Table 2. Molecular docking dissociation constants (mM) and distances (Å) for oxy and met forms of tyrosinase. Distances greater than 4 Å have not been considered.;;;;;;;;;;;
Ligand;Oxy form;;;;;Met form;;;;;
;Kd ;d(O2-HO);d(O2-oC);d(Cu-OH);d(π-π);Kd;d(OH-OH);d(Cu-OH);d(π-π);;
Ferulic acid;7.8;1.8;3.3;3.3;NA;4.8;2.1;2.6;NA;;
Thymol;0.61;1.7;3.9;3.4;NA;0.92;2.1;3.4;NA;;
Carvacrol;0.9;1.7;3.5;NA;NA;0.84;1.9;2.8;3.5;;
Guaiacol;7.3;1.7;3.9;3.4;NA;2.2;1.6;3.1;3.3;;
Eugenol;3.9;1.7;3.8;3.4;NA;0.63;1.6;2.5;3.6;;
Isoeugenol;3;1.8;3.6;3.4;NA;2.4;1.9;2.8;NA;;
d(O2-HO):   minimum distance from O atom of peroxide group of tyrosinase to H atom of phenolic group of ligand;;;;;;;;;;;
d(O2-oC):   minimum distance from O atom of peroxide group of tyrosinase to carbon atom of ligand in ortho position with respect to the phenolic group;;;;;;;;;;;
d(Cu-OH):  minimum distance from a Cu atom of tyrosinase to O atom of phenolic group of ligand;;;;;;;;;;;
d(π-π):       distance from the center of the imidazole ring of H263 to the center of the aromatic ring of the ligand;;;;;;;;;;;
d(OH-OH): minimum distance from H atom of hydroxyl group of tyrosinase to O atom of phenolic group of ligand;;;;;;;;;;;