Predicted structural models of HCMV gH in complex with partners gpUL141 or gpUL116, and gB in complex with gpUL141 July 2025 - Stephen C. Graham === The structures of HCMV gH (UniProt Q6SW67 residues 25–719) in complex with gpUL141 (UniProt Q6RJQ3 residues 37–278) or gpUL116 (UniProt Q6SW34 residues 25–313), and of a trimer of gpUL141 in complex with a trimer of gB (UniProt F5HB53 residues 25–751), were predicted using AlphaFold3 (AF3). ==> The top model for each is provided (*_model_0.cif), along with the relevant quality statistics (*full_data_0.json and *_summary_confidences_0.json) and the AF3 job request (*_job_request.json). Predicted complexes are in separate directories, compressed as zip files, as follows: - HCMV_gB-x3_pUL141-x2: 3x gB + 3x gpUL141 - HCMV_pUL116_gH: 1x gpUL116 + 1x gH - HCMV_pUL141-x2_gH: 2x gpUL141 + 1x gH - HCMV_pUL141-x2_gH-x2: 2x gpUL141 + 2x gH ==> For convenience, the zip compressed directory "Superposed_models" contains the AlphaFold predictions superposed onto the reference prediction (HCMV_pUL141-x2_gH), with other experimental structures of gH-containing complexes from HCMV similarly superposed. For these experimental structures, the first 4 digits of the file name denote the relevant entry in the Protein Data Bank (PDB; https://www.rcsb.org/) Use of the AlphaFold models is subject to the terms listed in AF3_terms_of_use.md