EVIDENCE: {'Observed_samples': {'Present_SOLO_SR': 2658, 'Present_SOLO_R': 2125, 'Present_SOLO_S': 533}, 'Additional grading criteria applied': None, 'FINAL CONFIDENCE GRADING': '1) Assoc w R', 'INITIAL CONFIDENCE GRADING': '1) Assoc w R', 'WHO HGVS': 'embB_p.Met306Val'}