This Zenodo deposit contains a publicly available description of the Dataset:
\nTitle: \"Single nuclei sequencing of brain regions from healthy and Parkinson's Disease individuals\".
\nDescription: We performed single nuclei RNA sequencing of postmortem PD and control brain tissue of four different brain regions (substantia nigra, putamen, amygdala, and prefrontal cortex). Briefly, 8500 nuclei were FACS sorted from approximately 2 mm3 of tissue. Single nuclei RNAseq libraries were prepared using 10X genomics platform for single cell 3' sequencing. Sequencing libraries are prepared by fragmentation, end repair and a tailing followed by sample index PCR. To process the data, FASTQ files were processed using Cell Ranger, aligning and quantifying for hg38. Intronic reads were also quantified.
\n\n\n\n", "funding": [ { "award": { "id": "03zj4c476::ASAP-000520", "number": "ASAP-000520", "title": { "en": "Activation of transposable elements as a trigger of neuroinflammation in Parkinson\u2019s disease" } }, "funder": { "id": "03zj4c476", "name": "Aligning Science Across Parkinson's" } } ], "publication_date": "2024-03-06", "publisher": "Zenodo", "references": [ { "reference": "Aligning Science Across Parkinson's Collaborative Research Network Cloud, https://cloud.parkinsonsroadmap.org/collections, RRID:SCR_023923" }, { "reference": "Team Jakobsson" } ], "resource_type": { "id": "dataset", "title": { "de": "Datensatz", "en": "Dataset" } }, "rights": [ { "description": { "en": "The Creative Commons Attribution license allows re-distribution and re-use of a licensed work on the condition that the creator is appropriately credited." }, "icon": "cc-by-icon", "id": "cc-by-4.0", "props": { "scheme": "spdx", "url": "https://creativecommons.org/licenses/by/4.0/legalcode" }, "title": { "en": "Creative Commons Attribution 4.0 International" } } ], "title": "Single nuclei sequencing of brain regions from healthy and Parkinson's Disease individuals", "version": "1.0" }, "parent": { "access": { "owned_by": { "user": "615261" }, "settings": { "accept_conditions_text": null, "allow_guest_requests": false, "allow_user_requests": false, "secret_link_expiration": 0 } }, "communities": { "default": "8d70e99e-d005-4ad3-814b-6560de123def", "entries": [ { "access": { "member_policy": "open", "members_visibility": "public", "record_submission_policy": "open", "review_policy": "members", "visibility": "public" }, "children": { "allow": false }, "created": "2021-03-22T18:04:38.253618+00:00", "custom_fields": {}, "deletion_status": { "is_deleted": false, "status": "P" }, "id": "8d70e99e-d005-4ad3-814b-6560de123def", "links": {}, "metadata": { "curation_policy": "This dataset is made available to researchers via the ASAP CRN Cloud: cloud.parkinsonsroadmap.org. Instructions for how to request access can be found in the User Manual.
\nThis research was funded by the Aligning Science Across Parkinson's Collaborative Research Network (ASAP CRN), through the Michael J. Fox Foundation for Parkinson's Research (MJFF).
\nThis Zenodo deposit was created by the ASAP CRN Cloud staff on behalf of the dataset authors. It provides a citable reference for a CRN Cloud Dataset
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ASAP accepts uploads by ASAP grantees
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