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This review critically assesses the role of microorganisms and plants in synthesizing nanoparticles, highlighting the potential of chemical approaches in nanotechnology. Green synthesis of nanoparticles is a promising area in nanoscience and technology, focusing on developing clean, biocompatible, non-toxic, and eco-friendly methods. Various types of nanoparticles with specific chemical compositions, sizes, and morphologies have been synthesized using various microorganisms. These nanoparticles have applications in various technological areas, including diagnosis, treatment, drug delivery, medical device coating, wound dressings, medical textiles, contraceptive devices, anti-fungal, and anti-inflammatory applications. Future prospects for synthesis using bacteria are also discussed. This paper discusses the recent developments in biosynthesis of inorganic nanoparticles, including metallic, oxide, and sulfide nanoparticles, using microorganisms. Nanotechnology advancements focus on synthesis of nanoparticles using eco-friendly, reliable techniques. Numerous microorganisms, such as viruses, microalgae, fungus, yeast, bacteria,and  have been explored for metal, oxide of metal, and additional nanomaterials. Genetic engineering can enhance their capacity for nanoparticle synthesis making them quicker, safer, and more environmentally friendly.

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