mOTUs - taxonomic meta-omics profiling using universal marker genes

There is a newer version of the record available.

Published November 21, 2025 | Version 4.0
Dataset Open

mOTUs annotation database (v4)

Authors/Creators

  • 1. ROR icon ETH Zurich
  • 2. ROR icon SIB Swiss Institute of Bioinformatics
  • 3. ROR icon Keio University
  • 4. ROR icon Leiden University

Description

Annotation Database for the marker gene-based OTU (mOTU) tool (v4). The mOTUs profiler is a computational tool that estimates relative abundance of known and unknown microbial community members using metagenomic shotgun sequencing data. The annotation database aggregates KEGG, PFAM and EGGNOG annotations for all genomes in the mOTUs-db into a single database. Annotations are then accessible via the mOTUs tool.

Github directory of the tool: link

In the current version, 124,295 species-level taxonomic units (mOTUs) were constructed using sequences of 10 single-copy marker genes recovered from mOTUs-db, a collection of 2.83 million metagenome-assembled genomes (MAGs) and 919 090 single-cell and isolate genomes. 30,256 mOTUs are represented by an isolate genome, whereas 94,039 mOTUs are represented by MAGs only. The source genome database is accessible at https://motus-db.org/. 

Files

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Additional details

Software

Repository URL
https://github.com/motu-tool/mOTUs/
Programming language
Python
Development Status
Active