"finding","description"
"Top enriched pathway in unstimulated condition","Glycolysis"
"Top enriched pathway in LPS 6hr","Glycolysis"
"Top enriched pathway in LPS 24hr","Lipid Metabolism"
"Consistently enriched pathways across conditions","No consistently enriched pathways"
"Pathways showing treatment-specific enrichment","Unstimulated: Glycolysis"
"Key upregulated metabolite in KO vs WT (Unstimulated)","Itaconate (logFC = 4.89, padj = 8.75e-12)"
"Key downregulated metabolite in KO vs WT (Unstimulated)","pentadecanoate (logFC = -0.37, padj = 3.10e-04)"
"Key upregulated metabolite in KO vs WT (LPS 24hr)","lactate (logFC = 1.43, padj = 9.79e-13)"
"Key downregulated metabolite in KO vs WT (LPS 24hr)","palmitoleate (logFC = -1.92, padj = 1.23e-10)"
"Consistently differentially abundant metabolites","2-deoxy-D-ribose 5-phosphate/2-Deoxy-D-ribose 1-phosphate, N(2)-acetyl-L-ornithine, D-Glucosamine 6-phosphate, N-acetylneuraminic acid, Itaconate"
"Unstimulated-specific metabolites","dGDP/ADP, dGTP/ATP, pentadecanoate"
"LPS 24hr-specific metabolites","arginine, UMP, indole-3-acetate/(5-hydroxyindol-3-yl)acetaldehyde"
"Most significantly enriched pathway: Glycolysis","Comparison: KO vs WT Unstimulated, p-value: 2.92e-02, fold enrichment: 2.05"