.029,TRUE,Liver,6.61,6.61,Tissue enhanced,Group enriched,5,CTH(0.999)|SELENBP1(0.848)|HTT(0.83)|GAPDH(0.761)|GNMT(0.712)
CBX2,chromobox 2,ENSG00000173894,84733,Q14781,Reactome,1,TRUE,Cbx2,81.5789,TRUE,Testis,27.65,27.65,Tissue enhanced,Cell type enhanced,43,BMI1(0.999)|PCGF2(0.999)|PHC1(0.999)|PHC2(0.999)|RING1(0.999)
CBX4,chromobox 4,ENSG00000141582,8535,O00257,Reactome,1,TRUE,Cbx4,88.75,TRUE,Skin_Not_Sun_Exposed_Suprapubic,42.41,42.41,Tissue enriched,Cell type enhanced,43,BMI1(0.999)|CBX8(0.999)|RING1(0.999)|RNF2(0.999)|CBX2(0.998)
CBX5,chromobox 5,ENSG00000094916,23468,P45973,CellAge,1,TRUE,Cbx5,97.9058,TRUE,Cells_EBV-transformed_lymphocytes,51.74,51.74,Tissue enhanced,Cell type enhanced,31,H3-4(0.999)|SUV39H1(0.999)|TRIM28(0.997)|H3C1(0.988)|H3-3A(0.959)
CBX6,chromobox 6,ENSG00000183741,23466,O95503,Reactome,1,TRUE,Cbx6,88.5922,TRUE,Brain_Frontal_Cortex_BA9,104.56,104.56,Tissue enhanced,Cell type enhanced,23,RING1(0.997)|BMI1(0.995)|RNF2(0.995)|CBX8(0.994)|PHC2(0.993)
CBX7,chromobox 7,ENSG00000100307,23492,O95931,CellAge,1,TRUE,Cbx7,88.4462,TRUE,Brain_Cerebellar_Hemisphere,253.84,253.84,Low tissue specificity,Cell type enhanced,45,BMI1(0.999)|RING1(0.999)|RNF2(0.999)|PCGF2(0.998)|EZH2(0.996)
CBX8,chromobox 8,ENSG00000141570,57332,Q9HC52,CellAge|Reactome,2,TRUE,Cbx8,87.1465,TRUE,Testis,11.94,11.94,Low tissue specificity,Cell type enhanced,44,BMI1(0.999)|CBX4(0.999)|PHC2(0.999)|RING1(0.999)|CBX2(0.998)
CCL1,C-C motif chemokine ligand 1,ENSG00000108702,6346,P22362,SenMayo,1,FALSE,,,TRUE,Testis,0.77,0.77,Group enriched,Group enriched,15,CCL5(0.945)|CXCR2(0.925)|CCL20(0.892)|CXCL10(0.878)|CXCL1(0.87)
CCL13,C-C motif chemokine ligand 13,ENSG00000181374,6357,Q99616,SenMayo,1,FALSE,,,TRUE,Nerve_Tibial,44.29,44.29,Tissue enhanced,Cell type enhanced,17,CXCL10(0.999)|CCL5(0.998)|CCL8(0.998)|CXCL12(0.998)|CCL24(0.996)
CCL16,C-C motif chemokine ligand 16,ENSG00000275152,6360,O15467,SenMayo,1,FALSE,,,FALSE,Liver,56.05,56.05,Tissue enriched,Cell type enriched,8,CCL5(0.998)|CXCR2(0.876)|CCL1(0.786)|CXCL10(0.746)|CXCL8(0.735)
CCL2,C-C motif chemokine ligand 2,ENSG00000108691,6347,P13500,CellAge|SenMayo,2,TRUE,Ccl2,52.5253,TRUE,Kidney_Medulla,104.86,104.86,Tissue enhanced,Cell type enhanced,81,CCL5(0.999)|CCL8(0.999)|CXCL8(0.999)|CCL26(0.998)|CXCR2(0.997)
CCL20,C-C motif chemokine ligand 20,ENSG00000115009,6364,P78556,SenMayo,1,TRUE,Ccl20,62.5,FALSE,Lung,7.8,7.8,Group enriched,Cell type enhanced,29,CCL5(0.999)|CXCL12(0.999)|CXCL1(0.981)|CCL2(0.979)|CCL3(0.97)
CCL24,C-C motif chemokine ligand 24,ENSG00000106178,6369,O00175,SenMayo,1,TRUE,Ccl24,57.9832,TRUE,Spleen,84.68,84.68,Group enriched,Cell type enhanced,8,CCL13(0.996)|CCL5(0.995)|CCL20(0.805)|CXCL10(0.8)|CXCR2(0.789)
CCL26,C-C motif chemokine ligand 26,ENSG00000006606,10344,Q9Y258,SenMayo,1,FALSE,,,TRUE,Ovary,19.93,19.93,Group enriched,Cell type enhanced,11,CCL2(0.998)|CXCL10(0.998)|CXCL12(0.996)|CCL13(0.995)|CCL5(0.995)
CCL3,C-C motif chemokine ligand 3,ENSG00000277632,6348,P10147,SenMayo,1,TRUE,Ccl3,76.087,TRUE,Cells_EBV-transformed_lymphocytes,462.73,462.73,Tissue enhanced,Cell type enhanced,34,CCL4(0.997)|TNF(0.988)|CXCR2(0.984)|CXCL8(0.977)|IL10(0.972)
CCL4,C-C motif chemokine ligand 4,ENSG00000275302,6351,P13236,SenMayo,1,TRUE,Ccl4,76.087,TRUE,Cells_EBV-transformed_lymphocytes,199.9,199.9,Tissue enhanced,Cell type enhanced,31,CCL3(0.997)|CXCL8(0.988)|CXCR2(0.977)|TNF(0.967)|CXCL10(0.959)
CCL5,C-C motif chemokine ligand 5,ENSG00000271503,6352,P13501,SenMayo,1,TRUE,Ccl5,80.2198,TRUE,Whole_Blood,221.11,221.11,Tissue enhanced,Group enriched,60,CCL2(0.999)|CCL20(0.999)|CXCL10(0.999)|CXCL12(0.999)|CXCL2(0.999)
CCL7,C-C motif chemokine ligand 7,ENSG00000108688,6354,P80098,SenMayo,1,TRUE,Ccl7,61.6162,TRUE,Cells_Cultured_fibroblasts,1.94,1.94,Tissue enriched,Group enriched,14,CXCR2(0.946)|CXCL8(0.907)|CCL2(0.883)|CXCL1(0.866)|CXCL10(0.833)
CCL8,C-C motif chemokine ligand 8,ENSG00000108700,6355,P80075,SenMayo,1,TRUE,Ccl12,60.6061,TRUE,Kidney_Medulla,9.39,9.39,Low tissue specificity,Group enriched,10,CCL2(0.999)|CXCL10(0.999)|CCL13(0.998)|CXCL2(0.998)|CXCL8(0.998)
CCN2,cellular communication network factor 2,ENSG00000118523,1490,P29279,CellAge|GenAge,2,TRUE,Ccn2,90.5444,TRUE,Artery_Aorta,2042.9,2042.9,Tissue enhanced,Cell type enhanced,35,TGFB1(0.969)|IGFBP7(0.921)|YAP1(0.899)|BMP2(0.849)|SMAD2(0.845)
CCN6,cellular communication network factor 6,ENSG00000112761,8838,O95389,CellAge,1,TRUE,Ccn6,78.2486,TRUE,Brain_Cerebellar_Hemisphere,5,5,Tissue enhanced,Group enriched,0,
CCNA1,cyclin A1,ENSG00000133101,8900,P78396,Reactome,1,TRUE,Ccna1,84.323,TRUE,Testis,119.57,119.57,Tissue enhanced,Cell type enriched,54,CDK1(0.999)|CDK2(0.999)|CDKN1A(0.999)|CDKN1B(0.999)|E2F1(0.999)
CCNA2,cyclin A2,ENSG00000145386,890,P20248,CellAge|GenAge|Reactome,3,TRUE,Ccna2,85.1852,TRUE,Cells_EBV-transformed_lymphocytes,104.55,104.55,Tissue enhanced,Cell type enhanced,116,ANAPC4(0.999)|CDC6(0.999)|CDK1(0.999)|CDK2(0.999)|CDK4(0.999)
CCNB1,cyclin B1,ENSG00000134057,891,P14635,CellAge,1,TRUE,Ccnb1,85.9122,TRUE,Cells_EBV-transformed_lymphocytes,126.88,126.88,Tissue enhanced,Cell type enhanced,103,ANAPC10(0.999)|ANAPC4(0.999)|CDC27(0.999)|CDK1(0.999)|CDK2(0.999)
CCND1,cyclin D1,ENSG00000110092,595,P24385,CellAge,1,TRUE,Ccnd1,93.8983,TRUE,Cells_Cultured_fibroblasts,202,202,Low tissue specificity,Cell type enhanced,116,CDK2(0.999)|CDK4(0.999)|CDK6(0.999)|CDKN1A(0.999)|CDKN1B(0.999)
CCND3,cyclin D3,ENSG00000112576,896,P30281,CellAge,1,TRUE,Ccnd3,94.5205,TRUE,Whole_Blood,133.52,133.52,Tissue enhanced,Cell type enhanced,26,CDK2(0.999)|CDK4(0.999)|CDK6(0.999)|CDKN1A(0.999)|CDKN1B(0.999)
CCNE1,cyclin E1,ENSG00000105173,898,P24864,Reactome,1,TRUE,Ccne1,78.7805,TRUE,Testis,28.54,28.54,Tissue enhanced,Cell type enriched,45,CDK2(0.999)|CDK4(0.999)|CDK6(0.999)|CDKN1A(0.999)|CDKN1B(0.999)
CCNE2,cyclin E2,ENSG00000175305,9134,O96020,Reactome,1,TRUE,Ccne2,92.3267,TRUE,Brain_Spinal_cord_cervical_c-1,11.09,11.09,Tissue enhanced,Cell type enhanced,34,CDK2(0.999)|CDKN1A(0.999)|CDKN1B(0.998)|CDK4(0.988)|CDC25A(0.984)
CD28,CD28 molecule,ENSG00000178562,940,P10747,CellAge,1,TRUE,Cd28,67.7273,FALSE,Spleen,6.06,6.06,Group enriched,Group enriched,25,GRB2(0.999)|CD40LG(0.998)|PIK3R1(0.993)|ICAM1(0.977)|IL2(0.965)
CD34,CD34 molecule,ENSG00000174059,947,P28906,CellAge,1,TRUE,Cd34,65.4545,TRUE,Adipose_Subcutaneous,115.77,115.77,Low tissue specificity,Cell type enhanced,32,BCL2(0.945)|PECAM1(0.94)|KITLG(0.934)|ENG(0.919)|KDR(0.906)
CD40LG,CD40 ligand,ENSG00000102245,959,P29965,CellAge,1,TRUE,Cd40lg,77.3946,FALSE,Spleen,5.51,5.51,Tissue enhanced,Cell type enhanced,27,CD28(0.998)|SELPLG(0.983)|TNF(0.942)|IL2(0.924)|IFNG(0.919)
CD55,CD55 molecule (Cromer blood group),ENSG00000196352,1604,P08174,SenMayo,1,TRUE,Cd55,45.1444,FALSE,Whole_Blood,181.94,181.94,Low tissue specificity,Cell type enhanced,2,C3(0.999)|ICAM1(0.916)
CD82,CD82 molecule,ENSG00000085117,3732,P27701,CellAge,1,TRUE,Cd82,76.4045,TRUE,Cells_EBV-transformed_lymphocytes,216,216,Low tissue specificity,Cell type enhanced,5,CD9(0.983)|ACKR1(0.973)|CTNNB1(0.762)|EGFR(0.738)|KAT5(0.706)
CD9,CD9 molecule,ENSG00000010278,928,P21926,SenMayo,1,TRUE,Cd9,89.0351,FALSE,Esophagus_Mucosa,448.05,448.05,Low tissue specificity,Cell type enhanced,16,CD82(0.983)|ICAM1(0.912)|DPP4(0.882)|EGFR(0.873)|HSP90AA1(0.871)
CDC16,cell division cycle 16,ENSG00000130177,8881,Q13042,Reactome,1,TRUE,Cdc16,95.4839,TRUE,Cervix_Endocervix,82.55,82.55,Low tissue specificity,Low cell type specificity,51,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC16(0.999)|ANAPC2(0.999)
CDC23,cell division cycle 23,ENSG00000094880,8697,Q9UJX2,Reactome,1,TRUE,Cdc23,95.4774,TRUE,Cells_EBV-transformed_lymphocytes,46.45,46.45,Low tissue specificity,Cell type enhanced,51,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC15(0.999)|ANAPC16(0.999)
CDC25A,cell division cycle 25A,ENSG00000164045,993,P30304,CellAge,1,TRUE,Cdc25a,84.542,TRUE,Testis,21.6,21.6,Tissue enhanced,Cell type enhanced,46,CHEK1(0.999)|CDK2(0.998)|CHEK2(0.998)|CCNB1(0.995)|CDK1(0.993)
CDC26,cell division cycle 26,ENSG00000176386,246184,Q8NHZ8,Reactome,1,TRUE,Cdc26,88.2353,TRUE,Cells_Cultured_fibroblasts,20.65,20.65,Low tissue specificity,Cell type enhanced,43,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC15(0.999)|ANAPC16(0.999)|ANAPC2(0.999)
CDC27,cell division cycle 27,ENSG00000004897,996,P30260,Reactome,1,TRUE,Cdc27,97.0874,TRUE,Cells_Cultured_fibroblasts,48.2,48.2,Low tissue specificity,Cell type enhanced,61,ANAPC1(0.999)|ANAPC10(0.999)|ANAPC11(0.999)|ANAPC16(0.999)|ANAPC2(0.999)
CDC42,cell division cycle 42,ENSG00000070831,998,P60953,GenAge,1,TRUE,Cdc42,100,TRUE,Cells_EBV-transformed_lymphocytes,227.04,227.04,Low tissue specificity,Cell type enhanced,55,AKT1(0.999)|ARHGAP1(0.999)|IQGAP2(0.999)|PAK4(0.999)|PIK3CB(0.999)
CDC45,cell division cycle 45,ENSG00000093009,8318,O75419,CellAge,1,TRUE,Cdc45,91.6961,TRUE,Testis,54.89,54.89,Group enriched,Cell type enhanced,57,MCM7(0.999)|TOPBP1(0.999)|TIMELESS(0.997)|CLSPN(0.995)|CDC6(0.994)
CDC6,cell division cycle 6,ENSG00000094804,990,Q99741,CellAge,1,TRUE,Cdc6,80,TRUE,Cells_EBV-transformed_lymphocytes,23.07,23.07,Tissue enhanced,Cell type enhanced,61,CCNA2(0.999)|CDK2(0.999)|MCM7(0.999)|ORC1(0.999)|CDC45(0.994)
CDC7,cell division cycle 7,ENSG00000097046,8317,O00311,CellAge,1,TRUE,Cdc7,79.0941,TRUE,Brain_Cerebellar_Hemisphere,26.14,26.14,Tissue enhanced,Cell type enriched,22,MCM7(0.999)|ATR(0.992)|CDC45(0.991)|CHEK2(0.988)|CDC6(0.977)
CDCA2,cell division cycle associated 2,ENSG00000184661,157313,Q69YH5,CellAge,1,TRUE,Cdca2,50.2444,TRUE,Testis,36.57,36.57,Group enriched,Cell type enhanced,17,BUB1B(0.916)|KIF11(0.904)|KIF20A(0.899)|BUB1(0.89)|KIF2C(0.885)
CDCA4,cell division cycle associated 4,ENSG00000170779,55038,Q9BXL8,CellAge,1,TRUE,Cdca4,73.029,TRUE,Cells_EBV-transformed_lymphocytes,55.9,55.9,Tissue enhanced,Cell type enhanced,1,PPP2R1A(0.761)
CDH1,cadherin 1,ENSG00000039068,999,P12830,CellAge,1,TRUE,Cdh1,81.2925,TRUE,Esophagus_Mucosa,140.35,140.35,Tissue enhanced,Cell type enhanced,66,CTNNB1(0.999)|EGFR(0.999)|SRC(0.988)|PSEN1(0.98)|ERBB2(0.97)
CDK1,cyclin dependent kinase 1,ENSG00000170312,983,P06493,CellAge|GenAge,2,TRUE,Cdk1,96.9697,TRUE,Cells_EBV-transformed_lymphocytes,108.39,108.39,Tissue enhanced,Cell type enhanced,125,BUB1B(0.999)|CCNA1(0.999)|CCNA2(0.999)|CCNB1(0.999)|ANAPC4(0.998)
CDK18,cyclin dependent kinase 18,ENSG00000117266,5129,Q07002,CellAge,1,TRUE,Cdk18,86.7089,TRUE,Brain_Spinal_cord_cervical_c-1,352.98,352.98,Group enriched,Cell type enriched,0,
CDK2,cyclin dependent kinase 2,ENSG00000123374,1017,P24941,CellAge|Reactome,2,TRUE,Cdk2,98.9933,TRUE,Cells_EBV-transformed_lymphocytes,64.47,64.47,Low tissue specificity,Group enriched,114,CCNA1(0.999)|CCNA2(0.999)|CCNB1(0.999)|CCND1(0.999)|CCND3(0.999)
CDK2AP1,cyclin dependent kinase 2 associated protein 1,ENSG00000111328,8099,O14519,CellAge,1,TRUE,Cdk2ap1rt,96.5217,TRUE,Brain_Spinal_cord_cervical_c-1,113.75,113.75,Tissue enhanced,Cell type enhanced,5,RBBP4(0.954)|RBBP7(0.948)|HDAC1(0.947)|HDAC2(0.887)|CHD5(0.747)
CDK4,cyclin dependent kinase 4,ENSG00000135446,1019,P11802,CellAge|Reactome,2,TRUE,Cdk4,94.7195,TRUE,Cells_Cultured_fibroblasts,154.33,154.33,Low tissue specificity,Cell type enhanced,80,CCNA2(0.999)|CCND1(0.999)|CCND3(0.999)|CCNE1(0.999)|CDK6(0.999)
CDK5,cyclin dependent kinase 5,ENSG00000164885,1020,Q00535,CellAge,1,TRUE,Cdk5,99.6575,TRUE,Brain_Frontal_Cortex_BA9,83.22,83.22,Tissue enhanced,Cell type enhanced,28,CDK5R1(0.999)|MAPT(0.999)|TP53(0.967)|CDKN1B(0.941)|CDK2(0.928)
CDK5R1,cyclin dependent kinase 5 regulatory subunit 1,ENSG00000176749,8851,Q15078,CellAge,1,TRUE,Cdk5r1,98.3713,TRUE,Brain_Cerebellar_Hemisphere,117.37,117.37,Tissue enriched,Cell type enhanced,13,CDK5(0.999)|MAPT(0.969)|TP53(0.798)|EGR1(0.796)|JUN(0.778)
CDK6,cyclin dependent kinase 6,ENSG00000105810,1021,Q00534,CellAge|Reactome,2,TRUE,Cdk6,96.319,TRUE,Cells_EBV-transformed_lymphocytes,32.3,32.3,Tissue enhanced,Cell type enhanced,44,CCNA2(0.999)|CCND1(0.999)|CCND3(0.999)|CCNE1(0.999)|CDK4(0.999)
CDK7,cyclin dependent kinase 7,ENSG00000134058,1022,P50613,GenAge,1,TRUE,Cdk7,94.5087,TRUE,Testis,50.21,50.21,Low tissue specificity,Cell type enhanced,36,ERCC2(0.999)|ERCC3(0.999)|GTF2H2(0.999)|CDK2(0.992)|TBP(0.983)
CDKN1A,cyclin dependent kinase inhibitor 1A,ENSG00000124762,1026,P38936,CellAge|GenAge|Reactome,3,TRUE,Cdkn1a,76.8293,TRUE,Artery_Aorta,417.83,417.83,Low tissue specificity,Cell type enhanced,89,CCNA1(0.999)|CCNA2(0.999)|CCND1(0.999)|CCND3(0.999)|CCNE1(0.999)
CDKN1B,cyclin dependent kinase inhibitor 1B,ENSG00000111276,1027,P46527,CellAge|Reactome,2,TRUE,Cdkn1b,87.3737,TRUE,Brain_Cerebellar_Hemisphere,193.42,193.42,Low tissue specificity,Cell type enhanced,62,CCNA1(0.999)|CCNA2(0.999)|CCND1(0.999)|CCND3(0.999)|CCNE1(0.999)
CDKN1C,cyclin dependent kinase inhibitor 1C,ENSG00000129757,1028,P49918,CellAge,1,TRUE,Cdkn1c,59.0164,TRUE,Ovary,273.19,273.19,Tissue enhanced,Cell type enhanced,29,CDK2(0.999)|CCNA2(0.998)|CDK6(0.995)|CCND1(0.994)|CDK4(0.994)
CDKN2A,cyclin dependent kinase inhibitor 2A,ENSG00000147889,1029,P42771,CellAge|GenAge|Reactome,3,TRUE,Cdkn2a,62.1795,FALSE,Pituitary,16.91,16.91,Tissue enhanced,Cell type enhanced,95,CDK4(0.999)|CDK6(0.999)|MDM2(0.999)|NPM1(0.999)|TP53(0.999)
CDKN2AIP,CDKN2A interacting protein,ENSG00000168564,55602,Q9NXV6,CellAge,1,TRUE,Cdkn2aip,84.4828,TRUE,Testis,38.91,38.91,Low tissue specificity,Cell type enhanced,1,CDKN2A(0.958)
CDKN2B,cyclin dependent kinase inhibitor 2B,ENSG00000147883,1030,P42772,CellAge|GenAge|Reactome,3,TRUE,Cdkn2b,81.8841,FALSE,Esophagus_Mucosa,56.72,56.72,Tissue enhanced,Cell type enhanced,18,CDK4(0.999)|CDK6(0.999)|CCND1(0.974)|MYC(0.966)|CDKN2A(0.951)
CDKN2C,cyclin dependent kinase inhibitor 2C,ENSG00000123080,1031,P42773,Reactome,1,TRUE,Cdkn2c,92.2619,TRUE,Artery_Tibial,34.03,34.03,Tissue enhanced,Cell type enhanced,12,CDK4(0.999)|CDK6(0.999)|CCND3(0.993)|CCND1(0.989)|TP53(0.957)
CDKN2D,cyclin dependent kinase inhibitor 2D,ENSG00000129355,1032,P55273,Reactome,1,TRUE,Cdkn2d,86.747,TRUE,Whole_Blood,217.24,217.24,Group enriched,Cell type enhanced,10,CDK4(0.999)|CDK6(0.999)|CCND3(0.978)|CCND1(0.952)|CDKN1B(0.925)
CEACAM1,CEA cell adhesion molecule 1,ENSG00000079385,634,P13688,CellAge,1,TRUE,Ceacam2,53.8023,FALSE,Esophagus_Mucosa,65.87,65.87,Tissue enhanced,Cell type enhanced,1,PTPN11(0.817)
CEBPA,CCAAT enhancer binding protein alpha,ENSG00000245848,1050,P49715,GenAge,1,TRUE,Cebpa,94.4134,TRUE,Skin_Not_Sun_Exposed_Suprapubic,132.82,132.82,Group enriched,Cell type enhanced,41,RUNX1(0.994)|CDK2(0.992)|CDK4(0.991)|PPARG(0.991)|CEBPB(0.99)
CEBPB,CCAAT enhancer binding protein beta,ENSG00000172216,1051,P17676,CellAge|GenAge|Reactome,3,TRUE,Cebpb,71.5942,TRUE,Whole_Blood,367.16,367.16,Low tissue specificity,Cell type enhanced,58,EP300(0.996)|DDIT3(0.994)|HDAC1(0.991)|CEBPA(0.99)|PPARG(0.989)
CEBPG,CCAAT enhancer binding protein gamma,ENSG00000153879,1054,P53567,CellAge,1,TRUE,Cebpg,91.3333,FALSE,Skin_Not_Sun_Exposed_Suprapubic,42.62,42.62,Low tissue specificity,Cell type enhanced,7,CEBPB(0.971)|DDIT3(0.949)|ATF3(0.834)|JUN(0.823)|FOS(0.773)
CENPA,centromere protein A,ENSG00000115163,1058,P49450,CellAge,1,TRUE,Cenpa,69.2857,TRUE,Cells_EBV-transformed_lymphocytes,32.24,32.24,Tissue enhanced,Cell type enhanced,60,HJURP(0.999)|H2AC18(0.998)|AURKB(0.997)|H2BC21(0.995)|CCNA2(0.99)
CETP,cholesteryl ester transfer protein,ENSG00000087237,1071,P11597,GenAge,1,FALSE,,,TRUE,Spleen,34.97,34.97,Group enriched,Cell type enriched,6,APOC3(0.977)|APOE(0.974)|PON1(0.968)|CLU(0.887)|HMGCR(0.781)
CHAF1B,chromatin assembly factor 1 subunit B,ENSG00000159259,8208,Q13112,CellAge,1,TRUE,Chaf1b,84.0787,TRUE,Cells_EBV-transformed_lymphocytes,12.97,12.97,Tissue enhanced,Cell type enhanced,9,RBBP4(0.999)|ASF1A(0.988)|PCNA(0.933)|H3C1(0.918)|CBX5(0.911)
CHD5,chromodomain helicase DNA binding protein 5,ENSG00000116254,26038,Q8TDI0,CellAge,1,TRUE,Chd5,93.0911,TRUE,Pituitary,97.47,97.47,Group enriched,Cell type enhanced,6,RBBP7(0.969)|HDAC1(0.962)|HDAC2(0.929)|RBBP4(0.919)|CDK2AP1(0.747)
CHEK1,checkpoint kinase 1,ENSG00000149554,1111,O14757,CellAge,1,TRUE,Chek1,93.0672,TRUE,Cells_EBV-transformed_lymphocytes,24.63,24.63,Tissue enhanced,Cell type enhanced,83,ATR(0.999)|CDC25A(0.999)|CLSPN(0.999)|ATM(0.998)|RAD51(0.998)
CHEK2,checkpoint kinase 2,ENSG00000183765,11200,O96017,CellAge|GenAge,2,TRUE,Chek2,83.2412,TRUE,Nerve_Tibial,14.61,14.61,Low tissue specificity,Cell type enhanced,54,ATM(0.999)|BRCA1(0.999)|TP53(0.999)|ATR(0.998)|CDC25A(0.998)
CHUK,component of inhibitor of nuclear factor kappa B kinase complex,ENSG00000213341,1147,O15111,CellAge,1,TRUE,Chuk,95.302,TRUE,Nerve_Tibial,13.81,13.81,Low tissue specificity,Cell type enhanced,55,IKBKB(0.999)|IKBKG(0.999)|NFKB1(0.999)|NFKBIA(0.999)|RELA(0.999)
CIP2A,cellular inhibitor of PP2A,ENSG00000163507,57650,Q8TCG1,CellAge,1,TRUE,Cip2a,83.6464,TRUE,Cells_EBV-transformed_lymphocytes,23.83,23.83,Low tissue specificity,Cell type enhanced,3,MYC(0.865)|PPP2R1A(0.863)|PLK1(0.705)
CISD2,CDGSH iron sulfur domain 2,ENSG00000145354,493856,Q8N5K1,GenAge,1,TRUE,Cisd2,96.2963,TRUE,Brain_Cerebellar_Hemisphere,28.12,28.12,Low tissue specificity,Cell type enhanced,2,BECN1(0.782)|BCL2(0.719)
CIT,citron rho-interacting serine/threonine kinase,ENSG00000122966,11113,O14578,CellAge,1,TRUE,Cit,96.0851,TRUE,Brain_Cortex,46.49,46.49,Tissue enhanced,Cell type enhanced,4,KIF20A(0.943)|ANLN(0.898)|RHOA(0.845)|CDKN1B(0.825)
CKAP2,cytoskeleton associated protein 2,ENSG00000136108,26586,Q8WWK9,CellAge,1,TRUE,Ckap2,59.9707,TRUE,Cells_EBV-transformed_lymphocytes,42.43,42.43,Tissue enhanced,Cell type enhanced,14,TOP2A(0.898)|BUB1B(0.886)|BUB1(0.879)|TTK(0.868)|KIF20A(0.861)
CKB,creatine kinase B,ENSG00000166165,1152,P12277,CellAge,1,TRUE,Ckb,96.5879,TRUE,Brain_Cerebellum,1768.49,1768.49,Tissue enhanced,Cell type enhanced,1,ENO1(0.736)
CLCA2,chloride channel accessory 2,ENSG00000137975,9635,Q9UQC9,CellAge,1,TRUE,Clca2,72.2163,FALSE,Esophagus_Mucosa,159.27,159.27,Tissue enhanced,Cell type enhanced,0,
CLOCK,clock circadian regulator,ENSG00000134852,9575,O15516,GenAge,1,TRUE,Clock,96.0993,TRUE,Brain_Cerebellar_Hemisphere,16.02,16.02,Low tissue specificity,Cell type enhanced,14,ARNTL(0.999)|SIRT1(0.999)|CSNK1E(0.994)|EP300(0.994)|CREBBP(0.976)
CLPP,caseinolytic mitochondrial matrix peptidase proteolytic subunit,ENSG00000125656,8192,Q16740,CellAge,1,TRUE,Clpp,85.5596,TRUE,Cells_EBV-transformed_lymphocytes,159.31,159.31,Low tissue specificity,Cell type enhanced,6,HSPD1(0.921)|HSPA9(0.829)|HTRA1(0.742)|TRAP1(0.725)|SPX(0.722)
CLSPN,claspin,ENSG00000092853,63967,Q9HAW4,CellAge,1,TRUE,Clspn,75.2054,FALSE,Cells_EBV-transformed_lymphocytes,13.35,13.35,Tissue enhanced,Cell type enhanced,26,CHEK1(0.999)|TIMELESS(0.999)|RPA1(0.998)|CDC45(0.995)|TOPBP1(0.995)
CLU,clusterin,ENSG00000120885,1191,P10909,CellAge|GenAge,2,TRUE,Clu,76.392,TRUE,Artery_Aorta,1603.78,1603.78,Tissue enhanced,Cell type enhanced,19,APOE(0.999)|APP(0.998)|PON1(0.996)|LRP2(0.994)|XRCC6(0.973)
CNOT6,CCR4-NOT transcription complex subunit 6,ENSG00000113300,57472,Q9ULM6,CellAge,1,TRUE,Cnot6,95.1526,TRUE,Brain_Cerebellar_Hemisphere,30.74,30.74,Low tissue specificity,Low cell type specificity,5,CNOT6L(0.999)|TNRC6C(0.819)|MMP7(0.788)|ZFP36(0.783)|TNRC6A(0.741)
CNOT6L,CCR4-NOT transcription complex subunit 6 like,ENSG00000138767,246175,Q96LI5,CellAge,1,TRUE,Cnot6l,97.1171,TRUE,Spleen,17.82,17.82,Low tissue specificity,Cell type enhanced,7,CNOT6(0.999)|BTG2(0.84)|MMP7(0.8)|TNRC6A(0.781)|TNRC6C(0.776)
CNR1,cannabinoid receptor 1,ENSG00000118432,1268,P21554,GenAge,1,TRUE,Cnr1,97.0339,TRUE,Brain_Cerebellar_Hemisphere,33.9,33.9,Tissue enhanced,Cell type enhanced,4,ADCY5(0.922)|BDNF(0.784)|TRPV1(0.781)|ARRB1(0.757)
COQ7,"coenzyme Q7, hydroxylase",ENSG00000167186,10229,Q99807,GenAge,1,TRUE,Coq7,79.7235,TRUE,Ovary,20.78,20.78,Low tissue specificity,Cell type enhanced,1,IMMT(0.816)
COX5B,cytochrome c oxidase subunit 5B,ENSG00000135940,1329,P10606,CellAge,1,TRUE,Cox5b,84.4961,TRUE,Heart_Left_Ventricle,467.4,467.4,Tissue enhanced,Cell type enhanced,6,MT-CO1(0.999)|ATP5PO(0.974)|HSPA9(0.925)|SDHC(0.886)|ATG5(0.723)
CPEB1,cytoplasmic polyadenylation element binding protein 1,ENSG00000214575,64506,Q9BZB8,CellAge,1,TRUE,Cpeb1,90.3061,TRUE,Testis,27.61,27.61,Tissue enhanced,Cell type enhanced,8,AURKA(0.955)|EIF4E(0.946)|CDK1(0.938)|PLK1(0.933)|FXR1(0.894)
CPT1C,carnitine palmitoyltransferase 1C,ENSG00000169169,126129,Q8TCG5,CellAge,1,TRUE,Cpt1c,83.3126,TRUE,Brain_Cerebellum,79.3,79.3,Tissue enhanced,Cell type enhanced,2,UCP3(0.81)|UCP2(0.72)
CREB1,cAMP responsive element binding protein 1,ENSG00000118260,1385,P16220,GenAge,1,TRUE,Creb1,99.6942,TRUE,Cells_EBV-transformed_lymphocytes,20.64,20.64,Low tissue specificity,Cell type enhanced,76,CREBBP(0.999)|EP300(0.999)|FOS(0.998)|JUN(0.998)|TP53(0.998)
CREBBP,CREB binding lysine acetyltransferase,ENSG00000005339,1387,Q92793,GenAge,1,TRUE,Crebbp,95.864,TRUE,Uterus,53.41,53.41,Low tissue specificity,Cell type enhanced,116,CREB1(0.999)|CTNNB1(0.999)|EP300(0.999)|HIF1A(0.999)|IRF3(0.999)
CREG1,cellular repressor of E1A stimulated genes 1,ENSG00000143162,8804,O75629,CellAge,1,TRUE,Creg1,76.8182,TRUE,Artery_Coronary,166.2,166.2,Low tissue specificity,Cell type enhanced,0,
CRISPLD2,cysteine rich secretory protein LCCL domain containing 2,ENSG00000103196,83716,Q9H0B8,CellAge,1,TRUE,Crispld2,77.0624,TRUE,Fallopian_Tube,175.16,175.16,Low tissue specificity,Cell type enhanced,0,
CSF1,colony stimulating factor 1,ENSG00000184371,1435,P09603,SenMayo,1,TRUE,Csf1,70.3971,TRUE,Cells_Cultured_fibroblasts,151.49,151.49,Low tissue specificity,Cell type enhanced,40,CSF2(0.964)|EGF(0.942)|EGFR(0.941)|SRC(0.91)|PDGFRB(0.909)
CSF2,colony stimulating factor 2,ENSG00000164400,1437,P04141,SenMayo,1,TRUE,Csf2,54.1667,FALSE,Lung,1.16,1.16,Tissue enhanced,Cell type enhanced,54,CSF2RB(0.999)|IL1B(0.998)|IL1A(0.997)|IL2(0.997)|IFNG(0.984)
CSF2RB,colony stimulating factor 2 receptor subunit beta,ENSG00000100368,1439,P32927,SenMayo,1,TRUE,Csf2rb,56.1873,FALSE,Whole_Blood,67.54,67.54,Tissue enhanced,Cell type enriched,18,CSF2(0.999)|JAK2(0.992)|EPOR(0.985)|HRAS(0.901)|NRAS(0.901)
CSNK1A1,casein kinase 1 alpha 1,ENSG00000113712,1452,P48729,CellAge,1,TRUE,Csnk1a1,99.7033,TRUE,Esophagus_Mucosa,105.94,105.94,Low tissue specificity,Low cell type specificity,12,CTNNB1(0.999)|GSK3B(0.999)|GSK3A(0.991)|MDM4(0.971)|MDM2(0.961)
CSNK1E,casein kinase 1 epsilon,ENSG00000213923,1454,P49674,GenAge,1,TRUE,Csnk1e,98.7981,TRUE,Ovary,112.94,112.94,Low tissue specificity,Cell type enhanced,16,ARNTL(0.997)|CLOCK(0.994)|GSK3B(0.989)|FOXO1(0.912)|FOXO3(0.912)
CSNK2A1,casein kinase 2 alpha 1,ENSG00000101266,1457,P68400,CellAge,1,TRUE,Csnk2a1,98.7212,TRUE,Cells_EBV-transformed_lymphocytes,73.2,73.2,Low tissue specificity,Low cell type specificity,27,OGT(0.982)|HDAC2(0.972)|PTEN(0.971)|HDAC1(0.961)|TP53(0.959)
CST4,cystatin S,ENSG00000101441,1472,P01036,SenMayo,1,FALSE,,,TRUE,Thyroid,1.02,1.02,Tissue enriched,Cell type enriched,1,CTSB(0.783)
CTF1,cardiotrophin 1,ENSG00000150281,1489,Q16619,GenAge,1,TRUE,Ctf1,79.1045,FALSE,Uterus,42.85,42.85,Low tissue specificity,Cell type enhanced,4,IL6ST(0.98)|PIR(0.91)|IL6(0.732)|JAK2(0.7)
CTH,cystathionine gamma-lyase,ENSG00000116761,1491,P32929,CellAge,1,TRUE,Cth,83.9506,TRUE,Liver,44.94,44.94,Tissue enriched,Cell type enhanced,6,CBS(0.999)|GCLC(0.906)|MVK(0.902)|GCLM(0.882)|GGCT(0.806)
CTNNAL1,catenin alpha like 1,ENSG00000119326,8727,Q9UBT7,CellAge,1,TRUE,Ctnnal1,87.3297,TRUE,Adrenal_Gland,235.86,235.86,Tissue enhanced,Cell type enhanced,0,
CTNNB1,catenin beta 1,ENSG00000168036,1499,P35222,CellAge|GenAge|SenMayo,3,TRUE,Ctnnb1,99.872,TRUE,Cervix_Endocervix,297.54,297.54,Low tissue specificity,Cell type enhanced,188,CDH1(0.999)|CREBBP(0.999)|CSNK1A1(0.999)|EP300(0.999)|GSK3B(0.999)
CTSB,cathepsin B,ENSG00000164733,1508,P07858,CellAge|SenMayo,2,TRUE,Ctsb,78.7611,TRUE,Thyroid,1137.27,1137.27,Tissue enhanced,Cell type enhanced,13,CTSD(0.977)|BCL2(0.947)|BCL2L1(0.938)|APP(0.902)|MMP9(0.897)
CTSD,cathepsin D,ENSG00000117984,1509,P07339,CellAge,1,TRUE,Ctsd,80.5825,TRUE,Adrenal_Gland,1571.01,1571.01,Low tissue specificity,Cell type enhanced,13,CTSB(0.977)|BCL2(0.949)|BCL2L1(0.934)|AGT(0.909)|GRN(0.866)
CUL4B,cullin 4B,ENSG00000158290,8450,Q13620,CellAge,1,TRUE,Cul4b,97.4302,TRUE,Cells_Cultured_fibroblasts,95.89,95.89,Low tissue specificity,Cell type enhanced,11,DDB1(0.999)|DTL(0.999)|RBX1(0.999)|DDB2(0.998)|ERCC8(0.984)
CUX1,cut like homeobox 1,ENSG00000257923,1523,P39880,CellAge,1,TRUE,Cux1,88.0399,TRUE,Uterus,47.88,47.88,Low tissue specificity,Cell type enhanced,7,EWSR1(0.834)|CCNA1(0.825)|BCL11B(0.821)|SOX2(0.804)|CCNA2(0.77)
CXCL1,C-X-C motif chemokine ligand 1,ENSG00000163739,2919,P09341,CellAge|SenMayo,2,FALSE,,,FALSE,Spleen,213.56,213.56,Tissue enhanced,Cell type enhanced,45,CXCR2(0.999)|CXCL2(0.996)|CXCL3(0.996)|ACKR1(0.993)|CXCL10(0.992)
CXCL10,C-X-C motif chemokine ligand 10,ENSG00000169245,3627,P02778,SenMayo,1,TRUE,Cxcl10,68.3673,FALSE,Lung,11.93,11.93,Tissue enhanced,Cell type enhanced,52,CCL13(0.999)|CCL5(0.999)|CCL8(0.999)|CXCL12(0.999)|CCL26(0.998)
CXCL12,C-X-C motif chemokine ligand 12,ENSG00000107562,6387,P48061,SenMayo,1,TRUE,Cxcl12,93.2584,TRUE,Cervix_Ectocervix,170.59,170.59,Low tissue specificity,Cell type enhanced,56,CCL20(0.999)|CCL5(0.999)|CXCL10(0.999)|CXCL2(0.999)|CCL13(0.998)
CXCL16,C-X-C motif chemokine ligand 16,ENSG00000161921,58191,Q9H2A7,SenMayo,1,TRUE,Cxcl16,44.8819,FALSE,Testis,194.26,194.26,Low tissue specificity,Cell type enriched,15,CXCR2(0.921)|CXCL1(0.907)|CXCL10(0.902)|CCL5(0.898)|CCL20(0.849)
CXCL2,C-X-C motif chemokine ligand 2,ENSG00000081041,2920,P19875,SenMayo,1,FALSE,,,FALSE,Liver,256.13,256.13,Tissue enriched,Cell type enhanced,34,CCL5(0.999)|CXCL12(0.999)|CXCR2(0.999)|CCL8(0.998)|CXCL1(0.996)
CXCL3,C-X-C motif chemokine ligand 3,ENSG00000163734,2921,P19876,SenMayo,1,TRUE,Cxcl2,59.8131,FALSE,Lung,19.09,19.09,Tissue enhanced,Cell type enhanced,22,CXCR2(0.999)|CXCL1(0.996)|CXCL2(0.995)|CXCL10(0.971)|CCL20(0.951)
CXCL8,C-X-C motif chemokine ligand 8,ENSG00000169429,3576,P10145,Reactome|SenMayo,2,FALSE,,,FALSE,Lung,52.52,52.52,Tissue enriched,Cell type enhanced,91,ACKR1(0.999)|CCL2(0.999)|CXCR2(0.999)|CCL8(0.998)|RELA(0.995)
CXCR2,C-X-C motif chemokine receptor 2,ENSG00000180871,3579,P25025,CellAge|SenMayo,2,TRUE,Cxcr2,70.8333,TRUE,Whole_Blood,312.75,312.75,Tissue enhanced,Cell type enriched,34,CXCL1(0.999)|CXCL2(0.999)|CXCL3(0.999)|CXCL8(0.999)|CXCL12(0.998)
CYB5R3,cytochrome b5 reductase 3,ENSG00000100243,1727,P00387,CellAge,1,TRUE,Cyb5r3,87.3754,TRUE,Artery_Aorta,741.66,741.66,Low tissue specificity,Cell type enhanced,0,
CYBB,cytochrome b-245 beta chain,ENSG00000165168,1536,P04839,CellAge,1,TRUE,Cybb,92.807,TRUE,Whole_Blood,93.49,93.49,Tissue enhanced,Cell type enhanced,23,NOX1(0.998)|NOX4(0.998)|AKT1(0.994)|MMP9(0.963)|MMP2(0.957)
CYP26A1,cytochrome P450 family 26 subfamily A member 1,ENSG00000095596,1592,O43174,CellAge,1,TRUE,Cyp26a1,93.9638,TRUE,Liver,4.5,4.5,Tissue enriched,Cell type enhanced,4,DGAT1(0.927)|RBP2(0.813)|RARB(0.739)|RBP1(0.719)
DAO,D-amino acid oxidase,ENSG00000110887,1610,P14920,CellAge,1,TRUE,Dao,80.4035,TRUE,Brain_Cerebellum,40.12,40.12,Group enriched,Group enriched,2,GNMT(0.91)|CTH(0.75)
DBN1,drebrin 1,ENSG00000113758,1627,Q16643,GenAge,1,TRUE,Dbn1,80.5755,TRUE,Cells_Cultured_fibroblasts,138.43,138.43,Low tissue specificity,Cell type enhanced,1,GJA1(0.906)
DDAH2,"DDAH family member 2, ADMA-independent",ENSG00000226634,23564,O95865,CellAge,1,FALSE,,,FALSE,,,,,,1,PRMT1(0.759)
DDB1,damage specific DNA binding protein 1,ENSG00000167986,1642,Q16531,CellAge,1,TRUE,Ddb1,99.6491,TRUE,Adrenal_Gland,234.56,234.56,Low tissue specificity,Cell type enhanced,44,CUL4B(0.999)|DDB2(0.999)|DTL(0.999)|ERCC8(0.999)|RBX1(0.999)
DDB2,damage specific DNA binding protein 2,ENSG00000134574,1643,Q92466,CellAge,1,TRUE,Ddb2,78.4543,TRUE,Cells_EBV-transformed_lymphocytes,99.38,99.38,Low tissue specificity,Cell type enhanced,30,DDB1(0.999)|RBX1(0.999)|CUL4B(0.998)|XPA(0.989)|XPC(0.982)
DDIT3,DNA damage inducible transcript 3,ENSG00000175197,1649,P35638,GenAge,1,TRUE,Ddit3,88.1657,TRUE,Thyroid,128.36,128.36,Low tissue specificity,Cell type enriched,18,CEBPB(0.994)|ATF6(0.989)|ATF3(0.988)|BCL2(0.972)|NFE2L2(0.968)
DDIT4,DNA damage inducible transcript 4,ENSG00000168209,54541,Q9NX09,CellAge,1,TRUE,Ddit4,90.5172,TRUE,Ovary,877.64,877.64,Low tissue specificity,Cell type enhanced,8,TXNIP(0.991)|TP53(0.911)|TP63(0.842)|RPTOR(0.84)|MTOR(0.8)
DEK,DEK proto-oncogene,ENSG00000124795,7913,P35659,CellAge,1,TRUE,Dek,90.6667,TRUE,Cells_EBV-transformed_lymphocytes,163.24,163.24,Low tissue specificity,Cell type enhanced,11,MYBBP1A(0.932)|H2AC20(0.888)|SPOP(0.888)|H2BC21(0.878)|ERCC6(0.852)
DEPTOR,DEP domain containing MTOR interacting protein,ENSG00000155792,64798,Q8TB45,CellAge,1,TRUE,Deptor,51.5892,TRUE,Muscle_Skeletal,101.88,101.88,Tissue enhanced,Cell type enhanced,6,AKT1S1(0.999)|MTOR(0.999)|RICTOR(0.999)|RPTOR(0.999)|RPS6KB1(0.991)
DGAT1,diacylglycerol O-acyltransferase 1,ENSG00000185000,8694,O75907,GenAge,1,TRUE,Dgat1,86.2705,TRUE,Small_Intestine_Terminal_Ileum,136.63,136.63,Tissue enhanced,Cell type enhanced,4,CYP26A1(0.927)|SREBF1(0.779)|FASN(0.768)|PPARA(0.721)
DGCR8,DGCR8 microprocessor complex subunit,ENSG00000128191,54487,Q8WYQ5,CellAge,1,TRUE,Dgcr8,95.3428,TRUE,Brain_Cerebellum,80,80,Low tissue specificity,Cell type enhanced,13,DICER1(0.993)|METTL14(0.989)|AGO2(0.984)|MECP2(0.974)|AGO1(0.952)
DHCR24,24-dehydrocholesterol reductase,ENSG00000116133,1718,Q15392,CellAge,1,TRUE,Dhcr24,96.8992,TRUE,Adrenal_Gland,1544.19,1544.19,Tissue enhanced,Cell type enhanced,5,LBR(0.95)|HMGCR(0.829)|FDPS(0.795)|MVK(0.741)|TP53(0.706)
DHRS2,dehydrogenase/reductase 2,ENSG00000100867,10202,Q13268,CellAge,1,TRUE,Dhrs2,64.2857,TRUE,Bladder,115.16,115.16,Tissue enhanced,Cell type enriched,0,
DHX9,DExH-box helicase 9,ENSG00000135829,1660,Q08211,CellAge,1,TRUE,Dhx9,91.5748,TRUE,Cells_EBV-transformed_lymphocytes,106.58,106.58,Low tissue specificity,Low cell type specificity,38,AGO2(0.999)|EWSR1(0.997)|YBX1(0.994)|HNRNPC(0.992)|DICER1(0.987)
DICER1,"dicer 1, ribonuclease III",ENSG00000100697,23405,Q9UPY3,CellAge,1,TRUE,Dicer1,92.4037,TRUE,Nerve_Tibial,46.07,46.07,Low tissue specificity,Cell type enhanced,20,AGO1(0.999)|AGO2(0.999)|TNRC6A(0.998)|DGCR8(0.993)|AGO3(0.991)
DIDO1,death inducer-obliterator 1,ENSG00000101191,11083,Q9BTC0,CellAge,1,TRUE,Dido1,74.7321,TRUE,Uterus,34.34,34.34,Low tissue specificity,Low cell type specificity,7,H3-4(0.98)|H3C1(0.945)|H3-3A(0.932)|H3C15(0.932)|DPY30(0.867)
DIRAS3,DIRAS family GTPase 3,ENSG00000162595,9077,O95661,CellAge,1,FALSE,,,FALSE,Brain_Hypothalamus,139.47,139.47,Group enriched,Cell type enhanced,1,PIK3CB(0.917)
DKC1,dyskerin pseudouridine synthase 1,ENSG00000130826,1736,O60832,CellAge,1,TRUE,Dkc1,91.0506,TRUE,Cells_EBV-transformed_lymphocytes,106.01,106.01,Low tissue specificity,Cell type enhanced,18,GAR1(0.999)|TERT(0.999)|NOLC1(0.997)|RUVBL2(0.995)|TINF2(0.97)
DKK1,dickkopf Wnt signaling pathway inhibitor 1,ENSG00000107984,22943,O94907,SenMayo,1,TRUE,Dkk1,82.7068,FALSE,Cells_Cultured_fibroblasts,852.85,852.85,Tissue enhanced,Cell type enriched,10,CTNNB1(0.963)|WNT5A(0.942)|WNT2(0.909)|SFRP1(0.883)|WIF1(0.882)
DLC1,DLC1 Rho GTPase activating protein,ENSG00000164741,10395,Q96QB1,CellAge,1,TRUE,Dlc1,84.6204,TRUE,Lung,46.9,46.9,Low tissue specificity,Cell type enhanced,3,RHOA(0.903)|CAV1(0.785)|CDC42(0.754)
DLL3,delta like canonical Notch ligand 3,ENSG00000090932,10683,Q9NYJ7,GenAge,1,TRUE,Dll3,83.4753,FALSE,Brain_Nucleus_accumbens_basal_ganglia,11.43,11.43,Tissue enriched,Cell type enhanced,4,NOTCH1(0.998)|NOTCH3(0.998)|EGF(0.756)|RBPJ(0.753)
DMTF1,cyclin D binding myb like transcription factor 1,ENSG00000135164,9988,Q9Y222,CellAge,1,TRUE,Dmtf1,95.1316,TRUE,Ovary,84.03,84.03,Low tissue specificity,Low cell type specificity,1,TP53(0.768)
DNMT1,DNA methyltransferase 1,ENSG00000130816,1786,P26358,CellAge,1,TRUE,Dnmt1,77.451,TRUE,Cells_EBV-transformed_lymphocytes,83.96,83.96,Low tissue specificity,Cell type enhanced,63,DNMT3A(0.999)|DNMT3B(0.999)|EZH2(0.999)|HDAC1(0.999)|HDAC2(0.999)
DNMT3A,DNA methyltransferase 3 alpha,ENSG00000119772,1788,Q9Y6K1,CellAge,1,TRUE,Dnmt3a,95.943,TRUE,Brain_Cerebellum,20.9,20.9,Low tissue specificity,Cell type enhanced,42,DNMT1(0.999)|EZH2(0.999)|DNMT3B(0.998)|H3-4(0.998)|HDAC1(0.997)
DNMT3B,DNA methyltransferase 3 beta,ENSG00000088305,1789,Q9UBC3,CellAge,1,TRUE,Dnmt3b,83.4701,TRUE,Testis,12.84,12.84,Tissue enhanced,Cell type enhanced,42,DNMT1(0.999)|EZH2(0.999)|HDAC1(0.999)|DNMT3A(0.998)|H3-4(0.994)
DOT1L,DOT1 like histone lysine methyltransferase,ENSG00000104885,84444,Q8TEK3,CellAge,1,TRUE,Dot1l,84.4502,TRUE,Testis,111.67,111.67,Tissue enhanced,Cell type enhanced,25,H2BC11(0.964)|H2BC12(0.964)|RPS27A(0.96)|UBC(0.955)|UBB(0.949)
DPP4,dipeptidyl peptidase 4,ENSG00000197635,1803,P27487,CellAge,1,TRUE,Dpp4,84.4648,TRUE,Cells_Cultured_fibroblasts,48.83,48.83,Tissue enhanced,Cell type enhanced,11,CAV1(0.991)|MME(0.962)|SLC5A2(0.909)|INS(0.906)|CD9(0.882)
DPY30,dpy-30 histone methyltransferase complex regulatory subunit,ENSG00000162961,84661,Q9C005,CellAge,1,TRUE,Dpy30,97.9798,TRUE,Thyroid,56.32,56.32,Low tissue specificity,Cell type enhanced,16,SETD1A(0.999)|RPS27A(0.964)|UBA52(0.962)|MEN1(0.925)|UBC(0.87)
DTL,denticleless E3 ubiquitin protein ligase adapter,ENSG00000143476,51514,Q9NZJ0,CellAge,1,TRUE,Dtl,89.4521,TRUE,Cells_EBV-transformed_lymphocytes,38.2,38.2,Group enriched,Cell type enhanced,27,CUL4B(0.999)|DDB1(0.999)|PCNA(0.995)|RBX1(0.995)|DDB2(0.98)
DUSP1,dual specificity phosphatase 1,ENSG00000120129,1843,P28562,CellAge,1,TRUE,Dusp1,96.4578,TRUE,Artery_Aorta,1984.27,1984.27,Low tissue specificity,Cell type enhanced,17,MAPK14(0.998)|MAPK1(0.996)|MAPK3(0.996)|MAPK8(0.992)|MAPK11(0.973)
DUSP16,dual specificity phosphatase 16,ENSG00000280962,80824,Q9BY84,CellAge,1,FALSE,,,FALSE,,,,,,7,MAPK8(0.998)|MAPK9(0.985)|MAPK14(0.95)|MAPK12(0.887)|MAPK11(0.882)
DUSP21,dual specificity phosphatase 21,ENSG00000189037,63904,Q9H596,CellAge,1,TRUE,Dusp21,69.4737,FALSE,Testis,20.41,20.41,Tissue enriched,Cell type enriched,0,
DUSP3,dual specificity phosphatase 3,ENSG00000108861,1845,P51452,CellAge,1,FALSE,,,FALSE,Muscle_Skeletal,120.39,120.39,Tissue enhanced,Cell type enhanced,7,MAPK1(0.979)|MAPK3(0.973)|MAPK14(0.936)|MAPK8(0.935)|MAPK12(0.93)
DUSP6,dual specificity phosphatase 6,ENSG00000139318,1848,Q16828,CellAge,1,TRUE,Dusp6,98.1627,TRUE,Adipose_Visceral_Omentum,91.55,91.55,Tissue enhanced,Cell type enhanced,5,MAPK1(0.996)|MAPK3(0.985)|FOS(0.743)|EGR1(0.729)|MAPK7(0.709)
DYRK1A,dual specificity tyrosine phosphorylation regulated kinase 1A,ENSG00000157540,1859,Q13627,CellAge,1,TRUE,Dyrk1a,99.2042,TRUE,Uterus,35.25,35.25,Low tissue specificity,Cell type enhanced,6,LIN52(0.903)|GSK3B(0.808)|YWHAB(0.754)|MAPT(0.748)|FNTB(0.742)
E2F1,E2F transcription factor 1,ENSG00000101412,1869,Q01094,CellAge|GenAge|Reactome,3,TRUE,E2f1,84.4394,TRUE,Cells_EBV-transformed_lymphocytes,45.55,45.55,Tissue enhanced,Cell type enhanced,90,CCNA1(0.999)|CCNA2(0.999)|HDAC1(0.999)|RB1(0.999)|TFDP1(0.999)
E2F2,E2F transcription factor 2,ENSG00000007968,1870,Q14209,Reactome,1,TRUE,E2f2,83.2952,FALSE,Esophagus_Mucosa,12.83,12.83,Group enriched,Cell type enriched,25,RB1(0.999)|E2F1(0.993)|TFDP1(0.989)|RBL2(0.987)|RBL1(0.983)
E2F3,E2F transcription factor 3,ENSG00000112242,1871,O00716,CellAge|Reactome,2,TRUE,E2f3,94.1936,TRUE,Cells_EBV-transformed_lymphocytes,16.65,16.65,Low tissue specificity,Cell type enhanced,26,RB1(0.998)|TFDP1(0.996)|RBL1(0.985)|RBL2(0.984)|E2F1(0.979)
E2F7,E2F transcription factor 7,ENSG00000165891,144455,Q96AV8,CellAge,1,TRUE,E2f7,79.1438,TRUE,Cells_EBV-transformed_lymphocytes,20.11,20.11,Tissue enhanced,Cell type enhanced,4,E2F1(0.939)|CDC6(0.916)|TP53(0.895)|HIF1A(0.806)
ECT2,epithelial cell transforming 2,ENSG00000114346,1894,Q9H8V3,CellAge,1,TRUE,Ect2,88.0744,TRUE,Cells_EBV-transformed_lymphocytes,23.49,23.49,Low tissue specificity,Cell type enhanced,26,RACGAP1(0.999)|ANLN(0.994)|RHOA(0.966)|CDK1(0.963)|BUB1(0.947)
EDN1,endothelin 1,ENSG00000078401,1906,P05305,SenMayo,1,TRUE,Edn1,69.3396,FALSE,Adipose_Subcutaneous,64.46,64.46,Tissue enhanced,Cell type enhanced,19,MMP9(0.963)|MMP2(0.958)|AGT(0.953)|AGTR1(0.898)|CXCL8(0.803)
EED,embryonic ectoderm development,ENSG00000074266,8726,O75530,Reactome,1,TRUE,Eed,100,TRUE,Cells_EBV-transformed_lymphocytes,56.07,56.07,Low tissue specificity,Low cell type specificity,32,EZH2(0.999)|RBBP4(0.999)|RBBP7(0.999)|SUZ12(0.999)|RNF2(0.997)
EEF1A1,eukaryotic translation elongation factor 1 alpha 1,ENSG00000156508,1915,P68104,GenAge,1,TRUE,Eef1a1,99.7835,TRUE,Cells_Cultured_fibroblasts,5147.17,5147.17,Low tissue specificity,Cell type enhanced,24,RACK1(0.993)|RPS9(0.989)|RPL11(0.987)|RPS27A(0.984)|EEF2(0.982)
EEF1E1,eukaryotic translation elongation factor 1 epsilon 1,ENSG00000124802,9521,O43324,CellAge|GenAge,2,TRUE,Eef1e1,87.931,TRUE,Testis,34.29,34.29,Low tissue specificity,Group enriched,1,ATM(0.838)
EEF2,eukaryotic translation elongation factor 2,ENSG00000167658,1938,P13639,GenAge,1,TRUE,Eef2,99.0676,TRUE,Ovary,2998.09,2998.09,Low tissue specificity,Cell type enhanced,21,RACK1(0.999)|RPL11(0.999)|RPS9(0.999)|UBA52(0.998)|RPS27A(0.997)
EFEMP1,EGF-like fibulin extracellular matrix protein 1,ENSG00000115380,2202,Q12805,GenAge,1,TRUE,Efemp1,94.5233,TRUE,Artery_Aorta,1495.93,1495.93,Tissue enhanced,Cell type enhanced,1,EGFR(0.877)
EGF,epidermal growth factor,ENSG00000138798,1950,P01133,GenAge|SenMayo,2,TRUE,Egf,66.4457,TRUE,Kidney_Medulla,43.56,43.56,Group enriched,Cell type enriched,98,EGFR(0.999)|ERBB2(0.999)|AREG(0.998)|IGF1R(0.997)|GRB2(0.995)
EGFR,epidermal growth factor receptor,ENSG00000146648,1956,P00533,CellAge|GenAge|SenMayo,3,TRUE,Egfr,90.4959,TRUE,Skin_Sun_Exposed_Lower_leg,78.34,78.34,Tissue enhanced,Cell type enhanced,184,AREG(0.999)|CAV1(0.999)|CDH1(0.999)|EGF(0.999)|ERBB2(0.999)
EGLN1,egl-9 family hypoxia inducible factor 1,ENSG00000135766,54583,Q9GZT9,CellAge,1,TRUE,Egln1,74.1784,TRUE,Muscle_Skeletal,155.85,155.85,Group enriched,Cell type enhanced,7,EPAS1(0.999)|HIF1A(0.999)|PRKCA(0.911)|HSP90AB1(0.833)|HSP90AA1(0.782)
EGR1,early growth response 1,ENSG00000120738,1958,P18146,GenAge,1,TRUE,Egr1,91.5285,FALSE,Fallopian_Tube,1108.48,1108.48,Low tissue specificity,Cell type enhanced,41,FOS(0.995)|JUN(0.99)|EGR2(0.98)|JUNB(0.97)|TP53(0.969)
EGR2,early growth response 2,ENSG00000122877,1959,P11161,CellAge,1,TRUE,Egr2,89.4958,TRUE,Nerve_Tibial,62.63,62.63,Tissue enhanced,Cell type enhanced,20,EGR1(0.98)|FOS(0.963)|EP300(0.923)|CREBBP(0.92)|JUN(0.888)
EHF,ETS homologous factor,ENSG00000135373,26298,Q9NZC4,CellAge,1,TRUE,Ehf,93.6667,TRUE,Minor_Salivary_Gland,167.42,167.42,Tissue enhanced,Cell type enhanced,0,
EHMT1,euchromatic histone lysine methyltransferase 1,ENSG00000181090,79813,Q9H9B1,Reactome,1,TRUE,Ehmt1,88.2126,TRUE,Cells_EBV-transformed_lymphocytes,21.64,21.64,Low tissue specificity,Cell type enhanced,17,EHMT2(0.999)|H3C1(0.979)|H3-4(0.972)|HDAC1(0.942)|H3-3A(0.923)
EHMT2,euchromatic histone lysine methyltransferase 2,ENSG00000232045,10919,Q96KQ7,CellAge|Reactome,2,FALSE,,,FALSE,,,,,,47,EHMT1(0.999)|HDAC1(0.999)|DNMT1(0.998)|UHRF1(0.997)|H3-4(0.996)
EID3,EP300 interacting inhibitor of differentiation 3,ENSG00000255150,493861,Q8N140,CellAge,1,TRUE,Eid3,69.6697,TRUE,Testis,132.68,132.68,Tissue enriched,Not detected,2,CREBBP(0.714)|SMC1A(0.7)
EIF2AK2,eukaryotic translation initiation factor 2 alpha kinase 2,ENSG00000055332,5610,P19525,CellAge,1,TRUE,Eif2ak2,56.8058,FALSE,Cells_EBV-transformed_lymphocytes,61.97,61.97,Low tissue specificity,Low cell type specificity,26,STAT1(0.98)|CHUK(0.977)|ILF3(0.977)|IKBKB(0.966)|IRS1(0.966)
EIF2AK3,eukaryotic translation initiation factor 2 alpha kinase 3,ENSG00000172071,9451,Q9NZJ5,CellAge,1,TRUE,Eif2ak3,87.3656,TRUE,Cells_EBV-transformed_lymphocytes,45.25,45.25,Tissue enhanced,Cell type enhanced,17,HSPA5(0.999)|ATF6(0.978)|NFE2L2(0.977)|PSEN1(0.942)|IKBKG(0.923)
EIF4E,eukaryotic translation initiation factor 4E,ENSG00000151247,1977,P06730,CellAge,1,TRUE,Eif4e,98.1567,TRUE,Brain_Cerebellar_Hemisphere,14.93,14.93,Low tissue specificity,Cell type enhanced,31,EIF4EBP1(0.999)|EIF4G2(0.999)|AGO2(0.991)|RPS6KB1(0.985)|AGO1(0.983)
EIF4EBP1,eukaryotic translation initiation factor 4E binding protein 1,ENSG00000187840,1978,Q13541,CellAge,1,TRUE,Eif4ebp1,90.678,TRUE,Cells_Cultured_fibroblasts,188.04,188.04,Tissue enhanced,Cell type enhanced,13,EIF4E(0.999)|MTOR(0.999)|RPTOR(0.999)|MAPK1(0.978)|AKT1S1(0.977)
EIF4G2,eukaryotic translation initiation factor 4 gamma 2,ENSG00000110321,1982,P78344,CellAge,1,TRUE,Eif4g2,98.8975,TRUE,Cells_Cultured_fibroblasts,507.48,507.48,Low tissue specificity,Cell type enhanced,1,EIF4E(0.999)
EIF5A2,eukaryotic translation initiation factor 5A2,ENSG00000163577,56648,Q9GZV4,GenAge,1,TRUE,Eif5a2,100,TRUE,Testis,11.48,11.48,Tissue enhanced,Cell type enhanced,8,RPL11(0.949)|UBA52(0.937)|RACK1(0.935)|RPS9(0.886)|EEF2(0.875)
ELAVL1,ELAV like RNA binding protein 1,ENSG00000066044,1994,Q15717,CellAge,1,TRUE,Elavl1,98.4663,TRUE,Cells_EBV-transformed_lymphocytes,55.47,55.47,Low tissue specificity,Cell type enhanced,37,AGO2(0.997)|HNRNPC(0.976)|PTBP1(0.974)|HNRNPD(0.97)|HNRNPA1(0.965)
ELN,elastin,ENSG00000049540,2006,P15502,GenAge,1,TRUE,Eln,76.5193,FALSE,Artery_Aorta,1681.2,1681.2,Tissue enriched,Cell type enhanced,18,LOX(0.992)|LGALS3(0.984)|MMP9(0.979)|MMP12(0.958)|LOXL2(0.934)
ELOA,elongin A,ENSG00000011007,6924,Q14241,CellAge,1,TRUE,Eloa,82.6425,TRUE,Cells_Cultured_fibroblasts,42.14,42.14,Low tissue specificity,Low cell type specificity,4,LEO1(0.984)|ERCC6(0.953)|SUPT5H(0.943)|RPL11(0.924)
EMD,emerin,ENSG00000102119,2010,P50402,GenAge,1,TRUE,Emd,75.9843,FALSE,Ovary,236.64,236.64,Low tissue specificity,Cell type enhanced,9,LMNA(0.999)|SUN1(0.998)|LMNB1(0.994)|CTNNB1(0.973)|BCLAF1(0.971)
ENDOG,endonuclease G,ENSG00000167136,2021,Q14249,CellAge,1,TRUE,Endog,89.5623,TRUE,Muscle_Skeletal,50.04,50.04,Tissue enhanced,Cell type enhanced,4,AIFM1(0.946)|HTRA2(0.816)|FEN1(0.791)|BCL2(0.707)
ENG,endoglin,ENSG00000106991,2022,P17813,CellAge,1,TRUE,Eng,71.5805,TRUE,Artery_Aorta,476.7,476.7,Tissue enhanced,Cell type enhanced,20,TGFB1(0.998)|TGFBR2(0.997)|BMPR2(0.979)|TGFBR1(0.969)|PECAM1(0.923)
ENO1,enolase 1,ENSG00000074800,2023,P06733,CellAge,1,TRUE,Eno1,94.7005,TRUE,Cells_EBV-transformed_lymphocytes,3707.37,3707.37,Low tissue specificity,Cell type enhanced,22,GAPDH(0.998)|ALDOA(0.988)|PCK1(0.962)|EGFR(0.928)|G6PD(0.903)
ENTPD7,ectonucleoside triphosphate diphosphohydrolase 7,ENSG00000198018,57089,Q9NQZ7,CellAge,1,TRUE,Entpd7,92.3841,FALSE,Cells_Cultured_fibroblasts,12.7,12.7,Tissue enhanced,Cell type enhanced,0,
EP300,EP300 lysine acetyltransferase,ENSG00000100393,2033,Q09472,CellAge|GenAge,2,TRUE,Ep300,93.9105,TRUE,Testis,49.45,49.45,Low tissue specificity,Cell type enhanced,174,CARM1(0.999)|CREB1(0.999)|CREBBP(0.999)|CTNNB1(0.999)|HDAC1(0.999)
EP400,E1A binding protein p400,ENSG00000183495,57634,Q96L91,Reactome,1,TRUE,Ep400,84.1499,TRUE,Ovary,29.03,29.03,Low tissue specificity,Low cell type specificity,20,KAT5(0.999)|RUVBL2(0.999)|TRRAP(0.999)|YEATS4(0.999)|MORF4L1(0.997)
EPAS1,endothelial PAS domain protein 1,ENSG00000116016,2034,Q99814,CellAge,1,TRUE,Epas1,88.2759,TRUE,Lung,1031.42,1031.42,Tissue enhanced,Cell type enhanced,28,EGLN1(0.999)|EP300(0.998)|HIF1A(0.998)|CREBBP(0.986)|POU5F1(0.955)
EPHA3,EPH receptor A3,ENSG00000044524,2042,P29320,CellAge,1,TRUE,Epha3,96.5412,TRUE,Prostate,18.85,18.85,Tissue enhanced,Cell type enhanced,2,ABL1(0.958)|EPHA5(0.884)
EPHA5,EPH receptor A5,ENSG00000145242,2044,P54756,CellAge,1,TRUE,Epha5,81.0039,FALSE,Brain_Frontal_Cortex_BA9,5.08,5.08,Tissue enriched,Cell type enhanced,2,ABL1(0.963)|EPHA3(0.884)
EPOR,erythropoietin receptor,ENSG00000187266,2057,P19235,CellAge|GenAge,2,TRUE,Epor,81.6929,TRUE,Thyroid,191.85,191.85,Low tissue specificity,Cell type enhanced,23,JAK2(0.999)|STAT5A(0.989)|CSF2RB(0.985)|GRB2(0.978)|STAT5B(0.972)
EPS8,"EGFR pathway substrate 8, signaling adaptor",ENSG00000151491,2059,Q12929,GenAge,1,TRUE,Eps8,88.8078,TRUE,Artery_Tibial,170.12,170.12,Low tissue specificity,Cell type enhanced,3,EGFR(0.952)|CDC42(0.751)|SRC(0.715)
ERBB2,erb-b2 receptor tyrosine kinase 2,ENSG00000141736,2064,P04626,CellAge|GenAge,2,TRUE,Erbb2,87.6494,TRUE,Nerve_Tibial,130.13,130.13,Low tissue specificity,Cell type enhanced,92,EGF(0.999)|EGFR(0.999)|GRB2(0.999)|HSP90AA1(0.999)|NRG1(0.999)
ERCC1,"ERCC excision repair 1, endonuclease non-catalytic subunit",ENSG00000012061,2067,P07992,CellAge|GenAge,2,TRUE,Ercc1,85.8586,TRUE,Cells_Cultured_fibroblasts,56.96,56.96,Low tissue specificity,Cell type enriched,44,ERCC4(0.999)|XPA(0.999)|MUS81(0.998)|RAD23B(0.998)|ERCC5(0.997)
ERCC2,"ERCC excision repair 2, TFIIH core complex helicase subunit",ENSG00000104884,2068,P18074,GenAge,1,TRUE,Ercc2,97.5,TRUE,Cells_Cultured_fibroblasts,40.38,40.38,Low tissue specificity,Cell type enhanced,35,CDK7(0.999)|ERCC3(0.999)|ERCC5(0.999)|GTF2H2(0.999)|XPA(0.999)
ERCC3,"ERCC excision repair 3, TFIIH core complex helicase subunit",ENSG00000163161,2071,P19447,GenAge,1,TRUE,Ercc3,95.9079,TRUE,Brain_Cerebellar_Hemisphere,90.06,90.06,Low tissue specificity,Low cell type specificity,37,CDK7(0.999)|ERCC2(0.999)|ERCC5(0.999)|GTF2H2(0.999)|XPA(0.999)
ERCC4,"ERCC excision repair 4, endonuclease catalytic subunit",ENSG00000175595,2072,Q92889,GenAge,1,TRUE,Ercc4,86.0262,TRUE,Testis,13.77,13.77,Tissue enhanced,Cell type enhanced,41,ERCC1(0.999)|XPA(0.999)|ERCC5(0.998)|MUS81(0.994)|RAD23B(0.99)
ERCC5,"ERCC excision repair 5, endonuclease",ENSG00000134899,2073,P28715,GenAge,1,TRUE,Ercc5,65.5143,TRUE,Cells_EBV-transformed_lymphocytes,4.66,4.66,Low tissue specificity,Group enriched,33,ERCC2(0.999)|ERCC3(0.999)|ERCC6(0.999)|ERCC4(0.998)|GTF2H2(0.998)
ERCC6,"ERCC excision repair 6, chromatin remodeling factor",ENSG00000225830,2074,P0DP91,GenAge,1,TRUE,Ercc6,78.5666,TRUE,Artery_Aorta,9.31,9.31,Low tissue specificity,Cell type enhanced,29,ERCC5(0.999)|ERCC8(0.999)|XPA(0.99)|DDB1(0.988)|LEO1(0.985)
ERCC8,"ERCC excision repair 8, CSA ubiquitin ligase complex subunit",ENSG00000049167,1161,Q13216,GenAge,1,TRUE,Ercc8,89.3939,TRUE,Cells_Cultured_fibroblasts,10.04,10.04,Low tissue specificity,Cell type enhanced,24,DDB1(0.999)|ERCC6(0.999)|RBX1(0.994)|ERCC5(0.99)|CUL4B(0.984)
EREG,epiregulin,ENSG00000124882,2069,O14944,SenMayo,1,TRUE,Ereg,78.1065,FALSE,Skin_Sun_Exposed_Lower_leg,14.16,14.16,Tissue enriched,Cell type enhanced,15,EGFR(0.999)|AREG(0.998)|EGF(0.958)|ERBB2(0.86)|NRG1(0.845)
ERF,ETS2 repressor factor,ENSG00000105722,2077,P50548,Reactome,1,TRUE,Erf,96.8978,TRUE,Fallopian_Tube,95.02,95.02,Low tissue specificity,Cell type enhanced,3,MAPK3(0.876)|MAPK1(0.858)|ETS2(0.807)
ERRFI1,ERBB receptor feedback inhibitor 1,ENSG00000116285,54206,Q9UJM3,CellAge,1,TRUE,Errfi1,82.0346,TRUE,Artery_Tibial,291.48,291.48,Tissue enhanced,Cell type enhanced,3,EGFR(0.996)|GRB2(0.84)|ERBB2(0.812)
ERVW-1,"endogenous retrovirus group W member 1, envelope",ENSG00000242950,30816,Q9UQF0,CellAge,1,TRUE,BC035947,15.0558,FALSE,Testis,20.01,20.01,Tissue enriched,Group enriched,7,TLR4(0.982)|CDH1(0.932)|ICAM3(0.756)|C3(0.743)|EGF(0.739)
ESM1,endothelial cell specific molecule 1,ENSG00000164283,11082,Q9NQ30,SenMayo,1,TRUE,Esm1,75,TRUE,Kidney_Cortex,11.6,11.6,Tissue enhanced,Cell type enhanced,0,
ESPL1,"extra spindle pole bodies like 1, separase",ENSG00000135476,9700,Q14674,CellAge,1,TRUE,Espl1,77.2642,TRUE,Esophagus_Mucosa,33.49,33.49,Tissue enhanced,Cell type enriched,43,CCNB1(0.999)|PTTG1(0.999)|RAD21(0.997)|CDK1(0.995)|PLK1(0.994)
ESR1,estrogen receptor 1,ENSG00000091831,2099,P03372,CellAge|GenAge,2,TRUE,Esr1,89.5798,TRUE,Cervix_Endocervix,88.87,88.87,Tissue enhanced,Cell type enhanced,126,BRCA1(0.999)|FOS(0.999)|HSP90AA1(0.999)|IGF1R(0.999)|JUN(0.999)
ESRRB,estrogen related receptor beta,ENSG00000119715,2103,O95718,CellAge,1,TRUE,Esrrb,93.3921,TRUE,Kidney_Medulla,11.83,11.83,Group enriched,Group enriched,8,NANOG(0.932)|POU5F1(0.905)|SOX2(0.86)|EGFR(0.848)|TBX3(0.827)
ETS1,"ETS proto-oncogene 1, transcription factor",ENSG00000134954,2113,P14921,CellAge|Reactome,2,TRUE,Ets1,62.0619,TRUE,Cells_EBV-transformed_lymphocytes,124.44,124.44,Tissue enhanced,Cell type enhanced,21,RUNX1(0.999)|MAPK1(0.992)|FOXO1(0.978)|TP53(0.972)|ETS2(0.958)
ETS2,"ETS proto-oncogene 2, transcription factor",ENSG00000157557,2114,P15036,CellAge|Reactome|SenMayo,3,TRUE,Ets2,91.258,FALSE,Skin_Not_Sun_Exposed_Suprapubic,289.19,289.19,Low tissue specificity,Cell type enhanced,12,TP53(0.97)|ETS1(0.958)|ID1(0.958)|MAPK1(0.945)|MAPK3(0.929)
ETV6,ETS variant transcription factor 6,ENSG00000139083,2120,P41212,CellAge,1,TRUE,Etv6,89.3805,FALSE,Artery_Tibial,45.05,45.05,Low tissue specificity,Cell type enhanced,13,RUNX1(0.983)|ABL1(0.932)|PDGFRB(0.893)|NRAS(0.838)|JAK2(0.811)
EWSR1,EWS RNA binding protein 1,ENSG00000182944,2130,Q01844,CellAge,1,TRUE,Ewsr1,96.4939,TRUE,Cells_EBV-transformed_lymphocytes,278.52,278.52,Low tissue specificity,Low cell type specificity,22,DHX9(0.997)|HNRNPA1(0.951)|YBX1(0.943)|WT1(0.888)|PATZ1(0.88)
EZH2,enhancer of zeste 2 polycomb repressive complex 2 subunit,ENSG00000106462,2146,Q15910,CellAge|Reactome,2,TRUE,Ezh2,97.6032,TRUE,Cells_EBV-transformed_lymphocytes,54.7,54.7,Tissue enhanced,Cell type enhanced,115,BMI1(0.999)|DNMT1(0.999)|DNMT3A(0.999)|DNMT3B(0.999)|EED(0.999)
FANCD2,FA complementation group D2,ENSG00000144554,2177,Q9BXW9,CellAge,1,TRUE,Fancd2,74.9138,TRUE,Cells_EBV-transformed_lymphocytes,29.33,29.33,Tissue enhanced,Cell type enhanced,48,BRCA1(0.999)|BRCA2(0.999)|RAD51(0.998)|USP1(0.998)|BRIP1(0.997)
FAS,Fas cell surface death receptor,ENSG00000026103,355,P25445,GenAge|SenMayo,2,TRUE,Fas,48.9552,TRUE,Cells_EBV-transformed_lymphocytes,75.44,75.44,Low tissue specificity,Cell type enhanced,14,TNFRSF1A(0.999)|TNF(0.997)|TP53(0.877)|MAPK8(0.825)|SRC(0.807)
FASN,fatty acid synthase,ENSG00000169710,2194,P49327,CellAge,1,TRUE,Fasn,80.8841,TRUE,Adipose_Subcutaneous,374.99,374.99,Tissue enhanced,Cell type enriched,12,ACLY(0.994)|SREBF1(0.983)|PPARG(0.86)|HMGCR(0.82)|ESR1(0.792)
FASTK,Fas activated serine/threonine kinase,ENSG00000164896,10922,Q14296,CellAge,1,TRUE,Fastk,88.8889,TRUE,Pituitary,125.86,125.86,Low tissue specificity,Low cell type specificity,0,
FBXO22,F-box protein 22,ENSG00000167196,26263,Q8NEZ5,CellAge,1,TRUE,Fbxo22,92.3077,TRUE,Brain_Cerebellum,16.58,16.58,Low tissue specificity,Cell type enhanced,3,NFKBIA(0.901)|RBX1(0.778)|KDM4A(0.748)
FBXO31,F-box protein 31,ENSG00000103264,79791,Q5XUX0,CellAge,1,TRUE,Fbxo31,82.3748,TRUE,Brain_Cerebellar_Hemisphere,123.64,123.64,Tissue enhanced,Cell type enhanced,2,CCND1(0.985)|RBX1(0.853)
FBXO4,F-box protein 4,ENSG00000151876,26272,Q9UKT5,CellAge,1,TRUE,Fbxo4,87.5969,TRUE,Adipose_Subcutaneous,13.03,13.03,Low tissue specificity,Low cell type specificity,4,TERF1(0.996)|SKP2(0.958)|CCND1(0.956)|FBXW11(0.932)
FBXO5,F-box protein 5,ENSG00000112029,26271,Q9UKT4,CellAge,1,TRUE,Fbxo5,63.7584,TRUE,Cells_EBV-transformed_lymphocytes,43.8,43.8,Group enriched,Cell type enhanced,28,ANAPC4(0.999)|FZR1(0.998)|ANAPC2(0.989)|ANAPC10(0.986)|CDC23(0.985)
FBXW11,F-box and WD repeat domain containing 11,ENSG00000072803,23291,Q9UKB1,CellAge,1,TRUE,Fbxw11,93.2504,TRUE,Brain_Cerebellar_Hemisphere,56.35,56.35,Low tissue specificity,Low cell type specificity,20,RBX1(0.995)|CTNNB1(0.993)|NFKBIA(0.989)|SKP2(0.98)|FBXO5(0.965)
FDPS,farnesyl diphosphate synthase,ENSG00000160752,2224,P14324,CellAge,1,TRUE,Fdps,71.1217,TRUE,Cells_EBV-transformed_lymphocytes,239.22,239.22,Tissue enhanced,Cell type enhanced,7,HMGCR(0.967)|FNTB(0.953)|MVK(0.911)|PMVK(0.901)|DHCR24(0.795)
FEN1,flap structure-specific endonuclease 1,ENSG00000168496,2237,P39748,GenAge,1,TRUE,Fen1,96.5789,TRUE,Cells_EBV-transformed_lymphocytes,121.6,121.6,Tissue enhanced,Cell type enhanced,61,PCNA(0.999)|APEX1(0.998)|WRN(0.998)|POLD1(0.997)|POLB(0.987)
FERMT1,FERM domain containing kindlin 1,ENSG00000101311,55612,Q9BQL6,CellAge,1,TRUE,Fermt1,87.8877,TRUE,Adrenal_Gland,23.05,23.05,Tissue enhanced,Cell type enhanced,2,ILK(0.892)|FERMT2(0.743)
FERMT2,FERM domain containing kindlin 2,ENSG00000073712,10979,Q96AC1,CellAge,1,TRUE,Fermt2,98.2353,TRUE,Artery_Tibial,237.73,237.73,Low tissue specificity,Cell type enhanced,4,ILK(0.997)|CTNNB1(0.785)|ITGB3(0.761)|FERMT1(0.743)
FGF1,fibroblast growth factor 1,ENSG00000113578,2246,P05230,SenMayo,1,TRUE,Fgf1,95.4839,FALSE,Brain_Spinal_cord_cervical_c-1,225.99,225.99,Tissue enriched,Group enriched,24,FGFR1(0.999)|FGFR2(0.999)|FGFR3(0.999)|SYT1(0.978)|FGF2(0.962)
FGF2,fibroblast growth factor 2,ENSG00000138685,2247,P09038,SenMayo,1,TRUE,Fgf2,94.8387,FALSE,Cells_Cultured_fibroblasts,50.03,50.03,Low tissue specificity,Cell type enhanced,74,FGFR1(0.999)|FGFR2(0.999)|FGFR3(0.999)|KDR(0.998)|SDC1(0.997)
FGF21,fibroblast growth factor 21,ENSG00000105550,26291,Q9NSA1,CellAge|GenAge,2,TRUE,Fgf21,75.5981,FALSE,Liver,18.68,18.68,Tissue enriched,Group enriched,18,FGFR1(0.998)|KL(0.978)|FGFR2(0.977)|FGFR3(0.941)|PPARA(0.863)
FGF23,fibroblast growth factor 23,ENSG00000118972,8074,Q9GZV9,GenAge,1,TRUE,Fgf23,70.5179,TRUE,Heart_Atrial_Appendage,0.84,0.84,Tissue enhanced,Cell type enhanced,13,FGFR1(0.999)|KL(0.999)|FGFR2(0.986)|FGFR3(0.98)|CYP27B1(0.907)
FGF7,fibroblast growth factor 7,ENSG00000140285,2252,P21781,SenMayo,1,TRUE,Fgf7,94.3299,TRUE,Cervix_Ectocervix,64.95,64.95,Low tissue specificity,Cell type enhanced,40,FGFR1(0.999)|FGFR2(0.999)|EGF(0.992)|KL(0.99)|FGFR3(0.976)
FGFR1,fibroblast growth factor receptor 1,ENSG00000077782,2260,P11362,CellAge|GenAge,2,TRUE,Fgfr1,98.1752,TRUE,Artery_Aorta,144.82,144.82,Low tissue specificity,Cell type enhanced,46,FGF1(0.999)|FGF2(0.999)|FGF23(0.999)|FGF7(0.999)|KL(0.999)
FGFR2,fibroblast growth factor receptor 2,ENSG00000066468,2263,P21802,CellAge,1,TRUE,Fgfr2,97.5639,TRUE,Brain_Spinal_cord_cervical_c-1,130.14,130.14,Tissue enriched,Cell type enhanced,46,FGF1(0.999)|FGF2(0.999)|FGF7(0.999)|GRB2(0.993)|FGFR3(0.987)
FGFR3,fibroblast growth factor receptor 3,ENSG00000068078,2261,P22607,CellAge,1,TRUE,Fgfr3,92.6799,TRUE,Skin_Not_Sun_Exposed_Suprapubic,364.55,364.55,Tissue enhanced,Cell type enhanced,41,FGF1(0.999)|FGF2(0.999)|FGFR2(0.987)|GRB2(0.984)|HRAS(0.982)
FIS1,"fission, mitochondrial 1",ENSG00000214253,51024,Q9Y3D6,CellAge,1,TRUE,Fis1,96.0526,TRUE,Brain_Spinal_cord_cervical_c-1,231.05,231.05,Low tissue specificity,Cell type enhanced,8,MARCHF5(0.965)|PINK1(0.931)|OPA1(0.915)|PRKN(0.849)|PEX19(0.848)
FLT1,fms related receptor tyrosine kinase 1,ENSG00000102755,2321,P17948,CellAge|GenAge,2,TRUE,Flt1,81.6891,TRUE,Thyroid,54.17,54.17,Tissue enriched,Cell type enhanced,42,PGF(0.999)|VEGFC(0.999)|KDR(0.994)|FGF2(0.993)|ANGPT1(0.984)
FNTB,"farnesyltransferase, CAAX box, subunit beta",ENSG00000257365,2342,P49356,CellAge,1,TRUE,Fntb,88.1007,TRUE,Brain_Spinal_cord_cervical_c-1,145.69,145.69,Tissue enriched,Cell type enhanced,4,ZMPSTE24(0.963)|FDPS(0.953)|HRAS(0.783)|DYRK1A(0.742)
FOS,"Fos proto-oncogene, AP-1 transcription factor subunit",ENSG00000170345,2353,P01100,CellAge|GenAge|Reactome,3,TRUE,Fos,91.3158,TRUE,Fallopian_Tube,1112.22,1112.22,Low tissue specificity,Cell type enhanced,95,ESR1(0.999)|JUN(0.999)|JUNB(0.999)|JUND(0.999)|CREB1(0.998)
FOXA1,forkhead box A1,ENSG00000129514,3169,P55317,CellAge,1,TRUE,Foxa1,94.9153,TRUE,Prostate,71.41,71.41,Tissue enhanced,Cell type enhanced,23,ESR1(0.998)|AR(0.996)|HDAC7(0.976)|EP300(0.933)|PGR(0.887)
FOXD1,forkhead box D1,ENSG00000251493,2297,Q16676,CellAge,1,TRUE,Foxd1,81.2903,TRUE,Nerve_Tibial,33.86,33.86,Low tissue specificity,Cell type enhanced,1,WT1(0.77)
FOXM1,forkhead box M1,ENSG00000111206,2305,Q08050,CellAge|GenAge,2,TRUE,Foxm1,79.6855,TRUE,Cells_EBV-transformed_lymphocytes,51.69,51.69,Tissue enhanced,Cell type enhanced,51,MYBL2(0.998)|PLK1(0.995)|CTNNB1(0.994)|CDK1(0.991)|CCNB1(0.988)
FOXO1,forkhead box O1,ENSG00000150907,2308,Q12778,CellAge|GenAge,2,TRUE,Foxo1,92.5191,TRUE,Ovary,110.65,110.65,Tissue enhanced,Cell type enhanced,97,AKT1(0.999)|PPARGC1A(0.999)|SIRT1(0.999)|ATG7(0.998)|CREBBP(0.993)
FOXO3,forkhead box O3,ENSG00000118689,2309,O43524,CellAge|GenAge,2,TRUE,Foxo3,94.6508,FALSE,Artery_Tibial,71.81,71.81,Low tissue specificity,Cell type enhanced,83,CDK2(0.999)|SIRT1(0.999)|AKT1(0.998)|CTNNB1(0.998)|TP53(0.998)
FOXO4,forkhead box O4,ENSG00000184481,4303,P98177,CellAge|GenAge,2,TRUE,Foxo4,88.3168,TRUE,Brain_Spinal_cord_cervical_c-1,56.24,56.24,Tissue enhanced,Group enriched,36,TP53(0.995)|AKT1(0.992)|CREBBP(0.984)|EP300(0.983)|AKT3(0.953)
FOXP1,forkhead box P1,ENSG00000114861,27086,Q9H334,CellAge,1,TRUE,Foxp1,83.8996,FALSE,Esophagus_Muscularis,32.43,32.43,Low tissue specificity,Cell type enhanced,8,SOX2(0.893)|POU5F1(0.862)|KLF4(0.86)|NANOG(0.855)|NCOR2(0.807)
FOXP3,forkhead box P3,ENSG00000049768,50943,Q9BZS1,CellAge,1,TRUE,Foxp3,86.3109,FALSE,Testis,2.84,2.84,Tissue enhanced,Cell type enhanced,34,RUNX1(0.999)|KAT5(0.992)|IL2(0.991)|HIF1A(0.988)|STAT3(0.984)
FOXQ1,forkhead box Q1,ENSG00000164379,94234,Q9C009,CellAge,1,TRUE,Foxq1,76.1787,TRUE,Skin_Sun_Exposed_Lower_leg,44.9,44.9,Tissue enhanced,Cell type enhanced,0,
FSCN1,fascin actin-bundling protein 1,ENSG00000075618,6624,Q16658,CellAge,1,TRUE,Fscn1,96.5517,TRUE,Cells_Cultured_fibroblasts,281.82,281.82,Low tissue specificity,Cell type enhanced,5,CTNNB1(0.858)|ANGPTL4(0.844)|LCP1(0.816)|AKT1(0.799)|STAT3(0.742)
FXN,frataxin,ENSG00000165060,2395,Q16595,CellAge,1,TRUE,Fxn,70.4762,TRUE,Ovary,12.49,12.49,Low tissue specificity,Cell type enhanced,4,HSPA9(0.954)|APTX(0.841)|HSPD1(0.736)|CACNA1A(0.727)
FXR1,FMR1 autosomal homolog 1,ENSG00000114416,8087,P51114,CellAge,1,TRUE,Fxr1,98.0676,TRUE,Muscle_Skeletal,96.31,96.31,Group enriched,Cell type enhanced,9,AGO2(0.996)|DICER1(0.959)|CPEB1(0.894)|YBX1(0.892)|AGO1(0.848)
FZR1,fizzy and cell division cycle 20 related 1,ENSG00000105325,51343,Q9UM11,Reactome,1,TRUE,Fzr1,98.3773,TRUE,Brain_Cerebellum,72.46,72.46,Low tissue specificity,Cell type enhanced,45,ANAPC2(0.999)|ANAPC4(0.999)|ANAPC5(0.999)|ANAPC7(0.999)|CDC16(0.999)
G6PD,glucose-6-phosphate dehydrogenase,ENSG00000160211,2539,P11413,CellAge,1,TRUE,G6pdx,93.7864,TRUE,Testis,146.03,146.03,Low tissue specificity,Cell type enhanced,11,TP53(0.986)|GAPDH(0.97)|HK3(0.939)|GSR(0.932)|NADK(0.917)
GADD45G,growth arrest and DNA damage inducible gamma,ENSG00000130222,10912,O95257,CellAge,1,TRUE,Gadd45g,96.8553,TRUE,Artery_Tibial,181.27,181.27,Tissue enhanced,Cell type enriched,5,CCNB1(0.986)|CDK1(0.982)|PCNA(0.96)|TP53(0.937)|CDKN1A(0.729)
GAPDH,glyceraldehyde-3-phosphate dehydrogenase,ENSG00000111640,2597,P04406,CellAge,1,TRUE,Gapdh,93.4328,TRUE,Cells_EBV-transformed_lymphocytes,6385.15,6385.15,Group enriched,Cell type enhanced,116,ALDOA(0.999)|ENO1(0.998)|SIAH1(0.997)|HTT(0.993)|HSPA8(0.986)
GATA4,GATA binding protein 4,ENSG00000136574,2626,P43694,CellAge,1,TRUE,Gata4,91.4221,TRUE,Ovary,144.05,144.05,Tissue enhanced,Cell type enhanced,14,SRF(0.991)|EP300(0.973)|SQSTM1(0.949)|WT1(0.935)|RHOA(0.931)
GCLC,glutamate-cysteine ligase catalytic subunit,ENSG00000001084,2729,P48506,GenAge,1,TRUE,Gclc,94.5055,TRUE,Bladder,33.02,33.02,Tissue enhanced,Cell type enhanced,12,GCLM(0.999)|GSS(0.995)|NFE2L2(0.966)|GGCT(0.922)|CTH(0.906)
GCLM,glutamate-cysteine ligase modifier subunit,ENSG00000023909,2730,P48507,GenAge,1,TRUE,Gclm,96.3504,TRUE,Cells_Cultured_fibroblasts,23.44,23.44,Tissue enhanced,Cell type enhanced,9,GCLC(0.999)|GSS(0.989)|NFE2L2(0.951)|NQO1(0.949)|KEAP1(0.932)
GDF11,growth differentiation factor 11,ENSG00000135414,10220,O95390,GenAge,1,TRUE,Gdf11,99.0172,FALSE,Brain_Spinal_cord_cervical_c-1,13.9,13.9,Tissue enhanced,Cell type enriched,4,TGFBR1(0.999)|ACVR1B(0.932)|WIF1(0.833)|MNX1(0.765)
GDF15,growth differentiation factor 15,ENSG00000130513,9518,Q99988,CellAge|SenMayo,2,TRUE,Gdf15,57.7922,FALSE,Kidney_Cortex,120.11,120.11,Tissue enhanced,Cell type enhanced,3,TGFBR2(0.96)|RET(0.958)|TP53(0.762)
GEM,GTP binding protein overexpressed in skeletal muscle,ENSG00000164949,2669,P55040,SenMayo,1,TRUE,Gem,95.6081,TRUE,Artery_Aorta,265.38,265.38,Tissue enhanced,Cell type enhanced,0,
GEMIN2,gem nuclear organelle associated protein 2,ENSG00000092208,8487,O14893,CellAge,1,TRUE,Gemin2,94.4238,TRUE,Cells_EBV-transformed_lymphocytes,25.17,25.17,Low tissue specificity,Cell type enhanced,0,
GGCT,gamma-glutamylcyclotransferase,ENSG00000006625,79017,O75223,CellAge,1,TRUE,Ggct,81.9149,TRUE,Esophagus_Mucosa,69.47,69.47,Low tissue specificity,Cell type enhanced,4,GSS(0.926)|GCLC(0.922)|GCLM(0.921)|CTH(0.806)
GH1,growth hormone 1,ENSG00000259384,2688,P01241,GenAge,1,TRUE,Gh,65.4378,TRUE,Pituitary,53058.8,53058.8,Tissue enriched,Cell type enriched,12,GHR(0.999)|GHRH(0.964)|LEP(0.949)|GHRHR(0.918)|IGF1(0.91)
GHR,growth hormone receptor,ENSG00000112964,2690,P10912,GenAge,1,TRUE,Ghr,69.5925,TRUE,Adipose_Subcutaneous,51.37,51.37,Tissue enhanced,Group enriched,24,GH1(0.999)|JAK2(0.999)|SOCS2(0.993)|STAT5B(0.977)|IGF1(0.956)
GHRH,growth hormone releasing hormone,ENSG00000291972,2691,P01286,GenAge,1,FALSE,,,FALSE,,,,,,10,GHRHR(0.999)|GH1(0.964)|SST(0.964)|IGF1(0.916)|GHR(0.84)
GHRHR,growth hormone releasing hormone receptor,ENSG00000106128,2692,Q02643,GenAge,1,TRUE,Ghrhr,76.5957,TRUE,Pituitary,294.17,294.17,Tissue enriched,Cell type enriched,7,GHRH(0.999)|PROP1(0.927)|GH1(0.918)|POU1F1(0.884)|GHR(0.843)
GJA1,gap junction protein alpha 1,ENSG00000152661,2697,P17302,CellAge,1,TRUE,Gja1,97.3822,TRUE,Skin_Not_Sun_Exposed_Suprapubic,485.12,485.12,Low tissue specificity,Cell type enhanced,14,SRC(0.998)|CAV1(0.965)|MAPK3(0.947)|MAPK1(0.943)|MAPK7(0.941)
GKN1,gastrokine 1,ENSG00000169605,56287,Q9NS71,CellAge,1,TRUE,Gkn1,63.7838,FALSE,Stomach,1514.92,1514.92,Tissue enriched,Cell type enriched,0,
GLI1,GLI family zinc finger 1,ENSG00000111087,2735,P08151,CellAge,1,TRUE,Gli1,85.8047,TRUE,Nerve_Tibial,46.22,46.22,Tissue enhanced,Group enriched,13,SPOP(0.99)|FBXW11(0.957)|ARRB1(0.93)|BMI1(0.867)|STAT3(0.859)
GMFG,glia maturation factor gamma,ENSG00000130755,9535,O60234,SenMayo,1,TRUE,Gmfg,93.662,FALSE,Whole_Blood,274.5,274.5,Tissue enhanced,Cell type enhanced,1,ARPC1B(0.927)
GMNN,geminin DNA replication inhibitor,ENSG00000112312,51053,O75496,CellAge,1,TRUE,Gmnn,77.512,TRUE,Cells_EBV-transformed_lymphocytes,41.82,41.82,Tissue enhanced,Cell type enhanced,10,SPOP(0.946)|CDC6(0.905)|CCNA2(0.882)|CDK1(0.867)|FBXO5(0.867)
GMPS,guanosine monophosphate synthase,ENSG00000163655,8833,P49915,CellAge,1,TRUE,Gmps,97.9798,TRUE,Testis,50.81,50.81,Tissue enhanced,Cell type enhanced,5,DKC1(0.866)|GAR1(0.823)|MTHFD2(0.778)|RRM1(0.748)|PES1(0.718)
GNG11,G protein subunit gamma 11,ENSG00000127920,2791,P61952,CellAge,1,TRUE,Gng11,100,TRUE,Ovary,124.13,124.13,Low tissue specificity,Cell type enriched,1,ADCY5(0.713)
GNMT,glycine N-methyltransferase,ENSG00000124713,27232,Q14749,CellAge,1,TRUE,Gnmt,91.5254,TRUE,Pancreas,270.45,270.45,Group enriched,Cell type enriched,3,DAO(0.91)|ARRB1(0.78)|CBS(0.712)
GPC3,glypican 3,ENSG00000147257,2719,P51654,CellAge,1,TRUE,Gpc3,93.9655,TRUE,Lung,201.35,201.35,Tissue enriched,Cell type enhanced,9,IGF2(0.993)|WNT5A(0.96)|WNT2(0.927)|WNT7B(0.919)|WNT16(0.918)
GPX1,glutathione peroxidase 1,ENSG00000233276,2876,P07203,GenAge,1,TRUE,Gpx1,85.2217,TRUE,Whole_Blood,541.5,541.5,Low tissue specificity,Cell type enhanced,0,
GPX4,glutathione peroxidase 4,ENSG00000167468,2879,P36969,GenAge,1,TRUE,Gpx4,93.401,TRUE,Testis,1682.13,1682.13,Low tissue specificity,Cell type enriched,12,GSR(0.98)|GRSF1(0.964)|HSPA5(0.952)|GSTP1(0.945)|GSS(0.944)
GRB2,growth factor receptor bound protein 2,ENSG00000177885,2885,P62993,GenAge,1,TRUE,Grb2,99.5392,TRUE,Cells_EBV-transformed_lymphocytes,186.05,186.05,Low tissue specificity,Cell type enhanced,77,ABL1(0.999)|CD28(0.999)|EGFR(0.999)|ERBB2(0.999)|IRS1(0.999)
GRIK2,glutamate ionotropic receptor kainate type subunit 2,ENSG00000164418,2898,Q13002,CellAge,1,TRUE,Grik2,99.0088,TRUE,Brain_Cerebellar_Hemisphere,95.48,95.48,Group enriched,Cell type enhanced,1,UBE2I(0.842)
GRK4,G protein-coupled receptor kinase 4,ENSG00000125388,2868,P32298,CellAge,1,TRUE,Grk4,74.9135,TRUE,Testis,59.75,59.75,Tissue enhanced,Cell type enhanced,1,ARRB1(0.937)
GRK6,G protein-coupled receptor kinase 6,ENSG00000198055,2870,P43250,CellAge,1,TRUE,Grk6,96.7014,TRUE,Whole_Blood,138.58,138.58,Tissue enhanced,Cell type enhanced,2,ARRB1(0.95)|CXCR2(0.885)
GRN,granulin precursor,ENSG00000030582,2896,P28799,CellAge|GenAge,2,TRUE,Grn,74.8735,TRUE,Esophagus_Mucosa,503.84,503.84,Low tissue specificity,Cell type enhanced,5,MAPT(0.885)|CTSD(0.866)|TNFRSF1A(0.803)|TNFRSF1B(0.783)|VCP(0.762)
GRPR,gastrin releasing peptide receptor,ENSG00000126010,2925,P30550,CellAge,1,TRUE,Grpr,90.1042,TRUE,Pancreas,5.33,5.33,Tissue enriched,Cell type enhanced,1,SST(0.74)
GRSF1,G-rich RNA sequence binding factor 1,ENSG00000132463,2926,Q12849,CellAge,1,TRUE,Grsf1,90,FALSE,Muscle_Skeletal,49.54,49.54,Tissue enhanced,Low cell type specificity,2,GPX4(0.964)|PNPT1(0.783)
GSK3A,glycogen synthase kinase 3 alpha,ENSG00000105723,2931,P49840,CellAge|GenAge,2,TRUE,Gsk3a,95.0311,TRUE,Brain_Cerebellar_Hemisphere,87.41,87.41,Low tissue specificity,Cell type enhanced,12,CTNNB1(0.996)|AKT1(0.993)|CSNK1A1(0.991)|GSK3B(0.98)|AKT3(0.937)
GSK3B,glycogen synthase kinase 3 beta,ENSG00000082701,2932,P49841,CellAge|GenAge,2,TRUE,Gsk3b,99.0476,TRUE,Brain_Cerebellar_Hemisphere,35.75,35.75,Low tissue specificity,Cell type enhanced,77,CSNK1A1(0.999)|CTNNB1(0.999)|MAPT(0.999)|AKT1(0.996)|MYC(0.996)
GSR,glutathione-disulfide reductase,ENSG00000104687,2936,P00390,GenAge,1,TRUE,Gsr,81.0345,TRUE,Cells_Cultured_fibroblasts,67.99,67.99,Low tissue specificity,Cell type enhanced,16,GPX4(0.98)|GSS(0.961)|GSTP1(0.952)|GSTA4(0.939)|G6PD(0.932)
GSS,glutathione synthetase,ENSG00000100983,2937,P48637,GenAge,1,TRUE,Gss,88.6076,TRUE,Cells_Cultured_fibroblasts,80.52,80.52,Low tissue specificity,Cell type enhanced,7,GCLC(0.995)|GCLM(0.989)|GSR(0.961)|GPX4(0.944)|GSTP1(0.934)
GSTA4,glutathione S-transferase alpha 4,ENSG00000170899,2941,O15217,GenAge,1,FALSE,,,TRUE,Adrenal_Gland,290.61,290.61,Tissue enhanced,Cell type enhanced,4,GSR(0.939)|GPX4(0.938)|GSS(0.924)|GSTP1(0.731)
GSTP1,glutathione S-transferase pi 1,ENSG00000084207,2950,P09211,GenAge,1,TRUE,Gstp1,85.2381,FALSE,Esophagus_Mucosa,2342.02,2342.02,Tissue enhanced,Cell type enhanced,12,MAPK8(0.974)|GSR(0.952)|GPX4(0.945)|GSS(0.934)|JUN(0.927)
GTF2H2,general transcription factor IIH subunit 2,ENSG00000145736,2966,Q13888,GenAge,1,TRUE,Gtf2h2,97.2152,TRUE,Cells_EBV-transformed_lymphocytes,2.94,2.94,Low tissue specificity,Cell type enhanced,16,CDK7(0.999)|ERCC2(0.999)|ERCC3(0.999)|ERCC5(0.998)|TBP(0.991)
GTSE1,G2 and S-phase expressed 1,ENSG00000075218,51512,Q9NYZ3,CellAge,1,TRUE,Gtse1,56.0217,TRUE,Cells_EBV-transformed_lymphocytes,40.27,40.27,Tissue enhanced,Cell type enhanced,15,PLK1(0.982)|TP53(0.933)|HJURP(0.889)|BIRC5(0.852)|CDKN1A(0.844)
H1-0,H1.0 linker histone,ENSG00000189060,3005,P07305,Reactome,1,TRUE,H1f0,94.8454,TRUE,Skin_Sun_Exposed_Lower_leg,392.09,392.09,Tissue enhanced,Cell type enriched,21,H2BC21(0.996)|H2AC18(0.995)|H2AC20(0.995)|CDK2(0.979)|CDK1(0.95)
H1-1,"H1.1 linker histone, cluster member",ENSG00000124610,3024,Q02539,Reactome,1,TRUE,H1f1,79.0698,FALSE,Testis,0.29,0.29,Not detected,Cell type enhanced,13,CDK2(0.995)|H2AC20(0.995)|H2AC18(0.994)|H2BC21(0.987)|H1-5(0.945)
H1-2,"H1.2 linker histone, cluster member",ENSG00000187837,3006,P16403,Reactome,1,TRUE,H1f2,88.2629,FALSE,Cells_EBV-transformed_lymphocytes,229.52,229.52,Low tissue specificity,Cell type enhanced,13,H2AC18(0.953)|H2BC21(0.928)|H2BC5(0.89)|H2BC4(0.877)|H2BC12(0.876)
H1-3,"H1.3 linker histone, cluster member",ENSG00000124575,3007,P16402,Reactome,1,TRUE,H1f3,87.7828,TRUE,Vagina,3.03,3.03,Tissue enhanced,Cell type enhanced,7,H1-4(0.95)|H1-5(0.911)|H1-2(0.828)|H2AC20(0.826)|H2BC21(0.822)
H1-4,"H1.4 linker histone, cluster member",ENSG00000168298,3008,P10412,Reactome,1,TRUE,H1f4,94.0639,TRUE,Vagina,3.91,3.91,Tissue enriched,Cell type enhanced,15,KDM4A(0.952)|H1-3(0.95)|H3C1(0.931)|H4C1(0.929)|H2BC12(0.927)
H1-5,"H1.5 linker histone, cluster member",ENSG00000184357,3009,P16401,Reactome,1,TRUE,H1f5,90.708,TRUE,Cells_EBV-transformed_lymphocytes,0.87,0.87,Group enriched,Group enriched,13,H2AC18(0.991)|H2AC20(0.991)|H2BC21(0.982)|H1-1(0.945)|CDK2(0.933)
H2AB1,H2A.B variant histone 1,ENSG00000274183,474382,P0C5Y9,Reactome,1,TRUE,H2ab3,54.7826,FALSE,Testis,4.88,4.88,Tissue enriched,Cell type enhanced,5,H2BC21(0.876)|CENPA(0.827)|H2BC1(0.767)|H3-4(0.733)|HDAC2(0.705)
H2AC14,H2A clustered histone 14,ENSG00000276368,8331,Q99878,Reactome,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,1.03,1.03,Tissue enriched,Cell type enhanced,22,H2BC11(0.971)|H2BC12(0.968)|H2AC4(0.961)|H4C1(0.955)|H2AC6(0.944)
H2AC18,H2A clustered histone 18,ENSG00000288825,8337,Q6FI13,Reactome,1,TRUE,H2ac18,100,FALSE,,,,Tissue enhanced,Cell type enhanced,83,H2BC21(0.999)|H3-4(0.999)|TP53BP1(0.999)|CENPA(0.998)|H2BC12(0.997)
H2AC20,H2A clustered histone 20,ENSG00000184260,8338,Q16777,Reactome,1,TRUE,H2ac20,100,TRUE,Cervix_Ectocervix,8.38,8.38,Tissue enriched,Cell type enhanced,85,H2BC21(0.999)|H3-4(0.999)|H1-0(0.995)|H1-1(0.995)|H2BC1(0.995)
H2AC4,H2A clustered histone 4,ENSG00000278463,8335,P04908,Reactome,1,FALSE,,,FALSE,Testis,1.47,1.47,Tissue enhanced,Cell type enhanced,35,H4C1(0.993)|H3C1(0.986)|H2BC11(0.976)|H2BC3(0.973)|H3C15(0.972)
H2AC6,H2A clustered histone 6,ENSG00000180573,8334,Q93077,Reactome,1,FALSE,,,FALSE,Whole_Blood,168.88,168.88,Low tissue specificity,Cell type enriched,36,H2BC5(0.998)|H2BC12(0.994)|H2BC21(0.994)|H2BC9(0.992)|H2BC17(0.99)
H2AC7,H2A clustered histone 7,ENSG00000196866,3013,P20671,Reactome,1,FALSE,,,FALSE,Whole_Blood,19.65,19.65,Low tissue specificity,Cell type enriched,19,H2BC17(0.992)|H2BC9(0.991)|H2BC4(0.987)|H2BC21(0.985)|H2BC3(0.985)
H2AJ,H2A.J histone,ENSG00000246705,55766,Q9BTM1,Reactome,1,TRUE,H2aj,96.124,TRUE,Testis,225.22,225.22,Tissue enhanced,Cell type enhanced,18,H2BC21(0.981)|H2BC5(0.979)|H2BC17(0.976)|H2BC4(0.974)|H2BC9(0.974)
H2AX,H2A.X variant histone,ENSG00000188486,3014,P16104,GenAge|Reactome,2,TRUE,H2ax,97.2028,TRUE,Cells_EBV-transformed_lymphocytes,149.99,149.99,Low tissue specificity,Cell type enhanced,94,BRCA1(0.999)|MDC1(0.999)|TP53BP1(0.999)|ATM(0.998)|H2BC21(0.998)
H2AZ2,H2A.Z variant histone 2,ENSG00000105968,94239,Q71UI9,Reactome,1,TRUE,H2az2,100,TRUE,Brain_Cerebellar_Hemisphere,152.24,152.24,Low tissue specificity,Cell type enhanced,28,H2BC21(0.989)|H4C1(0.95)|EP400(0.947)|H3C1(0.944)|H2BC17(0.894)
H2BC1,H2B clustered histone 1,ENSG00000146047,255626,Q96A08,Reactome,1,TRUE,H2bc1,94.4882,TRUE,Testis,11.26,11.26,Tissue enriched,Not detected,30,H2AC20(0.995)|H2AC7(0.965)|H4C1(0.942)|H2AC4(0.936)|H3-4(0.932)
H2BC11,H2B clustered histone 11,ENSG00000124635,8970,P06899,Reactome,1,TRUE,H2bc21,97.619,FALSE,Testis,33.91,33.91,Tissue enhanced,Cell type enriched,55,H2AC6(0.988)|H3-4(0.986)|H2AX(0.98)|H2AC4(0.976)|H4C1(0.975)
H2BC12,H2B clustered histone 12,ENSG00000197903,85236,O60814,Reactome,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,200.17,200.17,Low tissue specificity,Cell type enhanced,46,H2AC18(0.997)|H2AC6(0.994)|H2AC20(0.992)|H3-4(0.991)|H2AX(0.976)
H2BC12L,H2B clustered histone 12 like,ENSG00000234289,54145,P57053,Reactome,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,0.09,0.09,Tissue enhanced,Not detected,0,
H2BC13,H2B clustered histone 13,ENSG00000185130,8340,Q99880,Reactome,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,1.26,1.26,Tissue enriched,Cell type enhanced,21,H3-4(0.94)|H2BC1(0.913)|H2AC20(0.909)|H2AC18(0.889)|H2AC14(0.822)
H2BC14,H2B clustered histone 14,ENSG00000273703,8342,Q99879,Reactome,1,TRUE,H2bc9,96.8254,FALSE,Cells_EBV-transformed_lymphocytes,1.14,1.14,Tissue enhanced,Cell type enhanced,33,H2AC6(0.988)|CENPA(0.983)|H2AC7(0.976)|H2BC3(0.972)|H2BC17(0.971)
H2BC15,H2B clustered histone 15,ENSG00000233822,8341,Q99877,Reactome,1,FALSE,,,FALSE,Testis,1.59,1.59,Low tissue specificity,Cell type enhanced,28,H2AC6(0.988)|CENPA(0.983)|H2AC7(0.974)|H2AJ(0.968)|H2BC17(0.963)
H2BC17,H2B clustered histone 17,ENSG00000274641,8348,P23527,Reactome,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,3.71,3.71,Tissue enhanced,Cell type enhanced,36,H2AC7(0.992)|H2AC6(0.99)|CENPA(0.985)|DNMT3B(0.984)|H2BC3(0.979)
H2BC21,H2B clustered histone 21,ENSG00000184678,8349,Q16778,Reactome,1,FALSE,,,FALSE,Prostate,151.6,151.6,Low tissue specificity,Cell type enhanced,106,H2AC18(0.999)|H2AC20(0.999)|H3-4(0.999)|H2AX(0.998)|H1-0(0.996)
H2BC26,H2B clustered histone 26,ENSG00000285449,128312,Q8N257,Reactome,1,FALSE,,,FALSE,,,,,,0,
H2BC3,H2B clustered histone 3,ENSG00000276410,3018,P33778,Reactome,1,TRUE,H2bc3,97.619,FALSE,Testis,2.07,2.07,Tissue enhanced,Cell type enhanced,45,H2AC20(0.99)|H2AC6(0.987)|H2AC7(0.985)|H2BC17(0.979)|H2AC4(0.973)
H2BC4,H2B clustered histone 4,ENSG00000180596,8347,P62807,Reactome,1,FALSE,,,FALSE,Whole_Blood,31.11,31.11,Low tissue specificity,Cell type enhanced,43,H2AC18(0.996)|H2AC20(0.991)|H2AC6(0.99)|H2AC7(0.987)|H2BC21(0.977)
H2BC5,H2B clustered histone 5,ENSG00000158373,3017,P58876,Reactome,1,TRUE,H2bc14,100,FALSE,Prostate,108.43,108.43,Low tissue specificity,Cell type enhanced,31,H2AC6(0.998)|CENPA(0.983)|H2AC7(0.983)|H2AJ(0.979)|H2BC9(0.977)
H2BC9,H2B clustered histone 9,ENSG00000275713,8345,Q93079,Reactome,1,FALSE,,,FALSE,Vagina,3.85,3.85,Tissue enhanced,Cell type enhanced,31,H2AC6(0.992)|H2AC7(0.991)|CENPA(0.983)|H2BC5(0.977)|H2BC4(0.976)
H3-3A,H3.3 histone A,ENSG00000163041,3020,P84243,Reactome,1,TRUE,H3f3a,100,TRUE,Whole_Blood,120.95,120.95,Low tissue specificity,Cell type enhanced,35,ATRX(0.976)|ASF1A(0.963)|CBX5(0.959)|H2BC21(0.941)|H4C1(0.94)
H3-4,"H3.4 histone, cluster member",ENSG00000168148,8290,Q16695,Reactome,1,TRUE,H3f4,97.7941,FALSE,Testis,5.68,5.68,Tissue enriched,Not detected,146,CBX5(0.999)|H2AC18(0.999)|H2AC20(0.999)|H2BC21(0.999)|DNMT3A(0.998)
H3C1,H3 clustered histone 1,ENSG00000275714,8350,P68431,Reactome,1,TRUE,H3c10,100,FALSE,Testis,5.31,5.31,Group enriched,Cell type enriched,75,EP300(0.998)|ASF1A(0.991)|CREBBP(0.989)|CBX5(0.988)|H4C1(0.987)
H3C15,H3 clustered histone 15,ENSG00000203852,333932,Q71DI3,Reactome,1,TRUE,H3c4,100,TRUE,Fallopian_Tube,0.04,0.04,Tissue enhanced,Not detected,65,H2AC4(0.972)|H2BC17(0.968)|H4C1(0.968)|H3C1(0.962)|H2AC20(0.953)
H4C1,H4 clustered histone 1,ENSG00000278637,8359,P62805,Reactome,1,FALSE,,,TRUE,Brain_Cerebellar_Hemisphere,0.97,0.97,Tissue enhanced,Cell type enhanced,66,H2AC4(0.993)|H3C1(0.987)|H2BC11(0.975)|H2AC20(0.974)|H2AC18(0.972)
HAS1,hyaluronan synthase 1,ENSG00000105509,3036,Q92839,CellAge,1,TRUE,Has1,96.1872,TRUE,Adipose_Visceral_Omentum,43.16,43.16,Tissue enhanced,Group enriched,0,
HAUS4,HAUS augmin like complex subunit 4,ENSG00000092036,54930,Q9H6D7,CellAge,1,TRUE,Haus4,78.2369,TRUE,Ovary,92.95,92.95,Low tissue specificity,Cell type enhanced,0,
HBP1,HMG-box transcription factor 1,ENSG00000105856,26959,O60381,CellAge|GenAge,2,TRUE,Hbp1,95.1362,TRUE,Artery_Tibial,53.87,53.87,Low tissue specificity,Cell type enriched,1,SIN3A(0.964)
HDAC1,histone deacetylase 1,ENSG00000116478,3065,Q13547,CellAge|GenAge,2,TRUE,Hdac1,99.3776,TRUE,Cells_EBV-transformed_lymphocytes,226.13,226.13,Low tissue specificity,Low cell type specificity,157,DNMT1(0.999)|DNMT3B(0.999)|E2F1(0.999)|EHMT2(0.999)|EP300(0.999)
HDAC2,histone deacetylase 2,ENSG00000196591,3066,Q92769,CellAge|GenAge,2,TRUE,Hdac2,99.3852,FALSE,Testis,27.78,27.78,Low tissue specificity,Low cell type specificity,108,DNMT1(0.999)|EZH2(0.999)|HDAC1(0.999)|KDM1A(0.999)|RBBP4(0.999)
HDAC3,histone deacetylase 3,ENSG00000171720,8841,O15379,CellAge|GenAge,2,TRUE,Hdac3,99.7664,FALSE,Cells_EBV-transformed_lymphocytes,114.92,114.92,Low tissue specificity,Low cell type specificity,59,NCOR1(0.999)|NCOR2(0.999)|EZH2(0.989)|SIN3A(0.987)|RBBP4(0.982)
HDAC4,histone deacetylase 4,ENSG00000068024,9759,P56524,CellAge,1,TRUE,Hdac4,92.9293,TRUE,Colon_Sigmoid,50.92,50.92,Tissue enhanced,Cell type enhanced,48,NCOR1(0.999)|NCOR2(0.999)|HSP90AA1(0.975)|MEF2A(0.973)|BCL6(0.966)
HDAC7,histone deacetylase 7,ENSG00000061273,51564,Q8WUI4,CellAge,1,TRUE,Hdac7,84.0565,TRUE,Uterus,126.68,126.68,Low tissue specificity,Low cell type specificity,40,KAT5(0.98)|FOXA1(0.976)|MEF2A(0.959)|NCOR1(0.959)|FOXP3(0.953)
HELLS,"helicase, lymphoid specific",ENSG00000119969,3070,Q9NRZ9,CellAge|GenAge,2,TRUE,Hells,89.4988,TRUE,Cells_EBV-transformed_lymphocytes,30.71,30.71,Tissue enhanced,Cell type enhanced,11,DNMT3B(0.945)|CDC6(0.816)|RAD51(0.812)|DNMT3A(0.808)|HDAC1(0.785)
HEPACAM,hepatic and glial cell adhesion molecule,ENSG00000165478,220296,Q14CZ8,CellAge,1,TRUE,Hepacam,94.4712,TRUE,Brain_Cortex,57.6,57.6,Tissue enhanced,Cell type enhanced,0,
HESX1,HESX homeobox 1,ENSG00000163666,8820,Q9UBX0,GenAge,1,TRUE,Hesx1,79.4595,FALSE,Testis,9.71,9.71,Low tissue specificity,Cell type enhanced,3,POU1F1(0.95)|SOX2(0.727)|NCOR1(0.712)
HGF,hepatocyte growth factor,ENSG00000019991,3082,P14210,SenMayo,1,TRUE,Hgf,90.6593,TRUE,Lung,16.1,16.1,Tissue enriched,Cell type enhanced,42,MET(0.999)|IL7(0.991)|EGFR(0.98)|KDR(0.966)|FGF2(0.955)
HIC1,HIC ZBTB transcriptional repressor 1,ENSG00000177374,3090,Q14526,GenAge,1,TRUE,Hic1,95.3782,TRUE,Ovary,30.14,30.14,Low tissue specificity,Cell type enhanced,5,SIRT1(0.876)|UBE2I(0.767)|DNMT1(0.761)|RASSF1(0.72)|CTNNB1(0.716)
HIF1A,hypoxia inducible factor 1 subunit alpha,ENSG00000100644,3091,Q16665,CellAge|GenAge,2,TRUE,Hif1a,90.4358,TRUE,Cells_Cultured_fibroblasts,503.88,503.88,Tissue enhanced,Cell type enhanced,115,CREBBP(0.999)|EGLN1(0.999)|EP300(0.999)|HSP90AA1(0.999)|TP53(0.999)
HIPK2,homeodomain interacting protein kinase 2,ENSG00000064393,28996,Q9H2X6,CellAge,1,TRUE,Hipk2,96.7446,TRUE,Brain_Spinal_cord_cervical_c-1,150.84,150.84,Tissue enriched,Cell type enhanced,16,TP53(0.999)|UBE2I(0.966)|PIN1(0.965)|SIAH1(0.942)|TP53INP1(0.941)
HIRA,histone cell cycle regulator,ENSG00000100084,7290,P54198,CellAge|Reactome,2,TRUE,Hira,95.7719,TRUE,Thyroid,145.24,145.24,Low tissue specificity,Low cell type specificity,6,ASF1A(0.999)|CABIN1(0.999)|UBN1(0.999)|H3-3A(0.731)|H3C1(0.712)
HIVEP1,HIVEP zinc finger 1,ENSG00000095951,3096,P15822,CellAge,1,TRUE,Hivep1,70.1987,TRUE,Cells_EBV-transformed_lymphocytes,18.12,18.12,Low tissue specificity,Cell type enhanced,0,
HJURP,Holliday junction recognition protein,ENSG00000123485,55355,Q8NCD3,CellAge,1,TRUE,Hjurp,39.8396,FALSE,Cells_EBV-transformed_lymphocytes,46.88,46.88,Tissue enhanced,Cell type enhanced,32,CENPA(0.999)|NPM1(0.983)|RBBP4(0.975)|KIF2C(0.938)|KIF20A(0.935)
HK3,hexokinase 3,ENSG00000160883,3101,P52790,CellAge,1,TRUE,Hk3,85.3738,FALSE,Whole_Blood,310.54,310.54,Group enriched,Cell type enhanced,6,G6PD(0.939)|BAX(0.901)|ALDOA(0.858)|AKR1B1(0.83)|TLR8(0.762)
HMGA1,high mobility group AT-hook 1,ENSG00000137309,3159,P17096,CellAge|Reactome,2,TRUE,Hmga1,72.8972,TRUE,Cells_Cultured_fibroblasts,668.66,668.66,Tissue enhanced,Cell type enhanced,11,JUN(0.964)|HMGA2(0.902)|HMGCR(0.882)|IRF1(0.826)|PRMT6(0.797)
HMGA2,high mobility group AT-hook 2,ENSG00000149948,8091,P52926,CellAge|Reactome,2,TRUE,Hmga2,77.0642,TRUE,Cells_Cultured_fibroblasts,14.42,14.42,Tissue enhanced,Cell type enhanced,11,SMAD3(0.963)|SMAD2(0.941)|HMGA1(0.902)|TP53(0.867)|SMAD5(0.84)
HMGB1,high mobility group box 1,ENSG00000189403,3146,P09429,CellAge|GenAge|SenMayo,3,TRUE,Hmgb1,99.0698,TRUE,Uterus,136.13,136.13,Low tissue specificity,Cell type enhanced,26,BECN1(0.999)|TLR4(0.999)|TLR2(0.998)|TP53(0.997)|CXCL12(0.984)
HMGB2,high mobility group box 2,ENSG00000164104,3148,P26583,CellAge|GenAge,2,TRUE,Hmgb2,97.1292,TRUE,Cells_EBV-transformed_lymphocytes,543.18,543.18,Group enriched,Cell type enhanced,1,HMGB1(0.981)
HMGB3,high mobility group box 3,ENSG00000029993,3149,O15347,CellAge,1,FALSE,,,TRUE,Cells_EBV-transformed_lymphocytes,27.88,27.88,Tissue enhanced,Cell type enhanced,0,
HMGCR,3-hydroxy-3-methylglutaryl-CoA reductase,ENSG00000113161,3156,P04035,CellAge,1,TRUE,Hmgcr,93.4685,TRUE,Skin_Not_Sun_Exposed_Suprapubic,80.4,80.4,Tissue enhanced,Cell type enhanced,15,MVK(0.999)|FDPS(0.967)|SREBF1(0.956)|PRKAA2(0.932)|PMVK(0.913)
HNRNPA1,heterogeneous nuclear ribonucleoprotein A1,ENSG00000135486,3178,P09651,CellAge,1,TRUE,Hnrnpa1,86.0215,TRUE,Ovary,1092.5,1092.5,Low tissue specificity,Cell type enhanced,28,HNRNPC(0.999)|PTBP1(0.998)|SRSF1(0.993)|SRSF3(0.97)|ELAVL1(0.965)
HNRNPA3,heterogeneous nuclear ribonucleoprotein A3,ENSG00000170144,220988,P51991,CellAge,1,FALSE,,,TRUE,Ovary,235.9,235.9,Low tissue specificity,Low cell type specificity,15,HNRNPD(0.999)|HNRNPC(0.969)|PTBP1(0.965)|HNRNPA1(0.949)|SRSF1(0.918)
HNRNPAB,heterogeneous nuclear ribonucleoprotein A/B,ENSG00000197451,3182,Q99729,CellAge,1,TRUE,Hnrnpab,85.8434,TRUE,Cells_EBV-transformed_lymphocytes,266.41,266.41,Low tissue specificity,Cell type enhanced,12,HNRNPC(0.958)|PTBP1(0.951)|YBX1(0.898)|HNRNPA1(0.844)|SRSF1(0.824)
HNRNPC,heterogeneous nuclear ribonucleoprotein C,ENSG00000092199,3183,P07910,CellAge,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,281.33,281.33,Low tissue specificity,Cell type enhanced,33,HNRNPA1(0.999)|PTBP1(0.996)|DHX9(0.992)|ILF3(0.985)|SRSF3(0.981)
HNRNPD,heterogeneous nuclear ribonucleoprotein D,ENSG00000138668,3184,Q14103,CellAge,1,TRUE,Hnrnpd,96.9014,TRUE,Cells_EBV-transformed_lymphocytes,255.06,255.06,Low tissue specificity,Low cell type specificity,22,HNRNPA3(0.999)|HSPA8(0.98)|ELAVL1(0.97)|DNMT1(0.968)|HNRNPC(0.962)
HOPX,HOP homeobox,ENSG00000171476,84525,Q9BPY8,CellAge,1,TRUE,Hopx,73.6264,TRUE,Skin_Sun_Exposed_Lower_leg,821.21,821.21,Tissue enhanced,Cell type enriched,2,HDAC2(0.973)|SRF(0.755)
HOXA9,homeobox A9,ENSG00000078399,3205,P31269,CellAge,1,TRUE,Hoxa9,98.1618,TRUE,Uterus,35.2,35.2,Tissue enhanced,Cell type enhanced,2,MEN1(0.74)|DDB1(0.706)
HOXB7,homeobox B7,ENSG00000260027,3217,P09629,GenAge,1,TRUE,Hoxb7,94.0092,TRUE,Kidney_Medulla,36.92,36.92,Tissue enriched,Cell type enhanced,4,XRCC6(0.971)|PRKDC(0.954)|XRCC5(0.946)|HOXC4(0.871)
HOXC4,homeobox C4,ENSG00000198353,3221,P09017,GenAge,1,TRUE,Hoxc4,98.8636,TRUE,Fallopian_Tube,42.77,42.77,Tissue enhanced,Cell type enhanced,2,HOXB7(0.871)|XRCC6(0.723)
HRAS,"HRas proto-oncogene, GTPase",ENSG00000174775,3265,P01112,CellAge|GenAge,2,TRUE,Hras,100,TRUE,Skin_Not_Sun_Exposed_Suprapubic,107.71,107.71,Tissue enhanced,Cell type enhanced,62,BRAF(0.999)|RAF1(0.999)|RASSF5(0.999)|PIK3CA(0.995)|EGFR(0.994)
HS2ST1,heparan sulfate 2-O-sulfotransferase 1,ENSG00000153936,9653,Q7LGA3,CellAge,1,TRUE,Hs2st1,97.4719,TRUE,Cells_EBV-transformed_lymphocytes,30.77,30.77,Low tissue specificity,Cell type enhanced,2,NDST2(0.82)|SDC1(0.707)
HSF1,heat shock transcription factor 1,ENSG00000185122,3297,Q00613,CellAge|GenAge,2,TRUE,Hsf1,89.7921,FALSE,Testis,247.12,247.12,Low tissue specificity,Cell type enhanced,19,HSP90AA1(0.998)|HSP90AB1(0.992)|EEF1A1(0.955)|HSPA1B(0.944)|HSPA8(0.928)
HSP90AA1,heat shock protein 90 alpha family class A member 1,ENSG00000080824,3320,P07900,CellAge|GenAge,2,TRUE,Hsp90aa1,99.1803,TRUE,Testis,901.95,901.95,Low tissue specificity,Cell type enhanced,147,AKT1(0.999)|AR(0.999)|EGFR(0.999)|ERBB2(0.999)|ESR1(0.999)
HSP90AB1,heat shock protein 90 alpha family class B member 1,ENSG00000096384,3326,P08238,CellAge,1,TRUE,Hsp90ab1,99.5856,TRUE,Ovary,1822.77,1822.77,Low tissue specificity,Cell type enhanced,118,AKT1(0.999)|AR(0.999)|CDK4(0.999)|HSPA8(0.999)|STUB1(0.999)
HSPA1A,heat shock protein family A (Hsp70) member 1A,ENSG00000234475,3303,P0DMV9,CellAge|GenAge,2,FALSE,,,FALSE,,,,,,14,HSPA1B(0.994)|YBX1(0.985)|HSP90AA1(0.98)|HSPB1(0.977)|HSP90AB1(0.969)
HSPA1B,heat shock protein family A (Hsp70) member 1B,ENSG00000204388,3304,P0DMV9,GenAge,1,TRUE,Hspa1b,95.3198,FALSE,Kidney_Medulla,119.32,119.32,Low tissue specificity,Group enriched,28,HSP90AA1(0.998)|TLR2(0.998)|HSPA1A(0.994)|HSP90AB1(0.991)|YBX1(0.991)
HSPA2,heat shock protein family A (Hsp70) member 2,ENSG00000126803,3306,P54652,CellAge,1,TRUE,Hspa2,98.2786,TRUE,Brain_Spinal_cord_cervical_c-1,206,206,Tissue enhanced,Cell type enhanced,13,TLR2(0.909)|MAPK8(0.906)|MAPK9(0.905)|STUB1(0.901)|HSP90AB1(0.899)
HSPA5,heat shock protein family A (Hsp70) member 5,ENSG00000044574,3309,P11021,CellAge,1,TRUE,Hspa5,98.6239,TRUE,Cells_Cultured_fibroblasts,746.63,746.63,Low tissue specificity,Cell type enhanced,44,ATF6(0.999)|EIF2AK3(0.999)|HYOU1(0.999)|CALR(0.995)|HSPA8(0.983)
HSPA8,heat shock protein family A (Hsp70) member 8,ENSG00000109971,3312,P11142,GenAge,1,FALSE,,,TRUE,Cells_EBV-transformed_lymphocytes,989.89,989.89,Low tissue specificity,Cell type enhanced,61,BAG3(0.999)|HSP90AA1(0.999)|HSP90AB1(0.999)|STUB1(0.999)|HSPB1(0.988)
HSPA9,heat shock protein family A (Hsp70) member 9,ENSG00000113013,3313,P38646,CellAge|GenAge,2,TRUE,Hspa9,98.38,TRUE,Cells_EBV-transformed_lymphocytes,301.84,301.84,Low tissue specificity,Cell type enhanced,33,HSPD1(0.999)|TP53(0.998)|ITPR3(0.996)|ITPR1(0.995)|PARK7(0.992)
HSPB1,heat shock protein family B (small) member 1,ENSG00000106211,3315,P04792,CellAge,1,TRUE,Hspb1,84.3902,TRUE,Esophagus_Mucosa,4133.86,4133.86,Tissue enhanced,Cell type enhanced,31,MAPKAPK2(0.999)|MAPKAPK5(0.995)|AKT1(0.991)|HSPA8(0.988)|BAG3(0.98)
HSPD1,heat shock protein family D (Hsp60) member 1,ENSG00000144381,3329,P10809,GenAge,1,TRUE,Hspd1,97.5567,TRUE,Cells_EBV-transformed_lymphocytes,621.52,621.52,Tissue enhanced,Cell type enhanced,19,HSPA9(0.999)|TLR4(0.999)|TLR2(0.976)|HSP90AB1(0.97)|HSP90AA1(0.963)
HTRA1,HtrA serine peptidase 1,ENSG00000166033,5654,Q92743,CellAge,1,TRUE,Htra1,91.875,TRUE,Artery_Aorta,810.74,810.74,Tissue enhanced,Cell type enhanced,3,XIAP(0.805)|MAPT(0.754)|CLPP(0.742)
HTRA2,HtrA serine peptidase 2,ENSG00000115317,27429,O43464,GenAge,1,TRUE,Htra2,84.9345,TRUE,Cells_EBV-transformed_lymphocytes,62.26,62.26,Low tissue specificity,Cell type enhanced,12,XIAP(0.999)|TNFRSF1A(0.996)|PINK1(0.994)|PRKN(0.871)|PSEN1(0.849)
HTT,huntingtin,ENSG00000197386,3064,P42858,GenAge,1,TRUE,Htt,90.2292,TRUE,Cells_EBV-transformed_lymphocytes,62.93,62.93,Low tissue specificity,Cell type enhanced,37,TP53(0.998)|CREBBP(0.997)|ITPR1(0.995)|GAPDH(0.993)|CREB1(0.982)
HYOU1,hypoxia up-regulated 1,ENSG00000149428,10525,Q9Y4L1,CellAge,1,TRUE,Hyou1,92.0921,TRUE,Testis,132.36,132.36,Low tissue specificity,Cell type enhanced,8,HSPA5(0.999)|CALR(0.947)|PPIB(0.93)|HSP90AB1(0.848)|HSP90AA1(0.842)
ICAM1,intercellular adhesion molecule 1,ENSG00000090339,3383,P05362,SenMayo,1,TRUE,Icam1,53.1955,FALSE,Lung,217.44,217.44,Tissue enhanced,Cell type enhanced,61,MSN(0.991)|SELPLG(0.991)|CD28(0.977)|ICAM3(0.964)|PLCG2(0.952)
ICAM3,intercellular adhesion molecule 3,ENSG00000076662,3385,P32942,SenMayo,1,FALSE,,,TRUE,Whole_Blood,214.43,214.43,Tissue enhanced,Cell type enhanced,3,ICAM1(0.964)|MSN(0.829)|ERVW-1(0.756)
ID1,inhibitor of DNA binding 1,ENSG00000125968,3397,P41134,CellAge|Reactome,2,TRUE,Id1,90.3226,TRUE,Thyroid,409.56,409.56,Low tissue specificity,Cell type enhanced,4,FOXO3(0.989)|TCF3(0.973)|ETS2(0.958)|ETS1(0.783)
IFI16,interferon gamma inducible protein 16,ENSG00000163565,3428,Q16666,CellAge,1,TRUE,Ifi204,32.4841,FALSE,Cells_EBV-transformed_lymphocytes,235.21,235.21,Low tissue specificity,Cell type enhanced,9,TP53(0.988)|BRCA1(0.953)|TBK1(0.892)|IRF3(0.836)|IRF7(0.802)
IFNB1,interferon beta 1,ENSG00000171855,3456,P01574,GenAge|Reactome,2,TRUE,Ifnb1,48.1283,TRUE,Cells_EBV-transformed_lymphocytes,0.11,0.11,Not detected,Cell type enriched,44,TLR4(0.998)|TLR3(0.995)|IRF3(0.985)|IRF7(0.978)|TBK1(0.972)
IFNG,interferon gamma,ENSG00000111537,3458,P01579,CellAge,1,TRUE,Ifng,36.747,TRUE,Whole_Blood,1.08,1.08,Group enriched,Group enriched,88,IL1B(0.998)|JAK2(0.998)|IL10(0.995)|TNF(0.991)|IL2(0.99)
IGF1,insulin like growth factor 1,ENSG00000017427,3479,P05019,GenAge|SenMayo,2,TRUE,Igf1,91.5033,TRUE,Cervix_Endocervix,46.66,46.66,Low tissue specificity,Cell type enhanced,81,IGF1R(0.999)|IGFBP1(0.999)|IGFBP2(0.999)|IGFBP3(0.999)|IGFBP4(0.999)
IGF1R,insulin like growth factor 1 receptor,ENSG00000140443,3480,P08069,GenAge,1,TRUE,Igf1r,96.1229,TRUE,Artery_Tibial,41.21,41.21,Low tissue specificity,Cell type enhanced,77,ESR1(0.999)|IGF1(0.999)|IGF2(0.999)|INS(0.999)|IRS1(0.999)
IGF2,insulin like growth factor 2,ENSG00000167244,3481,P01344,GenAge,1,TRUE,Igf2,83.8889,TRUE,Adipose_Visceral_Omentum,103.17,103.17,Tissue enriched,Cell type enhanced,39,IGF1R(0.999)|IGFBP1(0.999)|IGFBP2(0.999)|IGFBP3(0.999)|IGFBP6(0.999)
IGFBP1,insulin like growth factor binding protein 1,ENSG00000146678,3484,P08833,CellAge|SenMayo,2,TRUE,Igfbp1,68.3398,TRUE,Liver,380.05,380.05,Tissue enriched,Group enriched,8,IGF1(0.999)|IGF2(0.999)|INS(0.994)|IGFBP4(0.972)|IGFBP6(0.956)
IGFBP2,insulin like growth factor binding protein 2,ENSG00000115457,3485,P18065,GenAge|SenMayo,2,TRUE,Igfbp2,81.5385,TRUE,Artery_Aorta,1329.05,1329.05,Tissue enhanced,Cell type enhanced,7,IGF1(0.999)|IGF2(0.999)|INS(0.982)|NIPA2(0.915)|IGFBP3(0.836)
IGFBP3,insulin like growth factor binding protein 3,ENSG00000146674,3486,P17936,CellAge|GenAge|SenMayo,3,TRUE,Igfbp3,81.7869,TRUE,Adipose_Visceral_Omentum,325.53,325.53,Tissue enhanced,Cell type enriched,21,IGF1(0.999)|IGF2(0.999)|INS(0.995)|EGFR(0.981)|IGFBP5(0.978)
IGFBP4,insulin like growth factor binding protein 4,ENSG00000141753,3487,P22692,SenMayo,1,TRUE,Igfbp4,90.6977,FALSE,Ovary,2504.96,2504.96,Low tissue specificity,Cell type enhanced,4,IGF1(0.999)|IGF2(0.993)|PAPPA(0.976)|IGFBP1(0.972)
IGFBP5,insulin like growth factor binding protein 5,ENSG00000115461,3488,P24593,CellAge|SenMayo,2,TRUE,Igfbp5,95.2206,TRUE,Ovary,2842.51,2842.51,Tissue enhanced,Cell type enhanced,8,IGF1(0.999)|IGF2(0.998)|IGFBP3(0.978)|PAPPA(0.977)|IGF1R(0.802)
IGFBP6,insulin like growth factor binding protein 6,ENSG00000167779,3489,P24592,SenMayo,1,TRUE,Igfbp6,67.5,TRUE,Nerve_Tibial,1529.81,1529.81,Tissue enhanced,Cell type enhanced,8,IGF1(0.999)|IGF2(0.999)|IGFBP1(0.956)|IGFBP3(0.777)|INS(0.756)
IGFBP7,insulin like growth factor binding protein 7,ENSG00000163453,3490,Q16270,CellAge|Reactome|SenMayo,3,TRUE,Igfbp7,91.1348,TRUE,Artery_Aorta,5638.87,5638.87,Tissue enhanced,Cell type enhanced,12,IGF1(0.995)|INS(0.992)|IGF2(0.99)|CCN2(0.921)|TIMP2(0.874)
IKBKB,inhibitor of nuclear factor kappa B kinase subunit beta,ENSG00000104365,3551,O14920,GenAge,1,TRUE,Ikbkb,92.5926,TRUE,Spleen,67.25,67.25,Low tissue specificity,Low cell type specificity,55,CHUK(0.999)|IKBKG(0.999)|NFKB1(0.999)|NFKBIA(0.999)|RELA(0.999)
IKBKG,inhibitor of nuclear factor kappa B kinase regulatory subunit gamma,ENSG00000269335,8517,Q9Y6K9,CellAge,1,TRUE,Ikbkg,86.6348,TRUE,Cells_Cultured_fibroblasts,7.44,7.44,Low tissue specificity,Cell type enhanced,46,CHUK(0.999)|IKBKB(0.999)|IRAK4(0.999)|MAP3K7(0.999)|MYD88(0.999)
IL10,interleukin 10,ENSG00000136634,3586,P22301,SenMayo,1,TRUE,Il10,73.0337,TRUE,Cells_EBV-transformed_lymphocytes,8.85,8.85,Tissue enhanced,Cell type enhanced,92,IL6(0.997)|IFNG(0.995)|TNF(0.992)|IL1B(0.991)|IL7(0.988)
IL13,interleukin 13,ENSG00000169194,3596,P35225,SenMayo,1,TRUE,Il13,52.0548,FALSE,Testis,64.56,64.56,Tissue enriched,Cell type enhanced,46,STAT6(0.971)|IFNG(0.961)|IL6(0.957)|TNF(0.957)|IL1B(0.953)
IL15,interleukin 15,ENSG00000164136,3600,P40933,SenMayo,1,TRUE,Il15,72.8395,TRUE,Thyroid,11.83,11.83,Low tissue specificity,Cell type enhanced,35,IL2RG(0.999)|IL7R(0.985)|IL7(0.968)|IL2(0.958)|IFNG(0.939)
IL18,interleukin 18,ENSG00000150782,3606,Q14116,SenMayo,1,TRUE,Il18,64.2487,FALSE,Skin_Sun_Exposed_Lower_leg,169.06,169.06,Tissue enhanced,Cell type enhanced,37,IL1A(0.997)|IL1B(0.99)|NFKB1(0.979)|IL6(0.97)|IL1R1(0.965)
IL1A,interleukin 1 alpha,ENSG00000115008,3552,P01583,CellAge|Reactome|SenMayo,3,TRUE,Il1a,60.1476,FALSE,Testis,18.27,18.27,Tissue enhanced,Cell type enhanced,63,IL1B(0.999)|IL1R1(0.999)|CSF2(0.997)|IL18(0.997)|IL2(0.997)
IL1B,interleukin 1 beta,ENSG00000125538,3553,P01584,SenMayo,1,TRUE,Il1b,67.658,TRUE,Whole_Blood,24.53,24.53,Tissue enhanced,Cell type enhanced,122,IL1A(0.999)|IL1R1(0.999)|IL2(0.999)|MYD88(0.999)|CSF2(0.998)
IL1R1,interleukin 1 receptor type 1,ENSG00000115594,3554,P14778,CellAge,1,TRUE,Il1r1,68.717,TRUE,Cells_Cultured_fibroblasts,188.51,188.51,Low tissue specificity,Cell type enriched,28,IL1A(0.999)|IL1B(0.999)|IL1RN(0.999)|MYD88(0.999)|IL6(0.997)
IL1RN,interleukin 1 receptor antagonist,ENSG00000136689,3557,P18510,CellAge,1,TRUE,Il1rn,67.7966,TRUE,Esophagus_Mucosa,1638.91,1638.91,Tissue enriched,Cell type enriched,15,IL1R1(0.999)|IL1A(0.99)|IL1B(0.968)|CXCL8(0.926)|IL6(0.925)
IL2,interleukin 2,ENSG00000109471,3558,P60568,GenAge|SenMayo,2,TRUE,Il2,63.3987,FALSE,Small_Intestine_Terminal_Ileum,0.62,0.62,Not detected,Group enriched,61,IL1B(0.999)|IL2RG(0.999)|IL6(0.999)|CSF2(0.997)|IL1A(0.997)
IL24,interleukin 24,ENSG00000162892,11009,Q13007,CellAge,1,TRUE,Il24,58.7379,FALSE,Spleen,41.85,41.85,Tissue enhanced,Group enriched,5,IL10(0.856)|STAT3(0.831)|IL7R(0.74)|EGFR(0.736)|IL2RG(0.71)
IL2RG,interleukin 2 receptor subunit gamma,ENSG00000147168,3561,P31785,GenAge,1,TRUE,Il2rg,70.7317,TRUE,Whole_Blood,410.67,410.67,Tissue enhanced,Cell type enhanced,22,IL15(0.999)|IL2(0.999)|IL7(0.999)|IL7R(0.999)|STAT5A(0.977)
IL32,interleukin 32,ENSG00000008517,9235,P24001,SenMayo,1,FALSE,,,FALSE,Spleen,139.56,139.56,Tissue enhanced,Cell type enhanced,8,ITGB3(0.962)|MET(0.921)|PRKCD(0.896)|CCL5(0.736)|CXCL8(0.733)
IL6,interleukin 6,ENSG00000136244,3569,P05231,CellAge|GenAge|Reactome|SenMayo,4,TRUE,Il6,41.0377,FALSE,Adipose_Visceral_Omentum,54.44,54.44,Tissue enhanced,Cell type enhanced,156,IL2(0.999)|IL6ST(0.999)|IL10(0.997)|IL1R1(0.997)|TNFRSF1A(0.997)
IL6ST,interleukin 6 cytokine family signal transducer,ENSG00000134352,3572,P40189,SenMayo,1,TRUE,Il6st,77.1242,FALSE,Cells_Cultured_fibroblasts,214.04,214.04,Low tissue specificity,Cell type enhanced,23,IL6(0.999)|JAK2(0.993)|STAT3(0.992)|PTPN11(0.981)|CTF1(0.98)
IL7,interleukin 7,ENSG00000104432,3574,P13232,GenAge|SenMayo,2,TRUE,Il7,60.452,FALSE,Cells_EBV-transformed_lymphocytes,9.38,9.38,Low tissue specificity,Cell type enhanced,39,IL2RG(0.999)|IL7R(0.999)|IL2(0.997)|HGF(0.991)|IL10(0.988)
IL7R,interleukin 7 receptor,ENSG00000168685,3575,P16871,GenAge,1,TRUE,Il7r,64.488,FALSE,Lung,89.71,89.71,Tissue enhanced,Group enriched,26,IL2RG(0.999)|IL7(0.999)|IL15(0.985)|IL2(0.978)|STAT5B(0.941)
ILF3,interleukin enhancer binding factor 3,ENSG00000129351,3609,Q12906,CellAge,1,TRUE,Ilf3,92.9844,TRUE,Ovary,133.83,133.83,Low tissue specificity,Low cell type specificity,18,HNRNPC(0.985)|DHX9(0.981)|EIF2AK2(0.977)|HNRNPA1(0.96)|ELAVL1(0.915)
ILK,integrin linked kinase,ENSG00000166333,3611,Q13418,CellAge,1,TRUE,Ilk,99.5575,TRUE,Colon_Sigmoid,478.97,478.97,Low tissue specificity,Cell type enhanced,19,AKT1(0.998)|FERMT2(0.997)|RICTOR(0.977)|AKT3(0.942)|PIK3R1(0.937)
IMMT,inner membrane mitochondrial protein,ENSG00000132305,10989,Q16891,CellAge,1,TRUE,Immt,84.3008,TRUE,Cells_EBV-transformed_lymphocytes,119.52,119.52,Tissue enhanced,Cell type enhanced,9,HSPA9(0.881)|PIK3R5(0.853)|ERCC2(0.851)|PIK3CB(0.846)|ERCC3(0.845)
INCENP,inner centromere protein,ENSG00000149503,3619,Q9NQS7,CellAge,1,TRUE,Incenp,67.3203,TRUE,Cells_EBV-transformed_lymphocytes,45.11,45.11,Tissue enhanced,Cell type enhanced,24,AURKB(0.999)|BIRC5(0.999)|KIF20A(0.995)|AURKA(0.994)|PLK1(0.978)
ING1,inhibitor of growth family member 1,ENSG00000153487,3621,Q9UK53,CellAge,1,TRUE,Ing1,81.362,TRUE,Testis,18.06,18.06,Low tissue specificity,Cell type enhanced,16,HDAC1(0.997)|SIN3A(0.995)|RBBP4(0.987)|HDAC2(0.985)|H3-4(0.981)
ING2,inhibitor of growth family member 2,ENSG00000168556,3622,Q9H160,CellAge,1,TRUE,Ing2,96.7857,TRUE,Testis,62.58,62.58,Low tissue specificity,Cell type enhanced,17,SIN3A(0.999)|H3-4(0.994)|HDAC1(0.99)|HDAC2(0.988)|MORF4L1(0.972)
ING5,inhibitor of growth family member 5,ENSG00000168395,84289,Q8WYH8,CellAge,1,TRUE,Ing5,94.5833,TRUE,Ovary,30.76,30.76,Low tissue specificity,Low cell type specificity,4,TP53(0.969)|EP300(0.934)|ING1(0.896)|KAT5(0.865)
INHA,inhibin subunit alpha,ENSG00000123999,3623,P05111,SenMayo,1,TRUE,Inha,78.9617,TRUE,Testis,174.71,174.71,Group enriched,Cell type enhanced,0,
INPP4B,inositol polyphosphate-4-phosphatase type II B,ENSG00000109452,8821,O15327,CellAge,1,TRUE,Inpp4b,90.5844,TRUE,Fallopian_Tube,9.79,9.79,Low tissue specificity,Cell type enhanced,4,PTEN(0.967)|PIK3R1(0.949)|PIK3C2A(0.932)|ITPK1(0.9)
INS,insulin,ENSG00000254647,3630,P01308,GenAge,1,TRUE,Ins2,81.8182,TRUE,Pancreas,2325.26,2325.26,Tissue enriched,Cell type enriched,106,IGF1(0.999)|IGF1R(0.999)|INSR(0.999)|IRS1(0.999)|IRS2(0.998)
INSR,insulin receptor,ENSG00000171105,3643,P06213,GenAge,1,TRUE,Insr,94.5007,TRUE,Spleen,90.88,90.88,Low tissue specificity,Cell type enhanced,34,IGF1(0.999)|INS(0.999)|IRS1(0.999)|IRS2(0.999)|PTPN1(0.999)
IQGAP2,IQ motif containing GTPase activating protein 2,ENSG00000145703,10788,Q13576,SenMayo,1,TRUE,Iqgap2,88.9524,TRUE,Testis,42.42,42.42,Tissue enhanced,Cell type enhanced,1,CDC42(0.999)
IRAK4,interleukin 1 receptor associated kinase 4,ENSG00000198001,51135,Q9NWZ3,CellAge,1,TRUE,Irak4,83.2609,TRUE,Spleen,29.69,29.69,Low tissue specificity,Cell type enhanced,23,IKBKG(0.999)|MYD88(0.999)|TLR4(0.999)|IL1R1(0.996)|IRF7(0.996)
IRF1,interferon regulatory factor 1,ENSG00000125347,3659,P10914,CellAge,1,TRUE,Irf1,85.5385,TRUE,Whole_Blood,91.59,91.59,Tissue enhanced,Cell type enhanced,31,STAT1(0.999)|HDAC1(0.985)|EP300(0.984)|SPI1(0.974)|MDM2(0.97)
IRF3,interferon regulatory factor 3,ENSG00000126456,3661,Q14653,CellAge,1,TRUE,Irf3,70.2576,TRUE,Spleen,137.39,137.39,Low tissue specificity,Low cell type specificity,44,CREBBP(0.999)|EP300(0.999)|IRF7(0.999)|TBK1(0.999)|JUN(0.998)
IRF5,interferon regulatory factor 5,ENSG00000128604,3663,Q13568,CellAge,1,TRUE,Irf5,85.4086,TRUE,Cells_EBV-transformed_lymphocytes,112.79,112.79,Low tissue specificity,Cell type enhanced,10,MYD88(0.995)|CCL4(0.934)|STAT1(0.892)|TYK2(0.834)|IL10(0.775)
IRF7,interferon regulatory factor 7,ENSG00000185507,3665,Q92985,CellAge,1,TRUE,Irf7,62.8231,TRUE,Cells_EBV-transformed_lymphocytes,200.61,200.61,Tissue enhanced,Cell type enriched,33,IRF3(0.999)|MYD88(0.999)|IRAK4(0.996)|CHUK(0.993)|TBK1(0.992)
IRS1,insulin receptor substrate 1,ENSG00000169047,3667,P35568,GenAge,1,TRUE,Irs1,89.0499,TRUE,Cells_Cultured_fibroblasts,50.34,50.34,Low tissue specificity,Cell type enhanced,66,GRB2(0.999)|IGF1R(0.999)|INS(0.999)|INSR(0.999)|PIK3CA(0.999)
IRS2,insulin receptor substrate 2,ENSG00000185950,8660,Q9Y4H2,GenAge,1,TRUE,Irs2,85.5007,TRUE,Cells_Cultured_fibroblasts,54.93,54.93,Tissue enhanced,Cell type enhanced,38,GRB2(0.999)|INSR(0.999)|IGF1R(0.998)|INS(0.998)|PIK3R1(0.998)
ITGA2,integrin subunit alpha 2,ENSG00000164171,3673,P17301,SenMayo,1,TRUE,Itga2,82.3031,TRUE,Lung,22.31,22.31,Low tissue specificity,Cell type enhanced,12,ITGB3(0.984)|PTK2(0.94)|ITGB4(0.924)|PIK3CB(0.918)|PIK3R1(0.916)
ITGB3,integrin subunit beta 3,ENSG00000259207,3690,P05106,CellAge,1,TRUE,Itgb3,90.6091,TRUE,Artery_Aorta,59.1,59.1,Tissue enhanced,Cell type enriched,29,SRC(0.998)|SPP1(0.994)|PTK2(0.99)|ITGA2(0.984)|KDR(0.979)
ITGB4,integrin subunit beta 4,ENSG00000132470,3691,P16144,CellAge,1,TRUE,Itgb4,85.4007,FALSE,Nerve_Tibial,362.25,362.25,Tissue enhanced,Cell type enhanced,12,PTK2(0.964)|SRC(0.948)|ERBB2(0.944)|ITGA2(0.924)|SDC1(0.843)
ITPK1,inositol-tetrakisphosphate 1-kinase,ENSG00000100605,3705,Q13572,CellAge,1,TRUE,Itpk1,93.9613,TRUE,Brain_Frontal_Cortex_BA9,110.4,110.4,Tissue enhanced,Cell type enhanced,3,ITPKA(0.938)|ITPKB(0.927)|INPP4B(0.9)
ITPKA,inositol-trisphosphate 3-kinase A,ENSG00000137825,3706,P23677,SenMayo,1,TRUE,Itpka,93.2755,TRUE,Brain_Cortex,75.67,75.67,Tissue enhanced,Cell type enriched,3,ITPK1(0.938)|ITPKB(0.936)|PLCG2(0.728)
ITPKB,inositol-trisphosphate 3-kinase B,ENSG00000143772,3707,P27987,CellAge,1,TRUE,Itpkb,77.4841,TRUE,Uterus,94.22,94.22,Tissue enhanced,Cell type enhanced,3,ITPKA(0.936)|ITPK1(0.927)|PLCG2(0.755)
ITPR1,"inositol 1,4,5-trisphosphate receptor type 1",ENSG00000150995,3708,Q14643,CellAge,1,TRUE,Itpr1,98.2959,TRUE,Artery_Tibial,82.02,82.02,Low tissue specificity,Cell type enhanced,22,BECN1(0.998)|BCL2(0.996)|HSPA9(0.995)|HTT(0.995)|AKT1(0.981)
ITPR2,"inositol 1,4,5-trisphosphate receptor type 2",ENSG00000123104,3709,Q14571,CellAge,1,TRUE,Itpr2,95.8164,TRUE,Cells_EBV-transformed_lymphocytes,29.77,29.77,Tissue enhanced,Cell type enhanced,8,PLCG2(0.958)|ITPR3(0.953)|ITPR1(0.943)|PSEN1(0.92)|PRKCA(0.919)
ITPR3,"inositol 1,4,5-trisphosphate receptor type 3",ENSG00000096433,3710,Q14573,CellAge,1,TRUE,Itpr3,95.0206,TRUE,Nerve_Tibial,135.75,135.75,Low tissue specificity,Cell type enhanced,20,HSPA9(0.996)|BCL2(0.993)|BECN1(0.987)|AKT1(0.967)|ITPR1(0.965)
ITSN2,intersectin 2,ENSG00000198399,50618,Q9NZM3,CellAge,1,TRUE,Itsn2,90.8073,TRUE,Thyroid,44.79,44.79,Low tissue specificity,Cell type enhanced,4,CDC42(0.979)|BIN1(0.866)|RHOA(0.713)|EGFR(0.7)
JAK2,Janus kinase 2,ENSG00000096968,3717,O60674,CellAge|GenAge,2,TRUE,Jak2,93.7279,TRUE,Artery_Tibial,68.89,68.89,Low tissue specificity,Cell type enhanced,81,EPOR(0.999)|GHR(0.999)|LEPR(0.999)|SOCS1(0.999)|STAT1(0.999)
JPT1,Jupiter microtubule associated homolog 1,ENSG00000189159,51155,Q9UK76,CellAge,1,TRUE,Jpt1,90.2597,FALSE,Testis,175.6,175.6,Tissue enhanced,Cell type enhanced,0,
JUN,"Jun proto-oncogene, AP-1 transcription factor subunit",ENSG00000177606,3725,P05412,CellAge|GenAge|Reactome|SenMayo,4,TRUE,Jun,96.3746,TRUE,Adipose_Visceral_Omentum,528.97,528.97,Low tissue specificity,Cell type enhanced,155,ATF2(0.999)|ATF3(0.999)|EP300(0.999)|ESR1(0.999)|FOS(0.999)
JUNB,"JunB proto-oncogene, AP-1 transcription factor subunit",ENSG00000171223,3726,P17275,CellAge,1,TRUE,Junb,93.0836,TRUE,Artery_Tibial,1697.92,1697.92,Tissue enhanced,Cell type enhanced,20,FOS(0.999)|JUN(0.999)|JUND(0.999)|MAPK9(0.979)|MAPK8(0.973)
JUND,"JunD proto-oncogene, AP-1 transcription factor subunit",ENSG00000130522,3727,P17535,GenAge,1,TRUE,Jund,77.5216,TRUE,Ovary,761.45,761.45,Low tissue specificity,Cell type enhanced,22,FOS(0.999)|JUN(0.999)|JUNB(0.999)|MEN1(0.998)|MAPK8(0.995)
KAT5,lysine acetyltransferase 5,ENSG00000172977,10524,Q92993,CellAge|Reactome,2,TRUE,Kat5,93.0403,FALSE,Uterus,62.51,62.51,Low tissue specificity,Cell type enhanced,64,EP400(0.999)|MORF4L1(0.999)|RUVBL2(0.999)|TRRAP(0.999)|YEATS4(0.999)
KCNA1,potassium voltage-gated channel subfamily A member 1,ENSG00000111262,3736,Q09470,CellAge,1,TRUE,Kcna1,98.3838,TRUE,Brain_Cerebellar_Hemisphere,56.04,56.04,Tissue enriched,Cell type enhanced,2,KCNA3(0.966)|CACNA1A(0.892)
KCNA3,potassium voltage-gated channel subfamily A member 3,ENSG00000177272,3738,P22001,GenAge,1,TRUE,Kcna3,88.6957,FALSE,Cells_EBV-transformed_lymphocytes,7.97,7.97,Tissue enhanced,Cell type enhanced,2,KCNA1(0.966)|CAV1(0.829)
KCNJ12,potassium inwardly rectifying channel subfamily J member 12,ENSG00000184185,3768,Q14500,CellAge,1,TRUE,Kcnj12,96.0739,TRUE,Brain_Cerebellar_Hemisphere,82.37,82.37,Group enriched,Cell type enhanced,0,
KDM1A,lysine demethylase 1A,ENSG00000004487,23028,O60341,CellAge,1,TRUE,Kdm1a,95.5479,TRUE,Testis,194.02,194.02,Low tissue specificity,Low cell type specificity,70,HDAC1(0.999)|HDAC2(0.999)|DNMT1(0.998)|SNAI1(0.998)|EZH2(0.997)
KDM2B,lysine demethylase 2B,ENSG00000089094,84678,Q8NHM5,CellAge,1,TRUE,Kdm2b,92.0659,TRUE,Cells_EBV-transformed_lymphocytes,35.19,35.19,Low tissue specificity,Cell type enhanced,14,RNF2(0.999)|RING1(0.996)|CBX8(0.863)|EZH2(0.863)|CBX7(0.841)
KDM4A,lysine demethylase 4A,ENSG00000066135,9682,O75164,CellAge,1,TRUE,Kdm4a,93.609,FALSE,Cells_Cultured_fibroblasts,27.21,27.21,Low tissue specificity,Cell type enhanced,18,H3-4(0.998)|H3C1(0.975)|KDM1A(0.966)|H1-4(0.952)|NCOR1(0.93)
KDM4C,lysine demethylase 4C,ENSG00000107077,23081,Q9H3R0,CellAge,1,TRUE,Kdm4c,84.4697,TRUE,Brain_Cerebellar_Hemisphere,34.11,34.11,Low tissue specificity,Low cell type specificity,5,HIF1A(0.953)|KDM1A(0.924)|AR(0.823)|SUV39H1(0.773)|EHMT2(0.717)
KDM5B,lysine demethylase 5B,ENSG00000117139,10765,Q9UGL1,CellAge,1,TRUE,Kdm5b,94.2357,TRUE,Testis,105.67,105.67,Tissue enhanced,Cell type enhanced,10,KDM1A(0.988)|HDAC1(0.986)|MYC(0.966)|EZH2(0.845)|AR(0.788)
KDM6B,lysine demethylase 6B,ENSG00000132510,23135,O15054,CellAge|Reactome,2,TRUE,Kdm6b,92.2702,TRUE,Whole_Blood,64.36,64.36,Low tissue specificity,Cell type enhanced,32,EZH2(0.942)|SMARCA4(0.935)|H3-4(0.928)|SUZ12(0.899)|EED(0.858)
KDR,kinase insert domain receptor,ENSG00000128052,3791,P35968,CellAge,1,TRUE,Kdr,85.9145,TRUE,Thyroid,80.12,80.12,Low tissue specificity,Group enriched,61,PECAM1(0.999)|PGF(0.999)|VEGFC(0.999)|FGF2(0.998)|SRC(0.998)
KEAP1,kelch like ECH associated protein 1,ENSG00000079999,9817,Q14145,CellAge,1,TRUE,Keap1,94.0705,TRUE,Muscle_Skeletal,88.33,88.33,Tissue enhanced,Low cell type specificity,29,NFE2L2(0.999)|RBX1(0.999)|SQSTM1(0.999)|IKBKB(0.997)|RELA(0.956)
KIF11,kinesin family member 11,ENSG00000138160,3832,P52732,CellAge,1,TRUE,Kif11,79.7348,TRUE,Cells_EBV-transformed_lymphocytes,53.23,53.23,Tissue enhanced,Cell type enhanced,46,BUB1B(0.994)|CDK1(0.987)|BUB1(0.985)|TTK(0.984)|KIF20A(0.98)
KIF20A,kinesin family member 20A,ENSG00000112984,10112,O95235,CellAge,1,TRUE,Kif20a,86.8539,TRUE,Cells_EBV-transformed_lymphocytes,39.53,39.53,Tissue enhanced,Cell type enhanced,36,RACGAP1(0.997)|INCENP(0.995)|AURKB(0.99)|PLK1(0.99)|KIF11(0.98)
KIF2C,kinesin family member 2C,ENSG00000142945,11004,Q99661,CellAge,1,TRUE,Kif2c,83.0345,FALSE,Testis,159.47,159.47,Group enriched,Cell type enriched,37,TPX2(0.999)|AURKB(0.996)|BUB1(0.994)|PLK1(0.994)|BUB1B(0.991)
KIFC1,kinesin family member C1,ENSG00000233450,3833,Q9BW19,CellAge,1,FALSE,,,FALSE,,,,,,29,KIF11(0.963)|KIF20A(0.941)|KIF2C(0.932)|BUB1(0.916)|AURKB(0.906)
KITLG,KIT ligand,ENSG00000049130,4254,P21583,SenMayo,1,TRUE,Kitl,82.7839,TRUE,Cells_Cultured_fibroblasts,65.55,65.55,Low tissue specificity,Cell type enhanced,35,PDGFRA(0.981)|PDGFRB(0.951)|EGFR(0.95)|CD34(0.934)|KDR(0.934)
KL,klotho,ENSG00000133116,9365,Q9UEF7,CellAge|GenAge,2,TRUE,Kl,85.3755,TRUE,Kidney_Cortex,18.73,18.73,Group enriched,Cell type enhanced,12,FGF23(0.999)|FGFR1(0.999)|FGF7(0.99)|FGF21(0.978)|FGFR3(0.966)
KLF4,KLF transcription factor 4,ENSG00000136826,9314,O43474,CellAge,1,TRUE,Klf4,91.4405,TRUE,Skin_Not_Sun_Exposed_Suprapubic,626.92,626.92,Tissue enhanced,Cell type enhanced,31,SOX2(0.998)|NANOG(0.994)|POU5F1(0.994)|CTNNB1(0.991)|HDAC2(0.949)
KNDC1,kinase non-catalytic C-lobe domain containing 1,ENSG00000171798,85442,Q76NI1,CellAge,1,TRUE,Kndc1,76.8439,TRUE,Brain_Cerebellum,87.79,87.79,Tissue enhanced,Cell type enhanced,0,
KRT19,keratin 19,ENSG00000171345,3880,P08727,CellAge,1,TRUE,Krt19,82.75,TRUE,Minor_Salivary_Gland,1120.27,1120.27,Tissue enhanced,Cell type enhanced,4,GPC3(0.785)|PECAM1(0.781)|CDH1(0.747)|LGALS3(0.747)
KSR2,kinase suppressor of ras 2,ENSG00000171435,283455,Q6VAB6,CellAge,1,TRUE,Ksr2,96.5263,TRUE,Pituitary,16.8,16.8,Tissue enhanced,Cell type enhanced,4,MAP2K1(0.997)|BRAF(0.823)|MAP2K2(0.811)|MAPK3(0.709)
LAMP2,lysosome associated membrane protein 2,ENSG00000005893,3920,P13473,CellAge,1,TRUE,Lamp2,65.3659,TRUE,Brain_Spinal_cord_cervical_c-1,148.05,148.05,Low tissue specificity,Cell type enhanced,13,HSPA8(0.949)|SQSTM1(0.903)|CTSD(0.861)|HSP90AA1(0.829)|HSP90AB1(0.829)
LATS1,large tumor suppressor kinase 1,ENSG00000131023,9113,O95835,CellAge,1,TRUE,Lats1,93.0973,TRUE,Ovary,18.94,18.94,Low tissue specificity,Cell type enhanced,10,YAP1(0.999)|NF2(0.997)|LATS2(0.989)|STK4(0.948)|CDK1(0.869)
LATS2,large tumor suppressor kinase 2,ENSG00000150457,26524,Q9NRM7,CellAge,1,TRUE,Lats2,81.3419,TRUE,Artery_Tibial,53.41,53.41,Low tissue specificity,Cell type enhanced,13,YAP1(0.999)|NF2(0.996)|LATS1(0.989)|MDM2(0.966)|STK4(0.965)
LAYN,layilin,ENSG00000204381,143903,Q6UX15,CellAge,1,TRUE,Layn,83.6898,TRUE,Cells_Cultured_fibroblasts,43.3,43.3,Low tissue specificity,Cell type enhanced,1,NF2(0.828)
LBR,lamin B receptor,ENSG00000143815,3930,Q14739,CellAge,1,TRUE,Lbr,80.3252,TRUE,Colon_Sigmoid,89.31,89.31,Low tissue specificity,Group enriched,8,LMNB1(0.999)|MECP2(0.975)|EMD(0.967)|DHCR24(0.95)|CBX5(0.927)
LCN2,lipocalin 2,ENSG00000148346,3934,P80188,CellAge,1,TRUE,Lcn2,62.1212,TRUE,Minor_Salivary_Gland,831.46,831.46,Tissue enhanced,Cell type enhanced,14,MMP9(0.998)|LRP2(0.984)|APP(0.974)|MMP2(0.907)|IL6(0.885)
LCP1,lymphocyte cytosolic protein 1,ENSG00000136167,3936,P13796,SenMayo,1,TRUE,Lcp1,96.9697,TRUE,Cells_EBV-transformed_lymphocytes,1239.14,1239.14,Tissue enhanced,Cell type enhanced,1,FSCN1(0.816)
LEO1,LEO1 component of Paf1/RNA polymerase II complex,ENSG00000166477,123169,Q8WVC0,CellAge,1,TRUE,Leo1,93.6937,TRUE,Cells_EBV-transformed_lymphocytes,53.37,53.37,Low tissue specificity,Cell type enhanced,21,SUPT5H(0.999)|ERCC6(0.985)|ELOA(0.984)|H2BC11(0.938)|H3C15(0.875)
LEP,leptin,ENSG00000174697,3952,P41159,GenAge,1,TRUE,Lep,83.2335,FALSE,Adipose_Subcutaneous,198.83,198.83,Group enriched,Group enriched,50,LEPR(0.999)|INS(0.985)|JAK2(0.966)|IRS1(0.963)|GH1(0.949)
LEPR,leptin receptor,ENSG00000116678,3953,P48357,GenAge,1,TRUE,Lepr,59.3133,TRUE,Nerve_Tibial,24.92,24.92,Tissue enriched,Cell type enhanced,22,JAK2(0.999)|LEP(0.999)|STAT3(0.921)|PTPN11(0.91)|IL6(0.902)
LGALS3,galectin 3,ENSG00000131981,3958,P17931,CellAge,1,TRUE,Lgals3,84,TRUE,Skin_Sun_Exposed_Lower_leg,627.11,627.11,Tissue enhanced,Cell type enhanced,19,ELN(0.984)|EGFR(0.964)|TLR2(0.948)|TLR4(0.938)|BCL2(0.915)
LIMA1,LIM domain and actin binding 1,ENSG00000050405,51474,Q9UHB6,CellAge,1,TRUE,Lima1,61.1331,TRUE,Cells_Cultured_fibroblasts,163.13,163.13,Low tissue specificity,Cell type enhanced,2,CTNNB1(0.931)|CDH1(0.776)
LIMK1,LIM domain kinase 1,ENSG00000106683,3984,P53667,CellAge,1,TRUE,Limk1,95.2087,TRUE,Brain_Frontal_Cortex_BA9,104.97,104.97,Tissue enhanced,Cell type enhanced,9,BMPR2(0.989)|PAK4(0.968)|PAK2(0.944)|RHOA(0.919)|HSP90AA1(0.882)
LIN52,lin-52 DREAM MuvB core complex component,ENSG00000205659,91750,Q52LA3,CellAge,1,TRUE,Lin52,100,TRUE,Brain_Cerebellar_Hemisphere,25.67,25.67,Low tissue specificity,Cell type enhanced,14,LIN54(0.999)|LIN9(0.999)|MYBL2(0.999)|RBBP4(0.999)|RBL2(0.982)
LIN54,lin-54 DREAM MuvB core complex component,ENSG00000189308,132660,Q6MZP7,CellAge,1,TRUE,Lin54,96.6622,TRUE,Cells_EBV-transformed_lymphocytes,9.6,9.6,Low tissue specificity,Cell type enhanced,12,LIN52(0.999)|LIN9(0.999)|MYBL2(0.999)|RBBP4(0.999)|RBL2(0.976)
LIN9,lin-9 DREAM MuvB core complex component,ENSG00000183814,286826,Q5TKA1,CellAge,1,TRUE,Lin9,96.8635,TRUE,Testis,8.04,8.04,Low tissue specificity,Cell type enhanced,16,LIN52(0.999)|LIN54(0.999)|MYBL2(0.999)|RBBP4(0.999)|RBL2(0.99)
LMNA,lamin A/C,ENSG00000160789,4000,P02545,CellAge|GenAge,2,TRUE,Lmna,96.6867,TRUE,Cells_Cultured_fibroblasts,392.66,392.66,Low tissue specificity,Cell type enhanced,19,EMD(0.999)|SUN1(0.997)|LMNB1(0.996)|ZMPSTE24(0.961)|SREBF1(0.935)
LMNB1,lamin B1,ENSG00000113368,4001,P20700,CellAge|GenAge|Reactome,3,TRUE,Lmnb1,96.2457,TRUE,Cells_EBV-transformed_lymphocytes,160.37,160.37,Tissue enhanced,Cell type enhanced,19,LBR(0.999)|LMNA(0.996)|EMD(0.994)|SUN1(0.982)|CDK1(0.897)
LNCTAM34A,long non coding transcriptional activator of miR34a,ENSG00000234546,102724571,,CellAge,1,FALSE,,,FALSE,Testis,6.11,6.11,,,0,
LOX,lysyl oxidase,ENSG00000113083,4015,P28300,CellAge,1,TRUE,Lox,86.3309,TRUE,Cells_Cultured_fibroblasts,296.42,296.42,Low tissue specificity,Cell type enhanced,12,ELN(0.992)|ALOX15B(0.826)|PTGS2(0.766)|CCN2(0.763)|LOXL2(0.753)
LOXL2,lysyl oxidase like 2,ENSG00000134013,4017,Q9Y4K0,CellAge,1,TRUE,Loxl2,86.4341,TRUE,Cells_Cultured_fibroblasts,188.94,188.94,Tissue enhanced,Cell type enhanced,3,SNAI1(0.973)|ELN(0.934)|LOX(0.753)
LPAR1,lysophosphatidic acid receptor 1,ENSG00000198121,1902,Q92633,CellAge,1,TRUE,Lpar1,97.2527,TRUE,Brain_Spinal_cord_cervical_c-1,238.85,238.85,Tissue enriched,Cell type enhanced,3,LPAR3(0.938)|AGT(0.92)|CXCL8(0.743)
LPAR3,lysophosphatidic acid receptor 3,ENSG00000171517,23566,Q9UBY5,CellAge,1,TRUE,Lpar3,91.5014,TRUE,Testis,17.26,17.26,Tissue enhanced,Cell type enhanced,3,LPAR1(0.938)|AGT(0.91)|CXCL8(0.711)
LRP2,LDL receptor related protein 2,ENSG00000081479,4036,P98164,GenAge,1,TRUE,Lrp2,76.7347,TRUE,Thyroid,27.36,27.36,Tissue enhanced,Cell type enriched,9,APOE(0.999)|CLU(0.994)|LCN2(0.984)|MT1E(0.871)|A2M(0.761)
LRRK2,leucine rich repeat kinase 2,ENSG00000188906,120892,Q5S007,CellAge,1,TRUE,Lrrk2,86.6245,TRUE,Lung,29.67,29.67,Tissue enriched,Group enriched,25,PARK7(0.988)|PRKN(0.986)|SFN(0.975)|HSP90AA1(0.97)|PINK1(0.955)
LY6D,lymphocyte antigen 6 family member D,ENSG00000167656,8581,Q14210,CellAge,1,FALSE,,,FALSE,Esophagus_Mucosa,2172.42,2172.42,Tissue enhanced,Group enriched,0,
MAD1L1,mitotic arrest deficient 1 like 1,ENSG00000002822,8379,Q9Y6D9,CellAge,1,TRUE,Mad1l1,80.9192,TRUE,Testis,18.87,18.87,Low tissue specificity,Cell type enhanced,18,MAD2L1(0.999)|BUB1(0.998)|BUB1B(0.993)|TTK(0.987)|BUB3(0.98)
MAD2L1,mitotic arrest deficient 2 like 1,ENSG00000164109,4085,Q13257,CellAge,1,TRUE,Mad2l1,94.1463,TRUE,Cells_EBV-transformed_lymphocytes,40.42,40.42,Tissue enhanced,Cell type enhanced,58,ANAPC10(0.999)|ANAPC4(0.999)|BUB1(0.999)|BUB1B(0.999)|BUB3(0.999)
MAEL,maelstrom spermatogenic transposon silencer,ENSG00000143194,84944,Q96JY0,CellAge,1,TRUE,Mael,89.8617,FALSE,Testis,174.21,174.21,Tissue enriched,Cell type enhanced,0,
MAF,MAF bZIP transcription factor,ENSG00000178573,4094,O75444,CellAge,1,TRUE,Maf,88.3375,TRUE,Ovary,81.01,81.01,Low tissue specificity,Cell type enhanced,9,FOS(0.998)|NFE2L2(0.998)|JUN(0.993)|NFE2L1(0.97)|CREB1(0.893)
MAGEA2,MAGE family member A2,ENSG00000268606,4101,P43356,CellAge,1,TRUE,Magea13,37.5796,TRUE,Testis,0.06,0.06,Tissue enriched,Not detected,0,
MAGOHB,"mago homolog B, exon junction complex subunit",ENSG00000111196,55110,Q96A72,CellAge,1,TRUE,Magohb,97.973,TRUE,Cells_EBV-transformed_lymphocytes,14.37,14.37,Low tissue specificity,Cell type enhanced,7,PRPF19(0.945)|SRSF1(0.87)|RAE1(0.825)|SRSF3(0.818)|HNRNPC(0.75)
MAP2K1,mitogen-activated protein kinase kinase 1,ENSG00000169032,5604,Q02750,CellAge,1,TRUE,Map2k1,98.9822,TRUE,Cells_EBV-transformed_lymphocytes,99.13,99.13,Low tissue specificity,Cell type enhanced,43,BRAF(0.999)|MAPK1(0.999)|MAPK3(0.999)|RAF1(0.999)|KSR2(0.997)
MAP2K2,mitogen-activated protein kinase kinase 2,ENSG00000126934,5605,P36507,CellAge,1,TRUE,Map2k2,88,TRUE,Testis,196.94,196.94,Low tissue specificity,Cell type enhanced,24,MAPK1(0.999)|BRAF(0.998)|MAP2K1(0.996)|RAF1(0.996)|MAPK3(0.99)
MAP2K3,mitogen-activated protein kinase kinase 3,ENSG00000034152,5606,P46734,CellAge|Reactome,2,TRUE,Map2k3,96.5418,FALSE,Whole_Blood,171.08,171.08,Tissue enhanced,Cell type enhanced,18,MAPK14(0.999)|MAP2K6(0.989)|MAP3K5(0.988)|MAPK3(0.98)|MAPK1(0.977)
MAP2K4,mitogen-activated protein kinase kinase 4,ENSG00000065559,6416,P45985,Reactome,1,TRUE,Map2k4,97.7444,TRUE,Brain_Frontal_Cortex_BA9,62.99,62.99,Low tissue specificity,Cell type enhanced,16,MAPK8(0.999)|MAPK9(0.999)|MAP3K5(0.998)|MAP3K7(0.998)|MAPK14(0.987)
MAP2K6,mitogen-activated protein kinase kinase 6,ENSG00000108984,5608,P52564,CellAge|Reactome,2,TRUE,Map2k6,97.9042,TRUE,Cells_EBV-transformed_lymphocytes,19.08,19.08,Tissue enhanced,Cell type enhanced,16,MAPK14(0.997)|MAP3K7(0.996)|MAP3K5(0.993)|MAP2K3(0.989)|MAPK12(0.98)
MAP2K7,mitogen-activated protein kinase kinase 7,ENSG00000076984,5609,O14733,CellAge|Reactome,2,TRUE,Map2k7,98.8067,TRUE,Brain_Cerebellum,66.06,66.06,Low tissue specificity,Low cell type specificity,11,MAPK8(0.996)|MAP3K7(0.987)|MAPK9(0.976)|MAP3K5(0.964)|MAP2K4(0.956)
MAP3K14,mitogen-activated protein kinase kinase kinase 14,ENSG00000006062,9020,Q99558,CellAge,1,TRUE,Map3k14,84.2661,TRUE,Colon_Sigmoid,34.35,34.35,Low tissue specificity,Low cell type specificity,9,CHUK(0.997)|IKBKG(0.994)|IKBKB(0.991)|NFKB2(0.966)|MAP3K7(0.959)
MAP3K5,mitogen-activated protein kinase kinase kinase 5,ENSG00000197442,4217,Q99683,CellAge|GenAge|Reactome,3,TRUE,Map3k5,94.687,TRUE,Adrenal_Gland,137.49,137.49,Tissue enhanced,Cell type enhanced,33,TXN(0.999)|MAP2K4(0.998)|MAP2K6(0.993)|PARK7(0.991)|MAP2K3(0.988)
MAP3K6,mitogen-activated protein kinase kinase kinase 6,ENSG00000142733,9064,O95382,CellAge,1,TRUE,Map3k6,87.1894,TRUE,Skin_Sun_Exposed_Lower_leg,118.18,118.18,Low tissue specificity,Cell type enhanced,3,MAP2K3(0.931)|MAP2K6(0.92)|MAP3K5(0.801)
MAP3K7,mitogen-activated protein kinase kinase kinase 7,ENSG00000135341,6885,O43318,CellAge,1,TRUE,Map3k7,94.8845,TRUE,Cells_Cultured_fibroblasts,29.63,29.63,Low tissue specificity,Low cell type specificity,46,IKBKG(0.999)|MYD88(0.999)|TNF(0.999)|TNFRSF1A(0.999)|MAP2K4(0.998)
MAP4K1,mitogen-activated protein kinase kinase kinase kinase 1,ENSG00000104814,11184,Q92918,CellAge,1,TRUE,Map4k1,86.2363,TRUE,Cells_EBV-transformed_lymphocytes,160.02,160.02,Tissue enhanced,Cell type enhanced,2,GRB2(0.958)|EGFR(0.747)
MAP4K4,mitogen-activated protein kinase kinase kinase kinase 4,ENSG00000071054,9448,O95819,Reactome,1,TRUE,Map4k4,87.7168,TRUE,Brain_Spinal_cord_cervical_c-1,207.62,207.62,Tissue enhanced,Cell type enhanced,1,MINK1(0.883)
MAPK1,mitogen-activated protein kinase 1,ENSG00000100030,5594,P28482,CellAge|Reactome,2,TRUE,Mapk1,98.6111,TRUE,Brain_Nucleus_accumbens_basal_ganglia,62.45,62.45,Low tissue specificity,Cell type enhanced,102,MAP2K1(0.999)|MAP2K2(0.999)|RPS6KA1(0.999)|JUN(0.998)|PEA15(0.998)
MAPK10,mitogen-activated protein kinase 10,ENSG00000109339,5602,P53779,Reactome,1,TRUE,Mapk10,87.5,TRUE,Brain_Frontal_Cortex_BA9,40.53,40.53,Tissue enhanced,Cell type enhanced,0,
MAPK11,mitogen-activated protein kinase 11,ENSG00000185386,5600,Q15759,Reactome,1,TRUE,Mapk11,97.2527,TRUE,Brain_Cerebellum,105.53,105.53,Tissue enhanced,Cell type enhanced,48,MAPKAPK2(0.997)|MAPKAPK3(0.994)|ATF2(0.993)|MAP2K6(0.977)|MAP2K3(0.976)
MAPK12,mitogen-activated protein kinase 12,ENSG00000188130,6300,P53778,CellAge,1,TRUE,Mapk12,92.6431,TRUE,Muscle_Skeletal,84.34,84.34,Group enriched,Cell type enhanced,48,MAP2K6(0.98)|MAPKAPK2(0.974)|DUSP1(0.972)|JUN(0.971)|MAP2K3(0.969)
MAPK14,mitogen-activated protein kinase 14,ENSG00000112062,1432,Q16539,CellAge|GenAge|Reactome,3,TRUE,Mapk14,93.8889,TRUE,Whole_Blood,72.37,72.37,Low tissue specificity,Group enriched,73,MAP2K3(0.999)|MAPKAPK2(0.999)|ATF2(0.998)|DUSP1(0.998)|MAP2K6(0.997)
MAPK3,mitogen-activated protein kinase 3,ENSG00000102882,5595,P27361,GenAge|Reactome,2,TRUE,Mapk3,96.8338,TRUE,Brain_Cortex,123.15,123.15,Low tissue specificity,Cell type enhanced,115,MAP2K1(0.999)|DUSP1(0.996)|FOS(0.994)|MAPK1(0.994)|TP53(0.994)
MAPK7,mitogen-activated protein kinase 7,ENSG00000166484,5598,Q13164,Reactome,1,TRUE,Mapk7,91.7892,TRUE,Cervix_Ectocervix,45.95,45.95,Low tissue specificity,Cell type enhanced,8,MEF2A(0.972)|RPS6KA3(0.951)|NFE2L2(0.947)|GJA1(0.941)|RPS6KA1(0.927)
MAPK8,mitogen-activated protein kinase 8,ENSG00000107643,5599,P45983,GenAge|Reactome,2,TRUE,Mapk8,97.1897,TRUE,Brain_Cerebellar_Hemisphere,32.16,32.16,Low tissue specificity,Low cell type specificity,81,JUN(0.999)|MAP2K4(0.999)|MAPK9(0.999)|ATF2(0.998)|DUSP16(0.998)
MAPK9,mitogen-activated protein kinase 9,ENSG00000050748,5601,P45984,CellAge|GenAge|Reactome,3,TRUE,Mapk9,98.8208,TRUE,Brain_Cerebellar_Hemisphere,91.75,91.75,Low tissue specificity,Low cell type specificity,48,JUN(0.999)|MAP2K4(0.999)|MAPK8(0.999)|JUND(0.987)|DUSP16(0.985)
MAPKAPK2,MAPK activated protein kinase 2,ENSG00000162889,9261,P49137,Reactome,1,TRUE,Mapkapk2,92.5,TRUE,Lung,116.57,116.57,Low tissue specificity,Cell type enhanced,13,HSPB1(0.999)|MAPK14(0.999)|MAPK11(0.997)|ZFP36(0.979)|MAPK12(0.974)
MAPKAPK3,MAPK activated protein kinase 3,ENSG00000114738,7867,Q16644,Reactome,1,TRUE,Mapkapk3,94.7644,TRUE,Heart_Left_Ventricle,119.51,119.51,Tissue enhanced,Cell type enhanced,7,MAPK14(0.996)|MAPK11(0.994)|HSPB1(0.979)|MAPKAPK2(0.974)|MAPK12(0.967)
MAPKAPK5,MAPK activated protein kinase 5,ENSG00000089022,8550,Q8IW41,CellAge|Reactome,2,TRUE,Mapkapk5,97.2399,TRUE,Brain_Cerebellar_Hemisphere,16.14,16.14,Low tissue specificity,Low cell type specificity,8,HSPB1(0.995)|MAPK12(0.966)|MAPK14(0.956)|MAPK11(0.953)|MYC(0.803)
MAPT,microtubule associated protein tau,ENSG00000186868,4137,P10636,GenAge,1,TRUE,Mapt,58.5834,TRUE,Brain_Cerebellum,223.01,223.01,Tissue enhanced,Group enriched,39,CDK5(0.999)|GSK3B(0.999)|APP(0.995)|APOE(0.991)|YWHAZ(0.974)
MARCHF5,membrane associated ring-CH-type finger 5,ENSG00000198060,54708,Q9NX47,CellAge,1,TRUE,Marchf5,100,TRUE,Ovary,31.7,31.7,Low tissue specificity,Cell type enhanced,4,FIS1(0.965)|MAVS(0.853)|UBE2E1(0.783)|PRKN(0.717)
MARCKS,myristoylated alanine rich protein kinase C substrate,ENSG00000277443,4082,P29966,CellAge,1,TRUE,Marcks,67.4699,TRUE,Brain_Cerebellar_Hemisphere,189.59,189.59,Low tissue specificity,Cell type enhanced,2,PRKCD(0.952)|PRKCA(0.908)
MAST1,microtubule associated serine/threonine kinase 1,ENSG00000105613,22983,Q9Y2H9,CellAge,1,TRUE,Mast1,94.3949,TRUE,Brain_Cerebellum,187.1,187.1,Tissue enriched,Cell type enhanced,0,
MATK,megakaryocyte-associated tyrosine kinase,ENSG00000007264,4145,P42679,CellAge,1,TRUE,Matk,82.4458,TRUE,Brain_Frontal_Cortex_BA9,36.11,36.11,Tissue enhanced,Group enriched,3,ERBB2(0.898)|CD34(0.767)|PTK2B(0.762)
MAVS,mitochondrial antiviral signaling protein,ENSG00000088888,57506,Q7Z434,CellAge,1,TRUE,Mavs,49.2593,TRUE,Ovary,40.81,40.81,Low tissue specificity,Cell type enhanced,33,ATG12(0.999)|ATG5(0.999)|NLRX1(0.999)|TBK1(0.999)|IRF3(0.998)
MAX,MYC associated transcriptional regulator X,ENSG00000125952,4149,P61244,GenAge,1,TRUE,Max,93.75,FALSE,Fallopian_Tube,87.96,87.96,Low tissue specificity,Cell type enhanced,21,MXD1(0.999)|MYC(0.999)|MXI1(0.998)|MYCN(0.996)|MAPK14(0.976)
MCAM,melanoma cell adhesion molecule,ENSG00000076706,4162,P43121,CellAge,1,TRUE,Mcam,76.4706,TRUE,Artery_Tibial,1868.81,1868.81,Group enriched,Cell type enhanced,5,KDR(0.941)|PECAM1(0.852)|ENG(0.834)|CD34(0.789)|WNT5A(0.769)
MCL1,"MCL1 apoptosis regulator, BCL2 family member",ENSG00000143384,4170,Q07820,CellAge,1,TRUE,Mcl1,76.2857,TRUE,Lung,474.74,474.74,Tissue enhanced,Cell type enhanced,35,BAX(0.999)|BAK1(0.998)|BECN1(0.998)|BCL2L1(0.989)|ATG12(0.988)
MCM3AP,minichromosome maintenance complex component 3 associated protein,ENSG00000160294,8888,O60318,CellAge,1,TRUE,Mcm3ap,78.4343,TRUE,Cells_EBV-transformed_lymphocytes,52.92,52.92,Low tissue specificity,Low cell type specificity,4,TPR(0.964)|MAD1L1(0.939)|MAD2L1(0.902)|RAE1(0.715)
MCM7,minichromosome maintenance complex component 7,ENSG00000166508,4176,P33993,CellAge,1,TRUE,Mcm7,92.7677,TRUE,Cells_EBV-transformed_lymphocytes,196.21,196.21,Tissue enhanced,Cell type enhanced,44,CDC45(0.999)|CDC6(0.999)|CDC7(0.999)|ORC1(0.997)|TIMELESS(0.996)
MCRS1,microspherule protein 1,ENSG00000187778,10445,Q96EZ8,CellAge,1,TRUE,Mcrs1,90.6926,TRUE,Thyroid,77.37,77.37,Low tissue specificity,Low cell type specificity,13,OGT(0.99)|RUVBL2(0.977)|YY1(0.966)|KAT5(0.942)|TRRAP(0.908)
MCU,mitochondrial calcium uniporter,ENSG00000156026,90550,Q8NE86,CellAge,1,TRUE,Mcu,96.0114,TRUE,Brain_Cerebellar_Hemisphere,52.04,52.04,Tissue enhanced,Cell type enhanced,4,ITPR1(0.887)|ITPR3(0.884)|HSPA9(0.845)|PHB2(0.732)
MDC1,mediator of DNA damage checkpoint 1,ENSG00000228575,9656,Q14676,CellAge,1,FALSE,,,FALSE,,,,,,42,ATM(0.999)|BRCA1(0.999)|H2AX(0.999)|TP53BP1(0.999)|TOPBP1(0.995)
MDH1,malate dehydrogenase 1,ENSG00000014641,4190,P40925,CellAge,1,TRUE,Mdh1,96.4072,TRUE,Heart_Left_Ventricle,439.98,439.98,Tissue enhanced,Cell type enhanced,0,
MDK,midkine,ENSG00000110492,4192,P21741,CellAge,1,TRUE,Mdk,86.014,TRUE,Ovary,399.5,399.5,Tissue enhanced,Cell type enhanced,1,SDC1(0.825)
MDM2,MDM2 proto-oncogene,ENSG00000135679,4193,Q00987,CellAge|GenAge|Reactome,3,TRUE,Mdm2,80.4829,TRUE,Cells_Cultured_fibroblasts,32.49,32.49,Low tissue specificity,Cell type enhanced,111,AKT1(0.999)|CDKN2A(0.999)|EP300(0.999)|MDM4(0.999)|RB1(0.999)
MDM4,MDM4 regulator of p53,ENSG00000198625,4194,O15151,Reactome,1,TRUE,Mdm4,84.0816,TRUE,Ovary,30.62,30.62,Low tissue specificity,Low cell type specificity,22,MDM2(0.999)|TP53(0.999)|SFN(0.977)|CSNK1A1(0.971)|RPS27A(0.97)
MDP1,magnesium dependent phosphatase 1,ENSG00000285200,145553,Q86V88,CellAge,1,FALSE,,,FALSE,,,,,,0,
ME1,malic enzyme 1,ENSG00000065833,4199,P48163,CellAge,1,TRUE,Me1,90.035,TRUE,Adrenal_Gland,71.57,71.57,Low tissue specificity,Cell type enhanced,4,ME2(0.906)|NFE2L2(0.849)|G6PD(0.794)|ACLY(0.761)
ME2,malic enzyme 2,ENSG00000082212,4200,P23368,CellAge,1,TRUE,Me2,89.0411,TRUE,Cells_EBV-transformed_lymphocytes,29.06,29.06,Tissue enhanced,Cell type enhanced,1,ME1(0.906)
MECP2,methyl-CpG binding protein 2,ENSG00000169057,4204,P51608,CellAge,1,TRUE,Mecp2,91.1647,TRUE,Brain_Cerebellar_Hemisphere,38.8,38.8,Low tissue specificity,Cell type enhanced,44,HDAC1(0.999)|SIN3A(0.999)|DNMT1(0.998)|HDAC2(0.997)|NCOR1(0.997)
MED1,mediator complex subunit 1,ENSG00000125686,5469,Q15648,GenAge,1,TRUE,Med1,94.3074,TRUE,Cells_Cultured_fibroblasts,32.87,32.87,Low tissue specificity,Low cell type specificity,50,MED12(0.999)|PPARG(0.999)|ESR1(0.998)|STN1(0.994)|RPL11(0.984)
MED12,mediator complex subunit 12,ENSG00000184634,9968,Q93074,CellAge,1,TRUE,Med12,97.2898,TRUE,Ovary,54.51,54.51,Low tissue specificity,Cell type enhanced,9,MED1(0.999)|STN1(0.994)|EHMT2(0.925)|CTNNB1(0.854)|EP300(0.805)
MEF2A,myocyte enhancer factor 2A,ENSG00000068305,4205,Q02078,CellAge,1,TRUE,Mef2a,88.5149,TRUE,Artery_Aorta,77.95,77.95,Low tissue specificity,Cell type enhanced,12,EP300(0.989)|HDAC4(0.973)|MAPK7(0.972)|MAPK14(0.962)|HDAC7(0.959)
MEIS2,Meis homeobox 2,ENSG00000134138,4212,O14770,CellAge,1,TRUE,Meis2,99.5807,TRUE,Uterus,52.07,52.07,Tissue enhanced,Cell type enhanced,0,
MEN1,menin 1,ENSG00000133895,4221,O00255,CellAge,1,TRUE,Men1,96.5574,TRUE,Brain_Cerebellum,45.14,45.14,Low tissue specificity,Cell type enhanced,19,JUND(0.998)|SMAD3(0.983)|CTNNB1(0.978)|DPY30(0.925)|ESR1(0.923)
MEOX1,mesenchyme homeobox 1,ENSG00000005102,4222,P50221,CellAge,1,TRUE,Meox1,81.4961,TRUE,Adipose_Subcutaneous,54.52,54.52,Tissue enhanced,Cell type enriched,1,SIX1(0.714)
MET,"MET proto-oncogene, receptor tyrosine kinase",ENSG00000105976,4233,P08581,CellAge,1,TRUE,Met,88.9209,TRUE,Nerve_Tibial,21.26,21.26,Tissue enhanced,Cell type enhanced,56,GRB2(0.999)|HGF(0.999)|EGFR(0.996)|SRC(0.993)|SHC1(0.992)
METTL14,"methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit",ENSG00000145388,57721,Q9HCE5,CellAge,1,TRUE,Mettl14,98.6842,TRUE,Testis,14.92,14.92,Low tissue specificity,Cell type enhanced,6,DGCR8(0.989)|SMAD2(0.981)|HNRNPC(0.857)|ERCC3(0.854)|SMAD3(0.79)
MIF,macrophage migration inhibitory factor,ENSG00000240972,4282,P14174,CellAge|GenAge|SenMayo,3,TRUE,Mif,86.087,TRUE,Testis,29.05,29.05,Low tissue specificity,Cell type enhanced,8,CXCR2(0.993)|CCL2(0.836)|CCL5(0.756)|SOD1(0.744)|CXCL12(0.737)
MINK1,misshapen like kinase 1,ENSG00000141503,50488,Q8N4C8,CellAge|Reactome,2,TRUE,Mink1,94.7447,TRUE,Skin_Sun_Exposed_Lower_leg,168.89,168.89,Low tissue specificity,Cell type enhanced,2,MAP4K4(0.883)|TNIK(0.774)
MITF,melanocyte inducing transcription factor,ENSG00000187098,4286,O75030,CellAge,1,TRUE,Mitf,94.4867,TRUE,Cervix_Ectocervix,70.76,70.76,Low tissue specificity,Cell type enhanced,10,SPI1(0.968)|MAPK3(0.94)|MAPK1(0.932)|JUN(0.923)|FOS(0.92)
MKRN1,makorin ring finger protein 1,ENSG00000133606,23608,Q9UHC7,CellAge,1,TRUE,Mkrn1,93.5685,TRUE,Testis,113.45,113.45,Low tissue specificity,Cell type enhanced,1,TERT(0.868)
MLH1,mutL homolog 1,ENSG00000076242,4292,P40692,GenAge,1,TRUE,Mlh1,88.7566,TRUE,Cells_EBV-transformed_lymphocytes,48.52,48.52,Low tissue specificity,Low cell type specificity,38,BLM(0.999)|BRIP1(0.999)|ATM(0.997)|BRCA1(0.994)|FANCD2(0.971)
MME,membrane metalloendopeptidase,ENSG00000196549,4311,P08473,CellAge,1,TRUE,Mme,94.1333,TRUE,Cells_Cultured_fibroblasts,640.48,640.48,Tissue enhanced,Cell type enhanced,12,DPP4(0.962)|AGT(0.957)|BCL6(0.926)|CD9(0.867)|APP(0.857)
MMP1,matrix metallopeptidase 1,ENSG00000196611,4312,P03956,SenMayo,1,TRUE,Mmp1a,58.6354,TRUE,Cells_Cultured_fibroblasts,51.85,51.85,Tissue enhanced,Cell type enhanced,30,MMP3(0.985)|MMP9(0.974)|TIMP2(0.936)|MMP2(0.93)|MMP7(0.878)
MMP10,matrix metallopeptidase 10,ENSG00000166670,4319,P09238,SenMayo,1,FALSE,,,TRUE,Testis,1.16,1.16,Tissue enriched,Cell type enhanced,7,TIMP2(0.981)|MMP3(0.973)|MMP7(0.85)|HDAC7(0.807)|MMP1(0.789)
MMP12,matrix metallopeptidase 12,ENSG00000262406,4321,P39900,SenMayo,1,TRUE,Mmp12,61.7021,TRUE,Small_Intestine_Terminal_Ileum,3.83,3.83,Tissue enhanced,Cell type enriched,9,ELN(0.958)|MMP3(0.764)|IL1B(0.759)|CCL2(0.75)|IL6(0.743)
MMP13,matrix metallopeptidase 13,ENSG00000137745,4322,P45452,SenMayo,1,TRUE,Mmp13,86.6242,TRUE,Pituitary,0.64,0.64,Tissue enriched,Cell type enhanced,10,TIMP2(0.963)|MMP14(0.828)|IL1B(0.823)|COL18A1(0.81)|A2M(0.786)
MMP14,matrix metallopeptidase 14,ENSG00000157227,4323,P50281,SenMayo,1,TRUE,Mmp14,96.5636,TRUE,Cells_Cultured_fibroblasts,620.19,620.19,Low tissue specificity,Cell type enhanced,9,TIMP2(0.999)|MMP2(0.997)|RECK(0.894)|MMP9(0.831)|MMP13(0.828)
MMP2,matrix metallopeptidase 2,ENSG00000087245,4313,P08253,SenMayo,1,TRUE,Mmp2,95.9091,TRUE,Cells_Cultured_fibroblasts,908.42,908.42,Tissue enhanced,Cell type enhanced,53,TIMP2(0.999)|MMP14(0.997)|SRC(0.972)|TGFB1(0.962)|MMP7(0.961)
MMP3,matrix metallopeptidase 3,ENSG00000149968,4314,P08254,SenMayo,1,TRUE,Mmp3,76.7296,TRUE,Minor_Salivary_Gland,176.91,176.91,Tissue enhanced,Cell type enhanced,35,SPP1(0.997)|MMP1(0.985)|MMP10(0.973)|TIMP2(0.967)|MMP9(0.956)
MMP7,matrix metallopeptidase 7,ENSG00000137673,4316,P09237,CellAge,1,TRUE,Mmp7,69.2884,TRUE,Minor_Salivary_Gland,251.01,251.01,Tissue enhanced,Cell type enhanced,18,MMP2(0.961)|TIMP2(0.951)|SPP1(0.941)|MMP9(0.883)|MMP1(0.878)
MMP9,matrix metallopeptidase 9,ENSG00000100985,4318,P14780,CellAge|SenMayo,2,TRUE,Mmp9,74.3989,TRUE,Whole_Blood,550.48,550.48,Group enriched,Group enriched,87,LCN2(0.998)|TIMP2(0.998)|ELN(0.979)|MMP1(0.974)|SRC(0.97)
MNX1,motor neuron and pancreas homeobox 1,ENSG00000130675,3110,P50219,CellAge,1,TRUE,Mnx1,89.7756,TRUE,Pancreas,7.73,7.73,Group enriched,Cell type enhanced,1,GDF11(0.765)
MOB3A,MOB kinase activator 3A,ENSG00000172081,126308,Q96BX8,CellAge,1,TRUE,Mob3a,94.47,TRUE,Cells_EBV-transformed_lymphocytes,230.62,230.62,Low tissue specificity,Cell type enhanced,0,
MORC3,MORC family CW-type zinc finger 3,ENSG00000159256,23515,Q14149,CellAge,1,TRUE,Morc3,82.9606,TRUE,Ovary,42.77,42.77,Low tissue specificity,Low cell type specificity,4,H3C1(0.925)|H3-4(0.919)|H3-3A(0.908)|H3C15(0.905)
MORF4L1,mortality factor 4 like 1,ENSG00000185787,10933,Q9UBU8,CellAge,1,TRUE,Morf4l1,100,TRUE,Artery_Aorta,277.21,277.21,Low tissue specificity,Cell type enhanced,29,KAT5(0.999)|YEATS4(0.999)|HDAC2(0.998)|TRRAP(0.998)|EP400(0.997)
MOS,"MOS proto-oncogene, serine/threonine kinase",ENSG00000172680,4342,P00540,CellAge,1,TRUE,Mos,73.4104,TRUE,Testis,1.68,1.68,Not detected,Cell type enhanced,5,MAP2K1(0.934)|MAP2K2(0.934)|HSP90AA1(0.928)|HSP90AB1(0.928)|CPEB1(0.749)
MOV10,Mov10 RNA helicase,ENSG00000155363,4343,Q9HCE1,Reactome,1,TRUE,Mov10,90.8275,TRUE,Testis,69.03,69.03,Low tissue specificity,Cell type enhanced,13,AGO2(0.997)|DICER1(0.991)|AGO1(0.988)|TNRC6B(0.988)|CBX6(0.88)
MRE11,MRE11 double strand break repair nuclease,ENSG00000020922,4361,P49959,Reactome,1,TRUE,Mre11a,88.2768,TRUE,Cells_EBV-transformed_lymphocytes,22.19,22.19,Low tissue specificity,Low cell type specificity,46,ATM(0.999)|BRCA1(0.999)|NBN(0.999)|RAD50(0.999)|BRIP1(0.998)
MRTFA,myocardin related transcription factor A,ENSG00000196588,57591,Q969V6,CellAge,1,TRUE,Mrtfa,79.2435,TRUE,Testis,51.89,51.89,Low tissue specificity,Cell type enhanced,4,SRF(0.999)|RHOA(0.887)|SMARCA4(0.743)|EP300(0.71)
MRTFB,myocardin related transcription factor B,ENSG00000186260,57496,Q9ULH7,CellAge,1,TRUE,Mrtfb,83.8035,FALSE,Adipose_Subcutaneous,36.18,36.18,Low tissue specificity,Cell type enhanced,2,SRF(0.978)|RHOA(0.806)
MSN,moesin,ENSG00000147065,4478,P26038,CellAge,1,TRUE,Msn,98.6135,TRUE,Lung,365.94,365.94,Low tissue specificity,Cell type enhanced,12,ICAM1(0.991)|LRRK2(0.952)|RHOA(0.899)|ICAM3(0.829)|GRB2(0.809)
MSRA,methionine sulfoxide reductase A,ENSG00000175806,4482,Q9UJ68,GenAge,1,TRUE,Msra,73.617,FALSE,Brain_Cerebellar_Hemisphere,28.8,28.8,Tissue enhanced,Cell type enhanced,1,TXN(0.953)
MST1,macrophage stimulating 1,ENSG00000173531,4485,P26927,CellAge,1,TRUE,Mst1,78.6207,TRUE,Liver,395.84,395.84,Tissue enriched,Cell type enriched,1,MET(0.758)
MT-CO1,cytochrome c oxidase subunit I,ENSG00000198804,4512,P00395,GenAge,1,TRUE,mt-Co1,90.8382,TRUE,Heart_Left_Ventricle,82348.1,82348.1,Tissue enhanced,Cell type enhanced,8,COX5B(0.999)|SDHC(0.951)|PPARGC1A(0.8)|EEF1A1(0.774)|PRODH(0.735)
MT1E,metallothionein 1E,ENSG00000169715,4493,P04732,GenAge,1,FALSE,,,TRUE,Cells_Cultured_fibroblasts,694.1,694.1,Tissue enhanced,Cell type enhanced,3,LRP2(0.871)|MT1G(0.795)|GSR(0.717)
MT1G,metallothionein 1G,ENSG00000125144,4495,P13640,CellAge,1,FALSE,,,TRUE,Liver,1158.38,1158.38,Tissue enhanced,Cell type enhanced,1,MT1E(0.795)
MTDH,metadherin,ENSG00000147649,92140,Q86UE4,CellAge,1,TRUE,Mtdh,91.0653,TRUE,Cells_EBV-transformed_lymphocytes,134.72,134.72,Low tissue specificity,Low cell type specificity,3,AGO2(0.859)|TYMS(0.785)|AKT1(0.701)
MTHFD2,"methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase",ENSG00000065911,10797,P13995,CellAge,1,TRUE,Mthfd2,92,FALSE,Cells_EBV-transformed_lymphocytes,163.05,163.05,Low tissue specificity,Cell type enhanced,3,TYMS(0.994)|GMPS(0.778)|PHGDH(0.722)
MTOR,mechanistic target of rapamycin kinase,ENSG00000198793,2475,P42345,CellAge|GenAge,2,TRUE,Mtor,98.9408,TRUE,Testis,35.51,35.51,Low tissue specificity,Low cell type specificity,75,AKT1(0.999)|AKT1S1(0.999)|DEPTOR(0.999)|EIF4EBP1(0.999)|RICTOR(0.999)
MUC4,"mucin 4, cell surface associated",ENSG00000277585,4585,Q99102,CellAge,1,FALSE,,,FALSE,,,,,,2,ERBB2(0.996)|EGFR(0.875)
MUS81,MUS81 structure-specific endonuclease subunit,ENSG00000172732,80198,Q96NY9,CellAge,1,TRUE,Mus81,81.8512,TRUE,Uterus,79.75,79.75,Low tissue specificity,Cell type enhanced,33,ERCC1(0.998)|ERCC4(0.994)|RAD51(0.986)|RAD52(0.976)|WRN(0.966)
MVK,mevalonate kinase,ENSG00000110921,4598,Q03426,CellAge,1,TRUE,Mvk,80.5556,TRUE,Testis,41.6,41.6,Tissue enhanced,Cell type enhanced,7,HMGCR(0.999)|PMVK(0.994)|FDPS(0.911)|CTH(0.902)|DHCR24(0.741)
MVP,major vault protein,ENSG00000013364,9961,Q14764,CellAge,1,TRUE,Mvp,88.1299,TRUE,Adrenal_Gland,184.92,184.92,Low tissue specificity,Cell type enhanced,4,PTEN(0.786)|PARP1(0.77)|ABCB1(0.76)|MYD88(0.724)
MXD1,MAX dimerization protein 1,ENSG00000059728,4084,Q05195,GenAge,1,TRUE,Mxd1,88.2353,TRUE,Whole_Blood,348.82,348.82,Tissue enhanced,Group enriched,4,MAX(0.999)|SIN3A(0.996)|MYC(0.919)|AKT1(0.744)
MXD4,MAX dimerization protein 4,ENSG00000123933,10608,Q14582,CellAge,1,TRUE,Mxd4,91.866,TRUE,Brain_Cerebellum,240.84,240.84,Low tissue specificity,Low cell type specificity,2,MAX(0.897)|SIN3A(0.785)
MXI1,"MAX interactor 1, dimerization protein",ENSG00000119950,4601,P50539,GenAge,1,TRUE,Mxi1,70.5085,TRUE,Artery_Tibial,141.34,141.34,Low tissue specificity,Cell type enhanced,10,MAX(0.998)|ANAPC4(0.994)|BUB1B(0.994)|CDC27(0.994)|MYC(0.904)
MYBBP1A,MYB binding protein 1a,ENSG00000132382,10514,Q9BQG0,CellAge,1,TRUE,Mybbp1a,69.1265,TRUE,Cells_EBV-transformed_lymphocytes,56.48,56.48,Low tissue specificity,Low cell type specificity,11,PDCD11(0.949)|PES1(0.948)|DEK(0.932)|SIRT7(0.89)|ERCC6(0.853)
MYBL2,MYB proto-oncogene like 2,ENSG00000101057,4605,P10244,CellAge,1,TRUE,Mybl2,85.2857,TRUE,Cells_EBV-transformed_lymphocytes,163.22,163.22,Group enriched,Cell type enhanced,31,LIN52(0.999)|LIN54(0.999)|LIN9(0.999)|FOXM1(0.998)|RBBP4(0.997)
MYC,"MYC proto-oncogene, bHLH transcription factor",ENSG00000136997,4609,P01106,CellAge|GenAge,2,TRUE,Myc,90.0881,TRUE,Skin_Not_Sun_Exposed_Suprapubic,298.82,298.82,Tissue enhanced,Cell type enhanced,206,BIN1(0.999)|BRCA1(0.999)|EP300(0.999)|MAX(0.999)|TRRAP(0.999)
MYCN,"MYCN proto-oncogene, bHLH transcription factor",ENSG00000134323,4613,P04198,CellAge,1,TRUE,Mycn,85.1293,TRUE,Nerve_Tibial,7.52,7.52,Tissue enhanced,Cell type enriched,28,AURKA(0.998)|MAX(0.996)|EZH2(0.952)|NDRG1(0.937)|MYC(0.933)
MYD88,MYD88 innate immune signal transduction adaptor,ENSG00000172936,4615,Q99836,CellAge,1,TRUE,Myd88,81.7568,TRUE,Whole_Blood,199.54,199.54,Low tissue specificity,Cell type enhanced,61,IKBKG(0.999)|IL1B(0.999)|IL1R1(0.999)|IRAK4(0.999)|IRF7(0.999)
MYLK,myosin light chain kinase,ENSG00000065534,4638,Q15746,CellAge,1,TRUE,Mylk,85.4754,TRUE,Esophagus_Muscularis,441.2,441.2,Tissue enhanced,Cell type enhanced,1,PAK2(0.766)
NACC1,nucleus accumbens associated 1,ENSG00000160877,112939,Q96RE7,CellAge,1,TRUE,Nacc1,87.666,TRUE,Cells_Cultured_fibroblasts,65.02,65.02,Low tissue specificity,Cell type enhanced,4,HDAC4(0.874)|NANOG(0.777)|POU5F1(0.743)|SOX2(0.702)
NADK,NAD kinase,ENSG00000008130,65220,O95544,CellAge,1,TRUE,Nadk,91.0314,TRUE,Whole_Blood,112.69,112.69,Low tissue specificity,Group enriched,1,G6PD(0.917)
NAMPT,nicotinamide phosphoribosyltransferase,ENSG00000105835,10135,P43490,CellAge,1,TRUE,Nampt,95.723,TRUE,Whole_Blood,522.38,522.38,Tissue enhanced,Cell type enriched,13,SIRT1(0.993)|SIRT3(0.97)|SIRT6(0.964)|SIRT2(0.958)|SIRT7(0.948)
NANOG,Nanog homeobox,ENSG00000111704,79923,Q9H9S0,CellAge,1,TRUE,Nanog,54.0984,TRUE,Testis,0.17,0.17,Not detected,Cell type enhanced,45,POU5F1(0.999)|SOX2(0.999)|STAT3(0.995)|KLF4(0.994)|SALL1(0.972)
NAP1L4,nucleosome assembly protein 1 like 4,ENSG00000273562,4676,Q99733,SenMayo,1,FALSE,,,FALSE,,,,,,4,H2BC21(0.799)|NPM1(0.751)|PES1(0.73)|CDKN1C(0.701)
NBN,nibrin,ENSG00000104320,4683,O60934,CellAge|GenAge|Reactome,3,TRUE,Nbn,70.2918,TRUE,Cells_EBV-transformed_lymphocytes,67.16,67.16,Low tissue specificity,Cell type enhanced,34,ATM(0.999)|MRE11(0.999)|RAD50(0.999)|BRIP1(0.998)|MDC1(0.994)
NBR1,NBR1 autophagy cargo receptor,ENSG00000188554,4077,Q14596,CellAge,1,TRUE,Nbr1,84.9896,TRUE,Testis,150.64,150.64,Low tissue specificity,Cell type enriched,19,SQSTM1(0.999)|UBC(0.989)|RPS27A(0.973)|UBB(0.963)|PEX5(0.957)
NCAPG2,non-SMC condensin II complex subunit G2,ENSG00000146918,54892,Q86XI2,CellAge,1,TRUE,Ncapg2,81.1024,TRUE,Cells_EBV-transformed_lymphocytes,35.11,35.11,Tissue enhanced,Cell type enhanced,17,NCAPH2(0.999)|SMC2(0.994)|PLK1(0.919)|KIF11(0.848)|TPX2(0.807)
NCAPH2,non-SMC condensin II complex subunit H2,ENSG00000025770,29781,Q6IBW4,CellAge,1,TRUE,Ncaph2,74.3802,TRUE,Testis,92.75,92.75,Low tissue specificity,Cell type enhanced,3,NCAPG2(0.999)|SMC2(0.99)|TERF1(0.713)
NCOR1,nuclear receptor corepressor 1,ENSG00000141027,9611,O75376,GenAge,1,TRUE,Ncor1,92.1721,TRUE,Uterus,34.98,34.98,Low tissue specificity,Low cell type specificity,67,BCL6(0.999)|ESR1(0.999)|HDAC1(0.999)|HDAC3(0.999)|HDAC4(0.999)
NCOR2,nuclear receptor corepressor 2,ENSG00000196498,9612,Q9Y618,GenAge,1,TRUE,Ncor2,86.7542,TRUE,Pituitary,103.15,103.15,Low tissue specificity,Low cell type specificity,42,BCL6(0.999)|HDAC1(0.999)|HDAC3(0.999)|HDAC4(0.999)|PPARG(0.999)
NDRG1,N-myc downstream regulated 1,ENSG00000104419,10397,Q92597,CellAge,1,TRUE,Ndrg1,93.6548,TRUE,Nerve_Tibial,816.82,816.82,Low tissue specificity,Cell type enhanced,6,MYCN(0.937)|TP53(0.859)|SGK1(0.737)|MYC(0.73)|HSP90AA1(0.729)
NDST2,N-deacetylase and N-sulfotransferase 2,ENSG00000166507,8509,P52849,CellAge,1,TRUE,Ndst2,96.7157,TRUE,Spleen,54.2,54.2,Low tissue specificity,Cell type enhanced,1,HS2ST1(0.82)
NEDD4,NEDD4 E3 ubiquitin protein ligase,ENSG00000069869,4734,P46934,CellAge,1,TRUE,Nedd4,81.3333,TRUE,Cells_Cultured_fibroblasts,33.04,33.04,Tissue enhanced,Cell type enhanced,24,UBC(0.995)|RPS27A(0.992)|PTEN(0.984)|UBB(0.979)|UBA52(0.975)
NEK1,NIMA related kinase 1,ENSG00000137601,4750,Q96PY6,CellAge,1,TRUE,Nek1,77.4495,TRUE,Nerve_Tibial,63.88,63.88,Low tissue specificity,Cell type enhanced,0,
NEK2,NIMA related kinase 2,ENSG00000117650,4751,P51955,CellAge,1,TRUE,Nek2,88.0899,TRUE,Testis,52.47,52.47,Group enriched,Cell type enriched,45,ANAPC4(0.999)|BUB1B(0.999)|CDC27(0.999)|MAD2L1(0.999)|FZR1(0.998)
NEK4,NIMA related kinase 4,ENSG00000114904,6787,P51957,CellAge,1,TRUE,Nek4,72.176,TRUE,Testis,41.4,41.4,Tissue enhanced,Cell type enhanced,0,
NEK6,NIMA related kinase 6,ENSG00000119408,10783,Q9HC98,CellAge,1,TRUE,Nek6,95.2077,TRUE,Cells_EBV-transformed_lymphocytes,138.49,138.49,Tissue enhanced,Cell type enhanced,1,NEK9(0.975)
NEK9,NIMA related kinase 9,ENSG00000119638,91754,Q8TD19,CellAge,1,TRUE,Nek9,95.5056,FALSE,Ovary,75.46,75.46,Low tissue specificity,Cell type enhanced,2,NEK6(0.975)|PLK1(0.856)
NF1,neurofibromin 1,ENSG00000196712,4763,P21359,CellAge,1,TRUE,Nf1,94.1881,TRUE,Cells_Cultured_fibroblasts,17.85,17.85,Low tissue specificity,Low cell type specificity,27,HRAS(0.994)|NRAS(0.994)|NF2(0.97)|RRAS2(0.958)|BRAF(0.903)
NF2,"NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor",ENSG00000186575,4771,P35240,CellAge,1,TRUE,Nf2,98.4874,TRUE,Brain_Cerebellum,30.43,30.43,Low tissue specificity,Cell type enhanced,15,LATS1(0.997)|LATS2(0.996)|NF1(0.97)|CTNNB1(0.889)|YAP1(0.873)
NFE2L1,NFE2 like bZIP transcription factor 1,ENSG00000082641,4779,Q14494,GenAge,1,TRUE,Nfe2l1,93.2643,TRUE,Muscle_Skeletal,612.34,612.34,Tissue enhanced,Cell type enhanced,3,MAF(0.97)|KEAP1(0.937)|PPARGC1A(0.727)
NFE2L2,NFE2 like bZIP transcription factor 2,ENSG00000116044,4780,Q16236,CellAge|GenAge,2,TRUE,Nfe2l2,80.9917,TRUE,Esophagus_Mucosa,174.26,174.26,Low tissue specificity,Cell type enhanced,46,KEAP1(0.999)|MAF(0.998)|NQO1(0.978)|EIF2AK3(0.977)|PARK7(0.969)
NFKB1,nuclear factor kappa B subunit 1,ENSG00000109320,4790,P19838,GenAge|Reactome,2,TRUE,Nfkb1,87.2033,TRUE,Cells_EBV-transformed_lymphocytes,98,98,Low tissue specificity,Cell type enhanced,126,BCL3(0.999)|CHUK(0.999)|IKBKB(0.999)|IKBKG(0.999)|NFKB2(0.999)
NFKB2,nuclear factor kappa B subunit 2,ENSG00000077150,4791,Q00653,CellAge|GenAge,2,TRUE,Nfkb2,91.7778,FALSE,Cells_EBV-transformed_lymphocytes,181.25,181.25,Low tissue specificity,Cell type enhanced,20,BCL3(0.999)|NFKB1(0.999)|RELA(0.999)|RELB(0.999)|CHUK(0.998)
NFKBIA,NFKB inhibitor alpha,ENSG00000100906,4792,P25963,CellAge|GenAge,2,TRUE,Nfkbia,89.9054,FALSE,Lung,497.48,497.48,Tissue enhanced,Cell type enhanced,73,CHUK(0.999)|IKBKB(0.999)|IKBKG(0.999)|NFKB1(0.999)|RELA(0.999)
NGF,nerve growth factor,ENSG00000134259,4803,P01138,GenAge,1,TRUE,Ngf,85.0622,TRUE,Ovary,33.47,33.47,Tissue enhanced,Cell type enhanced,39,NGFR(0.999)|EGFR(0.892)|KDR(0.876)|FGF2(0.869)|STAT3(0.867)
NGFR,nerve growth factor receptor,ENSG00000064300,4804,P08138,GenAge,1,TRUE,Ngfr,91.8033,TRUE,Nerve_Tibial,374.41,374.41,Low tissue specificity,Cell type enhanced,30,BDNF(0.999)|NGF(0.999)|BEX3(0.991)|RTN4(0.977)|RHOA(0.972)
NHEJ1,non-homologous end joining factor 1,ENSG00000187736,79840,Q9H9Q4,CellAge,1,TRUE,Nhej1,73.2441,TRUE,Testis,23.61,23.61,Low tissue specificity,Cell type enhanced,20,PRKDC(0.999)|XRCC5(0.999)|XRCC6(0.999)|ATM(0.982)|ERCC1(0.943)
NINJ1,ninjurin 1,ENSG00000131669,4814,Q92982,CellAge,1,TRUE,Ninj1,89.4737,TRUE,Whole_Blood,187.47,187.47,Tissue enhanced,Cell type enhanced,0,
NIPA2,NIPA magnesium transporter 2,ENSG00000140157,81614,Q8N8Q9,CellAge,1,TRUE,Nipa2,95.5556,TRUE,Cells_EBV-transformed_lymphocytes,96.18,96.18,Low tissue specificity,Cell type enhanced,1,IGFBP2(0.915)
NLK,nemo like kinase,ENSG00000087095,51701,Q9UBE8,CellAge,1,TRUE,Nlk,99.6205,TRUE,Brain_Frontal_Cortex_BA9,53.38,53.38,Tissue enhanced,Cell type enhanced,5,MAP3K7(0.977)|FOXO1(0.964)|FOXO3(0.937)|FOXO4(0.934)|CTNNB1(0.888)
NLRX1,NLR family member X1,ENSG00000160703,79671,Q86UT6,CellAge,1,TRUE,Nlrx1,90.1538,TRUE,Esophagus_Mucosa,48.85,48.85,Tissue enhanced,Cell type enhanced,10,MAVS(0.999)|ATG16L1(0.949)|ATG5(0.905)|ATG12(0.861)|IKBKB(0.845)
NOG,noggin,ENSG00000183691,9241,Q13253,GenAge,1,TRUE,Nog,99.1379,TRUE,Cervix_Ectocervix,8.8,8.8,Tissue enhanced,Group enriched,8,BMP2(0.999)|BMP4(0.999)|BMP6(0.99)|FGF2(0.87)|EGF(0.801)
NOLC1,nucleolar and coiled-body phosphoprotein 1,ENSG00000166197,9221,Q14978,CellAge,1,TRUE,Nolc1,71.6738,TRUE,Cells_EBV-transformed_lymphocytes,138.46,138.46,Low tissue specificity,Low cell type specificity,4,DKC1(0.997)|GAR1(0.915)|CSNK2A1(0.746)|PDCD11(0.738)
NOTCH1,notch receptor 1,ENSG00000148400,4851,P46531,CellAge,1,TRUE,Notch1,90.6458,TRUE,Lung,47.51,47.51,Low tissue specificity,Cell type enhanced,39,RBPJ(0.999)|DLL3(0.998)|PSEN1(0.998)|HIF1A(0.993)|CTNNB1(0.976)
NOTCH3,notch receptor 3,ENSG00000074181,4854,Q9UM47,CellAge,1,TRUE,Notch3,90.9522,TRUE,Artery_Tibial,402.46,402.46,Tissue enhanced,Cell type enhanced,12,DLL3(0.998)|RBPJ(0.998)|NFKB1(0.919)|RELA(0.917)|TACC3(0.908)
NOX1,NADPH oxidase 1,ENSG00000007952,27035,Q9Y5S8,CellAge,1,TRUE,Nox1,84.0426,FALSE,Colon_Transverse,26.51,26.51,Tissue enriched,Group enriched,9,CYBB(0.998)|NOX4(0.998)|AKT1(0.949)|TNFRSF1A(0.919)|DPP4(0.876)
NOX4,NADPH oxidase 4,ENSG00000086991,50507,Q9NPH5,CellAge,1,TRUE,Nox4,90.6574,TRUE,Artery_Aorta,36.8,36.8,Group enriched,Cell type enhanced,7,CYBB(0.998)|NOX1(0.998)|TLR4(0.996)|SMAD3(0.805)|STAT5B(0.793)
NPM1,nucleophosmin 1,ENSG00000181163,4869,P06748,CellAge,1,TRUE,Npm1,94.2177,TRUE,Cells_EBV-transformed_lymphocytes,1517.48,1517.48,Low tissue specificity,Cell type enhanced,72,CDKN2A(0.999)|TP53(0.997)|AGO2(0.992)|HJURP(0.983)|MDM2(0.974)
NQO1,NAD(P)H quinone dehydrogenase 1,ENSG00000181019,1728,P15559,CellAge,1,TRUE,Nqo1,86.4964,TRUE,Cells_Cultured_fibroblasts,295.27,295.27,Tissue enhanced,Cell type enhanced,11,NFE2L2(0.978)|KEAP1(0.953)|GCLM(0.949)|TP53(0.946)|GCLC(0.906)
NR1H2,nuclear receptor subfamily 1 group H member 2,ENSG00000131408,7376,P55055,CellAge,1,TRUE,Nr1h2,86.5217,FALSE,Artery_Tibial,143.92,143.92,Low tissue specificity,Cell type enhanced,7,OGT(0.903)|SREBF1(0.884)|NCOR1(0.876)|NCOR2(0.825)|MED1(0.816)
NR2E1,nuclear receptor subfamily 2 group E member 1,ENSG00000112333,7101,Q9Y466,CellAge,1,TRUE,Nr2e1,98.961,TRUE,Brain_Caudate_basal_ganglia,19.98,19.98,Group enriched,Cell type enriched,4,KDM1A(0.977)|HDAC2(0.799)|HDAC7(0.785)|HDAC1(0.719)
NR3C1,nuclear receptor subfamily 3 group C member 1,ENSG00000113580,2908,P04150,GenAge,1,TRUE,Nr3c1,90.2188,TRUE,Cells_EBV-transformed_lymphocytes,55.25,55.25,Low tissue specificity,Cell type enhanced,47,HSP90AA1(0.999)|HSP90AB1(0.998)|NCOR1(0.995)|PPARGC1A(0.987)|STAT3(0.981)
NRAS,"NRAS proto-oncogene, GTPase",ENSG00000213281,4893,P01111,CellAge,1,TRUE,Nras,99.4709,TRUE,Cells_EBV-transformed_lymphocytes,77.29,77.29,Low tissue specificity,Cell type enhanced,60,BRAF(0.999)|RAF1(0.999)|PIK3CA(0.995)|NF1(0.994)|EGFR(0.991)
NRF1,nuclear respiratory factor 1,ENSG00000106459,4899,Q16656,CellAge,1,TRUE,Nrf1,90.0596,TRUE,Brain_Cerebellar_Hemisphere,25.37,25.37,Low tissue specificity,Cell type enhanced,4,PPARGC1A(0.999)|FOXO3(0.933)|SIRT1(0.826)|SIRT7(0.776)
NRG1,neuregulin 1,ENSG00000157168,3084,Q02297,GenAge|SenMayo,2,TRUE,Nrg1,68.75,TRUE,Cervix_Endocervix,5.05,5.05,Tissue enhanced,Cell type enhanced,10,EGFR(0.999)|ERBB2(0.999)|EGF(0.972)|EREG(0.845)|SRC(0.791)
NRSN2,neurensin 2,ENSG00000125841,80023,Q9GZP1,CellAge,1,TRUE,Nrsn2,57.3529,FALSE,Brain_Frontal_Cortex_BA9,142.92,142.92,Tissue enhanced,Cell type enhanced,0,
NSUN2,NOP2/Sun RNA methyltransferase 2,ENSG00000037474,54888,Q08J23,CellAge,1,TRUE,Nsun2,86.8318,TRUE,Cells_EBV-transformed_lymphocytes,100.58,100.58,Low tissue specificity,Low cell type specificity,7,TRDMT1(0.883)|NPM1(0.867)|AURKB(0.837)|PES1(0.798)|MYC(0.775)
NTN4,netrin 4,ENSG00000074527,59277,Q9HB63,CellAge,1,TRUE,Ntn4,89.8089,TRUE,Spleen,130.59,130.59,Tissue enhanced,Cell type enhanced,0,
NUAK1,NUAK family kinase 1,ENSG00000074590,9891,O60285,CellAge,1,TRUE,Nuak1,90.7716,TRUE,Brain_Frontal_Cortex_BA9,45.4,45.4,Low tissue specificity,Cell type enhanced,2,STK11(0.93)|TP53(0.722)
NUAK2,NUAK family kinase 2,ENSG00000163545,81788,Q9H093,CellAge,1,TRUE,Nuak2,86.6242,TRUE,Vagina,67.04,67.04,Tissue enhanced,Cell type enhanced,0,
NUDT1,nudix hydrolase 1,ENSG00000106268,4521,P36639,GenAge,1,TRUE,Nudt1,82.6923,TRUE,Testis,49.18,49.18,Tissue enhanced,Cell type enhanced,2,OGG1(0.922)|NUDT5(0.767)
NUDT5,nudix hydrolase 5,ENSG00000165609,11164,Q9UKK9,CellAge,1,TRUE,Nudt5,82.1918,TRUE,Cells_Cultured_fibroblasts,39.7,39.7,Low tissue specificity,Cell type enhanced,2,PYCR1(0.848)|NUDT1(0.767)
NUTF2,nuclear transport factor 2,ENSG00000102898,10204,P61970,CellAge,1,TRUE,Nutf2-ps1,100,TRUE,Cells_Cultured_fibroblasts,94.82,94.82,Low tissue specificity,Cell type enhanced,4,RAN(0.999)|RCC1(0.861)|XPO1(0.816)|RAE1(0.704)
OGG1,8-oxoguanine DNA glycosylase,ENSG00000114026,4968,O15527,CellAge,1,TRUE,Ogg1,84.3478,TRUE,Ovary,23.63,23.63,Low tissue specificity,Cell type enhanced,13,APEX1(0.986)|NUDT1(0.922)|POLB(0.89)|XPA(0.87)|APTX(0.865)
OGT,O-linked N-acetylglucosamine (GlcNAc) transferase,ENSG00000147162,8473,O15294,CellAge,1,TRUE,Ogt,99.6176,TRUE,Fallopian_Tube,262.76,262.76,Low tissue specificity,Low cell type specificity,28,MCRS1(0.99)|CSNK2A1(0.982)|BAP1(0.978)|SIN3A(0.96)|GSK3B(0.951)
OPA1,OPA1 mitochondrial dynamin like GTPase,ENSG00000198836,4976,O60313,CellAge,1,TRUE,Opa1,91.133,TRUE,Cells_EBV-transformed_lymphocytes,41.69,41.69,Low tissue specificity,Low cell type specificity,7,FIS1(0.915)|PHB2(0.905)|PINK1(0.855)|SIRT3(0.763)|PRKN(0.757)
ORAI1,ORAI calcium release-activated calcium modulator 1,ENSG00000293604,84876,Q96D31,CellAge,1,FALSE,,,FALSE,,,,,,4,STIM1(0.999)|ITPR3(0.88)|ITPR1(0.878)|ITPR2(0.778)
ORC1,origin recognition complex subunit 1,ENSG00000085840,4998,Q13415,CellAge,1,TRUE,Orc1,66.0859,TRUE,Cells_EBV-transformed_lymphocytes,30.17,30.17,Tissue enhanced,Cell type enhanced,25,CDC6(0.999)|MCM7(0.997)|CDC45(0.99)|CCNA2(0.977)|CDC7(0.93)
OTX2,orthodenticle homeobox 2,ENSG00000165588,5015,P32243,CellAge,1,TRUE,Otx2,99.3266,TRUE,Brain_Cerebellar_Hemisphere,24.43,24.43,Group enriched,Group enriched,5,SOX2(0.914)|POU5F1(0.912)|SIX6(0.894)|SOX1(0.807)|NANOG(0.758)
OXTR,oxytocin receptor,ENSG00000180914,5021,P30559,CellAge,1,TRUE,Oxtr,92.0308,TRUE,Cells_EBV-transformed_lymphocytes,13.74,13.74,Tissue enriched,Cell type enriched,4,EDN1(0.783)|SST(0.77)|ESR1(0.751)|GJA1(0.704)
P2RY14,purinergic receptor P2Y14,ENSG00000174944,9934,Q15391,CellAge,1,TRUE,P2ry14,83.1361,TRUE,Bladder,11.38,11.38,Tissue enhanced,Cell type enhanced,0,
P3H1,prolyl 3-hydroxylase 1,ENSG00000117385,64175,Q32P28,CellAge,1,TRUE,P3h1,88.0435,TRUE,Cells_Cultured_fibroblasts,107,107,Low tissue specificity,Cell type enhanced,1,PPIB(0.999)
PAK2,p21 (RAC1) activated kinase 2,ENSG00000180370,5062,Q13177,CellAge,1,TRUE,Pak2,97.1374,TRUE,Cells_EBV-transformed_lymphocytes,67.94,67.94,Low tissue specificity,Cell type enhanced,7,CDC42(0.998)|RAF1(0.962)|LIMK1(0.944)|MAP2K1(0.925)|MYLK(0.766)
PAK4,p21 (RAC1) activated kinase 4,ENSG00000130669,10298,O96013,CellAge,1,TRUE,Pak4,93.0626,TRUE,Testis,33.08,33.08,Low tissue specificity,Low cell type specificity,5,CDC42(0.999)|LIMK1(0.968)|RAF1(0.949)|MAP2K1(0.928)|PIK3R1(0.8)
PAPPA,pappalysin 1,ENSG00000182752,5069,Q13219,GenAge|SenMayo,2,TRUE,Pappa,91.1494,TRUE,Cells_Cultured_fibroblasts,61.61,61.61,Tissue enriched,Cell type enhanced,6,IGFBP5(0.977)|IGFBP4(0.976)|IGF1(0.89)|PGF(0.799)|IGF2(0.756)
PAPSS2,3'-phosphoadenosine 5'-phosphosulfate synthase 2,ENSG00000198682,9060,O95340,CellAge,1,TRUE,Papss2,92.4071,TRUE,Adrenal_Gland,195.46,195.46,Tissue enhanced,Cell type enhanced,1,EEF1A1(0.914)
PARK7,Parkinsonism associated deglycase,ENSG00000116288,11315,Q99497,CellAge,1,TRUE,Park7,91.5344,TRUE,Cells_EBV-transformed_lymphocytes,303.72,303.72,Low tissue specificity,Cell type enhanced,28,PINK1(0.999)|PRKN(0.999)|SOD1(0.997)|HSPA9(0.992)|MAP3K5(0.991)
PARP1,poly(ADP-ribose) polymerase 1,ENSG00000143799,142,P09874,CellAge|GenAge,2,TRUE,Parp1,92.5049,TRUE,Cells_EBV-transformed_lymphocytes,173.97,173.97,Low tissue specificity,Cell type enhanced,93,XRCC6(0.998)|POLB(0.996)|SMARCA4(0.996)|XRCC5(0.996)|PRKDC(0.993)
PATZ1,POZ/BTB and AT hook containing zinc finger 1,ENSG00000100105,23598,Q9HBE1,CellAge,1,TRUE,Patz1,98.9811,TRUE,Thyroid,39.11,39.11,Low tissue specificity,Low cell type specificity,3,EWSR1(0.88)|TP53(0.764)|NCOR1(0.726)
PAX8,paired box 8,ENSG00000125618,7849,Q06710,CellAge,1,TRUE,Pax8,98.2222,TRUE,Thyroid,1192.66,1192.66,Group enriched,Cell type enhanced,10,PPARG(0.994)|PRKCA(0.911)|SMAD3(0.839)|NRAS(0.803)|WT1(0.781)
PBRM1,polybromo 1,ENSG00000163939,55193,Q86U86,CellAge,1,TRUE,Pbrm1,98.1807,TRUE,Ovary,28.07,28.07,Low tissue specificity,Low cell type specificity,21,ARID1A(0.999)|BRD7(0.999)|SMARCA2(0.999)|SMARCA4(0.999)|SMARCB1(0.999)
PCGF2,polycomb group ring finger 2,ENSG00000277258,7703,P35227,CellAge,1,TRUE,Pcgf2,95.3488,FALSE,Cervix_Endocervix,85.13,85.13,Low tissue specificity,Cell type enhanced,44,BMI1(0.999)|CBX2(0.999)|PHC1(0.999)|RING1(0.999)|RNF2(0.999)
PCK1,phosphoenolpyruvate carboxykinase 1,ENSG00000124253,5105,P35558,GenAge,1,TRUE,Pck1,90.836,TRUE,Liver,529.98,529.98,Tissue enhanced,Group enriched,8,ENO1(0.962)|ACLY(0.959)|PPARG(0.907)|PPARGC1A(0.84)|FOXO1(0.812)
PCMT1,protein-L-isoaspartate (D-aspartate) O-methyltransferase,ENSG00000120265,5110,P22061,GenAge,1,TRUE,Pcmt1,94.7137,TRUE,Brain_Frontal_Cortex_BA9,151.51,151.51,Low tissue specificity,Cell type enhanced,0,
PCNA,proliferating cell nuclear antigen,ENSG00000132646,5111,P12004,GenAge,1,TRUE,Pcna,96.9349,TRUE,Cells_EBV-transformed_lymphocytes,459.51,459.51,Tissue enhanced,Cell type enhanced,61,CDKN1A(0.999)|FEN1(0.999)|POLD1(0.999)|CDK4(0.996)|DTL(0.995)
PDCD10,programmed cell death 10,ENSG00000114209,11235,Q9BUL8,CellAge,1,TRUE,Pdcd10,91.9811,TRUE,Cells_EBV-transformed_lymphocytes,60.65,60.65,Low tissue specificity,Cell type enhanced,2,PPP2R1A(0.998)|RHOA(0.729)
PDCD11,programmed cell death 11,ENSG00000148843,22984,Q14690,CellAge,1,TRUE,Pdcd11,80.1176,TRUE,Cells_EBV-transformed_lymphocytes,52.18,52.18,Low tissue specificity,Low cell type specificity,16,BMS1(0.999)|RPL11(0.998)|RPS9(0.997)|RPS14(0.995)|UTP6(0.994)
PDCD4,programmed cell death 4,ENSG00000150593,27250,Q53EL6,CellAge,1,TRUE,Pdcd4,96.8017,TRUE,Pancreas,284.41,284.41,Tissue enhanced,Cell type enhanced,8,RPS6KB1(0.82)|AGO2(0.814)|PTEN(0.805)|EIF4E(0.802)|RECK(0.793)
PDGFB,platelet derived growth factor subunit B,ENSG00000100311,5155,P01127,CellAge|GenAge,2,TRUE,Pdgfb,89.6266,TRUE,Adipose_Subcutaneous,49.14,49.14,Low tissue specificity,Cell type enhanced,24,PDGFRA(0.999)|PDGFRB(0.999)|EGFR(0.968)|EGF(0.955)|FGF2(0.953)
PDGFRA,platelet derived growth factor receptor alpha,ENSG00000134853,5156,P16234,GenAge,1,TRUE,Pdgfra,91.8274,TRUE,Ovary,217.53,217.53,Tissue enhanced,Group enriched,62,PDGFB(0.999)|PIK3R1(0.995)|PTPN11(0.995)|PIK3CA(0.99)|PDGFRB(0.989)
PDGFRB,platelet derived growth factor receptor beta,ENSG00000113721,5159,P09619,GenAge,1,TRUE,Pdgfrb,84.8101,TRUE,Cervix_Ectocervix,398.15,398.15,Low tissue specificity,Cell type enhanced,63,GRB2(0.999)|PDGFB(0.999)|PIK3R1(0.999)|PTPN11(0.999)|SRC(0.999)
PDIK1L,PDLIM1 interacting kinase 1 like,ENSG00000175087,149420,Q8N165,CellAge,1,TRUE,Pdik1l,99.4135,TRUE,Brain_Cerebellar_Hemisphere,12.17,12.17,Low tissue specificity,Cell type enhanced,2,ATG5(0.721)|ATG12(0.703)
PDPK1,3-phosphoinositide dependent protein kinase 1,ENSG00000140992,5170,O15530,CellAge|GenAge,2,TRUE,Pdpk1,95.3237,TRUE,Brain_Cerebellar_Hemisphere,34.44,34.44,Low tissue specificity,Cell type enhanced,23,AKT1(0.999)|SGK1(0.988)|RPS6KB1(0.986)|PIK3CA(0.976)|PIK3CB(0.973)
PDZD2,PDZ domain containing 2,ENSG00000133401,23037,O15018,CellAge,1,TRUE,Pdzd2,68.6862,TRUE,Nerve_Tibial,38.37,38.37,Tissue enhanced,Cell type enhanced,0,
PEA15,proliferation and apoptosis adaptor protein 15,ENSG00000162734,8682,Q15121,CellAge,1,TRUE,Pea15a,99.2308,TRUE,Brain_Spinal_cord_cervical_c-1,2208.6,2208.6,Tissue enriched,Cell type enhanced,3,MAPK1(0.998)|MAPK3(0.961)|RPS6KA3(0.859)
PEBP1,phosphatidylethanolamine binding protein 1,ENSG00000089220,5037,P30086,CellAge,1,TRUE,Pbp2,84.492,FALSE,Adrenal_Gland,2476.26,2476.26,Tissue enhanced,Cell type enhanced,6,RAF1(0.988)|BRAF(0.851)|MAP2K1(0.805)|YWHAB(0.756)|PRDX1(0.729)
PECAM1,platelet and endothelial cell adhesion molecule 1,ENSG00000261371,5175,P16284,SenMayo,1,TRUE,Pecam1,63.4146,TRUE,Lung,313.44,313.44,Tissue enhanced,Cell type enhanced,32,KDR(0.999)|PTPN11(0.999)|CTNNB1(0.998)|PTPN6(0.979)|SRC(0.948)
PELP1,"proline, glutamate and leucine rich protein 1",ENSG00000141456,27043,Q8IZL8,CellAge,1,TRUE,Pelp1,86.4602,FALSE,Testis,63.51,63.51,Low tissue specificity,Low cell type specificity,13,ESR1(0.95)|RUVBL2(0.922)|TAF1(0.909)|MAX(0.903)|RNF2(0.902)
PES1,pescadillo ribosomal biogenesis factor 1,ENSG00000100029,23481,O00541,CellAge,1,TRUE,Pes1,78.2313,TRUE,Cells_Cultured_fibroblasts,91.43,91.43,Low tissue specificity,Low cell type specificity,11,PDCD11(0.969)|DKC1(0.959)|MYBBP1A(0.948)|BMS1(0.947)|RPL11(0.941)
PEX19,peroxisomal biogenesis factor 19,ENSG00000162735,5824,P40855,CellAge,1,TRUE,Pex19,89.9666,TRUE,Adipose_Subcutaneous,67.36,67.36,Low tissue specificity,Cell type enhanced,2,PEX5(0.959)|FIS1(0.848)
PEX5,peroxisomal biogenesis factor 5,ENSG00000288217,5830,P50542,GenAge,1,FALSE,,,FALSE,,,,,,7,ATM(0.964)|PEX19(0.959)|NBR1(0.957)|SQSTM1(0.943)|CAT(0.794)
PGF,placental growth factor,ENSG00000119630,5228,P49763,SenMayo,1,TRUE,Pgf,59.4118,TRUE,Thyroid,90.73,90.73,Tissue enhanced,Group enriched,21,FLT1(0.999)|KDR(0.999)|PDGFRB(0.905)|ENG(0.886)|SPP1(0.85)
PGR,progesterone receptor,ENSG00000082175,5241,P06401,CellAge,1,TRUE,Pgr,79.9571,TRUE,Cervix_Endocervix,111.01,111.01,Group enriched,Cell type enhanced,38,NCOR1(0.993)|NCOR2(0.992)|HSP90AA1(0.99)|ERBB2(0.98)|HSP90AB1(0.978)
PHB1,prohibitin 1,ENSG00000167085,5245,P35232,CellAge,1,TRUE,Phb1,99.6324,TRUE,Cells_EBV-transformed_lymphocytes,267.8,267.8,Low tissue specificity,Cell type enhanced,0,
PHB2,prohibitin 2,ENSG00000215021,11331,Q99623,CellAge,1,TRUE,Phb2,100,TRUE,Cells_EBV-transformed_lymphocytes,430.31,430.31,Low tissue specificity,Cell type enhanced,12,PHB(0.999)|ESR1(0.985)|HDAC1(0.946)|OPA1(0.905)|HSPA9(0.882)
PHC1,polyhomeotic homolog 1,ENSG00000111752,1911,P78364,Reactome,1,TRUE,Phc1,92.4303,FALSE,Pituitary,51.57,51.57,Low tissue specificity,Low cell type specificity,40,BMI1(0.999)|CBX2(0.999)|PCGF2(0.999)|RING1(0.999)|RNF2(0.999)
PHC2,polyhomeotic homolog 2,ENSG00000134686,1912,Q8IXK0,Reactome,1,TRUE,Phc2,83.1199,FALSE,Whole_Blood,253.04,253.04,Low tissue specificity,Cell type enhanced,40,BMI1(0.999)|CBX2(0.999)|CBX8(0.999)|PCGF2(0.998)|RING1(0.998)
PHC3,polyhomeotic homolog 3,ENSG00000173889,80012,Q8NDX5,Reactome,1,TRUE,Phc3,92.3618,TRUE,Cells_EBV-transformed_lymphocytes,16.15,16.15,Tissue enhanced,Cell type enhanced,40,CBX8(0.998)|CBX2(0.996)|PHC1(0.996)|CBX4(0.995)|RNF2(0.994)
PHGDH,phosphoglycerate dehydrogenase,ENSG00000092621,26227,O43175,CellAge,1,TRUE,Phgdh,94.5591,TRUE,Cells_Cultured_fibroblasts,83.08,83.08,Low tissue specificity,Cell type enhanced,6,GAPDH(0.891)|TYMS(0.838)|XPO1(0.786)|MYC(0.782)|MTHFD2(0.722)
PI4KB,phosphatidylinositol 4-kinase beta,ENSG00000143393,5298,Q9UBF8,CellAge,1,TRUE,Pi4kb,96.6912,TRUE,Nerve_Tibial,100.62,100.62,Low tissue specificity,Low cell type specificity,5,ARF1(0.981)|PIK3R1(0.925)|PTEN(0.914)|PIK3C2A(0.912)|YWHAB(0.766)
PIGF,phosphatidylinositol glycan anchor biosynthesis class F,ENSG00000151665,5281,Q07326,SenMayo,1,TRUE,Pigf,86.3014,TRUE,Cells_Cultured_fibroblasts,10.96,10.96,Low tissue specificity,Cell type enhanced,0,
PIK3C2A,phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha,ENSG00000011405,5286,O00443,CellAge,1,TRUE,Pik3c2a,90.2135,TRUE,Uterus,35.28,35.28,Low tissue specificity,Cell type enhanced,7,PIK3R1(0.938)|PTEN(0.934)|INPP4B(0.932)|PI4KB(0.912)|PIK3CB(0.777)
PIK3CA,"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha",ENSG00000121879,5290,P42336,CellAge|GenAge,2,TRUE,Pik3ca,98.6891,TRUE,Artery_Tibial,23.19,23.19,Low tissue specificity,Cell type enhanced,82,EGFR(0.999)|IRS1(0.999)|PIK3R1(0.999)|PIK3R5(0.999)|AKT1(0.998)
PIK3CB,"phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta",ENSG00000051382,5291,P42338,GenAge,1,TRUE,Pik3cb,95.3271,TRUE,Brain_Cerebellar_Hemisphere,28.01,28.01,Low tissue specificity,Cell type enhanced,53,CDC42(0.999)|PIK3R1(0.999)|PIK3R5(0.999)|PIK3CA(0.998)|EGFR(0.993)
PIK3R1,phosphoinositide-3-kinase regulatory subunit 1,ENSG00000145675,5295,P27986,GenAge,1,TRUE,Pik3r1,95.9945,TRUE,Nerve_Tibial,154.42,154.42,Low tissue specificity,Cell type enhanced,76,IRS1(0.999)|PDGFRB(0.999)|PIK3CA(0.999)|PIK3CB(0.999)|EGFR(0.998)
PIK3R5,phosphoinositide-3-kinase regulatory subunit 5,ENSG00000141506,23533,Q8WYR1,CellAge,1,TRUE,Pik3r5,86.0227,TRUE,Whole_Blood,59.93,59.93,Tissue enhanced,Cell type enhanced,15,PIK3CA(0.999)|PIK3CB(0.999)|PIK3R1(0.966)|AKT1(0.945)|AKT3(0.941)
PIM1,"Pim-1 proto-oncogene, serine/threonine kinase",ENSG00000137193,5292,P11309,CellAge,1,TRUE,Pim1,94.2492,TRUE,Esophagus_Mucosa,240.02,240.02,Tissue enhanced,Cell type enriched,4,STAT5A(0.833)|STAT5B(0.821)|MYC(0.796)|STAT3(0.733)
PIN1,"peptidylprolyl cis/trans isomerase, NIMA-interacting 1",ENSG00000127445,5300,Q13526,CellAge|GenAge,2,TRUE,Pin1,95.092,TRUE,Brain_Frontal_Cortex_BA9,132.62,132.62,Tissue enhanced,Cell type enhanced,10,IRF3(0.967)|HIPK2(0.965)|TP53(0.946)|SFN(0.909)|MYC(0.881)
PINK1,PTEN induced kinase 1,ENSG00000158828,65018,Q9BXM7,CellAge,1,TRUE,Pink1,81.4114,TRUE,Muscle_Skeletal,84.29,84.29,Tissue enhanced,Cell type enhanced,33,PARK7(0.999)|PRKN(0.999)|BECN1(0.996)|HTRA2(0.994)|UBC(0.989)
PINX1,PIN2 (TERF1) interacting telomerase inhibitor 1,ENSG00000284764,54984,Q96BK5,CellAge,1,FALSE,,,FALSE,,,,,,2,TERF1(0.953)|TERT(0.739)
PIR,pirin,ENSG00000087842,8544,O00625,CellAge,1,TRUE,Pir,95.5172,TRUE,Bladder,29.74,29.74,Low tissue specificity,Cell type enhanced,2,BCL3(0.983)|CTF1(0.91)
PITX1,paired like homeodomain 1,ENSG00000069011,5307,P78337,CellAge,1,TRUE,Pitx1,96.8153,TRUE,Esophagus_Mucosa,816.39,816.39,Tissue enhanced,Cell type enhanced,2,EGR1(0.856)|POU1F1(0.845)
PLA2G2A,phospholipase A2 group IIA,ENSG00000188257,5320,P14555,CellAge,1,TRUE,Pla2g2a,31.9444,FALSE,Artery_Coronary,903.55,903.55,Tissue enhanced,Cell type enriched,5,PLA2R1(0.93)|PTGS2(0.924)|ALOX15B(0.747)|MAPK3(0.738)|PLD2(0.707)
PLA2R1,phospholipase A2 receptor 1,ENSG00000153246,22925,Q13018,CellAge,1,TRUE,Pla2r1,73.6842,TRUE,Thyroid,46.92,46.92,Tissue enhanced,Cell type enriched,1,PLA2G2A(0.93)
PLAT,"plasminogen activator, tissue type",ENSG00000104368,5327,P00750,SenMayo,1,TRUE,Plat,79.8932,TRUE,Nerve_Tibial,102.93,102.93,Tissue enhanced,Cell type enhanced,14,SERPINE1(0.999)|SERPINB2(0.989)|MMP9(0.893)|SERPINE2(0.878)|PLAUR(0.851)
PLAU,"plasminogen activator, urokinase",ENSG00000122861,5328,P00749,GenAge|SenMayo,2,TRUE,Plau,69.3736,TRUE,Kidney_Medulla,117.94,117.94,Tissue enhanced,Group enriched,23,PLAUR(0.999)|SERPINE1(0.999)|SERPINB2(0.986)|SERPINE2(0.946)|CTSB(0.88)
PLAUR,"plasminogen activator, urokinase receptor",ENSG00000011422,5329,Q03405,SenMayo,1,TRUE,Plaur,61.194,FALSE,Whole_Blood,86.66,86.66,Tissue enriched,Cell type enhanced,11,PLAU(0.999)|SERPINE1(0.994)|SERPINB2(0.938)|EGFR(0.896)|PLAT(0.851)
PLCG2,phospholipase C gamma 2,ENSG00000197943,5336,P16885,GenAge,1,TRUE,Plcg2,94.1502,TRUE,Cells_EBV-transformed_lymphocytes,95.9,95.9,Tissue enhanced,Cell type enhanced,32,SYK(0.999)|EGFR(0.993)|ERBB2(0.979)|PIK3R1(0.979)|SRC(0.975)
PLD2,phospholipase D2,ENSG00000129219,5338,O14939,CellAge,1,TRUE,Pld2,89.925,TRUE,Esophagus_Mucosa,94.11,94.11,Tissue enhanced,Cell type enhanced,11,ARF1(0.991)|PRKCA(0.952)|RHOA(0.94)|SPHK1(0.932)|RRAS2(0.908)
PLK1,polo like kinase 1,ENSG00000166851,5347,P53350,CellAge,1,TRUE,Plk1,94.5274,FALSE,Cells_EBV-transformed_lymphocytes,102.94,102.94,Tissue enhanced,Cell type enhanced,88,BUB1B(0.999)|CCNB1(0.999)|FZR1(0.999)|AURKA(0.997)|BRCA2(0.996)
PMCH,pro-melanin concentrating hormone,ENSG00000183395,5367,P20382,GenAge,1,TRUE,Pmch,86.6667,TRUE,Brain_Hypothalamus,42.92,42.92,Tissue enriched,Cell type enriched,3,LEP(0.769)|MECP2(0.75)|SST(0.728)
PML,PML nuclear body scaffold,ENSG00000140464,5371,P29590,CellAge|GenAge,2,TRUE,Pml,68.9342,FALSE,Adipose_Subcutaneous,55.29,55.29,Low tissue specificity,Low cell type specificity,33,SUMO1(0.999)|UBE2I(0.981)|RUNX1(0.974)|TP53(0.967)|SPI1(0.938)
PMVK,phosphomevalonate kinase,ENSG00000163344,10654,Q15126,CellAge,1,TRUE,Pmvk,83.3333,TRUE,Pituitary,111.84,111.84,Low tissue specificity,Cell type enhanced,6,MVK(0.994)|HMGCR(0.913)|FDPS(0.901)|SREBF1(0.784)|HMGA1(0.763)
PNPT1,polyribonucleotide nucleotidyltransferase 1,ENSG00000138035,87178,Q8TCS8,CellAge,1,TRUE,Pnpt1,91.1877,FALSE,Cells_EBV-transformed_lymphocytes,39.7,39.7,Low tissue specificity,Low cell type specificity,6,RPL11(0.785)|GRSF1(0.783)|RPS9(0.757)|PDCD11(0.745)|ENO1(0.716)
POLA1,"DNA polymerase alpha 1, catalytic subunit",ENSG00000101868,5422,P09884,GenAge,1,TRUE,Pola1,88.0109,TRUE,Cells_EBV-transformed_lymphocytes,21.07,21.07,Low tissue specificity,Cell type enhanced,23,POLD1(0.989)|PCNA(0.987)|RPA1(0.979)|STN1(0.978)|CDC45(0.964)
POLB,DNA polymerase beta,ENSG00000070501,5423,P06746,GenAge,1,TRUE,Polb,96.4179,TRUE,Brain_Cerebellar_Hemisphere,157.74,157.74,Tissue enhanced,Cell type enhanced,14,APEX1(0.998)|PARP1(0.996)|FEN1(0.987)|APTX(0.9)|OGG1(0.89)
POLD1,"DNA polymerase delta 1, catalytic subunit",ENSG00000062822,5424,P28340,GenAge,1,TRUE,Pold1,89.5212,TRUE,Cells_EBV-transformed_lymphocytes,59.13,59.13,Low tissue specificity,Cell type enhanced,45,PCNA(0.999)|FEN1(0.997)|POLA1(0.989)|RPA1(0.989)|ERCC5(0.966)
POLG,"DNA polymerase gamma, catalytic subunit",ENSG00000140521,5428,P54098,GenAge,1,TRUE,Polg,86.36,TRUE,Nerve_Tibial,48.25,48.25,Low tissue specificity,Low cell type specificity,4,POLD1(0.966)|RRM2B(0.943)|POLA1(0.929)|SPAG9(0.749)
PON1,paraoxonase 1,ENSG00000005421,5444,P27169,CellAge|GenAge,2,TRUE,Pon1,82.2535,TRUE,Liver,137.43,137.43,Tissue enriched,Cell type enriched,6,CLU(0.996)|APOE(0.977)|CETP(0.968)|APOC3(0.933)|APP(0.782)
POT1,protection of telomeres 1,ENSG00000128513,25913,Q9NUX5,CellAge|Reactome,2,TRUE,Pot1a,75.7098,TRUE,Cells_EBV-transformed_lymphocytes,22.67,22.67,Low tissue specificity,Cell type enhanced,17,ACD(0.999)|TERF1(0.999)|TERF2(0.999)|TERF2IP(0.999)|TINF2(0.999)
POU1F1,POU class 1 homeobox 1,ENSG00000064835,5449,P28069,GenAge,1,TRUE,Pou1f1,95.5326,TRUE,Pituitary,111.26,111.26,Tissue enriched,Group enriched,7,PROP1(0.972)|HESX1(0.95)|GHRHR(0.884)|PITX1(0.845)|CREBBP(0.78)
POU3F1,POU class 3 homeobox 1,ENSG00000185668,5453,Q03052,CellAge,1,TRUE,Pou3f1,98.6696,TRUE,Nerve_Tibial,34.03,34.03,Group enriched,Cell type enhanced,1,EGR2(0.876)
POU5F1,POU class 5 homeobox 1,ENSG00000233911,5460,Q01860,CellAge,1,FALSE,,,FALSE,,,,,,48,CTNNB1(0.999)|NANOG(0.999)|SOX2(0.999)|KLF4(0.994)|SMAD3(0.962)
PPARA,peroxisome proliferator activated receptor alpha,ENSG00000186951,5465,Q07869,GenAge,1,TRUE,Ppara,92.3077,TRUE,Liver,21.64,21.64,Tissue enhanced,Cell type enhanced,33,PPARGC1A(0.999)|NCOR2(0.996)|NCOR1(0.991)|JUN(0.979)|UCP1(0.919)
PPARG,peroxisome proliferator activated receptor gamma,ENSG00000132170,5468,P37231,CellAge|GenAge,2,TRUE,Pparg,98.3158,FALSE,Adipose_Subcutaneous,111.14,111.14,Tissue enhanced,Cell type enhanced,83,MED1(0.999)|NCOR1(0.999)|NCOR2(0.999)|PPARGC1A(0.999)|CREBBP(0.998)
PPARGC1A,PPARG coactivator 1 alpha,ENSG00000109819,10891,Q9UBK2,CellAge|GenAge,2,TRUE,Ppargc1a,94.3609,TRUE,Thyroid,17.26,17.26,Tissue enhanced,Cell type enhanced,56,FOXO1(0.999)|NRF1(0.999)|PPARA(0.999)|PPARG(0.999)|SIRT1(0.999)
PPIB,peptidylprolyl isomerase B,ENSG00000166794,5479,P23284,CellAge,1,TRUE,Ppib,93.9815,TRUE,Cells_Cultured_fibroblasts,1305.59,1305.59,Low tissue specificity,Cell type enhanced,4,P3H1(0.999)|CALR(0.987)|HSPA5(0.955)|HYOU1(0.93)
PPM1B,"protein phosphatase, Mg2+/Mn2+ dependent 1B",ENSG00000138032,5495,O75688,CellAge,1,TRUE,Ppm1b,91.2317,TRUE,Brain_Cerebellar_Hemisphere,56.1,56.1,Low tissue specificity,Cell type enhanced,3,MAP3K7(0.946)|CHUK(0.831)|YEATS4(0.751)
PPM1D,"protein phosphatase, Mg2+/Mn2+ dependent 1D",ENSG00000170836,8493,O15297,CellAge|GenAge,2,TRUE,Ppm1d,88.4297,TRUE,Brain_Cerebellar_Hemisphere,24.89,24.89,Low tissue specificity,Low cell type specificity,7,ATM(0.924)|CHEK2(0.918)|TP53(0.883)|MDM2(0.858)|H2AX(0.797)
PPP1CA,protein phosphatase 1 catalytic subunit alpha,ENSG00000172531,5499,P62136,GenAge,1,TRUE,Ppp1ca,99.697,TRUE,Cells_EBV-transformed_lymphocytes,234.27,234.27,Low tissue specificity,Cell type enhanced,18,RB1(0.984)|TP53BP2(0.984)|YAP1(0.959)|PPP1R13B(0.938)|RASSF5(0.915)
PPP1R13B,protein phosphatase 1 regulatory subunit 13B,ENSG00000088808,23368,Q96KQ4,CellAge,1,TRUE,Ppp1r13b,91.7431,TRUE,Thyroid,70.84,70.84,Low tissue specificity,Low cell type specificity,4,TP53(0.986)|PPP1CA(0.938)|TP73(0.728)|TP53BP2(0.726)
PPP2R1A,protein phosphatase 2 scaffold subunit Aalpha,ENSG00000105568,5518,P30153,CellAge,1,FALSE,,,FALSE,Brain_Cerebellum,181.19,181.19,Low tissue specificity,Cell type enhanced,32,PPP2R5A(0.999)|PDCD10(0.998)|MAP2K1(0.95)|TP53(0.946)|RELA(0.933)
PPP2R5A,protein phosphatase 2 regulatory subunit B'alpha,ENSG00000066027,5525,Q15172,CellAge,1,TRUE,Ppp2r5a,97.7366,TRUE,Adipose_Subcutaneous,77.45,77.45,Low tissue specificity,Cell type enhanced,8,PPP2R1A(0.999)|BUB1B(0.98)|BCL2(0.964)|ARRB1(0.807)|AKT1(0.795)
PRDX1,peroxiredoxin 1,ENSG00000117450,5052,Q06830,GenAge,1,TRUE,Prdx1,95.4774,TRUE,Esophagus_Mucosa,790.6,790.6,Low tissue specificity,Cell type enhanced,21,TXN(0.99)|ABL1(0.927)|NFE2L2(0.894)|MAP3K5(0.89)|SOD1(0.876)
PRKAA2,protein kinase AMP-activated catalytic subunit alpha 2,ENSG00000162409,5563,P54646,CellAge,1,TRUE,Prkaa2,97.8261,TRUE,Muscle_Skeletal,26.09,26.09,Tissue enhanced,Cell type enhanced,11,STK11(0.978)|MTOR(0.973)|RPTOR(0.973)|PPARGC1A(0.964)|FOXO3(0.937)
PRKCA,protein kinase C alpha,ENSG00000154229,5578,P17252,GenAge,1,TRUE,Prkca,99.4048,TRUE,Nerve_Tibial,44.71,44.71,Tissue enhanced,Cell type enhanced,50,RACK1(0.97)|MTOR(0.969)|PRKCD(0.967)|MAPK3(0.956)|PLD2(0.952)
PRKCD,protein kinase C delta,ENSG00000163932,5580,Q05655,CellAge|GenAge,2,TRUE,Prkcd,90.3846,TRUE,Whole_Blood,133.75,133.75,Low tissue specificity,Cell type enhanced,29,SRC(0.983)|PRKCA(0.967)|PIK3CB(0.966)|IRS1(0.962)|MARCKS(0.952)
PRKCH,protein kinase C eta,ENSG00000027075,5583,P24723,CellAge,1,TRUE,Prkch,97.6574,TRUE,Lung,30.84,30.84,Low tissue specificity,Cell type enhanced,0,
PRKD1,protein kinase D1,ENSG00000184304,5587,Q15139,CellAge,1,TRUE,Prkd1,93.3114,TRUE,Cells_Cultured_fibroblasts,45.78,45.78,Low tissue specificity,Cell type enhanced,6,PRKD2(0.979)|PRKCA(0.917)|ARF1(0.836)|CREB1(0.769)|HSPB1(0.731)
PRKD2,protein kinase D2,ENSG00000105287,25865,Q9BZL6,CellAge,1,TRUE,Prkd2,95.2164,TRUE,Spleen,79.03,79.03,Low tissue specificity,Cell type enhanced,5,PRKD1(0.979)|PRKCA(0.911)|ARF1(0.836)|ATF2(0.758)|CREB1(0.738)
PRKDC,"protein kinase, DNA-activated, catalytic subunit",ENSG00000253729,5591,P78527,CellAge|GenAge,2,TRUE,Prkdc,79.1182,TRUE,Cells_Cultured_fibroblasts,81.62,81.62,Low tissue specificity,Cell type enhanced,60,NHEJ1(0.999)|XRCC5(0.999)|XRCC6(0.999)|TP53(0.997)|PARP1(0.993)
PRKN,parkin RBR E3 ubiquitin protein ligase,ENSG00000185345,5071,O60260,CellAge,1,TRUE,Prkn,83.6559,TRUE,Muscle_Skeletal,8.7,8.7,Tissue enhanced,Cell type enhanced,46,PARK7(0.999)|PINK1(0.999)|UBC(0.999)|UBA52(0.998)|UBB(0.998)
PRMT1,protein arginine methyltransferase 1,ENSG00000126457,3276,Q99873,CellAge,1,TRUE,Prmt1,87.8706,TRUE,Cells_EBV-transformed_lymphocytes,216.29,216.29,Low tissue specificity,Cell type enhanced,26,EP300(0.994)|BTG2(0.992)|CARM1(0.982)|RUNX1(0.96)|FOXO1(0.939)
PRMT6,protein arginine methyltransferase 6,ENSG00000198890,55170,Q96LA8,CellAge,1,TRUE,Prmt6,92.2667,TRUE,Cells_EBV-transformed_lymphocytes,27.25,27.25,Low tissue specificity,Low cell type specificity,9,HDAC1(0.869)|MECP2(0.844)|SETD1A(0.8)|HMGA1(0.797)|POLB(0.779)
PRODH,proline dehydrogenase 1,ENSG00000100033,5625,O43272,CellAge,1,TRUE,Prodh,81.6667,TRUE,Nerve_Tibial,62.69,62.69,Tissue enhanced,Group enriched,3,PYCR1(0.976)|MT-CO1(0.735)|APEX1(0.72)
PROP1,PROP paired-like homeobox 1,ENSG00000175325,5626,O75360,GenAge,1,TRUE,Prop1,72.5664,FALSE,Pituitary,2.02,2.02,Tissue enriched,Not detected,6,POU1F1(0.972)|GHRHR(0.927)|CTNNB1(0.838)|GHRH(0.82)|GHR(0.756)
PROX1,prospero homeobox 1,ENSG00000117707,5629,Q92786,CellAge,1,TRUE,Prox1,98.3718,TRUE,Liver,30.45,30.45,Tissue enriched,Cell type enhanced,2,VEGFC(0.821)|EP300(0.703)
PRPF19,pre-mRNA processing factor 19,ENSG00000110107,27339,Q9UMS4,CellAge,1,TRUE,Prpf19,99.4048,TRUE,Brain_Cerebellar_Hemisphere,189.85,189.85,Low tissue specificity,Cell type enhanced,13,PTPN11(0.987)|HSPA8(0.968)|MAGOHB(0.945)|HNRNPA1(0.868)|DHX9(0.852)
PSEN1,presenilin 1,ENSG00000080815,5663,P49768,GenAge,1,TRUE,Psen1,92.7195,TRUE,Brain_Spinal_cord_cervical_c-1,39.25,39.25,Low tissue specificity,Cell type enhanced,20,APP(0.999)|CTNNB1(0.999)|NOTCH1(0.998)|GSK3B(0.995)|CDH1(0.98)
PSMA2,proteasome 20S subunit alpha 2,ENSG00000106588,5683,P25787,CellAge,1,TRUE,Psma2,99.5726,TRUE,Cells_EBV-transformed_lymphocytes,121.79,121.79,Low tissue specificity,Cell type enhanced,16,PSMA5(0.999)|PSMB1(0.999)|PSMB5(0.999)|PSMD14(0.999)|RPS27A(0.975)
PSMA5,proteasome 20S subunit alpha 5,ENSG00000143106,5686,P28066,CellAge,1,TRUE,Psma5,100,TRUE,Cells_EBV-transformed_lymphocytes,61.07,61.07,Low tissue specificity,Low cell type specificity,14,PSMA2(0.999)|PSMB1(0.999)|PSMB5(0.999)|PSMD14(0.999)|RPS27A(0.962)
PSMB1,proteasome 20S subunit beta 1,ENSG00000008018,5689,P20618,CellAge,1,TRUE,Psmb1,92.9461,TRUE,Cells_EBV-transformed_lymphocytes,184.06,184.06,Low tissue specificity,Cell type enhanced,11,PSMA2(0.999)|PSMA5(0.999)|PSMB5(0.999)|PSMD14(0.999)|RPS27A(0.969)
PSMB5,proteasome 20S subunit beta 5,ENSG00000100804,5693,P28074,CellAge,1,TRUE,Psmb5,92.7757,TRUE,Cells_Cultured_fibroblasts,196.45,196.45,Low tissue specificity,Cell type enhanced,10,PSMA2(0.999)|PSMA5(0.999)|PSMB1(0.999)|PSMD14(0.998)|RPS27A(0.943)
PSMD14,"proteasome 26S subunit, non-ATPase 14",ENSG00000115233,10213,O00487,CellAge,1,TRUE,Psmd14,100,TRUE,Cells_EBV-transformed_lymphocytes,127.64,127.64,Low tissue specificity,Low cell type specificity,21,PSMA2(0.999)|PSMA5(0.999)|PSMB1(0.999)|PSMB5(0.998)|UBC(0.997)
PTBP1,polypyrimidine tract binding protein 1,ENSG00000011304,5725,P26599,SenMayo,1,TRUE,Ptbp1,96.7684,TRUE,Cells_EBV-transformed_lymphocytes,235.6,235.6,Low tissue specificity,Low cell type specificity,17,HNRNPA1(0.998)|HNRNPC(0.996)|SRSF1(0.983)|ELAVL1(0.974)|HNRNPA3(0.965)
PTEN,phosphatase and tensin homolog,ENSG00000171862,5728,P60484,CellAge|GenAge,2,FALSE,,,TRUE,Cells_EBV-transformed_lymphocytes,62.45,62.45,Low tissue specificity,Cell type enhanced,122,TP53(0.999)|PIK3R1(0.997)|PIK3CA(0.995)|PTK2(0.995)|SPOP(0.99)
PTGER2,prostaglandin E receptor 2,ENSG00000125384,5732,P43116,SenMayo,1,TRUE,Ptger2,87.1508,TRUE,Cells_Cultured_fibroblasts,54.87,54.87,Tissue enhanced,Cell type enhanced,2,PTGES(0.737)|PTGS2(0.712)
PTGES,prostaglandin E synthase,ENSG00000148344,9536,O14684,SenMayo,1,TRUE,Ptges,79.6053,TRUE,Skin_Sun_Exposed_Lower_leg,65.05,65.05,Tissue enhanced,Cell type enhanced,3,PTGS2(0.982)|IL1B(0.78)|PTGER2(0.737)
PTGS2,prostaglandin-endoperoxide synthase 2,ENSG00000073756,5743,P35354,CellAge|GenAge,2,TRUE,Ptgs2,86.755,TRUE,Lung,21.88,21.88,Tissue enhanced,Cell type enhanced,51,PTGES(0.982)|CXCL8(0.975)|IL1B(0.974)|TP53(0.974)|IL6(0.96)
PTK2,protein tyrosine kinase 2,ENSG00000169398,5747,Q05397,CellAge|GenAge,2,TRUE,Ptk2,96.8978,TRUE,Artery_Tibial,51.69,51.69,Low tissue specificity,Cell type enhanced,42,EGFR(0.999)|GRB2(0.999)|SRC(0.999)|PTPN11(0.997)|PTEN(0.995)
PTK2B,protein tyrosine kinase 2 beta,ENSG00000120899,2185,Q14289,GenAge,1,TRUE,Ptk2b,95.441,TRUE,Cells_EBV-transformed_lymphocytes,233.14,233.14,Tissue enhanced,Cell type enhanced,9,SRC(0.999)|TGFB1I1(0.987)|PTK2(0.984)|RHOA(0.952)|GRB2(0.951)
PTPN1,protein tyrosine phosphatase non-receptor type 1,ENSG00000196396,5770,P18031,CellAge|GenAge,2,TRUE,Ptpn1,82.5287,TRUE,Cells_EBV-transformed_lymphocytes,108.96,108.96,Low tissue specificity,Cell type enhanced,22,INSR(0.999)|EGFR(0.997)|IRS1(0.995)|IGF1R(0.993)|JAK2(0.98)
PTPN11,protein tyrosine phosphatase non-receptor type 11,ENSG00000179295,5781,Q06124,GenAge,1,TRUE,Ptpn11,99.4941,TRUE,Cells_Cultured_fibroblasts,111.38,111.38,Low tissue specificity,Low cell type specificity,65,EGFR(0.999)|GRB2(0.999)|IRS1(0.999)|PDGFRB(0.999)|PECAM1(0.999)
PTPN6,protein tyrosine phosphatase non-receptor type 6,ENSG00000111679,5777,P29350,CellAge,1,TRUE,Ptpn6,94.4538,TRUE,Cells_EBV-transformed_lymphocytes,442.65,442.65,Tissue enhanced,Cell type enhanced,21,SYK(0.995)|JAK2(0.984)|PECAM1(0.979)|KDR(0.972)|PIK3R1(0.971)
PTTG1,"PTTG1 regulator of sister chromatid separation, securin",ENSG00000164611,9232,O95997,CellAge,1,TRUE,Pttg1,71.2871,TRUE,Testis,167.25,167.25,Tissue enhanced,Cell type enhanced,45,ESPL1(0.999)|FZR1(0.99)|CDK1(0.985)|CCNB1(0.984)|UBE2C(0.98)
PURB,purine rich element binding protein B,ENSG00000146676,5814,Q96QR8,CellAge,1,TRUE,Purb,98.0769,TRUE,Brain_Cerebellar_Hemisphere,51.24,51.24,Low tissue specificity,Low cell type specificity,1,YBX1(0.715)
PYCR1,pyrroline-5-carboxylate reductase 1,ENSG00000183010,5831,P32322,GenAge,1,TRUE,Pycr1,88.4013,TRUE,Cells_Cultured_fibroblasts,80.35,80.35,Tissue enhanced,Cell type enhanced,3,PRODH(0.976)|NUDT5(0.848)|ATP6V0A2(0.809)
PYGL,glycogen phosphorylase L,ENSG00000100504,5836,P06737,CellAge,1,TRUE,Pygl,94.5691,TRUE,Whole_Blood,310.81,310.81,Tissue enhanced,Cell type enhanced,1,INS(0.759)
RACGAP1,Rac GTPase activating protein 1,ENSG00000161800,29127,Q9H0H5,CellAge,1,TRUE,Racgap1,84.3354,TRUE,Cells_EBV-transformed_lymphocytes,65.2,65.2,Tissue enhanced,Cell type enhanced,32,ECT2(0.999)|ANLN(0.997)|KIF20A(0.997)|CDC42(0.979)|RHOA(0.979)
RACK1,receptor for activated C kinase 1,ENSG00000204628,10399,P63244,CellAge,1,TRUE,Rack1,100,TRUE,Ovary,1199.34,1199.34,Low tissue specificity,Cell type enhanced,29,EEF2(0.999)|RPL11(0.999)|RPS14(0.999)|RPS27A(0.999)|RPS9(0.999)
RAD21,RAD21 cohesin complex component,ENSG00000164754,5885,O60216,CellAge,1,TRUE,Rad21,97.1474,TRUE,Cells_EBV-transformed_lymphocytes,148.71,148.71,Low tissue specificity,Cell type enhanced,26,SMC1A(0.999)|STAG2(0.999)|ESPL1(0.997)|YY1(0.902)|PLK1(0.894)
RAD23B,RAD23 nucleotide excision repair protein B,ENSG00000119318,5887,P54727,CellAge,1,TRUE,Rad23b,90.4645,TRUE,Cells_Cultured_fibroblasts,176.17,176.17,Low tissue specificity,Cell type enhanced,39,XPC(0.999)|ERCC1(0.998)|XPA(0.997)|ERCC4(0.99)|ERCC5(0.981)
RAD50,RAD50 double strand break repair protein,ENSG00000113522,10111,Q92878,Reactome,1,TRUE,Rad50,92.3018,TRUE,Cells_EBV-transformed_lymphocytes,36.1,36.1,Low tissue specificity,Group enriched,27,BRCA1(0.999)|MRE11(0.999)|NBN(0.999)|ATM(0.99)|MDC1(0.947)
RAD51,RAD51 recombinase,ENSG00000051180,5888,Q06609,GenAge,1,TRUE,Rad51,98.8201,TRUE,Cells_EBV-transformed_lymphocytes,26.51,26.51,Tissue enhanced,Cell type enhanced,104,ATRX(0.999)|BRCA1(0.999)|BRCA2(0.999)|RAD52(0.999)|TP53(0.999)
RAD51C,RAD51 paralog C,ENSG00000108384,5889,O43502,CellAge,1,TRUE,Rad51c,83.7766,TRUE,Testis,13.81,13.81,Low tissue specificity,Cell type enhanced,27,BRCA2(0.999)|RAD51(0.996)|BRCA1(0.98)|BRIP1(0.941)|FANCD2(0.934)
RAD52,RAD52 DNA repair protein,ENSG00000002016,5893,P43351,GenAge,1,TRUE,Rad52,70.3349,TRUE,Ovary,22.37,22.37,Low tissue specificity,Cell type enhanced,46,RAD51(0.999)|RPA1(0.999)|WRN(0.996)|ATRX(0.993)|BRCA2(0.993)
RAE1,ribonucleic acid export 1,ENSG00000101146,8480,P78406,GenAge,1,TRUE,Rae1,98.6413,TRUE,Testis,102.13,102.13,Tissue enhanced,Cell type enhanced,9,TPR(0.944)|BUB1(0.939)|BUB1B(0.935)|MAGOHB(0.825)|XPO1(0.784)
RAF1,"Raf-1 proto-oncogene, serine/threonine kinase",ENSG00000132155,5894,P04049,CellAge,1,TRUE,Raf1,97.6852,TRUE,Muscle_Skeletal,152.17,152.17,Tissue enhanced,Cell type enhanced,46,BRAF(0.999)|HRAS(0.999)|MAP2K1(0.999)|NRAS(0.999)|YWHAZ(0.999)
RAN,"RAN, member RAS oncogene family",ENSG00000132341,5901,P62826,CellAge,1,TRUE,Ran,100,TRUE,Cells_EBV-transformed_lymphocytes,557.02,557.02,Low tissue specificity,Cell type enhanced,12,NUTF2(0.999)|RCC1(0.999)|XPO1(0.999)|EEF1A1(0.973)|UBE2I(0.942)
RANBP9,RAN binding protein 9,ENSG00000010017,10048,Q96S59,CellAge,1,TRUE,Ranbp9,93.2785,TRUE,Testis,150.74,150.74,Low tissue specificity,Cell type enhanced,2,AXL(0.875)|MET(0.716)
RAP1GAP,RAP1 GTPase activating protein,ENSG00000076864,5909,P47736,CellAge,1,TRUE,Rap1gap,96.5309,TRUE,Thyroid,337.5,337.5,Tissue enhanced,Cell type enhanced,0,
RAPGEF4,Rap guanine nucleotide exchange factor 4,ENSG00000091428,11069,Q8WZA2,CellAge,1,TRUE,Rapgef4,97.3294,TRUE,Brain_Cortex,191.5,191.5,Tissue enriched,Cell type enhanced,9,ADCY5(0.955)|ARRB1(0.944)|RRAS2(0.927)|RASSF5(0.921)|MAPK8(0.919)
RARB,retinoic acid receptor beta,ENSG00000077092,5915,P10826,CellAge,1,TRUE,Rarb,98.4375,FALSE,Esophagus_Muscularis,24.35,24.35,Low tissue specificity,Cell type enhanced,6,MED1(0.937)|RASSF1(0.789)|NCOR2(0.757)|CYP26A1(0.739)|RBP1(0.71)
RASSF1,Ras association domain family member 1,ENSG00000068028,11186,Q9NS23,CellAge,1,TRUE,Rassf1,90.8824,TRUE,Nerve_Tibial,94,94,Low tissue specificity,Cell type enhanced,16,STK4(0.998)|RASSF5(0.996)|HRAS(0.992)|NRAS(0.96)|XPA(0.949)
RASSF4,Ras association domain family member 4,ENSG00000107551,83937,Q9H2L5,CellAge,1,TRUE,Rassf4,84.1122,TRUE,Thyroid,212.24,212.24,Tissue enhanced,Cell type enhanced,1,STK4(0.789)
RASSF5,Ras association domain family member 5,ENSG00000266094,83593,Q8WWW0,CellAge,1,TRUE,Rassf5,84.4498,TRUE,Whole_Blood,72.42,72.42,Tissue enhanced,Cell type enhanced,10,HRAS(0.999)|STK4(0.999)|RASSF1(0.996)|NRAS(0.957)|MDM2(0.942)
RB1,RB transcriptional corepressor 1,ENSG00000139687,5925,P06400,CellAge|GenAge|Reactome,3,TRUE,Rb1,90.625,TRUE,Cells_EBV-transformed_lymphocytes,60.61,60.61,Low tissue specificity,Cell type enhanced,75,CDK2(0.999)|CDK4(0.999)|E2F1(0.999)|E2F2(0.999)|HDAC1(0.999)
RBBP4,"RB binding protein 4, chromatin remodeling factor",ENSG00000162521,5928,Q09028,CellAge|Reactome,2,TRUE,Rbbp4,100,TRUE,Cells_EBV-transformed_lymphocytes,85.72,85.72,Low tissue specificity,Low cell type specificity,74,CHAF1B(0.999)|EED(0.999)|EZH2(0.999)|HDAC1(0.999)|HDAC2(0.999)
RBBP7,"RB binding protein 7, chromatin remodeling factor",ENSG00000102054,5931,Q16576,Reactome,1,TRUE,Rbbp7,99.7647,TRUE,Adrenal_Gland,250.38,250.38,Low tissue specificity,Cell type enhanced,60,EED(0.999)|EZH2(0.999)|HDAC1(0.999)|HDAC2(0.999)|RBBP4(0.999)
RBL1,RB transcriptional corepressor like 1,ENSG00000080839,5933,P28749,CellAge,1,TRUE,Rbl1,90.3558,TRUE,Cells_EBV-transformed_lymphocytes,13.77,13.77,Tissue enhanced,Cell type enhanced,27,TFDP1(0.996)|CDK2(0.995)|E2F1(0.994)|E2F3(0.985)|E2F2(0.983)
RBL2,RB transcriptional corepressor like 2,ENSG00000103479,5934,Q08999,CellAge,1,TRUE,Rbl2,90.7814,TRUE,Artery_Tibial,74.73,74.73,Low tissue specificity,Cell type enhanced,35,CDK2(0.998)|CCND3(0.995)|E2F1(0.991)|HDAC1(0.991)|CCNE1(0.99)
RBM38,RNA binding motif protein 38,ENSG00000132819,55544,Q9H0Z9,CellAge,1,TRUE,Rbm38,61.0879,TRUE,Whole_Blood,204.72,204.72,Tissue enhanced,Cell type enhanced,3,ELAVL1(0.818)|EIF4E(0.733)|MDM2(0.701)
RBM39,RNA binding motif protein 39,ENSG00000131051,9584,Q14498,CellAge,1,TRUE,Rbm39,98.6792,TRUE,Ovary,243.85,243.85,Tissue enhanced,Low cell type specificity,9,DDB1(0.977)|DHX9(0.909)|SRSF1(0.83)|SRSF3(0.828)|HNRNPC(0.79)
RBP1,retinol binding protein 1,ENSG00000114115,5947,P09455,CellAge,1,TRUE,Rbp1,65.9898,TRUE,Ovary,534.33,534.33,Tissue enhanced,Cell type enhanced,2,CYP26A1(0.719)|RARB(0.71)
RBP2,retinol binding protein 2,ENSG00000114113,5948,P50120,CellAge,1,TRUE,Rbp2,91.0448,TRUE,Small_Intestine_Terminal_Ileum,96.27,96.27,Tissue enriched,Cell type enriched,1,CYP26A1(0.813)
RBPJ,recombination signal binding protein for immunoglobulin kappa J region,ENSG00000168214,3516,Q06330,CellAge,1,TRUE,Rbpj,98.9733,TRUE,Uterus,58.72,58.72,Low tissue specificity,Cell type enhanced,22,NOTCH1(0.999)|NCOR2(0.998)|NOTCH3(0.998)|HDAC1(0.986)|EP300(0.98)
RBX1,ring-box 1,ENSG00000100387,9978,P62877,CellAge,1,TRUE,Rbx1,100,TRUE,Cells_EBV-transformed_lymphocytes,169.61,169.61,Low tissue specificity,Cell type enhanced,55,CUL4B(0.999)|DDB1(0.999)|DDB2(0.999)|KEAP1(0.999)|SKP2(0.999)
RCC1,regulator of chromosome condensation 1,ENSG00000180198,1104,P18754,CellAge,1,TRUE,Rcc1,93.8242,TRUE,Cells_EBV-transformed_lymphocytes,68.66,68.66,Low tissue specificity,Cell type enriched,9,RAN(0.999)|H2AC20(0.982)|H2AC18(0.981)|H2BC21(0.98)|XPO1(0.927)
RECK,reversion inducing cysteine rich protein with kazal motifs,ENSG00000122707,8434,O95980,CellAge,1,TRUE,Reck,93.5118,TRUE,Cells_Cultured_fibroblasts,89.21,89.21,Low tissue specificity,Cell type enhanced,5,MMP14(0.894)|PDCD4(0.793)|MMP2(0.783)|SPARC(0.761)|MMP9(0.758)
RECQL4,RecQ like helicase 4,ENSG00000160957,9401,O94761,CellAge|GenAge,2,TRUE,Recql4,65.7285,TRUE,Testis,56.54,56.54,Tissue enhanced,Cell type enhanced,34,CDC45(0.982)|RAD51(0.982)|FEN1(0.981)|TOP3A(0.962)|TOPBP1(0.948)
RELA,"RELA proto-oncogene, NF-kB subunit",ENSG00000173039,5970,Q04206,CellAge|GenAge|Reactome,3,TRUE,Rela,88.7477,TRUE,Artery_Tibial,113.14,113.14,Low tissue specificity,Cell type enhanced,103,BRD4(0.999)|CHUK(0.999)|CREBBP(0.999)|EP300(0.999)|IKBKB(0.999)
RELB,"RELB proto-oncogene, NF-kB subunit",ENSG00000104856,5971,Q01201,CellAge,1,TRUE,Relb,85.3195,TRUE,Cells_EBV-transformed_lymphocytes,53.13,53.13,Low tissue specificity,Cell type enhanced,14,NFKB1(0.999)|NFKB2(0.999)|RELA(0.999)|CHUK(0.995)|NFKBIA(0.995)
RET,ret proto-oncogene,ENSG00000165731,5979,P07949,GenAge,1,TRUE,Ret,79.2639,TRUE,Brain_Substantia_nigra,6.3,6.3,Tissue enhanced,Cell type enhanced,21,SHC1(0.983)|GDF15(0.958)|GRB2(0.952)|PIK3R1(0.898)|PIK3CA(0.891)
RGN,regucalcin,ENSG00000130988,9104,Q15493,GenAge,1,TRUE,Rgn,88.6288,TRUE,Adrenal_Gland,162.05,162.05,Group enriched,Cell type enhanced,2,CAT(0.86)|PARK7(0.834)
RHOA,ras homolog family member A,ENSG00000067560,387,P61586,CellAge,1,TRUE,Rhoa,99.4819,TRUE,Artery_Tibial,994.22,994.22,Low tissue specificity,Cell type enhanced,69,ANLN(0.999)|ARHGAP1(0.999)|SRC(0.992)|MAPK8(0.988)|PTK2(0.983)
RICTOR,RPTOR independent companion of MTOR complex 2,ENSG00000164327,253260,Q6R327,GenAge,1,TRUE,Rictor,95.4333,TRUE,Uterus,23.18,23.18,Low tissue specificity,Cell type enhanced,29,DEPTOR(0.999)|MTOR(0.999)|RPTOR(0.999)|AKT1S1(0.993)|AKT1(0.992)
RING1,ring finger protein 1,ENSG00000206287,6015,Q06587,Reactome,1,FALSE,,,FALSE,,,,,,54,BMI1(0.999)|CBX2(0.999)|CBX4(0.999)|CBX7(0.999)|CBX8(0.999)
RNASEH2A,ribonuclease H2 subunit A,ENSG00000104889,10535,O75792,CellAge,1,TRUE,Rnaseh2a,86.9565,TRUE,Cells_EBV-transformed_lymphocytes,81.26,81.26,Low tissue specificity,Cell type enhanced,13,RNASEH2B(0.999)|SAMHD1(0.967)|PCNA(0.943)|FEN1(0.902)|MCM7(0.863)
RNASEH2B,ribonuclease H2 subunit B,ENSG00000136104,79621,Q5TBB1,CellAge,1,TRUE,Rnaseh2b,80.7692,TRUE,Cells_EBV-transformed_lymphocytes,17.91,17.91,Tissue enhanced,Cell type enhanced,4,RNASEH2A(0.999)|SAMHD1(0.95)|PCNA(0.931)|FEN1(0.76)
RNASEL,ribonuclease L,ENSG00000135828,6041,Q05823,CellAge,1,TRUE,Rnasel,63.9676,FALSE,Ovary,12.38,12.38,Low tissue specificity,Cell type enhanced,7,EIF2AK2(0.911)|STAT1(0.804)|ANG(0.74)|SAMHD1(0.72)|IFNB1(0.719)
RNF2,ring finger protein 2,ENSG00000121481,6045,Q99496,Reactome,1,TRUE,Rnf2,99.7024,TRUE,Cells_Cultured_fibroblasts,15.95,15.95,Low tissue specificity,Cell type enhanced,63,BMI1(0.999)|CBX2(0.999)|CBX4(0.999)|CBX7(0.999)|KDM2B(0.999)
ROMO1,reactive oxygen species modulator 1,ENSG00000125995,140823,P60602,CellAge,1,TRUE,Romo1,100,TRUE,Cells_Cultured_fibroblasts,164.02,164.02,Low tissue specificity,Cell type enhanced,2,HSPA9(0.733)|COX5B(0.708)
RPA1,replication protein A1,ENSG00000132383,6117,P27694,GenAge,1,TRUE,Rpa1,85.5519,TRUE,Cells_EBV-transformed_lymphocytes,83.54,83.54,Low tissue specificity,Cell type enhanced,60,BLM(0.999)|RAD52(0.999)|TP53(0.999)|WRN(0.999)|CLSPN(0.998)
RPL11,ribosomal protein L11,ENSG00000142676,6135,P62913,CellAge,1,TRUE,Rpl11,100,TRUE,Ovary,1874.88,1874.88,Low tissue specificity,Cell type enhanced,25,EEF2(0.999)|MDM2(0.999)|RACK1(0.999)|RPS14(0.999)|RPS27A(0.999)
RPS14,ribosomal protein S14,ENSG00000164587,6208,P62263,CellAge,1,TRUE,Rps14,100,TRUE,Ovary,1372.37,1372.37,Low tissue specificity,Cell type enhanced,17,RACK1(0.999)|RPL11(0.999)|RPS27A(0.999)|RPS9(0.999)|UBA52(0.999)
RPS27A,ribosomal protein S27a,ENSG00000143947,6233,P62979,Reactome,1,TRUE,Rps27a,99.359,FALSE,Ovary,3010.8,3010.8,Low tissue specificity,Cell type enhanced,102,RACK1(0.999)|RPL11(0.999)|RPS14(0.999)|RPS9(0.999)|UBA52(0.999)
RPS6KA1,ribosomal protein S6 kinase A1,ENSG00000281877,6195,Q15418,Reactome,1,FALSE,,,FALSE,,,,,,20,MAPK1(0.999)|MAPK3(0.99)|S100B(0.975)|NRAS(0.952)|HRAS(0.946)
RPS6KA2,ribosomal protein S6 kinase A2,ENSG00000071242,6196,Q15349,Reactome,1,TRUE,Rps6ka2,95.6344,TRUE,Cells_Cultured_fibroblasts,92.31,92.31,Low tissue specificity,Cell type enhanced,11,MAPK1(0.991)|MAPK3(0.986)|NRAS(0.935)|HRAS(0.926)|MAPK7(0.921)
RPS6KA3,ribosomal protein S6 kinase A3,ENSG00000177189,6197,P51812,Reactome,1,TRUE,Rps6ka3,99.0541,TRUE,Lung,37.42,37.42,Low tissue specificity,Cell type enhanced,14,MAPK1(0.989)|MAPK3(0.984)|MAPK7(0.951)|NRAS(0.942)|HRAS(0.934)
RPS6KA5,ribosomal protein S6 kinase A5,ENSG00000100784,9252,O75582,SenMayo,1,TRUE,Rps6ka5,96.01,TRUE,Brain_Cerebellar_Hemisphere,8.11,8.11,Low tissue specificity,Cell type enhanced,12,CREB1(0.988)|MAPK14(0.976)|H3-4(0.959)|ATF2(0.956)|MAPK11(0.942)
RPS6KB1,ribosomal protein S6 kinase B1,ENSG00000108443,6198,P23443,CellAge,1,TRUE,Rps6kb1,99.4286,FALSE,Ovary,22.94,22.94,Low tissue specificity,Cell type enhanced,42,MTOR(0.999)|RPTOR(0.999)|IRS1(0.994)|DEPTOR(0.991)|AKT1S1(0.99)
RPS9,ribosomal protein S9,ENSG00000278081,6203,P46781,CellAge,1,FALSE,,,FALSE,,,,,,20,EEF2(0.999)|RACK1(0.999)|RPL11(0.999)|RPS14(0.999)|RPS27A(0.999)
RPTOR,regulatory associated protein of MTOR complex 1,ENSG00000141564,57521,Q8N122,CellAge,1,TRUE,Rptor,96.6292,TRUE,Colon_Sigmoid,18.86,18.86,Low tissue specificity,Cell type enhanced,27,AKT1S1(0.999)|DEPTOR(0.999)|EIF4EBP1(0.999)|MTOR(0.999)|RICTOR(0.999)
RRAD,"RRAD, Ras related glycolysis inhibitor and calcium channel regulator",ENSG00000166592,6236,P55042,CellAge,1,TRUE,Rrad,91.8831,TRUE,Muscle_Skeletal,332.46,332.46,Group enriched,Cell type enhanced,2,EGR1(0.803)|EGR2(0.796)
RRAS2,RAS related 2,ENSG00000133818,22800,P62070,CellAge,1,TRUE,Rras2,100,TRUE,Cells_Cultured_fibroblasts,66.88,66.88,Low tissue specificity,Cell type enhanced,12,PIK3CA(0.988)|RAF1(0.985)|NF1(0.958)|BRAF(0.951)|RAPGEF4(0.927)
RRM1,ribonucleotide reductase catalytic subunit M1,ENSG00000167325,6240,P23921,CellAge,1,TRUE,Rrm1,97.601,TRUE,Cells_EBV-transformed_lymphocytes,104.05,104.05,Low tissue specificity,Cell type enhanced,18,RRM2(0.999)|RRM2B(0.999)|TYMS(0.976)|PCNA(0.933)|MCM7(0.921)
RRM2,ribonucleotide reductase regulatory subunit M2,ENSG00000171848,6241,P31350,CellAge,1,TRUE,Rrm2,91.5167,TRUE,Cells_EBV-transformed_lymphocytes,174.49,174.49,Tissue enhanced,Cell type enhanced,47,RRM1(0.999)|RRM2B(0.997)|CDK1(0.973)|TOP2A(0.956)|KIF11(0.947)
RRM2B,ribonucleotide reductase regulatory TP53 inducible subunit M2B,ENSG00000048392,50484,Q7LG56,CellAge,1,TRUE,Rrm2b,93.4473,TRUE,Cells_EBV-transformed_lymphocytes,35.21,35.21,Low tissue specificity,Cell type enhanced,9,RRM1(0.999)|RRM2(0.997)|TP53(0.992)|POLG(0.943)|TXN(0.811)
RRP8,ribosomal RNA processing 8,ENSG00000132275,23378,O43159,CellAge,1,TRUE,Rrp8,75.8772,TRUE,Colon_Sigmoid,15.28,15.28,Low tissue specificity,Low cell type specificity,8,SIRT1(0.996)|SUV39H1(0.996)|SIRT2(0.911)|BMS1(0.855)|PDCD11(0.803)
RTN4,reticulon 4,ENSG00000115310,57142,Q9NQC3,CellAge,1,TRUE,Rtn4,75.2517,TRUE,Cells_Cultured_fibroblasts,330.95,330.95,Low tissue specificity,Cell type enhanced,4,NGFR(0.977)|RHOA(0.811)|APP(0.739)|BCL2(0.737)
RUNX1,RUNX family transcription factor 1,ENSG00000159216,861,Q01196,CellAge,1,TRUE,Runx1,91.6667,TRUE,Minor_Salivary_Gland,31,31,Tissue enhanced,Cell type enhanced,56,ETS1(0.999)|FOXP3(0.999)|HDAC1(0.998)|CEBPA(0.994)|SPI1(0.993)
RUVBL2,RuvB like AAA ATPase 2,ENSG00000183207,10856,Q9Y230,CellAge,1,TRUE,Ruvbl2,99.568,TRUE,Testis,340.98,340.98,Tissue enhanced,Cell type enhanced,39,EP400(0.999)|KAT5(0.999)|TRRAP(0.999)|YEATS4(0.998)|CTNNB1(0.997)
S100A6,S100 calcium binding protein A6,ENSG00000197956,6277,P06703,CellAge,1,TRUE,S100a6,95.5556,TRUE,Cells_Cultured_fibroblasts,4057.42,4057.42,Low tissue specificity,Cell type enhanced,5,RB1(0.921)|GAPDH(0.843)|TP53(0.842)|SIAH1(0.78)|S100B(0.775)
S100B,S100 calcium binding protein B,ENSG00000160307,6285,P04271,GenAge,1,TRUE,S100b,98.913,TRUE,Brain_Spinal_cord_cervical_c-1,3673.92,3673.92,Tissue enriched,Cell type enhanced,10,TP53(0.995)|FGF2(0.986)|RPS6KA1(0.975)|MAPT(0.906)|TLR4(0.844)
SALL1,spalt like transcription factor 1,ENSG00000103449,6299,Q9NSC2,CellAge,1,TRUE,Sall1,90.6344,TRUE,Kidney_Medulla,50.78,50.78,Tissue enhanced,Cell type enhanced,5,NANOG(0.972)|SOX2(0.891)|TERF1(0.835)|POU5F1(0.819)|SIX1(0.81)
SAMHD1,SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1,ENSG00000101347,25939,Q9Y3Z3,CellAge,1,TRUE,Samhd1,72.8435,TRUE,Nerve_Tibial,453.45,453.45,Low tissue specificity,Cell type enhanced,10,RNASEH2A(0.967)|RNASEH2B(0.95)|CCNA2(0.911)|CDK1(0.85)|IRF7(0.814)
SAT2,spermidine/spermine N1-acetyltransferase family member 2,ENSG00000141504,112483,Q96F10,CellAge,1,TRUE,Sat2,80,FALSE,Ovary,316.98,316.98,Low tissue specificity,Cell type enhanced,1,HIF1A(0.814)
SCAMP4,secretory carrier membrane protein 4,ENSG00000227500,113178,Q969E2,SenMayo,1,TRUE,Scamp4,83.4061,TRUE,Thyroid,82.76,82.76,Low tissue specificity,Cell type enhanced,0,
SDC1,syndecan 1,ENSG00000115884,6382,P18827,CellAge,1,TRUE,Sdc1,76.7742,FALSE,Skin_Not_Sun_Exposed_Suprapubic,657.8,657.8,Tissue enhanced,Cell type enhanced,27,FGF2(0.997)|MMP9(0.968)|APOE(0.932)|ITGB3(0.932)|HMGB1(0.921)
SDHC,succinate dehydrogenase complex subunit C,ENSG00000143252,6391,Q99643,GenAge,1,TRUE,Sdhc,79.2899,TRUE,Cells_Cultured_fibroblasts,21.19,21.19,Low tissue specificity,Cell type enhanced,7,MT-CO1(0.951)|ACLY(0.95)|HTT(0.912)|COX5B(0.886)|GAPDH(0.847)
SELENBP1,selenium binding protein 1,ENSG00000143416,8991,Q13228,CellAge,1,TRUE,Selenbp1,87.7119,TRUE,Colon_Transverse,628.65,628.65,Tissue enhanced,Cell type enhanced,2,CBS(0.848)|ENO1(0.751)
SELENOH,selenoprotein H,ENSG00000211450,280636,Q8IZQ5,CellAge,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,181.08,181.08,Low tissue specificity,Cell type enhanced,0,
SELPLG,selectin P ligand,ENSG00000110876,6404,Q14242,SenMayo,1,TRUE,Selplg,46.8447,FALSE,Whole_Blood,639.54,639.54,Tissue enhanced,Cell type enhanced,6,ICAM1(0.991)|CD40LG(0.983)|MSN(0.793)|CD34(0.784)|TNF(0.716)
SEMA3F,semaphorin 3F,ENSG00000001617,6405,Q13275,SenMayo,1,TRUE,Sema3f,92.6115,TRUE,Esophagus_Mucosa,111.23,111.23,Tissue enhanced,Cell type enhanced,0,
SENP1,SUMO specific peptidase 1,ENSG00000079387,29843,Q9P0U3,CellAge,1,TRUE,Senp1,88.0435,TRUE,Testis,62.35,62.35,Tissue enhanced,Cell type enhanced,4,SUMO1(0.999)|SUMO2(0.999)|SUMO3(0.976)|UBE2I(0.917)
SENP7,SUMO specific peptidase 7,ENSG00000138468,57337,Q9BQF6,CellAge,1,TRUE,Senp7,70.4762,TRUE,Ovary,34.59,34.59,Low tissue specificity,Low cell type specificity,5,SUMO2(0.959)|SUMO1(0.931)|CBX5(0.855)|SUMO3(0.77)|UBE2I(0.725)
SERPINB2,serpin family B member 2,ENSG00000197632,5055,P05120,CellAge,1,TRUE,Serpinb2,75.9036,FALSE,Esophagus_Mucosa,114.8,114.8,Tissue enhanced,Cell type enhanced,4,PLAT(0.989)|PLAU(0.986)|SERPINE1(0.958)|PLAUR(0.938)
SERPINB4,serpin family B member 4,ENSG00000206073,6318,P48594,SenMayo,1,TRUE,Serpinb3a,61.2821,FALSE,Vagina,132.6,132.6,Group enriched,Group enriched,0,
SERPINE1,serpin family E member 1,ENSG00000106366,5054,P05121,CellAge|GenAge|SenMayo,3,TRUE,Serpine1,78.8557,TRUE,Cells_Cultured_fibroblasts,2500.42,2500.42,Tissue enhanced,Cell type enhanced,40,PLAT(0.999)|PLAU(0.999)|PLAUR(0.994)|SERPINB2(0.958)|AGTR1(0.953)
SERPINE2,serpin family E member 2,ENSG00000135919,5270,P07093,SenMayo,1,TRUE,Serpine2,85.3904,TRUE,Cells_Cultured_fibroblasts,293.21,293.21,Group enriched,Cell type enhanced,3,PLAU(0.946)|PLAT(0.878)|PLAUR(0.735)
SETD1A,"SET domain containing 1A, histone lysine methyltransferase",ENSG00000099381,9739,O15047,CellAge,1,FALSE,,,TRUE,Testis,52.75,52.75,Low tissue specificity,Low cell type specificity,21,DPY30(0.999)|CTNNB1(0.947)|KDM1A(0.936)|H3-4(0.917)|DOT1L(0.911)
SFN,stratifin,ENSG00000175793,2810,P31947,CellAge,1,TRUE,Sfn,97.5806,FALSE,Esophagus_Mucosa,3222.79,3222.79,Tissue enhanced,Group enriched,26,TP53(0.999)|MDM2(0.989)|ESR1(0.984)|FOXO1(0.984)|MDM4(0.977)
SFRP1,secreted frizzled related protein 1,ENSG00000104332,6422,Q8N474,CellAge,1,TRUE,Sfrp1,94.9045,TRUE,Cervix_Ectocervix,305.86,305.86,Tissue enhanced,Cell type enhanced,7,WNT5A(0.963)|WNT7B(0.963)|WNT2(0.928)|WIF1(0.924)|WNT16(0.906)
SGK1,serum/glucocorticoid regulated kinase 1,ENSG00000118515,6446,O00141,CellAge,1,TRUE,Sgk1,75.6654,FALSE,Ovary,140.73,140.73,Tissue enhanced,Cell type enhanced,16,MTOR(0.992)|PDPK1(0.988)|FOXO3(0.979)|FOXO1(0.967)|FOXO4(0.952)
SHC1,SHC adaptor protein 1,ENSG00000160691,6464,P29353,GenAge,1,TRUE,Shc1,94.3493,TRUE,Cells_Cultured_fibroblasts,277.82,277.82,Low tissue specificity,Cell type enhanced,57,EGFR(0.999)|ERBB2(0.999)|GRB2(0.999)|IGF1R(0.999)|SRC(0.999)
SIAH1,siah E3 ubiquitin protein ligase 1,ENSG00000196470,6477,Q8IUQ4,CellAge,1,TRUE,Siah1a,99.6454,TRUE,Testis,12.3,12.3,Low tissue specificity,Cell type enhanced,9,GAPDH(0.997)|CTNNB1(0.991)|HIPK2(0.942)|GSK3B(0.935)|GSK3A(0.911)
SIK1,salt inducible kinase 1,ENSG00000142178,150094,P57059,CellAge,1,TRUE,Sik1,81.2261,TRUE,Skin_Not_Sun_Exposed_Suprapubic,14.4,14.4,Low tissue specificity,Cell type enhanced,1,CREB1(0.725)
SIN3A,SIN3 transcription regulator family member A,ENSG00000169375,25942,Q96ST3,GenAge,1,TRUE,Sin3a,98.1147,TRUE,Uterus,26.54,26.54,Low tissue specificity,Cell type enhanced,56,HDAC1(0.999)|HDAC2(0.999)|ING2(0.999)|MECP2(0.999)|NCOR1(0.999)
SIN3B,SIN3 transcription regulator family member B,ENSG00000127511,23309,O75182,CellAge,1,TRUE,Sin3b,89.7345,TRUE,Uterus,88.07,88.07,Low tissue specificity,Cell type enhanced,15,HDAC1(0.999)|HDAC2(0.999)|RBBP7(0.998)|RBBP4(0.997)|ARID4B(0.993)
SIRT1,sirtuin 1,ENSG00000096717,23411,Q96EB6,CellAge|GenAge,2,TRUE,Sirt1,86.2115,TRUE,Testis,33.9,33.9,Low tissue specificity,Cell type enhanced,110,CLOCK(0.999)|FOXO1(0.999)|FOXO3(0.999)|PPARGC1A(0.999)|SUV39H1(0.999)
SIRT2,sirtuin 2,ENSG00000283100,22933,Q8IXJ6,CellAge,1,FALSE,,,FALSE,,,,,,20,FOXO1(0.961)|NAMPT(0.958)|SIRT1(0.956)|SUV39H1(0.946)|RAN(0.926)
SIRT3,sirtuin 3,ENSG00000142082,23410,Q9NTG7,CellAge|GenAge,2,TRUE,Sirt3,54.6366,TRUE,Testis,31.44,31.44,Low tissue specificity,Low cell type specificity,14,FOXO3(0.987)|PPARGC1A(0.98)|NAMPT(0.97)|H3-4(0.95)|H3C1(0.936)
SIRT6,sirtuin 6,ENSG00000077463,51548,Q8N6T7,CellAge|GenAge,2,TRUE,Sirt6,83.3803,TRUE,Brain_Cerebellar_Hemisphere,30.28,30.28,Low tissue specificity,Cell type enriched,19,HIF1A(0.98)|RELA(0.969)|NAMPT(0.964)|MYC(0.957)|WRN(0.912)
SIRT7,sirtuin 7,ENSG00000187531,51547,Q9NRC8,CellAge|GenAge,2,TRUE,Sirt7,94.25,TRUE,Esophagus_Mucosa,83.96,83.96,Low tissue specificity,Cell type enhanced,10,NAMPT(0.948)|TP53(0.904)|EPAS1(0.892)|MYBBP1A(0.89)|DDB1(0.872)
SIX1,SIX homeobox 1,ENSG00000126778,6495,Q15475,CellAge,1,TRUE,Six1,99.2958,TRUE,Pituitary,30.73,30.73,Tissue enhanced,Cell type enhanced,2,SALL1(0.81)|MEOX1(0.714)
SIX6,SIX homeobox 6,ENSG00000184302,4990,O95475,CellAge,1,TRUE,Six6,97.9675,TRUE,Pituitary,55.22,55.22,Tissue enriched,Cell type enhanced,1,OTX2(0.894)
SKP2,S-phase kinase associated protein 2,ENSG00000145604,6502,Q13309,CellAge,1,TRUE,Skp2,86.3208,TRUE,Cells_Cultured_fibroblasts,30.04,30.04,Tissue enhanced,Cell type enhanced,45,CCNA1(0.999)|CCNA2(0.999)|CDK2(0.999)|CDKN1B(0.999)|RBX1(0.999)
SLC13A1,solute carrier family 13 member 1,ENSG00000081800,6561,Q9BZW2,GenAge,1,TRUE,Slc13a1,81.0084,TRUE,Kidney_Cortex,6.94,6.94,Tissue enriched,Group enriched,0,
SLC13A3,solute carrier family 13 member 3,ENSG00000158296,64849,Q8WWT9,CellAge,1,TRUE,Slc13a3,87.7076,TRUE,Kidney_Cortex,73.67,73.67,Tissue enriched,Cell type enriched,0,
SLC16A7,solute carrier family 16 member 7,ENSG00000118596,9194,O60669,CellAge,1,TRUE,Slc16a7,72.1757,TRUE,Cells_Cultured_fibroblasts,9.08,9.08,Tissue enhanced,Cell type enhanced,0,
SLC25A5,solute carrier family 25 member 5,ENSG00000005022,292,P05141,CellAge,1,TRUE,Slc25a5,98.3222,TRUE,Cells_EBV-transformed_lymphocytes,688.38,688.38,Low tissue specificity,Cell type enhanced,6,ERCC2(0.909)|PHB(0.857)|BCL2(0.781)|BAK1(0.738)|BAX(0.738)
SLC31A2,solute carrier family 31 member 2,ENSG00000136867,1318,O15432,CellAge,1,TRUE,Slc31a2,73.4266,TRUE,Brain_Spinal_cord_cervical_c-1,12.92,12.92,Tissue enhanced,Cell type enhanced,0,
SLC52A1,solute carrier family 52 member 1,ENSG00000132517,55065,Q9NWF4,CellAge,1,TRUE,Slc52a2,80.5804,TRUE,Skin_Sun_Exposed_Lower_leg,6.17,6.17,Group enriched,Cell type enriched,0,
SLC5A2,solute carrier family 5 member 2,ENSG00000140675,6524,P31639,CellAge,1,TRUE,Slc5a2,90.4762,TRUE,Kidney_Cortex,36.01,36.01,Tissue enriched,Cell type enhanced,2,DPP4(0.909)|INS(0.885)
SMAD1,SMAD family member 1,ENSG00000170365,4086,Q15797,CellAge,1,TRUE,Smad1,99.1398,TRUE,Uterus,16.88,16.88,Low tissue specificity,Cell type enhanced,14,SMAD6(0.985)|SMAD2(0.979)|MAPK1(0.965)|YAP1(0.962)|SMAD3(0.954)
SMAD2,SMAD family member 2,ENSG00000175387,4087,Q15796,CellAge,1,TRUE,Smad2,93.576,FALSE,Thyroid,9.3,9.3,Low tissue specificity,Low cell type specificity,67,SMAD3(0.999)|SMURF2(0.999)|TGFBR1(0.999)|CTNNB1(0.998)|TGFBR2(0.998)
SMAD3,SMAD family member 3,ENSG00000166949,4088,P84022,CellAge,1,TRUE,Smad3,100,TRUE,Cervix_Ectocervix,59.9,59.9,Low tissue specificity,Cell type enhanced,94,CTNNB1(0.999)|EP300(0.999)|SMAD2(0.999)|TGFBR1(0.999)|TGFBR2(0.998)
SMAD5,SMAD family member 5,ENSG00000113658,4090,Q99717,CellAge,1,TRUE,Smad5,98.9247,TRUE,Ovary,38.96,38.96,Low tissue specificity,Low cell type specificity,17,BMPR2(0.984)|SMAD3(0.98)|SMAD2(0.972)|SMURF2(0.954)|SMAD6(0.953)
SMAD6,SMAD family member 6,ENSG00000137834,4091,O43541,CellAge,1,TRUE,Smad6,93.5484,TRUE,Lung,33.97,33.97,Tissue enhanced,Cell type enhanced,14,SMURF2(0.998)|SMAD1(0.985)|TGFBR1(0.982)|SMAD2(0.972)|SMAD5(0.953)
SMARCA2,SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2,ENSG00000080503,6595,P51531,CellAge,1,TRUE,Smarca2,96.0377,TRUE,Ovary,43.13,43.13,Low tissue specificity,Cell type enhanced,32,ARID1A(0.999)|ARID1B(0.999)|PBRM1(0.999)|SMARCA4(0.999)|SMARCB1(0.999)
SMARCA4,SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4,ENSG00000127616,6597,P51532,CellAge,1,TRUE,Smarca4,97.2678,TRUE,Testis,81.65,81.65,Low tissue specificity,Cell type enhanced,86,ARID1A(0.999)|ARID1B(0.999)|BRD7(0.999)|HDAC2(0.999)|PBRM1(0.999)
SMARCB1,SWI/SNF related BAF chromatin remodeling complex subunit B1,ENSG00000099956,6598,Q12824,CellAge,1,TRUE,Smarcb1,100,TRUE,Cells_EBV-transformed_lymphocytes,136.38,136.38,Low tissue specificity,Cell type enhanced,33,ARID1A(0.999)|ARID1B(0.999)|PBRM1(0.999)|SMARCA2(0.999)|SMARCA4(0.999)
SMARCD1,SWI/SNF related BAF chromatin remodeling complex subunit D1,ENSG00000066117,6602,Q96GM5,CellAge,1,TRUE,Smarcd1,99.4175,TRUE,Cells_EBV-transformed_lymphocytes,58.27,58.27,Low tissue specificity,Low cell type specificity,23,ARID1A(0.999)|BRD7(0.999)|PBRM1(0.999)|SMARCA2(0.999)|SMARCA4(0.999)
SMC1A,structural maintenance of chromosomes 1A,ENSG00000072501,8243,Q14683,CellAge,1,TRUE,Smc1a,99.2701,TRUE,Cells_EBV-transformed_lymphocytes,50.58,50.58,Low tissue specificity,Cell type enhanced,20,RAD21(0.999)|STAG2(0.999)|ESPL1(0.975)|BRCA1(0.93)|PLK1(0.924)
SMC2,structural maintenance of chromosomes 2,ENSG00000136824,10592,O95347,CellAge,1,TRUE,Smc2,91.6458,TRUE,Cells_EBV-transformed_lymphocytes,45.29,45.29,Tissue enhanced,Cell type enhanced,20,NCAPG2(0.994)|NCAPH2(0.99)|KIF11(0.967)|TOP2A(0.928)|SMC1A(0.874)
SMG1,SMG1 nonsense mediated mRNA decay associated PI3K related kinase,ENSG00000157106,23049,Q96Q15,CellAge,1,TRUE,Smg1,97.6782,TRUE,Brain_Cerebellar_Hemisphere,47.75,47.75,Low tissue specificity,Cell type enhanced,5,RICTOR(0.96)|RPTOR(0.956)|TRRAP(0.841)|RUVBL2(0.823)|ATM(0.705)
SMURF2,SMAD specific E3 ubiquitin protein ligase 2,ENSG00000108854,64750,Q9HAU4,CellAge,1,TRUE,Smurf2,99.1979,TRUE,Cells_Cultured_fibroblasts,34.41,34.41,Low tissue specificity,Cell type enhanced,19,SMAD2(0.999)|TGFBR1(0.999)|SMAD6(0.998)|SMAD3(0.997)|UBC(0.995)
SNAI1,snail family transcriptional repressor 1,ENSG00000124216,6615,O95863,CellAge,1,TRUE,Snai1,87.5,TRUE,Adipose_Visceral_Omentum,38.37,38.37,Tissue enhanced,Cell type enhanced,54,HDAC1(0.999)|EZH2(0.998)|HDAC2(0.998)|KDM1A(0.998)|DNMT1(0.995)
SNCG,synuclein gamma,ENSG00000173267,6623,O76070,GenAge,1,TRUE,Sncg,83.4646,TRUE,Brain_Hypothalamus,367.51,367.51,Tissue enhanced,Cell type enhanced,0,
SOCS1,suppressor of cytokine signaling 1,ENSG00000185338,8651,O15524,CellAge,1,TRUE,Socs1,95.7346,TRUE,Cells_EBV-transformed_lymphocytes,52.37,52.37,Low tissue specificity,Cell type enhanced,36,JAK2(0.999)|TYK2(0.999)|IRS2(0.985)|IRS1(0.983)|INSR(0.97)
SOCS2,suppressor of cytokine signaling 2,ENSG00000120833,8835,O14508,GenAge,1,TRUE,Socs2,93.4343,TRUE,Cervix_Ectocervix,71.8,71.8,Low tissue specificity,Cell type enhanced,14,GHR(0.993)|JAK2(0.974)|SOCS1(0.967)|IRS1(0.96)|EPOR(0.943)
SOD1,superoxide dismutase 1,ENSG00000142168,6647,P00441,CellAge|GenAge,2,TRUE,Sod1,83.7662,TRUE,Liver,378.48,378.48,Tissue enhanced,Cell type enhanced,34,BCL2(0.998)|PARK7(0.997)|SOD2(0.994)|HSPA5(0.975)|PPARGC1A(0.958)
SOD2,superoxide dismutase 2,ENSG00000291237,6648,P04179,CellAge|GenAge,2,TRUE,Sod2,90.0901,TRUE,,,,Tissue enhanced,Cell type enhanced,22,SOD1(0.994)|FOXO3(0.974)|PPARGC1A(0.973)|PARK7(0.923)|CAT(0.908)
SORBS2,sorbin and SH3 domain containing 2,ENSG00000154556,8470,O94875,CellAge,1,TRUE,Sorbs2,80.2308,TRUE,Artery_Tibial,194.96,194.96,Tissue enhanced,Cell type enhanced,1,ABL1(0.838)
SOX1,SRY-box transcription factor 1,ENSG00000182968,6656,O00570,CellAge,1,TRUE,Sox1,91.5601,TRUE,Brain_Hypothalamus,5.19,5.19,Tissue enriched,Cell type enhanced,5,OTX2(0.807)|NANOG(0.776)|SOX2(0.771)|POU5F1(0.752)|KLF4(0.747)
SOX2,SRY-box transcription factor 2,ENSG00000181449,6657,P48431,CellAge,1,TRUE,Sox2,98.4227,TRUE,Brain_Amygdala,69.77,69.77,Tissue enhanced,Cell type enhanced,64,NANOG(0.999)|POU5F1(0.999)|KLF4(0.998)|CTNNB1(0.991)|HDAC1(0.966)
SOX4,SRY-box transcription factor 4,ENSG00000124766,6659,Q06945,CellAge,1,TRUE,Sox4,81.2236,TRUE,Ovary,65.56,65.56,Tissue enhanced,Cell type enhanced,6,POU5F1(0.922)|EZH2(0.874)|CTNNB1(0.873)|UBE2I(0.792)|MYC(0.722)
SOX5,SRY-box transcription factor 5,ENSG00000134532,6660,P35711,CellAge,1,TRUE,Sox5,96.9856,TRUE,Testis,15.34,15.34,Tissue enhanced,Cell type enhanced,1,CTNNB1(0.855)
SP1,Sp1 transcription factor,ENSG00000185591,6667,P08047,CellAge|GenAge|Reactome,3,TRUE,Sp1,95.0318,TRUE,Uterus,57.69,57.69,Low tissue specificity,Cell type enhanced,49,EP300(0.999)|ESR1(0.999)|JUN(0.996)|TBP(0.994)|TP53(0.994)
SPAG9,sperm associated antigen 9,ENSG00000008294,9043,O60271,CellAge,1,TRUE,Spag9,95.6094,TRUE,Nerve_Tibial,85.35,85.35,Low tissue specificity,Cell type enhanced,5,MAPK8(0.781)|POLG(0.749)|MAPK14(0.733)|JUN(0.732)|MAP2K6(0.723)
SPARC,secreted protein acidic and cysteine rich,ENSG00000113140,6678,P09486,CellAge,1,TRUE,Sparc,92.4092,TRUE,Artery_Aorta,2798.48,2798.48,Low tissue specificity,Cell type enhanced,7,SPP1(0.984)|CCN2(0.764)|RECK(0.761)|COL18A1(0.757)|TGFB1(0.722)
SPHK1,sphingosine kinase 1,ENSG00000176170,8877,Q9NYA1,CellAge,1,TRUE,Sphk1,80.7292,TRUE,Nerve_Tibial,56.57,56.57,Low tissue specificity,Cell type enhanced,8,ASAH1(0.98)|ACER2(0.968)|MAPK3(0.951)|PLD2(0.932)|PRKCA(0.932)
SPI1,Spi-1 proto-oncogene,ENSG00000066336,6688,P17947,CellAge,1,TRUE,Spi1,88.5185,TRUE,Whole_Blood,873.49,873.49,Group enriched,Cell type enhanced,22,JUN(0.993)|RUNX1(0.993)|CEBPA(0.99)|FOS(0.975)|IRF1(0.974)
SPIN1,spindlin 1,ENSG00000106723,10927,Q9Y657,CellAge,1,TRUE,Spin1,99.2366,TRUE,Cervix_Endocervix,136.76,136.76,Low tissue specificity,Low cell type specificity,4,H3-4(0.959)|H3-3A(0.9)|H3C1(0.9)|H3C15(0.9)
SPOP,speckle type BTB/POZ protein,ENSG00000121067,8405,O43791,CellAge,1,TRUE,Spop,100,TRUE,Colon_Sigmoid,106.33,106.33,Low tissue specificity,Cell type enhanced,17,RBX1(0.996)|GLI1(0.99)|PTEN(0.99)|TP53BP1(0.955)|AR(0.953)
SPP1,secreted phosphoprotein 1,ENSG00000118785,6696,P10451,SenMayo,1,TRUE,Spp1,63.3758,FALSE,Kidney_Medulla,3688.84,3688.84,Tissue enhanced,Cell type enriched,29,MMP3(0.997)|ITGB3(0.994)|SPARC(0.984)|MMP9(0.947)|MMP7(0.941)
SPRTN,SprT-like N-terminal domain,ENSG00000010072,83932,Q9H040,GenAge,1,TRUE,Sprtn,70.9611,TRUE,Testis,12.16,12.16,Low tissue specificity,Cell type enhanced,5,PCNA(0.992)|VCP(0.976)|UBC(0.864)|PTEN(0.809)|POLD1(0.772)
SPX,spexin hormone,ENSG00000134548,80763,Q9BT56,SenMayo,1,TRUE,Spx,67.2414,TRUE,Brain_Substantia_nigra,44.43,44.43,Tissue enhanced,Cell type enhanced,1,CLPP(0.722)
SQSTM1,sequestosome 1,ENSG00000161011,8878,Q13501,GenAge,1,TRUE,Sqstm1,91.1364,TRUE,Muscle_Skeletal,155.16,155.16,Tissue enhanced,Cell type enhanced,53,KEAP1(0.999)|NBR1(0.999)|UBC(0.999)|TBK1(0.995)|ATG5(0.991)
SRC,"SRC proto-oncogene, non-receptor tyrosine kinase",ENSG00000197122,6714,P12931,CellAge,1,TRUE,Src,98.694,TRUE,Uterus,59.33,59.33,Low tissue specificity,Cell type enhanced,137,ARRB1(0.999)|CAV1(0.999)|CTNNB1(0.999)|EGFR(0.999)|ERBB2(0.999)
SREBF1,sterol regulatory element binding transcription factor 1,ENSG00000072310,6720,P36956,CellAge,1,TRUE,Srebf1,79.8605,TRUE,Adrenal_Gland,285.19,285.19,Tissue enhanced,Cell type enhanced,30,FASN(0.983)|PPARG(0.982)|EP300(0.963)|HMGCR(0.956)|LMNA(0.935)
SRF,serum response factor,ENSG00000112658,6722,P11831,CellAge,1,TRUE,Srf,95.8661,TRUE,Colon_Sigmoid,164.8,164.8,Low tissue specificity,Cell type enhanced,19,MRTFA(0.999)|GATA4(0.991)|MRTFB(0.978)|FOS(0.95)|ETS1(0.919)
SRSF1,serine and arginine rich splicing factor 1,ENSG00000136450,6426,Q07955,CellAge,1,TRUE,Srsf1,100,TRUE,Cells_EBV-transformed_lymphocytes,281.17,281.17,Low tissue specificity,Cell type enhanced,26,SRSF2(0.997)|TRA2B(0.997)|SRSF3(0.994)|HNRNPA1(0.993)|PTBP1(0.983)
SRSF2,serine and arginine rich splicing factor 2,ENSG00000161547,6427,Q01130,CellAge,1,TRUE,Srsf2,100,TRUE,Cells_EBV-transformed_lymphocytes,305.86,305.86,Low tissue specificity,Cell type enhanced,20,SRSF3(0.999)|TRA2B(0.998)|SRSF1(0.997)|HNRNPC(0.9)|RUNX1(0.858)
SRSF3,serine and arginine rich splicing factor 3,ENSG00000112081,6428,P84103,CellAge,1,TRUE,Srsf3,100,TRUE,Ovary,169.27,169.27,Low tissue specificity,Low cell type specificity,16,SRSF2(0.999)|TRA2B(0.998)|SRSF1(0.994)|HNRNPC(0.981)|HNRNPA1(0.97)
SST,somatostatin,ENSG00000157005,6750,P61278,GenAge,1,TRUE,Sst,96.5517,TRUE,Brain_Hypothalamus,309.21,309.21,Group enriched,Group enriched,16,SSTR3(0.997)|GHRH(0.964)|INS(0.953)|GH1(0.87)|CREB1(0.866)
SSTR3,somatostatin receptor 3,ENSG00000278195,6753,P32745,GenAge,1,TRUE,Sstr3,85.6459,TRUE,Testis,17.96,17.96,Tissue enhanced,Cell type enhanced,1,SST(0.997)
SSX2,SSX family member 2,ENSG00000241476,6757,Q16385,CellAge,1,TRUE,Ssxb9,33.5106,FALSE,Testis,0.14,0.14,Tissue enriched,Not detected,1,SMARCA2(0.808)
STAG2,STAG2 cohesin complex component,ENSG00000101972,10735,Q8N3U4,CellAge,1,TRUE,Stag2,99.1325,TRUE,Cells_EBV-transformed_lymphocytes,49.87,49.87,Low tissue specificity,Cell type enhanced,7,RAD21(0.999)|SMC1A(0.999)|ESPL1(0.987)|PLK1(0.817)|EP300(0.794)
STAT1,signal transducer and activator of transcription 1,ENSG00000115415,6772,P42224,CellAge,1,TRUE,Stat1,93.4667,TRUE,Cells_EBV-transformed_lymphocytes,501.45,501.45,Low tissue specificity,Cell type enhanced,96,CREBBP(0.999)|IRF1(0.999)|JAK2(0.999)|STAT3(0.999)|EP300(0.998)
STAT3,signal transducer and activator of transcription 3,ENSG00000168610,6774,P40763,CellAge|GenAge|Reactome,3,TRUE,Stat3,97.5325,TRUE,Lung,172.98,172.98,Low tissue specificity,Cell type enhanced,176,EP300(0.999)|JAK2(0.999)|SRC(0.999)|STAT1(0.999)|EGFR(0.998)
STAT5A,signal transducer and activator of transcription 5A,ENSG00000126561,6776,P42229,CellAge|GenAge,2,TRUE,Stat5a,96.2217,TRUE,Adipose_Subcutaneous,83.59,83.59,Tissue enhanced,Cell type enhanced,63,JAK2(0.999)|EGFR(0.998)|STAT3(0.997)|EPOR(0.989)|TYK2(0.982)
STAT5B,signal transducer and activator of transcription 5B,ENSG00000173757,6777,P51692,CellAge|GenAge,2,TRUE,Stat5b,96.5693,TRUE,Uterus,155.54,155.54,Low tissue specificity,Cell type enriched,55,JAK2(0.999)|STAT3(0.998)|EGFR(0.997)|TYK2(0.984)|ABL1(0.983)
STAT6,signal transducer and activator of transcription 6,ENSG00000166888,6778,P42226,CellAge,1,TRUE,Stat6,85.4782,TRUE,Ovary,219.35,219.35,Low tissue specificity,Cell type enhanced,36,JAK2(0.991)|IL13(0.971)|IL2RG(0.969)|TYK2(0.964)|CREBBP(0.957)
STIM1,stromal interaction molecule 1,ENSG00000167323,6786,Q13586,CellAge,1,TRUE,Stim1,92.4581,TRUE,Esophagus_Mucosa,61.23,61.23,Low tissue specificity,Cell type enhanced,5,ORAI1(0.999)|ITPR1(0.953)|ITPR3(0.952)|CAV1(0.868)|ITPR2(0.827)
STK11,serine/threonine kinase 11,ENSG00000118046,6794,Q15831,GenAge,1,TRUE,Stk11,90.5312,TRUE,Testis,119.64,119.64,Low tissue specificity,Cell type enhanced,27,PTEN(0.979)|PRKAA2(0.978)|TP53(0.97)|FOXO3(0.96)|FOXO1(0.955)
STK32C,serine/threonine kinase 32C,ENSG00000165752,282974,Q86UX6,CellAge,1,TRUE,Stk32c,91.358,FALSE,Brain_Frontal_Cortex_BA9,35.59,35.59,Tissue enhanced,Cell type enhanced,0,
STK4,serine/threonine kinase 4,ENSG00000101109,6789,Q13043,CellAge,1,TRUE,Stk4,97.3306,FALSE,Cells_EBV-transformed_lymphocytes,72.66,72.66,Tissue enhanced,Cell type enhanced,10,RASSF5(0.999)|RASSF1(0.998)|FOXO3(0.966)|LATS2(0.965)|FOXO1(0.952)
STK40,serine/threonine kinase 40,ENSG00000196182,83931,Q8N2I9,CellAge,1,TRUE,Stk40,97.2414,TRUE,Testis,89.18,89.18,Low tissue specificity,Cell type enhanced,2,FOS(0.816)|JUNB(0.76)
STN1,STN1 subunit of CST complex,ENSG00000107960,79991,Q9H668,CellAge,1,TRUE,Stn1,71.4674,TRUE,Esophagus_Mucosa,53.65,53.65,Low tissue specificity,Cell type enhanced,22,RPA1(0.998)|MED1(0.994)|MED12(0.994)|POLA1(0.978)|XRCC6(0.934)
STUB1,STIP1 homology and U-box containing protein 1,ENSG00000103266,10273,Q9UNE7,CellAge|GenAge,2,TRUE,Stub1,97.6898,TRUE,Brain_Cerebellar_Hemisphere,136.09,136.09,Low tissue specificity,Cell type enhanced,41,BAG3(0.999)|HSP90AA1(0.999)|HSP90AB1(0.999)|HSPA8(0.999)|UBE2D1(0.999)
SUMO1,small ubiquitin like modifier 1,ENSG00000116030,7341,P63165,GenAge,1,TRUE,Sumo1,86.1386,TRUE,Cells_Cultured_fibroblasts,126.72,126.72,Low tissue specificity,Low cell type specificity,53,PML(0.999)|SENP1(0.999)|UBE2I(0.999)|CREBBP(0.998)|TP53(0.996)
SUMO2,small ubiquitin like modifier 2,ENSG00000188612,6613,P61956,CellAge,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,135.98,135.98,Low tissue specificity,Cell type enhanced,43,SENP1(0.999)|UBE2I(0.999)|SUMO1(0.994)|ATF7IP(0.979)|TP53(0.965)
SUMO3,small ubiquitin like modifier 3,ENSG00000184900,6612,P55854,CellAge,1,TRUE,Sumo3,90.2913,FALSE,Cells_Cultured_fibroblasts,153.13,153.13,Low tissue specificity,Cell type enhanced,10,UBE2I(0.999)|SENP1(0.976)|SUMO2(0.903)|PCNA(0.831)|SENP7(0.77)
SUN1,Sad1 and UNC84 domain containing 1,ENSG00000164828,23353,O94901,GenAge,1,TRUE,Sun1,69.8089,TRUE,Cervix_Ectocervix,180.98,180.98,Low tissue specificity,Cell type enhanced,6,EMD(0.998)|LMNA(0.997)|LMNB1(0.982)|CDK2(0.954)|ZMPSTE24(0.795)
SUPT5H,"SPT5 homolog, DSIF elongation factor subunit",ENSG00000196235,6829,O00267,CellAge,1,TRUE,Supt5,96.8721,TRUE,Testis,222.46,222.46,Low tissue specificity,Low cell type specificity,16,LEO1(0.999)|CDK7(0.951)|ERCC6(0.948)|ELOA(0.943)|H2BC11(0.892)
SUV39H1,SUV39H1 histone lysine methyltransferase,ENSG00000101945,6839,O43463,CellAge,1,TRUE,Suv39h1,95.3884,TRUE,Cells_EBV-transformed_lymphocytes,20.93,20.93,Low tissue specificity,Cell type enhanced,41,CBX5(0.999)|SIRT1(0.999)|DNMT1(0.998)|DNMT3A(0.996)|RRP8(0.996)
SUZ12,SUZ12 polycomb repressive complex 2 subunit,ENSG00000178691,23512,Q15022,CellAge|Reactome,2,TRUE,Suz12,97.1583,TRUE,Cells_EBV-transformed_lymphocytes,60.83,60.83,Low tissue specificity,Low cell type specificity,57,EED(0.999)|EZH2(0.999)|RBBP4(0.999)|RBBP7(0.999)|RNF2(0.999)
SYK,spleen associated tyrosine kinase,ENSG00000165025,6850,P43405,CellAge,1,TRUE,Syk,91.4961,TRUE,Cells_EBV-transformed_lymphocytes,77.38,77.38,Tissue enhanced,Cell type enhanced,32,PLCG2(0.999)|SRC(0.999)|PTPN6(0.995)|GRB2(0.986)|PIK3R1(0.98)
SYT1,synaptotagmin 1,ENSG00000067715,6857,P21579,CellAge,1,TRUE,Syt1,97.6303,TRUE,Brain_Frontal_Cortex_BA9,323.32,323.32,Group enriched,Cell type enhanced,6,FGF1(0.978)|SPHK1(0.88)|HSPA8(0.847)|PSEN1(0.846)|CACNA1A(0.765)
SYT7,synaptotagmin 7,ENSG00000011347,9066,O43581,CellAge,1,TRUE,Syt7,87.3178,TRUE,Brain_Cerebellum,92.89,92.89,Tissue enhanced,Cell type enhanced,0,
TACC3,transforming acidic coiled-coil containing protein 3,ENSG00000013810,10460,Q9Y6A5,CellAge,1,TRUE,Tacc3,38.1862,TRUE,Testis,121.97,121.97,Tissue enhanced,Cell type enhanced,24,AURKA(0.998)|BUB1B(0.946)|FGFR3(0.94)|NOTCH3(0.908)|PLK1(0.884)
TAF1,TATA-box binding protein associated factor 1,ENSG00000147133,6872,P21675,GenAge,1,TRUE,Taf1,96.1025,TRUE,Uterus,26.46,26.46,Low tissue specificity,Low cell type specificity,24,TBP(0.999)|ERCC3(0.982)|ERCC2(0.981)|GTF2H2(0.979)|ASF1A(0.974)
TAGLN,transgelin,ENSG00000149591,6876,Q01995,CellAge,1,TRUE,Tagln,97.0149,TRUE,Artery_Tibial,7796.27,7796.27,Tissue enhanced,Cell type enhanced,3,SRF(0.807)|PDGFRB(0.767)|CCN2(0.756)
TBK1,TANK binding kinase 1,ENSG00000183735,29110,Q9UHD2,CellAge,1,TRUE,Tbk1,94.1015,TRUE,Cells_EBV-transformed_lymphocytes,50.25,50.25,Low tissue specificity,Cell type enhanced,32,IRF3(0.999)|MAVS(0.999)|IKBKG(0.998)|TNF(0.998)|TNFRSF1A(0.998)
TBP,TATA-box binding protein,ENSG00000112592,6908,P20226,GenAge,1,TRUE,Tbp,91.1504,TRUE,Testis,52.48,52.48,Low tissue specificity,Cell type enhanced,45,TAF1(0.999)|ERCC3(0.998)|TP53(0.997)|ERCC2(0.994)|SP1(0.994)
TBPL1,TATA-box binding protein like 1,ENSG00000028839,9519,P62380,CellAge,1,TRUE,Tbpl1,100,TRUE,Testis,97.63,97.63,Tissue enhanced,Cell type enhanced,5,TBP(0.941)|RBPJ(0.908)|SP1(0.907)|TAF1(0.786)|TERF1(0.766)
TBX2,T-box transcription factor 2,ENSG00000121068,6909,Q13207,CellAge,1,TRUE,Tbx2,94.9438,TRUE,Lung,224.42,224.42,Tissue enhanced,Cell type enhanced,0,
TBX3,T-box transcription factor 3,ENSG00000135111,6926,O15119,CellAge,1,TRUE,Tbx3,92.6694,TRUE,Adrenal_Gland,250.7,250.7,Tissue enhanced,Cell type enhanced,9,MAPK3(0.933)|MAPK1(0.911)|SOX2(0.907)|POU5F1(0.898)|NANOG(0.882)
TCF3,transcription factor 3,ENSG00000071564,6929,P15923,GenAge,1,TRUE,Tcf3,80.1223,TRUE,Cells_EBV-transformed_lymphocytes,103.54,103.54,Low tissue specificity,Cell type enhanced,11,RUNX1(0.975)|ID1(0.973)|CTNNB1(0.958)|EP300(0.941)|CREBBP(0.917)
TEAD1,TEA domain transcription factor 1,ENSG00000187079,7003,P28347,CellAge,1,TRUE,Tead1,95.7747,TRUE,Cells_Cultured_fibroblasts,92.4,92.4,Low tissue specificity,Cell type enhanced,8,YAP1(0.999)|TEAD4(0.922)|CCN2(0.843)|LATS1(0.817)|EGR2(0.773)
TEAD4,TEA domain transcription factor 4,ENSG00000197905,7004,Q15561,CellAge,1,TRUE,Tead4,92.1659,FALSE,Muscle_Skeletal,59.43,59.43,Tissue enhanced,Cell type enhanced,8,YAP1(0.999)|TEAD1(0.922)|SMAD3(0.899)|EP300(0.852)|CCN2(0.808)
TERC,telomerase RNA component,ENSG00000270141,7012,,GenAge,1,FALSE,,,FALSE,Kidney_Medulla,0.13,0.13,,,0,
TERF1,telomeric repeat binding factor 1,ENSG00000147601,7013,P54274,GenAge|Reactome,2,TRUE,Terf1,64.2369,TRUE,Nerve_Tibial,36.85,36.85,Low tissue specificity,Cell type enhanced,31,ACD(0.999)|POT1(0.999)|TERF2IP(0.999)|TINF2(0.999)|TERF2(0.998)
TERF2,telomeric repeat binding factor 2,ENSG00000132604,7014,Q15554,CellAge|GenAge|Reactome,3,TRUE,Terf2,84.5018,TRUE,Brain_Cerebellar_Hemisphere,31.47,31.47,Low tissue specificity,Low cell type specificity,24,ACD(0.999)|POT1(0.999)|TERF2IP(0.999)|TINF2(0.999)|TERF1(0.998)
TERF2IP,TERF2 interacting protein,ENSG00000166848,54386,Q9NYB0,Reactome,1,TRUE,Terf2ip,84.9624,TRUE,Brain_Cerebellar_Hemisphere,302.5,302.5,Low tissue specificity,Low cell type specificity,16,ACD(0.999)|POT1(0.999)|TERF1(0.999)|TERF2(0.999)|TINF2(0.999)
TERT,telomerase reverse transcriptase,ENSG00000164362,7015,O14746,CellAge|GenAge,2,TRUE,Tert,61.2191,TRUE,Testis,2.72,2.72,Not detected,Cell type enhanced,43,DKC1(0.999)|HSP90AA1(0.998)|CTNNB1(0.995)|RUVBL2(0.992)|POT1(0.99)
TFAP2A,transcription factor AP-2 alpha,ENSG00000137203,7020,P05549,GenAge,1,TRUE,Tfap2a,98.6333,TRUE,Skin_Not_Sun_Exposed_Suprapubic,63.16,63.16,Tissue enhanced,Cell type enhanced,16,MYC(0.938)|TP53(0.913)|ESR1(0.879)|SP1(0.876)|EP300(0.856)
TFDP1,transcription factor Dp-1,ENSG00000198176,7027,Q14186,CellAge|GenAge|Reactome,3,TRUE,Tfdp1,94.8781,TRUE,Cells_EBV-transformed_lymphocytes,147,147,Tissue enhanced,Cell type enhanced,32,E2F1(0.999)|RB1(0.999)|E2F3(0.996)|RBL1(0.996)|E2F2(0.989)
TFDP2,transcription factor Dp-2,ENSG00000114126,7029,Q14188,Reactome,1,TRUE,Tfdp2,95.0673,TRUE,Testis,23.42,23.42,Tissue enhanced,Cell type enhanced,17,E2F1(0.997)|RB1(0.987)|RBL2(0.983)|E2F2(0.982)|RBL1(0.982)
TFG,trafficking from ER to golgi regulator,ENSG00000114354,10342,Q92734,CellAge,1,TRUE,Tfg,93.75,TRUE,Cells_Cultured_fibroblasts,86.64,86.64,Low tissue specificity,Cell type enhanced,2,TPR(0.92)|GRB2(0.71)
TGFB1,transforming growth factor beta 1,ENSG00000105329,7040,P01137,GenAge,1,TRUE,Tgfb1,89.4872,TRUE,Whole_Blood,306.45,306.45,Low tissue specificity,Cell type enhanced,85,TGFBR1(0.999)|TGFBR2(0.999)|ENG(0.998)|SMAD3(0.99)|SMAD2(0.983)
TGFB1I1,transforming growth factor beta 1 induced transcript 1,ENSG00000140682,7041,O43294,CellAge,1,TRUE,Tgfb1i1,91.3232,FALSE,Uterus,512.58,512.58,Tissue enhanced,Cell type enhanced,6,PTK2B(0.987)|AR(0.942)|PTK2(0.917)|SMAD3(0.779)|ILK(0.745)
TGFB2,transforming growth factor beta 2,ENSG00000092969,7042,P61812,CellAge,1,TRUE,Tgfb2,95.8937,TRUE,Minor_Salivary_Gland,15.01,15.01,Low tissue specificity,Cell type enhanced,21,TGFBR2(0.999)|TGFBR1(0.998)|SMAD3(0.966)|TGFB1(0.957)|SMAD2(0.941)
TGFBI,transforming growth factor beta induced,ENSG00000120708,7045,Q15582,CellAge,1,TRUE,Tgfbi,90.6296,TRUE,Cells_Cultured_fibroblasts,2960.46,2960.46,Tissue enhanced,Cell type enhanced,2,ITGB3(0.771)|MMP9(0.738)
TGFBR1,transforming growth factor beta receptor 1,ENSG00000106799,7046,P36897,CellAge,1,TRUE,Tgfbr1,95.8251,TRUE,Artery_Aorta,47.91,47.91,Low tissue specificity,Cell type enhanced,29,GDF11(0.999)|SMAD2(0.999)|SMAD3(0.999)|SMURF2(0.999)|TGFB1(0.999)
TGFBR2,transforming growth factor beta receptor 2,ENSG00000163513,7048,P37173,CellAge,1,TRUE,Tgfbr2,92.2399,TRUE,Cells_Cultured_fibroblasts,377.2,377.2,Low tissue specificity,Cell type enhanced,23,TGFB1(0.999)|TGFB2(0.999)|TGFBR1(0.999)|SMAD2(0.998)|SMAD3(0.998)
THRB,thyroid hormone receptor beta,ENSG00000151090,7068,P10828,CellAge,1,TRUE,Thrb,81.128,TRUE,Artery_Aorta,38.66,38.66,Low tissue specificity,Cell type enhanced,12,NCOR1(0.982)|PIK3R1(0.966)|NCOR2(0.964)|MAPK3(0.916)|MAPK1(0.912)
TIGAR,TP53 induced glycolysis regulatory phosphatase,ENSG00000078237,57103,Q9NQ88,CellAge,1,TRUE,Tigar,72.2222,FALSE,Cells_EBV-transformed_lymphocytes,15.3,15.3,Low tissue specificity,Group enriched,2,TP53(0.981)|HK3(0.76)
TIMELESS,timeless circadian regulator,ENSG00000111602,8914,Q9UNS1,CellAge,1,TRUE,Timeless,83.6093,TRUE,Cells_EBV-transformed_lymphocytes,43.21,43.21,Low tissue specificity,Cell type enhanced,23,CLSPN(0.999)|CDC45(0.997)|RPA1(0.997)|MCM7(0.996)|CHEK1(0.993)
TIMP2,TIMP metallopeptidase inhibitor 2,ENSG00000035862,7077,P16035,SenMayo,1,TRUE,Timp2,98.1818,TRUE,Artery_Aorta,1214,1214,Low tissue specificity,Cell type enhanced,15,MMP14(0.999)|MMP2(0.999)|MMP9(0.998)|MMP10(0.981)|MMP3(0.967)
TINF2,TERF1 interacting nuclear factor 2,ENSG00000284915,26277,Q9BSI4,Reactome,1,FALSE,,,FALSE,,,,,,17,ACD(0.999)|POT1(0.999)|TERF1(0.999)|TERF2(0.999)|TERF2IP(0.999)
TLR10,toll like receptor 10,ENSG00000174123,81793,Q9BXR5,CellAge,1,FALSE,,,FALSE,Cells_EBV-transformed_lymphocytes,85.42,85.42,Tissue enriched,Group enriched,2,TLR2(0.992)|MYD88(0.964)
TLR2,toll like receptor 2,ENSG00000137462,7097,O60603,CellAge,1,TRUE,Tlr2,70.9184,TRUE,Whole_Blood,213.36,213.36,Tissue enhanced,Cell type enriched,55,MYD88(0.999)|TLR4(0.999)|HMGB1(0.998)|HSPA1B(0.998)|NFKB1(0.992)
TLR3,toll like receptor 3,ENSG00000164342,7098,O15455,CellAge,1,TRUE,Tlr3,79.4248,TRUE,Lung,5.09,5.09,Low tissue specificity,Cell type enhanced,38,MYD88(0.999)|IFNB1(0.995)|TBK1(0.993)|MAP3K7(0.992)|IRF3(0.978)
TLR4,toll like receptor 4,ENSG00000136869,7099,O00206,CellAge,1,TRUE,Tlr4,66.8653,FALSE,Spleen,40.49,40.49,Low tissue specificity,Cell type enhanced,80,HMGB1(0.999)|HSPD1(0.999)|IRAK4(0.999)|MYD88(0.999)|TLR2(0.999)
TLR8,toll like receptor 8,ENSG00000101916,51311,Q9NR97,CellAge,1,TRUE,Tlr8,71.0855,FALSE,Whole_Blood,44.07,44.07,Tissue enhanced,Cell type enriched,15,MYD88(0.999)|TLR3(0.939)|IRAK4(0.921)|TLR2(0.893)|IFNB1(0.835)
TMEM9B,TMEM9 domain family member B,ENSG00000175348,56674,Q9NQ34,CellAge,1,TRUE,Tmem9b,94.9495,TRUE,Thyroid,60.78,60.78,Low tissue specificity,Cell type enhanced,0,
TNF,tumor necrosis factor,ENSG00000228849,7124,P01375,GenAge|SenMayo,2,FALSE,,,FALSE,,,,,,138,CHUK(0.999)|IKBKB(0.999)|IKBKG(0.999)|MAP3K7(0.999)|NFKB1(0.999)
TNFRSF10C,TNF receptor superfamily member 10c,ENSG00000173535,8794,O14798,SenMayo,1,TRUE,Tnfrsf26,12.7413,TRUE,Whole_Blood,194.76,194.76,Tissue enhanced,Cell type enriched,0,
TNFRSF11B,TNF receptor superfamily member 11b,ENSG00000164761,4982,O00300,SenMayo,1,TRUE,Tnfrsf11b,85.5362,FALSE,Artery_Aorta,289.07,289.07,Group enriched,Cell type enriched,0,
TNFRSF1A,TNF receptor superfamily member 1A,ENSG00000067182,7132,P19438,SenMayo,1,TRUE,Tnfrsf1a,63.0769,TRUE,Adipose_Visceral_Omentum,161.99,161.99,Low tissue specificity,Cell type enhanced,46,CHUK(0.999)|FAS(0.999)|IKBKB(0.999)|IKBKG(0.999)|MAP3K7(0.999)
TNFRSF1B,TNF receptor superfamily member 1B,ENSG00000028137,7133,P20333,SenMayo,1,TRUE,Tnfrsf1b,62.4729,TRUE,Whole_Blood,474.28,474.28,Tissue enhanced,Cell type enhanced,13,TNF(0.999)|TNFRSF1A(0.999)|IL1B(0.914)|IL6(0.847)|IL10(0.843)
TNFSF13,TNF superfamily member 13,ENSG00000161955,8741,O75888,CellAge,1,TRUE,Tnfsf13,79.6,FALSE,Lung,96.18,96.18,Tissue enhanced,Cell type enhanced,2,TNFRSF1A(0.827)|XPO1(0.8)
TNFSF15,TNF superfamily member 15,ENSG00000181634,9966,O95150,CellAge,1,TRUE,Tnfsf15,66.5339,FALSE,Minor_Salivary_Gland,4.87,4.87,Tissue enhanced,Cell type enhanced,1,TNFRSF1A(0.734)
TNIK,TRAF2 and NCK interacting kinase,ENSG00000154310,23043,Q9UKE5,Reactome,1,TRUE,Tnik,93.2353,TRUE,Cells_EBV-transformed_lymphocytes,32.13,32.13,Low tissue specificity,Cell type enhanced,2,CTNNB1(0.869)|MINK1(0.774)
TNRC6A,trinucleotide repeat containing adaptor 6A,ENSG00000090905,27327,Q8NDV7,Reactome,1,TRUE,Tnrc6a,91.5902,TRUE,Brain_Cerebellar_Hemisphere,66.14,66.14,Low tissue specificity,Cell type enhanced,12,AGO1(0.999)|AGO2(0.999)|DICER1(0.998)|AGO4(0.99)|AGO3(0.987)
TNRC6B,trinucleotide repeat containing adaptor 6B,ENSG00000100354,23112,Q9UPQ9,Reactome,1,TRUE,Tnrc6b,93.0715,TRUE,Brain_Cerebellum,12.78,12.78,Low tissue specificity,Cell type enhanced,8,AGO2(0.998)|AGO1(0.994)|MOV10(0.988)|AGO3(0.968)|AGO4(0.935)
TNRC6C,trinucleotide repeat containing adaptor 6C,ENSG00000078687,57690,Q9HCJ0,Reactome,1,TRUE,Tnrc6c,88.9463,TRUE,Brain_Cerebellar_Hemisphere,34.56,34.56,Tissue enhanced,Cell type enhanced,6,AGO2(0.992)|AGO1(0.989)|AGO3(0.972)|AGO4(0.927)|CNOT6(0.819)
TOM1,target of myb1 membrane trafficking protein,ENSG00000100284,10043,O60784,CellAge,1,TRUE,Tom1,89.4309,TRUE,Muscle_Skeletal,135.62,135.62,Tissue enhanced,Cell type enhanced,4,UBC(0.984)|RPS27A(0.941)|UBB(0.915)|UBA52(0.903)
TOP1,DNA topoisomerase I,ENSG00000198900,7150,P11387,CellAge|GenAge,2,TRUE,Top1,97.2549,TRUE,Cells_EBV-transformed_lymphocytes,133.84,133.84,Low tissue specificity,Cell type enhanced,28,TOP2A(0.994)|TOP2B(0.981)|TP53(0.947)|PARP1(0.936)|SRSF1(0.912)
TOP2A,DNA topoisomerase II alpha,ENSG00000131747,7153,P11388,GenAge,1,TRUE,Top2a,89.484,TRUE,Cells_EBV-transformed_lymphocytes,150.71,150.71,Tissue enhanced,Cell type enhanced,63,CDK1(0.997)|TOP1(0.994)|CCNB1(0.989)|BUB1(0.982)|CCNA2(0.982)
TOP2B,DNA topoisomerase II beta,ENSG00000077097,7155,Q02880,GenAge,1,TRUE,Top2b,95.6335,TRUE,Brain_Cerebellar_Hemisphere,134.38,134.38,Low tissue specificity,Low cell type specificity,9,TOP1(0.981)|TOP2A(0.973)|TOPBP1(0.955)|SMC2(0.78)|AR(0.774)
TOP3A,DNA topoisomerase III alpha,ENSG00000177302,7156,Q13472,CellAge,1,TRUE,Top3a,86.9131,TRUE,Cells_EBV-transformed_lymphocytes,22.44,22.44,Low tissue specificity,Cell type enhanced,29,BLM(0.999)|RPA1(0.998)|WRN(0.996)|RAD51(0.968)|RECQL4(0.962)
TOP3B,DNA topoisomerase III beta,ENSG00000100038,8940,O95985,GenAge,1,TRUE,Top3b,95.5916,TRUE,Ovary,4.71,4.71,Low tissue specificity,Low cell type specificity,4,BLM(0.945)|WRN(0.931)|TOP3A(0.919)|RPA1(0.759)
TOPBP1,DNA topoisomerase II binding protein 1,ENSG00000163781,11073,Q92547,CellAge,1,TRUE,Topbp1,76.2155,TRUE,Cells_EBV-transformed_lymphocytes,55.21,55.21,Low tissue specificity,Cell type enhanced,33,BRCA1(0.999)|BRIP1(0.999)|CDC45(0.999)|TP53BP1(0.999)|ATR(0.996)
TP53,tumor protein p53,ENSG00000141510,7157,P04637,CellAge|GenAge|Reactome,3,TRUE,Trp53,77.3537,TRUE,Cells_EBV-transformed_lymphocytes,72.95,72.95,Low tissue specificity,Low cell type specificity,368,ATM(0.999)|BCL2(0.999)|BCL2L1(0.999)|BRCA1(0.999)|CDKN1A(0.999)
TP53BP1,tumor protein p53 binding protein 1,ENSG00000067369,7158,Q12888,CellAge|GenAge,2,TRUE,Trp53bp1,80.8295,TRUE,Pituitary,50.28,50.28,Low tissue specificity,Cell type enhanced,81,ATM(0.999)|BRCA1(0.999)|H2AC18(0.999)|H2AX(0.999)|MDC1(0.999)
TP53BP2,tumor protein p53 binding protein 2,ENSG00000143514,7159,Q13625,CellAge,1,TRUE,Trp53bp2,91.0053,TRUE,Artery_Aorta,39.5,39.5,Low tissue specificity,Cell type enhanced,9,TP53(0.999)|BCL2(0.99)|YAP1(0.986)|PPP1CA(0.984)|TP73(0.971)
TP53I3,tumor protein p53 inducible protein 3,ENSG00000115129,9540,Q53FA7,CellAge,1,FALSE,,,TRUE,Esophagus_Mucosa,107.66,107.66,Tissue enhanced,Cell type enhanced,2,TP53(0.903)|RPA1(0.747)
TP53INP1,tumor protein p53 inducible nuclear protein 1,ENSG00000164938,94241,Q96A56,CellAge,1,TRUE,Trp53inp1,87.0833,TRUE,Spleen,75.5,75.5,Tissue enhanced,Cell type enhanced,2,HIPK2(0.941)|TP53(0.935)
TP63,tumor protein p63,ENSG00000073282,8626,Q9H3D4,CellAge|GenAge,2,TRUE,Trp63,83.3824,TRUE,Skin_Not_Sun_Exposed_Suprapubic,138.85,138.85,Tissue enhanced,Cell type enhanced,9,TP73(0.997)|TP53(0.953)|SOX2(0.93)|MDM2(0.9)|EP300(0.85)
TP73,tumor protein p73,ENSG00000078900,7161,O15350,GenAge,1,TRUE,Trp73,83.9623,TRUE,Cells_EBV-transformed_lymphocytes,17.58,17.58,Tissue enhanced,Cell type enhanced,15,MDM2(0.998)|TP63(0.997)|YAP1(0.995)|TP53(0.985)|TP53BP2(0.971)
TPP1,tripeptidyl peptidase 1,ENSG00000166340,1200,O14773,CellAge,1,TRUE,Tpp1,88.0995,TRUE,Spleen,192.23,192.23,Low tissue specificity,Cell type enhanced,6,POT1(0.996)|TINF2(0.995)|TERF1(0.993)|CTSD(0.761)|TERF2IP(0.757)
TPP2,tripeptidyl peptidase 2,ENSG00000134900,7174,P29144,GenAge,1,TRUE,Tpp2,95.3249,TRUE,Testis,50.72,50.72,Low tissue specificity,Cell type enhanced,1,POLB(0.743)
TPR,"translocated promoter region, nuclear basket protein",ENSG00000047410,7175,P12270,CellAge,1,TRUE,Tpr,93.4405,TRUE,Testis,75.86,75.86,Low tissue specificity,Cell type enhanced,7,MAD1L1(0.973)|MCM3AP(0.964)|MAD2L1(0.947)|RAE1(0.944)|TFG(0.92)
TPX2,TPX2 microtubule nucleation factor,ENSG00000088325,22974,Q9ULW0,CellAge,1,TRUE,Tpx2,79.1165,TRUE,Cells_EBV-transformed_lymphocytes,113.34,113.34,Tissue enhanced,Cell type enhanced,36,AURKA(0.999)|KIF2C(0.999)|KIF20A(0.972)|KIF11(0.965)|UBE2C(0.965)
TRA2B,transformer 2 beta homolog,ENSG00000136527,6434,P62995,CellAge,1,TRUE,Tra2b,91.3194,TRUE,Cells_EBV-transformed_lymphocytes,142.26,142.26,Low tissue specificity,Low cell type specificity,10,SRSF2(0.998)|SRSF3(0.998)|SRSF1(0.997)|HNRNPC(0.968)|HNRNPA1(0.953)
TRAP1,TNF receptor associated protein 1,ENSG00000126602,10131,Q12931,GenAge,1,TRUE,Trap1,88.2102,TRUE,Cells_EBV-transformed_lymphocytes,94.3,94.3,Low tissue specificity,Cell type enhanced,5,PINK1(0.817)|HSPA9(0.793)|HSPA5(0.787)|HSPD1(0.754)|CLPP(0.725)
TRDMT1,tRNA aspartic acid methyltransferase 1,ENSG00000107614,1787,O14717,CellAge,1,TRUE,Trdmt1,81.3299,TRUE,Nerve_Tibial,4.82,4.82,Low tissue specificity,Cell type enhanced,3,DNMT3B(0.933)|DNMT3A(0.926)|NSUN2(0.883)
TRIM28,tripartite motif containing 28,ENSG00000130726,10155,Q13263,CellAge,1,TRUE,Trim28,93.8922,TRUE,Testis,351.67,351.67,Low tissue specificity,Cell type enhanced,32,CBX5(0.997)|DNMT1(0.985)|HDAC1(0.968)|UBE2I(0.96)|DNMT3A(0.942)
TRPM7,transient receptor potential cation channel subfamily M member 7,ENSG00000092439,54822,Q96QT4,CellAge,1,TRUE,Trpm7,94.1555,TRUE,Cells_EBV-transformed_lymphocytes,25.33,25.33,Tissue enriched,Cell type enhanced,1,TRPV1(0.747)
TRPM8,transient receptor potential cation channel subfamily M member 8,ENSG00000144481,79054,Q7Z2W7,CellAge,1,TRUE,Trpm8,93.75,FALSE,Prostate,14.1,14.1,Group enriched,Group enriched,3,TRPV1(0.994)|PPP1CA(0.9)|NGF(0.726)
TRPV1,transient receptor potential cation channel subfamily V member 1,ENSG00000196689,7442,Q8NER1,GenAge,1,TRUE,Trpv1,86.77,FALSE,Nerve_Tibial,29.62,29.62,Tissue enhanced,Cell type enhanced,6,TRPM8(0.994)|SRC(0.934)|NGF(0.853)|CNR1(0.781)|TRPM7(0.747)
TRRAP,transformation/transcription domain associated protein,ENSG00000196367,8295,Q9Y4A5,CellAge,1,TRUE,Trrap,98.3217,TRUE,Cells_EBV-transformed_lymphocytes,28.74,28.74,Low tissue specificity,Low cell type specificity,43,EP400(0.999)|KAT5(0.999)|MYC(0.999)|RUVBL2(0.999)|MORF4L1(0.998)
TSC22D1,TSC22 domain family member 1,ENSG00000102804,8848,Q15714,CellAge,1,TRUE,Tsc22d1,86.0205,TRUE,Artery_Tibial,323.48,323.48,Low tissue specificity,Cell type enhanced,0,
TTK,TTK protein kinase,ENSG00000112742,7272,P33981,CellAge,1,TRUE,Ttk,73.8623,TRUE,Testis,28.61,28.61,Group enriched,Cell type enhanced,42,BUB1(0.999)|MAD2L1(0.995)|BUB1B(0.991)|MAD1L1(0.987)|KIF11(0.984)
TUBGCP2,tubulin gamma complex component 2,ENSG00000130640,10844,Q9BSJ2,SenMayo,1,TRUE,Tubgcp2,91.2417,TRUE,Ovary,51.65,51.65,Low tissue specificity,Cell type enhanced,0,
TWIST1,twist family bHLH transcription factor 1,ENSG00000122691,7291,Q15672,CellAge,1,TRUE,Twist1,96.5347,FALSE,Cells_Cultured_fibroblasts,128.38,128.38,Tissue enhanced,Cell type enhanced,24,TP53(0.967)|TWIST2(0.939)|ZEB1(0.932)|SNAI1(0.901)|TCF3(0.897)
TWIST2,twist family bHLH transcription factor 2,ENSG00000233608,117581,Q8WVJ9,CellAge,1,TRUE,Twist2,100,TRUE,Cells_Cultured_fibroblasts,258.7,258.7,Tissue enhanced,Cell type enhanced,4,TWIST1(0.939)|TCF3(0.872)|SNAI1(0.853)|ZEB1(0.751)
TXN,thioredoxin,ENSG00000136810,7295,P10599,CellAge|GenAge|Reactome,3,TRUE,Txn1,87.619,TRUE,Esophagus_Mucosa,1026.32,1026.32,Tissue enhanced,Cell type enhanced,29,MAP3K5(0.999)|TXNIP(0.999)|PRDX1(0.99)|APEX1(0.983)|NFKB1(0.983)
TXNIP,thioredoxin interacting protein,ENSG00000265972,10628,Q9H3M7,CellAge,1,TRUE,Txnip,95.9079,TRUE,Adipose_Subcutaneous,2556.63,2556.63,Low tissue specificity,Cell type enhanced,11,TXN(0.999)|DDIT4(0.991)|PTPN11(0.972)|TP53(0.855)|MAP3K5(0.842)
TYK2,tyrosine kinase 2,ENSG00000105397,7297,P29597,CellAge,1,TRUE,Tyk2,78.6858,TRUE,Cells_EBV-transformed_lymphocytes,100.47,100.47,Low tissue specificity,Cell type enhanced,38,SOCS1(0.999)|JAK2(0.997)|STAT1(0.997)|STAT3(0.997)|IL6(0.986)
TYMS,thymidylate synthetase,ENSG00000176890,7298,P04818,CellAge,1,TRUE,Tyms,88.8179,TRUE,Cells_EBV-transformed_lymphocytes,198.02,198.02,Tissue enhanced,Cell type enhanced,31,MTHFD2(0.994)|RRM1(0.976)|TOP2A(0.96)|RRM2(0.939)|PCNA(0.913)
UBA52,ubiquitin A-52 residue ribosomal protein fusion product 1,ENSG00000221983,7311,P62987,Reactome,1,TRUE,Uba52,100,TRUE,Whole_Blood,503.37,503.37,Low tissue specificity,Cell type enhanced,78,RACK1(0.999)|RPL11(0.999)|RPS14(0.999)|RPS27A(0.999)|RPS9(0.999)
UBB,ubiquitin B,ENSG00000170315,7314,P0CG47,GenAge|Reactome,2,TRUE,Ubb,99.5633,TRUE,Testis,592,592,Low tissue specificity,Cell type enhanced,81,UBA52(0.999)|PRKN(0.998)|RPS27A(0.998)|UBC(0.998)|UBE2N(0.994)
UBC,ubiquitin C,ENSG00000150991,7316,P0CG48,Reactome,1,TRUE,Ubc,99.854,TRUE,Artery_Tibial,629.29,629.29,Low tissue specificity,Cell type enhanced,106,IKBKG(0.999)|PRKN(0.999)|SQSTM1(0.999)|UBA52(0.999)|UBE2N(0.999)
UBE2C,ubiquitin conjugating enzyme E2 C,ENSG00000175063,11065,O00762,CellAge|Reactome,2,TRUE,Ube2c,95.5307,TRUE,Cells_EBV-transformed_lymphocytes,144.45,144.45,Tissue enhanced,Cell type enhanced,73,ANAPC11(0.999)|ANAPC2(0.998)|CCNA2(0.994)|ANAPC10(0.993)|ANAPC4(0.993)
UBE2D1,ubiquitin conjugating enzyme E2 D1,ENSG00000072401,7321,P51668,Reactome,1,TRUE,Ube2d1,100,TRUE,Muscle_Skeletal,55.27,55.27,Tissue enhanced,Cell type enhanced,42,RBX1(0.999)|STUB1(0.999)|MDM2(0.997)|UBC(0.997)|RPS27A(0.993)
UBE2E1,ubiquitin conjugating enzyme E2 E1,ENSG00000170142,7324,P51965,Reactome,1,TRUE,Ube2e1,98.9637,FALSE,Cells_EBV-transformed_lymphocytes,145.74,145.74,Low tissue specificity,Low cell type specificity,27,NEDD4(0.904)|ANAPC4(0.888)|ANAPC11(0.868)|ANAPC10(0.863)|CDC16(0.851)
UBE2I,ubiquitin conjugating enzyme E2 I,ENSG00000103275,7329,P63279,CellAge|GenAge,2,TRUE,Ube2i,100,TRUE,Ovary,80.85,80.85,Low tissue specificity,Cell type enhanced,63,SUMO1(0.999)|SUMO2(0.999)|SUMO3(0.999)|TP53(0.994)|PML(0.981)
UBE2N,ubiquitin conjugating enzyme E2 N,ENSG00000177889,7334,P61088,CellAge,1,TRUE,Ube2n,100,TRUE,Testis,159.51,159.51,Low tissue specificity,Cell type enriched,41,RPS27A(0.999)|STUB1(0.999)|UBC(0.999)|UBE2V1(0.999)|UBE2V2(0.999)
UBE2S,ubiquitin conjugating enzyme E2 S,ENSG00000108106,27338,Q16763,Reactome,1,TRUE,Ube2s,92.7928,TRUE,Testis,132.58,132.58,Tissue enhanced,Cell type enhanced,55,ANAPC11(0.999)|CDC27(0.999)|ANAPC10(0.996)|ANAPC2(0.996)|UBC(0.996)
UBE2V1,ubiquitin conjugating enzyme E2 V1,ENSG00000244687,7335,Q13404,CellAge,1,TRUE,Ube2v1,65.9864,FALSE,Cells_Cultured_fibroblasts,109.6,109.6,Low tissue specificity,Cell type enhanced,19,UBE2N(0.999)|STUB1(0.996)|UBC(0.991)|RPS27A(0.99)|UBA52(0.975)
UBE2V2,ubiquitin conjugating enzyme E2 V2,ENSG00000169139,7336,Q15819,CellAge,1,TRUE,Ube2v2,98.6207,TRUE,Brain_Frontal_Cortex_BA9,37.65,37.65,Low tissue specificity,Cell type enhanced,23,UBC(0.999)|UBE2N(0.999)|RPS27A(0.997)|UBB(0.991)|UBA52(0.982)
UBE3A,ubiquitin protein ligase E3A,ENSG00000114062,7337,Q05086,CellAge,1,TRUE,Ube3a,93.8073,TRUE,Muscle_Skeletal,22.73,22.73,Low tissue specificity,Low cell type specificity,21,TP53(0.999)|UBE2D1(0.984)|CTNNB1(0.974)|PTEN(0.96)|MYC(0.935)
UBN1,ubinuclein 1,ENSG00000118900,29855,Q9NPG3,Reactome,1,TRUE,Ubn1,87.037,TRUE,Testis,64.03,64.03,Low tissue specificity,Cell type enhanced,4,ASF1A(0.999)|CABIN1(0.999)|HIRA(0.999)|OGT(0.734)
UBTD1,ubiquitin domain containing 1,ENSG00000165886,80019,Q9HAC8,CellAge,1,TRUE,Ubtd1,98.6784,TRUE,Testis,142.62,142.62,Low tissue specificity,Cell type enhanced,0,
UCHL1,ubiquitin C-terminal hydrolase L1,ENSG00000154277,7345,P09936,GenAge,1,TRUE,Uchl1,86.5471,TRUE,Brain_Frontal_Cortex_BA9,1197.45,1197.45,Group enriched,Cell type enriched,20,UBC(0.999)|RPS27A(0.991)|UBA52(0.982)|UBB(0.981)|PRKN(0.96)
UCP1,uncoupling protein 1,ENSG00000109424,7350,P25874,GenAge,1,TRUE,Ucp1,79.1531,TRUE,Testis,0.43,0.43,Tissue enhanced,Cell type enhanced,7,PPARGC1A(0.943)|PPARG(0.925)|PPARA(0.919)|LEP(0.874)|INS(0.868)
UCP2,uncoupling protein 2,ENSG00000175567,7351,P55851,GenAge,1,TRUE,Ucp2,96.1165,TRUE,Spleen,245.1,245.1,Tissue enhanced,Cell type enhanced,8,PPARGC1A(0.928)|LEP(0.885)|PPARG(0.859)|SREBF1(0.848)|PPARA(0.821)
UCP3,uncoupling protein 3,ENSG00000175564,7352,P55916,GenAge,1,TRUE,Ucp3,85.5769,FALSE,Muscle_Skeletal,145.52,145.52,Group enriched,Group enriched,4,PPARGC1A(0.917)|CPT1C(0.81)|PPARG(0.774)|PPARA(0.729)
UHRF1,ubiquitin like with PHD and ring finger domains 1,ENSG00000276043,29128,Q96T88,CellAge,1,TRUE,Uhrf1,73.5183,TRUE,Cells_EBV-transformed_lymphocytes,24.58,24.58,Group enriched,Cell type enhanced,29,DNMT1(0.999)|EHMT2(0.997)|H3-4(0.997)|HDAC1(0.996)|DNMT3B(0.985)
ULK3,unc-51 like kinase 3,ENSG00000140474,25989,Q6PHR2,CellAge,1,TRUE,Ulk3,94.0678,TRUE,Brain_Cerebellum,261.1,261.1,Low tissue specificity,Cell type enhanced,6,GLI1(0.84)|ATG5(0.813)|ATG12(0.795)|BECN1(0.72)|ATG16L1(0.718)
USP1,ubiquitin specific peptidase 1,ENSG00000162607,7398,O94782,CellAge,1,TRUE,Usp1,88.1529,TRUE,Testis,54.66,54.66,Low tissue specificity,Cell type enhanced,8,FANCD2(0.998)|UBC(0.989)|UBA52(0.963)|RPS27A(0.956)|UBB(0.953)
USP28,ubiquitin specific peptidase 28,ENSG00000048028,57646,Q96RU2,CellAge,1,TRUE,Usp28,83.0553,TRUE,Brain_Cerebellar_Hemisphere,33.76,33.76,Tissue enhanced,Cell type enhanced,10,TP53BP1(0.998)|UBC(0.991)|MYC(0.966)|UBA52(0.951)|RPS27A(0.932)
UTP6,UTP6 small subunit processome component,ENSG00000108651,55813,Q9NYH9,CellAge,1,TRUE,Utp6,86.0972,TRUE,Cells_EBV-transformed_lymphocytes,36.48,36.48,Low tissue specificity,Low cell type specificity,8,BMS1(0.999)|PDCD11(0.994)|RPS9(0.99)|RPS14(0.978)|PES1(0.825)
VCAN,versican,ENSG00000038427,1462,P13611,CellAge,1,TRUE,Vcan,62.7797,TRUE,Artery_Aorta,214,214,Tissue enhanced,Cell type enhanced,4,TLR2(0.923)|ELN(0.874)|SDC1(0.793)|MMP9(0.783)
VCP,valosin containing protein,ENSG00000165280,7415,P55072,GenAge,1,TRUE,Vcp,100,TRUE,Cells_Cultured_fibroblasts,229.15,229.15,Low tissue specificity,Cell type enhanced,39,SPRTN(0.976)|UBC(0.975)|HSPA5(0.944)|HSP90AA1(0.933)|PRKN(0.928)
VDR,vitamin D receptor,ENSG00000111424,7421,P11473,CellAge,1,TRUE,Vdr,88.0562,TRUE,Skin_Not_Sun_Exposed_Suprapubic,32.05,32.05,Tissue enriched,Cell type enhanced,0,
VEGFA,vascular endothelial growth factor A,ENSG00000112715,7422,P15692,CellAge|GenAge|SenMayo,3,TRUE,Vegfa,76.7089,TRUE,Thyroid,615.37,615.37,Low tissue specificity,Cell type enhanced,0,
VEGFC,vascular endothelial growth factor C,ENSG00000150630,7424,P49767,SenMayo,1,TRUE,Vegfc,85.4415,TRUE,Cells_Cultured_fibroblasts,56.68,56.68,Low tissue specificity,Cell type enhanced,20,FLT1(0.999)|KDR(0.999)|FGFR1(0.896)|PDGFRB(0.892)|PDGFRA(0.873)
VENTX,VENT homeobox,ENSG00000151650,27287,O95231,CellAge|Reactome,2,FALSE,,,TRUE,Nerve_Tibial,12.71,12.71,Low tissue specificity,Group enriched,2,TP53(0.77)|IL6(0.756)
VGF,VGF nerve growth factor inducible,ENSG00000128564,7425,O15240,SenMayo,1,TRUE,Vgf,86.6667,FALSE,Pituitary,138.27,138.27,Group enriched,Cell type enriched,3,EGR1(0.836)|BDNF(0.807)|NGF(0.715)
WEE1,WEE1 G2 checkpoint kinase,ENSG00000166483,7465,P30291,CellAge,1,TRUE,Wee1,90.4025,TRUE,Skin_Not_Sun_Exposed_Suprapubic,53.99,53.99,Low tissue specificity,Cell type enhanced,24,CDK1(0.998)|CHEK1(0.992)|PLK1(0.992)|CCNB1(0.99)|CDK2(0.987)
WIF1,Wnt inhibitory factor 1,ENSG00000156076,11197,Q9Y5W5,CellAge,1,TRUE,Wif1,93.9314,TRUE,Brain_Caudate_basal_ganglia,79.46,79.46,Tissue enriched,Cell type enriched,8,WNT5A(0.985)|WNT2(0.963)|WNT16(0.948)|WNT7B(0.947)|SFRP1(0.924)
WIPI1,"WD repeat domain, phosphoinositide interacting 1",ENSG00000070540,55062,Q5MNZ9,CellAge,1,TRUE,Wipi1,93.4978,TRUE,Cells_Cultured_fibroblasts,131.58,131.58,Tissue enhanced,Cell type enhanced,7,ATG16L1(0.99)|ATG12(0.96)|BECN1(0.926)|ATG5(0.906)|ATG7(0.859)
WNT16,Wnt family member 16,ENSG00000002745,51384,Q9UBV4,CellAge|SenMayo,2,TRUE,Wnt16,90.411,TRUE,Skin_Not_Sun_Exposed_Suprapubic,10.26,10.26,Group enriched,Cell type enhanced,7,WIF1(0.948)|GPC3(0.918)|SFRP1(0.906)|DKK1(0.879)|CTNNB1(0.785)
WNT2,Wnt family member 2,ENSG00000105989,7472,P09544,CellAge|SenMayo,2,TRUE,Wnt2,96.3889,TRUE,Lung,20.5,20.5,Tissue enriched,Group enriched,9,WIF1(0.963)|SFRP1(0.928)|GPC3(0.927)|DKK1(0.909)|CTNNB1(0.893)
WNT5A,Wnt family member 5A,ENSG00000114251,7474,P41221,CellAge,1,TRUE,Wnt5a,98.6842,TRUE,Cells_Cultured_fibroblasts,128.43,128.43,Tissue enhanced,Cell type enhanced,13,WIF1(0.985)|SFRP1(0.963)|GPC3(0.96)|DKK1(0.942)|CTNNB1(0.869)
WNT7B,Wnt family member 7B,ENSG00000188064,7477,P56706,CellAge,1,TRUE,Wnt7b,74.4986,TRUE,Skin_Not_Sun_Exposed_Suprapubic,22.38,22.38,Tissue enhanced,Cell type enhanced,5,SFRP1(0.963)|WIF1(0.947)|GPC3(0.919)|DKK1(0.876)|CTNNB1(0.746)
WRN,WRN RecQ like helicase,ENSG00000165392,7486,Q14191,CellAge|GenAge,2,TRUE,Wrn,69.5531,TRUE,Cells_EBV-transformed_lymphocytes,19.37,19.37,Low tissue specificity,Cell type enhanced,60,RPA1(0.999)|FEN1(0.998)|XRCC6(0.998)|RAD52(0.996)|TOP3A(0.996)
WSB1,WD repeat and SOCS box containing 1,ENSG00000109046,26118,Q9Y6I7,CellAge,1,TRUE,Wsb1,92.6366,TRUE,Cervix_Ectocervix,268,268,Low tissue specificity,Low cell type specificity,3,RBX1(0.808)|HIPK2(0.757)|NF1(0.725)
WT1,WT1 transcription factor,ENSG00000184937,7490,P19544,CellAge,1,TRUE,Wt1,92.1456,TRUE,Uterus,109.72,109.72,Tissue enhanced,Cell type enhanced,13,TP53(0.983)|GATA4(0.935)|EWSR1(0.888)|EZH2(0.824)|IGF2(0.812)
WWP1,WW domain containing E3 ubiquitin protein ligase 1,ENSG00000123124,11059,Q9H0M0,CellAge,1,TRUE,Wwp1,90.4555,TRUE,Muscle_Skeletal,55.45,55.45,Tissue enhanced,Cell type enhanced,12,UBC(0.986)|UBA52(0.974)|UBB(0.973)|SMAD3(0.901)|SMAD6(0.848)
XAF1,XIAP associated factor 1,ENSG00000132530,54739,Q6GPH4,CellAge,1,TRUE,Xaf1,44.8505,TRUE,Ovary,45.95,45.95,Low tissue specificity,Cell type enhanced,6,XIAP(0.999)|STAT1(0.931)|IRF7(0.906)|EIF2AK2(0.897)|IRF1(0.787)
XIAP,X-linked inhibitor of apoptosis,ENSG00000101966,331,P98170,CellAge,1,TRUE,Xiap,89.336,TRUE,Brain_Cerebellar_Hemisphere,18.26,18.26,Low tissue specificity,Low cell type specificity,34,HTRA2(0.999)|XAF1(0.999)|BIRC5(0.96)|BCL2(0.951)|MAP3K7(0.951)
XPA,"XPA, DNA damage recognition and repair factor",ENSG00000136936,7507,P23025,GenAge,1,TRUE,Xpa,84.9817,TRUE,Thyroid,50.22,50.22,Low tissue specificity,Low cell type specificity,43,ERCC1(0.999)|ERCC2(0.999)|ERCC3(0.999)|ERCC4(0.999)|RAD23B(0.997)
XPC,"XPC complex subunit, DNA damage recognition and repair factor",ENSG00000154767,7508,Q01831,CellAge,1,TRUE,Xpc,74.3617,TRUE,Cells_Cultured_fibroblasts,82.01,82.01,Low tissue specificity,Low cell type specificity,30,RAD23B(0.999)|ERCC1(0.994)|ERCC4(0.983)|DDB2(0.982)|XPA(0.981)
XPO1,exportin 1,ENSG00000082898,7514,O14980,CellAge,1,TRUE,Xpo1,98.0392,TRUE,Cells_EBV-transformed_lymphocytes,99.38,99.38,Low tissue specificity,Low cell type specificity,25,RAN(0.999)|CDKN1B(0.97)|TP53(0.959)|CCNB1(0.931)|RCC1(0.927)
XRCC5,X-ray repair cross complementing 5,ENSG00000079246,7520,P13010,GenAge,1,TRUE,Xrcc5,78.4153,TRUE,Cells_EBV-transformed_lymphocytes,292,292,Low tissue specificity,Low cell type specificity,65,NHEJ1(0.999)|PRKDC(0.999)|XRCC6(0.999)|ATM(0.998)|PARP1(0.996)
XRCC6,X-ray repair cross complementing 6,ENSG00000196419,2547,P12956,GenAge,1,TRUE,Xrcc6,83.087,TRUE,Testis,405.75,405.75,Low tissue specificity,Cell type enhanced,82,NHEJ1(0.999)|PRKDC(0.999)|XRCC5(0.999)|PARP1(0.998)|WRN(0.998)
YAP1,Yes1 associated transcriptional regulator,ENSG00000137693,10413,P46937,CellAge,1,TRUE,Yap1,85.7143,TRUE,Artery_Aorta,189.67,189.67,Low tissue specificity,Low cell type specificity,42,LATS1(0.999)|LATS2(0.999)|TEAD1(0.999)|TEAD4(0.999)|CTNNB1(0.997)
YBX1,Y-box binding protein 1,ENSG00000065978,4904,P67809,CellAge,1,TRUE,Ybx1,98.4568,TRUE,Testis,1311.63,1311.63,Tissue enhanced,Cell type enhanced,34,DHX9(0.994)|HSPA1B(0.991)|HSPA1A(0.985)|MECP2(0.978)|EWSR1(0.943)
YEATS4,YEATS domain containing 4,ENSG00000127337,8089,O95619,CellAge,1,TRUE,Yeats4,99.5595,TRUE,Testis,51.33,51.33,Low tissue specificity,Cell type enhanced,17,EP400(0.999)|KAT5(0.999)|MORF4L1(0.999)|RUVBL2(0.998)|TRRAP(0.997)
YPEL3,yippee like 3,ENSG00000090238,83719,P61236,CellAge,1,TRUE,Ypel3,75.7962,TRUE,Whole_Blood,280.15,280.15,Low tissue specificity,Cell type enhanced,0,
YWHAB,tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta,ENSG00000166913,7529,P31946,CellAge,1,TRUE,Ywhab,98.7805,TRUE,Brain_Frontal_Cortex_BA9,301.13,301.13,Low tissue specificity,Cell type enhanced,34,RAF1(0.998)|BRAF(0.994)|YWHAZ(0.992)|YAP1(0.983)|FOXO3(0.969)
YWHAZ,tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta,ENSG00000164924,7534,P63104,CellAge|GenAge,2,TRUE,Ywhaz,99.5918,FALSE,Esophagus_Mucosa,385.92,385.92,Low tissue specificity,Cell type enhanced,44,BRAF(0.999)|RAF1(0.999)|FOXO3(0.994)|CTNNB1(0.993)|YWHAB(0.992)
YY1,YY1 transcription factor,ENSG00000100811,7528,P25490,CellAge,1,TRUE,Yy1,98.7923,TRUE,Thyroid,55.44,55.44,Low tissue specificity,Low cell type specificity,69,EP300(0.999)|HDAC1(0.999)|HDAC2(0.999)|EZH2(0.998)|PPARGC1A(0.995)
ZCCHC10,zinc finger CCHC-type containing 10,ENSG00000155329,54819,Q8TBK6,CellAge,1,TRUE,Zcchc10,77.0833,TRUE,Cells_EBV-transformed_lymphocytes,22.6,22.6,Low tissue specificity,Cell type enhanced,0,
ZDHHC3,zDHHC palmitoyltransferase 3,ENSG00000163812,51304,Q9NYG2,CellAge,1,TRUE,Zdhhc3,97.3244,TRUE,Testis,68.76,68.76,Low tissue specificity,Group enriched,0,
ZEB1,zinc finger E-box binding homeobox 1,ENSG00000148516,6935,P37275,CellAge,1,TRUE,Zeb1,86.2222,TRUE,Colon_Sigmoid,79.78,79.78,Low tissue specificity,Cell type enhanced,28,HDAC1(0.975)|SMARCA4(0.962)|CDH1(0.961)|SMAD3(0.95)|EP300(0.932)
ZFP36,ZFP36 zinc finger CCCH-type,ENSG00000128016,7538,P26651,CellAge,1,TRUE,Zfp36,84.0491,TRUE,Adipose_Visceral_Omentum,1841.53,1841.53,Low tissue specificity,Cell type enhanced,15,MAPKAPK2(0.979)|DUSP1(0.934)|AGO2(0.914)|TNF(0.912)|YWHAB(0.895)
ZFX,zinc finger protein X-linked,ENSG00000005889,7543,P17010,CellAge,1,TRUE,Zfx,95.0311,FALSE,Uterus,24.57,24.57,Low tissue specificity,Cell type enhanced,3,MYCN(0.88)|MYC(0.784)|E2F1(0.725)
ZMAT3,zinc finger matrin-type 3,ENSG00000172667,64393,Q9HA38,CellAge,1,TRUE,Zmat3,86.8512,TRUE,Cells_EBV-transformed_lymphocytes,49.72,49.72,Low tissue specificity,Cell type enhanced,1,TP53(0.708)
ZMPSTE24,zinc metallopeptidase STE24,ENSG00000084073,10269,O75844,CellAge|GenAge,2,TRUE,Zmpste24,93.4737,TRUE,Artery_Aorta,70.8,70.8,Low tissue specificity,Low cell type specificity,7,FNTB(0.963)|LMNA(0.961)|BSCL2(0.803)|AGPAT2(0.801)|SUN1(0.795)
ZMYND11,zinc finger MYND-type containing 11,ENSG00000015171,10771,Q15326,CellAge,1,TRUE,Zmynd11,97.6744,TRUE,Brain_Cerebellar_Hemisphere,97.83,97.83,Low tissue specificity,Low cell type specificity,1,H3-4(0.745)
ZNF148,zinc finger protein 148,ENSG00000163848,7707,Q9UQR1,CellAge,1,TRUE,Zfp148,97.6071,TRUE,Thyroid,16.37,16.37,Low tissue specificity,Cell type enhanced,3,TP53(0.857)|EP300(0.784)|HDAC1(0.739)
ZNF207,zinc finger protein 207,ENSG00000010244,7756,O43670,CellAge,1,TRUE,Zfp207,92.7125,TRUE,Cells_EBV-transformed_lymphocytes,54.53,54.53,Low tissue specificity,Low cell type specificity,2,BUB3(0.997)|SRSF3(0.741)
ZNF217,zinc finger protein 217,ENSG00000171940,7764,O75362,CellAge,1,TRUE,Zfp217,70.0382,TRUE,Cells_EBV-transformed_lymphocytes,48.7,48.7,Low tissue specificity,Cell type enhanced,5,HDAC2(0.989)|HDAC1(0.987)|KDM1A(0.986)|KDM5B(0.76)|ESR1(0.714)