"metabolite","contrast","logFC","fold_change","AveExpr","t","P.Value","adj.P.Val","significant","B"
"Itaconate","KO_vs_WT_Unstimulated",4.88588003765298,29.5662637350522,28.1465767010576,18.5278887711424,3.80471070979956e-14,8.75083463253899e-12,TRUE,22.5078076445685
"C9H13N5O3(4)","KO_vs_WT_Unstimulated",3.67653364617721,12.7863594033621,21.2777997376967,17.4000491133751,1.25929296572639e-13,1.44818691058534e-11,TRUE,21.28517085871
"2-deoxy-D-ribose 5-phosphate/2-Deoxy-D-ribose 1-phosphate","KO_vs_WT_Unstimulated",2.14412270194251,4.42023386633779,23.680114539021,12.8208665770482,3.66239045207361e-11,2.8078326799231e-09,TRUE,15.4589769041745
"dGDP/ADP","KO_vs_WT_Unstimulated",1.60465248716607,3.04122485548103,25.4032230151934,10.9279158421966,6.24874310788065e-10,3.59302728703137e-08,TRUE,12.5344289387405
"G6P/F6P","KO_vs_WT_Unstimulated",1.03554597243658,2.04988925785911,25.0802027080474,6.97364859967292,8.59911108574995e-07,3.32461014442981e-05,TRUE,5.09211111707124
"gama-L-glutamyl-L-alpha-aminobutyrate","KO_vs_WT_Unstimulated",1.90461891359995,3.74409985900687,21.3734262566277,6.96954806021212,8.67289602894733e-07,3.32461014442981e-05,TRUE,5.08334713290526
"N-acetyl-seryl-aspartate","KO_vs_WT_Unstimulated",0.856566428634643,1.81072370968908,21.7891996031764,6.54850779143195,2.11021227385672e-06,6.93355461410065e-05,TRUE,4.17211068119394
"N(omega)-(L-Arginino)succinate","KO_vs_WT_Unstimulated",1.16515423449093,2.24257189032941,21.519038331953,6.41074070103773,2.83708944511015e-06,8.15663215469168e-05,TRUE,3.86917718789819
"GSSG","KO_vs_WT_Unstimulated",1.19748315200799,2.29339228951114,25.4743948710817,6.31419524861039,3.49613702154797e-06,8.93457238840036e-05,TRUE,3.65553113286578
"dGTP/ATP","KO_vs_WT_Unstimulated",1.97322674672969,3.92645332309918,24.2153931487239,5.83226080533203,1.00911871677181e-05,0.000232097304857517,TRUE,2.57325931248372
"pentadecanoate","KO_vs_WT_Unstimulated",-0.372503042079906,0.77244116620138,25.3648441715071,-5.65321786527673,1.50663361660887e-05,0.000310066077463003,TRUE,2.16498384941804
"margarate","KO_vs_WT_Unstimulated",-0.461391206767061,0.726285555681176,23.9044130329142,-5.6216001969534,1.61773605632871e-05,0.000310066077463003,TRUE,2.09256752068533
"lactate","KO_vs_WT_Unstimulated",0.38007540609965,1.30140987513797,33.5296531154711,5.52921348827484,1.9928104671966e-05,0.000352574159580937,TRUE,1.88044837417949
"fumarate","KO_vs_WT_Unstimulated",0.457974991755648,1.37361242248423,26.3252765958458,5.45021841368566,2.38345759998621e-05,0.000381720959253657,TRUE,1.69848703626661
"Sedoheptulose 7-phosphate","KO_vs_WT_Unstimulated",1.33105388261711,2.5158639058721,22.0843927485878,5.4310542572409,2.48948451687168e-05,0.000381720959253657,TRUE,1.65426471847459
"C20H32O3(12)","KO_vs_WT_Unstimulated",1.29089673309099,2.446800936023,21.1518703041675,5.39920951298482,2.67641922133418e-05,0.000384735263066788,TRUE,1.58071540309955
"palmitoleate","KO_vs_WT_Unstimulated",-0.665005743623336,0.630686193537687,25.8530541836814,-5.17136564126594,4.50584866971836e-05,0.000609614820020719,TRUE,1.05225282430684
"N(2)-acetyl-L-ornithine","KO_vs_WT_Unstimulated",0.616883191417536,1.53355848925581,23.1908396608323,5.02329538860113,6.33689419409244e-05,0.000809714258134035,TRUE,0.706974710221616
"N-Carbamoyl-L-aspartate","KO_vs_WT_Unstimulated",1.48204349946552,2.79344129019914,21.3343534059868,4.91096736907632,8.21745516373735e-05,0.000994744572452417,TRUE,0.444250784831315
"L-4-hydroxyglutamate semialdehyde","KO_vs_WT_Unstimulated",0.605041004238252,1.52102198307109,30.5123339999697,4.80446032043787,0.000105224449578683,0.00113572523588696,TRUE,0.194629353804094
"L-glutamate","KO_vs_WT_Unstimulated",0.604809047246892,1.52077745230615,30.5119611140829,4.8031697820036,0.000105540660636784,0.00113572523588696,TRUE,0.191602105198744
"Dihydroxyacetone phosphate (DHAP)","KO_vs_WT_Unstimulated",1.90519053225069,3.74558362466422,25.6335825672591,4.79074523430562,0.000108634587780492,0.00113572523588696,TRUE,0.16245465762702
"oleic acid/elaidate/trans-vaccenate","KO_vs_WT_Unstimulated",-0.531493236244039,0.691838288239214,28.2149794288215,-4.77007108214778,0.00011398761962211,0.0011398761962211,TRUE,0.113942836467677
"palmitate","KO_vs_WT_Unstimulated",-0.43234450621064,0.741056524283849,30.7263249587835,-4.73500800248722,0.000123683687177346,0.00118530200211623,TRUE,0.0316377115540272
"myristate","KO_vs_WT_Unstimulated",-0.264659057064968,0.832395426181352,27.0868288374511,-4.63841758967135,0.000154932393427076,0.0014253780195291,TRUE,-0.195254771584639
"linoleic acid/linoelaidic acid (all trans C18:2)","KO_vs_WT_Unstimulated",-0.725264415265443,0.604886171701016,26.8640632012339,-4.59431004295197,0.000171746434735665,0.00151929538420011,TRUE,-0.298924308344908
"gama-L-glutamyl-L-alanine","KO_vs_WT_Unstimulated",0.770252947204145,1.70556879408746,23.3096200454785,4.5711242735968,0.000181311526040586,0.00154450559219758,TRUE,-0.353430304326715
"lauroyl carnitine","KO_vs_WT_Unstimulated",0.757703769992457,1.69079736600519,22.2701749093408,4.5440456220265,0.000193165123491982,0.00158671351439843,TRUE,-0.417094741387094
"NN-dimethylglycine","KO_vs_WT_Unstimulated",0.461259572717992,1.37674328584798,24.3108875050165,4.45048972047255,0.00024046648004856,0.00186718803510346,TRUE,-0.637080016618603
"UDP-D-glucose/UDP-D-galactose","KO_vs_WT_Unstimulated",0.653076781221284,1.57251827255654,25.9260015748912,4.44505838246807,0.000243546265448277,0.00186718803510346,TRUE,-0.649851101127508
"CMP-N-acetyl-beta-neuraminate","KO_vs_WT_Unstimulated",0.582218844756795,1.49715007469802,23.1780973431058,4.40086266497703,0.000270128895652475,0.00191307986634165,TRUE,-0.753765151134915
"D-Glucosamine 6-phosphate","KO_vs_WT_Unstimulated",0.573906326654761,1.48854860143863,23.2533595734842,4.39537218270392,0.000273628943656936,0.00191307986634165,TRUE,-0.766673400852772
"N-acetyl-L-glutamate","KO_vs_WT_Unstimulated",0.642937937549679,1.56150581026891,24.5336712561339,4.39403946784324,0.000274485372127281,0.00191307986634165,TRUE,-0.769806597622064
"dGMP/AMP","KO_vs_WT_Unstimulated",-0.539553064074703,0.687984008260836,28.9451607719735,-4.37833497427509,0.000284782697614431,0.00192647118974468,TRUE,-0.806726183516741
"C4H9NO2(4)","KO_vs_WT_Unstimulated",0.463960097138319,1.37932277122326,24.2717883394133,4.35490162307121,0.000300874324541118,0.00197717413269877,TRUE,-0.861809596844628
"UTP","KO_vs_WT_Unstimulated",2.55675425068687,5.88382464475638,21.3662155000295,4.2953801705897,0.00034597616843864,0.00216166621326589,TRUE,-1.0016811098863
"3-Keto-beta-D-galactose/L-Gulonolactone","KO_vs_WT_Unstimulated",-0.57357643690591,0.671948962450945,23.6979158806288,-4.28936455992831,0.000350896338273991,0.00216166621326589,TRUE,-1.01581327913797
"dUDP","KO_vs_WT_Unstimulated",1.14879536469892,2.21728675966446,20.1617989421111,4.28184571449018,0.000357144852626538,0.00216166621326589,TRUE,-1.0334756941241
"malate","KO_vs_WT_Unstimulated",0.44445821499183,1.36080298899882,28.4796160245913,4.21192642510764,0.000420869212200429,0.00248204920015638,TRUE,-1.1976466332914
"UDP","KO_vs_WT_Unstimulated",0.791210926409526,1.73052637090232,23.828322122344,4.19915658979785,0.000433683255465004,0.00249367871892377,TRUE,-1.22761338838155
"C6H12O6(5)","KO_vs_WT_Unstimulated",0.448160825730618,1.36429991296572,29.3514577676548,4.11031505808218,0.000534325537089223,0.00299743593976881,TRUE,-1.4359153996535
"GMP","KO_vs_WT_Unstimulated",-0.807561944292512,0.571346579095283,24.7765998655513,-4.08090176432332,0.000572550331089804,0.00313539467025369,TRUE,-1.50479842603493
"N-acetylneuraminic acid","KO_vs_WT_Unstimulated",0.410421229871368,1.32907381284403,26.9154306087543,4.06189560805143,0.000598691641275389,0.00315221208693064,TRUE,-1.54928446253287
"ADP-ribose","KO_vs_WT_Unstimulated",0.621862726630454,1.53886078959154,23.8086488854893,4.05084056342751,0.000614441846194971,0.00315221208693064,TRUE,-1.57515068182415
"propionyl-carnitine","KO_vs_WT_Unstimulated",1.00990172212737,2.01377391508696,29.0278333207083,4.03688946954567,0.000634909938157779,0.00315221208693064,TRUE,-1.60778276948591
"thiosulfate","KO_vs_WT_Unstimulated",-1.22612064482258,0.427465340825197,20.7226323739901,-4.03347261682438,0.000640025824274187,0.00315221208693064,TRUE,-1.6157731249934
"stearate","KO_vs_WT_Unstimulated",-0.526915067207717,0.694037216918424,28.890748925341,-4.03073943616322,0.000644147687329305,0.00315221208693064,TRUE,-1.62216419124058
"5-methoxytryptophol","KO_vs_WT_Unstimulated",0.306831228128267,1.23698776275909,22.9230463712196,3.91191355953029,0.0008514224614279,0.00407973262767535,TRUE,-1.89952902092324
"alpha-D-glucose","KO_vs_WT_Unstimulated",-0.208380643428999,0.865508178052754,30.5762089227397,-3.85576626341682,0.000971284536371953,0.00455909068092958,TRUE,-2.03020875022547
"NAD+","KO_vs_WT_Unstimulated",0.388497516692279,1.30902941542194,25.2766081645342,3.84119932905416,0.00100503201252587,0.00462314725761902,TRUE,-2.06406717394583
"N-phosphocreatinate","KO_vs_WT_Unstimulated",0.604438619335369,1.520387025997,26.8616459585716,3.81601347519642,0.00106615108830767,0.00480813235903459,TRUE,-2.12256070114783
"5-Methylthioadenosine","KO_vs_WT_Unstimulated",0.56805326167034,1.48252174079203,26.0381699303899,3.64221489152923,0.00160103076901503,0.00708148224756648,TRUE,-2.52436499232176
"myo-inositol","KO_vs_WT_Unstimulated",0.460178995479446,1.37571249249219,29.3025088883801,3.63381970637596,0.00163271613343047,0.00708537189979259,TRUE,-2.54368265382982
"decanoyl carnitine","KO_vs_WT_Unstimulated",0.527097540742023,1.4410271735218,21.0008543743848,3.59069904211856,0.00180548444469609,0.00769002633852038,TRUE,-2.64275667016808
"Diphosphate","KO_vs_WT_Unstimulated",-0.805044928940543,0.572344255866092,21.9858439333209,-3.57402896858944,0.00187700700004789,0.00784930200020028,TRUE,-2.68098899913812
"C20H30O2(4)","KO_vs_WT_Unstimulated",-1.00814743399531,0.497184272760165,22.4691227743669,-3.49443583824792,0.0022588813665673,0.00927754846983,TRUE,-2.86296847990828
"fructose-1,6-bisphosphate","KO_vs_WT_Unstimulated",1.29160948871975,2.4480100633582,22.3727042925681,3.44978391297335,0.00250558855560293,0.0101102696103276,TRUE,-2.96462325871259
"3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid","KO_vs_WT_Unstimulated",-0.318497233704633,0.80190473732697,24.2948820544585,-3.42638427406385,0.00264525626578189,0.0104898093298247,TRUE,-3.01776151961338
"Eicosenoic acid","KO_vs_WT_Unstimulated",-0.464050499518976,0.72494804020466,22.6659797553651,-3.38883096431209,0.00288552825156308,0.0112486694552459,TRUE,-3.10284079622371
"trans-Hexadec-2-enoyl carnitine","KO_vs_WT_Unstimulated",0.907547628500691,1.87585410790576,24.567027253297,3.3357688273684,0.00326185321353921,0.0125037706519003,TRUE,-3.22261477793243
"clupanodonic acid","KO_vs_WT_Unstimulated",-0.839834510139589,0.558707654061877,24.372024146471,-3.28225654769482,0.00368987867946969,0.0139126573160333,TRUE,-3.34285036641207
"sn-Glycero-3-phosphocholine","KO_vs_WT_Unstimulated",0.521222371213781,1.43517072900585,32.466666435763,3.21012417425572,0.00435455171598753,0.0161539821722118,TRUE,-3.50397954455261
"pyruvate","KO_vs_WT_Unstimulated",-0.66383309952689,0.631199033097676,24.0042663830927,-3.17421391636263,0.00472757787180042,0.0172594112780015,TRUE,-3.58376717843168
"Folate","KO_vs_WT_Unstimulated",-0.389444301638225,0.763423603933576,24.7013341507247,-3.1582132720488,0.0049036278120559,0.0174236087026096,TRUE,-3.61922248727868
"butyryl carnitine","KO_vs_WT_Unstimulated",0.318115288841959,1.24670081681944,27.952615327755,3.15639223425629,0.00492406332899838,0.0174236087026096,TRUE,-3.62325384710264
"L-tyrosine","KO_vs_WT_Unstimulated",-0.164828030194421,0.892034843980622,31.5487443471913,-3.13863089153679,0.00512776646970402,0.0178694892126049,TRUE,-3.66253194942496
"omega hydroxy hexadecanoate (n-C16:0)","KO_vs_WT_Unstimulated",-0.216533610805751,0.86063080723545,23.0956209383254,-3.12862534357549,0.00524609707268568,0.0180089899510105,TRUE,-3.68462515771762
"anthranilate","KO_vs_WT_Unstimulated",-0.42822738608097,0.743174349773056,24.0424391132574,-3.10864919138055,0.00549032069318503,0.0185702023445964,TRUE,-3.72866114356656
"L-erythrulose","KO_vs_WT_Unstimulated",-0.176820359442395,0.884650582816488,27.8243836763563,-3.05160490527055,0.00624993108219994,0.0208331036073331,TRUE,-3.85385757087463
"L-threonine","KO_vs_WT_Unstimulated",-0.186231280912114,0.878898651869717,29.495103722802,-3.02191604029741,0.00668453303550811,0.0219353220869376,TRUE,-3.91868027350166
"choline","KO_vs_WT_Unstimulated",-0.193663111385767,0.874382776661898,32.6192573184174,-3.01621019046469,0.00677133855727203,0.0219353220869376,TRUE,-3.9311112652634
"Riboflavin","KO_vs_WT_Unstimulated",0.391076907647687,1.31137191938518,25.4823656938428,3.00516822222071,0.00694242529727265,0.0221771919218432,TRUE,-3.95514248663304
"5-guanidino-2-oxopentanoic acid","KO_vs_WT_Unstimulated",-0.648553891376906,0.637919422108539,21.4314436045721,-2.98177552042593,0.00731875992599141,0.0230591066161373,TRUE,-4.00594186039406
"tetradecanoyl carnitine(myristoyl carnitine)","KO_vs_WT_Unstimulated",0.697088136376209,1.62122928004256,25.054969069724,2.95842306089845,0.00771401862539948,0.0239760038357011,TRUE,-4.0565000906511
"D-Glycerate 3-phosphate/D-Glycerate 2-phosphate","KO_vs_WT_Unstimulated",1.07131633591577,2.10134979490769,23.2210633158613,2.90874021776055,0.00862441361423171,0.0264482017503106,TRUE,-4.1635370921525
"C5H10O5(6)","KO_vs_WT_Unstimulated",-0.197434602988949,0.872099951461039,25.9421043976103,-2.89016360591604,0.0089906368110373,0.0272085061386655,TRUE,-4.20336936304723
"uridine","KO_vs_WT_Unstimulated",-1.04499097444419,0.484647940434254,23.7992033419126,-2.86606927108988,0.00948790499432424,0.0283404954375919,TRUE,-4.25487502147096
"3-hydroxy-isovaleryl carnitine","KO_vs_WT_Unstimulated",0.344631716956265,1.26982678694916,25.0355268594957,2.83155732828995,0.0102462952005589,0.0302134345657507,TRUE,-4.32833241247947
"pentadenoyl carnitine","KO_vs_WT_Unstimulated",0.78356942219877,1.72138454626426,22.5849223196189,2.77170530463806,0.0117008369795018,0.0340657279150052,TRUE,-4.45480702004769
"Glycerol 3-phosphate","KO_vs_WT_Unstimulated",0.439543936084522,1.35617554625495,26.4455011419812,2.76061310216517,0.0119911943102899,0.0344746836420834,TRUE,-4.47811433886881
"citrulline","KO_vs_WT_Unstimulated",1.05848061790734,2.0827369205938,25.4400786293318,2.72829997690629,0.0128766574821771,0.0365633484061818,TRUE,-4.54576986395184
"4-hydroperoxy-2-nonenal","KO_vs_WT_Unstimulated",-0.24190239102613,0.845629498522695,21.9586353947342,-2.68871578333829,0.0140461682306192,0.0393977889395417,TRUE,-4.62814683633106
"Linoleyl carnitine/Linoelaidyl carnitine","KO_vs_WT_Unstimulated",0.774362859706635,1.7104345019336,22.5544293565265,2.66691277644417,0.0147326688514943,0.0408254679017313,TRUE,-4.67327778385421
"2-methylglutaconic acid","KO_vs_WT_Unstimulated",-0.152491465854148,0.899695388997861,28.0911949575773,-2.63601525690242,0.0157601168996504,0.0431527010347572,TRUE,-4.73693158557102