LINF_310010800

Wikidata: Q106152499

Protein name: ATP-binding cassette protein subfamily D, member 2 | ABCD2 | Glycosomal ABC Transporter 1 (GAT1)
Nombre de la proteina: Miembro 2 de la subfamilia D de proteinas ABC | ABCD2 | Transportador ABC glicosomal | GAT1
Organism/Organismo: Leishmania infantum (JPCM5)

Reference: 	Gonzalez-de la Fuente, S., Peiro-Pastor, R., Rastrojo, A., Moreno, J., Carrasco-Ramiro, F., Requena, J.M., and Aguado, B. (2017). Resequencing of the Leishmania infantum (strain JPCM5) genome and de novo assembly into 36 contigs. Sci Rep 7, 18050. https://rdcu.be/b6dQG



>Gene sequence
ccacacccacttacacgcatagaagcggctcacacgttggactcacgaaattcgagggcggcgcatcaacacgtgccacagatgcgtagtcatatccctgttttacttcacccctttcgcttttaatctttttcatttttgaagcttgccttcgagaagATGGTCTCCTCTGAGGTGCTCGGTGAGTACGTGAGGGAGTACGCGGCGTCGCGGTTGCGGGACCCCGTCATGGCCAGCTGGGTGGGTGGCTCCCTCGCCTTTCTCGCGACCATGTACGCTACGTCAAGCGGACGGCAGCTCGCCAAGGCAATGCCACCGCCACCGTTGCGAGGCATTCAGGGCAGTATCGTGCGCGGCACTGCCGCGTCTGAGGTGCGAAAGGGGGGCGGCCTCACACTCGTGCCGCAATCGACGCCTCTGTCGCCGTCCTCTCCGGTGTCGCGCGCGACTACGTCCTCCGTTTTCATCTCTGCCTCCGCGGCGACCGCAGAGGCTTACAGCCAAGTCTTCAACCAGGAGGTGTCTGTGTTCAATCGCTTTATGCAGCTGCTGCGTGTGGCGATCCCCAACTGCCATGGGCGGGAGGCGCGGAGCATCTACATTCTCTTTGTGCTGATGATTGTGCGTGCCTACGTGTCGGTGCGCCTTGTGAATGTCAGCGGGTTGGTCAGCCGCACGGCAATCGAGGGCAACCTGCGACACGCCATCCGTGCACTGGCGTTATTTGCCGTCTCGTGTGTGCCGGCCACTCTGCTGAACGTGACGCTCGACTACTACTCGGAGCTGCTGGGACTGCACTGCCGCGACAACCTCGCCGCCTACTTCTCCGACCGTTACCTGAAGCGGCGCGTCTTCTTCCAGATGGCCGGTCTGCACGAGGTGGACCACGTGGACCAGCGCATTACCGAGGACGTGCGTAACTGGGCGCGTGTGTCGGCTTCTCTCTTCACCAGCATTCCGCGTCCGCTGATCGAGGCCATCACCTTCTCCTTCACATTGGCGCGGCAGACGGGGTGGAGGGGGACGCTGTTGACGTGGTCCTACTACCTGACCTTTGCTGTGTGGATATGCTGCTGCGCCCCCAACCTTGACTGGATGGTGCAGCAGCGCACGGAGAAGGAGGGTGCGGTGCGGAGAGCACACCAGAGATTGCTGGCCTACGCGGAGGAGATCACGCTCACGAAGGGGTTTCAGTTCCACGAGAAAGTGCTGCAGCGCCTCTTCAAGGCAGTTACGGACCAGTCGCGCTACGCCGCCTACGTGCGGTCGCGCTTCGACTTCACTGAGACCTTGCACAACAAGTACGGATCAGTGTTGCTGGGCTACGTTGTGTGTGCCATGGCTACCATGCATCAGAAGAACCAGACGACAACCGCCGAGACGGCAACCGCAGCGCTGACGTGTGCCTCGTACACCTTCAAGACACTCGCCACCGCGATTGGGAAGTCTCTGTGGAACGTCAAGCTGGTGTTCGTCGTTGGCGGCTACACACGCCGACTGGCGCAGTTGCTTGCCGCGCTAGACCGCGCAGACGTGCTGGTAGAGATGCAGACGAGTTGCACCGCACAGTCCCCAATTGTGAGCCGCGCCTCTGGTGCCTTTCCGGTGCGCGGCAATGACGGGAAGGCCATGTCCAACTACGAGGACTCTTTCGGCCGCATCGTGCGCAGCGACCACATTGAGTTCGTCGACGTTCCGCTTGTGCTGCCCACCGGTGAGTGCCTCTGCAGCTCCATGTCATTTTACGTCAAGCCAGGAATGAACCTGCTCATTCTTGGTCGCAATGGGTGCGGCAAGTCCTCCACGTTTCGCCTTCTGGGTGAGCTGTGGCCACTGCGGGGTGGCCGTATCGAGAAGCCGGAGGCGGAGCAGCTGTACTACGTTCCGCAGCGGCCGTACATGTACGATGGCACGCTCCTCGAGCAGGTCATCTATCCCCTCAAGAAGAAGGACCTCACTGTCGGCGAGGCCGAGCTGTACGGCTACCTGCAGATGGCGGGGCTGGACTACGTTTTCAGCAAGTTGAACATGTCGTGGGAGACGCGGCTGCCGTGGAGCGACGACTCCCTCTCGCTTGGCGAGCAGCAGCGTCTTGCCATGGCCCGCCTCTTCTTTCACCGTCCGCGTTTTGCCATTCTCGACGAGTGCAGCAGTCTTGTCGACCTCGACGTGGAACGGCAGATGTACGACCGCTGCGTCGAGCTCGGCATCACTGTCATCACGATTGCGCACCGCCGCAGCGTGTGGCAGTACCACAACTGGATTCTCTACTTTGATGGCAGCGGTGGCTACATGTTCTCACCCCTGCAGTACGAGACGGGTGCCTCGGCGTTGGTGCTGACGTGCGTGCGATCCGCCTCGGATGCGTCGCTGATCGGCACGGAGGTGCGCATTCCTATCACGGACCGCCTATGCAGCGAGGATGAGACGGTGACGGCAAAGAAGGAGCCGCCGCCGAAGCTCATTCAAACAGCACAGAAGGCAGAGGTACCGAAGTCACCGAGGGCAGAGACGGTCACAGAGAAGGTAGAGAGAGAAGAGAGGGCAAAGGCAAACGGAGACGGCGATGGTGTGCATGGGTCACACAGGCAGTCGCGACACAGGCGCTCGCGCAAACACCGCGCCTCAGACGGCAACAAGGCAGTTGGTTTCGAGACCCAAGCGGAGACTAGCGGAGGAGAATAGttaaactttcgggtttcttgtttcgtgagcaccgtgttttgatgaggaagcaatgcgcataatgttgaggaggtgcggagagcagctgactaaaaggatgtctgaggagaggaacggcggacagaggggagcattacaacaccattttttttttcgtacgtcgtgtgggtaccgccagctacgccaaagtcgcgaagaagccctcctgccgctccttctactctcgatcggtaacggttccttcatagaggccttccattcttcccttcctctaccttaggaggcggcgcctccgtttcagcactcgtgtgtgcgtgtttgtatatgtgagggggggggtgcgtatgtgcggtgcaagagggcgctgctacctttgggctctgcttcatgcctgcctctctccctgtgttgtgcgctcttttccttttgcgcccccatgcttttccctctctctcgctgtcatgttgtgggtccccgaacgtgggtgctcgttccttgggttttgtacatgtgaatctctttttttctccaacctcttcctcctcctcgttcccccctttgtcaacgagcgagggcgtttgcgtctacgtgtgcacgcctttgcccacgtgcgaccatgcgcacagcgctagagagtgctcgcgtgcacacgtccttccgtagagcgttccgcggagggtgctgaattcgtttgatttgtcgtcccctgattccagccgattgt

>CDS sequence
ATGGTCTCCTCTGAGGTGCTCGGTGAGTACGTGAGGGAGTACGCGGCGTCGCGGTTGCGGGACCCCGTCATGGCCAGCTGGGTGGGTGGCTCCCTCGCCTTTCTCGCGACCATGTACGCTACGTCAAGCGGACGGCAGCTCGCCAAGGCAATGCCACCGCCACCGTTGCGAGGCATTCAGGGCAGTATCGTGCGCGGCACTGCCGCGTCTGAGGTGCGAAAGGGGGGCGGCCTCACACTCGTGCCGCAATCGACGCCTCTGTCGCCGTCCTCTCCGGTGTCGCGCGCGACTACGTCCTCCGTTTTCATCTCTGCCTCCGCGGCGACCGCAGAGGCTTACAGCCAAGTCTTCAACCAGGAGGTGTCTGTGTTCAATCGCTTTATGCAGCTGCTGCGTGTGGCGATCCCCAACTGCCATGGGCGGGAGGCGCGGAGCATCTACATTCTCTTTGTGCTGATGATTGTGCGTGCCTACGTGTCGGTGCGCCTTGTGAATGTCAGCGGGTTGGTCAGCCGCACGGCAATCGAGGGCAACCTGCGACACGCCATCCGTGCACTGGCGTTATTTGCCGTCTCGTGTGTGCCGGCCACTCTGCTGAACGTGACGCTCGACTACTACTCGGAGCTGCTGGGACTGCACTGCCGCGACAACCTCGCCGCCTACTTCTCCGACCGTTACCTGAAGCGGCGCGTCTTCTTCCAGATGGCCGGTCTGCACGAGGTGGACCACGTGGACCAGCGCATTACCGAGGACGTGCGTAACTGGGCGCGTGTGTCGGCTTCTCTCTTCACCAGCATTCCGCGTCCGCTGATCGAGGCCATCACCTTCTCCTTCACATTGGCGCGGCAGACGGGGTGGAGGGGGACGCTGTTGACGTGGTCCTACTACCTGACCTTTGCTGTGTGGATATGCTGCTGCGCCCCCAACCTTGACTGGATGGTGCAGCAGCGCACGGAGAAGGAGGGTGCGGTGCGGAGAGCACACCAGAGATTGCTGGCCTACGCGGAGGAGATCACGCTCACGAAGGGGTTTCAGTTCCACGAGAAAGTGCTGCAGCGCCTCTTCAAGGCAGTTACGGACCAGTCGCGCTACGCCGCCTACGTGCGGTCGCGCTTCGACTTCACTGAGACCTTGCACAACAAGTACGGATCAGTGTTGCTGGGCTACGTTGTGTGTGCCATGGCTACCATGCATCAGAAGAACCAGACGACAACCGCCGAGACGGCAACCGCAGCGCTGACGTGTGCCTCGTACACCTTCAAGACACTCGCCACCGCGATTGGGAAGTCTCTGTGGAACGTCAAGCTGGTGTTCGTCGTTGGCGGCTACACACGCCGACTGGCGCAGTTGCTTGCCGCGCTAGACCGCGCAGACGTGCTGGTAGAGATGCAGACGAGTTGCACCGCACAGTCCCCAATTGTGAGCCGCGCCTCTGGTGCCTTTCCGGTGCGCGGCAATGACGGGAAGGCCATGTCCAACTACGAGGACTCTTTCGGCCGCATCGTGCGCAGCGACCACATTGAGTTCGTCGACGTTCCGCTTGTGCTGCCCACCGGTGAGTGCCTCTGCAGCTCCATGTCATTTTACGTCAAGCCAGGAATGAACCTGCTCATTCTTGGTCGCAATGGGTGCGGCAAGTCCTCCACGTTTCGCCTTCTGGGTGAGCTGTGGCCACTGCGGGGTGGCCGTATCGAGAAGCCGGAGGCGGAGCAGCTGTACTACGTTCCGCAGCGGCCGTACATGTACGATGGCACGCTCCTCGAGCAGGTCATCTATCCCCTCAAGAAGAAGGACCTCACTGTCGGCGAGGCCGAGCTGTACGGCTACCTGCAGATGGCGGGGCTGGACTACGTTTTCAGCAAGTTGAACATGTCGTGGGAGACGCGGCTGCCGTGGAGCGACGACTCCCTCTCGCTTGGCGAGCAGCAGCGTCTTGCCATGGCCCGCCTCTTCTTTCACCGTCCGCGTTTTGCCATTCTCGACGAGTGCAGCAGTCTTGTCGACCTCGACGTGGAACGGCAGATGTACGACCGCTGCGTCGAGCTCGGCATCACTGTCATCACGATTGCGCACCGCCGCAGCGTGTGGCAGTACCACAACTGGATTCTCTACTTTGATGGCAGCGGTGGCTACATGTTCTCACCCCTGCAGTACGAGACGGGTGCCTCGGCGTTGGTGCTGACGTGCGTGCGATCCGCCTCGGATGCGTCGCTGATCGGCACGGAGGTGCGCATTCCTATCACGGACCGCCTATGCAGCGAGGATGAGACGGTGACGGCAAAGAAGGAGCCGCCGCCGAAGCTCATTCAAACAGCACAGAAGGCAGAGGTACCGAAGTCACCGAGGGCAGAGACGGTCACAGAGAAGGTAGAGAGAGAAGAGAGGGCAAAGGCAAACGGAGACGGCGATGGTGTGCATGGGTCACACAGGCAGTCGCGACACAGGCGCTCGCGCAAACACCGCGCCTCAGACGGCAACAAGGCAGTTGGTTTCGAGACCCAAGCGGAGACTAGCGGAGGAGAATAG

>Protein sequence
MVSSEVLGEYVREYAASRLRDPVMASWVGGSLAFLATMYATSSGRQLAKAMPPPPLRGIQGSIVRGTAASEVRKGGGLTLVPQSTPLSPSSPVSRATTSSVFISASAATAEAYSQVFNQEVSVFNRFMQLLRVAIPNCHGREARSIYILFVLMIVRAYVSVRLVNVSGLVSRTAIEGNLRHAIRALALFAVSCVPATLLNVTLDYYSELLGLHCRDNLAAYFSDRYLKRRVFFQMAGLHEVDHVDQRITEDVRNWARVSASLFTSIPRPLIEAITFSFTLARQTGWRGTLLTWSYYLTFAVWICCCAPNLDWMVQQRTEKEGAVRRAHQRLLAYAEEITLTKGFQFHEKVLQRLFKAVTDQSRYAAYVRSRFDFTETLHNKYGSVLLGYVVCAMATMHQKNQTTTAETATAALTCASYTFKTLATAIGKSLWNVKLVFVVGGYTRRLAQLLAALDRADVLVEMQTSCTAQSPIVSRASGAFPVRGNDGKAMSNYEDSFGRIVRSDHIEFVDVPLVLPTGECLCSSMSFYVKPGMNLLILGRNGCGKSSTFRLLGELWPLRGGRIEKPEAEQLYYVPQRPYMYDGTLLEQVIYPLKKKDLTVGEAELYGYLQMAGLDYVFSKLNMSWETRLPWSDDSLSLGEQQRLAMARLFFHRPRFAILDECSSLVDLDVERQMYDRCVELGITVITIAHRRSVWQYHNWILYFDGSGGYMFSPLQYETGASALVLTCVRSASDASLIGTEVRIPITDRLCSEDETVTAKKEPPPKLIQTAQKAEVPKSPRAETVTEKVEREERAKANGDGDGVHGSHRQSRHRRSRKHRASDGNKAVGFETQAETSGGE

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Additional References:
- Leprohon P, Legare D, Girard I, Papadopoulou B, Ouellette M. 2006. Modulation of Leishmania ABC protein gene expression through life stages and among drug-resistant parasites. Eukaryot Cell 5: 1713-1725. <a href=""https://www.ncbi.nlm.nih.gov/pubmed/17030997"
- Andrade-Alviárez, D., Bonive-Boscan, A.D., Cáceres, A.J., Quiñones, W., Gualdrón-López, M., Ginger, M.L., and Michels, P.A.M. (2022). Delineating transitions during the evolution of specialised peroxisomes: Glycosome formation in kinetoplastid and diplonemid protists. Front. Cell Dev. Biol. 10, 979269. <a href= https://www.ncbi.nlm.nih.gov/pubmed/36172271 </a>
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JMRR-UAM === Date/Fecha: 10/01/2026