GENE_ID,GENE_NAME,GENE_DESCRIPTION,GENE_FUNCTION,EVIDENCE_SCORE (GetGPT),PUBMED_LINK
1,MECP2,Methyl-CpG-binding protein 2; X-linked gene mutated in classic Rett syndrome,"Regulates gene expression, synaptic plasticity, and BDNF levels",0.88,https://pubmed.ncbi.nlm.nih.gov/10508514/
2,FOXG1,Forkhead box protein G1; transcription factor in brain development,"Regulates early forebrain development, synapse formation",0.72,https://pubmed.ncbi.nlm.nih.gov/22998673/
3,GABBR2,GABA type B receptor subunit 2,Modulates inhibitory synaptic transmission (GABAergic signaling),0.55,https://pubmed.ncbi.nlm.nih.gov/28212680/
4,CDKL5,Cyclin-dependent kinase-like 5,"Regulates synaptic development and function, esp. in early brain",0.41,https://pubmed.ncbi.nlm.nih.gov/15917271/
5,GRIN2A,Regulated by MECP2,Forms NMDA receptors responsible for excitatory synaptic transmission and calcium influx in neurons,0.29,https://pubmed.ncbi.nlm.nih.gov/30544257/
6,IGF1,Insulin-like growth factor 1,"Promotes neuronal survival, synaptic maturation, growth hormone axis",0.08,https://pubmed.ncbi.nlm.nih.gov/28212680/
7,NTNG1,Netrin-G1; axon guidance and neural circuit formation,Axon patterning in the developing brain,0.03,https://pubmed.ncbi.nlm.nih.gov/28212680/
8,STXBP1,Syntaxin-binding protein 1,Essential for neurotransmitter release at synapses,0.02,https://pubmed.ncbi.nlm.nih.gov/22998673/
9,PTPN1,Protein tyrosine phosphatase non-receptor type 1,Regulates insulin and growth hormone signaling; linked to metabolism,0.02,https://pubmed.ncbi.nlm.nih.gov/28212680/
10,EGR2,Early growth response 2; transcription factor in nervous system and myelination,Involved in neuronal plasticity and inflammatory response,0.01,https://pubmed.ncbi.nlm.nih.gov/27900411/