Published November 21, 2025 | Version v2
Journal article Open

Ocular Adverse Effects of Psychotropic Drugs: A Clinical Study of 20 Cases (2023–2025)

  • 1. Department of Ophthalmology, Specialty Hospital of Rabat, Mohammed V University – Faculty of Medicine and Pharmacy, Rabat, Morocco
  • 2. Department of Ophthalmology, Hassan II Military Hospital, Faculty of Medicine and Pharmacy, Ibn Zohr University, Laâyoune, Morocco

Description

Abstract:

Purpose: To analyze the ocular adverse effects induced by psychotropic medications and describe their mechanisms according to drug classes.

Methods: A retrospective descriptive study involving 20 patients followed between January 2023 and June 2025 for ocular manifestations secondary to psychotropic therapy.

Results: The mean age was 49 years (18–72), with a female predominance (60%). Neuroleptics accounted for 40% of prescriptions, antidepressants for 30%, anxiolytics for 20%, and mood stabilizers for 10%. The most frequent ocular effects were dry eye (45%), accommodative disorders (25%), ocular hypertension or acute glaucoma (15%), corneal deposits (10%), and retinal changes (5%).

Conclusion: Psychotropic drugs may cause a wide range of ocular side effects. Early detection and collaboration between psychiatrists and ophthalmologists are essential to prevent visual complications.

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