Prevalence of Relapse of Mania, Sociodemographic and Clinical Parameters in Relapse of Mania in A Tertiary Care Hospital in North Kerala

Aim: To assess the prevalence of relapse of mania. We also explained various socio-demographic and clinical parameters associated with relapse of mania.

Methods: It was a hospital based cross- sectional study on 180 BPAD patients who attended psychiatry department. The patients were assessed with socio-demographic proforma, young mania rating scale for assessment of relapse. Statistical analysis was done using SPSS statistical version 24 software. Manic episodes among BPAD patients were expressed as frequency and percentage. Associated socio-demographic and clinical factors were expressed as frequency and percentage.  Prevalence of relapse of mania, socio-demographic and clinical factors associated with relapse was studied by using Chi square test t-test Probability value ‘p’ < 0.05 considered statistically significant.

Results: In this study, 28.33% patients having relapse of mania. This rate is analogous to previous research by Hebte et al., which reported a relapse rate of 25.52%, Perlis et al., who calculated a 1-year relapse rate of 48.5%, and Vázquez et al.'s review, which estimated recurrence rates of 26.3% among the naturalistic studies examined.

In this study, 12.22% of patients were aged <25 years, 27.22% of patients aged between 25-35 years, 19.44% of patients aged between 35-45 years, Mean age in this study was 41.41±12.45 years. Mean age in relapse group was 41.31±12.55 year.

Conclusion: Prevalence of relapse of mania in this study was 28.33%. Younger age of onset of disease, broken family, stressful life events, family history of psychiatric illness, past history of psychiatric illness, and substance abuse were some of the risk factors associated with relapse of mania.