node1,node2,combined_score
AKT1,SIRT1,0.873
AKT1,NFKBIA,0.849
AKT1,CCND1,0.923
AKT1,IFNG,0.817
AKT1,KDR,0.715
AKT1,STAT3,0.966
AKT1,TP53,0.994
AKT1,PPARG,0.79
AKT1,RICTOR,0.992
AKT1,IRS1,0.972
AKT1,SOX2,0.833
AKT1,FOXO3,0.998
AKT1,MAP2K3,0.862
AKT1,E2F1,0.797
AKT1,ATG7,0.735
AKT1,MAP3K5,0.985
AKT1,DNMT1,0.822
AKT1,MTOR,0.999
AKT1,PTGS2,0.775
AKT1,MCL1,0.867
AKT1,CHUK,0.996
AKT1,PTEN,0.988
AKT1,CCND3,0.761
AKT1,TLR4,0.769
AKT1,BCL2,0.993
AKT1,CDKN1A,0.995
AKT1,RAF1,0.992
AKT1,WEE1,0.794
AKT1,BDNF,0.835
AKT1,BRCA1,0.993
AKT1,PIK3R1,0.995
AKT1,HIF1A,0.932
AKT1,MYC,0.928
AKT1,AKT3,0.958
AKT3,TP53,0.953
AKT3,RICTOR,0.793
AKT3,FOXO3,0.966
AKT3,MAP3K5,0.911
AKT3,MTOR,0.96
AKT3,CHUK,0.916
AKT3,PTEN,0.825
AKT3,BCL2,0.947
AKT3,CDKN1A,0.95
AKT3,RAF1,0.922
AKT3,BRCA1,0.934
AKT3,PIK3R1,0.977
APP,STAT3,0.753
APP,TP53,0.714
APP,MAP3K5,0.728
APP,FOXO3,0.836
APP,BDNF,0.858
ATG16L1,ATG7,0.995
ATG7,SIRT1,0.993
ATG7,TP53,0.907
ATG7,FOXO3,0.79
ATG7,MTOR,0.772
ATG7,BCL2,0.807
BCL2,SIRT1,0.744
BCL2,NFKBIA,0.73
BCL2,CCND1,0.958
BCL2,IFNG,0.795
BCL2,STAT3,0.959
BCL2,CDK6,0.712
BCL2,TP53,0.999
BCL2,IRS1,0.785
BCL2,FOXO3,0.73
BCL2,E2F1,0.778
BCL2,MAP3K5,0.755
BCL2,MTOR,0.765
BCL2,PTGS2,0.745
BCL2,MCL1,0.764
BCL2,CHUK,0.813
BCL2,PTEN,0.815
BCL2,TLR4,0.724
BCL2,BMI1,0.723
BCL2,IGF1R,0.781
BCL2,BDNF,0.793
BCL2,BRCA1,0.8
BCL2,CDKN1A,0.82
BCL2,RAF1,0.892
BCL2,HIF1A,0.946
BCL2,MYC,0.955
BDNF,KDR,0.795
BDNF,FGFR1,0.864
BDNF,IGF1R,0.907
BIRC5,CCND1,0.751
BIRC5,STAT3,0.796
BIRC5,TP53,0.93
BIRC5,CHEK1,0.815
BIRC5,MYC,0.825
BIRC5,UBE2C,0.992
BMI1,TP53,0.956
BMI1,RUNX1,0.875
BMI1,SOX2,0.825
BMI1,UBE2C,0.91
BMI1,DNMT1,0.791
BMI1,PTEN,0.761
BMI1,MYC,0.878
BMI1,BRCA1,0.97
BMPR2,LIMK1,0.989
BRCA1,SIRT1,0.777
BRCA1,CCND1,0.922
BRCA1,STAT3,0.812
BRCA1,RB1,0.858
BRCA1,TP53,0.999
BRCA1,RICTOR,0.702
BRCA1,PGR,0.963
BRCA1,FOXO3,0.749
BRCA1,E2F1,0.879
BRCA1,UBE2C,0.951
BRCA1,DNMT1,0.799
BRCA1,PTEN,0.821
BRCA1,CDKN1A,0.809
BRCA1,CHEK1,0.996
BRCA1,PIK3R1,0.766
BRCA1,MYC,0.999
CCND1,SIRT1,0.721
CCND1,RUNX1,0.733
CCND1,FOXO3,0.756
CCND1,SOX2,0.792
CCND1,MTOR,0.802
CCND1,PGR,0.834
CCND1,MCL1,0.837
CCND1,PTEN,0.855
CCND1,HIF1A,0.876
CCND1,RBL1,0.935
CCND1,E2F1,0.938
CCND1,CCND3,0.939
CCND1,TP53,0.946
CCND1,RBL2,0.966
CCND1,MYC,0.969
CCND1,STAT3,0.98
CCND1,FBXO31,0.985
CCND1,RB1,0.998
CCND1,CDK6,0.999
CCND1,CDKN1A,0.999
CCND3,RBL2,0.995
CCND3,CDK6,0.999
CCND3,RB1,0.989
CCND3,RUNX1,0.811
CCND3,E2F1,0.777
CCND3,RBL1,0.927
CCND3,CDKN1A,0.999
CDK6,RBL2,0.974
CDK6,STAT3,0.881
CDK6,HMGA2,0.704
CDK6,MYC,0.788
CDK6,PTEN,0.801
CDK6,FOXO3,0.802
CDK6,TP53,0.808
CDK6,WEE1,0.828
CDK6,RUNX1,0.929
CDK6,E2F1,0.931
CDK6,RBL1,0.942
CDK6,RB1,0.997
CDK6,CDKN1A,0.999
CDKN1A,SIRT1,0.719
CDKN1A,RBL2,0.959
CDKN1A,STAT3,0.984
CDKN1A,RB1,0.876
CDKN1A,TP53,0.999
CDKN1A,FOXO3,0.995
CDKN1A,E2F1,0.977
CDKN1A,MAP3K5,0.97
CDKN1A,MCL1,0.849
CDKN1A,PTEN,0.792
CDKN1A,WEE1,0.709
CDKN1A,CHEK1,0.74
CDKN1A,MYC,0.981
CHEK1,TP53,0.997
CHEK1,PPM1D,0.775
CHEK1,E2F1,0.764
CHEK1,DNMT1,0.711
CHEK1,MTOR,0.763
CHEK1,PTEN,0.791
CHEK1,MYC,0.76
CHEK1,WEE1,0.992
CHUK,NFKBIA,0.999
CHUK,TP53,0.914
CHUK,IRS1,0.953
CHUK,FOXO3,0.957
CHUK,MTOR,0.973
CHUK,TLR4,0.852
CHUK,MYC,0.879
CHUK,PTEN,0.964
DNMT1,SIRT1,0.922
DNMT1,RBL2,0.823
DNMT1,STAT3,0.957
DNMT1,RB1,0.765
DNMT1,TP53,0.997
DNMT1,RUNX1,0.743
DNMT1,E2F1,0.964
DNMT1,MYC,0.837
E2F1,SIRT1,0.924
E2F1,RBL2,0.991
E2F1,STAT3,0.797
E2F1,RB1,0.999
E2F1,TP53,0.986
E2F1,FOXO3,0.994
E2F1,PTEN,0.839
E2F1,RBL1,0.994
E2F1,MYC,0.995
EPAS1,MTOR,0.728
EPAS1,TP53,0.736
EPAS1,SOX2,0.874
EPAS1,MYC,0.932
EPAS1,HIF1A,0.998
FGFR1,IRS1,0.834
FGFR1,PIK3R1,0.992
FOXO3,SIRT1,0.999
FOXO3,STAT3,0.978
FOXO3,TP53,0.998
FOXO3,RICTOR,0.83
FOXO3,RUNX1,0.908
FOXO3,MCL1,0.705
FOXO3,MTOR,0.747
FOXO3,PTEN,0.853
FOXO3,MYC,0.874
FOXO3,HIF1A,0.997
HIF1A,SIRT1,0.927
HIF1A,NFKBIA,0.735
HIF1A,KDR,0.785
HIF1A,STAT3,0.994
HIF1A,TP53,0.999
HIF1A,PPARG,0.854
HIF1A,RUNX1,0.945
HIF1A,SOX2,0.758
HIF1A,PGR,0.717
HIF1A,MTOR,0.789
HIF1A,PTGS2,0.831
HIF1A,MCL1,0.825
HIF1A,PTEN,0.83
HIF1A,IGF1R,0.752
HIF1A,MYC,0.993
HMGA1,TP53,0.72
HMGA1,PPARG,0.733
HMGA1,HMGA2,0.902
HMGA2,TP53,0.867
HMGA2,MYC,0.756
IFNG,NFKBIA,0.714
IFNG,PTGS2,0.816
IFNG,TP53,0.834
IFNG,RUNX1,0.893
IFNG,STAT3,0.907
IFNG,TLR4,0.946
IGF1R,IGFBP2,0.81
IGF1R,STAT3,0.921
IGF1R,TP53,0.853
IGF1R,IRS1,0.999
IGF1R,PGR,0.82
IGF1R,MTOR,0.872
IGF1R,PTEN,0.88
IGF1R,PIK3R1,0.994
IGF1R,MYC,0.712
IRS1,SIRT1,0.823
IRS1,KDR,0.743
IRS1,STAT3,0.734
IRS1,TP53,0.702
IRS1,PPARG,0.726
IRS1,RICTOR,0.777
IRS1,PTEN,0.792
IRS1,MTOR,0.992
IRS1,PIK3R1,0.999
KDR,MYC,0.723
KDR,TP53,0.73
KDR,PIK3R1,0.943
MAP2K3,TP53,0.711
MAP2K3,MYC,0.743
MAP2K3,MAP3K5,0.988
MAP3K5,STAT3,0.807
MCL1,STAT3,0.883
MCL1,TP53,0.918
MCL1,PTEN,0.763
MCL1,MYC,0.857
MMP7,TP53,0.774
MTOR,SIRT1,0.937
MTOR,STAT3,0.926
MTOR,TP53,0.874
MTOR,PPARG,0.964
MTOR,RICTOR,0.999
MTOR,MYC,0.73
MTOR,PTEN,0.942
MTOR,PIK3R1,0.956
MYC,SIRT1,0.86
MYC,STAT3,0.985
MYC,RB1,0.888
MYC,TP53,0.997
MYC,RICTOR,0.708
MYC,SOX2,0.958
MYC,PGR,0.705
MYC,PTGS2,0.715
MYC,PTEN,0.908
MYC,PIM1,0.796
MYC,NCOR2,0.818
MYC,RAF1,0.755
NCOR2,SIRT1,0.7
NCOR2,PPARG,0.999
NCOR2,RUNX1,0.815
NCOR2,PGR,0.992
NFKBIA,STAT3,0.741
NFKBIA,PIK3R1,0.773
NFKBIA,PTGS2,0.856
NFKBIA,TLR4,0.872
NFKBIA,TP53,0.915
PDCD4,RECK,0.793
PDCD4,PTEN,0.805
PGR,STAT3,0.858
PGR,RB1,0.782
PGR,TP53,0.849
PGR,PIK3R1,0.931
PIK3R1,STAT3,0.918
PIK3R1,TP53,0.853
PIK3R1,TGFBR2,0.772
PIK3R1,PTEN,0.997
PIK3R1,TLR4,0.925
PIK3R1,RAF1,0.944
PIM1,STAT3,0.733
PPARG,SIRT1,0.998
PPARG,STAT3,0.826
PPARG,TP53,0.949
PPARG,PTGS2,0.735
PPARG,TLR4,0.738
PPARG,PTEN,0.83
PPM1D,TP53,0.883
PTEN,SIRT1,0.757
PTEN,STAT3,0.794
PTEN,RB1,0.734
PTEN,TP53,0.999
PTEN,RICTOR,0.834
PTEN,SOX2,0.743
PTGS2,STAT3,0.93
PTGS2,TP53,0.974
PTGS2,TLR4,0.787
RAF1,STAT3,0.762
RAF1,RB1,0.824
RB1,SIRT1,0.821
RB1,RBL2,0.949
RB1,RBL1,0.923
RB1,TP53,0.936
RBL1,RBL2,0.969
RBL2,TP53,0.76
RECK,SPARC,0.761
RICTOR,SIRT1,0.732
RUNX1,STAT3,0.726
RUNX1,TP53,0.82
RUNX1,YAP1,0.936
SIRT1,STAT3,0.817
SIRT1,TP53,0.999
SOX2,STAT3,0.903
SOX2,TP53,0.883
SOX2,YAP1,0.702
STAT3,YAP1,0.818
STAT3,TLR4,0.846
STAT3,TP53,0.994
TGFBR2,YAP1,0.932
TP53,YAP1,0.721
TP53,WEE1,0.753
TP53,TP53INP1,0.935