Published August 4, 2025 | Version v1

Publication Open

COLLAGEN AS A STRUCTURAL COMPONENT OF BONE AND ITS DEGRADATION IN INFLAMMATION

Kim Oksana Vladislavovna Samarkand State Medical University

Abstract: Type I collagen forms the basis of the organic matrix of bone tissue and plays a key role in ensuring its strength, elasticity, and resistance to mechanical stress. In inflammatory processes, such as acute hematogenous osteomyelitis, the degradation of collagen fibers is activated, which disrupts the structural integrity of bone tissue. This article explores the structure and functions of type I collagen in bone tissue, as well as the mechanisms of its degradation during inflammation and the diagnostic significance of its degradation products.

Keywords: type I collagen, bone, osteomyelitis, inflammation, degradation, osteoclasts, markers of bone metabolism

Files

14-16.pdf

Files (372.7 kB)

Name	Size	Download all
14-16.pdf md5:03da86d9dc20572b4b08b3436322538f	372.7 kB	Preview Download

33

Views

57

Downloads

Show more details

	All versions	This version
Views	33	33
Downloads	57	57
Data volume	23.9 MB	23.9 MB

More info on how stats are collected....

DOI

Resource type

Publication

Publisher

Zenodo

License: Creative Commons Attribution 4.0 International

The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited. Read more

Technical metadata

Created: August 4, 2025
Modified: August 4, 2025