Dexmedetomidine versus Morphine: The New versus the Old — Choosing the Optimal Hemodynamic and Analgesic Profile for Cesarean Section

ABSTRACT

With the rising global rates of cesarean sections, identifying safe and effective spinal anesthesia strategies has become increasingly important. This study, conducted at the Republican Perinatal Center of Uzbekistan, aimed to compare the hemodynamic and analgesic profiles of two intrathecal adjuvants - morphine and dexmedetomidine - in pregnant women with severe preeclampsia. Sixty patients were divided into two groups. The study evaluated anesthesia quality, postoperative pain management, side effects, and neonatal outcomes. Findings indicated that dexmedetomidine provided comparable analgesic efficacy to morphine with significantly fewer side effects, supporting its potential as a favorable adjuvant for spinal anesthesia in obstetric practice.

Keywords: Spinal anesthesia, Dexmedetomidine, Morphine, Cesarean section, Obstetric anesthesia, Preeclampsia, Postoperative analgesia, side effects, Bupivacaine, Neonatal outcomes.